# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF5560 PF17715.1 GAM16826.1 - 0.061 12.8 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5560) DUF2489 PF10675.9 GAM16826.1 - 0.087 12.7 3.9 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF572 PF04502.13 GAM16827.1 - 0.0042 16.8 16.0 0.0051 16.5 16.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) LAP1C PF05609.12 GAM16827.1 - 0.0047 16.1 13.6 0.0054 15.9 13.6 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 GAM16827.1 - 0.015 13.5 16.9 0.022 12.9 16.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOG2 PF10428.9 GAM16827.1 - 0.037 13.2 33.1 0.045 13.0 33.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Suf PF05843.14 GAM16827.1 - 0.043 13.8 9.2 0.084 12.8 9.2 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Utp14 PF04615.13 GAM16827.1 - 0.068 11.7 23.9 0.084 11.4 23.9 1.1 1 0 0 1 1 1 0 Utp14 protein Agenet PF05641.12 GAM16827.1 - 0.19 12.3 0.1 0.34 11.4 0.1 1.4 1 0 0 1 1 1 0 Agenet domain DUF4551 PF15087.6 GAM16827.1 - 0.2 10.5 18.2 0.24 10.2 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Raftlin PF15250.6 GAM16827.1 - 0.2 10.4 12.8 0.27 9.9 12.8 1.2 1 0 0 1 1 1 0 Raftlin GCOM2 PF15328.6 GAM16827.1 - 0.58 10.5 16.0 3.3 8.0 14.0 2.3 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 Ndc1_Nup PF09531.10 GAM16827.1 - 1.5 7.5 16.6 1.9 7.0 16.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 GAM16827.1 - 1.8 7.1 26.9 2.1 6.9 26.9 1.1 1 0 0 1 1 1 0 Hamartin protein GREB1 PF15782.5 GAM16827.1 - 3.8 4.5 23.3 4.6 4.2 23.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 GAM16827.1 - 7.6 5.4 21.1 11 4.9 21.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PPP4R2 PF09184.11 GAM16827.1 - 9.9 5.7 30.1 14 5.2 30.1 1.2 1 0 0 1 1 1 0 PPP4R2 Josephin PF02099.17 GAM16828.1 - 0.073 13.2 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Josephin adh_short_C2 PF13561.6 GAM16829.1 - 1.6e-67 227.5 0.2 2.1e-67 227.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM16829.1 - 9e-55 185.2 0.9 1.1e-54 184.9 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM16829.1 - 3.4e-09 36.9 0.4 6.2e-09 36.0 0.3 1.4 1 1 0 1 1 1 1 KR domain AAA_31 PF13614.6 GAM16829.1 - 0.00015 21.7 1.0 0.00046 20.1 0.2 1.9 2 0 0 2 2 2 1 AAA domain Epimerase PF01370.21 GAM16829.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CbiA PF01656.23 GAM16829.1 - 0.02 15.0 1.1 0.025 14.6 0.2 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain THF_DHG_CYH_C PF02882.19 GAM16829.1 - 0.081 12.2 0.1 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 GAM16829.1 - 0.1 12.5 0.2 0.4 10.5 0.3 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SLC35F PF06027.12 GAM16830.1 - 3.8e-96 322.1 31.0 4.9e-96 321.8 31.0 1.1 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 GAM16830.1 - 6.3e-11 42.6 36.1 4.5e-07 30.1 12.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 GAM16830.1 - 3.5e-09 36.1 20.3 5e-09 35.6 20.3 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 GAM16830.1 - 2.2e-05 23.9 26.1 5.4e-05 22.5 26.1 1.6 1 1 0 1 1 1 1 UAA transporter family PCI PF01399.27 GAM16831.1 - 9.5e-15 55.0 0.9 6.6e-14 52.3 0.1 2.7 3 0 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 GAM16831.1 - 3.2e-11 42.7 1.9 8.8e-11 41.3 1.9 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Tenui_NS3 PF05310.12 GAM16831.1 - 0.025 14.7 0.4 0.057 13.5 0.1 1.8 1 1 1 2 2 2 0 Tenuivirus movement protein RraB PF06877.11 GAM16831.1 - 0.17 12.6 2.5 0.3 11.8 0.1 2.5 3 0 0 3 3 3 0 Regulator of ribonuclease activity B TehB PF03848.14 GAM16832.1 - 8.1e-05 22.1 0.0 0.00037 19.9 0.0 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.6 GAM16832.1 - 0.00013 22.6 0.0 0.00032 21.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM16832.1 - 0.00014 21.7 0.0 0.00048 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 GAM16832.1 - 0.0014 18.1 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_31 PF13847.6 GAM16832.1 - 0.0025 17.6 0.0 0.0069 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAM16832.1 - 0.0062 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 GAM16832.1 - 0.034 14.8 0.0 0.084 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 GAM16832.1 - 0.037 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 GAM16832.1 - 0.075 13.8 0.0 0.3 11.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Rhodanese PF00581.20 GAM16832.1 - 0.18 12.3 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 Rhodanese-like domain UBX PF00789.20 GAM16833.1 - 5.6e-11 42.5 0.0 1.1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain Neur_chan_memb PF02932.16 GAM16833.1 - 0.096 12.7 4.9 0.63 10.0 0.9 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Thioredox_DsbH PF03190.15 GAM16833.1 - 0.14 12.1 1.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF255 Lip_prot_lig_C PF10437.9 GAM16834.1 - 3.6e-20 71.7 0.0 1e-19 70.3 0.0 1.8 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 GAM16834.1 - 7.7e-07 29.1 0.0 4.7e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family FANCF PF11107.8 GAM16835.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) FANCI_S2 PF14676.6 GAM16835.1 - 0.15 12.3 6.0 5 7.4 0.0 3.7 2 2 1 4 4 4 0 FANCI solenoid 2 bZIP_1 PF00170.21 GAM16836.1 - 1.2e-09 38.1 9.9 1.1e-08 35.1 6.1 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAM16836.1 - 1.5e-05 25.0 5.4 1.5e-05 25.0 5.4 2.5 3 0 0 3 3 3 1 Basic region leucine zipper DUF4763 PF15960.5 GAM16836.1 - 1.8 7.8 14.9 0.47 9.7 4.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) ORC6 PF05460.13 GAM16836.1 - 3.9 6.6 28.8 2 7.6 27.0 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RNA_pol_Rpb4 PF03874.16 GAM16836.1 - 5.5 7.3 11.2 0.49 10.7 2.7 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 V_ATPase_I PF01496.19 GAM16836.1 - 9.6 4.0 13.1 5.9 4.7 11.4 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec7 PF01369.20 GAM16837.1 - 1.5e-30 106.3 2.1 3.3e-30 105.1 2.1 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAM16837.1 - 2.1e-23 83.0 7.1 2.1e-23 83.0 7.1 2.9 3 1 1 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal VIT1 PF01988.19 GAM16838.1 - 7.9e-54 182.8 3.9 7.9e-54 182.8 3.9 1.6 2 0 0 2 2 2 1 VIT family MlrC_C PF07171.12 GAM16838.1 - 0.0065 16.6 0.2 0.011 15.9 0.2 1.3 1 0 0 1 1 1 1 MlrC C-terminus TRAM_LAG1_CLN8 PF03798.16 GAM16838.1 - 0.011 15.5 0.5 0.018 14.8 0.5 1.3 1 0 0 1 1 1 0 TLC domain DUF2207 PF09972.9 GAM16838.1 - 0.91 8.2 10.1 0.93 8.2 0.0 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) FRQ PF09421.10 GAM16838.1 - 1.2 7.1 3.5 1.6 6.7 3.5 1.0 1 0 0 1 1 1 0 Frequency clock protein DPBB_1 PF03330.18 GAM16839.1 - 0.013 15.7 1.0 0.28 11.5 0.5 2.8 2 1 0 2 2 2 0 Lytic transglycolase zf-CCHH PF10283.9 GAM16839.1 - 0.1 12.6 0.5 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 PBZ domain DPBB_1 PF03330.18 GAM16840.1 - 0.12 12.6 1.1 1.2 9.5 1.1 2.4 1 1 0 1 1 1 0 Lytic transglycolase PsbP PF01789.16 GAM16841.1 - 1.2e-08 35.2 1.2 2.6e-05 24.4 0.0 3.4 2 1 0 2 2 2 2 PsbP RRM_1 PF00076.22 GAM16842.1 - 6.7e-16 57.9 0.1 9.6e-16 57.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM16842.1 - 0.059 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF4756 PF15948.5 GAM16844.1 - 0.025 14.4 0.1 0.087 12.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) NAD_binding_2 PF03446.15 GAM16844.1 - 0.1 12.8 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SpoIIE PF07228.12 GAM16845.1 - 2.2e-09 37.5 0.0 5.3e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAM16845.1 - 0.00026 20.7 0.0 0.00026 20.7 0.0 2.2 3 0 0 3 3 3 1 Protein phosphatase 2C PP2C PF00481.21 GAM16845.1 - 0.00043 20.0 7.2 0.035 13.7 0.0 3.0 3 1 0 3 3 3 2 Protein phosphatase 2C NDUF_B4 PF07225.12 GAM16846.1 - 0.054 13.4 0.0 0.058 13.3 0.0 1.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Adap_comp_sub PF00928.21 GAM16847.1 - 1.2e-19 70.7 1.0 3.9e-19 69.0 0.1 2.0 2 0 0 2 2 2 1 Adaptor complexes medium subunit family CBS PF00571.28 GAM16848.1 - 3.9e-32 110.5 0.8 3.1e-10 40.3 0.0 4.2 4 0 0 4 4 4 4 CBS domain PTEN_C2 PF10409.9 GAM16849.1 - 6.7e-18 64.7 7.0 2.7e-17 62.8 2.9 2.3 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 GAM16849.1 - 2.5e-06 27.3 0.0 7e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAM16849.1 - 3e-05 24.2 0.0 6.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 GAM16849.1 - 7.6e-05 22.4 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAM16849.1 - 0.0021 18.1 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 GAM16849.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) SUIM_assoc PF16619.5 GAM16849.1 - 0.036 14.1 4.5 0.039 14.0 1.3 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RNA12 PF10443.9 GAM16850.1 - 8.3e-56 189.6 0.1 1e-26 93.7 0.0 3.0 1 1 1 2 2 2 2 RNA12 protein RRM_1 PF00076.22 GAM16850.1 - 8.5e-06 25.5 0.0 3.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 GAM16850.1 - 4.6e-05 23.4 0.6 0.0001 22.3 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_35 PF14516.6 GAM16850.1 - 0.0015 17.5 0.0 0.0033 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.6 GAM16850.1 - 0.0023 18.3 0.0 0.0052 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 GAM16850.1 - 0.025 15.1 2.6 4 7.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAM16850.1 - 0.026 15.0 0.0 0.1 13.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 GAM16850.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3446 PF11928.8 GAM16850.1 - 0.15 12.4 1.0 0.39 11.0 1.0 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain FapA PF03961.13 GAM16850.1 - 0.28 9.8 3.0 0.42 9.2 3.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A PAPA-1 PF04795.12 GAM16850.1 - 8.1 7.3 8.0 17 6.3 6.4 2.4 2 0 0 2 2 2 0 PAPA-1-like conserved region Methyltransf_16 PF10294.9 GAM16851.1 - 7e-18 65.0 0.1 1e-09 38.3 0.1 2.4 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 GAM16851.1 - 0.011 15.6 0.1 0.91 9.3 0.1 2.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAM16851.1 - 3.8 8.3 4.6 3.9 8.3 0.1 2.8 2 1 1 3 3 3 0 Methyltransferase domain Kelch_6 PF13964.6 GAM16852.1 - 1.4e-23 82.3 2.8 0.00015 21.9 0.0 7.0 5 1 2 7 7 7 5 Kelch motif Kelch_1 PF01344.25 GAM16852.1 - 1.1e-17 63.3 2.0 0.00068 19.2 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 GAM16852.1 - 4.1e-14 52.3 2.2 0.025 14.6 0.0 6.0 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM16852.1 - 4.2e-10 39.2 1.2 0.15 12.1 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAM16852.1 - 3.2e-09 36.8 0.0 2.1 8.8 0.0 6.0 5 0 0 5 5 5 3 Galactose oxidase, central domain zf-RING_UBOX PF13445.6 GAM16852.1 - 3.3e-06 27.0 10.3 3.3e-06 27.0 10.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Kelch_5 PF13854.6 GAM16852.1 - 3.9e-06 26.7 0.0 0.043 13.8 0.1 3.0 2 0 0 2 2 2 2 Kelch motif zf-C3HC4_4 PF15227.6 GAM16852.1 - 7e-06 26.1 12.1 7e-06 26.1 12.1 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 GAM16852.1 - 7.3e-06 25.8 8.3 7.3e-06 25.8 8.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-B_box PF00643.24 GAM16852.1 - 1.2e-05 25.4 7.9 1.2e-05 25.4 7.9 2.7 2 0 0 2 2 2 1 B-box zinc finger zf-C3HC4 PF00097.25 GAM16852.1 - 0.00034 20.4 10.7 0.00034 20.4 10.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GAM16852.1 - 0.00086 19.1 3.6 0.00086 19.1 3.6 2.5 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 GAM16852.1 - 0.0054 17.0 9.7 0.0054 17.0 9.7 2.5 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 GAM16852.1 - 0.0072 16.2 8.8 0.0072 16.2 8.8 2.6 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAM16852.1 - 0.0096 15.8 7.4 0.0096 15.8 7.4 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) EDR1 PF14381.6 GAM16852.1 - 0.026 14.2 0.9 0.067 12.9 0.9 1.7 1 1 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 WHEP-TRS PF00458.20 GAM16852.1 - 0.075 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 WHEP-TRS domain DUF2963 PF11178.8 GAM16852.1 - 6.4 6.6 6.8 21 4.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) Sod_Cu PF00080.20 GAM16853.1 - 2.6e-15 56.8 0.1 4.1e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 GAM16853.1 - 0.00058 20.2 1.2 0.0012 19.3 1.2 1.5 1 1 0 1 1 1 1 Heavy-metal-associated domain DUF1279 PF06916.13 GAM16854.1 - 4.3e-17 62.5 1.3 9.1e-17 61.4 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Pex14_N PF04695.13 GAM16854.1 - 0.0013 19.5 4.7 0.0019 18.9 4.7 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3464 PF11947.8 GAM16854.1 - 0.0027 17.5 0.1 0.0044 16.8 0.1 1.3 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 SpoVAB PF13782.6 GAM16854.1 - 0.0038 17.5 0.4 0.0066 16.7 0.4 1.3 1 0 0 1 1 1 1 Stage V sporulation protein AB TFIIA PF03153.13 GAM16854.1 - 0.039 14.0 14.5 0.046 13.7 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 GAM16854.1 - 0.061 12.1 0.5 0.072 11.8 0.5 1.3 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 GAM16854.1 - 0.07 12.9 2.3 0.095 12.5 2.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.12 GAM16854.1 - 0.094 12.5 1.3 0.12 12.1 1.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 GAM16854.1 - 0.12 12.4 10.1 0.15 12.0 10.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 GAM16854.1 - 0.2 11.3 21.2 0.3 10.7 21.2 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 GAM16854.1 - 0.53 9.2 17.8 1 8.2 17.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CENP-R PF06729.12 GAM16854.1 - 0.54 10.2 6.9 1 9.3 6.9 1.4 1 0 0 1 1 1 0 Kinetochore component, CENP-R Coilin_N PF15862.5 GAM16854.1 - 0.62 9.9 5.7 1.1 9.0 5.7 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF5327 PF17261.2 GAM16854.1 - 1.4 9.7 10.3 2.4 9.0 10.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5327) DUF5336 PF17270.2 GAM16854.1 - 1.7 8.3 6.1 2.6 7.6 6.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5336) DUF4175 PF13779.6 GAM16854.1 - 5.9 4.7 13.1 7.5 4.3 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PRELI PF04707.14 GAM16855.1 - 2.9e-44 150.7 0.0 4.7e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 PRELI-like family Baculo_PEP_C PF04513.12 GAM16855.1 - 0.027 14.5 0.5 0.041 13.9 0.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 GAM16855.1 - 0.028 14.4 5.1 0.24 11.4 1.9 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ALAD PF00490.21 GAM16855.1 - 0.13 11.4 0.5 0.17 11.0 0.5 1.1 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase CUE PF02845.16 GAM16857.1 - 4.9e-10 38.9 0.1 9.3e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 CUE domain eIF-1a PF01176.19 GAM16858.1 - 1.4e-19 69.6 0.0 2.2e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 XRCC4 PF06632.12 GAM16859.1 - 1.2e-22 80.2 12.3 1.8e-22 79.7 12.3 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 KASH_CCD PF14662.6 GAM16859.1 - 0.00074 19.4 8.9 0.0014 18.5 8.9 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH NYD-SP28_assoc PF14775.6 GAM16859.1 - 0.00094 19.2 5.6 0.3 11.2 0.8 2.5 2 0 0 2 2 2 2 Sperm tail C-terminal domain bZIP_1 PF00170.21 GAM16859.1 - 0.015 15.4 0.3 0.015 15.4 0.3 3.6 3 1 0 3 3 3 0 bZIP transcription factor Chitin_synth_1N PF08407.11 GAM16859.1 - 0.11 12.4 2.7 0.22 11.5 0.0 2.6 3 0 0 3 3 3 0 Chitin synthase N-terminal V_ATPase_I PF01496.19 GAM16859.1 - 0.2 9.5 10.5 0.23 9.3 10.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 GAM16859.1 - 0.32 10.8 14.0 0.6 9.9 0.4 3.2 3 0 0 3 3 3 0 Septum formation initiator YlqD PF11068.8 GAM16859.1 - 1.4 9.3 14.8 1.4 9.3 7.6 2.3 2 0 0 2 2 2 0 YlqD protein TSC22 PF01166.18 GAM16859.1 - 1.7 9.0 6.9 10 6.5 0.4 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 GAM16859.1 - 1.9 9.2 13.7 2.2 8.9 1.1 2.5 1 1 0 2 2 2 0 Initiation control protein YabA CENP-Q PF13094.6 GAM16859.1 - 5.7 7.1 16.4 2.1 8.5 0.8 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit 6PGD PF00393.19 GAM16860.1 - 8.8e-127 422.4 0.0 1.1e-126 422.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAM16860.1 - 5.7e-51 172.8 0.0 8.2e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAM16860.1 - 0.16 12.2 0.3 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase TPP_enzyme_N PF02776.18 GAM16861.1 - 5.5e-49 166.1 0.0 4.2e-48 163.2 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAM16861.1 - 1.6e-24 86.4 0.0 3.7e-23 82.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM16861.1 - 1.2e-18 67.1 0.0 3.8e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CBF PF03914.17 GAM16862.1 - 2e-32 112.6 0.2 2e-32 112.6 0.2 2.6 2 1 0 2 2 2 1 CBF/Mak21 family EST1 PF10374.9 GAM16862.1 - 0.0061 17.2 3.9 0.013 16.1 2.5 2.2 2 0 0 2 2 2 1 Telomerase activating protein Est1 DHquinase_I PF01487.15 GAM16862.1 - 0.022 15.0 1.9 0.057 13.7 1.9 1.8 1 1 0 1 1 1 0 Type I 3-dehydroquinase Glyco_hydro_32C PF08244.12 GAM16862.1 - 0.59 10.1 0.0 0.59 10.1 0.0 3.0 3 0 0 3 3 3 0 Glycosyl hydrolases family 32 C terminal zf-C2H2_jaz PF12171.8 GAM16863.1 - 2.4e-10 40.4 2.4 2.4e-10 40.4 2.4 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAM16863.1 - 0.016 15.5 0.4 0.022 15.1 0.2 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF3449 PF11931.8 GAM16863.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) zf-C2H2_4 PF13894.6 GAM16863.1 - 0.027 15.3 0.2 0.051 14.4 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 GAM16863.1 - 0.038 14.4 0.8 0.074 13.5 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Tom22 PF04281.13 GAM16864.1 - 0.011 15.5 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF678 PF05077.12 GAM16864.1 - 0.027 14.6 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF678) PMD PF10536.9 GAM16864.1 - 0.12 11.5 0.4 0.13 11.4 0.4 1.0 1 0 0 1 1 1 0 Plant mobile domain PH PF00169.29 GAM16865.1 - 0.0025 18.3 0.0 0.0061 17.0 0.0 1.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 GAM16865.1 - 0.014 15.8 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain TFIIA PF03153.13 GAM16865.1 - 0.048 13.7 31.5 0.074 13.0 31.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ZZ PF00569.17 GAM16866.1 - 1.1e-08 34.8 5.9 1.9e-08 34.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 GAM16866.1 - 1.2e-07 31.8 0.0 2.5e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2HE PF16278.5 GAM16866.1 - 0.016 15.7 0.8 0.037 14.5 0.8 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Selenoprotein_S PF06936.11 GAM16866.1 - 3 7.6 5.4 4.4 7.1 5.4 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Tnp_zf-ribbon_2 PF13842.6 GAM16866.1 - 9.6 7.1 7.5 16 6.4 7.5 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DIM1 PF02966.16 GAM16867.1 - 7.7e-66 219.9 0.1 8.8e-66 219.7 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 GAM16867.1 - 0.0017 18.3 0.1 0.0024 17.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Spt20 PF12090.8 GAM16869.1 - 0.92 9.1 12.6 1.2 8.7 12.6 1.1 1 0 0 1 1 1 0 Spt20 family Strumpellin PF10266.9 GAM16870.1 - 0 1503.8 20.6 0 1503.7 20.6 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin DS PF01916.17 GAM16870.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Deoxyhypusine synthase Pox_MCEL PF03291.16 GAM16871.1 - 9e-40 136.8 0.6 2e-39 135.6 0.6 1.5 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 GAM16871.1 - 1.8e-09 38.2 0.0 3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM16871.1 - 2.5e-08 33.8 0.0 5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM16871.1 - 1.5e-06 28.8 0.0 3e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM16871.1 - 3.3e-05 24.5 0.0 5.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM16871.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain HOOK PF05622.12 GAM16872.1 - 3.1e-44 151.3 102.3 1.9e-42 145.3 102.3 3.0 1 1 0 1 1 1 1 HOOK protein DUF4407 PF14362.6 GAM16872.1 - 1.3 8.3 64.3 0.17 11.2 20.4 4.3 1 1 3 5 5 5 0 Domain of unknown function (DUF4407) PIP5K PF01504.18 GAM16875.1 - 2.4e-25 89.3 12.5 2.4e-25 89.3 12.5 3.9 2 2 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase SWIB PF02201.18 GAM16876.1 - 5.3e-18 64.7 0.8 5.3e-18 64.7 0.8 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain EF-hand_7 PF13499.6 GAM16877.1 - 0.00056 20.3 1.2 0.32 11.5 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM16877.1 - 0.0034 17.2 0.0 0.018 14.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GAM16877.1 - 0.0094 15.4 0.6 0.052 13.1 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 GAM16877.1 - 0.14 12.5 0.9 10 6.5 0.0 3.3 2 1 1 3 3 3 0 EF-hand domain GST_N_4 PF17172.4 GAM16878.1 - 1e-18 67.9 0.0 2.4e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GAM16878.1 - 1.7e-16 59.8 0.0 3.5e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM16878.1 - 1.5e-11 44.2 0.0 2.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM16878.1 - 2e-07 31.3 0.0 1.3e-06 28.7 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 GAM16878.1 - 1.4e-06 28.6 0.0 3.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 GAM16878.1 - 2.6e-06 27.5 0.0 4.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM16878.1 - 3.3e-06 27.2 0.0 5.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAM16878.1 - 0.025 15.1 0.0 0.045 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4119 PF13494.6 GAM16878.1 - 0.026 14.6 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) GST_N_2 PF13409.6 GAM16878.1 - 0.041 14.2 0.1 0.72 10.2 0.1 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.13 GAM16878.1 - 0.045 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain RRM_1 PF00076.22 GAM16879.1 - 6e-38 128.5 0.2 1.5e-15 56.7 0.1 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 GAM16879.1 - 1.8e-11 45.0 0.3 7.9e-11 42.9 0.0 2.2 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.6 GAM16879.1 - 9.6e-07 28.7 0.3 0.2 11.7 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAM16879.1 - 4.4e-05 23.5 0.1 1.1 9.4 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 GAM16879.1 - 0.0027 17.3 0.0 0.079 12.6 0.0 2.7 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 GAM16879.1 - 0.01 15.8 0.1 2.5 8.1 0.0 3.1 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 GAM16879.1 - 0.033 14.0 0.0 1.4 8.8 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif BAR_3 PF16746.5 GAM16880.1 - 6.4e-08 32.6 13.0 6.4e-08 32.6 13.0 1.8 2 0 0 2 2 2 1 BAR domain of APPL family RasGAP PF00616.19 GAM16880.1 - 0.0064 16.2 2.6 2.6 7.7 0.0 3.1 2 2 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase SMC_ScpB PF04079.16 GAM16880.1 - 0.019 14.6 0.4 0.059 13.0 0.4 1.8 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Pkinase PF00069.25 GAM16881.1 - 3e-75 253.0 0.0 4.7e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM16881.1 - 2.7e-47 161.3 0.0 4e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM16881.1 - 1.7e-07 30.9 0.0 1.2e-05 24.8 0.0 2.3 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 GAM16881.1 - 0.00039 20.4 0.0 0.054 13.4 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM16881.1 - 0.00046 19.6 0.9 0.0044 16.4 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM16881.1 - 0.00096 18.0 0.0 0.002 16.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 GAM16881.1 - 0.051 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ADP_ribosyl_GH PF03747.14 GAM16882.1 - 4.5e-47 161.2 0.0 5.3e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase PX PF00787.24 GAM16883.1 - 2.2e-11 43.7 0.5 2.2e-11 43.7 0.5 1.9 2 0 0 2 2 2 1 PX domain CUE PF02845.16 GAM16883.1 - 0.036 13.8 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 CUE domain SOG2 PF10428.9 GAM16883.1 - 8.2 5.5 29.1 0.22 10.7 21.1 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Kelch_6 PF13964.6 GAM16884.1 - 4.4e-13 49.0 5.6 0.028 14.7 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GAM16884.1 - 9e-10 38.4 5.5 0.0038 17.2 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM16884.1 - 1.5e-09 37.3 2.0 0.2 11.3 0.0 5.7 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 GAM16884.1 - 6.9e-08 32.6 14.6 0.073 13.4 0.0 6.0 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM16884.1 - 0.00087 19.2 0.7 13 5.9 0.0 4.5 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 GAM16884.1 - 0.001 19.0 2.7 8.1 6.6 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Serglycin PF04360.12 GAM16884.1 - 0.48 10.4 4.5 1 9.3 4.5 1.5 1 0 0 1 1 1 0 Serglycin Ank_2 PF12796.7 GAM16885.1 - 1e-114 375.3 31.5 3e-16 59.8 0.3 11.2 4 3 8 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM16885.1 - 4.3e-104 339.6 26.4 2.8e-11 43.7 0.3 16.5 6 4 10 16 16 16 16 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM16885.1 - 1.2e-92 302.7 33.3 9.3e-12 45.0 0.0 15.8 7 4 8 16 16 16 14 Ankyrin repeats (many copies) Ank PF00023.30 GAM16885.1 - 3e-82 267.7 39.9 5e-05 23.6 0.0 19.3 19 0 0 19 19 19 17 Ankyrin repeat Ank_3 PF13606.6 GAM16885.1 - 1.9e-78 248.9 30.9 8e-06 25.8 0.1 19.7 20 0 0 20 20 20 18 Ankyrin repeat IPK PF03770.16 GAM16886.1 - 3e-54 183.9 0.1 5.5e-54 183.0 0.1 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Tim17 PF02466.19 GAM16887.1 - 3e-27 95.2 7.2 4.1e-27 94.7 7.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 GAM16887.1 - 9.7 6.0 17.1 0.93 9.3 0.4 2.6 3 0 0 3 3 3 0 YMGG-like Gly-zipper LRR_6 PF13516.6 GAM16888.1 - 5.3e-23 79.1 39.3 0.00023 21.0 1.3 9.4 10 0 0 10 10 10 8 Leucine Rich repeat LRR_4 PF12799.7 GAM16888.1 - 0.08 13.4 33.9 2.1 8.9 0.0 6.8 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM16888.1 - 1.1 10.0 17.3 1.4e+02 3.7 0.1 8.1 7 2 0 7 7 7 0 Leucine Rich Repeat DUF229 PF02995.17 GAM16889.1 - 2.9e-38 131.7 0.2 7.2e-38 130.4 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 GAM16889.1 - 0.00055 19.4 0.0 0.063 12.7 0.0 2.4 1 1 1 2 2 2 2 Sulfatase DUF3899 PF13038.6 GAM16889.1 - 0.0063 17.0 1.8 0.0063 17.0 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3899) DUF3341 PF11821.8 GAM16889.1 - 0.14 11.8 1.0 0.44 10.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) DUF4293 PF14126.6 GAM16889.1 - 0.66 10.2 6.2 1.7 8.8 6.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) CO_dh PF02552.16 GAM16889.1 - 0.93 9.3 2.6 0.82 9.4 0.1 2.1 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Ufd2P_core PF10408.9 GAM16890.1 - 2.9e-190 634.0 17.5 5.1e-190 633.2 17.5 1.4 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 GAM16890.1 - 1.1e-28 99.2 2.6 2.3e-28 98.2 1.4 2.3 2 0 0 2 2 2 1 U-box domain DUF3439 PF11921.8 GAM16890.1 - 9.3e-05 22.4 2.5 0.00023 21.1 2.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SUIM_assoc PF16619.5 GAM16890.1 - 0.0022 18.0 6.3 0.0098 15.9 6.3 2.2 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GAM16890.1 - 0.028 14.1 11.9 0.067 12.8 11.9 1.6 1 0 0 1 1 1 0 Spt20 family DUF3364 PF11844.8 GAM16890.1 - 0.18 12.1 0.0 0.18 12.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) NUDE_C PF04880.13 GAM16890.1 - 0.31 11.5 7.2 0.66 10.4 7.2 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Mucin PF01456.17 GAM16890.1 - 1.4 8.9 18.5 2.9 7.9 18.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF846 PF05832.12 GAM16891.1 - 0.01 15.9 3.7 0.091 12.8 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF846) DUF2070 PF09843.9 GAM16891.1 - 0.68 8.2 7.6 0.99 7.6 7.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YabA PF06156.13 GAM16892.1 - 0.039 14.6 1.1 0.039 14.6 1.1 4.2 2 1 0 2 2 2 0 Initiation control protein YabA RhoGAP PF00620.27 GAM16893.1 - 9.6e-40 135.9 1.8 4.4e-39 133.7 0.2 2.3 2 0 0 2 2 2 1 RhoGAP domain Ribosomal_S7 PF00177.21 GAM16894.1 - 2.2e-34 118.3 0.8 2.7e-34 118.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RhoGEF PF00621.20 GAM16896.1 - 1.4e-41 142.8 0.5 3.4e-41 141.5 0.5 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAM16896.1 - 9.4e-06 26.1 0.1 0.0011 19.4 0.1 3.0 1 1 0 1 1 1 1 PH domain PH_13 PF16652.5 GAM16896.1 - 0.00035 20.4 0.0 0.57 10.0 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 GAM16896.1 - 0.015 15.5 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_10 PF15411.6 GAM16896.1 - 0.025 14.9 0.0 0.025 14.9 0.0 2.4 3 0 0 3 3 3 0 Pleckstrin homology domain IQ PF00612.27 GAM16896.1 - 0.12 12.2 1.2 0.27 11.1 1.2 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF2052 PF09747.9 GAM16896.1 - 0.48 10.5 7.1 0.86 9.7 7.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) K_channel_TID PF07941.11 GAM16896.1 - 4.2 7.9 6.8 7.5 7.1 0.4 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Ribosomal_60s PF00428.19 GAM16896.1 - 4.6 7.9 9.2 7.4 7.2 6.1 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Med24_N PF11277.8 GAM16898.1 - 2.1e-08 32.8 0.1 2.1e-08 32.8 0.1 2.7 2 1 0 2 2 2 1 Mediator complex subunit 24 N-terminal TFIIA PF03153.13 GAM16899.1 - 0.097 12.7 24.9 0.16 12.0 24.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C1 PF00112.23 GAM16900.1 - 1.4e-54 185.4 4.4 1.9e-54 185.1 4.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAM16900.1 - 0.051 12.4 0.4 0.051 12.4 0.4 1.9 3 0 0 3 3 3 0 Peptidase C1-like family DOMON PF03351.17 GAM16901.1 - 6.8e-14 52.2 0.0 1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 GAM16901.1 - 3.6e-09 36.9 14.3 3.6e-09 36.9 14.3 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 GAM16901.1 - 0.013 15.3 9.2 0.38 10.6 8.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) UQ_con PF00179.26 GAM16902.1 - 7.4e-49 165.0 0.0 8.1e-49 164.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM16902.1 - 1.9e-06 27.6 0.0 2.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B bZIP_1 PF00170.21 GAM16903.1 - 5.7e-09 35.9 18.0 2.1e-08 34.1 9.3 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 GAM16903.1 - 5.5e-05 23.2 17.4 0.0002 21.3 8.7 2.5 2 0 0 2 2 2 2 Basic region leucine zipper HAUS-augmin3 PF14932.6 GAM16903.1 - 0.0057 16.3 8.7 0.0057 16.3 8.7 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 KASH_CCD PF14662.6 GAM16903.1 - 0.029 14.2 14.2 0.05 13.4 14.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF5632 PF18646.1 GAM16903.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5632) HTH_1 PF00126.27 GAM16903.1 - 0.071 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Sulfotransfer_4 PF17784.1 GAM16903.1 - 0.11 12.4 0.1 0.11 12.4 0.1 1.5 2 0 0 2 2 2 0 Sulfotransferase domain SelP_N PF04592.14 GAM16903.1 - 1.9 7.9 15.1 4.8 6.5 15.1 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF812 PF05667.11 GAM16903.1 - 4.8 5.9 15.0 0.5 9.2 10.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Presenilin PF01080.17 GAM16905.1 - 0.02 13.7 6.6 0.024 13.4 6.6 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 GAM16905.1 - 0.02 13.7 2.7 0.024 13.4 2.7 1.1 1 0 0 1 1 1 0 Raftlin Med3 PF11593.8 GAM16905.1 - 0.025 13.8 12.0 0.032 13.4 12.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Plasmodium_Vir PF05795.11 GAM16905.1 - 0.033 13.6 6.4 0.044 13.2 6.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Band_3_cyto PF07565.13 GAM16905.1 - 0.061 13.1 2.5 0.088 12.6 2.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.13 GAM16905.1 - 0.096 13.3 8.4 0.15 12.7 8.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.16 GAM16905.1 - 0.15 12.1 1.5 0.21 11.6 1.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF5523 PF17661.1 GAM16905.1 - 0.23 11.1 8.7 0.33 10.6 8.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Ndc1_Nup PF09531.10 GAM16905.1 - 0.46 9.1 9.1 0.58 8.8 9.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tim54 PF11711.8 GAM16905.1 - 0.7 8.6 6.2 1 8.1 6.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 GAM16905.1 - 0.77 9.5 9.6 1.1 9.1 9.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cytomega_UL20A PF05984.12 GAM16905.1 - 0.82 10.0 10.4 1.4 9.3 10.4 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein CCDC106 PF15794.5 GAM16905.1 - 2.3 7.9 8.7 3.5 7.3 8.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 AIF_C PF14721.6 GAM16905.1 - 2.6 8.4 6.7 6.1 7.2 6.7 1.6 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF908 PF06012.12 GAM16905.1 - 3.3 7.0 17.5 4.1 6.7 17.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF3464 PF11947.8 GAM16905.1 - 3.5 7.4 5.7 7.6 6.3 5.8 1.6 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 V_ATPase_I PF01496.19 GAM16905.1 - 4.2 5.2 6.9 5.6 4.8 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hamartin PF04388.12 GAM16905.1 - 5.4 5.5 11.1 6.9 5.2 11.1 1.1 1 0 0 1 1 1 0 Hamartin protein SCHIP-1 PF10148.9 GAM16905.1 - 5.6 6.5 7.1 8 6.0 7.1 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 CDC45 PF02724.14 GAM16905.1 - 6.9 4.8 7.2 8.9 4.5 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 GAM16905.1 - 7.5 6.4 13.7 9.7 6.0 13.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Med13_C PF06333.12 GAM16905.1 - 9.9 5.3 12.3 13 4.9 12.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Spt20 PF12090.8 GAM16907.1 - 0.00077 19.1 44.5 0.16 11.6 1.9 3.3 3 0 0 3 3 3 3 Spt20 family DUF4720 PF15846.5 GAM16907.1 - 0.03 14.2 0.0 0.16 11.8 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) EPL1 PF10513.9 GAM16907.1 - 3.2 8.1 22.9 0.57 10.5 8.2 3.1 3 0 0 3 3 3 0 Enhancer of polycomb-like RNase_HII PF01351.18 GAM16908.1 - 3.1e-38 131.6 9.7 5.4e-21 75.3 0.2 3.2 3 1 1 4 4 4 2 Ribonuclease HII RskA PF10099.9 GAM16908.1 - 0.26 11.6 10.6 0.12 12.7 7.5 2.1 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Abhydro_lipase PF04083.16 GAM16909.1 - 1.7e-19 69.1 0.0 3.5e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 GAM16909.1 - 5.1e-16 59.1 0.1 3.2e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM16909.1 - 0.047 13.0 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SRF-TF PF00319.18 GAM16911.1 - 8.8e-19 66.7 0.2 1.5e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Suf PF05843.14 GAM16911.1 - 0.38 10.7 18.3 1 9.2 18.3 1.8 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 GAM16911.1 - 0.77 9.7 16.2 0.98 9.3 16.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 GAM16911.1 - 2.1 5.4 19.6 3.3 4.7 19.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer I_LWEQ PF01608.17 GAM16912.1 - 1.3e-61 207.3 196.6 4.7e-47 160.1 11.3 19.5 5 3 11 20 20 20 15 I/LWEQ domain FERM_f0 PF16511.5 GAM16912.1 - 5.3e-30 103.6 0.1 1.1e-25 89.7 0.0 3.4 3 0 0 3 3 3 2 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 GAM16912.1 - 8.7e-28 97.1 0.4 8e-27 94.0 0.0 3.0 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 GAM16912.1 - 3.8e-15 55.6 0.1 1.3e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain VHP PF02209.19 GAM16912.1 - 3.6e-14 52.5 1.1 3.6e-14 52.5 1.1 2.1 2 0 0 2 2 2 1 Villin headpiece domain VBS PF08913.10 GAM16912.1 - 0.0002 21.8 16.0 0.00039 20.9 6.8 13.6 11 2 1 14 14 14 5 Vinculin Binding Site Chibby PF14645.6 GAM16913.1 - 3.7e-07 30.5 1.6 6.1e-07 29.9 1.6 1.3 1 0 0 1 1 1 1 Chibby family JAKMIP_CC3 PF16034.5 GAM16913.1 - 0.0059 16.6 0.9 0.0094 15.9 0.9 1.3 1 0 0 1 1 1 1 JAKMIP CC3 domain Phage_lysis PF03245.13 GAM16913.1 - 0.086 13.0 1.1 0.11 12.7 1.1 1.1 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Imm7 PF15585.6 GAM16913.1 - 0.087 13.1 0.0 0.097 13.0 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 7 zf-CCCH_6 PF18585.1 GAM16913.1 - 0.12 12.3 2.0 0.54 10.2 1.2 2.4 1 1 1 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 FapA PF03961.13 GAM16914.1 - 0.22 10.1 4.9 0.29 9.7 4.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pkinase PF00069.25 GAM16915.1 - 3.2e-80 269.3 0.0 3.6e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM16915.1 - 2.8e-34 118.6 0.0 3.5e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM16915.1 - 0.00038 19.5 0.0 0.0059 15.6 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 GAM16915.1 - 0.003 16.7 0.0 0.3 10.1 0.0 2.1 2 0 0 2 2 2 2 Seadornavirus VP7 Kinase-like PF14531.6 GAM16915.1 - 0.01 15.1 0.0 0.05 12.9 0.0 1.9 1 1 0 2 2 2 0 Kinase-like APH PF01636.23 GAM16915.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAM16915.1 - 0.11 11.9 0.2 0.24 10.8 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sporozoite_P67 PF05642.11 GAM16916.1 - 0.45 8.5 10.3 0.46 8.5 10.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen KAR9 PF08580.10 GAM16916.1 - 1.9 6.9 12.8 2.3 6.6 12.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Myb_DNA-binding PF00249.31 GAM16917.1 - 2.7e-44 149.1 16.8 1.5e-15 57.1 2.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM16917.1 - 3.4e-37 126.5 12.8 7.5e-17 61.3 2.0 4.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 GAM16917.1 - 0.00011 22.3 2.8 0.27 11.3 0.2 3.9 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 GAM16917.1 - 0.0034 17.4 9.3 0.47 10.5 0.0 4.2 3 1 2 5 5 5 2 SLIDE Myb_DNA-bind_2 PF08914.11 GAM16917.1 - 0.058 13.6 0.0 6.5 7.0 0.0 3.3 3 0 0 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 GAM16917.1 - 0.062 13.2 0.1 0.062 13.2 0.1 3.3 3 2 0 3 3 3 0 Myb DNA-binding like Rubella_E2 PF05749.11 GAM16917.1 - 0.074 12.5 0.7 0.19 11.2 0.7 1.6 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Sigma70_r4_2 PF08281.12 GAM16917.1 - 0.16 11.6 0.0 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 MADF_DNA_bdg PF10545.9 GAM16917.1 - 0.23 11.8 5.5 19 5.6 0.3 3.8 1 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3439 PF11921.8 GAM16917.1 - 8.8 6.3 11.6 11 6.0 7.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) LRR_6 PF13516.6 GAM16918.1 - 1.5e-16 58.9 23.2 0.019 15.0 0.0 10.0 10 0 0 10 10 10 4 Leucine Rich repeat Carm_PH PF17888.1 GAM16918.1 - 0.014 15.7 0.2 0.041 14.2 0.2 1.8 1 0 0 1 1 1 0 Carmil pleckstrin homology domain LRR_4 PF12799.7 GAM16918.1 - 0.042 14.3 25.2 1.3 9.6 0.4 6.2 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) Herpes_UL36 PF03586.13 GAM16918.1 - 0.24 10.7 0.7 0.5 9.6 0.7 1.5 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein LRR_1 PF00560.33 GAM16918.1 - 2.4 9.0 21.0 50 5.0 0.2 9.5 10 1 0 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.6 GAM16918.1 - 2.9 7.7 27.8 1.6 8.5 0.5 6.1 6 1 1 7 7 7 0 Leucine rich repeat ATG27 PF09451.10 GAM16919.1 - 3.6e-07 30.3 1.7 1.5e-06 28.3 1.7 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 GAM16919.1 - 4.2e-06 26.9 2.2 3e-05 24.1 0.3 2.1 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 GAM16919.1 - 0.0023 17.6 0.1 0.0037 17.0 0.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Pkinase_Tyr PF07714.17 GAM16920.1 - 7.9e-55 185.9 0.0 1.3e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM16920.1 - 1e-48 166.0 0.0 2.6e-48 164.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 GAM16920.1 - 3.3e-11 43.1 0.0 9.4e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 GAM16920.1 - 2.4e-05 24.1 0.0 6.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 GAM16920.1 - 8.6e-05 23.2 0.0 0.00024 21.7 0.0 1.8 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Mso1_C PF14477.6 GAM16920.1 - 0.0067 16.8 0.6 0.0067 16.8 0.6 2.4 1 1 1 2 2 2 1 Membrane-polarising domain of Mso1 SH2_2 PF14633.6 GAM16920.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 SH2 domain APH PF01636.23 GAM16920.1 - 0.041 13.8 0.1 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family IBP39 PF11422.8 GAM16920.1 - 0.054 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Initiator binding protein 39 kDa HABP4_PAI-RBP1 PF04774.15 GAM16922.1 - 5.7e-13 49.7 5.4 5.7e-13 49.7 5.4 4.1 2 2 1 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 GAM16922.1 - 9.3e-06 26.4 9.2 9.3e-06 26.4 9.2 4.7 3 2 1 4 4 4 1 Stm1 WD40 PF00400.32 GAM16923.1 - 4.2e-21 74.8 13.8 5.4e-07 30.2 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM16923.1 - 0.00027 21.2 0.0 0.15 12.4 0.0 3.6 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BUD22 PF09073.10 GAM16923.1 - 0.0043 16.5 14.5 0.0067 15.8 14.5 1.4 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 GAM16923.1 - 0.0078 15.7 17.7 0.012 15.0 17.7 1.4 1 0 0 1 1 1 1 SDA1 BBS2_Mid PF14783.6 GAM16923.1 - 0.017 15.1 0.0 1.1 9.3 0.0 3.4 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PPP4R2 PF09184.11 GAM16923.1 - 5.6 6.5 20.9 11 5.5 20.9 1.5 1 0 0 1 1 1 0 PPP4R2 DUF2721 PF11026.8 GAM16925.1 - 0.039 13.8 0.2 0.054 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) UbiA PF01040.18 GAM16925.1 - 0.05 12.9 3.6 0.11 11.8 3.6 1.5 1 1 0 1 1 1 0 UbiA prenyltransferase family Sarcoglycan_2 PF05510.13 GAM16925.1 - 0.071 11.9 0.0 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF872 PF05915.12 GAM16925.1 - 0.28 11.3 5.4 2.8 8.1 5.4 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF3377 PF11857.8 GAM16925.1 - 0.36 10.8 1.3 4.4 7.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3377) DUF3040 PF11239.8 GAM16925.1 - 2.3 8.6 5.4 4.5 7.6 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF308 PF03729.13 GAM16925.1 - 4.1 7.8 9.7 7.8 6.9 6.8 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) TatD_DNase PF01026.21 GAM16927.1 - 8.4e-48 163.0 0.0 1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase PI3_PI4_kinase PF00454.27 GAM16928.1 - 3e-37 128.8 4.8 2.1e-33 116.2 0.2 4.1 3 1 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAM16928.1 - 0.0018 17.7 0.3 0.005 16.3 0.3 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) FNIP PF05725.12 GAM16929.1 - 2.3e-85 280.5 35.2 4.4e-14 52.4 0.0 9.6 6 3 3 10 10 10 10 FNIP Repeat DUF1769 PF08588.10 GAM16929.1 - 0.0028 17.8 0.9 4.8 7.5 0.0 4.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1769) Glyco_hydro_65C PF03633.15 GAM16929.1 - 0.16 11.9 0.6 75 3.4 0.0 4.4 6 0 0 6 6 6 0 Glycosyl hydrolase family 65, C-terminal domain Cofilin_ADF PF00241.20 GAM16930.1 - 1.7e-25 89.2 0.0 1.9e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DHHC PF01529.20 GAM16931.1 - 7.5e-31 107.0 23.9 7.5e-31 107.0 23.9 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase CDP-OH_P_transf PF01066.21 GAM16932.1 - 4.1e-16 59.5 0.1 4.1e-16 59.5 0.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase F-box PF00646.33 GAM16933.1 - 0.019 14.8 0.3 0.063 13.2 0.3 1.9 1 0 0 1 1 1 0 F-box domain TPP1 PF10341.9 GAM16934.1 - 0.085 12.8 0.0 0.085 12.8 0.0 2.7 4 0 0 4 4 4 0 Shelterin complex subunit, TPP1/ACD Sortilin-Vps10 PF15902.5 GAM16935.1 - 1.1e-59 202.5 0.9 1.3e-59 202.2 0.9 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 GAM16935.1 - 2.6e-19 70.2 0.0 3.8e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 GAM16935.1 - 0.0072 16.1 16.6 14 6.2 0.0 7.5 7 0 0 7 7 7 3 BNR/Asp-box repeat 4HBT PF03061.22 GAM16936.1 - 2.6e-12 46.9 0.0 4.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 GAM16936.1 - 0.082 13.1 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Aminotran_4 PF01063.19 GAM16937.1 - 1.2e-35 123.5 0.0 1.5e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Methyltransf_11 PF08241.12 GAM16938.1 - 2e-16 60.4 0.0 3.1e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM16938.1 - 1.8e-13 51.0 0.0 6.6e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM16938.1 - 1.4e-11 44.4 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM16938.1 - 3e-07 31.1 0.0 3e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM16938.1 - 5.4e-06 25.9 0.1 1.1e-05 24.9 0.1 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 GAM16938.1 - 0.00012 21.8 0.0 0.00029 20.6 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Sigma70_ner PF04546.13 GAM16938.1 - 0.0002 21.3 5.3 0.00029 20.8 5.3 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region PrmA PF06325.13 GAM16938.1 - 0.0035 16.8 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAM16938.1 - 0.0043 16.6 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Usp PF00582.26 GAM16938.1 - 0.068 13.7 1.0 0.093 13.2 1.0 1.2 1 0 0 1 1 1 0 Universal stress protein family PPP4R2 PF09184.11 GAM16938.1 - 0.3 10.7 14.5 0.41 10.2 14.5 1.2 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 GAM16938.1 - 0.43 8.6 27.4 0.49 8.4 27.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GAM16938.1 - 0.68 9.3 19.8 0.83 9.0 19.8 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 GAM16938.1 - 1 8.6 25.3 1.6 8.0 25.3 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 GAM16938.1 - 1.9 8.5 13.7 3.4 7.7 13.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Astro_capsid_p PF12226.8 GAM16938.1 - 3.3 6.8 16.2 4.1 6.5 16.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein VCBS PF13517.6 GAM16939.1 - 2.2e-32 111.4 27.4 1.1e-11 45.1 2.6 6.1 3 2 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 GAM16939.1 - 6.1e-15 54.9 0.0 1.1e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 GAM16939.1 - 4.6e-14 52.2 26.7 0.0059 16.7 0.0 8.0 9 0 0 9 9 9 6 FG-GAP repeat Herpes_UL6 PF01763.16 GAM16939.1 - 0.002 16.8 0.6 0.0029 16.2 0.6 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like RabGAP-TBC PF00566.18 GAM16940.1 - 8.8e-33 113.8 0.2 1.5e-32 113.0 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 GAM16940.1 - 2.2e-30 105.9 0.0 3.9e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM16940.1 - 1.8e-18 66.7 0.0 3.7e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 GAM16940.1 - 0.00014 22.3 0.0 0.0012 19.4 0.0 2.5 2 1 0 2 2 2 1 Rhodanese-like domain Haspin_kinase PF12330.8 GAM16940.1 - 0.043 12.8 5.8 0.049 12.6 0.2 2.3 1 1 1 2 2 2 0 Haspin like kinase domain SprA-related PF12118.8 GAM16940.1 - 2.9 6.9 4.7 5.1 6.1 4.7 1.3 1 0 0 1 1 1 0 SprA-related family FNIP PF05725.12 GAM16941.1 - 6e-61 202.4 13.8 1.2e-12 47.8 0.0 7.8 3 2 3 8 8 8 8 FNIP Repeat Glyco_hydro_65C PF03633.15 GAM16941.1 - 0.0017 18.2 0.6 87 3.1 0.0 6.4 7 0 0 7 7 7 1 Glycosyl hydrolase family 65, C-terminal domain EF-hand_1 PF00036.32 GAM16942.1 - 4.8e-23 78.9 0.4 4e-05 22.9 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 GAM16942.1 - 1.2e-20 71.5 1.4 0.00011 21.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 GAM16942.1 - 2.2e-20 72.9 0.5 2.2e-09 37.6 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM16942.1 - 2.9e-15 55.0 0.2 0.0011 18.3 0.1 4.7 4 1 1 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 GAM16942.1 - 2.1e-11 44.1 0.3 1.1e-05 25.7 0.1 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 GAM16942.1 - 3e-11 43.0 2.7 0.00014 21.6 0.4 4.2 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 GAM16942.1 - 6.5e-06 26.4 0.3 0.014 15.7 0.0 3.6 2 1 2 4 4 4 1 EF-hand domain Dockerin_1 PF00404.18 GAM16942.1 - 7.4e-05 22.9 0.1 0.029 14.6 0.0 2.3 2 0 0 2 2 2 2 Dockerin type I domain EF-hand_4 PF12763.7 GAM16942.1 - 8.8e-05 22.4 0.4 0.0025 17.7 0.1 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 GAM16942.1 - 0.00017 21.4 3.5 1.8 8.5 0.0 3.5 1 1 2 3 3 3 2 EF hand EF-hand_11 PF08976.11 GAM16942.1 - 0.0066 17.3 0.0 0.03 15.2 0.0 1.9 1 1 0 2 2 2 1 EF-hand domain SecA_DEAD PF07517.14 GAM16943.1 - 5.9e-08 32.4 0.0 2.2e-07 30.5 0.0 2.1 1 0 0 1 1 1 1 SecA DEAD-like domain MMR_HSR1 PF01926.23 GAM16943.1 - 1.9e-05 24.7 0.3 0.00013 22.0 0.3 2.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM16943.1 - 0.00019 21.4 0.3 0.00074 19.5 0.3 2.1 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 GAM16943.1 - 0.0026 18.3 0.9 0.034 14.7 0.3 3.4 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 GAM16943.1 - 0.0031 17.8 0.1 0.12 12.6 0.1 3.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 GAM16943.1 - 0.0037 17.6 0.0 0.022 15.2 0.0 2.5 1 0 0 1 1 1 1 RNA helicase Apo-CIII PF05778.12 GAM16943.1 - 0.027 14.1 0.1 0.63 9.7 0.0 3.2 3 0 0 3 3 3 0 Apolipoprotein CIII (Apo-CIII) PduV-EutP PF10662.9 GAM16943.1 - 0.029 14.1 0.2 0.18 11.6 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.23 GAM16943.1 - 0.1 12.6 0.9 33 4.5 0.0 4.2 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain FokI_N PF02981.15 GAM16943.1 - 0.14 12.3 0.5 1.6 8.9 0.1 2.9 3 0 0 3 3 3 0 Restriction endonuclease FokI, recognition domain AAA_29 PF13555.6 GAM16943.1 - 0.15 11.8 0.5 0.48 10.2 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4335 PF14233.6 GAM16943.1 - 0.32 10.9 1.9 1.5 8.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4335) Helicase_C PF00271.31 GAM16943.1 - 0.92 9.9 4.7 2.4 8.5 0.1 4.0 3 0 0 3 3 2 0 Helicase conserved C-terminal domain DUF1515 PF07439.11 GAM16944.1 - 0.1 12.6 1.2 2.9 8.0 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF3450 PF11932.8 GAM16944.1 - 1.7 7.8 5.5 1.8 7.8 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) BCDHK_Adom3 PF10436.9 GAM16944.1 - 2.6 7.9 8.5 2.9 7.7 0.5 3.5 3 3 0 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase RNA_polI_A34 PF08208.11 GAM16945.1 - 0.00023 21.4 11.5 0.00029 21.0 11.5 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 CDC27 PF09507.10 GAM16945.1 - 0.00079 18.9 20.3 0.001 18.6 20.3 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Nop14 PF04147.12 GAM16945.1 - 0.002 16.4 9.2 0.0021 16.4 9.2 1.2 1 0 0 1 1 1 1 Nop14-like family 2OG-FeII_Oxy_5 PF13759.6 GAM16945.1 - 0.12 12.7 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase SDA1 PF05285.12 GAM16945.1 - 0.17 11.3 19.2 0.21 11.0 19.2 1.1 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 GAM16945.1 - 0.3 10.9 9.5 0.38 10.6 9.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GAM16945.1 - 0.37 9.0 17.2 0.44 8.8 17.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.13 GAM16945.1 - 0.59 8.4 7.2 0.7 8.2 7.2 1.1 1 0 0 1 1 1 0 Menin RRN3 PF05327.11 GAM16945.1 - 5.3 5.5 10.0 7.4 5.0 10.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.15 GAM16945.1 - 5.5 5.7 14.5 7 5.3 14.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GAM16945.1 - 8.4 5.0 9.9 10 4.8 9.9 1.1 1 0 0 1 1 1 0 Presenilin BclA_C PF18573.1 GAM16946.1 - 0.17 11.8 5.7 0.13 12.2 4.3 1.5 1 1 1 2 2 2 0 BclA C-terminal domain SecA_DEAD PF07517.14 GAM16947.1 - 1.9e-08 33.9 0.0 7e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 SecA DEAD-like domain Hfq PF17209.3 GAM16947.1 - 0.037 13.7 1.0 0.45 10.2 0.0 3.1 3 0 0 3 3 3 0 Hfq protein CbiA PF01656.23 GAM16947.1 - 0.13 12.3 0.2 25 5.0 0.0 3.7 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Endotoxin_N PF03945.14 GAM16948.1 - 6.1e-29 101.3 0.1 1e-28 100.6 0.1 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Anophelin PF10731.9 GAM16948.1 - 0.12 12.3 0.5 10 6.1 0.2 2.5 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Endotoxin_N PF03945.14 GAM16949.1 - 3e-19 69.6 0.2 5e-19 68.9 0.2 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.14 GAM16950.1 - 1.3e-32 113.3 0.0 2e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain DUF2066 PF09839.9 GAM16950.1 - 0.21 10.9 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) Endotoxin_N PF03945.14 GAM16951.1 - 1.3e-27 96.9 0.0 1.6e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.14 GAM16953.1 - 4.3e-28 98.6 0.0 6.9e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Ribosomal_L32p PF01783.23 GAM16954.1 - 1.2e-10 41.5 11.9 1.5e-10 41.2 11.9 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.7 GAM16954.1 - 0.053 13.6 1.3 0.083 12.9 1.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon Acetone_carb_G PF08882.11 GAM16954.1 - 0.073 13.2 0.6 0.087 13.0 0.6 1.1 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit Metallophos PF00149.28 GAM16955.1 - 5.7e-35 121.7 0.6 8.7e-35 121.1 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAM16955.1 - 0.00091 19.6 0.1 0.0018 18.7 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 GAM16955.1 - 0.052 13.2 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 GAM16955.1 - 0.098 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Exo70 PF03081.15 GAM16956.1 - 2.4e-38 132.2 9.2 2.4e-38 132.2 9.2 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit DASH_Dad2 PF08654.10 GAM16956.1 - 0.00025 21.4 0.9 0.0011 19.4 0.5 2.4 1 1 0 1 1 1 1 DASH complex subunit Dad2 Sec34 PF04136.15 GAM16956.1 - 0.00065 19.6 2.6 0.00065 19.6 2.6 3.1 3 0 0 3 3 3 1 Sec34-like family DUF416 PF04222.12 GAM16956.1 - 0.0072 15.8 0.0 0.024 14.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF416) FNIP_C PF14638.6 GAM16956.1 - 0.045 13.4 0.9 0.1 12.2 0.9 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus Vps51 PF08700.11 GAM16956.1 - 0.31 11.2 4.3 1 9.5 0.1 4.0 5 0 0 5 5 5 0 Vps51/Vps67 Zip PF02535.22 GAM16957.1 - 5.5e-41 140.9 15.5 2.1e-40 139.0 15.5 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Far-17a_AIG1 PF04750.14 GAM16959.1 - 8.3e-29 100.3 14.3 1.8e-28 99.2 14.3 1.5 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein PDR_assoc PF08370.11 GAM16959.1 - 0.041 13.6 0.1 0.041 13.6 0.1 2.1 3 0 0 3 3 3 0 Plant PDR ABC transporter associated RNA_pol_Rpb1_5 PF04998.17 GAM16960.1 - 1.9e-88 296.4 3.0 5.7e-88 294.8 3.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAM16960.1 - 2.1e-58 197.2 0.0 5e-58 196.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 GAM16960.1 - 5.6e-32 111.3 2.2 2.3e-31 109.3 2.2 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 GAM16960.1 - 8.5e-32 110.3 0.0 2.8e-31 108.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAM16960.1 - 2.9e-23 81.9 0.0 2.9e-23 81.9 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 SDA1 PF05285.12 GAM16960.1 - 0.85 9.0 40.5 2 7.7 1.2 3.0 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 GAM16960.1 - 1.1 7.4 43.5 0.1 10.8 32.7 2.2 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 GAM16960.1 - 2.6 7.3 41.5 6.2 6.1 0.9 2.5 2 0 0 2 2 2 0 BUD22 TPR_17 PF13431.6 GAM16962.1 - 0.17 12.3 4.6 15 6.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat GRP PF07172.11 GAM16962.1 - 2.6 8.8 33.9 14 6.5 9.4 3.9 3 0 0 3 3 3 0 Glycine rich protein family FNIP PF05725.12 GAM16963.1 - 2e-33 114.3 12.4 5.8e-13 48.8 0.2 5.8 5 1 1 6 6 6 4 FNIP Repeat DUF1769 PF08588.10 GAM16963.1 - 0.014 15.6 3.4 3.8 7.8 0.0 4.5 2 1 3 5 5 5 0 Protein of unknown function (DUF1769) F-box-like PF12937.7 GAM16963.1 - 0.15 12.0 0.3 0.33 10.9 0.3 1.6 1 0 0 1 1 1 0 F-box-like Actin PF00022.19 GAM16964.1 - 5.4e-95 318.4 0.0 5.1e-94 315.2 0.0 1.9 1 1 0 1 1 1 1 Actin tRNA_U5-meth_tr PF05958.11 GAM16965.1 - 1.9e-18 66.6 0.1 4.7e-11 42.3 0.0 2.6 1 1 1 2 2 2 2 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.16 GAM16965.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein EzrA PF06160.12 GAM16966.1 - 0.011 14.0 21.3 0.015 13.5 21.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3461 PF11944.8 GAM16966.1 - 0.4 10.8 10.7 2.4 8.3 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) PAT1 PF09770.9 GAM16966.1 - 0.68 8.1 13.6 0.81 7.9 13.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CALCOCO1 PF07888.11 GAM16966.1 - 0.89 8.3 21.0 1.1 8.0 21.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Leu_zip PF15294.6 GAM16966.1 - 1.9 8.0 19.4 2.6 7.5 19.4 1.1 1 0 0 1 1 1 0 Leucine zipper TetR_C_23 PF17931.1 GAM16966.1 - 1.9 8.6 6.7 0.38 10.9 2.4 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain IFT57 PF10498.9 GAM16966.1 - 3.4 6.5 24.3 34 3.3 24.3 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 HisKA_3 PF07730.13 GAM16966.1 - 3.6 8.2 7.0 4.6 7.8 0.6 2.6 2 0 0 2 2 2 0 Histidine kinase YojJ PF10372.9 GAM16966.1 - 3.7 7.7 8.7 0.23 11.5 2.2 2.2 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus PRKG1_interact PF15898.5 GAM16966.1 - 4.7 8.2 23.1 3.6e+02 2.1 18.7 3.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3466 PF11949.8 GAM16967.1 - 0.03 13.0 0.3 0.053 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) G-alpha PF00503.20 GAM16968.1 - 7.5e-93 311.5 16.3 9.5e-93 311.2 16.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM16968.1 - 3.3e-14 52.7 1.0 2.5e-10 40.1 0.0 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAM16968.1 - 0.00034 20.8 3.7 0.091 13.0 0.0 2.9 3 0 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase Sds3 PF08598.11 GAM16968.1 - 0.0012 18.9 3.2 0.0012 18.9 3.2 2.1 2 0 0 2 2 2 1 Sds3-like Gtr1_RagA PF04670.12 GAM16968.1 - 0.0014 18.1 8.6 0.0018 17.7 0.1 3.2 3 1 0 4 4 4 1 Gtr1/RagA G protein conserved region DUF3439 PF11921.8 GAM16968.1 - 0.0025 17.7 6.8 0.0025 17.7 6.8 1.9 2 0 0 2 2 1 1 Domain of unknown function (DUF3439) MMR_HSR1 PF01926.23 GAM16968.1 - 0.038 14.1 2.3 1.9 8.6 0.1 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase Mucin PF01456.17 GAM16968.1 - 0.36 10.8 16.7 0.92 9.5 16.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein ALMT PF11744.8 GAM16968.1 - 0.4 9.5 10.8 0.25 10.2 3.3 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter POX PF07526.11 GAM16968.1 - 2.3 8.8 9.4 16 6.0 0.5 2.5 2 0 0 2 2 2 0 Associated with HOX Menin PF05053.13 GAM16968.1 - 5.6 5.2 20.3 2.3 6.5 5.8 2.1 2 0 0 2 2 2 0 Menin CCDC106 PF15794.5 GAM16968.1 - 9.7 5.8 15.7 2.1 8.0 7.8 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF2967 PF11179.8 GAM16969.1 - 3.6 5.6 10.2 3.8 5.5 10.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) WD40 PF00400.32 GAM16970.1 - 7.9e-16 58.2 10.0 0.0022 18.8 2.2 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.6 GAM16970.1 - 0.0016 18.1 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 PQQ-like domain BBS2_Mid PF14783.6 GAM16970.1 - 0.021 14.9 0.0 8.2 6.5 0.0 3.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 GAM16970.1 - 0.033 14.5 0.1 7.1 7.0 0.0 3.8 2 2 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Invas_SpaK PF03519.14 GAM16970.1 - 0.075 13.1 0.9 17 5.6 0.0 3.1 2 1 1 3 3 3 0 Invasion protein B family Inhibitor_I36 PF03995.13 GAM16970.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Peptidase inhibitor family I36 VASt PF16016.5 GAM16971.1 - 3.5e-35 121.7 2.7 9.7e-35 120.2 2.7 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GAM16971.1 - 4.6e-15 55.5 1.2 1.1e-14 54.2 0.3 2.1 2 0 0 2 2 2 1 GRAM domain YjeJ PF15922.5 GAM16971.1 - 0.021 14.1 0.1 0.04 13.1 0.1 1.4 1 0 0 1 1 1 0 YjeJ-like Glycos_transf_2 PF00535.26 GAM16972.1 - 1e-27 97.0 0.0 1.3e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAM16972.1 - 9.8e-09 35.4 0.0 1.4e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GAM16972.1 - 9.9e-06 25.2 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 GAM16972.1 - 0.00062 20.2 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 MFS_1 PF07690.16 GAM16972.1 - 0.12 11.2 0.6 0.16 10.9 0.6 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Ribosomal_L5e PF17144.4 GAM16974.1 - 4.4e-81 270.7 0.5 6.7e-81 270.1 0.5 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 GAM16974.1 - 1.2e-27 96.7 3.9 1.2e-27 96.7 3.9 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 GAM16974.1 - 0.047 13.9 0.1 0.65 10.3 0.0 2.5 1 1 1 2 2 2 0 Threonine synthase N terminus AIG1 PF04548.16 GAM16974.1 - 0.086 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family HSP90 PF00183.18 GAM16976.1 - 1.3e-227 756.8 37.1 1.7e-227 756.5 37.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GAM16976.1 - 2.2e-13 50.7 0.2 5.1e-13 49.5 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAM16976.1 - 5e-08 32.9 0.1 1.8e-07 31.0 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 GAM16976.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Peptidase_S24 PF00717.23 GAM16976.1 - 0.61 10.1 3.4 12 6.0 0.1 3.7 3 0 0 3 3 3 0 Peptidase S24-like Orthopox_A5L PF06193.11 GAM16978.1 - 1.5 8.2 5.6 0.54 9.6 2.8 1.6 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like Dickkopf_N PF04706.12 GAM16979.1 - 0.0075 16.7 5.9 0.0075 16.7 5.9 5.1 4 2 0 4 4 4 3 Dickkopf N-terminal cysteine-rich region SKG6 PF08693.10 GAM16980.1 - 0.0015 17.8 3.7 0.0031 16.9 3.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 GAM16980.1 - 0.033 15.0 0.1 0.076 13.9 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EGF_2 PF07974.13 GAM16980.1 - 0.32 11.4 12.8 0.59 10.6 12.8 1.5 1 0 0 1 1 1 0 EGF-like domain Ank_2 PF12796.7 GAM16981.1 - 9.5e-05 22.9 0.1 0.00094 19.7 0.0 2.7 1 1 2 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM16981.1 - 0.0062 17.0 0.1 4.9 8.0 0.0 3.6 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 GAM16981.1 - 0.018 15.6 1.0 1.3 9.7 0.0 3.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM16981.1 - 0.033 14.5 0.1 11 6.5 0.0 2.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 GAM16981.1 - 0.051 14.0 0.6 3.1 8.4 0.1 3.4 3 0 0 3 3 3 0 Ankyrin repeat Vault PF01505.18 GAM16983.1 - 4.7e-61 202.7 0.6 1.6e-15 57.0 0.0 5.2 5 0 0 5 5 5 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 GAM16983.1 - 1.3e-52 176.8 0.5 2.5e-52 175.9 0.5 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 GAM16983.1 - 1.1e-37 128.2 0.0 4.2e-23 81.5 0.0 2.6 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 GAM16983.1 - 1e-34 118.3 0.2 4.3e-30 103.5 0.0 3.5 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 GAM16983.1 - 1.3e-22 79.6 0.0 7.6e-22 77.2 0.0 2.4 1 0 0 1 1 1 1 Major Vault Protein repeat domain Frizzled PF01534.17 GAM16984.1 - 9.4e-09 34.7 19.8 1.7e-08 33.9 19.8 1.4 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 GAM16984.1 - 3.7e-08 33.0 16.3 3.7e-08 33.0 16.3 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) MscS_TM PF12794.7 GAM16984.1 - 0.033 13.1 2.7 0.064 12.1 2.7 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 TMF_TATA_bd PF12325.8 GAM16985.1 - 2.2e-29 102.0 13.6 2.2e-29 102.0 13.6 8.0 2 1 4 7 7 7 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 GAM16985.1 - 1.9e-18 66.2 11.9 1.9e-18 66.2 11.9 10.1 4 3 8 13 13 13 2 TATA element modulatory factor 1 DNA binding FAT PF02259.23 GAM16986.1 - 3.5e-109 365.2 2.0 3.5e-109 365.2 2.0 2.6 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 GAM16986.1 - 6e-73 245.7 0.2 1.7e-72 244.3 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 GAM16986.1 - 7.3e-69 230.8 1.7 9.2e-62 207.7 0.0 5.1 4 1 1 5 5 5 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 GAM16986.1 - 3.4e-41 139.7 0.2 3.4e-41 139.7 0.2 4.4 4 1 1 5 5 5 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 GAM16986.1 - 6.3e-17 61.7 13.1 0.0079 16.6 0.0 8.9 6 1 1 8 8 8 4 HEAT repeats Cnd1 PF12717.7 GAM16986.1 - 7.5e-16 58.6 0.5 0.00023 21.2 0.0 5.9 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 FATC PF02260.20 GAM16986.1 - 5.7e-14 51.6 0.6 1.4e-13 50.4 0.6 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 GAM16986.1 - 2.7e-13 48.9 24.3 0.029 14.6 0.0 11.9 15 0 0 15 15 11 4 HEAT repeat HEAT_EZ PF13513.6 GAM16986.1 - 2.6e-11 43.8 19.4 0.00059 20.3 0.1 11.6 11 1 1 12 12 11 3 HEAT-like repeat Sec7_N PF12783.7 GAM16986.1 - 9.7e-08 32.1 2.6 0.0068 16.3 0.4 4.9 4 1 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal UME PF08064.13 GAM16986.1 - 1.6e-05 24.7 8.6 0.04 13.8 0.1 7.2 6 2 2 8 8 8 1 UME (NUC010) domain IFRD PF05004.13 GAM16986.1 - 2.7e-05 23.4 0.3 0.0097 15.0 0.1 4.1 3 2 1 5 5 5 1 Interferon-related developmental regulator (IFRD) ParcG PF10274.9 GAM16986.1 - 4e-05 23.8 9.2 0.041 14.0 0.1 5.3 4 3 2 6 6 5 2 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 GAM16986.1 - 8.6e-05 23.1 1.5 29 5.3 0.0 6.1 7 1 0 7 7 4 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 GAM16986.1 - 0.00091 18.9 1.3 0.034 13.7 0.0 4.2 5 0 0 5 5 5 1 CLASP N terminal TPR_19 PF14559.6 GAM16986.1 - 0.095 13.2 0.3 1.6 9.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM16986.1 - 0.14 12.2 1.4 1.5 9.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 GAM16987.1 - 0.016 15.2 0.3 0.016 15.2 0.3 1.7 2 0 0 2 2 2 0 Prefoldin subunit LytR_cpsA_psr PF03816.14 GAM16988.1 - 0.054 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain Sulfotransfer_1 PF00685.27 GAM16989.1 - 0.22 11.0 0.1 0.24 10.8 0.1 1.1 1 0 0 1 1 1 0 Sulfotransferase domain Keratin_B2_2 PF13885.6 GAM16992.1 - 7.9 6.5 14.0 87 3.2 14.0 2.2 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein LCM PF04072.14 GAM16993.1 - 2.3e-39 135.3 0.0 5.3e-39 134.1 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Peptidase_C39_2 PF13529.6 GAM16996.1 - 3.2e-18 66.7 0.3 4.9e-18 66.1 0.3 1.3 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 GAM16996.1 - 1.8e-12 47.4 0.0 3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 GAM16996.1 - 3e-08 33.5 0.0 4.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase C39 family Guanylate_cyc_2 PF09778.9 GAM16996.1 - 8.7e-06 25.2 0.0 0.038 13.3 0.0 2.2 2 0 0 2 2 2 2 Guanylylate cyclase DUF3335 PF11814.8 GAM16996.1 - 0.0022 17.5 0.0 0.0047 16.4 0.0 1.5 2 0 0 2 2 2 1 Peptidase_C39 like family RQC PF09382.10 GAM16996.1 - 0.099 12.4 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 RQC domain FNIP PF05725.12 GAM16997.1 - 1.7e-11 44.1 8.2 0.001 19.2 0.3 5.0 3 1 1 4 4 4 4 FNIP Repeat FNIP PF05725.12 GAM16998.1 - 6.3e-13 48.7 26.2 0.00012 22.2 0.7 6.5 4 2 4 8 8 8 6 FNIP Repeat NTP_transf_7 PF07984.12 GAM16999.1 - 1.2e-30 106.8 5.1 3.2e-24 85.7 2.3 2.1 2 0 0 2 2 2 2 Nucleotidyltransferase DUF4770 PF15994.5 GAM16999.1 - 0.84 9.9 5.9 0.25 11.6 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) WBS_methylT PF12589.8 GAM17000.1 - 2.2e-17 63.6 7.1 3.7e-17 62.8 7.1 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 GAM17000.1 - 8.7e-12 45.5 0.0 1.4e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM17000.1 - 6.3e-11 42.8 0.0 1.4e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM17000.1 - 5.9e-05 23.7 0.0 0.00017 22.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM17000.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM17000.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 GAM17000.1 - 0.0044 16.8 0.0 0.12 12.0 0.0 2.2 2 1 0 2 2 2 1 DNA methylase CMAS PF02353.20 GAM17000.1 - 0.014 14.7 0.0 0.028 13.7 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 GAM17000.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.13 GAM17000.1 - 0.17 12.2 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Ras PF00071.22 GAM17001.1 - 5.4e-40 136.6 0.0 3.3e-24 85.3 0.0 2.3 2 0 0 2 2 2 2 Ras family PH PF00169.29 GAM17001.1 - 2.6e-14 53.6 0.3 6.1e-14 52.4 0.3 1.7 1 0 0 1 1 1 1 PH domain Roc PF08477.13 GAM17001.1 - 4.4e-13 49.5 0.6 1.8e-07 31.4 0.0 3.0 4 0 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase PH_6 PF15406.6 GAM17001.1 - 1.6e-05 25.1 0.1 4.6e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_4 PF15404.6 GAM17001.1 - 7.2e-05 22.7 0.2 0.00016 21.5 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAM17001.1 - 0.011 16.1 0.4 0.034 14.6 0.4 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PH_5 PF15405.6 GAM17001.1 - 0.067 13.3 0.1 0.23 11.6 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Coatomer_E PF04733.14 GAM17002.1 - 5.5e-95 318.1 6.3 6.1e-95 318.0 6.3 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 GAM17002.1 - 1.6e-06 28.5 10.6 0.00058 20.3 0.1 4.9 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM17002.1 - 7.9e-06 25.5 2.3 0.5 10.3 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM17002.1 - 3.4e-05 24.3 4.7 2 9.5 0.0 5.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM17002.1 - 5e-05 23.9 1.5 0.36 11.5 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM17002.1 - 9.6e-05 22.6 3.5 0.08 13.2 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat PPR_2 PF13041.6 GAM17002.1 - 0.00065 19.8 0.1 1.8 8.8 0.0 3.8 4 0 0 4 4 3 1 PPR repeat family ANAPC3 PF12895.7 GAM17002.1 - 0.00086 19.5 8.5 0.0035 17.5 0.3 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 GAM17002.1 - 0.0012 17.9 3.2 0.027 13.4 0.3 2.2 1 1 2 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 GAM17002.1 - 0.0012 18.8 11.7 0.21 11.8 0.0 4.8 6 0 0 6 6 5 2 Tetratricopeptide repeat PPR PF01535.20 GAM17002.1 - 0.0053 16.9 5.2 8.4 6.9 0.0 4.4 5 0 0 5 5 5 1 PPR repeat SRP_TPR_like PF17004.5 GAM17002.1 - 0.0057 16.7 4.4 0.059 13.4 0.2 3.0 1 1 3 4 4 4 1 Putative TPR-like repeat TPR_6 PF13174.6 GAM17002.1 - 0.013 16.1 0.6 33 5.4 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 GAM17002.1 - 0.024 14.3 0.2 5.9 6.5 0.0 3.4 2 2 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 GAM17002.1 - 0.054 13.9 8.7 1.1 9.8 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Utp13 PF08625.11 GAM17002.1 - 0.066 13.1 1.0 0.099 12.5 0.2 1.7 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain TPR_4 PF07721.14 GAM17002.1 - 0.11 13.2 0.1 8.3 7.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM17002.1 - 0.54 10.0 0.1 0.54 10.0 0.1 3.5 4 0 0 4 4 4 0 TPR repeat TPR_8 PF13181.6 GAM17002.1 - 3.6 8.1 9.4 1.4 9.3 0.1 4.3 6 0 0 6 6 5 0 Tetratricopeptide repeat CD36 PF01130.21 GAM17003.1 - 5.4e-54 183.5 18.7 1.6e-32 112.6 4.2 2.4 2 1 0 2 2 2 2 CD36 family PorA PF11271.8 GAM17003.1 - 0.052 12.8 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Porin PorA S_2TMBeta PF18153.1 GAM17004.1 - 0.047 13.5 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain FAM176 PF14851.6 GAM17005.1 - 0.0016 18.1 2.3 0.0038 16.9 2.3 1.6 1 0 0 1 1 1 1 FAM176 family TLP-20 PF06088.11 GAM17005.1 - 0.012 15.5 1.5 0.035 14.0 1.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Cwf_Cwc_15 PF04889.12 GAM17005.1 - 0.016 14.9 9.2 0.032 14.0 9.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 GAM17005.1 - 0.024 12.7 6.0 0.038 12.1 6.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ACDC PF14733.6 GAM17005.1 - 0.04 14.2 1.7 3.7 7.9 0.1 3.7 3 0 0 3 3 3 0 AP2-coincident C-terminal UME PF08064.13 GAM17005.1 - 0.052 13.5 0.2 3.8 7.5 0.0 3.2 3 0 0 3 3 3 0 UME (NUC010) domain BUD22 PF09073.10 GAM17005.1 - 0.12 11.7 6.9 0.067 12.5 5.0 1.5 2 0 0 2 2 2 0 BUD22 Tom22 PF04281.13 GAM17005.1 - 0.14 11.9 3.3 0.38 10.5 3.3 1.8 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 RXT2_N PF08595.11 GAM17005.1 - 0.2 11.7 11.1 0.55 10.2 11.1 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal GCIP PF13324.6 GAM17005.1 - 0.6 9.7 11.3 0.16 11.6 3.4 3.7 4 0 0 4 4 4 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 GAM17005.1 - 2.1 6.4 19.6 2.2 6.3 17.2 2.1 2 0 0 2 2 2 0 DNA polymerase phi CDC45 PF02724.14 GAM17005.1 - 9.6 4.4 13.0 20 3.3 13.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 GAM17005.1 - 9.7 6.5 10.0 19 5.5 10.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FNIP PF05725.12 GAM17006.1 - 2.9e-62 206.6 14.0 2.4e-11 43.6 0.4 7.5 5 1 1 7 7 7 6 FNIP Repeat LRR_5 PF13306.6 GAM17006.1 - 3.7e-05 23.7 0.0 0.043 13.8 0.0 3.8 1 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 GAM17006.1 - 5.5 7.9 7.3 20 6.2 0.1 5.2 5 2 0 5 5 5 0 Leucine Rich Repeat tRNA-synt_1g PF09334.11 GAM17007.1 - 2.8e-105 352.3 0.0 1.3e-104 350.0 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAM17007.1 - 3.6e-19 68.5 5.8 8.2e-11 40.9 0.2 4.1 4 1 0 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 GAM17007.1 - 1.3e-08 34.6 0.0 0.0019 17.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 GAM17007.1 - 3.1e-07 30.5 0.0 6.6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Uma2 PF05685.12 GAM17008.1 - 0.0037 16.8 0.0 0.01 15.4 0.0 1.6 1 1 1 2 2 2 1 Putative restriction endonuclease Nfu_N PF08712.11 GAM17009.1 - 3.4e-30 103.9 0.3 4.5e-29 100.4 0.0 2.3 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 GAM17009.1 - 1e-24 86.4 0.1 1.7e-24 85.7 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain DUF2048 PF09752.9 GAM17010.1 - 0.041 13.0 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Ank_2 PF12796.7 GAM17012.1 - 2.4e-11 44.0 0.2 0.19 12.4 0.0 7.2 8 0 0 8 8 8 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM17012.1 - 6.6e-05 23.4 2.3 2.1 9.0 0.0 6.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) PRKCSH-like PF12999.7 GAM17013.1 - 3.6e-41 140.9 7.4 3.6e-41 140.9 7.4 2.5 1 1 1 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 GAM17013.1 - 8.2e-30 103.5 0.6 8.2e-30 103.5 0.6 2.5 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein Exonuc_VII_L PF02601.15 GAM17013.1 - 0.013 15.1 10.9 0.019 14.6 10.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PRKCSH PF07915.13 GAM17013.1 - 0.02 15.9 2.3 0.02 15.9 2.3 3.1 2 1 0 2 2 2 0 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 GAM17013.1 - 0.12 12.6 12.8 0.096 12.9 1.8 2.8 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A DDHD PF02862.17 GAM17013.1 - 0.23 11.6 4.0 0.31 11.2 4.0 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 GAM17013.1 - 0.77 8.5 7.5 0.98 8.1 7.5 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 GAM17013.1 - 1.6 7.5 11.5 2.1 7.1 11.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter NPV_P10 PF05531.12 GAM17013.1 - 3.7 8.1 11.2 1.2 9.6 1.7 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Neur_chan_memb PF02932.16 GAM17013.1 - 6 6.9 6.6 8.7 6.3 6.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sugar_tr PF00083.24 GAM17014.1 - 7.8e-99 331.6 33.9 8.9e-99 331.4 33.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM17014.1 - 1.4e-28 99.9 40.6 6.7e-27 94.3 28.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 GAM17015.1 - 8.7e-25 86.5 17.7 3.5e-08 34.0 0.6 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17015.1 - 9.5e-18 64.3 8.3 2.4e-07 31.0 0.5 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM17015.1 - 1.2e-06 28.6 2.8 0.016 15.1 0.1 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM17015.1 - 1.7e-06 27.2 3.8 0.0061 15.6 1.4 4.4 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 GAM17015.1 - 0.0016 16.6 0.7 0.52 8.2 0.0 2.4 2 0 0 2 2 2 2 IKI3 family DPPIV_N PF00930.21 GAM17015.1 - 0.0076 15.1 0.4 0.15 10.8 0.1 2.3 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region GST_C_3 PF14497.6 GAM17016.1 - 1.5e-12 47.6 1.3 2.5e-12 46.9 1.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM17016.1 - 4.3e-12 46.1 0.1 7.3e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM17016.1 - 7.9e-12 45.4 1.0 2.9e-10 40.3 0.0 2.8 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM17016.1 - 7.2e-11 42.0 0.0 1.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM17016.1 - 3.9e-10 39.9 0.0 9.2e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAM17016.1 - 4.4e-10 39.8 0.0 8.2e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Mito_carr PF00153.27 GAM17017.1 - 4.3e-75 247.7 3.9 6.6e-25 86.9 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 GAM17017.1 - 4.2e-12 44.7 4.8 7.3e-07 28.3 0.9 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAM17017.1 - 1.7e-11 44.4 3.9 3.1e-11 43.6 3.9 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM17017.1 - 1.2e-09 37.3 4.3 1.4e-06 27.7 1.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAM17017.1 - 1.2e-07 30.9 3.6 3.1e-06 26.4 1.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 GAM17017.1 - 3.7e-06 26.7 6.4 4.5e-06 26.4 1.9 2.4 1 1 1 2 2 2 2 EF-hand domain pair DUF5580 PF17743.1 GAM17017.1 - 0.0019 16.8 0.0 0.0026 16.4 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SPARC_Ca_bdg PF10591.9 GAM17017.1 - 0.0045 17.3 0.8 0.007 16.7 0.8 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 GAM17017.1 - 0.11 12.4 0.3 0.59 10.0 0.1 2.2 1 1 1 2 2 2 0 Caleosin related protein Serine_protease PF18405.1 GAM17017.1 - 0.12 11.5 1.5 3.1 6.9 0.0 3.4 4 1 0 4 4 4 0 Gammaproteobacterial serine protease Ribosomal_S28e PF01200.18 GAM17018.1 - 2.2e-31 107.6 1.2 2.5e-31 107.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ceramidase_alk PF04734.13 GAM17019.1 - 2.3e-213 709.5 0.0 2.7e-213 709.2 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 GAM17019.1 - 2.5e-47 160.9 1.3 4.8e-47 159.9 1.3 1.5 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal FNIP PF05725.12 GAM17020.1 - 2.6e-108 354.0 24.6 2.2e-13 50.1 0.0 10.7 5 3 1 10 10 10 10 FNIP Repeat DUF1769 PF08588.10 GAM17020.1 - 0.00052 20.2 12.2 3.7 7.8 0.0 8.5 11 1 0 11 11 11 1 Protein of unknown function (DUF1769) Glyco_hydro_65C PF03633.15 GAM17020.1 - 0.27 11.2 0.6 1.5e+02 2.4 0.1 5.0 8 0 0 8 8 8 0 Glycosyl hydrolase family 65, C-terminal domain NPL4 PF05021.15 GAM17021.1 - 4.2e-26 92.0 1.4 1.6e-14 54.0 0.1 3.4 1 1 1 2 2 2 2 NPL4 family JAB PF01398.21 GAM17021.1 - 2.1e-06 27.7 0.0 3.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ANAPC4_WD40 PF12894.7 GAM17023.1 - 3.4e-09 36.9 0.0 0.086 13.1 0.0 5.0 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM17023.1 - 7.4e-07 29.8 15.3 0.62 11.0 0.1 6.2 5 1 1 6 6 6 3 WD domain, G-beta repeat PD40 PF07676.12 GAM17023.1 - 0.048 13.6 0.0 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ank_2 PF12796.7 GAM17024.1 - 9.1e-41 138.3 20.4 3.5e-08 33.9 0.0 7.0 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM17024.1 - 3.8e-33 113.4 16.6 2.3e-05 24.8 0.0 10.2 5 3 7 13 13 13 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM17024.1 - 5.1e-28 96.8 25.3 0.0085 16.4 0.0 14.7 3 2 13 16 16 16 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM17024.1 - 4.7e-18 63.4 18.6 0.82 10.4 0.0 16.0 13 3 5 18 18 18 2 Ankyrin repeat DUF3447 PF11929.8 GAM17024.1 - 6.6e-07 29.2 4.0 1.1 9.3 0.1 5.7 4 2 2 6 6 6 3 Domain of unknown function (DUF3447) Ank PF00023.30 GAM17024.1 - 6.6e-05 23.2 21.2 12 6.6 0.1 12.2 4 2 4 8 8 8 1 Ankyrin repeat PH PF00169.29 GAM17025.1 - 4.4e-17 62.5 0.4 1.3e-16 61.0 0.4 1.7 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 GAM17025.1 - 2.4e-11 43.0 0.9 7.1e-11 41.6 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 GAM17025.1 - 3.4e-09 36.4 1.2 3.8e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 GAM17025.1 - 2.7e-07 30.2 0.0 6.3e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 GAM17025.1 - 0.0014 19.0 1.6 0.0014 19.0 1.6 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain Pepsin-I3 PF06394.13 GAM17025.1 - 0.068 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain BUD22 PF09073.10 GAM17025.1 - 0.078 12.3 6.3 0.1 11.9 6.3 1.1 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 GAM17025.1 - 0.087 11.4 6.7 0.13 10.9 6.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PH_8 PF15409.6 GAM17025.1 - 0.14 12.5 0.4 0.65 10.3 0.4 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Importin_rep_4 PF18808.1 GAM17025.1 - 0.14 12.5 1.6 0.3 11.4 1.6 1.5 1 0 0 1 1 1 0 Importin repeat FAM104 PF15434.6 GAM17025.1 - 0.21 12.1 10.5 0.46 11.1 10.5 1.5 1 0 0 1 1 1 0 Family 104 Pex14_N PF04695.13 GAM17025.1 - 0.32 11.6 7.3 0.57 10.8 7.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 7tm_3 PF00003.22 GAM17026.1 - 3.7e-26 92.3 16.6 5.7e-26 91.7 16.6 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DASH_Spc19 PF08287.11 GAM17027.1 - 0.0011 18.9 15.8 0.0013 18.7 10.0 2.8 1 1 1 2 2 2 2 Spc19 Herpes_UL6 PF01763.16 GAM17027.1 - 0.032 12.7 4.1 0.04 12.4 4.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like CCDC-167 PF15188.6 GAM17027.1 - 1.8 9.0 9.4 0.45 10.9 5.4 2.1 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 NPV_P10 PF05531.12 GAM17027.1 - 1.9 9.0 13.8 13 6.4 1.0 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.6 GAM17027.1 - 3 8.3 9.0 3.9 8.0 2.4 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Fzo_mitofusin PF04799.13 GAM17027.1 - 3.6 7.1 7.8 2.9 7.4 4.2 2.1 1 1 1 2 2 2 0 fzo-like conserved region MFS_1 PF07690.16 GAM17028.1 - 5.8e-35 120.8 43.3 2.8e-27 95.6 32.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM17028.1 - 4.8e-09 35.6 31.5 9.2e-09 34.7 31.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter BT1 PF03092.16 GAM17028.1 - 0.97 7.6 18.4 0.23 9.7 2.5 2.7 3 0 0 3 3 3 0 BT1 family BAR_3 PF16746.5 GAM17029.1 - 1.8e-69 234.1 17.7 2.6e-69 233.6 17.7 1.2 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 GAM17029.1 - 9.6e-36 122.4 0.0 4e-35 120.4 0.0 2.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_5 PF13857.6 GAM17029.1 - 1.4e-14 53.9 2.3 1.8e-11 44.0 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 GAM17029.1 - 1.4e-12 48.0 0.1 3.9e-12 46.6 0.1 1.8 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 GAM17029.1 - 1.7e-12 47.7 2.7 1.6e-08 35.0 0.6 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM17029.1 - 3.7e-11 43.3 0.6 5.1e-09 36.5 0.1 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM17029.1 - 1.6e-09 37.2 1.2 0.057 14.0 0.2 4.4 4 0 0 4 4 4 3 Ankyrin repeat BAR PF03114.18 GAM17029.1 - 2.9e-06 27.1 9.0 2.9e-06 27.1 9.0 1.8 2 0 0 2 2 2 1 BAR domain Ank PF00023.30 GAM17029.1 - 0.00044 20.6 1.9 0.12 12.9 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeat PH_11 PF15413.6 GAM17029.1 - 0.0027 18.1 1.3 0.047 14.1 1.3 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain FAM92 PF06730.11 GAM17029.1 - 0.02 14.3 3.0 0.041 13.3 3.0 1.5 1 0 0 1 1 1 0 FAM92 protein Phasin_2 PF09361.10 GAM17029.1 - 0.077 13.3 2.6 0.21 11.9 0.1 2.8 3 0 0 3 3 3 0 Phasin protein SOAR PF16533.5 GAM17029.1 - 9.2 6.3 7.5 1.8 8.6 2.7 2.2 2 0 0 2 2 2 0 STIM1 Orai1-activating region RRM_1 PF00076.22 GAM17030.1 - 6.5e-18 64.3 0.5 1.4e-07 31.2 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.22 GAM17030.1 - 3.6e-11 42.9 0.0 9e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 R3H domain SUZ-C PF12901.7 GAM17030.1 - 4.1e-05 23.5 2.2 0.00014 21.8 0.2 2.8 2 0 0 2 2 2 1 SUZ-C motif Limkain-b1 PF11608.8 GAM17030.1 - 0.00055 20.0 0.2 0.38 10.9 0.1 2.9 2 1 0 2 2 2 2 Limkain b1 DbpA PF03880.15 GAM17030.1 - 0.0076 16.2 0.0 2.6 8.1 0.0 2.4 2 0 0 2 2 2 2 DbpA RNA binding domain Nup35_RRM_2 PF14605.6 GAM17030.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 GAM17030.1 - 0.035 13.7 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAM17030.1 - 0.18 11.8 0.2 2.7 8.1 0.1 2.2 2 0 0 2 2 2 0 RNA binding motif Mannitol_dh_C PF08125.13 GAM17031.1 - 1.1e-70 237.9 0.0 1.5e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 GAM17031.1 - 1.3e-28 100.1 0.1 3.3e-28 98.7 0.1 1.7 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain FANCL_C PF11793.8 GAM17031.1 - 0.027 14.6 0.1 0.069 13.3 0.1 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain UQ_con PF00179.26 GAM17032.1 - 8.6e-46 155.1 0.0 9.5e-46 154.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM17032.1 - 0.0033 17.1 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAM17032.1 - 0.0042 17.4 0.1 0.0054 17.0 0.1 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 GAM17032.1 - 0.084 12.7 0.1 0.099 12.5 0.1 1.2 1 0 0 1 1 1 0 UEV domain 2OG-FeII_Oxy_2 PF13532.6 GAM17033.1 - 1.1e-42 146.5 0.6 9.6e-42 143.4 0.0 2.4 2 1 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAM17033.1 - 0.085 13.3 0.0 16 6.1 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily TrmO PF01980.16 GAM17034.1 - 1.2e-36 125.5 0.2 1.3e-35 122.2 0.2 2.1 1 1 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 GAM17034.1 - 0.00029 20.9 0.0 0.00092 19.3 0.0 1.8 2 0 0 2 2 2 1 TrmO C-terminal domain IglC PF11550.8 GAM17034.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Intracellular growth locus C protein MBOAT PF03062.19 GAM17035.1 - 1.6e-28 100.0 31.1 1.6e-28 100.0 31.1 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Vinculin PF01044.19 GAM17036.1 - 5.8e-38 130.8 48.8 5e-15 54.9 19.4 4.9 2 2 2 4 4 4 4 Vinculin family LcrG PF07216.12 GAM17036.1 - 0.016 15.1 0.0 0.016 15.1 0.0 3.3 2 1 0 2 2 2 0 LcrG protein NTP_transf_4 PF13562.6 GAM17036.1 - 0.074 13.3 1.1 8.4 6.6 0.1 2.9 2 0 0 2 2 2 0 Sugar nucleotidyl transferase SICA_C PF12879.7 GAM17036.1 - 0.094 12.7 3.1 0.88 9.6 0.9 2.8 1 1 1 2 2 2 0 SICA C-terminal inner membrane domain MIOX PF05153.15 GAM17036.1 - 0.095 12.3 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Myo-inositol oxygenase SpoIIID PF12116.8 GAM17036.1 - 0.19 11.9 2.2 5.5 7.2 0.1 3.6 2 1 1 3 3 3 0 Stage III sporulation protein D Apolipoprotein PF01442.18 GAM17036.1 - 0.24 11.2 22.8 0.013 15.4 7.6 4.5 3 1 2 5 5 5 0 Apolipoprotein A1/A4/E domain DUF2205 PF10224.9 GAM17036.1 - 0.37 10.8 0.0 0.37 10.8 0.0 3.8 4 0 0 4 4 4 0 Short coiled-coil protein Iron_permease PF04120.12 GAM17036.1 - 1.6 8.5 4.4 7.7 6.3 0.3 3.3 3 0 0 3 3 3 0 Low affinity iron permease I_LWEQ PF01608.17 GAM17036.1 - 2.4 8.4 45.3 0.6 10.3 1.9 7.1 5 2 2 7 7 7 0 I/LWEQ domain P53_C PF11619.8 GAM17036.1 - 3.2 7.9 13.7 1.2 9.3 0.4 4.5 4 1 1 5 5 4 0 Transcription factor P53 - C terminal domain PMC2NT PF08066.12 GAM17036.1 - 3.9 8.2 13.1 6.4 7.5 0.1 5.3 3 2 2 5 5 5 0 PMC2NT (NUC016) domain AAA_33 PF13671.6 GAM17036.1 - 4.2 7.5 7.7 0.53 10.4 1.4 2.6 3 0 0 3 3 3 0 AAA domain Hrs_helical PF12210.8 GAM17036.1 - 4.9 7.8 10.7 10 6.8 0.7 3.6 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate G-alpha PF00503.20 GAM17036.1 - 4.9 6.2 8.3 17 4.5 2.5 3.0 2 1 0 2 2 2 0 G-protein alpha subunit CbiA PF01656.23 GAM17036.1 - 4.9 7.2 7.4 26 4.9 0.1 3.9 2 1 1 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2357 PF09823.9 GAM17036.1 - 6.2 6.0 6.6 6.5 5.9 0.6 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2357) LETM1 PF07766.13 GAM17037.1 - 3.2e-22 79.2 2.1 2e-10 40.4 0.1 2.1 1 1 1 2 2 2 2 LETM1-like protein E1-E2_ATPase PF00122.20 GAM17038.1 - 6.1e-51 172.5 1.7 6.1e-51 172.5 1.7 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM17038.1 - 3.8e-48 164.6 0.3 6e-48 163.9 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAM17038.1 - 5.7e-23 81.1 0.6 3.6e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GAM17038.1 - 1.8e-05 24.6 0.6 0.0011 18.8 0.7 2.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3671 PF12420.8 GAM17038.1 - 0.15 12.2 1.2 2.4 8.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function Sigma_reg_N PF13800.6 GAM17038.1 - 1.2 9.5 3.2 12 6.3 0.0 3.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Peptidase_M24 PF00557.24 GAM17039.1 - 2.7e-38 131.8 0.1 4.4e-38 131.1 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 FRQ PF09421.10 GAM17039.1 - 0.013 13.5 3.7 0.019 13.0 3.7 1.1 1 0 0 1 1 1 0 Frequency clock protein Rrn6 PF10214.9 GAM17039.1 - 0.04 12.4 1.0 0.054 12.0 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MLD PF11647.8 GAM17039.1 - 0.13 12.5 0.3 21 5.5 0.0 2.4 2 0 0 2 2 2 0 Membrane Localization Domain CDC45 PF02724.14 GAM17039.1 - 0.48 8.7 2.3 0.63 8.3 2.3 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 GAM17039.1 - 0.6 10.2 12.9 1.1 9.3 12.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NST1 PF13945.6 GAM17039.1 - 1.2 9.2 9.3 1.7 8.7 8.6 1.5 1 1 0 1 1 1 0 Salt tolerance down-regulator zf-DBF PF07535.12 GAM17040.1 - 8.3e-19 67.4 2.4 2.4e-18 66.0 2.4 1.8 1 0 0 1 1 1 1 DBF zinc finger SUIM_assoc PF16619.5 GAM17040.1 - 0.00019 21.4 0.2 0.00019 21.4 0.2 3.3 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 zf-C2H2_2 PF12756.7 GAM17040.1 - 0.0036 17.6 8.8 0.015 15.6 8.8 2.1 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Peptidase_M48 PF01435.18 GAM17041.1 - 4.5e-26 91.8 0.1 1e-25 90.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M48_N PF16491.5 GAM17041.1 - 2.7e-20 73.0 9.7 2.7e-20 73.0 9.7 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M56 PF05569.11 GAM17041.1 - 6.6e-06 25.5 1.1 1.1e-05 24.7 0.7 1.5 2 0 0 2 2 2 1 BlaR1 peptidase M56 Babuvirus_MP PF07234.11 GAM17041.1 - 0.02 15.1 5.5 0.032 14.4 0.8 2.7 2 0 0 2 2 2 0 Movement and RNA silencing protein DCX PF03607.17 GAM17041.1 - 0.029 14.5 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Doublecortin Steroid_dh PF02544.16 GAM17042.1 - 3.6e-39 134.1 1.0 3.6e-39 134.1 1.0 2.3 3 0 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 GAM17042.1 - 4.3e-05 23.2 1.8 0.00026 20.7 1.8 2.0 1 1 0 1 1 1 1 Ubiquitin family PEMT PF04191.13 GAM17042.1 - 7.1e-05 23.2 0.4 0.00019 21.8 0.4 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 GAM17042.1 - 8.5e-05 22.2 0.8 0.00013 21.6 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ubiquitin_4 PF18036.1 GAM17042.1 - 0.01 15.8 0.7 0.39 10.8 0.7 2.4 1 1 0 1 1 1 0 Ubiquitin-like domain FNIP PF05725.12 GAM17043.1 - 3.1e-103 337.7 37.1 4e-15 55.7 0.6 10.3 10 0 0 10 10 10 10 FNIP Repeat Coiled PF05710.12 GAM17044.1 - 3.1e-06 27.9 26.3 5.4e-06 27.1 26.3 1.5 1 1 0 1 1 1 1 Coiled coil GRP PF07172.11 GAM17044.1 - 6.7 7.5 12.8 8.5 7.2 12.8 1.2 1 0 0 1 1 1 0 Glycine rich protein family CE2_N PF17996.1 GAM17045.1 - 5.3e-14 52.1 0.0 1.2e-13 51.0 0.0 1.6 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 GAM17045.1 - 5.4e-13 49.7 0.0 1e-12 48.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM17045.1 - 1.4e-09 38.2 0.0 4.7e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MIP PF00230.20 GAM17046.1 - 1.9e-33 116.1 13.7 2.6e-33 115.6 13.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein MSP1a PF11670.8 GAM17046.1 - 0.78 9.0 2.7 1.6 7.9 2.7 1.6 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) FNIP PF05725.12 GAM17047.1 - 5.6e-48 160.9 0.2 1.4e-11 44.3 0.6 6.3 3 1 2 6 6 6 6 FNIP Repeat Pkinase PF00069.25 GAM17047.1 - 4.5e-34 118.0 2.8 1.1e-23 84.0 2.5 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17047.1 - 3.7e-17 62.5 0.0 2.8e-14 53.0 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GAM17047.1 - 0.0012 18.9 0.1 0.15 12.0 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family HTH_ABP1_N PF18107.1 GAM17047.1 - 0.04 13.6 0.0 11 5.8 0.0 3.3 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Nop14 PF04147.12 GAM17047.1 - 0.35 9.0 3.4 0.6 8.3 3.4 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAM17047.1 - 7 6.0 9.1 0.48 9.8 4.0 1.6 2 0 0 2 2 2 0 SDA1 FNIP PF05725.12 GAM17048.1 - 1.2e-44 150.2 7.6 9.6e-14 51.3 0.3 4.3 4 0 0 4 4 4 4 FNIP Repeat Peptidase_C39_2 PF13529.6 GAM17049.1 - 1.2e-16 61.6 3.8 3.4e-08 34.2 0.7 2.3 1 1 1 2 2 2 2 Peptidase_C39 like family Peptidase_C70 PF12385.8 GAM17049.1 - 0.0046 16.9 0.7 2.1 8.3 0.1 2.7 2 1 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 Lipase_2 PF01674.18 GAM17049.1 - 0.023 14.2 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) Peptidase_C39 PF03412.15 GAM17049.1 - 0.052 13.4 1.0 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Peptidase C39 family GST_C PF00043.25 GAM17050.1 - 3.9e-11 43.0 0.0 7.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM17050.1 - 2.9e-10 40.3 0.0 7.3e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAM17050.1 - 2.4e-09 37.5 0.0 5.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM17050.1 - 6.8e-08 32.4 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM17050.1 - 1.4e-07 31.7 0.0 2.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM17050.1 - 3.4e-07 30.4 0.0 6.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Raptor_N PF14538.6 GAM17051.1 - 7.4e-72 240.1 0.1 2.1e-71 238.6 0.1 1.9 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 GAM17051.1 - 9.2e-11 42.1 11.9 1.9 9.5 0.0 7.6 8 0 0 8 8 8 4 WD domain, G-beta repeat HEAT PF02985.22 GAM17051.1 - 7.3e-09 35.1 6.9 0.15 12.4 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 GAM17051.1 - 1.3e-05 25.3 0.2 0.0019 18.2 0.0 3.2 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM17051.1 - 8.4e-05 22.9 1.2 0.012 16.0 0.0 3.3 4 0 0 4 4 4 1 HEAT repeats ANAPC4_WD40 PF12894.7 GAM17051.1 - 0.00031 21.0 0.0 12 6.3 0.0 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 GAM17051.1 - 0.069 13.2 0.1 0.069 13.2 0.1 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HEAT_EZ PF13513.6 GAM17051.1 - 0.092 13.3 0.0 0.092 13.3 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat Adaptin_N PF01602.20 GAM17051.1 - 0.11 11.0 0.3 1 7.8 0.0 2.4 2 1 1 3 3 3 0 Adaptin N terminal region DUF885 PF05960.11 GAM17052.1 - 1.4e-138 463.9 0.3 1.7e-138 463.6 0.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF3561 PF12084.8 GAM17052.1 - 1.5 8.9 3.9 2.6 8.1 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) Coiled PF05710.12 GAM17053.1 - 0.014 16.2 17.6 0.072 13.9 17.6 1.9 1 1 0 1 1 1 0 Coiled coil ABC_membrane PF00664.23 GAM17055.1 - 2.3e-63 214.4 29.0 1.3e-35 123.4 7.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM17055.1 - 1.8e-42 145.1 0.1 2.4e-22 79.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 GAM17055.1 - 5.8e-05 22.8 2.2 0.027 14.2 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 GAM17055.1 - 0.00013 21.5 3.4 0.05 13.0 0.1 3.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAM17055.1 - 0.00025 21.1 0.9 1.1 9.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM17055.1 - 0.00048 20.1 1.3 0.13 12.1 0.2 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 GAM17055.1 - 0.0017 18.0 0.1 0.13 11.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM17055.1 - 0.0024 18.2 0.1 1.3 9.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM17055.1 - 0.0054 17.1 1.3 0.69 10.3 0.5 2.7 2 0 0 2 2 2 1 AAA ATPase domain RNA_pol_Rpc4 PF05132.14 GAM17055.1 - 0.0094 16.4 4.9 0.12 12.8 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase III RPC4 AAA_21 PF13304.6 GAM17055.1 - 0.03 14.1 0.1 0.03 14.1 0.1 4.7 4 1 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 GAM17055.1 - 0.12 11.9 0.4 7.4 6.0 0.2 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 GAM17055.1 - 0.15 11.4 0.1 11 5.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 GAM17055.1 - 0.16 11.3 0.3 17 4.6 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 GAM17055.1 - 0.17 11.5 4.3 0.42 10.2 0.7 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 GAM17055.1 - 0.19 10.8 0.0 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NOA36 PF06524.12 GAM17055.1 - 0.24 10.7 18.8 0.023 14.0 2.3 2.2 2 0 0 2 2 2 0 NOA36 protein AP3D1 PF06375.11 GAM17055.1 - 0.65 10.2 18.8 0.87 9.8 5.0 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Pkr1 PF08636.10 GAM17055.1 - 0.7 10.1 7.8 0.045 13.9 1.0 2.7 2 0 0 2 2 1 0 ER protein Pkr1 CDC45 PF02724.14 GAM17055.1 - 0.97 7.6 19.7 0.11 10.7 4.9 2.2 2 0 0 2 2 2 0 CDC45-like protein AAA_23 PF13476.6 GAM17055.1 - 2.5 8.6 24.2 2.2 8.7 0.2 3.8 3 1 0 3 3 3 0 AAA domain RNA_pol_3_Rpc31 PF11705.8 GAM17055.1 - 4.3 7.5 21.3 0.73 10.0 11.5 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 EIIBC-GUT_N PF03612.14 GAM17055.1 - 4.6 6.9 6.3 9.5 5.9 0.3 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Cytomega_UL84 PF06284.11 GAM17055.1 - 5.8 5.2 8.5 12 4.2 8.5 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein PTPRCAP PF15713.5 GAM17055.1 - 8.3 6.7 15.7 5 7.4 0.3 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Acetyltransf_10 PF13673.7 GAM17056.1 - 2.3e-08 34.0 0.0 3.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM17056.1 - 1.7e-06 28.3 0.0 2.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM17056.1 - 0.00011 22.6 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 GAM17057.1 - 1.5e-73 247.4 0.0 2e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17057.1 - 1.3e-33 116.4 0.0 1.8e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 GAM17057.1 - 4e-18 65.5 0.3 2.1e-17 63.2 0.1 2.4 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 GAM17057.1 - 5.6e-11 42.3 0.0 8.1e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 GAM17057.1 - 7.2e-09 35.8 0.0 1.8e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Haspin_kinase PF12330.8 GAM17057.1 - 9.4e-06 24.8 0.0 0.00017 20.6 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAM17057.1 - 0.00014 21.3 1.1 0.00016 21.1 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM17057.1 - 0.026 14.4 0.2 0.076 12.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family FHA_2 PF17913.1 GAM17057.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 FHA domain RAMA PF18755.1 GAM17059.1 - 5.3e-13 49.3 0.0 1.5e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated bPH_4 PF06713.11 GAM17059.1 - 0.046 13.8 0.2 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial PH domain DUF2312 PF10073.9 GAM17059.1 - 0.075 12.7 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) MOSC PF03473.17 GAM17060.1 - 3.2e-06 27.2 0.0 5.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 MOSC domain FNIP PF05725.12 GAM17062.1 - 2.2e-18 66.1 11.6 0.0027 17.8 0.0 8.5 8 1 0 8 8 8 5 FNIP Repeat Gag_p30 PF02093.16 GAM17062.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Gag P30 core shell protein WND PF07861.11 GAM17062.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 WisP family N-Terminal Region LRR_4 PF12799.7 GAM17062.1 - 0.8 10.2 16.3 12 6.5 1.4 6.8 8 1 0 8 8 8 0 Leucine Rich repeats (2 copies) HD PF01966.22 GAM17063.1 - 7.6e-15 55.2 2.0 1.4e-14 54.4 0.7 2.1 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 GAM17063.1 - 0.00011 22.0 0.4 0.00022 21.0 0.4 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FAS_N PF17828.1 GAM17064.1 - 0.081 12.9 3.3 4.3 7.3 0.0 3.0 3 0 0 3 3 3 0 N-terminal domain in fatty acid synthase subunit beta RTP1_C1 PF10363.9 GAM17064.1 - 0.17 12.1 2.2 0.35 11.0 0.2 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 AA_permease_2 PF13520.6 GAM17065.1 - 1.3e-46 159.4 50.3 1.7e-46 159.0 50.3 1.2 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.11 GAM17065.1 - 2.7 8.1 10.7 10 6.3 2.5 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF962) Alpha-amylase PF00128.24 GAM17067.1 - 8.7e-55 186.6 0.0 1.7e-54 185.7 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 GAM17067.1 - 2.4e-05 22.8 0.4 0.0087 14.3 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 70 GHL6 PF14871.6 GAM17067.1 - 0.031 14.4 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 DUF1966 PF09260.11 GAM17067.1 - 0.043 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) DUF202 PF02656.15 GAM17068.1 - 4.7e-08 33.4 0.6 4.7e-08 33.4 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TALPID3 PF15324.6 GAM17068.1 - 0.29 8.7 2.3 0.34 8.5 2.3 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DUF872 PF05915.12 GAM17068.1 - 2.1 8.5 5.5 0.26 11.5 1.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3464 PF11947.8 GAM17068.1 - 6.3 6.5 8.4 0.46 10.2 3.0 1.9 2 1 0 2 2 2 0 Photosynthesis affected mutant 68 RNA_pol_I_A49 PF06870.12 GAM17069.1 - 5.7e-43 147.2 4.1 6.9e-43 147.0 4.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DHFR_1 PF00186.19 GAM17070.1 - 3.3e-19 69.2 0.0 5.4e-19 68.5 0.0 1.3 1 1 0 1 1 1 1 Dihydrofolate reductase RelA_SpoT PF04607.17 GAM17071.1 - 1.9e-26 92.6 0.0 3.8e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins CSG2 PF16965.5 GAM17071.1 - 0.11 11.4 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator LCM PF04072.14 GAM17073.1 - 1.6e-35 122.7 0.0 4.2e-35 121.4 0.0 1.6 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase CPBP PF02517.16 GAM17074.1 - 6.8e-16 58.4 10.8 6.8e-16 58.4 10.8 2.4 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease F-box-like PF12937.7 GAM17075.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like NTP_transferase PF00483.23 GAM17076.1 - 3.4e-06 26.8 0.0 7.9e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 GAM17076.1 - 4.9e-06 26.1 9.3 0.01 15.6 0.4 3.6 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Baculo_p24 PF05073.12 GAM17076.1 - 0.0017 18.2 0.3 0.0043 16.9 0.3 1.8 1 0 0 1 1 1 1 Baculovirus P24 capsid protein NTP_transf_3 PF12804.7 GAM17076.1 - 0.017 15.4 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain Phage_ABA_S PF18066.1 GAM17076.1 - 0.026 15.2 0.1 0.09 13.5 0.1 1.9 2 0 0 2 2 2 0 Phage ABA sandwich domain Fucokinase PF07959.12 GAM17076.1 - 0.032 13.2 1.1 0.046 12.7 1.1 1.2 1 0 0 1 1 1 0 L-fucokinase Creatininase PF02633.14 GAM17076.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Creatinine amidohydrolase Hexapep_2 PF14602.6 GAM17076.1 - 0.46 10.3 10.0 0.91 9.3 0.2 3.7 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase NUDIX PF00293.28 GAM17077.1 - 5.6e-20 71.7 0.0 6.5e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain LRR_6 PF13516.6 GAM17078.1 - 4.8e-40 132.2 45.3 2.7e-06 27.0 0.2 13.3 14 0 0 14 14 14 9 Leucine Rich repeat LRR_4 PF12799.7 GAM17078.1 - 0.0058 17.0 35.4 0.84 10.2 0.6 8.0 5 2 4 10 10 10 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM17078.1 - 0.028 14.9 22.1 33 5.6 0.0 9.8 10 2 0 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.6 GAM17078.1 - 0.39 10.5 40.9 1.2 8.9 0.4 9.1 5 3 4 9 9 9 0 Leucine rich repeat Methyltransf_2 PF00891.18 GAM17079.1 - 0.0033 16.7 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain FeoC PF09012.10 GAM17079.1 - 0.51 10.5 2.7 0.38 10.9 0.4 2.0 2 0 0 2 2 2 0 FeoC like transcriptional regulator Tox-MPTase4 PF15640.6 GAM17080.1 - 0.011 15.6 0.1 0.029 14.3 0.0 1.7 1 1 1 2 2 2 0 Metallopeptidase toxin 4 F-box PF00646.33 GAM17081.1 - 0.05 13.5 0.9 0.21 11.5 0.9 2.2 1 1 0 1 1 1 0 F-box domain UAA PF08449.11 GAM17083.1 - 5.6e-63 212.9 22.2 7.1e-63 212.6 22.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAM17083.1 - 1.3e-07 31.8 25.4 9.3e-05 22.6 13.4 3.0 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 GAM17083.1 - 8.1e-06 25.4 15.4 2.7e-05 23.7 11.2 2.1 1 1 1 2 2 2 2 Triose-phosphate Transporter family PIG-F PF06699.11 GAM17083.1 - 3.1 7.9 8.7 1.6 8.9 6.0 1.8 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F Peptidase_M20 PF01546.28 GAM17084.1 - 2.1e-31 109.2 0.0 3e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM17084.1 - 8e-12 45.0 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM17084.1 - 0.00087 19.0 0.0 0.0033 17.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Myb_DNA-binding PF00249.31 GAM17085.1 - 1.8e-15 56.9 0.1 1.1e-08 35.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM17085.1 - 1.2e-08 35.1 6.6 0.0012 19.0 1.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM17085.1 - 2.2e-05 24.2 1.4 2.2e-05 24.2 1.4 3.7 3 0 0 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 GAM17085.1 - 0.48 10.7 5.2 2.3 8.5 0.2 2.9 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Atrophin-1 PF03154.15 GAM17086.1 - 9.7e-06 24.2 11.0 1.2e-05 23.9 11.0 1.1 1 0 0 1 1 1 1 Atrophin-1 family Presenilin PF01080.17 GAM17086.1 - 6.7 5.4 6.3 7 5.3 6.3 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GAM17086.1 - 8.1 4.6 12.1 8.8 4.5 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 GAM17088.1 - 4.6e-73 245.8 0.0 8.1e-73 245.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17088.1 - 2.6e-34 118.7 0.0 4.2e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM17088.1 - 1.5e-11 44.2 0.0 1.1e-10 41.3 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 GAM17088.1 - 0.00013 21.7 0.1 0.00028 20.5 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAM17088.1 - 0.00016 21.1 0.1 0.00016 21.1 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 GAM17088.1 - 0.0014 18.2 0.3 0.0014 18.2 0.3 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Viral_env_E26 PF11050.8 GAM17088.1 - 0.014 14.7 1.5 0.11 11.8 0.1 2.7 3 0 0 3 3 3 0 Virus envelope protein E26 WD40 PF00400.32 GAM17090.1 - 8e-41 137.3 9.1 2.1e-08 34.7 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17090.1 - 5.7e-07 29.8 0.3 0.99 9.7 0.0 5.2 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM17090.1 - 0.001 18.5 0.0 0.064 12.6 0.0 3.1 2 1 1 3 3 3 2 WD40-like domain W_rich_C PF07483.11 GAM17090.1 - 0.015 15.5 0.8 1.6 8.9 0.1 3.4 3 0 0 3 3 3 0 Tryptophan-rich Synechocystis species C-terminal domain Med21 PF11221.8 GAM17090.1 - 0.064 13.5 1.4 0.12 12.7 1.4 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Ge1_WD40 PF16529.5 GAM17090.1 - 0.099 11.6 0.9 0.69 8.8 0.3 2.4 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein YmzC PF14157.6 GAM17090.1 - 1.8 8.7 4.5 8.1 6.6 0.1 3.0 3 0 0 3 3 3 0 YmzC-like protein AMP-binding PF00501.28 GAM17091.1 - 1.8e-24 86.2 0.0 2.3e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF543 PF04418.12 GAM17091.1 - 0.029 14.3 0.2 9.3 6.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) TNT PF14021.6 GAM17091.1 - 0.062 13.9 0.0 0.26 11.9 0.0 1.9 2 0 0 2 2 2 0 Tuberculosis necrotizing toxin 4HBT PF03061.22 GAM17092.1 - 9.3e-11 41.9 0.0 1.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 GAM17092.1 - 0.028 14.6 0.1 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 GAM17092.1 - 0.06 13.6 0.0 0.07 13.4 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily SUZ PF12752.7 GAM17093.1 - 9.2e-07 29.5 2.3 9.2e-07 29.5 2.3 4.3 2 1 1 3 3 3 1 SUZ domain Macoilin PF09726.9 GAM17093.1 - 2.2 6.7 11.8 2.6 6.5 11.8 1.1 1 0 0 1 1 1 0 Macoilin family Pex26 PF07163.12 GAM17094.1 - 6.5e-07 29.0 6.0 1.1e-05 24.9 5.9 2.2 1 1 0 1 1 1 1 Pex26 protein SUIM_assoc PF16619.5 GAM17094.1 - 0.54 10.4 8.4 1.6 8.9 8.4 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 GAM17095.1 - 4.1e-16 59.1 8.4 4.6e-05 24.1 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17095.1 - 7.7e-07 29.3 0.0 0.043 14.1 0.0 3.9 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM17095.1 - 0.0028 16.4 0.0 0.13 10.9 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 MIG-14_Wnt-bd PF06664.12 GAM17096.1 - 9.3e-65 218.7 30.7 2.2e-64 217.5 27.8 2.0 2 0 0 2 2 2 2 Wnt-binding factor required for Wnt secretion Myb_DNA-binding PF00249.31 GAM17097.1 - 1.3e-09 38.0 0.0 2.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM17097.1 - 0.0056 16.6 1.1 0.0056 16.6 1.1 2.1 2 0 0 2 2 2 1 Myb DNA-binding like Menin PF05053.13 GAM17097.1 - 0.013 13.9 5.8 0.019 13.4 5.8 1.3 1 0 0 1 1 1 0 Menin SLIDE PF09111.10 GAM17097.1 - 0.59 10.2 4.5 0.13 12.3 0.9 1.8 2 0 0 2 2 2 0 SLIDE DUF3362 PF11842.8 GAM17097.1 - 0.59 10.4 12.6 0.52 10.6 5.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) DUF2464 PF10240.9 GAM17097.1 - 8.7 5.8 11.1 15 5.0 8.1 2.3 2 0 0 2 2 2 0 Multivesicular body subunit 12 Ras PF00071.22 GAM17098.1 - 1.4e-38 132.0 0.0 1.6e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM17098.1 - 5.8e-24 84.6 0.0 8.4e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM17098.1 - 2.9e-11 43.1 0.0 3.2e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM17098.1 - 9.5e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 GAM17099.1 - 3.5e-41 140.5 0.2 4e-41 140.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM17099.1 - 2.1e-29 102.2 0.3 3e-29 101.7 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM17099.1 - 7.8e-15 54.8 0.1 9.1e-15 54.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM17099.1 - 2.7e-05 23.6 0.1 3.3e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM17099.1 - 0.00013 21.6 0.5 0.00073 19.1 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 GAM17099.1 - 0.0037 17.0 0.5 0.015 15.0 0.5 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 GAM17099.1 - 0.018 15.4 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 GAM17099.1 - 0.043 13.2 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 GAM17099.1 - 0.068 12.6 0.3 0.14 11.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Pex14_N PF04695.13 GAM17100.1 - 0.00067 20.3 0.9 0.00067 20.3 0.9 1.9 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region VIT1 PF01988.19 GAM17100.1 - 0.001 19.0 0.2 0.0022 17.9 0.1 1.5 1 1 0 1 1 1 1 VIT family NAM-associated PF14303.6 GAM17100.1 - 0.001 19.8 14.6 0.001 19.8 14.6 1.6 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain SR-25 PF10500.9 GAM17100.1 - 0.0043 16.7 11.9 0.0072 16.0 11.9 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Zip PF02535.22 GAM17100.1 - 0.037 13.3 5.5 0.045 13.0 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter AP-5_subunit_s1 PF15001.6 GAM17100.1 - 0.052 13.5 0.2 0.052 13.5 0.2 2.3 1 1 1 2 2 2 0 AP-5 complex subunit sigma-1 F420_oxidored PF03807.17 GAM17100.1 - 0.089 13.4 0.7 4.3 8.0 0.0 3.0 2 2 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent MASE3 PF17159.4 GAM17100.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated sensor domain Ndc1_Nup PF09531.10 GAM17100.1 - 0.16 10.6 0.7 0.16 10.7 0.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dsh_C PF12316.8 GAM17100.1 - 0.23 11.9 5.0 0.29 11.5 5.0 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Menin PF05053.13 GAM17100.1 - 0.28 9.5 11.2 0.37 9.1 11.2 1.1 1 0 0 1 1 1 0 Menin RR_TM4-6 PF06459.12 GAM17100.1 - 0.32 10.8 13.5 0.53 10.1 13.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3549 PF12069.8 GAM17100.1 - 0.54 9.2 6.9 0.67 8.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) Vma12 PF11712.8 GAM17100.1 - 1.1 9.3 9.0 5 7.2 8.6 2.3 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Dicty_REP PF05086.12 GAM17100.1 - 1.7 6.5 17.4 2.6 5.9 17.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Presenilin PF01080.17 GAM17100.1 - 1.9 7.2 16.1 2.9 6.6 16.1 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GAM17100.1 - 3.4 5.8 19.8 6 5.0 19.8 1.3 1 0 0 1 1 1 0 CDC45-like protein CLN3 PF02487.17 GAM17100.1 - 8.2 5.4 11.1 18 4.2 0.0 2.1 2 0 0 2 2 2 0 CLN3 protein NPR3 PF03666.13 GAM17101.1 - 3e-59 201.1 4.8 3.6e-34 118.4 0.0 2.0 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 GAM17101.1 - 0.00014 20.7 1.7 0.065 12.0 0.0 3.1 3 1 0 3 3 3 2 Nitrogen permease regulator 2 SR-25 PF10500.9 GAM17101.1 - 2.1 7.9 10.7 3.2 7.3 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Perilipin PF03036.16 GAM17102.1 - 0.00085 18.5 1.2 0.00085 18.5 1.2 3.2 2 1 1 3 3 3 1 Perilipin family REF PF05755.12 GAM17102.1 - 0.017 14.9 2.7 0.07 12.9 0.3 2.8 2 1 0 3 3 3 0 Rubber elongation factor protein (REF) Nbl1_Borealin_N PF10444.9 GAM17102.1 - 0.064 12.9 1.7 14 5.5 0.1 3.3 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF948 PF06103.11 GAM17102.1 - 0.96 9.8 4.7 4.1 7.7 0.5 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 GAM17103.1 - 5.7e-75 252.1 0.0 7.1e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17103.1 - 4.7e-47 160.4 0.0 6.3e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM17103.1 - 1.4e-08 34.5 0.0 5.1e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like R-HINP1I PF11463.8 GAM17103.1 - 0.00057 19.4 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 R.HinP1I restriction endonuclease Haspin_kinase PF12330.8 GAM17103.1 - 0.003 16.5 0.1 0.0084 15.1 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain SWIRM PF04433.17 GAM17103.1 - 0.012 15.9 0.1 0.035 14.4 0.0 1.7 2 0 0 2 2 2 0 SWIRM domain RIO1 PF01163.22 GAM17103.1 - 0.012 15.2 0.0 0.87 9.2 0.0 2.8 3 0 0 3 3 3 0 RIO1 family YrbL-PhoP_reg PF10707.9 GAM17103.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 GAM17103.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Hamartin PF04388.12 GAM17103.1 - 1.8 7.1 10.2 2.3 6.8 10.2 1.1 1 0 0 1 1 1 0 Hamartin protein Cpn10 PF00166.21 GAM17105.1 - 1.1e-23 83.1 0.1 1.2e-23 83.0 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit IL2 PF00715.17 GAM17106.1 - 0.051 13.5 3.5 0.43 10.5 0.4 2.3 2 0 0 2 2 2 0 Interleukin 2 Synaptobrevin PF00957.21 GAM17106.1 - 0.051 13.4 0.6 1.1 9.1 0.0 2.8 2 0 0 2 2 2 0 Synaptobrevin Guanylate_cyc PF00211.20 GAM17106.1 - 0.088 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Peptidase_S46 PF10459.9 GAM17106.1 - 0.17 10.5 5.1 0.24 10.0 5.1 1.1 1 0 0 1 1 1 0 Peptidase S46 PPR_2 PF13041.6 GAM17107.1 - 7.4e-48 160.5 12.6 2.8e-12 46.6 0.0 9.3 4 2 6 10 10 10 8 PPR repeat family GCV_H PF01597.19 GAM17107.1 - 2.8e-37 127.3 0.1 5.8e-37 126.3 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein PPR_1 PF12854.7 GAM17107.1 - 1.9e-36 123.4 11.8 9.9e-09 34.8 0.0 8.9 9 1 0 9 9 9 7 PPR repeat PPR PF01535.20 GAM17107.1 - 1.3e-34 116.0 23.3 6.4e-08 32.3 0.0 10.6 10 1 0 10 10 10 7 PPR repeat PPR_3 PF13812.6 GAM17107.1 - 2.5e-26 91.5 7.0 1.3e-06 28.4 0.0 6.5 4 2 2 7 7 7 6 Pentatricopeptide repeat domain PPR_long PF17177.4 GAM17107.1 - 5.3e-20 71.7 4.7 2e-07 30.6 0.6 3.8 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 GAM17107.1 - 8.3e-05 23.1 0.0 21 6.2 0.0 5.0 3 1 1 4 4 4 0 Tetratricopeptide repeat ATP13 PF12921.7 GAM17107.1 - 0.00052 19.9 0.3 0.36 10.7 0.0 3.8 2 1 2 4 4 4 1 Mitochondrial ATPase expression TPR_19 PF14559.6 GAM17107.1 - 0.0038 17.7 0.0 39 4.9 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Exog_C PF18026.1 GAM17107.1 - 0.045 13.8 0.1 0.75 9.9 0.0 3.1 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain SOBP PF15279.6 GAM17107.1 - 0.099 13.2 10.5 0.18 12.4 10.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein MBD_C PF14048.6 GAM17107.1 - 1.8 9.3 5.3 1.7 9.4 0.5 2.7 3 0 0 3 3 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Menin PF05053.13 GAM17107.1 - 7.2 4.8 10.7 12 4.0 10.7 1.3 1 0 0 1 1 1 0 Menin KxDL PF10241.9 GAM17108.1 - 0.022 15.0 6.2 0.022 15.0 6.2 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein Fib_alpha PF08702.10 GAM17108.1 - 0.071 13.3 20.4 0.53 10.5 1.7 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 GAM17108.1 - 0.15 10.0 10.4 0.19 9.6 10.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL14 PF03580.14 GAM17108.1 - 0.16 12.2 7.3 0.34 11.1 7.2 1.7 1 1 0 1 1 1 0 Herpesvirus UL14-like protein Spc7 PF08317.11 GAM17108.1 - 0.94 8.3 23.3 1.4 7.7 23.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 GAM17108.1 - 1.2 9.2 25.1 32 4.6 24.3 2.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 GAM17108.1 - 5.5 7.1 13.3 0.84 9.7 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cob_adeno_trans PF01923.18 GAM17108.1 - 5.6 7.1 7.2 5.1 7.2 5.6 1.9 1 1 0 1 1 1 0 Cobalamin adenosyltransferase CCDC53 PF10152.9 GAM17110.1 - 0.00076 19.9 0.7 0.001 19.5 0.7 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Allexi_40kDa PF05549.11 GAM17110.1 - 0.0085 15.6 0.1 0.0095 15.5 0.1 1.0 1 0 0 1 1 1 1 Allexivirus 40kDa protein NPV_P10 PF05531.12 GAM17110.1 - 0.07 13.6 0.4 0.2 12.2 0.1 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Fer4_24 PF18109.1 GAM17110.1 - 0.13 12.5 1.6 4 7.8 0.0 3.0 3 1 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain DUF4460 PF14687.6 GAM17111.1 - 1.7e-26 92.4 0.2 1.7e-26 92.4 0.2 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 GAM17111.1 - 2.8e-11 43.8 8.1 1.8e-10 41.1 0.0 3.0 2 1 0 3 3 3 2 Domain of unknown function (DUF4461) Ank_2 PF12796.7 GAM17112.1 - 0.049 14.2 0.0 1.4 9.5 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) DMA PF03474.14 GAM17112.1 - 0.099 12.3 0.1 5.7 6.6 0.0 3.5 4 0 0 4 4 4 0 DMRTA motif OST3_OST6 PF04756.13 GAM17114.1 - 5.3e-09 35.8 1.4 5.9e-09 35.7 1.4 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF202 PF02656.15 GAM17114.1 - 0.36 11.3 1.8 0.75 10.3 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Glyco_transf_10 PF00852.19 GAM17115.1 - 4e-37 127.7 0.2 8.3e-37 126.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 GAM17115.1 - 0.00045 20.6 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Presenilin PF01080.17 GAM17115.1 - 0.24 10.1 9.4 0.31 9.8 9.4 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 GAM17115.1 - 0.65 8.8 14.9 0.87 8.4 14.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 GAM17115.1 - 3.6 6.0 15.2 4.9 5.6 15.2 1.1 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 GAM17115.1 - 3.7 6.2 10.5 5.7 5.6 10.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EVI2A PF05399.11 GAM17115.1 - 7 6.2 8.7 12 5.4 8.7 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Ank_2 PF12796.7 GAM17116.1 - 5.9e-42 142.1 48.0 4.7e-10 39.9 1.1 7.0 2 1 9 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM17116.1 - 3.6e-33 113.5 18.4 6e-06 26.7 0.0 8.6 3 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM17116.1 - 5.3e-33 112.7 25.3 0.00015 22.0 0.0 12.2 4 2 8 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM17116.1 - 1.5e-15 55.7 15.2 3.9 8.3 0.0 12.2 11 3 3 14 14 14 5 Ankyrin repeat DUF5049 PF16468.5 GAM17116.1 - 2.9e-06 27.1 8.6 3.4 7.6 0.0 9.7 7 4 6 13 13 13 2 Domain of unknown function (DUF5049) Ank PF00023.30 GAM17116.1 - 0.00093 19.5 12.3 88 3.8 0.1 9.2 6 3 5 11 11 11 0 Ankyrin repeat DUF3734 PF12536.8 GAM17116.1 - 0.0038 17.5 0.3 6.5 7.2 0.0 4.8 5 2 1 6 6 6 1 Patatin phospholipase AhpC-TSA PF00578.21 GAM17116.1 - 0.031 14.2 0.1 8.1 6.4 0.0 4.4 4 2 2 6 6 6 0 AhpC/TSA family Ret2_MD PF18528.1 GAM17116.1 - 0.089 13.2 0.0 15 6.1 0.0 4.0 3 2 1 5 5 5 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Vps39_2 PF10367.9 GAM17117.1 - 5.7e-28 97.5 0.0 5.7e-28 97.5 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 GAM17117.1 - 5.8e-24 85.2 0.1 1.2e-23 84.2 0.1 1.5 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 GAM17117.1 - 1.6e-19 70.2 1.9 1.6e-19 70.2 1.9 3.6 4 1 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 GAM17117.1 - 2.1e-13 50.4 13.0 1.5e-07 31.4 1.9 4.3 4 1 0 4 4 4 2 Region in Clathrin and VPS DUF2175 PF09943.9 GAM17117.1 - 0.0029 17.9 1.2 0.017 15.4 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2175) DUF2944 PF11161.8 GAM17117.1 - 0.03 14.2 1.0 0.064 13.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) AhpC-TSA PF00578.21 GAM17117.1 - 0.064 13.2 0.3 0.89 9.5 0.0 2.6 2 0 0 2 2 2 0 AhpC/TSA family zinc_ribbon_9 PF14369.6 GAM17117.1 - 0.2 12.0 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 zinc-ribbon TPR_12 PF13424.6 GAM17117.1 - 0.85 9.9 6.1 6.8 7.1 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC2_membrane PF01061.24 GAM17118.1 - 5.3e-89 297.2 60.5 2.8e-49 167.4 22.0 2.9 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.27 GAM17118.1 - 1.9e-50 170.9 0.1 3.3e-24 86.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM17118.1 - 7.9e-08 32.0 0.3 0.0019 17.7 0.0 2.8 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 GAM17118.1 - 1.5e-07 31.6 0.0 0.012 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAM17118.1 - 1.6e-07 31.9 0.0 0.007 16.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM17118.1 - 1.7e-07 31.3 0.0 0.0016 18.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase PDR_CDR PF06422.12 GAM17118.1 - 4.8e-07 29.6 1.1 0.0014 18.4 0.1 2.8 2 0 0 2 2 2 2 CDR ABC transporter AAA_21 PF13304.6 GAM17118.1 - 2.4e-06 27.6 0.0 0.44 10.3 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 GAM17118.1 - 3.1e-06 27.2 0.1 0.36 10.7 0.0 4.2 5 0 0 5 5 5 2 Rad17 P-loop domain AAA_22 PF13401.6 GAM17118.1 - 8.2e-06 26.1 0.0 0.15 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAM17118.1 - 8.6e-06 26.3 0.0 0.24 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 GAM17118.1 - 1.1e-05 25.9 0.0 0.01 16.2 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAM17118.1 - 1.3e-05 24.8 0.0 0.022 14.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAM17118.1 - 2.5e-05 23.9 0.2 0.0039 16.9 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 GAM17118.1 - 0.00015 22.0 0.1 0.63 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAM17118.1 - 0.00022 21.6 0.0 0.96 9.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_17 PF13207.6 GAM17118.1 - 0.00045 20.7 0.0 0.17 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAM17118.1 - 0.00096 18.9 0.1 1.2 8.8 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein DUF815 PF05673.13 GAM17118.1 - 0.0013 17.9 0.4 0.019 14.1 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 GAM17118.1 - 0.0016 18.4 0.5 0.28 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 GAM17118.1 - 0.0022 17.3 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 GAM17118.1 - 0.0023 17.9 0.2 1.8 8.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 GAM17118.1 - 0.0026 17.8 0.1 1.1 9.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 GAM17118.1 - 0.0035 16.9 0.1 0.27 10.7 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 GAM17118.1 - 0.004 17.4 0.0 0.7 10.2 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 GAM17118.1 - 0.0042 16.8 0.1 2.6 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 GAM17118.1 - 0.008 16.2 0.5 1.6 8.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 GAM17118.1 - 0.0086 16.3 0.0 3.7 7.8 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 GAM17118.1 - 0.0093 16.5 0.5 1.5 9.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 GAM17118.1 - 0.013 15.0 0.1 3.3 7.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 GAM17118.1 - 0.089 12.5 0.3 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 GAM17118.1 - 0.11 12.4 0.0 14 5.5 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 GAM17118.1 - 0.13 11.9 0.1 9 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAM17118.1 - 0.15 11.7 0.2 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 GAM17118.1 - 0.18 12.2 0.3 2.1 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAM17118.1 - 0.21 10.8 0.2 14 4.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PDR_assoc PF08370.11 GAM17118.1 - 0.4 10.5 13.0 0.35 10.7 0.5 3.5 3 0 0 3 3 2 0 Plant PDR ABC transporter associated Mg_chelatase PF01078.21 GAM17118.1 - 0.42 10.0 1.5 3.6 6.9 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC2_membrane_3 PF12698.7 GAM17118.1 - 0.53 9.3 59.3 0.068 12.3 25.1 3.4 2 2 0 2 2 2 0 ABC-2 family transporter protein XRCC1_N PF01834.16 GAM17119.1 - 6.8e-45 152.7 0.2 6.8e-45 152.7 0.2 2.2 2 0 0 2 2 2 1 XRCC1 N terminal domain BRCT_2 PF16589.5 GAM17119.1 - 7.1e-14 52.0 3.1 4.3e-08 33.5 0.1 3.5 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAM17119.1 - 2.7e-10 40.5 0.0 0.0012 19.2 0.0 3.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 GAM17119.1 - 3.6e-07 30.4 0.0 0.002 18.4 0.0 3.1 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 GAM17119.1 - 8.6e-05 22.4 0.0 0.00034 20.5 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain HUN PF08729.10 GAM17119.1 - 4.5 7.3 16.5 4.9 7.2 9.7 2.8 2 0 0 2 2 2 0 HPC2 and ubinuclein domain ADH_zinc_N PF00107.26 GAM17120.1 - 1.4e-28 99.5 0.0 2.1e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM17120.1 - 3.2e-20 73.5 0.0 6.9e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM17120.1 - 4.6e-09 36.1 0.0 8.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 GAM17120.1 - 0.00035 20.1 0.1 0.00064 19.2 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_N_2 PF16884.5 GAM17120.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TrkA_N PF02254.18 GAM17120.1 - 0.055 13.7 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 GAM17120.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Alpha_kinase PF02816.18 GAM17121.1 - 7.9e-57 192.4 0.2 1.5e-56 191.4 0.2 1.5 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.32 GAM17121.1 - 2e-17 63.2 12.8 0.0078 17.1 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat WD40_like PF17005.5 GAM17121.1 - 2e-09 37.2 1.2 1.1e-08 34.8 1.2 1.9 1 1 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 GAM17121.1 - 3.9e-07 29.1 8.0 0.00079 18.2 0.7 3.0 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 GAM17121.1 - 0.0042 15.7 0.1 0.94 7.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF1513 PF07433.11 GAM17121.1 - 0.021 13.9 0.2 5 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Ge1_WD40 PF16529.5 GAM17121.1 - 0.059 12.3 5.7 0.99 8.3 0.6 2.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HPS3_N PF14761.6 GAM17121.1 - 0.12 11.9 0.3 6.5 6.2 0.1 2.7 1 1 2 3 3 3 0 Hermansky-Pudlak syndrome 3 GST_C_3 PF14497.6 GAM17122.1 - 7.1e-20 71.0 0.1 1e-19 70.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM17122.1 - 3.4e-06 27.2 0.0 4.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM17122.1 - 4.4e-06 27.0 0.0 1.3e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM17122.1 - 0.00078 19.4 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAM17122.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FNIP PF05725.12 GAM17124.1 - 5.3e-70 231.4 18.2 1.1e-11 44.6 0.1 9.4 9 0 0 9 9 9 8 FNIP Repeat Polysacc_deac_1 PF01522.21 GAM17125.1 - 5.7e-23 81.2 0.1 1.8e-20 73.1 0.0 2.6 2 0 0 2 2 2 2 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 GAM17125.1 - 0.021 14.0 1.0 0.063 12.5 0.0 2.2 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase Presenilin PF01080.17 GAM17125.1 - 0.043 12.6 4.4 2.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Presenilin FAM60A PF15396.6 GAM17125.1 - 0.55 10.2 10.8 0.28 11.2 0.8 2.3 2 0 0 2 2 2 0 Protein Family FAM60A DUF4112 PF13430.6 GAM17127.1 - 0.094 13.0 0.0 0.86 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) Glyco_hydro_20b PF02838.15 GAM17127.1 - 0.14 12.9 0.3 0.32 11.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 DUF4698 PF15769.5 GAM17129.1 - 0.011 14.8 3.3 0.017 14.3 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Sialidase PF02973.16 GAM17132.1 - 0.035 13.6 0.9 0.054 13.0 0.4 1.5 2 0 0 2 2 2 0 Sialidase, N-terminal domain Toprim_Crpt PF13342.6 GAM17134.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase Ank_3 PF13606.6 GAM17137.1 - 0.00045 20.5 0.6 4.8 8.1 0.1 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ank_2 PF12796.7 GAM17137.1 - 0.06 13.9 0.6 28 5.4 0.1 3.9 3 3 1 4 4 4 0 Ankyrin repeats (3 copies) DEAD PF00270.29 GAM17139.1 - 8.4e-22 77.8 0.9 1.3e-21 77.2 0.9 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM17139.1 - 1.2e-16 61.1 0.0 1.2e-15 57.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 GAM17139.1 - 0.028 13.2 0.0 0.087 11.6 0.0 1.7 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ketoacyl-synt PF00109.26 GAM17140.1 - 4.4e-77 259.1 2.3 4.6e-76 255.7 0.0 3.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAM17140.1 - 6.2e-56 190.2 0.0 1.4e-55 189.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAM17140.1 - 3.3e-45 154.6 0.0 1.2e-44 152.8 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.10 GAM17140.1 - 5.1e-40 137.3 1.4 1.6e-39 135.7 0.9 2.2 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 GAM17140.1 - 1.5e-32 112.1 0.2 6e-32 110.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Chal_sti_synt_C PF02797.15 GAM17140.1 - 2e-23 83.1 0.1 4.7e-23 81.9 0.1 1.7 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ADH_zinc_N PF00107.26 GAM17140.1 - 8.4e-19 67.8 0.0 6.2e-18 65.0 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Chal_sti_synt_N PF00195.19 GAM17140.1 - 5e-17 62.1 0.3 1.7e-16 60.3 0.3 1.9 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ADH_zinc_N_2 PF13602.6 GAM17140.1 - 1.2e-15 58.7 0.0 8e-15 56.1 0.0 2.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAE1_CUT1_RppA PF08392.12 GAM17140.1 - 5.8e-13 48.8 0.3 5.8e-13 48.8 0.3 1.7 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein KAsynt_C_assoc PF16197.5 GAM17140.1 - 2.1e-10 41.0 0.1 9.2e-10 39.0 0.1 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 GAM17140.1 - 1.2e-08 35.1 0.1 3.1e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 GAM17140.1 - 5.5e-08 32.7 0.1 1.4e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 GAM17140.1 - 2.4e-07 30.8 0.7 8e-05 22.7 0.0 3.7 3 0 0 3 3 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal adh_short PF00106.25 GAM17140.1 - 8.4e-07 28.6 5.4 1.1e-06 28.3 1.8 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 GAM17140.1 - 4.9e-05 22.8 0.1 4.9e-05 22.8 0.1 4.0 4 0 0 4 4 4 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 GAM17140.1 - 0.00028 20.7 8.9 0.0016 18.3 0.6 3.7 3 1 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3130 PF11328.8 GAM17140.1 - 0.16 12.2 1.3 8.4 6.7 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 Trp_halogenase PF04820.14 GAM17141.1 - 3.1e-10 39.5 0.0 3.5e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.24 GAM17141.1 - 9.3e-05 22.2 0.1 0.00016 21.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM17141.1 - 0.0076 15.5 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAM17141.1 - 0.0083 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAM17141.1 - 0.012 14.8 0.1 0.029 13.6 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 GAM17141.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAM17141.1 - 0.031 13.4 0.7 0.58 9.2 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAM17141.1 - 0.063 13.5 0.1 0.2 11.9 0.1 1.9 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAM17141.1 - 0.11 11.7 0.0 5.8 6.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 GAM17141.1 - 0.18 10.8 0.8 0.3 10.1 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain RRM_1 PF00076.22 GAM17142.1 - 2.1e-05 24.2 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S8 PF00082.22 GAM17144.1 - 6.6e-40 137.2 8.9 9.6e-40 136.7 8.9 1.2 1 0 0 1 1 1 1 Subtilase family DUF3188 PF11384.8 GAM17144.1 - 0.66 9.7 4.1 0.63 9.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Metallophos PF00149.28 GAM17146.1 - 3.3e-12 47.4 1.2 6.1e-12 46.5 1.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SapB_2 PF03489.17 GAM17146.1 - 0.017 15.3 3.6 0.021 14.9 0.4 2.8 3 0 0 3 3 3 0 Saposin-like type B, region 2 Rad1 PF02144.16 GAM17148.1 - 7.8e-49 166.2 0.4 1.5e-48 165.3 0.4 1.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 GAM17148.1 - 0.0051 16.0 0.0 0.4 9.7 0.0 2.1 1 1 1 2 2 2 2 Hus1-like protein Pkinase PF00069.25 GAM17149.1 - 5.4e-45 153.8 0.0 5.4e-45 153.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17149.1 - 2.1e-21 76.4 0.0 5e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PS_Dcarbxylase PF02666.15 GAM17150.1 - 6.4e-61 205.4 0.0 8.9e-61 204.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Inhibitor_I71 PF12628.7 GAM17150.1 - 0.021 14.6 0.4 0.021 14.6 0.4 2.2 3 0 0 3 3 3 0 Falstatin, cysteine peptidase inhibitor SprA-related PF12118.8 GAM17150.1 - 0.033 13.4 10.7 0.045 12.9 10.7 1.1 1 0 0 1 1 1 0 SprA-related family DUF3464 PF11947.8 GAM17150.1 - 0.21 11.3 1.4 0.45 10.3 1.4 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Spt20 PF12090.8 GAM17150.1 - 0.39 10.3 14.1 0.64 9.6 14.1 1.4 1 0 0 1 1 1 0 Spt20 family DUF5336 PF17270.2 GAM17150.1 - 0.44 10.2 1.2 0.72 9.5 1.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Serinc PF03348.15 GAM17150.1 - 0.91 8.4 2.2 1.2 8.0 2.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 GAM17150.1 - 1.9 7.2 5.0 2.6 6.7 5.0 1.1 1 0 0 1 1 1 0 Presenilin DUF898 PF05987.13 GAM17151.1 - 0.065 12.3 13.4 0.078 12.0 11.7 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF4554 PF15091.6 GAM17151.1 - 0.42 9.4 6.0 0.63 8.9 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Arv1 PF04161.13 GAM17151.1 - 1.5 8.9 5.5 6.6 6.8 5.5 2.1 1 1 0 1 1 1 0 Arv1-like family DUF373 PF04123.13 GAM17151.1 - 6.2 6.2 15.8 0.28 10.6 8.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF373) cNMP_binding PF00027.29 GAM17152.1 - 4e-45 151.8 0.0 1e-22 80.0 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 7TMR-HDED PF07697.11 GAM17152.1 - 0.0043 17.2 0.1 0.42 10.7 0.1 2.3 2 0 0 2 2 2 1 7TM-HD extracellular Cupin_3 PF05899.12 GAM17152.1 - 0.011 15.4 1.0 0.059 13.1 0.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF861) SSV1_ORF_D-335 PF07935.11 GAM17152.1 - 0.12 12.7 3.4 4 7.8 0.1 3.3 3 0 0 3 3 3 0 ORF D-335-like protein DUF3196 PF11428.8 GAM17152.1 - 0.12 11.8 0.3 16 4.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3196) Cupin_2 PF07883.11 GAM17152.1 - 0.21 11.4 3.5 0.25 11.1 0.2 2.6 3 1 0 3 3 3 0 Cupin domain Adaptin_N PF01602.20 GAM17153.1 - 1.9e-126 422.7 17.3 2.6e-126 422.3 17.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAM17153.1 - 6.1e-12 45.9 7.6 2.8e-10 40.5 0.4 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 AP3D1 PF06375.11 GAM17153.1 - 4.8e-09 36.7 4.9 0.00042 20.6 0.3 2.8 1 1 1 2 2 2 2 AP-3 complex subunit delta-1 RTP1_C1 PF10363.9 GAM17153.1 - 0.0005 20.2 1.0 1.2 9.4 0.4 3.4 2 1 1 3 3 3 3 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 GAM17153.1 - 0.0012 18.9 6.9 2.8 8.5 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat NPCBM_assoc PF10633.9 GAM17153.1 - 0.0059 16.8 0.2 0.015 15.5 0.2 1.7 1 0 0 1 1 1 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Alpha_adaptinC2 PF02883.20 GAM17153.1 - 0.021 15.1 0.3 0.056 13.7 0.3 1.7 1 0 0 1 1 1 0 Adaptin C-terminal domain RasGEF_N_2 PF14663.6 GAM17153.1 - 0.045 14.1 0.1 6 7.3 0.1 3.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FixG_C PF11614.8 GAM17153.1 - 0.09 13.0 1.5 0.28 11.4 0.2 2.5 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Tti2 PF10521.9 GAM17153.1 - 1.4 8.4 7.7 0.34 10.4 0.2 3.1 4 0 0 4 4 4 0 Tti2 family E1-E2_ATPase PF00122.20 GAM17154.1 - 6.1e-50 169.2 6.6 7.2e-50 169.0 2.9 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAM17154.1 - 3.6e-19 69.9 0.1 8.6e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM17154.1 - 1.7e-14 53.3 0.0 3.3e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM17154.1 - 0.00074 19.3 0.6 0.002 17.9 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM17154.1 - 0.0015 18.6 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Myosin_head PF00063.21 GAM17155.1 - 9e-258 857.0 2.8 9e-258 857.0 2.8 3.9 3 2 0 3 3 3 1 Myosin head (motor domain) DIL PF01843.19 GAM17155.1 - 2.8e-17 62.9 0.0 2.8e-17 62.9 0.0 5.5 4 1 1 5 5 5 1 DIL domain IQ PF00612.27 GAM17155.1 - 6.6e-17 59.7 30.3 3.2e-06 26.5 0.5 6.6 6 0 0 6 6 6 5 IQ calmodulin-binding motif Myosin_N PF02736.19 GAM17155.1 - 0.0011 18.8 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF1664 PF07889.12 GAM17155.1 - 0.0065 16.5 6.2 0.0065 16.5 6.2 11.2 2 2 9 12 12 12 3 Protein of unknown function (DUF1664) AAA_16 PF13191.6 GAM17155.1 - 0.055 13.8 0.0 0.055 13.8 0.0 4.4 5 1 0 5 5 5 0 AAA ATPase domain AAA_22 PF13401.6 GAM17155.1 - 0.25 11.6 0.0 0.25 11.6 0.0 4.5 5 0 0 5 5 5 0 AAA domain Metallothi_Euk2 PF12809.7 GAM17156.1 - 4 7.8 11.3 13 6.2 3.5 2.6 2 0 0 2 2 2 0 Eukaryotic metallothionein DSPc PF00782.20 GAM17158.1 - 4.5e-08 33.0 0.0 3.6e-07 30.1 0.0 2.4 1 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 GAM17158.1 - 0.0017 18.3 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Pkinase PF00069.25 GAM17159.1 - 7.9e-73 245.1 0.0 1.1e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17159.1 - 4.2e-33 114.7 0.0 6.1e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM17159.1 - 0.00025 20.5 0.0 0.0038 16.6 0.0 2.1 1 1 0 2 2 2 1 Kinase-like TFIIA PF03153.13 GAM17159.1 - 0.012 15.7 9.3 0.015 15.4 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Haspin_kinase PF12330.8 GAM17159.1 - 0.053 12.5 3.8 0.095 11.6 3.8 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Androgen_recep PF02166.16 GAM17159.1 - 6.2 5.5 11.2 9.3 5.0 11.2 1.2 1 0 0 1 1 1 0 Androgen receptor GFO_IDH_MocA PF01408.22 GAM17160.1 - 3.4e-23 82.7 0.1 5.3e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAM17160.1 - 4.5e-08 33.1 0.0 1.5e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Kelch_6 PF13964.6 GAM17161.1 - 4.9e-13 48.8 2.8 0.00075 19.7 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 GAM17161.1 - 5.2e-07 29.6 5.1 0.0075 16.3 0.1 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM17161.1 - 0.0072 16.3 0.9 0.6 10.2 0.0 3.4 2 1 1 3 3 3 1 Kelch motif Kelch_1 PF01344.25 GAM17161.1 - 0.08 12.5 3.2 6.2 6.5 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 GAM17161.1 - 0.15 12.1 5.2 14 5.8 0.8 3.4 3 0 0 3 3 3 0 Kelch motif HAP2-GCS1 PF10699.9 GAM17162.1 - 7.1e-13 48.3 0.1 1.5e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 Male gamete fusion factor TIG PF01833.24 GAM17163.1 - 5.6e-22 77.6 59.0 4.6e-07 29.8 5.1 8.4 7 2 1 8 8 8 7 IPT/TIG domain DUF4448 PF14610.6 GAM17163.1 - 0.03 14.1 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) HCBP_related PF06594.11 GAM17163.1 - 0.046 13.7 1.8 7.2 6.6 0.0 4.3 4 0 0 4 4 4 0 Haemolysin-type calcium binding protein related domain PilN PF05137.13 GAM17163.1 - 0.05 13.7 4.0 8.1 6.7 0.0 4.7 5 0 0 5 5 5 0 Fimbrial assembly protein (PilN) YabP PF07873.11 GAM17163.1 - 0.2 11.4 3.4 22 4.9 0.1 3.9 4 0 0 4 4 4 0 YabP family SLT PF01464.20 GAM17164.1 - 3.1e-10 39.7 0.0 5.9e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 GAM17164.1 - 0.0015 18.8 4.0 0.019 15.2 4.0 2.1 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family PALP PF00291.25 GAM17165.1 - 1.9e-71 240.9 0.0 2.1e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 GAM17165.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Ribosomal_S7e PF01251.18 GAM17166.1 - 3.6e-77 258.3 4.7 4.1e-77 258.1 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e PAP1 PF08601.10 GAM17167.1 - 0.047 13.4 18.4 0.055 13.2 18.4 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Presenilin PF01080.17 GAM17167.1 - 8.6 5.0 7.2 9.7 4.8 7.2 1.3 1 0 0 1 1 1 0 Presenilin SAM_MT PF04445.13 GAM17168.1 - 9.9e-44 149.5 0.0 1.5e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Milton PF12448.8 GAM17168.1 - 0.048 13.8 2.4 0.079 13.1 0.2 2.0 2 0 0 2 2 2 0 Kinesin associated protein Methyltransf_23 PF13489.6 GAM17168.1 - 0.06 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ubiquitin PF00240.23 GAM17170.1 - 1.4e-163 530.9 39.7 1.3e-32 111.3 0.6 8.0 6 2 2 8 8 8 8 Ubiquitin family Rad60-SLD PF11976.8 GAM17170.1 - 9.1e-72 236.9 31.4 9.6e-15 54.2 0.6 8.0 6 2 2 8 8 8 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAM17170.1 - 5e-25 87.8 13.3 0.0011 19.4 0.1 7.5 6 4 0 6 6 6 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM17170.1 - 1.7e-16 60.3 4.0 0.28 11.3 0.0 6.3 6 3 0 6 6 6 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAM17170.1 - 5.1e-16 58.8 11.5 0.04 14.3 0.1 5.4 5 1 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 GAM17170.1 - 2.3e-14 53.1 5.8 0.091 12.7 0.0 5.2 5 0 0 5 5 5 4 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 GAM17170.1 - 4.2e-14 53.0 1.8 0.86 10.2 0.0 5.3 1 1 0 5 5 5 4 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 GAM17170.1 - 7.5e-09 35.3 4.2 2.7 7.3 0.0 5.1 5 0 0 5 5 5 4 RNA methyltransferase UDP-g_GGTase PF06427.11 GAM17170.1 - 4.9e-08 33.0 7.3 5.9 7.0 0.0 5.7 5 1 1 6 6 6 1 UDP-glucose:Glycoprotein Glucosyltransferase DUF2870 PF11069.8 GAM17170.1 - 3.2e-07 30.6 0.0 45 4.5 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 GAM17170.1 - 2e-06 27.7 27.8 34 4.6 0.0 10.2 10 2 1 11 11 11 0 Ubiquitin-like domain Big_3_3 PF13750.6 GAM17170.1 - 3.9e-06 26.6 0.2 31 4.2 0.0 5.6 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) ORF11CD3 PF10549.9 GAM17170.1 - 2.4e-05 24.4 0.5 1.4e+02 2.7 0.0 6.8 10 0 0 10 10 6 0 ORF11CD3 domain DUF969 PF06149.12 GAM17170.1 - 7.3e-05 22.3 0.2 32 3.9 0.0 5.2 6 0 0 6 6 6 0 Protein of unknown function (DUF969) DUF3861 PF12977.7 GAM17170.1 - 0.0004 20.5 2.1 49 4.2 0.0 4.6 5 0 0 5 5 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 GAM17170.1 - 0.00067 20.4 0.6 1.7e+02 3.1 0.0 5.3 6 0 0 6 6 6 0 Bacterial Ig domain ACT_5 PF13710.6 GAM17170.1 - 0.0014 18.4 6.5 63 3.5 0.0 5.9 6 0 0 6 6 6 0 ACT domain DUF3435 PF11917.8 GAM17170.1 - 0.0017 17.4 0.6 33 3.2 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3435) YcgR_2 PF12945.7 GAM17170.1 - 0.0039 17.3 6.6 45 4.3 0.1 4.8 4 0 0 4 4 4 0 Flagellar protein YcgR Corona_NS2A PF05213.12 GAM17170.1 - 0.0046 16.3 0.2 68 2.7 0.0 4.1 4 0 0 4 4 4 0 Coronavirus NS2A protein MoaF PF10703.9 GAM17170.1 - 0.0068 16.3 4.0 43 4.1 0.0 5.8 6 0 0 6 6 6 0 MoaF N-terminal domain Imm12 PF15560.6 GAM17170.1 - 0.0079 16.2 5.6 1.1e+02 2.7 0.0 5.6 6 0 0 6 6 6 0 Immunity protein 12 Plug_translocon PF10559.9 GAM17170.1 - 0.017 15.0 0.0 12 5.8 0.0 4.4 5 0 0 5 5 5 0 Plug domain of Sec61p ACT_4 PF13291.6 GAM17170.1 - 0.024 15.2 0.4 2.8e+02 2.2 0.0 4.5 4 0 0 4 4 4 0 ACT domain NEAT PF05031.12 GAM17170.1 - 0.27 11.9 8.6 1.6e+02 2.9 4.0 4.6 1 1 0 2 2 2 0 Iron Transport-associated domain Myosin_N PF02736.19 GAM17170.1 - 0.74 9.7 15.1 1.6e+02 2.2 0.0 7.5 6 1 1 7 7 7 0 Myosin N-terminal SH3-like domain bPH_3 PF14470.6 GAM17170.1 - 1.1 9.7 15.0 15 6.0 0.1 5.7 6 1 1 7 7 7 0 Bacterial PH domain PH_15 PF17339.2 GAM17170.1 - 1.2 9.1 10.6 1.4e+02 2.5 0.1 5.1 4 2 1 5 5 5 0 PH domain ProRS-C_2 PF09181.10 GAM17170.1 - 4.6 7.4 5.7 2.9e+02 1.7 0.1 4.0 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Choline_transpo PF04515.12 GAM17171.1 - 1e-100 337.1 35.3 1e-100 337.1 35.3 2.1 1 1 1 2 2 2 1 Plasma-membrane choline transporter DUF543 PF04418.12 GAM17171.1 - 6.2 6.9 9.6 18 5.4 3.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF543) NUDIX PF00293.28 GAM17172.1 - 3.2e-08 33.7 0.0 7.4e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain NIPSNAP PF07978.13 GAM17173.1 - 7.6e-42 141.7 0.0 6.5e-22 77.7 0.1 2.0 2 0 0 2 2 2 2 NIPSNAP HALZ PF02183.18 GAM17175.1 - 0.00023 21.3 0.2 0.00067 19.8 0.0 1.8 1 1 1 2 2 2 1 Homeobox associated leucine zipper Cnn_1N PF07989.11 GAM17175.1 - 0.00054 20.1 2.3 0.00078 19.6 2.1 1.7 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 DivIC PF04977.15 GAM17175.1 - 0.0042 16.8 0.6 0.0042 16.8 0.6 1.5 2 0 0 2 2 2 1 Septum formation initiator DUF1640 PF07798.11 GAM17175.1 - 0.0042 17.1 0.5 0.0078 16.3 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Phasin PF05597.11 GAM17175.1 - 0.0063 16.5 0.8 0.0066 16.5 0.8 1.3 1 1 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) bZIP_1 PF00170.21 GAM17175.1 - 0.0063 16.6 0.8 0.0063 16.6 0.8 1.6 2 0 0 2 2 2 1 bZIP transcription factor Seryl_tRNA_N PF02403.22 GAM17175.1 - 0.0077 16.4 1.7 0.0091 16.2 1.7 1.1 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 GAM17175.1 - 0.0079 16.2 0.7 0.0079 16.2 0.7 1.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 GAM17175.1 - 0.013 13.5 0.3 0.014 13.4 0.3 1.0 1 0 0 1 1 1 0 Prominin Shugoshin_N PF07558.11 GAM17175.1 - 0.017 15.0 0.2 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Spc7 PF08317.11 GAM17175.1 - 0.023 13.6 1.3 0.024 13.5 1.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Matrilin_ccoil PF10393.9 GAM17175.1 - 0.025 14.4 0.8 0.046 13.6 0.4 1.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin ZapB PF06005.12 GAM17175.1 - 0.027 14.9 2.0 0.027 14.9 2.0 1.8 1 1 1 2 2 2 0 Cell division protein ZapB CdvA PF18822.1 GAM17175.1 - 0.03 14.2 3.4 0.041 13.7 0.9 2.0 1 1 1 2 2 2 0 CdvA-like coiled-coil domain JIP_LZII PF16471.5 GAM17175.1 - 0.034 14.3 1.5 0.067 13.4 1.5 1.6 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II SF-assemblin PF06705.11 GAM17175.1 - 0.037 13.4 1.4 0.042 13.2 1.4 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin FlaC_arch PF05377.11 GAM17175.1 - 0.051 14.0 1.2 0.24 11.8 0.1 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 GAM17175.1 - 0.055 13.6 0.6 0.11 12.6 0.6 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Vps39_1 PF10366.9 GAM17175.1 - 0.059 13.6 0.1 0.064 13.6 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 DUF730 PF05325.11 GAM17175.1 - 0.094 12.7 0.1 0.12 12.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF730) AAA PF00004.29 GAM17177.1 - 5.4e-45 153.1 0.0 1.7e-44 151.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM17177.1 - 3.1e-10 39.7 0.0 8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAM17177.1 - 8.2e-09 35.6 0.1 2.5e-08 34.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 GAM17177.1 - 1.2e-07 31.6 0.1 3.8e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 GAM17177.1 - 1.4e-07 32.0 0.2 4.8e-05 23.8 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 GAM17177.1 - 2.2e-07 31.2 0.0 4.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAM17177.1 - 2.8e-05 24.4 1.5 0.0068 16.7 0.1 3.1 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 GAM17177.1 - 6.1e-05 22.8 0.0 0.00021 21.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 GAM17177.1 - 8.5e-05 21.8 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 GAM17177.1 - 0.0004 20.9 0.0 0.001 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 GAM17177.1 - 0.00043 19.6 0.0 0.00075 18.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 GAM17177.1 - 0.00072 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAM17177.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAM17177.1 - 0.0015 17.9 0.0 0.0035 16.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAM17177.1 - 0.0016 18.8 0.0 0.0041 17.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.26 GAM17177.1 - 0.0016 18.2 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 GAM17177.1 - 0.0028 17.7 0.0 0.0095 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 GAM17177.1 - 0.0038 17.2 0.0 0.0088 16.0 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAM17177.1 - 0.0052 16.3 0.1 0.041 13.4 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 GAM17177.1 - 0.0078 16.1 0.0 0.097 12.6 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.6 GAM17177.1 - 0.0085 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GAM17177.1 - 0.0091 15.6 0.6 0.035 13.7 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 GAM17177.1 - 0.01 15.5 0.1 0.027 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GAM17177.1 - 0.011 15.7 0.1 0.071 13.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 GAM17177.1 - 0.011 15.5 0.0 0.036 13.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAM17177.1 - 0.016 15.0 0.1 0.036 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 GAM17177.1 - 0.018 14.1 0.0 0.044 12.9 0.0 1.6 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 TniB PF05621.11 GAM17177.1 - 0.021 14.3 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Viral_Hsp90 PF03225.14 GAM17177.1 - 0.025 13.1 0.1 0.037 12.6 0.1 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue NB-ARC PF00931.22 GAM17177.1 - 0.031 13.5 0.1 0.41 9.8 0.0 2.4 3 0 0 3 3 2 0 NB-ARC domain ATPase PF06745.13 GAM17177.1 - 0.074 12.4 0.7 0.48 9.7 0.0 2.3 3 0 0 3 3 3 0 KaiC Rab5ip PF07019.12 GAM17178.1 - 1.7e-14 54.1 4.5 2.4e-14 53.7 4.5 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Peptidase_U40 PF10464.9 GAM17178.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase U40 UPF0449 PF15136.6 GAM17179.1 - 2.6e-05 24.6 1.3 3.5e-05 24.2 0.3 1.7 1 1 1 2 2 2 1 Uncharacterised protein family UPF0449 BSP PF04450.12 GAM17179.1 - 0.03 14.1 0.2 0.046 13.5 0.2 1.3 1 1 0 1 1 1 0 Peptidase of plants and bacteria DUF573 PF04504.14 GAM17179.1 - 0.046 14.4 0.7 0.058 14.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Cyclin PF08613.11 GAM17180.1 - 0.00017 22.0 0.8 0.00017 22.0 0.8 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAM17180.1 - 0.00019 21.2 0.5 0.00019 21.2 0.5 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Response_reg PF00072.24 GAM17181.1 - 2.1e-35 121.3 0.9 3.1e-27 94.9 0.6 3.7 3 0 0 3 3 3 3 Response regulator receiver domain HATPase_c PF02518.26 GAM17181.1 - 4.1e-27 94.9 0.1 1.8e-26 92.8 0.1 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAM17181.1 - 1.7e-16 60.0 0.2 5.8e-16 58.3 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 GAM17181.1 - 2e-09 37.6 0.0 2.5e-08 34.1 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 GAM17181.1 - 1.4e-05 25.0 0.0 0.00011 22.2 0.0 2.4 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 GAM17181.1 - 2e-05 24.8 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 GAM17181.1 - 4.5e-05 23.7 0.0 0.00012 22.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold Tubulin_2 PF13809.6 GAM17182.1 - 1 8.5 2.8 1.1 8.4 2.8 1.0 1 0 0 1 1 1 0 Tubulin like Coiled PF05710.12 GAM17182.1 - 1.1 10.1 11.3 2.6 9.0 11.3 1.6 1 1 0 1 1 1 0 Coiled coil SIP1 PF04938.12 GAM17183.1 - 1e-70 237.9 0.1 1.1e-70 237.7 0.1 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Chlam_PMP PF02415.17 GAM17184.1 - 0.078 13.5 57.8 0.46 11.1 0.2 9.9 10 1 0 10 10 10 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat CBF PF03914.17 GAM17185.1 - 6.7e-41 140.2 1.4 2.4e-40 138.3 0.3 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.20 GAM17185.1 - 0.0043 15.7 12.1 0.029 12.9 1.4 2.6 2 1 1 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.6 GAM17185.1 - 0.013 15.9 0.2 0.39 11.1 0.1 3.1 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 GAM17185.1 - 0.11 12.8 0.1 0.65 10.4 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat Cnd1 PF12717.7 GAM17185.1 - 0.17 11.9 6.4 0.24 11.4 1.4 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Ndc1_Nup PF09531.10 GAM17185.1 - 5.4 5.6 13.8 0.95 8.1 9.3 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 GAM17186.1 - 2.5e-32 110.4 29.9 5e-06 27.1 0.6 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat zf-RING_UBOX PF13445.6 GAM17186.1 - 2.7e-08 33.7 3.6 2.7e-08 33.7 3.6 2.8 2 0 0 2 2 1 1 RING-type zinc-finger PQQ_3 PF13570.6 GAM17186.1 - 2.5e-07 31.0 3.7 0.42 11.2 0.0 5.9 6 1 0 6 6 6 1 PQQ-like domain zf-C3HC4_2 PF13923.6 GAM17186.1 - 5.5e-06 26.1 2.1 5.5e-06 26.1 2.1 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 GAM17186.1 - 1e-05 25.2 1.0 4.1e-05 23.3 1.0 2.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 GAM17186.1 - 1.4e-05 25.1 1.5 1.4e-05 25.1 1.5 2.6 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GAM17186.1 - 2e-05 24.4 2.4 2e-05 24.4 2.4 3.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) WD40_like PF17005.5 GAM17186.1 - 5e-05 22.8 1.9 0.41 9.9 0.0 3.1 1 1 2 3 3 3 2 WD40-like domain zf-RING_5 PF14634.6 GAM17186.1 - 0.00011 22.0 2.3 0.00011 22.0 2.3 2.8 2 0 0 2 2 2 1 zinc-RING finger domain Rootletin PF15035.6 GAM17186.1 - 0.0003 20.9 5.7 0.00045 20.3 5.7 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Nup160 PF11715.8 GAM17186.1 - 0.00033 19.4 7.4 0.035 12.7 0.1 4.0 3 1 2 5 5 5 2 Nucleoporin Nup120/160 U-box PF04564.15 GAM17186.1 - 0.00065 19.8 0.0 0.0024 18.0 0.0 2.0 2 0 0 2 2 1 1 U-box domain Sina PF03145.16 GAM17186.1 - 0.00071 19.6 10.4 0.065 13.2 2.8 2.4 1 1 1 2 2 2 2 Seven in absentia protein family zf-TRAF PF02176.18 GAM17186.1 - 0.00086 19.9 11.1 0.0035 18.0 11.1 2.2 1 0 0 1 1 1 1 TRAF-type zinc finger Prok-RING_4 PF14447.6 GAM17186.1 - 0.0014 18.5 2.0 0.0014 18.5 2.0 2.8 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAM17186.1 - 0.0015 18.4 1.2 0.0015 18.4 1.2 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) CEP63 PF17045.5 GAM17186.1 - 0.0016 18.4 5.4 0.0024 17.9 5.4 1.1 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa zf-RING_2 PF13639.6 GAM17186.1 - 0.0031 17.8 2.3 0.0031 17.8 2.3 3.8 3 1 0 3 3 1 1 Ring finger domain zf-TRAF_2 PF15965.5 GAM17186.1 - 0.013 16.0 5.7 0.013 16.0 5.7 2.6 2 0 0 2 2 2 0 TRAF-like zinc-finger CCDC144C PF14915.6 GAM17186.1 - 0.013 14.6 5.5 0.02 14.0 5.5 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Taxilin PF09728.9 GAM17186.1 - 0.025 13.8 7.2 0.034 13.3 7.2 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein ADIP PF11559.8 GAM17186.1 - 0.035 14.2 4.3 0.059 13.5 4.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.8 GAM17186.1 - 0.059 13.6 4.5 0.1 12.8 4.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 GAM17186.1 - 0.089 12.9 5.3 0.15 12.2 5.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAP1_N PF04849.13 GAM17186.1 - 0.11 11.7 7.5 0.17 11.0 7.5 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region zf-RING_10 PF16685.5 GAM17186.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.4 2 1 0 2 2 1 0 zinc RING finger of MSL2 Fez1 PF06818.15 GAM17186.1 - 0.19 12.2 4.2 0.29 11.6 4.2 1.2 1 0 0 1 1 1 0 Fez1 EzrA PF06160.12 GAM17186.1 - 0.26 9.4 7.0 0.35 9.0 7.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 GAM17186.1 - 0.34 10.4 1.4 0.49 9.9 1.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 GAM17186.1 - 0.93 9.3 5.9 0.45 10.3 2.2 2.1 1 1 1 2 2 2 0 Septum formation initiator zf-U11-48K PF05253.12 GAM17186.1 - 1.1 9.3 6.7 19 5.3 0.1 4.0 4 0 0 4 4 4 0 U11-48K-like CHHC zinc finger HMMR_N PF15905.5 GAM17186.1 - 1.6 8.1 8.9 2.9 7.3 8.7 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 GAM17186.1 - 5.3 7.5 5.8 32 5.0 0.5 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FapA PF03961.13 GAM17186.1 - 6.9 5.2 7.2 8.8 4.8 6.5 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Homeobox_KN PF05920.11 GAM17188.1 - 2.9e-09 36.7 0.0 6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAM17188.1 - 7.2e-08 32.2 0.1 1.8e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 Homeodomain IMUP PF15761.5 GAM17188.1 - 5.7 7.7 7.7 20 5.9 0.8 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein TraT PF05818.12 GAM17189.1 - 1.2 8.7 3.3 1.6 8.4 3.3 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Ribosomal_L7Ae PF01248.26 GAM17190.1 - 7e-05 22.5 0.0 0.00036 20.2 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AAA PF00004.29 GAM17191.1 - 2e-32 112.4 0.0 1.4e-31 109.6 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAM17191.1 - 4.6e-07 30.5 0.0 9.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM17191.1 - 1.1e-05 25.7 0.1 0.00013 22.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM17191.1 - 1.2e-05 25.8 0.0 2.9e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 GAM17191.1 - 5.8e-05 22.8 0.8 0.14 11.7 0.0 2.7 2 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 GAM17191.1 - 5.9e-05 23.4 0.0 0.00025 21.4 0.0 2.1 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.6 GAM17191.1 - 0.00011 22.2 0.0 0.00028 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAM17191.1 - 0.00023 21.6 0.0 0.00052 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 GAM17191.1 - 0.00024 20.4 0.1 0.00038 19.8 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 GAM17191.1 - 0.00059 19.6 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 GAM17191.1 - 0.00078 19.3 0.0 0.0023 17.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAM17191.1 - 0.0011 18.6 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 GAM17191.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAM17191.1 - 0.0012 18.7 0.0 0.0031 17.3 0.0 1.7 1 1 0 2 2 1 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 GAM17191.1 - 0.0013 18.6 0.2 1.2 9.0 0.0 2.3 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea RuvB_N PF05496.12 GAM17191.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 GAM17191.1 - 0.0018 18.0 0.0 0.0048 16.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 GAM17191.1 - 0.0021 18.1 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GAM17191.1 - 0.0023 18.2 0.0 0.005 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GAM17191.1 - 0.0024 18.0 0.0 0.0088 16.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 GAM17191.1 - 0.0025 17.6 0.0 0.0059 16.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Cytidylate_kin PF02224.18 GAM17191.1 - 0.0026 17.5 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase AAA_5 PF07728.14 GAM17191.1 - 0.0026 17.8 0.1 0.0056 16.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 GAM17191.1 - 0.0042 17.6 0.0 0.007 16.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.15 GAM17191.1 - 0.0057 16.6 0.2 0.027 14.4 0.1 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 GAM17191.1 - 0.0059 17.0 0.3 0.076 13.3 0.1 2.3 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAM17191.1 - 0.0067 15.6 0.1 0.02 14.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.16 GAM17191.1 - 0.012 15.1 0.0 0.046 13.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein CPT PF07931.12 GAM17191.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RsgA_GTPase PF03193.16 GAM17191.1 - 0.017 15.0 0.1 0.055 13.4 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 GAM17191.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GAM17191.1 - 0.019 14.9 0.0 0.05 13.5 0.0 1.7 1 1 0 1 1 1 0 NACHT domain DnaB_C PF03796.15 GAM17191.1 - 0.024 14.0 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PduV-EutP PF10662.9 GAM17191.1 - 0.026 14.3 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 GAM17191.1 - 0.035 13.3 0.6 1 8.5 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain NMO PF03060.15 GAM17191.1 - 0.041 13.3 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Mg_chelatase PF01078.21 GAM17191.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 GAM17191.1 - 0.049 12.9 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 GAM17191.1 - 0.064 13.4 0.1 0.24 11.5 0.0 2.0 2 1 0 2 2 1 0 Sigma-54 interaction domain SRPRB PF09439.10 GAM17191.1 - 0.069 12.6 0.1 0.56 9.6 0.0 2.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.26 GAM17191.1 - 0.076 12.7 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 GAM17191.1 - 0.078 12.3 0.1 0.29 10.4 0.1 1.9 1 1 0 1 1 1 0 KaiC AAA_6 PF12774.7 GAM17191.1 - 0.088 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region ResIII PF04851.15 GAM17191.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 GAM17191.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 GAM17191.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein eIF-3c_N PF05470.12 GAM17192.1 - 2.7e-119 399.2 33.5 3.7e-65 220.4 19.3 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 GAM17192.1 - 1.7e-10 41.3 0.5 4.3e-09 36.8 0.0 3.0 3 0 0 3 3 3 1 PCI domain LepB_GAP_N PF18172.1 GAM17192.1 - 0.0025 17.7 0.6 4.2 7.2 0.0 3.8 3 0 0 3 3 3 2 LepB GAP domain N-terminal subdomain Adaptin_binding PF10199.9 GAM17192.1 - 0.93 10.1 8.9 23 5.6 8.9 3.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 ERCC4 PF02732.15 GAM17193.1 - 2.3e-17 63.6 2.8 4.1e-17 62.8 0.0 2.3 2 0 0 2 2 2 1 ERCC4 domain SWIM PF04434.17 GAM17193.1 - 0.0013 18.3 0.1 0.0025 17.4 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger SAM_2 PF07647.17 GAM17193.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Macoilin PF09726.9 GAM17193.1 - 0.54 8.8 12.7 0.72 8.3 12.7 1.2 1 0 0 1 1 1 0 Macoilin family Oxysterol_BP PF01237.18 GAM17194.1 - 7.9e-84 281.6 4.1 2.5e-81 273.4 4.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Git3 PF11710.8 GAM17195.1 - 0.03 14.1 0.7 0.045 13.5 0.7 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 VWA_N PF08399.11 GAM17196.1 - 3.1 8.3 17.1 2.6 8.5 6.3 3.1 3 0 0 3 3 3 0 VWA N-terminal Zip PF02535.22 GAM17196.1 - 5 6.2 4.6 7.1 5.7 4.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DnaJ PF00226.31 GAM17197.1 - 1.3e-13 50.9 0.6 3.7e-13 49.4 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 GAM17197.1 - 5.5e-13 48.5 0.0 2e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 GYF domain 2 KTSC PF13619.6 GAM17197.1 - 0.041 13.7 1.1 12 5.8 0.0 3.5 3 0 0 3 3 3 0 KTSC domain Com_YlbF PF06133.11 GAM17197.1 - 0.06 13.9 1.6 5.8 7.6 0.4 2.6 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA FNIP PF05725.12 GAM17198.1 - 2.3e-77 254.9 30.8 6e-13 48.7 0.3 9.5 3 2 7 12 12 12 11 FNIP Repeat CoaE PF01121.20 GAM17199.1 - 2.9e-46 157.4 0.2 3.6e-46 157.1 0.2 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 GAM17199.1 - 1.9e-05 25.2 1.5 0.0001 22.8 1.5 2.1 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 GAM17199.1 - 0.014 15.5 0.4 0.18 12.0 0.4 2.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAM17199.1 - 0.027 14.7 1.7 0.14 12.4 1.7 2.2 1 1 0 1 1 1 0 AAA domain ATP_bind_2 PF03668.15 GAM17199.1 - 0.07 12.4 1.0 1.9 7.7 0.2 2.0 2 0 0 2 2 2 0 P-loop ATPase protein family AAA_24 PF13479.6 GAM17199.1 - 0.11 12.2 1.2 0.25 11.0 1.2 1.6 1 1 0 1 1 1 0 AAA domain zf-CRD PF17979.1 GAM17200.1 - 2.5e-32 112.2 6.6 2.5e-32 112.2 6.6 2.7 1 1 1 2 2 1 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 GAM17200.1 - 3.3e-18 65.8 2.1 1.4e-17 63.8 0.6 2.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 GAM17200.1 - 7e-11 42.3 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 GAM17200.1 - 1.7e-07 31.4 12.9 1.7e-07 31.4 12.9 4.1 5 1 1 6 6 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM17200.1 - 1e-06 28.5 13.5 1e-06 28.5 13.5 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM17200.1 - 3.1e-06 26.9 13.8 3.1e-06 26.9 13.8 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FHA_2 PF17913.1 GAM17200.1 - 1.8e-05 24.9 0.5 6.6e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 FHA domain zf-CCHH PF10283.9 GAM17200.1 - 6.8e-05 22.8 4.6 0.00016 21.6 4.6 1.7 1 0 0 1 1 1 1 PBZ domain zf-C3HC4 PF00097.25 GAM17200.1 - 0.00011 22.0 12.9 0.00011 22.0 12.9 3.5 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GAM17200.1 - 0.0012 18.6 5.3 0.0012 18.6 5.3 3.1 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 GAM17200.1 - 0.0063 16.5 15.1 0.0063 16.5 15.1 3.9 3 1 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAM17200.1 - 0.027 14.7 9.3 0.027 14.7 9.3 3.6 4 0 0 4 4 4 0 RING-H2 zinc finger domain AAA_23 PF13476.6 GAM17201.1 - 3.9e-05 24.2 31.5 0.00017 22.2 3.1 2.1 2 0 0 2 2 2 2 AAA domain SR-25 PF10500.9 GAM17201.1 - 0.00037 20.2 3.4 0.00037 20.2 3.4 3.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 GAM17201.1 - 0.00058 20.0 65.0 0.059 13.4 15.6 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 GAM17201.1 - 0.003 17.6 12.1 0.003 17.6 12.1 2.7 3 0 0 3 3 3 1 Protein Family FAM60A Med3 PF11593.8 GAM17201.1 - 0.0031 16.8 5.6 0.0031 16.8 5.6 3.8 3 1 0 3 3 2 1 Mediator complex subunit 3 fungal Nop53 PF07767.11 GAM17201.1 - 0.0063 16.0 16.0 0.0063 16.0 16.0 2.2 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) SprA-related PF12118.8 GAM17201.1 - 0.016 14.4 45.9 0.02 14.0 6.3 2.1 2 0 0 2 2 2 0 SprA-related family SOBP PF15279.6 GAM17201.1 - 0.52 10.9 43.6 0.8 10.3 10.3 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Macoilin PF09726.9 GAM17201.1 - 2.5 6.5 34.2 0.3 9.6 9.7 2.2 2 0 0 2 2 2 0 Macoilin family PA26 PF04636.13 GAM17201.1 - 8.1 5.2 19.2 0.83 8.5 9.3 2.3 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) FAM199X PF15814.5 GAM17201.1 - 8.8 5.3 25.1 2.7 6.9 8.1 2.5 2 0 0 2 2 2 0 Protein family FAM199X Ribosomal_L18 PF17135.4 GAM17202.1 - 2.7e-73 245.4 3.4 3.2e-73 245.1 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 GAM17202.1 - 0.019 15.6 0.5 0.032 14.9 0.5 1.4 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Abhydrolase_1 PF00561.20 GAM17203.1 - 1.8e-12 47.4 0.1 8.1e-09 35.5 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM17203.1 - 1.6e-11 45.3 0.0 1.8e-11 45.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM17203.1 - 6.5e-07 28.8 0.0 9.5e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 GAM17203.1 - 0.0063 16.0 0.0 0.62 9.5 0.0 2.1 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Thioesterase PF00975.20 GAM17203.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF3789 PF12664.7 GAM17203.1 - 0.23 11.2 2.5 0.4 10.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) HA2 PF04408.23 GAM17204.1 - 7.6e-24 84.1 0.0 7.6e-24 84.1 0.0 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAM17204.1 - 5.6e-18 65.1 0.0 1.7e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAM17204.1 - 1.4e-11 44.8 0.0 3.7e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM17204.1 - 1.2e-07 31.7 0.1 3.1e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAM17204.1 - 5.3e-07 30.0 0.0 1.4e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM17204.1 - 0.00012 22.4 0.0 0.00031 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 GAM17204.1 - 0.00019 20.8 0.0 0.00038 19.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 GAM17204.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 GAM17204.1 - 0.0032 17.1 0.1 0.0095 15.6 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.29 GAM17204.1 - 0.015 15.7 0.2 0.33 11.4 0.2 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 GAM17204.1 - 0.025 14.6 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 GAM17204.1 - 0.038 14.5 3.0 0.12 12.9 0.2 2.9 2 1 0 2 2 1 0 ABC transporter AAA_24 PF13479.6 GAM17204.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAM17204.1 - 0.097 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 GAM17204.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 GAM17204.1 - 0.12 12.3 5.1 1.1 9.2 0.0 3.0 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit ATPase PF06745.13 GAM17204.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 KaiC 2C_adapt PF08793.10 GAM17204.1 - 0.21 11.8 2.4 2.3 8.5 0.6 3.0 3 0 0 3 3 3 0 2-cysteine adaptor domain Menin PF05053.13 GAM17204.1 - 0.4 9.0 6.9 0.57 8.5 6.9 1.1 1 0 0 1 1 1 0 Menin Pkinase PF00069.25 GAM17206.1 - 6.6e-60 202.7 0.1 8.9e-60 202.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17206.1 - 2.8e-18 66.2 0.0 5.2e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM17206.1 - 2e-07 31.2 0.0 0.00016 21.6 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 GAM17206.1 - 0.00034 20.0 0.0 0.00058 19.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM17206.1 - 0.065 12.6 0.3 0.12 11.8 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_4 PF13637.6 GAM17207.1 - 5.5e-29 100.2 9.5 5e-06 27.0 0.1 7.2 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM17207.1 - 1.9e-22 79.0 18.7 0.00012 22.3 0.6 10.4 2 1 9 11 11 11 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM17207.1 - 6.5e-22 77.9 14.5 1.2e-06 29.0 0.4 5.1 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM17207.1 - 2.7e-12 45.7 8.9 2.9 8.8 0.1 10.0 8 3 3 11 11 11 2 Ankyrin repeat Ank PF00023.30 GAM17207.1 - 0.00082 19.7 5.5 15 6.2 0.0 7.1 3 3 3 6 6 6 1 Ankyrin repeat ENTH PF01417.20 GAM17207.1 - 0.00087 19.3 0.8 14 5.7 0.0 4.9 4 1 3 7 7 7 2 ENTH domain Tom37 PF10568.9 GAM17207.1 - 0.042 14.2 0.5 7.2 6.9 0.0 4.0 3 1 2 5 5 5 0 Outer mitochondrial membrane transport complex protein DUF1707 PF08044.11 GAM17207.1 - 0.05 13.7 4.5 8.5 6.5 0.0 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF1707) LBP_BPI_CETP PF01273.25 GAM17208.1 - 0.00072 19.2 0.1 0.0014 18.2 0.1 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain PSII_Pbs31 PF18240.1 GAM17208.1 - 1.1 9.8 3.6 3.2 8.3 0.4 2.9 2 1 1 3 3 3 0 Photosystem II Psb31 protein NTP_transf_4 PF13562.6 GAM17208.1 - 1.3 9.3 6.9 0.66 10.2 0.5 3.2 3 1 1 4 4 4 0 Sugar nucleotidyl transferase Toprim_Crpt PF13342.6 GAM17208.1 - 1.5 8.9 11.2 0.65 10.0 0.9 4.2 3 1 1 4 4 4 0 C-terminal repeat of topoisomerase PAH PF02671.21 GAM17208.1 - 2.6 8.3 5.9 6.5 7.0 1.4 3.4 2 1 0 2 2 2 0 Paired amphipathic helix repeat His_Phos_1 PF00300.22 GAM17209.1 - 1.9e-27 96.2 0.0 2.2e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MgrB PF13998.6 GAM17209.1 - 0.21 11.5 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 MgrB protein Homeobox_KN PF05920.11 GAM17210.1 - 3.6e-17 62.0 0.1 7.2e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAM17210.1 - 7.9e-08 32.0 0.3 1.8e-07 30.9 0.3 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 GAM17210.1 - 0.0044 16.5 0.0 0.28 10.7 0.0 2.6 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez DUF3439 PF11921.8 GAM17210.1 - 0.13 12.2 3.5 0.13 12.2 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Proteasome PF00227.26 GAM17211.1 - 1e-35 123.0 0.3 1.2e-35 122.7 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Cytomega_UL20A PF05984.12 GAM17211.1 - 0.13 12.5 0.2 0.86 9.9 0.1 2.1 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Ank_2 PF12796.7 GAM17212.1 - 0.00025 21.6 2.8 0.0019 18.7 0.1 3.7 5 1 0 5 5 5 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAM17212.1 - 0.045 14.2 1.2 1.8 9.1 0.1 4.0 3 2 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 GAM17212.1 - 0.075 13.6 1.3 23 6.0 0.0 4.9 5 0 0 5 5 5 0 Ankyrin repeat MAP65_ASE1 PF03999.12 GAM17212.1 - 7.7 5.1 9.9 0.28 9.8 0.2 2.1 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Tim44 PF04280.15 GAM17213.1 - 4.4e-12 46.3 0.0 1.3e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Tim44-like domain ubiquitin PF00240.23 GAM17214.1 - 2e-13 49.9 0.0 4.9e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM17214.1 - 1.6e-05 24.7 0.1 4.3e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3439 PF11921.8 GAM17214.1 - 0.11 12.4 13.8 0.23 11.4 13.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ubiquitin_2 PF14560.6 GAM17214.1 - 0.12 12.9 0.4 0.43 11.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Mucin PF01456.17 GAM17214.1 - 0.22 11.5 23.7 0.97 9.4 23.7 2.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 GAM17214.1 - 0.37 8.7 9.0 0.74 7.7 9.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ribonuc_P_40 PF08584.11 GAM17214.1 - 2.6 7.2 7.8 0.46 9.7 2.7 2.1 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit FSA_C PF10479.9 GAM17214.1 - 5.5 5.0 9.6 8.5 4.4 9.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus UTP15_C PF09384.10 GAM17215.1 - 2.5e-26 92.1 2.6 4.1e-26 91.4 2.6 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 GAM17215.1 - 4.4e-18 65.3 5.2 2.3e-05 25.0 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 GAM17215.1 - 7.4e-10 38.6 0.1 0.00099 18.5 0.2 2.6 1 1 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 GAM17215.1 - 1.9e-06 28.0 0.0 0.24 11.7 0.0 4.4 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM17215.1 - 0.013 14.2 2.2 1.4 7.5 0.3 2.6 2 1 0 3 3 3 0 Nucleoporin Nup120/160 RNA_polI_A34 PF08208.11 GAM17215.1 - 0.077 13.1 21.0 0.16 12.1 21.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 GAM17215.1 - 0.43 10.4 19.5 0.021 14.6 13.6 1.8 2 0 0 2 2 2 0 Coilin N-terminus Ank_4 PF13637.6 GAM17217.1 - 8.8e-05 23.0 0.2 0.11 13.2 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM17217.1 - 0.00021 21.8 0.1 0.00076 20.0 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 GAM17217.1 - 0.0019 18.1 3.0 0.01 15.7 1.8 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) Ank_3 PF13606.6 GAM17217.1 - 0.0073 16.7 0.0 16 6.4 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 GAM17217.1 - 0.018 15.4 0.0 4.2 7.8 0.0 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF2373 PF10180.9 GAM17217.1 - 0.16 11.8 0.9 0.28 11.0 0.9 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Ank_2 PF12796.7 GAM17218.1 - 3.4e-08 34.0 0.1 0.00025 21.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM17218.1 - 4.4e-06 26.6 0.9 0.38 11.5 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAM17218.1 - 0.00024 21.3 0.0 2 8.8 0.0 3.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM17218.1 - 0.0038 17.8 0.3 1.2 9.8 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Inj_translocase PF16928.5 GAM17218.1 - 0.051 13.0 3.2 0.1 12.0 3.2 1.4 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Macoilin PF09726.9 GAM17218.1 - 0.64 8.5 18.3 1 7.9 18.3 1.2 1 0 0 1 1 1 0 Macoilin family Phage_CRI PF05144.14 GAM17219.1 - 0.0097 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Phage replication protein CRI Beach PF02138.18 GAM17220.1 - 1.5e-122 408.3 0.0 3.8e-122 407.0 0.0 1.8 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 GAM17220.1 - 1.1e-58 198.8 4.4 1.1e-58 198.8 4.4 5.0 5 1 1 6 6 6 2 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 GAM17220.1 - 2.6e-27 94.8 0.0 7.4e-27 93.4 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 GAM17220.1 - 1.5e-13 51.1 0.1 1.5e-13 51.1 0.1 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 GAM17220.1 - 2.1e-13 50.5 9.8 0.00046 20.9 0.1 6.3 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF4800 PF16057.5 GAM17220.1 - 8.6e-10 38.3 7.9 1.9e-09 37.2 4.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) ANAPC4_WD40 PF12894.7 GAM17220.1 - 0.00093 19.4 0.7 5.7 7.3 0.1 3.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain ParcG PF10274.9 GAM17220.1 - 0.0063 16.7 0.3 0.036 14.2 0.0 2.5 2 0 0 2 2 2 1 Parkin co-regulated protein UME PF08064.13 GAM17220.1 - 0.07 13.0 0.1 8.4 6.4 0.1 3.7 2 0 0 2 2 2 0 UME (NUC010) domain PqqD PF05402.12 GAM17220.1 - 0.17 12.2 0.2 12 6.3 0.0 2.7 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Ank_4 PF13637.6 GAM17221.1 - 7.4e-38 128.5 6.2 5.7e-08 33.2 0.1 5.7 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM17221.1 - 4e-32 110.7 13.2 8.6e-13 48.7 0.2 4.7 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 GAM17221.1 - 4.8e-26 90.0 9.8 5.8e-06 26.5 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 GAM17221.1 - 1.2e-22 79.7 11.3 1.7e-07 31.4 0.6 6.4 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM17221.1 - 1.2e-22 77.5 12.5 0.00023 21.3 0.3 8.5 7 1 0 7 7 7 4 Ankyrin repeat SH2 PF00017.24 GAM17221.1 - 4.4e-08 33.1 0.0 1.5e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 SH2 domain F-box-like PF12937.7 GAM17221.1 - 1.6e-05 24.7 1.1 3.8e-05 23.5 1.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM17221.1 - 4.5e-05 23.2 0.6 0.00012 21.9 0.6 1.8 1 0 0 1 1 1 1 F-box domain SH2_2 PF14633.6 GAM17221.1 - 0.011 15.2 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 0 SH2 domain CD45 PF12567.8 GAM17221.1 - 1.8 8.6 4.3 0.93 9.5 0.1 2.2 2 0 0 2 2 2 0 Leukocyte receptor CD45 Zip PF02535.22 GAM17221.1 - 2.1 7.5 6.8 2.3 7.3 5.6 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter Folliculin PF11704.8 GAM17222.1 - 0.00014 21.8 0.3 0.00014 21.8 0.3 2.2 3 0 0 3 3 3 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3439 PF11921.8 GAM17222.1 - 0.41 10.6 4.0 1.2 9.1 4.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Kelch_4 PF13418.6 GAM17223.1 - 4.4e-32 109.8 13.2 1.7e-07 31.1 0.3 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM17223.1 - 4.6e-29 99.7 21.0 2.8e-06 27.4 0.1 7.2 6 1 2 8 8 8 6 Kelch motif Kelch_1 PF01344.25 GAM17223.1 - 2.9e-28 97.2 12.4 1.5e-08 34.1 1.3 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 GAM17223.1 - 1.2e-25 89.0 12.2 6.3e-05 22.9 0.1 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 GAM17223.1 - 1.6e-21 75.4 10.3 5.8e-05 22.9 0.0 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 GAM17223.1 - 5.6e-20 71.1 29.3 8.8e-05 22.7 0.0 9.0 9 1 0 9 9 9 5 Galactose oxidase, central domain F-box PF00646.33 GAM17223.1 - 1.3e-07 31.3 0.2 2.8e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM17223.1 - 2.6e-07 30.4 0.2 5.7e-07 29.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like VWA_2 PF13519.6 GAM17224.1 - 1.2e-24 87.0 2.2 1.2e-23 83.8 0.0 3.2 3 1 1 4 4 4 1 von Willebrand factor type A domain UIM PF02809.20 GAM17224.1 - 2.4e-06 27.1 7.7 0.0019 18.0 2.2 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif Ssl1 PF04056.14 GAM17224.1 - 4.1e-06 26.8 1.0 1.3e-05 25.2 0.2 1.9 2 0 0 2 2 2 1 Ssl1-like UB2H PF14814.6 GAM17224.1 - 0.00089 19.2 0.1 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain DUF1887 PF09002.11 GAM17224.1 - 0.0022 16.8 0.2 0.0039 15.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) DUF4362 PF14275.6 GAM17224.1 - 0.0069 16.6 0.1 0.0069 16.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4362) THF_DHG_CYH PF00763.23 GAM17224.1 - 0.068 13.4 1.6 0.15 12.3 0.2 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Peptidase_M8 PF01457.16 GAM17225.1 - 6.3e-53 180.3 3.8 9.2e-53 179.7 3.8 1.2 1 0 0 1 1 1 1 Leishmanolysin DUF3824 PF12868.7 GAM17225.1 - 3.6 8.2 9.6 0.58 10.8 5.3 1.7 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF4558 PF15104.6 GAM17226.1 - 0.028 14.5 0.4 0.031 14.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) DinB PF05163.12 GAM17226.1 - 0.1 12.5 0.6 0.12 12.3 0.6 1.0 1 0 0 1 1 1 0 DinB family DUF3959 PF13105.6 GAM17226.1 - 0.16 11.5 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Ca_bind_SSO6904 PF18249.1 GAM17227.1 - 0.092 13.1 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Calcium binding protein SSO6904 Kelch_4 PF13418.6 GAM17228.1 - 1.9e-48 162.3 14.0 2.8e-10 40.0 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM17228.1 - 1.6e-33 114.1 16.7 5.9e-06 26.1 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAM17228.1 - 1e-30 105.4 12.7 3.8e-06 27.0 0.1 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM17228.1 - 7.1e-26 89.5 17.6 7.4e-10 38.3 0.2 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 GAM17228.1 - 7.6e-25 86.3 14.3 7.5e-08 32.4 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 GAM17228.1 - 9.1e-19 66.6 17.3 0.00049 20.0 0.2 5.9 6 0 0 6 6 6 5 Kelch motif zf-C3HC4_3 PF13920.6 GAM17228.1 - 4.2e-07 29.7 7.6 7.6e-07 28.9 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.17 GAM17228.1 - 3.4e-05 23.9 7.4 3.4e-05 23.9 7.4 4.0 2 1 1 3 3 2 1 K-box region RAG2 PF03089.14 GAM17228.1 - 0.00086 18.4 0.1 1.3 8.0 0.0 2.5 2 0 0 2 2 2 2 Recombination activating protein 2 LptF_LptG PF03739.14 GAM17228.1 - 0.016 14.0 0.0 0.047 12.5 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Prok-RING_4 PF14447.6 GAM17228.1 - 0.2 11.6 8.1 0.35 10.8 8.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RecA PF00154.21 GAM17229.1 - 9e-35 120.4 0.1 1.6e-33 116.3 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein Rad51 PF08423.11 GAM17229.1 - 1.6e-13 50.5 0.1 1.6e-12 47.2 0.0 2.3 2 1 0 2 2 2 1 Rad51 ATPase PF06745.13 GAM17229.1 - 1e-06 28.3 0.0 4e-06 26.3 0.0 1.9 1 1 1 2 2 2 1 KaiC AAA_25 PF13481.6 GAM17229.1 - 0.00025 20.7 0.0 0.00079 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAM17229.1 - 0.00025 20.8 0.0 0.00067 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 GAM17229.1 - 0.0033 16.8 0.2 1.1 8.6 0.0 3.0 2 1 0 3 3 3 1 DnaB-like helicase C terminal domain CobU PF02283.16 GAM17229.1 - 0.049 13.2 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF29 PF01724.16 GAM17229.1 - 0.051 13.8 0.0 0.1 12.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF29 AAA_22 PF13401.6 GAM17229.1 - 0.061 13.6 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF4611 PF15387.6 GAM17229.1 - 0.1 12.8 1.5 0.19 12.0 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 GAM17229.1 - 0.18 11.4 1.1 0.32 10.6 1.1 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 GAM17229.1 - 4 6.7 5.3 6.5 6.0 5.3 1.2 1 0 0 1 1 1 0 NOA36 protein Smg8_Smg9 PF10220.9 GAM17231.1 - 9.5e-06 24.2 0.2 9.5e-06 24.2 0.2 2.1 2 0 0 2 2 2 1 Smg8_Smg9 Dynamin_N PF00350.23 GAM17231.1 - 0.0042 17.2 0.3 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAM17231.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Menin PF05053.13 GAM17231.1 - 1.2 7.4 7.1 2 6.7 7.1 1.2 1 0 0 1 1 1 0 Menin Pkinase PF00069.25 GAM17232.1 - 3e-51 174.3 0.2 3e-51 174.3 0.2 2.5 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17232.1 - 3.4e-21 75.7 0.0 3.4e-21 75.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GAM17232.1 - 0.016 15.2 1.2 0.067 13.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAM17232.1 - 0.018 14.7 0.3 0.018 14.7 0.3 2.6 2 1 1 3 3 3 0 RIO1 family Ank_2 PF12796.7 GAM17233.1 - 1.1e-06 29.2 6.6 0.35 11.5 0.0 5.7 2 2 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM17233.1 - 3.4e-05 23.9 6.8 1.4 9.7 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 GAM17233.1 - 0.00082 19.6 0.6 42 4.6 0.0 5.6 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM17233.1 - 0.0012 19.4 4.2 14 6.4 0.0 6.0 5 1 2 7 7 7 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM17234.1 - 0.064 13.9 0.5 15 6.3 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 GAM17235.1 - 0.00074 19.3 2.3 0.0013 18.5 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM17235.1 - 0.0023 17.7 1.9 0.0023 17.7 1.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM17235.1 - 0.012 15.6 0.4 0.031 14.3 0.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 GAM17235.1 - 0.023 14.6 1.9 0.047 13.5 1.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GAM17235.1 - 0.029 14.3 3.3 0.077 12.9 3.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM17235.1 - 0.29 11.1 3.1 0.66 10.0 3.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 GAM17235.1 - 0.61 10.5 2.1 1.6 9.1 2.1 1.7 1 0 0 1 1 1 0 Ring finger domain SUI1 PF01253.22 GAM17236.1 - 1.9e-24 86.0 1.1 3.2e-24 85.3 1.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 GAM17236.1 - 0.0037 17.5 0.2 0.0064 16.8 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) RhoGAP PF00620.27 GAM17237.1 - 5.5e-34 117.2 0.4 1.5e-33 115.8 0.4 1.7 1 0 0 1 1 1 1 RhoGAP domain Choline_transpo PF04515.12 GAM17238.1 - 7.6e-39 133.8 13.9 1.4e-38 133.0 13.9 1.4 1 1 0 1 1 1 1 Plasma-membrane choline transporter CitMHS PF03600.16 GAM17238.1 - 0.0011 18.3 4.6 0.0021 17.3 4.6 1.4 1 1 0 1 1 1 1 Citrate transporter DUF2417 PF10329.9 GAM17238.1 - 0.023 14.1 0.3 0.074 12.5 0.3 1.9 1 0 0 1 1 1 0 Region of unknown function (DUF2417) FUSC_2 PF13515.6 GAM17238.1 - 0.51 10.5 17.2 0.85 9.7 3.3 3.4 3 0 0 3 3 3 0 Fusaric acid resistance protein-like Aa_trans PF01490.18 GAM17239.1 - 3.5e-50 170.9 20.2 4.1e-50 170.7 20.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAM17239.1 - 2.1e-06 27.1 2.7 2.1e-06 27.1 2.7 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family EF-hand_1 PF00036.32 GAM17240.1 - 1.1e-10 40.3 0.0 0.002 17.5 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 GAM17240.1 - 1.2e-10 41.7 0.0 2.5e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM17240.1 - 6.4e-09 35.0 0.0 0.19 11.8 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 GAM17240.1 - 4.4e-08 32.3 0.0 0.085 12.4 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GAM17240.1 - 1.8e-05 24.5 0.0 0.001 18.9 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain pair Ribosomal_L12 PF00542.19 GAM17241.1 - 1.1e-16 60.9 5.3 1.1e-16 60.9 5.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 GAM17241.1 - 1.6e-06 27.7 18.9 9.2e-06 25.3 9.3 3.6 3 1 0 3 3 3 2 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 GAM17241.1 - 0.084 12.7 0.4 0.084 12.7 0.4 2.0 2 0 0 2 2 2 0 Stage VI sporulation protein F Aldedh PF00171.22 GAM17242.1 - 7.1e-166 552.3 0.0 8e-166 552.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAM17242.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ras PF00071.22 GAM17243.1 - 4.6e-10 39.3 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Ras family CCG PF02754.16 GAM17243.1 - 0.04 14.1 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 Cysteine-rich domain Roc PF08477.13 GAM17243.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase WAP PF00095.21 GAM17244.1 - 5.2e-10 39.5 55.0 0.00074 19.9 11.7 3.1 3 0 0 3 3 3 3 WAP-type (Whey Acidic Protein) 'four-disulfide core' Conotoxin_I2 PF17557.2 GAM17244.1 - 0.0039 17.3 40.3 0.19 11.8 6.9 3.5 3 0 0 3 3 3 3 I2-superfamily conotoxins Pkinase PF00069.25 GAM17248.1 - 2e-25 89.7 0.2 3.9e-25 88.7 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17248.1 - 4.3e-20 72.1 0.0 8.3e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM17248.1 - 0.0019 17.6 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 GAM17248.1 - 0.0065 17.1 9.5 4.2 8.2 0.0 6.7 9 0 0 9 9 9 1 Sel1 repeat Pkinase_fungal PF17667.1 GAM17248.1 - 0.029 13.2 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FA_hydroxylase PF04116.13 GAM17249.1 - 2.2e-17 63.7 17.3 2.2e-17 63.7 17.3 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RhoGEF PF00621.20 GAM17250.1 - 7.2e-46 156.7 1.7 1e-45 156.2 0.4 1.9 2 0 0 2 2 2 1 RhoGEF domain AAA_23 PF13476.6 GAM17250.1 - 0.012 16.2 0.3 0.044 14.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain Nif11 PF07862.11 GAM17250.1 - 0.15 12.4 0.3 6.4 7.2 0.2 2.8 2 0 0 2 2 2 0 Nif11 domain LMP PF04778.12 GAM17250.1 - 0.34 10.8 6.7 5 7.0 0.3 3.0 2 0 0 2 2 2 0 LMP repeated region DUF3035 PF11233.8 GAM17250.1 - 6.7 7.0 7.7 1.4 9.2 1.9 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3035) DNA_pol_B_2 PF03175.13 GAM17251.1 - 0.00096 18.1 0.4 0.0016 17.4 0.3 1.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral FNIP PF05725.12 GAM17253.1 - 3.3e-65 216.0 20.7 3.7e-12 46.2 0.1 10.4 6 1 1 10 10 10 9 FNIP Repeat NIP_1 PF08995.10 GAM17253.1 - 1.1 9.7 3.3 4.5 7.7 0.1 3.7 4 1 0 4 4 4 0 Necrosis inducing protein-1 Coiled PF05710.12 GAM17254.1 - 0.0099 16.7 18.4 0.048 14.5 18.4 1.8 1 1 0 1 1 1 1 Coiled coil Coiled PF05710.12 GAM17255.1 - 0.018 15.9 17.6 0.073 13.9 17.6 1.7 1 1 0 1 1 1 0 Coiled coil Coiled PF05710.12 GAM17256.1 - 0.0099 16.7 18.4 0.048 14.5 18.4 1.8 1 1 0 1 1 1 1 Coiled coil WD40 PF00400.32 GAM17257.1 - 1.3e-30 105.0 16.0 1.5e-06 28.8 0.5 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.12 GAM17257.1 - 2.1e-19 69.8 0.1 3.9e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 GAM17257.1 - 1e-07 32.2 2.8 0.00044 20.5 0.5 4.2 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cob_adeno_trans PF01923.18 GAM17258.1 - 5.7e-57 192.4 0.0 9.1e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase SAP PF02037.27 GAM17260.1 - 1.4e-05 24.8 0.1 1.4e-05 24.8 0.1 1.8 2 0 0 2 2 2 1 SAP domain Carboxyl_trans PF01039.22 GAM17261.1 - 6.6e-155 516.5 0.1 7.8e-155 516.3 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 GAM17261.1 - 0.31 10.3 1.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase PBP1_TM PF14812.6 GAM17262.1 - 9.9 6.6 8.5 1 9.7 1.3 2.8 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RCC1 PF00415.18 GAM17263.1 - 1.5e-58 195.2 30.0 2.2e-11 44.2 0.2 8.8 7 3 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM17263.1 - 3.2e-39 131.9 45.3 2.4e-10 40.0 0.6 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Macin PF14865.6 GAM17263.1 - 0.03 14.8 2.3 5.7 7.5 0.0 3.6 4 0 0 4 4 4 0 Macin NAGLU PF05089.12 GAM17264.1 - 8.9e-136 452.2 6.8 8.9e-136 452.2 6.8 1.6 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 GAM17264.1 - 3.7e-67 226.7 1.9 5.7e-67 226.0 1.9 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 GAM17264.1 - 4.8e-19 67.9 0.0 1.1e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Oxidored_molyb PF00174.19 GAM17265.1 - 5.5e-59 198.6 0.0 1.4e-58 197.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAM17265.1 - 1.9e-35 121.9 0.1 4.1e-35 120.8 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cas6 PF09559.10 GAM17265.1 - 0.017 15.1 0.0 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Cas6 Crispr BNR PF02012.20 GAM17265.1 - 0.1 12.7 2.0 0.33 11.1 0.2 2.9 3 0 0 3 3 3 0 BNR/Asp-box repeat CLU PF13236.6 GAM17266.1 - 3e-61 207.1 0.0 1.8e-60 204.5 0.0 2.3 2 0 0 2 2 2 1 Clustered mitochondria SH2 PF00017.24 GAM17266.1 - 1.3e-09 38.1 0.0 4.2e-09 36.4 0.0 2.0 1 0 0 1 1 1 1 SH2 domain eIF3_p135 PF12807.7 GAM17266.1 - 1.8e-08 34.7 8.5 1.8e-06 28.1 8.5 3.1 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_11 PF13414.6 GAM17266.1 - 0.0065 16.1 0.0 1 9.1 0.2 2.6 2 0 0 2 2 2 1 TPR repeat MIT PF04212.18 GAM17266.1 - 0.019 15.0 0.3 2.4 8.3 0.2 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 GAM17266.1 - 0.12 12.9 0.7 64 4.2 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RGS PF00615.19 GAM17267.1 - 3.4e-24 85.4 1.0 9e-24 84.0 1.0 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain dNK PF01712.19 GAM17268.1 - 1e-41 143.1 0.2 1.4e-40 139.4 0.1 1.9 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_28 PF13521.6 GAM17268.1 - 0.0001 22.6 0.0 0.00013 22.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 GAM17268.1 - 0.00087 19.0 0.0 0.002 17.8 0.0 1.8 1 1 0 1 1 1 1 Thymidylate kinase TsaE PF02367.17 GAM17268.1 - 0.002 18.1 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAM17268.1 - 0.085 13.0 0.0 0.4 10.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.7 GAM17270.1 - 1.9e-05 25.2 0.4 0.031 14.9 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM17270.1 - 0.0043 17.4 0.0 12 6.9 0.0 5.2 5 1 0 5 5 5 1 Ankyrin repeat DUF3447 PF11929.8 GAM17270.1 - 0.025 14.5 5.4 0.065 13.2 0.0 4.2 5 1 0 5 5 5 0 Domain of unknown function (DUF3447) His_Phos_1 PF00300.22 GAM17271.1 - 2.3e-30 105.7 0.5 4.1e-30 104.9 0.5 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Helicase_C_3 PF13625.6 GAM17271.1 - 0.046 13.9 0.1 0.3 11.2 0.0 2.0 1 1 1 2 2 2 0 Helicase conserved C-terminal domain RhoGAP PF00620.27 GAM17273.1 - 1.4e-30 106.2 0.0 2e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain ATG_C PF09333.11 GAM17273.1 - 1.4e-09 38.2 0.1 3.5e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 GAM17273.1 - 0.0044 16.8 1.4 0.0081 16.0 1.4 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SBF PF01758.16 GAM17274.1 - 3.7e-46 157.3 14.1 3.7e-46 157.3 14.1 2.0 1 1 1 2 2 2 1 Sodium Bile acid symporter family LMWPc PF01451.21 GAM17274.1 - 1.8e-18 67.2 0.0 3.7e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SBF_like PF13593.6 GAM17274.1 - 4.7e-06 26.2 20.6 6.9e-06 25.6 20.6 1.3 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) DUF1230 PF06799.11 GAM17274.1 - 5.1 7.2 10.0 0.19 11.9 0.3 3.0 2 2 1 3 3 3 0 Conserved in the green lineage and diatoms 27 MFS_MOT1 PF16983.5 GAM17275.1 - 0.014 15.8 2.1 0.014 15.8 2.1 4.1 4 1 0 4 4 4 0 Molybdate transporter of MFS superfamily PfkB PF00294.24 GAM17276.1 - 2.2e-06 27.2 0.1 5.3e-06 26.0 0.1 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase p450 PF00067.22 GAM17277.1 - 7.2e-75 252.5 0.8 2.2e-61 208.0 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 PARP PF00644.20 GAM17278.1 - 6.4e-17 61.8 0.2 5.1e-15 55.6 0.2 2.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-CCHH PF10283.9 GAM17278.1 - 4.3e-13 49.0 3.8 9.6e-13 47.9 3.8 1.6 1 0 0 1 1 1 1 PBZ domain WWE PF02825.20 GAM17278.1 - 5.9e-13 49.2 6.1 6.8e-07 29.8 0.2 3.6 3 0 0 3 3 3 2 WWE domain BRCT PF00533.26 GAM17278.1 - 1.1e-12 48.1 0.0 3.6e-12 46.5 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAM17278.1 - 3.5e-05 23.7 1.1 0.00011 22.1 1.1 1.9 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 GAM17278.1 - 4.4e-05 23.8 0.0 0.00019 21.7 0.0 2.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 GAM17278.1 - 9.1e-05 22.7 0.1 0.0003 21.0 0.1 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain WD40 PF00400.32 GAM17279.1 - 0.00031 21.5 3.6 0.026 15.4 0.1 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Stealth_CR2 PF11380.8 GAM17280.1 - 6.8e-47 158.1 0.2 6.6e-46 154.9 0.0 2.6 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 GAM17280.1 - 2.2e-20 72.3 0.1 2.2e-20 72.3 0.1 3.8 5 0 0 5 5 5 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 GAM17280.1 - 8e-19 67.3 3.9 1.6e-18 66.3 3.9 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 GAM17280.1 - 1.8e-14 53.9 35.0 1.3e-07 31.9 15.7 2.4 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 GAM17280.1 - 1.5e-09 37.4 0.1 7.4e-09 35.2 0.1 2.2 2 0 0 2 2 2 1 Stealth protein CR1, conserved region 1 FNIP PF05725.12 GAM17281.1 - 4.5e-86 282.8 42.7 1.2e-12 47.8 0.0 12.3 9 4 4 13 13 13 10 FNIP Repeat F-box PF00646.33 GAM17281.1 - 0.0066 16.3 0.2 0.023 14.6 0.2 2.0 1 0 0 1 1 1 1 F-box domain RRM_1 PF00076.22 GAM17282.1 - 1.4e-29 101.7 4.0 1.2e-21 76.3 0.3 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM17282.1 - 1.6e-06 27.9 0.1 0.00086 19.1 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_8 PF11835.8 GAM17282.1 - 0.014 15.6 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain RRM_Rrp7 PF17799.1 GAM17282.1 - 0.021 14.6 0.9 2.8 7.7 0.0 3.3 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 GAM17282.1 - 0.033 13.8 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 GAM17282.1 - 3.5 5.7 29.4 1.4 7.0 10.8 2.5 3 0 0 3 3 3 0 Nop14-like family TFIIF_alpha PF05793.12 GAM17282.1 - 6.3 5.3 33.5 5.9 5.4 10.2 2.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IF4E PF01652.18 GAM17283.1 - 1.7e-46 157.9 0.2 2.3e-46 157.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E eIF3g PF12353.8 GAM17284.1 - 1.8e-22 80.1 2.2 3.8e-22 79.0 2.2 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 GAM17284.1 - 1.9e-19 69.2 0.0 3.9e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM17284.1 - 0.0014 18.3 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM17284.1 - 0.0026 17.7 0.0 0.006 16.6 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif EF-hand_1 PF00036.32 GAM17285.1 - 1.5e-40 133.7 11.8 3e-09 35.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAM17285.1 - 3.6e-36 123.4 2.9 2.6e-18 66.2 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAM17285.1 - 4.8e-32 109.6 11.3 5.8e-15 54.9 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 GAM17285.1 - 8.1e-31 103.3 4.9 3.6e-09 35.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAM17285.1 - 7.2e-26 88.5 8.9 1.3e-06 27.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAM17285.1 - 1.2e-14 54.3 0.1 1.1e-08 35.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAM17285.1 - 8.6e-09 35.3 1.1 0.00025 20.9 0.2 2.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAM17285.1 - 1.8e-08 34.7 0.1 0.0029 17.9 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 GAM17285.1 - 4.4e-05 23.4 0.0 0.059 13.4 0.0 3.0 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 GAM17285.1 - 9.6e-05 23.2 0.0 0.072 14.0 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain DUF1103 PF06513.11 GAM17285.1 - 0.00023 20.9 2.7 0.00027 20.6 2.7 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EFhand_Ca_insen PF08726.10 GAM17285.1 - 0.00084 19.4 0.5 0.0042 17.1 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 GAM17285.1 - 0.0014 18.6 0.8 0.95 9.4 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein Dockerin_1 PF00404.18 GAM17285.1 - 0.0019 18.3 3.2 0.35 11.1 1.2 3.1 1 1 2 3 3 3 1 Dockerin type I domain SapB_1 PF05184.15 GAM17285.1 - 0.0022 18.0 1.1 2.7 8.1 0.0 3.4 3 0 0 3 3 3 1 Saposin-like type B, region 1 RNA_pol_Rpb4 PF03874.16 GAM17285.1 - 0.0029 17.9 2.3 0.91 9.9 0.1 3.0 3 1 0 3 3 2 1 RNA polymerase Rpb4 DUF5580 PF17743.1 GAM17285.1 - 0.0051 15.4 0.0 0.0051 15.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) MotA_activ PF09114.10 GAM17285.1 - 0.022 14.9 0.1 0.33 11.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain DUF4497 PF14924.6 GAM17285.1 - 0.026 15.0 0.0 5.2 7.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) dCache_2 PF08269.11 GAM17285.1 - 0.03 13.5 0.2 1.3 8.2 0.0 2.2 1 1 1 2 2 2 0 Cache domain EF-hand_14 PF17959.1 GAM17285.1 - 0.041 14.2 0.1 13 6.2 0.0 2.5 1 1 0 2 2 2 0 EF-hand domain TerB PF05099.13 GAM17285.1 - 0.042 13.8 0.3 2.1 8.3 0.0 2.4 1 1 1 2 2 2 0 Tellurite resistance protein TerB FGAR-AT_linker PF18072.1 GAM17285.1 - 0.055 14.0 0.2 1.1 9.8 0.0 2.5 2 2 1 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain Poly_export PF02563.16 GAM17285.1 - 0.062 13.5 0.1 1.6 9.0 0.0 2.8 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein SurA_N_2 PF13623.6 GAM17285.1 - 0.08 12.8 1.3 2.4 8.0 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain DUF4576 PF15144.6 GAM17285.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Spore_III_AB PF09548.10 GAM17285.1 - 0.11 12.6 0.6 0.32 11.1 0.6 1.7 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Skp1 PF01466.19 GAM17285.1 - 8.9 6.5 8.4 7.1 6.8 0.2 2.6 3 0 0 3 3 2 0 Skp1 family, dimerisation domain WD40 PF00400.32 GAM17286.1 - 2.3e-38 129.5 31.3 1.4e-07 32.1 0.8 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17286.1 - 1.1e-09 38.5 4.1 0.31 11.4 0.1 6.2 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM17286.1 - 2.3e-08 33.8 0.2 4.9e-06 26.1 0.0 2.9 1 1 1 3 3 3 1 WD40-like domain Nup160 PF11715.8 GAM17286.1 - 1.1e-07 30.9 10.2 0.055 12.1 0.1 5.6 3 1 3 6 6 6 4 Nucleoporin Nup120/160 PQQ_2 PF13360.6 GAM17286.1 - 0.00054 19.6 2.5 0.018 14.7 2.5 3.0 1 1 0 1 1 1 1 PQQ-like domain Hira PF07569.11 GAM17286.1 - 0.42 10.3 5.0 4.7 6.9 0.0 3.7 2 1 1 4 4 4 0 TUP1-like enhancer of split Alpha_L_fucos PF01120.17 GAM17287.1 - 9.5e-120 400.2 8.3 1.2e-119 399.8 8.3 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 GAM17287.1 - 4.3e-18 65.7 0.0 7.9e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain GTP_EFTU PF00009.27 GAM17288.1 - 3.8e-49 166.9 0.0 6.6e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 GAM17288.1 - 5.8e-45 151.9 1.5 1.2e-44 150.9 1.5 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 GAM17288.1 - 5.2e-16 58.5 0.0 1.2e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAM17288.1 - 1.8e-06 28.3 0.7 4.1e-06 27.1 0.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.9 GAM17288.1 - 0.00057 19.6 0.3 0.0056 16.4 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 GAM17288.1 - 0.0063 16.0 0.1 0.12 11.8 0.1 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAM17288.1 - 0.01 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Ras family RF3_C PF16658.5 GAM17288.1 - 0.018 14.8 0.1 0.076 12.8 0.0 2.0 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain ACC_central PF08326.12 GAM17289.1 - 0.031 12.5 0.1 0.036 12.3 0.1 1.0 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region Ras PF00071.22 GAM17290.1 - 5.8e-57 191.8 0.9 6.8e-57 191.6 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM17290.1 - 3.1e-32 111.3 0.7 5.1e-32 110.6 0.7 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM17290.1 - 8.7e-14 51.3 0.4 9.8e-14 51.2 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM17290.1 - 6.5e-06 25.8 0.4 1.5e-05 24.6 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM17290.1 - 8.8e-06 25.8 0.3 1.2e-05 25.3 0.3 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAM17290.1 - 9e-05 22.0 0.1 0.00013 21.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAM17290.1 - 0.00011 22.1 0.1 0.46 10.4 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GAM17290.1 - 0.00037 19.9 0.3 0.00044 19.7 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 GAM17290.1 - 0.0037 16.7 0.0 0.0075 15.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein FeoB_N PF02421.18 GAM17290.1 - 0.0038 16.8 0.1 0.05 13.1 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 GAM17290.1 - 0.0057 15.8 1.6 0.37 9.9 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit PduV-EutP PF10662.9 GAM17290.1 - 0.038 13.8 0.2 0.53 10.0 0.1 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MFS_5 PF05631.14 GAM17291.1 - 4.6e-100 335.0 15.0 7.4e-100 334.3 15.0 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 GAM17291.1 - 8.5e-19 67.7 52.3 1.1e-17 64.1 35.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.31 GAM17293.1 - 2.3e-22 79.3 0.5 4.8e-21 75.1 0.1 2.8 2 1 1 3 3 3 1 BTB/POZ domain F5_F8_type_C PF00754.25 GAM17293.1 - 3.1e-07 30.5 0.3 3.1e-07 30.5 0.3 1.8 2 0 0 2 2 2 1 F5/8 type C domain BACK PF07707.15 GAM17293.1 - 0.00021 21.4 0.4 0.46 10.6 0.0 4.2 4 0 0 4 4 4 1 BTB And C-terminal Kelch DUF3342 PF11822.8 GAM17293.1 - 0.019 15.2 0.1 0.74 10.1 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3342) BTB_2 PF02214.22 GAM17293.1 - 0.022 15.1 0.0 0.07 13.5 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain D123 PF07065.14 GAM17294.1 - 9.8e-96 320.5 7.6 7.3e-94 314.4 7.6 2.0 1 1 0 1 1 1 1 D123 R2K_2 PF18299.1 GAM17294.1 - 0.00099 19.0 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 GAM17294.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 ZapB PF06005.12 GAM17295.1 - 0.005 17.3 12.5 0.005 17.3 12.5 8.2 4 1 4 8 8 8 4 Cell division protein ZapB Leu_zip PF15294.6 GAM17295.1 - 9 5.7 94.1 0.048 13.2 39.6 4.7 1 1 3 4 4 4 0 Leucine zipper Snf7 PF03357.21 GAM17296.1 - 2.2e-41 141.3 14.4 2.6e-41 141.1 14.4 1.0 1 0 0 1 1 1 1 Snf7 RE_Bsp6I PF09504.10 GAM17296.1 - 0.0044 16.6 0.5 0.0094 15.6 0.3 1.6 1 1 0 1 1 1 1 Bsp6I restriction endonuclease FliJ PF02050.16 GAM17296.1 - 0.01 16.1 2.2 0.01 16.1 2.2 2.2 1 1 1 2 2 2 1 Flagellar FliJ protein DUF1319 PF07028.11 GAM17296.1 - 0.01 16.0 1.0 0.01 16.0 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Prefoldin PF02996.17 GAM17296.1 - 0.02 14.8 9.6 0.16 11.9 0.0 3.3 2 1 2 4 4 4 0 Prefoldin subunit Spc7 PF08317.11 GAM17296.1 - 0.025 13.5 10.7 0.032 13.1 10.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.6 GAM17296.1 - 0.049 14.1 1.9 2 8.9 0.0 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Glutaredoxin PF00462.24 GAM17296.1 - 0.074 13.3 0.2 0.22 11.8 0.2 1.8 1 0 0 1 1 1 0 Glutaredoxin RasGAP_C PF03836.15 GAM17296.1 - 0.73 10.0 10.2 0.31 11.2 5.7 2.1 1 1 0 2 2 2 0 RasGAP C-terminus APG6_N PF17675.1 GAM17296.1 - 3.3 8.2 17.3 4.4 7.9 3.4 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 GAM17296.1 - 4.1 5.9 12.9 0.45 9.1 5.0 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A FAM76 PF16046.5 GAM17296.1 - 7.6 5.8 12.0 23 4.2 12.0 1.7 1 1 1 2 2 2 0 FAM76 protein PALP PF00291.25 GAM17297.1 - 2.9e-66 223.9 0.3 3.5e-66 223.6 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TPR_1 PF00515.28 GAM17299.1 - 6e-26 89.2 22.5 0.00011 21.8 0.5 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAM17299.1 - 3.5e-19 67.3 21.3 0.00013 21.9 0.0 8.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAM17299.1 - 5.1e-19 66.8 27.7 0.0072 16.4 0.2 8.2 9 0 0 9 9 7 6 Tetratricopeptide repeat ANAPC8 PF04049.13 GAM17299.1 - 7.2e-18 65.0 3.2 4.5e-16 59.2 0.1 2.7 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 GAM17299.1 - 1.3e-14 53.6 15.8 0.00088 19.9 0.1 8.4 6 2 3 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM17299.1 - 7.6e-09 35.1 11.4 3.4e-07 29.8 1.0 5.1 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.6 GAM17299.1 - 1.3e-08 35.0 18.5 0.00045 20.5 0.7 6.1 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM17299.1 - 2.6e-08 34.4 21.2 4.4e-05 24.0 0.0 7.1 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM17299.1 - 4.7e-08 32.5 17.2 0.00057 19.7 0.9 5.4 6 0 0 6 6 4 3 Tetratricopeptide repeat zf-B_box PF00643.24 GAM17299.1 - 2.3e-07 30.8 7.4 5.5e-07 29.6 7.4 1.7 1 0 0 1 1 1 1 B-box zinc finger TPR_19 PF14559.6 GAM17299.1 - 2.4e-05 24.8 23.3 0.07 13.6 0.1 6.8 7 1 1 8 8 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM17299.1 - 0.00043 20.5 16.1 0.026 14.9 0.0 7.4 7 1 1 8 8 8 1 Tetratricopeptide repeat ChAPs PF09295.10 GAM17299.1 - 0.0021 17.1 0.2 0.24 10.3 0.0 2.9 1 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 GAM17299.1 - 0.0024 17.7 18.7 0.05 13.5 0.6 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM17299.1 - 0.0098 16.1 28.6 0.19 12.0 3.5 6.1 5 2 3 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 GAM17299.1 - 0.023 14.7 2.5 0.023 14.7 2.5 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM17299.1 - 0.026 14.6 4.9 1.5 8.9 0.0 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.6 GAM17299.1 - 0.089 12.2 5.6 0.064 12.7 0.4 2.9 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP SepQ PF06622.11 GAM17299.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 SepQ protein TPR_9 PF13371.6 GAM17299.1 - 0.21 11.8 5.4 0.21 11.8 0.0 3.6 3 1 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM17299.1 - 9.9 7.1 25.3 19 6.2 1.2 9.0 10 1 0 10 10 9 0 Tetratricopeptide repeat Kinesin PF00225.23 GAM17301.1 - 4.3e-111 371.0 1.3 1.2e-110 369.6 1.3 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAM17301.1 - 2.8e-27 95.5 0.8 1.2e-26 93.4 0.1 2.5 2 0 0 2 2 2 1 Microtubule binding APG6_N PF17675.1 GAM17301.1 - 0.011 16.2 8.7 0.011 16.2 8.7 5.4 1 1 4 5 5 5 0 Apg6 coiled-coil region Herpes_UL92 PF03048.14 GAM17301.1 - 0.051 13.4 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 UL92 family DUF1843 PF08898.10 GAM17301.1 - 4.6 7.8 16.0 9.5 6.8 0.3 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) Mto2_bdg PF12808.7 GAM17301.1 - 6.1 7.2 20.9 5.7 7.3 2.8 5.3 4 1 1 5 5 5 0 Micro-tubular organiser Mto1 C-term Mto2-binding region F-box-like PF12937.7 GAM17302.1 - 1.2e-09 37.9 0.1 3.2e-09 36.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM17302.1 - 3.1e-06 26.9 0.0 7.8e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain Sulfotransfer_1 PF00685.27 GAM17302.1 - 0.32 10.4 3.2 0.68 9.4 0.0 2.6 3 0 0 3 3 3 0 Sulfotransferase domain Trnau1ap PF17654.1 GAM17302.1 - 1.8 9.5 10.5 9.9 7.1 1.8 3.3 3 0 0 3 3 3 0 Selenocysteine tRNA 1 associated proteins ELMO_CED12 PF04727.13 GAM17303.1 - 8.3e-45 153.0 0.5 1.8e-44 151.9 0.5 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family Ank_2 PF12796.7 GAM17303.1 - 1.6e-24 86.3 8.2 1.3e-14 54.5 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM17303.1 - 5.4e-22 77.9 0.7 5e-13 49.3 0.0 5.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM17303.1 - 1.7e-20 72.5 5.1 3.6e-05 24.0 0.0 6.3 5 1 1 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 GAM17303.1 - 7e-19 65.9 1.5 6.7e-05 23.0 0.0 6.0 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAM17303.1 - 4.3e-18 65.1 7.7 1.6e-11 44.2 0.2 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) DUF3361 PF11841.8 GAM17303.1 - 9.8e-06 25.6 2.5 3e-05 24.0 2.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) MCM6_C PF18263.1 GAM17303.1 - 0.17 12.1 1.2 2.9 8.2 0.2 2.7 2 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain TRM13 PF05206.14 GAM17304.1 - 0.08 12.5 0.1 1.2 8.6 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase TRM13 Dickkopf_N PF04706.12 GAM17305.1 - 0.0025 18.3 18.4 0.0053 17.2 3.7 7.2 3 3 2 5 5 5 4 Dickkopf N-terminal cysteine-rich region EB PF01683.18 GAM17305.1 - 0.042 14.2 2.2 0.042 14.2 2.2 8.3 3 3 4 7 7 7 0 EB module UCH PF00443.29 GAM17306.1 - 3e-40 138.4 2.0 3e-40 138.4 2.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAM17306.1 - 2.7e-18 66.4 9.4 2e-08 34.8 0.0 4.9 4 0 0 4 4 4 3 DUSP domain UCH_1 PF13423.6 GAM17306.1 - 3.7e-14 53.1 3.3 1.5e-12 47.7 0.7 3.5 3 1 1 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 GAM17306.1 - 0.0044 16.7 0.1 0.018 14.8 0.1 2.1 1 0 0 1 1 1 1 Ubiquitin family CpXC PF14353.6 GAM17306.1 - 0.13 12.3 8.0 1 9.4 0.1 4.1 3 1 0 3 3 3 0 CpXC protein GFA PF04828.14 GAM17306.1 - 0.15 12.4 3.8 1.1 9.6 0.6 3.0 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF4110 PF13422.6 GAM17306.1 - 1.1 9.3 4.6 2.9 8.0 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) FNIP PF05725.12 GAM17307.1 - 3.2e-47 158.4 8.2 1.2e-11 44.6 0.1 4.7 2 1 3 5 5 5 5 FNIP Repeat LRR_8 PF13855.6 GAM17307.1 - 0.05 13.4 2.3 5.2 6.9 0.2 3.3 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 GAM17307.1 - 0.072 13.7 12.0 23 6.0 0.1 5.4 4 2 0 4 4 4 0 Leucine Rich Repeat WWE PF02825.20 GAM17308.1 - 1.9e-07 31.6 2.7 5.1e-07 30.2 2.7 1.8 1 0 0 1 1 1 1 WWE domain BRCT PF00533.26 GAM17308.1 - 0.0012 19.2 0.1 0.0041 17.5 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM17308.1 - 0.0019 18.5 0.3 0.0064 16.9 0.2 2.0 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain G-alpha PF00503.20 GAM17309.1 - 6.2e-119 397.3 2.0 7.4e-119 397.0 2.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM17309.1 - 5.7e-15 55.2 0.3 3.1e-11 43.0 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM17309.1 - 0.00016 21.1 0.3 0.069 12.5 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM17309.1 - 0.01 15.9 0.1 0.18 11.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 GAM17309.1 - 0.023 14.9 1.0 3.3 8.0 0.1 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 GAM17309.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain VID27 PF08553.10 GAM17310.1 - 2.5e-89 299.8 0.4 1.3e-88 297.5 0.4 1.9 1 1 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_PH PF17747.1 GAM17310.1 - 2.4e-13 50.3 1.0 1.8e-12 47.5 0.2 2.4 2 0 0 2 2 2 1 VID27 PH-like domain VID27_N PF17748.1 GAM17310.1 - 2.9e-11 43.5 0.2 2.9e-11 43.5 0.2 4.7 4 1 0 4 4 4 1 VID27 N-terminal region Imm30 PF15565.6 GAM17310.1 - 0.065 13.3 1.3 0.17 12.0 1.3 1.7 1 0 0 1 1 1 0 Immunity protein 30 FGase PF05013.12 GAM17311.1 - 0.0054 17.0 0.1 0.15 12.2 0.0 2.4 1 1 1 2 2 2 1 N-formylglutamate amidohydrolase Codanin-1_C PF15296.6 GAM17312.1 - 0.026 14.6 0.0 0.026 14.6 0.0 3.9 4 1 0 4 4 4 0 Codanin-1 C-terminus GRP PF07172.11 GAM17312.1 - 0.031 15.0 0.5 0.031 15.0 0.5 2.7 3 0 0 3 3 3 0 Glycine rich protein family SPC22 PF04573.12 GAM17313.1 - 1.8e-43 148.0 0.7 2.1e-43 147.7 0.7 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Ras PF00071.22 GAM17314.1 - 5.9e-45 152.8 0.0 7e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM17314.1 - 9e-21 74.3 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM17314.1 - 7.9e-06 25.4 0.0 1.3e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM17314.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RUN PF02759.19 GAM17315.1 - 5.3e-22 78.2 0.4 5.3e-22 78.2 0.4 2.9 3 0 0 3 3 3 1 RUN domain PH PF00169.29 GAM17315.1 - 0.09 13.3 0.2 0.49 10.9 0.0 2.4 2 0 0 2 2 2 0 PH domain DUF4407 PF14362.6 GAM17315.1 - 4 6.7 15.3 18 4.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CBP4 PF07960.11 GAM17315.1 - 8.9 6.2 15.2 0.1 12.4 0.8 2.8 2 0 0 2 2 2 0 CBP4 RhoGAP PF00620.27 GAM17316.1 - 2.5e-27 95.6 0.1 8.6e-27 93.8 0.1 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 GAM17316.1 - 3.4e-10 40.1 1.0 1.3e-09 38.1 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Mpp10 PF04006.12 GAM17318.1 - 5.7e-134 447.9 99.9 7.8e-134 447.4 99.9 1.2 1 0 0 1 1 1 1 Mpp10 protein ADK PF00406.22 GAM17319.1 - 2e-09 37.8 0.2 1.1e-08 35.3 0.2 2.4 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAM17319.1 - 0.00013 22.4 0.0 0.00061 20.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Chorion_2 PF03964.15 GAM17319.1 - 0.0054 17.5 6.7 0.032 15.1 0.0 2.8 1 1 1 2 2 2 1 Chorion family 2 TFIIA PF03153.13 GAM17319.1 - 1.6 8.6 18.3 2.6 7.9 18.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 GAM17319.1 - 1.9 7.8 12.7 0.95 8.8 7.1 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region SUIM_assoc PF16619.5 GAM17319.1 - 3.2 7.9 15.3 0.82 9.8 3.5 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RIFIN PF02009.16 GAM17321.1 - 0.86 9.4 4.1 1.3 8.9 4.1 1.2 1 0 0 1 1 1 0 Rifin DUF4397 PF14344.6 GAM17322.1 - 0.71 10.7 0.0 0.71 10.7 0.0 6.1 3 1 1 5 5 5 0 Domain of unknown function (DUF4397) TMEM154 PF15102.6 GAM17322.1 - 1.4 8.8 10.3 3.4 7.6 10.3 1.7 1 0 0 1 1 1 0 TMEM154 protein family RWD PF05773.22 GAM17324.1 - 4.4e-19 68.9 0.0 1.3e-18 67.4 0.0 1.8 1 1 0 1 1 1 1 RWD domain IBR PF01485.21 GAM17324.1 - 2.4e-15 56.5 46.1 7.6e-06 26.1 10.9 4.3 3 1 0 3 3 3 3 IBR domain, a half RING-finger domain DEC-1_N PF04625.13 GAM17324.1 - 4.6 6.1 7.8 6.6 5.6 7.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pkinase PF00069.25 GAM17325.1 - 2.3e-88 296.0 0.9 1.3e-42 146.0 0.1 3.8 3 2 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17325.1 - 3.6e-44 151.0 0.2 2.1e-14 53.5 0.1 4.3 4 0 0 4 4 4 4 Protein tyrosine kinase tRNA-synt_His PF13393.6 GAM17325.1 - 8.3e-18 64.7 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.22 GAM17325.1 - 2.4e-17 63.3 0.8 1.2e-16 61.0 0.8 2.4 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.7 GAM17325.1 - 6.5e-16 58.6 0.5 6.5e-16 58.6 0.5 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs HGTP_anticodon PF03129.20 GAM17325.1 - 1.9e-07 31.1 0.0 4.9e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Kinase-like PF14531.6 GAM17325.1 - 7.8e-05 22.1 1.6 0.44 9.8 0.0 5.0 6 0 0 6 6 6 1 Kinase-like FTA2 PF13095.6 GAM17325.1 - 9.8e-05 22.1 0.6 0.41 10.2 0.0 3.4 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAM17325.1 - 0.00025 20.5 1.6 0.65 9.3 0.0 2.8 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM17325.1 - 0.00032 20.7 0.3 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAM17325.1 - 0.014 15.0 0.8 0.092 12.3 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Serglycin PF04360.12 GAM17325.1 - 0.29 11.1 6.1 1.1 9.2 4.3 2.7 2 0 0 2 2 2 0 Serglycin GDPD PF03009.17 GAM17326.1 - 9.3e-31 107.5 0.0 9.3e-30 104.2 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 GAM17326.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF4419 PF14388.6 GAM17327.1 - 6.7e-81 272.0 1.0 6.7e-81 272.0 1.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4419) HSP20 PF00011.21 GAM17328.1 - 6.7e-17 61.5 1.8 6e-09 36.0 0.2 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM17328.1 - 5.5e-07 29.1 0.1 0.014 14.9 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA HMA PF00403.26 GAM17328.1 - 0.25 11.8 2.8 2 9.0 0.8 2.5 1 1 1 2 2 2 0 Heavy-metal-associated domain DUF4419 PF14388.6 GAM17329.1 - 1e-96 323.9 0.7 1e-96 323.9 0.7 1.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4419) FSA_C PF10479.9 GAM17329.1 - 2.4 6.2 12.2 4.1 5.4 12.2 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pkinase_Tyr PF07714.17 GAM17330.1 - 8.8e-62 208.7 0.0 1.2e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM17330.1 - 2.5e-48 164.8 0.0 3.4e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 GAM17330.1 - 1.4e-15 57.2 0.1 2.7e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 GAM17330.1 - 2.7e-05 23.3 0.0 0.00028 20.0 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 GAM17330.1 - 0.00043 20.3 0.0 0.00092 19.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 GAM17330.1 - 0.019 15.1 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Alpha_L_fucos PF01120.17 GAM17331.1 - 1.8e-116 389.4 3.8 2.2e-116 389.2 3.8 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 GAM17331.1 - 3.3e-19 69.2 0.2 9.8e-19 67.7 0.0 1.9 2 0 0 2 2 2 1 Alpha-L-fucosidase C-terminal domain Ribosomal_L4 PF00573.22 GAM17332.1 - 3.1e-53 180.3 0.6 5.5e-53 179.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family L51_S25_CI-B8 PF05047.16 GAM17333.1 - 9.9e-07 28.6 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Cyclin_N PF00134.23 GAM17334.1 - 2e-05 24.4 0.1 3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF5305 PF17231.2 GAM17334.1 - 0.0073 15.7 0.4 0.011 15.2 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Cyclin PF08613.11 GAM17334.1 - 0.049 14.0 0.1 0.049 14.0 0.1 2.2 2 0 0 2 2 2 0 Cyclin Mrr_cat_2 PF13156.6 GAM17334.1 - 0.14 12.1 0.5 0.33 10.9 0.2 1.8 2 0 0 2 2 2 0 Restriction endonuclease RRM_1 PF00076.22 GAM17335.1 - 3e-21 75.0 0.0 4.5e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM17335.1 - 0.00059 19.6 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 GAM17335.1 - 0.0051 16.4 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM17335.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4167 PF13763.6 GAM17336.1 - 0.081 13.1 0.2 0.27 11.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) Spc7 PF08317.11 GAM17336.1 - 0.32 9.8 23.3 0.89 8.4 23.3 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Baculo_p24 PF05073.12 GAM17336.1 - 0.89 9.3 14.5 0.16 11.7 6.8 2.1 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DUF1664 PF07889.12 GAM17336.1 - 1.2 9.1 13.1 0.83 9.7 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ORF6C PF10552.9 GAM17336.1 - 1.3 9.1 14.6 16 5.6 1.0 3.4 2 1 1 3 3 3 0 ORF6C domain End3 PF12761.7 GAM17336.1 - 2.5 8.3 23.0 0.19 11.9 9.3 2.1 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF2877 PF11392.8 GAM17336.1 - 4.8 7.9 5.5 31 5.3 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2877) Spectrin PF00435.21 GAM17336.1 - 5.2 7.6 17.9 11 6.5 9.4 2.5 1 1 1 2 2 2 0 Spectrin repeat TMPIT PF07851.13 GAM17337.1 - 8.4e-100 334.2 4.6 1e-99 333.9 4.6 1.0 1 0 0 1 1 1 1 TMPIT-like protein Laminin_II PF06009.12 GAM17337.1 - 0.087 12.8 3.0 0.13 12.3 3.0 1.2 1 0 0 1 1 1 0 Laminin Domain II Prominin PF05478.11 GAM17337.1 - 0.13 10.2 1.2 0.23 9.4 1.2 1.4 1 0 0 1 1 1 0 Prominin Syntaxin_2 PF14523.6 GAM17337.1 - 0.14 12.6 3.7 0.29 11.5 3.7 1.5 1 0 0 1 1 1 0 Syntaxin-like protein DUF812 PF05667.11 GAM17337.1 - 0.2 10.5 3.2 0.29 10.0 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF724 PF05266.14 GAM17337.1 - 0.32 10.8 3.6 0.57 10.0 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Med9 PF07544.13 GAM17337.1 - 0.63 10.2 5.0 2.9 8.0 1.1 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Macro PF01661.21 GAM17338.1 - 3.2e-32 111.0 0.2 5.5e-32 110.3 0.2 1.4 1 0 0 1 1 1 1 Macro domain WWE PF02825.20 GAM17338.1 - 7.1e-29 100.2 4.9 2e-09 37.9 0.1 3.6 3 0 0 3 3 3 3 WWE domain DUF4735 PF15882.5 GAM17340.1 - 0.077 12.4 0.0 0.098 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) Nucleo_P87 PF07267.11 GAM17340.1 - 0.09 11.6 0.5 0.097 11.5 0.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Rubella_E2 PF05749.11 GAM17340.1 - 0.16 11.4 3.2 0.2 11.1 3.2 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Med12-LCEWAV PF12145.8 GAM17342.1 - 3.2e-17 62.5 0.2 2.8e-16 59.4 0.0 2.6 2 0 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 GAM17342.1 - 1.1e-15 57.7 0.0 1.9e-14 53.7 0.0 2.8 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Serglycin PF04360.12 GAM17342.1 - 0.031 14.2 0.7 0.62 10.0 0.0 2.7 2 0 0 2 2 2 0 Serglycin TGF_beta_GS PF08515.12 GAM17342.1 - 6.6 6.3 7.1 0.58 9.7 0.9 2.6 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif FDF PF09532.10 GAM17343.1 - 2.5e-08 34.7 9.5 2.5e-08 34.7 9.5 3.0 3 0 0 3 3 3 1 FDF domain RAM PF15320.6 GAM17343.1 - 9.1 7.0 22.0 9 7.0 5.1 2.5 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein COX7a PF02238.15 GAM17344.1 - 0.041 14.3 0.0 0.041 14.3 0.0 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VII Yeast-kill-tox PF09207.11 GAM17344.1 - 0.069 13.8 1.1 0.095 13.4 1.1 1.2 1 0 0 1 1 1 0 Yeast killer toxin Lung_7-TM_R PF06814.13 GAM17345.1 - 1.9e-10 40.5 29.3 3.9e-10 39.5 29.3 1.5 1 1 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 GAM17345.1 - 9.2e-09 35.1 22.4 9.2e-09 35.1 22.4 2.0 2 1 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Asparaginase_2 PF01112.18 GAM17346.1 - 3.3e-35 121.6 6.9 2e-23 82.9 2.3 3.0 2 1 0 2 2 2 2 Asparaginase GEMIN8 PF15348.6 GAM17346.1 - 0.4 10.9 8.6 0.4 11.0 2.0 2.3 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 UTP25 PF06862.12 GAM17348.1 - 8.2e-163 542.5 13.2 1.2e-162 542.0 13.2 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Glyco_transf_7N PF13733.6 GAM17348.1 - 0.0011 18.6 1.6 0.0029 17.2 0.1 2.4 2 0 0 2 2 2 1 N-terminal region of glycosyl transferase group 7 DEAD PF00270.29 GAM17348.1 - 0.04 13.7 0.4 8 6.2 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase DUF4690 PF15756.5 GAM17349.1 - 0.00016 22.2 5.1 0.00018 22.1 3.4 2.0 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 GAM17349.1 - 0.00021 21.4 4.5 0.00058 20.0 4.5 1.7 1 0 0 1 1 1 1 Podoplanin DUF347 PF03988.12 GAM17349.1 - 2.1 8.6 5.6 2.5 8.4 1.9 2.7 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) DUF676 PF05057.14 GAM17350.1 - 2.3e-43 148.3 0.1 4.4e-43 147.3 0.1 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAM17350.1 - 6e-09 36.0 0.0 5.5e-07 29.5 0.0 2.5 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 GAM17350.1 - 1.5e-07 31.5 0.0 1.5e-07 31.5 0.0 1.7 2 1 0 2 2 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 GAM17350.1 - 3.3e-07 30.3 0.0 7.2e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 GAM17350.1 - 0.00023 20.5 0.0 0.00073 18.8 0.0 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 GAM17350.1 - 0.00087 18.9 0.0 0.0019 17.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 GAM17350.1 - 0.0029 17.2 0.0 0.017 14.7 0.0 2.2 2 1 0 2 2 2 1 Lipase (class 2) Abhydrolase_6 PF12697.7 GAM17350.1 - 0.0043 17.7 0.0 0.011 16.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM17350.1 - 0.0057 15.9 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAM17350.1 - 0.024 14.7 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 GAM17350.1 - 0.028 14.1 0.2 0.1 12.2 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold UPF0227 PF05728.12 GAM17350.1 - 0.042 13.8 0.1 0.1 12.5 0.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) BTB_2 PF02214.22 GAM17351.1 - 5.9e-16 58.6 0.0 8e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 GAM17352.1 - 6.2e-18 65.4 0.5 1.3e-17 64.3 0.5 1.6 1 0 0 1 1 1 1 TLD BTB_2 PF02214.22 GAM17352.1 - 4.1e-16 59.1 0.0 7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CSN7a_helixI PF18392.1 GAM17352.1 - 0.035 14.0 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain BAR PF03114.18 GAM17353.1 - 4.2e-15 56.1 3.2 6.2e-15 55.5 3.2 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 GAM17353.1 - 1.8e-14 53.1 0.1 3.3e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM17353.1 - 3.4e-14 52.4 0.0 5.4e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM17353.1 - 9.8e-12 44.4 0.0 1.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Herpes_UL6 PF01763.16 GAM17353.1 - 0.031 12.8 0.4 0.043 12.3 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Sec34 PF04136.15 GAM17353.1 - 0.091 12.6 1.3 1.9 8.3 0.1 2.2 1 1 1 2 2 2 0 Sec34-like family HHV-5_US34A PF17087.5 GAM17353.1 - 0.17 12.1 0.2 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus US34A protein family TPR_MLP1_2 PF07926.12 GAM17353.1 - 0.21 11.6 2.1 0.6 10.2 0.3 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MFS_1 PF07690.16 GAM17354.1 - 5.2e-23 81.5 26.7 9.5e-23 80.7 26.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAM17354.1 - 2.7e-22 79.1 9.6 2.7e-22 79.1 9.6 2.9 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.15 GAM17354.1 - 0.0005 19.2 1.0 0.0005 19.2 1.0 2.7 3 1 0 3 3 3 1 PUCC protein Sugar_tr PF00083.24 GAM17354.1 - 0.0015 17.4 6.4 0.0015 17.4 6.4 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter DUF1774 PF08611.10 GAM17354.1 - 9.1 6.7 7.5 5.7 7.3 0.1 3.3 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) Mnd1 PF03962.15 GAM17355.1 - 1.1e-23 83.2 0.1 2.9e-23 81.9 0.1 1.7 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 GAM17355.1 - 7.4e-13 48.4 1.4 7.4e-13 48.4 1.4 2.6 3 1 0 3 3 3 1 Leucine zipper with capping helix domain CheY-binding PF09078.11 GAM17355.1 - 0.0049 17.0 0.4 0.011 15.9 0.4 1.5 1 0 0 1 1 1 1 CheY binding GNAT_like PF18407.1 GAM17355.1 - 0.013 15.9 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyltransferase like domain FapA PF03961.13 GAM17355.1 - 0.034 12.8 2.7 0.037 12.6 2.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Flu_NS2 PF00601.19 GAM17355.1 - 0.039 14.2 1.3 0.064 13.6 0.4 1.8 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) Atg14 PF10186.9 GAM17355.1 - 0.052 12.6 4.6 0.086 11.9 4.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 S10_plectin PF03501.15 GAM17355.1 - 0.055 13.5 0.3 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 Plectin/S10 domain DivIC PF04977.15 GAM17355.1 - 0.058 13.2 13.4 0.85 9.4 3.5 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 GAM17355.1 - 0.17 11.2 4.7 0.19 11.1 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF848 PF05852.11 GAM17355.1 - 0.33 11.1 8.4 1.1 9.4 8.2 1.9 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Arf PF00025.21 GAM17356.1 - 3e-56 189.6 0.1 3.5e-56 189.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAM17356.1 - 2.3e-15 56.5 0.0 2.6e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM17356.1 - 5.2e-14 52.5 0.0 6.9e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM17356.1 - 1.6e-13 50.4 0.0 2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAM17356.1 - 8.9e-05 22.0 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 GAM17356.1 - 0.0011 18.3 0.3 1.3 8.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 GAM17356.1 - 0.0037 17.3 0.0 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.14 GAM17356.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.27 GAM17356.1 - 0.058 12.9 0.0 0.28 10.7 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 GAM17356.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 GAM17356.1 - 0.19 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PPR_2 PF13041.6 GAM17357.1 - 2e-21 75.9 13.8 0.0037 17.4 0.0 10.9 8 3 5 13 13 13 5 PPR repeat family PPR_3 PF13812.6 GAM17357.1 - 1.9e-14 53.5 8.9 0.0013 18.7 0.0 6.2 6 0 0 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.20 GAM17357.1 - 1e-12 47.4 6.8 0.41 11.0 0.0 9.4 10 0 0 10 10 10 4 PPR repeat PPR_long PF17177.4 GAM17357.1 - 3.5e-10 39.6 0.0 3.4e-05 23.3 0.0 3.7 1 1 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 GAM17357.1 - 0.099 12.7 1.2 14 5.9 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Senescence PF06911.12 GAM17358.1 - 3.4e-26 92.7 5.9 5.9e-26 91.9 5.9 1.4 1 0 0 1 1 1 1 Senescence-associated protein Ribosomal_L24e PF01246.20 GAM17359.1 - 6.8e-26 90.3 0.3 6.8e-26 90.3 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 GAM17359.1 - 0.042 13.4 1.3 0.046 13.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ribosomal_S8e PF01201.22 GAM17360.1 - 6e-49 165.7 3.1 7.6e-49 165.4 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Cytadhesin_P30 PF07271.11 GAM17360.1 - 0.22 11.0 0.2 0.31 10.6 0.2 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 DEP PF00610.21 GAM17361.1 - 4.6e-08 33.0 0.0 1.9e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PP2C_2 PF13672.6 GAM17361.1 - 0.0038 16.9 0.8 0.31 10.7 0.2 3.2 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 GAM17361.1 - 0.019 14.9 0.0 0.56 10.1 0.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Rubis-subs-bind PF09273.11 GAM17363.1 - 3.9e-17 63.1 1.8 3.6e-13 50.3 0.4 3.0 2 0 0 2 2 2 2 Rubisco LSMT substrate-binding SET PF00856.28 GAM17363.1 - 1.9e-08 34.9 1.1 3.3e-07 30.8 0.0 3.1 3 0 0 3 3 3 1 SET domain SUIM_assoc PF16619.5 GAM17363.1 - 5e-05 23.3 10.7 27 4.9 4.0 4.6 3 2 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 DUF3235 PF11574.8 GAM17363.1 - 0.059 14.2 2.8 0.79 10.6 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) CH PF00307.31 GAM17365.1 - 6.7e-15 55.2 0.2 8.2e-14 51.7 0.1 3.1 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM17365.1 - 0.051 13.4 0.0 0.21 11.5 0.0 2.2 1 0 0 1 1 1 0 CAMSAP CH domain Phage_tail_T PF06223.12 GAM17365.1 - 0.11 13.0 0.9 2.4 8.7 0.1 3.1 2 0 0 2 2 2 0 Minor tail protein T PsbY PF06298.11 GAM17366.1 - 0.073 13.0 0.3 0.073 13.0 0.3 2.2 2 1 0 2 2 2 0 Photosystem II protein Y (PsbY) PRCC PF10253.9 GAM17366.1 - 0.54 11.0 6.3 0.79 10.5 6.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pex14_N PF04695.13 GAM17366.1 - 4.9 7.8 11.2 6.8 7.3 9.7 2.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4706 PF15797.5 GAM17367.1 - 0.075 13.6 0.9 0.12 12.9 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4706) PCI PF01399.27 GAM17368.1 - 7.6e-11 42.5 2.6 9.5e-11 42.1 0.1 2.5 2 1 0 2 2 2 1 PCI domain Paf67 PF10255.9 GAM17369.1 - 2.4e-125 418.7 7.8 2.4e-125 418.7 7.8 1.4 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 PCI PF01399.27 GAM17369.1 - 0.00065 20.2 0.2 0.0021 18.6 0.2 1.8 1 0 0 1 1 1 1 PCI domain TPR_19 PF14559.6 GAM17369.1 - 0.0026 18.2 0.3 0.1 13.1 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM17369.1 - 0.033 14.3 2.1 0.065 13.4 0.6 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM17369.1 - 0.65 10.1 5.6 0.79 9.8 2.7 2.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat LSM PF01423.22 GAM17370.1 - 2.1e-19 68.9 0.2 2.6e-19 68.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain Cyclin_N PF00134.23 GAM17371.1 - 0.00014 21.6 0.1 0.00014 21.6 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain USP19_linker PF16602.5 GAM17371.1 - 1.2 9.6 4.2 0.59 10.7 1.9 1.6 2 0 0 2 2 2 0 Linker region of USP19 deubiquitinase Ribosomal_60s PF00428.19 GAM17371.1 - 2.9 8.6 5.7 11 6.7 2.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIA PF03153.13 GAM17371.1 - 7 6.5 23.8 10 6.0 23.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Actin PF00022.19 GAM17372.1 - 2.8e-33 115.1 0.0 6.8e-33 113.9 0.0 1.5 1 1 0 1 1 1 1 Actin RasGAP PF00616.19 GAM17373.1 - 1.2e-55 188.4 0.6 1.2e-55 188.4 0.6 2.8 2 1 1 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAM17373.1 - 9.9e-25 87.3 11.5 9.9e-25 87.3 11.5 2.3 2 0 0 2 2 2 1 RasGAP C-terminus MitMem_reg PF13012.6 GAM17373.1 - 0.12 12.8 5.4 1 9.8 0.4 3.5 3 1 0 3 3 3 0 Maintenance of mitochondrial structure and function Latarcin PF10279.9 GAM17373.1 - 0.14 12.6 4.8 0.77 10.2 1.4 2.9 2 0 0 2 2 2 0 Latarcin precursor Peptidase_S49_N PF08496.10 GAM17373.1 - 9.3 6.3 10.1 1.1 9.2 5.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-rbx1 PF12678.7 GAM17374.1 - 2.1e-25 88.8 13.6 2.9e-25 88.3 13.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAM17374.1 - 2.6e-17 62.6 10.5 3.4e-17 62.3 10.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 GAM17374.1 - 2.5e-06 27.7 15.0 0.0001 22.6 15.0 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM17374.1 - 0.00012 21.8 3.8 0.00012 21.8 3.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM17374.1 - 0.001 18.9 12.8 0.023 14.6 12.8 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAM17374.1 - 0.19 11.9 9.6 1.6 9.0 9.9 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 GAM17374.1 - 0.3 11.0 11.3 1.1 9.2 5.1 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAM17374.1 - 0.31 10.8 16.0 28 4.5 16.0 2.4 1 1 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 GAM17374.1 - 0.47 10.1 15.1 0.11 12.2 5.1 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 GAM17374.1 - 0.52 10.4 8.5 2.1 8.4 8.5 2.1 1 1 0 1 1 1 0 RING-type zinc-finger PGK PF00162.19 GAM17375.1 - 6e-149 496.1 1.2 6.8e-149 495.9 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3172 PF11371.8 GAM17375.1 - 0.052 13.3 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) Mucin PF01456.17 GAM17376.1 - 0.0042 17.1 2.3 0.0055 16.7 2.3 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.12 GAM17376.1 - 0.81 7.6 2.0 0.9 7.4 2.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tim17 PF02466.19 GAM17377.1 - 3.9e-06 27.2 0.6 4.2e-06 27.1 0.6 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family p450 PF00067.22 GAM17378.1 - 2.4e-66 224.4 0.3 4e-66 223.7 0.3 1.3 1 1 0 1 1 1 1 Cytochrome P450 Cation_ATPase_C PF00689.21 GAM17379.1 - 3.7e-11 43.1 11.4 3.7e-11 43.1 11.4 2.9 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAM17379.1 - 0.019 14.5 10.0 0.03 13.8 0.0 3.5 3 0 0 3 3 3 0 E1-E2 ATPase Hydrolase PF00702.26 GAM17379.1 - 0.022 15.1 0.0 0.39 11.0 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Med19 PF10278.9 GAM17379.1 - 1.6 8.7 25.4 3.6 7.5 9.0 2.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 EGF_2 PF07974.13 GAM17380.1 - 0.48 10.8 38.1 0.2 12.1 12.5 3.1 3 0 0 3 3 3 0 EGF-like domain ABC2_membrane PF01061.24 GAM17381.1 - 2.1e-87 291.9 69.0 3.2e-47 160.7 28.0 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAM17381.1 - 4.8e-38 130.8 0.0 1.1e-18 68.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAM17381.1 - 6.8e-30 102.8 12.2 1.1e-23 82.9 0.0 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 GAM17381.1 - 1.7e-11 43.9 50.2 9.8e-09 34.8 12.4 3.7 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 GAM17381.1 - 1.5e-08 35.1 0.0 3.3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 GAM17381.1 - 9.2e-07 28.9 0.3 0.00026 20.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 GAM17381.1 - 2.7e-06 27.0 0.9 0.0056 16.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM17381.1 - 2.9e-05 24.5 0.0 0.077 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAM17381.1 - 0.00074 19.4 0.0 1.8 8.3 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 GAM17381.1 - 0.0016 19.0 0.1 0.29 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM17381.1 - 0.0017 18.6 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAM17381.1 - 0.0051 16.4 0.1 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAM17381.1 - 0.026 14.9 0.1 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 GAM17381.1 - 0.032 14.4 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAM17381.1 - 0.035 14.2 0.4 8.2 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 GAM17381.1 - 0.041 13.6 0.2 3.6 7.3 0.3 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAM17381.1 - 0.11 12.4 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 GAM17381.1 - 0.12 12.6 1.4 1.5 9.1 0.4 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAM17381.1 - 0.17 11.5 1.7 1.3 8.6 0.6 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TPR_1 PF00515.28 GAM17382.1 - 6.7e-07 28.9 6.1 0.19 11.6 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM17382.1 - 1.4e-05 24.8 9.0 0.3 11.3 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM17382.1 - 5.7e-05 23.0 7.1 0.78 10.1 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat SGTA_dimer PF16546.5 GAM17382.1 - 0.0043 16.8 0.6 3.9 7.3 0.0 4.0 4 0 0 4 4 4 1 Homodimerisation domain of SGTA TPR_17 PF13431.6 GAM17382.1 - 0.005 17.1 9.2 16 6.2 0.4 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM17382.1 - 0.0089 15.4 0.2 0.0089 15.4 0.2 4.1 3 2 1 4 4 4 1 MalT-like TPR region TPR_14 PF13428.6 GAM17382.1 - 0.1 13.5 1.8 20 6.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM17382.1 - 0.18 12.1 15.9 1.4 9.2 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1206 PF06724.11 GAM17384.1 - 9.7e-11 41.6 19.6 0.00049 20.1 1.5 3.4 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) SCAMP PF04144.13 GAM17384.1 - 2 8.7 14.6 4.5 7.5 2.0 3.2 3 0 0 3 3 3 0 SCAMP family DUF5305 PF17231.2 GAM17384.1 - 3.7 6.9 7.1 2.8 7.3 1.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5305) EF-hand_7 PF13499.6 GAM17385.1 - 7.2e-08 32.8 1.2 1.1e-07 32.2 0.1 1.8 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM17385.1 - 2.3e-05 23.9 0.4 0.00028 20.6 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF_assoc_1 PF08355.12 GAM17385.1 - 0.0001 21.8 0.1 0.00017 21.1 0.1 1.4 1 0 0 1 1 1 1 EF hand associated EF-hand_1 PF00036.32 GAM17385.1 - 0.00024 20.4 0.0 0.00079 18.8 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 GAM17385.1 - 0.0008 18.8 0.0 0.0019 17.6 0.0 1.7 1 0 0 1 1 1 1 EF hand EF_assoc_2 PF08356.12 GAM17385.1 - 0.013 15.4 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 EF hand associated ABM PF03992.16 GAM17385.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase FMN_red PF03358.15 GAM17386.1 - 5.6e-28 97.6 0.0 8.5e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAM17386.1 - 1.2e-08 35.0 0.0 1.7e-08 34.4 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold Arm PF00514.23 GAM17387.1 - 1.5e-35 120.1 18.5 0.00032 20.6 0.0 12.8 13 1 0 13 13 13 9 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GAM17387.1 - 2.8e-17 61.3 21.8 0.095 13.0 0.0 10.5 12 0 0 12 12 12 6 HEAT repeat HEAT_2 PF13646.6 GAM17387.1 - 4.9e-15 55.7 0.5 0.0063 16.9 0.1 7.2 2 2 3 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 GAM17387.1 - 1.8e-12 47.5 8.3 0.028 14.9 0.1 8.4 6 3 3 9 9 9 4 HEAT-like repeat DUF3361 PF11841.8 GAM17387.1 - 1e-06 28.7 18.7 0.084 12.8 1.3 5.6 3 2 2 6 6 6 4 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 GAM17387.1 - 1.8e-06 28.0 15.6 0.054 13.6 0.1 6.4 4 2 4 8 8 8 2 V-ATPase subunit H RICTOR_V PF14668.6 GAM17387.1 - 0.013 15.7 1.7 0.68 10.2 0.0 4.4 5 1 0 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.9 GAM17387.1 - 0.015 15.3 16.3 2.8 8.0 0.1 5.9 5 3 2 7 7 7 0 Spinocerebellar ataxia type 10 protein domain Dicty_CTDC PF00526.18 GAM17388.1 - 2.1e-157 510.3 389.6 4.4e-12 45.7 12.7 19.5 20 0 0 20 20 20 19 Dictyostelium (slime mold) repeat Spore_YabQ PF09578.10 GAM17389.1 - 0.46 10.7 7.4 0.18 12.0 3.1 2.1 1 1 1 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) AA_kinase PF00696.28 GAM17390.1 - 5.3e-26 91.7 0.2 5.3e-26 91.7 0.2 1.9 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 GAM17390.1 - 3.1e-21 76.0 0.0 8e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAT PF04768.13 GAM17390.1 - 1.7e-13 50.6 0.0 3.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase LBP_BPI_CETP PF01273.25 GAM17390.1 - 0.00095 18.8 0.2 0.003 17.2 0.0 1.9 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain Sacchrp_dh_NADP PF03435.18 GAM17390.1 - 0.01 16.1 0.0 0.6 10.4 0.0 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain LRR_6 PF13516.6 GAM17391.1 - 3.5e-30 101.5 42.6 3.2e-05 23.6 0.1 11.6 11 0 0 11 11 11 10 Leucine Rich repeat LRR_4 PF12799.7 GAM17391.1 - 1e-11 44.9 42.3 0.02 15.3 0.8 7.5 5 2 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM17391.1 - 1.2e-06 28.2 31.5 1.5 9.7 2.0 10.3 9 2 0 9 9 9 3 Leucine Rich Repeat LRR_8 PF13855.6 GAM17391.1 - 0.00054 19.7 48.8 0.19 11.5 0.2 8.7 5 3 1 6 6 6 3 Leucine rich repeat YusW PF14039.6 GAM17391.1 - 0.065 13.8 0.3 21 5.7 0.0 3.3 3 0 0 3 3 3 0 YusW-like protein PhzC-PhzF PF02567.16 GAM17392.1 - 3.7e-51 174.2 0.0 4.4e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 GAM17392.1 - 9.2e-08 31.5 0.0 2.7e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Proline racemase Arf PF00025.21 GAM17393.1 - 2.6e-68 228.9 0.0 3e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAM17393.1 - 3.9e-16 59.0 0.0 4.7e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 GAM17393.1 - 9.5e-16 58.1 0.0 1.3e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM17393.1 - 7.6e-15 54.9 0.0 8.8e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAM17393.1 - 1.1e-10 41.2 0.4 9.1e-08 31.6 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAM17393.1 - 1.9e-07 30.7 0.0 2.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM17393.1 - 1.7e-06 28.1 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM17393.1 - 0.093 12.3 0.2 0.28 10.7 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.6 GAM17393.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM17393.1 - 0.16 12.5 0.0 1.7 9.2 0.0 2.1 1 1 0 1 1 1 0 ABC transporter Ank_2 PF12796.7 GAM17394.1 - 1.5e-32 112.0 14.7 3e-09 37.3 0.1 3.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM17394.1 - 2.9e-27 94.7 24.4 1e-06 29.2 0.1 5.6 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM17394.1 - 1.3e-22 79.5 13.5 0.0093 16.3 0.3 8.0 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM17394.1 - 1.8e-16 58.6 5.6 3.9 8.4 0.0 8.2 7 1 1 8 8 8 6 Ankyrin repeat Ank PF00023.30 GAM17394.1 - 0.00017 21.8 6.0 41 4.9 0.0 7.0 2 2 4 6 6 6 0 Ankyrin repeat DUF5049 PF16468.5 GAM17394.1 - 0.00085 19.2 0.4 32 4.5 0.0 5.8 7 1 1 8 8 8 0 Domain of unknown function (DUF5049) VHL_C PF17211.3 GAM17394.1 - 0.011 15.7 0.7 78 3.4 0.0 4.7 3 2 2 5 5 5 0 VHL box domain Prok-JAB PF14464.6 GAM17394.1 - 0.37 10.6 6.1 2.7 7.8 6.1 2.1 1 1 0 1 1 1 0 Prokaryotic homologs of the JAB domain Ank_4 PF13637.6 GAM17395.1 - 1.4e-26 92.5 10.5 3.3e-08 33.9 0.1 5.8 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM17395.1 - 7.2e-21 74.0 5.5 4.1e-07 30.2 0.2 4.3 3 1 0 3 3 3 3 Ankyrin repeats (many copies) RGS PF00615.19 GAM17395.1 - 7.3e-20 71.4 8.0 1.9e-15 57.2 0.2 3.7 4 0 0 4 4 4 2 Regulator of G protein signaling domain Ank_2 PF12796.7 GAM17395.1 - 5.9e-19 68.4 12.3 2.1e-07 31.4 0.5 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM17395.1 - 3.9e-16 57.5 4.5 0.0027 18.0 0.1 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 GAM17395.1 - 3.7e-15 55.6 2.9 0.0049 17.3 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat SOG2 PF10428.9 GAM17395.1 - 0.0005 19.4 26.1 0.00077 18.8 26.1 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein RTX PF02382.15 GAM17395.1 - 0.0076 16.0 0.2 0.0076 16.0 0.2 2.3 3 0 0 3 3 3 1 N-terminal domain in RTX protein Dala_Dala_lig_C PF07478.13 GAM17395.1 - 0.078 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus CppA_N PF14506.6 GAM17395.1 - 0.079 13.0 0.5 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 CppA N-terminal Mucin PF01456.17 GAM17395.1 - 0.35 10.9 29.0 0.9 9.5 29.0 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Hamartin PF04388.12 GAM17395.1 - 0.66 8.6 18.5 1.2 7.7 18.5 1.4 1 0 0 1 1 1 0 Hamartin protein Spatacsin_C PF14649.6 GAM17396.1 - 2.1e-94 316.0 5.7 3.7e-94 315.2 5.7 1.4 1 0 0 1 1 1 1 Spatacsin C-terminus BSMAP PF12280.8 GAM17397.1 - 0.0077 16.5 4.1 0.56 10.4 1.1 2.1 2 0 0 2 2 2 2 Brain specific membrane anchored protein Radial_spoke PF04712.12 GAM17397.1 - 0.015 14.3 8.9 0.072 12.0 0.4 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein FAM176 PF14851.6 GAM17397.1 - 0.16 11.6 13.5 0.24 11.1 0.2 2.3 2 0 0 2 2 2 0 FAM176 family NOA36 PF06524.12 GAM17397.1 - 0.59 9.4 28.7 0.62 9.3 10.9 2.2 2 0 0 2 2 2 0 NOA36 protein Sigma70_ner PF04546.13 GAM17397.1 - 0.65 9.8 15.9 1.5 8.6 2.5 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.6 GAM17397.1 - 0.92 9.8 24.8 1.7 8.9 5.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RXT2_N PF08595.11 GAM17397.1 - 1.4 8.9 15.9 2.3 8.2 5.4 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal TRAP_alpha PF03896.16 GAM17397.1 - 3.6 6.7 11.7 0.84 8.8 0.7 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 GAM17397.1 - 3.9 5.7 17.9 2.7 6.2 4.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Pox_Ag35 PF03286.14 GAM17397.1 - 4.8 6.9 17.8 1.1 9.0 3.0 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 GAM17397.1 - 7.6 7.0 28.4 0.43 11.0 4.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 GAM17397.1 - 9.4 4.2 16.2 1.6 6.7 6.3 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen TLP-20 PF06088.11 GAM17397.1 - 9.8 6.0 17.9 0.094 12.6 0.7 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) EloA-BP1 PF15870.5 GAM17399.1 - 7.4e-08 32.8 0.6 1.8e-07 31.5 0.6 1.7 1 0 0 1 1 1 1 ElonginA binding-protein 1 KIX_2 PF16987.5 GAM17399.1 - 0.0017 18.3 0.0 0.0047 16.9 0.0 1.8 1 0 0 1 1 1 1 KIX domain BUD22 PF09073.10 GAM17399.1 - 0.0084 15.5 10.8 0.0084 15.5 10.8 2.4 2 1 0 2 2 2 1 BUD22 Peptidase_M1 PF01433.20 GAM17401.1 - 2.6e-75 252.7 2.4 6.4e-75 251.5 2.4 1.7 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 GAM17401.1 - 1.3e-48 166.2 4.5 2.6e-48 165.2 4.5 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 GAM17401.1 - 1.3e-44 152.7 0.8 1.1e-42 146.4 0.3 2.5 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2463 PF09591.10 GAM17401.1 - 0.0065 16.4 2.1 0.015 15.2 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) DUF4744 PF15918.5 GAM17401.1 - 0.056 14.3 0.2 0.26 12.2 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Peptidase_M1 PF01433.20 GAM17402.1 - 2.2e-76 256.3 1.7 3.2e-76 255.7 1.2 1.5 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 GAM17402.1 - 4.1e-47 160.8 0.2 1.1e-46 159.4 0.2 1.8 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 GAM17402.1 - 5.3e-23 82.0 0.1 1.2e-22 80.9 0.1 1.6 1 0 0 1 1 1 1 ERAP1-like C-terminal domain FA_desaturase PF00487.24 GAM17402.1 - 0.035 14.0 0.5 2 8.2 0.1 2.3 2 0 0 2 2 2 0 Fatty acid desaturase MBOAT PF03062.19 GAM17403.1 - 2.1e-30 106.3 33.6 2.1e-30 106.3 33.6 1.8 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF2370 PF10176.9 GAM17403.1 - 0.0056 16.4 1.0 0.012 15.3 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Orf78 PF06024.12 GAM17403.1 - 0.02 15.2 0.3 0.02 15.2 0.3 2.2 2 0 0 2 2 2 0 Orf78 (ac78) LRRC37AB_C PF14914.6 GAM17403.1 - 7.5 6.4 7.1 0.37 10.7 1.3 1.8 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain VPS9 PF02204.18 GAM17404.1 - 2.7e-08 33.9 0.0 7.4e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SopA PF13981.6 GAM17404.1 - 0.019 15.4 1.3 0.17 12.3 0.1 2.8 2 0 0 2 2 2 0 SopA-like central domain GTA_holin_3TM PF11351.8 GAM17404.1 - 0.24 12.0 3.2 1.9 9.0 0.1 2.7 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Glycos_transf_1 PF00534.20 GAM17405.1 - 2.8e-07 30.2 0.0 6.5e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAM17405.1 - 7e-07 29.7 0.0 2e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAM17405.1 - 0.00023 21.6 0.1 0.00045 20.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 GAM17405.1 - 0.00097 19.2 0.4 0.0016 18.5 0.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 SR-25 PF10500.9 GAM17405.1 - 0.65 9.6 8.3 0.97 9.0 8.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RhoGAP-FF1 PF16512.5 GAM17406.1 - 0.005 17.5 0.4 0.015 16.0 0.4 1.9 1 0 0 1 1 1 1 p190-A and -B Rho GAPs FF domain zf-C3HC4_3 PF13920.6 GAM17406.1 - 0.012 15.5 15.6 0.012 15.5 15.6 3.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 GAM17406.1 - 0.062 14.2 0.4 0.062 14.2 0.4 6.0 6 1 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM17406.1 - 2.2 8.9 19.2 1.4 9.5 0.2 4.9 4 1 0 4 4 4 0 Zinc finger, C2H2 type PX PF00787.24 GAM17406.1 - 2.9 7.9 6.3 0.66 10.0 0.1 2.9 3 1 1 4 4 4 0 PX domain eIF2_C PF09173.11 GAM17407.1 - 7.8e-35 119.0 0.2 2.2e-34 117.6 0.2 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 GAM17407.1 - 8.9e-22 77.6 2.3 1.1e-20 74.0 2.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAM17407.1 - 3.7e-12 46.4 0.3 1.2e-11 44.8 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1_Xtn PF16897.5 GAM17407.1 - 0.015 15.3 0.1 0.032 14.3 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 GAM17407.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM17407.1 - 0.023 14.6 0.7 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase HI0933_like PF03486.14 GAM17408.1 - 6.2e-87 292.0 0.0 7.7e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 GAM17408.1 - 4e-06 26.2 0.2 0.12 11.4 0.0 3.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAM17408.1 - 4.5e-05 23.2 1.5 0.17 11.5 0.2 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM17408.1 - 0.00056 20.1 0.1 0.0018 18.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAM17408.1 - 0.001 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAM17408.1 - 0.0018 17.6 0.5 0.049 12.9 0.5 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 GAM17408.1 - 0.0018 17.1 0.3 0.11 11.2 0.1 2.1 2 0 0 2 2 2 2 MCRA family GIDA PF01134.22 GAM17408.1 - 0.041 13.0 1.5 4.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 GAM17408.1 - 0.15 11.3 0.0 0.42 9.8 0.0 1.7 1 0 0 1 1 1 0 Thi4 family DNase_II PF03265.15 GAM17409.1 - 5.3e-88 295.4 0.4 6e-88 295.2 0.4 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II C1_1 PF00130.22 GAM17410.1 - 0.00086 19.2 1.8 0.0021 17.9 1.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DDE_Tnp_1_7 PF13843.6 GAM17410.1 - 0.0028 17.0 0.0 0.0028 17.0 0.0 2.1 2 0 0 2 2 2 1 Transposase IS4 Prok-RING_1 PF14446.6 GAM17410.1 - 0.081 12.9 1.7 0.18 11.8 1.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 GAM17410.1 - 0.1 12.5 3.8 0.19 11.6 2.4 2.2 2 0 0 2 2 2 0 PHD-finger Dicty_CTDC PF00526.18 GAM17412.1 - 2e-10 40.4 28.1 3.1e-07 30.2 4.7 12.7 13 0 0 13 13 13 7 Dictyostelium (slime mold) repeat TMEM154 PF15102.6 GAM17412.1 - 0.23 11.3 3.5 0.39 10.6 3.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family Sporozoite_P67 PF05642.11 GAM17412.1 - 4.7 5.2 12.3 5 5.1 12.2 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Asp PF00026.23 GAM17413.1 - 2.2e-19 70.0 3.4 9.9e-19 67.9 3.4 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM17413.1 - 2.6e-12 47.4 1.1 5.7e-12 46.2 1.1 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAM17413.1 - 2.8e-11 43.5 0.0 9.2e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal DUF3443 PF11925.8 GAM17413.1 - 0.0011 17.9 0.6 0.011 14.6 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3443) Asp_protease_2 PF13650.6 GAM17413.1 - 0.14 12.8 0.1 7.5 7.3 0.0 3.2 4 0 0 4 4 4 0 Aspartyl protease PAP2_3 PF14378.6 GAM17414.1 - 0.087 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 PAP2 superfamily FNIP PF05725.12 GAM17415.1 - 4.2e-39 132.4 18.6 1.8e-08 34.4 0.3 7.0 5 2 1 7 7 7 7 FNIP Repeat PA14 PF07691.12 GAM17416.1 - 7.9e-30 103.6 3.2 3e-09 36.8 0.2 3.3 3 0 0 3 3 3 3 PA14 domain Dicty_CTDC PF00526.18 GAM17416.1 - 7.4e-05 22.6 10.2 7.4e-05 22.6 10.2 18.4 16 4 0 16 16 16 8 Dictyostelium (slime mold) repeat zf-CCHC PF00098.23 GAM17417.1 - 0.0067 16.5 2.1 0.015 15.4 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle TFIIA PF03153.13 GAM17417.1 - 0.87 9.5 52.1 0.03 14.3 42.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Adeno_PV PF03910.13 GAM17418.1 - 0.35 9.5 4.3 0.4 9.3 4.3 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF2749 PF10907.8 GAM17418.1 - 0.9 9.8 6.7 1.7 8.9 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) MHYT PF03707.16 GAM17418.1 - 2.1 8.6 13.8 0.4 10.9 8.1 2.1 1 1 1 2 2 2 0 Bacterial signalling protein N terminal repeat SUR7 PF06687.12 GAM17418.1 - 2.6 7.6 8.9 2.9 7.4 8.9 1.0 1 0 0 1 1 1 0 SUR7/PalI family DUF4342 PF14242.6 GAM17418.1 - 9.1 6.4 12.0 23 5.1 12.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Cyclin_N PF00134.23 GAM17419.1 - 2.2e-05 24.2 0.2 2.2e-05 24.2 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain IL13 PF03487.13 GAM17419.1 - 0.021 14.6 1.0 0.039 13.7 0.3 1.7 2 0 0 2 2 2 0 Interleukin-13 MCM PF00493.23 GAM17420.1 - 1.3e-100 335.1 0.0 2e-100 334.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAM17420.1 - 2.1e-35 121.3 1.0 4e-35 120.4 1.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAM17420.1 - 9.8e-26 90.0 0.4 4.7e-25 87.8 0.1 2.4 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 GAM17420.1 - 9.3e-12 45.5 1.1 2.4e-11 44.1 1.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAM17420.1 - 3.8e-07 29.7 0.1 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAM17420.1 - 6.4e-06 26.2 0.0 2.8e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAM17420.1 - 0.00082 19.2 0.0 0.009 15.9 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAM17420.1 - 0.17 11.6 0.0 25 4.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain CPSase_L_D2 PF02786.17 GAM17422.1 - 2.3e-78 262.5 0.1 4.1e-78 261.7 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAM17422.1 - 3.7e-45 153.0 0.1 7.9e-45 151.9 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAM17422.1 - 2.5e-38 130.5 0.0 7.1e-38 129.0 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAM17422.1 - 4e-16 58.6 0.2 9.5e-16 57.4 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 GAM17422.1 - 8.4e-10 39.1 0.1 2.1e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 GAM17422.1 - 3.3e-09 36.6 0.0 1.7e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAM17422.1 - 1e-07 31.7 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAM17422.1 - 7.7e-06 26.0 0.0 1.9e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.6 GAM17422.1 - 0.00085 18.8 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 GAM17422.1 - 0.0047 16.7 0.1 0.076 12.8 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like ATPgrasp_ST PF14397.6 GAM17422.1 - 0.0058 15.9 0.0 0.023 14.0 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp PP_kinase_N PF13089.6 GAM17422.1 - 0.1 13.0 0.1 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain RnfC_N PF13375.6 GAM17422.1 - 0.12 12.4 0.0 0.4 10.7 0.0 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DHR-2 PF06920.13 GAM17423.1 - 2.9e-163 544.3 10.4 4.7e-163 543.6 10.4 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 GAM17423.1 - 1.1e-47 162.3 7.5 4.3e-47 160.5 3.2 3.1 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins PA14 PF07691.12 GAM17424.1 - 3.6e-05 23.6 0.0 8.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 GAM17424.1 - 0.00054 19.8 21.5 0.0035 17.2 4.4 14.5 13 2 0 14 14 14 6 Dictyostelium (slime mold) repeat Sporozoite_P67 PF05642.11 GAM17424.1 - 0.046 11.8 5.9 0.075 11.1 5.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM154 PF15102.6 GAM17424.1 - 0.61 10.0 14.2 1 9.3 14.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family ATF7IP_BD PF16788.5 GAM17424.1 - 4.3 7.4 11.2 8.6 6.4 11.2 1.5 1 0 0 1 1 1 0 ATF-interacting protein binding domain Membr_traf_MHD PF10540.9 GAM17425.1 - 0.0082 16.3 1.7 0.038 14.2 0.5 2.6 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain Thioredoxin PF00085.20 GAM17426.1 - 2e-35 120.9 0.4 3.1e-25 88.1 0.1 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 GAM17426.1 - 7.8e-17 61.8 7.7 1.1e-07 31.9 0.1 3.1 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 GAM17426.1 - 1.4e-09 38.4 0.2 0.0004 20.8 0.1 3.4 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAM17426.1 - 2.2e-07 31.1 1.3 0.38 11.1 0.0 4.2 3 2 1 4 4 4 3 Thioredoxin-like OST3_OST6 PF04756.13 GAM17426.1 - 7.3e-06 25.5 0.5 0.004 16.6 0.1 2.5 1 1 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 GAM17426.1 - 0.0047 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like ERp29_N PF07912.13 GAM17426.1 - 0.008 16.3 0.1 0.14 12.3 0.0 2.5 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_5 PF13743.6 GAM17426.1 - 0.0085 15.8 0.3 2.5 7.8 0.0 3.2 2 1 1 3 3 3 1 Thioredoxin AMH_N PF04709.12 GAM17426.1 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region DUF1764 PF08576.10 GAM17427.1 - 5.3e-21 75.4 4.5 5.3e-21 75.4 4.5 3.0 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) BAF1_ABF1 PF04684.13 GAM17427.1 - 0.0037 16.4 19.9 0.0049 16.0 19.9 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor MAP65_ASE1 PF03999.12 GAM17427.1 - 0.35 9.5 23.7 0.43 9.2 23.7 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SWI-SNF_Ssr4 PF08549.10 GAM17427.1 - 0.87 8.2 17.7 1 7.9 17.7 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Hamartin PF04388.12 GAM17427.1 - 1.5 7.4 20.4 1.8 7.2 20.4 1.0 1 0 0 1 1 1 0 Hamartin protein Glyco_hydro_15 PF00723.21 GAM17429.1 - 1.1e-36 126.7 0.0 2.5e-36 125.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 DUF4566 PF15130.6 GAM17429.1 - 0.045 13.2 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4566) Tam41_Mmp37 PF09139.11 GAM17431.1 - 1.2e-90 304.3 2.9 1.7e-90 303.8 2.9 1.2 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DUF202 PF02656.15 GAM17432.1 - 6.6e-19 68.1 0.5 6.6e-19 68.1 0.5 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) ATPase_gene1 PF09527.10 GAM17432.1 - 0.0058 16.8 3.4 0.02 15.0 0.1 2.2 2 0 0 2 2 2 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Pex14_N PF04695.13 GAM17432.1 - 0.023 15.4 1.9 0.023 15.4 1.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.9 GAM17432.1 - 0.08 13.2 3.2 0.15 12.3 0.3 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF3040 PF11239.8 GAM17432.1 - 1 9.7 4.0 2 8.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Spt20 PF12090.8 GAM17432.1 - 1.6 8.2 13.2 2.2 7.8 13.2 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 GAM17432.1 - 1.6 7.4 9.4 2.1 7.1 9.4 1.1 1 0 0 1 1 1 0 Androgen receptor YajC PF02699.15 GAM17432.1 - 7.9 6.4 9.6 0.47 10.4 4.0 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit DP PF08781.10 GAM17433.1 - 2.4e-32 111.7 3.6 7.7e-32 110.1 3.6 1.8 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 GAM17433.1 - 1.2e-19 70.1 0.4 1.2e-19 70.1 0.4 2.0 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Mucin PF01456.17 GAM17433.1 - 0.068 13.2 15.5 0.16 12.0 15.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 GAM17433.1 - 0.36 11.3 6.2 1.2 9.6 6.2 1.9 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DNA_pol_B_2 PF03175.13 GAM17437.1 - 0.00034 19.6 0.0 0.00047 19.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral He_PIG PF05345.12 GAM17438.1 - 0.14 12.3 0.3 0.23 11.7 0.3 1.3 1 0 0 1 1 1 0 Putative Ig domain Peptidase_S49_N PF08496.10 GAM17438.1 - 2 8.5 6.2 2.6 8.1 6.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Mucin PF01456.17 GAM17440.1 - 0.0092 16.0 6.7 0.011 15.7 6.7 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.12 GAM17440.1 - 0.073 11.1 1.6 0.076 11.0 1.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 GAM17440.1 - 4.1 7.4 13.0 6.2 6.8 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.11 GAM17440.1 - 5.8 6.8 7.8 8.1 6.3 7.8 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SSP160 PF06933.11 GAM17440.1 - 6.1 4.9 12.5 7.7 4.6 12.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ATPgrasp_N PF18130.1 GAM17442.1 - 0.012 16.2 0.1 0.012 16.1 0.1 1.0 1 0 0 1 1 1 0 ATP-grasp N-terminal domain OMPdecase PF00215.24 GAM17443.1 - 7e-74 248.2 0.5 1.1e-73 247.5 0.5 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 GAM17443.1 - 1.4e-11 44.2 0.2 2.6e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GST_N_2 PF13409.6 GAM17444.1 - 5.9e-16 58.5 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM17444.1 - 6e-13 48.6 0.0 9.2e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM17444.1 - 9.5e-08 32.2 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM17444.1 - 0.00046 20.3 0.0 0.00077 19.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM17444.1 - 0.015 15.7 0.0 0.21 12.0 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAM17444.1 - 0.028 14.2 0.1 0.071 12.9 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Metallophos_C PF14008.6 GAM17445.1 - 1.3e-20 74.0 1.7 2.2e-19 70.0 0.7 2.8 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 GAM17445.1 - 9.3e-16 58.9 1.1 1.9e-15 57.9 1.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GAM17445.1 - 1.2e-14 54.7 0.7 1.2e-14 54.7 0.7 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain fn3_PAP PF17808.1 GAM17445.1 - 2.7e-05 24.2 0.1 0.00015 21.9 0.1 2.2 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase WD40 PF00400.32 GAM17446.1 - 7.6e-50 165.8 27.9 9e-05 23.2 0.1 11.1 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17446.1 - 6.9e-19 67.9 6.7 2.6e-05 24.5 0.0 7.7 4 2 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 GAM17446.1 - 2.4e-16 59.9 0.3 4.6e-16 59.1 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 GAM17446.1 - 6.1e-09 35.6 0.1 0.0036 16.7 0.0 3.9 3 1 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 GAM17446.1 - 2.2e-08 33.2 6.8 0.0011 17.7 0.0 4.8 5 0 0 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAM17446.1 - 8.9e-06 24.7 5.7 0.00027 19.8 0.1 4.6 3 2 2 5 5 5 1 Nup133 N terminal like Ge1_WD40 PF16529.5 GAM17446.1 - 1.9e-05 23.8 7.1 2.3 7.1 0.0 6.7 3 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.5 GAM17446.1 - 0.0028 16.3 0.0 0.71 8.4 0.0 2.9 3 0 0 3 3 3 2 beta-propeller of ELYS nucleoporin PALB2_WD40 PF16756.5 GAM17446.1 - 0.016 14.1 4.0 0.91 8.4 0.0 4.3 5 0 0 5 5 5 0 Partner and localizer of BRCA2 WD40 domain WRKY PF03106.15 GAM17447.1 - 5.8e-44 148.2 17.5 1.1e-22 80.0 6.0 3.4 3 0 0 3 3 3 2 WRKY DNA -binding domain TPR_2 PF07719.17 GAM17448.1 - 3.1e-14 51.8 14.0 0.00012 21.9 0.2 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAM17448.1 - 2e-13 49.6 15.6 1.7e-05 24.4 0.2 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM17448.1 - 1.1e-10 41.6 10.1 8.6e-05 22.8 0.0 4.6 4 1 0 5 5 5 3 Tetratricopeptide repeat SET PF00856.28 GAM17448.1 - 1.3e-10 41.9 1.7 1.3e-10 41.9 1.7 2.5 2 1 0 2 2 2 1 SET domain TPR_8 PF13181.6 GAM17448.1 - 9.7e-07 28.5 15.2 0.079 13.2 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat zf-MYND PF01753.18 GAM17448.1 - 5.4e-05 23.2 11.6 5.4e-05 23.2 11.6 3.6 4 1 0 4 4 1 1 MYND finger TPR_14 PF13428.6 GAM17448.1 - 0.00079 20.0 0.8 15 6.7 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM17448.1 - 0.00086 19.8 1.0 0.25 12.1 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM17448.1 - 0.019 15.6 0.7 17 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM17448.1 - 0.071 13.0 5.4 2.2 8.2 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM17448.1 - 0.1 13.2 1.1 9.8 6.8 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM17448.1 - 0.11 12.5 0.7 18 5.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM17448.1 - 0.6 9.8 5.4 0.21 11.3 0.6 2.6 3 0 0 3 3 3 0 TPR repeat DUF4252 PF14060.6 GAM17448.1 - 0.78 9.6 3.7 6.6 6.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) SR-25 PF10500.9 GAM17448.1 - 1.8 8.1 6.2 6 6.4 6.2 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RasGAP PF00616.19 GAM17449.1 - 1.1e-23 84.1 0.1 7.9e-14 51.9 0.0 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.18 GAM17449.1 - 3.9e-18 65.6 0.0 1.4e-17 63.8 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 GAM17449.1 - 3.3e-05 24.1 0.1 0.0001 22.5 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) DUF1242 PF06842.12 GAM17451.1 - 0.63 9.9 5.8 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) WASH_WAHD PF11945.8 GAM17452.1 - 8.8e-47 160.0 3.7 1.2e-46 159.5 3.7 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex Str_synth PF03088.16 GAM17453.1 - 3.3e-18 65.6 0.0 3.5e-17 62.3 0.0 2.7 3 1 0 3 3 3 1 Strictosidine synthase SGL PF08450.12 GAM17453.1 - 2.2e-16 60.2 0.0 1.8e-15 57.2 0.0 2.2 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 GAM17453.1 - 9.8e-06 25.4 0.7 0.33 11.1 0.0 4.6 4 0 0 4 4 4 2 NHL repeat Arylesterase PF01731.20 GAM17453.1 - 0.0014 18.8 0.0 0.0058 16.8 0.0 2.0 2 0 0 2 2 2 1 Arylesterase LSM PF01423.22 GAM17454.1 - 3.1e-14 52.4 0.3 4.9e-14 51.8 0.3 1.3 1 0 0 1 1 1 1 LSM domain Coiled PF05710.12 GAM17455.1 - 3.7e-11 43.7 4.8 4e-11 43.6 4.8 1.0 1 0 0 1 1 1 1 Coiled coil Pinin_SDK_N PF04697.13 GAM17456.1 - 0.078 13.6 2.4 0.59 10.8 0.1 2.6 2 0 0 2 2 2 0 pinin/SDK conserved region Cwf_Cwc_15 PF04889.12 GAM17456.1 - 0.08 12.7 5.1 0.016 14.9 1.7 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein INCENP_ARK-bind PF03941.15 GAM17456.1 - 0.32 10.9 4.7 1.2 9.1 4.5 2.1 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region RhoGAP PF00620.27 GAM17457.1 - 4.4e-47 159.7 0.1 8.5e-47 158.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 GAM17457.1 - 5.5e-39 133.5 1.6 1.3e-38 132.3 1.6 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GAM17457.1 - 8.4e-12 45.1 0.8 2.1e-11 43.8 0.8 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2810 PF10928.8 GAM17457.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) zf-UBR PF02207.20 GAM17458.1 - 6.3e-18 64.7 11.9 1.3e-17 63.8 11.9 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) PurA PF04845.13 GAM17459.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein ELL PF10390.9 GAM17459.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL FNIP PF05725.12 GAM17460.1 - 3e-80 264.1 5.0 5e-14 52.2 0.0 12.1 9 2 3 13 13 13 12 FNIP Repeat IPK PF03770.16 GAM17462.1 - 8.5e-49 166.1 0.2 1.1e-48 165.7 0.2 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase COMM_domain PF07258.14 GAM17463.1 - 8.7e-21 73.8 0.1 2.2e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 COMM domain FNIP PF05725.12 GAM17464.1 - 6.2e-09 35.9 12.3 9.5e-05 22.5 0.6 5.3 5 2 0 5 5 5 4 FNIP Repeat AmoC PF04896.12 GAM17466.1 - 0.0029 16.9 0.6 0.0038 16.5 0.6 1.3 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C Herpes_US9 PF06072.11 GAM17466.1 - 2.6 8.0 5.7 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Inhibitor_I29 PF08246.12 GAM17468.1 - 7e-10 39.2 0.0 2e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Tic110 PF16940.5 GAM17468.1 - 0.21 10.1 3.7 0.27 9.7 3.7 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter CRAL_TRIO PF00650.20 GAM17469.1 - 7.6e-46 155.7 0.1 1.1e-45 155.2 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM17469.1 - 2e-10 40.7 0.3 5.7e-10 39.2 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAM17469.1 - 6.5e-08 32.8 0.1 1.1e-07 32.1 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain LIM_bind PF01803.16 GAM17470.1 - 6.9e-32 110.9 0.1 6.9e-32 110.9 0.1 3.4 2 1 1 3 3 2 1 LIM-domain binding protein DUF2722 PF10846.8 GAM17470.1 - 0.0011 18.0 4.1 0.0011 18.0 4.1 3.0 2 1 0 3 3 2 1 Protein of unknown function (DUF2722) YkpC PF17447.2 GAM17470.1 - 0.025 15.3 1.2 0.16 12.8 1.2 2.6 1 0 0 1 1 1 0 Uncharacterized YkpC-like Presenilin PF01080.17 GAM17470.1 - 0.063 12.0 14.1 0.54 9.0 0.2 2.3 2 0 0 2 2 2 0 Presenilin EPL1 PF10513.9 GAM17470.1 - 0.099 13.0 0.2 0.099 13.0 0.2 2.6 3 1 0 3 3 1 0 Enhancer of polycomb-like Neur_chan_memb PF02932.16 GAM17470.1 - 0.26 11.3 16.7 1.5 8.8 8.7 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 GAM17470.1 - 0.29 11.1 2.5 13 5.6 0.2 2.3 2 0 0 2 2 2 0 N-glycosylation protein eIF-3_zeta PF05091.12 GAM17470.1 - 0.33 9.9 21.4 0.19 10.7 5.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 GAM17470.1 - 0.92 9.4 53.0 0.51 10.3 15.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 GAM17470.1 - 1.4 9.1 13.2 3.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Glt_symporter PF03616.14 GAM17470.1 - 2.5 6.7 4.0 1.8 7.2 0.0 2.0 2 0 0 2 2 2 0 Sodium/glutamate symporter DUF4770 PF15994.5 GAM17470.1 - 3 8.1 27.6 0.5 10.6 2.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) DUF702 PF05142.12 GAM17470.1 - 3.2 8.2 18.8 0.94 10.0 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DivIC PF04977.15 GAM17470.1 - 6 6.7 22.9 0.18 11.6 7.9 2.8 2 0 0 2 2 2 0 Septum formation initiator TFB6 PF17110.5 GAM17470.1 - 7.7 6.2 8.1 6 6.6 0.4 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH RR_TM4-6 PF06459.12 GAM17470.1 - 9.6 5.9 22.5 5 6.9 1.4 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 GAM17471.1 - 0.54 9.6 10.6 5.3 6.3 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Hydin_ADK PF17213.3 GAM17472.1 - 0.0097 16.2 6.0 0.0097 16.2 6.0 3.3 2 1 1 3 3 3 1 Hydin Adenylate kinase-like domain VPS9 PF02204.18 GAM17473.1 - 4.3e-21 75.1 1.8 1.1e-20 73.8 0.3 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain OKR_DC_1_N PF03709.15 GAM17473.1 - 0.097 13.0 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain SRP54_N PF02881.19 GAM17473.1 - 0.11 12.8 0.2 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain DUF4419 PF14388.6 GAM17474.1 - 5.7e-97 324.8 0.2 6.7e-97 324.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Metallophos_C PF14008.6 GAM17475.1 - 6.8e-22 78.1 4.2 1e-21 77.5 0.4 3.1 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 GAM17475.1 - 9.3e-19 67.8 2.1 9.3e-19 67.8 2.1 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 GAM17475.1 - 2.3e-16 60.9 1.3 2.3e-16 60.9 1.3 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase fn3_PAP PF17808.1 GAM17475.1 - 2.3e-06 27.7 0.0 0.00069 19.7 0.0 3.2 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase DUF4469 PF14734.6 GAM17476.1 - 0.0051 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4469) with IG-like fold RepA1_leader PF08048.12 GAM17476.1 - 2.7 8.4 5.8 10 6.5 2.1 2.4 2 0 0 2 2 2 0 Tap RepA1 leader peptide VIT_2 PF13757.6 GAM17478.1 - 0.18 11.7 0.0 0.18 11.7 0.0 1.9 2 1 0 2 2 2 0 Vault protein inter-alpha-trypsin domain DUF4469 PF14734.6 GAM17479.1 - 0.00096 19.3 0.1 0.0019 18.3 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4469) with IG-like fold EFG_C PF00679.24 GAM17479.1 - 0.024 14.7 0.1 0.055 13.5 0.1 1.7 1 1 0 1 1 1 0 Elongation factor G C-terminus DUF4469 PF14734.6 GAM17480.1 - 0.012 15.8 0.0 0.029 14.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold DUF1775 PF07987.11 GAM17480.1 - 0.074 13.3 0.0 0.8 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unkown function (DUF1775) TRAM_LAG1_CLN8 PF03798.16 GAM17481.1 - 2.9e-39 134.9 28.2 2.9e-39 134.9 28.2 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 GAM17481.1 - 0.073 12.7 3.8 0.12 12.0 0.7 2.7 2 0 0 2 2 2 0 TRAM1-like protein FNIP PF05725.12 GAM17482.1 - 6.3e-17 61.5 5.9 0.00016 21.8 0.0 5.3 4 2 2 6 6 6 5 FNIP Repeat T2SSN PF01203.19 GAM17482.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein N SNARE PF05739.19 GAM17483.1 - 1.2e-12 47.6 0.1 1.2e-12 47.6 0.1 1.9 2 0 0 2 2 2 1 SNARE domain Tex_N PF09371.10 GAM17483.1 - 0.017 14.8 1.0 0.017 14.8 1.0 2.1 2 0 0 2 2 2 0 Tex-like protein N-terminal domain ABC2_membrane_3 PF12698.7 GAM17483.1 - 0.018 14.2 2.1 0.023 13.8 2.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Syntaxin PF00804.25 GAM17483.1 - 0.022 14.4 12.9 0.036 13.7 3.8 2.2 2 0 0 2 2 2 0 Syntaxin MCPsignal PF00015.21 GAM17483.1 - 0.026 14.3 2.1 0.026 14.3 2.1 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ZFYVE21_C PF16696.5 GAM17483.1 - 0.029 14.2 0.5 0.068 13.0 0.5 1.6 1 0 0 1 1 1 0 Zinc finger FYVE domain-containing protein 21 C-terminus TssO PF17561.2 GAM17483.1 - 0.031 14.4 2.2 0.031 14.4 2.2 3.1 2 1 1 3 3 3 0 Type VI secretion system, TssO Laminin_II PF06009.12 GAM17483.1 - 0.21 11.6 6.8 0.94 9.5 0.9 2.3 2 0 0 2 2 2 0 Laminin Domain II Prominin PF05478.11 GAM17483.1 - 0.48 8.3 11.9 0.015 13.3 3.2 1.9 1 1 1 2 2 2 0 Prominin Borrelia_orfA PF02414.15 GAM17483.1 - 0.98 9.0 13.7 0.11 12.1 7.4 1.9 1 1 1 2 2 2 0 Borrelia ORF-A Med11 PF10280.9 GAM17483.1 - 3.3 8.2 9.6 0.6 10.6 1.6 2.5 3 0 0 3 3 3 0 Mediator complex protein SUR7 PF06687.12 GAM17484.1 - 0.0014 18.3 2.3 0.0023 17.6 2.3 1.5 1 0 0 1 1 1 1 SUR7/PalI family Zip PF02535.22 GAM17484.1 - 0.046 12.9 2.4 0.063 12.5 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3124 PF11322.8 GAM17484.1 - 0.1 12.8 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) DUF373 PF04123.13 GAM17485.1 - 0.0048 16.4 1.1 0.0052 16.3 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF373) DUF1461 PF07314.11 GAM17485.1 - 0.04 13.8 0.4 0.071 13.0 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1461) Lipoprotein_15 PF03640.15 GAM17486.1 - 1.7e-52 174.7 6.5 2.4e-12 46.2 0.1 6.2 6 0 0 6 6 6 6 Secreted repeat of unknown function PepSY_TM PF03929.16 GAM17488.1 - 2.6 7.6 9.4 0.73 9.4 0.9 2.3 2 0 0 2 2 2 0 PepSY-associated TM region CCDC53 PF10152.9 GAM17488.1 - 2.9 8.3 30.6 0.1 13.1 7.5 2.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex L31 PF09784.9 GAM17490.1 - 0.051 14.0 0.7 0.051 14.0 0.7 2.7 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 HMMR_N PF15905.5 GAM17490.1 - 0.8 9.1 28.4 0.12 11.8 22.0 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 GAM17490.1 - 0.93 9.9 8.6 0.77 10.2 0.9 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 GAM17490.1 - 0.98 8.7 10.5 0.99 8.7 9.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Gastrin PF00918.17 GAM17490.1 - 2 9.4 9.2 0.48 11.4 4.8 2.1 2 1 0 2 2 2 0 Gastrin/cholecystokinin family DUF641 PF04859.12 GAM17490.1 - 2.3 8.6 19.7 0.088 13.1 3.8 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) KxDL PF10241.9 GAM17490.1 - 6.4 7.1 17.1 0.92 9.8 10.5 2.9 2 1 2 4 4 4 0 Uncharacterized conserved protein A_deaminase PF00962.22 GAM17491.1 - 5e-123 410.6 0.1 6.7e-123 410.2 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MIP PF00230.20 GAM17492.1 - 7.1e-54 182.9 17.8 8.3e-54 182.7 17.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2721 PF11026.8 GAM17492.1 - 0.96 9.3 11.4 0.64 9.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Sulfate_transp PF00916.20 GAM17493.1 - 2.9e-95 319.3 19.9 4.1e-95 318.7 19.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAM17493.1 - 3.5e-17 62.1 0.1 6.2e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAM17493.1 - 0.014 15.7 4.4 0.014 15.7 4.4 3.8 3 2 1 4 4 4 0 Molybdate transporter of MFS superfamily DUF1365 PF07103.11 GAM17494.1 - 3.1e-50 171.1 0.0 5.2e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) CMAS PF02353.20 GAM17494.1 - 1.3e-13 50.9 0.1 6.5e-10 38.8 0.0 2.8 3 0 0 3 3 3 2 Mycolic acid cyclopropane synthetase RRM_1 PF00076.22 GAM17495.1 - 3.2e-23 81.3 0.1 3.5e-10 39.5 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM17495.1 - 9.6e-11 41.4 0.0 8.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM17495.1 - 3.9e-06 26.6 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif CBS PF00571.28 GAM17497.1 - 1.5e-20 73.3 5.0 6.7e-11 42.5 0.4 2.5 2 1 0 2 2 2 2 CBS domain EF-G-binding_N PF07299.11 GAM17497.1 - 0.031 14.8 2.3 1.7 9.3 0.1 2.8 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal DisA_N PF02457.16 GAM17497.1 - 0.092 12.3 0.2 0.16 11.6 0.1 1.5 1 1 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding DEAD PF00270.29 GAM17498.1 - 1.2e-42 145.6 4.5 3e-42 144.4 0.1 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM17498.1 - 1.4e-27 96.2 0.8 1.4e-27 96.2 0.8 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF1477 PF07346.11 GAM17498.1 - 0.043 14.1 0.6 0.13 12.6 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) RNase_T PF00929.24 GAM17500.1 - 4e-09 37.2 0.1 1.7e-08 35.2 0.0 2.1 2 1 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 GAM17500.1 - 0.002 17.9 0.4 0.021 14.5 0.3 2.5 1 1 0 1 1 1 1 3'-5' exonuclease Orthopox_A43R PF06517.11 GAM17500.1 - 0.031 14.1 0.5 0.031 14.1 0.5 1.7 2 0 0 2 2 2 0 Orthopoxvirus A43R protein DUF3530 PF12048.8 GAM17500.1 - 0.041 13.3 2.0 3.5 6.9 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3530) DUF5063 PF16702.5 GAM17500.1 - 0.086 13.2 0.1 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) SOG2 PF10428.9 GAM17500.1 - 0.89 8.7 9.8 0.16 11.2 3.8 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein ORC6 PF05460.13 GAM17501.1 - 0.012 14.9 6.4 0.015 14.6 6.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Transposase_21 PF02992.14 GAM17501.1 - 0.023 14.0 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Transposase family tnp2 MAJIN PF15077.6 GAM17501.1 - 0.22 11.3 3.2 0.3 10.8 3.2 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein Macoilin PF09726.9 GAM17501.1 - 0.3 9.6 6.3 0.31 9.6 6.3 1.1 1 0 0 1 1 1 0 Macoilin family CCDC24 PF15669.5 GAM17501.1 - 0.41 10.5 6.5 0.65 9.8 6.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Dicty_REP PF05086.12 GAM17501.1 - 0.61 8.0 8.2 0.82 7.6 8.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein adh_short PF00106.25 GAM17502.1 - 1.4e-39 135.6 2.5 1.4e-39 135.6 2.5 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM17502.1 - 1.5e-31 109.8 10.2 3.1e-31 108.7 4.2 2.8 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 GAM17502.1 - 1e-23 83.7 0.3 2.3e-23 82.6 0.3 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 GAM17502.1 - 9e-18 64.8 1.0 1.8e-17 63.9 1.0 1.4 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.6 GAM17502.1 - 0.00042 20.6 0.2 0.0007 19.9 0.2 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal RmlD_sub_bind PF04321.17 GAM17502.1 - 0.078 12.1 0.3 0.34 10.0 0.6 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain GST_N_3 PF13417.6 GAM17504.1 - 6.8e-11 42.4 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM17504.1 - 1.3e-10 41.3 0.0 2.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM17504.1 - 2.6e-09 37.3 0.0 6.4e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM17504.1 - 4.1e-09 36.7 0.1 7.4e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM17504.1 - 1.6e-08 34.4 0.0 2.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM17504.1 - 1.7e-07 31.4 0.2 3e-07 30.5 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_28 PF02636.17 GAM17505.1 - 1.3e-69 234.8 0.0 2e-69 234.2 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PI31_Prot_N PF11566.8 GAM17506.1 - 2.4e-18 66.5 0.0 3.4e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 GAM17506.1 - 1.7e-12 48.4 15.4 1.7e-12 48.4 15.4 2.5 3 0 0 3 3 3 1 PI31 proteasome regulator PALP PF00291.25 GAM17507.1 - 2.7e-67 227.3 0.0 4e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 GAM17507.1 - 1.4e-15 57.5 0.0 5.4e-09 36.4 0.0 3.2 2 1 0 2 2 2 2 CBS domain DUF4449 PF14613.6 GAM17508.1 - 1.7e-07 31.5 0.6 3.2e-07 30.6 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) F_actin_bind PF08919.10 GAM17509.1 - 0.051 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 F-actin binding RasGAP PF00616.19 GAM17511.1 - 3.3e-32 111.9 0.2 2.7e-18 66.5 0.4 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase DUF547 PF04784.14 GAM17511.1 - 6.1e-24 84.4 0.0 2.1e-23 82.7 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function, DUF547 FAM92 PF06730.11 GAM17511.1 - 0.042 13.3 0.1 0.14 11.6 0.1 1.8 1 0 0 1 1 1 0 FAM92 protein Bromodomain PF00439.25 GAM17512.1 - 9.7e-21 73.6 1.8 1.1e-20 73.5 0.3 1.9 2 0 0 2 2 2 1 Bromodomain DUF4618 PF15397.6 GAM17512.1 - 0.0065 15.9 0.2 0.084 12.3 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) DUF325 PF03804.13 GAM17512.1 - 0.016 15.2 2.5 0.85 9.7 0.0 3.3 2 1 1 3 3 3 0 Viral proteins of unknown function Phasin PF05597.11 GAM17512.1 - 0.026 14.5 1.4 0.053 13.5 0.3 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Biotin_carb_C PF02785.19 GAM17512.1 - 0.035 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain DivIC PF04977.15 GAM17512.1 - 0.3 10.9 1.7 0.94 9.3 0.9 2.1 1 1 0 1 1 1 0 Septum formation initiator Syntaxin-6_N PF09177.11 GAM17512.1 - 2.7 8.6 7.9 0.18 12.4 1.7 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Macoilin PF09726.9 GAM17512.1 - 4.5 5.7 17.6 0.2 10.2 11.7 1.6 2 0 0 2 2 2 0 Macoilin family GATase_7 PF13537.6 GAM17513.1 - 4.4e-10 39.5 0.0 9e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAM17513.1 - 4.8e-10 39.7 0.0 1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 GAM17513.1 - 1e-09 38.1 0.0 1.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAM17513.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase GATase_4 PF13230.6 GAM17513.1 - 0.2 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II NAT PF04768.13 GAM17514.1 - 1.1e-31 109.7 0.0 2.9e-31 108.4 0.0 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 GAM17514.1 - 7.1e-08 32.3 0.0 5.2e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Amino acid kinase family Zip PF02535.22 GAM17514.1 - 0.0015 17.8 0.7 0.0015 17.8 0.7 2.2 1 1 1 2 2 2 1 ZIP Zinc transporter FAM176 PF14851.6 GAM17514.1 - 0.38 10.4 4.5 1.1 8.9 4.5 1.8 1 0 0 1 1 1 0 FAM176 family DUF4834 PF16118.5 GAM17514.1 - 0.98 10.4 9.3 0.19 12.7 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) WRNPLPNID PF15017.6 GAM17514.1 - 3 8.8 8.8 12 6.9 8.8 2.1 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box PBP1_TM PF14812.6 GAM17515.1 - 0.006 16.9 1.5 0.006 16.9 1.5 2.8 2 1 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal ATP-synt_D PF01813.17 GAM17515.1 - 0.16 11.7 4.0 0.62 9.9 0.1 2.5 3 0 0 3 3 3 0 ATP synthase subunit D LAP1C PF05609.12 GAM17515.1 - 5.3 6.0 21.3 6.4 5.8 21.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ndc1_Nup PF09531.10 GAM17515.1 - 7.4 5.1 14.7 9.4 4.8 14.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MAPKK1_Int PF08923.10 GAM17516.1 - 1.2e-30 105.8 0.3 1.4e-30 105.6 0.3 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting RWP-RK PF02042.15 GAM17518.1 - 2e-23 82.1 0.0 3.8e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HlyIII PF03006.20 GAM17519.1 - 6.7e-49 166.6 18.0 8.7e-49 166.2 18.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 GAM17519.1 - 0.0011 19.1 0.0 0.0069 16.5 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF962) Ceramidase PF05875.12 GAM17519.1 - 0.11 12.0 18.1 6.2 6.2 18.1 2.2 1 1 0 1 1 1 0 Ceramidase Hat1_N PF10394.9 GAM17520.1 - 1.6e-41 142.2 0.9 1.6e-41 142.2 0.9 1.9 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 GAM17520.1 - 7.1e-05 23.0 0.0 0.00021 21.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM17520.1 - 0.00096 19.1 0.1 0.045 13.7 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 GAM17520.1 - 0.0015 18.2 0.4 0.0054 16.4 0.2 1.9 2 0 0 2 2 2 1 MOZ/SAS family Acetyltransf_7 PF13508.7 GAM17520.1 - 0.0066 16.9 0.0 0.029 14.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain cEGF PF12662.7 GAM17521.1 - 5.3 7.1 6.1 6.5 6.8 0.8 3.0 3 0 0 3 3 3 0 Complement Clr-like EGF-like RasGEF PF00617.19 GAM17522.1 - 4e-56 190.0 0.5 4e-56 190.0 0.5 2.5 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 GAM17522.1 - 3.4e-21 75.4 1.2 3.3e-20 72.3 0.6 3.1 3 0 0 3 3 3 1 RasGEF N-terminal motif SwrA PF17423.2 GAM17522.1 - 2.4 8.2 6.5 0.43 10.6 0.4 2.7 2 1 1 3 3 3 0 Swarming motility protein Ribosomal_S24e PF01282.19 GAM17523.1 - 9.2e-30 102.4 1.8 9.9e-30 102.3 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S24e CSN8_PSD8_EIF3K PF10075.9 GAM17524.1 - 1e-27 96.9 0.0 1.6e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PTEN_C2 PF10409.9 GAM17525.1 - 1.3e-19 70.2 0.0 2.1e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 GAM17525.1 - 3.3e-10 39.9 0.0 5.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM17525.1 - 5e-07 29.5 0.0 2.2e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAM17525.1 - 0.044 13.8 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family SDA1 PF05285.12 GAM17526.1 - 0.0041 16.6 28.3 0.0053 16.2 12.9 2.1 2 0 0 2 2 2 2 SDA1 SR-25 PF10500.9 GAM17526.1 - 0.0044 16.7 15.4 0.0044 16.7 15.4 3.4 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein DUF572 PF04502.13 GAM17526.1 - 2.2 7.8 31.0 0.67 9.5 8.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Methyltransf_12 PF08242.12 GAM17526.1 - 5.3 7.9 7.3 14 6.5 1.1 2.5 2 0 0 2 2 2 0 Methyltransferase domain Fz PF01392.22 GAM17527.1 - 4.2e-05 24.1 5.4 9.4e-05 23.0 5.4 1.6 1 0 0 1 1 1 1 Fz domain Acyl-CoA_dh_1 PF00441.24 GAM17528.1 - 2.3e-26 92.8 0.8 3.9e-26 92.1 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAM17528.1 - 5.5e-22 78.6 0.0 1.1e-21 77.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAM17528.1 - 2.7e-20 72.3 0.0 4.7e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM17528.1 - 1.1e-08 35.5 0.0 2.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_8 PF05148.15 GAM17529.1 - 5.2e-80 268.4 1.8 7.8e-80 267.8 1.8 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 GAM17529.1 - 3.5e-07 30.8 0.3 1.7e-06 28.6 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM17529.1 - 6.7e-05 23.5 0.1 0.0063 17.2 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM17529.1 - 0.0002 21.0 0.2 0.0013 18.3 0.1 2.1 1 1 1 2 2 2 1 Methyltransferase small domain Siah-Interact_N PF09032.11 GAM17529.1 - 0.003 17.8 4.2 0.003 17.8 4.2 2.3 3 0 0 3 3 3 1 Siah interacting protein, N terminal Methyltransf_32 PF13679.6 GAM17529.1 - 0.24 11.4 0.0 0.24 11.4 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain FAM60A PF15396.6 GAM17529.1 - 5.8 6.9 8.8 11 6.0 8.8 1.4 1 0 0 1 1 1 0 Protein Family FAM60A WD40 PF00400.32 GAM17530.1 - 1.2e-32 111.4 21.1 3.3e-05 24.5 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 GAM17530.1 - 6.5e-11 42.0 0.0 1.6e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM17530.1 - 2.6e-05 24.0 0.0 7.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 GAM17530.1 - 3.7e-05 23.2 1.7 1.3 8.3 0.1 3.4 2 2 0 3 3 3 3 WD40-like domain Nup160 PF11715.8 GAM17530.1 - 0.014 14.0 19.3 1.7 7.2 0.1 5.7 1 1 4 6 6 6 0 Nucleoporin Nup120/160 F-box_4 PF15966.5 GAM17530.1 - 0.041 13.8 4.3 0.063 13.2 0.0 3.3 4 0 0 4 4 4 0 F-box DUF4550 PF15084.6 GAM17530.1 - 0.055 13.9 1.4 0.25 11.8 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4550) FNIP PF05725.12 GAM17531.1 - 9e-27 93.0 6.4 8e-10 38.7 0.0 8.1 6 2 2 8 8 8 6 FNIP Repeat LRR_1 PF00560.33 GAM17531.1 - 0.014 15.8 2.7 6 7.8 0.0 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat DcrB PF08786.11 GAM17531.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 DcrB FNIP PF05725.12 GAM17532.1 - 1.2e-18 67.0 26.9 4.5e-12 45.9 0.4 6.0 3 2 0 4 4 4 3 FNIP Repeat PP_kinase_C PF13090.6 GAM17533.1 - 4.9e-60 201.9 0.0 9.3e-60 201.0 0.0 1.4 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain 2 PP_kinase PF02503.17 GAM17533.1 - 1e-59 201.6 0.2 5.9e-59 199.1 0.1 2.1 2 0 0 2 2 2 1 Polyphosphate kinase middle domain PP_kinase_C_1 PF17941.1 GAM17533.1 - 1.4e-58 197.2 0.5 4.6e-58 195.5 0.1 2.0 1 1 1 2 2 2 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_N PF13089.6 GAM17533.1 - 3.1e-14 53.2 0.3 9.2e-14 51.7 0.3 1.9 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 GAM17533.1 - 7.9e-13 48.4 0.3 1.4e-07 31.4 0.1 2.9 2 1 0 2 2 2 2 PLD-like domain FNIP PF05725.12 GAM17534.1 - 2.7e-23 81.8 6.2 2.8e-10 40.2 0.0 6.7 5 1 1 6 6 6 5 FNIP Repeat DUF1769 PF08588.10 GAM17534.1 - 0.0034 17.6 0.2 7.2 6.9 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1769) FNIP PF05725.12 GAM17535.1 - 6.1e-28 96.7 26.6 1.4e-11 44.3 1.0 7.5 6 3 3 9 9 9 5 FNIP Repeat LRR_6 PF13516.6 GAM17535.1 - 0.13 12.4 4.4 12 6.3 0.1 5.2 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 GAM17535.1 - 6.5 7.7 9.1 25 6.0 0.0 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat WD40 PF00400.32 GAM17536.1 - 8.3e-05 23.3 6.2 0.017 16.0 0.3 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat FNIP PF05725.12 GAM17537.1 - 4.2e-17 62.0 18.2 3.4e-06 27.1 0.0 7.6 6 2 2 8 8 8 7 FNIP Repeat FNIP PF05725.12 GAM17538.1 - 6.5e-13 48.6 19.6 3.6e-05 23.8 0.1 7.3 6 2 0 8 8 8 5 FNIP Repeat Stealth_CR2 PF11380.8 GAM17539.1 - 2.3e-35 121.0 1.2 4.7e-35 120.0 1.2 1.5 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 GAM17539.1 - 1.4e-09 37.5 0.0 2.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 GAM17539.1 - 4.4e-08 32.9 0.9 1.8e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 GAM17539.1 - 1.1e-06 28.4 0.3 2.9e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 FNIP PF05725.12 GAM17540.1 - 1e-27 96.0 8.0 8e-10 38.7 0.5 7.5 5 2 2 7 7 7 6 FNIP Repeat Ras PF00071.22 GAM17541.1 - 1.1e-58 197.5 0.0 1.2e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM17541.1 - 1.7e-20 73.4 0.0 2.4e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM17541.1 - 1.2e-08 34.6 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM17541.1 - 6.5e-06 25.8 0.2 5e-05 22.9 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM17541.1 - 0.00017 21.6 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM17541.1 - 0.00037 20.5 0.1 0.69 9.8 0.2 2.4 1 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 GAM17541.1 - 0.023 14.5 0.5 0.32 10.7 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 GAM17541.1 - 0.042 13.1 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 GAM17541.1 - 0.079 12.5 0.0 0.87 9.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B TPP_enzyme_M PF00205.22 GAM17541.1 - 0.095 12.4 0.0 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain FNIP PF05725.12 GAM17542.1 - 3.3e-07 30.4 6.5 0.017 15.3 0.1 6.1 4 2 1 6 6 6 3 FNIP Repeat Ras PF00071.22 GAM17543.1 - 1.7e-57 193.5 0.0 2e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM17543.1 - 7e-20 71.4 0.0 1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM17543.1 - 6.4e-08 32.2 0.0 7.1e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM17543.1 - 3.5e-05 23.4 0.1 0.00035 20.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM17543.1 - 0.0001 22.3 0.1 0.5 10.3 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM17543.1 - 0.0016 18.5 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 GAM17543.1 - 0.0083 15.9 0.3 0.18 11.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein ParA PF10609.9 GAM17543.1 - 0.028 13.9 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAM17543.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FeoB_N PF02421.18 GAM17543.1 - 0.12 12.0 0.0 0.69 9.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF2139 PF09910.9 GAM17543.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) TPR_8 PF13181.6 GAM17544.1 - 0.037 14.3 1.2 0.25 11.7 0.5 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM17544.1 - 0.056 13.3 0.2 0.19 11.6 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-CCCH PF00642.24 GAM17545.1 - 1.9e-09 37.2 20.0 9.3e-05 22.2 3.4 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAM17545.1 - 4.4e-07 29.6 17.2 0.0016 18.2 3.1 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger SAM_1 PF00536.30 GAM17545.1 - 6.4e-07 29.7 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf_CCCH_4 PF18345.1 GAM17545.1 - 3.3e-06 27.0 28.0 7e-05 22.7 4.5 3.7 3 1 0 3 3 3 2 Zinc finger domain Torus PF16131.5 GAM17545.1 - 0.0025 18.5 1.0 0.0025 18.5 1.0 4.1 1 1 3 4 4 4 2 Torus domain SAM_2 PF07647.17 GAM17545.1 - 0.0064 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-CCCH_2 PF14608.6 GAM17545.1 - 0.032 14.7 1.8 0.032 14.7 1.8 3.8 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 GAM17545.1 - 0.93 9.7 25.4 0.28 11.4 1.1 3.5 2 1 1 3 3 3 0 Zinc-finger containing family SAM_1 PF00536.30 GAM17546.1 - 1.2e-07 32.0 0.0 2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM17546.1 - 3.6e-07 30.2 0.0 7.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CagA PF03507.13 GAM17546.1 - 0.00036 20.5 0.1 0.00045 20.2 0.1 1.1 1 0 0 1 1 1 1 CagA exotoxin TFIIA PF03153.13 GAM17546.1 - 0.34 10.8 12.4 0.38 10.7 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0697 PF15117.6 GAM17546.1 - 0.41 10.7 2.9 0.8 9.8 2.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 zf-CCCH PF00642.24 GAM17547.1 - 8.9e-09 35.1 32.6 0.00013 21.8 4.3 3.9 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAM17547.1 - 1.1e-06 28.5 8.4 0.00058 19.8 0.7 4.0 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 GAM17547.1 - 2e-05 24.3 25.1 0.015 15.1 0.4 3.9 4 0 0 4 4 4 3 CCCH-type zinc finger Torus PF16131.5 GAM17547.1 - 0.0057 17.3 27.8 0.041 14.6 0.5 3.9 1 1 3 4 4 4 3 Torus domain Imm6 PF14434.6 GAM17547.1 - 0.055 13.4 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Immunity protein Imm6 Nop14 PF04147.12 GAM17547.1 - 0.96 7.6 5.7 0.99 7.5 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family zf-CCCH_2 PF14608.6 GAM17547.1 - 8.7 7.0 32.0 2.5 8.7 1.3 4.9 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 GAM17548.1 - 5.3e-23 80.4 45.4 0.0003 20.6 4.7 6.2 6 0 0 6 6 6 6 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAM17548.1 - 8.8e-21 73.3 63.4 5.5e-05 23.1 4.4 6.3 6 0 0 6 6 6 6 Zinc finger domain Torus PF16131.5 GAM17548.1 - 4.7e-18 65.9 42.8 0.00045 20.9 1.8 6.8 5 2 2 7 7 7 6 Torus domain zf-CCCH_3 PF15663.5 GAM17548.1 - 3.3e-09 37.0 31.9 0.072 13.3 0.0 6.7 6 0 0 6 6 6 5 Zinc-finger containing family SAM_1 PF00536.30 GAM17548.1 - 3.6e-07 30.5 0.2 6.2e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM17548.1 - 3.5e-05 23.8 0.0 7.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-CCCH_4 PF18044.1 GAM17548.1 - 0.00034 20.3 50.6 0.014 15.2 3.1 6.1 6 0 0 6 6 6 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAM17548.1 - 0.016 15.7 58.2 0.35 11.4 1.8 7.1 6 1 1 7 7 7 0 RNA-binding, Nab2-type zinc finger SAM_PNT PF02198.16 GAM17548.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain ubiquitin PF00240.23 GAM17549.1 - 3.9e-166 539.1 27.6 1.1e-32 111.5 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 GAM17549.1 - 4.4e-77 253.9 26.9 8.3e-15 54.4 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAM17549.1 - 4.7e-27 94.3 14.3 0.00093 19.6 0.1 7.0 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 GAM17549.1 - 8.6e-18 64.1 7.1 0.085 12.8 0.0 5.3 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAM17549.1 - 1.9e-17 63.4 11.9 0.059 13.7 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM17549.1 - 2e-16 60.1 3.9 0.29 11.2 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAM17549.1 - 1.7e-15 57.4 1.6 0.66 10.6 0.0 5.2 1 1 2 5 5 5 5 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 GAM17549.1 - 3.5e-08 33.1 2.1 2.3 7.5 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase DUF2870 PF11069.8 GAM17549.1 - 1.6e-07 31.6 0.0 40 4.7 0.0 5.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 GAM17549.1 - 5.1e-07 29.7 29.5 34 4.6 0.0 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_3_3 PF13750.6 GAM17549.1 - 7e-07 29.0 0.1 27 4.4 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) DUF969 PF06149.12 GAM17549.1 - 1.4e-05 24.7 0.1 28 4.1 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF969) DUF3861 PF12977.7 GAM17549.1 - 1.5e-05 25.1 3.3 48 4.2 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) UDP-g_GGTase PF06427.11 GAM17549.1 - 1.7e-05 24.9 7.8 9.6 6.4 0.1 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF3435 PF11917.8 GAM17549.1 - 5.5e-05 22.3 1.1 30 3.4 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3435) Big_7 PF17957.1 GAM17549.1 - 6.6e-05 23.6 0.2 1.5e+02 3.3 0.0 5.0 5 0 0 5 5 5 0 Bacterial Ig domain Corona_NS2A PF05213.12 GAM17549.1 - 0.0002 20.8 0.1 58 2.9 0.0 4.8 5 0 0 5 5 5 0 Coronavirus NS2A protein ACT_5 PF13710.6 GAM17549.1 - 0.00047 20.0 5.7 56 3.7 0.0 5.2 5 0 0 5 5 5 0 ACT domain ORF11CD3 PF10549.9 GAM17549.1 - 0.00055 20.0 1.8 1.2e+02 2.9 0.0 6.3 10 0 0 10 10 5 0 ORF11CD3 domain YcgR_2 PF12945.7 GAM17549.1 - 0.00074 19.6 10.3 40 4.4 0.1 5.2 5 0 0 5 5 5 0 Flagellar protein YcgR ACT_4 PF13291.6 GAM17549.1 - 0.0017 18.9 0.7 2.4e+02 2.4 0.0 5.0 5 0 0 5 5 5 0 ACT domain Imm12 PF15560.6 GAM17549.1 - 0.0026 17.7 3.6 1e+02 2.9 0.0 4.9 5 0 0 5 5 5 0 Immunity protein 12 NEAT PF05031.12 GAM17549.1 - 0.036 14.7 8.8 22 5.7 0.6 4.5 1 1 3 4 4 4 0 Iron Transport-associated domain Glyco_tran_WecB PF03808.13 GAM17549.1 - 0.074 13.0 0.0 2.7e+02 1.4 0.0 4.3 5 0 0 5 5 5 0 Glycosyl transferase WecB/TagA/CpsF family ProRS-C_2 PF09181.10 GAM17549.1 - 2.8 8.1 9.1 2.6e+02 1.8 0.1 4.8 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal PH_15 PF17339.2 GAM17549.1 - 7.8 6.5 10.9 1.2e+02 2.7 0.1 4.4 5 0 0 5 5 5 0 PH domain FNIP PF05725.12 GAM17550.1 - 9.6e-18 64.1 12.8 4.4e-08 33.2 0.1 6.1 5 1 0 5 5 5 3 FNIP Repeat FNIP PF05725.12 GAM17551.1 - 1.9e-22 79.1 11.9 6.7e-09 35.8 0.1 6.1 4 2 2 6 6 6 5 FNIP Repeat ATG7_N PF16420.5 GAM17552.1 - 1e-86 291.3 0.0 5.5e-86 288.9 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 GAM17552.1 - 1.1e-35 123.1 0.0 5.4e-35 120.9 0.0 1.8 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.20 GAM17552.1 - 0.016 15.3 0.0 0.29 11.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 GAM17552.1 - 0.031 13.6 0.0 1.3 8.4 0.0 2.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain APG17 PF04108.12 GAM17553.1 - 8.5e-07 28.4 1.2 8.5e-07 28.4 1.2 6.1 3 1 2 5 5 5 2 Autophagy protein Apg17 ubiquitin PF00240.23 GAM17553.1 - 1.7e-05 24.5 0.2 1.7e-05 24.5 0.2 6.8 6 0 0 6 6 6 1 Ubiquitin family Lebercilin PF15619.6 GAM17553.1 - 0.0011 18.6 37.8 0.0011 18.6 37.8 8.0 3 1 4 7 7 7 2 Ciliary protein causing Leber congenital amaurosis disease Rad60-SLD PF11976.8 GAM17553.1 - 0.0042 16.9 0.0 0.054 13.3 0.0 3.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like NT-C2 PF10358.9 GAM17554.1 - 5.7e-09 35.8 6.8 3.3e-08 33.4 6.8 2.4 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins LMBR1 PF04791.16 GAM17554.1 - 0.056 12.3 9.9 0.1 11.5 9.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Orf78 PF06024.12 GAM17554.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.2 2 1 0 2 2 2 0 Orf78 (ac78) UPF0242 PF06785.11 GAM17554.1 - 0.18 11.9 29.5 1.4 9.0 15.4 3.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PIN_8 PF18476.1 GAM17554.1 - 0.47 10.3 17.3 0.16 11.8 7.7 2.6 2 0 0 2 2 2 0 PIN like domain GAS PF13851.6 GAM17554.1 - 5.2 6.4 31.3 0.045 13.1 6.7 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 GAM17554.1 - 5.5 7.4 31.1 0.038 14.4 4.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) BRCT PF00533.26 GAM17555.1 - 3.4e-34 117.1 14.0 1.4e-08 35.0 0.0 8.0 8 0 0 8 8 8 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAM17555.1 - 9.9e-29 99.1 1.8 3.3e-16 59.0 0.0 5.7 5 0 0 5 5 5 3 twin BRCT domain BRCT_2 PF16589.5 GAM17555.1 - 1.5e-25 89.4 9.3 6.9e-05 23.2 0.0 6.9 5 1 1 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 GAM17555.1 - 1e-10 41.8 6.3 0.067 13.5 0.1 6.9 7 0 0 7 7 7 3 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 GAM17555.1 - 4.7e-07 29.6 0.0 0.31 10.9 0.0 5.1 5 1 0 5 5 5 2 Regulator of Ty1 transposition protein 107 BRCT domain LRR_6 PF13516.6 GAM17556.1 - 3.7e-11 42.1 0.9 0.0006 19.7 0.3 3.3 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 GAM17556.1 - 0.041 14.3 1.2 0.041 14.3 1.2 3.2 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM17556.1 - 0.25 12.0 2.2 15 6.6 0.0 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat Thr_synth_N PF14821.6 GAM17558.1 - 4.4e-27 94.1 0.0 1.3e-26 92.6 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 GAM17558.1 - 2.9e-17 63.0 0.0 4.4e-16 59.1 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M60 PF13402.6 GAM17558.1 - 0.081 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like KLRAQ PF10205.9 GAM17559.1 - 2.8e-25 88.5 14.8 2.8e-25 88.5 14.8 5.1 3 2 1 4 4 4 1 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.9 GAM17559.1 - 2.5e-10 40.0 1.5 2.5e-10 40.0 1.5 3.1 2 1 0 2 2 2 1 Predicted coiled-coil domain-containing protein zinc_ribbon_5 PF13719.6 GAM17559.1 - 0.19 11.5 0.2 0.19 11.5 0.2 2.7 4 0 0 4 4 4 0 zinc-ribbon domain Tom37 PF10568.9 GAM17559.1 - 2 8.8 7.4 10 6.4 2.2 2.9 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein DUF1870 PF08965.10 GAM17559.1 - 9.6 6.3 19.3 1.7 8.7 0.6 4.5 3 3 1 5 5 5 0 Domain of unknown function (DUF1870) RabGAP-TBC PF00566.18 GAM17560.1 - 7.7e-39 133.6 10.9 9.6e-39 133.3 10.9 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CCDC50_N PF15295.6 GAM17560.1 - 0.0084 16.3 6.9 0.015 15.5 6.9 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus COesterase PF00135.28 GAM17560.1 - 0.14 11.0 1.4 0.16 10.8 1.4 1.0 1 0 0 1 1 1 0 Carboxylesterase family Cid2 PF09774.9 GAM17560.1 - 0.2 12.1 6.6 0.39 11.1 6.6 1.5 1 0 0 1 1 1 0 Caffeine-induced death protein 2 VIT1 PF01988.19 GAM17560.1 - 0.2 11.5 0.2 0.32 10.8 0.2 1.3 1 1 0 1 1 1 0 VIT family SSP160 PF06933.11 GAM17561.1 - 0.006 14.9 11.1 0.0093 14.2 11.1 1.4 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 GAM17561.1 - 0.98 7.3 5.8 1.4 6.8 5.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein V_ATPase_I PF01496.19 GAM17562.1 - 0.033 12.1 0.3 0.045 11.7 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4083 PF13314.6 GAM17562.1 - 0.062 13.2 0.0 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Connexin PF00029.19 GAM17562.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Connexin SARAF PF06682.12 GAM17562.1 - 0.11 12.2 0.1 0.2 11.2 0.1 1.5 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SID-1_RNA_chan PF13965.6 GAM17562.1 - 0.17 10.3 0.3 0.24 9.7 0.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TRIQK PF15168.6 GAM17562.1 - 0.2 11.6 1.6 0.43 10.5 1.6 1.6 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family Spore_YhaL PF14147.6 GAM17562.1 - 0.22 11.2 0.0 0.55 10.0 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein YhaL Presenilin PF01080.17 GAM17562.1 - 0.36 9.5 0.8 0.58 8.9 0.8 1.4 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 GAM17562.1 - 0.37 9.8 4.0 0.45 9.5 3.0 1.5 2 0 0 2 2 2 0 Solute carrier family 12 Zip PF02535.22 GAM17562.1 - 0.43 9.7 3.3 0.67 9.1 2.6 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 GAM17562.1 - 0.64 8.2 7.5 0.74 8.0 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4834 PF16118.5 GAM17562.1 - 1.9 9.5 7.1 22 6.1 7.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) TBCC_N PF16752.5 GAM17563.1 - 1.6e-12 47.9 11.9 1.6e-12 47.9 11.9 1.7 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain TBCC PF07986.12 GAM17563.1 - 5.9e-08 32.5 0.7 5.9e-08 32.5 0.7 1.8 2 0 0 2 2 2 1 Tubulin binding cofactor C USP19_linker PF16602.5 GAM17563.1 - 1.4 9.5 5.8 1.3 9.6 0.6 2.4 2 0 0 2 2 2 0 Linker region of USP19 deubiquitinase DUF4203 PF13886.6 GAM17564.1 - 7.6e-08 32.3 26.1 9.7e-08 31.9 26.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2628 PF10947.8 GAM17564.1 - 1.6 9.2 10.0 0.19 12.1 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Plasmodium_Vir PF05795.11 GAM17565.1 - 0.047 13.1 1.9 0.071 12.5 1.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RIFIN PF02009.16 GAM17565.1 - 0.24 11.2 4.8 0.38 10.6 4.8 1.3 1 0 0 1 1 1 0 Rifin Consortin_C PF15281.6 GAM17565.1 - 1.9 8.5 4.7 3.2 7.8 0.2 2.5 1 1 0 2 2 2 0 Consortin C-terminus NMD3 PF04981.13 GAM17566.1 - 3.1e-81 272.4 6.3 3.1e-81 272.4 6.3 1.5 2 0 0 2 2 2 1 NMD3 family Cwf_Cwc_15 PF04889.12 GAM17566.1 - 3.5 7.3 22.6 5.7 6.6 22.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CNDH2_C PF16858.5 GAM17567.1 - 4.2e-53 181.1 0.0 4.2e-53 181.1 0.0 3.3 3 1 1 4 4 4 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 GAM17567.1 - 4.2e-41 139.7 0.2 4.2e-41 139.7 0.2 4.1 3 1 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal AF-4 PF05110.13 GAM17567.1 - 0.00016 20.0 12.7 0.00016 20.0 12.7 2.1 2 0 0 2 2 2 1 AF-4 proto-oncoprotein GAGA_bind PF06217.12 GAM17567.1 - 0.18 12.1 11.4 0.14 12.4 5.2 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family DUF4692 PF15763.5 GAM17567.1 - 0.25 11.8 6.3 2.1e+02 2.3 12.5 2.5 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Rootletin PF15035.6 GAM17568.1 - 0.00093 19.3 2.3 0.0011 19.0 2.3 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 GAM17568.1 - 0.0011 19.1 7.3 0.0015 18.7 7.3 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Muted PF14942.6 GAM17568.1 - 0.0015 18.9 3.3 0.0025 18.2 3.3 1.3 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein Golgin_A5 PF09787.9 GAM17568.1 - 0.0022 17.5 2.4 0.0022 17.5 2.4 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 MobL PF18555.1 GAM17568.1 - 0.0057 15.9 1.6 0.006 15.9 1.6 1.0 1 0 0 1 1 1 1 MobL relaxases FAP206 PF12018.8 GAM17568.1 - 0.033 13.7 4.0 0.044 13.3 3.9 1.3 1 1 0 1 1 1 0 Domain of unknown function GIT_CC PF16559.5 GAM17568.1 - 0.047 13.6 6.8 0.13 12.2 4.0 2.6 1 1 2 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ABC_tran_CTD PF16326.5 GAM17568.1 - 0.11 12.7 3.8 0.14 12.5 3.0 1.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain FapA PF03961.13 GAM17568.1 - 0.14 10.7 3.3 0.15 10.7 3.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 GAM17568.1 - 0.35 10.2 3.9 0.47 9.8 3.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 GAM17568.1 - 0.47 10.8 8.3 1 9.7 1.3 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain bZIP_1 PF00170.21 GAM17568.1 - 0.74 9.9 6.5 1.4 9.1 2.8 2.2 1 1 1 2 2 2 0 bZIP transcription factor DivIC PF04977.15 GAM17568.1 - 2.4 8.0 6.6 3.8 7.4 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator FNIP PF05725.12 GAM17569.1 - 3.9e-64 212.6 19.0 2.4e-12 46.8 0.5 6.4 4 1 2 6 6 6 6 FNIP Repeat LRR_5 PF13306.6 GAM17569.1 - 2e-08 34.3 0.0 0.0013 18.7 0.0 2.7 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Glyco_hydro_108 PF05838.12 GAM17569.1 - 0.21 12.1 0.0 69 4.0 0.0 3.4 2 1 2 4 4 4 0 Glycosyl hydrolase 108 WD40 PF00400.32 GAM17570.1 - 2e-14 53.7 7.6 6.8e-05 23.6 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17570.1 - 2.6e-11 43.6 0.1 0.16 12.2 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAM17570.1 - 0.038 12.5 0.7 3.4 6.1 0.1 3.0 2 1 2 4 4 4 0 Cytochrome D1 heme domain Spt20 PF12090.8 GAM17570.1 - 0.15 11.6 13.0 0.24 11.0 13.0 1.3 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 GAM17570.1 - 0.76 8.6 16.6 1.3 7.9 16.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) WD40 PF00400.32 GAM17571.1 - 5.8e-10 39.6 3.8 0.00087 20.1 0.3 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17571.1 - 8.5e-05 22.8 0.1 0.18 12.1 0.1 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAM17571.1 - 0.17 12.4 0.1 1.7 9.2 0.1 2.5 2 0 0 2 2 2 0 PQQ-like domain DUF2828 PF11443.8 GAM17571.1 - 0.35 8.9 6.1 1 7.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 GAM17571.1 - 1.3 7.9 5.4 2.5 7.0 5.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GAM17571.1 - 3.5 6.3 7.1 5.7 5.6 7.1 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 GAM17571.1 - 4.2 5.4 7.8 5.9 4.9 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4746 PF15928.5 GAM17572.1 - 0.25 10.7 11.1 0.32 10.4 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF913 PF06025.12 GAM17572.1 - 0.59 9.1 5.4 0.75 8.7 5.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 GAM17572.1 - 0.75 9.2 25.7 0.89 8.9 25.7 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 GAM17572.1 - 1 8.7 26.3 1.3 8.3 26.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Hid1 PF12722.7 GAM17572.1 - 1.1 7.3 7.4 1.3 7.1 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Utp14 PF04615.13 GAM17572.1 - 1.1 7.7 19.6 1.3 7.5 19.6 1.0 1 0 0 1 1 1 0 Utp14 protein MDM31_MDM32 PF08118.11 GAM17572.1 - 1.8 7.1 5.1 2.6 6.6 5.1 1.2 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Nop14 PF04147.12 GAM17572.1 - 1.8 6.6 27.5 2.2 6.4 27.5 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GAM17572.1 - 2.1 7.1 7.7 2.5 6.8 7.7 1.1 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 GAM17572.1 - 3 8.0 7.8 4.3 7.5 7.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal BUD22 PF09073.10 GAM17572.1 - 3.3 6.9 22.6 4.3 6.6 22.6 1.2 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.25 GAM17573.1 - 4e-18 65.7 0.1 8.1e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17573.1 - 2e-11 43.7 0.1 1e-10 41.4 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase TIG PF01833.24 GAM17575.1 - 7.4e-20 70.8 58.1 1.4e-09 37.9 2.7 8.1 6 2 0 6 6 6 5 IPT/TIG domain EGF PF00008.27 GAM17575.1 - 0.0012 19.1 6.7 0.0032 17.7 6.7 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 GAM17575.1 - 0.37 11.2 11.6 0.94 9.9 11.6 1.7 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 GAM17575.1 - 1.1 9.5 6.9 3.5 7.8 6.9 1.8 1 0 0 1 1 1 0 Laminin EGF domain EGF_alliinase PF04863.13 GAM17575.1 - 1.6 9.2 6.5 1.3 9.5 4.1 2.1 2 0 0 2 2 2 0 Alliinase EGF-like domain EGF_Tenascin PF18720.1 GAM17575.1 - 8.1 6.6 8.8 24 5.1 8.8 1.9 1 0 0 1 1 1 0 Tenascin EGF domain Peptidase_C1 PF00112.23 GAM17576.1 - 4.8e-75 252.4 5.9 4.8e-75 252.4 5.9 1.9 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM17576.1 - 5.2e-15 55.6 9.4 1.2e-14 54.5 9.4 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF155 PF02582.14 GAM17577.1 - 0.095 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 His_Phos_2 PF00328.22 GAM17578.1 - 8.6e-18 64.8 2.5 2.3e-16 60.1 2.5 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Spy1 PF11357.8 GAM17578.1 - 0.014 15.7 0.2 0.026 14.8 0.2 1.4 1 0 0 1 1 1 0 Cell cycle regulatory protein SUIM_assoc PF16619.5 GAM17578.1 - 7.6 6.7 9.4 19 5.4 9.4 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ion_trans PF00520.31 GAM17579.1 - 5.2e-06 25.9 9.6 7.2e-06 25.4 9.6 1.1 1 0 0 1 1 1 1 Ion transport protein DUF588 PF04535.12 GAM17579.1 - 1.1 9.1 5.2 0.31 10.8 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF588) Hum_adeno_E3A PF05393.11 GAM17579.1 - 7.5 6.6 8.2 4.5 7.3 3.0 2.7 1 1 1 3 3 3 0 Human adenovirus early E3A glycoprotein Rhomboid PF01694.22 GAM17580.1 - 3.6e-22 79.0 10.0 6.1e-22 78.2 10.0 1.3 1 0 0 1 1 1 1 Rhomboid family MORN PF02493.20 GAM17580.1 - 0.002 17.9 2.7 0.031 14.1 0.4 2.9 2 0 0 2 2 2 1 MORN repeat SR-25 PF10500.9 GAM17580.1 - 0.037 13.6 4.2 0.05 13.2 4.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4366 PF14283.6 GAM17580.1 - 0.049 13.7 0.1 0.13 12.3 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 GAM17580.1 - 0.63 8.7 3.5 0.41 9.3 1.2 1.8 2 0 0 2 2 2 0 Presenilin Piezo_RRas_bdg PF12166.8 GAM17580.1 - 2.8 7.1 10.0 4.6 6.4 8.8 1.8 1 1 1 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain Avl9 PF09794.9 GAM17581.1 - 1.2e-56 192.0 3.3 2.3e-56 191.2 3.3 1.5 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 GAM17581.1 - 9.1e-05 22.4 0.7 0.059 13.3 0.1 2.9 2 1 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 GAM17581.1 - 0.00025 20.7 1.0 0.00051 19.7 1.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 GAM17581.1 - 0.019 14.9 0.3 0.06 13.3 0.3 1.9 1 0 0 1 1 1 0 DENN (AEX-3) domain Swi5 PF07061.11 GAM17581.1 - 0.11 12.6 0.5 2.2 8.4 0.2 2.6 2 0 0 2 2 2 0 Swi5 Pribosyltran PF00156.27 GAM17582.1 - 5.2e-19 68.3 0.0 5.9e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAM17582.1 - 0.085 12.3 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Dus PF01207.17 GAM17583.1 - 4.2e-51 173.9 0.0 5.3e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Aldolase_II PF00596.21 GAM17584.1 - 8.5e-44 149.7 0.0 1.1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FtsX PF02687.21 GAM17585.1 - 8.3 7.0 8.6 1.5e+02 3.0 8.7 2.0 1 1 1 2 2 2 0 FtsX-like permease family FAA_hydrolase PF01557.18 GAM17586.1 - 5.3e-56 189.7 0.0 7.2e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GAM17586.1 - 1.1e-31 109.2 0.0 2.1e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal bZIP_2 PF07716.15 GAM17587.1 - 4e-08 33.2 8.4 4e-08 33.2 8.4 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAM17587.1 - 6.3e-06 26.2 4.4 6.3e-06 26.2 4.4 2.1 2 0 0 2 2 2 1 bZIP transcription factor TSC22 PF01166.18 GAM17587.1 - 0.055 13.8 0.3 0.055 13.8 0.3 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family v110 PF01639.17 GAM17588.1 - 0.028 14.3 0.4 0.14 12.1 0.2 2.3 1 1 1 2 2 2 0 Viral family 110 Mad3_BUB1_I_2 PF17014.5 GAM17588.1 - 8.6 6.5 12.2 1.7 8.8 0.1 3.9 3 1 1 4 4 4 0 Putative Mad3/BUB1 like region 1 protein Vps23_core PF09454.10 GAM17589.1 - 1.7e-26 91.9 0.3 3.2e-26 91.0 0.3 1.5 1 0 0 1 1 1 1 Vps23 core domain UEV PF05743.13 GAM17589.1 - 7.2e-24 84.0 0.1 1.4e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.26 GAM17589.1 - 0.0057 16.3 0.7 0.015 14.9 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Clathrin_lg_ch PF01086.17 GAM17589.1 - 0.0081 16.2 0.4 0.015 15.4 0.4 1.3 1 0 0 1 1 1 1 Clathrin light chain APG6_N PF17675.1 GAM17589.1 - 0.04 14.5 12.1 0.29 11.7 12.1 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region Prok-E2_B PF14461.6 GAM17589.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF5327 PF17261.2 GAM17589.1 - 2.5 8.9 6.5 0.67 10.7 2.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5327) ATG16 PF08614.11 GAM17589.1 - 6.3 7.0 20.7 0.76 10.0 6.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AbiH PF14253.6 GAM17589.1 - 6.6 6.5 8.6 8.6 6.1 7.4 1.8 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH Choline_transpo PF04515.12 GAM17590.1 - 1.1e-56 192.4 44.8 2.2e-56 191.5 36.8 2.3 2 0 0 2 2 2 2 Plasma-membrane choline transporter WASH_WAHD PF11945.8 GAM17591.1 - 3.9e-54 184.2 0.1 5.1e-54 183.8 0.1 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex WH2 PF02205.20 GAM17591.1 - 6.3e-06 25.9 0.2 1.5e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 WH2 motif Baculo_PEP_C PF04513.12 GAM17591.1 - 0.17 11.9 0.5 0.35 10.9 0.1 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cpn60_TCP1 PF00118.24 GAM17592.1 - 1.5e-151 505.4 14.5 1.7e-151 505.2 14.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2 PF00152.20 GAM17593.1 - 5.6e-93 311.4 0.0 7.7e-93 311.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.15 GAM17593.1 - 6.1e-41 140.1 0.0 1.1e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.25 GAM17593.1 - 4e-13 49.2 0.0 7.6e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 GAM17593.1 - 0.016 15.4 0.0 0.045 14.0 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF3656 PF12392.8 GAM17593.1 - 0.05 14.3 0.2 0.44 11.2 0.0 2.5 2 1 1 3 3 3 0 Collagenase tRNA_synt_1c_R2 PF04557.15 GAM17593.1 - 0.074 14.0 4.7 0.15 13.0 4.7 1.5 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 COMM_domain PF07258.14 GAM17594.1 - 7.3e-17 61.3 0.3 2e-16 59.9 0.1 1.9 2 0 0 2 2 2 1 COMM domain SAP PF02037.27 GAM17595.1 - 1.3e-06 28.0 0.0 3.7e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 SAP domain Lipin_N PF04571.14 GAM17595.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 lipin, N-terminal conserved region DUF1645 PF07816.11 GAM17595.1 - 0.13 12.8 1.0 17 6.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) FNIP PF05725.12 GAM17596.1 - 8.3e-11 41.9 7.4 2.4e-06 27.6 0.1 5.8 4 2 1 5 5 5 3 FNIP Repeat F-box-like PF12937.7 GAM17596.1 - 0.067 13.1 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 F-box-like RVT_1 PF00078.27 GAM17600.1 - 7.5e-16 58.3 0.0 1.5e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SQHop_cyclase_C PF13243.6 GAM17601.1 - 9.2e-64 215.5 0.0 3.2e-57 194.0 0.0 2.6 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAM17601.1 - 2.3e-47 161.5 0.0 4.1e-41 141.0 0.0 4.1 3 1 1 4 4 4 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 GAM17601.1 - 8.6e-41 137.4 4.0 7.3e-10 38.4 0.4 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 GAM17601.1 - 4.9e-05 22.8 0.3 0.2 10.9 0.0 4.0 3 2 1 4 4 4 2 Pectic acid lyase TED_complement PF07678.14 GAM17601.1 - 9.9e-05 21.5 1.1 5.9 5.8 0.0 4.6 4 2 1 5 5 5 3 A-macroglobulin TED domain ABC2_membrane PF01061.24 GAM17602.1 - 5.2e-34 117.5 25.9 5.2e-34 117.5 25.9 1.5 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAM17602.1 - 1.8e-27 96.5 0.0 4.7e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM17602.1 - 4.5e-08 33.3 0.2 0.0088 15.9 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAM17602.1 - 0.00088 19.7 0.0 0.0023 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 GAM17602.1 - 0.001 18.5 0.0 0.41 10.1 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 GAM17602.1 - 0.0013 17.9 0.2 0.0023 17.0 0.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 GAM17602.1 - 0.0016 18.7 0.0 0.0076 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAM17602.1 - 0.0026 17.7 0.1 0.0072 16.2 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 GAM17602.1 - 0.0036 17.0 0.1 0.0087 15.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 GAM17602.1 - 0.015 15.9 0.0 0.026 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAM17602.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 GAM17602.1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 GAM17602.1 - 0.018 14.5 0.0 0.29 10.5 0.0 2.4 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_23 PF13476.6 GAM17602.1 - 0.026 15.0 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAM17602.1 - 0.027 14.7 0.1 0.046 14.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM17602.1 - 0.031 14.4 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAM17602.1 - 0.044 14.2 0.0 0.75 10.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 GAM17602.1 - 0.059 13.0 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 GAM17602.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SbcCD_C PF13558.6 GAM17602.1 - 0.1 12.8 0.8 1.9 8.8 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 GAM17602.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAM17602.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF4516 PF14990.6 GAM17602.1 - 0.21 11.3 1.3 15 5.4 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) vWA-TerF-like PF10138.9 GAM17603.1 - 4.3e-10 40.0 0.0 5.7e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.6 GAM17603.1 - 1.1e-06 29.3 0.0 1.7e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAM17603.1 - 1.5e-06 28.6 0.1 1.9e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAM17603.1 - 3.2e-05 23.9 0.0 4.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 GAM17603.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein ATP-sulfurylase PF01747.17 GAM17604.1 - 1.7e-82 276.0 0.0 2.2e-82 275.6 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 GAM17604.1 - 6.8e-60 201.5 0.0 1.4e-59 200.6 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 GAM17604.1 - 4.1e-48 163.1 0.0 5.9e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain AAA_29 PF13555.6 GAM17604.1 - 6.6e-05 22.6 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 GAM17604.1 - 0.0019 18.4 0.0 0.004 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM17604.1 - 0.0026 18.3 0.0 0.005 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAM17604.1 - 0.0037 16.8 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 GAM17604.1 - 0.0078 16.6 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 GAM17604.1 - 0.0086 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 GAM17604.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 GAM17604.1 - 0.016 15.8 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 GAM17604.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Sigma54_activat PF00158.26 GAM17604.1 - 0.053 13.2 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 GAM17604.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAM17604.1 - 0.081 13.4 0.2 0.13 12.8 0.2 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAM17604.1 - 0.096 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CPT PF07931.12 GAM17604.1 - 0.12 12.2 0.1 3 7.6 0.1 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MeaB PF03308.16 GAM17604.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 GAM17604.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 GAM17604.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Cytidylate_kin PF02224.18 GAM17604.1 - 0.21 11.3 0.0 8.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase PTEN_C2 PF10409.9 GAM17605.1 - 3.8e-18 65.6 2.7 5.3e-17 61.8 2.7 2.2 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 GAM17605.1 - 1.6e-06 28.0 0.7 4.1e-06 26.6 0.0 2.0 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAM17605.1 - 3.9e-06 27.1 0.3 1.3e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 GAM17605.1 - 9.6e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAM17605.1 - 0.00014 21.5 0.4 0.00047 19.8 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 GAM17605.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 GAM17605.1 - 0.038 13.6 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPn PF14671.6 GAM17605.1 - 0.06 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half TFIIE_alpha PF02002.17 GAM17606.1 - 2e-13 50.1 1.3 2e-13 50.1 1.3 2.0 2 0 0 2 2 2 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.10 GAM17606.1 - 0.015 15.4 0.6 0.037 14.1 0.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Stc1 PF12898.7 GAM17606.1 - 0.038 14.5 1.3 0.096 13.3 1.3 1.7 1 0 0 1 1 1 0 Stc1 domain Rrf2 PF02082.20 GAM17606.1 - 0.039 14.3 0.5 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator RXT2_N PF08595.11 GAM17606.1 - 1.1 9.3 9.4 0.065 13.3 3.7 1.9 3 0 0 3 3 3 0 RXT2-like, N-terminal zf-C2H2_6 PF13912.6 GAM17606.1 - 4.5 7.4 6.6 0.84 9.7 2.5 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger DDE_3 PF13358.6 GAM17607.1 - 3.8e-23 81.9 0.1 6.6e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease eIF-5_eIF-2B PF01873.17 GAM17607.1 - 0.029 14.2 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain found in IF2B/IF5 CNOT11 PF10155.9 GAM17607.1 - 0.099 12.8 0.6 0.79 9.9 0.0 2.4 2 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 MRNIP PF15749.5 GAM17608.1 - 3e-18 66.5 38.0 1.2e-15 58.2 38.0 4.0 1 1 0 1 1 1 1 MRN-interacting protein DUF4813 PF16072.5 GAM17608.1 - 0.022 14.4 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Abhydrolase_2 PF02230.16 GAM17609.1 - 2.4e-60 204.0 0.2 2.6e-60 203.9 0.2 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 GAM17609.1 - 2.1e-05 24.3 0.0 4.5e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 GAM17609.1 - 2.2e-05 24.1 0.2 0.00029 20.4 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAM17609.1 - 3.4e-05 23.6 0.5 0.00027 20.7 0.5 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM17609.1 - 0.00022 20.6 1.1 0.15 11.3 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM17609.1 - 0.00039 21.1 0.0 0.00058 20.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAM17609.1 - 0.019 14.5 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 GAM17609.1 - 0.025 14.5 0.0 0.21 11.4 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Cutinase PF01083.22 GAM17609.1 - 0.078 12.9 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Cutinase Esterase PF00756.20 GAM17609.1 - 0.09 12.4 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative esterase COesterase PF00135.28 GAM17610.1 - 1.4e-12 47.2 0.8 3e-12 46.2 0.1 1.8 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM17610.1 - 9.7e-11 41.9 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 GAM17610.1 - 5.3e-07 29.0 0.4 8e-07 28.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.7 GAM17610.1 - 1.5e-05 24.0 0.0 2.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 GAM17610.1 - 2.5e-05 23.7 0.0 0.00018 20.9 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM17610.1 - 0.00012 21.6 0.2 0.0002 20.9 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAM17610.1 - 0.004 16.8 0.0 0.047 13.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 GAM17610.1 - 0.006 16.3 0.3 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 GAM17610.1 - 0.006 16.2 0.3 0.006 16.2 0.3 1.5 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 GAM17610.1 - 0.0091 16.6 0.0 0.013 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 GAM17610.1 - 0.013 14.8 0.2 0.029 13.7 0.2 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 GAM17610.1 - 0.038 14.1 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Tubulin PF00091.25 GAM17611.1 - 7.2e-68 228.7 0.0 1.1e-67 228.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAM17611.1 - 3.1e-43 146.9 0.4 4.8e-43 146.3 0.4 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAM17611.1 - 2.8e-05 23.9 0.0 0.00028 20.6 0.0 2.4 2 1 1 3 3 3 1 Tubulin domain Tubulin_2 PF13809.6 GAM17611.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like PGM_PMM_II PF02879.16 GAM17611.1 - 0.13 12.8 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Rotamase PF00639.21 GAM17612.1 - 2.5e-24 86.1 0.0 4.9e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAM17612.1 - 4.5e-21 75.6 0.0 6.8e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain FHA PF00498.26 GAM17612.1 - 1.4e-19 70.2 0.4 9.8e-19 67.5 0.0 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 GAM17612.1 - 4.7e-08 33.3 0.1 2.7e-07 30.8 0.0 2.2 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain Rotamase_2 PF13145.6 GAM17612.1 - 0.0023 18.7 0.0 0.0042 17.9 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Sec5 PF15469.6 GAM17613.1 - 1.6e-43 148.7 4.7 2.2e-43 148.3 0.5 2.6 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 GAM17613.1 - 0.00027 21.0 0.1 0.00085 19.4 0.1 1.9 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 GAM17613.1 - 0.023 14.8 1.8 0.15 12.2 0.0 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 GAM17613.1 - 1.7 9.1 5.2 12 6.3 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF3510) FHA PF00498.26 GAM17614.1 - 3.6e-21 75.3 0.0 8.9e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAM17614.1 - 7.1e-10 39.1 0.1 2.5e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FUSC PF04632.12 GAM17614.1 - 2.4 6.6 7.7 4.6 5.7 7.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DPBB_1 PF03330.18 GAM17615.1 - 0.005 17.1 0.9 0.18 12.1 1.0 2.6 2 1 0 2 2 2 1 Lytic transglycolase SET PF00856.28 GAM17617.1 - 1.8e-14 54.5 6.2 1.9e-13 51.1 6.2 2.2 1 1 0 1 1 1 1 SET domain RP-C_C PF11800.8 GAM17617.1 - 0.57 10.2 2.8 0.94 9.5 2.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Hid1 PF12722.7 GAM17617.1 - 1.2 7.1 5.9 1.7 6.7 5.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPP4R2 PF09184.11 GAM17617.1 - 1.3 8.6 14.5 2 7.9 14.5 1.3 1 0 0 1 1 1 0 PPP4R2 Mpp10 PF04006.12 GAM17617.1 - 1.3 7.3 16.4 1.8 6.9 16.4 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 GAM17617.1 - 1.5 8.2 15.8 2.2 7.6 15.8 1.1 1 0 0 1 1 1 0 SDA1 DUF4746 PF15928.5 GAM17617.1 - 6.1 6.2 12.2 10 5.4 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 GAM17617.1 - 8.5 5.0 6.8 12 4.5 6.8 1.2 1 0 0 1 1 1 0 Presenilin HTH_Tnp_Tc5 PF03221.16 GAM17618.1 - 3.6e-10 39.7 0.1 5.9e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain COG4 PF08318.12 GAM17619.1 - 9.1e-10 38.1 0.6 9.1e-10 38.1 0.6 1.9 2 0 0 2 2 2 1 COG4 transport protein Sec10 PF07393.11 GAM17619.1 - 6.7e-09 34.7 3.0 1.1e-08 34.0 3.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec10 RINT1_TIP1 PF04437.13 GAM17619.1 - 6.7e-05 22.0 2.1 6.7e-05 22.0 2.1 1.5 1 1 0 1 1 1 1 RINT-1 / TIP-1 family DIL PF01843.19 GAM17619.1 - 0.0018 18.5 1.1 0.0062 16.8 1.1 1.9 1 0 0 1 1 1 1 DIL domain Sec15 PF04091.12 GAM17619.1 - 0.0045 16.5 6.5 0.0099 15.3 6.5 1.5 1 1 0 1 1 1 1 Exocyst complex subunit Sec15-like DNA_pol3_delt_C PF14840.6 GAM17619.1 - 0.37 11.1 3.2 0.58 10.5 0.5 2.5 2 1 1 3 3 3 0 Processivity clamp loader gamma complex DNA pol III C-term Prp18 PF02840.15 GAM17620.1 - 3.1 7.8 21.4 0.069 13.2 4.7 4.3 2 2 3 5 5 5 0 Prp18 domain PHO4 PF01384.20 GAM17621.1 - 2.7e-103 345.6 16.7 3.1e-103 345.4 16.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 GAM17621.1 - 0.19 12.0 7.1 5.8 7.3 0.2 2.9 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Bact_lectin PF18483.1 GAM17622.1 - 1.4e-19 70.9 0.0 2.2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 GAM17622.1 - 9e-16 58.2 0.0 1.5e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Legume lectin domain C9orf72-like PF15019.6 GAM17623.1 - 3.5e-39 134.8 3.1 3.5e-39 134.8 3.1 1.9 2 0 0 2 2 2 1 C9orf72-like protein family HSP20 PF00011.21 GAM17624.1 - 2.2e-23 82.3 1.0 2.9e-23 82.0 1.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM17624.1 - 2.1e-10 40.0 0.0 2.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4097 PF13349.6 GAM17624.1 - 0.0045 16.4 1.6 0.0051 16.2 1.6 1.1 1 0 0 1 1 1 1 Putative adhesin CS PF04969.16 GAM17624.1 - 0.013 16.5 1.2 0.026 15.5 1.2 1.6 1 1 0 1 1 1 0 CS domain PA14 PF07691.12 GAM17624.1 - 0.083 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 PA14 domain AAA_2 PF07724.14 GAM17625.1 - 1e-49 168.9 0.0 2.3e-48 164.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAM17625.1 - 2.7e-34 117.2 1.5 2.7e-34 117.2 1.5 2.2 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 GAM17625.1 - 1e-26 92.8 0.4 1e-26 92.8 0.4 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 GAM17625.1 - 2.8e-23 82.8 0.0 9.8e-13 48.7 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM17625.1 - 1.9e-15 57.1 0.0 1.4e-09 38.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM17625.1 - 8.1e-10 39.3 6.0 3.2e-05 24.4 0.2 4.6 4 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 GAM17625.1 - 5.4e-08 33.2 6.1 0.024 14.9 0.0 5.2 3 2 1 4 4 3 2 AAA domain Sigma54_activat PF00158.26 GAM17625.1 - 4.3e-07 29.8 0.0 0.00029 20.6 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 GAM17625.1 - 3.7e-06 26.5 0.0 0.015 14.7 0.0 3.7 2 1 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 GAM17625.1 - 6.1e-06 25.8 0.0 0.22 10.9 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAM17625.1 - 1.7e-05 24.4 0.0 0.077 12.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 GAM17625.1 - 2.5e-05 24.9 6.6 0.19 12.2 6.9 3.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 GAM17625.1 - 3.3e-05 23.9 0.0 0.041 13.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAM17625.1 - 4.7e-05 23.2 0.0 0.11 12.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 GAM17625.1 - 0.00019 21.8 0.1 2.7 8.4 0.0 3.9 4 0 0 4 4 3 2 RNA helicase RuvB_N PF05496.12 GAM17625.1 - 0.00022 21.0 2.0 0.47 10.2 0.0 3.7 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 GAM17625.1 - 0.00035 20.8 0.0 1.7 8.9 0.0 3.0 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 GAM17625.1 - 0.00041 20.3 6.5 3 7.7 0.1 4.6 4 1 1 5 5 4 2 ATPase domain predominantly from Archaea TsaE PF02367.17 GAM17625.1 - 0.00071 19.6 0.0 1.9 8.5 0.0 2.8 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GAM17625.1 - 0.00084 19.1 0.0 0.71 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAM17625.1 - 0.0014 18.5 1.9 2.5 8.0 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase NACHT PF05729.12 GAM17625.1 - 0.0041 17.1 0.0 0.32 10.9 0.0 3.0 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 GAM17625.1 - 0.0082 16.7 3.6 3.5 8.2 0.1 3.4 3 2 0 3 3 2 2 AAA domain AAA_19 PF13245.6 GAM17625.1 - 0.0086 16.4 0.0 1.8 8.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 GAM17625.1 - 0.011 16.3 0.7 7.3 7.1 0.0 3.4 3 0 0 3 3 3 0 ABC transporter DUF815 PF05673.13 GAM17625.1 - 0.012 14.8 0.2 1.1 8.3 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 GAM17625.1 - 0.013 15.3 0.0 0.53 10.0 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 GAM17625.1 - 0.018 15.2 0.0 13 6.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain ResIII PF04851.15 GAM17625.1 - 0.028 14.4 0.1 15 5.6 0.0 3.7 3 1 0 4 4 4 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 GAM17625.1 - 0.028 14.6 0.0 5.2 7.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAM17625.1 - 0.032 13.9 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 GAM17625.1 - 0.041 13.5 0.0 4.8 6.8 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_3 PF07726.11 GAM17625.1 - 0.046 13.6 0.0 25 4.7 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SpoIIE PF07228.12 GAM17626.1 - 4.2e-11 43.1 0.0 9.1e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAM17626.1 - 0.00012 21.8 1.1 0.00034 20.3 0.0 2.3 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.21 GAM17626.1 - 0.00075 19.2 6.1 0.18 11.4 0.0 3.2 3 0 0 3 3 3 2 Protein phosphatase 2C GET2 PF08690.10 GAM17626.1 - 0.0028 17.4 4.3 0.0028 17.4 4.3 4.2 4 0 0 4 4 4 1 GET complex subunit GET2 PPR_3 PF13812.6 GAM17626.1 - 0.046 13.8 0.1 0.94 9.6 0.0 2.6 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DUF4217 PF13959.6 GAM17626.1 - 0.31 11.3 2.1 3.9 7.8 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) DUF3446 PF11928.8 GAM17626.1 - 7 7.0 29.3 2 8.8 6.4 3.6 3 0 0 3 3 3 0 Early growth response N-terminal domain Dna2 PF08696.11 GAM17628.1 - 1.9e-55 187.8 1.2 8.3e-55 185.7 0.4 2.4 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 GAM17628.1 - 9.4e-52 175.5 0.0 2.3e-51 174.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM17628.1 - 2.5e-26 93.0 15.3 4e-17 62.9 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 GAM17628.1 - 5e-13 49.2 0.0 9.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM17628.1 - 2.1e-09 37.8 0.0 4.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAM17628.1 - 4e-06 26.7 0.3 0.12 12.1 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 GAM17628.1 - 0.0017 18.2 0.0 0.0085 16.0 0.0 2.3 1 0 0 1 1 1 1 Helicase Cas_Cas4 PF01930.17 GAM17628.1 - 0.011 15.9 0.9 0.21 11.7 0.5 3.0 2 1 0 2 2 2 0 Domain of unknown function DUF83 PIF1 PF05970.14 GAM17628.1 - 0.024 13.8 0.1 0.024 13.8 0.1 2.9 3 1 0 3 3 3 0 PIF1-like helicase Diphthamide_syn PF01866.17 GAM17628.1 - 0.073 12.5 0.0 0.34 10.3 0.0 2.1 2 0 0 2 2 2 0 Putative diphthamide synthesis protein UvrD_C_2 PF13538.6 GAM17628.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.21 GAM17628.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 GAM17628.1 - 0.16 12.3 0.0 0.56 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain MgsA_C PF12002.8 GAM17629.1 - 1.1e-55 188.1 0.1 3e-55 186.7 0.1 1.7 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 GAM17629.1 - 2.6e-24 85.4 0.3 6.6e-24 84.1 0.3 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 GAM17629.1 - 2.4e-17 63.6 0.0 4.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAM17629.1 - 2e-13 50.4 0.0 6.7e-13 48.7 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAM17629.1 - 2.1e-07 31.0 0.1 2.5e-06 27.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAM17629.1 - 6.8e-06 26.1 0.0 1.7e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAM17629.1 - 1e-05 25.3 0.0 0.00062 19.5 0.0 2.3 1 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 GAM17629.1 - 1.6e-05 25.3 0.1 0.013 15.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta2 PF13177.6 GAM17629.1 - 1.8e-05 24.6 0.3 4.2e-05 23.4 0.3 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 GAM17629.1 - 6.6e-05 22.4 0.1 0.17 11.2 0.0 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAM17629.1 - 6.7e-05 23.4 0.0 0.00018 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GAM17629.1 - 0.00042 20.5 0.0 0.0013 18.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_8 PF12780.7 GAM17629.1 - 0.0006 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_33 PF13671.6 GAM17629.1 - 0.0018 18.5 0.0 0.0053 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM17629.1 - 0.0021 18.3 0.3 0.044 14.0 0.4 2.4 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.22 GAM17629.1 - 0.0027 16.9 0.0 0.0099 15.1 0.0 1.9 1 1 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.6 GAM17629.1 - 0.0077 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 GAM17629.1 - 0.011 15.9 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain zf-Di19 PF05605.12 GAM17629.1 - 0.012 15.9 0.7 0.032 14.5 0.7 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding TIP49 PF06068.13 GAM17629.1 - 0.02 14.1 0.0 0.056 12.6 0.0 1.7 1 1 1 2 2 2 0 TIP49 P-loop domain DUF815 PF05673.13 GAM17629.1 - 0.041 13.0 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 GAM17629.1 - 0.048 13.6 0.1 0.99 9.3 0.0 2.4 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 GAM17629.1 - 0.079 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAM17629.1 - 0.091 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 GAM17629.1 - 0.091 12.5 0.0 0.091 12.5 0.0 2.5 2 1 1 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 GAM17629.1 - 0.098 13.0 0.6 17 5.8 0.1 3.1 2 1 1 3 3 3 0 AAA domain IstB_IS21 PF01695.17 GAM17629.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 GAM17629.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.9 GAM17629.1 - 0.87 8.1 13.8 1.2 7.6 13.8 1.1 1 0 0 1 1 1 0 Macoilin family PRELI PF04707.14 GAM17630.1 - 1.5e-47 161.4 0.0 2.1e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family baeRF_family5 PF18846.1 GAM17630.1 - 0.042 14.0 0.2 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 RT_RNaseH_2 PF17919.1 GAM17631.1 - 8.5e-13 48.2 0.0 1.6e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAM17631.1 - 0.0039 17.4 0.0 0.2 11.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase GLTP PF08718.11 GAM17631.1 - 0.078 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) HD_3 PF13023.6 GAM17632.1 - 4.1e-44 150.4 0.0 4.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 GAM17632.1 - 5.3e-13 49.1 0.0 6.3e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 GAM17632.1 - 6.9e-06 26.3 0.0 1.6e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 HD domain RE_R_Pab1 PF09522.10 GAM17632.1 - 0.12 12.4 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 R.Pab1 restriction endonuclease Myb_DNA-binding PF00249.31 GAM17633.1 - 2.8e-10 40.2 0.0 1.6e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 GAM17633.1 - 1.6e-08 34.2 5.9 3.1e-08 33.3 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 GAM17633.1 - 7.4e-08 32.6 0.9 1.7e-07 31.5 0.1 2.0 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 GAM17633.1 - 0.0025 18.0 0.0 0.0074 16.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_1 PF00130.22 GAM17633.1 - 0.13 12.2 0.7 0.25 11.3 0.7 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Siva PF05458.12 GAM17633.1 - 4.6 6.9 6.5 29 4.3 2.7 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) SusD_RagB PF07980.11 GAM17634.1 - 0.046 13.3 0.9 0.054 13.1 0.9 1.0 1 0 0 1 1 1 0 SusD family Mucin PF01456.17 GAM17635.1 - 0.00095 19.2 36.5 0.00095 19.2 36.5 3.4 1 1 1 2 2 2 1 Mucin-like glycoprotein Hemerythrin PF01814.23 GAM17636.1 - 5.5e-10 40.0 2.1 2.2e-08 34.8 3.0 2.1 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain WD40 PF00400.32 GAM17637.1 - 1.2e-40 136.7 19.1 4.7e-10 39.9 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17637.1 - 2.6e-14 53.3 0.2 0.0012 19.1 0.0 5.4 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM17637.1 - 1.7e-09 37.5 0.1 0.0077 15.6 0.0 4.0 2 2 2 4 4 4 3 WD40-like domain Nup160 PF11715.8 GAM17637.1 - 1.2e-08 34.1 0.2 0.12 11.0 0.0 3.7 2 2 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 GAM17637.1 - 4e-07 30.1 0.8 0.0072 16.2 0.0 3.0 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM17637.1 - 5e-05 22.4 0.2 0.87 8.5 0.0 3.6 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 GAM17637.1 - 0.00089 18.9 0.1 0.017 14.7 0.1 2.5 1 1 1 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 GAM17637.1 - 0.0041 17.6 8.4 3.8 8.1 0.1 4.9 5 1 0 5 5 4 2 PQQ-like domain PALB2_WD40 PF16756.5 GAM17637.1 - 0.012 14.6 0.5 0.82 8.5 0.2 2.6 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PKD PF00801.20 GAM17637.1 - 0.028 14.2 4.8 0.47 10.3 0.6 3.9 3 1 0 3 3 3 0 PKD domain Mfa1 PF17445.2 GAM17637.1 - 4.5 7.4 6.0 9.3 6.4 6.0 1.6 1 0 0 1 1 1 0 Mating factor A1 Kelch_6 PF13964.6 GAM17638.1 - 1.8e-14 53.4 5.7 1.1e-06 28.6 0.1 4.8 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM17638.1 - 1.2e-13 50.8 0.5 3.8e-07 30.0 0.1 3.9 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM17638.1 - 6.2e-07 29.2 0.2 1.2 9.3 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 GAM17638.1 - 2e-06 27.3 0.2 0.013 15.1 0.0 4.0 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 GAM17638.1 - 9.6e-05 22.6 1.9 0.0039 17.4 0.0 3.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM17638.1 - 0.23 11.5 4.7 2.6 8.1 0.3 2.5 2 0 0 2 2 2 0 Kelch motif zf-B_box PF00643.24 GAM17638.1 - 0.76 10.0 3.7 1.8 8.7 0.8 2.3 2 0 0 2 2 2 0 B-box zinc finger Kelch_6 PF13964.6 GAM17639.1 - 5.7e-18 64.5 4.5 7.2e-05 22.9 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAM17639.1 - 2.7e-11 42.9 7.4 0.0036 16.8 0.0 5.3 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM17639.1 - 9.8e-11 41.5 2.5 0.065 13.2 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain zf-B_box PF00643.24 GAM17639.1 - 7.3e-09 35.6 4.3 1.9e-08 34.3 4.3 1.7 1 0 0 1 1 1 1 B-box zinc finger Kelch_5 PF13854.6 GAM17639.1 - 7.1e-07 29.1 0.9 0.26 11.3 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 GAM17639.1 - 2e-05 24.3 6.9 1.5 8.9 0.2 4.8 4 1 1 5 5 5 3 Kelch motif Fibin PF15819.5 GAM17639.1 - 0.00013 21.8 0.1 0.00027 20.7 0.1 1.5 1 0 0 1 1 1 1 Fin bud initiation factor homologue zf-UBR PF02207.20 GAM17639.1 - 0.011 15.9 2.4 0.037 14.2 2.4 1.9 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF5364 PF17322.2 GAM17639.1 - 0.032 14.6 0.5 0.07 13.4 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5364) Kelch_3 PF13415.6 GAM17639.1 - 0.063 13.6 5.1 10 6.6 0.0 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain CRAL_TRIO PF00650.20 GAM17640.1 - 1.4e-35 122.3 0.1 2.1e-35 121.8 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM17640.1 - 2.5e-07 30.7 0.5 6.6e-07 29.4 0.5 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAM17640.1 - 0.00026 21.1 0.0 0.0004 20.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain AvrM_N PF18247.1 GAM17640.1 - 0.1 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain GATA PF00320.27 GAM17641.1 - 2e-16 59.3 5.3 3.7e-16 58.4 5.3 1.5 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 GAM17641.1 - 0.032 14.5 1.0 0.069 13.4 1.0 1.5 1 0 0 1 1 1 0 zinc-ribbon Pkinase_Tyr PF07714.17 GAM17642.1 - 3.3e-52 177.3 0.0 6.2e-52 176.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM17642.1 - 2.2e-44 151.8 0.0 5.7e-44 150.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain COR PF16095.5 GAM17642.1 - 2.8e-36 125.1 0.2 7.6e-36 123.8 0.0 1.8 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 GAM17642.1 - 2.9e-24 85.6 0.3 2.9e-24 85.6 0.3 2.5 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM17642.1 - 2.5e-14 53.2 0.4 7.5e-14 51.6 0.4 1.9 1 0 0 1 1 1 1 Ras family LRR_8 PF13855.6 GAM17642.1 - 2.4e-10 40.0 1.8 4.2e-08 32.8 1.0 3.2 1 1 1 2 2 2 2 Leucine rich repeat Arf PF00025.21 GAM17642.1 - 5.1e-10 39.1 0.9 2.8e-09 36.7 0.2 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family LRR_4 PF12799.7 GAM17642.1 - 1.8e-08 34.5 5.1 4.6e-05 23.7 1.9 3.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) Gtr1_RagA PF04670.12 GAM17642.1 - 0.00012 21.6 0.3 0.00097 18.6 0.1 2.6 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM17642.1 - 0.00013 22.0 0.0 0.00039 20.5 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAM17642.1 - 0.00019 22.0 0.1 0.0005 20.6 0.1 1.8 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 GAM17642.1 - 0.00022 21.2 2.5 0.026 14.4 0.3 3.1 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 GAM17642.1 - 0.0047 16.5 0.2 0.039 13.5 0.2 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.9 GAM17642.1 - 0.033 13.9 0.7 0.095 12.4 0.7 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation LRR_6 PF13516.6 GAM17642.1 - 0.05 13.7 6.5 0.11 12.6 0.2 3.8 3 0 0 3 3 3 0 Leucine Rich repeat AAA_7 PF12775.7 GAM17642.1 - 0.14 11.6 0.3 0.39 10.2 0.3 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region LRR_1 PF00560.33 GAM17642.1 - 0.59 10.9 7.3 30 5.7 0.0 4.8 4 0 0 4 4 3 0 Leucine Rich Repeat DUF3611 PF12263.8 GAM17643.1 - 0.039 13.8 4.4 0.036 14.0 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) LapA_dom PF06305.11 GAM17643.1 - 7 6.6 7.8 6.4 6.7 0.6 3.0 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain WD40 PF00400.32 GAM17644.1 - 1e-18 67.3 8.5 7.7e-07 29.7 0.0 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat BBE PF08031.12 GAM17645.1 - 6e-15 55.1 2.8 1.5e-14 53.8 2.8 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 GAM17646.1 - 6.3e-25 87.5 0.7 8.3e-25 87.1 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain BB_PF PF18063.1 GAM17647.1 - 4.4e-24 85.2 0.2 5.4e-24 84.9 0.2 1.1 1 0 0 1 1 1 1 Beta barrel Pore-forming domain SK_channel PF03530.14 GAM17648.1 - 5.7e-08 32.7 3.5 2.5e-07 30.7 3.5 2.1 1 1 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 GAM17648.1 - 0.14 12.1 6.5 0.54 10.3 6.5 2.0 1 1 0 1 1 1 0 Ion channel DUF4395 PF14340.6 GAM17648.1 - 0.25 11.7 3.8 4.8 7.5 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4395) Totivirus_coat PF05518.11 GAM17648.1 - 0.54 8.2 3.2 0.83 7.6 3.2 1.3 1 0 0 1 1 1 0 Totivirus coat protein Pex14_N PF04695.13 GAM17648.1 - 5.5 7.6 17.9 11 6.6 17.9 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SNAP PF14938.6 GAM17649.1 - 7.6e-109 363.5 15.5 8.6e-109 363.3 15.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 GAM17649.1 - 1.9e-10 40.9 12.3 4.7e-05 23.6 0.9 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM17649.1 - 6.8e-08 32.9 9.4 0.03 14.8 0.8 4.7 2 2 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM17649.1 - 4.4e-07 29.5 10.0 0.036 14.1 0.1 5.5 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM17649.1 - 3.2e-06 26.8 22.7 0.6 10.4 0.1 6.5 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 GAM17649.1 - 3.8e-06 27.2 21.1 0.26 12.0 0.3 6.2 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM17649.1 - 9.3e-06 25.2 3.1 1.4e-05 24.7 3.1 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 GAM17649.1 - 0.00027 20.9 23.4 0.014 15.5 0.3 5.9 5 1 1 7 7 7 2 Tetratricopeptide repeat RPN7 PF10602.9 GAM17649.1 - 0.00033 20.4 2.1 0.00033 20.4 2.1 2.5 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_14 PF13428.6 GAM17649.1 - 0.00042 20.9 10.0 1.2 10.2 0.4 4.8 3 1 2 5 5 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAM17649.1 - 0.00084 18.7 2.4 1.7 8.2 0.0 3.7 3 0 0 3 3 3 2 SHNi-TPR TPR_1 PF00515.28 GAM17649.1 - 0.00096 18.9 23.3 0.46 10.4 0.4 6.3 6 1 0 7 7 7 3 Tetratricopeptide repeat Spatacsin_C PF14649.6 GAM17649.1 - 0.0014 17.8 7.4 0.0032 16.6 0.6 2.5 1 1 0 2 2 2 1 Spatacsin C-terminus TPR_10 PF13374.6 GAM17649.1 - 0.0015 18.3 5.1 2.9 7.9 0.1 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat DHR-2 PF06920.13 GAM17649.1 - 0.0025 16.5 1.7 0.0047 15.6 0.9 1.8 1 1 0 2 2 2 1 Dock homology region 2 ANAPC3 PF12895.7 GAM17649.1 - 0.0051 17.0 11.8 0.054 13.7 0.2 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAM17649.1 - 0.006 17.2 13.9 0.12 13.1 1.3 4.4 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM17649.1 - 0.023 14.4 15.2 1.2 8.9 0.1 4.4 4 0 0 4 4 4 0 TPR repeat DUF2225 PF09986.9 GAM17649.1 - 0.11 12.2 9.1 0.19 11.4 2.3 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) SH3BP5 PF05276.14 GAM17649.1 - 3.7 7.3 7.9 1.2 8.9 2.4 2.5 1 1 1 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) TPR_3 PF07720.12 GAM17649.1 - 5.6 7.1 15.0 19 5.4 0.1 5.4 4 2 0 5 5 5 0 Tetratricopeptide repeat CBS PF00571.28 GAM17650.1 - 1.8e-29 101.9 2.1 1.2e-07 32.0 0.1 4.3 4 0 0 4 4 4 4 CBS domain Sarcoglycan_2 PF05510.13 GAM17651.1 - 1.3 7.7 7.3 1.9 7.2 7.3 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF3862 PF12978.7 GAM17652.1 - 0.035 13.9 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3862) SKG6 PF08693.10 GAM17652.1 - 0.11 12.0 0.2 0.25 10.8 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EMA PF02488.15 GAM17652.1 - 0.12 12.1 1.0 0.66 9.6 0.1 2.0 1 1 1 2 2 2 0 Merozoite Antigen Chlam_PMP PF02415.17 GAM17652.1 - 0.25 11.9 50.5 0.13 12.8 1.5 9.0 9 0 0 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Spt20 PF12090.8 GAM17653.1 - 0.0044 16.7 19.9 7.4 6.1 0.0 2.5 2 1 0 2 2 2 1 Spt20 family eIF-3_zeta PF05091.12 GAM17653.1 - 0.0049 15.9 9.9 0.0077 15.3 9.9 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 GAM17653.1 - 0.081 12.7 3.5 0.24 11.1 3.4 1.8 2 0 0 2 2 2 0 Connexin Na_trans_assoc PF06512.13 GAM17653.1 - 0.19 12.0 9.3 0.021 15.1 2.1 2.7 2 2 0 2 2 2 0 Sodium ion transport-associated Comm PF15957.5 GAM17653.1 - 0.38 11.1 0.0 0.38 11.1 0.0 2.5 2 0 0 2 2 2 0 Commissureless DUF4175 PF13779.6 GAM17653.1 - 1.2 7.0 11.7 2 6.3 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Sec62 PF03839.16 GAM17653.1 - 2.2 7.7 7.8 88 2.5 8.8 2.5 2 0 0 2 2 2 0 Translocation protein Sec62 V_ATPase_I PF01496.19 GAM17653.1 - 3 5.6 7.9 5.4 4.8 7.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 GAM17653.1 - 6.5 6.0 8.5 23 4.2 8.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2185 PF09951.9 GAM17654.1 - 4.4e-30 103.3 0.1 5.2e-29 99.9 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2185) DUF2314 PF10077.9 GAM17654.1 - 6.4e-07 29.5 0.3 1.6e-06 28.2 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2314) SCAI PF12070.8 GAM17654.1 - 0.029 13.3 2.2 0.036 12.9 2.2 1.2 1 0 0 1 1 1 0 Protein SCAI Mem_trans PF03547.18 GAM17654.1 - 0.28 9.5 4.9 0.4 9.0 4.9 1.1 1 0 0 1 1 1 0 Membrane transport protein ASD2 PF08687.11 GAM17654.1 - 0.8 9.2 5.4 1.2 8.7 5.4 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Presenilin PF01080.17 GAM17654.1 - 0.93 8.2 5.7 1.1 7.9 5.7 1.1 1 0 0 1 1 1 0 Presenilin Opy2 PF09463.10 GAM17655.1 - 0.12 12.7 40.1 5 7.5 9.8 4.8 1 1 3 4 4 4 0 Opy2 protein TILa PF12714.7 GAM17655.1 - 0.54 10.3 26.4 0.16 12.0 1.6 4.1 2 2 2 4 4 4 0 TILa domain FNIP PF05725.12 GAM17656.1 - 2.3e-26 91.7 2.0 1.7e-11 44.1 0.0 4.5 2 1 1 4 4 4 4 FNIP Repeat Rad60-SLD PF11976.8 GAM17657.1 - 7.8e-11 41.7 0.0 8.6e-11 41.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAM17657.1 - 7.6e-09 35.2 0.0 7.8e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM17658.1 - 6.1e-14 51.6 0.0 7.4e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAM17658.1 - 8.6e-05 22.2 0.0 0.0001 22.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family MMR_HSR1 PF01926.23 GAM17659.1 - 4.6e-19 68.6 0.0 1.1e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM17659.1 - 2.5e-10 40.1 0.0 4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAM17659.1 - 5.4e-07 29.8 0.6 0.00067 19.8 0.1 3.1 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 GAM17659.1 - 5.5e-07 29.6 0.2 9.5e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 GAM17659.1 - 3.3e-06 26.8 0.6 0.0014 18.2 0.3 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 GAM17659.1 - 0.00019 20.8 1.0 0.0008 18.8 0.1 2.2 2 1 0 2 2 2 1 AIG1 family Septin PF00735.18 GAM17659.1 - 0.0049 16.2 4.5 0.06 12.6 0.0 2.8 3 0 0 3 3 3 1 Septin ABC_tran PF00005.27 GAM17659.1 - 0.017 15.6 0.1 0.057 13.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Arf PF00025.21 GAM17659.1 - 0.019 14.4 0.3 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family SRPRB PF09439.10 GAM17659.1 - 0.022 14.2 0.0 0.049 13.1 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 GAM17659.1 - 0.028 14.2 0.1 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 GAM17659.1 - 0.03 14.5 0.0 0.079 13.2 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF382 PF04037.13 GAM17659.1 - 0.099 12.8 6.0 3.2 7.9 1.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF382) ABC_membrane PF00664.23 GAM17660.1 - 2.4e-52 178.3 10.2 3.5e-52 177.7 10.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAM17660.1 - 6e-36 124.0 0.0 1.5e-35 122.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAM17660.1 - 1e-06 28.4 0.0 2.1e-05 24.1 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAM17660.1 - 0.0015 18.9 0.1 0.0036 17.7 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM17660.1 - 0.0034 17.7 0.1 0.021 15.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM17660.1 - 0.0035 17.1 0.2 0.012 15.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 GAM17660.1 - 0.0053 17.2 0.0 0.036 14.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAM17660.1 - 0.021 14.5 0.0 0.056 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAM17660.1 - 0.024 14.7 0.0 3 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_membrane_3 PF13748.6 GAM17660.1 - 0.031 13.5 0.2 0.066 12.4 0.2 1.5 1 0 0 1 1 1 0 ABC transporter transmembrane region IstB_IS21 PF01695.17 GAM17660.1 - 0.049 13.4 0.2 0.78 9.4 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 GAM17660.1 - 0.053 12.8 0.1 0.23 10.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 GAM17660.1 - 0.054 13.2 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM17660.1 - 0.059 13.3 0.0 0.059 13.3 0.0 1.9 2 0 0 2 2 1 0 RsgA GTPase AAA_18 PF13238.6 GAM17660.1 - 0.067 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 GAM17660.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 GAM17660.1 - 0.11 12.1 0.1 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 GAM17660.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain DUF5407 PF17401.2 GAM17661.1 - 0.9 9.8 2.9 1.1 9.6 0.1 2.5 4 0 0 4 4 4 0 Family of unknown function (DUF5407) Actin PF00022.19 GAM17663.1 - 2.7e-152 507.1 0.0 8.6e-152 505.5 0.0 1.6 1 1 0 1 1 1 1 Actin TLD PF07534.16 GAM17664.1 - 1e-35 123.0 1.0 1e-35 123.0 1.0 3.7 4 0 0 4 4 4 1 TLD WD40 PF00400.32 GAM17664.1 - 5.2e-10 39.8 27.1 0.06 14.2 0.1 6.3 5 0 0 5 5 5 4 WD domain, G-beta repeat LysM PF01476.20 GAM17664.1 - 3.2e-06 27.1 0.0 3.6e-05 23.7 0.0 2.8 2 0 0 2 2 2 1 LysM domain ANAPC4_WD40 PF12894.7 GAM17664.1 - 0.00051 20.3 6.5 0.08 13.2 1.0 3.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GRAM PF02893.20 GAM17664.1 - 0.00067 19.5 2.4 0.00074 19.4 0.2 2.2 2 0 0 2 2 2 1 GRAM domain Thioredoxin PF00085.20 GAM17665.1 - 2.1e-24 85.5 0.0 4.5e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.20 GAM17665.1 - 1.4e-15 57.2 0.0 2.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain ZZ PF00569.17 GAM17665.1 - 2.1e-11 43.4 6.1 4.1e-11 42.5 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type UBA PF00627.31 GAM17665.1 - 8.2e-09 35.2 0.1 1.5e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Thioredoxin_8 PF13905.6 GAM17665.1 - 3.3e-06 27.3 0.0 1.8e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 GAM17665.1 - 0.00029 20.3 0.2 0.0005 19.5 0.2 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Atg14 PF10186.9 GAM17665.1 - 0.00056 19.1 15.7 0.00085 18.5 15.7 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Thioredoxin_2 PF13098.6 GAM17665.1 - 0.0019 18.6 3.2 0.0032 17.9 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain C1_2 PF03107.16 GAM17665.1 - 0.0019 18.5 4.9 0.0042 17.4 4.9 1.6 1 0 0 1 1 1 1 C1 domain AhpC-TSA PF00578.21 GAM17665.1 - 0.002 18.1 0.9 0.0041 17.0 0.0 1.9 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 GAM17665.1 - 0.0055 16.9 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 GAM17665.1 - 0.0068 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Redoxin Asp-B-Hydro_N PF05279.11 GAM17665.1 - 0.013 15.5 8.5 0.019 15.1 8.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CEBP_ZZ PF16366.5 GAM17665.1 - 0.096 12.9 3.7 0.22 11.8 3.7 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain NODP PF07684.12 GAM17665.1 - 0.11 12.7 0.1 0.34 11.1 0.1 1.8 2 0 0 2 2 2 0 NOTCH protein Thioredoxin_9 PF14595.6 GAM17665.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.2 2 1 0 2 2 1 0 Thioredoxin AAA_15 PF13175.6 GAM17665.1 - 0.26 10.9 7.2 0.38 10.4 7.2 1.1 1 0 0 1 1 1 0 AAA ATPase domain zf-UBR PF02207.20 GAM17665.1 - 0.36 11.0 4.9 0.85 9.8 4.9 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Afi1 PF07792.12 GAM17665.1 - 0.98 9.9 7.5 2.2 8.8 7.5 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Dsh_C PF12316.8 GAM17665.1 - 1.9 8.9 7.2 0.4 11.1 2.5 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal MIT_C PF16565.5 GAM17666.1 - 5.1e-36 123.8 0.3 7.1e-36 123.3 0.3 1.2 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT PI3K_1B_p101 PF10486.9 GAM17667.1 - 0.0011 16.9 0.5 0.0011 16.9 0.5 3.3 3 0 0 3 3 3 2 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FYDLN_acid PF09538.10 GAM17667.1 - 2.8 8.6 6.3 0.45 11.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) ADK PF00406.22 GAM17668.1 - 9.8e-10 38.7 3.0 1.5e-08 34.9 3.0 2.6 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAM17668.1 - 1.5e-08 35.2 0.2 8e-08 32.8 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM17668.1 - 0.00011 22.7 0.0 0.00031 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAM17668.1 - 0.11 11.8 0.2 0.53 9.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 GAM17668.1 - 0.46 10.7 1.7 7 6.9 0.1 2.7 3 0 0 3 3 3 0 AAA domain LRR_9 PF14580.6 GAM17669.1 - 2.4e-09 36.9 0.2 3.7e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 GAM17669.1 - 1.2e-06 28.2 1.3 2.7e-06 27.1 0.9 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 GAM17669.1 - 2.1e-05 24.7 2.2 0.076 13.5 0.1 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) DUF3557 PF12078.8 GAM17669.1 - 0.035 14.1 0.2 0.057 13.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) LRR_1 PF00560.33 GAM17669.1 - 0.075 13.6 0.9 21 6.1 0.0 3.0 2 1 0 2 2 2 0 Leucine Rich Repeat MCPVI PF02993.14 GAM17669.1 - 1.5 8.6 4.4 2.3 8.0 4.4 1.4 1 0 0 1 1 1 0 Minor capsid protein VI FNIP PF05725.12 GAM17670.1 - 1.8e-113 370.5 22.4 4.2e-14 52.4 4.5 10.6 4 3 10 14 14 14 12 FNIP Repeat F-box PF00646.33 GAM17670.1 - 2 8.4 4.5 0.68 9.9 1.0 2.1 2 0 0 2 2 2 0 F-box domain FAD_binding_3 PF01494.19 GAM17671.1 - 4.6e-19 68.9 0.0 9.4e-10 38.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAM17671.1 - 5.2e-07 29.6 0.0 0.0001 22.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM17671.1 - 1.7e-05 24.9 0.0 5.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM17671.1 - 0.0068 15.7 0.0 0.052 12.8 0.0 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM17671.1 - 0.0079 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 GAM17671.1 - 0.021 13.9 0.0 0.51 9.3 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 GAM17671.1 - 0.023 13.4 0.0 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.24 GAM17671.1 - 0.1 11.9 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GAM17671.1 - 0.18 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FNIP PF05725.12 GAM17672.1 - 1.6e-117 383.5 41.4 6.5e-15 55.0 0.2 13.3 5 4 2 13 13 13 12 FNIP Repeat DUF1769 PF08588.10 GAM17672.1 - 0.4 10.9 10.7 60 4.0 0.0 7.2 9 1 1 10 10 10 0 Protein of unknown function (DUF1769) Glyco_hydro_65C PF03633.15 GAM17672.1 - 0.99 9.4 3.7 55 3.8 0.0 5.3 7 0 0 7 7 7 0 Glycosyl hydrolase family 65, C-terminal domain Band_7 PF01145.25 GAM17673.1 - 4.1e-26 92.1 0.6 5.8e-26 91.6 0.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 GAM17673.1 - 0.044 13.9 0.4 0.076 13.2 0.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 FNIP PF05725.12 GAM17674.1 - 1e-75 249.7 47.9 1.3e-11 44.5 0.1 11.0 8 3 5 14 14 14 12 FNIP Repeat Glyco_hydro_65C PF03633.15 GAM17674.1 - 0.013 15.4 0.0 1.4 8.9 0.0 4.3 5 0 0 5 5 5 0 Glycosyl hydrolase family 65, C-terminal domain Rad60-SLD PF11976.8 GAM17675.1 - 8.1e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAM17675.1 - 0.0011 18.7 0.6 0.0036 17.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Nsp1_C PF05064.13 GAM17675.1 - 0.057 13.2 0.1 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region Endotoxin_N PF03945.14 GAM17676.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.5 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.14 GAM17677.1 - 7e-23 81.5 0.2 1.1e-22 80.9 0.2 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain MbeB_N PF04837.12 GAM17677.1 - 0.00026 21.2 1.1 0.00055 20.2 1.1 1.5 1 0 0 1 1 1 1 MbeB-like, N-term conserved region CBM_6 PF03422.15 GAM17677.1 - 0.12 12.7 0.1 0.36 11.1 0.1 1.9 1 1 0 1 1 1 0 Carbohydrate binding module (family 6) E1-E2_ATPase PF00122.20 GAM17678.1 - 5.2e-36 123.9 3.8 1.4e-35 122.4 1.2 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAM17678.1 - 4.2e-18 66.4 0.0 1.2e-17 64.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM17678.1 - 1.6e-14 53.3 0.0 5.7e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 GAM17678.1 - 3.5e-14 52.9 9.6 3.5e-14 52.9 9.6 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GAM17678.1 - 4.9e-08 32.9 0.1 1.2e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM17678.1 - 0.0019 18.0 0.1 0.07 12.9 0.1 2.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2768 PF10966.8 GAM17678.1 - 0.016 15.6 1.1 0.073 13.5 1.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) TMEM100 PF16311.5 GAM17678.1 - 0.031 13.9 0.3 0.1 12.2 0.3 1.9 1 0 0 1 1 1 0 Transmembrane protein 100 PIRT PF15099.6 GAM17678.1 - 0.095 12.3 1.2 0.29 10.7 0.3 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF2046 PF09755.9 GAM17679.1 - 1e-13 51.2 35.1 1.7e-12 47.2 26.1 2.1 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) QSOX_Trx1 PF18108.1 GAM17679.1 - 0.0061 16.7 3.5 0.11 12.7 2.6 2.3 2 1 0 2 2 2 1 QSOX Trx-like domain CENP-F_leu_zip PF10473.9 GAM17679.1 - 2.8 8.0 35.1 0.12 12.4 8.6 3.1 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3573 PF12097.8 GAM17679.1 - 3 6.6 5.8 10 4.9 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) GAS PF13851.6 GAM17679.1 - 4.1 6.7 31.5 0.91 8.8 24.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 GAM17679.1 - 7.6 5.5 23.3 2.3e+02 0.7 23.0 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Vps52 PF04129.12 GAM17680.1 - 5e-52 177.3 25.5 1.1e-51 176.1 25.5 1.6 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 GAM17680.1 - 2.1e-08 33.1 28.5 1.5e-06 27.0 5.2 3.5 2 1 1 3 3 3 3 Exocyst complex component Sec3 Nitr_red_bet_C PF14711.6 GAM17680.1 - 0.1 12.3 0.8 0.43 10.3 0.3 2.2 2 0 0 2 2 2 0 Respiratory nitrate reductase beta C-terminal COG2 PF06148.11 GAM17680.1 - 0.73 9.9 6.0 1.6 8.8 3.3 2.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Alpha_kinase PF02816.18 GAM17681.1 - 1.4e-58 198.0 0.0 1.4e-58 198.0 0.0 2.4 2 1 1 3 3 3 1 Alpha-kinase family WD40 PF00400.32 GAM17681.1 - 1.9e-30 104.4 17.6 3.2e-05 24.6 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat WD40_like PF17005.5 GAM17681.1 - 2.6e-08 33.6 2.3 0.0021 17.4 0.3 2.3 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 GAM17681.1 - 5.4e-07 28.6 15.7 0.013 14.2 0.3 6.3 4 1 2 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAM17681.1 - 0.00071 19.8 0.4 13 6.2 0.0 4.4 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAM17681.1 - 0.0025 18.2 0.0 5.9 7.5 0.0 4.4 5 0 0 5 5 5 1 PQQ-like domain DUF4080 PF13311.6 GAM17681.1 - 5.9 7.0 13.1 2 8.6 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4080) Ank_2 PF12796.7 GAM17682.1 - 2.2e-29 101.8 2.8 2.2e-15 57.0 0.4 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM17682.1 - 9.7e-27 93.0 3.4 9e-11 42.1 0.0 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM17682.1 - 2.3e-26 88.9 4.4 2.2e-05 24.5 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GAM17682.1 - 5.8e-25 87.0 9.5 2.1e-10 40.6 0.1 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM17682.1 - 4.5e-24 83.8 7.9 6.2e-06 26.4 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Methyltransf_2 PF00891.18 GAM17683.1 - 1.2e-40 139.1 0.0 1.4e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 GAM17683.1 - 0.00073 19.4 0.0 0.0045 16.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM17683.1 - 0.05 14.3 0.0 0.42 11.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Dimerisation2 PF16864.5 GAM17683.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_11 PF08241.12 GAM17683.1 - 0.16 12.7 0.0 0.4 11.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Endotoxin_N PF03945.14 GAM17684.1 - 3.6e-20 72.6 0.1 5.9e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain MbeB_N PF04837.12 GAM17684.1 - 0.00038 20.7 0.9 0.00083 19.6 0.9 1.5 1 0 0 1 1 1 1 MbeB-like, N-term conserved region Pkinase PF00069.25 GAM17685.1 - 4.4e-36 124.6 2.5 4.5e-36 124.6 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17685.1 - 2.1e-14 53.4 0.0 7.2e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.6 GAM17685.1 - 3.4e-06 27.3 6.3 7.9e-06 26.1 6.3 1.7 1 0 0 1 1 1 1 Ring finger domain Kinase-like PF14531.6 GAM17685.1 - 3.7e-06 26.5 0.3 1.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like zf-RING_UBOX PF13445.6 GAM17685.1 - 5.9e-06 26.2 2.5 5.5e-05 23.1 0.9 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAM17685.1 - 1.4e-05 24.9 7.1 3.9e-05 23.4 7.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM17685.1 - 0.00025 20.9 3.6 0.00055 19.7 3.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM17685.1 - 0.00071 19.5 6.6 0.0017 18.3 6.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM17685.1 - 0.0028 17.4 8.8 0.011 15.5 8.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERM PF00769.19 GAM17685.1 - 0.039 13.8 61.7 0.077 12.8 30.0 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family zf-Nse PF11789.8 GAM17685.1 - 0.078 12.8 2.7 0.28 11.0 2.7 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Tropomyosin_1 PF12718.7 GAM17685.1 - 0.36 11.0 52.0 0.17 12.0 7.5 3.4 1 1 3 4 4 4 0 Tropomyosin like FANCL_C PF11793.8 GAM17685.1 - 0.39 10.9 3.3 0.88 9.8 3.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.7 GAM17685.1 - 0.51 10.7 4.3 1.7 9.0 4.3 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAM17685.1 - 0.9 9.5 4.9 2.7 7.9 5.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 APG6_N PF17675.1 GAM17685.1 - 1.5 9.3 61.4 0.26 11.8 21.1 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region GBP_C PF02841.14 GAM17685.1 - 1.8 7.9 46.0 0.17 11.3 12.9 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain zf-C3HC4_4 PF15227.6 GAM17685.1 - 2.2 8.5 8.5 0.41 10.8 3.3 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Tropomyosin PF00261.20 GAM17685.1 - 9.3 5.5 52.7 0.094 12.1 22.4 2.8 1 1 2 3 3 3 0 Tropomyosin zf-RING_4 PF14570.6 GAM17685.1 - 10 6.0 10.4 0.33 10.8 2.8 2.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain CAF1A PF12253.8 GAM17686.1 - 2.6e-22 78.8 7.8 2.6e-22 78.8 7.8 5.6 2 2 0 2 2 2 1 Chromatin assembly factor 1 subunit A Mic1 PF07035.12 GAM17687.1 - 1.6e-47 161.1 6.5 4.5e-47 159.7 6.5 1.8 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like TraG_N PF07916.11 GAM17687.1 - 2.9 6.7 7.9 6.3 5.5 7.9 1.5 1 0 0 1 1 1 0 TraG-like protein, N-terminal region SAC3_GANP PF03399.16 GAM17688.1 - 2.9e-91 305.9 1.5 2.9e-91 305.9 1.5 2.0 2 0 0 2 2 2 1 SAC3/GANP family MCM3AP_GANP PF16769.5 GAM17688.1 - 4.2e-10 38.5 3.3 4.2e-10 38.5 3.3 3.4 4 0 0 4 4 4 2 MCM3AP domain of GANP CSN8_PSD8_EIF3K PF10075.9 GAM17688.1 - 3.5e-07 30.3 0.0 1.1e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RRM_1 PF00076.22 GAM17688.1 - 0.0011 18.8 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YihI PF04220.12 GAM17688.1 - 0.056 13.2 0.3 0.5 10.1 0.0 2.3 2 0 0 2 2 2 0 Der GTPase activator (YihI) AlaDh_PNT_N PF05222.15 GAM17688.1 - 0.075 13.3 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain Syja_N PF02383.18 GAM17690.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain TPR_12 PF13424.6 GAM17691.1 - 1.9e-08 34.5 2.2 5.8e-06 26.5 0.3 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF2075 PF09848.9 GAM17691.1 - 0.032 13.5 0.0 4 6.6 0.0 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CcdA PF07362.12 GAM17691.1 - 0.059 13.8 0.5 3.2 8.2 0.3 2.3 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA TPR_10 PF13374.6 GAM17691.1 - 0.062 13.2 0.2 0.52 10.2 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PyocinActivator PF11112.8 GAM17691.1 - 0.075 13.2 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Pyocin activator protein PrtN TPR_1 PF00515.28 GAM17691.1 - 3.3 7.7 6.8 5.3 7.0 0.5 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Spt5-NGN PF03439.13 GAM17692.1 - 2.2e-21 75.6 0.0 4.8e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 GAM17692.1 - 4e-17 61.5 27.1 2.8e-06 27.1 0.1 7.9 8 0 0 8 8 8 5 KOW motif SH3_15 PF18346.1 GAM17692.1 - 0.075 13.4 1.5 34 4.9 0.0 3.8 4 0 0 4 4 4 0 Mind bomb SH3 repeat domain SH3_2 PF07653.17 GAM17692.1 - 0.097 12.4 0.2 0.77 9.5 0.2 2.6 1 1 0 1 1 1 0 Variant SH3 domain DUF2187 PF09953.9 GAM17692.1 - 0.31 11.1 0.1 0.31 11.1 0.1 3.0 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2187) DUF3912 PF13051.6 GAM17692.1 - 1.1 9.6 5.6 3.3 8.0 0.0 4.2 6 0 0 6 6 6 0 Protein of unknown function (DUF3912) zf-RING_2 PF13639.6 GAM17693.1 - 4.4e-06 26.9 6.3 5.4e-05 23.4 3.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 GAM17693.1 - 3.8e-05 23.9 2.8 3.8e-05 23.9 2.8 2.5 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAM17693.1 - 0.00077 19.3 2.7 0.0041 17.0 2.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM17693.1 - 0.0019 18.0 4.9 0.0077 16.1 2.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAM17693.1 - 0.0072 16.1 4.3 0.066 13.0 1.3 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 GAM17693.1 - 0.011 15.7 1.5 0.011 15.7 1.5 2.1 2 0 0 2 2 2 0 zinc-RING finger domain DZR PF12773.7 GAM17693.1 - 0.016 15.2 0.5 0.047 13.7 0.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon Vma12 PF11712.8 GAM17693.1 - 0.076 13.1 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-C3HC4_3 PF13920.6 GAM17693.1 - 0.12 12.3 4.8 0.22 11.4 2.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAM17693.1 - 0.24 11.1 6.7 0.077 12.6 3.1 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type AAA_18 PF13238.6 GAM17693.1 - 0.29 11.7 1.8 0.44 11.1 1.8 1.3 1 0 0 1 1 1 0 AAA domain zf-RING_UBOX PF13445.6 GAM17693.1 - 0.3 11.2 3.5 0.37 10.8 1.3 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 GAM17693.1 - 0.34 10.8 6.7 0.84 9.6 4.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 SUIM_assoc PF16619.5 GAM17693.1 - 0.53 10.4 11.2 0.9 9.6 11.2 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 GAM17693.1 - 0.76 8.6 6.0 1.1 8.1 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) zf-C3HC4_4 PF15227.6 GAM17693.1 - 1.4 9.2 5.8 0.56 10.4 2.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 GAM17693.1 - 4.5 7.4 8.2 6.8 6.8 3.9 2.8 2 1 0 2 2 2 0 Zinc-finger Spt20 PF12090.8 GAM17693.1 - 4.6 6.8 13.0 7.3 6.1 13.0 1.2 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 GAM17693.1 - 6.1 5.9 11.4 8.7 5.4 11.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Methyltransf_23 PF13489.6 GAM17694.1 - 6e-11 42.5 0.0 1.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM17694.1 - 1.6e-10 41.5 0.0 3.1e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM17694.1 - 1.2e-07 31.7 0.0 3.8e-06 26.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM17694.1 - 1.5e-07 32.1 0.1 4.8e-07 30.4 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM17694.1 - 8.2e-07 29.6 0.0 3.9e-06 27.5 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain DNA_methylase PF00145.17 GAM17695.1 - 3.4e-39 135.1 0.2 1.2e-28 100.4 0.6 2.0 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 GAM17695.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase HEM4 PF02602.15 GAM17695.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD DUF2779 PF11074.8 GAM17696.1 - 0.017 15.6 0.5 0.048 14.1 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) COG7 PF10191.9 GAM17697.1 - 4.4e-98 329.5 19.9 2.4e-74 251.0 14.9 2.2 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) Focal_AT PF03623.13 GAM17697.1 - 0.0093 16.0 1.9 0.17 11.9 0.3 3.2 2 0 0 2 2 2 1 Focal adhesion targeting region E1_DerP2_DerF2 PF02221.15 GAM17699.1 - 8.8e-22 78.0 0.1 1e-21 77.8 0.1 1.0 1 0 0 1 1 1 1 ML domain Peptidase_M28 PF04389.17 GAM17700.1 - 1.3e-21 77.2 0.1 2.1e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAM17700.1 - 1.4e-09 37.9 0.1 3.7e-09 36.6 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 GAM17700.1 - 0.016 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Ank_2 PF12796.7 GAM17701.1 - 9e-18 64.6 1.8 9.8e-09 35.7 0.6 4.5 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM17701.1 - 4.2e-11 42.0 2.2 2.5 8.9 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 GAM17701.1 - 6.1e-10 39.4 4.2 0.06 14.0 0.3 7.2 4 3 4 8 8 8 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM17701.1 - 6.3e-10 39.1 0.1 3.6 8.0 0.0 6.9 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM17701.1 - 0.0016 18.8 1.0 28 5.4 0.0 5.3 6 0 0 6 6 6 1 Ankyrin repeat DUF1843 PF08898.10 GAM17701.1 - 0.11 13.1 0.0 12 6.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) CompInhib_SCIN PF11546.8 GAM17702.1 - 0.039 14.0 0.5 0.15 12.1 0.5 2.0 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN DUF5344 PF17279.2 GAM17702.1 - 2.3 8.8 5.3 2.5 8.7 1.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5344) tRNA-synt_1 PF00133.22 GAM17703.1 - 1.1e-219 730.7 0.6 1.4e-219 730.3 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM17703.1 - 3.7e-22 78.9 0.1 7.9e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM17703.1 - 1.3e-15 57.1 3.4 0.00041 19.2 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAM17703.1 - 0.00047 19.6 0.0 0.00089 18.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 GAM17703.1 - 0.022 14.3 0.2 0.054 13.0 0.0 1.8 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 Spt20 PF12090.8 GAM17704.1 - 7.3e-22 78.1 19.5 7.3e-22 78.1 19.5 5.6 2 2 1 3 3 3 1 Spt20 family Indigoidine_A PF04227.12 GAM17704.1 - 0.21 10.9 5.6 0.42 9.9 5.6 1.4 1 0 0 1 1 1 0 Indigoidine synthase A like protein OmpH PF03938.14 GAM17704.1 - 1.5 9.2 49.1 1.4 9.2 38.1 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PPR_2 PF13041.6 GAM17706.1 - 4.5e-17 62.0 1.1 0.0034 17.5 0.0 4.8 3 1 1 4 4 4 4 PPR repeat family PPR PF01535.20 GAM17706.1 - 1.4e-08 34.4 4.2 0.44 10.9 0.0 5.9 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.6 GAM17706.1 - 0.0004 20.4 0.0 0.94 9.6 0.0 3.1 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAM17706.1 - 0.002 17.5 0.4 0.027 13.8 0.0 2.5 1 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GAM17706.1 - 0.0021 18.5 0.0 1.5 9.4 0.0 3.4 2 1 2 4 4 4 1 Tetratricopeptide repeat Daxx PF03344.15 GAM17706.1 - 0.0046 17.0 0.1 0.34 11.0 0.0 2.4 2 0 0 2 2 2 1 Daxx N-terminal Rassf1C-interacting domain PPR_1 PF12854.7 GAM17706.1 - 0.033 13.9 0.1 1.5 8.6 0.0 3.4 4 0 0 4 4 4 0 PPR repeat Clathrin PF00637.20 GAM17706.1 - 0.05 13.5 0.0 17 5.2 0.0 3.2 1 1 1 2 2 2 0 Region in Clathrin and VPS Aldo_ket_red PF00248.21 GAM17707.1 - 3.3e-80 269.4 0.0 3.9e-80 269.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_8 PF05148.15 GAM17707.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase DDE_Tnp_1_6 PF13751.6 GAM17707.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain EVE PF01878.18 GAM17708.1 - 0.048 13.7 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 EVE domain DUF5009 PF16401.5 GAM17710.1 - 1.2e-09 38.0 0.8 1.2e-09 38.0 0.8 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF5009) zf_Hakai PF18408.1 GAM17710.1 - 0.016 14.9 0.4 0.24 11.1 0.6 2.3 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain DUF4279 PF14106.6 GAM17710.1 - 0.21 11.8 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) DUF2244 PF10003.9 GAM17710.1 - 0.23 11.1 0.1 0.23 11.1 0.1 3.3 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) DUF5134 PF17197.4 GAM17710.1 - 3.1 7.7 5.9 13 5.7 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5134) HlyIII PF03006.20 GAM17711.1 - 1.4e-59 201.5 23.8 1.7e-59 201.2 23.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4611 PF15387.6 GAM17711.1 - 1.8 8.8 7.9 0.2 11.9 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) WD40 PF00400.32 GAM17712.1 - 7.9e-43 143.6 23.1 4e-07 30.6 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 GAM17712.1 - 2.3e-12 46.6 1.9 4.7e-12 45.6 1.9 1.6 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 GAM17712.1 - 3.6e-10 39.7 2.3 1.8e-05 24.2 0.1 2.2 1 1 1 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 GAM17712.1 - 4e-10 39.9 4.0 0.00086 19.6 0.1 5.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAM17712.1 - 6.4e-09 35.8 0.1 0.27 11.3 0.0 4.6 2 2 2 4 4 4 3 Ciliary BBSome complex subunit 2, middle region F-box PF00646.33 GAM17712.1 - 1.3e-07 31.3 3.5 2.9e-07 30.2 3.5 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 GAM17712.1 - 0.047 12.3 11.5 10 4.7 0.3 4.9 2 1 3 5 5 5 0 Nucleoporin Nup120/160 RSN1_7TM PF02714.15 GAM17713.1 - 5.9e-70 235.7 32.3 5.9e-70 235.7 32.3 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAM17713.1 - 3.2e-38 131.0 3.1 3.2e-38 131.0 3.1 3.4 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAM17713.1 - 1.1e-24 87.7 0.6 1.5e-24 87.2 0.6 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF1836 PF08876.11 GAM17713.1 - 0.077 13.0 1.0 4.9 7.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) tRNA_U5-meth_tr PF05958.11 GAM17714.1 - 5.1e-18 65.2 0.0 8.3e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GAM17714.1 - 1.6e-09 37.7 0.1 5.1e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM17714.1 - 5.6e-08 33.4 0.2 1.7e-07 31.8 0.2 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM17714.1 - 9.5e-05 21.8 0.1 0.00019 20.9 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAM17714.1 - 0.0001 23.0 0.3 0.26 12.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAM17714.1 - 0.0001 22.9 0.1 0.00034 21.2 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM17714.1 - 0.00012 21.6 0.1 0.00023 20.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 GAM17714.1 - 0.00027 20.6 0.0 0.0018 17.9 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 GAM17714.1 - 0.0004 20.0 0.1 0.00099 18.7 0.1 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 GAM17714.1 - 0.00098 18.6 0.4 0.002 17.6 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 GAM17714.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 GAM17714.1 - 0.0029 17.5 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAM17714.1 - 0.0043 16.8 0.0 0.0079 16.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein N6_N4_Mtase PF01555.18 GAM17714.1 - 0.0085 15.8 0.1 0.036 13.8 0.0 1.9 2 0 0 2 2 2 1 DNA methylase Methyltransf_32 PF13679.6 GAM17714.1 - 0.019 14.9 0.1 0.052 13.5 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 GAM17714.1 - 0.019 14.4 0.1 0.036 13.5 0.1 1.4 1 0 0 1 1 1 0 Putative methyltransferase TPMT PF05724.11 GAM17714.1 - 0.095 12.3 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) SET PF00856.28 GAM17715.1 - 2.8e-14 53.8 0.4 1.5e-13 51.5 0.0 2.1 2 0 0 2 2 2 1 SET domain TPR_8 PF13181.6 GAM17715.1 - 3.1e-05 23.9 0.7 0.00063 19.7 0.6 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM17715.1 - 0.00031 20.6 3.7 0.0052 16.8 0.8 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM17715.1 - 0.0015 18.3 1.4 0.026 14.3 1.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM17715.1 - 0.0042 17.6 0.2 0.018 15.5 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM17715.1 - 0.0069 16.7 0.9 0.049 13.9 0.9 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.18 GAM17715.1 - 0.19 11.8 2.5 0.84 9.7 0.1 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain UCR_14kD PF02271.16 GAM17716.1 - 1.4e-18 66.7 0.3 1.6e-18 66.5 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Nucleolin_bd PF16725.5 GAM17716.1 - 0.041 13.5 0.5 1.4 8.6 0.2 2.7 2 1 1 3 3 3 0 Nucleolin binding domain Adenylsucc_synt PF00709.21 GAM17717.1 - 4e-178 592.6 0.0 4.6e-178 592.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase HAD_2 PF13419.6 GAM17718.1 - 1.2e-12 48.2 0.0 1.7e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM17718.1 - 2e-06 28.3 0.1 0.00012 22.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM17718.1 - 0.0022 18.0 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 GAM17718.1 - 0.055 13.3 0.0 8 6.3 0.0 2.3 2 0 0 2 2 2 0 Acid Phosphatase DUF3552 PF12072.8 GAM17719.1 - 0.00051 19.5 40.7 0.042 13.3 13.2 3.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3552) DUF4200 PF13863.6 GAM17719.1 - 0.044 14.2 7.7 0.044 14.2 7.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF390 PF04094.14 GAM17719.1 - 0.2 9.9 12.9 0.24 9.6 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF4175 PF13779.6 GAM17719.1 - 0.6 8.0 39.7 0.65 7.8 39.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GREB1 PF15782.5 GAM17719.1 - 1.7 5.7 15.8 2 5.5 15.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer V_ATPase_I PF01496.19 GAM17719.1 - 3.4 5.5 22.1 4.6 5.0 22.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4064 PF13273.6 GAM17720.1 - 0.0041 17.4 2.1 1.6 9.1 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) DUF2434 PF10361.9 GAM17720.1 - 0.13 11.3 5.6 0.15 11.0 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2434) DHHC PF01529.20 GAM17720.1 - 0.38 10.8 3.2 6.3 6.9 0.2 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Ank_4 PF13637.6 GAM17721.1 - 5.4e-35 119.3 5.1 7.8e-05 23.2 0.0 10.7 6 5 4 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM17721.1 - 1.1e-30 105.3 19.7 0.00088 19.5 0.3 13.5 2 1 13 15 15 15 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM17721.1 - 3.4e-30 104.5 16.6 2.7e-06 27.9 0.5 6.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM17721.1 - 1e-12 47.0 3.2 12 6.8 0.0 12.2 10 3 3 13 13 13 1 Ankyrin repeat DUF5049 PF16468.5 GAM17721.1 - 1.4e-06 28.1 1.2 7.7 6.5 0.0 9.4 11 2 4 15 15 15 1 Domain of unknown function (DUF5049) Ank PF00023.30 GAM17721.1 - 0.00025 21.4 7.0 1.2e+02 3.3 0.4 9.7 8 3 0 8 8 8 0 Ankyrin repeat TMEM215 PF15746.5 GAM17721.1 - 0.0054 16.2 0.7 2.7 7.4 0.0 3.6 1 1 1 2 2 2 2 TMEM215 family DUF1707 PF08044.11 GAM17721.1 - 0.018 15.1 0.6 5.9 7.0 0.0 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF1707) Viral_Hsp90 PF03225.14 GAM17721.1 - 0.12 10.9 0.5 6.7 5.1 0.0 3.6 4 1 1 5 5 5 0 Viral heat shock protein Hsp90 homologue Vps53_N PF04100.12 GAM17722.1 - 1.1e-110 370.2 12.2 2e-110 369.4 12.2 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 GAM17722.1 - 1e-14 54.6 7.4 1e-14 54.6 7.4 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 GAM17722.1 - 1.7e-05 25.0 5.3 1.9e-05 24.8 2.7 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG7 PF10191.9 GAM17722.1 - 1.7e-05 23.3 4.6 0.0022 16.3 0.0 3.0 3 0 0 3 3 3 2 Golgi complex component 7 (COG7) COG2 PF06148.11 GAM17722.1 - 0.00014 21.9 4.1 0.0023 18.0 4.2 2.9 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 GAM17722.1 - 0.00031 19.8 8.9 0.00031 19.8 8.9 2.3 2 1 0 2 2 1 1 Spc7 kinetochore protein DUF2884 PF11101.8 GAM17722.1 - 0.0042 16.6 5.9 0.024 14.2 4.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2884) XhlA PF10779.9 GAM17722.1 - 0.019 15.2 4.7 0.019 15.2 4.7 4.9 6 0 0 6 6 6 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 GAM17722.1 - 0.046 13.8 3.9 0.47 10.5 0.7 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Trans_reg_C PF00486.28 GAM17722.1 - 0.089 12.9 0.0 0.4 10.8 0.0 2.2 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Sec34 PF04136.15 GAM17722.1 - 0.26 11.2 7.3 0.035 14.0 1.7 2.5 3 0 0 3 3 3 0 Sec34-like family DUF2730 PF10805.8 GAM17722.1 - 0.36 11.0 3.6 1.4 9.1 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) RasGAP_C PF03836.15 GAM17722.1 - 0.62 10.2 9.0 0.5 10.5 2.7 3.3 2 1 1 3 3 3 0 RasGAP C-terminus DUF948 PF06103.11 GAM17722.1 - 2.7 8.3 4.5 14 6.0 1.7 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Csm1_N PF18504.1 GAM17722.1 - 3.3 8.1 8.3 3.6 8.0 0.1 3.8 2 1 1 3 3 2 0 Csm1 N-terminal domain Striatin PF08232.12 GAM17722.1 - 4 8.0 14.0 0.85 10.2 0.9 2.7 2 0 0 2 2 2 0 Striatin family DnaI_N PF07319.11 GAM17722.1 - 7.5 7.3 7.7 59 4.4 0.1 3.9 3 1 0 3 3 3 0 Primosomal protein DnaI N-terminus Cupin_8 PF13621.6 GAM17723.1 - 6.7e-21 75.2 0.1 8.4e-21 74.8 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 GAM17723.1 - 1.2e-09 38.6 0.0 2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 GAM17723.1 - 0.00069 19.3 0.2 0.00099 18.7 0.2 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 GAM17723.1 - 0.0042 16.8 0.0 0.03 14.0 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 GAM17723.1 - 0.0083 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein GPI PF06560.11 GAM17723.1 - 0.011 15.0 0.4 0.087 12.1 0.0 2.0 1 1 1 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Methyltransf_PK PF05891.12 GAM17724.1 - 4.5e-75 251.9 0.0 5.7e-75 251.6 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 GAM17724.1 - 3e-07 31.0 0.0 5.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM17724.1 - 1.5e-06 28.9 0.0 2.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM17724.1 - 2.3e-06 28.2 0.0 3.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM17724.1 - 0.0005 19.9 0.0 0.00075 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Lig_C PF18330.1 GAM17724.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region WD40 PF00400.32 GAM17725.1 - 2.4e-48 161.1 29.2 5.9e-09 36.4 1.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17725.1 - 1.6e-18 66.8 8.2 0.0019 18.5 0.4 6.0 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 GAM17725.1 - 0.0029 15.7 6.2 0.0038 15.3 1.2 2.4 1 1 1 2 2 2 2 IKI3 family Lactonase PF10282.9 GAM17725.1 - 0.05 12.9 0.0 32 3.6 0.0 3.2 2 1 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Ge1_WD40 PF16529.5 GAM17725.1 - 0.072 12.0 4.9 1.7 7.5 2.6 3.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 GAM17725.1 - 0.49 9.1 3.1 32 3.1 0.1 3.4 3 1 1 4 4 4 0 Nup133 N terminal like DUF2387 PF09526.10 GAM17725.1 - 4.2 7.6 4.8 23 5.2 0.2 3.1 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) Prenyltrans PF00432.21 GAM17726.1 - 5e-27 93.3 8.3 1e-07 31.6 0.1 6.2 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TMEM189_B_dmain PF10520.9 GAM17727.1 - 3e-70 235.8 2.3 3e-70 235.8 2.3 1.8 2 0 0 2 2 2 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 GAM17727.1 - 0.16 12.3 11.5 0.17 12.3 3.9 2.2 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily gag-asp_proteas PF13975.6 GAM17729.1 - 4.1e-08 33.7 0.0 6.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAM17729.1 - 1.5e-07 32.0 0.0 2.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 GAM17729.1 - 0.0006 19.6 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.20 GAM17729.1 - 0.00062 20.0 0.0 0.0019 18.5 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease MG2 PF01835.19 GAM17730.1 - 0.0012 19.2 0.0 0.0069 16.8 0.0 2.4 2 0 0 2 2 2 1 MG2 domain Big_10 PF17964.1 GAM17730.1 - 0.0046 17.0 0.1 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 Bacterial Ig domain Big_5 PF13205.6 GAM17730.1 - 0.0057 17.4 0.0 2.4 8.9 0.0 3.6 3 0 0 3 3 3 1 Bacterial Ig-like domain Adaptin_N PF01602.20 GAM17731.1 - 1.2e-83 281.5 11.0 2.3e-83 280.6 11.0 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 GAM17731.1 - 5.4e-52 175.1 0.5 3.1e-51 172.7 0.2 2.5 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 GAM17731.1 - 5.9e-45 152.6 0.1 1.5e-44 151.3 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 GAM17731.1 - 1.8e-05 24.8 13.5 8.2e-05 22.7 0.0 3.8 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 GAM17731.1 - 0.0011 19.1 0.0 0.0065 16.6 0.0 2.3 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 GAM17731.1 - 0.0034 17.7 0.0 0.21 12.0 0.0 3.4 2 2 1 3 3 3 1 HEAT repeats Glyco_hydro_77 PF02446.17 GAM17731.1 - 0.017 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 4-alpha-glucanotransferase HEAT PF02985.22 GAM17731.1 - 0.018 15.3 0.2 18 5.9 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Nrap_D2 PF17403.2 GAM17731.1 - 0.089 12.6 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain HEAT_EZ PF13513.6 GAM17731.1 - 0.14 12.7 0.0 83 3.8 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat RhoGEF PF00621.20 GAM17732.1 - 1.5e-46 159.0 3.8 5.9e-40 137.4 0.9 2.5 2 0 0 2 2 2 2 RhoGEF domain PH PF00169.29 GAM17732.1 - 0.0097 16.4 0.4 0.099 13.2 0.0 2.8 3 1 0 3 3 3 1 PH domain Ima1_N PF09779.9 GAM17732.1 - 0.16 12.8 0.0 0.16 12.8 0.0 2.9 3 1 0 3 3 3 0 Ima1 N-terminal domain TIG PF01833.24 GAM17733.1 - 1.3e-59 198.3 127.5 3e-08 33.6 3.8 16.6 12 3 4 16 16 16 14 IPT/TIG domain hEGF PF12661.7 GAM17733.1 - 0.0073 16.9 8.6 0.023 15.3 8.6 2.0 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.13 GAM17733.1 - 0.026 14.9 15.3 0.065 13.6 15.3 1.7 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 GAM17733.1 - 0.071 13.4 10.1 0.18 12.1 10.1 1.7 1 0 0 1 1 1 0 EGF-like domain Lectin_C PF00059.21 GAM17733.1 - 0.13 13.0 0.0 0.87 10.3 0.1 2.3 2 0 0 2 2 2 0 Lectin C-type domain SKG6 PF08693.10 GAM17733.1 - 0.27 10.7 4.1 0.83 9.1 4.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF_Tenascin PF18720.1 GAM17733.1 - 2.4 8.3 22.1 0.023 14.7 12.4 2.8 3 0 0 3 3 3 0 Tenascin EGF domain HMG-CoA_red PF00368.18 GAM17734.1 - 3.5e-148 493.5 1.5 4.5e-148 493.1 1.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase IFP_35_N PF07334.13 GAM17734.1 - 0.045 13.8 3.0 1 9.5 0.0 2.4 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ATG13 PF10033.9 GAM17735.1 - 0.0003 20.6 0.4 0.00049 19.9 0.4 1.5 1 1 0 1 1 1 1 Autophagy-related protein 13 RAP1 PF07218.11 GAM17735.1 - 0.13 10.5 5.0 0.17 10.2 5.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PPDFL PF15060.6 GAM17735.1 - 0.5 10.9 6.7 0.22 12.0 3.8 1.9 1 1 0 1 1 1 0 Differentiation and proliferation regulator Mito_fiss_reg PF05308.11 GAM17735.1 - 9 6.3 10.5 12 5.9 9.9 1.5 1 1 0 1 1 1 0 Mitochondrial fission regulator DUF4210 PF13915.6 GAM17736.1 - 1.2e-10 41.8 1.2 3.1e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) FAD_binding_2 PF00890.24 GAM17737.1 - 9.9e-126 420.2 3.0 1.2e-125 419.9 3.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GAM17737.1 - 9.4e-43 145.3 1.9 1.4e-42 144.7 1.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 GAM17737.1 - 3.3e-05 23.2 0.5 0.029 13.6 0.1 2.8 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.22 GAM17737.1 - 8.7e-05 21.8 2.3 0.051 12.6 2.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 GAM17737.1 - 0.00024 20.5 1.4 0.0014 17.9 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM17737.1 - 0.0034 16.7 0.3 0.0053 16.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM17737.1 - 0.038 13.6 1.7 0.087 12.4 1.7 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM17737.1 - 0.084 11.6 0.6 0.19 10.4 0.3 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF4064 PF13273.6 GAM17740.1 - 0.05 13.9 9.5 2.8 8.3 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) SUR7 PF06687.12 GAM17740.1 - 0.12 12.0 16.9 0.029 14.0 7.0 2.2 1 1 0 2 2 2 0 SUR7/PalI family DctQ PF04290.12 GAM17740.1 - 1.5 8.7 13.8 0.28 11.1 5.8 2.5 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component SAP PF02037.27 GAM17742.1 - 9.5e-05 22.1 0.2 0.42 10.4 0.0 3.3 3 0 0 3 3 3 2 SAP domain Rho_N PF07498.12 GAM17742.1 - 0.0042 17.0 0.1 4.5 7.3 0.0 2.9 2 0 0 2 2 2 2 Rho termination factor, N-terminal domain DUF3915 PF13054.6 GAM17742.1 - 0.39 10.7 5.9 0.22 11.5 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) TMIE PF16038.5 GAM17742.1 - 3.1 7.7 6.9 17 5.3 6.9 2.4 1 0 0 1 1 1 0 TMIE protein YL1 PF05764.13 GAM17743.1 - 0.0032 17.6 29.5 0.0032 17.6 29.5 2.0 1 1 1 2 2 2 1 YL1 nuclear protein PsaN PF05479.11 GAM17743.1 - 0.0033 17.6 5.3 0.0054 16.9 5.3 1.3 1 0 0 1 1 1 1 Photosystem I reaction centre subunit N (PSAN or PSI-N) Nop14 PF04147.12 GAM17743.1 - 0.29 9.3 47.8 0.38 8.9 47.8 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GAM17743.1 - 0.6 9.4 41.8 0.82 8.9 41.8 1.2 1 0 0 1 1 1 0 BUD22 Bcl-2_BAD PF10514.9 GAM17743.1 - 0.98 9.9 11.7 2.3 8.7 11.6 1.6 1 1 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD BBS2_Mid PF14783.6 GAM17744.1 - 0.00024 21.1 0.1 0.3 11.1 0.0 3.6 2 2 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 GAM17744.1 - 0.003 17.2 0.0 0.0055 16.3 0.0 1.5 1 1 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 GAM17744.1 - 0.02 15.2 0.3 5.1 7.5 0.3 3.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM17744.1 - 0.073 12.4 0.9 0.37 10.1 0.3 2.2 3 0 0 3 3 3 0 WD40-like domain GNAT_acetyltr_2 PF13718.6 GAM17746.1 - 7.4e-97 323.2 0.0 7.4e-97 323.2 0.0 1.9 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 GAM17746.1 - 1.1e-62 211.0 0.0 4.5e-62 209.0 0.0 2.0 2 0 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.6 GAM17746.1 - 2.3e-44 151.9 12.1 5.5e-28 98.3 3.2 3.0 3 1 1 4 4 4 2 Possible tRNA binding domain DUF1726 PF08351.11 GAM17746.1 - 1.9e-32 111.1 0.1 5.2e-32 109.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 GAM17746.1 - 0.0013 18.5 0.0 2.5 7.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain Acetyltransf_1 PF00583.25 GAM17746.1 - 0.01 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM17746.1 - 0.014 15.8 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain His_Phos_1 PF00300.22 GAM17747.1 - 3e-36 125.0 0.0 1.5e-28 99.9 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) PPR PF01535.20 GAM17748.1 - 2.1e-05 24.4 1.9 31 5.1 0.0 6.0 5 0 0 5 5 5 2 PPR repeat TPR_15 PF13429.6 GAM17748.1 - 0.0076 15.5 0.1 0.035 13.3 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat PPR_2 PF13041.6 GAM17748.1 - 0.012 15.8 6.5 2 8.6 0.0 5.8 6 0 0 6 6 6 0 PPR repeat family zf-C3HC4_3 PF13920.6 GAM17749.1 - 1.3e-11 44.1 8.0 2.1e-11 43.5 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM17749.1 - 3e-10 39.8 10.0 7e-10 38.6 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM17749.1 - 4.8e-09 35.9 11.9 9.1e-09 35.0 11.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM17749.1 - 7e-09 35.9 9.6 1.4e-08 34.9 9.6 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAM17749.1 - 8.4e-09 35.2 7.3 1.9e-08 34.0 7.1 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAM17749.1 - 8.8e-09 35.2 10.1 1.5e-08 34.4 10.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM17749.1 - 2.6e-08 33.8 6.3 1.2e-07 31.7 6.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAM17749.1 - 3.3e-07 30.5 6.3 1.4e-06 28.5 6.3 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 GAM17749.1 - 4.5e-06 26.7 7.4 1.7e-05 24.9 7.7 1.8 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 GAM17749.1 - 0.012 15.2 5.9 0.024 14.3 5.9 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 GAM17749.1 - 0.078 13.0 2.8 0.18 11.9 2.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAM17749.1 - 0.15 11.9 7.8 0.46 10.3 7.8 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 GAM17749.1 - 0.2 11.5 10.4 0.15 11.9 8.2 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zinc-ribbons_6 PF07191.12 GAM17749.1 - 0.33 10.9 6.2 0.72 9.9 6.2 1.6 1 0 0 1 1 1 0 zinc-ribbons zf-RING_6 PF14835.6 GAM17749.1 - 0.92 9.4 6.0 3.3 7.7 6.0 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 GAM17749.1 - 1.5 9.0 14.7 0.51 10.5 4.1 2.9 2 1 1 3 3 3 0 zinc RING finger of MSL2 DZR PF12773.7 GAM17749.1 - 3.4 7.8 8.1 6.3 6.9 8.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.25 GAM17750.1 - 1.1e-44 152.8 0.2 4.5e-32 111.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17750.1 - 5.7e-28 97.9 0.0 2.2e-27 96.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_1 PF00583.25 GAM17750.1 - 4.8e-05 23.6 0.0 9.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM17750.1 - 0.0017 18.7 0.0 0.0035 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM17750.1 - 0.0028 17.6 0.0 0.0095 15.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Kinase-like PF14531.6 GAM17750.1 - 0.022 14.1 0.0 0.085 12.2 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Met_10 PF02475.16 GAM17751.1 - 3.6e-64 216.2 0.0 5.3e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 GAM17751.1 - 2.3e-06 27.3 0.0 5.2e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAM17751.1 - 5.9e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 GAM17751.1 - 9.7e-05 21.7 0.2 0.00042 19.6 0.0 2.0 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.6 GAM17751.1 - 0.0012 19.5 0.0 0.0037 17.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM17751.1 - 0.015 15.1 0.0 0.089 12.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 GAM17751.1 - 0.044 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 GAM17751.1 - 0.077 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ADH_zinc_N PF00107.26 GAM17751.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 GAM17751.1 - 0.18 12.5 0.0 0.58 10.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain SR-25 PF10500.9 GAM17751.1 - 0.36 10.4 11.8 0.49 10.0 11.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LRR_6 PF13516.6 GAM17752.1 - 1.8e-21 74.3 67.0 0.0014 18.5 0.0 15.6 17 0 0 17 17 17 11 Leucine Rich repeat LRR_4 PF12799.7 GAM17752.1 - 0.041 14.3 0.2 0.041 14.3 0.2 11.7 7 3 7 15 15 15 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM17752.1 - 0.11 13.1 33.3 21 6.1 0.5 13.7 15 0 0 15 15 15 0 Leucine Rich Repeat Pkinase PF00069.25 GAM17753.1 - 1.3e-73 247.7 0.0 2.7e-73 246.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17753.1 - 4.9e-36 124.3 0.0 8.5e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM17753.1 - 2.2e-06 27.2 0.0 6.6e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like zf-CCCH PF00642.24 GAM17754.1 - 5.6e-06 26.1 2.0 1.2e-05 25.1 2.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAM17754.1 - 2.2e-05 24.3 4.5 4.6e-05 23.3 4.5 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 GAM17754.1 - 8.7e-05 23.2 1.5 8.7e-05 23.2 1.5 2.7 2 0 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 GAM17754.1 - 0.00015 21.4 1.3 0.00015 21.4 1.3 2.5 3 0 0 3 3 3 1 CCCH-type zinc finger zf-RanBP PF00641.18 GAM17754.1 - 0.00078 18.7 1.1 0.003 16.8 1.1 2.1 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C6H2 PF15801.5 GAM17754.1 - 0.0065 16.8 8.5 0.017 15.4 8.5 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding HGTP_anticodon PF03129.20 GAM17754.1 - 0.03 14.5 0.2 0.088 13.0 0.1 1.9 2 0 0 2 2 2 0 Anticodon binding domain GCV_H PF01597.19 GAM17757.1 - 0.0062 16.4 0.0 0.065 13.1 0.0 2.0 1 1 0 1 1 1 1 Glycine cleavage H-protein URO-D PF01208.17 GAM17758.1 - 5.3e-130 433.6 0.0 5.9e-130 433.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) TPR_12 PF13424.6 GAM17759.1 - 7.4e-06 26.2 4.3 0.19 12.0 1.5 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat DUF4949 PF16307.5 GAM17759.1 - 0.01 15.9 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) SRP_SPB PF02978.19 GAM17759.1 - 0.045 14.4 3.7 0.059 14.0 1.7 2.3 2 0 0 2 2 2 0 Signal peptide binding domain TPR_10 PF13374.6 GAM17759.1 - 0.088 12.7 3.0 16 5.5 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat OSCP PF00213.18 GAM17759.1 - 0.11 12.6 0.5 9 6.4 0.0 3.3 3 0 0 3 3 3 0 ATP synthase delta (OSCP) subunit TPR_2 PF07719.17 GAM17759.1 - 0.16 12.1 2.5 2.9 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM17759.1 - 0.19 11.6 1.4 2.7 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp PF00026.23 GAM17760.1 - 7.9e-115 383.6 2.4 9.3e-115 383.4 2.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM17760.1 - 1.9e-13 51.0 2.8 1.3e-11 45.0 2.8 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAM17760.1 - 0.0023 17.7 0.0 0.0078 16.0 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAM17760.1 - 0.015 15.9 0.0 0.14 12.9 0.0 2.6 3 1 0 3 3 3 0 Aspartyl protease UCH PF00443.29 GAM17761.1 - 1.5e-45 155.7 0.3 1.8e-45 155.4 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM17761.1 - 1e-13 51.6 0.1 1.8e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 GAM17761.1 - 0.0016 17.9 2.6 0.0065 16.0 0.2 2.7 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase ubiquitin PF00240.23 GAM17761.1 - 0.0082 15.9 0.0 0.025 14.3 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Abhydrolase_2 PF02230.16 GAM17762.1 - 3.7e-55 187.1 0.1 4.3e-55 186.9 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAM17762.1 - 1.9e-06 27.4 0.1 0.025 13.8 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 GAM17762.1 - 9.8e-05 22.1 0.1 0.0014 18.3 0.1 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 GAM17762.1 - 0.00071 19.3 0.0 0.0033 17.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM17762.1 - 0.00091 18.8 0.5 1.4 8.4 0.1 2.9 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 GAM17762.1 - 0.0026 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 GAM17762.1 - 0.0026 17.5 0.3 0.0056 16.4 0.3 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 GAM17762.1 - 0.0028 18.3 0.0 0.0033 18.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF443 PF04276.12 GAM17762.1 - 0.02 14.7 1.8 0.032 14.0 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Abhydrolase_3 PF07859.13 GAM17762.1 - 0.032 14.1 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 GAM17762.1 - 0.048 13.2 0.1 0.29 10.6 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2974) Cutinase PF01083.22 GAM17762.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Cutinase Nop16 PF09420.10 GAM17763.1 - 3.3e-11 43.6 13.4 1.5e-08 34.9 1.9 3.8 2 2 1 3 3 3 2 Ribosome biogenesis protein Nop16 DUF4746 PF15928.5 GAM17763.1 - 0.6 9.5 18.1 1.1 8.6 18.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SID-1_RNA_chan PF13965.6 GAM17763.1 - 3.4 6.0 4.6 2.9 6.2 4.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ABC2_membrane_3 PF12698.7 GAM17764.1 - 1.9e-27 96.3 30.6 2.8e-27 95.7 30.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 GAM17764.1 - 3.3e-27 95.7 0.0 8.1e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM17764.1 - 1.2e-11 45.0 0.1 8e-08 32.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 GAM17764.1 - 6.5e-06 25.7 22.2 1.4e-05 24.6 22.2 1.5 1 0 0 1 1 1 1 ABC-2 type transporter SMC_N PF02463.19 GAM17764.1 - 2.5e-05 23.8 0.4 0.0009 18.7 0.1 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAM17764.1 - 0.025 14.5 0.3 0.066 13.1 0.2 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 GAM17764.1 - 0.033 14.6 0.0 0.061 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 GAM17764.1 - 0.17 11.7 0.7 0.75 9.6 0.4 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM17764.1 - 0.24 11.9 1.4 0.32 11.5 0.3 1.8 2 0 0 2 2 2 0 AAA domain DUF3488 PF11992.8 GAM17764.1 - 2.1 7.2 7.3 24 3.7 8.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) DUF2031 PF09592.10 GAM17765.1 - 4.7 6.7 6.1 5.5 6.4 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) N_BRCA1_IG PF16158.5 GAM17766.1 - 0.022 15.5 0.4 0.081 13.7 0.4 1.9 1 0 0 1 1 1 0 Ig-like domain from next to BRCA1 gene Zincin_1 PF06262.11 GAM17766.1 - 0.035 14.2 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase p450 PF00067.22 GAM17767.1 - 2.7e-91 306.6 0.5 3.1e-91 306.5 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.22 GAM17768.1 - 6.1e-182 605.2 0.0 6.9e-182 605.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 GAM17769.1 - 2.9e-181 603.0 0.2 3.2e-181 602.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PDZ_2 PF13180.6 GAM17769.1 - 0.094 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Ank_4 PF13637.6 GAM17771.1 - 9.3e-36 121.8 13.4 3.7e-06 27.4 0.0 8.5 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM17771.1 - 6.4e-35 118.8 14.4 3.8e-05 23.9 0.2 10.9 3 2 9 12 12 12 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM17771.1 - 3.5e-30 104.4 9.6 2.5e-08 34.4 0.0 5.4 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM17771.1 - 3.3e-20 70.0 8.8 2.1 9.2 0.0 12.1 10 1 3 13 13 13 5 Ankyrin repeat DUF5049 PF16468.5 GAM17771.1 - 3.1e-09 36.6 0.1 6.7 6.7 0.0 9.2 8 2 4 12 12 12 2 Domain of unknown function (DUF5049) DUF1707 PF08044.11 GAM17771.1 - 0.0018 18.3 2.3 23 5.1 0.0 5.5 7 0 0 7 7 7 0 Domain of unknown function (DUF1707) Phage_Cox PF10743.9 GAM17771.1 - 0.014 15.5 0.0 4.7 7.4 0.0 3.4 3 0 0 3 3 3 0 Regulatory phage protein cox Tom37 PF10568.9 GAM17771.1 - 0.055 13.8 0.1 78 3.6 0.0 5.0 1 1 4 5 5 5 0 Outer mitochondrial membrane transport complex protein Ank PF00023.30 GAM17771.1 - 0.089 13.3 7.5 2.5e+02 2.4 0.4 8.0 3 3 1 4 4 4 0 Ankyrin repeat RhoGEF PF00621.20 GAM17772.1 - 7.5e-49 166.4 3.1 3.5e-48 164.3 3.1 2.3 1 0 0 1 1 1 1 RhoGEF domain Arm PF00514.23 GAM17772.1 - 2e-18 65.8 12.9 3.8e-05 23.6 0.0 9.2 10 0 0 10 10 10 4 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 GAM17772.1 - 1.3e-07 31.4 20.4 0.023 14.2 0.6 5.3 3 1 1 4 4 4 4 Armadillo-like HEAT_EZ PF13513.6 GAM17772.1 - 0.00085 19.8 2.9 0.3 11.6 0.0 4.5 3 1 1 4 4 4 1 HEAT-like repeat MIR PF02815.19 GAM17773.1 - 1.4e-18 67.4 1.1 1.6e-13 50.9 0.1 2.9 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 GAM17773.1 - 0.00078 18.7 0.3 0.0043 16.3 0.1 2.2 1 1 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Endotoxin_N PF03945.14 GAM17774.1 - 0.00022 21.0 0.1 0.00038 20.2 0.1 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain ParBc_2 PF08857.11 GAM17775.1 - 6.5e-58 195.4 0.2 9e-58 195.0 0.2 1.1 1 0 0 1 1 1 1 Putative ParB-like nuclease Pur_ac_phosph_N PF16656.5 GAM17776.1 - 2.1e-10 41.0 0.1 4.6e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain CUB_2 PF02408.20 GAM17776.1 - 0.0031 17.3 0.2 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 CUB-like domain Metallophos PF00149.28 GAM17776.1 - 0.0041 17.7 0.2 0.0071 16.9 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TauE PF01925.19 GAM17776.1 - 0.013 15.2 5.9 0.02 14.5 5.9 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE U-box PF04564.15 GAM17777.1 - 4e-14 52.6 0.1 9.3e-14 51.4 0.1 1.7 1 0 0 1 1 1 1 U-box domain Tyr-DNA_phospho PF06087.12 GAM17778.1 - 1.5e-13 50.5 0.0 1.7e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 GAM17778.1 - 0.0032 17.4 0.0 0.006 16.5 0.0 1.5 2 0 0 2 2 2 1 PLD-like domain RasGAP PF00616.19 GAM17779.1 - 3.7e-34 118.3 6.1 3.3e-21 76.0 0.0 4.0 4 1 1 5 5 5 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 GAM17779.1 - 2.3e-19 69.9 0.3 2.3e-18 66.7 0.2 2.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain TBK1_CCD1 PF18394.1 GAM17779.1 - 0.0002 21.0 7.4 0.0059 16.2 0.2 3.3 2 0 0 2 2 2 2 TANK-binding kinase 1 coiled-coil domain 1 CRAL_TRIO PF00650.20 GAM17779.1 - 0.0022 17.7 2.9 0.0048 16.6 1.8 2.3 2 0 0 2 2 2 1 CRAL/TRIO domain HEAT PF02985.22 GAM17779.1 - 0.19 12.0 1.6 4.5 7.8 0.1 4.3 3 0 0 3 3 3 0 HEAT repeat FNIP PF05725.12 GAM17780.1 - 8.2e-80 262.8 26.7 1.2e-12 47.8 0.0 10.2 5 2 6 11 11 11 11 FNIP Repeat LRR_4 PF12799.7 GAM17780.1 - 0.15 12.6 0.1 89 3.7 0.0 4.7 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) DUF3827 PF12877.7 GAM17781.1 - 0.0075 14.7 0.1 0.012 14.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) ETRAMP PF09716.10 GAM17781.1 - 0.0099 15.9 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) RNase_PH PF01138.21 GAM17782.1 - 2.4e-20 73.4 0.0 5.2e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAM17782.1 - 7.8e-14 51.5 0.2 1.5e-13 50.5 0.2 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PG_isomerase_N PF18353.1 GAM17782.1 - 0.015 15.6 0.0 0.62 10.5 0.0 2.5 1 1 1 2 2 2 0 Phosphoglucose isomerase N-terminal domain Med31 PF05669.12 GAM17783.1 - 1.2e-36 124.6 15.4 2.3e-36 123.6 15.4 1.5 1 0 0 1 1 1 1 SOH1 eIF_4EBP PF05456.11 GAM17783.1 - 2.7 7.9 13.4 0.074 13.0 2.6 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PRKG1_interact PF15898.5 GAM17783.1 - 9.2 7.2 11.6 13 6.8 8.0 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain CLN5 PF15014.6 GAM17784.1 - 1.3e-17 64.5 8.4 1.8e-17 64.0 8.4 1.2 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 Methyltransf_7 PF03492.15 GAM17784.1 - 0.11 11.7 0.2 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase M16C_assoc PF08367.11 GAM17785.1 - 1.9e-72 243.4 1.4 3.6e-72 242.5 1.4 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 GAM17785.1 - 1.4e-28 100.1 0.0 3.1e-19 69.7 0.1 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAM17785.1 - 3e-08 33.8 0.6 1.3e-07 31.7 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Mit_ribos_Mrp51 PF11709.8 GAM17785.1 - 0.024 14.2 1.3 6.1 6.3 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit Sun2_CC2 PF18580.1 GAM17785.1 - 0.041 14.1 1.4 1.4 9.2 1.2 3.1 3 0 0 3 3 3 0 SUN2 coiled coil domain 2 Imm70 PF15601.6 GAM17785.1 - 0.18 11.3 0.5 0.46 10.0 0.5 1.6 1 0 0 1 1 1 0 Immunity protein 70 Xpo1 PF08389.12 GAM17785.1 - 1.8 8.6 4.4 18 5.4 2.5 2.6 2 0 0 2 2 2 0 Exportin 1-like protein OEP PF02321.18 GAM17786.1 - 0.014 15.2 8.3 0.02 14.7 8.3 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein VKG_Carbox PF05090.14 GAM17787.1 - 1.4e-05 24.2 17.5 2.3e-05 23.4 17.5 1.3 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase SAP PF02037.27 GAM17788.1 - 0.031 14.0 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 SAP domain Sgf11 PF08209.11 GAM17788.1 - 0.07 12.7 0.7 0.18 11.4 0.7 1.7 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zf-C3HC4_3 PF13920.6 GAM17788.1 - 3.6 7.5 7.4 5.9 6.8 1.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 GAM17789.1 - 3.1e-19 69.0 2.9 1.9e-06 28.5 0.0 5.8 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17789.1 - 7.4e-11 42.2 0.0 0.43 10.9 0.0 5.7 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAM17789.1 - 5.3e-06 26.2 0.0 3.6e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 GAM17789.1 - 0.00011 21.2 0.1 0.71 8.8 0.0 3.2 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4106 PF13388.6 GAM17789.1 - 1.3 8.2 7.3 2 7.5 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DEAD PF00270.29 GAM17790.1 - 5.5e-50 169.6 0.0 1.8e-49 167.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM17790.1 - 2.3e-30 105.2 0.5 5.7e-29 100.7 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM17790.1 - 8.4e-05 22.6 0.0 0.00032 20.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAM17790.1 - 0.013 14.7 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SapB_2 PF03489.17 GAM17791.1 - 0.00015 21.8 0.4 0.00015 21.8 0.4 2.4 3 0 0 3 3 3 1 Saposin-like type B, region 2 Lipase_GDSL_2 PF13472.6 GAM17791.1 - 0.00069 20.1 0.6 0.0017 18.8 0.6 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cu-binding_MopE PF11617.8 GAM17791.1 - 0.39 10.9 3.3 3.4 7.9 3.3 2.6 1 1 0 1 1 1 0 Putative metal-binding motif Ank_2 PF12796.7 GAM17792.1 - 9.1e-34 115.9 10.9 2.2e-07 31.4 0.2 6.1 3 3 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM17792.1 - 3.1e-29 101.0 9.3 0.00065 20.2 0.2 8.8 6 1 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM17792.1 - 1.1e-22 77.7 5.4 1.1 10.0 0.0 12.8 13 0 0 13 13 13 5 Ankyrin repeat Ank_5 PF13857.6 GAM17792.1 - 1.7e-17 63.2 16.4 0.087 13.2 0.0 11.4 2 2 10 12 12 12 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM17792.1 - 5.7e-08 32.9 4.0 7.4 7.2 0.1 9.3 7 2 2 9 9 9 1 Ankyrin repeat DUF3447 PF11929.8 GAM17792.1 - 0.0011 18.9 3.8 2 8.4 0.0 5.2 4 2 1 5 5 5 1 Domain of unknown function (DUF3447) DUF5049 PF16468.5 GAM17792.1 - 0.0082 16.0 0.3 17 5.4 0.0 4.9 3 1 2 5 5 5 1 Domain of unknown function (DUF5049) RasGEF PF00617.19 GAM17793.1 - 1.3e-55 188.4 0.2 3.2e-55 187.1 0.2 1.7 1 0 0 1 1 1 1 RasGEF domain RCC1 PF00415.18 GAM17793.1 - 5.8e-48 161.3 18.8 2e-12 47.5 0.1 8.0 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM17793.1 - 9.9e-36 120.8 17.6 3.8e-10 39.3 1.7 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RasGEF_N PF00618.20 GAM17793.1 - 8.1e-17 61.4 4.2 2.5e-16 59.8 0.8 3.1 2 1 0 2 2 2 1 RasGEF N-terminal motif RhoGEF PF00621.20 GAM17793.1 - 4.7e-15 56.3 1.7 2.4e-13 50.7 0.9 2.7 2 0 0 2 2 2 1 RhoGEF domain SPX PF03105.19 GAM17793.1 - 0.022 14.7 0.6 0.022 14.7 0.6 2.2 2 0 0 2 2 2 0 SPX domain Hira PF07569.11 GAM17793.1 - 0.19 11.4 2.6 2.5 7.7 0.0 3.3 4 0 0 4 4 4 0 TUP1-like enhancer of split Pkinase_Tyr PF07714.17 GAM17794.1 - 5.5e-60 202.8 0.0 1.1e-59 201.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM17794.1 - 1.4e-53 182.0 0.1 5.7e-53 180.0 0.1 2.1 1 0 0 1 1 1 1 Protein kinase domain SUIM_assoc PF16619.5 GAM17794.1 - 0.0057 16.7 6.4 0.014 15.4 1.0 3.2 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Kinase-like PF14531.6 GAM17794.1 - 0.026 13.8 0.0 0.056 12.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF2192 PF09958.9 GAM17794.1 - 0.081 12.4 1.9 0.21 11.1 1.9 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) Kdo PF06293.14 GAM17794.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MORN PF02493.20 GAM17794.1 - 1.5 8.9 4.8 21 5.2 0.1 3.7 4 0 0 4 4 4 0 MORN repeat Sin3a_C PF16879.5 GAM17795.1 - 3.1e-60 204.3 3.7 3.1e-60 204.3 3.7 6.6 6 2 2 8 8 8 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 GAM17795.1 - 8.5e-39 131.6 0.5 5.6e-38 128.9 0.0 2.8 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 GAM17795.1 - 4e-34 116.5 12.3 3.3e-17 62.3 4.5 5.7 5 1 0 5 5 5 3 Paired amphipathic helix repeat COX5A PF02284.16 GAM17795.1 - 0.0057 16.6 0.8 7.7 6.6 0.0 3.2 2 0 0 2 2 2 2 Cytochrome c oxidase subunit Va ORC4_C PF14629.6 GAM17796.1 - 1.1e-12 47.9 4.3 1.1e-12 47.9 4.3 1.5 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 GAM17796.1 - 1.6e-11 44.9 0.0 7.9e-10 39.4 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 GAM17796.1 - 1.2e-07 31.9 0.1 2.5e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 GAM17796.1 - 4.9e-07 30.2 0.0 1.1e-06 29.1 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM17796.1 - 4.3e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAM17796.1 - 0.00013 21.9 0.2 0.0008 19.4 0.0 2.3 2 1 0 2 2 2 1 NACHT domain TniB PF05621.11 GAM17796.1 - 0.00037 19.9 0.2 0.41 10.0 0.2 2.6 2 1 1 3 3 3 2 Bacterial TniB protein AAA_7 PF12775.7 GAM17796.1 - 0.003 17.1 6.4 0.48 9.9 0.0 4.1 4 1 0 4 4 4 1 P-loop containing dynein motor region T2SSE PF00437.20 GAM17796.1 - 0.0047 16.0 0.0 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.6 GAM17796.1 - 0.011 15.7 0.0 0.053 13.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 GAM17796.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 GAM17796.1 - 0.019 14.2 0.0 0.047 12.9 0.0 1.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 GAM17796.1 - 0.022 14.9 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAM17796.1 - 0.049 14.0 0.1 0.15 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAM17796.1 - 0.052 13.8 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 GAM17796.1 - 0.14 11.9 1.7 2.7 7.7 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 GAM17796.1 - 0.16 11.9 0.0 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 NTPase Ras PF00071.22 GAM17797.1 - 4.3e-42 143.5 0.1 5.1e-42 143.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM17797.1 - 6.1e-30 103.9 0.1 8.8e-30 103.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM17797.1 - 6e-18 64.9 0.0 9.1e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM17797.1 - 5.7e-07 29.6 0.0 9.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAM17797.1 - 2.7e-06 26.9 0.0 3.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM17797.1 - 0.00023 20.7 0.1 0.0016 18.0 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 GAM17797.1 - 0.0006 19.6 0.0 0.0021 17.8 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 GAM17797.1 - 0.0028 17.1 0.1 0.005 16.3 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit TniB PF05621.11 GAM17797.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 GAM17797.1 - 0.012 15.4 0.1 0.055 13.2 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 GAM17797.1 - 0.034 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 GAM17797.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin DUF1998 PF09369.10 GAM17797.1 - 0.11 13.3 0.0 0.29 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1998) G-alpha PF00503.20 GAM17797.1 - 0.15 11.2 1.1 1.9 7.6 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit HECT PF00632.25 GAM17800.1 - 1.1e-91 307.6 1.4 1.3e-91 307.3 0.2 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 GAM17800.1 - 8.4e-11 41.9 2.8 1.6e-10 41.0 2.8 1.5 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Suf PF05843.14 GAM17801.1 - 1.1e-10 42.1 39.0 1.6e-07 31.6 0.6 5.3 2 1 3 5 5 5 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 GAM17801.1 - 0.042 14.4 0.0 25 5.5 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM17801.1 - 0.07 13.8 0.0 0.56 11.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM17801.1 - 0.19 12.6 0.0 22 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PI3K_1B_p101 PF10486.9 GAM17801.1 - 5.4 4.7 15.7 0.01 13.6 2.0 2.1 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DDHD PF02862.17 GAM17801.1 - 5.7 7.0 9.4 24 5.0 4.2 2.4 2 0 0 2 2 2 0 DDHD domain CBM49 PF09478.10 GAM17802.1 - 8.7e-17 61.2 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 NIF PF03031.18 GAM17803.1 - 6.6e-52 175.4 2.6 1.1e-51 174.7 2.6 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 GAM17803.1 - 0.13 12.6 0.0 1.4 9.3 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase SPATA3 PF15662.5 GAM17803.1 - 0.29 11.7 5.9 0.54 10.9 5.9 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF4179 PF13786.6 GAM17804.1 - 0.83 10.2 4.0 5.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) RIFIN PF02009.16 GAM17804.1 - 1.6 8.6 3.6 2.6 7.8 3.6 1.3 1 0 0 1 1 1 0 Rifin CCDC84 PF14968.6 GAM17804.1 - 2.8 7.5 4.7 4.6 6.8 4.7 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 zf-ANAPC11 PF12861.7 GAM17805.1 - 2.8e-35 120.2 17.2 3.1e-35 120.1 17.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 GAM17805.1 - 1.1e-22 80.1 19.1 1.5e-22 79.6 19.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAM17805.1 - 4.3e-06 27.0 21.6 7.1e-05 23.1 21.6 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAM17805.1 - 0.0016 18.4 10.2 0.0042 17.1 10.4 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAM17805.1 - 0.0053 16.6 20.1 0.0063 16.4 18.0 2.2 1 1 1 2 2 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 GAM17805.1 - 0.018 15.1 8.2 0.018 15.1 8.2 2.3 2 1 0 2 2 2 0 RING-variant domain zf-C3HC4_2 PF13923.6 GAM17805.1 - 0.028 14.3 15.5 0.028 14.3 15.5 2.4 1 1 1 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM17805.1 - 0.039 13.9 18.2 0.43 10.6 18.7 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.8 GAM17805.1 - 0.066 13.0 7.4 0.13 12.1 7.4 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H_2 PF13832.6 GAM17805.1 - 1.1 9.4 14.5 3.5 7.8 14.5 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.8 GAM17805.1 - 1.4 9.1 16.5 7.9 6.7 16.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Pkinase_Tyr PF07714.17 GAM17806.1 - 3.4e-36 124.9 0.0 5.3e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM17806.1 - 9.2e-29 100.6 0.0 1.7e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 GAM17806.1 - 8.2e-08 32.0 5.4 7.7e-05 22.6 0.1 5.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAM17806.1 - 0.0008 19.7 0.0 1.6 9.1 0.0 3.9 2 2 2 4 4 4 1 HEAT repeats Atx10homo_assoc PF09759.9 GAM17806.1 - 0.0035 17.3 9.3 0.0081 16.2 0.4 4.4 4 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 GAM17806.1 - 0.03 14.6 0.3 4.8 7.7 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat RTP1_C1 PF10363.9 GAM17806.1 - 1.1 9.5 3.5 16 5.7 0.1 3.7 4 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Acetyltransf_3 PF13302.7 GAM17807.1 - 4.7e-17 63.0 0.0 5.3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM17807.1 - 8.8e-06 25.9 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAM17807.1 - 0.068 13.1 0.0 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein GNAT_acetyltran PF12746.7 GAM17807.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_7 PF13508.7 GAM17807.1 - 0.092 13.2 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Snf7 PF03357.21 GAM17808.1 - 9.5e-38 129.5 17.2 1.2e-37 129.2 17.2 1.1 1 0 0 1 1 1 1 Snf7 B5 PF03484.15 GAM17808.1 - 0.014 15.7 1.2 4.3 7.7 0.2 2.6 1 1 1 2 2 2 0 tRNA synthetase B5 domain DUF3091 PF11291.8 GAM17808.1 - 0.15 12.3 7.3 0.31 11.3 5.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3091) SYF2 PF08231.12 GAM17808.1 - 0.21 12.0 6.1 0.34 11.3 6.1 1.3 1 0 0 1 1 1 0 SYF2 splicing factor DUF5082 PF16888.5 GAM17808.1 - 0.24 11.7 9.8 0.11 12.8 6.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF948 PF06103.11 GAM17808.1 - 5.3 7.4 8.9 2.7 8.3 1.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) RWP-RK PF02042.15 GAM17810.1 - 0.0007 19.5 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 GAM17810.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family CorA PF01544.18 GAM17811.1 - 5.8e-09 35.7 2.0 5.8e-09 35.7 2.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2721 PF11026.8 GAM17811.1 - 0.011 15.6 0.1 0.011 15.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) TFIIA PF03153.13 GAM17811.1 - 1.1 9.1 19.7 2.3 8.1 19.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3818 PF12825.7 GAM17812.1 - 8.4e-19 67.8 5.5 1.5e-12 47.3 1.4 4.1 3 1 0 4 4 4 2 Domain of unknown function in PX-proteins (DUF3818) Otopetrin PF03189.13 GAM17812.1 - 0.62 8.8 4.2 1.5 7.5 4.2 1.7 1 0 0 1 1 1 0 Otopetrin DUF3439 PF11921.8 GAM17812.1 - 0.78 9.7 18.2 0.069 13.1 10.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) zf-C3Hc3H PF13891.6 GAM17813.1 - 4.6e-10 39.7 7.3 8.2e-10 38.9 7.3 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain zf-primase PF09329.11 GAM17813.1 - 6.7e-05 22.6 0.4 6.7e-05 22.6 0.4 2.9 4 1 0 4 4 4 1 Primase zinc finger zf-TRM13_CCCH PF11722.8 GAM17813.1 - 0.1 12.4 10.7 0.078 12.8 3.5 2.7 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein SAPS PF04499.15 GAM17813.1 - 4.9 5.8 23.3 0.37 9.5 4.1 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 GAM17813.1 - 5.5 5.2 40.4 0.091 11.0 10.8 2.2 2 0 0 2 2 2 0 CDC45-like protein Pro_isomerase PF00160.21 GAM17814.1 - 5.2e-47 160.0 0.1 6e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M24 PF00557.24 GAM17815.1 - 8.7e-49 166.0 0.0 1.2e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4201 PF13870.6 GAM17816.1 - 6.5e-07 29.3 7.6 6.5e-07 29.3 7.6 9.2 2 1 5 7 7 5 2 Domain of unknown function (DUF4201) HOOK PF05622.12 GAM17816.1 - 1.2e-05 23.8 53.8 0.00014 20.2 29.9 6.9 2 1 2 5 5 4 2 HOOK protein DUF724 PF05266.14 GAM17816.1 - 7.6e-05 22.6 6.9 7.6e-05 22.6 6.9 9.3 2 2 7 9 9 8 2 Protein of unknown function (DUF724) Filament PF00038.21 GAM17816.1 - 0.00017 21.3 21.5 0.00074 19.2 3.6 7.9 2 1 4 7 7 6 3 Intermediate filament protein Fez1 PF06818.15 GAM17816.1 - 0.00028 21.4 15.0 0.00028 21.4 15.0 7.4 1 1 7 8 8 7 3 Fez1 ATG16 PF08614.11 GAM17816.1 - 0.00073 19.8 49.2 0.0029 17.9 18.3 9.3 1 1 4 6 6 5 3 Autophagy protein 16 (ATG16) Spc7 PF08317.11 GAM17816.1 - 0.00084 18.3 8.6 0.00084 18.3 8.6 8.8 2 2 7 9 9 7 5 Spc7 kinetochore protein APG6_N PF17675.1 GAM17816.1 - 0.00089 19.8 13.8 0.0014 19.1 5.3 10.3 3 1 6 10 10 8 3 Apg6 coiled-coil region Golgin_A5 PF09787.9 GAM17816.1 - 0.0012 18.4 28.9 0.0012 18.4 28.9 6.4 1 1 4 6 6 6 2 Golgin subfamily A member 5 Phage_GP20 PF06810.11 GAM17816.1 - 0.0029 17.4 18.4 0.0069 16.2 6.6 11.4 3 1 8 11 11 8 4 Phage minor structural protein GP20 HAP1_N PF04849.13 GAM17816.1 - 0.0031 16.8 9.8 0.0031 16.8 9.8 7.4 2 1 3 6 6 5 2 HAP1 N-terminal conserved region GIT_CC PF16559.5 GAM17816.1 - 0.0038 17.1 1.3 0.0038 17.1 1.3 10.6 8 2 5 13 13 12 2 GIT coiled-coil Rho guanine nucleotide exchange factor GAS PF13851.6 GAM17816.1 - 0.0057 16.0 22.2 0.0057 16.0 22.2 7.6 2 1 4 7 7 7 1 Growth-arrest specific micro-tubule binding PKcGMP_CC PF16808.5 GAM17816.1 - 0.018 14.9 0.2 0.1 12.5 0.1 14.4 17 0 0 17 17 17 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Shugoshin_N PF07558.11 GAM17816.1 - 0.072 13.0 6.2 1.6 8.7 0.2 4.3 3 0 0 3 3 2 0 Shugoshin N-terminal coiled-coil region DUF3567 PF12091.8 GAM17816.1 - 0.12 12.5 3.4 6 7.1 0.2 3.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) DUF3911 PF13050.6 GAM17816.1 - 1.3 9.2 6.8 0.31 11.2 0.5 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) NRDE-2 PF08424.10 GAM17817.1 - 4.3e-80 269.2 5.0 4.3e-80 269.2 5.0 3.2 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 GAM17817.1 - 3.2e-11 43.1 3.6 0.0079 16.9 0.2 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat HRDC PF00570.23 GAM17817.1 - 6.5e-05 22.9 0.1 0.00033 20.6 0.0 2.2 2 0 0 2 2 2 1 HRDC domain TPR_15 PF13429.6 GAM17817.1 - 0.001 18.3 3.3 0.011 15.0 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM17817.1 - 0.0019 18.7 3.0 41 4.8 0.2 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3292 PF11696.8 GAM17817.1 - 0.066 11.6 2.1 0.1 10.9 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TPR_2 PF07719.17 GAM17817.1 - 0.15 12.2 0.1 5.1 7.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.9 GAM17817.1 - 0.93 9.1 12.5 2.6 7.6 12.5 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med19 PF10278.9 GAM17817.1 - 1.4 8.9 8.8 4 7.3 8.8 1.7 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 COX16 PF14138.6 GAM17818.1 - 3.1e-09 37.2 0.1 1.9e-08 34.7 0.1 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 dCMP_cyt_deam_1 PF00383.23 GAM17819.1 - 5.1e-15 55.2 0.2 8.9e-15 54.4 0.2 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAM17819.1 - 5.8e-08 32.6 0.1 9.9e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 GAM17819.1 - 0.0013 18.8 1.2 0.13 12.3 0.0 2.8 2 1 1 3 3 3 2 Bd3614-like deaminase Gelsolin PF00626.22 GAM17820.1 - 3.3e-21 75.0 0.0 7.3e-08 32.2 0.0 11.1 12 1 0 13 13 13 5 Gelsolin repeat VHP PF02209.19 GAM17820.1 - 2.5e-14 53.1 0.4 7.1e-14 51.6 0.4 1.9 1 0 0 1 1 1 1 Villin headpiece domain SpoU_methylase PF00588.19 GAM17820.1 - 0.5 10.5 0.0 0.5 10.5 0.0 3.3 2 1 0 2 2 2 0 SpoU rRNA Methylase family FtsX PF02687.21 GAM17821.1 - 0.01 16.3 0.2 0.01 16.3 0.2 3.1 1 1 1 2 2 2 0 FtsX-like permease family DUF2207 PF09972.9 GAM17821.1 - 7.6 5.2 9.6 25 3.4 7.1 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PI3Ka PF00613.20 GAM17822.1 - 1.7e-50 171.0 1.5 1.7e-50 171.0 1.5 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 GAM17822.1 - 4.7e-41 141.3 1.7 9.1e-40 137.0 0.1 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 GAM17822.1 - 1.9e-09 37.6 0.2 5.1e-09 36.2 0.2 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 GAM17822.1 - 5.7e-07 29.7 0.4 2.3e-06 27.7 0.3 2.1 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 GAM17822.1 - 0.00079 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) FlxA PF14282.6 GAM17822.1 - 0.091 12.8 12.6 0.015 15.2 6.3 2.8 2 0 0 2 2 2 0 FlxA-like protein DUF724 PF05266.14 GAM17822.1 - 0.27 11.0 4.8 0.69 9.7 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IL2 PF00715.17 GAM17822.1 - 0.49 10.3 7.1 1.2 9.0 1.3 3.0 3 0 0 3 3 3 0 Interleukin 2 FAM76 PF16046.5 GAM17822.1 - 0.51 9.6 9.0 1.2 8.4 9.0 1.5 1 0 0 1 1 1 0 FAM76 protein adh_short PF00106.25 GAM17823.1 - 4.3e-10 39.4 0.0 3.5e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAM17823.1 - 2.8e-05 24.1 0.1 0.00025 21.0 0.0 2.1 2 0 0 2 2 2 1 KR domain Peptidase_C80 PF11713.8 GAM17823.1 - 0.043 14.1 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase C80 family Helicase_C_2 PF13307.6 GAM17823.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain WD40 PF00400.32 GAM17824.1 - 3.8e-58 192.1 16.4 2.1e-10 41.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17824.1 - 2.6e-24 85.3 0.9 2.2e-08 34.3 0.0 5.5 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM17824.1 - 3.3e-14 53.2 0.2 5.4e-06 26.4 0.1 4.1 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAM17824.1 - 2.9e-10 39.4 2.6 0.19 10.3 0.1 5.1 2 1 3 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAM17824.1 - 4.8e-10 38.9 1.1 0.0029 16.6 0.1 4.8 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAM17824.1 - 5.5e-07 28.5 0.1 0.015 13.9 0.1 3.9 1 1 2 4 4 4 2 Cytochrome D1 heme domain Frtz PF11768.8 GAM17824.1 - 6.9e-07 28.0 0.1 1.4e-05 23.7 0.0 2.4 2 1 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 GAM17824.1 - 3.6e-06 26.5 0.3 0.0093 15.3 0.1 3.7 3 1 1 4 4 4 1 WD40-like domain PQQ_2 PF13360.6 GAM17824.1 - 0.00019 21.1 0.0 0.0068 16.0 0.0 2.8 2 1 0 2 2 2 1 PQQ-like domain PALB2_WD40 PF16756.5 GAM17824.1 - 0.00044 19.3 1.2 0.25 10.2 0.1 3.7 1 1 2 4 4 4 2 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 GAM17824.1 - 0.00052 19.9 1.3 5.6 7.0 0.2 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Utp8 PF10395.9 GAM17824.1 - 0.01 14.4 0.3 0.11 10.9 0.1 2.2 3 0 0 3 3 3 0 Utp8 family Coatomer_WDAD PF04053.14 GAM17824.1 - 0.015 14.4 0.8 0.14 11.2 0.3 2.6 1 1 0 2 2 2 0 Coatomer WD associated region Vac_Fusion PF02346.16 GAM17824.1 - 0.1 12.3 0.0 0.7 9.6 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 IKI3 PF04762.12 GAM17824.1 - 0.14 10.1 0.1 0.16 9.9 0.1 1.3 1 0 0 1 1 1 0 IKI3 family DUF1513 PF07433.11 GAM17824.1 - 0.16 11.0 0.0 16 4.4 0.0 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1513) SUKH_6 PF14568.6 GAM17824.1 - 0.2 12.1 0.9 3.6 8.0 0.1 3.1 1 1 3 4 4 4 0 SMI1-KNR4 cell-wall CAP_N PF01213.19 GAM17825.1 - 0.54 9.7 13.2 0.86 9.0 13.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GAM17825.1 - 0.58 10.2 17.4 0.92 9.6 17.4 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 GAM17825.1 - 0.63 10.1 12.4 0.93 9.5 12.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Herpes_pp85 PF04637.12 GAM17825.1 - 3.6 5.9 6.3 3.6 5.9 6.3 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) zf-4CXXC_R1 PF10497.9 GAM17826.1 - 8.6e-10 38.7 16.0 1.8e-09 37.7 16.0 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PEHE PF15275.6 GAM17826.1 - 0.00086 19.9 0.9 0.00086 19.9 0.9 3.2 3 2 0 3 3 3 1 PEHE domain SdrD_B PF17210.3 GAM17827.1 - 1.1e-20 73.9 9.4 3.1e-08 33.8 0.1 15.2 9 1 8 17 17 17 6 SdrD B-like domain DDE_1 PF03184.19 GAM17828.1 - 1.8e-11 44.0 0.2 2.7e-11 43.4 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 GAM17828.1 - 0.033 13.9 0.1 0.17 11.6 0.1 1.9 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 GAM17829.1 - 7.8e-06 25.8 0.1 2.2e-05 24.4 0.1 1.8 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain Transglut_core2 PF13369.6 GAM17829.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily NAGLU_C PF12972.7 GAM17830.1 - 0.067 12.7 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Beta_helix PF13229.6 GAM17831.1 - 4.1e-14 52.7 39.9 4e-10 39.8 11.1 3.8 2 1 2 4 4 4 3 Right handed beta helix region NosD PF05048.13 GAM17831.1 - 2.9e-07 30.0 19.6 4.6e-06 26.1 3.0 3.3 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) TALPID3 PF15324.6 GAM17831.1 - 0.6 7.7 4.3 0.84 7.2 4.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Transferase PF02458.15 GAM17832.1 - 1.5e-21 76.6 0.0 8.8e-21 74.0 0.0 2.1 1 1 0 1 1 1 1 Transferase family UDPGP PF01704.18 GAM17833.1 - 9.9e-156 518.5 3.2 1.1e-155 518.3 3.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Dynein_AAA_lid PF17852.1 GAM17834.1 - 0.0021 18.1 0.1 0.0021 18.1 0.1 2.5 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain BTB_2 PF02214.22 GAM17835.1 - 4e-17 62.4 1.1 6.8e-17 61.6 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 GAM17835.1 - 0.00017 21.7 0.0 0.0004 20.5 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain SUIM_assoc PF16619.5 GAM17835.1 - 0.0004 20.4 18.8 3.3 7.9 0.0 4.2 3 2 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Metallothio_Euk PF12749.7 GAM17835.1 - 0.014 15.5 1.4 0.014 15.5 1.4 1.6 2 0 0 2 2 2 0 Eukaryotic metallothionein BTB PF00651.31 GAM17835.1 - 0.025 14.8 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain CTU2 PF10288.9 GAM17835.1 - 0.13 12.5 20.8 0.026 14.8 7.1 2.3 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 MGC-24 PF05283.11 GAM17835.1 - 2.2 8.7 13.4 1.8 9.0 2.8 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HpaB_N PF11794.8 GAM17835.1 - 3.8 7.1 7.3 3.4 7.3 1.7 2.2 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Ureide_permease PF07168.11 GAM17835.1 - 4.4 6.0 8.3 0.1 11.4 0.6 1.9 2 0 0 2 2 2 0 Ureide permease Presenilin PF01080.17 GAM17835.1 - 8.5 5.0 16.9 2.6 6.7 6.0 2.1 2 0 0 2 2 2 0 Presenilin Myosin_head PF00063.21 GAM17836.1 - 1.5e-266 886.0 0.0 2e-266 885.6 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAM17836.1 - 1.3e-43 148.9 3.5 2.3e-43 148.1 3.5 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 GAM17836.1 - 4.3e-19 67.9 0.7 8.8e-19 66.9 0.7 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM17836.1 - 2e-18 66.0 0.1 4.8e-18 64.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM17836.1 - 1.6e-16 59.7 0.0 3.3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 GAM17836.1 - 0.0014 19.1 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 GAM17836.1 - 0.008 15.5 0.1 0.018 14.3 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 GAM17836.1 - 0.015 15.5 0.0 0.071 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAM17836.1 - 0.029 13.6 0.0 0.058 12.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 GAM17836.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.9 GAM17836.1 - 0.069 12.1 0.0 0.17 10.7 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 GAM17836.1 - 0.11 12.9 0.1 0.62 10.5 0.1 2.3 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 GAM17836.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 GAM17836.1 - 0.4 11.2 1.7 0.97 9.9 0.0 2.4 2 1 0 2 2 2 0 ABC transporter PNK3P PF08645.11 GAM17837.1 - 9.3e-50 168.5 0.0 1.4e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 GAM17837.1 - 8.8e-16 58.4 0.5 3.7e-13 49.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 GAM17837.1 - 1.9e-05 24.3 1.1 0.1 12.0 0.0 2.6 3 0 0 3 3 3 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 GAM17837.1 - 0.00096 18.5 0.6 0.2 10.9 0.0 2.9 4 0 0 4 4 4 1 Zeta toxin BSP_II PF05432.11 GAM17837.1 - 0.018 14.8 21.7 0.027 14.2 21.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pox_Ag35 PF03286.14 GAM17837.1 - 0.022 14.5 17.5 0.037 13.8 17.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Hydrolase_like PF13242.6 GAM17837.1 - 0.049 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 HAD-hyrolase-like RGS12_us1 PF16613.5 GAM17837.1 - 0.85 10.0 4.6 1.7 8.9 4.3 1.6 1 1 0 1 1 1 0 Unstructured region of RGS12 MCM_bind PF09739.9 GAM17837.1 - 1.1 7.7 9.8 1.7 7.0 9.8 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Nop14 PF04147.12 GAM17837.1 - 1.2 7.3 15.1 1.5 6.9 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 GAM17837.1 - 3.2 6.6 8.0 5.3 5.9 8.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 GAM17837.1 - 3.8 5.7 14.4 5.2 5.2 14.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAM17837.1 - 4.7 5.2 11.8 6.5 4.7 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sec62 PF03839.16 GAM17837.1 - 5.6 6.4 6.2 8.7 5.8 6.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 SWI-SNF_Ssr4 PF08549.10 GAM17837.1 - 6.8 5.2 18.2 8.8 4.8 18.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SWIRM-assoc_2 PF16496.5 GAM17837.1 - 9.9 4.9 18.3 14 4.4 18.3 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Cyclin_N PF00134.23 GAM17838.1 - 3e-20 72.2 0.4 4.2e-17 62.1 0.3 2.8 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAM17838.1 - 0.00034 20.7 0.4 0.00034 20.7 0.4 3.6 4 1 0 4 4 4 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 GAM17838.1 - 0.047 14.1 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Cyclin C-terminal domain SpoIIIAH PF12685.7 GAM17838.1 - 0.41 10.5 13.6 0.042 13.7 5.6 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein CMV_1a PF12467.8 GAM17838.1 - 1.4 9.2 6.3 2.9 8.2 6.3 1.5 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family SOG2 PF10428.9 GAM17838.1 - 4.1 6.5 45.1 1.1 8.4 34.0 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein Patatin PF01734.22 GAM17839.1 - 1e-13 51.9 1.2 9.9e-06 25.9 0.1 2.1 1 1 1 2 2 2 2 Patatin-like phospholipase DUF846 PF05832.12 GAM17840.1 - 1.2e-51 174.4 16.9 1.4e-51 174.2 16.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DcuC PF03606.15 GAM17840.1 - 0.0016 17.0 0.6 0.0021 16.6 0.4 1.2 1 1 0 1 1 1 1 C4-dicarboxylate anaerobic carrier NAT PF04768.13 GAM17840.1 - 0.019 14.6 1.9 0.032 13.9 1.9 1.2 1 0 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase DUF3430 PF11912.8 GAM17842.1 - 2.1e-20 73.7 9.1 2.9e-20 73.2 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF2828 PF11443.8 GAM17843.1 - 5.8e-124 414.5 0.5 6e-98 328.6 0.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) bZIP_2 PF07716.15 GAM17843.1 - 6.7 6.9 8.1 0.44 10.7 1.7 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Cyclin PF08613.11 GAM17844.1 - 5.6e-31 108.1 0.2 6.9e-31 107.8 0.2 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAM17844.1 - 1.2e-11 44.4 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Amidohydro_1 PF01979.20 GAM17846.1 - 5.1e-34 118.1 0.4 8.2e-34 117.4 0.4 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM17846.1 - 4.3e-15 56.1 3.5 2.6e-07 30.5 0.0 2.8 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 GAM17846.1 - 9.9e-06 25.5 0.1 1.4e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Motile_Sperm PF00635.26 GAM17846.1 - 0.1 12.4 0.2 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 MSP (Major sperm protein) domain AP_endonuc_2 PF01261.24 GAM17846.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DnaJ PF00226.31 GAM17847.1 - 1.1e-18 67.0 4.8 1.4e-18 66.7 1.1 2.3 2 0 0 2 2 2 1 DnaJ domain Acetyltransf_11 PF13720.6 GAM17847.1 - 0.13 12.8 1.0 45 4.6 0.0 3.2 3 1 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Talin_middle PF09141.10 GAM17847.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Talin, middle domain SapB_1 PF05184.15 GAM17847.1 - 0.69 10.0 6.0 3.6 7.7 0.1 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 1 Myotub-related PF06602.14 GAM17849.1 - 5.4e-140 466.3 0.0 8.7e-140 465.6 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FERM_f0 PF16511.5 GAM17849.1 - 4.1e-20 71.9 7.7 2.1e-08 34.4 0.2 4.1 4 0 0 4 4 4 2 N-terminal or F0 domain of Talin-head FERM PI3K_rbd PF00794.18 GAM17849.1 - 0.00061 19.9 1.5 0.72 10.0 0.0 3.5 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain GRAM PF02893.20 GAM17849.1 - 0.00065 19.6 0.1 0.0022 17.9 0.1 1.9 1 0 0 1 1 1 1 GRAM domain DSPc PF00782.20 GAM17849.1 - 0.0022 17.8 0.0 0.0059 16.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM17849.1 - 0.0057 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FERM_N PF09379.10 GAM17849.1 - 0.044 13.7 0.1 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 FERM N-terminal domain GIT_CC PF16559.5 GAM17849.1 - 0.11 12.4 0.6 0.28 11.1 0.6 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CCDC92 PF14916.6 GAM17849.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Solute_trans_a PF03619.16 GAM17850.1 - 1.7e-98 329.3 28.5 2e-98 329.1 28.5 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Pallilysin PF18663.1 GAM17851.1 - 0.052 13.5 6.6 0.78 9.7 0.1 2.7 2 0 0 2 2 2 0 Pallilysin beta barrel domain Kinesin PF00225.23 GAM17852.1 - 1.2e-75 254.5 0.1 1.2e-75 254.5 0.1 3.1 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAM17852.1 - 4.3e-20 72.2 5.9 8.6e-14 51.7 0.0 4.0 4 0 0 4 4 4 2 Microtubule binding EGF_2 PF07974.13 GAM17855.1 - 0.0015 18.9 11.1 0.003 17.9 11.1 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 GAM17855.1 - 0.34 11.0 2.3 0.95 9.6 2.3 1.8 1 0 0 1 1 1 0 Tenascin EGF domain RL10P_insert PF17777.1 GAM17856.1 - 4.5e-16 58.6 0.0 6.7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 GAM17856.1 - 9.4e-15 54.6 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RhoGEF PF00621.20 GAM17857.1 - 5.5e-43 147.3 0.1 5.5e-43 147.3 0.1 2.0 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 GAM17857.1 - 5.2e-06 26.9 0.0 1.2e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 GAM17857.1 - 9.2e-05 22.3 0.4 0.00041 20.2 0.4 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 GAM17857.1 - 0.00063 19.6 0.1 0.029 14.2 0.0 2.3 2 0 0 2 2 2 1 PH domain IQ PF00612.27 GAM17857.1 - 0.042 13.7 1.1 0.086 12.7 1.1 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif Gal4_dimer PF03902.13 GAM17857.1 - 0.26 11.5 2.7 0.77 10.0 2.7 1.8 1 0 0 1 1 1 0 Gal4-like dimerisation domain G_path_suppress PF15991.5 GAM17857.1 - 6.9 6.7 14.1 0.11 12.6 4.9 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor SOG2 PF10428.9 GAM17857.1 - 8.5 5.4 31.1 1.4 8.0 2.8 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Glycolipid_bind PF06475.11 GAM17858.1 - 0.08 12.4 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Putative glycolipid-binding Trypan_PARP PF05887.11 GAM17858.1 - 0.35 10.9 34.6 0.43 10.6 28.9 2.2 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Merozoite_SPAM PF07133.11 GAM17858.1 - 1.6 8.7 8.5 0.058 13.4 2.7 1.5 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) YjeF_N PF03853.15 GAM17859.1 - 2e-38 132.0 0.0 2.3e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Trypsin_2 PF13365.6 GAM17860.1 - 4e-32 112.2 0.1 3.4e-18 67.0 0.0 2.9 2 1 0 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.26 GAM17860.1 - 1.2e-09 38.4 0.2 1.4e-06 28.3 0.1 2.6 2 1 0 2 2 2 2 Trypsin Peptidase_S46 PF10459.9 GAM17860.1 - 0.0028 16.4 0.6 5.3 5.6 0.5 3.2 3 0 0 3 3 3 2 Peptidase S46 FAT PF02259.23 GAM17861.1 - 2.9e-40 138.6 0.0 7.5e-40 137.2 0.0 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 GAM17861.1 - 0.0004 20.3 0.2 0.52 10.1 0.0 2.4 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase MKT1_N PF12247.8 GAM17861.1 - 0.28 11.6 3.2 4.2 7.8 0.1 4.1 4 0 0 4 4 4 0 Temperature dependent protein affecting M2 dsRNA replication Spt20 PF12090.8 GAM17862.1 - 0.0066 16.1 4.5 0.0066 16.1 4.5 3.0 3 0 0 3 3 3 1 Spt20 family SUIM_assoc PF16619.5 GAM17862.1 - 0.048 13.7 10.1 0.17 12.0 7.2 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RP-C_C PF11800.8 GAM17862.1 - 0.12 12.4 3.3 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region Rpp20 PF12328.8 GAM17862.1 - 0.59 10.1 2.3 1.3 8.9 2.3 1.5 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P HD_assoc PF13286.6 GAM17862.1 - 3 8.4 4.5 3.6 8.2 0.3 3.0 4 0 0 4 4 4 0 Phosphohydrolase-associated domain 5_nucleotid PF05761.14 GAM17863.1 - 2e-166 554.5 1.4 2.9e-166 553.9 1.4 1.2 1 0 0 1 1 1 1 5' nucleotidase family Metallophos PF00149.28 GAM17864.1 - 7.6e-18 65.8 0.5 1.2e-17 65.1 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GAM17864.1 - 1.2e-17 64.2 3.6 1.2e-17 64.2 3.6 1.8 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 GAM17864.1 - 6.6e-16 58.9 0.1 3.8e-15 56.5 0.0 2.4 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 GAM17864.1 - 4.7e-05 23.7 0.0 0.00011 22.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain VPS13_C PF16909.5 GAM17865.1 - 0.49 10.2 5.1 0.48 10.2 2.2 2.2 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal SdrD_B PF17210.3 GAM17867.1 - 2.5e-83 275.7 51.6 1.5e-12 47.7 0.1 12.6 12 0 0 12 12 12 11 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM17867.1 - 1.3e-12 47.8 20.0 0.025 14.8 0.1 10.8 10 2 0 10 10 10 3 Carboxypeptidase regulatory-like domain SpaA PF17802.1 GAM17867.1 - 1.8e-10 41.0 31.4 2 8.8 0.0 10.8 8 3 1 9 9 9 3 Prealbumin-like fold domain DUF3707 PF12499.8 GAM17867.1 - 1.2e-07 32.4 5.1 12 6.5 0.1 8.9 7 2 0 9 9 9 1 Pherophorin Y_Y_Y PF07495.13 GAM17867.1 - 0.00064 19.6 0.5 51 3.9 0.0 7.0 9 0 0 9 9 9 0 Y_Y_Y domain W_rich_C PF07483.11 GAM17867.1 - 0.0053 16.9 3.8 5.5 7.2 0.1 4.3 4 0 0 4 4 4 1 Tryptophan-rich Synechocystis species C-terminal domain fn3_3 PF14686.6 GAM17867.1 - 0.014 15.2 0.1 5.6 6.8 0.0 4.7 6 0 0 6 6 6 0 Polysaccharide lyase family 4, domain II eIF-5_eIF-2B PF01873.17 GAM17867.1 - 0.026 14.4 0.1 9.1 6.2 0.0 3.8 4 0 0 4 4 4 0 Domain found in IF2B/IF5 DUF2012 PF09430.10 GAM17867.1 - 0.041 14.0 0.0 1.2 9.3 0.0 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF2012) FlgD_ig PF13860.6 GAM17867.1 - 0.054 13.4 10.8 17 5.3 0.0 8.2 11 0 0 11 11 11 0 FlgD Ig-like domain Invasin_D3 PF09134.10 GAM17867.1 - 0.22 11.8 21.1 2 8.8 0.1 7.3 7 0 0 7 7 7 0 Invasin, domain 3 CarbopepD_reg_2 PF13715.6 GAM17867.1 - 0.24 11.4 11.9 1.5 8.8 0.3 5.4 5 0 0 5 5 5 0 CarboxypepD_reg-like domain VCBS PF13517.6 GAM17867.1 - 1 10.0 16.1 2.4 8.8 0.0 6.0 6 0 0 6 6 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4211 PF13926.6 GAM17869.1 - 4.9e-27 94.8 0.5 3e-26 92.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Ank_2 PF12796.7 GAM17870.1 - 2.1e-45 153.2 3.8 4.2e-12 46.5 0.1 5.5 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM17870.1 - 2.8e-39 133.0 2.2 2e-07 31.4 0.0 8.7 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM17870.1 - 3.1e-30 103.8 2.7 2.1e-08 34.3 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM17870.1 - 3.1e-30 100.8 9.9 2.9e-06 27.2 0.0 11.9 13 0 0 13 13 13 7 Ankyrin repeat Ank PF00023.30 GAM17870.1 - 3.8e-26 90.3 7.1 0.0004 20.7 0.0 10.8 11 0 0 11 11 11 6 Ankyrin repeat Plant_tran PF04827.14 GAM17870.1 - 0.026 14.1 0.0 7.6 6.1 0.0 2.6 3 0 0 3 3 3 0 Plant transposon protein VIT1 PF01988.19 GAM17871.1 - 1.6e-25 90.3 0.5 6.4e-25 88.3 0.0 1.9 1 1 1 2 2 2 1 VIT family Na_Ala_symp PF01235.17 GAM17871.1 - 0.0041 16.5 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 Sodium:alanine symporter family AIF_C PF14721.6 GAM17871.1 - 0.057 13.8 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Cyt-b5 PF00173.28 GAM17872.1 - 6.1e-17 61.5 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-CDGSH PF09360.10 GAM17872.1 - 2.4e-06 27.6 0.6 7.3e-06 26.1 0.6 1.9 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type TFIIA PF03153.13 GAM17872.1 - 0.61 10.0 22.9 0.76 9.7 22.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 GAM17872.1 - 3.1 7.9 18.8 0.14 12.2 8.6 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Mucin PF01456.17 GAM17872.1 - 4.2 7.4 21.3 2.3 8.2 7.4 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Ashwin PF15323.6 GAM17872.1 - 4.5 7.2 38.8 0.055 13.5 13.4 2.2 2 0 0 2 2 2 0 Developmental protein Metallophos PF00149.28 GAM17873.1 - 4.2e-05 24.1 0.9 7.2e-05 23.4 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_16 PF00722.21 GAM17874.1 - 7e-24 84.2 1.4 8.6e-24 84.0 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 GAM17874.1 - 3.1e-07 29.2 3.4 7.8e-06 24.6 0.9 2.4 1 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Beta-lactamase PF00144.24 GAM17877.1 - 9.6e-42 143.4 0.0 1.4e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_M15 PF01427.17 GAM17877.1 - 2.2e-27 96.2 0.0 4.7e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 D-ala-D-ala dipeptidase Peptidase_S11 PF00768.20 GAM17877.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Tropomyosin_1 PF12718.7 GAM17878.1 - 8.5e-06 26.0 7.0 8.5e-06 26.0 7.0 3.2 2 1 0 3 3 3 1 Tropomyosin like zf-C4H2 PF10146.9 GAM17878.1 - 0.0047 17.3 11.7 0.0047 17.3 11.7 2.6 1 1 1 2 2 1 1 Zinc finger-containing protein Nmad5 PF18757.1 GAM17878.1 - 0.011 16.0 10.8 0.26 11.5 1.3 2.7 1 1 2 3 3 3 0 Nucleotide modification associated domain 5 DUF641 PF04859.12 GAM17878.1 - 0.011 16.1 7.9 0.011 16.1 7.9 2.9 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) SPT16 PF08644.11 GAM17878.1 - 0.014 15.6 5.6 0.014 15.6 5.6 2.2 3 0 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) TolA_bind_tri PF16331.5 GAM17878.1 - 0.039 14.0 2.6 0.039 14.0 2.6 2.6 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF2076 PF09849.9 GAM17878.1 - 0.04 14.0 0.2 0.04 14.0 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) BRE1 PF08647.11 GAM17878.1 - 0.043 13.9 24.8 0.06 13.4 0.9 3.4 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase PKcGMP_CC PF16808.5 GAM17878.1 - 0.049 13.5 4.9 0.089 12.7 2.2 2.8 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase APG6_N PF17675.1 GAM17878.1 - 0.051 14.1 27.1 1.6 9.3 10.8 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 GAM17878.1 - 0.097 13.1 22.2 1.1 9.6 9.5 2.1 1 1 1 2 2 2 0 Fez1 HrpB7 PF09486.10 GAM17878.1 - 0.14 12.6 4.8 0.42 11.0 0.3 2.7 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) TMF_TATA_bd PF12325.8 GAM17878.1 - 0.16 12.2 20.5 0.76 10.0 4.8 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Med4 PF10018.9 GAM17878.1 - 0.21 11.2 14.5 0.39 10.4 3.4 2.4 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Prefoldin_2 PF01920.20 GAM17878.1 - 0.26 11.3 23.7 0.74 9.8 5.9 4.0 3 1 0 3 3 3 0 Prefoldin subunit CREPT PF16566.5 GAM17878.1 - 0.27 11.4 15.0 1.2 9.3 0.6 3.1 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour YtxH PF12732.7 GAM17878.1 - 0.36 11.4 5.9 3.8 8.1 0.9 3.1 2 1 1 3 3 3 0 YtxH-like protein DUF948 PF06103.11 GAM17878.1 - 0.66 10.3 10.9 0.7 10.2 3.7 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 GAM17878.1 - 0.69 10.0 30.4 2.8 8.0 21.7 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Tweety PF04906.13 GAM17878.1 - 0.75 8.4 6.7 1.5 7.4 0.3 2.3 2 1 0 2 2 2 0 Tweety Spc24 PF08286.11 GAM17878.1 - 1.1 9.5 26.0 2.2 8.5 5.7 3.3 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 CC2-LZ PF16516.5 GAM17878.1 - 1.1 9.6 17.4 3 8.2 0.3 3.2 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Seryl_tRNA_N PF02403.22 GAM17878.1 - 1.2 9.4 18.8 11 6.3 0.3 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain LPP PF04728.13 GAM17878.1 - 1.6 9.2 8.9 2.9 8.4 0.3 3.4 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Atg14 PF10186.9 GAM17878.1 - 2.8 7.0 28.3 0.24 10.4 18.9 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_MT_bd PF06657.13 GAM17878.1 - 2.9 8.4 21.5 7.1 7.2 0.3 4.2 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF4164 PF13747.6 GAM17878.1 - 3 8.2 13.1 0.96 9.8 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.12 GAM17878.1 - 4.2 7.9 12.8 11 6.6 3.5 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Uds1 PF15456.6 GAM17878.1 - 4.9 7.3 18.8 9.1 6.5 0.8 3.4 1 1 1 2 2 2 0 Up-regulated During Septation CENP-F_leu_zip PF10473.9 GAM17878.1 - 5.3 7.1 25.5 1.2 9.2 11.4 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFT57 PF10498.9 GAM17878.1 - 5.4 5.9 29.2 0.96 8.3 21.6 2.3 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 SlyX PF04102.12 GAM17878.1 - 5.6 7.7 10.4 0.56 10.9 2.3 3.1 3 1 0 3 3 2 0 SlyX Laminin_II PF06009.12 GAM17878.1 - 5.7 7.0 14.5 0.77 9.8 5.5 3.0 3 0 0 3 3 3 0 Laminin Domain II Fib_alpha PF08702.10 GAM17878.1 - 8.6 6.5 27.5 0.33 11.1 12.7 3.0 1 1 2 3 3 2 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 GAM17878.1 - 8.9 6.4 14.4 8.5 6.5 0.4 2.9 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RhoGAP PF00620.27 GAM17879.1 - 2.3e-38 131.4 1.7 3e-38 131.0 0.2 1.9 2 0 0 2 2 2 1 RhoGAP domain C2 PF00168.30 GAM17879.1 - 3.6e-20 72.2 0.0 1.4e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 C2 domain PH PF00169.29 GAM17879.1 - 3.7e-12 46.7 1.5 9e-12 45.4 0.6 2.2 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 GAM17879.1 - 1.2e-08 35.0 2.9 1.3e-08 34.9 0.2 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 GAM17879.1 - 6.5e-05 23.3 0.0 0.00042 20.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 GAM17879.1 - 0.0082 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain IZUMO PF15005.6 GAM17879.1 - 0.21 12.1 3.3 0.54 10.8 3.1 1.9 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated WD40 PF00400.32 GAM17880.1 - 1.4e-06 28.9 0.2 0.0074 17.1 0.3 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17880.1 - 6.2e-06 26.4 0.1 0.43 10.9 0.0 3.6 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 GAM17880.1 - 0.011 15.6 0.4 2.8 7.9 0.1 3.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Ge1_WD40 PF16529.5 GAM17880.1 - 0.012 14.6 2.5 1.6 7.6 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 GAM17881.1 - 4.1e-07 30.1 0.0 0.0012 18.9 0.0 2.6 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 GAM17881.1 - 0.0071 16.3 2.5 0.016 15.1 2.5 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex RhoGEF PF00621.20 GAM17882.1 - 7.2e-39 133.9 0.7 7.2e-39 133.9 0.7 3.5 3 1 0 3 3 3 1 RhoGEF domain IQ PF00612.27 GAM17882.1 - 4.9e-06 25.9 0.2 1.1e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif IQ_SEC7_PH PF16453.5 GAM17882.1 - 3.7e-05 23.7 0.2 0.00018 21.5 0.2 2.2 1 0 0 1 1 1 1 PH domain PH PF00169.29 GAM17882.1 - 0.0026 18.2 0.7 0.011 16.3 0.0 2.4 2 0 0 2 2 2 1 PH domain Beach PF02138.18 GAM17883.1 - 7.3e-121 402.8 0.6 7.3e-121 402.8 0.6 2.0 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.32 GAM17883.1 - 3.3e-10 40.4 15.5 9.8e-05 23.1 0.4 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat PH_BEACH PF14844.6 GAM17883.1 - 8.2e-10 38.7 0.0 8.2e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 GAM17883.1 - 1.2e-08 35.3 0.0 3.5e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 GAM17883.1 - 5.8e-08 32.3 3.1 3.4e-07 29.8 0.5 3.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) DUF4800 PF16057.5 GAM17883.1 - 0.0028 17.0 8.6 0.0083 15.4 8.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) Peptidase_M20 PF01546.28 GAM17884.1 - 5.6e-33 114.4 0.0 7e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM17884.1 - 3.8e-21 75.0 0.0 7.3e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM17884.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 G8 PF10162.9 GAM17885.1 - 2.6e-19 69.5 0.1 9.1e-19 67.7 0.1 2.0 1 0 0 1 1 1 1 G8 domain DUF4097 PF13349.6 GAM17885.1 - 0.12 11.8 2.3 0.16 11.3 1.1 1.8 2 0 0 2 2 2 0 Putative adhesin KTI12 PF08433.10 GAM17886.1 - 2.2e-12 47.0 4.1 2.2e-12 47.0 4.1 1.7 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAM17886.1 - 0.095 12.9 0.0 0.85 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF29 PF01724.16 GAM17886.1 - 0.14 12.4 4.5 0.12 12.6 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF29 RNase_J_C PF17770.1 GAM17886.1 - 0.15 13.2 1.7 44 5.2 0.0 3.5 2 1 1 3 3 3 0 Ribonuclease J C-terminal domain Thiolase_N PF00108.23 GAM17887.1 - 1.2e-65 221.5 0.0 2e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM17887.1 - 1.6e-45 153.7 0.2 3.9e-45 152.5 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAM17887.1 - 8.8e-05 22.2 1.0 0.00028 20.6 0.3 2.0 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 GAM17887.1 - 0.015 15.4 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 GAM17887.1 - 0.034 14.0 1.2 0.76 9.7 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2802 PF10975.8 GAM17887.1 - 0.068 13.3 0.0 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Lipase_3 PF01764.25 GAM17887.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FNIP PF05725.12 GAM17889.1 - 9.7e-28 96.1 25.8 2.2e-06 27.7 0.0 8.6 4 3 4 8 8 8 8 FNIP Repeat LRR_4 PF12799.7 GAM17889.1 - 0.01 16.2 22.7 0.13 12.7 0.2 6.7 5 3 2 8 8 8 0 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 GAM17889.1 - 0.016 15.2 6.9 1.3 9.0 2.6 4.2 3 2 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) NLE PF08154.12 GAM17889.1 - 0.058 13.9 4.7 1.2 9.7 0.1 3.8 4 0 0 4 4 4 0 NLE (NUC135) domain DUF2576 PF10845.8 GAM17890.1 - 0.14 11.7 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) FmiP_Thoc5 PF09766.9 GAM17891.1 - 1e-61 209.3 14.7 1e-61 209.3 14.7 1.9 2 1 0 2 2 2 1 Fms-interacting protein/Thoc5 EMP24_GP25L PF01105.24 GAM17892.1 - 6e-50 169.7 0.3 7.1e-50 169.5 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_A3 PF02160.15 GAM17892.1 - 0.039 13.4 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) CHU_C PF13585.6 GAM17892.1 - 0.097 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of CHU protein family Leo1 PF04004.13 GAM17892.1 - 0.33 10.8 2.6 0.91 9.3 2.2 1.9 1 1 0 1 1 1 0 Leo1-like protein ATP_bind_3 PF01171.20 GAM17893.1 - 3.4e-40 137.7 0.0 5.8e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 PP-loop family QueC PF06508.13 GAM17893.1 - 0.0026 17.3 0.0 0.28 10.7 0.0 2.8 1 1 1 2 2 2 2 Queuosine biosynthesis protein QueC DUF3165 PF11364.8 GAM17894.1 - 0.13 12.6 1.7 0.14 12.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) DUF4064 PF13273.6 GAM17894.1 - 0.29 11.4 7.1 1.3 9.3 0.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Ribosomal_S21e PF01249.18 GAM17895.1 - 1.9e-38 130.4 0.1 2.1e-38 130.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Patatin PF01734.22 GAM17896.1 - 3.3e-18 66.6 0.3 2.4e-17 63.8 0.0 2.3 2 1 0 2 2 2 1 Patatin-like phospholipase Sporozoite_P67 PF05642.11 GAM17896.1 - 0.0058 14.8 0.2 0.0058 14.8 0.2 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen FPN1 PF06963.12 GAM17897.1 - 1.3e-81 274.4 16.8 1.6e-81 274.1 16.8 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1_like PF12832.7 GAM17897.1 - 7.1e-05 21.8 11.6 0.00099 18.1 2.3 2.2 1 1 1 2 2 2 2 MFS_1 like family Cwf_Cwc_15 PF04889.12 GAM17897.1 - 0.94 9.2 7.5 1.7 8.3 7.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GATase_4 PF13230.6 GAM17898.1 - 1e-14 54.1 0.0 1e-13 50.8 0.0 2.0 1 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 GAM17898.1 - 4.3e-11 43.2 0.0 7.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Dicty_CTDC PF00526.18 GAM17899.1 - 0.00023 21.0 45.4 0.002 18.0 15.5 22.3 19 7 0 19 19 19 8 Dictyostelium (slime mold) repeat OTU PF02338.19 GAM17900.1 - 1.3e-06 28.9 0.0 2.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease TBK1_ULD PF18396.1 GAM17900.1 - 0.0037 17.2 0.1 0.019 14.9 0.0 2.1 3 0 0 3 3 3 1 TANK binding kinase 1 ubiquitin-like domain UN_NPL4 PF11543.8 GAM17900.1 - 0.0051 17.3 1.0 0.016 15.7 0.0 2.2 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 GAM17900.1 - 0.016 15.0 0.3 0.11 12.3 0.3 2.3 1 1 0 1 1 1 0 Ubiquitin family GATA PF00320.27 GAM17901.1 - 6.2e-14 51.3 3.7 2.2e-13 49.5 3.7 2.0 1 0 0 1 1 1 1 GATA zinc finger Rod_cone_degen PF15201.6 GAM17902.1 - 0.13 12.4 0.8 0.32 11.1 0.8 1.6 1 0 0 1 1 1 0 Progressive rod-cone degeneration Trypan_PARP PF05887.11 GAM17903.1 - 0.89 9.5 3.6 1.7 8.6 3.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ras PF00071.22 GAM17904.1 - 1.4e-50 171.1 0.3 1.6e-50 170.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM17904.1 - 4.5e-18 65.6 0.0 8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM17904.1 - 3.2e-09 36.5 0.1 4.2e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM17904.1 - 7.8e-06 25.6 0.2 1.4e-05 24.8 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM17904.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM17904.1 - 0.021 14.7 0.1 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF3568 PF12092.8 GAM17904.1 - 0.09 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) MMR_HSR1_Xtn PF16897.5 GAM17904.1 - 0.1 12.6 0.3 0.18 11.8 0.1 1.5 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Cyclin PF08613.11 GAM17905.1 - 3.9e-31 108.6 0.0 5.2e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAM17905.1 - 9.7e-10 38.3 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain WH2 PF02205.20 GAM17906.1 - 0.13 12.2 0.0 42 4.1 0.0 3.0 3 0 0 3 3 3 0 WH2 motif SPX PF03105.19 GAM17908.1 - 6.5e-05 23.0 0.0 0.00024 21.2 0.0 1.7 1 1 1 2 2 2 1 SPX domain DUF1068 PF06364.12 GAM17908.1 - 0.078 12.8 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Sedlin_N PF04628.13 GAM17909.1 - 2.4e-48 163.6 1.7 2.7e-48 163.4 1.7 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAM17909.1 - 1.7e-09 37.8 1.1 8.4e-09 35.5 1.1 1.9 1 1 0 1 1 1 1 Sybindin-like family DUF508 PF04370.12 GAM17909.1 - 0.062 13.0 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) YecM PF06185.12 GAM17910.1 - 3.2e-39 134.4 0.6 4.6e-39 133.9 0.6 1.2 1 0 0 1 1 1 1 YecM protein FH2 PF02181.23 GAM17912.1 - 6.8e-95 318.3 3.9 9e-95 317.9 2.2 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 GAM17912.1 - 3.8e-29 101.6 0.7 3.8e-29 101.6 0.7 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAM17912.1 - 4.7e-21 75.3 3.3 4.7e-21 75.3 3.3 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain PRKCSH-like PF12999.7 GAM17913.1 - 1.6e-42 145.3 11.7 1.6e-42 145.3 11.7 2.6 1 1 3 4 4 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 GAM17913.1 - 1.5e-26 92.9 2.5 1.8e-26 92.7 0.0 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 GAM17913.1 - 0.0021 18.2 16.5 0.14 12.4 3.0 3.1 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A PRKCSH PF07915.13 GAM17913.1 - 0.0086 17.1 0.8 0.0086 17.1 0.8 3.1 3 2 0 3 3 2 1 Glucosidase II beta subunit-like protein TPR_MLP1_2 PF07926.12 GAM17913.1 - 0.82 9.7 30.8 0.024 14.7 17.5 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 GAM17913.1 - 0.93 8.8 19.0 1.6 8.0 19.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fmp27_WPPW PF10359.9 GAM17913.1 - 1.5 7.6 14.6 2.2 7.1 14.6 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain SAPS PF04499.15 GAM17913.1 - 2 7.1 15.0 2.7 6.7 15.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SlyX PF04102.12 GAM17913.1 - 3.9 8.2 14.7 0.15 12.7 3.8 2.7 1 1 1 2 2 2 0 SlyX Macoilin PF09726.9 GAM17913.1 - 4.6 5.7 17.1 5.8 5.3 17.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF3584 PF12128.8 GAM17913.1 - 7.8 3.9 26.7 9.7 3.6 26.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DDHD PF02862.17 GAM17913.1 - 8.8 6.4 6.9 14 5.7 6.9 1.3 1 0 0 1 1 1 0 DDHD domain EIIBC-GUT_N PF03612.14 GAM17913.1 - 9.9 5.9 9.1 2.1e+02 1.5 9.8 2.6 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus FNIP PF05725.12 GAM17914.1 - 8.6e-32 109.1 12.8 2.6e-10 40.3 0.1 4.9 5 0 0 5 5 5 4 FNIP Repeat FNIP PF05725.12 GAM17915.1 - 5.7e-32 109.6 38.2 1.6e-11 44.2 2.4 6.6 2 2 5 8 8 8 8 FNIP Repeat hnRNP_Q_AcD PF18360.1 GAM17915.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain FNIP PF05725.12 GAM17916.1 - 5.1e-47 157.8 23.6 5.7e-15 55.2 0.9 4.7 2 2 0 4 4 4 4 FNIP Repeat TatD_DNase PF01026.21 GAM17918.1 - 2.3e-32 112.4 0.1 3.2e-32 111.9 0.1 1.2 1 0 0 1 1 1 1 TatD related DNase NUDIX PF00293.28 GAM17918.1 - 1.8e-18 66.8 0.3 3.9e-18 65.8 0.3 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4211 PF13926.6 GAM17918.1 - 0.00077 19.5 0.1 0.035 14.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) T2SS_PulS_OutS PF09691.10 GAM17918.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system pilotin lipoprotein (PulS_OutS) FNIP PF05725.12 GAM17919.1 - 7.3e-29 99.7 25.6 3.2e-08 33.6 0.6 7.2 5 2 3 8 8 8 7 FNIP Repeat LRR_8 PF13855.6 GAM17919.1 - 0.42 10.4 4.9 55 3.6 0.4 4.3 4 0 0 4 4 4 0 Leucine rich repeat PS_Dcarbxylase PF02666.15 GAM17920.1 - 2.5e-57 193.7 0.1 4.4e-57 192.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 GAM17920.1 - 7.7e-23 80.7 0.0 1.9e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_5 PF13202.6 GAM17920.1 - 7e-07 28.5 0.3 1.8e-06 27.2 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 GAM17920.1 - 4.7e-06 25.8 0.3 1.5e-05 24.2 0.2 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 GAM17920.1 - 6.7e-06 26.5 0.1 4.3e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM17920.1 - 0.00065 19.4 0.0 0.0059 16.4 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 GAM17920.1 - 0.0069 16.2 0.1 0.023 14.5 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair DUF4690 PF15756.5 GAM17921.1 - 0.00086 19.9 0.1 0.0019 18.7 0.1 1.6 1 0 0 1 1 1 1 Small Novel Rich in Cartilage EphA2_TM PF14575.6 GAM17921.1 - 0.032 15.1 0.1 0.055 14.4 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Beta-APP PF03494.13 GAM17921.1 - 0.76 9.7 4.8 0.95 9.4 2.5 2.1 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) Syndecan PF01034.20 GAM17921.1 - 3.1 7.8 7.1 11 6.0 7.1 2.0 1 1 0 1 1 1 0 Syndecan domain DSPc PF00782.20 GAM17922.1 - 2.5e-30 105.0 4.0 9e-30 103.2 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 GAM17922.1 - 1.1e-13 50.6 22.9 6.8e-08 32.2 0.2 5.7 4 1 3 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 GAM17922.1 - 3.1e-11 43.3 22.9 0.00096 19.5 0.3 6.0 4 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAM17922.1 - 0.00025 20.6 5.1 0.019 14.5 0.5 2.6 1 1 1 2 2 2 2 Leucine-rich repeat Y_phosphatase PF00102.27 GAM17922.1 - 0.0033 17.0 0.0 0.0033 17.0 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase LRR_1 PF00560.33 GAM17922.1 - 0.24 12.1 21.8 7.3 7.6 0.4 7.9 7 1 0 7 7 7 0 Leucine Rich Repeat Pkinase PF00069.25 GAM17923.1 - 1.5e-26 93.3 0.0 3.5e-26 92.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17923.1 - 6e-21 74.9 0.0 2.1e-20 73.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 GAM17923.1 - 0.0079 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 GAM17924.1 - 2e-63 214.3 2.6 2.1e-63 214.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17924.1 - 2.2e-45 155.0 0.0 2.2e-45 155.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GAM17924.1 - 0.0075 16.2 0.0 0.028 14.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAM17924.1 - 0.022 13.8 0.3 0.045 12.8 0.3 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 GAM17924.1 - 0.024 13.4 18.2 26 3.4 18.1 3.1 2 1 0 2 2 2 0 Fungal protein kinase NAP PF00956.18 GAM17924.1 - 0.063 12.4 4.7 0.099 11.8 4.7 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) G_path_suppress PF15991.5 GAM17924.1 - 0.58 10.3 25.1 6.2 6.9 19.4 2.3 2 0 0 2 2 2 0 G-protein pathway suppressor SARAF PF06682.12 GAM17924.1 - 7.9 6.0 19.1 14 5.2 19.1 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PIP5K PF01504.18 GAM17926.1 - 1.3e-33 116.4 1.1 3.1e-31 108.6 0.3 3.9 3 2 1 4 4 4 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 GAM17926.1 - 5.7e-20 71.4 0.1 3.1e-19 69.0 0.1 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 GAM17926.1 - 6.8e-18 64.6 7.6 2.3e-17 62.9 7.6 2.0 1 0 0 1 1 1 1 FYVE zinc finger HlyD_3 PF13437.6 GAM17926.1 - 0.032 14.9 0.2 0.55 11.0 0.0 2.6 2 0 0 2 2 2 0 HlyD family secretion protein Ig_mannosidase PF17753.1 GAM17928.1 - 2.8e-13 49.4 0.1 8e-13 48.0 0.0 1.8 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 GAM17928.1 - 1.8e-07 31.7 0.0 4.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 GAM17928.1 - 1.2e-06 29.2 1.7 2.1e-06 28.3 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 GAM17928.1 - 1.9e-05 24.6 0.1 5.4e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Pkinase PF00069.25 GAM17929.1 - 6.8e-47 160.0 0.2 3.3e-26 92.2 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17929.1 - 6.5e-18 64.9 0.1 1.3e-13 50.9 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase DUF1499 PF07386.11 GAM17929.1 - 0.0012 19.4 3.0 0.0012 19.4 3.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1499) Kinase-like PF14531.6 GAM17929.1 - 0.023 14.0 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Kinase-like BAF1_ABF1 PF04684.13 GAM17929.1 - 0.067 12.2 9.0 0.28 10.2 2.7 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Dicty_REP PF05086.12 GAM17929.1 - 0.24 9.3 11.2 0.0052 14.9 1.7 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein SAGA-Tad1 PF12767.7 GAM17929.1 - 0.29 10.8 8.3 2 8.1 2.7 2.9 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Ndc1_Nup PF09531.10 GAM17929.1 - 0.64 8.6 11.2 1.4 7.5 1.6 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Pkinase_fungal PF17667.1 GAM17929.1 - 1.1 7.9 7.8 5.3 5.7 7.8 2.3 1 1 0 1 1 1 0 Fungal protein kinase MRVI1 PF05781.12 GAM17929.1 - 1.4 7.5 9.8 0.21 10.3 1.5 2.1 2 0 0 2 2 2 0 MRVI1 protein FAM220 PF15487.6 GAM17929.1 - 2.8 7.5 13.8 3.6 7.1 5.1 2.4 2 0 0 2 2 2 0 FAM220 family RskA PF10099.9 GAM17929.1 - 5.1 7.4 12.4 2.2 8.5 1.2 2.8 3 0 0 3 3 2 0 Anti-sigma-K factor rskA PP2C_2 PF13672.6 GAM17930.1 - 5.3e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C DUF2112 PF09885.9 GAM17930.1 - 0.024 14.7 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) SpoIIE PF07228.12 GAM17930.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Myb_DNA-bind_4 PF13837.6 GAM17930.1 - 0.2 12.0 2.8 0.13 12.6 0.5 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Clat_adaptor_s PF01217.20 GAM17931.1 - 3.9e-48 163.0 5.6 4.6e-48 162.8 5.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 GAM17931.1 - 0.0035 17.4 0.1 0.0044 17.0 0.1 1.2 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 Coilin_N PF15862.5 GAM17932.1 - 0.0078 16.0 3.3 0.012 15.5 3.3 1.3 1 0 0 1 1 1 1 Coilin N-terminus EPL1 PF10513.9 GAM17932.1 - 0.042 14.2 4.8 0.053 13.9 4.8 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like TFIIA PF03153.13 GAM17932.1 - 0.2 11.6 24.7 0.24 11.4 24.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 GAM17932.1 - 0.24 11.3 8.8 0.3 11.1 8.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 GAM17932.1 - 0.27 9.9 10.3 0.34 9.6 10.3 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 GAM17932.1 - 2.4 8.2 6.0 3.2 7.7 6.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 GAM17932.1 - 3.6 6.3 11.8 4.6 5.9 11.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 GAM17932.1 - 4.2 7.5 11.3 6 7.0 11.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 GAM17932.1 - 8.6 5.3 12.1 31 3.4 10.8 1.9 2 0 0 2 2 2 0 Solute carrier family 12 LMBR1 PF04791.16 GAM17934.1 - 6.9e-26 91.2 21.0 9e-22 77.6 6.4 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein SHP PF03579.13 GAM17934.1 - 0.0051 16.8 2.0 0.0051 16.8 2.0 4.3 4 1 0 4 4 4 1 Small hydrophobic protein GLTP PF08718.11 GAM17934.1 - 0.085 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Anophelin PF10731.9 GAM17934.1 - 0.1 12.5 0.1 0.4 10.6 0.1 2.1 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito BTB_2 PF02214.22 GAM17935.1 - 2.3e-15 56.7 0.0 5.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain WD40_like PF17005.5 GAM17935.1 - 4.1e-05 23.0 1.3 9.3e-05 21.9 0.8 1.8 2 0 0 2 2 2 1 WD40-like domain Aminotran_1_2 PF00155.21 GAM17936.1 - 2.2e-58 198.2 0.0 2.5e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAM17936.1 - 0.00014 21.0 0.1 0.0016 17.4 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAM17936.1 - 0.033 12.7 0.0 0.12 10.9 0.0 1.7 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF1751 PF08551.10 GAM17936.1 - 0.15 12.7 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) GDC-P PF02347.16 GAM17937.1 - 5.2e-187 621.9 2.2 8.3e-178 591.6 0.0 2.7 3 1 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 GAM17937.1 - 4.7e-06 25.8 0.1 2.1e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAM17937.1 - 0.0011 18.3 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase ABC_transp_aux PF09822.9 GAM17937.1 - 0.15 11.5 0.0 1.5 8.2 0.0 2.2 1 1 0 1 1 1 0 ABC-type uncharacterized transport system FNIP PF05725.12 GAM17938.1 - 6.7e-43 144.6 24.1 7.3e-12 45.3 1.8 8.6 6 1 2 9 9 9 7 FNIP Repeat Toprim_C_rpt PF13368.6 GAM17938.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat 5_nucleotid PF05761.14 GAM17939.1 - 2.3e-57 194.9 0.8 3.3e-57 194.4 0.3 1.3 1 1 0 1 1 1 1 5' nucleotidase family HAD PF12710.7 GAM17939.1 - 0.0023 18.4 0.0 0.11 12.9 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM17939.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase GcpE PF04551.14 GAM17939.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 GcpE protein DUF43 PF01861.16 GAM17939.1 - 0.17 11.1 0.5 0.51 9.5 0.2 1.9 1 1 1 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain FH2 PF02181.23 GAM17940.1 - 1.7e-66 224.9 2.5 1.8e-65 221.5 0.3 2.9 2 1 1 3 3 3 1 Formin Homology 2 Domain DUF3361 PF11841.8 GAM17940.1 - 4.1e-13 49.5 0.0 1.1e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Drf_GBD PF06371.13 GAM17940.1 - 5e-07 29.5 0.1 1.5e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAM17940.1 - 0.045 13.4 0.0 0.16 11.6 0.0 1.9 1 0 0 1 1 1 0 Diaphanous FH3 Domain EF-hand_1 PF00036.32 GAM17941.1 - 1e-19 68.5 3.9 1.4e-05 24.3 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 GAM17941.1 - 2.4e-19 67.6 3.3 5.2e-05 22.9 0.0 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 GAM17941.1 - 1.8e-17 61.9 5.8 1.9e-06 27.1 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 GAM17941.1 - 3.7e-15 56.1 4.6 5.5e-11 42.8 0.6 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAM17941.1 - 1.3e-09 37.8 3.6 0.058 13.2 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 GAM17941.1 - 4e-05 23.5 0.3 0.16 11.9 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAM17941.1 - 0.0002 21.7 0.2 4.7 7.6 0.0 3.4 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GAM17941.1 - 0.00073 19.7 0.0 5.6 7.2 0.0 3.4 3 0 0 3 3 3 2 Dockerin type I domain Cir_Bir_Yir PF06022.11 GAM17941.1 - 0.069 12.6 2.0 0.11 12.0 2.0 1.3 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Catalase PF00199.19 GAM17942.1 - 4.8e-197 654.6 0.1 5.7e-197 654.4 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GAM17942.1 - 6.4e-23 80.7 0.0 1.5e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Peptidase_M16_C PF05193.21 GAM17943.1 - 2.2e-17 63.7 0.0 7e-11 42.5 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAM17943.1 - 2.9e-10 40.3 0.0 7.5e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 GAM17943.1 - 5.9e-05 22.3 0.0 0.00011 21.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16C associated TFIIA PF03153.13 GAM17943.1 - 2.2 8.2 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3439 PF11921.8 GAM17943.1 - 7.5 6.5 8.6 0.46 10.5 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Nop14 PF04147.12 GAM17943.1 - 8.6 4.4 14.5 14 3.7 14.5 1.2 1 0 0 1 1 1 0 Nop14-like family Acetyltransf_1 PF00583.25 GAM17944.1 - 6.4e-17 61.9 0.1 7.9e-17 61.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM17944.1 - 5.8e-10 39.5 0.1 9.4e-10 38.8 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM17944.1 - 1e-08 35.2 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM17944.1 - 7.4e-05 22.6 0.0 0.00017 21.5 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 GAM17944.1 - 0.00037 20.6 0.0 0.0008 19.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM17944.1 - 0.00047 20.2 0.0 0.00077 19.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 GAM17944.1 - 0.0016 19.1 0.0 0.0025 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAM17944.1 - 0.0031 17.0 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase adh_short PF00106.25 GAM17945.1 - 2.5e-49 167.4 0.0 3.6e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM17945.1 - 6.7e-34 117.5 0.0 9.9e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAM17945.1 - 1.7e-08 34.2 0.0 2.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 GAM17945.1 - 5.3e-08 33.0 0.0 8.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 GAM17945.1 - 0.0013 17.9 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 GAM17945.1 - 0.0064 16.0 0.1 0.0099 15.4 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAM17945.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lipase_GDSL PF00657.22 GAM17946.1 - 2e-10 41.0 0.0 3.2e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAM17946.1 - 8.1e-05 23.1 0.0 0.00039 20.9 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family zf-RRN7 PF11781.8 GAM17946.1 - 0.067 12.9 0.4 0.34 10.7 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 FtsX PF02687.21 GAM17947.1 - 7.1e-14 52.1 22.9 2.8e-08 34.1 8.5 6.6 6 1 1 7 7 7 2 FtsX-like permease family Spt20 PF12090.8 GAM17947.1 - 0.066 12.8 5.9 0.12 11.9 5.9 1.3 1 0 0 1 1 1 0 Spt20 family tRNA-synt_1d PF00750.19 GAM17948.1 - 9.7e-76 255.0 0.0 2.2e-73 247.2 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAM17948.1 - 7e-22 77.8 0.0 7.4e-21 74.5 0.0 2.5 2 1 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 GAM17948.1 - 0.0012 19.4 0.0 0.032 14.8 0.0 3.1 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1 PF00133.22 GAM17948.1 - 0.034 12.4 0.0 0.19 9.9 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) TRAM PF01938.20 GAM17948.1 - 0.045 13.7 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 TRAM domain PH PF00169.29 GAM17949.1 - 4.6e-23 81.7 0.3 1.5e-22 80.1 0.0 2.1 2 0 0 2 2 2 1 PH domain PTEN_C2 PF10409.9 GAM17949.1 - 3.3e-20 72.2 0.1 1.7e-19 69.9 0.0 2.1 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein PH_11 PF15413.6 GAM17949.1 - 2e-08 34.6 3.7 3e-07 30.8 0.2 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 GAM17949.1 - 9e-07 29.1 0.0 3e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DSPc PF00782.20 GAM17949.1 - 5.7e-05 22.9 0.7 0.00021 21.1 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 GAM17949.1 - 7.3e-05 22.8 0.1 0.0003 20.8 0.0 2.0 3 0 0 3 3 3 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAM17949.1 - 9.1e-05 22.1 0.1 0.00037 20.1 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PH_3 PF14593.6 GAM17949.1 - 0.0014 18.7 0.4 0.005 16.9 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 GAM17949.1 - 0.0038 17.6 0.3 0.018 15.4 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain CDKN3 PF05706.12 GAM17949.1 - 0.0065 16.1 0.1 0.031 13.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 GAM17949.1 - 0.015 15.4 0.3 0.12 12.5 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 GAM17949.1 - 1.3 8.5 4.4 1.5 8.4 0.0 2.9 3 1 0 3 3 3 0 Tyrosine phosphatase family SRPRB PF09439.10 GAM17950.1 - 3.9e-34 117.6 0.0 5e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 GAM17950.1 - 3.4e-17 62.4 0.0 4.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM17950.1 - 7.6e-08 32.1 0.0 3.7e-05 23.4 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 GAM17950.1 - 9e-07 29.1 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAM17950.1 - 1.3e-05 24.5 1.1 0.019 14.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GAM17950.1 - 3.8e-05 23.3 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAM17950.1 - 4.6e-05 23.5 0.0 7.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAM17950.1 - 7.9e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GAM17950.1 - 0.00032 20.3 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 GAM17950.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NOG1 PF06858.14 GAM17950.1 - 0.1 12.4 0.2 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) PEPCK_ATP PF01293.20 GAM17950.1 - 0.37 9.4 1.1 0.51 8.9 1.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase DHHC PF01529.20 GAM17951.1 - 1.4e-36 125.6 5.2 1.9e-36 125.1 5.2 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase VMA21 PF09446.10 GAM17952.1 - 6.5e-15 55.0 7.5 1e-14 54.4 7.5 1.3 1 0 0 1 1 1 1 VMA21-like domain TFIIF_alpha PF05793.12 GAM17952.1 - 0.003 16.3 11.6 0.0034 16.1 11.6 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ORC6 PF05460.13 GAM17952.1 - 0.0062 15.9 6.7 0.0081 15.5 6.7 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Lin-8 PF03353.15 GAM17952.1 - 0.0063 16.1 9.2 0.0063 16.1 9.2 1.1 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist DUF2207 PF09972.9 GAM17952.1 - 0.014 14.2 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PMP22_Claudin PF00822.20 GAM17952.1 - 0.021 14.7 0.7 0.043 13.7 0.7 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family NST1 PF13945.6 GAM17952.1 - 0.051 13.7 14.2 0.078 13.1 14.2 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Tir_receptor_N PF07490.11 GAM17952.1 - 0.058 13.2 2.6 0.08 12.8 2.6 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Zip PF02535.22 GAM17952.1 - 0.092 11.9 0.9 0.11 11.7 0.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Miga PF10265.9 GAM17952.1 - 0.34 9.8 5.4 0.43 9.5 5.4 1.1 1 0 0 1 1 1 0 Mitoguardin FAM60A PF15396.6 GAM17952.1 - 0.46 10.4 6.0 0.56 10.2 6.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A GET2 PF08690.10 GAM17952.1 - 1.1 8.9 15.0 2.3 7.8 15.0 1.6 1 1 0 1 1 1 0 GET complex subunit GET2 DUF4692 PF15763.5 GAM17952.1 - 3.9 7.9 9.7 5.9 7.3 9.7 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) BIV_Env PF05858.12 GAM17952.1 - 5.4 5.1 5.4 9 4.3 5.4 1.3 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) RhoGAP PF00620.27 GAM17953.1 - 1.8e-06 27.8 0.1 2.9e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain zinc_ribbon_16 PF17034.5 GAM17954.1 - 2.2e-20 73.1 16.4 9.5e-20 71.1 16.6 2.1 1 1 1 2 2 2 1 Zinc-ribbon like family eIF2A PF08662.11 GAM17954.1 - 5.6e-05 23.1 0.1 0.84 9.5 0.0 3.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 GAM17954.1 - 0.00035 21.3 5.2 0.16 12.9 0.0 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat DUF5065 PF16723.5 GAM17954.1 - 0.75 9.8 3.7 1.4 8.9 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) GST_C PF00043.25 GAM17955.1 - 3.5e-13 49.6 0.0 5.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM17955.1 - 5.5e-12 45.9 0.0 1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM17955.1 - 1.4e-11 44.4 0.2 5.6e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM17955.1 - 2.2e-09 37.2 0.1 6.9e-09 35.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM17955.1 - 1.4e-08 35.1 0.0 4e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM17955.1 - 1.6e-08 34.7 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAM17955.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BSD PF03909.17 GAM17956.1 - 6e-08 32.6 0.2 1.4e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 BSD domain Spt20 PF12090.8 GAM17956.1 - 4.6 6.8 35.1 1.3 8.6 14.9 3.4 3 0 0 3 3 3 0 Spt20 family SAP30_Sin3_bdg PF13867.6 GAM17957.1 - 8.3e-19 67.7 0.1 1.3e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Suc_Fer-like PF06999.12 GAM17958.1 - 2.7e-36 125.3 0.0 3.7e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fer2_2 PF01799.20 GAM17958.1 - 0.016 15.2 0.0 5.3 7.1 0.0 2.6 2 0 0 2 2 2 0 [2Fe-2S] binding domain DEC-1_N PF04625.13 GAM17958.1 - 4.8 6.1 11.7 8 5.4 11.7 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Lactamase_B_2 PF12706.7 GAM17960.1 - 1.2e-38 132.7 0.3 1.8e-38 132.1 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM17960.1 - 6e-18 65.3 0.0 9.6e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HRM PF02793.22 GAM17960.1 - 0.024 14.9 3.9 0.046 14.0 3.9 1.4 1 0 0 1 1 1 0 Hormone receptor domain OTU PF02338.19 GAM17961.1 - 7.4e-14 52.3 0.1 1.7e-13 51.2 0.1 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Complex1_LYR_2 PF13233.6 GAM17961.1 - 0.31 11.8 4.3 15 6.5 0.0 2.6 3 0 0 3 3 3 0 Complex1_LYR-like MS_channel PF00924.18 GAM17962.1 - 3e-19 69.4 0.4 8.4e-19 67.9 0.4 1.8 1 0 0 1 1 1 1 Mechanosensitive ion channel EVI2A PF05399.11 GAM17962.1 - 0.0027 17.4 1.0 0.0027 17.4 1.0 1.8 2 0 0 2 2 2 1 Ectropic viral integration site 2A protein (EVI2A) ETRAMP PF09716.10 GAM17962.1 - 0.023 14.7 4.4 0.082 13.0 0.4 2.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF2157 PF09925.9 GAM17962.1 - 0.074 12.8 3.6 0.28 11.0 3.6 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) WD40 PF00400.32 GAM17964.1 - 1.7e-22 79.2 20.1 4e-05 24.3 0.3 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM17964.1 - 1.9e-10 40.9 6.1 0.00044 20.5 0.4 4.4 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAM17964.1 - 0.0013 17.6 0.4 1.1 7.9 0.1 2.6 3 0 0 3 3 3 2 Nup133 N terminal like Herpes_capsid PF06112.11 GAM17964.1 - 0.72 9.9 8.6 1.1 9.3 8.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF1713 PF08213.11 GAM17965.1 - 2e-09 37.2 21.4 3.1e-09 36.6 21.4 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) PRP3 PF08572.10 GAM17965.1 - 0.38 10.5 6.2 0.58 9.8 6.2 1.4 1 1 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Nuf2 PF03800.14 GAM17966.1 - 5.4e-35 120.5 0.5 5.4e-35 120.5 0.5 2.4 4 0 0 4 4 4 1 Nuf2 family DHR10 PF18595.1 GAM17966.1 - 1.3e-09 38.1 16.8 1.3e-09 38.1 16.8 3.9 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain ATG16 PF08614.11 GAM17966.1 - 0.023 14.9 36.2 0.12 12.6 7.0 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1713 PF08213.11 GAM17966.1 - 0.22 11.5 2.6 0.64 10.0 2.6 1.8 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) Laminin_II PF06009.12 GAM17966.1 - 0.42 10.6 30.5 3.1 7.8 4.1 3.5 1 1 2 3 3 3 0 Laminin Domain II Spc7 PF08317.11 GAM17966.1 - 0.49 9.2 46.9 0.16 10.9 8.8 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.8 GAM17966.1 - 0.86 9.7 42.7 0.23 11.5 5.1 4.3 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 GAM17966.1 - 1.5 8.8 34.5 3.1 7.8 5.7 4.6 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) SlyX PF04102.12 GAM17966.1 - 1.7 9.4 26.4 0.068 13.8 6.0 4.9 3 3 2 5 5 5 0 SlyX CALCOCO1 PF07888.11 GAM17966.1 - 1.9 7.3 46.4 1.2 8.0 18.7 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Phage_GP20 PF06810.11 GAM17966.1 - 2.1 8.1 37.1 0.34 10.7 7.9 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF3573 PF12097.8 GAM17966.1 - 2.2 7.0 11.6 0.18 10.6 5.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) MCPsignal PF00015.21 GAM17966.1 - 2.8 7.7 18.3 3.1 7.6 3.0 3.5 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF724 PF05266.14 GAM17966.1 - 8.8 6.1 43.3 3.3 7.5 18.2 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Ank_4 PF13637.6 GAM17967.1 - 8.7e-35 118.7 9.6 7.1e-07 29.7 0.1 8.3 3 2 6 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM17967.1 - 1.7e-33 114.3 9.3 0.00059 20.1 0.0 11.2 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM17967.1 - 2.6e-28 98.4 5.7 3.9e-08 33.8 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM17967.1 - 2e-18 64.5 2.4 0.43 11.3 0.0 10.6 10 1 1 11 11 11 4 Ankyrin repeat Ank PF00023.30 GAM17967.1 - 5e-05 23.6 3.9 4.3 8.0 0.1 7.0 4 2 2 6 6 6 1 Ankyrin repeat DUF4031 PF13223.6 GAM17967.1 - 0.079 13.2 1.2 8.4 6.7 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF4031) RIO1 PF01163.22 GAM17968.1 - 2e-48 164.5 0.2 2e-48 164.5 0.2 2.1 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 GAM17968.1 - 9.2e-31 105.9 0.1 3e-30 104.3 0.1 1.9 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 GAM17968.1 - 3.6e-09 36.9 0.2 3.4e-05 23.9 0.2 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GAM17968.1 - 1.3e-07 31.2 0.1 2e-06 27.3 0.1 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 GAM17968.1 - 0.0034 16.8 0.1 0.0094 15.3 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 GAM17968.1 - 0.029 13.7 0.0 0.086 12.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like LRR_6 PF13516.6 GAM17969.1 - 1.5e-06 27.8 4.5 0.97 9.7 0.1 5.8 6 0 0 6 6 6 2 Leucine Rich repeat F-box PF00646.33 GAM17969.1 - 0.00034 20.4 1.5 0.00067 19.5 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAM17969.1 - 0.004 17.0 1.1 0.008 16.1 0.3 2.0 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.13 GAM17969.1 - 0.0072 17.0 0.0 8.6 7.2 0.0 3.4 2 0 0 2 2 2 2 Leucine Rich Repeat FNIP PF05725.12 GAM17969.1 - 0.15 12.2 0.7 0.8 9.9 0.0 2.8 4 1 0 4 4 4 0 FNIP Repeat Peptidase_M49 PF03571.15 GAM17970.1 - 6.2e-223 741.2 0.0 7.7e-223 740.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 ERG4_ERG24 PF01222.17 GAM17971.1 - 1.3e-128 429.5 19.2 1.6e-128 429.2 19.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 GAM17971.1 - 0.0013 18.3 1.6 0.0013 18.3 1.6 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) Yippee-Mis18 PF03226.14 GAM17972.1 - 5e-13 49.2 2.8 5.6e-13 49.0 2.8 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MazG_C PF18722.1 GAM17972.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 MazG C-terminal domain RRM_1 PF00076.22 GAM17973.1 - 3.6e-08 33.1 0.1 7.9e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 GAM17973.1 - 9.5e-06 25.8 0.1 9.5e-06 25.8 0.1 2.2 2 0 0 2 2 2 1 PWI domain Nup35_RRM_2 PF14605.6 GAM17973.1 - 0.091 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HSP20 PF00011.21 GAM17974.1 - 2.1e-14 53.5 1.1 4e-14 52.6 1.1 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM17974.1 - 7.5e-05 22.2 0.0 0.00017 21.1 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF5611 PF18446.1 GAM17974.1 - 0.076 13.9 2.8 0.16 12.8 0.8 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF5611) CS PF04969.16 GAM17974.1 - 0.11 13.5 5.6 0.17 12.9 1.3 2.5 2 1 0 2 2 2 0 CS domain DUF747 PF05346.11 GAM17975.1 - 4.4e-99 331.9 14.4 5.8e-99 331.6 14.4 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family PMP1_2 PF08114.11 GAM17975.1 - 4.8 7.0 5.7 11 5.9 5.7 1.5 1 0 0 1 1 1 0 ATPase proteolipid family Cyclin PF08613.11 GAM17976.1 - 1.6e-21 77.3 10.7 1.6e-21 77.3 10.7 4.0 3 2 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 GAM17976.1 - 7e-08 32.3 0.1 7e-08 32.3 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF3546 PF12066.8 GAM17977.1 - 3.2e-25 88.5 8.3 3.2e-25 88.5 8.3 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 GAM17977.1 - 4.1e-18 66.5 0.6 4.1e-18 66.5 0.6 2.7 3 0 0 3 3 3 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 GAM17977.1 - 1.5e-09 37.5 2.3 4.2e-09 36.1 2.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_1 PF00076.22 GAM17977.1 - 3.1e-06 26.9 0.0 8e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.7 GAM17977.1 - 0.0043 17.4 2.0 0.0043 17.4 2.0 3.1 3 1 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAM17977.1 - 1.6 9.8 4.9 3.7 8.7 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM17977.1 - 1.8 8.9 6.9 0.16 12.3 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TEX19 PF15553.6 GAM17977.1 - 3.9 7.4 7.4 3.3 7.6 0.2 2.8 2 0 0 2 2 2 0 Testis-expressed protein 19 UQ_con PF00179.26 GAM17978.1 - 4.7e-52 175.4 0.1 5.2e-52 175.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM17978.1 - 0.00026 20.7 0.0 0.0003 20.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAM17978.1 - 0.016 15.5 0.2 0.028 14.7 0.2 1.5 1 1 0 1 1 1 0 RWD domain AAA_5 PF07728.14 GAM17979.1 - 3.3e-118 390.0 0.0 1.9e-22 79.8 0.0 8.6 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 GAM17979.1 - 4e-56 187.7 3.0 2.4e-20 72.7 0.1 5.8 6 0 0 6 6 5 4 Midasin AAA lid domain AAA_3 PF07726.11 GAM17979.1 - 9.8e-33 112.8 0.0 3.6e-11 43.1 0.0 7.0 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 GAM17979.1 - 8.2e-31 106.2 0.0 5.6e-30 103.6 0.0 2.6 2 0 0 2 2 1 1 Midasin AAA lid domain AAA_7 PF12775.7 GAM17979.1 - 1.5e-26 93.1 6.8 2.2e-06 27.3 0.3 6.7 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA PF00004.29 GAM17979.1 - 2.6e-24 86.1 1.1 6.8e-05 23.3 0.0 7.2 6 1 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM17979.1 - 4.7e-23 82.4 14.3 1.4e-06 28.8 0.2 7.7 7 2 0 7 7 6 5 AAA ATPase domain Dynein_heavy PF03028.15 GAM17979.1 - 2.8e-19 69.3 0.0 0.02 15.0 0.0 6.7 6 0 0 6 6 5 5 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 GAM17979.1 - 3.3e-17 63.1 0.1 0.0044 17.3 0.0 6.9 6 0 0 6 6 5 4 AAA domain AAA_14 PF13173.6 GAM17979.1 - 3.5e-17 62.7 0.0 0.0034 17.4 0.0 6.7 7 0 0 7 7 6 3 AAA domain Sigma54_activat PF00158.26 GAM17979.1 - 2.7e-16 59.7 0.1 0.0094 15.7 0.0 6.0 5 1 0 5 5 5 3 Sigma-54 interaction domain AAA_6 PF12774.7 GAM17979.1 - 6.4e-14 51.7 0.1 0.21 10.5 0.0 8.4 9 1 0 9 9 8 3 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 GAM17979.1 - 2e-13 50.4 1.7 0.092 12.7 0.0 5.7 5 0 0 5 5 5 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 GAM17979.1 - 1.3e-12 47.4 0.2 0.00088 18.6 0.0 5.0 5 0 0 5 5 5 3 Zeta toxin AAA_18 PF13238.6 GAM17979.1 - 2.1e-12 47.7 1.3 0.25 11.9 0.0 5.9 6 0 0 6 6 4 3 AAA domain AAA_30 PF13604.6 GAM17979.1 - 4.4e-11 42.9 0.1 0.066 12.9 0.0 7.2 7 2 0 7 7 7 1 AAA domain ABC_tran PF00005.27 GAM17979.1 - 5.3e-11 43.2 3.0 0.042 14.4 0.0 5.7 5 0 0 5 5 5 2 ABC transporter AAA_33 PF13671.6 GAM17979.1 - 1.9e-10 41.0 0.5 0.52 10.5 0.0 5.7 7 0 0 7 7 4 2 AAA domain NACHT PF05729.12 GAM17979.1 - 9.9e-10 38.6 0.7 0.48 10.3 0.0 5.5 6 0 0 6 6 5 3 NACHT domain T2SSE PF00437.20 GAM17979.1 - 1.9e-09 37.0 10.5 0.014 14.5 0.0 6.0 6 0 0 6 6 6 3 Type II/IV secretion system protein RNA_helicase PF00910.22 GAM17979.1 - 5.7e-09 36.3 0.2 0.25 11.7 0.0 5.7 5 0 0 5 5 5 1 RNA helicase Mg_chelatase PF01078.21 GAM17979.1 - 2.8e-08 33.4 0.1 7.2 5.9 0.1 8.0 10 0 0 10 10 9 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 GAM17979.1 - 4.7e-08 33.2 0.4 0.053 13.6 0.0 5.0 5 0 0 5 5 3 2 Sigma-54 interaction domain RsgA_GTPase PF03193.16 GAM17979.1 - 5e-08 33.0 4.2 0.4 10.6 0.2 5.1 5 0 0 5 5 4 3 RsgA GTPase AAA_29 PF13555.6 GAM17979.1 - 6.6e-08 32.2 0.7 6.7 6.5 0.0 5.6 5 0 0 5 5 5 0 P-loop containing region of AAA domain AAA_28 PF13521.6 GAM17979.1 - 1e-07 32.3 2.8 0.87 9.8 0.1 5.1 5 0 0 5 5 4 1 AAA domain DUF815 PF05673.13 GAM17979.1 - 1e-07 31.4 0.3 0.31 10.2 0.0 4.9 5 0 0 5 5 5 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 GAM17979.1 - 1.7e-07 31.1 0.9 0.51 10.1 0.0 6.0 6 0 0 6 6 6 1 IstB-like ATP binding protein RuvB_N PF05496.12 GAM17979.1 - 7.7e-07 29.0 2.2 0.69 9.6 0.0 6.3 6 0 0 6 6 6 1 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 GAM17979.1 - 1e-06 29.4 4.8 1.6 9.2 1.4 5.7 5 1 0 5 5 5 1 AAA domain PduV-EutP PF10662.9 GAM17979.1 - 1.5e-06 28.0 3.8 2 8.1 0.0 5.9 6 0 0 6 6 5 2 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 GAM17979.1 - 1.6e-06 27.9 2.2 0.25 11.0 0.0 5.3 6 0 0 6 6 6 1 SRP54-type protein, GTPase domain Rad17 PF03215.15 GAM17979.1 - 3.1e-06 27.2 4.4 5.7 6.8 0.0 6.6 7 0 0 7 7 6 0 Rad17 P-loop domain AAA_8 PF12780.7 GAM17979.1 - 4.2e-06 26.3 2.5 7.5 5.8 0.0 5.9 6 0 0 6 6 6 0 P-loop containing dynein motor region D4 ATPase_2 PF01637.18 GAM17979.1 - 1.1e-05 25.5 0.8 2.9 7.7 0.2 4.9 4 1 0 4 4 4 0 ATPase domain predominantly from Archaea cobW PF02492.19 GAM17979.1 - 1.7e-05 24.5 1.6 0.84 9.2 0.1 4.2 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 GAM17979.1 - 1.8e-05 25.1 3.2 1.7 8.9 0.0 5.5 6 0 0 6 6 4 1 AAA domain MCM PF00493.23 GAM17979.1 - 2.4e-05 23.5 0.0 4.8 6.2 0.0 5.8 7 0 0 7 7 6 0 MCM P-loop domain AAA_11 PF13086.6 GAM17979.1 - 3.3e-05 23.8 2.4 1.3 8.8 0.2 5.0 5 1 0 5 5 4 1 AAA domain Roc PF08477.13 GAM17979.1 - 5.4e-05 23.4 0.9 4.1 7.7 0.0 5.5 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 GAM17979.1 - 5.9e-05 22.9 0.0 3.4 7.3 0.0 4.6 5 0 0 5 5 4 0 AAA domain ATPase PF06745.13 GAM17979.1 - 6.3e-05 22.4 0.9 6.7 6.0 0.0 4.9 5 0 0 5 5 5 0 KaiC AAA_25 PF13481.6 GAM17979.1 - 6.4e-05 22.6 1.2 39 3.7 0.0 5.8 6 0 0 6 6 6 0 AAA domain TIP49 PF06068.13 GAM17979.1 - 0.0001 21.6 1.7 0.19 10.9 0.1 3.7 4 0 0 4 4 4 1 TIP49 P-loop domain AAA_9 PF12781.7 GAM17979.1 - 0.00013 21.1 0.0 0.57 9.3 0.0 4.8 5 0 0 5 5 5 1 ATP-binding dynein motor region Viral_helicase1 PF01443.18 GAM17979.1 - 0.00014 21.7 0.0 1.6 8.4 0.0 4.1 4 0 0 4 4 3 1 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 GAM17979.1 - 0.00016 21.7 0.7 5.3 7.2 0.1 4.8 4 0 0 4 4 4 0 50S ribosome-binding GTPase TniB PF05621.11 GAM17979.1 - 0.0002 20.8 0.3 15 4.9 0.0 5.2 5 0 0 5 5 5 0 Bacterial TniB protein dNK PF01712.19 GAM17979.1 - 0.00024 21.0 3.0 4.7 7.0 0.1 4.6 4 0 0 4 4 4 0 Deoxynucleoside kinase CPT PF07931.12 GAM17979.1 - 0.00024 21.0 2.5 5.8 6.7 0.0 6.1 6 1 0 6 6 5 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 GAM17979.1 - 0.00025 21.1 3.7 0.17 11.9 0.7 4.7 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 GAM17979.1 - 0.00052 20.0 4.2 4.6 7.1 0.1 4.7 4 0 0 4 4 4 0 NTPase KAP_NTPase PF07693.14 GAM17979.1 - 0.001 18.4 0.0 7.5 5.7 0.0 3.9 4 0 0 4 4 4 0 KAP family P-loop domain ATP-synt_ab PF00006.25 GAM17979.1 - 0.0062 16.2 0.0 8.5 6.0 0.0 3.9 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain SRPRB PF09439.10 GAM17979.1 - 0.0068 15.9 3.5 29 4.0 0.0 5.2 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit IPT PF01745.16 GAM17979.1 - 0.013 14.9 0.2 35 3.7 0.0 4.0 4 0 0 4 4 4 0 Isopentenyl transferase TrwB_AAD_bind PF10412.9 GAM17979.1 - 0.022 13.7 0.4 5.7 5.7 0.0 3.7 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain Thymidylate_kin PF02223.17 GAM17979.1 - 0.023 14.4 0.8 3.6 7.2 0.1 3.6 4 0 0 4 4 3 0 Thymidylate kinase ATP_bind_1 PF03029.17 GAM17979.1 - 0.036 13.9 2.6 26 4.5 0.0 4.4 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.9 GAM17979.1 - 0.043 13.1 1.2 23 4.0 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.15 GAM17979.1 - 0.047 13.0 0.2 0.87 8.9 0.0 3.0 3 0 0 3 3 2 0 DnaB-like helicase C terminal domain Bac_DnaA PF00308.18 GAM17979.1 - 0.054 13.3 0.2 12 5.6 0.0 3.3 3 0 0 3 3 3 0 Bacterial dnaA protein DUF87 PF01935.17 GAM17979.1 - 0.097 12.7 0.1 4 7.5 0.0 3.0 2 0 0 2 2 2 0 Helicase HerA, central domain DUF4487 PF14868.6 GAM17979.1 - 0.21 10.4 5.3 2.8 6.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4487) AAA_15 PF13175.6 GAM17979.1 - 5.9 6.5 8.7 2 8.0 3.4 3.0 3 1 1 4 4 2 0 AAA ATPase domain AAA_5 PF07728.14 GAM17980.1 - 2.1e-06 27.8 0.0 1e-05 25.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 GAM17980.1 - 0.0022 18.1 0.0 0.011 15.8 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain NLRC4_HD PF17889.1 GAM17980.1 - 0.0098 16.2 2.0 0.86 10.0 0.3 4.4 3 0 0 3 3 3 1 NLRC4 helical domain VWA_2 PF13519.6 GAM17981.1 - 0.012 16.2 0.1 0.033 14.8 0.1 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain NnrU PF07298.11 GAM17983.1 - 0.065 12.7 5.6 0.039 13.5 3.5 1.7 2 0 0 2 2 2 0 NnrU protein Ost5 PF05251.12 GAM17983.1 - 6.1 7.2 6.6 15 5.9 0.0 3.4 4 0 0 4 4 4 0 Oligosaccharyltransferase subunit 5 Folliculin PF11704.8 GAM17984.1 - 7.9e-06 25.9 0.5 7.9e-06 25.9 0.5 3.2 3 1 0 3 3 3 1 Vesicle coat protein involved in Golgi to plasma membrane transport zf-rbx1 PF12678.7 GAM17985.1 - 4.9e-05 23.5 1.1 0.0001 22.5 1.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAM17985.1 - 0.0014 19.0 1.2 0.0025 18.1 1.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAM17985.1 - 0.0038 17.1 0.7 0.0061 16.4 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA-ATPase_like PF09820.9 GAM17985.1 - 0.011 15.2 1.6 0.016 14.7 1.6 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase Prok-RING_4 PF14447.6 GAM17985.1 - 0.014 15.2 0.4 0.03 14.2 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PBP1_TM PF14812.6 GAM17985.1 - 0.024 15.0 11.0 0.04 14.3 11.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C3HC4_2 PF13923.6 GAM17985.1 - 0.046 13.6 1.6 0.09 12.6 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM17985.1 - 0.049 13.5 2.2 0.1 12.5 2.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PPP4R2 PF09184.11 GAM17985.1 - 0.15 11.7 4.1 0.18 11.3 4.1 1.1 1 0 0 1 1 1 0 PPP4R2 YojJ PF10372.9 GAM17985.1 - 0.34 11.0 2.5 2.7 8.2 0.3 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF3763 PF12592.8 GAM17985.1 - 0.36 10.9 1.3 5.7 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) DUF2046 PF09755.9 GAM17986.1 - 6.5e-23 81.4 41.1 1.3e-22 80.4 29.7 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) ATG16 PF08614.11 GAM17986.1 - 0.00043 20.6 11.7 0.00043 20.6 11.7 2.3 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) MetW PF07021.12 GAM17986.1 - 0.09 12.4 2.6 0.22 11.1 2.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Med13_C PF06333.12 GAM17986.1 - 0.48 9.6 4.5 0.18 11.1 0.2 2.1 1 1 2 3 3 3 0 Mediator complex subunit 13 C-terminal domain RRF_GI PF12614.8 GAM17986.1 - 3.3 7.9 15.6 0.83 9.8 3.8 2.6 1 1 1 2 2 2 0 Ribosome recycling factor Methyltransf_11 PF08241.12 GAM17987.1 - 3.9e-16 59.5 0.0 6.6e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM17987.1 - 2.4e-11 44.2 0.0 8.2e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM17987.1 - 4.7e-09 36.9 0.0 1.1e-08 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM17987.1 - 1.7e-07 31.2 0.0 2.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM17987.1 - 5.9e-07 29.4 0.3 6.1e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM17987.1 - 2.7e-06 26.9 0.0 1.8e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 GAM17987.1 - 0.0023 17.8 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase NodS PF05401.11 GAM17987.1 - 0.011 15.4 0.0 0.034 13.8 0.0 1.8 1 1 0 1 1 1 0 Nodulation protein S (NodS) MetW PF07021.12 GAM17987.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 GAM17987.1 - 0.2 11.2 0.1 1.2 8.7 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase small domain DcuA_DcuB PF03605.14 GAM17987.1 - 0.27 10.1 0.0 0.38 9.6 0.0 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter FNIP PF05725.12 GAM17989.1 - 2.9e-83 273.8 25.5 4e-11 42.9 0.0 12.1 9 1 4 13 13 13 12 FNIP Repeat DUF1769 PF08588.10 GAM17989.1 - 0.033 14.4 10.9 7.5 6.8 0.1 6.9 5 2 4 9 9 9 0 Protein of unknown function (DUF1769) GyrI-like PF06445.15 GAM17990.1 - 7.7e-29 101.0 0.0 8.6e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 GAM17990.1 - 4e-07 30.3 0.0 4.6e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Integron-associated effector binding protein DUF3527 PF12043.8 GAM17991.1 - 0.0096 15.5 0.9 0.015 14.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3527) E1-E2_ATPase PF00122.20 GAM17992.1 - 9.2e-35 119.8 2.5 4e-34 117.7 1.4 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM17992.1 - 3.1e-16 60.3 0.1 1.5e-15 58.1 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM17992.1 - 1.2e-14 53.7 0.0 3.5e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 GAM17992.1 - 1.6e-14 54.0 10.1 1.6e-14 54.0 10.1 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GAM17992.1 - 4.5e-07 29.9 0.0 9.8e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM17992.1 - 0.0021 17.9 0.2 0.058 13.1 0.1 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAM17992.1 - 0.0026 18.2 0.2 0.062 13.7 0.0 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2768 PF10966.8 GAM17992.1 - 0.034 14.6 1.1 0.14 12.6 1.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) EF-hand_6 PF13405.6 GAM17993.1 - 5.9e-12 44.5 0.0 0.00022 20.9 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 GAM17993.1 - 6e-12 45.8 0.0 4.7e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAM17993.1 - 8.4e-11 40.6 0.0 0.0036 16.8 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 GAM17993.1 - 2.1e-10 39.6 0.0 0.001 18.4 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 GAM17993.1 - 2.5e-06 27.3 0.1 0.00088 19.1 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair Secretin_N PF03958.17 GAM17993.1 - 0.099 13.1 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Aa_trans PF01490.18 GAM17994.1 - 1.3e-54 185.6 29.2 1.5e-54 185.3 29.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Acetyltransf_1 PF00583.25 GAM17997.1 - 8.1e-12 45.4 0.0 0.017 15.4 0.0 4.6 4 0 0 4 4 4 3 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM17997.1 - 9.8e-10 38.7 0.2 0.031 14.7 0.0 4.4 4 0 0 4 4 4 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM17997.1 - 6.8e-08 32.5 0.0 1.8 8.8 0.0 4.8 5 0 0 5 5 5 3 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 GAM17997.1 - 1.3e-05 25.2 0.5 11 5.9 0.0 5.1 5 0 0 5 5 5 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM17997.1 - 0.0058 16.6 1.5 20 5.3 0.0 4.8 6 0 0 6 6 6 2 FR47-like protein Acetyltransf_15 PF17013.5 GAM17997.1 - 0.041 13.4 0.2 39 3.6 0.0 4.1 4 0 0 4 4 4 0 Putative acetyl-transferase Pkinase PF00069.25 GAM17998.1 - 4.2e-69 232.8 0.0 5e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM17998.1 - 2.1e-31 109.2 0.0 3.9e-31 108.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM17998.1 - 3.4e-06 26.6 0.3 0.02 14.2 0.0 2.3 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 GAM17998.1 - 0.00039 20.1 1.3 0.00083 19.0 1.3 1.4 1 1 0 1 1 1 1 RIO1 family RhoGAP PF00620.27 GAM17999.1 - 9.4e-33 113.2 0.3 2e-32 112.1 0.3 1.5 1 0 0 1 1 1 1 RhoGAP domain COBRA1 PF06209.13 GAM17999.1 - 0.099 11.5 0.2 0.17 10.7 0.2 1.3 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) Choline_kinase PF01633.20 GAM18000.1 - 3.7e-64 216.2 0.0 7.2e-64 215.3 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 GAM18000.1 - 1.5e-10 41.4 0.0 2.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAM18000.1 - 0.00061 19.2 0.2 0.012 14.9 0.3 2.2 1 1 1 2 2 2 2 Ecdysteroid kinase Kdo PF06293.14 GAM18000.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spc42p PF11544.8 GAM18001.1 - 0.021 14.8 1.3 0.037 14.0 1.3 1.4 1 0 0 1 1 1 0 Spindle pole body component Spc42p zf-C3HC4_3 PF13920.6 GAM18002.1 - 6.4e-09 35.5 9.2 1.1e-08 34.8 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM18002.1 - 5.3e-08 32.6 8.0 1e-07 31.7 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM18002.1 - 5.1e-06 26.3 10.4 1.1e-05 25.2 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM18002.1 - 7.2e-06 25.8 8.3 1.3e-05 25.0 8.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAM18002.1 - 5e-05 23.2 9.0 0.00011 22.0 9.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM18002.1 - 8.3e-05 22.5 6.3 0.00017 21.5 6.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAM18002.1 - 0.00018 21.8 9.1 0.00033 20.9 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain DUF4201 PF13870.6 GAM18002.1 - 0.0013 18.5 20.2 0.0013 18.5 20.2 7.6 3 3 3 7 7 6 1 Domain of unknown function (DUF4201) zf-rbx1 PF12678.7 GAM18002.1 - 0.004 17.4 5.0 0.01 16.1 5.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 GAM18002.1 - 0.0049 16.7 3.3 0.012 15.5 3.3 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 GAM18002.1 - 0.03 14.1 9.6 0.063 13.1 9.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 GAM18002.1 - 0.042 13.9 2.3 0.088 12.9 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Spc7 PF08317.11 GAM18002.1 - 0.14 11.0 101.1 0.12 11.2 2.2 6.4 2 1 4 6 6 6 0 Spc7 kinetochore protein zf-C3HC4_4 PF15227.6 GAM18002.1 - 0.24 11.6 7.9 0.52 10.5 7.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SSP160 PF06933.11 GAM18002.1 - 0.73 8.0 13.5 1.1 7.4 13.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 GAM18002.1 - 0.81 9.7 19.7 1.9 8.5 19.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 GAM18002.1 - 0.84 9.6 14.3 2.5 8.1 14.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-Nse PF11789.8 GAM18002.1 - 1.7 8.5 5.2 4.4 7.2 5.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_MLP1_2 PF07926.12 GAM18002.1 - 3.7 7.6 103.2 0.02 14.9 2.2 6.5 4 2 2 6 6 6 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.25 GAM18003.1 - 1.5e-50 172.1 0.2 1.1e-49 169.2 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18003.1 - 7.7e-21 74.5 0.0 1.3e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM18003.1 - 0.046 13.6 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Herpes_UL52 PF03121.15 GAM18005.1 - 1.2e-08 34.7 0.0 3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase DUF1779 PF08680.10 GAM18005.1 - 0.72 10.0 8.7 0.78 9.9 7.0 1.9 2 0 0 2 2 2 0 TATA-box binding SKICH PF17751.1 GAM18006.1 - 5.3e-13 49.4 2.8 0.001 19.6 0.1 4.1 3 0 0 3 3 3 3 SKICH domain HECW_N PF16562.5 GAM18006.1 - 5.6e-10 39.1 0.0 0.0043 16.8 0.0 3.4 3 0 0 3 3 3 3 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 CUE PF02845.16 GAM18006.1 - 0.0001 21.9 0.2 0.0003 20.4 0.2 1.8 1 0 0 1 1 1 1 CUE domain fn3_PAP PF17808.1 GAM18006.1 - 0.003 17.6 0.4 12 6.1 0.0 3.9 3 1 1 4 4 4 1 Fn3-like domain from Purple Acid Phosphatase Myosin_head PF00063.21 GAM18007.1 - 3.7e-158 527.8 21.7 3.7e-158 527.8 21.7 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) MyTH4 PF00784.17 GAM18007.1 - 3.6e-50 169.0 10.5 6.7e-29 100.5 0.0 4.2 4 0 0 4 4 4 2 MyTH4 domain FERM_M PF00373.18 GAM18007.1 - 1.4e-21 77.1 13.1 1.8e-11 44.5 0.0 3.7 3 0 0 3 3 3 2 FERM central domain SH3_2 PF07653.17 GAM18007.1 - 1.9e-11 43.5 0.0 8.1e-11 41.4 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 GAM18007.1 - 1.9e-08 34.0 0.0 1.1e-07 31.6 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain RA PF00788.23 GAM18007.1 - 2.3e-07 31.3 0.0 2.1e-05 25.0 0.0 2.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain IQ PF00612.27 GAM18007.1 - 4.7e-07 29.0 16.4 0.00066 19.2 0.3 4.4 4 0 0 4 4 4 2 IQ calmodulin-binding motif SH3_1 PF00018.28 GAM18007.1 - 1.3e-06 27.9 0.0 3.5e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 SH3 domain FERM_N PF09379.10 GAM18007.1 - 0.094 12.7 0.1 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 FERM N-terminal domain AviRa PF11599.8 GAM18008.1 - 0.047 13.1 0.2 0.09 12.2 0.2 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Voldacs PF03517.13 GAM18009.1 - 9.3e-17 61.5 30.1 1.4e-15 57.6 30.1 2.6 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 GAM18009.1 - 0.081 13.1 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 EGF PF00008.27 GAM18012.1 - 0.00016 21.9 23.8 0.001 19.3 7.8 2.6 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 GAM18012.1 - 0.00023 21.5 28.9 0.016 15.6 9.8 2.5 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 GAM18012.1 - 0.42 11.3 25.9 0.071 13.8 8.1 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.27 GAM18013.1 - 0.00067 19.9 25.3 0.03 14.6 9.1 2.7 2 0 0 2 2 2 2 EGF-like domain EGF_2 PF07974.13 GAM18013.1 - 1.2 9.5 35.8 0.23 11.8 12.5 2.7 3 0 0 3 3 3 0 EGF-like domain EB PF01683.18 GAM18013.1 - 8.1 6.8 27.3 0.029 14.6 6.5 2.8 2 1 1 3 3 3 0 EB module His_Phos_1 PF00300.22 GAM18015.1 - 3.7e-29 101.8 0.7 7.6e-29 100.8 0.7 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UCH PF00443.29 GAM18016.1 - 2e-35 122.6 0.5 2e-35 122.6 0.5 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAM18016.1 - 3e-13 49.9 4.2 6.3e-13 48.8 4.2 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 GAM18016.1 - 0.26 11.1 3.5 0.65 9.8 3.5 1.7 1 0 0 1 1 1 0 Variant UBP zinc finger Pkinase PF00069.25 GAM18017.1 - 1.8e-06 27.6 0.0 1.8e-06 27.6 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Mt_ATP-synt_B PF05405.14 GAM18017.1 - 0.0099 15.5 2.7 0.0099 15.5 2.7 2.3 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FliD_N PF02465.18 GAM18017.1 - 0.029 15.0 1.3 0.029 15.0 1.3 2.9 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus UPF0449 PF15136.6 GAM18017.1 - 1.3 9.6 11.7 0.31 11.6 3.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 AI-2E_transport PF01594.16 GAM18017.1 - 3.5 6.7 6.3 0.47 9.6 0.9 2.0 2 0 0 2 2 2 0 AI-2E family transporter DUF4355 PF14265.6 GAM18017.1 - 4.2 7.6 13.1 5.6 7.2 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) RGS PF00615.19 GAM18018.1 - 3.4e-24 85.4 0.9 5.5e-23 81.5 0.9 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain SOG2 PF10428.9 GAM18018.1 - 0.00028 20.2 9.6 0.00032 20.0 9.6 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein ORC6 PF05460.13 GAM18018.1 - 0.037 13.3 6.4 0.044 13.1 6.4 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SPX PF03105.19 GAM18018.1 - 0.1 12.5 9.0 0.13 12.2 9.0 1.1 1 0 0 1 1 1 0 SPX domain Dicty_REP PF05086.12 GAM18018.1 - 0.22 9.4 10.1 0.29 9.1 10.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Menin PF05053.13 GAM18018.1 - 0.4 9.0 5.9 0.52 8.6 5.9 1.1 1 0 0 1 1 1 0 Menin Hamartin PF04388.12 GAM18018.1 - 0.66 8.6 8.0 0.79 8.3 8.0 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 GAM18018.1 - 1.4 7.4 9.7 1.7 7.1 9.7 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 GAM18018.1 - 1.7 7.4 8.8 2.3 7.0 8.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3439 PF11921.8 GAM18018.1 - 4.9 7.2 14.0 8.2 6.4 14.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Kelch_4 PF13418.6 GAM18019.1 - 5e-42 141.7 15.6 5.5e-08 32.7 0.2 7.1 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM18019.1 - 1.4e-28 98.6 19.9 3.2e-06 27.3 0.0 7.0 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM18019.1 - 5.5e-26 90.1 13.2 1.1e-06 28.5 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 GAM18019.1 - 3.1e-23 81.1 16.1 4.4e-05 23.0 0.0 6.8 6 1 1 7 7 7 5 Kelch motif Kelch_6 PF13964.6 GAM18019.1 - 3.3e-21 74.8 10.5 7.7e-06 26.0 0.1 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 GAM18019.1 - 1.4e-15 56.5 16.2 1.8e-05 24.5 0.2 6.4 6 1 0 6 6 6 5 Kelch motif zf-C3HC4_3 PF13920.6 GAM18019.1 - 2.1e-12 46.7 11.9 3.9e-12 45.8 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM18019.1 - 7.6e-05 22.5 12.6 0.00015 21.5 12.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 K-box PF01486.17 GAM18019.1 - 0.0012 19.0 5.4 0.0012 19.0 5.4 4.3 3 1 1 4 4 4 1 K-box region DUF2039 PF10217.9 GAM18019.1 - 0.063 13.6 3.2 0.19 12.1 3.2 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) FlaC_arch PF05377.11 GAM18019.1 - 0.2 12.1 11.4 4 7.9 0.9 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TFIIA PF03153.13 GAM18019.1 - 1.1 9.2 31.2 1.6 8.6 31.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Beach PF02138.18 GAM18020.1 - 1.5e-123 411.5 0.1 2.8e-123 410.7 0.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 GAM18020.1 - 1.1e-54 185.6 2.1 1.1e-54 185.6 2.1 5.6 4 2 1 5 5 5 2 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 GAM18020.1 - 5.1e-25 87.5 0.0 1.8e-24 85.7 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 GAM18020.1 - 1.6e-15 57.2 12.9 1.5e-06 28.8 0.1 6.4 6 0 0 6 6 5 3 WD domain, G-beta repeat Laminin_G_3 PF13385.6 GAM18020.1 - 1.9e-14 54.1 0.0 4.9e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 GAM18020.1 - 3.1e-13 49.6 4.6 4.8e-13 49.0 0.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) ANAPC4_WD40 PF12894.7 GAM18020.1 - 0.00022 21.4 1.2 4.9 7.5 0.1 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1088 PF06469.11 GAM18020.1 - 0.0011 18.7 0.5 0.0033 17.1 0.5 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) Xpo1 PF08389.12 GAM18020.1 - 0.0025 17.9 1.4 0.0025 17.9 1.4 3.9 3 1 1 4 4 4 1 Exportin 1-like protein TIP120 PF08623.10 GAM18020.1 - 0.053 13.3 4.0 1.2 8.9 0.6 2.9 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) ATPase_2 PF01637.18 GAM18020.1 - 0.1 12.5 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Peptidase_M8 PF01457.16 GAM18021.1 - 7.9e-45 153.5 0.3 1.2e-44 152.9 0.3 1.2 1 0 0 1 1 1 1 Leishmanolysin Ank_4 PF13637.6 GAM18022.1 - 4.1e-28 97.4 5.8 6.6e-08 33.0 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM18022.1 - 1.8e-23 82.9 4.1 2.2e-12 47.4 0.9 4.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAM18022.1 - 1.7e-20 72.5 5.5 0.0016 18.8 0.0 7.3 6 1 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 GAM18022.1 - 7.4e-16 56.7 12.8 0.00016 21.8 0.1 8.2 6 2 1 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 GAM18022.1 - 1.4e-09 38.0 4.5 0.00011 22.4 0.2 5.4 4 2 1 5 5 5 3 Ankyrin repeats (many copies) F-box-like PF12937.7 GAM18022.1 - 3e-07 30.2 3.4 7.8e-07 28.9 3.4 1.7 1 0 0 1 1 1 1 F-box-like SH2 PF00017.24 GAM18022.1 - 4.8e-07 29.8 0.0 1.6e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 SH2 domain F-box PF00646.33 GAM18022.1 - 2.4e-06 27.2 3.8 6.7e-06 25.8 3.8 1.8 1 0 0 1 1 1 1 F-box domain SH2_2 PF14633.6 GAM18022.1 - 0.011 15.2 0.1 0.052 12.9 0.0 2.1 2 0 0 2 2 2 0 SH2 domain F-box_4 PF15966.5 GAM18022.1 - 0.024 14.5 1.2 0.052 13.4 1.2 1.5 1 0 0 1 1 1 0 F-box GHMP_kinases_N PF00288.26 GAM18023.1 - 4.4e-17 62.1 0.0 1.1e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAM18023.1 - 7.1e-05 23.1 0.0 0.00017 21.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal PLDc PF00614.22 GAM18024.1 - 4e-19 68.0 7.7 8.6e-10 38.4 0.5 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GAM18024.1 - 6.4e-14 52.0 2.4 2.8e-08 33.7 0.9 2.8 2 1 0 2 2 2 2 PLD-like domain Nsp3_PL2pro PF12124.8 GAM18024.1 - 0.052 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain CBM49 PF09478.10 GAM18025.1 - 4e-17 62.3 0.0 5.6e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Taxilin PF09728.9 GAM18027.1 - 0.00058 19.1 7.1 0.0008 18.7 7.1 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein FadA PF09403.10 GAM18027.1 - 0.025 15.1 0.5 0.025 15.1 0.5 2.3 1 1 1 2 2 2 0 Adhesion protein FadA DUF1027 PF06265.11 GAM18027.1 - 0.072 13.1 0.3 0.15 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) EzrA PF06160.12 GAM18027.1 - 0.26 9.4 10.9 0.17 10.0 6.0 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Takusan PF04822.13 GAM18027.1 - 1.3 8.9 13.8 0.2 11.6 1.9 3.3 2 1 1 3 3 3 0 Takusan DUF1664 PF07889.12 GAM18027.1 - 2.7 8.1 7.5 6.3 6.9 3.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GAM18027.1 - 3.4 7.9 6.8 6.3 7.0 3.6 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 GAM18027.1 - 4.2 7.2 6.9 34 4.3 0.0 3.2 2 1 1 3 3 3 0 Septum formation initiator FAM76 PF16046.5 GAM18027.1 - 6.5 6.0 17.5 0.014 14.8 5.8 2.3 2 1 0 2 2 2 0 FAM76 protein Macoilin PF09726.9 GAM18027.1 - 7.7 4.9 27.8 0.035 12.7 13.1 2.1 1 1 1 2 2 2 0 Macoilin family Phospholip_B PF04916.13 GAM18028.1 - 1.6e-177 591.3 4.7 1.9e-177 591.1 4.7 1.0 1 0 0 1 1 1 1 Phospholipase B FNIP PF05725.12 GAM18029.1 - 8.4e-67 221.1 16.6 1.9e-13 50.3 0.1 9.2 6 2 3 10 10 10 8 FNIP Repeat F-box PF00646.33 GAM18029.1 - 0.018 14.9 0.8 0.06 13.3 0.8 1.9 1 0 0 1 1 1 0 F-box domain zf-RING_4 PF14570.6 GAM18030.1 - 1.5e-17 63.1 14.1 2.5e-17 62.4 14.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 GAM18030.1 - 5e-07 29.5 9.3 1e-06 28.5 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 GAM18030.1 - 7.9e-07 28.8 0.2 2.6e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 GAM18030.1 - 1.3e-05 25.4 10.6 2.4e-05 24.6 10.6 1.5 1 0 0 1 1 1 1 Ring finger domain Spore_III_AF PF09581.10 GAM18030.1 - 0.0001 22.4 1.1 0.0001 22.4 1.1 6.5 4 2 2 6 6 6 1 Stage III sporulation protein AF (Spore_III_AF) Rtf2 PF04641.12 GAM18030.1 - 0.00038 19.9 1.9 0.00038 19.9 1.9 6.7 6 1 2 8 8 8 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 GAM18030.1 - 0.068 13.0 8.6 4.1 7.3 9.0 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GAM18030.1 - 0.12 12.3 11.1 0.27 11.2 11.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM18030.1 - 0.24 11.4 10.2 0.55 10.2 10.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM18030.1 - 1.2 9.0 10.1 2.8 7.9 10.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Consortin_C PF15281.6 GAM18032.1 - 0.21 11.6 1.2 0.39 10.7 1.2 1.4 1 0 0 1 1 1 0 Consortin C-terminus DUF900 PF05990.12 GAM18033.1 - 6.8e-24 84.7 0.0 1e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 GAM18033.1 - 0.01 16.5 0.0 0.015 15.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family YwiC PF14256.6 GAM18033.1 - 0.43 10.9 8.2 0.029 14.7 3.0 1.6 2 0 0 2 2 2 0 YwiC-like protein Sulfotransfer_2 PF03567.14 GAM18035.1 - 5.5e-12 46.1 6.7 8.8e-12 45.5 0.3 2.5 2 1 0 2 2 2 2 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 GAM18035.1 - 1.9e-05 23.7 1.4 0.00022 20.2 0.2 2.4 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase Rad51 PF08423.11 GAM18036.1 - 6.9e-127 422.0 0.0 8.4e-127 421.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GAM18036.1 - 5.6e-11 42.4 0.0 8.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 GAM18036.1 - 1.4e-10 41.1 0.0 2.5e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 GAM18036.1 - 1.2e-07 32.2 1.2 2.7e-07 31.1 0.7 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 GAM18036.1 - 1.9e-05 24.2 1.0 0.00014 21.3 1.0 2.2 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 GAM18036.1 - 0.014 14.7 0.2 0.22 10.8 0.1 2.3 1 1 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 GAM18036.1 - 0.036 13.8 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma70_ner PF04546.13 GAM18036.1 - 0.062 13.2 1.4 0.1 12.5 1.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region AAA_28 PF13521.6 GAM18036.1 - 0.19 12.0 0.2 0.19 12.0 0.2 1.7 2 0 0 2 2 2 0 AAA domain Hormone_1 PF00103.20 GAM18037.1 - 0.053 13.3 0.2 0.068 12.9 0.2 1.2 1 0 0 1 1 1 0 Somatotropin hormone family ArfGap PF01412.18 GAM18038.1 - 1e-36 125.6 0.2 1e-36 125.6 0.2 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf LRR_8 PF13855.6 GAM18039.1 - 1.2e-23 82.6 26.1 7.3e-11 41.7 3.1 4.1 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 GAM18039.1 - 6.8e-21 74.0 33.8 1.8e-08 34.5 1.4 5.3 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM18039.1 - 1.2e-07 31.3 22.0 6.4 7.7 0.2 8.2 7 1 1 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 GAM18039.1 - 0.37 11.0 38.1 0.77 10.0 0.1 8.1 8 0 0 8 8 8 0 Leucine Rich repeat ORMDL PF04061.14 GAM18040.1 - 3.8e-43 146.6 2.0 4.2e-43 146.4 2.0 1.0 1 0 0 1 1 1 1 ORMDL family DER1 PF04511.15 GAM18041.1 - 1.8e-49 168.3 9.4 2.1e-49 168.1 9.4 1.0 1 0 0 1 1 1 1 Der1-like family ABC2_membrane PF01061.24 GAM18042.1 - 5e-39 133.9 24.8 5e-39 133.9 24.8 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAM18042.1 - 1.8e-24 86.8 0.0 2.9e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM18042.1 - 2e-10 41.0 1.6 2.4e-06 27.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM18042.1 - 0.001 18.6 0.0 0.11 11.9 0.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAM18042.1 - 0.018 14.9 0.1 0.051 13.5 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase ABC2_membrane_3 PF12698.7 GAM18042.1 - 0.064 12.4 20.8 0.028 13.6 17.4 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 GAM18042.1 - 0.064 12.5 3.6 0.16 11.2 3.6 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_29 PF13555.6 GAM18042.1 - 0.08 12.7 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 GAM18042.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 GAM18042.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAM18042.1 - 0.23 11.8 0.0 0.59 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain EGF PF00008.27 GAM18042.1 - 1.1 9.6 8.1 0.1 13.0 1.9 2.7 2 0 0 2 2 2 0 EGF-like domain NADH-G_4Fe-4S_3 PF10588.9 GAM18042.1 - 6.7 6.3 7.8 5.1 6.7 0.1 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NDK PF00334.19 GAM18043.1 - 8.9e-55 184.4 0.0 1e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 GAM18043.1 - 0.15 12.6 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Nup192 PF11894.8 GAM18044.1 - 4.5e-69 233.0 43.4 3.3e-63 213.6 31.1 3.2 2 1 0 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 FNIP PF05725.12 GAM18045.1 - 2.9e-82 270.6 42.1 2.2e-14 53.3 1.0 11.1 5 3 2 11 11 11 10 FNIP Repeat DUF1769 PF08588.10 GAM18045.1 - 0.0012 19.0 0.4 37 4.6 0.0 5.7 4 1 1 5 5 5 2 Protein of unknown function (DUF1769) Myotub-related PF06602.14 GAM18046.1 - 7e-125 416.6 0.0 1.4e-124 415.7 0.0 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 GAM18046.1 - 0.0072 16.3 1.2 0.015 15.2 0.0 2.1 3 0 0 3 3 3 1 Tyrosine phosphatase family OmpH PF03938.14 GAM18046.1 - 9.7 6.5 17.0 10 6.4 9.0 2.9 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Resolvase PF00239.21 GAM18047.1 - 1.2e-08 35.2 0.1 1.9e-07 31.3 0.0 2.5 3 0 0 3 3 3 1 Resolvase, N terminal domain PapG_C PF03628.13 GAM18048.1 - 0.1 12.5 0.6 0.24 11.3 0.1 1.8 2 0 0 2 2 2 0 PapG chaperone-binding domain SapB_2 PF03489.17 GAM18048.1 - 0.45 10.7 4.1 1.2 9.3 1.0 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 2 Cyclin_N PF00134.23 GAM18049.1 - 4e-16 58.9 3.6 4e-16 58.9 3.6 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAM18049.1 - 0.00047 20.2 0.5 0.95 9.6 0.3 2.9 2 1 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 GAM18049.1 - 0.0074 16.7 0.2 0.044 14.2 0.0 2.3 2 1 0 2 2 2 1 Cyclin C-terminal domain PRP38 PF03371.15 GAM18049.1 - 0.017 15.0 0.4 0.048 13.5 0.4 1.9 1 1 0 1 1 1 0 PRP38 family ATP-synt_C PF00137.21 GAM18050.1 - 5.1e-28 97.2 35.8 1.4e-17 63.8 15.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Response_reg PF00072.24 GAM18051.1 - 2.2e-27 95.5 1.4 7.4e-21 74.4 0.1 3.0 2 1 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 GAM18051.1 - 1.5e-26 93.1 0.2 4e-26 91.7 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAM18051.1 - 5.4e-15 55.2 0.5 1.1e-14 54.1 0.5 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAM18051.1 - 0.014 15.2 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 GAM18051.1 - 0.024 14.6 0.0 0.13 12.2 0.0 2.2 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain Costars PF14705.6 GAM18052.1 - 1.8e-28 98.5 0.5 2e-28 98.4 0.5 1.0 1 0 0 1 1 1 1 Costars ArfGap PF01412.18 GAM18053.1 - 1.9e-27 95.7 0.3 1.9e-27 95.7 0.3 2.2 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf zf_C2HC_14 PF18574.1 GAM18053.1 - 0.0065 16.2 9.7 0.11 12.4 0.6 3.2 3 0 0 3 3 3 2 C2HC Zing finger domain zf_UBZ PF18439.1 GAM18053.1 - 0.0099 15.4 12.9 2.4 7.8 0.0 5.5 4 1 1 5 5 5 2 Ubiquitin-Binding Zinc Finger zf-FCS PF06467.14 GAM18053.1 - 0.061 13.3 4.6 1.2 9.1 0.2 3.6 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-TRAF PF02176.18 GAM18053.1 - 0.088 13.5 9.3 0.1 13.3 5.0 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger TF_Zn_Ribbon PF08271.12 GAM18053.1 - 0.32 10.6 8.5 0.41 10.2 1.6 3.5 3 0 0 3 3 3 0 TFIIB zinc-binding C1_1 PF00130.22 GAM18053.1 - 0.73 9.8 18.5 0.49 10.3 1.0 3.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Di19 PF05605.12 GAM18053.1 - 5.3 7.4 9.1 1.6 9.1 2.5 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.25 GAM18054.1 - 1.5e-70 237.6 0.0 2.4e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18054.1 - 1.8e-44 152.0 0.0 2.8e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 GAM18054.1 - 4.4e-25 87.5 36.1 0.00071 20.3 0.1 9.0 9 0 0 9 9 9 7 WD domain, G-beta repeat PB1 PF00564.24 GAM18054.1 - 3.9e-12 45.9 0.0 6.9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 PB1 domain F-box-like PF12937.7 GAM18054.1 - 8.7e-10 38.3 0.4 1.6e-09 37.5 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM18054.1 - 2e-09 37.1 0.9 4e-09 36.1 0.9 1.5 1 0 0 1 1 1 1 F-box domain Kinase-like PF14531.6 GAM18054.1 - 1.9e-07 30.7 0.2 1.6e-06 27.6 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Nup160 PF11715.8 GAM18054.1 - 0.00011 21.1 14.6 0.25 10.0 1.1 5.4 1 1 1 5 5 5 3 Nucleoporin Nup120/160 Pkinase_fungal PF17667.1 GAM18054.1 - 0.00016 20.6 0.9 0.00023 20.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase ANAPC4_WD40 PF12894.7 GAM18054.1 - 0.00066 19.9 0.8 2.7 8.3 0.0 4.1 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 GAM18054.1 - 5.5 7.1 14.5 0.21 11.7 1.8 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 GAM18055.1 - 5.4e-24 84.6 3.0 5.1e-12 46.2 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM18055.1 - 3.2e-22 78.6 9.8 2.8e-08 34.1 0.3 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM18055.1 - 4.2e-19 68.1 6.3 1.4e-06 28.5 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 GAM18055.1 - 1.6e-18 66.5 2.6 2.4e-09 37.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM18055.1 - 8.4e-17 59.6 2.2 5.2e-06 26.4 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat SAP PF02037.27 GAM18058.1 - 2.3e-10 40.0 2.3 4.9e-10 38.9 2.3 1.6 1 0 0 1 1 1 1 SAP domain CDC45 PF02724.14 GAM18058.1 - 0.0086 14.4 10.6 0.011 14.0 10.6 1.3 1 0 0 1 1 1 1 CDC45-like protein DDHD PF02862.17 GAM18058.1 - 0.016 15.4 3.7 0.02 15.0 3.7 1.3 1 0 0 1 1 1 0 DDHD domain Merozoite_SPAM PF07133.11 GAM18058.1 - 0.057 13.4 35.2 0.11 12.5 35.2 1.6 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) ORC6 PF05460.13 GAM18058.1 - 0.065 12.5 14.0 0.098 11.9 14.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Paf1 PF03985.13 GAM18058.1 - 0.068 12.2 30.5 0.11 11.5 30.5 1.3 1 0 0 1 1 1 0 Paf1 BUD22 PF09073.10 GAM18058.1 - 0.074 12.4 25.6 0.11 11.9 25.6 1.2 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 GAM18058.1 - 0.12 12.4 15.7 0.18 11.8 15.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRN3 PF05327.11 GAM18058.1 - 0.24 9.9 8.7 0.36 9.3 8.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GAM18058.1 - 0.36 9.0 25.3 0.5 8.5 25.3 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 GAM18058.1 - 0.36 10.1 13.2 0.85 8.9 13.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CAC1F_C PF16885.5 GAM18058.1 - 0.42 10.2 11.7 0.78 9.3 11.7 1.4 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term MDM1 PF15501.6 GAM18058.1 - 1 8.5 24.3 1.4 8.0 24.3 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 F-protein PF00469.20 GAM18058.1 - 1 8.9 9.0 2.2 7.8 9.0 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Hamartin PF04388.12 GAM18058.1 - 1.2 7.7 15.7 1.6 7.3 15.7 1.1 1 0 0 1 1 1 0 Hamartin protein CDC27 PF09507.10 GAM18058.1 - 1.4 8.2 32.1 2.3 7.5 32.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 GAM18058.1 - 1.6 8.2 26.6 2.7 7.5 26.6 1.3 1 0 0 1 1 1 0 PPP4R2 HeH PF12949.7 GAM18058.1 - 1.6 8.5 3.9 0.47 10.2 0.3 2.1 2 1 0 2 2 1 0 HeH/LEM domain CobT PF06213.12 GAM18058.1 - 1.8 7.9 22.6 2.8 7.2 22.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4045 PF13254.6 GAM18058.1 - 2.2 7.9 22.4 3.3 7.3 22.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Presenilin PF01080.17 GAM18058.1 - 3.3 6.4 17.7 4.7 5.9 17.7 1.2 1 0 0 1 1 1 0 Presenilin DUF5523 PF17661.1 GAM18058.1 - 4.4 6.9 31.4 3.5 7.2 29.7 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Membralin PF09746.9 GAM18058.1 - 6.8 5.6 9.5 11 4.9 9.4 1.3 1 0 0 1 1 1 0 Tumour-associated protein DUF913 PF06025.12 GAM18058.1 - 7.7 5.4 14.4 15 4.5 14.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2052 PF09747.9 GAM18058.1 - 8.6 6.4 30.5 36 4.4 30.4 2.0 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SdiA-regulated PF06977.11 GAM18060.1 - 0.00079 18.7 0.0 0.0017 17.6 0.0 1.5 1 1 0 1 1 1 1 SdiA-regulated CI-B14_5a PF07347.12 GAM18060.1 - 0.023 14.6 1.1 0.047 13.6 1.1 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) WD40_3 PF15911.5 GAM18060.1 - 0.093 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat PEX11 PF05648.14 GAM18062.1 - 4.5e-55 186.5 3.0 5.2e-55 186.3 3.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ABC2_membrane PF01061.24 GAM18063.1 - 0.0049 16.3 0.6 0.0084 15.5 0.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter DUF1275 PF06912.11 GAM18063.1 - 0.049 13.6 0.9 0.065 13.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Peptidase_S28 PF05577.12 GAM18064.1 - 1.2e-124 416.4 8.3 1.4e-124 416.2 8.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 GAM18064.1 - 7e-05 21.7 0.1 0.00017 20.4 0.1 1.5 2 0 0 2 2 2 1 PS-10 peptidase S37 Epimerase PF01370.21 GAM18065.1 - 7.5e-11 41.9 1.0 2.9e-05 23.6 0.1 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAM18065.1 - 1.3e-05 24.9 0.1 2.7e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 GAM18065.1 - 1.8e-05 23.9 1.5 0.0024 16.9 0.1 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox PF00070.27 GAM18065.1 - 0.00022 21.7 0.1 0.0052 17.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 GAM18065.1 - 0.001 18.6 0.0 0.1 12.0 0.0 2.6 3 1 0 3 3 3 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM18065.1 - 0.0046 16.1 0.3 0.18 10.8 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAM18065.1 - 0.0059 16.5 0.0 0.0095 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 GAM18065.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 GAM18065.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Pyr_redox_2 PF07992.14 GAM18065.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 GAM18065.1 - 0.028 14.6 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.15 GAM18065.1 - 0.031 13.4 0.0 2.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 GAM18065.1 - 0.079 12.8 0.9 0.29 11.0 0.9 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 GAM18065.1 - 0.12 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ETF PF01012.21 GAM18066.1 - 3e-42 144.6 2.8 4.4e-42 144.0 2.8 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 GAM18066.1 - 2.1e-36 123.8 1.0 2.1e-36 123.8 1.0 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain TPP_enzyme_M PF00205.22 GAM18066.1 - 0.18 11.6 1.6 4 7.2 0.4 3.5 2 2 1 3 3 3 0 Thiamine pyrophosphate enzyme, central domain Ras PF00071.22 GAM18067.1 - 4e-23 81.8 0.4 5.5e-23 81.3 0.4 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM18067.1 - 6.4e-09 36.1 1.2 1.2e-08 35.2 1.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM18067.1 - 0.00044 19.8 1.7 0.0014 18.1 1.7 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM18067.1 - 0.0041 17.2 0.1 0.014 15.5 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM18067.1 - 0.0041 17.0 0.1 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase TniB PF05621.11 GAM18067.1 - 0.0042 16.5 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein DUF815 PF05673.13 GAM18067.1 - 0.019 14.1 0.0 0.051 12.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AIG1 PF04548.16 GAM18067.1 - 0.023 14.1 0.2 1.5 8.1 0.1 2.2 2 0 0 2 2 2 0 AIG1 family AAA_7 PF12775.7 GAM18067.1 - 0.025 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 GAM18067.1 - 0.031 14.5 0.2 0.05 13.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAM18067.1 - 0.04 13.9 0.1 0.089 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 GAM18067.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM18067.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain FNIP PF05725.12 GAM18068.1 - 2.6e-87 286.8 22.1 1.1e-12 47.9 2.7 12.8 6 2 5 14 14 14 13 FNIP Repeat CAP_N PF01213.19 GAM18068.1 - 0.98 8.8 9.4 0.019 14.5 2.7 1.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal LCE PF14672.6 GAM18068.1 - 3.1 8.4 19.0 22 5.8 19.0 2.4 1 1 0 1 1 1 0 Late cornified envelope RhoGAP PF00620.27 GAM18069.1 - 5e-31 107.6 4.8 2.1e-30 105.6 0.1 2.8 3 1 0 3 3 3 1 RhoGAP domain FCH PF00611.23 GAM18069.1 - 3.8e-09 36.7 0.5 2.6e-08 34.0 0.5 2.5 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain UvrA_DNA-bind PF17755.1 GAM18069.1 - 0.0057 17.0 0.1 0.013 15.8 0.1 1.6 1 0 0 1 1 1 1 UvrA DNA-binding domain PP28 PF10252.9 GAM18069.1 - 0.011 16.2 4.3 0.03 14.7 4.3 1.8 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 RepL PF05732.11 GAM18069.1 - 0.022 14.2 0.3 0.089 12.2 0.1 2.1 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) Imm42 PF15593.6 GAM18069.1 - 0.034 14.6 1.2 0.085 13.3 1.2 1.7 1 0 0 1 1 1 0 Immunity protein 42 ATP-synt_B PF00430.18 GAM18069.1 - 0.083 13.0 2.4 0.22 11.6 2.4 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) OSCP PF00213.18 GAM18069.1 - 0.15 12.2 3.4 0.11 12.6 0.5 2.2 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit DUF496 PF04363.12 GAM18069.1 - 0.27 11.3 2.7 0.35 10.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF496) RIH_assoc PF08454.11 GAM18069.1 - 0.38 10.6 3.0 1.2 9.0 1.2 2.7 2 0 0 2 2 2 0 RyR and IP3R Homology associated DUF2333 PF10095.9 GAM18069.1 - 0.38 9.7 4.4 1 8.3 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) BCDHK_Adom3 PF10436.9 GAM18069.1 - 1 9.2 5.1 1.8 8.4 0.2 2.7 3 1 0 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Exonuc_VII_L PF02601.15 GAM18069.1 - 3.6 7.1 7.4 8 5.9 6.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit GIDA_assoc PF13932.6 GAM18069.1 - 6 7.0 8.7 12 6.0 7.9 1.9 1 1 0 1 1 1 0 GidA associated domain DUF1394 PF07159.12 GAM18070.1 - 5.9e-124 413.2 0.4 6.7e-124 413.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) PNRC PF15365.6 GAM18071.1 - 5.8e-08 32.3 7.3 5.8e-08 32.3 7.3 2.7 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif KdpC PF02669.15 GAM18071.1 - 0.14 12.0 1.4 0.28 11.0 1.4 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain adh_short PF00106.25 GAM18072.1 - 5.3e-37 127.2 0.1 8.2e-37 126.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM18072.1 - 6.6e-23 81.5 0.2 1e-22 80.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM18072.1 - 7.7e-09 35.7 0.1 1.2e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM18072.1 - 0.0014 18.1 0.1 0.0021 17.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAM18072.1 - 0.0017 17.8 0.1 0.0035 16.8 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 GAM18072.1 - 0.0052 16.0 0.1 0.0066 15.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Snf7 PF03357.21 GAM18073.1 - 1.2e-34 119.4 8.2 1.6e-34 119.0 8.2 1.1 1 0 0 1 1 1 1 Snf7 LCD1 PF09798.9 GAM18073.1 - 0.02 13.5 6.2 0.022 13.3 6.2 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4366 PF14283.6 GAM18073.1 - 0.026 14.5 1.2 0.042 13.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF5082 PF16888.5 GAM18073.1 - 0.2 12.0 7.1 0.05 13.9 3.5 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) TMF_DNA_bd PF12329.8 GAM18073.1 - 0.45 10.6 13.2 0.056 13.4 4.4 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 GAM18073.1 - 0.6 9.4 5.8 6.6 6.0 6.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 GAM18073.1 - 1.3 9.7 7.2 14 6.4 0.3 3.0 3 0 0 3 3 3 0 SlyX ZapB PF06005.12 GAM18073.1 - 1.9 9.0 10.2 1.1 9.8 3.3 3.0 2 1 0 2 2 2 0 Cell division protein ZapB FKBP_N PF01346.18 GAM18073.1 - 3.2 8.8 8.4 0.42 11.6 2.2 2.2 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF4337 PF14235.6 GAM18073.1 - 4.6 7.3 7.1 0.26 11.4 1.4 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4337) bZIP_1 PF00170.21 GAM18074.1 - 1e-05 25.5 17.4 4.1e-05 23.6 17.4 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM18074.1 - 0.00035 20.6 12.8 0.00035 20.6 12.8 2.7 1 1 2 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAM18074.1 - 0.019 15.5 9.4 0.019 15.5 9.4 2.5 2 1 1 3 3 3 0 bZIP Maf transcription factor Propep_M14 PF02244.16 GAM18074.1 - 0.037 14.4 2.6 0.6 10.5 0.6 2.8 2 0 0 2 2 2 0 Carboxypeptidase activation peptide Rhomboid PF01694.22 GAM18074.1 - 0.062 13.3 1.2 0.11 12.5 1.2 1.3 1 0 0 1 1 1 0 Rhomboid family DMPK_coil PF08826.10 GAM18074.1 - 0.098 12.8 10.6 0.056 13.6 7.7 2.1 1 1 1 2 2 2 0 DMPK coiled coil domain like HPP PF04982.13 GAM18075.1 - 4.9e-41 139.7 8.9 8.1e-41 139.0 8.9 1.3 1 0 0 1 1 1 1 HPP family CBFD_NFYB_HMF PF00808.23 GAM18076.1 - 4.9e-18 65.2 0.6 7.5e-18 64.6 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM18076.1 - 2.8e-10 40.6 0.0 2.8e-10 40.6 0.0 2.5 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 Peptidase_M24 PF00557.24 GAM18077.1 - 1.9e-53 181.3 0.0 3.6e-53 180.4 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 GAM18077.1 - 2.4e-25 88.6 0.0 4.6e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 GAM18077.1 - 0.0071 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3793) UCH PF00443.29 GAM18078.1 - 5.7e-46 157.1 1.5 9.8e-46 156.3 1.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM18078.1 - 2.7e-11 43.6 2.3 2.7e-11 43.6 2.3 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DBD_Tnp_Hermes PF10683.9 GAM18080.1 - 0.16 11.7 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Ribosomal_S27e PF01667.17 GAM18081.1 - 6.4e-24 83.4 3.0 7.7e-24 83.2 3.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zinc_ribbon_6 PF14599.6 GAM18081.1 - 0.031 14.3 0.5 0.044 13.8 0.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon DUF3795 PF12675.7 GAM18081.1 - 0.054 13.9 1.4 0.11 12.9 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3795) zf-CSL PF05207.13 GAM18081.1 - 1.1 9.1 4.4 1.9 8.3 4.4 1.6 1 1 0 1 1 1 0 CSL zinc finger EF-hand_1 PF00036.32 GAM18082.1 - 5.1e-15 53.8 1.1 7.3e-06 25.2 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 GAM18082.1 - 2e-12 47.4 0.1 1.4e-09 38.3 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM18082.1 - 5.2e-11 41.6 0.2 0.0013 18.5 0.1 3.6 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 GAM18082.1 - 4.9e-10 39.1 1.9 9.2e-08 31.8 0.3 3.4 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 GAM18082.1 - 1.4e-05 25.3 0.0 0.0023 18.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 GAM18082.1 - 0.00015 22.6 0.1 0.00027 21.7 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 GAM18082.1 - 0.00069 19.0 1.3 0.14 11.7 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 GAM18082.1 - 0.011 15.7 0.2 0.027 14.4 0.1 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 GAM18082.1 - 0.016 15.1 0.1 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 EF hand PB1 PF00564.24 GAM18082.1 - 0.13 12.2 1.0 3.3 7.7 0.0 3.0 3 1 1 4 4 4 0 PB1 domain Robl_LC7 PF03259.17 GAM18083.1 - 1.4e-14 53.7 0.0 1.6e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 GAM18083.1 - 0.00069 19.5 0.0 0.00086 19.2 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 DUF1506 PF07405.11 GAM18083.1 - 0.0034 17.6 0.1 0.0038 17.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1506) LSM PF01423.22 GAM18084.1 - 7.1e-18 64.1 0.7 1.1e-17 63.5 0.7 1.3 1 0 0 1 1 1 1 LSM domain Pro_isomerase PF00160.21 GAM18085.1 - 1.2e-48 165.4 0.4 1.8e-48 164.8 0.4 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 GAM18085.1 - 3.4e-18 64.6 6.6 8.6e-06 25.4 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM18085.1 - 7.6e-18 63.1 3.0 7e-05 22.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM18085.1 - 3.3e-12 45.9 4.2 0.00018 21.1 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 GAM18085.1 - 8.6e-09 34.9 2.8 0.00014 21.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM18085.1 - 7.2e-08 32.4 0.8 0.013 15.6 0.0 3.4 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 GAM18085.1 - 1.3e-07 31.1 0.5 0.18 11.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM18085.1 - 3.7e-07 30.3 0.9 0.00061 20.0 0.1 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM18085.1 - 1.7e-05 25.1 1.5 0.51 11.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM18085.1 - 1.9e-05 25.1 0.2 0.15 12.6 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM18085.1 - 3.9e-05 24.2 1.5 0.073 13.7 0.0 2.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM18085.1 - 7.5e-05 23.2 0.1 0.35 11.8 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM18085.1 - 0.00059 20.0 0.2 3.7 8.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM18085.1 - 0.00073 19.6 0.0 0.0038 17.4 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM18085.1 - 0.0011 18.7 0.6 2.4 8.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.7 GAM18085.1 - 0.0085 16.2 0.3 0.018 15.1 0.3 1.6 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) MIT PF04212.18 GAM18085.1 - 0.012 15.7 3.3 0.3 11.2 0.5 3.1 2 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain Glyco_trans_1_2 PF13524.6 GAM18085.1 - 0.029 14.8 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 ANAPC3 PF12895.7 GAM18085.1 - 0.044 14.0 3.7 0.062 13.5 1.7 2.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 GAM18085.1 - 0.058 13.4 1.5 0.1 12.7 1.5 1.5 1 1 0 1 1 1 0 Putative TPR-like repeat Ras PF00071.22 GAM18086.1 - 1.1e-30 106.4 0.0 2.1e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM18086.1 - 3.5e-20 72.4 0.0 9.2e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM18086.1 - 1.2e-14 54.1 0.0 2.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_6 PF13516.6 GAM18086.1 - 0.0014 18.5 33.8 0.012 15.6 0.4 7.1 8 0 0 8 8 8 3 Leucine Rich repeat MMR_HSR1 PF01926.23 GAM18086.1 - 0.0053 16.8 0.0 0.0053 16.8 0.0 2.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase DUF3439 PF11921.8 GAM18086.1 - 2.9 7.9 6.5 6.6 6.7 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LRR_8 PF13855.6 GAM18086.1 - 4 7.3 34.7 0.096 12.5 4.0 5.0 2 1 2 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 GAM18086.1 - 5.5 7.9 19.7 27 5.9 0.5 7.0 5 2 0 5 5 5 0 Leucine Rich Repeat zf-AN1 PF01428.16 GAM18087.1 - 7.2e-21 74.1 36.0 2.6e-10 40.3 14.6 2.8 2 0 0 2 2 2 2 AN1-like Zinc finger UBX PF00789.20 GAM18087.1 - 5.3e-09 36.2 0.1 1.6e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 UBX domain Coronavirus_5 PF05528.11 GAM18087.1 - 0.045 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Coronavirus gene 5 protein PAD_porph PF04371.15 GAM18087.1 - 0.054 12.8 0.1 0.077 12.3 0.1 1.1 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase Pkinase_Tyr PF07714.17 GAM18088.1 - 3.1e-60 203.6 0.0 5.1e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM18088.1 - 9.5e-57 192.3 0.2 2.7e-56 190.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Filamin PF00630.19 GAM18088.1 - 7.5e-05 23.5 0.2 0.00023 21.9 0.0 2.0 2 0 0 2 2 2 1 Filamin/ABP280 repeat Pkinase_fungal PF17667.1 GAM18088.1 - 0.00025 19.9 3.1 0.02 13.7 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase Ubiquitin_2 PF14560.6 GAM18088.1 - 0.0048 17.3 0.0 0.024 15.1 0.0 2.3 1 0 0 1 1 1 1 Ubiquitin-like domain Haspin_kinase PF12330.8 GAM18088.1 - 0.0069 15.4 0.2 0.0069 15.4 0.2 3.0 2 1 1 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 GAM18088.1 - 0.015 14.6 1.2 0.018 14.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 GAM18088.1 - 0.23 11.3 0.1 0.52 10.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Presenilin PF01080.17 GAM18088.1 - 0.46 9.2 4.0 1.3 7.7 4.0 1.7 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 GAM18088.1 - 3 7.4 26.8 0.024 14.2 15.2 2.5 2 0 0 2 2 2 0 Spt20 family CRF-BP PF05428.11 GAM18089.1 - 0.11 11.2 0.2 0.11 11.2 0.2 1.0 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Glyco_hydro_47 PF01532.20 GAM18090.1 - 1.1e-83 281.7 5.6 1.4e-83 281.3 5.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 GAM18090.1 - 0.00067 19.0 0.2 0.34 10.1 0.0 3.0 3 0 0 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 GAM18090.1 - 0.0092 15.5 6.8 1.2 8.5 0.2 3.3 1 1 2 3 3 3 2 Glycosyl hydrolase family 76 UPF0093 PF03653.13 GAM18090.1 - 0.17 12.1 0.3 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) Cofilin_ADF PF00241.20 GAM18091.1 - 2.7e-27 94.9 0.4 3.1e-27 94.8 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pkinase PF00069.25 GAM18093.1 - 2.5e-66 223.8 0.0 2.5e-66 223.8 0.0 3.1 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18093.1 - 9.5e-33 113.6 0.0 9.5e-33 113.6 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase DDHD PF02862.17 GAM18093.1 - 0.00088 19.5 21.0 0.007 16.5 8.8 2.4 2 0 0 2 2 2 2 DDHD domain Exonuc_VII_L PF02601.15 GAM18093.1 - 0.13 11.8 39.6 0.055 13.0 20.2 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit UPF0565 PF10561.9 GAM18093.1 - 0.19 10.9 16.1 0.73 9.0 6.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 DUF4471 PF14740.6 GAM18093.1 - 0.27 10.4 21.0 0.056 12.7 8.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Otopetrin PF03189.13 GAM18093.1 - 1.4 7.7 16.1 0.3 9.9 7.2 2.2 2 0 0 2 2 2 0 Otopetrin Ndc1_Nup PF09531.10 GAM18093.1 - 2.9 6.4 24.0 0.21 10.2 11.5 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Piezo_RRas_bdg PF12166.8 GAM18094.1 - 4.1e-93 313.0 2.3 4.1e-93 313.0 2.3 2.0 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain DUF3484 PF11983.8 GAM18094.1 - 0.0068 17.5 0.6 0.0068 17.5 0.6 2.3 2 0 0 2 2 2 1 Membrane-attachment and polymerisation-promoting switch DUF4201 PF13870.6 GAM18094.1 - 0.17 11.6 2.8 0.35 10.6 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) OAD_gamma PF04277.13 GAM18094.1 - 9.1 7.0 9.3 0.58 10.8 0.2 3.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain FNIP PF05725.12 GAM18095.1 - 1.1e-56 188.8 8.7 1.4e-11 44.3 1.5 7.8 5 2 1 8 8 8 7 FNIP Repeat SPX PF03105.19 GAM18096.1 - 3.7e-20 73.2 13.1 2.8e-09 37.4 0.4 3.2 1 1 2 3 3 3 3 SPX domain EF-hand_1 PF00036.32 GAM18096.1 - 0.0013 18.2 0.1 0.46 10.1 0.0 3.1 4 0 0 4 4 4 2 EF hand Nsp1_C PF05064.13 GAM18096.1 - 0.03 14.1 0.5 0.1 12.4 0.5 1.9 1 1 0 1 1 1 0 Nsp1-like C-terminal region ACP_PD PF04336.12 GAM18096.1 - 0.049 14.1 0.4 0.11 12.9 0.2 1.7 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase TFIIA_gamma_N PF02268.16 GAM18096.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain DUF2207 PF09972.9 GAM18097.1 - 0.00012 21.0 0.6 0.00016 20.6 0.6 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SPX PF03105.19 GAM18097.1 - 0.0045 17.0 3.4 0.005 16.8 3.4 1.1 1 0 0 1 1 1 1 SPX domain Dsh_C PF12316.8 GAM18097.1 - 0.0074 16.7 16.9 0.011 16.1 16.9 1.2 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal DUF812 PF05667.11 GAM18097.1 - 0.043 12.7 1.2 0.047 12.6 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SOG2 PF10428.9 GAM18097.1 - 0.058 12.6 25.3 0.07 12.3 25.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 GAM18097.1 - 0.39 9.2 10.4 0.48 8.9 10.4 1.3 1 0 0 1 1 1 0 Macoilin family RIFIN PF02009.16 GAM18097.1 - 0.65 9.8 10.9 0.42 10.5 8.7 1.8 1 1 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 GAM18097.1 - 0.68 9.3 9.5 0.84 9.0 9.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Smg8_Smg9 PF10220.9 GAM18097.1 - 1.4 7.1 7.4 2.2 6.5 7.4 1.2 1 0 0 1 1 1 0 Smg8_Smg9 Mitofilin PF09731.9 GAM18097.1 - 1.9 7.2 7.5 2.5 6.8 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MecA PF05389.12 GAM18097.1 - 2 8.0 8.1 21 4.7 4.0 2.7 1 1 1 2 2 2 0 Negative regulator of genetic competence (MecA) Ashwin PF15323.6 GAM18097.1 - 6.1 6.8 25.6 0.8 9.7 21.4 1.6 2 0 0 2 2 2 0 Developmental protein RPN7 PF10602.9 GAM18098.1 - 6.6e-55 185.5 0.9 1.1e-54 184.8 0.9 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GAM18098.1 - 8.8e-18 64.8 0.0 4.6e-17 62.4 0.0 2.3 2 0 0 2 2 2 1 PCI domain SDH_alpha PF03313.15 GAM18099.1 - 0.019 14.6 1.7 0.021 14.5 1.7 1.1 1 0 0 1 1 1 0 Serine dehydratase alpha chain Coiled PF05710.12 GAM18099.1 - 0.035 14.9 19.7 0.15 12.9 19.7 1.8 1 1 0 1 1 1 0 Coiled coil DUF1084 PF06454.11 GAM18100.1 - 2.7e-15 56.5 22.6 2e-14 53.6 22.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Ninjurin PF04923.12 GAM18100.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.5 2 1 1 3 3 3 0 Ninjurin TIG PF01833.24 GAM18102.1 - 2.2e-10 40.5 44.5 8.1e-07 29.0 3.6 7.0 5 1 2 7 7 7 4 IPT/TIG domain PHD PF00628.29 GAM18103.1 - 2.3e-06 27.4 18.2 0.00022 21.0 3.6 3.5 3 0 0 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.6 GAM18103.1 - 0.0001 22.5 22.5 0.0026 18.0 3.9 3.3 2 1 1 3 3 3 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GAM18103.1 - 0.0068 16.6 21.7 0.032 14.4 5.0 3.1 2 1 1 3 3 3 2 PHD-zinc-finger like domain FANCL_C PF11793.8 GAM18103.1 - 3.8 7.8 15.4 21 5.4 3.5 2.5 1 1 1 2 2 2 0 FANCL C-terminal domain Glyco_transf_49 PF13896.6 GAM18104.1 - 3e-48 164.9 3.2 2.8e-38 132.1 0.8 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAM18104.1 - 0.00077 19.3 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 GAM18104.1 - 0.017 15.6 0.4 0.039 14.5 0.4 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 PARP PF00644.20 GAM18105.1 - 1.2e-28 100.0 1.0 7.1e-28 97.5 1.0 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 GAM18105.1 - 8e-11 42.2 0.7 1.8e-10 41.1 0.7 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 GAM18105.1 - 1.2e-05 25.2 0.3 2.6e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 WGR domain FAM92 PF06730.11 GAM18105.1 - 0.0012 18.4 0.0 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 FAM92 protein Nuc_recep-AF1 PF11825.8 GAM18105.1 - 0.0017 18.4 1.3 0.0048 16.9 0.4 2.3 2 0 0 2 2 2 1 Nuclear/hormone receptor activator site AF-1 DDE_3 PF13358.6 GAM18105.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Sec23_helical PF04815.15 GAM18106.1 - 1e-16 60.6 0.1 6.6e-16 58.0 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_trunk PF04811.15 GAM18106.1 - 1.4e-15 57.6 0.0 3.5e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GAM18106.1 - 4.8e-06 27.2 0.0 1.2e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAM18106.1 - 0.057 13.5 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger FNIP PF05725.12 GAM18107.1 - 5.2e-45 151.4 26.3 6.8e-13 48.6 2.6 8.7 7 3 2 9 9 9 7 FNIP Repeat FNIP PF05725.12 GAM18108.1 - 1.5e-27 95.4 24.9 6e-13 48.7 0.1 7.7 9 0 0 9 9 9 5 FNIP Repeat LRR_8 PF13855.6 GAM18108.1 - 2.3 8.1 14.4 0.14 12.0 0.8 4.4 4 1 1 5 5 5 0 Leucine rich repeat FNIP PF05725.12 GAM18109.1 - 1.7e-12 47.3 0.1 8e-07 29.1 0.0 3.1 2 1 1 3 3 3 2 FNIP Repeat FNIP PF05725.12 GAM18110.1 - 1.1e-27 95.9 16.3 2.6e-13 49.9 0.1 4.1 4 2 2 6 6 6 3 FNIP Repeat Lipoprotein_15 PF03640.15 GAM18111.1 - 2.2e-31 107.1 0.7 9.9e-12 44.2 0.1 3.7 4 0 0 4 4 4 3 Secreted repeat of unknown function WW_1 PF18507.1 GAM18111.1 - 0.17 11.6 6.8 3.8 7.3 0.0 4.0 4 0 0 4 4 4 0 WW domain RXT2_N PF08595.11 GAM18114.1 - 0.23 11.5 5.6 0.055 13.5 1.4 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal PTPRCAP PF15713.5 GAM18114.1 - 0.38 11.0 5.3 0.22 11.8 2.4 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PBP1_TM PF14812.6 GAM18114.1 - 2.9 8.3 11.4 1.7 9.1 5.0 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 GAM18114.1 - 8.9 4.3 8.3 15 3.5 8.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi FNIP PF05725.12 GAM18116.1 - 4.5e-99 324.4 36.8 1e-12 48.0 0.1 13.1 11 3 4 15 15 15 12 FNIP Repeat LSM PF01423.22 GAM18118.1 - 1.2e-18 66.5 0.1 1.5e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM18118.1 - 0.071 13.3 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain mRNA_decap_C PF16741.5 GAM18118.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus Methyltransf_4 PF02390.17 GAM18119.1 - 9.3e-27 93.6 0.0 2.2e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PPR_2 PF13041.6 GAM18119.1 - 9e-16 57.8 0.1 2.9e-07 30.6 0.0 3.9 2 1 1 3 3 3 3 PPR repeat family PPR PF01535.20 GAM18119.1 - 5.1e-10 38.9 0.4 0.00037 20.5 0.0 5.1 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 GAM18119.1 - 3.4e-08 33.4 0.1 0.00029 20.9 0.0 3.9 2 1 1 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAM18119.1 - 4.9e-08 32.5 0.2 0.0006 19.5 0.0 3.5 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 GAM18119.1 - 6e-08 32.3 0.0 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP MTS PF05175.14 GAM18119.1 - 0.064 12.8 0.6 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain Ndc1_Nup PF09531.10 GAM18119.1 - 4.7 5.8 13.5 8.2 5.0 13.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SWI-SNF_Ssr4 PF08549.10 GAM18119.1 - 7.7 5.0 23.3 13 4.3 23.3 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) FSA_C PF10479.9 GAM18119.1 - 9.4 4.2 20.5 14 3.7 20.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Nucleoporin_FG PF13634.6 GAM18120.1 - 1.2e-14 54.9 188.1 0.001 19.8 41.2 6.7 1 1 5 6 6 6 6 Nucleoporin FG repeat region SUIM_assoc PF16619.5 GAM18120.1 - 0.018 15.1 2.6 0.13 12.4 2.6 2.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 BRAP2 PF07576.12 GAM18121.1 - 2.2e-32 111.2 0.1 5.2e-32 110.0 0.1 1.7 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 GAM18121.1 - 3.6e-19 68.9 6.9 8.2e-19 67.7 6.9 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 GAM18121.1 - 1.4e-08 34.9 9.8 1.4e-08 34.9 9.8 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM18121.1 - 3e-07 30.1 9.2 9.3e-07 28.6 9.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM18121.1 - 2.9e-05 24.3 7.2 2.9e-05 24.3 7.2 2.5 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAM18121.1 - 0.00017 21.6 8.9 0.00056 19.9 8.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAM18121.1 - 0.00023 21.0 8.0 0.00023 21.0 8.0 2.3 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM18121.1 - 0.0003 20.7 7.5 0.0003 20.7 7.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAM18121.1 - 0.00085 19.0 6.3 0.00085 19.0 6.3 2.4 2 0 0 2 2 1 1 RING-like zinc finger RRM_1 PF00076.22 GAM18121.1 - 0.0027 17.5 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 GAM18121.1 - 0.0028 17.5 6.8 0.0028 17.5 6.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 GAM18121.1 - 0.0036 17.0 3.1 0.0036 17.0 3.1 2.2 2 1 1 3 3 2 1 RING/Ubox like zinc-binding domain zf-UBP_var PF17807.1 GAM18121.1 - 0.0054 16.5 0.9 0.015 15.0 0.9 1.7 1 0 0 1 1 1 1 Variant UBP zinc finger ArfGap PF01412.18 GAM18121.1 - 0.012 15.7 4.2 0.012 15.7 4.2 2.4 1 1 0 2 2 2 0 Putative GTPase activating protein for Arf zf-ANAPC11 PF12861.7 GAM18121.1 - 0.014 15.4 6.8 0.014 15.4 6.8 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sec20 PF03908.13 GAM18121.1 - 0.12 12.3 0.7 0.26 11.2 0.7 1.6 1 0 0 1 1 1 0 Sec20 PHF5 PF03660.14 GAM18121.1 - 0.15 12.3 11.2 0.18 12.0 9.4 2.1 2 0 0 2 2 2 0 PHF5-like protein ApoO PF09769.9 GAM18121.1 - 0.17 11.8 0.5 0.42 10.6 0.5 1.6 1 0 0 1 1 1 0 Apolipoprotein O PHM7_cyt PF14703.6 GAM18121.1 - 0.19 11.9 6.8 0.27 11.4 5.3 1.9 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Exonuc_VII_L PF02601.15 GAM18121.1 - 0.57 9.7 5.3 0.91 9.0 5.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.8 GAM18121.1 - 3 7.2 15.2 5.2 6.4 15.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4337 PF14235.6 GAM18121.1 - 5.1 7.2 5.9 9 6.4 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TMF_TATA_bd PF12325.8 GAM18121.1 - 7.4 6.8 14.9 29 4.9 14.9 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF974 PF06159.13 GAM18122.1 - 3e-51 174.6 0.0 6.1e-51 173.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 GAM18122.1 - 0.026 14.0 0.6 0.41 10.0 0.0 2.7 2 1 1 3 3 3 0 TRAPP trafficking subunit Trs65 DHO_dh PF01180.21 GAM18123.1 - 7.2e-34 117.3 0.0 3.3e-33 115.2 0.0 2.1 3 0 0 3 3 3 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 GAM18123.1 - 7.2e-33 112.7 0.7 7.2e-33 112.7 0.7 2.6 2 2 0 2 2 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 GAM18123.1 - 5.1e-23 81.0 13.5 5.1e-23 81.0 13.5 3.7 4 0 0 4 4 4 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 GAM18123.1 - 3.8e-11 42.8 0.0 1e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Dus PF01207.17 GAM18123.1 - 7.6e-07 28.5 0.0 1.9e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Fer4_10 PF13237.6 GAM18123.1 - 4.4e-06 26.7 27.1 1.5e-05 25.0 8.1 3.6 3 1 0 3 3 3 2 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 GAM18123.1 - 2e-05 24.0 0.0 0.043 13.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM18123.1 - 7.3e-05 22.9 0.0 0.00024 21.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM18123.1 - 8.6e-05 23.0 0.1 0.4 11.3 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 GAM18123.1 - 0.00013 22.5 10.3 0.00013 22.5 10.3 3.8 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAM18123.1 - 0.00015 21.7 1.7 0.00015 21.7 1.7 5.1 6 0 0 6 6 4 3 4Fe-4S binding domain Fer4_2 PF12797.7 GAM18123.1 - 0.0017 18.4 40.7 0.0068 16.4 2.4 5.4 6 0 0 6 6 6 3 4Fe-4S binding domain Fer4 PF00037.27 GAM18123.1 - 0.002 17.9 14.9 0.0034 17.1 4.2 4.9 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_9 PF13187.6 GAM18123.1 - 0.0022 18.1 11.7 0.0022 18.1 11.7 3.4 4 0 0 4 4 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 GAM18123.1 - 0.14 12.8 24.2 0.14 12.7 0.9 4.3 4 0 0 4 4 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 GAM18123.1 - 0.94 10.3 10.7 3.2 8.5 0.5 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain UPF0113_N PF17833.1 GAM18124.1 - 0.032 14.8 0.4 0.1 13.2 0.4 1.9 1 0 0 1 1 1 0 UPF0113 Pre-PUA domain NopRA1 PF16201.5 GAM18124.1 - 0.067 12.8 0.8 0.59 9.7 0.2 3.1 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 Histone PF00125.24 GAM18127.1 - 1.4e-20 74.0 5.4 1.7e-20 73.7 5.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAM18127.1 - 0.0087 16.3 0.4 0.0087 16.3 0.4 1.9 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 GAM18127.1 - 0.024 15.0 0.1 0.048 14.1 0.1 1.4 1 0 0 1 1 1 0 CENP-S protein CNP_C_terminal PF17839.1 GAM18127.1 - 0.052 14.3 0.4 0.089 13.5 0.4 1.3 1 0 0 1 1 1 0 C-terminal domain of cyclic nucleotide phosphodiesterase MATalpha_HMGbox PF04769.12 GAM18127.1 - 0.076 12.3 1.5 0.11 11.8 1.3 1.3 1 1 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Histone PF00125.24 GAM18128.1 - 3.1e-19 69.6 8.7 4.1e-19 69.2 8.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAM18128.1 - 0.00012 22.3 0.3 0.00033 20.9 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GAM18128.1 - 0.016 15.7 0.1 0.031 14.8 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF908 PF06012.12 GAM18128.1 - 0.27 10.6 3.0 0.32 10.4 3.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) IHABP4_N PF16174.5 GAM18128.1 - 1.1 9.9 8.7 1.6 9.3 8.7 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Methyltransf_2 PF00891.18 GAM18130.1 - 4.8e-38 130.6 0.0 7.1e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 GAM18130.1 - 5.3e-08 32.7 0.1 3.7e-07 30.0 0.1 2.1 2 0 0 2 2 2 1 Dimerisation domain Rrf2 PF02082.20 GAM18130.1 - 0.0026 18.1 0.0 0.005 17.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_AraC PF00165.23 GAM18130.1 - 0.018 15.1 0.0 0.066 13.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_3 PF01381.22 GAM18130.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_20 PF12840.7 GAM18130.1 - 0.1 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase PF00069.25 GAM18131.1 - 3.5e-60 203.6 0.0 6.3e-60 202.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18131.1 - 6.1e-43 147.0 0.0 1.6e-42 145.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM18131.1 - 0.00017 21.0 0.0 0.00047 19.6 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAM18131.1 - 0.0016 18.4 0.0 0.067 13.1 0.0 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM18131.1 - 0.0049 15.7 0.0 0.014 14.2 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase CENP-B_dimeris PF09026.10 GAM18131.1 - 0.95 9.9 14.6 4.2 7.8 6.8 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pkinase PF00069.25 GAM18132.1 - 1e-68 231.6 0.0 1e-68 231.6 0.0 4.2 5 1 1 6 6 6 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18132.1 - 2.2e-48 164.8 3.3 2.4e-47 161.4 0.0 3.0 3 0 0 3 3 3 1 Protein tyrosine kinase DUF5133 PF17196.4 GAM18132.1 - 0.085 13.1 1.3 1.7 8.9 0.1 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) APH PF01636.23 GAM18132.1 - 0.38 10.6 0.0 0.38 10.6 0.0 4.1 4 2 0 4 4 4 0 Phosphotransferase enzyme family DDE_Tnp_1_7 PF13843.6 GAM18133.1 - 3.1e-31 109.0 0.0 6.5e-31 107.9 0.0 1.5 1 1 0 1 1 1 1 Transposase IS4 VWA PF00092.28 GAM18134.1 - 2.4e-12 47.4 0.0 1e-10 42.1 0.0 3.5 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM18134.1 - 6.1e-10 39.7 0.0 4.4e-09 36.9 0.0 2.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 GAM18134.1 - 0.0011 18.8 0.0 0.0045 16.8 0.0 2.1 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A VWA_CoxE PF05762.14 GAM18134.1 - 0.012 15.1 1.9 2 7.7 0.0 3.6 3 1 0 3 3 3 0 VWA domain containing CoxE-like protein F-box-like PF12937.7 GAM18134.1 - 0.047 13.6 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 GAM18134.1 - 0.12 12.3 0.3 0.55 10.2 0.3 2.2 1 0 0 1 1 1 0 F-box domain FNIP PF05725.12 GAM18135.1 - 2e-57 191.1 22.5 4.9e-12 45.8 0.0 10.6 6 3 8 14 14 14 12 FNIP Repeat LRR_5 PF13306.6 GAM18135.1 - 0.00037 20.5 0.0 0.0046 16.9 0.0 2.7 3 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) AAA PF00004.29 GAM18136.1 - 6.5e-38 130.1 0.0 1.8e-37 128.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM18136.1 - 3.3e-12 46.0 0.0 6.9e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 GAM18136.1 - 5.3e-10 39.1 2.1 1.3e-09 37.9 0.1 2.7 4 0 0 4 4 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 GAM18136.1 - 1.7e-05 24.6 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAM18136.1 - 9.9e-05 22.4 0.0 0.00085 19.3 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM18136.1 - 0.00075 19.8 0.1 0.023 15.0 0.0 2.9 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 GAM18136.1 - 0.0011 18.2 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 GAM18136.1 - 0.0021 18.5 0.2 0.03 14.7 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 GAM18136.1 - 0.0039 17.3 0.2 0.019 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 GAM18136.1 - 0.013 16.1 0.1 0.05 14.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 GAM18136.1 - 0.025 14.0 0.1 0.069 12.5 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAM18136.1 - 0.054 13.9 0.0 0.22 11.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 GAM18136.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 GAM18136.1 - 0.1 12.1 0.0 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAM18136.1 - 0.11 12.2 1.4 0.55 9.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain GUB_WAK_bind PF13947.6 GAM18136.1 - 5 7.9 5.7 1.7 9.4 1.3 2.4 2 0 0 2 2 2 0 Wall-associated receptor kinase galacturonan-binding VWA_2 PF13519.6 GAM18137.1 - 5.3e-08 33.5 0.6 8.4e-06 26.4 0.0 3.4 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 GAM18137.1 - 5.1e-05 22.8 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein VWA PF00092.28 GAM18137.1 - 0.0018 18.5 6.1 0.015 15.5 2.4 2.9 2 1 0 2 2 2 1 von Willebrand factor type A domain Sec23_BS PF08033.12 GAM18137.1 - 0.0034 18.1 1.9 0.023 15.4 1.0 2.7 2 1 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAM18137.1 - 0.035 14.2 0.6 0.12 12.4 0.6 1.9 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger ERG4_ERG24 PF01222.17 GAM18138.1 - 1.4e-120 403.0 12.9 1.7e-120 402.7 12.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 GAM18138.1 - 7.6e-05 22.3 1.6 0.00013 21.5 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Ras PF00071.22 GAM18139.1 - 3.3e-58 195.9 0.3 4.1e-58 195.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM18139.1 - 3.4e-36 124.1 0.1 4.8e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM18139.1 - 5.8e-14 51.9 0.3 6.6e-14 51.7 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAM18139.1 - 6.4e-06 25.7 0.1 2.9e-05 23.6 0.1 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAM18139.1 - 1.2e-05 25.0 0.1 8.6e-05 22.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAM18139.1 - 0.00019 20.9 0.2 0.00025 20.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM18139.1 - 0.00019 21.5 0.0 0.0003 20.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM18139.1 - 0.00072 19.5 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAM18139.1 - 0.017 14.7 0.1 0.23 11.0 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B F5_F8_type_C PF00754.25 GAM18140.1 - 1.2e-21 77.1 0.8 1.4e-21 76.9 0.8 1.0 1 0 0 1 1 1 1 F5/8 type C domain MMR_HSR1 PF01926.23 GAM18141.1 - 2.3e-15 56.7 0.0 1.9e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM18141.1 - 3.1e-05 23.6 0.0 6.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAM18141.1 - 7.4e-05 22.7 0.1 0.0043 17.0 0.0 2.6 1 1 0 2 2 2 1 RsgA GTPase Parvo_NS1 PF01057.17 GAM18141.1 - 0.00011 21.4 0.0 0.00021 20.5 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IIGP PF05049.13 GAM18141.1 - 0.0027 16.9 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.27 GAM18141.1 - 0.0089 15.6 0.1 1.3 8.5 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GAM18141.1 - 0.051 13.6 2.8 3 7.9 0.1 3.7 3 1 1 4 4 4 0 Dynamin family AAA_29 PF13555.6 GAM18141.1 - 0.078 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM18141.1 - 0.099 13.0 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 GAM18141.1 - 0.11 11.9 0.0 4.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MCM PF00493.23 GAM18141.1 - 0.13 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain HAND PF09110.11 GAM18141.1 - 0.26 12.0 4.4 2.6 8.8 0.5 2.4 2 0 0 2 2 2 0 HAND Pex14_N PF04695.13 GAM18141.1 - 0.7 10.5 13.2 0.49 11.0 1.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PEPCK_ATP PF01293.20 GAM18142.1 - 3.8e-222 738.0 0.0 4.5e-222 737.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 GAM18142.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rap_GAP PF02145.15 GAM18145.1 - 4.4e-62 208.9 0.1 9.5e-62 207.9 0.1 1.6 1 0 0 1 1 1 1 Rap/ran-GAP PH PF00169.29 GAM18145.1 - 2.8e-20 72.8 14.1 1.6e-06 28.5 3.0 3.7 1 1 2 3 3 3 3 PH domain PH_11 PF15413.6 GAM18145.1 - 3.7e-07 30.5 15.5 0.0031 17.9 0.4 4.4 3 1 0 3 3 3 2 Pleckstrin homology domain PH_10 PF15411.6 GAM18145.1 - 0.0041 17.4 0.3 0.011 16.0 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain MatE PF01554.18 GAM18146.1 - 5.3e-63 211.5 35.2 1.4e-33 115.9 9.8 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAM18146.1 - 5.8e-07 29.7 15.5 2.8e-06 27.4 4.4 4.0 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain EGF_2 PF07974.13 GAM18148.1 - 0.013 15.9 9.3 0.027 14.8 9.3 1.5 1 0 0 1 1 1 0 EGF-like domain EB PF01683.18 GAM18148.1 - 0.14 12.4 4.5 0.32 11.3 4.5 1.6 1 1 0 1 1 1 0 EB module I-EGF_1 PF18372.1 GAM18148.1 - 0.17 12.0 5.0 0.46 10.6 5.0 1.6 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EGF_Tenascin PF18720.1 GAM18148.1 - 0.3 11.2 3.1 0.75 9.9 3.1 1.7 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 GAM18148.1 - 3 8.6 9.4 9.1 7.1 9.4 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF UCH PF00443.29 GAM18149.1 - 4.7e-55 186.9 0.0 2.1e-54 184.8 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM18149.1 - 1.8e-14 54.1 2.4 1.8e-14 54.1 2.4 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAM18149.1 - 5.4e-10 39.4 11.6 5.4e-10 39.4 11.6 3.1 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 GAM18149.1 - 0.0044 16.7 1.0 0.01 15.6 1.0 1.6 1 0 0 1 1 1 1 Variant UBP zinc finger HlyIII PF03006.20 GAM18151.1 - 7.7e-42 143.5 24.3 9.8e-42 143.2 24.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related FSA_C PF10479.9 GAM18151.1 - 0.023 12.9 1.8 0.031 12.4 1.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF2614 PF11023.8 GAM18151.1 - 5 7.3 7.1 8.9 6.4 0.5 2.6 2 1 0 2 2 2 0 Zinc-ribbon containing domain FNIP PF05725.12 GAM18152.1 - 0.017 15.3 34.0 0.028 14.6 0.2 7.5 7 1 1 8 8 8 0 FNIP Repeat PB1 PF00564.24 GAM18153.1 - 2.2e-09 37.1 0.0 4.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 PB1 domain DUF3870 PF12986.7 GAM18154.1 - 0.062 13.5 0.3 0.2 11.9 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) HSP70 PF00012.20 GAM18155.1 - 4.3e-256 850.9 11.2 4.9e-256 850.7 11.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM18155.1 - 5.4e-16 58.3 0.1 4.8e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GAM18155.1 - 1.2e-05 25.6 3.7 0.021 15.3 0.0 3.7 3 1 0 3 3 3 1 Cell division protein FtsA DUF4795 PF16043.5 GAM18155.1 - 0.0033 17.0 1.5 0.0033 17.0 1.5 3.0 3 1 1 4 4 4 1 Domain of unknown function (DUF4795) DDE_Tnp_IS1 PF03400.13 GAM18155.1 - 0.025 14.9 0.0 0.58 10.5 0.0 2.5 2 0 0 2 2 2 0 IS1 transposase Pox_D5 PF03288.16 GAM18155.1 - 0.032 14.7 0.2 0.093 13.2 0.2 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like DDR PF08841.10 GAM18155.1 - 0.037 13.0 0.1 0.32 10.0 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF592 PF04574.13 GAM18155.1 - 0.045 13.5 0.6 0.045 13.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF592) Dcc1 PF09724.9 GAM18155.1 - 0.053 12.8 0.1 0.053 12.8 0.1 1.7 2 0 0 2 2 2 0 Sister chromatid cohesion protein Dcc1 FGGY_C PF02782.16 GAM18155.1 - 0.083 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.11 GAM18155.1 - 0.14 11.4 9.6 0.014 14.7 4.0 1.9 2 0 0 2 2 2 0 Radial spoke protein 3 Pex19 PF04614.12 GAM18155.1 - 1.1 8.9 9.6 0.27 11.0 3.0 2.3 2 0 0 2 2 2 0 Pex19 protein family LZ3wCH PF18517.1 GAM18155.1 - 7.5 6.7 8.0 0.82 9.8 0.2 3.2 3 0 0 3 3 3 0 Leucine zipper with capping helix domain WD-3 PF09765.9 GAM18156.1 - 6.5e-53 179.9 0.1 2.1e-51 174.9 0.1 2.5 1 1 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 GAM18156.1 - 6.3e-27 93.6 3.6 9.8e-27 92.9 3.6 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 GAM18156.1 - 0.00011 22.5 6.4 0.0002 21.6 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 GAM18156.1 - 0.00089 19.5 0.9 0.0016 18.6 0.9 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 GAM18156.1 - 0.022 14.9 0.3 0.039 14.1 0.3 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 GAM18156.1 - 0.088 13.1 1.6 0.2 12.0 1.6 1.6 1 0 0 1 1 1 0 RING-like domain Prok-E2_B PF14461.6 GAM18156.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B zf-rbx1 PF12678.7 GAM18156.1 - 0.19 12.1 7.1 0.53 10.6 7.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain RINGv PF12906.7 GAM18156.1 - 0.54 10.4 4.1 1.1 9.5 4.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 GAM18156.1 - 2.2 8.4 5.1 8 6.6 5.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CDC27 PF09507.10 GAM18157.1 - 0.44 9.9 13.3 0.59 9.5 13.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hamartin PF04388.12 GAM18157.1 - 0.5 9.0 10.6 0.64 8.6 10.6 1.1 1 0 0 1 1 1 0 Hamartin protein WBP-1 PF11669.8 GAM18158.1 - 0.018 15.7 1.0 0.018 15.7 1.0 1.6 2 0 0 2 2 2 0 WW domain-binding protein 1 MLANA PF14991.6 GAM18158.1 - 0.032 14.5 0.1 0.045 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein melan-A EphA2_TM PF14575.6 GAM18158.1 - 0.076 13.9 0.2 0.17 12.8 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 GAM18158.1 - 0.88 10.4 3.7 0.33 11.7 0.7 1.9 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal NACHT PF05729.12 GAM18159.1 - 0.037 13.9 0.0 0.067 13.1 0.0 1.6 1 1 0 1 1 1 0 NACHT domain ATPase PF06745.13 GAM18159.1 - 0.044 13.1 0.0 3.3 7.0 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_5 PF07728.14 GAM18159.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM18159.1 - 0.21 12.0 0.0 0.32 11.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DUF3336 PF11815.8 GAM18160.1 - 1e-37 129.0 3.6 7.1e-37 126.2 1.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAM18160.1 - 3.7e-23 82.8 0.0 7.5e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF4770 PF15994.5 GAM18160.1 - 0.0026 18.0 7.1 0.0049 17.1 7.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) DUF4175 PF13779.6 GAM18160.1 - 0.0034 15.4 6.8 0.0044 15.0 6.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) BSMAP PF12280.8 GAM18160.1 - 0.017 15.4 6.9 0.03 14.5 6.9 1.4 1 0 0 1 1 1 0 Brain specific membrane anchored protein DDHD PF02862.17 GAM18160.1 - 0.025 14.7 5.6 0.044 13.9 5.6 1.3 1 0 0 1 1 1 0 DDHD domain Pex14_N PF04695.13 GAM18160.1 - 0.05 14.3 14.4 0.11 13.1 14.4 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.22 GAM18160.1 - 0.091 12.0 4.9 0.15 11.2 4.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter MMR1 PF08505.10 GAM18160.1 - 0.13 12.6 17.4 0.21 11.8 17.4 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Activator_LAG-3 PF11498.8 GAM18160.1 - 0.21 10.5 26.3 0.34 9.8 26.3 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Velvet PF11754.8 GAM18160.1 - 0.22 11.4 9.7 0.35 10.8 9.7 1.2 1 0 0 1 1 1 0 Velvet factor FAM199X PF15814.5 GAM18160.1 - 0.28 10.2 12.2 0.49 9.4 12.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X PspB PF06667.12 GAM18160.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.4 2 0 0 2 2 1 0 Phage shock protein B SprA-related PF12118.8 GAM18160.1 - 0.43 9.7 23.9 0.67 9.0 23.9 1.2 1 0 0 1 1 1 0 SprA-related family Neur_chan_memb PF02932.16 GAM18160.1 - 0.45 10.5 5.6 0.92 9.5 5.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 GAM18160.1 - 0.46 9.4 2.7 0.67 8.8 2.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.13 GAM18160.1 - 0.52 10.2 22.4 0.79 9.7 22.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 GAM18160.1 - 0.56 10.2 12.4 0.9 9.5 12.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Peptidase_S49_N PF08496.10 GAM18160.1 - 0.97 9.5 8.3 27 4.8 9.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Hydin_ADK PF17213.3 GAM18160.1 - 1.8 8.8 12.9 3.7 7.8 12.9 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF3464 PF11947.8 GAM18160.1 - 5.5 6.7 6.5 7.9 6.2 5.6 1.7 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 SelP_N PF04592.14 GAM18160.1 - 6.1 6.2 25.3 16 4.8 21.1 2.4 2 1 0 2 2 2 0 Selenoprotein P, N terminal region PBP_sp32 PF07222.12 GAM18160.1 - 6.4 6.2 14.8 11 5.4 14.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF1980 PF09323.10 GAM18160.1 - 7.2 6.5 7.4 63 3.4 7.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Androgen_recep PF02166.16 GAM18160.1 - 9 5.0 20.2 16 4.2 20.2 1.4 1 0 0 1 1 1 0 Androgen receptor ArenaCapSnatch PF17296.2 GAM18161.1 - 0.0026 17.2 0.2 0.009 15.5 0.0 1.8 1 1 1 2 2 2 1 Arenavirus cap snatching domain CDC45 PF02724.14 GAM18161.1 - 0.013 13.8 10.9 0.02 13.2 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4718 PF15842.5 GAM18161.1 - 0.09 12.6 4.6 1.6 8.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) YL1 PF05764.13 GAM18161.1 - 7.5 6.6 23.7 2.6 8.1 15.4 2.5 2 0 0 2 2 2 0 YL1 nuclear protein Sec20 PF03908.13 GAM18162.1 - 5.6e-15 55.0 2.7 5.6e-15 55.0 2.7 2.6 2 1 0 2 2 2 1 Sec20 DUF2721 PF11026.8 GAM18162.1 - 0.1 12.5 1.7 0.13 12.2 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) GARP PF16731.5 GAM18162.1 - 0.19 11.4 1.8 0.36 10.5 0.1 2.0 2 1 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma CHDCT2 PF08074.11 GAM18162.1 - 0.21 11.8 5.0 0.18 12.0 3.4 1.6 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Allexi_40kDa PF05549.11 GAM18162.1 - 5 6.6 9.9 2.3 7.7 1.9 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein 7TM_GPCR_Srj PF10319.9 GAM18162.1 - 5.1 6.4 7.4 0.13 11.6 0.4 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srj CHCH PF06747.13 GAM18163.1 - 0.00074 19.6 0.8 0.002 18.2 0.8 1.8 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 GAM18163.1 - 0.0018 18.2 6.1 0.012 15.6 1.7 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UCR_hinge PF02320.16 GAM18163.1 - 0.24 11.7 6.1 1 9.6 5.6 2.2 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Pkinase PF00069.25 GAM18164.1 - 2.8e-58 197.4 0.0 1e-57 195.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18164.1 - 4.2e-25 88.5 0.1 1.2e-17 64.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAM18164.1 - 0.0014 18.0 0.3 0.19 11.0 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 GAM18164.1 - 0.0039 16.3 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 GAM18164.1 - 0.0057 16.6 0.1 0.018 15.0 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM18164.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Apt1 PF10351.9 GAM18164.1 - 0.035 13.0 18.6 0.21 10.4 4.2 2.4 2 1 0 2 2 2 0 Golgi-body localisation protein domain Haspin_kinase PF12330.8 GAM18164.1 - 0.063 12.2 0.0 0.063 12.2 0.0 2.5 3 0 0 3 3 3 0 Haspin like kinase domain SOG2 PF10428.9 GAM18164.1 - 4.6 6.3 44.1 2 7.6 15.2 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Radical_SAM_N PF08497.10 GAM18165.1 - 0.056 12.7 4.3 0.065 12.5 4.3 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal DUF4407 PF14362.6 GAM18165.1 - 0.25 10.6 11.1 0.31 10.4 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2126 PF09899.9 GAM18165.1 - 0.36 8.9 11.8 0.51 8.3 11.8 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PAT1 PF09770.9 GAM18165.1 - 0.36 9.0 26.2 0.46 8.7 26.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PRCC PF10253.9 GAM18165.1 - 0.4 11.5 31.8 0.58 10.9 31.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting TFIIA PF03153.13 GAM18165.1 - 0.45 10.5 48.2 0.59 10.1 48.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.11 GAM18165.1 - 0.47 8.7 13.1 0.61 8.3 13.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDK5_activator PF03261.15 GAM18165.1 - 2 7.9 27.2 2.4 7.6 27.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Connexin PF00029.19 GAM18165.1 - 3.7 7.2 9.5 7.3 6.3 9.5 1.4 1 0 0 1 1 1 0 Connexin G_path_suppress PF15991.5 GAM18165.1 - 5.4 7.1 37.1 7.6 6.6 37.1 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor Hamartin PF04388.12 GAM18165.1 - 6.3 5.3 30.3 8 5.0 30.3 1.1 1 0 0 1 1 1 0 Hamartin protein LAP1C PF05609.12 GAM18165.1 - 6.6 5.7 24.9 8.2 5.4 24.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RNase_PH PF01138.21 GAM18166.1 - 3.9e-31 108.3 0.1 5.6e-31 107.8 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAM18166.1 - 1.4e-05 25.0 0.2 3.4e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Dor1 PF04124.12 GAM18167.1 - 3.2e-77 259.5 10.6 3.8e-77 259.3 10.6 1.0 1 0 0 1 1 1 1 Dor1-like family Exo84_C PF16528.5 GAM18167.1 - 8.8e-11 42.0 1.3 8.8e-11 42.0 1.3 2.5 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps54_N PF10475.9 GAM18167.1 - 5.3e-05 22.7 7.6 9.4e-05 21.8 7.6 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Sec5 PF15469.6 GAM18167.1 - 0.00012 21.9 6.6 0.00035 20.4 6.6 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 GAM18167.1 - 0.037 14.1 9.9 0.052 13.6 3.0 2.6 2 0 0 2 2 2 0 Vps51/Vps67 DUF19 PF01579.18 GAM18167.1 - 0.081 12.7 1.9 0.16 11.7 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF19) Sec8_exocyst PF04048.14 GAM18167.1 - 0.11 12.4 3.4 0.12 12.3 0.3 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Edc3_linker PF16598.5 GAM18167.1 - 0.52 11.0 4.6 5.1 7.8 1.0 2.6 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 CPL PF08144.11 GAM18168.1 - 5.9e-14 52.6 0.0 5.9e-14 52.6 0.0 4.0 3 2 1 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 GAM18168.1 - 0.00069 19.2 0.1 11 5.9 0.0 6.0 6 0 0 6 6 6 1 Pumilio-family RNA binding repeat Post_transc_reg PF13797.6 GAM18168.1 - 0.0054 16.6 0.1 0.019 14.9 0.1 1.9 1 0 0 1 1 1 1 Post-transcriptional regulator BID PF06393.11 GAM18168.1 - 0.069 12.7 0.0 0.069 12.7 0.0 2.5 2 0 0 2 2 2 0 BH3 interacting domain (BID) DUF3439 PF11921.8 GAM18168.1 - 0.36 10.8 5.1 0.78 9.7 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SAC3 PF12209.8 GAM18168.1 - 1.1 9.5 5.1 34 4.7 0.1 4.6 4 1 1 5 5 5 0 Leucine permease transcriptional regulator helical domain CDC45 PF02724.14 GAM18168.1 - 2.2 6.4 18.8 4 5.6 18.8 1.3 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GAM18168.1 - 2.7 8.0 28.2 6.4 6.8 22.9 2.5 2 0 0 2 2 2 0 YL1 nuclear protein Rtf2 PF04641.12 GAM18169.1 - 1.4e-69 234.4 11.5 3.5e-69 233.1 11.5 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 GAM18169.1 - 0.0037 17.1 0.6 0.027 14.3 0.7 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 CCDC142 PF14923.6 GAM18169.1 - 0.031 13.0 5.1 0.055 12.2 5.1 1.3 1 0 0 1 1 1 0 Coiled-coil protein 142 zf-NOSIP PF15906.5 GAM18169.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Apt1 PF10351.9 GAM18169.1 - 0.23 10.3 15.6 0.3 9.9 15.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3439 PF11921.8 GAM18169.1 - 0.58 10.1 18.7 0.18 11.8 13.9 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) Menin PF05053.13 GAM18169.1 - 0.74 8.1 7.9 0.98 7.7 7.9 1.1 1 0 0 1 1 1 0 Menin Mucin PF01456.17 GAM18169.1 - 2.7 8.0 20.6 0.24 11.4 15.8 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Presenilin PF01080.17 GAM18169.1 - 8 5.1 13.4 12 4.6 13.4 1.2 1 0 0 1 1 1 0 Presenilin PBP1_TM PF14812.6 GAM18170.1 - 0.0022 18.3 6.7 0.0022 18.3 6.7 1.0 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 GAM18170.1 - 0.11 12.8 7.3 0.12 12.8 7.3 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PAC1 PF16094.5 GAM18170.1 - 0.58 9.3 2.5 0.58 9.3 2.5 1.0 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 NOA36 PF06524.12 GAM18170.1 - 1.1 8.5 5.2 1.1 8.5 5.2 1.0 1 0 0 1 1 1 0 NOA36 protein PAS_7 PF12860.7 GAM18171.1 - 0.7 10.1 3.0 2.2 8.5 0.2 2.8 2 0 0 2 2 2 0 PAS fold Tfb2 PF03849.14 GAM18172.1 - 3.3e-99 332.2 10.0 3.9e-99 332.0 10.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 GAM18172.1 - 3.5e-22 78.6 0.3 8.4e-22 77.4 0.3 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain DUF445 PF04286.12 GAM18172.1 - 0.063 13.1 1.7 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) FNIP PF05725.12 GAM18173.1 - 4.7e-86 282.7 30.8 6e-13 48.7 0.3 9.9 5 2 5 11 11 11 11 FNIP Repeat HOCHOB PF17943.1 GAM18175.1 - 0.047 14.4 0.7 8.1 7.2 0.1 2.7 2 1 0 2 2 2 0 Homeobox-cysteine loop-homeobox WD40 PF00400.32 GAM18177.1 - 4.6e-08 33.6 35.2 0.032 15.1 0.7 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat C1_2 PF03107.16 GAM18177.1 - 0.00049 20.4 5.0 0.0014 18.9 5.0 1.8 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 GAM18177.1 - 0.0061 16.4 11.3 0.015 15.2 11.3 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ANAPC4_WD40 PF12894.7 GAM18177.1 - 0.0084 16.4 1.8 13 6.2 0.0 4.4 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Zn_Tnp_IS1595 PF12760.7 GAM18177.1 - 0.32 11.0 2.5 0.71 9.9 2.5 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain RNHCP PF12647.7 GAM18177.1 - 0.71 9.9 7.0 1.8 8.6 7.0 1.6 1 0 0 1 1 1 0 RNHCP domain zf-RING_2 PF13639.6 GAM18177.1 - 4.4 7.7 6.9 17 5.8 6.9 2.1 1 0 0 1 1 1 0 Ring finger domain CDI PF02234.19 GAM18178.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor RasGEF PF00617.19 GAM18179.1 - 2.8e-50 171.0 0.5 6.1e-50 169.9 0.5 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM18179.1 - 8.4e-21 74.2 0.3 8.4e-21 74.2 0.3 2.7 3 0 0 3 3 3 1 RasGEF N-terminal motif DEP PF00610.21 GAM18179.1 - 1e-15 57.5 0.0 2.4e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ammonium_transp PF00909.21 GAM18180.1 - 1.8e-48 165.3 23.8 2.2e-48 164.9 23.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Kinocilin PF15033.6 GAM18180.1 - 0.068 12.8 2.8 0.14 11.8 0.5 2.4 1 1 0 2 2 2 0 Kinocilin protein DUF1003 PF06210.11 GAM18180.1 - 0.24 11.5 3.0 2.8 8.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) TraL PF07178.11 GAM18180.1 - 7.9 7.0 0.0 7.9 7.0 0.0 4.2 4 1 1 5 5 5 0 TraL protein CBM_35 PF16990.5 GAM18181.1 - 0.03 14.6 0.8 0.054 13.8 0.1 1.7 2 0 0 2 2 2 0 Carbohydrate binding module (family 35) Big_3 PF07523.12 GAM18181.1 - 0.9 9.9 4.6 0.67 10.3 1.6 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) SprB PF13573.6 GAM18182.1 - 0.013 15.3 4.1 0.013 15.3 4.1 5.4 5 0 0 5 5 5 0 SprB repeat HSP70 PF00012.20 GAM18183.1 - 7.7e-136 453.7 0.0 9.2e-136 453.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM18183.1 - 6.6e-07 28.4 0.0 1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein SnoaL_2 PF12680.7 GAM18184.1 - 6.1e-07 30.0 0.0 6.8e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain DNA_pol3_delta2 PF13177.6 GAM18184.1 - 0.018 14.8 0.1 0.022 14.5 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF4440 PF14534.6 GAM18184.1 - 0.054 13.9 0.0 0.057 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) p450 PF00067.22 GAM18185.1 - 1.2e-104 350.7 1.2 1.4e-104 350.5 1.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 AhpC-TSA PF00578.21 GAM18186.1 - 7.1e-43 145.5 0.0 9.9e-43 145.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAM18186.1 - 9.9e-27 93.5 0.0 1.3e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 GAM18186.1 - 0.00011 22.3 0.1 0.00075 19.6 0.0 1.9 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme SCO1-SenC PF02630.14 GAM18186.1 - 0.0023 17.9 0.1 0.006 16.5 0.1 1.7 1 1 0 1 1 1 1 SCO1/SenC DUF899 PF05988.12 GAM18186.1 - 0.0055 16.3 0.0 0.007 15.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) GSHPx PF00255.19 GAM18186.1 - 0.031 13.8 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase YajC PF02699.15 GAM18186.1 - 0.067 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit Nucleoside_tran PF01733.18 GAM18186.1 - 0.13 11.7 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Nucleoside transporter WD40 PF00400.32 GAM18187.1 - 1.4e-41 139.6 29.3 6.8e-05 23.6 0.1 12.1 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM18187.1 - 4.3e-10 39.7 5.6 1.6 9.0 0.1 7.2 5 1 0 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM18187.1 - 4.3e-06 25.9 3.5 0.0014 17.6 0.0 5.0 5 1 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAM18187.1 - 0.0032 16.1 0.2 0.094 11.2 0.0 2.9 2 1 1 3 3 3 1 Cytochrome D1 heme domain ABC2_membrane PF01061.24 GAM18188.1 - 2.4e-84 282.0 58.3 2.5e-45 154.5 21.4 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAM18188.1 - 3.2e-49 167.0 0.1 1.8e-23 83.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM18188.1 - 3.4e-09 36.5 0.1 0.00014 21.3 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAM18188.1 - 6.9e-08 32.6 0.4 0.00094 19.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 GAM18188.1 - 1e-06 29.3 0.1 0.014 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 GAM18188.1 - 1.1e-06 28.4 0.8 0.069 13.1 0.1 3.1 3 0 0 3 3 2 2 CDR ABC transporter AAA_16 PF13191.6 GAM18188.1 - 2.4e-06 28.1 0.0 0.074 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAM18188.1 - 3.8e-06 26.9 0.1 0.67 9.7 0.1 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAM18188.1 - 5.1e-06 26.8 0.0 0.084 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 GAM18188.1 - 1.2e-05 25.4 0.3 0.18 11.7 0.0 3.0 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_33 PF13671.6 GAM18188.1 - 1.3e-05 25.4 0.1 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 GAM18188.1 - 1.6e-05 25.4 0.0 0.011 16.2 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAM18188.1 - 4.2e-05 23.2 0.0 0.069 12.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAM18188.1 - 6.7e-05 22.6 1.7 0.004 16.9 0.2 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 GAM18188.1 - 0.00012 22.5 0.0 0.88 10.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 GAM18188.1 - 0.00024 21.4 1.2 0.57 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 GAM18188.1 - 0.00058 19.6 2.5 0.052 13.3 0.2 3.4 2 0 0 2 2 2 1 Plant PDR ABC transporter associated DUF815 PF05673.13 GAM18188.1 - 0.00098 18.4 0.2 0.014 14.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 GAM18188.1 - 0.0014 17.9 0.3 0.14 11.4 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 GAM18188.1 - 0.0017 18.9 1.9 1.4 9.4 0.1 2.9 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 GAM18188.1 - 0.0018 18.2 0.6 0.99 9.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 GAM18188.1 - 0.0019 18.3 0.3 1.3 9.1 0.1 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_30 PF13604.6 GAM18188.1 - 0.0029 17.3 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAM18188.1 - 0.0038 17.0 0.1 5.1 6.8 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.14 GAM18188.1 - 0.0063 16.5 1.2 0.94 9.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAM18188.1 - 0.0089 15.6 0.1 0.57 9.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_17 PF13207.6 GAM18188.1 - 0.01 16.3 0.0 7.4 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 GAM18188.1 - 0.015 15.5 0.1 11 6.3 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 GAM18188.1 - 0.018 14.9 0.0 5.8 6.7 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 GAM18188.1 - 0.026 14.7 0.8 1 9.7 0.0 3.4 4 0 0 4 4 2 0 Putative exonuclease SbcCD, C subunit TsaE PF02367.17 GAM18188.1 - 0.028 14.4 0.3 6.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 GAM18188.1 - 0.045 13.5 0.6 3.5 7.4 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 GAM18188.1 - 0.049 13.2 1.0 4.3 6.9 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 GAM18188.1 - 0.11 11.7 0.3 3.4 6.7 0.0 2.5 2 1 1 3 3 3 0 G-protein alpha subunit Mg_chelatase PF01078.21 GAM18188.1 - 0.17 11.2 0.6 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 GAM18188.1 - 0.17 11.6 0.3 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 GAM18188.1 - 0.19 11.5 0.6 10 5.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF2070 PF09843.9 GAM18188.1 - 2 6.6 25.0 0.048 12.0 9.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) FNIP PF05725.12 GAM18189.1 - 5.5e-53 176.9 15.2 5.1e-11 42.6 0.1 8.9 7 2 0 8 8 8 7 FNIP Repeat CENP-B_dimeris PF09026.10 GAM18189.1 - 0.042 14.2 5.2 0.081 13.3 3.8 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3246 PF11596.8 GAM18189.1 - 0.053 12.9 1.5 0.08 12.4 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) OATP PF03137.20 GAM18190.1 - 0.0014 17.0 0.1 0.0026 16.1 0.1 1.4 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF3464 PF11947.8 GAM18190.1 - 0.0024 17.6 0.1 0.069 12.9 0.2 2.3 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 Connexin PF00029.19 GAM18190.1 - 0.018 14.8 0.2 0.028 14.2 0.2 1.4 1 0 0 1 1 1 0 Connexin LAP1C PF05609.12 GAM18190.1 - 0.021 14.0 1.7 0.056 12.5 1.2 1.8 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) U1snRNP70_N PF12220.8 GAM18190.1 - 0.062 14.0 5.1 0.12 13.0 5.1 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SARAF PF06682.12 GAM18190.1 - 0.66 9.6 4.5 0.13 11.9 0.3 1.9 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis EMC3_TMCO1 PF01956.16 GAM18190.1 - 0.93 9.2 8.4 0.8 9.4 6.9 1.7 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Peptidase_S49_N PF08496.10 GAM18190.1 - 7.7 6.6 8.2 18 5.3 8.2 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Flavodoxin_1 PF00258.25 GAM18192.1 - 2.6e-25 89.3 0.0 4.1e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 GAM18192.1 - 0.095 12.9 0.1 0.55 10.5 0.1 2.0 1 1 1 2 2 2 0 Flavodoxin domain FAD_binding_1 PF00667.20 GAM18193.1 - 4.2e-35 121.3 0.0 5.4e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GAM18193.1 - 1.5e-09 38.4 0.0 3.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2613 PF11021.8 GAM18195.1 - 0.017 15.2 1.4 4.9 7.3 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Big_7 PF17957.1 GAM18195.1 - 0.27 12.1 0.2 0.27 12.1 0.2 2.9 3 1 0 3 3 3 0 Bacterial Ig domain MeaB PF03308.16 GAM18196.1 - 0.011 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SAM_1 PF00536.30 GAM18196.1 - 0.012 16.1 0.1 0.056 13.9 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) NACHT PF05729.12 GAM18196.1 - 0.028 14.4 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.18 GAM18196.1 - 0.056 12.8 0.0 0.099 12.0 0.0 1.4 1 1 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 GAM18196.1 - 0.077 13.4 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SAM_3 PF18016.1 GAM18196.1 - 0.085 12.7 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AAA_22 PF13401.6 GAM18196.1 - 0.16 12.2 0.0 0.77 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain SAM_2 PF07647.17 GAM18196.1 - 0.17 12.0 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DDE_3 PF13358.6 GAM18197.1 - 2.9e-24 85.5 0.0 4.7e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease U3_assoc_6 PF08640.11 GAM18198.1 - 1e-15 57.6 1.3 1e-15 57.6 1.3 3.0 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 GAM18198.1 - 0.00021 21.8 1.0 34 5.6 0.2 5.4 4 1 2 6 6 6 1 Tetratricopeptide repeat KIX_2 PF16987.5 GAM18198.1 - 0.0052 16.8 0.3 0.052 13.5 0.0 2.5 2 0 0 2 2 2 1 KIX domain NRDE-2 PF08424.10 GAM18198.1 - 0.013 14.6 1.9 4.2 6.4 0.1 3.0 3 1 0 3 3 3 0 NRDE-2, necessary for RNA interference DPPIV_N PF00930.21 GAM18199.1 - 6.1e-71 239.0 7.2 1.3e-70 237.9 7.2 1.5 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 GAM18199.1 - 4.8e-47 160.2 0.0 1e-46 159.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 GAM18199.1 - 4.7e-09 36.2 1.3 4.1e-07 29.9 0.2 3.0 2 1 0 2 2 2 1 Putative esterase Peptidase_S15 PF02129.18 GAM18199.1 - 2.3e-07 30.7 0.2 3.1e-05 23.7 0.1 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 GAM18199.1 - 0.0026 16.5 0.0 0.48 9.1 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 GAM18199.1 - 0.01 16.5 0.1 0.033 14.8 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 GAM18199.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PD40 PF07676.12 GAM18199.1 - 0.012 15.6 0.3 0.18 11.8 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF5605 PF18310.1 GAM18199.1 - 0.019 14.9 0.6 0.24 11.3 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) DUF2974 PF11187.8 GAM18199.1 - 0.043 13.4 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase PF07224.11 GAM18199.1 - 0.057 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF3141 PF11339.8 GAM18199.1 - 0.12 10.8 0.1 0.18 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DLH PF01738.18 GAM18199.1 - 0.19 11.2 0.0 0.99 8.9 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Nucleoporin_FG PF13634.6 GAM18200.1 - 0.009 16.8 30.9 0.009 16.8 30.9 11.5 5 3 7 12 12 12 3 Nucleoporin FG repeat region DUF3656 PF12392.8 GAM18200.1 - 0.1 13.3 0.3 0.38 11.4 0.3 1.9 1 0 0 1 1 1 0 Collagenase FH2 PF02181.23 GAM18201.1 - 1.2e-80 271.5 7.9 1.2e-80 271.5 7.9 3.1 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 GAM18201.1 - 5e-34 117.6 0.4 5e-34 117.6 0.4 2.5 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 GAM18201.1 - 6.1e-23 81.3 0.3 1.7e-22 79.9 0.3 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Macoilin PF09726.9 GAM18201.1 - 0.00027 19.7 1.8 0.00027 19.7 1.8 1.8 2 0 0 2 2 2 1 Macoilin family GAS PF13851.6 GAM18201.1 - 0.49 9.7 9.4 4.2 6.7 0.5 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Leu_zip PF15294.6 GAM18201.1 - 0.69 9.4 10.1 0.1 12.1 4.5 2.2 2 0 0 2 2 2 0 Leucine zipper DUF1664 PF07889.12 GAM18201.1 - 1.6 8.7 7.5 26 4.9 1.7 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 GAM18201.1 - 6.9 6.9 10.4 5.8 7.2 4.2 3.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FNIP PF05725.12 GAM18202.1 - 1.7e-20 72.9 11.3 6.6e-14 51.8 0.9 5.3 3 2 0 5 5 5 4 FNIP Repeat ArsP_1 PF03773.13 GAM18203.1 - 0.11 11.7 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Predicted permease KSHV_K1 PF11049.8 GAM18204.1 - 0.033 14.1 0.3 0.09 12.7 0.1 1.8 2 0 0 2 2 2 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus SAM_3 PF18016.1 GAM18205.1 - 8.1e-08 32.0 0.1 1.8e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DAP3 PF10236.9 GAM18205.1 - 0.00098 18.4 0.0 0.0035 16.6 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 GAM18205.1 - 0.0019 18.6 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 GAM18205.1 - 0.0089 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_6 PF12774.7 GAM18205.1 - 0.014 14.4 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 GAM18205.1 - 0.024 15.0 0.0 0.055 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 GAM18205.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 GAM18205.1 - 0.076 12.9 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 GAM18205.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAM18205.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RlaP PF10127.9 GAM18210.1 - 1.5e-35 122.9 0.4 4.4e-24 85.4 0.1 2.3 2 1 0 2 2 2 2 RNA repair pathway DNA polymerase beta family Kelch_6 PF13964.6 GAM18213.1 - 4.3e-10 39.5 4.3 8.9e-05 22.6 0.0 4.5 3 1 1 4 4 4 2 Kelch motif Kelch_3 PF13415.6 GAM18213.1 - 2.8e-07 30.7 0.3 0.0013 19.0 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM18213.1 - 0.00014 21.8 14.1 0.0029 17.6 0.0 4.9 4 3 1 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM18213.1 - 0.00017 21.1 12.1 0.0038 16.8 0.0 4.0 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 GAM18213.1 - 0.0021 18.0 2.7 0.23 11.5 0.1 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 GAM18213.1 - 0.018 15.0 1.4 16 5.7 0.0 3.9 4 0 0 4 4 4 0 Kelch motif KxDL PF10241.9 GAM18213.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein Med7 PF05983.11 GAM18214.1 - 1.3e-57 195.0 15.6 1.3e-57 195.0 15.6 2.4 2 1 0 2 2 2 1 MED7 protein DUF842 PF05811.13 GAM18214.1 - 0.008 15.9 0.9 0.017 14.8 0.9 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF3439 PF11921.8 GAM18214.1 - 0.016 15.2 18.0 0.41 10.6 5.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ribosomal_L10 PF00466.20 GAM18214.1 - 0.11 12.7 1.5 0.29 11.3 1.5 1.7 1 0 0 1 1 1 0 Ribosomal protein L10 ParE-like_toxin PF15781.5 GAM18214.1 - 0.13 12.2 0.1 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 ParE-like toxin of type II bacterial toxin-antitoxin system DUF3618 PF12277.8 GAM18214.1 - 0.14 12.4 0.4 0.23 11.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) Mucin PF01456.17 GAM18214.1 - 0.38 10.7 32.3 0.57 10.2 9.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein TMPIT PF07851.13 GAM18214.1 - 0.46 9.7 5.3 2.7 7.1 3.4 2.1 1 1 2 3 3 3 0 TMPIT-like protein SSP160 PF06933.11 GAM18214.1 - 0.57 8.3 25.3 1 7.5 9.4 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Ecl1 PF12855.7 GAM18214.1 - 1.8 9.7 33.3 6 8.0 13.9 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins PPTA PF01239.22 GAM18215.1 - 1e-39 133.1 20.0 1.8e-08 33.9 0.3 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat YjbR PF04237.13 GAM18215.1 - 0.023 15.2 4.0 0.49 11.0 0.3 3.1 2 2 1 3 3 3 0 YjbR TPR_17 PF13431.6 GAM18215.1 - 0.12 12.8 0.2 5.4 7.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 GAM18216.1 - 1.7e-11 45.1 0.1 2.3e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 GAM18216.1 - 8.3e-05 22.4 0.1 0.0001 22.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM18216.1 - 0.0013 18.0 0.1 0.016 14.5 0.1 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM18216.1 - 0.0036 17.0 1.5 0.026 14.2 1.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 GAM18216.1 - 0.077 12.8 0.0 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase DUF1786 PF08735.10 GAM18216.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) PGAP1 PF07819.13 GAM18216.1 - 0.16 11.7 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein CW_7 PF08230.11 GAM18216.1 - 3.7 7.4 4.9 1.5 8.7 1.2 2.2 2 1 0 2 2 2 0 CW_7 repeat Cse1 PF08506.10 GAM18217.1 - 4.7e-108 361.3 6.2 1.1e-107 360.2 6.2 1.6 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 GAM18217.1 - 6.7e-88 295.1 2.9 6.7e-88 295.1 2.9 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 GAM18217.1 - 4.2e-13 49.0 0.8 1.2e-11 44.4 0.3 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GAM18217.1 - 0.02 15.0 0.1 0.02 15.0 0.1 4.7 4 1 0 5 5 5 0 Exportin 1-like protein DUF3437 PF11919.8 GAM18217.1 - 0.091 12.7 0.4 7.1 6.6 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) DEAD PF00270.29 GAM18218.1 - 9.6e-45 152.5 0.3 1.4e-44 152.0 0.3 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM18218.1 - 5.3e-28 97.6 2.5 2.1e-27 95.7 0.5 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM18218.1 - 2.6e-06 27.5 0.0 3.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UPF0227 PF05728.12 GAM18218.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Dickkopf_N PF04706.12 GAM18220.1 - 0.0036 17.8 4.9 0.0036 17.8 4.9 6.2 5 2 1 6 6 6 2 Dickkopf N-terminal cysteine-rich region HlyIII PF03006.20 GAM18221.1 - 9.8e-30 103.9 16.1 1.3e-29 103.5 16.1 1.2 1 0 0 1 1 1 1 Haemolysin-III related UAA PF08449.11 GAM18222.1 - 2e-59 201.3 19.7 2.8e-59 200.8 19.7 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAM18222.1 - 7.2e-07 29.5 26.9 0.00069 19.8 9.9 2.8 2 1 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 GAM18222.1 - 0.00054 19.3 8.3 0.00054 19.3 8.3 2.7 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport TPT PF03151.16 GAM18222.1 - 0.0016 17.8 13.9 0.058 12.7 5.2 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF979 PF06166.12 GAM18222.1 - 0.028 13.6 0.3 0.028 13.6 0.3 2.3 2 1 0 3 3 3 0 Protein of unknown function (DUF979) SdrD_B PF17210.3 GAM18225.1 - 1.6e-31 108.8 66.4 5.8e-13 49.1 0.8 8.5 7 1 1 8 8 8 6 SdrD B-like domain DUF2012 PF09430.10 GAM18225.1 - 0.00012 22.2 0.0 16 5.6 0.0 4.6 4 0 0 4 4 4 2 Protein of unknown function (DUF2012) DUF2141 PF09912.9 GAM18225.1 - 0.00091 19.1 0.9 5.3 7.0 0.0 5.0 6 0 0 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2141) Y_Y_Y PF07495.13 GAM18225.1 - 0.0018 18.2 3.2 2.8 8.0 0.4 4.7 4 0 0 4 4 4 1 Y_Y_Y domain Gal_mutarotas_2 PF13802.6 GAM18225.1 - 0.076 13.3 0.2 37 4.7 0.0 3.4 3 0 0 3 3 3 0 Galactose mutarotase-like Glyco_transf_8 PF01501.20 GAM18226.1 - 2.6e-09 37.0 3.0 5.8e-09 35.9 3.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAM18226.1 - 0.0014 18.0 0.1 0.0022 17.4 0.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Vel1p PF10339.9 GAM18226.1 - 0.14 11.5 0.4 0.6 9.5 0.1 1.9 2 0 0 2 2 2 0 Yeast-specific zinc responsive Pantoate_transf PF02548.15 GAM18227.1 - 3.1e-112 374.2 4.0 4e-112 373.8 2.4 2.0 2 1 1 3 3 3 1 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.11 GAM18227.1 - 4.2e-32 111.0 0.1 1.5e-31 109.2 0.1 2.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 GAM18227.1 - 8e-29 100.3 2.1 1.1e-28 99.8 0.1 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 GAM18227.1 - 7.7e-05 22.7 0.3 0.00027 20.9 0.3 1.9 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PEP_mutase PF13714.6 GAM18227.1 - 0.00031 20.3 0.1 0.0014 18.1 0.1 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Shikimate_DH PF01488.20 GAM18227.1 - 0.018 15.1 0.3 0.083 13.0 0.0 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAM18227.1 - 0.034 14.4 0.9 0.13 12.5 0.0 2.5 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain HTH_6 PF01418.17 GAM18227.1 - 0.056 13.4 4.4 0.23 11.5 4.4 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Fib_alpha PF08702.10 GAM18227.1 - 0.24 11.6 2.9 0.62 10.2 2.9 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family 3HCDH_N PF02737.18 GAM18227.1 - 0.26 11.1 0.0 0.26 11.1 0.0 2.8 3 1 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RhoGEF PF00621.20 GAM18228.1 - 1.2e-45 156.0 2.1 1.2e-45 156.0 2.1 1.6 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 GAM18228.1 - 4.6e-20 71.5 10.6 1.1e-19 70.3 10.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 GAM18228.1 - 5.1e-10 39.8 0.3 1.4e-09 38.4 0.3 1.8 1 0 0 1 1 1 1 PH domain Ribonuclease_3 PF00636.26 GAM18228.1 - 0.0054 17.3 0.2 0.036 14.7 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease III domain PH_13 PF16652.5 GAM18228.1 - 0.0055 16.5 0.4 0.028 14.2 0.4 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 GAM18228.1 - 0.16 12.1 0.8 20 5.4 0.1 2.6 3 0 0 3 3 3 0 PH domain DUF3268 PF11672.8 GAM18228.1 - 0.41 11.0 3.8 0.85 10.0 3.8 1.5 1 0 0 1 1 1 0 zinc-finger-containing domain DZR PF12773.7 GAM18228.1 - 0.49 10.5 8.8 7.4 6.7 0.5 2.7 1 1 1 2 2 2 0 Double zinc ribbon SdrD_B PF17210.3 GAM18229.1 - 9.7e-34 116.0 25.4 9.5e-10 38.7 0.4 4.6 4 1 0 4 4 4 4 SdrD B-like domain SpaA PF17802.1 GAM18229.1 - 7.5e-07 29.4 10.3 0.53 10.7 0.1 4.7 3 2 0 3 3 3 2 Prealbumin-like fold domain Y_Y_Y PF07495.13 GAM18229.1 - 3.9e-06 26.7 0.3 0.18 11.8 0.0 4.3 3 0 0 3 3 3 2 Y_Y_Y domain Cna_B PF05738.13 GAM18229.1 - 1.9e-05 25.1 4.5 0.92 10.1 0.0 4.3 4 0 0 4 4 4 1 Cna protein B-type domain DUF2012 PF09430.10 GAM18229.1 - 3e-05 24.1 0.0 0.31 11.2 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF2012) DUF3244 PF11589.8 GAM18229.1 - 0.00061 19.8 1.0 0.58 10.3 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3244) Interfer-bind PF09294.10 GAM18229.1 - 0.0048 17.2 0.7 21 5.5 0.0 5.0 4 3 1 5 5 5 0 Interferon-alpha/beta receptor, fibronectin type III DUF2141 PF09912.9 GAM18229.1 - 0.011 15.7 1.2 15 5.6 0.0 4.4 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2141) Nuc_N PF14448.6 GAM18229.1 - 0.19 11.6 0.0 0.78 9.6 0.0 2.0 2 0 0 2 2 2 0 Nuclease N terminal DUF1439 PF07273.12 GAM18229.1 - 0.36 10.7 0.8 10 6.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1439) DUF3810 PF12725.7 GAM18230.1 - 0.0032 16.9 2.2 0.0032 16.9 2.2 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3810) ApoO PF09769.9 GAM18230.1 - 0.085 12.8 1.1 0.27 11.2 1.1 1.8 1 0 0 1 1 1 0 Apolipoprotein O ODV-E18 PF10717.9 GAM18230.1 - 0.5 10.3 3.2 2.2 8.2 0.0 3.1 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Tim17 PF02466.19 GAM18231.1 - 1.3e-06 28.8 1.5 2.1e-06 28.1 1.3 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 GAM18231.1 - 0.024 14.4 2.4 3.2 7.6 0.8 2.5 2 1 0 2 2 2 0 YMGG-like Gly-zipper ATPase_gene1 PF09527.10 GAM18231.1 - 3.8 7.7 7.9 1.1 9.5 1.6 2.5 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Endosulfine PF04667.17 GAM18232.1 - 3.2e-05 24.0 0.2 0.00013 22.0 0.2 1.9 1 1 1 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region tRNA-synt_2d PF01409.20 GAM18233.1 - 1.3e-86 290.1 0.0 1.7e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 GAM18233.1 - 3.1e-07 30.6 0.3 6.5e-07 29.5 0.3 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 GAM18233.1 - 1.3e-06 28.0 0.0 5.3e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 GAM18233.1 - 5.3e-05 22.4 0.0 0.00031 19.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Arm PF00514.23 GAM18234.1 - 7.7e-24 82.9 11.4 1.1e-05 25.3 0.0 8.6 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAM18234.1 - 1.6e-06 28.5 0.2 3.3 8.3 0.0 5.0 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 GAM18234.1 - 0.00018 21.5 0.1 10 6.7 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat DUF3361 PF11841.8 GAM18234.1 - 0.00033 20.6 4.3 0.093 12.7 0.0 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF3361) HEAT_2 PF13646.6 GAM18234.1 - 0.00053 20.3 0.0 0.93 9.9 0.0 4.2 2 2 3 5 5 5 1 HEAT repeats RICTOR_V PF14668.6 GAM18234.1 - 0.0025 18.0 1.9 11 6.3 0.0 5.1 5 1 1 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 BAF250_C PF12031.8 GAM18234.1 - 0.007 15.7 0.0 0.22 10.8 0.0 2.7 2 1 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa Mo25 PF08569.11 GAM18234.1 - 0.073 12.4 0.1 0.073 12.4 0.1 2.0 2 0 0 2 2 2 0 Mo25-like FoP_duplication PF13865.6 GAM18234.1 - 5.1 7.7 7.1 10 6.7 0.2 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Thiolase_N PF00108.23 GAM18235.1 - 5e-88 294.8 2.6 9.2e-88 294.0 1.6 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM18235.1 - 3.6e-44 149.4 0.6 6.3e-44 148.6 0.6 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAM18235.1 - 0.00037 20.2 0.5 0.0016 18.0 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 GAM18235.1 - 0.015 15.4 0.0 0.055 13.6 0.0 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 GAM18235.1 - 0.095 12.6 2.9 0.43 10.5 0.1 3.1 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PseudoU_synth_1 PF01416.20 GAM18236.1 - 5.2e-09 36.5 0.0 1.2e-06 29.0 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase SprT-like PF10263.9 GAM18237.1 - 1.8e-11 43.9 0.0 6.1e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 SprT-like family Tubulin PF00091.25 GAM18238.1 - 1.2e-38 133.4 0.3 1.9e-38 132.7 0.3 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 GAM18238.1 - 8.2e-23 80.5 0.0 2.3e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 GAM18238.1 - 5.5e-05 22.5 5.2 0.0019 17.5 0.6 2.7 1 1 1 2 2 2 2 Tubulin like DUF4147 PF13660.6 GAM18238.1 - 0.023 14.2 0.2 0.048 13.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Sugar-bind PF04198.13 GAM18238.1 - 0.057 12.6 0.4 0.17 11.0 0.1 1.8 2 0 0 2 2 2 0 Putative sugar-binding domain Ribonuclease_3 PF00636.26 GAM18239.1 - 1.3e-36 125.4 0.1 1.8e-17 63.8 0.0 3.9 2 2 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAM18239.1 - 1.7e-34 118.8 0.1 1.5e-16 60.7 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease-III-like dsrm PF00035.26 GAM18239.1 - 2.2e-10 41.1 0.3 4.9e-10 40.0 0.3 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 GAM18239.1 - 0.00021 21.5 0.0 0.00061 20.0 0.0 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Cep57_CLD PF14073.6 GAM18239.1 - 0.014 15.4 1.9 0.026 14.6 1.9 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Methyltransf_11 PF08241.12 GAM18239.1 - 0.058 14.0 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain F-box PF00646.33 GAM18240.1 - 1.1 9.2 4.4 0.47 10.4 0.3 2.5 3 0 0 3 3 3 0 F-box domain GCV_T PF01571.21 GAM18241.1 - 3e-85 285.7 0.0 3.8e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 GAM18241.1 - 2.5e-16 59.3 0.0 4.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 GAM18241.1 - 9.2e-06 25.9 0.1 4.8e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family DUF3659 PF12396.8 GAM18241.1 - 0.11 12.4 0.1 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Pirin PF02678.16 GAM18243.1 - 7.7e-29 99.8 0.1 1.1e-28 99.3 0.1 1.2 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 GAM18243.1 - 4.7e-09 36.5 0.0 5.2e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 GAM18243.1 - 0.00011 21.8 0.4 0.021 14.6 0.5 2.3 2 0 0 2 2 2 2 Cupin domain Ank_2 PF12796.7 GAM18244.1 - 2.2e-24 85.8 12.5 0.001 19.6 0.2 6.8 3 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM18244.1 - 1e-20 73.8 16.7 0.0032 18.0 0.1 8.5 7 3 3 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM18244.1 - 1.1e-16 60.6 8.3 1.9 8.9 0.0 10.5 5 2 5 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM18244.1 - 5.6e-16 57.0 3.9 4.5 8.2 0.1 11.3 11 1 1 12 12 12 4 Ankyrin repeat DUF3447 PF11929.8 GAM18244.1 - 0.00048 20.0 9.7 0.0026 17.7 0.0 4.8 5 1 0 6 6 6 1 Domain of unknown function (DUF3447) DUF5049 PF16468.5 GAM18244.1 - 0.0015 18.4 0.0 6.4 6.8 0.0 5.2 6 0 0 6 6 6 1 Domain of unknown function (DUF5049) Ank PF00023.30 GAM18244.1 - 0.14 12.7 5.5 2.1e+02 2.6 0.0 6.8 6 2 1 7 7 7 0 Ankyrin repeat PhoPQ_related PF10142.9 GAM18245.1 - 8e-134 445.9 2.4 9.4e-134 445.7 2.4 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Ribosomal_L25p PF01386.19 GAM18246.1 - 3e-06 27.6 0.1 7.1e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L25p family Collectrin PF16959.5 GAM18246.1 - 0.023 14.4 0.4 0.036 13.9 0.4 1.3 1 0 0 1 1 1 0 Renal amino acid transporter AAA_22 PF13401.6 GAM18247.1 - 4.5e-12 46.4 0.0 1.2e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAM18247.1 - 1.5e-10 41.6 0.0 3.7e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 GAM18247.1 - 3e-08 33.5 0.2 3.2e-07 30.2 0.0 2.6 2 1 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_16 PF13191.6 GAM18247.1 - 2.5e-05 24.7 0.0 5.5e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 GAM18247.1 - 0.00045 19.6 0.0 0.00071 18.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 GAM18247.1 - 0.0013 18.2 0.1 0.0022 17.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein DEAD PF00270.29 GAM18247.1 - 0.0085 15.9 1.1 1.8 8.3 0.1 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase AAA_7 PF12775.7 GAM18247.1 - 0.023 14.2 0.1 0.047 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DNA_pol3_delta2 PF13177.6 GAM18247.1 - 0.025 14.3 0.1 0.055 13.3 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF4154 PF13689.6 GAM18247.1 - 0.026 14.7 0.0 0.67 10.2 0.0 2.6 2 0 0 2 2 2 0 YfiR/HmsC-like GvpD PF07088.11 GAM18247.1 - 0.027 13.1 0.0 0.045 12.4 0.0 1.4 1 0 0 1 1 1 0 GvpD gas vesicle protein KdpD PF02702.17 GAM18247.1 - 0.051 13.0 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain AAA_32 PF13654.6 GAM18247.1 - 0.07 11.9 0.1 0.14 10.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GAM18247.1 - 0.081 12.9 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAM18247.1 - 0.11 12.2 0.1 0.33 10.7 0.0 1.9 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 GAM18247.1 - 0.12 12.7 0.4 0.28 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain GATA PF00320.27 GAM18248.1 - 1.3e-12 47.1 0.7 2e-12 46.5 0.7 1.3 1 0 0 1 1 1 1 GATA zinc finger Calpain_III PF01067.22 GAM18249.1 - 3.3e-39 134.4 2.8 1.2e-17 64.4 0.0 4.5 4 1 1 5 5 5 3 Calpain large subunit, domain III C2 PF00168.30 GAM18249.1 - 4.1e-06 27.0 0.1 4.1e-06 27.0 0.1 3.2 3 2 2 5 5 5 1 C2 domain DUF1296 PF06972.11 GAM18251.1 - 2.2e-05 24.5 0.0 4.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) ADP_ribosyl_GH PF03747.14 GAM18252.1 - 1.5e-49 169.3 0.1 1.9e-49 169.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Med14 PF08638.11 GAM18253.1 - 7.3e-45 152.7 3.4 4.8e-30 104.4 0.0 3.2 1 1 1 2 2 2 2 Mediator complex subunit MED14 DUF2722 PF10846.8 GAM18253.1 - 0.0001 21.4 2.3 0.0001 21.4 2.3 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 GAM18253.1 - 0.0063 16.2 14.3 0.0063 16.2 14.3 4.5 4 1 0 4 4 4 1 Spt20 family EPL1 PF10513.9 GAM18253.1 - 0.47 10.8 15.7 0.3 11.5 1.3 2.8 2 0 0 2 2 2 0 Enhancer of polycomb-like TFIIA PF03153.13 GAM18253.1 - 0.71 9.8 40.9 0.011 15.7 9.5 2.9 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Histone PF00125.24 GAM18254.1 - 3.6e-48 163.2 3.9 4e-48 163.1 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAM18254.1 - 2.8e-05 24.2 0.9 4.6e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAM18254.1 - 2.8e-05 24.4 0.1 4.6e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 GAM18254.1 - 0.00063 20.3 1.3 0.00083 20.0 1.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 GAM18254.1 - 0.026 14.6 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HisKA PF00512.25 GAM18254.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Epimerase PF01370.21 GAM18255.1 - 1.8e-21 76.7 0.3 3.3e-21 75.9 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM18255.1 - 1.1e-14 54.2 0.2 3.4e-13 49.4 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 GAM18255.1 - 1.2e-14 54.0 0.0 1.7e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM18255.1 - 1.6e-11 44.2 0.1 2.2e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM18255.1 - 1.4e-09 38.1 0.0 1.9e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM18255.1 - 1.1e-07 31.6 0.1 1.8e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 GAM18255.1 - 0.00042 19.5 0.2 0.00079 18.6 0.2 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAM18255.1 - 0.00059 19.1 0.0 0.00094 18.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAM18255.1 - 0.0063 16.4 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 GAM18255.1 - 0.043 13.3 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase DUF2209 PF09974.9 GAM18255.1 - 0.098 13.0 0.2 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) Pkinase PF00069.25 GAM18256.1 - 6.2e-64 215.9 0.2 6.2e-64 215.9 0.2 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18256.1 - 1.3e-42 145.9 0.0 1.3e-42 145.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM18256.1 - 0.0025 17.2 0.0 0.011 15.1 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAM18256.1 - 0.0041 16.0 0.0 0.0041 16.0 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 GAM18256.1 - 0.046 13.6 0.1 0.14 12.0 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family DLIC PF05783.11 GAM18256.1 - 0.051 12.4 0.7 0.073 11.9 0.7 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Seadorna_VP7 PF07387.11 GAM18256.1 - 0.11 11.5 0.1 0.11 11.5 0.1 2.2 3 0 0 3 3 3 0 Seadornavirus VP7 FAM76 PF16046.5 GAM18256.1 - 2.5 7.4 6.8 0.32 10.3 2.7 1.5 2 0 0 2 2 2 0 FAM76 protein Ribosomal_L35Ae PF01247.18 GAM18257.1 - 2.4e-37 127.0 0.1 2.7e-37 126.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 GAM18257.1 - 0.059 13.6 0.0 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain RPEL PF02755.15 GAM18260.1 - 8.6e-11 41.2 33.0 1.3e-06 27.9 1.2 8.3 9 0 0 9 9 9 6 RPEL repeat SKA2 PF16740.5 GAM18261.1 - 9e-16 57.6 1.0 9e-16 57.6 1.0 2.3 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 DUF3161 PF11362.8 GAM18261.1 - 3.1e-09 36.7 0.1 6.9e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3161) SKA1 PF07160.12 GAM18261.1 - 9.4e-06 25.6 11.3 2.3e-05 24.3 11.3 1.7 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Pathogen_betaC1 PF09593.10 GAM18261.1 - 0.075 13.0 0.4 0.34 10.9 0.1 2.0 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein ToxS PF17323.2 GAM18263.1 - 0.16 11.6 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Trans-membrane regulatory protein ToxS LRR_4 PF12799.7 GAM18263.1 - 0.46 11.0 4.7 43 4.7 1.8 3.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) AP-5_subunit_s1 PF15001.6 GAM18264.1 - 1.3e-23 84.0 1.2 3.4e-18 66.4 0.2 2.4 2 1 0 2 2 2 2 AP-5 complex subunit sigma-1 Clat_adaptor_s PF01217.20 GAM18264.1 - 0.002 18.1 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2183 PF09949.9 GAM18264.1 - 0.12 12.7 0.4 4 7.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) CBM49 PF09478.10 GAM18265.1 - 7.3e-20 71.1 1.4 9.7e-20 70.7 1.4 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 EGF_MSP1_1 PF12946.7 GAM18265.1 - 0.45 10.6 3.8 1.1 9.4 3.8 1.7 1 0 0 1 1 1 0 MSP1 EGF domain 1 Snurportin1 PF11538.8 GAM18266.1 - 0.00027 21.1 3.7 0.00027 21.1 3.7 2.0 2 0 0 2 2 2 1 Snurportin1 PSK_trans_fac PF07704.11 GAM18266.1 - 1.2 9.9 5.2 0.9 10.3 1.7 2.3 2 0 0 2 2 2 0 Rv0623-like transcription factor Peptidase_S9 PF00326.21 GAM18267.1 - 3.7e-07 29.9 0.1 6.9e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAM18267.1 - 0.00022 21.9 0.2 0.00057 20.6 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family RRN3 PF05327.11 GAM18269.1 - 0.61 8.6 14.6 1 7.9 14.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 GAM18269.1 - 1.8 6.8 8.7 2.5 6.3 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAM18269.1 - 7.5 4.5 20.5 11 4.0 20.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ecl1 PF12855.7 GAM18270.1 - 2.6 9.2 30.1 0.16 13.1 10.5 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Dicty_REP PF05086.12 GAM18270.1 - 7.9 4.3 34.4 0.26 9.2 6.6 2.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Pox_RNA_Pol_22 PF05273.13 GAM18271.1 - 0.12 12.1 1.0 0.56 9.9 0.4 2.1 1 1 1 2 2 2 0 Poxvirus RNA polymerase 22 kDa subunit Ribosomal_L29 PF00831.23 GAM18271.1 - 0.15 12.1 0.3 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Ribosomal L29 protein IL2RB_N1 PF18707.1 GAM18272.1 - 0.18 12.4 5.6 0.23 12.0 5.6 1.2 1 0 0 1 1 1 0 Interleukin-2 receptor subunit beta N-terminal domain 1 LRR_4 PF12799.7 GAM18273.1 - 3.4 8.2 5.9 55 4.4 1.9 3.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) DUF1258 PF06869.12 GAM18275.1 - 0.14 11.6 1.6 1.9 7.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) Pkinase PF00069.25 GAM18277.1 - 6.7e-70 235.5 0.0 9.2e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18277.1 - 1.7e-34 119.2 0.2 2.8e-34 118.6 0.2 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM18277.1 - 2.7e-05 23.6 0.5 0.00059 19.2 0.1 2.5 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 GAM18277.1 - 0.0016 17.9 0.8 0.0024 17.3 0.8 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM18277.1 - 0.057 13.3 0.0 3.5 7.5 0.0 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM18277.1 - 0.22 10.4 8.1 0.017 14.1 2.7 1.8 2 1 0 2 2 2 0 Haspin like kinase domain Inositol_P PF00459.25 GAM18278.1 - 2.6e-69 233.8 0.0 3.1e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PI3Ka PF00613.20 GAM18279.1 - 8.7e-54 181.7 1.5 1.8e-53 180.7 1.5 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 GAM18279.1 - 2.3e-53 181.6 0.0 8.3e-52 176.5 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 GAM18279.1 - 4.2e-21 75.3 0.0 9.4e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 GAM18279.1 - 1e-12 48.1 3.3 5.8e-10 39.3 0.1 3.5 2 1 1 3 3 3 2 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 GAM18279.1 - 0.0019 17.6 0.6 0.0096 15.3 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4135) Histone PF00125.24 GAM18280.1 - 9.4e-21 74.5 5.4 1.2e-20 74.2 5.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAM18280.1 - 0.0088 16.3 0.4 0.0088 16.3 0.4 2.2 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 GAM18280.1 - 0.024 15.0 0.1 0.048 14.0 0.1 1.5 1 0 0 1 1 1 0 CENP-S protein CNP_C_terminal PF17839.1 GAM18280.1 - 0.047 14.4 0.4 0.09 13.5 0.4 1.4 1 0 0 1 1 1 0 C-terminal domain of cyclic nucleotide phosphodiesterase MATalpha_HMGbox PF04769.12 GAM18280.1 - 0.055 12.8 1.7 0.078 12.3 1.4 1.3 1 1 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box PIP5K PF01504.18 GAM18281.1 - 5.6e-71 239.0 9.5 8.7e-71 238.3 9.5 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Dicty_CAR PF05462.11 GAM18281.1 - 5.9e-16 58.5 9.7 1.1e-15 57.6 9.7 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Frizzled PF01534.17 GAM18281.1 - 7.5e-13 48.2 15.0 4.2e-12 45.8 15.0 2.0 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_1 PF00001.21 GAM18281.1 - 4.7e-09 36.0 4.6 1e-08 34.9 4.6 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 GAM18281.1 - 4.5e-08 32.7 7.3 7.9e-08 31.9 7.3 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.9 GAM18281.1 - 0.0022 17.4 6.8 0.0035 16.7 6.8 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx RED_N PF07808.13 GAM18281.1 - 0.027 14.1 6.2 0.046 13.3 6.2 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region STE3 PF02076.15 GAM18281.1 - 0.33 10.1 13.3 0.29 10.3 11.1 2.0 2 0 0 2 2 2 0 Pheromone A receptor Dcc1 PF09724.9 GAM18282.1 - 1.7e-72 244.5 0.0 2e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Peptidase_C1 PF00112.23 GAM18283.1 - 2.2e-47 161.9 8.9 2.9e-47 161.6 8.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAM18283.1 - 0.0015 17.4 0.9 0.098 11.4 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C39_2 PF13529.6 GAM18283.1 - 0.0031 18.1 1.3 0.005 17.4 0.5 1.9 2 0 0 2 2 2 1 Peptidase_C39 like family DUF4106 PF13388.6 GAM18283.1 - 0.17 11.1 15.1 0.25 10.5 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) BtrH_N PF14399.6 GAM18283.1 - 0.18 12.0 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal DUF3482 PF11981.8 GAM18284.1 - 0.054 12.9 1.0 0.077 12.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Inhibitor_I29 PF08246.12 GAM18284.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.6 1 1 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Pentapeptide_4 PF13599.6 GAM18285.1 - 2.7e-15 56.3 25.3 4.6e-09 36.3 14.7 3.5 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 GAM18285.1 - 3.2e-13 49.0 22.0 7e-05 22.4 5.0 4.5 2 2 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 GAM18285.1 - 2.7e-07 30.6 16.0 2.3e-06 27.7 7.2 4.0 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) zf-RING_2 PF13639.6 GAM18285.1 - 0.0021 18.3 15.1 0.0021 18.3 15.1 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAM18285.1 - 3.8 7.4 20.9 1.5 8.8 14.2 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 GAM18285.1 - 3.9 7.7 14.5 0.61 10.3 9.1 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 GAM18285.1 - 6 7.0 17.3 1.2 9.3 11.8 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAM18285.1 - 6.6 6.7 19.1 3.1 7.7 14.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4380 PF14315.6 GAM18286.1 - 0.00034 19.6 0.0 0.0006 18.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4380) dsDNA_bind PF01984.20 GAM18287.1 - 2.3e-29 101.9 10.4 2.6e-29 101.7 10.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Glyco_trans_1_4 PF13692.6 GAM18288.1 - 0.057 13.9 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 PCYCGC PF13798.6 GAM18288.1 - 0.15 11.9 0.5 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif DUF1980 PF09323.10 GAM18288.1 - 0.41 10.5 4.3 3.1 7.7 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Aconitase PF00330.20 GAM18289.1 - 1.1e-179 598.3 0.0 1.4e-179 597.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAM18289.1 - 1.4e-37 129.0 0.0 2.6e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain CH PF00307.31 GAM18290.1 - 3.1e-20 72.4 0.0 8.2e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM18290.1 - 5.9e-08 32.4 0.1 1.2e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CH_2 PF06294.11 GAM18290.1 - 0.026 14.6 0.0 0.079 13.1 0.0 1.8 1 0 0 1 1 1 0 CH-like domain in sperm protein Cortex-I_coil PF09304.10 GAM18290.1 - 4.7 7.5 189.4 0.38 11.0 4.9 16.8 2 1 12 14 14 14 0 Cortexillin I, coiled coil FYVE PF01363.21 GAM18291.1 - 5.3e-18 64.9 8.3 1.2e-17 63.8 8.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger Arrestin_C PF02752.22 GAM18291.1 - 4e-07 30.5 2.3 0.0072 16.8 0.0 3.9 2 2 1 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAM18291.1 - 6.9e-05 22.9 2.3 0.0038 17.3 0.1 3.5 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain TMEM171 PF15471.6 GAM18291.1 - 0.0014 17.7 1.9 0.0027 16.8 1.9 1.4 1 0 0 1 1 1 1 Transmembrane protein family 171 Rgp1 PF08737.10 GAM18291.1 - 0.006 15.8 3.0 0.034 13.3 0.0 2.7 3 0 0 3 3 3 1 Rgp1 CCD48 PF15799.5 GAM18291.1 - 0.11 10.8 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 zf-RING_5 PF14634.6 GAM18291.1 - 0.45 10.5 10.4 1.1 9.3 10.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 GAM18291.1 - 2.4 8.6 10.3 9.9 6.6 10.2 2.1 1 1 1 2 2 2 0 Ring finger domain Secretin_N_2 PF07655.13 GAM18291.1 - 7.9 7.1 31.4 0.64 10.6 14.3 2.9 3 0 0 3 3 3 0 Secretin N-terminal domain eIF-5a PF01287.20 GAM18292.1 - 4.7e-27 93.9 0.1 7.1e-27 93.3 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 GAM18292.1 - 0.00031 20.7 0.1 0.00046 20.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain PCMD PF13201.6 GAM18292.1 - 0.025 14.4 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Putative carbohydrate metabolism domain Glyco_transf_20 PF00982.21 GAM18293.1 - 4e-141 470.9 0.0 6.4e-141 470.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAM18293.1 - 6.8e-59 198.8 0.0 9.9e-59 198.3 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 GAM18293.1 - 0.0006 19.6 0.0 0.19 11.5 0.1 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.6 GAM18294.1 - 9.8e-10 38.6 14.4 1.7e-09 37.8 14.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAM18294.1 - 1e-09 38.1 10.7 1.6e-09 37.4 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM18294.1 - 5e-09 35.8 13.4 1.4e-08 34.4 13.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM18294.1 - 5.8e-08 32.5 14.2 1.3e-07 31.4 14.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM18294.1 - 2.2e-06 27.5 13.4 1.3e-05 25.1 13.8 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM18294.1 - 6.6e-06 26.1 11.4 2e-05 24.5 11.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAM18294.1 - 9.3e-06 25.4 14.2 0.00031 20.5 14.8 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAM18294.1 - 8.7e-05 22.7 13.8 8.7e-05 22.7 13.8 2.5 2 1 1 3 3 3 1 RING-H2 zinc finger domain Spt20 PF12090.8 GAM18294.1 - 0.0043 16.7 13.7 0.0066 16.1 13.7 1.4 1 0 0 1 1 1 1 Spt20 family TMEM51 PF15345.6 GAM18294.1 - 0.014 15.2 2.2 0.018 14.9 2.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3597 PF12200.8 GAM18294.1 - 0.024 15.2 1.0 0.036 14.6 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) zf-C3HC4_4 PF15227.6 GAM18294.1 - 0.036 14.2 11.2 0.19 11.9 11.2 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 GAM18294.1 - 0.041 13.9 5.3 0.11 12.5 5.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 GAM18294.1 - 0.062 13.0 6.3 0.15 11.8 6.3 1.7 1 0 0 1 1 1 0 P-11 zinc finger DUF2722 PF10846.8 GAM18294.1 - 0.089 11.7 12.3 0.12 11.3 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Folliculin PF11704.8 GAM18294.1 - 0.09 12.6 6.6 0.12 12.3 6.0 1.5 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport zf-RING_6 PF14835.6 GAM18294.1 - 0.096 12.6 6.6 0.26 11.2 6.6 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Presenilin PF01080.17 GAM18294.1 - 0.33 9.7 3.3 0.39 9.4 3.3 1.1 1 0 0 1 1 1 0 Presenilin RecR PF02132.15 GAM18294.1 - 0.58 9.8 7.7 2.2 7.9 2.2 2.7 3 0 0 3 3 3 0 RecR protein zf-RING_4 PF14570.6 GAM18294.1 - 0.63 9.9 13.9 2.8 7.8 14.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TerY_C PF15616.6 GAM18294.1 - 0.94 9.6 13.4 0.11 12.6 8.6 2.1 2 1 1 3 3 2 0 TerY-C metal binding domain Activator_LAG-3 PF11498.8 GAM18294.1 - 1.4 7.8 21.6 1.9 7.4 21.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EIIBC-GUT_N PF03612.14 GAM18294.1 - 1.5 8.5 4.3 2.6 7.7 4.3 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus UPF0258 PF06789.12 GAM18294.1 - 3.1 7.9 7.6 8 6.6 6.3 2.1 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0258) DUF4834 PF16118.5 GAM18294.1 - 7 7.7 9.3 1.7 9.7 6.0 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) ELO PF01151.18 GAM18295.1 - 2.9e-53 181.0 23.0 3.5e-53 180.7 23.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family FH2 PF02181.23 GAM18296.1 - 1.1e-82 278.2 2.3 1.4e-82 277.8 2.3 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain MNE1 PF13762.6 GAM18296.1 - 0.03 14.3 1.3 0.071 13.1 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component Sec61_beta PF03911.16 GAM18297.1 - 2.2e-17 62.8 0.2 2.5e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family Thioredoxin PF00085.20 GAM18298.1 - 4.5e-43 145.4 9.2 1.4e-25 89.2 0.5 4.0 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 GAM18298.1 - 7.5e-32 110.7 7.9 4.4e-31 108.2 1.2 3.2 1 1 1 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.17 GAM18298.1 - 2.3e-11 43.4 4.2 8.6e-11 41.5 0.5 2.8 1 1 1 3 3 3 1 Calsequestrin Thioredoxin_2 PF13098.6 GAM18298.1 - 8.9e-09 35.8 3.5 0.0035 17.8 0.1 3.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAM18298.1 - 1.4e-08 34.7 0.4 0.0081 16.3 0.1 2.9 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 GAM18298.1 - 7.3e-07 28.8 1.7 0.0061 15.9 0.1 3.8 4 0 0 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GAM18298.1 - 7.6e-07 29.4 4.0 0.018 15.3 0.0 5.4 3 3 3 6 6 6 2 Thioredoxin-like AhpC-TSA PF00578.21 GAM18298.1 - 0.0037 17.2 1.1 2 8.4 0.2 3.0 3 1 0 3 3 3 2 AhpC/TSA family Cbl_N2 PF02761.14 GAM18298.1 - 0.042 14.5 0.1 0.66 10.7 0.0 2.8 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain Glutaredoxin PF00462.24 GAM18298.1 - 0.11 12.7 0.9 37 4.7 0.0 3.3 2 0 0 2 2 2 0 Glutaredoxin GCD14 PF08704.10 GAM18299.1 - 1.7e-98 329.3 0.0 2e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 GAM18299.1 - 7e-07 29.2 0.0 1.7e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 GAM18299.1 - 3.8e-05 23.5 0.0 8.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_25 PF13649.6 GAM18299.1 - 0.00034 21.2 0.0 0.00081 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 GAM18299.1 - 0.0017 19.4 0.0 0.0033 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 GAM18299.1 - 0.0076 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 GAM18299.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-C4H2 PF10146.9 GAM18300.1 - 1.8e-05 25.2 44.4 0.005 17.2 15.0 4.5 2 1 0 3 3 3 2 Zinc finger-containing protein Spc7 PF08317.11 GAM18300.1 - 0.0012 17.8 25.7 0.0012 17.8 25.7 4.2 2 1 1 4 4 4 2 Spc7 kinetochore protein ZapB PF06005.12 GAM18300.1 - 0.0034 17.8 5.7 0.0034 17.8 5.7 7.0 3 2 2 5 5 3 2 Cell division protein ZapB GAS PF13851.6 GAM18300.1 - 0.0052 16.1 11.1 0.0052 16.1 11.1 5.1 3 1 2 5 5 5 2 Growth-arrest specific micro-tubule binding Tup_N PF08581.10 GAM18300.1 - 0.0098 16.2 2.3 0.0098 16.2 2.3 6.3 4 2 2 6 6 6 1 Tup N-terminal Filament PF00038.21 GAM18300.1 - 0.016 14.8 2.1 0.016 14.8 2.1 3.3 2 1 0 2 2 1 0 Intermediate filament protein DDE_Tnp_IS66_C PF13817.6 GAM18300.1 - 0.078 13.2 0.0 0.36 11.1 0.0 2.2 1 0 0 1 1 1 0 IS66 C-terminal element Bap31_Bap29_C PF18035.1 GAM18300.1 - 0.13 12.3 0.0 0.13 12.3 0.0 6.7 5 2 1 6 6 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain RuvB_C PF05491.13 GAM18300.1 - 0.27 11.2 5.6 0.95 9.4 0.2 3.2 3 0 0 3 3 3 0 RuvB C-terminal winged helix domain HOOK PF05622.12 GAM18300.1 - 1.7 6.7 64.1 0.39 8.8 5.5 3.2 1 1 2 3 3 3 0 HOOK protein WD40_alt PF14077.6 GAM18300.1 - 3.6 7.5 9.5 11 6.0 0.4 3.6 3 0 0 3 3 3 0 Alternative WD40 repeat motif Yop-YscD_cpl PF16697.5 GAM18301.1 - 0.077 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain FXMRP1_C_core PF12235.8 GAM18301.1 - 1.5 9.5 7.7 1.2 9.7 6.0 1.7 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal PAT1 PF09770.9 GAM18301.1 - 8.2 4.6 13.5 9.5 4.3 13.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SP_C-Propep PF08999.10 GAM18302.1 - 9.2 6.1 10.5 15 5.4 10.5 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide BRCT_2 PF16589.5 GAM18303.1 - 8.1e-10 39.0 0.0 3.4e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAM18303.1 - 7e-05 23.1 0.0 0.063 13.7 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain CspB_prodomain PF18425.1 GAM18303.1 - 0.0026 17.7 0.1 0.0059 16.6 0.1 1.6 1 0 0 1 1 1 1 Csp protease B prodomain SWIRM-assoc_2 PF16496.5 GAM18303.1 - 0.012 14.5 1.4 0.018 14.0 1.4 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Dicty_REP PF05086.12 GAM18303.1 - 0.68 7.8 13.4 1.1 7.2 13.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Omega-toxin PF06357.11 GAM18303.1 - 7.2 6.5 5.5 1.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Omega-atracotoxin Ank_2 PF12796.7 GAM18304.1 - 9.7e-11 42.1 0.2 2.9e-06 27.8 0.0 5.7 4 2 1 6 6 6 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM18304.1 - 2e-07 31.4 12.3 0.0038 17.8 0.0 8.3 7 2 2 9 9 9 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM18304.1 - 5.5e-06 26.3 7.6 6 7.8 0.0 8.0 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 GAM18304.1 - 1e-05 25.7 1.6 3.9 7.9 0.0 5.7 4 1 2 6 6 6 1 Ankyrin repeats (many copies) DnaG_DnaB_bind PF08278.11 GAM18304.1 - 0.027 15.1 0.7 2.3 8.8 0.0 3.3 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding DNase_II PF03265.15 GAM18306.1 - 0.0042 16.4 0.4 0.0099 15.2 0.0 1.7 1 1 0 1 1 1 1 Deoxyribonuclease II THF_DHG_CYH_C PF02882.19 GAM18309.1 - 7.9e-71 236.5 5.1 7.9e-71 236.5 5.1 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 GAM18309.1 - 3e-38 130.6 0.8 4.9e-38 130.0 0.8 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 GAM18309.1 - 0.0062 15.5 0.8 0.0097 14.9 0.8 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family adh_short PF00106.25 GAM18309.1 - 0.021 14.3 0.2 0.048 13.1 0.2 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Xpo1 PF08389.12 GAM18310.1 - 9.5e-34 116.6 3.2 9.5e-34 116.6 3.2 4.5 5 2 1 6 6 6 1 Exportin 1-like protein Mei5_like PF17021.5 GAM18310.1 - 0.055 13.5 0.5 0.3 11.1 0.0 2.5 2 0 0 2 2 2 0 Putative double-strand recombination repair-like Ric8 PF10165.9 GAM18310.1 - 0.058 12.4 6.2 0.14 11.2 0.9 2.9 2 1 0 3 3 3 0 Guanine nucleotide exchange factor synembryn NAAA-beta PF15508.6 GAM18310.1 - 0.073 13.4 0.0 4.7 7.6 0.0 3.5 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TRAP-gamma PF07074.12 GAM18311.1 - 2.5e-30 105.2 10.1 3.1e-30 105.0 10.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) TRM13 PF05206.14 GAM18312.1 - 9.7e-68 228.5 4.0 1.6e-67 227.8 4.0 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 GAM18312.1 - 1.9e-09 37.2 1.3 4.6e-09 36.0 1.3 1.8 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 GAM18312.1 - 6.8e-06 25.7 4.3 6.8e-06 25.7 4.3 2.2 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein STAT_bind PF02864.15 GAM18312.1 - 0.065 13.8 1.8 0.15 12.6 0.2 2.5 2 0 0 2 2 2 0 STAT protein, DNA binding domain FNIP PF05725.12 GAM18313.1 - 1e-42 144.1 13.0 3.2e-13 49.6 1.3 5.2 4 1 0 5 5 5 4 FNIP Repeat Ank_2 PF12796.7 GAM18314.1 - 1.5e-07 31.9 4.9 0.00053 20.5 0.2 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM18314.1 - 1.1e-05 25.8 8.4 0.063 13.9 0.3 5.0 3 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM18314.1 - 0.17 12.5 9.6 4.9 8.1 0.0 5.9 6 0 0 6 6 6 0 Ankyrin repeat Sporozoite_P67 PF05642.11 GAM18317.1 - 0.0014 16.8 0.8 0.0017 16.6 0.8 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 GAM18317.1 - 0.0023 18.3 7.3 0.0036 17.6 7.3 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DUF4611 PF15387.6 GAM18317.1 - 0.0069 16.6 2.1 0.0096 16.1 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) FAM176 PF14851.6 GAM18317.1 - 0.0087 15.7 0.2 0.012 15.2 0.2 1.3 1 0 0 1 1 1 1 FAM176 family DNA_pol_phi PF04931.13 GAM18317.1 - 0.016 13.3 6.2 0.019 13.1 6.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 GAM18317.1 - 0.025 13.8 0.3 0.032 13.4 0.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tub_N PF16322.5 GAM18317.1 - 0.41 11.0 6.0 0.55 10.6 6.0 1.1 1 0 0 1 1 1 0 Tubby N-terminal Nop14 PF04147.12 GAM18317.1 - 0.46 8.6 7.3 0.58 8.3 7.3 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4538 PF15061.6 GAM18317.1 - 0.52 10.1 2.0 7.5 6.4 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) NOA36 PF06524.12 GAM18317.1 - 0.88 8.8 8.7 1.3 8.3 8.7 1.2 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 GAM18317.1 - 0.92 8.8 8.8 1.2 8.5 8.8 1.0 1 0 0 1 1 1 0 BUD22 PBP1_TM PF14812.6 GAM18317.1 - 0.98 9.8 7.2 1.6 9.2 7.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.13 GAM18317.1 - 1.1 9.0 5.8 1.5 8.6 5.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 GAM18317.1 - 3.1 6.0 7.8 4 5.6 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CAP_N PF01213.19 GAM18318.1 - 4.2e-98 328.7 0.3 5.6e-98 328.3 0.3 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 GAM18318.1 - 9.2e-63 210.6 8.5 1.4e-62 210.0 8.5 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 GAM18318.1 - 1.6e-05 24.6 6.2 4.6e-05 23.1 6.2 1.7 1 1 0 1 1 1 1 Tubulin binding cofactor C Ribosomal_60s PF00428.19 GAM18318.1 - 0.11 13.1 8.1 3.6 8.2 3.2 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein HSBP1 PF06825.12 GAM18318.1 - 0.17 11.8 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DEC-1_N PF04625.13 GAM18318.1 - 0.67 8.9 14.7 0.79 8.7 6.5 2.3 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region RhoGAP PF00620.27 GAM18319.1 - 6.1e-35 120.3 0.6 1.7e-33 115.6 0.1 3.1 2 1 1 3 3 3 1 RhoGAP domain RhoGEF PF00621.20 GAM18319.1 - 1.5e-30 106.8 0.4 5.9e-30 104.8 0.4 2.1 1 0 0 1 1 1 1 RhoGEF domain SdrD_B PF17210.3 GAM18319.1 - 4.9e-10 39.6 1.0 4.9e-10 39.6 1.0 2.3 2 0 0 2 2 2 1 SdrD B-like domain PH PF00169.29 GAM18319.1 - 7.5e-05 23.2 0.8 7.5e-05 23.2 0.8 3.2 4 0 0 4 4 4 1 PH domain CarboxypepD_reg PF13620.6 GAM18319.1 - 0.0041 17.4 0.0 0.0041 17.4 0.0 2.5 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 GAM18319.1 - 0.1 12.6 7.7 0.46 10.5 0.2 3.4 2 1 1 3 3 3 0 CarboxypepD_reg-like domain Arm-DNA-bind_1 PF09003.10 GAM18319.1 - 2.3 8.5 4.8 1.6 8.9 0.2 2.7 2 0 0 2 2 2 0 Bacteriophage lambda integrase, Arm DNA-binding domain PH_10 PF15411.6 GAM18319.1 - 8.4 6.7 6.5 1 9.6 0.4 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain DEAD PF00270.29 GAM18320.1 - 4.5e-45 153.6 0.0 4.5e-45 153.6 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM18320.1 - 2.5e-25 89.0 0.1 2.2e-24 85.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAM18320.1 - 2.5e-19 69.3 0.1 4.4e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DUF5127 PF17168.4 GAM18321.1 - 0.023 14.5 0.1 4.1 7.1 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5127) ATG16 PF08614.11 GAM18324.1 - 0.00016 22.0 11.6 0.027 14.7 7.0 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 GAM18324.1 - 0.00025 20.5 3.4 0.00043 19.7 3.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) PvlArgDC PF01862.16 GAM18324.1 - 0.067 13.0 0.6 0.16 11.8 0.2 1.8 2 0 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) gpW PF02831.15 GAM18324.1 - 0.48 10.4 1.9 26 4.8 0.1 2.5 2 0 0 2 2 2 0 gpW CLZ PF16526.5 GAM18324.1 - 0.89 10.0 6.1 0.93 9.9 1.1 3.1 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FliX PF10768.9 GAM18324.1 - 0.99 9.9 5.5 0.21 12.1 1.7 1.8 2 0 0 2 2 2 0 Class II flagellar assembly regulator TolA_bind_tri PF16331.5 GAM18324.1 - 1 9.5 5.8 3 8.0 0.1 3.5 3 2 1 4 4 4 0 TolA binding protein trimerisation MCM_bind PF09739.9 GAM18325.1 - 6.4e-166 553.2 12.3 7.2e-166 553.1 12.3 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Pkinase PF00069.25 GAM18326.1 - 1.2e-52 178.9 0.1 1.9e-52 178.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18326.1 - 1.9e-23 83.1 0.2 3.6e-22 78.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase PhnG PF06754.12 GAM18326.1 - 0.062 13.3 0.4 0.13 12.2 0.4 1.5 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG G-alpha PF00503.20 GAM18327.1 - 8.8e-102 340.9 4.6 1e-101 340.6 4.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM18327.1 - 5.1e-15 55.4 0.9 3e-10 39.8 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAM18327.1 - 0.0024 18.1 0.0 2.6 8.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAM18327.1 - 0.022 14.8 0.0 6.9 6.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.10 GAM18327.1 - 0.11 11.9 0.6 2 7.8 0.0 2.6 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF4089 PF13318.6 GAM18327.1 - 0.17 12.3 0.6 0.36 11.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) PIF1 PF05970.14 GAM18328.1 - 1.2e-59 202.3 2.5 6.6e-58 196.6 1.0 2.6 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 GAM18328.1 - 2.7e-17 63.1 0.0 2.2e-16 60.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain U-box PF04564.15 GAM18328.1 - 1e-11 44.8 1.0 6.8e-11 42.2 0.1 2.7 2 0 0 2 2 2 1 U-box domain AAA_19 PF13245.6 GAM18328.1 - 1.8e-10 41.3 0.0 6.3e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAM18328.1 - 4.5e-06 26.6 0.3 0.016 15.0 0.0 3.3 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 GAM18328.1 - 7.3e-06 25.8 0.1 1.7e-05 24.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 GAM18328.1 - 0.00013 21.8 0.1 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 GAM18328.1 - 0.00046 20.2 0.8 0.002 18.2 0.0 2.5 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 GAM18328.1 - 0.00055 19.9 0.3 0.025 14.5 0.2 2.5 2 0 0 2 2 2 1 NTPase AAA_7 PF12775.7 GAM18328.1 - 0.0011 18.5 0.8 0.0023 17.5 0.1 1.9 2 0 0 2 2 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 GAM18328.1 - 0.0052 17.1 0.1 0.03 14.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAM18328.1 - 0.0071 16.3 0.7 0.032 14.1 0.1 2.3 2 1 0 2 2 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GAM18328.1 - 0.0071 16.7 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain zf-NOSIP PF15906.5 GAM18328.1 - 0.012 15.7 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein AAA_29 PF13555.6 GAM18328.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 GAM18328.1 - 0.016 14.3 0.1 0.028 13.5 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 GAM18328.1 - 0.019 14.4 0.1 0.042 13.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 GAM18328.1 - 0.034 14.6 0.7 0.13 12.7 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 GAM18328.1 - 0.043 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.9 GAM18328.1 - 0.052 12.8 0.2 0.61 9.3 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 GAM18328.1 - 0.071 12.3 0.1 0.16 11.2 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 GAM18328.1 - 0.084 12.9 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 GAM18328.1 - 0.1 13.1 2.9 0.16 12.5 0.1 2.7 3 1 0 3 3 2 0 ABC transporter Sigma54_activat PF00158.26 GAM18328.1 - 0.12 12.1 0.1 0.36 10.5 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain Helicase_RecD PF05127.14 GAM18328.1 - 0.16 11.8 0.1 1.2 9.0 0.1 2.4 1 1 0 1 1 1 0 Helicase UvrD_C_2 PF13538.6 GAM18328.1 - 0.19 11.6 0.1 0.41 10.5 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF87 PF01935.17 GAM18328.1 - 3.5 7.7 6.4 3.1 7.9 0.1 3.5 2 2 2 4 4 4 0 Helicase HerA, central domain Abhydrolase_1 PF00561.20 GAM18329.1 - 1.2e-18 67.7 0.0 3e-16 59.8 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM18329.1 - 6.9e-18 66.1 0.0 8.2e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM18329.1 - 7.2e-09 35.3 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAM18329.1 - 1.4e-07 31.5 0.2 2.5e-06 27.4 0.2 2.1 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAM18329.1 - 7.9e-05 22.3 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 GAM18329.1 - 0.0003 20.5 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 GAM18329.1 - 0.00033 20.9 0.0 0.00043 20.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 GAM18329.1 - 0.0093 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.11 GAM18329.1 - 0.028 13.7 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase PF07224.11 GAM18329.1 - 0.043 12.8 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ndr PF03096.14 GAM18329.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family Nucleoporin2 PF04096.14 GAM18330.1 - 2.3e-45 154.3 0.0 4.5e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 GAM18330.1 - 0.0012 19.6 72.5 0.0031 18.3 26.3 10.4 4 2 6 10 10 10 3 Nucleoporin FG repeat region Nup96 PF12110.8 GAM18331.1 - 3.8e-70 236.3 1.5 3.8e-70 236.3 1.5 1.8 2 1 0 2 2 2 1 Nuclear protein 96 RnlA_toxin PF15935.5 GAM18331.1 - 0.04 13.7 4.4 0.19 11.5 0.3 2.8 2 2 0 2 2 2 0 RNase LS, bacterial toxin RPW8 PF05659.11 GAM18331.1 - 0.18 11.5 1.9 0.26 11.0 0.4 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF445 PF04286.12 GAM18331.1 - 1.1 9.0 5.2 1.5 8.6 2.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF445) DIL PF01843.19 GAM18332.1 - 1.5e-10 41.3 5.6 1.5e-10 41.2 3.8 2.0 3 0 0 3 3 3 1 DIL domain NT-C2 PF10358.9 GAM18332.1 - 2.2e-07 30.7 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Mito_carr PF00153.27 GAM18333.1 - 6e-10 38.9 0.2 0.00041 20.2 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein Ribosomal_S25 PF03297.15 GAM18334.1 - 1.7e-35 121.2 2.2 2e-35 121.0 2.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Rrf2 PF02082.20 GAM18334.1 - 0.12 12.7 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator RabGAP-TBC PF00566.18 GAM18336.1 - 1.1e-08 35.0 5.4 1.1e-08 35.0 5.4 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Dna2 PF08696.11 GAM18336.1 - 0.011 15.5 0.0 0.068 13.0 0.0 2.1 2 0 0 2 2 2 0 DNA replication factor Dna2 BRCT PF00533.26 GAM18337.1 - 0.00042 20.6 0.0 0.0019 18.6 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAM18337.1 - 0.00094 19.1 0.1 0.002 18.0 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain RRM_1 PF00076.22 GAM18337.1 - 0.0055 16.5 0.1 0.016 15.0 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRCT_2 PF16589.5 GAM18337.1 - 0.02 15.3 0.2 0.096 13.1 0.0 2.3 2 1 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain CENP-B_dimeris PF09026.10 GAM18338.1 - 0.0088 16.4 2.0 0.011 16.1 2.0 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain RRN3 PF05327.11 GAM18338.1 - 0.044 12.3 10.2 0.046 12.3 10.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 GAM18338.1 - 1.1 7.5 9.2 1.1 7.5 9.2 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 GAM18338.1 - 3.2 8.2 11.4 3.4 8.1 10.7 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RhoGAP PF00620.27 GAM18339.1 - 2e-38 131.6 0.3 3.1e-38 131.0 0.3 1.3 1 0 0 1 1 1 1 RhoGAP domain Pkinase PF00069.25 GAM18340.1 - 9e-44 149.8 1.7 2.8e-43 148.2 0.1 2.3 2 0 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.12 GAM18340.1 - 1.2e-38 132.1 2.5 1.2e-38 132.1 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 GAM18340.1 - 6.7e-26 91.1 0.0 1.3e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 GAM18340.1 - 2.4e-05 24.0 0.3 0.00087 18.9 0.0 2.9 2 1 0 2 2 2 1 PQQ-like domain Kinase-like PF14531.6 GAM18340.1 - 3.1e-05 23.4 0.0 5.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PQQ PF01011.21 GAM18340.1 - 0.005 16.7 0.2 3 7.9 0.1 3.3 3 0 0 3 3 3 1 PQQ enzyme repeat CLN3 PF02487.17 GAM18340.1 - 0.0051 15.9 3.7 0.0051 15.9 3.7 2.4 2 1 0 2 2 2 1 CLN3 protein Arif-1 PF06770.11 GAM18340.1 - 0.073 12.7 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) SID-1_RNA_chan PF13965.6 GAM18340.1 - 0.076 11.4 12.9 0.026 12.9 6.7 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 HK97-gp10_like PF04883.12 GAM18340.1 - 0.088 13.8 0.1 0.22 12.5 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Ac76 PF05814.11 GAM18340.1 - 0.15 12.1 4.7 0.16 12.0 0.9 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) TFIIA PF03153.13 GAM18340.1 - 0.18 11.8 26.7 1.3 8.9 4.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 GAM18340.1 - 0.71 8.6 17.9 1.3 7.7 9.5 2.3 2 0 0 2 2 2 0 Presenilin Pkinase_fungal PF17667.1 GAM18340.1 - 1.4 7.6 14.8 0.23 10.2 9.6 2.3 2 1 0 2 2 2 0 Fungal protein kinase Mitofilin PF09731.9 GAM18340.1 - 2.4 6.9 17.8 0.14 11.0 12.0 1.7 2 0 0 2 2 2 0 Mitochondrial inner membrane protein O-antigen_lig PF13425.6 GAM18340.1 - 2.7 6.7 15.8 0.71 8.6 4.8 2.3 2 0 0 2 2 2 0 O-antigen ligase like membrane protein PARP PF00644.20 GAM18341.1 - 4.2e-67 225.5 0.2 2.3e-66 223.1 0.0 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 GAM18341.1 - 1.3e-40 138.7 2.3 2.8e-40 137.6 2.3 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain PADR1 PF08063.12 GAM18341.1 - 7.4e-16 57.7 0.1 7.4e-16 57.7 0.1 1.9 2 0 0 2 2 2 1 PADR1 (NUC008) domain WGR PF05406.15 GAM18341.1 - 6.7e-14 51.7 0.6 1.7e-13 50.4 0.6 1.7 1 0 0 1 1 1 1 WGR domain zf-PARP PF00645.18 GAM18341.1 - 1.3e-10 41.9 0.1 5.1e-10 40.1 0.1 2.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region BRCT PF00533.26 GAM18341.1 - 0.0035 17.7 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM18341.1 - 0.099 13.1 0.1 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain ORC_WH_C PF18137.1 GAM18341.1 - 0.26 11.4 2.3 0.78 9.8 2.3 1.7 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal SCO1-SenC PF02630.14 GAM18344.1 - 3.2e-43 146.9 0.0 4.9e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 GAM18344.1 - 0.00059 20.1 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 GAM18344.1 - 0.00078 19.4 0.0 0.0017 18.3 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Folate_carrier PF01770.18 GAM18344.1 - 0.058 12.1 0.5 0.087 11.5 0.5 1.2 1 0 0 1 1 1 0 Reduced folate carrier EOS1 PF12326.8 GAM18344.1 - 0.11 12.4 1.4 0.22 11.4 1.4 1.4 1 0 0 1 1 1 0 N-glycosylation protein Presenilin PF01080.17 GAM18344.1 - 0.29 9.8 1.2 0.39 9.4 1.2 1.1 1 0 0 1 1 1 0 Presenilin Corazonin PF17308.2 GAM18344.1 - 0.7 10.3 9.3 1.3 9.4 9.3 1.3 1 0 0 1 1 1 0 Pro-corazonin MmgE_PrpD PF03972.14 GAM18345.1 - 4.2e-141 470.5 0.0 5e-141 470.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PMAIP1 PF15150.6 GAM18345.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced AAA_23 PF13476.6 GAM18346.1 - 0.0013 19.2 28.0 0.28 11.6 0.8 2.6 2 0 0 2 2 2 2 AAA domain EMP24_GP25L PF01105.24 GAM18347.1 - 1.1e-49 168.9 0.4 1.3e-49 168.6 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HMD PF03201.16 GAM18348.1 - 0.018 15.2 1.0 0.8 10.0 0.1 2.4 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase FNIP PF05725.12 GAM18349.1 - 5.4e-46 154.5 25.2 2e-10 40.6 0.1 10.4 7 3 2 10 10 10 9 FNIP Repeat ubiquitin PF00240.23 GAM18350.1 - 4.2e-34 116.1 0.4 6.5e-34 115.5 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 GAM18350.1 - 5.9e-23 80.8 1.6 5.9e-23 80.8 1.6 1.7 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 GAM18350.1 - 8.9e-16 57.5 0.4 1.5e-15 56.8 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAM18350.1 - 4.5e-05 23.8 0.1 0.00021 21.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM18350.1 - 0.0012 18.9 0.2 0.0026 17.8 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAM18350.1 - 0.0058 16.9 0.5 0.011 16.0 0.0 1.6 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAM18350.1 - 0.013 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 GAM18350.1 - 0.015 15.8 0.3 0.021 15.4 0.3 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain IBR PF01485.21 GAM18350.1 - 0.022 15.0 0.2 0.036 14.3 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 GAM18350.1 - 0.032 14.3 0.7 9.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain AAA_22 PF13401.6 GAM18351.1 - 7.1e-11 42.5 1.3 0.065 13.5 0.0 7.0 7 1 1 8 8 8 3 AAA domain AAA_7 PF12775.7 GAM18351.1 - 5.8e-10 39.0 1.0 0.012 15.1 0.0 4.9 4 0 0 4 4 4 4 P-loop containing dynein motor region AAA PF00004.29 GAM18351.1 - 7.9e-08 32.8 0.1 2.2e-05 24.9 0.0 4.7 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM18351.1 - 5.2e-05 23.7 0.0 0.4 11.0 0.0 4.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 GAM18351.1 - 0.0012 18.8 0.2 8.9 6.3 0.0 4.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAM18351.1 - 0.078 12.8 0.1 0.33 10.8 0.1 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 GAM18351.1 - 0.099 11.7 0.1 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 GAM18351.1 - 0.16 11.6 0.0 20 4.8 0.1 3.2 3 0 0 3 3 3 0 AAA domain PAP1 PF08601.10 GAM18351.1 - 2.1 8.0 16.8 4.4 6.9 16.8 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 DUF4363 PF14276.6 GAM18351.1 - 2.3 8.4 5.7 21 5.3 0.0 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) MFS_1 PF07690.16 GAM18353.1 - 7.4e-50 169.8 37.7 4.4e-40 137.7 14.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM18353.1 - 3.2e-07 29.6 5.4 3.2e-07 29.6 5.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 GAM18353.1 - 3.1e-06 25.8 8.6 0.00092 17.6 5.6 3.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family GWT1 PF06423.12 GAM18353.1 - 3 8.0 13.1 7.4 6.7 3.5 3.3 3 2 0 3 3 3 0 GWT1 ADH_N PF08240.12 GAM18355.1 - 1.4e-21 76.4 2.3 2.7e-21 75.5 2.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM18355.1 - 1e-20 74.0 0.1 1.7e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM18355.1 - 7.2e-05 23.9 0.0 0.00015 22.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Met_10 PF02475.16 GAM18355.1 - 0.005 16.6 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein AlaDh_PNT_C PF01262.21 GAM18355.1 - 0.0069 15.7 0.6 0.013 14.8 0.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 GAM18355.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain bZIP_1 PF00170.21 GAM18356.1 - 9.1e-12 44.9 4.8 1.5e-11 44.2 4.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM18356.1 - 2.9e-08 33.6 4.7 3.1e-08 33.5 3.3 1.7 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 GAM18356.1 - 0.0057 17.2 4.4 0.0084 16.6 4.4 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Nitrate_red_del PF02613.15 GAM18356.1 - 0.027 14.5 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase delta subunit PBP1_TM PF14812.6 GAM18356.1 - 5.1 7.5 8.2 6.4 7.2 7.5 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ldh_1_C PF02866.18 GAM18357.1 - 5.1e-37 127.4 0.2 9e-37 126.6 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAM18357.1 - 1.3e-33 116.1 0.5 2e-33 115.4 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Period_C PF12114.8 GAM18358.1 - 0.064 12.8 3.4 0.11 12.1 3.4 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SR-25 PF10500.9 GAM18358.1 - 0.78 9.3 5.9 1.2 8.6 5.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 GAM18358.1 - 4.4 8.0 8.3 8.2 7.2 8.3 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein TPT PF03151.16 GAM18360.1 - 1e-31 110.4 27.3 1.3e-31 110.1 27.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAM18360.1 - 2.3e-10 40.8 37.0 1.7e-06 28.2 14.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAM18360.1 - 2.9e-07 30.0 30.4 3.8e-07 29.6 30.4 1.1 1 0 0 1 1 1 1 UAA transporter family GET2 PF08690.10 GAM18360.1 - 0.0087 15.8 3.6 0.015 15.0 3.6 1.3 1 0 0 1 1 1 1 GET complex subunit GET2 ESSS PF10183.9 GAM18360.1 - 0.041 14.1 0.8 4.2 7.6 0.2 2.6 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Rxt3 PF08642.10 GAM18360.1 - 0.41 11.4 2.6 0.4 11.5 1.1 1.8 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 UPF0560 PF10577.9 GAM18360.1 - 3.5 6.0 6.5 4.7 5.6 6.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 BTB_2 PF02214.22 GAM18361.1 - 6.6e-23 80.9 0.3 2.5e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 GAM18361.1 - 1.2e-11 44.6 0.0 2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Fis1_TPR_C PF14853.6 GAM18361.1 - 5.9e-06 26.3 0.1 1.2e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 GAM18361.1 - 0.00013 21.5 0.5 0.0016 18.1 0.1 2.2 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.6 GAM18361.1 - 0.00015 22.2 0.0 0.00041 20.8 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM18361.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM18361.1 - 0.0012 19.0 0.1 0.0022 18.2 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GAM18361.1 - 0.0094 16.7 0.0 0.03 15.1 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM18361.1 - 0.016 15.3 0.2 0.033 14.3 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM18361.1 - 0.028 14.2 0.4 0.051 13.4 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM18361.1 - 0.046 14.4 0.0 0.14 12.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM18361.1 - 0.14 12.5 0.2 0.27 11.5 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Phosphoesterase PF04185.14 GAM18362.1 - 2.3e-91 306.7 1.9 3.1e-91 306.2 1.9 1.1 1 0 0 1 1 1 1 Phosphoesterase family CH PF00307.31 GAM18363.1 - 4.1e-15 55.9 0.2 2.3e-14 53.5 0.2 2.3 1 0 0 1 1 1 1 Calponin homology (CH) domain GAS2 PF02187.17 GAM18363.1 - 1e-10 41.5 0.0 7.8e-10 38.7 0.0 2.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Ribonucleas_3_3 PF14622.6 GAM18364.1 - 2.7e-19 69.6 0.0 4.6e-09 36.5 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 GAM18364.1 - 2e-15 57.3 0.8 2.3e-06 28.2 0.1 3.9 2 2 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.26 GAM18364.1 - 0.00099 19.8 0.0 0.0029 18.3 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif Chlorophyllase2 PF12740.7 GAM18364.1 - 0.11 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme XhlA PF10779.9 GAM18364.1 - 0.23 11.7 2.8 0.44 10.8 2.8 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Extensin_2 PF04554.13 GAM18364.1 - 6.1 7.0 61.3 0.4 10.8 36.7 2.5 1 1 1 2 2 2 0 Extensin-like region Methyltransf_16 PF10294.9 GAM18365.1 - 3.9e-20 72.3 4.2 4.1e-20 72.2 1.7 2.2 2 1 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 GAM18365.1 - 2.3e-05 24.0 0.2 3.9e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAM18365.1 - 0.0048 16.3 0.5 0.0089 15.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 GAM18365.1 - 0.012 16.3 0.1 0.024 15.4 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAM18365.1 - 0.014 16.1 0.1 0.042 14.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain GidB PF02527.15 GAM18365.1 - 0.019 14.3 0.2 0.041 13.2 0.2 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 GAM18365.1 - 0.028 14.2 0.3 0.087 12.6 0.3 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF2855 PF11017.8 GAM18365.1 - 0.055 13.2 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) NurA PF09376.10 GAM18365.1 - 0.075 12.7 0.2 0.099 12.3 0.2 1.6 1 1 0 1 1 1 0 NurA domain PCMT PF01135.19 GAM18365.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Spc7 PF08317.11 GAM18366.1 - 3.1e-05 23.0 9.6 3.1e-05 23.0 9.6 4.9 2 1 3 5 5 5 3 Spc7 kinetochore protein Golgin_A5 PF09787.9 GAM18366.1 - 7.4e-05 22.4 23.3 7.4e-05 22.4 23.3 4.2 2 1 2 4 4 4 3 Golgin subfamily A member 5 ATG16 PF08614.11 GAM18366.1 - 0.0087 16.3 14.9 0.0087 16.3 14.9 5.3 1 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Pre-PUA PF17832.1 GAM18366.1 - 2.8 8.7 6.0 5.4 7.8 1.3 3.4 2 1 0 2 2 2 0 Pre-PUA-like domain Patatin PF01734.22 GAM18367.1 - 4e-20 72.9 1.0 7.2e-20 72.0 1.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Transpos_assoc PF13963.6 GAM18368.1 - 0.16 12.3 0.0 1.2 9.5 0.0 2.3 3 0 0 3 3 3 0 Transposase-associated domain Med14 PF08638.11 GAM18369.1 - 3.2e-55 186.5 1.3 6.2e-55 185.6 0.1 2.2 2 0 0 2 2 2 1 Mediator complex subunit MED14 SUIM_assoc PF16619.5 GAM18369.1 - 0.0013 18.8 10.4 42 4.3 0.0 4.7 4 2 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 ABC2_membrane PF01061.24 GAM18370.1 - 8.8e-76 254.0 56.0 6.8e-41 140.0 18.7 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAM18370.1 - 1.6e-38 132.3 1.4 2.4e-25 89.7 0.0 4.0 3 1 1 4 4 3 3 ABC transporter AAA_21 PF13304.6 GAM18370.1 - 1.5e-07 31.5 0.0 0.15 11.9 0.0 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAM18370.1 - 1.9e-05 25.1 0.0 0.006 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM18370.1 - 2.4e-05 24.3 0.0 0.00077 19.4 0.0 2.6 3 0 0 3 3 2 1 RsgA GTPase AAA_18 PF13238.6 GAM18370.1 - 5.1e-05 23.8 1.4 0.02 15.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAM18370.1 - 0.00026 20.7 0.5 0.0061 16.3 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAM18370.1 - 0.00074 19.6 0.5 0.5 10.5 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GAM18370.1 - 0.0008 19.7 0.0 0.52 10.6 0.0 3.6 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 GAM18370.1 - 0.0062 15.8 0.0 0.2 10.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin CPT PF07931.12 GAM18370.1 - 0.014 15.2 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 GAM18370.1 - 0.02 15.1 0.0 0.77 10.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 GAM18370.1 - 0.025 14.8 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 GAM18370.1 - 0.027 14.0 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GAM18370.1 - 0.039 13.1 0.0 9.1 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF3292 PF11696.8 GAM18370.1 - 0.055 11.9 1.2 0.095 11.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) AAA_33 PF13671.6 GAM18370.1 - 0.15 12.2 0.0 0.6 10.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain Ploopntkinase3 PF18751.1 GAM18370.1 - 0.16 11.8 0.0 18 5.2 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Spt5_N PF11942.8 GAM18370.1 - 0.29 12.2 8.8 0.78 10.8 8.8 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2457 PF10446.9 GAM18370.1 - 6.1 5.9 8.7 11 5.0 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FNIP PF05725.12 GAM18371.1 - 9.7e-20 70.5 15.0 1.2e-10 41.4 0.9 3.8 5 0 0 5 5 5 2 FNIP Repeat DNA_pol_B_2 PF03175.13 GAM18373.1 - 5e-05 22.4 0.0 6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral FNIP PF05725.12 GAM18375.1 - 3.9e-51 171.0 28.3 3.3e-12 46.4 0.5 8.1 3 2 4 9 9 9 8 FNIP Repeat LRR_5 PF13306.6 GAM18375.1 - 0.003 17.5 1.9 0.024 14.6 0.1 3.0 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 GAM18376.1 - 6.8e-47 157.4 13.5 6.8e-15 55.0 0.0 7.5 6 2 2 9 9 9 6 FNIP Repeat LRR_5 PF13306.6 GAM18376.1 - 0.13 12.2 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) JAKMIP_CC3 PF16034.5 GAM18377.1 - 0.0056 16.7 8.8 0.0083 16.1 8.8 1.3 1 0 0 1 1 1 1 JAKMIP CC3 domain PSY3 PF16836.5 GAM18377.1 - 0.032 13.7 1.5 0.044 13.3 1.5 1.1 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description PikAIV_N PF18605.1 GAM18377.1 - 0.1 12.2 0.6 0.28 10.8 0.6 1.7 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Kelch_6 PF13964.6 GAM18378.1 - 2.3e-11 43.5 9.2 1.7e-05 25.0 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 GAM18378.1 - 1.1e-08 34.6 1.5 0.00078 19.0 0.0 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM18378.1 - 4.1e-08 33.1 5.0 0.011 15.7 0.1 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain zf-B_box PF00643.24 GAM18378.1 - 2.9e-07 30.5 10.3 5.5e-07 29.6 10.3 1.5 1 0 0 1 1 1 1 B-box zinc finger Kelch_3 PF13415.6 GAM18378.1 - 3.6e-06 27.1 3.6 0.13 12.6 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM18378.1 - 0.00026 20.8 7.7 0.24 11.4 0.1 5.0 5 1 0 5 5 5 2 Kelch motif Spc29 PF17082.5 GAM18378.1 - 0.00054 19.9 0.6 0.067 13.0 0.6 2.6 2 1 0 2 2 2 1 Spindle Pole Component 29 Baculo_PEP_C PF04513.12 GAM18378.1 - 0.0017 18.4 2.8 0.0034 17.4 2.8 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_5 PF13854.6 GAM18378.1 - 0.0037 17.2 5.2 0.59 10.2 0.1 3.6 3 0 0 3 3 3 1 Kelch motif zf-nanos PF05741.13 GAM18378.1 - 0.069 13.4 3.7 0.14 12.4 3.7 1.5 1 0 0 1 1 1 0 Nanos RNA binding domain Kelch_6 PF13964.6 GAM18379.1 - 8.2e-14 51.3 8.3 3.4e-05 24.0 0.0 5.2 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM18379.1 - 8.3e-12 44.9 3.7 0.004 17.1 0.0 5.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM18379.1 - 5e-09 35.6 1.8 0.012 15.2 0.0 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 GAM18379.1 - 3.2e-06 27.3 0.8 3.5 8.0 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM18379.1 - 7.2e-05 22.7 1.4 0.5 10.4 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAM18379.1 - 0.00015 21.6 5.8 0.27 11.3 0.1 4.7 6 0 0 6 6 6 2 Kelch motif Spc29 PF17082.5 GAM18379.1 - 0.015 15.2 2.6 0.026 14.4 2.6 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Baculo_PEP_C PF04513.12 GAM18379.1 - 0.066 13.3 2.1 0.17 11.9 2.1 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_6 PF13964.6 GAM18380.1 - 8.6e-14 51.2 3.9 8.9e-07 29.0 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 GAM18380.1 - 4.5e-10 39.0 0.3 0.00016 21.2 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM18380.1 - 3.1e-09 36.7 2.6 0.0081 16.1 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM18380.1 - 2.3e-08 33.7 0.5 0.051 13.6 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 GAM18380.1 - 4.7e-08 33.1 0.5 0.43 10.9 0.0 4.6 5 0 0 5 5 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM18380.1 - 3.7e-05 23.6 2.6 0.18 11.8 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Baculo_PEP_C PF04513.12 GAM18380.1 - 0.0052 16.8 0.6 0.01 15.9 0.6 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus PA28_beta PF02252.18 GAM18380.1 - 0.041 13.5 0.2 0.093 12.4 0.2 1.6 1 1 0 1 1 1 0 Proteasome activator pa28 beta subunit DUF4618 PF15397.6 GAM18380.1 - 0.042 13.3 0.7 0.11 11.9 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) RPW8 PF05659.11 GAM18380.1 - 0.11 12.1 1.3 0.96 9.1 0.5 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PHTB1_C PF14728.6 GAM18380.1 - 0.15 11.1 1.0 0.23 10.5 1.0 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus Fib_alpha PF08702.10 GAM18380.1 - 0.27 11.4 1.5 0.92 9.7 1.1 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 GAM18380.1 - 0.62 10.6 2.9 8.7 6.9 1.1 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TnpB_IS66 PF05717.13 GAM18381.1 - 0.023 14.6 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 IS66 Orf2 like protein Pescadillo_N PF06732.11 GAM18382.1 - 9.3e-107 356.6 7.1 9.3e-107 356.6 7.1 2.1 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 GAM18382.1 - 4.1e-12 46.3 0.0 1.4e-11 44.6 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAM18382.1 - 1.3e-05 25.5 0.0 5.3e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 GAM18382.1 - 0.0009 19.5 0.0 0.0009 19.5 0.0 2.6 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain DUF3439 PF11921.8 GAM18382.1 - 4.8 7.2 23.5 2.1 8.3 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HIT PF01230.23 GAM18383.1 - 1.6e-23 83.3 0.0 5.2e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 GAM18383.1 - 7.7e-17 61.8 0.0 4.4e-16 59.4 0.0 1.9 1 1 1 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Ribosomal_S17 PF00366.20 GAM18383.1 - 0.14 12.3 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S17 WI12 PF07107.11 GAM18383.1 - 0.16 12.1 0.1 0.39 10.9 0.0 1.6 2 0 0 2 2 2 0 Wound-induced protein WI12 Big_2 PF02368.18 GAM18383.1 - 0.22 11.5 1.5 1.4 8.9 1.3 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Tim17 PF02466.19 GAM18384.1 - 8.2e-10 39.0 2.2 8.2e-10 39.0 2.2 1.7 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF2189 PF09955.9 GAM18384.1 - 0.028 14.7 2.1 7.4 6.8 0.7 2.8 1 1 2 3 3 3 0 Predicted integral membrane protein (DUF2189) TMEM135_C_rich PF15982.5 GAM18384.1 - 0.031 14.9 1.2 0.038 14.6 0.3 1.5 2 0 0 2 2 2 0 N-terminal cysteine-rich region of Transmembrane protein 135 CRA PF06589.11 GAM18384.1 - 0.084 13.0 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Presenilin PF01080.17 GAM18384.1 - 0.11 11.2 0.5 0.17 10.6 0.5 1.4 1 0 0 1 1 1 0 Presenilin Yippee-Mis18 PF03226.14 GAM18385.1 - 1.2e-17 64.0 0.3 3e-17 62.7 0.3 1.7 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3439 PF11921.8 GAM18385.1 - 0.032 14.2 3.8 0.065 13.2 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) adh_short PF00106.25 GAM18387.1 - 2.5e-48 164.1 0.3 3.3e-48 163.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM18387.1 - 9.7e-35 120.2 0.1 1.3e-34 119.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM18387.1 - 2.7e-12 47.0 0.2 3.8e-12 46.5 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM18387.1 - 0.00014 21.4 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 GAM18387.1 - 0.0069 16.3 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAM18387.1 - 0.023 13.8 0.1 0.034 13.3 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 GAM18388.1 - 4.4e-49 166.6 0.0 5.5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM18388.1 - 8.1e-36 123.7 0.0 9.9e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM18388.1 - 4e-11 43.2 0.0 5.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM18388.1 - 1.2e-05 24.8 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 GAM18388.1 - 5.5e-05 23.1 0.0 7.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAM18388.1 - 0.00015 21.0 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 GAM18388.1 - 0.0045 16.5 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM18388.1 - 0.16 11.3 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Erf4 PF10256.9 GAM18389.1 - 0.052 13.7 1.6 0.11 12.6 1.6 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Ac76 PF05814.11 GAM18389.1 - 0.053 13.5 3.9 0.15 12.1 3.6 1.8 1 1 0 1 1 1 0 Orf76 (Ac76) Herpes_LMP1 PF05297.11 GAM18389.1 - 0.055 12.7 0.6 0.065 12.4 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3149 PF11346.8 GAM18389.1 - 1.2 8.8 6.3 0.16 11.6 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) EMP70 PF02990.16 GAM18390.1 - 3.6e-24 85.3 28.4 4e-21 75.3 11.8 2.4 2 1 1 3 3 3 2 Endomembrane protein 70 DUF3394 PF11874.8 GAM18390.1 - 0.36 10.5 1.3 0.46 10.1 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) SR-25 PF10500.9 GAM18391.1 - 7.2e-11 42.1 0.5 9.2e-11 41.8 0.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein EF-hand_4 PF12763.7 GAM18392.1 - 2.7e-14 53.0 0.0 7.2e-14 51.6 0.0 1.6 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 GAM18392.1 - 8.1e-05 21.9 0.1 0.00017 20.9 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 GAM18392.1 - 0.0018 18.1 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 GAM18392.1 - 0.0064 15.9 0.1 0.015 14.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 GAM18392.1 - 0.066 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 GAM18392.1 - 0.12 12.2 0.1 0.46 10.4 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM18392.1 - 0.21 11.9 1.3 0.72 10.2 0.5 2.1 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ribosomal_L24 PF17136.4 GAM18393.1 - 7.4e-14 51.9 0.2 1.6e-13 50.8 0.2 1.6 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 GAM18393.1 - 3.1e-10 39.6 0.2 1.4e-09 37.5 0.3 2.0 2 0 0 2 2 2 1 KOW motif LSM14 PF12701.7 GAM18393.1 - 0.019 15.1 0.0 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 Scd6-like Sm domain Ribosomal_L28e PF01778.17 GAM18394.1 - 2.8e-35 121.5 0.4 2.8e-35 121.5 0.4 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 GAM18394.1 - 6.2e-20 71.7 30.5 1.8e-18 67.0 30.5 2.5 1 1 0 1 1 1 1 Mak16 protein C-terminal region BUD22 PF09073.10 GAM18394.1 - 0.002 17.6 15.5 0.0025 17.3 15.5 1.1 1 0 0 1 1 1 1 BUD22 DUF2722 PF10846.8 GAM18394.1 - 5.9 5.7 12.3 9.5 5.0 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Zn_clus PF00172.18 GAM18395.1 - 7e-06 26.1 7.9 1.5e-05 25.0 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauE PF01925.19 GAM18396.1 - 2.5e-24 86.3 23.9 8.5e-22 77.9 23.9 2.2 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE Josephin PF02099.17 GAM18397.1 - 1.7e-09 38.0 0.1 2e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Josephin ABC_tran PF00005.27 GAM18398.1 - 5.7e-28 98.1 0.1 1.1e-27 97.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GAM18398.1 - 3.1e-27 95.4 30.9 5.4e-27 94.6 30.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_25 PF13481.6 GAM18398.1 - 8.4e-06 25.5 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM18398.1 - 2.8e-05 24.6 0.0 5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 GAM18398.1 - 3.5e-05 23.8 0.0 0.084 12.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAM18398.1 - 3.8e-05 23.7 0.2 0.00037 20.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 GAM18398.1 - 0.00032 21.1 0.0 0.0022 18.4 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM18398.1 - 0.00091 19.5 0.2 0.0055 17.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 GAM18398.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 GAM18398.1 - 0.002 17.6 0.1 0.0036 16.8 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 GAM18398.1 - 0.015 15.6 0.2 0.03 14.6 0.2 1.5 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.12 GAM18398.1 - 0.021 14.7 0.1 0.021 14.7 0.1 2.8 3 1 0 3 3 2 0 CDR ABC transporter AAA_18 PF13238.6 GAM18398.1 - 0.021 15.3 0.0 0.045 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAM18398.1 - 0.024 14.6 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 GAM18398.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 GAM18398.1 - 0.038 13.7 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 GAM18398.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 GAM18398.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 GAM18398.1 - 0.066 13.7 0.2 0.1 13.1 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM18398.1 - 0.076 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAM18398.1 - 0.077 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 GAM18398.1 - 0.077 13.0 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 GAM18398.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_35 PF14516.6 GAM18398.1 - 0.081 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain IstB_IS21 PF01695.17 GAM18398.1 - 0.086 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 GAM18398.1 - 0.09 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 GAM18398.1 - 0.12 11.0 0.2 0.71 8.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF423 PF04241.15 GAM18398.1 - 2.8 8.2 6.0 21 5.4 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF423) Flu_C_NS1 PF03506.13 GAM18399.1 - 0.16 12.0 0.6 0.3 11.1 0.6 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) CAP PF00188.26 GAM18400.1 - 5.8e-06 27.2 0.1 1.6e-05 25.7 0.1 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family RNA_polI_A34 PF08208.11 GAM18400.1 - 0.44 10.6 22.9 0.66 10.0 22.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SR-25 PF10500.9 GAM18400.1 - 0.66 9.6 18.2 0.94 9.0 18.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 GAM18400.1 - 0.99 9.2 11.5 1.4 8.6 11.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 GAM18400.1 - 1.9 8.8 18.0 2.7 8.3 18.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 GAM18400.1 - 2.5 6.3 14.0 3.5 5.8 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 GAM18400.1 - 2.7 7.4 11.1 3.8 6.9 11.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 GAM18400.1 - 4.6 6.9 8.1 17 5.1 8.8 1.6 2 0 0 2 2 2 0 Connexin Zip PF02535.22 GAM18400.1 - 8.7 5.4 7.1 11 5.1 7.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 GAM18400.1 - 9 6.5 9.7 14 5.8 9.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DEAD PF00270.29 GAM18401.1 - 1.2e-47 161.9 0.0 2.8e-47 160.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM18401.1 - 6.7e-30 103.7 0.0 3e-28 98.4 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAM18401.1 - 0.11 12.8 0.6 0.45 10.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain TMEM51 PF15345.6 GAM18401.1 - 4.1 7.2 10.4 0.13 12.1 0.9 2.5 2 0 0 2 2 2 0 Transmembrane protein 51 VWA PF00092.28 GAM18402.1 - 1.2e-06 28.9 0.1 7.1e-06 26.4 0.1 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM18402.1 - 0.0063 17.1 0.4 0.068 13.8 0.0 2.8 2 2 0 2 2 2 1 von Willebrand factor type A domain CPBP PF02517.16 GAM18404.1 - 0.00045 20.5 16.6 0.00045 20.5 16.6 2.5 3 0 0 3 3 3 1 CPBP intramembrane metalloprotease Ribosomal_L7Ae PF01248.26 GAM18405.1 - 0.022 14.5 0.0 0.065 13.0 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AAA_11 PF13086.6 GAM18405.1 - 0.21 11.3 11.7 0.37 10.5 8.6 2.0 1 1 1 2 2 2 0 AAA domain EMC3_TMCO1 PF01956.16 GAM18405.1 - 1.4 8.6 7.7 1.6 8.5 6.7 1.6 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DEAD PF00270.29 GAM18406.1 - 3.1e-34 118.3 0.8 1e-33 116.6 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM18406.1 - 1.8e-28 99.1 0.0 3.8e-27 94.8 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM18406.1 - 9.4e-10 38.7 0.0 3.9e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 GAM18406.1 - 0.02 14.4 0.0 0.45 10.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Ank_4 PF13637.6 GAM18406.1 - 0.031 14.9 0.1 17 6.1 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeats (many copies) RNF220 PF15926.5 GAM18407.1 - 9.3e-20 71.3 19.6 9.3e-20 71.3 19.6 3.5 1 1 1 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 GAM18407.1 - 1.8e-10 40.5 14.3 1.8e-10 40.5 14.3 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM18407.1 - 0.00086 19.1 17.7 0.013 15.4 11.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM18407.1 - 0.0024 17.7 8.8 0.0024 17.7 8.8 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) AT_hook PF02178.19 GAM18407.1 - 0.011 15.5 20.0 0.071 13.0 4.2 2.6 2 0 0 2 2 2 0 AT hook motif Prok-RING_4 PF14447.6 GAM18407.1 - 0.027 14.3 13.5 0.33 10.9 7.8 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAM18407.1 - 1.8 8.6 10.7 1.7 8.8 7.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAM18407.1 - 2.1 8.3 19.0 0.22 11.5 11.0 2.9 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM18407.1 - 2.4 8.3 13.5 0.16 12.0 8.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger Histone PF00125.24 GAM18408.1 - 2.7e-49 166.9 0.4 3e-49 166.7 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAM18408.1 - 2.6e-05 24.3 0.1 4.5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAM18408.1 - 5.9e-05 23.4 0.0 9.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 GAM18408.1 - 0.094 13.3 0.2 0.13 12.9 0.2 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain IKI3 PF04762.12 GAM18409.1 - 1.5e-253 844.0 0.0 8.9e-253 841.4 0.0 2.0 2 0 0 2 2 2 1 IKI3 family ANAPC4_WD40 PF12894.7 GAM18409.1 - 4.9e-05 23.5 0.0 1.2 9.5 0.0 4.6 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Dicty_REP PF05086.12 GAM18409.1 - 0.25 9.3 6.8 0.44 8.5 6.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UCH PF00443.29 GAM18410.1 - 1.2e-74 251.0 1.2 1.2e-74 251.0 1.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAM18410.1 - 2.8e-15 56.7 0.9 2.8e-15 56.7 0.9 2.9 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 GAM18410.1 - 5.7e-13 49.1 1.5 4.9e-06 26.3 0.1 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_3 PF14836.6 GAM18410.1 - 1.5e-08 34.5 0.0 3.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain USP7_C2 PF14533.6 GAM18410.1 - 6e-06 26.1 1.4 0.02 14.6 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal SNARE PF05739.19 GAM18412.1 - 4.8e-05 23.3 3.9 0.00014 21.8 1.5 2.3 2 0 0 2 2 2 1 SNARE domain ABC2_membrane_3 PF12698.7 GAM18412.1 - 0.0051 16.0 3.3 0.0068 15.6 3.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF2207 PF09972.9 GAM18412.1 - 0.015 14.1 1.5 0.023 13.5 1.5 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Use1 PF09753.9 GAM18412.1 - 0.025 14.3 6.4 0.033 13.9 6.4 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF2206 PF09971.9 GAM18412.1 - 0.35 9.6 4.7 0.25 10.1 2.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) TMPIT PF07851.13 GAM18412.1 - 9 5.4 8.1 2 7.6 1.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein tRNA-synt_2b PF00587.25 GAM18413.1 - 2.1e-36 125.6 0.0 3.4e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAM18413.1 - 9.7e-16 58.0 3.6 9.7e-16 58.0 3.6 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Uds1 PF15456.6 GAM18413.1 - 0.056 13.6 1.5 0.13 12.4 1.5 1.5 1 0 0 1 1 1 0 Up-regulated During Septation DUF211 PF02680.14 GAM18413.1 - 0.14 12.3 0.2 0.28 11.4 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 DUF4407 PF14362.6 GAM18413.1 - 0.32 10.3 1.9 0.5 9.7 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 GAM18413.1 - 0.53 10.8 4.5 0.17 12.4 0.9 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region PI3K_P85_iSH2 PF16454.5 GAM18413.1 - 0.85 9.2 7.5 0.4 10.2 0.4 2.8 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DivIC PF04977.15 GAM18413.1 - 9.7 6.0 6.5 1.2 9.0 0.6 2.4 3 0 0 3 3 3 0 Septum formation initiator DNA_pol_B_2 PF03175.13 GAM18415.1 - 0.021 13.7 0.2 0.03 13.2 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DARPP-32 PF05395.12 GAM18417.1 - 0.072 13.3 2.4 2 8.6 0.2 2.2 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 KIF1B PF12423.8 GAM18417.1 - 0.093 13.2 1.8 0.21 12.1 1.8 1.6 1 0 0 1 1 1 0 Kinesin protein 1B Gelsolin PF00626.22 GAM18418.1 - 1.9e-33 114.2 0.0 1e-07 31.8 0.0 5.8 5 0 0 5 5 5 5 Gelsolin repeat PBD PF00786.28 GAM18418.1 - 1.3e-06 28.7 0.1 1.3e-06 28.7 0.1 3.3 4 0 0 4 4 4 1 P21-Rho-binding domain WASH-7_N PF14745.6 GAM18419.1 - 8.1e-193 642.0 3.4 1.2e-192 641.4 3.4 1.3 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.6 GAM18419.1 - 5.7e-151 502.5 6.5 1.4e-150 501.2 6.5 1.7 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.6 GAM18419.1 - 1.2e-61 207.4 5.2 2.7e-61 206.3 5.2 1.7 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal Peptidase_M28 PF04389.17 GAM18422.1 - 8.3e-21 74.6 0.0 3.7e-20 72.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 GAM18422.1 - 4.8e-05 22.9 0.0 0.0024 17.4 0.0 2.1 2 0 0 2 2 2 2 Nicastrin Peptidase_M20 PF01546.28 GAM18422.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 EF1_GNE PF00736.19 GAM18423.1 - 4.2e-34 116.6 0.5 8.2e-34 115.7 0.5 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_6 PF17171.4 GAM18423.1 - 0.002 17.9 0.0 0.005 16.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM18423.1 - 0.006 16.8 0.3 0.013 15.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM18423.1 - 0.0088 16.2 0.7 0.046 13.9 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain EF-1_beta_acid PF10587.9 GAM18423.1 - 0.03 14.8 6.7 0.075 13.5 6.7 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 GAM18423.1 - 0.044 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tnp_22_trimer PF17489.2 GAM18423.1 - 0.12 12.4 0.3 1.6 8.7 0.0 2.5 3 0 0 3 3 3 0 L1 transposable element trimerization domain DUF3932 PF13068.6 GAM18424.1 - 0.098 12.9 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) MyTH4 PF00784.17 GAM18424.1 - 0.15 12.6 0.1 0.26 11.8 0.1 1.3 1 0 0 1 1 1 0 MyTH4 domain DUF3719 PF12516.8 GAM18425.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Acyltransferase PF01553.21 GAM18426.1 - 4e-12 45.9 0.0 7.9e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase LRR_6 PF13516.6 GAM18427.1 - 1.1e-12 46.9 30.4 0.019 15.0 0.1 10.6 12 0 0 12 12 12 5 Leucine Rich repeat LRR_8 PF13855.6 GAM18427.1 - 2.6e-06 27.1 36.2 0.0037 17.0 0.3 9.1 6 4 2 8 8 8 3 Leucine rich repeat LRR_4 PF12799.7 GAM18427.1 - 1.3e-05 25.5 35.0 0.41 11.1 1.5 8.5 8 2 2 10 10 10 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM18427.1 - 3.6e-05 23.7 23.6 1.8 9.4 0.0 9.9 11 0 0 11 11 11 2 Leucine Rich Repeat Ras PF00071.22 GAM18428.1 - 1.4e-44 151.6 0.8 1.6e-44 151.4 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM18428.1 - 2.8e-15 56.6 0.1 4.8e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM18428.1 - 1.3e-08 34.5 0.1 1.6e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM18428.1 - 4.4e-06 26.4 0.5 2.9e-05 23.7 0.1 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM18428.1 - 0.00013 21.9 0.2 0.0023 17.8 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAM18428.1 - 0.0013 18.8 0.2 0.0021 18.1 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 GAM18428.1 - 0.0024 17.9 0.1 0.0042 17.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM18428.1 - 0.087 13.1 0.1 2.1 8.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain Tetraspanin PF00335.20 GAM18429.1 - 0.00036 20.3 18.7 0.00036 20.3 18.7 1.9 1 1 2 3 3 3 1 Tetraspanin family TssN PF17555.2 GAM18429.1 - 1.1 8.6 16.3 2 7.8 16.0 1.6 1 1 0 1 1 1 0 Type VI secretion system, TssN YfhO PF09586.10 GAM18429.1 - 1.1 7.4 7.8 1.3 7.1 7.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Clostridium_P47 PF06597.11 GAM18429.1 - 1.1 7.9 3.3 1.5 7.4 3.3 1.1 1 0 0 1 1 1 0 Clostridium P-47 protein Yip1 PF04893.17 GAM18429.1 - 4.5 6.9 23.8 14 5.4 23.8 1.8 1 1 0 1 1 1 0 Yip1 domain YwiC PF14256.6 GAM18429.1 - 5.3 7.4 13.6 37 4.7 10.2 2.2 2 1 0 2 2 2 0 YwiC-like protein CoA_binding_3 PF13727.6 GAM18429.1 - 7.6 6.5 11.2 1.2 9.2 6.5 1.9 2 1 1 3 3 3 0 CoA-binding domain DUF2070 PF09843.9 GAM18429.1 - 7.8 4.7 10.8 9 4.5 10.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Chlam_PMP PF02415.17 GAM18430.1 - 0.31 11.6 20.9 13 6.5 2.8 7.6 6 1 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ephrin_rec_like PF07699.13 GAM18430.1 - 8.1 6.3 11.5 15 5.4 4.5 2.8 2 0 0 2 2 2 0 Putative ephrin-receptor like PHD PF00628.29 GAM18431.1 - 3.3e-06 26.9 7.1 3.3e-06 26.9 7.1 3.8 3 1 0 3 3 3 1 PHD-finger L31 PF09784.9 GAM18431.1 - 0.012 16.0 0.1 0.029 14.8 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 MRP-L28 PF09812.9 GAM18431.1 - 0.016 15.3 2.0 0.016 15.3 2.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 DUF5582 PF17819.1 GAM18431.1 - 0.6 10.6 11.5 0.56 10.7 3.1 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5582) FAM176 PF14851.6 GAM18431.1 - 0.78 9.4 8.2 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 FAM176 family DUF334 PF03904.13 GAM18431.1 - 3.4 7.1 6.3 7.7 6.0 6.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF334) FSA_C PF10479.9 GAM18431.1 - 4.5 5.3 13.7 3.6 5.6 4.5 2.1 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus SF3b1 PF08920.10 GAM18432.1 - 2.5e-32 111.9 0.5 2.5e-32 111.9 0.5 3.0 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT PF02985.22 GAM18432.1 - 1.6e-12 46.5 2.1 0.058 13.7 0.0 8.2 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 GAM18432.1 - 6e-10 39.4 7.0 2.2 8.7 0.0 7.9 4 2 5 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 GAM18432.1 - 3.8e-08 33.6 0.2 4.9 7.8 0.0 6.6 7 0 0 7 7 6 2 HEAT-like repeat Cnd1 PF12717.7 GAM18432.1 - 4e-08 33.5 5.0 0.2 11.7 0.0 6.1 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 GAM18432.1 - 1.1e-07 31.3 0.1 0.0016 17.6 0.1 3.5 3 0 0 3 3 3 2 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 GAM18432.1 - 7.3e-05 22.7 5.0 0.49 10.3 0.0 5.7 3 1 2 6 6 6 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 GAM18432.1 - 7.5e-05 23.3 4.2 2.5 8.7 0.0 5.2 6 0 0 6 6 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 GAM18432.1 - 0.00092 18.8 0.6 1.4 8.5 0.0 3.6 3 1 0 3 3 3 1 CLASP N terminal NUC173 PF08161.12 GAM18432.1 - 0.0065 16.1 1.9 16 5.1 0.0 5.4 3 2 2 5 5 5 0 NUC173 domain DUF3708 PF12501.8 GAM18432.1 - 0.015 15.1 1.0 0.041 13.7 0.4 2.1 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter RTP1_C1 PF10363.9 GAM18432.1 - 0.017 15.3 2.7 1.1 9.5 0.1 3.8 4 2 1 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DRIM PF07539.12 GAM18432.1 - 0.031 12.6 0.1 3.2 6.0 0.0 3.2 2 1 1 3 3 3 0 Down-regulated in metastasis TAF6_C PF07571.13 GAM18432.1 - 0.045 14.1 0.0 0.45 10.9 0.0 2.8 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain ParcG PF10274.9 GAM18432.1 - 0.058 13.5 4.6 14 5.7 0.0 4.6 3 1 3 6 6 6 0 Parkin co-regulated protein RuvB_C PF05491.13 GAM18432.1 - 0.17 11.8 0.2 3.6 7.5 0.0 3.2 3 0 0 3 3 2 0 RuvB C-terminal winged helix domain Ret2_MD PF18528.1 GAM18432.1 - 0.57 10.6 2.4 3.2 8.2 0.1 2.9 3 0 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain DUF4690 PF15756.5 GAM18433.1 - 0.099 13.3 2.4 0.32 11.6 2.4 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Metallophos PF00149.28 GAM18434.1 - 7.6e-39 134.3 0.1 9.8e-39 134.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAM18434.1 - 5.3e-05 23.6 0.7 0.00014 22.3 0.7 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 GAM18434.1 - 0.038 14.2 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ku PF02735.16 GAM18435.1 - 2.3e-42 145.0 0.4 4.9e-42 144.0 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 GAM18435.1 - 2.5e-36 124.4 0.3 7.5e-36 122.9 0.1 2.0 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 GAM18435.1 - 6.2e-27 94.8 4.3 1.1e-26 93.9 4.3 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 GAM18435.1 - 7.5e-09 36.2 3.9 1.4e-08 35.3 0.1 3.2 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 GAM18435.1 - 0.0008 19.7 1.1 0.0008 19.7 1.1 2.2 3 0 0 3 3 3 1 von Willebrand factor type A domain SBP_bac_5 PF00496.22 GAM18435.1 - 0.0047 15.9 0.6 0.017 14.1 0.2 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle MGS PF02142.22 GAM18435.1 - 0.022 14.9 0.1 0.062 13.5 0.1 1.8 1 0 0 1 1 1 0 MGS-like domain SPOC PF07744.13 GAM18435.1 - 0.032 14.1 0.1 0.48 10.3 0.0 2.5 2 0 0 2 2 2 0 SPOC domain Herpes_HEPA PF03324.14 GAM18435.1 - 0.18 12.3 0.3 18 5.9 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus DNA helicase/primase complex associated protein Histone PF00125.24 GAM18437.1 - 2.7e-49 166.9 0.4 3e-49 166.7 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAM18437.1 - 2.6e-05 24.3 0.1 4.5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAM18437.1 - 5.9e-05 23.4 0.0 9.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 GAM18437.1 - 0.094 13.3 0.2 0.13 12.9 0.2 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Myotub-related PF06602.14 GAM18438.1 - 9.9e-82 274.7 3.0 1.4e-80 270.9 0.0 2.3 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain COR PF16095.5 GAM18438.1 - 6.8e-55 185.9 0.1 1.3e-54 185.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Pkinase_Tyr PF07714.17 GAM18438.1 - 4.2e-51 173.7 0.0 1e-50 172.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM18438.1 - 1.8e-39 135.7 0.0 3.6e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 GAM18438.1 - 2.1e-27 94.7 45.4 1.3e-07 31.3 6.4 6.2 3 1 0 5 5 5 5 Leucine rich repeat Roc PF08477.13 GAM18438.1 - 3.8e-24 85.2 0.0 9.9e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_4 PF12799.7 GAM18438.1 - 1.3e-22 79.5 54.2 1.4e-06 28.5 0.5 7.9 5 2 2 7 7 7 6 Leucine Rich repeats (2 copies) Ras PF00071.22 GAM18438.1 - 5.5e-13 48.8 0.1 1.6e-12 47.3 0.1 1.8 1 1 0 1 1 1 1 Ras family WD40 PF00400.32 GAM18438.1 - 1.7e-08 35.0 23.3 0.0015 19.3 0.8 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Arf PF00025.21 GAM18438.1 - 0.00052 19.5 0.8 0.003 17.0 0.8 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family WD40_like PF17005.5 GAM18438.1 - 0.0019 17.6 6.2 0.0055 16.1 0.5 3.5 3 1 0 3 3 3 1 WD40-like domain MMR_HSR1 PF01926.23 GAM18438.1 - 0.0031 17.6 0.0 0.0091 16.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 GAM18438.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 GAM18438.1 - 0.035 14.4 0.0 28 5.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain RGS PF00615.19 GAM18439.1 - 2.4e-20 72.9 1.3 1.8e-13 50.8 0.6 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain PRANC PF09372.10 GAM18439.1 - 0.092 13.1 1.4 0.46 10.8 0.3 2.4 2 0 0 2 2 2 0 PRANC domain Xpo1 PF08389.12 GAM18440.1 - 2.9e-15 56.6 5.4 6e-14 52.3 0.3 4.1 3 0 0 3 3 3 1 Exportin 1-like protein Importin_rep_3 PF18806.1 GAM18440.1 - 1.3e-06 28.3 0.0 3.5e-05 23.7 0.0 3.1 3 0 0 3 3 3 1 Importin 13 repeat IBN_N PF03810.19 GAM18440.1 - 2e-05 24.4 1.6 0.00015 21.6 1.6 2.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain DNA_alkylation PF08713.11 GAM18440.1 - 0.025 14.3 0.1 0.1 12.3 0.1 2.0 2 0 0 2 2 2 0 DNA alkylation repair enzyme RasGEF_N PF00618.20 GAM18440.1 - 0.049 13.9 3.9 0.089 13.0 1.3 2.8 3 0 0 3 3 3 0 RasGEF N-terminal motif Gal4_dimer PF03902.13 GAM18440.1 - 0.45 10.7 2.0 1.7 8.9 0.0 2.9 3 0 0 3 3 3 0 Gal4-like dimerisation domain Apis_Csd PF11671.8 GAM18440.1 - 3.7 7.5 8.9 11 6.0 8.9 1.8 1 0 0 1 1 1 0 Complementary sex determiner protein ACP_PD PF04336.12 GAM18441.1 - 0.08 13.4 0.5 0.57 10.6 0.1 2.3 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase DUF3774 PF12609.8 GAM18441.1 - 0.099 13.7 1.4 0.22 12.6 0.1 2.3 3 0 0 3 3 3 0 Wound-induced protein Abi_C PF14355.6 GAM18441.1 - 0.13 12.4 0.0 0.99 9.6 0.0 2.6 2 0 0 2 2 2 0 Abortive infection C-terminus Staph_haemo PF05480.11 GAM18441.1 - 0.16 11.7 0.6 0.87 9.4 0.0 2.6 3 0 0 3 3 3 0 Staphylococcus haemolytic protein REF PF05755.12 GAM18441.1 - 0.18 11.6 2.9 0.51 10.1 0.1 2.6 2 1 1 3 3 3 0 Rubber elongation factor protein (REF) PriC PF07445.12 GAM18441.1 - 1.4 8.8 6.4 0.81 9.6 2.7 2.3 1 1 0 2 2 2 0 Primosomal replication protein priC RBFA PF02033.18 GAM18442.1 - 4.4e-07 30.3 0.3 0.00036 21.0 0.2 2.8 2 0 0 2 2 2 2 Ribosome-binding factor A SUIM_assoc PF16619.5 GAM18442.1 - 0.23 11.6 10.2 1.4 9.1 10.2 2.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ras PF00071.22 GAM18445.1 - 4.1e-51 172.8 0.0 4.7e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM18445.1 - 3.7e-32 111.1 0.0 5e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM18445.1 - 2.6e-16 59.5 0.0 3.2e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM18445.1 - 4.9e-08 32.6 0.0 6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM18445.1 - 4.9e-06 26.2 0.1 0.00022 20.9 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM18445.1 - 0.00037 20.6 0.0 0.0006 19.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAM18445.1 - 0.00095 18.6 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 GAM18445.1 - 0.0054 16.5 0.1 0.92 9.2 0.0 2.3 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation DLIC PF05783.11 GAM18445.1 - 0.058 12.2 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 GAM18445.1 - 0.065 13.1 0.1 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 GAM18445.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 Dynamin family DUF4407 PF14362.6 GAM18446.1 - 0.0022 17.4 14.1 0.0022 17.4 14.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) BshC PF10079.9 GAM18446.1 - 0.013 14.3 8.4 0.016 13.9 8.4 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC ABC_tran_CTD PF16326.5 GAM18446.1 - 0.014 15.6 8.1 0.67 10.2 0.2 2.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF2730 PF10805.8 GAM18446.1 - 0.023 14.8 1.1 0.037 14.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF5082 PF16888.5 GAM18446.1 - 0.029 14.6 16.1 0.45 10.8 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) PIN_8 PF18476.1 GAM18446.1 - 0.03 14.2 4.2 0.036 13.9 4.2 1.1 1 0 0 1 1 1 0 PIN like domain HMMR_N PF15905.5 GAM18446.1 - 0.032 13.7 9.5 0.047 13.2 9.5 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Not3 PF04065.15 GAM18446.1 - 0.049 13.0 8.5 0.065 12.7 8.5 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component GTP-bdg_M PF16360.5 GAM18446.1 - 0.05 14.2 4.5 0.13 12.9 4.5 1.7 1 1 0 1 1 1 0 GTP-binding GTPase Middle Region Filament PF00038.21 GAM18446.1 - 0.12 11.9 14.2 0.16 11.5 14.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein Baculo_PEP_C PF04513.12 GAM18446.1 - 0.13 12.3 11.8 0.17 11.9 11.8 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 GAM18446.1 - 0.15 12.5 3.4 6 7.3 0.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) COOH-NH2_lig PF14395.6 GAM18446.1 - 0.23 10.7 4.0 0.33 10.1 2.7 1.7 1 1 1 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 DUF87 PF01935.17 GAM18446.1 - 0.24 11.5 1.9 0.29 11.2 1.9 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain DUF4200 PF13863.6 GAM18446.1 - 0.27 11.6 13.5 1.2 9.5 1.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.11 GAM18446.1 - 0.3 11.7 7.3 2.5 8.7 7.5 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal GPHR_N PF12537.8 GAM18446.1 - 0.43 10.7 3.2 3.3 7.8 0.5 2.4 2 1 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Exonuc_VII_L PF02601.15 GAM18446.1 - 0.45 10.0 11.7 0.55 9.8 11.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Uds1 PF15456.6 GAM18446.1 - 0.45 10.7 6.5 0.9 9.7 6.5 1.4 1 1 0 1 1 1 0 Up-regulated During Septation Fib_alpha PF08702.10 GAM18446.1 - 0.48 10.6 17.7 0.6 10.3 1.3 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1640 PF07798.11 GAM18446.1 - 0.61 10.1 9.0 0.95 9.5 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1664 PF07889.12 GAM18446.1 - 0.69 10.0 10.3 3 7.9 2.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Halogen_Hydrol PF10112.9 GAM18446.1 - 0.72 9.8 5.5 0.17 11.9 0.8 2.1 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Prefoldin PF02996.17 GAM18446.1 - 0.93 9.4 10.1 2.1 8.3 0.2 2.8 2 1 1 3 3 3 0 Prefoldin subunit Muted PF14942.6 GAM18446.1 - 1.4 9.3 15.7 4.1 7.7 13.3 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein ABC2_membrane_3 PF12698.7 GAM18446.1 - 1.5 7.9 9.7 1.8 7.6 9.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1149 PF06619.11 GAM18446.1 - 3.1 8.1 9.6 4.7 7.5 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1149) TFIIA PF03153.13 GAM18446.1 - 4.5 7.2 25.2 5.6 6.9 25.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3584 PF12128.8 GAM18446.1 - 4.8 4.6 17.6 5.9 4.3 17.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fzo_mitofusin PF04799.13 GAM18446.1 - 4.8 6.7 10.6 1.3 8.6 3.5 2.0 1 1 1 2 2 2 0 fzo-like conserved region Spc24 PF08286.11 GAM18446.1 - 7.4 6.9 11.2 0.75 10.1 0.6 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 DUF848 PF05852.11 GAM18446.1 - 8.1 6.6 12.2 5.6 7.1 1.6 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) ApoO PF09769.9 GAM18446.1 - 9 6.3 8.0 3.1e+02 1.3 8.1 2.3 1 1 0 1 1 1 0 Apolipoprotein O Pkinase PF00069.25 GAM18448.1 - 6.6e-47 160.1 0.0 1e-46 159.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18448.1 - 9.8e-25 87.3 0.0 1.4e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM18448.1 - 0.08 12.3 0.0 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Methyltransf_16 PF10294.9 GAM18451.1 - 3.6e-14 52.9 0.1 4.2e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 GAM18451.1 - 0.05 12.9 0.1 0.067 12.5 0.1 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PrmA PF06325.13 GAM18451.1 - 0.085 12.2 0.3 0.11 11.8 0.3 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ras PF00071.22 GAM18452.1 - 6.3e-43 146.2 0.6 1.7e-42 144.8 0.2 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 GAM18452.1 - 1.1e-16 61.1 0.1 1.2e-15 57.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM18452.1 - 1.3e-07 31.3 0.0 2.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM18452.1 - 0.00014 21.9 0.1 0.00067 19.7 0.1 2.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM18452.1 - 0.0043 16.6 0.0 0.0088 15.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GATA PF00320.27 GAM18453.1 - 8.4e-06 25.3 3.2 2.1e-05 24.1 3.2 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF4611 PF15387.6 GAM18453.1 - 0.35 11.1 13.1 0.99 9.7 2.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) PHD PF00628.29 GAM18453.1 - 4.6 7.2 16.2 0.075 12.9 7.0 2.6 2 0 0 2 2 2 0 PHD-finger Zn_ribbon_SprT PF17283.2 GAM18453.1 - 6 6.9 9.6 3.4 7.7 0.1 3.5 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-RING_5 PF14634.6 GAM18453.1 - 6.6 6.8 9.4 1.3 9.0 1.7 2.7 2 0 0 2 2 2 0 zinc-RING finger domain DUF515 PF04415.12 GAM18453.1 - 9.8 4.4 15.9 0.13 10.6 7.9 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF515) Oxysterol_BP PF01237.18 GAM18454.1 - 1.4e-70 238.0 15.6 1.6e-62 211.5 1.3 2.9 1 1 1 2 2 2 2 Oxysterol-binding protein Proteasome PF00227.26 GAM18455.1 - 3.3e-55 186.5 0.1 4.3e-55 186.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM18455.1 - 5.2e-13 48.4 0.1 1e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RhoGAP PF00620.27 GAM18456.1 - 1.2e-35 122.6 0.0 1.9e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain WD40 PF00400.32 GAM18456.1 - 0.0046 17.8 12.6 0.036 14.9 0.3 5.5 6 0 0 6 6 6 1 WD domain, G-beta repeat PALB2_WD40 PF16756.5 GAM18456.1 - 0.0066 15.4 0.9 0.011 14.8 0.1 1.7 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain ANAPC4_WD40 PF12894.7 GAM18456.1 - 0.015 15.6 0.2 15 6.0 0.0 4.1 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain FNIP PF05725.12 GAM18458.1 - 2.1e-80 264.6 18.6 2.2e-12 46.9 0.1 10.4 6 2 3 10 10 10 10 FNIP Repeat DUF1769 PF08588.10 GAM18458.1 - 0.012 15.8 7.9 13 6.1 0.2 6.6 4 2 4 8 8 8 0 Protein of unknown function (DUF1769) Response_reg PF00072.24 GAM18459.1 - 1.5e-27 95.9 1.0 1.4e-21 76.7 0.7 5.0 4 1 0 4 4 4 2 Response regulator receiver domain HATPase_c PF02518.26 GAM18459.1 - 1.5e-26 93.1 0.1 3.4e-26 92.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAM18459.1 - 3.9e-15 55.6 0.2 1.8e-14 53.5 0.2 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 GAM18459.1 - 9e-09 35.5 0.0 2.6e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 GAM18459.1 - 1.9e-08 34.3 0.0 4.2e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 GAM18459.1 - 1.6e-06 28.3 0.0 3.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 GAM18459.1 - 8.4e-05 22.8 0.0 0.00039 20.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold REF PF05755.12 GAM18459.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) SNF2_N PF00176.23 GAM18460.1 - 1e-54 185.6 0.0 2.5e-54 184.3 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM18460.1 - 1.2e-14 54.5 0.0 3e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM18460.1 - 6.7e-08 32.7 0.0 1.8e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAM18460.1 - 0.00062 19.0 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Rad54_N PF08658.10 GAM18460.1 - 0.053 13.7 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Rad54 N terminal AAA_34 PF13872.6 GAM18460.1 - 0.12 11.3 0.4 0.89 8.4 0.4 2.2 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DUF536 PF04394.14 GAM18460.1 - 0.12 12.2 3.9 0.3 11.0 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF536 Sporozoite_P67 PF05642.11 GAM18461.1 - 0.013 13.6 12.6 0.018 13.2 12.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ndc1_Nup PF09531.10 GAM18461.1 - 0.013 14.2 1.1 0.016 13.9 1.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF5083 PF16890.5 GAM18461.1 - 0.027 14.2 0.1 0.049 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) LAP1C PF05609.12 GAM18461.1 - 0.029 13.5 8.3 0.038 13.1 8.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 GAM18461.1 - 0.27 9.5 16.6 0.48 8.7 16.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Mucin PF01456.17 GAM18461.1 - 0.54 10.3 10.0 0.93 9.5 10.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Roughex PF06020.11 GAM18461.1 - 0.86 8.6 10.2 1.4 8.0 10.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein SMC_N PF02463.19 GAM18462.1 - 7.3e-27 94.2 8.1 2.4e-26 92.5 8.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM18462.1 - 2.4e-19 70.6 5.3 2.4e-19 70.6 5.3 5.3 4 1 0 4 4 2 1 AAA domain AAA_15 PF13175.6 GAM18462.1 - 1.3e-07 31.7 29.0 1.3e-07 31.7 29.0 4.1 3 1 0 3 3 3 1 AAA ATPase domain DUF5082 PF16888.5 GAM18462.1 - 0.001 19.3 14.1 0.001 19.3 14.1 7.1 3 2 4 7 7 6 1 Domain of unknown function (DUF5082) Spc7 PF08317.11 GAM18462.1 - 0.0012 17.8 17.4 0.0012 17.8 17.4 4.7 2 2 1 4 4 4 2 Spc7 kinetochore protein AAA_29 PF13555.6 GAM18462.1 - 0.0012 18.6 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GAM18462.1 - 0.0043 16.9 2.3 0.057 13.2 0.2 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system EzrA PF06160.12 GAM18462.1 - 0.048 11.8 59.0 0.3 9.2 14.7 4.8 2 2 1 4 4 4 0 Septation ring formation regulator, EzrA DUF374 PF04028.13 GAM18462.1 - 0.067 12.8 0.1 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF374) ABC_tran PF00005.27 GAM18462.1 - 0.27 11.7 0.1 0.27 11.7 0.1 5.5 3 2 0 3 3 1 0 ABC transporter MukB PF04310.12 GAM18462.1 - 0.41 10.4 3.7 3.1 7.5 0.0 3.3 3 0 0 3 3 3 0 MukB N-terminal BORCS7 PF16088.5 GAM18462.1 - 0.62 10.4 22.5 1.8 8.8 0.3 4.9 4 1 0 4 4 4 0 BLOC-1-related complex sub-unit 7 Sec20 PF03908.13 GAM18462.1 - 1.6 8.7 10.4 6.4 6.8 0.7 4.4 2 1 2 4 4 4 0 Sec20 DUF1664 PF07889.12 GAM18462.1 - 2 8.5 54.3 0.49 10.5 1.2 7.0 5 1 2 7 7 7 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 GAM18462.1 - 5 7.6 49.9 4.8 7.7 5.4 9.1 6 3 3 9 9 9 0 Flagella accessory protein C (FlaC) DUF5426 PF17473.2 GAM18462.1 - 7 6.9 7.2 4.5 7.6 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5426) MHC2-interact PF09307.10 GAM18463.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 CLIP, MHC2 interacting Cyclin PF08613.11 GAM18464.1 - 7.9e-05 23.1 4.9 7.9e-05 23.1 4.9 2.1 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAM18464.1 - 0.0018 18.0 0.8 0.0018 18.0 0.8 2.4 3 0 0 3 3 3 1 Cyclin, N-terminal domain EIF4E-T PF10477.9 GAM18464.1 - 0.74 8.6 19.3 0.68 8.7 14.8 2.0 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Choline_transpo PF04515.12 GAM18465.1 - 4e-101 338.5 36.9 4e-101 338.5 36.9 3.0 3 0 0 3 3 3 2 Plasma-membrane choline transporter DUF2681 PF10883.8 GAM18465.1 - 0.26 11.7 0.8 5.8 7.4 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Pantoate_ligase PF02569.15 GAM18466.1 - 3.4e-90 301.9 0.1 3.9e-90 301.7 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Nit_Regul_Hom PF10126.9 GAM18466.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII DUF896 PF05979.12 GAM18466.1 - 0.15 11.9 0.1 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) SP2 PF03014.14 GAM18467.1 - 0.14 10.6 5.1 0.23 9.8 5.1 1.4 1 0 0 1 1 1 0 Structural protein 2 MAP7 PF05672.11 GAM18467.1 - 9.6 5.9 25.1 0.21 11.3 5.3 2.3 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family DAO PF01266.24 GAM18469.1 - 1e-49 170.0 0.0 1.4e-49 169.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 GAM18469.1 - 4.9e-39 133.1 0.0 8.3e-39 132.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 GAM18469.1 - 2.8e-10 39.9 1.2 0.00015 21.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 GAM18469.1 - 3.1e-07 30.1 2.4 0.0013 18.2 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 GAM18469.1 - 3.7e-05 23.0 3.2 0.014 14.5 0.2 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAM18469.1 - 0.0018 17.6 0.3 0.015 14.6 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM18469.1 - 0.0021 17.4 0.4 0.0091 15.3 0.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM18469.1 - 0.0024 18.0 0.4 0.02 15.1 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM18469.1 - 0.016 14.5 0.5 3.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 GAM18469.1 - 0.022 13.5 0.3 0.042 12.5 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 GAM18469.1 - 0.14 12.8 0.5 0.59 10.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Coiled PF05710.12 GAM18470.1 - 0.027 15.3 9.0 0.035 14.9 9.0 1.2 1 0 0 1 1 1 0 Coiled coil Ribosomal_S7e PF01251.18 GAM18471.1 - 7.7e-77 257.2 4.3 8.9e-77 257.0 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF2924 PF11149.8 GAM18471.1 - 0.026 14.9 0.1 0.041 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Actin PF00022.19 GAM18472.1 - 1.2e-126 422.7 0.0 4e-126 420.9 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAM18472.1 - 0.0084 15.0 0.0 0.24 10.2 0.0 2.4 2 1 0 2 2 2 1 MreB/Mbl protein E3_UbLigase_RBR PF18091.1 GAM18472.1 - 0.13 12.4 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 E3 Ubiquitin Ligase RBR C-terminal domain SLT PF01464.20 GAM18473.1 - 1.2e-10 41.1 0.0 2.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 GAM18473.1 - 0.00019 21.7 3.4 0.0012 19.1 3.4 2.0 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.20 GAM18474.1 - 5.9e-10 38.8 0.0 8.4e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 GAM18474.1 - 2.2e-05 24.7 2.2 0.00011 22.4 2.2 1.9 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family Pkinase PF00069.25 GAM18475.1 - 3.5e-38 131.5 0.0 4.4e-32 111.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18475.1 - 5.1e-28 98.1 0.0 1.9e-27 96.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_1 PF00583.25 GAM18475.1 - 1.1e-06 28.8 0.0 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM18475.1 - 0.005 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM18475.1 - 0.0095 15.9 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase_fungal PF17667.1 GAM18475.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GAM18475.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Acyl-CoA_dh_N PF02771.16 GAM18476.1 - 3.1e-27 95.5 0.0 7.2e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 GAM18476.1 - 6.5e-27 94.6 0.0 1.2e-26 93.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAM18476.1 - 2.5e-22 78.9 0.0 4.4e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM18476.1 - 6.9e-06 26.4 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TMEM252 PF15664.5 GAM18477.1 - 1.4 8.6 3.0 2.3 7.9 1.6 2.1 2 1 0 2 2 2 0 Transmembrane protein 252 family TIG PF01833.24 GAM18478.1 - 3.4e-20 71.9 67.5 0.00025 21.1 2.8 9.0 8 1 1 9 9 9 7 IPT/TIG domain DUF4448 PF14610.6 GAM18478.1 - 0.023 14.5 0.1 0.062 13.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ING PF12998.7 GAM18479.1 - 2.8e-22 79.2 3.8 4.4e-22 78.6 3.8 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAM18479.1 - 2.3e-06 27.4 7.2 3.8e-06 26.7 7.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 GAM18479.1 - 0.0069 16.6 0.1 0.016 15.4 0.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain Cas_CT1975 PF09344.10 GAM18479.1 - 0.0078 15.7 1.7 0.01 15.4 1.7 1.1 1 0 0 1 1 1 1 CT1975-like protein SOGA PF11365.8 GAM18479.1 - 0.022 15.9 0.8 0.043 14.9 0.8 1.5 1 0 0 1 1 1 0 Protein SOGA Elf4 PF07011.11 GAM18479.1 - 0.067 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Early Flowering 4 domain PRP38_assoc PF12871.7 GAM18479.1 - 0.077 13.6 0.2 0.16 12.5 0.2 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1664 PF07889.12 GAM18479.1 - 0.11 12.5 1.3 0.29 11.2 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 GAM18479.1 - 0.76 10.0 4.7 1.5 9.0 4.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 GAM18479.1 - 1 7.2 3.7 1.2 7.0 3.7 1.0 1 0 0 1 1 1 0 Prominin AAA PF00004.29 GAM18480.1 - 2.2e-41 141.3 3.2 4.6e-40 137.1 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAM18480.1 - 1.5e-15 56.9 0.3 3e-15 55.9 0.3 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAM18480.1 - 4.7e-12 45.5 0.1 1.6e-11 43.8 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAM18480.1 - 1.5e-06 28.2 0.6 1.4e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM18480.1 - 5.9e-06 26.8 0.1 0.0077 16.6 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 GAM18480.1 - 9.6e-05 22.6 0.6 0.0004 20.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAM18480.1 - 0.0001 22.1 0.6 0.00047 19.9 0.0 2.3 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAM18480.1 - 0.00075 19.8 1.6 0.077 13.3 0.0 3.0 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 GAM18480.1 - 0.0019 17.7 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 GAM18480.1 - 0.0034 16.8 0.1 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 GAM18480.1 - 0.0036 16.5 0.0 0.0075 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 GAM18480.1 - 0.0048 17.1 0.1 0.018 15.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAM18480.1 - 0.012 15.7 0.1 0.099 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAM18480.1 - 0.023 14.4 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 GAM18480.1 - 0.055 12.8 1.8 0.19 11.0 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.26 GAM18480.1 - 0.057 13.1 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 GAM18480.1 - 0.073 12.6 0.1 0.17 11.4 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 GAM18480.1 - 0.074 13.6 0.1 0.54 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM18480.1 - 0.076 13.4 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GAM18480.1 - 0.078 12.7 0.1 0.26 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain E1-E2_ATPase PF00122.20 GAM18480.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 E1-E2 ATPase AAA_11 PF13086.6 GAM18480.1 - 0.15 11.8 3.1 0.39 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAM18480.1 - 0.31 11.3 2.6 0.96 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-met PF12874.7 GAM18481.1 - 7.5e-13 48.4 9.5 7.6e-07 29.3 0.4 3.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAM18481.1 - 1.7e-07 31.4 3.2 0.0047 17.2 0.2 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAM18481.1 - 1.5e-06 28.5 8.0 9.9e-05 22.6 1.5 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAM18481.1 - 0.0013 19.3 3.6 0.62 11.0 0.0 3.2 2 2 0 2 2 2 2 C2H2-type zinc finger DUF3449 PF11931.8 GAM18481.1 - 0.058 13.2 2.7 1.8 8.3 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3449) zf-U1 PF06220.12 GAM18481.1 - 0.062 13.1 5.5 0.098 12.4 0.3 2.5 2 1 0 2 2 2 0 U1 zinc finger zf-C2H2 PF00096.26 GAM18481.1 - 0.21 12.1 5.3 1.7 9.2 0.1 3.1 2 2 0 2 2 2 0 Zinc finger, C2H2 type DUF3106 PF11304.8 GAM18481.1 - 0.85 10.1 5.9 0.86 10.1 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Pkinase PF00069.25 GAM18484.1 - 2.5e-56 191.0 0.0 3.1e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18484.1 - 7.8e-23 81.1 0.0 1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM18484.1 - 6e-05 22.5 0.0 8.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAM18484.1 - 0.037 13.0 0.1 0.053 12.5 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 GAM18484.1 - 0.044 13.7 0.2 0.15 11.9 0.2 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 GAM18484.1 - 0.045 13.1 0.1 0.07 12.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAM18484.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 adh_short PF00106.25 GAM18486.1 - 4.2e-45 153.6 0.0 6.1e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM18486.1 - 6.9e-36 124.0 0.0 8.8e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM18486.1 - 2.3e-06 27.7 0.0 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM18486.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAM18486.1 - 0.0038 16.6 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 GAM18486.1 - 0.024 14.2 0.0 4.2 6.9 0.0 2.8 2 1 1 3 3 3 0 NmrA-like family CENP-F_leu_zip PF10473.9 GAM18487.1 - 0.00095 19.2 9.3 0.0066 16.5 5.3 2.5 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 GAM18487.1 - 0.0015 19.1 8.3 0.0024 18.4 8.3 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Scaffolding_pro PF11418.8 GAM18487.1 - 0.002 18.7 1.4 0.002 18.7 1.4 1.8 1 1 1 2 2 2 1 Phi29 scaffolding protein FlaC_arch PF05377.11 GAM18487.1 - 0.019 15.3 10.2 0.55 10.7 0.4 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CDK2AP PF09806.9 GAM18487.1 - 0.021 14.9 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein K_channel_TID PF07941.11 GAM18487.1 - 0.24 11.9 4.5 0.35 11.3 4.5 1.2 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Lip_prot_lig_C PF10437.9 GAM18487.1 - 0.27 11.3 4.4 0.41 10.7 0.5 2.3 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus DUF724 PF05266.14 GAM18487.1 - 0.29 11.0 7.3 0.34 10.7 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) YabA PF06156.13 GAM18487.1 - 0.31 11.7 4.6 0.22 12.2 0.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Hemagglutinin PF00509.18 GAM18487.1 - 1.5 7.2 6.8 0.44 8.9 3.7 1.5 1 1 1 2 2 2 0 Haemagglutinin Sec8_exocyst PF04048.14 GAM18489.1 - 9e-17 61.3 0.3 9e-17 61.3 0.3 2.5 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2451 PF10474.9 GAM18489.1 - 7.9e-06 25.8 1.7 2.4e-05 24.3 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) CRAL_TRIO PF00650.20 GAM18490.1 - 1.7e-32 112.4 0.0 2.2e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM18490.1 - 1.5e-06 28.3 0.1 4.6e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAM18490.1 - 0.041 14.0 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain NDK PF00334.19 GAM18491.1 - 6.1e-51 172.0 0.0 7.7e-51 171.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase EF-hand_6 PF13405.6 GAM18492.1 - 8.6e-10 37.8 0.0 3e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 GAM18492.1 - 3.3e-09 35.7 0.0 0.00017 20.9 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 GAM18492.1 - 1.3e-08 34.6 0.0 8.8e-06 25.5 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM18492.1 - 9.6e-08 31.2 0.0 0.00075 18.9 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAM18492.1 - 0.00024 21.5 0.0 0.00035 21.0 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.6 GAM18492.1 - 0.17 11.8 0.5 0.52 10.2 0.2 1.8 1 1 1 2 2 2 0 EF hand TLD PF07534.16 GAM18493.1 - 2.4e-32 112.0 0.3 5e-32 111.0 0.3 1.6 1 0 0 1 1 1 1 TLD LysM PF01476.20 GAM18493.1 - 2.1e-07 30.9 0.3 6.9e-07 29.2 0.1 2.0 2 0 0 2 2 2 1 LysM domain GRAM PF02893.20 GAM18493.1 - 0.00025 20.9 0.2 0.00092 19.1 0.1 2.0 1 1 1 2 2 2 1 GRAM domain YppF PF14178.6 GAM18493.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 YppF-like protein Tweety PF04906.13 GAM18494.1 - 6.9e-07 28.3 8.5 4.3e-05 22.4 7.2 3.0 2 1 0 2 2 2 1 Tweety DUF1772 PF08592.11 GAM18494.1 - 0.098 13.0 2.0 2.3 8.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2207 PF09972.9 GAM18494.1 - 0.73 8.5 14.8 0.19 10.4 0.6 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Tweety PF04906.13 GAM18496.1 - 7.7e-06 24.8 12.9 0.0002 20.2 12.9 2.4 1 1 0 1 1 1 1 Tweety Prominin PF05478.11 GAM18496.1 - 0.00075 17.6 0.2 0.00075 17.6 0.2 2.1 1 1 1 2 2 2 1 Prominin Wzy_C PF04932.15 GAM18496.1 - 0.0093 15.6 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 1 O-Antigen ligase DUF2207 PF09972.9 GAM18496.1 - 0.017 13.9 0.2 0.017 13.9 0.2 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.8 GAM18496.1 - 0.036 14.0 0.1 0.036 14.0 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) TMCO5 PF14992.6 GAM18496.1 - 0.053 13.1 0.6 0.088 12.4 0.6 1.3 1 0 0 1 1 1 0 TMCO5 family DUF1980 PF09323.10 GAM18496.1 - 0.072 13.0 3.4 8 6.3 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) ABC2_membrane_2 PF12679.7 GAM18496.1 - 0.2 10.9 6.0 0.19 11.0 2.7 2.4 3 0 0 3 3 3 0 ABC-2 family transporter protein TMEM173 PF15009.6 GAM18496.1 - 0.31 10.2 7.0 0.33 10.1 2.5 2.3 1 1 0 2 2 2 0 Transmembrane protein 173 FAM117 PF15388.6 GAM18497.1 - 0.028 13.9 0.3 0.049 13.1 0.3 1.3 1 0 0 1 1 1 0 Protein Family FAM117 Pkinase PF00069.25 GAM18498.1 - 3.3e-57 193.8 0.0 4.2e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18498.1 - 3e-16 59.5 0.0 4.3e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM18498.1 - 2.6e-06 27.5 0.1 7e-05 22.9 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAM18498.1 - 0.0057 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ABC1 PF03109.16 GAM18498.1 - 0.045 13.9 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC1 family DUF5482 PF17579.2 GAM18498.1 - 0.055 13.3 0.4 0.1 12.5 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5482) Mito_carr PF00153.27 GAM18499.1 - 9.9e-67 220.9 0.8 5.4e-24 83.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CcmE PF03100.15 GAM18500.1 - 0.0044 17.0 0.1 0.0058 16.6 0.1 1.2 1 0 0 1 1 1 1 CcmE O-antigen_lig PF13425.6 GAM18500.1 - 0.0055 15.6 0.8 0.0064 15.3 0.8 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein DUF2681 PF10883.8 GAM18500.1 - 0.0065 16.8 2.7 0.014 15.8 2.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) EphA2_TM PF14575.6 GAM18500.1 - 0.0089 16.9 1.2 0.011 16.7 0.2 1.6 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 GAM18500.1 - 0.012 15.2 0.7 0.02 14.5 0.7 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family ArsP_1 PF03773.13 GAM18500.1 - 0.014 14.5 0.2 0.019 14.1 0.2 1.1 1 0 0 1 1 1 0 Predicted permease Ly49 PF08391.10 GAM18500.1 - 0.036 14.4 7.3 0.079 13.3 7.3 1.7 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Dpy19 PF10034.9 GAM18500.1 - 0.046 11.9 0.2 0.046 11.9 0.2 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Conotoxin PF02950.17 GAM18500.1 - 0.046 14.7 0.2 0.046 14.7 0.2 2.7 3 0 0 3 3 3 0 Conotoxin Bap31 PF05529.12 GAM18500.1 - 0.081 12.8 1.2 0.12 12.3 1.2 1.2 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region DUF2232 PF09991.9 GAM18500.1 - 0.12 11.5 1.1 0.15 11.2 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ureide_permease PF07168.11 GAM18500.1 - 0.16 10.7 1.2 0.2 10.4 0.3 1.5 1 1 1 2 2 2 0 Ureide permease ABC2_membrane_2 PF12679.7 GAM18500.1 - 0.2 10.9 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Cwf_Cwc_15 PF04889.12 GAM18500.1 - 0.22 11.3 19.1 0.25 11.0 19.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ABC_export PF16962.5 GAM18500.1 - 0.22 9.9 0.1 0.28 9.6 0.1 1.0 1 0 0 1 1 1 0 Putative ABC exporter Ac76 PF05814.11 GAM18500.1 - 0.26 11.3 2.3 0.42 10.6 2.3 1.3 1 0 0 1 1 1 0 Orf76 (Ac76) Ctr PF04145.15 GAM18500.1 - 0.47 11.1 1.4 0.79 10.3 1.4 1.6 1 1 0 1 1 1 0 Ctr copper transporter family SIT PF15330.6 GAM18500.1 - 1.2 9.6 7.3 6.7 7.2 7.3 2.1 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3464 PF11947.8 GAM18500.1 - 2.4 7.9 6.5 10 5.8 0.3 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 TMEM51 PF15345.6 GAM18500.1 - 3.6 7.4 8.8 15 5.4 8.8 1.9 1 1 0 1 1 1 0 Transmembrane protein 51 DUF4834 PF16118.5 GAM18500.1 - 3.9 8.5 12.5 34 5.5 12.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Ribosomal_L18 PF17135.4 GAM18501.1 - 8e-69 230.8 8.7 4.2e-68 228.4 8.7 1.8 1 1 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 GAM18501.1 - 0.018 15.7 1.6 0.033 14.9 1.6 1.5 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Folate_carrier PF01770.18 GAM18503.1 - 2.8e-57 194.3 36.0 6.2e-32 110.9 16.5 2.1 1 1 1 2 2 2 2 Reduced folate carrier MFS_1 PF07690.16 GAM18503.1 - 1.8e-10 40.3 28.7 1.8e-10 40.3 28.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_transf_41 PF13844.6 GAM18503.1 - 0.045 12.2 0.1 0.073 11.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 zf-C2H2_jaz PF12171.8 GAM18504.1 - 1.4e-06 28.4 3.9 1.4e-06 28.4 3.9 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM18504.1 - 0.0013 19.1 3.5 0.0013 19.1 3.5 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-CRD PF17979.1 GAM18505.1 - 4.4e-31 108.1 4.2 4.4e-31 108.1 4.2 3.0 2 1 1 3 3 2 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 GAM18505.1 - 7.7e-17 61.4 0.4 1.7e-15 57.1 0.1 2.5 2 0 0 2 2 2 1 FHA domain zf-C3HC4_3 PF13920.6 GAM18505.1 - 7.8e-06 25.6 31.2 1.6e-05 24.7 13.0 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM18505.1 - 4.4e-05 23.2 16.9 4.4e-05 23.2 16.9 2.8 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCHH PF10283.9 GAM18505.1 - 6.7e-05 22.8 5.3 0.00034 20.5 5.3 2.4 1 0 0 1 1 1 1 PBZ domain zf-RING_2 PF13639.6 GAM18505.1 - 0.00042 20.6 17.0 0.00042 20.6 17.0 3.2 2 1 0 2 2 2 1 Ring finger domain Yop-YscD_cpl PF16697.5 GAM18505.1 - 0.00058 20.1 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 GAM18505.1 - 0.0016 18.3 17.7 0.0016 18.3 17.7 3.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) FHA_2 PF17913.1 GAM18505.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 FHA domain MLD PF11647.8 GAM18505.1 - 0.019 15.2 0.3 0.16 12.3 0.1 2.4 2 0 0 2 2 2 0 Membrane Localization Domain Menin PF05053.13 GAM18505.1 - 0.16 10.3 6.8 0.28 9.5 6.8 1.3 1 0 0 1 1 1 0 Menin zf-RING_6 PF14835.6 GAM18505.1 - 0.31 10.9 13.5 0.11 12.4 6.1 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein MCM6_C PF18263.1 GAM18505.1 - 0.87 9.8 7.7 0.67 10.2 2.4 2.5 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain zf-RING_10 PF16685.5 GAM18505.1 - 2.2 8.5 28.0 0.32 11.1 10.7 2.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 GAM18505.1 - 9.5 6.2 30.0 0.083 12.8 12.5 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RhoGEF PF00621.20 GAM18506.1 - 0.12 12.5 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 RhoGEF domain Pkinase_Tyr PF07714.17 GAM18507.1 - 3e-52 177.5 0.0 4.5e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM18507.1 - 8.6e-45 153.2 0.0 1.4e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 GAM18507.1 - 1e-33 116.8 0.0 1.8e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 GAM18507.1 - 7.8e-25 87.4 0.1 1.8e-24 86.2 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM18507.1 - 2.9e-15 56.2 0.2 6e-15 55.2 0.2 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.21 GAM18507.1 - 4.5e-11 42.5 0.0 8.1e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM18507.1 - 2.3e-05 23.8 0.1 5.9e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region LRR_8 PF13855.6 GAM18507.1 - 6.8e-05 22.6 4.0 0.00013 21.7 2.8 2.2 2 0 0 2 2 2 1 Leucine rich repeat MMR_HSR1 PF01926.23 GAM18507.1 - 8.3e-05 22.6 0.1 0.00031 20.8 0.0 2.0 2 0 0 2 2 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAM18507.1 - 0.00054 20.5 1.4 0.0019 18.7 1.1 2.0 1 1 1 2 2 2 1 ABC transporter LRR_4 PF12799.7 GAM18507.1 - 0.0014 18.9 5.5 0.0019 18.5 2.0 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) RsgA_GTPase PF03193.16 GAM18507.1 - 0.0021 18.0 0.1 0.015 15.2 0.2 2.4 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 GAM18507.1 - 0.013 14.7 0.5 0.029 13.7 0.5 1.4 1 0 0 1 1 1 0 Septin AAA_18 PF13238.6 GAM18507.1 - 0.023 15.2 0.5 5.2 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAM18507.1 - 0.067 12.7 0.3 0.14 11.6 0.3 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 GAM18507.1 - 0.067 12.9 0.4 0.2 11.4 0.4 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 GAM18507.1 - 0.069 12.4 0.1 0.65 9.2 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin MORN PF02493.20 GAM18508.1 - 4.5e-12 45.1 16.2 0.0026 17.5 0.2 6.2 6 0 0 6 6 6 4 MORN repeat SET PF00856.28 GAM18508.1 - 1.8e-05 25.2 7.1 0.00016 22.1 0.7 3.0 2 1 0 2 2 2 1 SET domain Sec10 PF07393.11 GAM18508.1 - 0.2 10.1 4.4 0.22 9.9 4.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Presenilin PF01080.17 GAM18508.1 - 0.42 9.3 12.6 0.51 9.0 12.6 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GAM18508.1 - 1.6 7.9 5.7 2 7.6 5.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Raptor_N PF14538.6 GAM18508.1 - 1.8 8.5 7.3 6.9 6.6 0.0 2.8 2 1 1 3 3 3 0 Raptor N-terminal CASPase like domain FNIP PF05725.12 GAM18509.1 - 4e-43 145.3 33.6 3.7e-10 39.8 1.0 7.5 7 0 0 7 7 7 7 FNIP Repeat FSH1 PF03959.13 GAM18510.1 - 2.1e-48 164.8 0.4 4.3e-47 160.5 0.4 2.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 GAM18510.1 - 0.033 13.8 2.4 0.17 11.5 2.4 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Menin PF05053.13 GAM18510.1 - 0.13 10.6 1.8 0.16 10.3 1.8 1.1 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 GAM18510.1 - 0.33 11.5 9.1 0.66 10.6 9.1 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain SK_channel PF03530.14 GAM18511.1 - 8.3e-06 25.8 1.8 8.3e-06 25.8 1.8 2.3 2 1 0 2 2 2 1 Calcium-activated SK potassium channel Pmp3 PF01679.17 GAM18512.1 - 3.2e-21 75.3 11.7 3.5e-21 75.1 11.7 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF872 PF05915.12 GAM18512.1 - 0.15 12.3 0.2 0.15 12.3 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Condensin2nSMC PF12422.8 GAM18513.1 - 0.052 13.7 0.2 0.061 13.5 0.2 1.1 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Mod_r PF07200.13 GAM18514.1 - 4.4e-23 82.0 23.7 4.4e-23 82.0 23.7 1.8 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein KxDL PF10241.9 GAM18514.1 - 1 9.7 11.2 2.4 8.5 6.7 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein Menin PF05053.13 GAM18515.1 - 1.6 7.0 3.1 2 6.7 3.1 1.1 1 0 0 1 1 1 0 Menin DUF4551 PF15087.6 GAM18515.1 - 2.1 7.1 6.1 2.4 6.9 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ten_N PF06484.12 GAM18515.1 - 6 6.6 10.3 7.3 6.4 10.3 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region DUF2461 PF09365.10 GAM18516.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) Voltage_CLC PF00654.20 GAM18517.1 - 3.4e-79 266.7 20.3 3.4e-79 266.7 20.3 1.4 1 1 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 GAM18517.1 - 1.4e-11 44.6 1.9 9.9e-05 22.7 0.1 3.2 3 0 0 3 3 3 2 CBS domain Sigma70_r1_1 PF03979.14 GAM18517.1 - 0.1 12.6 0.0 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 GST_C_3 PF14497.6 GAM18518.1 - 9.6e-19 67.4 0.0 1.5e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM18518.1 - 1.7e-07 31.5 0.0 4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM18518.1 - 1.9e-07 31.2 0.0 4.6e-07 30.0 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM18518.1 - 0.0056 16.7 0.1 0.015 15.3 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM18518.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.13 GAM18518.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Cytomega_UL84 PF06284.11 GAM18518.1 - 0.25 9.7 0.0 0.28 9.6 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein WD40 PF00400.32 GAM18519.1 - 5.6e-34 115.6 12.5 2.2e-07 31.4 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Striatin PF08232.12 GAM18519.1 - 1.6e-25 90.5 19.5 6.4e-24 85.3 19.4 3.0 1 1 0 1 1 1 1 Striatin family ANAPC4_WD40 PF12894.7 GAM18519.1 - 5.6e-13 49.0 0.1 0.018 15.3 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM18519.1 - 0.00011 21.0 0.6 1 7.9 0.2 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAM18519.1 - 0.00019 20.3 4.5 0.054 12.2 0.1 4.6 3 1 2 6 6 6 1 Nup133 N terminal like Ge1_WD40 PF16529.5 GAM18519.1 - 0.0031 16.5 0.0 0.97 8.3 0.0 2.9 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Androgen_recep PF02166.16 GAM18519.1 - 0.039 12.8 2.9 0.074 11.9 2.9 1.4 1 0 0 1 1 1 0 Androgen receptor PQQ_2 PF13360.6 GAM18519.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 PQQ-like domain Mak10 PF04112.13 GAM18520.1 - 2.3e-20 72.8 2.7 2.6e-17 62.8 0.1 3.2 2 1 1 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF3987 PF13148.6 GAM18520.1 - 0.34 9.9 4.3 0.69 8.9 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AP3D1 PF06375.11 GAM18520.1 - 7.4 6.8 9.0 0.69 10.1 2.4 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF1325 PF07039.11 GAM18521.1 - 2.4e-32 111.8 1.1 5.4e-32 110.7 1.1 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 GAM18521.1 - 1.6e-06 27.8 0.0 4.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 GAM18521.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 GAM18521.1 - 0.062 13.1 0.0 9.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Sigma_reg_C PF13791.6 GAM18522.1 - 0.011 15.9 0.2 0.02 15.1 0.0 1.4 2 0 0 2 2 2 0 Sigma factor regulator C-terminal SWIM PF04434.17 GAM18523.1 - 0.0022 17.6 2.2 0.0041 16.8 2.2 1.4 1 0 0 1 1 1 1 SWIM zinc finger GRAM PF02893.20 GAM18524.1 - 1.9e-25 89.0 5.9 2.1e-14 53.4 1.9 2.4 2 0 0 2 2 2 2 GRAM domain Vps36_ESCRT-II PF11605.8 GAM18524.1 - 2.2e-06 27.7 1.9 0.0095 16.1 0.3 2.6 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 GAM18524.1 - 0.00043 20.5 3.8 0.52 10.7 0.1 3.3 3 0 0 3 3 3 2 TFIIH p62 subunit, N-terminal domain DUF2113 PF09886.9 GAM18524.1 - 0.0057 16.0 1.0 1.4 8.2 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2113) RhoGAP PF00620.27 GAM18525.1 - 3.4e-25 88.6 0.0 7.4e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 GAM18525.1 - 9.8e-15 54.7 0.0 1.4e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Patatin PF01734.22 GAM18527.1 - 1.5e-19 71.0 0.0 1.5e-19 71.0 0.0 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase SWI-SNF_Ssr4 PF08549.10 GAM18527.1 - 1.2 7.7 5.2 1.6 7.3 5.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Dicty_REP PF05086.12 GAM18527.1 - 2.6 5.9 10.6 4.5 5.1 10.6 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Aha1_N PF09229.11 GAM18528.1 - 2.9e-31 108.5 1.6 5.3e-31 107.7 1.6 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 GAM18528.1 - 3.5e-15 56.3 0.1 9.7e-15 54.9 0.0 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein INCENP_ARK-bind PF03941.15 GAM18529.1 - 1.8e-09 37.4 0.6 1.8e-09 37.4 0.6 4.7 4 1 0 4 4 4 1 Inner centromere protein, ARK binding region Exo_endo_phos PF03372.23 GAM18530.1 - 4e-09 36.3 0.1 7.6e-09 35.4 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Guanylate_cyc PF00211.20 GAM18531.1 - 5.3e-78 260.9 1.8 2.3e-40 138.2 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 GAM18531.1 - 2.1e-05 24.0 7.8 0.0064 15.9 0.1 3.3 3 0 0 3 3 3 2 Heme NO binding associated Zip PF02535.22 GAM18531.1 - 0.086 12.0 0.0 0.086 12.0 0.0 2.8 3 1 0 3 3 3 0 ZIP Zinc transporter ECH_2 PF16113.5 GAM18532.1 - 4e-98 329.0 0.0 5.1e-98 328.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAM18532.1 - 8.1e-25 87.6 0.0 1.3e-24 86.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_C26 PF07722.13 GAM18533.1 - 7.2e-19 68.4 0.0 2.9e-18 66.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 GAM18533.1 - 1.6e-08 34.5 0.0 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PS_pyruv_trans PF04230.13 GAM18533.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Trs65 PF12735.7 GAM18534.1 - 6.7e-07 29.0 4.8 6.7e-07 29.0 4.8 3.0 2 2 0 2 2 2 1 TRAPP trafficking subunit Trs65 A2M PF00207.22 GAM18534.1 - 0.012 15.5 0.1 0.038 13.8 0.1 1.9 1 0 0 1 1 1 0 Alpha-2-macroglobulin family Ank_5 PF13857.6 GAM18536.1 - 3.3e-18 65.5 1.8 0.0016 18.7 0.0 6.9 2 2 6 8 8 8 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM18536.1 - 8.5e-18 64.7 0.2 9.4e-08 32.5 0.0 3.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM18536.1 - 6.6e-15 55.3 0.1 0.0024 18.4 0.0 5.1 4 2 2 6 6 6 4 Ankyrin repeats (many copies) DUF5049 PF16468.5 GAM18536.1 - 1.3e-11 44.2 1.6 0.46 10.4 0.0 6.9 3 2 5 8 8 8 4 Domain of unknown function (DUF5049) Ank_3 PF13606.6 GAM18536.1 - 2.5e-06 27.4 0.1 96 4.1 0.0 7.0 7 2 1 8 8 8 0 Ankyrin repeat Tom37 PF10568.9 GAM18536.1 - 0.011 16.0 0.1 1.3 9.4 0.0 3.0 2 1 0 2 2 2 0 Outer mitochondrial membrane transport complex protein VbhA PF18495.1 GAM18536.1 - 0.018 14.9 0.4 7.8 6.5 0.0 3.7 3 1 2 5 5 5 0 Antitoxin VbhA Ank PF00023.30 GAM18536.1 - 0.041 14.3 0.0 1e+02 3.6 0.0 4.5 3 2 0 3 3 3 0 Ankyrin repeat LCAT PF02450.15 GAM18537.1 - 4.2e-47 161.2 0.1 5.3e-47 160.8 0.1 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 GAM18537.1 - 4e-05 23.5 0.0 0.00065 19.5 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 GAM18537.1 - 0.00036 19.9 0.0 0.00054 19.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 GAM18537.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 GAM18537.1 - 0.0086 16.7 0.0 0.014 16.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 GAM18537.1 - 0.014 15.3 0.0 0.088 12.7 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_1 PF00561.20 GAM18537.1 - 0.018 14.7 1.0 3.4 7.2 0.1 3.0 2 1 1 3 3 3 0 alpha/beta hydrolase fold CBM_25 PF03423.13 GAM18537.1 - 0.021 15.1 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) DUF676 PF05057.14 GAM18537.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF915 PF06028.11 GAM18537.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) F-box PF00646.33 GAM18539.1 - 0.0053 16.6 0.4 0.023 14.6 0.4 2.2 1 0 0 1 1 1 1 F-box domain DUF4404 PF14357.6 GAM18539.1 - 0.083 13.5 0.0 0.36 11.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Bax1-I PF01027.20 GAM18540.1 - 7.7e-28 97.7 27.6 9.1e-28 97.5 27.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pox_A14 PF05767.12 GAM18540.1 - 0.0021 18.2 0.9 0.0021 18.2 0.9 2.5 2 1 0 2 2 2 1 Poxvirus virion envelope protein A14 Archaeal_AmoA PF12942.7 GAM18540.1 - 0.036 13.8 5.4 0.38 10.4 0.2 2.3 1 1 1 2 2 2 0 Archaeal ammonia monooxygenase subunit A (AmoA) CPP1-like PF11833.8 GAM18540.1 - 9.3 5.9 9.9 1.3 8.6 5.4 1.9 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PriC PF07445.12 GAM18541.1 - 1.3 8.9 11.4 4.1 7.3 9.6 2.3 1 1 1 2 2 2 0 Primosomal replication protein priC DUF2207 PF09972.9 GAM18542.1 - 0.034 12.9 0.1 0.04 12.7 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ATP_synt_H PF05493.13 GAM18543.1 - 4e-16 59.2 7.0 5.1e-16 58.9 7.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit H TRAM_LAG1_CLN8 PF03798.16 GAM18544.1 - 7.2e-22 78.1 11.2 7.2e-22 78.1 11.2 1.5 2 0 0 2 2 2 1 TLC domain Ank_2 PF12796.7 GAM18545.1 - 8.3e-49 164.1 31.4 3.7e-10 40.2 0.1 6.9 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM18545.1 - 7.6e-35 118.8 17.4 1.1e-05 25.9 0.2 9.3 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM18545.1 - 3.1e-34 116.6 25.9 0.0024 18.2 0.2 13.4 2 1 12 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM18545.1 - 1.2e-22 77.6 9.1 4.3 8.2 0.0 12.8 10 2 3 13 13 13 6 Ankyrin repeat Ank PF00023.30 GAM18545.1 - 1.2e-06 28.7 11.9 33 5.2 0.0 10.5 8 4 2 10 10 10 0 Ankyrin repeat DUF5049 PF16468.5 GAM18545.1 - 3.1e-05 23.8 4.1 3.1 7.8 0.0 7.7 8 2 2 10 10 10 1 Domain of unknown function (DUF5049) DUF1707 PF08044.11 GAM18545.1 - 6.5 6.9 8.1 31 4.7 0.1 5.6 8 0 0 8 8 8 0 Domain of unknown function (DUF1707) Pkinase PF00069.25 GAM18546.1 - 4.1e-48 164.0 0.4 9.3e-48 162.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain RhoGEF PF00621.20 GAM18546.1 - 8.9e-38 130.4 0.7 8.9e-38 130.4 0.7 2.6 2 1 0 2 2 2 1 RhoGEF domain Pkinase_Tyr PF07714.17 GAM18546.1 - 2.3e-37 128.7 0.0 4.1e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase IQ_SEC7_PH PF16453.5 GAM18546.1 - 1.7e-10 41.0 0.1 4.6e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 PH domain PH PF00169.29 GAM18546.1 - 1.4e-05 25.5 0.0 6.7e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 GAM18546.1 - 0.0064 15.3 0.0 0.0064 15.3 0.0 2.8 2 1 0 2 2 1 1 Fungal protein kinase APH PF01636.23 GAM18546.1 - 0.064 13.2 3.8 0.27 11.1 0.0 2.9 3 1 0 4 4 4 0 Phosphotransferase enzyme family PH_13 PF16652.5 GAM18546.1 - 0.16 11.8 0.0 0.16 11.8 0.0 3.4 3 1 0 3 3 2 0 Pleckstrin homology domain FapA PF03961.13 GAM18546.1 - 1 7.9 6.4 3.1 6.3 6.4 1.7 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cauli_AT PF03233.13 GAM18546.1 - 1.4 8.8 8.8 6.1 6.7 3.0 3.0 2 0 0 2 2 2 0 Aphid transmission protein CCDC106 PF15794.5 GAM18546.1 - 1.7 8.3 16.7 0.53 9.9 5.7 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF1980 PF09323.10 GAM18546.1 - 2.8 7.8 6.2 8.6 6.2 6.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) ADH_zinc_N PF00107.26 GAM18547.1 - 1.4e-21 76.8 0.0 2.5e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM18547.1 - 1.9e-10 40.6 0.1 1.8e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM18547.1 - 1.5e-07 32.6 0.0 5.3e-07 30.7 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM18547.1 - 7.4e-05 22.1 1.3 0.00011 21.6 1.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF4054 PF13262.6 GAM18547.1 - 0.086 12.9 0.3 0.28 11.2 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4054) DUF1542 PF07564.11 GAM18548.1 - 0.033 14.3 0.2 0.97 9.6 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DNApol_Exo PF18136.1 GAM18548.1 - 0.039 13.1 0.9 0.063 12.4 0.9 1.3 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain CENP-H PF05837.12 GAM18548.1 - 2 8.8 6.5 1.6 9.2 4.0 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FH2 PF02181.23 GAM18549.1 - 1.6e-81 274.3 1.4 1.6e-81 274.3 1.4 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain PRIMA1 PF16101.5 GAM18549.1 - 0.2 11.7 8.0 0.78 9.8 8.0 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Totivirus_coat PF05518.11 GAM18549.1 - 2.1 6.3 5.9 3.4 5.6 5.9 1.2 1 0 0 1 1 1 0 Totivirus coat protein bZIP_2 PF07716.15 GAM18550.1 - 1.5e-08 34.6 4.8 3.6e-08 33.4 4.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAM18550.1 - 4.1e-07 30.0 10.9 5.5e-07 29.6 4.9 2.5 2 0 0 2 2 2 1 bZIP transcription factor TSC22 PF01166.18 GAM18550.1 - 0.067 13.5 0.3 0.97 9.8 0.1 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family Herpes_BLRF2 PF05812.12 GAM18550.1 - 0.079 13.1 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF977 PF06163.11 GAM18550.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Pro_isomerase PF00160.21 GAM18552.1 - 2.6e-46 157.8 0.8 2.9e-46 157.6 0.8 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FNIP PF05725.12 GAM18553.1 - 2.2e-63 210.2 47.3 2.4e-12 46.8 1.1 10.2 6 2 3 10 10 10 9 FNIP Repeat Ank_2 PF12796.7 GAM18554.1 - 1.7e-33 115.1 20.9 8.6e-10 39.1 1.8 6.5 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM18554.1 - 3.6e-32 110.3 25.2 4.5e-06 27.1 0.1 8.9 7 3 2 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM18554.1 - 3.3e-25 87.8 26.8 0.0043 17.3 0.1 13.2 2 2 12 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM18554.1 - 2.5e-24 82.7 16.7 2.1 9.2 0.1 14.3 13 1 1 14 14 14 5 Ankyrin repeat Ank PF00023.30 GAM18554.1 - 0.00066 20.0 18.2 54 4.5 1.7 9.8 6 3 3 9 9 9 0 Ankyrin repeat DUF5049 PF16468.5 GAM18554.1 - 0.002 18.0 1.9 23 5.0 0.0 6.2 5 2 3 8 8 8 0 Domain of unknown function (DUF5049) DUF1707 PF08044.11 GAM18554.1 - 0.016 15.2 5.8 16 5.6 0.1 5.4 5 1 0 5 5 5 0 Domain of unknown function (DUF1707) AhpC-TSA PF00578.21 GAM18554.1 - 0.064 13.2 0.0 6.5 6.7 0.0 3.1 3 1 0 3 3 3 0 AhpC/TSA family LPMO_10 PF03067.15 GAM18556.1 - 4.1e-18 66.8 0.1 4.8e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading WD40 PF00400.32 GAM18557.1 - 3.9e-13 49.6 1.9 0.016 16.0 0.1 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM18557.1 - 1.5e-05 25.2 0.0 1.2 9.5 0.0 4.5 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 GAM18557.1 - 0.02 14.1 0.0 0.048 12.9 0.0 1.6 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Orn_Arg_deC_N PF02784.16 GAM18558.1 - 1.4e-30 106.5 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 GAM18558.1 - 3.7e-20 72.0 0.0 4e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Claudin_2 PF13903.6 GAM18559.1 - 0.0054 16.5 4.3 0.0068 16.2 2.1 2.0 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Bac_rhodopsin PF01036.18 GAM18559.1 - 0.0071 15.9 0.4 0.0071 15.9 0.4 1.7 2 0 0 2 2 2 1 Bacteriorhodopsin-like protein LapA_dom PF06305.11 GAM18559.1 - 0.17 11.7 3.4 0.75 9.7 0.0 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2975 PF11188.8 GAM18559.1 - 0.21 11.5 5.3 0.25 11.2 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) SUR7 PF06687.12 GAM18559.1 - 1.7 8.2 10.4 1 8.9 2.6 2.4 1 1 1 2 2 2 0 SUR7/PalI family EphA2_TM PF14575.6 GAM18559.1 - 2 9.4 5.3 12 6.8 0.1 3.2 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Kelch_6 PF13964.6 GAM18560.1 - 9.7e-07 28.9 2.6 0.064 13.6 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 GAM18560.1 - 5.2e-05 23.2 1.4 0.045 13.8 0.0 2.9 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM18560.1 - 0.0001 21.8 2.0 0.093 12.3 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 GAM18560.1 - 0.00048 20.0 0.4 0.63 10.1 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 GAM18560.1 - 0.003 17.5 1.5 0.52 10.4 0.3 2.5 2 0 0 2 2 2 2 Kelch motif Orthopox_A5L PF06193.11 GAM18560.1 - 0.008 15.6 0.6 2.6 7.4 0.1 2.2 2 0 0 2 2 2 2 Orthopoxvirus A5L protein-like S1 PF00575.23 GAM18561.1 - 5e-14 52.4 0.7 9.6e-14 51.5 0.0 1.7 2 0 0 2 2 2 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 GAM18561.1 - 9.8e-14 51.5 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 GAM18561.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Ion_trans PF00520.31 GAM18562.1 - 0.64 9.2 15.2 1.2 8.4 15.0 1.4 1 1 0 1 1 1 0 Ion transport protein Sacchrp_dh_C PF16653.5 GAM18563.1 - 2.3e-75 254.1 0.0 6.9e-75 252.6 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 GAM18563.1 - 1.4e-28 99.8 0.1 5.3e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 GAM18563.1 - 5.9e-23 81.6 0.1 1.2e-22 80.6 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 GAM18563.1 - 6.1e-09 35.5 0.0 0.00012 21.4 0.0 3.7 4 0 0 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 GAM18563.1 - 0.00017 21.6 0.1 0.00048 20.2 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 GAM18563.1 - 0.0066 16.6 0.2 0.015 15.4 0.2 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 GAM18563.1 - 0.032 14.5 0.2 0.085 13.1 0.2 1.7 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 GAM18563.1 - 0.032 15.0 0.0 0.072 13.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1473 PF07341.11 GAM18563.1 - 0.039 13.7 0.2 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1473) TMEM192 PF14802.6 GAM18563.1 - 0.17 11.0 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 TMEM192 family UCH PF00443.29 GAM18565.1 - 5.1e-42 144.2 8.0 5.1e-42 144.2 8.0 2.2 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM18565.1 - 4.6e-10 39.6 18.8 4.6e-10 39.6 18.8 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 GAM18565.1 - 0.005 16.4 3.1 0.0088 15.5 0.1 2.7 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Cyt-b5 PF00173.28 GAM18566.1 - 7.6e-18 64.4 0.1 1.4e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 GAM18566.1 - 4.6e-14 52.9 15.3 4.6e-14 52.9 15.3 1.9 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily ACOX PF01756.19 GAM18567.1 - 7.9e-27 94.0 0.0 1.3e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 GAM18567.1 - 3.7e-15 55.9 0.1 7e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAM18567.1 - 2.4e-10 40.8 0.2 4.2e-10 40.0 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3963 PF13124.6 GAM18567.1 - 0.29 11.1 0.8 5.7 7.0 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) 2OG-FeII_Oxy_3 PF13640.6 GAM18569.1 - 1.5e-12 48.3 0.0 3.9e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Actin PF00022.19 GAM18569.1 - 4.2e-10 38.8 0.2 7.1e-07 28.2 0.0 2.2 1 1 1 2 2 2 2 Actin Pox_C4_C10 PF03336.13 GAM18569.1 - 0.0029 16.8 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 Poxvirus C4/C10 protein PP2C PF00481.21 GAM18570.1 - 3.6e-56 190.6 0.0 6.2e-56 189.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 GAM18570.1 - 3.9e-38 129.0 71.0 1.8e-08 34.0 7.1 10.2 4 2 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 GAM18570.1 - 3e-37 126.0 72.0 4.4e-06 26.9 5.7 11.7 8 3 4 12 12 12 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAM18570.1 - 5.5e-10 39.0 17.2 0.027 14.0 0.4 4.5 4 0 0 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 GAM18570.1 - 4.3e-08 32.6 56.7 4.6 8.2 0.0 17.2 18 1 0 18 18 18 3 Leucine Rich Repeat PP2C_2 PF13672.6 GAM18570.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.6 GAM18570.1 - 0.2 11.8 66.1 0.27 11.4 0.1 14.6 16 0 0 16 16 16 0 Leucine Rich repeat Alpha_L_fucos PF01120.17 GAM18571.1 - 1.8e-120 402.6 3.3 2.2e-120 402.3 3.3 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 GAM18571.1 - 1.4e-17 64.0 0.3 2.7e-17 63.1 0.3 1.4 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain 7tm_2 PF00002.24 GAM18572.1 - 2.7e-06 26.9 15.8 4.7e-06 26.1 15.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 GAM18572.1 - 0.00042 19.5 20.3 0.00065 18.8 20.3 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DHHC PF01529.20 GAM18572.1 - 0.014 15.5 3.4 0.014 15.5 3.4 3.4 3 1 1 4 4 4 0 DHHC palmitoyltransferase Dicty_CAR PF05462.11 GAM18573.1 - 5.1e-08 32.4 14.2 8.8e-08 31.6 14.2 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 GAM18573.1 - 1.8e-07 30.7 15.3 2.7e-07 30.1 15.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 GAM18573.1 - 0.00024 20.3 19.7 0.00032 19.9 19.7 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DHHC PF01529.20 GAM18573.1 - 0.0083 16.2 4.9 0.0083 16.2 4.9 2.9 2 1 1 3 3 3 1 DHHC palmitoyltransferase Yip1 PF04893.17 GAM18573.1 - 0.017 14.8 8.4 5.1 6.8 9.2 2.4 1 1 1 2 2 2 0 Yip1 domain RICTOR_phospho PF14665.6 GAM18573.1 - 0.09 13.1 2.0 0.18 12.1 2.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site MscS_TM PF12794.7 GAM18573.1 - 0.098 11.5 3.4 0.17 10.7 3.4 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF3671 PF12420.8 GAM18573.1 - 5.4 7.1 10.5 0.99 9.5 2.6 2.9 3 0 0 3 3 3 0 Protein of unknown function LRR_4 PF12799.7 GAM18574.1 - 0.0013 19.1 28.3 1.3 9.5 0.2 6.8 3 3 6 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM18574.1 - 0.0053 16.5 16.3 2.6 7.9 0.2 5.4 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.6 GAM18574.1 - 0.0059 16.6 6.4 1.9 8.8 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich repeat DUF4419 PF14388.6 GAM18574.1 - 0.14 11.6 0.5 0.2 11.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) LRR_1 PF00560.33 GAM18574.1 - 5.7 7.9 20.3 1.7 9.5 0.2 6.0 6 1 0 6 6 6 0 Leucine Rich Repeat CLU PF13236.6 GAM18575.1 - 6.2e-59 199.5 0.0 3.9e-58 196.9 0.0 2.3 3 0 0 3 3 3 1 Clustered mitochondria eIF3_p135 PF12807.7 GAM18575.1 - 4.4e-10 39.9 0.1 4.4e-10 39.9 0.1 2.8 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TruB_N PF01509.18 GAM18575.1 - 0.074 13.4 1.8 0.2 12.0 1.8 1.6 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) FliP PF00813.20 GAM18575.1 - 3 7.7 5.8 3.5 7.5 0.3 2.4 2 0 0 2 2 2 0 FliP family CLU PF13236.6 GAM18576.1 - 9.2e-59 198.9 0.0 1.5e-58 198.3 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAM18576.1 - 4.4e-07 30.1 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 LRR_1 PF00560.33 GAM18576.1 - 0.0077 16.6 4.1 0.6 10.9 0.0 5.5 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.7 GAM18576.1 - 3.2 8.3 18.9 12 6.5 0.3 7.1 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) TBPIP PF07106.13 GAM18577.1 - 1.2e-12 47.5 0.1 2.2e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 GAM18577.1 - 5.5e-10 39.2 0.9 5.5e-10 39.2 0.9 2.2 2 1 1 3 3 2 1 Leucine zipper with capping helix domain Troponin PF00992.20 GAM18577.1 - 0.011 16.1 9.8 0.011 16.1 9.8 1.8 1 1 1 2 2 2 0 Troponin DUF4250 PF14056.6 GAM18577.1 - 0.03 14.3 2.0 0.079 12.9 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4250) Cnn_1N PF07989.11 GAM18577.1 - 0.043 14.0 6.8 0.095 12.9 0.2 2.7 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 NPV_P10 PF05531.12 GAM18577.1 - 0.055 13.9 3.4 0.13 12.7 3.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 GAM18577.1 - 0.06 12.7 7.6 0.079 12.3 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) JIP_LZII PF16471.5 GAM18577.1 - 0.099 12.8 0.6 0.099 12.8 0.6 2.8 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF919 PF06034.11 GAM18577.1 - 0.15 11.9 2.3 0.39 10.6 2.3 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Mnd1 PF03962.15 GAM18577.1 - 0.21 11.9 1.4 0.55 10.6 0.0 2.2 2 0 0 2 2 2 0 Mnd1 HTH domain APG6_N PF17675.1 GAM18577.1 - 0.28 11.7 21.5 0.28 11.7 5.5 2.6 1 1 2 3 3 3 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 GAM18577.1 - 0.29 11.4 17.6 0.096 12.9 9.6 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 GAM18577.1 - 0.33 10.1 4.0 0.49 9.6 4.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 GAM18577.1 - 0.4 9.2 7.2 0.55 8.8 7.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A GREB1 PF15782.5 GAM18577.1 - 0.55 7.3 7.9 0.64 7.1 7.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1319 PF07028.11 GAM18577.1 - 0.97 9.7 9.0 2.8 8.2 0.8 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1319) DivIC PF04977.15 GAM18577.1 - 1.2 9.0 14.7 0.1 12.4 7.8 2.6 2 1 1 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 GAM18577.1 - 1.2 9.2 14.8 1.7 8.7 14.2 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 GAM18577.1 - 1.4 9.1 17.4 1.6 8.9 13.3 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 YabA PF06156.13 GAM18577.1 - 1.7 9.3 8.7 13 6.4 0.5 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Phage_GP20 PF06810.11 GAM18577.1 - 1.7 8.4 14.6 0.4 10.5 10.7 2.0 2 1 0 2 2 1 0 Phage minor structural protein GP20 ABC_tran_CTD PF16326.5 GAM18577.1 - 1.8 8.9 13.0 2.1 8.6 8.9 2.7 2 1 1 3 3 3 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 GAM18577.1 - 1.8 8.7 8.4 3.8 7.7 8.4 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 GAM18577.1 - 2.1 6.2 5.3 2.4 5.9 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaG PF03646.15 GAM18577.1 - 2.6 8.3 9.0 4.3 7.6 0.5 2.5 1 1 1 2 2 2 0 FlaG protein ADIP PF11559.8 GAM18577.1 - 4 7.5 17.4 21 5.2 17.5 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Selenoprotein_S PF06936.11 GAM18577.1 - 4.5 7.0 15.3 2.6 7.8 6.4 2.2 1 1 1 2 2 2 0 Selenoprotein S (SelS) Spc24 PF08286.11 GAM18577.1 - 6 7.2 13.2 32 4.8 13.2 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Ax_dynein_light PF10211.9 GAM18577.1 - 9.1 6.2 14.0 7.5 6.5 2.1 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain SNAP PF14938.6 GAM18578.1 - 2.8e-15 56.5 12.6 4.6e-15 55.8 12.6 1.3 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP Beta-lactamase PF00144.24 GAM18579.1 - 2.6e-43 148.5 0.0 3.2e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 GAM18579.1 - 0.16 11.4 0.0 0.99 8.8 0.0 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Abhydrolase_1 PF00561.20 GAM18580.1 - 1.1e-11 44.9 0.2 2e-11 44.0 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM18580.1 - 5.5e-08 33.7 0.0 7.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM18580.1 - 1.2e-07 31.2 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 GAM18580.1 - 0.00024 20.4 0.1 0.00037 19.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) PGAP1 PF07819.13 GAM18580.1 - 0.025 14.3 0.1 0.049 13.3 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S28 PF05577.12 GAM18580.1 - 0.087 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 GAM18580.1 - 0.18 10.4 0.0 0.37 9.4 0.0 1.4 1 0 0 1 1 1 0 PS-10 peptidase S37 Dicty_CTDC PF00526.18 GAM18581.1 - 2.2e-31 107.4 137.9 3.1e-09 36.6 6.5 10.9 11 0 0 11 11 11 9 Dictyostelium (slime mold) repeat SARAF PF06682.12 GAM18582.1 - 4.5e-68 230.3 6.2 5.1e-68 230.2 2.4 2.0 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis Orf78 PF06024.12 GAM18582.1 - 0.022 15.0 0.3 0.49 10.7 0.3 2.2 2 0 0 2 2 2 0 Orf78 (ac78) DUF2615 PF11027.8 GAM18582.1 - 0.1 12.7 1.7 1.2 9.3 0.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2615) FixQ PF05545.11 GAM18582.1 - 0.47 10.5 1.7 0.82 9.7 0.0 2.1 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ CRA PF06589.11 GAM18582.1 - 4.1 7.5 5.5 18 5.4 0.0 2.3 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) SH3_19 PF18597.1 GAM18583.1 - 0.1 12.5 0.2 0.23 11.3 0.2 1.6 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain LRR_4 PF12799.7 GAM18583.1 - 0.15 12.6 4.3 3.3 8.3 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) PP2C PF00481.21 GAM18584.1 - 2.3e-35 122.5 0.1 2.3e-35 122.5 0.1 1.9 1 1 1 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAM18584.1 - 1.3e-10 41.3 0.1 3.9e-10 39.7 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Zip PF02535.22 GAM18584.1 - 0.39 9.9 11.6 0.56 9.4 11.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.16 GAM18584.1 - 1.2 8.4 9.0 1.8 7.8 9.0 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.14 GAM18584.1 - 3.3 7.0 27.1 6.8 6.0 27.1 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 GAM18584.1 - 6.4 5.2 7.3 9.7 4.6 7.3 1.2 1 0 0 1 1 1 0 Macoilin family Vps23_core PF09454.10 GAM18585.1 - 3.9e-26 90.8 0.1 3.9e-26 90.8 0.1 3.2 4 0 0 4 4 4 1 Vps23 core domain UEV PF05743.13 GAM18585.1 - 4.1e-25 88.0 0.7 4.1e-25 88.0 0.7 2.0 2 0 0 2 2 2 1 UEV domain ANAPC_CDC26 PF10471.9 GAM18585.1 - 0.028 15.2 3.2 0.028 15.2 3.2 5.5 4 2 0 4 4 4 0 Anaphase-promoting complex APC subunit CDC26 LAGLIDADG_1 PF00961.19 GAM18585.1 - 4.4 8.3 0.0 4.4 8.3 0.0 3.9 4 1 0 4 4 4 0 LAGLIDADG endonuclease DUF948 PF06103.11 GAM18585.1 - 9.8 6.5 7.8 1 9.7 0.3 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GLTSCR1 PF15249.6 GAM18586.1 - 0.00041 20.7 5.1 0.00041 20.7 5.1 3.6 3 1 1 4 4 4 1 Conserved region of unknown function on GLTSCR protein DENN PF02141.21 GAM18587.1 - 2e-26 93.1 5.3 1.7e-24 86.8 5.3 2.5 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAM18587.1 - 8.1e-07 29.7 2.5 2.1e-06 28.4 2.5 1.7 1 0 0 1 1 1 1 uDENN domain SPA PF08616.10 GAM18587.1 - 0.0029 17.6 0.2 0.0072 16.3 0.2 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis dDENN PF03455.19 GAM18587.1 - 0.013 15.5 0.3 0.056 13.4 0.1 2.2 2 0 0 2 2 2 0 dDENN domain L_HMGIC_fpl PF10242.9 GAM18587.1 - 0.47 10.6 2.0 0.79 9.9 2.0 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Pro_isomerase PF00160.21 GAM18588.1 - 4.1e-12 46.7 0.0 5.2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 GAM18589.1 - 1.6e-74 250.6 0.0 2.8e-74 249.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18589.1 - 3e-44 151.3 0.0 4.7e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 GAM18589.1 - 8e-06 25.7 0.0 1.2 9.5 0.0 4.6 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 GAM18589.1 - 2.7e-05 24.6 2.2 0.56 10.8 0.0 4.4 4 0 0 4 4 4 2 HEAT-like repeat FTA2 PF13095.6 GAM18589.1 - 5.3e-05 23.0 0.2 0.00073 19.2 0.1 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 GAM18589.1 - 8.2e-05 21.5 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Arm PF00514.23 GAM18589.1 - 0.00071 19.5 0.0 15 5.8 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAM18589.1 - 0.0017 18.7 0.0 0.025 15.0 0.0 3.0 2 1 0 2 2 2 1 HEAT repeats Kinase-like PF14531.6 GAM18589.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GAM18589.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NTP_transferase PF00483.23 GAM18590.1 - 2.6e-51 174.6 0.0 3.4e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 GAM18590.1 - 2.7e-10 39.6 5.6 2.4e-06 27.0 0.2 3.9 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAM18590.1 - 2.3e-09 37.8 0.0 2.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 GAM18590.1 - 0.0091 14.2 0.2 0.017 13.3 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) DUF257 PF03192.13 GAM18590.1 - 0.031 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Hexapep_2 PF14602.6 GAM18590.1 - 0.21 11.3 5.7 4.1 7.2 0.4 4.2 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase RNA12 PF10443.9 GAM18591.1 - 1.1e-51 176.0 0.0 6.8e-27 94.3 0.0 3.1 1 1 1 2 2 2 2 RNA12 protein RRM_1 PF00076.22 GAM18591.1 - 1.2e-05 25.1 0.0 4.5e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_35 PF14516.6 GAM18591.1 - 0.014 14.2 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ATPase_2 PF01637.18 GAM18591.1 - 0.019 14.9 0.0 0.05 13.5 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GAM18591.1 - 0.045 14.1 0.0 0.31 11.4 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 GAM18591.1 - 0.093 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DJ-1_PfpI PF01965.24 GAM18592.1 - 2.9e-42 144.3 0.1 3.4e-42 144.0 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAM18592.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 1 0 1 1 1 0 ThiJ/PfpI family-like Nop PF01798.18 GAM18593.1 - 1.1e-87 293.3 0.9 1.1e-87 293.3 0.9 2.8 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin Borrelia_P83 PF05262.11 GAM18593.1 - 0.076 11.5 40.2 3.1 6.2 40.2 2.2 1 1 0 1 1 1 0 Borrelia P83/100 protein NOP5NT PF08156.13 GAM18594.1 - 5.4e-18 65.1 0.1 1e-17 64.3 0.1 1.5 1 0 0 1 1 1 1 NOP5NT (NUC127) domain G-alpha PF00503.20 GAM18595.1 - 3.4e-109 365.3 6.2 5.8e-109 364.5 6.2 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM18595.1 - 6.7e-15 55.0 0.8 2e-11 43.7 0.2 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM18595.1 - 2.1e-06 27.3 1.0 0.0006 19.2 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM18595.1 - 7.7e-06 26.1 0.1 0.02 15.1 0.1 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase LolA PF03548.15 GAM18595.1 - 0.028 14.1 0.6 0.076 12.7 0.1 2.0 3 1 0 3 3 3 0 Outer membrane lipoprotein carrier protein LolA MMR_HSR1 PF01926.23 GAM18595.1 - 0.054 13.6 0.0 3.5 7.8 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM18595.1 - 0.089 12.3 0.0 0.67 9.5 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Epimerase PF01370.21 GAM18595.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAA_29 PF13555.6 GAM18595.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CBS PF00571.28 GAM18597.1 - 2e-24 85.8 0.1 4e-08 33.6 0.0 4.2 4 0 0 4 4 4 4 CBS domain Pkinase PF00069.25 GAM18598.1 - 2.2e-70 237.1 0.0 2.8e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18598.1 - 3.6e-40 137.9 0.0 4.7e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM18598.1 - 1.4e-06 27.9 0.0 3e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAM18598.1 - 7.9e-06 26.0 0.1 0.091 12.7 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM18598.1 - 0.0001 21.4 0.1 0.0001 21.4 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 GAM18598.1 - 0.00023 20.6 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GAM18598.1 - 0.0015 18.2 2.4 0.0039 16.8 0.8 2.0 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 GAM18598.1 - 0.049 13.2 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Sulfotransfer_2 PF03567.14 GAM18599.1 - 9e-13 48.7 0.1 1.9e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 GAM18599.1 - 0.00012 21.1 0.2 0.00031 19.8 0.2 1.7 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase 7tm_3 PF00003.22 GAM18600.1 - 8.1e-45 153.4 20.4 1.5e-44 152.5 20.4 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 GAM18600.1 - 9.8e-19 67.4 0.1 1.4e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Borrelia_P13 PF05628.12 GAM18600.1 - 0.064 13.2 0.6 0.95 9.4 0.0 2.8 2 0 0 2 2 2 0 Borrelia membrane protein P13 Transglut_core PF01841.19 GAM18601.1 - 4.6e-11 43.2 0.0 8.9e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Peptidase_C71 PF12386.8 GAM18601.1 - 0.037 13.7 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei PCI PF01399.27 GAM18602.1 - 4.9e-06 27.0 0.5 8.5e-06 26.2 0.5 1.4 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 GAM18602.1 - 0.015 15.2 0.1 0.041 13.8 0.1 1.8 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain CtsR PF05848.11 GAM18602.1 - 0.088 12.7 0.1 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 CtsR N-terminal HTH domain WD40 PF00400.32 GAM18603.1 - 1.9e-32 110.7 14.3 3.8e-07 30.7 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM18603.1 - 1.5e-07 31.6 1.2 3.6 7.9 0.0 5.1 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM18603.1 - 7.1e-06 25.6 3.3 0.00021 20.8 1.0 2.7 1 1 1 3 3 3 1 WD40-like domain PQQ_2 PF13360.6 GAM18603.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.6 1 1 0 1 1 1 0 PQQ-like domain DUF5046 PF16465.5 GAM18603.1 - 0.03 13.8 0.8 0.7 9.3 0.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) Nucleoporin_N PF08801.11 GAM18603.1 - 0.043 12.6 4.2 2.4 6.8 0.1 3.2 1 1 2 3 3 3 0 Nup133 N terminal like Mon2_C PF16206.5 GAM18604.1 - 5.7e-68 229.8 6.6 6e-47 160.3 0.5 3.3 2 1 0 2 2 2 2 C-terminal region of Mon2 protein DCB PF16213.5 GAM18604.1 - 3.9e-52 176.5 6.5 3.9e-52 176.5 6.5 4.0 5 0 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 GAM18604.1 - 5.2e-37 127.2 7.8 7.1e-35 120.2 0.7 3.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAM18604.1 - 2.9e-11 43.1 6.5 1.2e-10 41.1 0.5 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Calreticulin PF00262.18 GAM18605.1 - 7.7e-143 475.8 6.9 1.1e-142 475.3 6.9 1.2 1 0 0 1 1 1 1 Calreticulin family FAM176 PF14851.6 GAM18605.1 - 0.0061 16.2 2.7 0.0067 16.1 0.1 2.3 1 1 1 2 2 2 1 FAM176 family DUF883 PF05957.13 GAM18605.1 - 0.025 15.2 0.0 0.057 14.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) LMBR1 PF04791.16 GAM18606.1 - 2.8e-133 445.5 27.2 3.3e-133 445.3 27.2 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Thioredoxin PF00085.20 GAM18607.1 - 6.5e-25 87.1 0.0 8e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAM18607.1 - 1.6e-07 31.7 0.0 7.4e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAM18607.1 - 2.8e-06 27.6 0.0 0.0005 20.4 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 GAM18607.1 - 3e-05 24.1 0.0 6e-05 23.1 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 GAM18607.1 - 3.1e-05 23.8 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 GAM18607.1 - 0.0028 17.5 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 GAM18607.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain DUF4203 PF13886.6 GAM18608.1 - 3e-06 27.0 29.7 4.2e-06 26.6 29.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) AAA PF00004.29 GAM18609.1 - 2.3e-98 325.7 0.0 2e-48 164.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM18609.1 - 9.9e-26 89.3 4.5 1.3e-12 47.3 0.2 3.4 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 GAM18609.1 - 7.5e-20 70.9 0.3 2.1e-19 69.5 0.3 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 GAM18609.1 - 5.8e-15 55.4 0.0 3.1e-06 27.0 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAM18609.1 - 2.9e-13 50.3 0.0 4.9e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAM18609.1 - 1.3e-12 48.5 0.2 0.00035 21.0 0.0 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 GAM18609.1 - 1.1e-11 45.1 0.0 1.3e-05 25.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 GAM18609.1 - 1.9e-11 44.1 0.1 1.1e-05 25.4 0.0 3.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM18609.1 - 4.1e-10 40.1 0.3 0.0069 16.7 0.1 4.0 2 2 1 3 3 3 2 AAA domain CDC48_2 PF02933.17 GAM18609.1 - 7.4e-10 38.5 0.0 1.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 GAM18609.1 - 1.3e-09 38.1 0.0 0.00023 21.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.13 GAM18609.1 - 3.3e-08 33.1 0.2 0.0017 17.6 0.0 2.6 3 0 0 3 3 2 2 TIP49 P-loop domain Vps4_C PF09336.10 GAM18609.1 - 4.3e-08 33.0 0.2 6.7e-06 26.0 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 GAM18609.1 - 9e-08 32.5 0.0 0.0089 16.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 GAM18609.1 - 9.1e-08 32.7 0.0 0.015 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GAM18609.1 - 9.6e-08 31.7 0.3 0.0096 15.3 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 GAM18609.1 - 9.5e-07 29.0 0.1 0.074 13.0 0.0 3.2 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 GAM18609.1 - 1.1e-06 28.6 0.0 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 GAM18609.1 - 1.3e-06 28.3 0.1 0.042 13.6 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein Bac_DnaA PF00308.18 GAM18609.1 - 2.2e-06 27.7 0.0 0.013 15.4 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_28 PF13521.6 GAM18609.1 - 2.5e-06 27.8 0.0 0.13 12.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 GAM18609.1 - 2.6e-06 28.0 0.0 0.022 15.2 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Parvo_NS1 PF01057.17 GAM18609.1 - 4.8e-06 25.9 0.1 0.029 13.5 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 GAM18609.1 - 5.7e-06 26.0 1.5 0.97 9.0 0.0 3.9 2 2 0 4 4 4 1 AAA domain AAA_7 PF12775.7 GAM18609.1 - 9.2e-06 25.3 0.0 0.11 12.0 0.0 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 GAM18609.1 - 1.2e-05 25.8 0.0 0.13 12.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GAM18609.1 - 1.2e-05 25.3 0.1 0.23 11.4 0.0 3.2 3 1 1 4 4 2 2 NACHT domain Rad17 PF03215.15 GAM18609.1 - 1.6e-05 25.0 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain TsaE PF02367.17 GAM18609.1 - 2.1e-05 24.5 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 GAM18609.1 - 2.1e-05 23.9 0.0 0.097 11.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin ATPase PF06745.13 GAM18609.1 - 2.3e-05 23.9 0.1 2.8 7.2 0.0 3.4 3 0 0 3 3 3 1 KaiC AAA_24 PF13479.6 GAM18609.1 - 4.9e-05 23.1 0.0 0.089 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 GAM18609.1 - 6.5e-05 22.2 0.0 0.24 10.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.26 GAM18609.1 - 7.9e-05 22.4 0.0 1 9.1 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 GAM18609.1 - 0.00019 20.7 0.0 0.15 11.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 GAM18609.1 - 0.00025 21.1 0.0 0.66 10.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 GAM18609.1 - 0.00034 20.8 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_3 PF07726.11 GAM18609.1 - 0.00064 19.6 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 GAM18609.1 - 0.00076 19.5 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 GAM18609.1 - 0.0035 17.3 0.2 3.1 7.7 0.0 3.5 3 0 0 3 3 3 1 NTPase TniB PF05621.11 GAM18609.1 - 0.0054 16.2 0.0 1.8 8.0 0.0 3.7 3 1 1 4 4 4 1 Bacterial TniB protein PhoH PF02562.16 GAM18609.1 - 0.0054 16.2 0.3 1.8 8.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.6 GAM18609.1 - 0.0081 16.5 1.0 7.1 7.0 0.1 3.3 3 1 1 4 4 2 0 AAA domain SKI PF01202.22 GAM18609.1 - 0.0085 16.2 0.0 6 7.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase PduV-EutP PF10662.9 GAM18609.1 - 0.01 15.6 0.0 3.2 7.5 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.6 GAM18609.1 - 0.011 15.6 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAM18609.1 - 0.015 14.5 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 GAM18609.1 - 0.026 15.0 0.0 12 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain UFD1 PF03152.14 GAM18609.1 - 0.033 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 KAP_NTPase PF07693.14 GAM18609.1 - 0.045 13.0 0.1 2.4 7.3 0.0 3.0 2 2 2 4 4 3 0 KAP family P-loop domain AFG1_ATPase PF03969.16 GAM18609.1 - 0.05 12.5 0.5 5.3 5.8 0.0 2.5 3 0 0 3 3 3 0 AFG1-like ATPase Cytidylate_kin PF02224.18 GAM18609.1 - 0.068 12.9 0.0 15 5.2 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Adeno_IVa2 PF02456.15 GAM18609.1 - 0.079 11.7 0.0 10 4.8 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.6 GAM18609.1 - 0.093 12.4 0.0 18 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.11 GAM18609.1 - 0.12 12.4 0.0 0.81 9.8 0.0 2.3 2 0 0 2 2 2 0 tRNA ligase kinase domain Hid1 PF12722.7 GAM18610.1 - 1.5e-139 466.6 26.8 1.5e-139 466.6 26.8 3.1 2 1 0 2 2 2 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 GAM18610.1 - 2.1e-134 449.3 13.6 2.7e-134 448.9 13.6 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF913 PF06025.12 GAM18610.1 - 0.00044 19.3 1.5 0.00044 19.3 1.5 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) RcsC PF09456.10 GAM18610.1 - 0.021 14.8 0.2 0.2 11.7 0.0 2.8 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) DAG_kinase_N PF14513.6 GAM18610.1 - 0.033 14.4 0.1 0.033 14.4 0.1 3.4 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus TFCD_C PF12612.8 GAM18610.1 - 0.12 12.2 1.5 7.4 6.4 0.1 3.2 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal CCDC53 PF10152.9 GAM18610.1 - 0.12 12.8 19.4 1 9.8 2.2 3.6 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Mem_trans PF03547.18 GAM18610.1 - 2.5 6.4 7.4 0.18 10.2 1.0 2.2 2 0 0 2 2 2 0 Membrane transport protein CBS PF00571.28 GAM18612.1 - 9.8e-23 80.4 4.2 1.1e-07 32.2 0.0 4.4 4 0 0 4 4 4 4 CBS domain Proteasom_PSMB PF10508.9 GAM18614.1 - 1.8e-24 86.1 0.1 2.1e-15 56.2 0.0 2.1 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit IPP-2 PF04979.14 GAM18615.1 - 4.8e-20 72.6 25.9 4.8e-20 72.6 25.9 3.8 2 2 1 3 3 3 1 Protein phosphatase inhibitor 2 (IPP-2) DHHC PF01529.20 GAM18616.1 - 1.8e-32 112.3 6.6 1.8e-32 112.3 6.6 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Rab5ip PF07019.12 GAM18616.1 - 0.018 15.6 2.7 0.073 13.7 0.6 2.5 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Cadherin_C_2 PF16492.5 GAM18616.1 - 0.15 12.8 2.2 6 7.7 1.0 2.8 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Transket_pyr PF02779.24 GAM18617.1 - 9.2e-57 191.6 0.0 1.4e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 GAM18617.1 - 1.9e-48 164.0 0.0 3.6e-48 163.1 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 GAM18617.1 - 5.3e-47 160.2 0.0 9.2e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component YhfZ_C PF14503.6 GAM18617.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 YhfZ C-terminal domain EF-hand_like PF09279.11 GAM18617.1 - 1.1 9.7 4.0 0.41 11.2 0.3 2.2 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like RabGAP-TBC PF00566.18 GAM18618.1 - 1.9e-57 194.4 1.5 2.8e-57 193.8 1.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Collar PF07484.12 GAM18618.1 - 0.074 13.1 0.0 2 8.5 0.0 2.6 2 0 0 2 2 2 0 Phage Tail Collar Domain YL1_C PF08265.11 GAM18619.1 - 3.3e-13 49.1 1.9 7.2e-13 48.1 1.5 1.8 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Myc_N PF01056.18 GAM18619.1 - 2.1 8.1 17.2 0.18 11.7 5.9 2.1 1 1 1 2 2 2 0 Myc amino-terminal region Ndc1_Nup PF09531.10 GAM18619.1 - 7.1 5.2 9.0 8.9 4.9 9.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BUD22 PF09073.10 GAM18620.1 - 0.11 11.8 26.7 0.14 11.4 26.7 1.1 1 0 0 1 1 1 0 BUD22 VHS PF00790.19 GAM18621.1 - 3.6e-23 82.0 0.2 7.6e-23 80.9 0.2 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 GAM18621.1 - 6.9e-13 48.7 1.6 1.7e-12 47.4 1.6 1.7 1 0 0 1 1 1 1 GAT domain Rhomboid PF01694.22 GAM18622.1 - 6.5e-22 78.1 14.6 1.2e-21 77.3 14.6 1.4 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 GAM18622.1 - 1.5e-08 34.8 16.4 2.4e-08 34.2 16.4 1.3 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.10 GAM18622.1 - 0.0087 16.6 2.8 0.0087 16.6 2.8 2.2 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Ribosomal_S17e PF00833.18 GAM18623.1 - 5.2e-58 194.3 0.4 6.3e-58 194.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 MFS_1 PF07690.16 GAM18624.1 - 6.6e-19 68.0 44.1 6.6e-19 68.0 44.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM18624.1 - 7.8e-09 34.6 30.3 7.8e-09 34.6 30.3 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 GAM18624.1 - 2.5e-05 23.5 19.7 0.0025 16.9 3.8 3.3 2 1 0 3 3 3 3 PUCC protein Pkinase PF00069.25 GAM18625.1 - 9.2e-74 248.1 0.7 9.8e-74 248.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18625.1 - 1.2e-35 123.1 0.0 2e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAM18625.1 - 6.3e-05 23.6 0.2 6.3e-05 23.6 0.2 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 GAM18625.1 - 0.00076 18.9 0.0 0.00076 18.9 0.0 2.5 3 0 0 3 3 2 1 Kinase-like Pkinase_fungal PF17667.1 GAM18625.1 - 0.005 15.7 9.1 0.043 12.6 9.1 2.0 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAM18625.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM18625.1 - 0.02 13.8 3.7 0.038 12.9 3.5 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Ndc1_Nup PF09531.10 GAM18625.1 - 0.021 13.5 6.0 0.023 13.4 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FTA2 PF13095.6 GAM18625.1 - 0.037 13.7 7.5 0.39 10.3 0.2 2.9 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pex14_N PF04695.13 GAM18625.1 - 0.15 12.7 11.6 0.27 11.9 11.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hamartin PF04388.12 GAM18625.1 - 0.54 8.9 10.1 0.73 8.4 10.1 1.1 1 0 0 1 1 1 0 Hamartin protein Suf PF05843.14 GAM18625.1 - 9.8 6.1 13.0 14 5.5 13.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) WD40 PF00400.32 GAM18626.1 - 1.3e-49 165.1 30.7 1.6e-09 38.2 0.1 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM18626.1 - 1.4e-26 92.6 1.8 2.9e-07 30.7 0.0 7.1 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 GAM18626.1 - 2.6e-09 36.7 0.3 6.4e-09 35.5 0.3 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 GAM18626.1 - 6.7e-09 35.9 4.1 0.00037 20.4 0.1 4.0 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAM18626.1 - 0.0002 20.8 0.0 0.36 10.1 0.0 3.4 2 1 1 4 4 4 2 WD40-like domain Nbas_N PF15492.6 GAM18626.1 - 0.01 15.2 0.4 1.9 7.8 0.0 3.1 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 GAM18626.1 - 0.04 13.2 0.0 0.23 10.7 0.0 2.2 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FcoT PF10862.8 GAM18626.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 FcoT-like thioesterase domain IHABP4_N PF16174.5 GAM18626.1 - 0.77 10.3 8.1 1.2 9.8 8.1 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Sec62 PF03839.16 GAM18626.1 - 2 7.9 8.1 3.2 7.2 8.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Pkinase PF00069.25 GAM18627.1 - 4.8e-78 262.2 0.0 6.2e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18627.1 - 1.6e-37 129.2 0.0 2.2e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCHH PF10283.9 GAM18627.1 - 3.5e-13 49.2 3.4 7.5e-13 48.2 3.4 1.6 1 0 0 1 1 1 1 PBZ domain FHA PF00498.26 GAM18627.1 - 1.2e-11 44.8 0.5 2.4e-11 43.8 0.1 1.8 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 GAM18627.1 - 1.8e-09 37.3 0.0 2.9e-07 30.1 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 GAM18627.1 - 3.3e-08 33.1 0.1 5.1e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM18627.1 - 1.5e-05 23.9 0.0 6.8e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 GAM18627.1 - 0.00087 18.9 0.2 0.0017 17.9 0.2 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Yop-YscD_cpl PF16697.5 GAM18627.1 - 0.0024 18.1 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RIO1 PF01163.22 GAM18627.1 - 0.0063 16.1 0.2 0.011 15.4 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 GAM18627.1 - 0.0088 15.0 0.5 0.013 14.4 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM18627.1 - 0.031 14.2 0.0 1.2 9.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FHA_2 PF17913.1 GAM18627.1 - 0.047 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 FHA domain Ank_2 PF12796.7 GAM18628.1 - 0.0012 19.3 0.3 0.4 11.3 0.1 3.7 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM18628.1 - 0.042 14.2 0.1 6.8 7.1 0.0 3.8 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM18628.1 - 0.97 10.2 4.2 12 6.9 0.0 4.5 5 1 0 5 5 5 0 Ankyrin repeat CBS PF00571.28 GAM18631.1 - 3.3e-28 97.9 5.4 7.5e-10 39.1 0.0 4.5 4 0 0 4 4 4 4 CBS domain DENN PF02141.21 GAM18632.1 - 5.3e-50 170.0 8.2 5.3e-50 170.0 8.2 2.4 3 0 0 3 3 3 1 DENN (AEX-3) domain WD40 PF00400.32 GAM18632.1 - 2e-40 136.0 32.8 8.6e-06 26.4 0.4 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat uDENN PF03456.18 GAM18632.1 - 7.6e-17 61.8 0.4 2.5e-16 60.1 0.4 2.0 1 0 0 1 1 1 1 uDENN domain C2 PF00168.30 GAM18632.1 - 4.4e-11 43.0 1.3 1.6e-10 41.2 1.3 1.9 1 0 0 1 1 1 1 C2 domain SBF2 PF12335.8 GAM18632.1 - 1.4e-06 28.1 1.0 1.4e-06 28.1 1.0 2.7 3 0 0 3 3 3 1 Myotubularin protein dDENN PF03455.19 GAM18632.1 - 1.7e-05 24.7 0.6 4.3e-05 23.4 0.6 1.8 1 0 0 1 1 1 1 dDENN domain Nup160 PF11715.8 GAM18632.1 - 6.5e-05 21.8 9.6 0.17 10.5 0.1 4.6 2 2 1 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAM18632.1 - 0.0011 19.3 2.6 5.7 7.3 0.1 4.9 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM18632.1 - 0.0078 15.6 4.0 2.2 7.5 0.1 3.4 2 1 0 3 3 3 2 WD40-like domain JAB PF01398.21 GAM18633.1 - 8.7e-34 116.0 0.3 2.2e-33 114.7 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GAM18633.1 - 1.8e-09 38.0 0.7 3.8e-09 36.9 0.7 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 GAM18633.1 - 4.4e-08 32.9 0.0 7.8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain G6PD_bact PF10786.9 GAM18633.1 - 0.0021 17.6 0.8 0.003 17.1 0.8 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) DUF2141 PF09912.9 GAM18633.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Methyltransf_16 PF10294.9 GAM18634.1 - 6.8e-20 71.5 0.2 1.2e-19 70.7 0.2 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 GAM18634.1 - 0.003 18.2 0.2 0.022 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM18634.1 - 0.0061 16.4 0.1 0.013 15.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 GAM18634.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 GAM18634.1 - 0.083 13.5 0.2 0.39 11.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PH PF00169.29 GAM18635.1 - 3.1e-26 91.9 0.0 1.9e-13 50.8 0.0 2.7 2 0 0 2 2 2 2 PH domain TPR_19 PF14559.6 GAM18635.1 - 6.2e-12 45.9 0.3 0.0011 19.4 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM18635.1 - 3.3e-10 39.3 2.6 0.26 11.5 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat C2 PF00168.30 GAM18635.1 - 1.4e-07 31.7 0.2 6.6e-07 29.6 0.1 2.2 2 1 0 2 2 2 1 C2 domain TPR_11 PF13414.6 GAM18635.1 - 1.7e-06 27.6 1.1 0.077 12.7 0.1 3.1 3 0 0 3 3 3 2 TPR repeat PH_3 PF14593.6 GAM18635.1 - 2.7e-06 27.4 1.2 3.6e-05 23.8 0.4 2.9 2 1 0 2 2 2 1 PH domain TPR_1 PF00515.28 GAM18635.1 - 6.6e-06 25.7 6.9 0.58 10.1 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM18635.1 - 1.1e-05 26.0 0.0 0.12 13.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat PH_6 PF15406.6 GAM18635.1 - 4.9e-05 23.6 0.0 0.003 17.8 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain TPR_8 PF13181.6 GAM18635.1 - 8.6e-05 22.5 3.1 3.1 8.2 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM18635.1 - 0.0057 17.4 0.0 55 5.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM18635.1 - 0.0062 16.7 2.2 0.053 13.8 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PH_11 PF15413.6 GAM18635.1 - 0.087 13.3 10.6 1.4 9.4 0.5 4.2 3 2 0 4 4 4 0 Pleckstrin homology domain Auxin_repressed PF05564.12 GAM18635.1 - 4.8 7.9 5.6 45 4.8 0.5 3.4 4 0 0 4 4 3 0 Dormancy/auxin associated protein Ribosomal_S7 PF00177.21 GAM18636.1 - 2.2e-34 118.3 0.8 2.7e-34 118.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ank_2 PF12796.7 GAM18637.1 - 0.0022 18.5 0.0 41 4.8 0.0 4.7 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM18637.1 - 0.035 14.7 0.6 1e+02 4.0 0.1 5.2 6 0 0 6 6 6 0 Ankyrin repeat VPS13 PF16908.5 GAM18638.1 - 1.3e-65 221.5 21.4 5.4e-64 216.2 0.5 5.5 5 0 0 5 5 5 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 GAM18638.1 - 3.9e-59 199.4 10.7 2.7e-57 193.4 0.7 3.9 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 GAM18638.1 - 6.1e-58 196.0 16.6 2.6e-56 190.7 6.1 4.2 2 1 0 2 2 2 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 GAM18638.1 - 1.5e-45 155.7 8.7 6.7e-45 153.6 0.1 3.4 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 GAM18638.1 - 8.9e-38 129.0 1.9 6.5e-37 126.2 0.3 3.4 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 GAM18638.1 - 8.2e-11 42.1 1.3 8.6e-10 38.8 0.2 2.9 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chromo_2 PF18704.1 GAM18638.1 - 2 8.7 5.7 1 9.6 0.6 2.9 3 0 0 3 3 3 0 Chromatin organization modifier domain 2 HXXSHH PF07586.11 GAM18639.1 - 0.071 12.7 0.8 0.11 12.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) F-box-like PF12937.7 GAM18640.1 - 4.1e-06 26.6 0.1 4.1e-06 26.6 0.1 1.8 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 GAM18640.1 - 0.059 13.3 1.2 0.16 11.9 1.2 1.9 1 1 0 1 1 1 0 F-box PIP5K PF01504.18 GAM18641.1 - 3.9e-26 91.9 5.9 3.9e-26 91.9 5.9 3.6 2 2 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase SET PF00856.28 GAM18642.1 - 6.5e-12 46.2 0.9 2.6e-11 44.2 0.1 2.3 2 0 0 2 2 2 1 SET domain TPR_17 PF13431.6 GAM18642.1 - 0.00061 20.0 0.3 0.0019 18.5 0.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM18642.1 - 0.0022 17.7 0.9 0.0022 17.7 0.9 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat MTHFR_C PF12225.8 GAM18642.1 - 0.0023 17.5 3.9 0.0023 17.5 3.9 2.6 2 0 0 2 2 2 1 Methylene-tetrahydrofolate reductase C terminal TPR_2 PF07719.17 GAM18642.1 - 0.0027 17.7 7.6 0.0058 16.6 0.5 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM18642.1 - 0.0035 17.3 2.5 0.16 12.1 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM18642.1 - 0.012 15.9 3.1 0.016 15.4 1.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4542 PF15075.6 GAM18642.1 - 0.054 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) TPR_8 PF13181.6 GAM18642.1 - 0.078 13.2 0.2 0.078 13.2 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM18642.1 - 0.14 11.8 0.2 0.14 11.8 0.2 3.1 2 1 1 3 3 3 0 TPR repeat TPR_6 PF13174.6 GAM18642.1 - 0.17 12.6 3.6 0.31 11.8 1.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3797 PF12677.7 GAM18642.1 - 2.3 8.2 16.8 0.92 9.4 6.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) Cys_rich_KTR PF14205.6 GAM18642.1 - 2.5 8.0 8.8 17 5.3 1.9 3.4 3 0 0 3 3 3 0 Cysteine-rich KTR HTH_Tnp_4 PF13613.6 GAM18643.1 - 0.07 12.9 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease FTCD_N PF07837.12 GAM18645.1 - 3.8e-72 241.8 0.0 6.7e-72 241.0 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.14 GAM18645.1 - 1.8e-65 219.4 0.0 3.3e-65 218.5 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain FTCD_C PF04961.12 GAM18645.1 - 3.3e-65 219.3 0.5 5e-65 218.7 0.5 1.3 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase TIG PF01833.24 GAM18646.1 - 3.6e-09 36.6 9.8 6.2e-07 29.4 2.7 8.0 6 3 3 9 9 9 4 IPT/TIG domain MGC-24 PF05283.11 GAM18646.1 - 3.4 8.1 14.0 8.1 6.9 14.0 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF908 PF06012.12 GAM18646.1 - 4.3 6.7 7.3 9.2 5.6 7.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TMEM154 PF15102.6 GAM18646.1 - 8.2 6.3 9.5 16 5.4 9.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family Phage_integrase PF00589.22 GAM18648.1 - 0.00011 22.1 0.3 0.0081 16.0 0.0 2.3 2 0 0 2 2 2 2 Phage integrase family Phage_int_SAM_1 PF02899.17 GAM18648.1 - 0.00083 19.6 0.7 0.0022 18.3 0.1 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 GAM18648.1 - 0.018 15.5 0.7 0.059 13.8 0.1 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 GAM18648.1 - 0.086 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage integrase SAM-like domain Coatomer_WDAD PF04053.14 GAM18649.1 - 3.6e-10 39.5 3.7 0.42 9.6 0.0 5.3 5 1 0 5 5 5 4 Coatomer WD associated region WD40 PF00400.32 GAM18649.1 - 6.1e-06 26.9 0.6 0.05 14.5 0.0 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM18649.1 - 0.0044 17.3 0.1 8.7 6.7 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1478 PF07349.11 GAM18649.1 - 0.037 13.9 0.8 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1478) DUF2007 PF09413.10 GAM18651.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein CAP_GLY PF01302.25 GAM18653.1 - 1e-19 70.3 0.2 1.9e-19 69.4 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 GAM18653.1 - 1.1e-19 70.7 1.1 1.8e-19 70.0 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain YkuI_C PF10388.9 GAM18653.1 - 0.021 14.6 0.4 0.029 14.2 0.4 1.2 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain SpoU_methylase PF00588.19 GAM18654.1 - 5.4e-26 91.5 0.1 1.2e-25 90.3 0.1 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family ABC_transp_aux PF09822.9 GAM18654.1 - 0.047 13.2 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 ABC-type uncharacterized transport system TIG PF01833.24 GAM18655.1 - 1.8e-13 50.3 55.4 4.3e-06 26.7 6.6 7.1 5 2 2 7 7 7 5 IPT/TIG domain EGF_2 PF07974.13 GAM18655.1 - 0.017 15.5 9.7 0.041 14.2 9.7 1.7 1 0 0 1 1 1 0 EGF-like domain I-EGF_1 PF18372.1 GAM18657.1 - 0.00078 19.5 5.0 0.0023 18.0 5.0 1.8 1 0 0 1 1 1 1 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 GAM18657.1 - 0.0013 19.1 14.6 0.0027 18.0 14.6 1.6 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 GAM18657.1 - 0.0015 18.8 3.7 0.0032 17.7 3.7 1.5 1 0 0 1 1 1 1 EB module EGF_Tenascin PF18720.1 GAM18657.1 - 3.3 7.9 11.5 0.17 12.0 5.6 1.9 2 0 0 2 2 2 0 Tenascin EGF domain Metallophos PF00149.28 GAM18658.1 - 6.2e-14 53.0 2.5 9.7e-14 52.3 2.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ost5 PF05251.12 GAM18658.1 - 0.24 11.7 1.3 0.27 11.5 0.1 1.7 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 Pyr_redox_2 PF07992.14 GAM18659.1 - 1.7e-36 126.0 0.0 2.1e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM18659.1 - 2.4e-20 72.9 0.8 6e-13 49.2 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM18659.1 - 1.1e-08 35.1 0.0 0.016 14.8 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase DUF1188 PF06690.11 GAM18659.1 - 3.1e-07 30.2 0.2 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) K_oxygenase PF13434.6 GAM18659.1 - 4e-07 29.5 2.0 0.063 12.4 0.0 3.4 3 1 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAM18659.1 - 4.1e-06 26.9 0.0 0.013 15.7 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 GAM18659.1 - 5.4e-05 23.6 0.1 0.23 11.9 0.0 2.7 3 0 0 3 3 3 2 Putative NAD(P)-binding TrkA_N PF02254.18 GAM18659.1 - 6.2e-05 23.2 0.2 0.42 10.9 0.0 2.8 2 0 0 2 2 2 2 TrkA-N domain Lycopene_cycl PF05834.12 GAM18659.1 - 7.2e-05 22.0 0.0 0.15 11.1 0.0 2.5 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.14 GAM18659.1 - 0.00011 21.2 0.3 0.039 12.8 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FMO-like PF00743.19 GAM18659.1 - 0.00023 19.7 1.5 0.89 7.9 0.0 3.4 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Sacchrp_dh_NADP PF03435.18 GAM18659.1 - 0.00031 21.0 2.6 0.58 10.4 0.1 3.2 3 1 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain HI0933_like PF03486.14 GAM18659.1 - 0.00046 19.0 0.0 0.067 11.9 0.0 2.6 2 0 0 2 2 2 1 HI0933-like protein ApbA PF02558.16 GAM18659.1 - 0.0017 18.0 0.0 0.77 9.4 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 GAM18659.1 - 0.0018 18.3 3.1 0.37 10.8 0.0 4.0 2 2 2 4 4 4 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 GAM18659.1 - 0.002 18.0 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAM18659.1 - 0.0033 16.7 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAM18659.1 - 0.0039 16.5 0.1 4.3 6.6 0.0 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Glycoprot_B_PH1 PF17416.2 GAM18659.1 - 0.061 13.0 1.7 0.12 12.0 0.3 1.9 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B GFO_IDH_MocA PF01408.22 GAM18659.1 - 0.14 13.0 0.1 30 5.5 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold FYVE PF01363.21 GAM18660.1 - 4.5e-19 68.4 2.4 5e-19 68.2 2.4 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 GAM18660.1 - 0.0008 19.6 3.4 0.0011 19.2 3.4 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger DUF4637 PF15470.6 GAM18660.1 - 1.4 8.6 6.0 2.6 7.8 6.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) FNIP PF05725.12 GAM18661.1 - 1.7e-77 255.3 16.4 7.1e-14 51.7 2.0 8.5 7 1 0 8 8 8 7 FNIP Repeat LRR_1 PF00560.33 GAM18661.1 - 0.088 13.4 5.0 99 4.1 0.1 6.0 5 2 0 5 5 5 0 Leucine Rich Repeat TnsE_C PF18623.1 GAM18661.1 - 0.18 11.7 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 TnsE C-terminal domain Prenyltrans PF00432.21 GAM18662.1 - 4e-59 196.0 7.0 3e-13 49.3 0.1 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GAM18662.1 - 9.9e-05 21.6 0.2 0.0014 17.8 0.0 2.5 1 1 2 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAM18662.1 - 0.002 17.3 0.0 4.7 6.2 0.0 3.8 1 1 4 5 5 5 3 Squalene-hopene cyclase N-terminal domain DEAD PF00270.29 GAM18663.1 - 1.3e-32 112.9 0.0 2.4e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM18663.1 - 6.9e-25 87.6 1.1 1.1e-24 86.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAM18663.1 - 0.0055 17.0 0.4 0.064 13.5 0.3 2.9 1 1 1 2 2 2 1 AAA domain CMS1 PF14617.6 GAM18663.1 - 0.05 12.9 0.0 0.05 12.9 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit BUD22 PF09073.10 GAM18663.1 - 0.63 9.3 33.7 1.2 8.4 33.7 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GAM18663.1 - 3 5.9 38.0 5 5.2 38.0 1.2 1 0 0 1 1 1 0 Nop14-like family SSP160 PF06933.11 GAM18663.1 - 4.7 5.3 8.7 6.8 4.7 8.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SDA1 PF05285.12 GAM18663.1 - 4.8 6.5 37.7 9 5.6 37.7 1.4 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 GAM18663.1 - 7.8 5.5 35.3 21 4.1 35.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Formyl_trans_N PF00551.19 GAM18665.1 - 1.6e-23 83.4 0.0 3.2e-23 82.4 0.0 1.4 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 GAM18665.1 - 1.1e-07 32.1 0.0 4.8e-07 29.9 0.0 2.1 2 1 0 2 2 2 1 Formyl transferase, C-terminal domain THF_DHG_CYH_C PF02882.19 GAM18666.1 - 1.6e-55 186.8 0.9 4e-55 185.5 0.3 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 GAM18666.1 - 1.3e-31 109.3 0.5 1.3e-31 109.3 0.5 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 GAM18666.1 - 0.0067 15.7 0.2 0.0067 15.7 0.2 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain CCSAP PF15748.5 GAM18666.1 - 0.035 14.3 20.4 0.05 13.8 20.4 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Shikimate_DH PF01488.20 GAM18666.1 - 0.051 13.6 0.2 0.36 10.9 0.2 2.3 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GREB1 PF15782.5 GAM18666.1 - 1.1 6.2 20.2 1.5 5.9 20.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AdoHcyase_NAD PF00670.21 GAM18666.1 - 2.1 8.4 4.8 0.57 10.2 0.4 2.3 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Hid1 PF12722.7 GAM18666.1 - 2.5 6.1 17.7 3.2 5.8 17.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleo_P87 PF07267.11 GAM18666.1 - 2.9 6.6 18.3 4.3 6.1 18.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SOG2 PF10428.9 GAM18666.1 - 5.5 6.1 27.3 8.6 5.4 27.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein WD40_4 PF16300.5 GAM18667.1 - 3.3e-12 46.1 0.3 5.6e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 GAM18667.1 - 6.9e-11 41.9 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 GAM18667.1 - 7.5e-07 29.8 1.8 0.42 11.6 0.0 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM18667.1 - 4.7e-06 26.8 0.0 0.00041 20.6 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CH PF00307.31 GAM18668.1 - 1.6e-46 157.0 4.7 6.8e-19 68.1 0.0 3.6 3 0 0 3 3 3 3 Calponin homology (CH) domain RhoGEF PF00621.20 GAM18668.1 - 9.3e-43 146.6 2.3 9.3e-43 146.6 2.3 3.2 3 0 0 3 3 3 1 RhoGEF domain CAMSAP_CH PF11971.8 GAM18668.1 - 3.5e-11 42.8 0.7 0.022 14.6 0.0 5.3 4 1 1 5 5 5 3 CAMSAP CH domain PH PF00169.29 GAM18668.1 - 7.3e-08 32.9 0.2 2.3e-07 31.3 0.2 2.0 1 0 0 1 1 1 1 PH domain CDC24 PF06395.11 GAM18668.1 - 3.9e-05 23.8 4.0 0.067 13.5 0.0 3.7 3 0 0 3 3 3 2 CDC24 Calponin PH_13 PF16652.5 GAM18668.1 - 0.012 15.4 2.1 0.11 12.3 2.1 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 GAM18668.1 - 0.022 14.7 0.5 0.3 11.0 0.1 2.7 2 1 0 2 2 2 0 PH domain Herpes_UL14 PF03580.14 GAM18668.1 - 2.4 8.4 10.5 0.31 11.3 0.1 2.5 2 0 0 2 2 2 0 Herpesvirus UL14-like protein FAM75 PF14650.6 GAM18668.1 - 3.2 7.2 21.6 6.7 6.1 21.6 1.5 1 0 0 1 1 1 0 FAM75 family PIG-L PF02585.17 GAM18669.1 - 9.6e-10 39.2 0.0 0.00013 22.6 0.0 2.3 2 0 0 2 2 2 2 GlcNAc-PI de-N-acetylase Ricin_B_lectin PF00652.22 GAM18669.1 - 6.2e-09 36.2 0.4 1.5e-08 34.9 0.4 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain VCBS PF13517.6 GAM18669.1 - 8.6e-05 23.1 16.4 0.35 11.5 0.0 5.6 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CDtoxinA PF03498.14 GAM18669.1 - 0.004 16.8 0.6 1.4 8.5 0.1 2.4 1 1 1 2 2 2 2 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 GAM18669.1 - 0.062 14.0 4.9 0.086 13.6 1.1 3.1 3 1 1 4 4 4 0 Ricin-type beta-trefoil lectin domain-like FG-GAP PF01839.23 GAM18669.1 - 4.5 7.5 9.6 0.49 10.6 0.3 3.2 3 0 0 3 3 3 0 FG-GAP repeat COBRA1 PF06209.13 GAM18670.1 - 6.6e-70 236.3 14.5 6.6e-70 236.3 14.5 1.5 1 1 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) RNase_T PF00929.24 GAM18671.1 - 1.2e-35 123.5 0.3 1.5e-35 123.2 0.3 1.1 1 0 0 1 1 1 1 Exonuclease LCM PF04072.14 GAM18672.1 - 2.3e-36 125.5 0.1 5e-36 124.4 0.1 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Ribosomal_L14e PF01929.17 GAM18673.1 - 2.7e-20 72.7 0.8 2.7e-20 72.7 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 GAM18673.1 - 0.0029 17.5 0.1 0.0065 16.4 0.1 1.6 1 0 0 1 1 1 1 KOW motif V-ATPase_G PF03179.15 GAM18675.1 - 1.7e-27 96.0 10.0 1.9e-27 95.9 10.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit FliD_N PF02465.18 GAM18675.1 - 0.016 15.9 3.5 0.021 15.5 3.5 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus CTP-dep_RFKase PF01982.16 GAM18675.1 - 0.017 15.2 0.2 0.022 14.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF120 ATP-synt_B PF00430.18 GAM18675.1 - 0.043 13.9 10.6 0.03 14.4 9.6 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 GAM18675.1 - 0.13 12.7 7.9 0.18 12.3 7.9 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Mss4 PF04421.13 GAM18676.1 - 2.5e-17 62.8 2.5 3.2e-17 62.4 0.1 2.0 1 1 1 2 2 2 1 Mss4 protein Yippee-Mis18 PF03226.14 GAM18676.1 - 0.11 12.7 3.3 0.56 10.4 3.4 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PET117 PF15786.5 GAM18676.1 - 0.25 11.6 2.2 4.9 7.5 0.0 2.4 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial GDP_Man_Dehyd PF16363.5 GAM18677.1 - 2.3e-57 194.9 0.0 2.7e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAM18677.1 - 2.7e-52 177.6 0.0 3.4e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM18677.1 - 1.1e-15 57.5 0.1 1.2e-14 54.2 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAM18677.1 - 2.6e-15 56.2 0.3 4.4e-15 55.4 0.2 1.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAM18677.1 - 6e-10 38.7 0.0 9.1e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 GAM18677.1 - 3.1e-08 33.7 0.0 5.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 GAM18677.1 - 5.8e-07 29.2 0.2 8.5e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 GAM18677.1 - 1.5e-05 24.3 0.4 0.00031 20.0 0.4 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 GAM18677.1 - 0.00027 20.9 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM18677.1 - 0.018 14.6 0.1 0.081 12.5 0.1 2.0 2 0 0 2 2 2 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 GAM18677.1 - 0.032 14.5 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 GAM18677.1 - 0.12 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3450 PF11932.8 GAM18678.1 - 0.0011 18.3 13.2 0.0011 18.3 13.2 2.9 2 1 0 3 3 3 1 Protein of unknown function (DUF3450) DivIC PF04977.15 GAM18678.1 - 0.0021 17.8 12.4 0.038 13.8 4.1 2.9 2 0 0 2 2 2 2 Septum formation initiator YL1 PF05764.13 GAM18678.1 - 0.0028 17.8 3.4 0.0028 17.8 3.4 2.2 2 0 0 2 2 2 1 YL1 nuclear protein Spt5_N PF11942.8 GAM18678.1 - 0.012 16.6 2.4 0.012 16.6 2.4 3.5 2 1 1 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Csm1_N PF18504.1 GAM18678.1 - 0.012 15.9 1.5 0.012 15.9 1.5 3.3 3 0 0 3 3 3 0 Csm1 N-terminal domain TSC22 PF01166.18 GAM18678.1 - 0.065 13.5 7.8 0.65 10.3 3.6 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 GAM18678.1 - 0.26 11.4 14.2 0.58 10.3 7.7 2.7 2 0 0 2 2 2 0 bZIP transcription factor GIT_CC PF16559.5 GAM18678.1 - 0.67 9.9 13.9 0.23 11.4 3.0 3.4 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor PBP1_TM PF14812.6 GAM18678.1 - 4.1 7.9 15.5 0.36 11.2 10.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 GAM18678.1 - 5.5 6.2 18.6 0.27 10.5 13.0 1.6 2 0 0 2 2 2 0 NOA36 protein RhoGAP PF00620.27 GAM18680.1 - 2.1e-39 134.8 0.6 4.1e-39 133.8 0.1 1.7 2 0 0 2 2 2 1 RhoGAP domain Vps5 PF09325.10 GAM18681.1 - 2.3e-54 184.4 13.4 3.6e-54 183.8 13.4 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 GAM18681.1 - 5.6e-26 90.8 0.1 1.7e-25 89.2 0.1 1.9 1 0 0 1 1 1 1 PX domain OmpH PF03938.14 GAM18681.1 - 0.01 16.1 3.4 0.042 14.2 3.4 2.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2433 PF10360.9 GAM18681.1 - 0.051 13.7 3.5 0.071 13.2 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) DHR10 PF18595.1 GAM18681.1 - 0.11 12.6 10.6 0.073 13.1 5.2 3.0 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain ACCA PF03255.14 GAM18681.1 - 0.19 11.6 2.5 0.56 10.1 2.5 1.8 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GlutR_dimer PF00745.20 GAM18681.1 - 0.63 10.5 4.1 1.7 9.1 0.1 2.8 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF3106 PF11304.8 GAM18681.1 - 0.67 10.5 6.1 0.15 12.5 1.3 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF3106) SET PF00856.28 GAM18681.1 - 0.72 10.2 5.8 0.61 10.5 3.6 1.6 1 1 0 1 1 1 0 SET domain BAR PF03114.18 GAM18681.1 - 0.97 9.0 11.9 3.8 7.1 11.7 1.9 1 1 0 1 1 1 0 BAR domain CREPT PF16566.5 GAM18681.1 - 2.4 8.3 6.4 4 7.6 0.0 2.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Snapin_Pallidin PF14712.6 GAM18681.1 - 6.2 7.3 8.8 6.2 7.3 1.6 3.2 3 1 0 3 3 3 0 Snapin/Pallidin CENP-H PF05837.12 GAM18681.1 - 6.4 7.2 9.4 18 5.8 5.1 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF2524 PF10732.9 GAM18681.1 - 9.1 6.7 8.8 8.7 6.7 4.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) Macoilin PF09726.9 GAM18682.1 - 6.7e-05 21.7 18.1 6.7e-05 21.7 18.1 2.2 2 0 0 2 2 2 1 Macoilin family bZIP_1 PF00170.21 GAM18682.1 - 0.00056 20.0 3.1 0.00056 20.0 3.1 4.1 4 0 0 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 GAM18682.1 - 0.00066 19.7 5.5 0.00066 19.7 5.5 4.3 4 1 1 5 5 5 1 Basic region leucine zipper Peptidase_S64 PF08192.11 GAM18682.1 - 0.031 12.8 41.5 0.0032 16.0 25.4 2.2 2 0 0 2 2 2 0 Peptidase family S64 TFIIA PF03153.13 GAM18682.1 - 0.35 10.8 86.0 2.1 8.2 21.2 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Mem_trans PF03547.18 GAM18682.1 - 2.7 6.3 11.7 0.019 13.4 1.8 1.9 2 0 0 2 2 2 0 Membrane transport protein Glyco_trans_1_2 PF13524.6 GAM18682.1 - 3.6 8.0 8.1 12 6.4 1.9 3.0 3 0 0 3 3 3 0 Glycosyl transferases group 1 bZIP_2 PF07716.15 GAM18683.1 - 7.9e-07 29.1 4.4 7.9e-07 29.1 4.4 4.5 6 0 0 6 6 6 1 Basic region leucine zipper bZIP_1 PF00170.21 GAM18683.1 - 1.5e-05 25.0 3.8 1.5e-05 25.0 3.8 2.7 4 0 0 4 4 4 1 bZIP transcription factor CH PF00307.31 GAM18684.1 - 2e-35 121.2 1.1 3.1e-21 75.6 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain HSCB_C PF07743.13 GAM18684.1 - 0.092 13.2 0.5 0.092 13.2 0.5 3.8 4 2 0 4 4 4 0 HSCB C-terminal oligomerisation domain CorA PF01544.18 GAM18684.1 - 1.7 7.9 5.2 5.6 6.2 5.3 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 GAM18684.1 - 8.5 6.6 8.3 7.7 6.7 5.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Rad60-SLD PF11976.8 GAM18686.1 - 3.8e-08 33.0 0.0 1.4e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAM18686.1 - 4.2e-08 32.8 0.0 4.2e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family TetR_C_29 PF17938.1 GAM18686.1 - 0.012 15.7 0.2 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TFIIA PF03153.13 GAM18686.1 - 0.014 15.4 51.1 0.19 11.7 40.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2052 PF09747.9 GAM18686.1 - 2.7 8.1 16.7 2.6 8.1 9.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 GAM18686.1 - 6.4 6.5 20.4 0.19 11.6 12.0 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Motile_Sperm PF00635.26 GAM18688.1 - 9.8e-20 70.4 1.6 1.2e-19 70.1 0.2 1.9 2 0 0 2 2 2 1 MSP (Major sperm protein) domain TMEM154 PF15102.6 GAM18688.1 - 0.022 14.6 2.5 0.022 14.6 2.5 3.3 3 1 0 3 3 3 0 TMEM154 protein family LAP1C PF05609.12 GAM18688.1 - 0.049 12.7 12.4 0.07 12.2 12.4 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) YL1 PF05764.13 GAM18689.1 - 0.0036 17.5 16.3 0.0036 17.5 16.3 2.2 2 0 0 2 2 2 1 YL1 nuclear protein Transposase_24 PF03004.14 GAM18689.1 - 0.013 15.6 1.7 0.013 15.6 1.7 2.4 2 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) TFIIE-A_C PF11521.8 GAM18689.1 - 0.027 14.8 0.8 0.027 14.8 0.8 2.9 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Pneumo_att_G PF05539.11 GAM18689.1 - 2.6 7.5 18.1 4 6.9 18.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ndc1_Nup PF09531.10 GAM18689.1 - 4.2 6.0 10.0 6.2 5.4 10.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.13 GAM18689.1 - 9 6.1 27.2 0.21 11.5 18.0 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal CEP170_C PF15308.6 GAM18689.1 - 9.4 4.7 28.5 0.012 14.2 17.1 1.8 2 0 0 2 2 2 0 CEP170 C-terminus Voltage_CLC PF00654.20 GAM18690.1 - 1.7e-105 353.2 20.6 1.7e-105 353.2 20.6 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 GAM18690.1 - 5.5e-19 68.4 0.1 1.9e-08 34.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain DUF2207 PF09972.9 GAM18690.1 - 1.2 7.8 9.9 3.1 6.4 0.1 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) FNIP PF05725.12 GAM18692.1 - 8e-40 134.8 24.8 9.6e-12 44.9 0.2 6.4 3 1 4 7 7 7 7 FNIP Repeat ABC_tran PF00005.27 GAM18693.1 - 2.2e-35 122.2 0.0 3.8e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAM18693.1 - 4.2e-34 118.5 15.5 5.7e-34 118.0 15.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GAM18693.1 - 5e-07 29.4 0.2 2.5e-05 23.8 0.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAM18693.1 - 0.00056 19.7 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 GAM18693.1 - 0.001 18.8 0.2 0.0049 16.6 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM18693.1 - 0.0025 18.2 0.0 0.0049 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAM18693.1 - 0.0035 17.4 0.0 0.0083 16.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAM18693.1 - 0.0046 16.2 0.1 0.02 14.1 0.0 2.0 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.12 GAM18693.1 - 0.0051 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 GAM18693.1 - 0.0055 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAM18693.1 - 0.0061 16.8 1.8 0.53 10.5 0.4 3.0 2 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 GAM18693.1 - 0.007 15.6 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 GAM18693.1 - 0.0077 16.2 0.0 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 GAM18693.1 - 0.013 15.6 0.1 0.034 14.2 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 GAM18693.1 - 0.024 15.2 0.0 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAM18693.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1673 PF07895.11 GAM18693.1 - 0.043 13.5 3.3 2.3 7.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) FtsK_SpoIIIE PF01580.18 GAM18693.1 - 0.046 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_21 PF13304.6 GAM18693.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAM18693.1 - 0.079 13.5 0.6 0.12 12.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 GAM18693.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gpi16 PF04113.14 GAM18694.1 - 0.066 11.7 0.0 0.069 11.6 0.0 1.0 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component L51_S25_CI-B8 PF05047.16 GAM18695.1 - 0.038 13.9 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TPR_14 PF13428.6 GAM18696.1 - 1.5e-13 50.3 15.5 0.06 14.2 0.0 9.9 8 2 2 10 10 8 3 Tetratricopeptide repeat TPR_15 PF13429.6 GAM18696.1 - 7.8e-10 38.4 17.3 0.0002 20.7 0.1 5.7 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAM18696.1 - 2.6e-09 37.5 1.6 5.5 7.6 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAM18696.1 - 3.6e-09 36.7 27.6 0.024 14.6 0.1 8.4 6 3 1 7 7 7 4 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 GAM18696.1 - 9.2e-08 32.3 12.3 0.044 14.1 0.1 6.6 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM18696.1 - 5.9e-07 29.2 3.2 0.12 12.6 0.2 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Suf PF05843.14 GAM18696.1 - 1.2e-06 28.7 44.3 0.013 15.5 0.0 6.2 4 3 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_2 PF07719.17 GAM18696.1 - 6.4e-06 25.9 20.2 0.053 13.6 0.2 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM18696.1 - 0.079 13.0 0.1 0.079 13.0 0.1 4.7 8 0 0 8 8 4 0 Tetratricopeptide repeat HAT PF02184.16 GAM18696.1 - 0.19 11.7 8.7 1.2 9.2 0.1 6.0 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat TPR_6 PF13174.6 GAM18696.1 - 0.22 12.2 16.5 47 4.9 0.1 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM18696.1 - 0.23 11.4 0.1 0.23 11.4 0.1 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat SF3A3 PF16837.5 GAM18696.1 - 0.25 11.9 15.8 0.31 11.6 0.3 5.5 7 0 0 7 7 6 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 PBP1_TM PF14812.6 GAM18696.1 - 0.68 10.3 8.5 2.6 8.5 8.5 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_16 PF13432.6 GAM18696.1 - 5.9 7.6 16.2 44 4.9 0.0 6.4 8 1 0 8 8 6 0 Tetratricopeptide repeat NOA36 PF06524.12 GAM18696.1 - 7.8 5.7 12.6 13 5.0 12.6 1.3 1 0 0 1 1 1 0 NOA36 protein AMP-binding PF00501.28 GAM18697.1 - 3e-60 204.0 0.0 4.5e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAM18697.1 - 2.7e-53 180.8 0.0 4.4e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 GAM18697.1 - 6.8e-07 29.0 0.1 2.5e-06 27.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM18697.1 - 9.3e-06 24.8 0.1 3.6e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 GAM18697.1 - 0.002 18.4 0.1 0.0043 17.4 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 GAM18697.1 - 0.039 13.4 0.1 0.13 11.6 0.1 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase ZZ PF00569.17 GAM18697.1 - 0.052 13.4 3.2 0.1 12.4 3.2 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Trigger_N PF05697.13 GAM18697.1 - 0.076 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) Hormone_4 PF00220.17 GAM18697.1 - 0.36 10.9 3.0 1.3 9.2 3.0 2.1 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain TPR_2 PF07719.17 GAM18698.1 - 6.5e-11 41.5 9.4 2.1e-05 24.3 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM18698.1 - 7.9e-07 28.7 2.7 0.0016 18.1 0.1 3.2 2 1 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 GAM18698.1 - 1.3e-06 28.8 3.2 0.013 16.0 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat SET PF00856.28 GAM18698.1 - 1.5e-06 28.7 0.0 1.2e-05 25.8 0.0 2.5 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 GAM18698.1 - 2.3e-06 27.2 10.6 2.7e-05 23.8 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM18698.1 - 3.8e-05 23.5 5.2 0.7 10.3 0.3 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM18698.1 - 0.00013 22.6 2.3 0.03 15.0 0.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM18698.1 - 0.00014 22.4 1.5 0.04 14.7 0.1 3.4 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM18698.1 - 0.00022 21.6 2.0 0.0078 16.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM18698.1 - 0.0032 17.7 3.3 0.82 10.0 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 GAM18698.1 - 0.052 14.0 0.7 0.74 10.2 0.3 2.8 2 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 GAM18698.1 - 0.093 12.9 0.1 0.61 10.3 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM18698.1 - 0.22 11.6 1.2 18 5.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAM18698.1 - 0.57 10.7 5.8 5.8 7.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM18698.1 - 0.89 9.8 7.8 6.1 7.1 1.9 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Beta_helix PF13229.6 GAM18699.1 - 2.6e-15 56.6 38.7 4.1e-08 33.2 12.1 3.6 1 1 2 3 3 3 3 Right handed beta helix region NosD PF05048.13 GAM18699.1 - 1.3e-07 31.2 22.5 0.0007 18.9 13.7 3.5 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Cornifin PF02389.15 GAM18699.1 - 1.4e-05 25.3 6.2 2.3e-05 24.6 6.2 1.2 1 0 0 1 1 1 1 Cornifin (SPRR) family CBM_4_9 PF02018.17 GAM18699.1 - 0.0016 18.7 2.0 0.0016 18.7 2.0 2.2 2 0 0 2 2 2 1 Carbohydrate binding domain SOG2 PF10428.9 GAM18699.1 - 7.8 5.6 12.3 11 5.1 12.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MCD PF05292.11 GAM18701.1 - 2.7e-53 181.2 0.2 1.9e-30 106.3 0.0 2.1 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase C-terminal domain PRK PF00485.18 GAM18702.1 - 5.7e-50 169.8 0.1 6.9e-50 169.5 0.1 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAM18702.1 - 3e-08 34.3 0.0 5.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAM18702.1 - 0.00014 22.3 0.8 0.0014 19.0 0.8 2.3 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 GAM18702.1 - 0.00023 21.4 0.1 0.00038 20.6 0.1 1.5 1 1 0 1 1 1 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 GAM18702.1 - 0.0013 18.5 0.1 0.63 9.7 0.0 2.4 3 0 0 3 3 3 2 Cytidylate kinase MobB PF03205.14 GAM18702.1 - 0.0016 18.4 0.0 0.037 13.9 0.0 2.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 GAM18702.1 - 0.0017 17.4 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein CoaE PF01121.20 GAM18702.1 - 0.0021 17.8 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 1 Dephospho-CoA kinase Zeta_toxin PF06414.12 GAM18702.1 - 0.0031 16.8 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin ATPase_2 PF01637.18 GAM18702.1 - 0.0094 15.9 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 GAM18702.1 - 0.019 15.1 0.0 0.03 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 GAM18702.1 - 0.019 14.8 0.0 0.049 13.5 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 GAM18702.1 - 0.024 14.4 0.0 0.06 13.1 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 GAM18702.1 - 0.025 14.9 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 GAM18702.1 - 0.026 14.2 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.15 GAM18702.1 - 0.035 14.0 0.2 0.12 12.3 0.0 1.9 2 1 0 2 2 2 0 NTPase Spore_II_R PF09551.10 GAM18702.1 - 0.048 14.1 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) AAA_14 PF13173.6 GAM18702.1 - 0.052 13.6 0.1 0.16 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 GAM18702.1 - 0.052 13.2 0.1 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_24 PF13479.6 GAM18702.1 - 0.057 13.1 0.2 0.16 11.7 0.1 1.7 1 1 1 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 GAM18702.1 - 0.071 12.0 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain dNK PF01712.19 GAM18702.1 - 0.071 12.9 0.7 0.38 10.6 0.7 2.0 1 1 0 1 1 1 0 Deoxynucleoside kinase KTI12 PF08433.10 GAM18702.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.18 GAM18702.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.6 GAM18702.1 - 0.15 12.4 0.1 0.24 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain ADK PF00406.22 GAM18702.1 - 0.33 11.0 1.2 5.1 7.2 0.0 2.6 3 0 0 3 3 3 0 Adenylate kinase TPT PF03151.16 GAM18704.1 - 4.8e-25 88.5 30.5 8.1e-25 87.8 30.5 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAM18704.1 - 4e-08 33.5 45.1 0.00042 20.5 15.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 GAM18704.1 - 0.0037 16.3 10.7 0.0037 16.3 10.7 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like CytochromB561_N PF09786.9 GAM18704.1 - 1.1 8.2 12.0 0.24 10.3 0.5 2.4 2 0 0 2 2 2 0 Cytochrome B561, N terminal 7TMR-DISM_7TM PF07695.11 GAM18704.1 - 4.4 7.1 43.7 0.41 10.5 8.7 2.5 2 0 0 2 2 2 0 7TM diverse intracellular signalling SR-25 PF10500.9 GAM18704.1 - 5.5 6.5 20.6 2.1 7.9 5.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PRA1 PF03208.19 GAM18705.1 - 4.5e-27 94.4 2.6 5.6e-27 94.1 2.6 1.0 1 0 0 1 1 1 1 PRA1 family protein TMEMspv1-c74-12 PF11044.8 GAM18705.1 - 0.15 12.1 3.7 1.2 9.1 0.0 2.7 2 1 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein YjcZ_2 PF09680.10 GAM18705.1 - 1.9 8.2 9.2 5.6 6.7 0.9 3.4 3 0 0 3 3 3 0 Family of unknown function DHHC PF01529.20 GAM18705.1 - 2.4 8.3 4.3 3.1 7.9 4.3 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase SdpI PF13630.6 GAM18705.1 - 8.3 6.6 7.6 1.6 9.0 1.8 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family FERM_N PF09379.10 GAM18707.1 - 2.2e-05 24.3 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 FERM N-terminal domain RA PF00788.23 GAM18707.1 - 0.00018 22.1 0.5 1 10.0 0.0 3.3 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain TUG-UBL1 PF11470.8 GAM18707.1 - 0.024 14.9 0.0 4.8 7.5 0.0 3.1 2 0 0 2 2 2 0 TUG ubiquitin-like domain DUF3584 PF12128.8 GAM18707.1 - 0.57 7.6 69.7 0.35 8.3 35.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 GAM18707.1 - 1.1 9.7 74.1 0.26 11.7 26.1 3.2 2 1 1 3 3 3 0 Fez1 TIG PF01833.24 GAM18708.1 - 1.8e-25 88.8 59.8 1.7e-07 31.2 5.7 6.9 6 1 1 7 7 7 6 IPT/TIG domain DUF5008 PF16400.5 GAM18708.1 - 0.1 12.7 0.0 0.77 9.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5008) zf-B_box PF00643.24 GAM18709.1 - 4.9e-07 29.8 6.2 9.4e-07 28.9 6.2 1.4 1 0 0 1 1 1 1 B-box zinc finger Kelch_6 PF13964.6 GAM18709.1 - 4e-05 23.7 6.8 4.1 7.8 0.1 6.3 6 0 0 6 6 6 1 Kelch motif Kelch_1 PF01344.25 GAM18709.1 - 0.0035 16.9 7.9 1.2 8.8 0.1 4.6 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 GAM18709.1 - 0.012 15.6 0.4 12 6.0 0.0 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain LRR_adjacent PF08191.11 GAM18709.1 - 0.081 13.1 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 0 LRR adjacent zf-UBR PF02207.20 GAM18709.1 - 0.085 13.0 3.9 0.22 11.7 3.9 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Kelch_2 PF07646.15 GAM18709.1 - 0.36 10.9 3.3 20 5.4 0.0 4.3 3 1 1 4 4 4 0 Kelch motif RabGAP-TBC PF00566.18 GAM18710.1 - 7.9e-45 153.1 9.1 7.9e-45 153.1 9.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_1 PF00036.32 GAM18710.1 - 0.0012 18.2 1.3 0.004 16.6 0.5 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GAM18710.1 - 0.0036 17.1 2.4 0.083 12.9 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 GAM18710.1 - 0.04 14.4 3.6 0.25 11.8 0.4 2.9 1 1 1 2 2 2 0 EF-hand domain pair DUF3915 PF13054.6 GAM18710.1 - 5.6 7.0 7.5 15 5.6 7.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) SUIM_assoc PF16619.5 GAM18711.1 - 0.15 12.1 0.0 0.15 12.1 0.0 9.2 5 1 2 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 RhoGEF PF00621.20 GAM18712.1 - 6.2e-37 127.6 6.5 1.1e-36 126.8 6.5 1.4 1 0 0 1 1 1 1 RhoGEF domain pXO2-72 PF17443.2 GAM18712.1 - 0.027 14.7 0.1 0.061 13.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein pXO2-72 PH_5 PF15405.6 GAM18712.1 - 0.062 13.4 0.2 0.062 13.4 0.2 3.3 2 1 2 4 4 4 0 Pleckstrin homology domain PH PF00169.29 GAM18712.1 - 0.2 12.2 1.8 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 PH domain ATG16 PF08614.11 GAM18713.1 - 0.00018 21.8 1.9 0.00018 21.8 1.9 2.8 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 GAM18713.1 - 0.0013 19.0 4.4 0.0013 19.0 4.4 2.0 2 0 0 2 2 2 1 Csm1 N-terminal domain UPF0242 PF06785.11 GAM18713.1 - 0.0059 16.7 1.9 0.0059 16.7 1.9 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Pox_A_type_inc PF04508.12 GAM18713.1 - 0.023 14.5 0.8 0.023 14.5 0.8 1.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat XhlA PF10779.9 GAM18713.1 - 0.027 14.7 3.4 0.054 13.7 3.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA TSC22 PF01166.18 GAM18713.1 - 0.039 14.3 6.1 0.66 10.3 0.9 2.9 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 GAM18713.1 - 0.62 10.2 6.0 4.8 7.4 4.6 2.3 1 1 1 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.11 GAM18713.1 - 0.68 10.4 5.5 2.5 8.6 5.5 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 GAM18713.1 - 1.5 9.1 12.6 0.18 12.1 6.9 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain bZIP_2 PF07716.15 GAM18713.1 - 3.9 7.6 9.8 2.7 8.1 3.7 2.6 1 1 1 2 2 2 0 Basic region leucine zipper Big_2 PF02368.18 GAM18714.1 - 1.8e-16 59.7 13.1 0.00011 22.0 0.1 8.8 9 0 0 9 9 9 4 Bacterial Ig-like domain (group 2) BiPBP_C PF06832.12 GAM18714.1 - 1.5e-06 28.1 0.0 0.008 16.2 0.0 3.6 2 1 1 3 3 3 2 Penicillin-Binding Protein C-terminus Family T2SS-T3SS_pil_N PF13629.6 GAM18714.1 - 1.7e-05 24.5 6.5 0.66 9.8 0.0 6.3 6 0 0 6 6 6 2 Pilus formation protein N terminal region Glyco_transf_24 PF18404.1 GAM18715.1 - 2e-146 486.5 4.5 4.5e-146 485.3 4.5 1.6 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 GAM18715.1 - 2.6e-34 119.3 0.3 2.6e-34 119.3 0.3 3.9 4 0 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 GAM18715.1 - 1.6e-24 86.4 4.7 6.1e-24 84.5 1.5 3.4 4 0 0 4 4 4 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 GAM18715.1 - 5.3e-20 71.6 0.0 1.3e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 GAM18715.1 - 1.2e-19 70.9 0.5 4.3e-19 69.1 0.5 2.0 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 GAM18715.1 - 2.7e-11 43.8 1.7 2.1e-09 37.7 1.5 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 GAM18715.1 - 1.8e-06 27.7 0.4 1.8e-06 27.7 0.4 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 8 DUF2076 PF09849.9 GAM18715.1 - 0.021 14.9 0.1 0.021 14.9 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) PTR2 PF00854.21 GAM18716.1 - 1.8e-65 221.4 0.2 2.6e-65 220.8 0.2 1.2 1 0 0 1 1 1 1 POT family TPR_1 PF00515.28 GAM18717.1 - 2e-10 40.0 7.3 3.9e-07 29.6 0.3 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM18717.1 - 5e-09 35.6 6.3 6.1e-05 22.8 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM18717.1 - 3.6e-06 26.5 5.5 8e-06 25.4 0.6 3.1 3 0 0 3 3 3 1 TPR repeat RPAP3_C PF13877.6 GAM18717.1 - 4.7e-05 23.9 4.0 0.051 14.1 0.2 3.2 2 1 1 3 3 3 2 Potential Monad-binding region of RPAP3 TPR_8 PF13181.6 GAM18717.1 - 0.0013 18.7 6.4 0.0042 17.2 0.4 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM18717.1 - 0.003 17.6 2.5 0.51 10.5 0.4 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 GAM18717.1 - 0.028 14.8 3.8 0.045 14.1 0.4 3.2 4 0 0 4 4 2 0 Tetratricopeptide repeat Strep_SA_rep PF06696.11 GAM18717.1 - 0.029 14.4 0.1 0.091 12.8 0.1 1.8 1 0 0 1 1 1 0 Streptococcal surface antigen repeat TPR_12 PF13424.6 GAM18717.1 - 0.04 14.2 1.5 1.2 9.5 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM18717.1 - 0.052 13.6 1.0 0.44 10.7 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM18717.1 - 0.074 13.6 3.8 0.26 11.8 1.1 2.8 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAM18717.1 - 0.11 12.6 3.8 0.5 10.4 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM18717.1 - 0.34 10.8 2.2 13 5.9 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat GARS_A PF01071.19 GAM18718.1 - 6.8e-74 247.9 0.1 1.1e-73 247.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ribosomal_L7Ae PF01248.26 GAM18718.1 - 8.5e-26 89.5 0.1 2.1e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AIRS_C PF02769.22 GAM18718.1 - 1.4e-24 87.0 0.0 5.2e-24 85.2 0.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 GAM18718.1 - 2.8e-24 85.2 1.4 1.5e-23 82.8 0.1 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 GAM18718.1 - 3.1e-14 53.4 1.1 1.1e-13 51.7 1.1 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain GARS_N PF02844.15 GAM18718.1 - 6e-14 52.6 0.4 2.3e-13 50.7 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain ATP-grasp PF02222.22 GAM18718.1 - 2.5e-06 27.2 0.0 4.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 GAM18718.1 - 5.4e-06 26.1 0.1 1.2e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 GAM18718.1 - 9.7e-05 22.0 0.0 0.00025 20.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 GAM18718.1 - 0.00023 20.8 0.0 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 GAM18718.1 - 0.00031 20.8 0.0 0.00074 19.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain PELOTA_1 PF15608.6 GAM18718.1 - 0.037 13.9 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 PELOTA RNA binding domain LRR_9 PF14580.6 GAM18719.1 - 9.5e-13 48.0 1.0 9.5e-13 48.0 1.0 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 GAM18719.1 - 3.2e-10 40.1 5.3 0.00018 21.8 0.5 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM18719.1 - 0.00023 20.8 7.6 0.00041 20.0 0.4 2.8 1 1 2 3 3 3 2 Leucine rich repeat DUF4407 PF14362.6 GAM18719.1 - 5 6.4 7.4 7.9 5.7 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NARP1 PF12569.8 GAM18719.1 - 6.3 5.6 15.1 11 4.8 15.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SdrD_B PF17210.3 GAM18720.1 - 0.0069 16.6 0.2 0.0069 16.6 0.2 2.3 1 1 1 2 2 2 1 SdrD B-like domain Mucin PF01456.17 GAM18720.1 - 0.25 11.3 11.2 0.32 11.0 11.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein RRM_1 PF00076.22 GAM18721.1 - 1.3e-60 201.2 0.0 2.9e-21 75.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM18721.1 - 5e-13 48.7 0.0 0.0029 17.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAM18721.1 - 8.1e-06 25.8 0.0 0.033 14.2 0.0 2.8 3 0 0 3 3 3 2 RNA binding motif RRM_occluded PF16842.5 GAM18721.1 - 2.3e-05 24.2 0.0 0.0015 18.4 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 GAM18721.1 - 9.3e-05 22.5 0.0 0.15 12.2 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 GAM18721.1 - 0.00072 19.6 0.8 0.66 10.1 0.0 3.5 3 0 0 3 3 3 1 Limkain b1 Nop14 PF04147.12 GAM18721.1 - 1.7 6.8 21.7 0.75 7.9 17.3 1.9 2 0 0 2 2 2 0 Nop14-like family Presenilin PF01080.17 GAM18721.1 - 7.3 5.2 23.0 2.3 6.9 1.6 2.2 2 0 0 2 2 2 0 Presenilin CBM49 PF09478.10 GAM18722.1 - 3.3e-06 27.3 0.0 5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Toxin_10 PF05431.11 GAM18722.1 - 0.013 14.9 0.7 0.018 14.5 0.7 1.1 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 UQ_con PF00179.26 GAM18723.1 - 5.2e-38 129.9 0.1 1.1e-37 128.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 GAM18723.1 - 0.0093 15.8 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 GAM18723.1 - 0.013 15.8 0.3 0.028 14.7 0.3 1.5 1 1 0 1 1 1 0 RWD domain SUIM_assoc PF16619.5 GAM18723.1 - 0.51 10.4 6.8 0.35 11.0 2.7 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Not3 PF04065.15 GAM18726.1 - 0.00019 21.0 6.7 0.00023 20.7 6.7 1.0 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component ABC_tran_CTD PF16326.5 GAM18726.1 - 0.00039 20.6 9.8 0.0068 16.6 0.9 2.8 1 1 2 3 3 3 2 ABC transporter C-terminal domain DUF3584 PF12128.8 GAM18726.1 - 0.042 11.4 18.4 0.051 11.1 18.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 GAM18726.1 - 0.08 13.3 2.1 11 6.5 0.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GPS2_interact PF15784.5 GAM18726.1 - 0.12 12.9 0.9 0.12 12.9 0.9 2.4 1 1 2 3 3 3 0 G-protein pathway suppressor 2-interacting domain AbiTii PF18864.1 GAM18726.1 - 0.14 12.3 5.0 0.16 12.1 5.0 1.2 1 0 0 1 1 1 0 AbiTii V_ATPase_I PF01496.19 GAM18726.1 - 0.22 9.4 8.9 0.26 9.2 8.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 GAM18726.1 - 0.26 10.6 15.8 0.34 10.2 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Enkurin PF13864.6 GAM18726.1 - 0.32 11.5 5.8 0.34 11.4 0.7 2.3 1 1 1 2 2 2 0 Calmodulin-binding DUF2400 PF09674.10 GAM18726.1 - 0.46 10.4 5.5 0.59 10.1 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) YabA PF06156.13 GAM18726.1 - 0.55 10.9 10.6 0.14 12.8 6.5 2.0 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 GAM18726.1 - 0.78 8.3 8.2 1.1 7.8 8.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Syntaxin-6_N PF09177.11 GAM18726.1 - 0.91 10.1 6.8 0.78 10.3 4.0 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Exonuc_VII_L PF02601.15 GAM18726.1 - 0.91 9.0 12.3 1.1 8.7 12.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S46 PF10459.9 GAM18726.1 - 1.3 7.6 10.0 1.5 7.4 10.0 1.0 1 0 0 1 1 1 0 Peptidase S46 FliJ PF02050.16 GAM18726.1 - 1.3 9.3 30.4 0.026 14.7 19.0 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Spc24 PF08286.11 GAM18726.1 - 2 8.7 12.4 4 7.7 1.9 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 MerR-DNA-bind PF09278.11 GAM18726.1 - 2.4 8.7 13.0 5.1 7.7 2.6 2.4 1 1 1 2 2 2 0 MerR, DNA binding Uds1 PF15456.6 GAM18726.1 - 3 8.0 10.5 19 5.4 10.6 1.8 1 1 1 2 2 2 0 Up-regulated During Septation AAA_lid_9 PF17871.1 GAM18726.1 - 3.7 7.5 10.0 1.3 8.9 0.9 2.2 1 1 1 2 2 2 0 AAA lid domain THOC7 PF05615.13 GAM18726.1 - 4.1 7.7 17.3 2.1e+03 -1.1 17.3 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 DUF1664 PF07889.12 GAM18726.1 - 4.8 7.2 7.4 6.2 6.9 5.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HemX PF04375.14 GAM18726.1 - 4.9 6.4 25.2 6.8 5.9 25.2 1.3 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Muted PF14942.6 GAM18726.1 - 9 6.6 15.3 30 4.9 15.2 1.7 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Ricin_B_lectin PF00652.22 GAM18728.1 - 2.2e-08 34.4 0.6 3e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 GAM18728.1 - 1.8e-05 24.4 0.4 0.0055 16.3 0.1 2.9 1 1 2 3 3 3 2 Cytolethal distending toxin A/C domain Endotoxin_N PF03945.14 GAM18729.1 - 1.1e-07 31.8 5.2 2.8e-07 30.5 5.2 1.5 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain Ricin_B_lectin PF00652.22 GAM18729.1 - 2.1e-06 28.0 0.3 8.5e-06 26.0 0.2 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain FAS_I_H PF18314.1 GAM18729.1 - 0.028 14.0 0.3 0.043 13.4 0.3 1.2 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain DUF5532 PF17673.1 GAM18729.1 - 0.15 12.1 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5532) SNF2_N PF00176.23 GAM18730.1 - 1.3e-61 208.3 0.9 2.3e-61 207.5 0.9 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 GAM18730.1 - 1.7e-20 72.7 9.6 3.5e-12 46.0 0.4 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 GAM18730.1 - 9.4e-18 64.6 0.3 4.9e-17 62.3 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM18730.1 - 1.3e-10 41.6 1.1 6.9e-10 39.2 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1086 PF06461.11 GAM18730.1 - 0.0016 18.3 1.0 0.41 10.5 0.0 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) DEAD PF00270.29 GAM18730.1 - 0.0072 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3385 PF11865.8 GAM18730.1 - 0.06 13.2 0.1 0.33 10.8 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) SDA1 PF05285.12 GAM18730.1 - 0.1 12.0 90.1 0.06 12.8 35.4 4.7 4 0 0 4 4 4 0 SDA1 AT_hook PF02178.19 GAM18730.1 - 0.85 9.7 9.4 1.7 8.7 1.2 3.1 2 0 0 2 2 2 0 AT hook motif CHDCT2 PF08074.11 GAM18730.1 - 3.7 7.7 12.9 0.55 10.4 0.1 4.5 4 1 0 4 4 4 0 CHDCT2 (NUC038) domain RhoGAP PF00620.27 GAM18731.1 - 0.00035 20.4 4.5 0.0024 17.7 0.4 2.8 3 0 0 3 3 3 2 RhoGAP domain RasGEF_N_2 PF14663.6 GAM18731.1 - 0.56 10.6 4.3 5.3 7.5 0.2 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain PBP1_TM PF14812.6 GAM18732.1 - 0.095 13.1 2.2 0.33 11.4 0.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mucin PF01456.17 GAM18732.1 - 0.69 9.9 14.2 0.16 11.9 4.4 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein CBM49 PF09478.10 GAM18733.1 - 1.8e-14 53.8 0.2 4.4e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF1748 PF08520.10 GAM18734.1 - 1.1e-11 44.4 0.1 1.5e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MMR_HSR1 PF01926.23 GAM18735.1 - 5.7e-15 55.4 0.0 1.2e-12 47.9 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM18735.1 - 2.9e-05 24.0 2.6 0.0021 18.0 0.2 3.0 3 1 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 GAM18735.1 - 3.1e-05 23.6 0.0 0.00058 19.4 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAM18735.1 - 0.022 14.3 3.0 2.3 7.7 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Roc PF08477.13 GAM18735.1 - 0.053 13.7 0.0 0.64 10.3 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GAM18735.1 - 1.7 8.7 13.6 1.2 9.1 7.9 3.6 2 1 0 2 2 2 0 Dynamin family Caldesmon PF02029.15 GAM18736.1 - 0.36 9.6 32.6 0.63 8.7 32.6 1.4 1 1 0 1 1 1 0 Caldesmon EF-hand_1 PF00036.32 GAM18738.1 - 1.8e-19 67.7 1.6 4.6e-05 22.7 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 GAM18738.1 - 2.2e-18 66.4 1.0 2.2e-11 44.0 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM18738.1 - 1.5e-16 58.8 1.7 1.3e-06 27.8 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 GAM18738.1 - 9.6e-11 40.7 1.9 0.0025 17.3 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 GAM18738.1 - 2e-10 40.4 2.9 6.6e-07 29.1 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 GAM18738.1 - 4.4e-06 26.9 0.2 0.007 16.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 GAM18738.1 - 0.0014 19.5 0.0 0.0018 19.1 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain DUF5580 PF17743.1 GAM18738.1 - 0.0015 17.2 0.0 0.0017 17.0 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SPARC_Ca_bdg PF10591.9 GAM18738.1 - 0.0026 18.1 0.1 0.022 15.1 0.0 2.0 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 GAM18738.1 - 0.0069 16.5 0.1 0.061 13.4 0.1 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Citrate_synt PF00285.21 GAM18738.1 - 0.2 10.7 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain Dockerin_1 PF00404.18 GAM18738.1 - 0.89 9.8 3.9 5.1 7.4 0.6 3.0 2 1 0 2 2 2 0 Dockerin type I domain RRM_1 PF00076.22 GAM18739.1 - 0.013 15.3 0.1 0.028 14.2 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_6 PF13516.6 GAM18740.1 - 3.1e-21 73.6 24.9 0.00019 21.2 0.1 7.4 7 0 0 7 7 7 6 Leucine Rich repeat LRR_1 PF00560.33 GAM18740.1 - 6.3e-13 47.3 5.6 0.032 14.8 0.2 7.1 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_4 PF12799.7 GAM18740.1 - 5.9e-11 42.4 11.9 0.018 15.5 0.3 6.1 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM18740.1 - 9e-08 31.8 11.2 0.079 12.7 1.1 5.3 4 1 1 5 5 5 3 Leucine rich repeat Carm_PH PF17888.1 GAM18740.1 - 0.0014 19.0 0.0 0.0038 17.6 0.0 1.8 1 0 0 1 1 1 1 Carmil pleckstrin homology domain bPH_3 PF14470.6 GAM18740.1 - 0.044 14.1 0.1 1.7 9.1 0.0 2.8 2 1 0 2 2 2 0 Bacterial PH domain C1q PF00386.21 GAM18741.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 C1q domain zf-4CXXC_R1 PF10497.9 GAM18742.1 - 0.98 9.7 9.6 0.26 11.5 5.5 2.1 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 MRPL52 PF18699.1 GAM18743.1 - 5.7e-26 90.5 2.9 8.6e-26 90.0 2.9 1.3 1 0 0 1 1 1 1 Mitoribosomal protein mL52 YtxH PF12732.7 GAM18743.1 - 0.45 11.1 2.4 0.61 10.7 2.0 1.4 1 1 0 1 1 1 0 YtxH-like protein CDC37_N PF03234.14 GAM18743.1 - 0.57 11.1 9.5 0.74 10.7 9.5 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding LRR_6 PF13516.6 GAM18745.1 - 1.7e-09 37.0 18.2 0.24 11.6 0.0 11.1 12 0 0 12 12 12 3 Leucine Rich repeat LRR_4 PF12799.7 GAM18745.1 - 4.3e-09 36.5 18.2 0.21 12.1 0.0 9.0 5 3 5 10 10 10 3 Leucine Rich repeats (2 copies) Spt20 PF12090.8 GAM18745.1 - 0.013 15.1 7.1 0.032 13.8 7.1 1.6 1 0 0 1 1 1 0 Spt20 family Peptidase_C36 PF05415.11 GAM18745.1 - 0.031 14.5 0.1 0.085 13.1 0.1 1.8 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase TFIIA PF03153.13 GAM18745.1 - 0.11 12.5 6.0 0.052 13.5 0.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HSP20 PF00011.21 GAM18746.1 - 3.3e-12 46.4 0.0 1.2e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM18746.1 - 3.7e-07 29.6 0.2 5.6e-06 25.8 0.2 2.3 1 1 0 1 1 1 1 HSP20-like domain found in ArsA KRTAP PF11759.8 GAM18746.1 - 0.033 14.7 6.3 0.033 14.7 6.3 1.5 2 0 0 2 2 2 0 Keratin-associated matrix G-alpha PF00503.20 GAM18747.1 - 3e-90 302.9 0.1 3.9e-90 302.6 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM18747.1 - 1.4e-13 50.7 0.0 2.9e-09 36.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAM18747.1 - 0.00071 19.8 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAM18747.1 - 0.0014 18.0 0.0 0.69 9.2 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM18747.1 - 0.028 14.5 0.0 6.2 6.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM18747.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Phosphorylase PF00343.20 GAM18748.1 - 0 1045.2 0.8 0 1044.9 0.8 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.25 GAM18749.1 - 7.2e-73 245.2 0.0 8.8e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18749.1 - 2.4e-37 128.7 0.0 3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 GAM18749.1 - 1.1e-20 74.1 0.1 2.2e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM18749.1 - 1.8e-07 31.5 0.3 3.9e-06 27.2 0.3 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_C PF00433.24 GAM18749.1 - 2.1e-07 31.5 0.2 4.6e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_3 PF14593.6 GAM18749.1 - 1.3e-06 28.4 0.0 3.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM18749.1 - 0.00012 22.3 0.8 0.00066 19.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.6 GAM18749.1 - 0.00076 18.9 0.0 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PH_6 PF15406.6 GAM18749.1 - 0.0075 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 GAM18749.1 - 0.013 15.9 0.4 0.061 13.7 0.0 2.3 2 2 0 2 2 2 0 Pleckstrin homology domain FTA2 PF13095.6 GAM18749.1 - 0.063 12.9 0.1 2.3 7.8 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAM18749.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAM18749.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NST1 PF13945.6 GAM18750.1 - 1.3e-49 168.9 31.6 1.3e-49 168.9 31.6 7.0 3 2 4 7 7 7 1 Salt tolerance down-regulator DUF3439 PF11921.8 GAM18750.1 - 5.2 7.1 7.4 0.63 10.0 2.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) UDPGP PF01704.18 GAM18751.1 - 3.5e-186 618.8 1.0 4.3e-186 618.5 1.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase FNIP PF05725.12 GAM18752.1 - 8.1e-72 237.2 34.9 3.5e-13 49.5 0.4 8.5 6 1 2 9 9 9 8 FNIP Repeat PseudoU_synth_2 PF00849.22 GAM18753.1 - 5.3e-31 107.9 2.1 1.6e-30 106.3 0.0 2.5 2 0 0 2 2 2 1 RNA pseudouridylate synthase Ndc1_Nup PF09531.10 GAM18753.1 - 0.001 17.9 7.3 0.0015 17.4 7.3 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TGS PF02824.21 GAM18753.1 - 0.028 14.5 0.3 1 9.5 0.1 2.9 3 0 0 3 3 3 0 TGS domain Apt1 PF10351.9 GAM18753.1 - 0.25 10.1 13.9 0.043 12.7 7.5 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain HS1_rep PF02218.15 GAM18753.1 - 0.78 10.1 3.7 8.1 6.9 0.5 2.6 2 0 0 2 2 2 0 Repeat in HS1/Cortactin Hid1 PF12722.7 GAM18753.1 - 1.5 6.9 12.0 2.5 6.1 12.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 GAM18753.1 - 7 5.1 17.0 0.054 12.0 8.5 1.7 2 0 0 2 2 2 0 Macoilin family SR-25 PF10500.9 GAM18753.1 - 7.5 6.1 29.2 0.19 11.3 17.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_L29e PF01779.17 GAM18755.1 - 1.3e-18 67.0 10.9 1.3e-18 67.0 10.9 2.1 2 0 0 2 2 2 1 Ribosomal L29e protein family Integrase_Zn PF02022.19 GAM18755.1 - 0.6 10.1 5.4 26 4.9 0.0 2.4 2 0 0 2 2 2 0 Integrase Zinc binding domain Iso_dh PF00180.20 GAM18756.1 - 1.1e-77 261.5 0.0 1.3e-77 261.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 GAM18756.1 - 0.16 12.7 0.3 0.38 11.5 0.0 1.7 2 0 0 2 2 2 0 Phenylalanine zipper RabGAP-TBC PF00566.18 GAM18757.1 - 4e-57 193.3 0.3 4e-57 193.3 0.3 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RNase_P_p30 PF01876.16 GAM18758.1 - 4.5e-50 170.1 0.1 6.1e-50 169.7 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Antimicrobial14 PF08109.11 GAM18760.1 - 0.038 14.0 0.1 0.057 13.5 0.1 1.2 1 0 0 1 1 1 0 Lactocin 705 family Spc7 PF08317.11 GAM18761.1 - 0.0024 16.8 12.4 0.0024 16.8 12.4 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein Myosin_tail_1 PF01576.19 GAM18761.1 - 0.0035 15.2 14.3 0.0052 14.7 14.3 1.2 1 0 0 1 1 1 1 Myosin tail EMP24_GP25L PF01105.24 GAM18761.1 - 0.058 13.3 3.8 0.25 11.3 3.7 2.1 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD MscS_porin PF12795.7 GAM18761.1 - 0.16 11.5 16.8 0.37 10.3 3.8 2.5 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain KASH_CCD PF14662.6 GAM18761.1 - 0.42 10.4 18.9 1.3 8.8 8.0 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF489 PF04356.12 GAM18761.1 - 0.65 10.0 3.7 1.1 9.3 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) bZIP_1 PF00170.21 GAM18761.1 - 4.2 7.6 14.9 1.5 9.0 0.2 4.4 2 1 1 3 3 3 0 bZIP transcription factor YabA PF06156.13 GAM18761.1 - 4.2 8.1 22.5 0.31 11.7 5.6 3.2 4 1 1 5 5 3 0 Initiation control protein YabA CENP-H PF05837.12 GAM18761.1 - 4.4 7.7 16.7 1.2 9.6 7.6 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Phage_GP20 PF06810.11 GAM18761.1 - 5 6.9 21.4 5.9 6.7 15.1 3.4 1 1 2 3 3 3 0 Phage minor structural protein GP20 CCDC-167 PF15188.6 GAM18761.1 - 5.5 7.4 8.3 0.36 11.2 1.4 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Rootletin PF15035.6 GAM18761.1 - 5.8 6.9 19.8 2.1 8.3 14.7 2.4 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 GAM18761.1 - 9.8 6.2 23.5 1.2 9.2 15.2 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3209 PF11483.8 GAM18762.1 - 0.046 14.2 0.2 0.083 13.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) DUF1192 PF06698.11 GAM18762.1 - 1.2 9.2 5.2 0.48 10.5 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) RRM_1 PF00076.22 GAM18763.1 - 1.3e-09 37.7 1.1 4.5e-05 23.2 0.1 3.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM18763.1 - 0.0039 16.8 0.0 0.0082 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM176 PF14851.6 GAM18763.1 - 1.3 8.7 5.0 2.8 7.6 5.0 1.5 1 0 0 1 1 1 0 FAM176 family PPI_Ypi1 PF07491.11 GAM18764.1 - 9.1e-21 73.5 7.1 9.1e-21 73.5 7.1 1.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor Dicty_REP PF05086.12 GAM18764.1 - 0.23 9.4 4.7 0.25 9.3 4.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Atrophin-1 PF03154.15 GAM18764.1 - 2.6 6.2 7.0 2.7 6.1 7.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family TMEM119 PF15724.5 GAM18764.1 - 6.2 6.8 8.3 0.46 10.5 2.5 1.8 1 1 1 2 2 2 0 TMEM119 family Ras PF00071.22 GAM18765.1 - 2e-61 206.3 0.6 2.5e-61 206.0 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM18765.1 - 1.1e-34 119.2 0.1 1.7e-34 118.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM18765.1 - 8.4e-14 51.4 0.2 1e-13 51.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM18765.1 - 1.5e-07 31.4 0.1 2.5e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM18765.1 - 1.4e-06 28.3 0.1 0.0088 16.0 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAM18765.1 - 6.3e-06 25.9 0.1 3.7e-05 23.3 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAM18765.1 - 9.5e-05 22.8 0.0 0.00015 22.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 GAM18765.1 - 0.00044 19.7 0.1 0.00058 19.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM18765.1 - 0.00053 19.5 0.0 0.0009 18.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 GAM18765.1 - 0.004 17.4 0.1 0.034 14.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 GAM18765.1 - 0.012 15.1 0.3 0.061 12.9 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 GAM18765.1 - 0.014 15.1 0.1 0.031 14.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM18765.1 - 0.027 15.0 0.3 0.043 14.3 0.2 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 GAM18765.1 - 0.029 14.1 0.0 0.1 12.3 0.0 1.8 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SFTA2 PF15210.6 GAM18765.1 - 0.039 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Surfactant-associated protein 2 AAA_28 PF13521.6 GAM18765.1 - 0.045 14.0 0.5 0.37 11.0 0.5 2.1 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 GAM18765.1 - 0.049 13.0 0.0 0.13 11.6 0.0 1.7 3 0 0 3 3 3 0 Bacterial TniB protein KAP_NTPase PF07693.14 GAM18765.1 - 0.051 12.8 0.1 0.12 11.6 0.1 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.6 GAM18765.1 - 0.056 13.5 0.1 0.14 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 GAM18765.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 GAM18765.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 GAM18765.1 - 0.25 11.1 0.9 0.41 10.4 0.6 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Cofilin_ADF PF00241.20 GAM18766.1 - 1.3e-10 41.1 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Fer2_3 PF13085.6 GAM18767.1 - 2.9e-32 110.9 0.0 4.8e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 GAM18767.1 - 1.1e-08 35.4 2.2 1.1e-08 35.4 2.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAM18767.1 - 4.6e-08 33.4 7.2 6.7e-07 29.7 6.5 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAM18767.1 - 5.1e-08 32.9 1.3 5.1e-08 32.9 1.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 GAM18767.1 - 0.0085 16.3 1.6 0.21 11.8 0.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 GAM18767.1 - 0.022 14.7 5.1 0.028 14.4 0.4 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_16 PF13484.6 GAM18767.1 - 0.25 12.3 8.5 4.3 8.4 1.4 3.1 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 GAM18767.1 - 1.9 9.1 15.8 0.54 10.9 8.7 2.9 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAM18767.1 - 4.9 7.4 15.7 11 6.2 4.8 3.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain SUIM_assoc PF16619.5 GAM18768.1 - 0.39 10.8 28.9 0.73 9.9 0.0 3.9 2 2 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TraV PF09676.10 GAM18768.1 - 1.4 10.0 11.1 0.99 10.4 1.7 2.5 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) SR-25 PF10500.9 GAM18768.1 - 2.5 7.7 15.7 1.4 8.5 5.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Zw10 PF06248.13 GAM18769.1 - 2.6e-14 52.7 19.1 1.3e-07 30.6 1.2 2.7 1 1 0 2 2 2 2 Centromere/kinetochore Zw10 Vps26 PF03643.15 GAM18770.1 - 8.1e-90 300.5 10.2 1.1e-86 290.2 5.2 2.0 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 GAM18770.1 - 4.8e-05 23.5 0.5 0.5 10.4 0.1 3.1 2 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain tRNA-synt_2 PF00152.20 GAM18771.1 - 5.5e-101 337.8 0.0 7e-101 337.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAM18771.1 - 1.7e-10 40.7 0.0 3.7e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 GAM18771.1 - 1.3e-08 34.9 0.0 2.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 GAM18771.1 - 0.012 15.2 0.1 0.077 12.5 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Sporozoite_P67 PF05642.11 GAM18772.1 - 0.042 11.9 8.7 0.058 11.5 8.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen tify PF06200.14 GAM18772.1 - 0.05 12.9 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 tify domain DUF4803 PF16061.5 GAM18773.1 - 0.013 15.0 2.4 0.014 14.9 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) zf-CCCH PF00642.24 GAM18774.1 - 2e-13 49.9 40.9 0.0002 21.2 0.3 5.6 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAM18774.1 - 1e-10 41.3 51.2 2e-05 24.5 1.2 6.5 6 1 0 6 6 6 4 Zinc finger domain Torus PF16131.5 GAM18774.1 - 1.2e-07 32.4 45.6 0.00074 20.2 1.3 6.4 2 1 4 6 6 6 5 Torus domain zf-CCCH_4 PF18044.1 GAM18774.1 - 7.3e-07 28.8 34.1 0.00013 21.7 0.2 5.0 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCHC PF00098.23 GAM18774.1 - 1.4e-06 28.1 16.1 0.00049 20.0 2.2 3.7 3 0 0 3 3 3 2 Zinc knuckle zf-CCCH_3 PF15663.5 GAM18774.1 - 2.6e-06 27.6 9.0 2.6e-06 27.6 9.0 3.5 2 2 2 4 4 4 1 Zinc-finger containing family zf-CCHC_4 PF14392.6 GAM18774.1 - 0.0069 16.1 5.3 0.22 11.3 0.2 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 GAM18774.1 - 0.4 10.5 12.8 0.43 10.4 2.9 3.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCCH_2 PF14608.6 GAM18774.1 - 3.5 8.2 44.4 6.3 7.4 0.6 6.8 6 0 0 6 6 6 0 RNA-binding, Nab2-type zinc finger Ceramidase PF05875.12 GAM18775.1 - 4.9e-56 190.1 8.6 6e-56 189.8 8.6 1.1 1 0 0 1 1 1 1 Ceramidase DDHD PF02862.17 GAM18776.1 - 3.6e-26 92.7 0.0 5.6e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 DDHD domain DUF676 PF05057.14 GAM18776.1 - 0.017 14.7 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 GAM18776.1 - 0.041 13.1 0.3 0.22 10.7 0.0 2.1 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF727 PF05303.12 GAM18777.1 - 2.7e-23 82.0 0.0 3.1e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF727) ARTD15_N PF18084.1 GAM18778.1 - 1.7e-17 63.4 0.2 3.3e-17 62.5 0.2 1.5 1 0 0 1 1 1 1 ARTD15 N-terminal domain PARP PF00644.20 GAM18778.1 - 0.00038 20.1 0.2 0.00082 19.0 0.2 1.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Cellulase PF00150.18 GAM18779.1 - 1.2e-28 100.3 2.8 3.1e-28 99.0 2.8 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 GAM18779.1 - 5.6e-11 42.8 0.7 1e-10 42.0 0.7 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_42 PF02449.15 GAM18779.1 - 0.0014 18.1 0.2 0.0028 17.0 0.0 1.6 2 0 0 2 2 2 1 Beta-galactosidase PolyA_pol PF01743.20 GAM18780.1 - 2.3e-29 102.4 0.1 2.3e-29 102.4 0.1 2.0 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 GAM18780.1 - 6.1e-06 25.9 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 GAM18780.1 - 0.012 15.6 0.1 0.93 9.5 0.1 2.6 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Ribosomal_L23eN PF03939.13 GAM18781.1 - 8.1e-16 58.0 11.2 1.7e-15 56.9 11.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 GAM18781.1 - 1.1e-13 51.4 3.1 1.1e-13 51.4 3.1 2.6 2 2 0 2 2 2 1 Ribosomal protein L23 G-patch PF01585.23 GAM18782.1 - 4.6e-08 32.8 1.2 1.4e-07 31.3 1.2 1.8 1 0 0 1 1 1 1 G-patch domain SEP PF08059.13 GAM18783.1 - 1.5e-26 92.7 2.2 3.6e-26 91.6 0.1 2.5 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 GAM18783.1 - 8.7e-15 54.7 0.1 1.7e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 GAM18783.1 - 3.8e-14 52.2 0.2 7.4e-14 51.3 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 GAM18783.1 - 0.02 14.5 0.1 0.05 13.2 0.0 1.7 2 0 0 2 2 2 0 TAP C-terminal domain FAM199X PF15814.5 GAM18783.1 - 3.3 6.7 9.2 1.3 8.0 1.7 2.1 2 0 0 2 2 2 0 Protein family FAM199X Herpes_capsid PF06112.11 GAM18783.1 - 5.3 7.1 18.5 0.21 11.6 2.6 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Phospholamban PF04272.14 GAM18784.1 - 0.085 12.3 3.5 0.11 12.0 3.5 1.2 1 0 0 1 1 1 0 Phospholamban Coiled PF05710.12 GAM18785.1 - 5.1e-07 30.4 5.9 6.3e-07 30.1 5.9 1.1 1 0 0 1 1 1 1 Coiled coil MSSP PF03940.13 GAM18785.1 - 0.018 14.6 13.2 0.018 14.6 13.2 2.4 1 1 1 2 2 2 0 Male specific sperm protein ATG16 PF08614.11 GAM18787.1 - 0.0022 18.3 88.1 0.085 13.1 25.1 4.4 1 1 3 4 4 4 3 Autophagy protein 16 (ATG16) Filament PF00038.21 GAM18787.1 - 0.0056 16.3 40.5 0.0056 16.3 40.5 3.3 2 1 1 3 3 3 1 Intermediate filament protein DUF4407 PF14362.6 GAM18787.1 - 0.088 12.1 67.3 9.1 5.5 19.7 4.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 GAM18787.1 - 0.15 12.4 0.3 0.15 12.4 0.3 8.7 8 3 1 9 9 9 0 Csm1 N-terminal domain HOOK PF05622.12 GAM18787.1 - 0.17 10.0 86.8 0.011 14.0 21.5 4.1 3 1 1 4 4 4 0 HOOK protein HALZ PF02183.18 GAM18787.1 - 2.9 8.2 31.0 0.87 9.9 5.7 5.9 5 0 0 5 5 5 0 Homeobox associated leucine zipper Cellulase PF00150.18 GAM18788.1 - 0.0016 18.0 1.0 0.0024 17.4 1.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PWWP PF00855.17 GAM18789.1 - 2.7e-13 50.1 0.5 2.7e-13 50.1 0.5 3.1 3 0 0 3 3 3 1 PWWP domain BTB PF00651.31 GAM18790.1 - 1.6e-21 76.6 1.7 4.9e-19 68.6 0.3 2.4 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 GAM18790.1 - 1.2e-09 38.2 2.2 1.5e-07 31.4 0.8 3.1 2 1 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 GAM18790.1 - 0.00073 19.7 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain Cas_VVA1548 PF09652.10 GAM18790.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) DNA_pol_A PF00476.20 GAM18791.1 - 4.4e-101 338.6 1.9 4.4e-101 338.6 1.9 1.6 2 0 0 2 2 2 1 DNA polymerase family A TMEM210 PF15195.6 GAM18791.1 - 0.1 13.1 0.1 0.32 11.4 0.1 1.8 1 0 0 1 1 1 0 TMEM210 family Ras PF00071.22 GAM18793.1 - 1.7e-28 99.3 0.2 2.2e-28 98.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM18793.1 - 2.1e-22 79.6 0.0 3.1e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM18793.1 - 3.3e-15 56.0 0.1 4.1e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM18793.1 - 8.7e-08 31.9 0.0 2.2e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAM18793.1 - 1.2e-06 28.1 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM18793.1 - 0.00013 22.0 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM18793.1 - 0.015 15.2 0.1 0.088 12.7 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 GAM18793.1 - 0.031 13.7 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Dynamin_N PF00350.23 GAM18793.1 - 0.089 12.8 0.0 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 GAM18793.1 - 0.1 12.1 0.1 0.24 10.9 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Peptidase_M41 PF01434.18 GAM18794.1 - 2.1e-60 203.9 3.7 7.6e-60 202.0 3.7 1.9 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAM18794.1 - 3.8e-40 137.4 0.0 2.1e-39 135.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM18794.1 - 9.8e-10 38.1 0.0 2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 GAM18794.1 - 4.3e-05 23.3 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAM18794.1 - 7.1e-05 22.8 0.0 0.00036 20.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM18794.1 - 0.00012 22.5 0.1 0.033 14.6 0.1 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM18794.1 - 0.0011 19.2 1.5 0.38 11.0 0.1 3.7 1 1 2 4 4 4 1 AAA domain TIP49 PF06068.13 GAM18794.1 - 0.0013 18.0 0.0 0.003 16.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase PF06745.13 GAM18794.1 - 0.0022 17.4 2.7 0.24 10.7 0.1 3.2 2 1 0 3 3 3 1 KaiC AAA_24 PF13479.6 GAM18794.1 - 0.0079 15.9 0.3 3.4 7.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 GAM18794.1 - 0.014 15.1 0.0 0.041 13.6 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 GAM18794.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GAM18794.1 - 0.02 14.6 0.1 0.079 12.7 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 GAM18794.1 - 0.028 14.3 0.2 0.45 10.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 GAM18794.1 - 0.029 13.7 0.1 0.065 12.5 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 GAM18794.1 - 0.038 13.4 0.1 0.093 12.1 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 GAM18794.1 - 0.041 14.0 0.0 0.2 11.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 GAM18794.1 - 0.044 13.3 0.0 0.31 10.5 0.0 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region PDCD2_C PF04194.13 GAM18794.1 - 0.082 13.0 0.3 0.16 12.0 0.3 1.4 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain SecA_DEAD PF07517.14 GAM18794.1 - 0.09 12.0 0.2 0.29 10.4 0.1 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_14 PF13173.6 GAM18794.1 - 0.1 12.6 0.0 0.44 10.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain Beta_helix PF13229.6 GAM18795.1 - 6.9e-54 182.0 94.5 1.4e-23 83.5 27.6 3.7 2 1 3 5 5 5 4 Right handed beta helix region NosD PF05048.13 GAM18795.1 - 2.9e-26 92.2 56.0 4.3e-15 55.6 17.9 3.6 2 1 2 4 4 4 3 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 GAM18795.1 - 4.4e-05 23.3 0.6 0.0001 22.1 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM18795.1 - 5.8e-05 22.9 0.9 5.8e-05 22.9 0.9 1.7 2 0 0 2 2 2 1 F-box domain Pectate_lyase_3 PF12708.7 GAM18795.1 - 0.00071 19.5 30.9 0.017 15.0 7.6 3.9 1 1 2 3 3 3 3 Pectate lyase superfamily protein Hamartin PF04388.12 GAM18795.1 - 0.29 9.7 7.9 0.44 9.2 7.9 1.1 1 0 0 1 1 1 0 Hamartin protein RGS-like PF09128.11 GAM18796.1 - 0.063 13.0 0.9 0.12 12.1 0.7 1.6 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain ILEI PF15711.5 GAM18796.1 - 0.073 13.5 0.1 0.28 11.7 0.0 1.9 1 1 0 2 2 2 0 Interleukin-like EMT inducer Ninjurin PF04923.12 GAM18796.1 - 1.9 8.5 7.6 1.1 9.2 1.5 2.4 1 1 1 2 2 2 0 Ninjurin 7tm_1 PF00001.21 GAM18796.1 - 2.8 7.2 7.1 3 7.1 6.0 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Neugrin PF06413.11 GAM18797.1 - 3.7e-10 40.2 1.3 3.7e-10 40.2 1.3 3.1 2 2 1 3 3 3 1 Neugrin MRP-L20 PF12824.7 GAM18797.1 - 1.8e-05 25.0 6.6 1.8e-05 25.0 6.6 2.9 2 1 1 3 3 3 1 Mitochondrial ribosomal protein subunit L20 O-antigen_lig PF13425.6 GAM18797.1 - 5.7 5.6 5.5 7.6 5.2 5.5 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Dynactin_p62 PF05502.13 GAM18798.1 - 1.5e-29 103.1 22.5 4e-29 101.7 22.4 1.6 1 1 0 1 1 1 1 Dynactin p62 family PHA_synth_III_E PF09712.10 GAM18798.1 - 0.33 10.0 7.3 0.32 10.0 6.4 1.4 1 1 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Fe-S_biosyn PF01521.20 GAM18799.1 - 1.2e-15 57.7 0.0 1.5e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Voltage_CLC PF00654.20 GAM18800.1 - 7.2e-108 361.0 21.5 5.3e-107 358.1 17.2 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 GAM18800.1 - 2.4e-20 72.7 0.1 1.3e-09 38.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain TSP_3 PF02412.18 GAM18801.1 - 3.8 7.3 28.0 13 5.6 10.0 4.3 1 1 2 3 3 3 0 Thrombospondin type 3 repeat TSP_3 PF02412.18 GAM18802.1 - 0.0054 16.4 39.0 0.37 10.5 0.6 5.8 1 1 4 5 5 5 4 Thrombospondin type 3 repeat tRNA-synt_2b PF00587.25 GAM18804.1 - 0.021 14.8 0.4 0.03 14.3 0.4 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) HATPase_c PF02518.26 GAM18805.1 - 9.1e-32 109.9 0.1 1.8e-31 109.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM18805.1 - 1e-23 83.7 0.0 7.6e-23 80.8 0.0 2.6 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAM18805.1 - 2.5e-14 53.1 0.0 5.6e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 GAM18805.1 - 0.018 14.8 0.0 0.057 13.3 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_25 PF13649.6 GAM18805.1 - 0.15 12.8 0.0 2 9.2 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain DUF3311 PF11755.8 GAM18806.1 - 1.5 8.9 15.1 0.056 13.4 3.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) Methyltransf_10 PF05971.12 GAM18807.1 - 2.3e-53 181.5 0.6 9.8e-51 172.9 0.1 3.2 2 1 0 2 2 2 1 RNA methyltransferase MTS PF05175.14 GAM18807.1 - 5.1e-08 32.7 1.0 1.7e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 GAM18807.1 - 0.0019 17.7 0.1 0.0019 17.7 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 GAM18807.1 - 0.0052 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 GAM18807.1 - 0.012 15.6 0.1 0.032 14.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain TrmK PF04816.12 GAM18807.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase TPR_1 PF00515.28 GAM18808.1 - 7.2e-16 57.2 4.1 6.2e-05 22.6 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM18808.1 - 1.6e-13 49.6 1.3 0.00082 19.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM18808.1 - 2.2e-07 30.4 0.1 0.02 14.5 0.1 3.5 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 GAM18808.1 - 2.9e-07 30.1 3.8 0.0014 18.7 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat zf-RING_5 PF14634.6 GAM18808.1 - 4.1e-07 29.8 14.4 1e-06 28.6 14.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAM18808.1 - 5.2e-07 29.4 14.9 1.5e-06 28.0 14.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM18808.1 - 6.2e-07 29.2 15.6 1.5e-06 27.9 15.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM18808.1 - 2.3e-06 27.4 10.9 5.9e-06 26.0 10.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.6 GAM18808.1 - 3.4e-06 27.2 2.7 0.03 14.6 0.1 3.0 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM18808.1 - 6e-06 26.3 0.4 0.28 11.7 0.2 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM18808.1 - 1.5e-05 25.1 2.0 3.2e-05 24.1 2.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_2 PF13639.6 GAM18808.1 - 2.2e-05 24.7 14.7 5e-05 23.5 14.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAM18808.1 - 2.8e-05 24.0 8.5 2.8e-05 24.0 8.5 2.4 1 1 1 2 2 2 1 RING-type zinc-finger NARP1 PF12569.8 GAM18808.1 - 3.9e-05 22.8 0.5 3.9e-05 22.8 0.5 1.7 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 zf-C3HC4_4 PF15227.6 GAM18808.1 - 0.0012 19.0 16.2 0.0026 17.9 16.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAM18808.1 - 0.0014 18.4 7.9 0.0027 17.5 7.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein TPR_19 PF14559.6 GAM18808.1 - 0.0044 17.5 0.0 0.51 10.9 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM18808.1 - 0.011 16.4 0.0 6 7.6 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 GAM18808.1 - 0.046 13.6 15.5 0.88 9.5 16.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TPR_9 PF13371.6 GAM18808.1 - 0.091 12.9 0.3 0.2 11.8 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM18808.1 - 0.18 12.5 3.6 8.5 7.3 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 GAM18808.1 - 0.26 11.1 12.7 0.96 9.3 12.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3808 PF10300.9 GAM18808.1 - 1 8.0 7.4 0.066 11.9 1.7 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3808) zf-rbx1 PF12678.7 GAM18808.1 - 1.8 8.9 12.7 34 4.8 12.7 2.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain RecR PF02132.15 GAM18808.1 - 7.3 6.3 13.7 1.1 8.9 0.5 2.8 3 0 0 3 3 2 0 RecR protein PAT1 PF09770.9 GAM18808.1 - 7.8 4.6 24.2 9.4 4.4 24.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RasGAP PF00616.19 GAM18809.1 - 2.4e-45 154.8 0.3 2.4e-45 154.8 0.3 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAM18809.1 - 6.3e-18 65.2 3.1 6.3e-18 65.2 3.1 2.1 2 0 0 2 2 2 1 RasGAP C-terminus MCM_N PF14551.6 GAM18809.1 - 0.0037 17.8 0.1 0.025 15.2 0.1 2.5 1 0 0 1 1 1 1 MCM N-terminal domain Sec63 PF02889.16 GAM18810.1 - 1.1e-136 454.0 9.0 1.8e-77 260.0 1.8 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GAM18810.1 - 1.5e-53 181.2 0.9 2.5e-28 99.0 0.7 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 GAM18810.1 - 5.8e-27 94.8 1.0 3.5e-14 53.1 0.2 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM18810.1 - 1.7e-19 70.2 0.1 3.7e-08 33.7 0.0 3.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAM18810.1 - 1e-05 25.8 1.8 0.087 13.1 0.2 4.1 3 2 0 3 3 3 2 AAA domain AAA PF00004.29 GAM18810.1 - 5.6e-05 23.6 2.5 0.11 12.9 0.0 4.2 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 GAM18810.1 - 7.3e-05 22.3 0.0 0.29 10.6 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.6 GAM18810.1 - 0.00011 22.5 0.5 0.077 13.3 0.3 3.0 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 GAM18810.1 - 0.00036 20.7 0.0 0.0015 18.7 0.0 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain T2SSE PF00437.20 GAM18810.1 - 0.00042 19.5 0.0 1 8.3 0.0 2.8 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 GAM18810.1 - 0.0007 19.2 0.0 0.45 10.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAM18810.1 - 0.003 17.1 0.0 3 7.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAM18810.1 - 0.043 13.5 2.7 1.9 8.2 0.0 3.5 5 0 0 5 5 5 0 IstB-like ATP binding protein TniB PF05621.11 GAM18810.1 - 0.13 11.6 2.4 11 5.4 0.1 3.7 3 0 0 3 3 3 0 Bacterial TniB protein Erg28 PF03694.13 GAM18811.1 - 1.3e-28 99.6 5.6 1.5e-28 99.4 5.6 1.0 1 0 0 1 1 1 1 Erg28 like protein LIM PF00412.22 GAM18812.1 - 4.3e-22 78.1 35.6 9.8e-08 32.1 7.2 3.4 3 0 0 3 3 3 3 LIM domain C1_1 PF00130.22 GAM18812.1 - 0.041 13.8 23.9 0.23 11.3 1.6 3.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) XAF1_C PF18608.1 GAM18812.1 - 0.053 13.1 8.9 2.3 7.8 0.9 3.5 3 0 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain MTHFR_C PF12225.8 GAM18812.1 - 0.51 10.0 19.4 1.8 8.3 0.2 4.2 3 2 0 3 3 3 0 Methylene-tetrahydrofolate reductase C terminal ETF_QO PF05187.13 GAM18812.1 - 1.6 8.9 14.6 11 6.2 2.1 3.5 3 0 0 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S PHF5 PF03660.14 GAM18812.1 - 1.7 8.9 20.7 1.5 9.1 0.8 3.3 3 0 0 3 3 3 0 PHF5-like protein Peptidase_S28 PF05577.12 GAM18813.1 - 1.5e-92 310.7 6.1 1.9e-92 310.4 6.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.7 GAM18813.1 - 0.039 14.6 0.1 0.085 13.4 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family TIG PF01833.24 GAM18814.1 - 7.4e-14 51.6 22.5 2.4e-06 27.5 0.9 6.0 6 0 0 6 6 6 3 IPT/TIG domain Lectin_C PF00059.21 GAM18814.1 - 0.00028 21.6 2.1 0.00083 20.1 2.1 1.9 1 0 0 1 1 1 1 Lectin C-type domain EGF_2 PF07974.13 GAM18814.1 - 0.0019 18.6 6.1 0.0041 17.5 6.1 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 GAM18814.1 - 0.055 13.5 5.3 0.15 12.2 5.3 1.7 1 0 0 1 1 1 0 Tenascin EGF domain I-EGF_1 PF18372.1 GAM18814.1 - 0.17 12.0 3.3 0.43 10.7 3.3 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Insulin_TMD PF17870.1 GAM18814.1 - 0.22 11.6 1.5 0.65 10.1 1.5 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Laminin_EGF PF00053.24 GAM18814.1 - 0.57 10.4 2.5 1.5 9.0 2.5 1.7 1 0 0 1 1 1 0 Laminin EGF domain Baculo_PEP_C PF04513.12 GAM18815.1 - 0.0035 17.4 5.0 0.22 11.5 3.9 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2254 PF10011.9 GAM18815.1 - 0.019 13.8 0.2 0.022 13.6 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) ICAT PF06384.11 GAM18815.1 - 0.02 15.2 0.1 0.032 14.5 0.1 1.4 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Melittin PF01372.17 GAM18815.1 - 0.85 9.7 4.8 23 5.2 0.0 3.8 3 1 2 5 5 5 0 Melittin Peptidase_S9 PF00326.21 GAM18816.1 - 0.0014 18.1 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAM18816.1 - 0.0065 17.1 2.5 0.017 15.7 2.5 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM18816.1 - 0.058 12.7 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 GAM18816.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF1084 PF06454.11 GAM18817.1 - 1.1e-09 38.1 22.7 2e-09 37.2 22.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Methyltr_RsmB-F PF01189.17 GAM18818.1 - 1.8e-37 128.9 0.0 1.4e-36 126.0 0.0 2.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 GAM18818.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase AMNp_N PF10423.9 GAM18818.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus Dicty_REP PF05086.12 GAM18818.1 - 0.74 7.7 9.0 0.1 10.6 0.5 2.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein eIF-5_eIF-2B PF01873.17 GAM18819.1 - 5e-38 129.6 0.5 1e-37 128.6 0.5 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 GAM18819.1 - 0.0076 15.7 0.7 0.016 14.7 0.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Macoilin PF09726.9 GAM18819.1 - 0.045 12.3 18.9 0.052 12.1 18.9 1.1 1 0 0 1 1 1 0 Macoilin family Cwf_Cwc_15 PF04889.12 GAM18819.1 - 0.18 11.5 24.9 0.24 11.1 24.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ndc1_Nup PF09531.10 GAM18819.1 - 0.31 9.7 10.0 0.39 9.3 10.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF5427 PF10310.9 GAM18819.1 - 1.5 7.7 25.2 2 7.3 25.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Arc_trans_TRASH PF08394.10 GAM18819.1 - 1.9 8.9 5.9 3.7 8.0 2.3 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain Mitofilin PF09731.9 GAM18819.1 - 5 5.9 29.7 6.1 5.6 29.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SOBP PF15279.6 GAM18819.1 - 6.8 7.2 14.1 9.8 6.7 14.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein MDM1 PF15501.6 GAM18819.1 - 7.2 5.6 32.7 9.9 5.2 32.7 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Hydrolase_4 PF12146.8 GAM18820.1 - 8.9e-21 74.2 0.0 7.4e-14 51.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM18820.1 - 5e-17 62.4 0.1 4.1e-11 43.0 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM18820.1 - 4.1e-08 33.0 0.0 5.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAM18820.1 - 3.5e-07 30.3 0.2 0.024 14.5 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF818 PF05677.12 GAM18820.1 - 1.3e-06 27.6 0.0 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.7 GAM18820.1 - 2e-06 28.6 0.0 3.5e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 GAM18820.1 - 0.00065 19.3 0.0 0.01 15.4 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 GAM18820.1 - 0.0017 17.1 0.0 0.18 10.4 0.0 2.7 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 GAM18820.1 - 0.0019 18.1 0.0 0.0073 16.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 GAM18820.1 - 0.0026 17.7 0.0 1.4 8.7 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 GAM18820.1 - 0.0072 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S28 PF05577.12 GAM18820.1 - 0.02 13.7 0.0 0.039 12.8 0.0 1.4 1 1 0 1 1 1 0 Serine carboxypeptidase S28 LIDHydrolase PF10230.9 GAM18820.1 - 0.039 13.5 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF1749 PF08538.10 GAM18820.1 - 0.057 12.5 0.0 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_4 PF08386.10 GAM18820.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein UPF0227 PF05728.12 GAM18820.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 GAM18820.1 - 0.081 12.6 0.0 0.23 11.2 0.0 1.7 2 1 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 GAM18820.1 - 0.091 12.9 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.25 GAM18820.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 GAM18820.1 - 0.18 11.6 0.0 22 4.8 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family TPR_2 PF07719.17 GAM18821.1 - 3.1e-16 58.1 0.7 0.0027 17.7 0.0 5.7 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM18821.1 - 5.1e-13 49.1 3.0 0.006 16.9 0.0 5.3 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM18821.1 - 1.8e-12 46.5 6.7 0.0073 16.1 0.0 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM18821.1 - 6.4e-09 35.3 9.4 0.016 15.4 0.0 5.4 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM18821.1 - 1.1e-08 34.9 2.9 0.6 10.6 0.0 6.0 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM18821.1 - 2.4e-07 31.2 0.1 0.00036 21.0 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM18821.1 - 9.6e-07 29.1 0.1 0.29 12.1 0.0 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM18821.1 - 1.5e-06 27.7 0.1 0.3 10.8 0.0 4.9 5 0 0 5 5 5 2 TPR repeat TPR_7 PF13176.6 GAM18821.1 - 0.00013 21.7 1.5 7 6.9 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM18821.1 - 0.00048 20.6 3.6 0.68 10.7 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM18821.1 - 0.0038 16.5 1.1 1.9 7.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM18821.1 - 0.008 16.3 0.1 0.64 10.2 0.2 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 GAM18821.1 - 0.062 13.4 5.7 15 5.7 0.0 4.3 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain ALMT PF11744.8 GAM18821.1 - 0.63 8.8 8.5 2.8 6.7 1.0 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter FAM60A PF15396.6 GAM18821.1 - 3.6 7.5 7.4 3.3 7.7 1.0 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Coilin_N PF15862.5 GAM18821.1 - 4.5 7.1 14.8 0.13 12.0 4.0 2.6 2 0 0 2 2 2 0 Coilin N-terminus Pkinase_Tyr PF07714.17 GAM18822.1 - 9.7e-56 188.9 0.0 1.3e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM18822.1 - 8.1e-51 172.9 0.1 1.1e-50 172.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 GAM18822.1 - 0.00011 21.6 0.2 0.00017 21.0 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MRI PF15325.6 GAM18822.1 - 0.45 11.6 6.4 0.24 12.5 0.5 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection GDI PF00996.18 GAM18823.1 - 1.2e-216 719.3 2.1 1.5e-216 719.0 2.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 GAM18823.1 - 0.00074 18.9 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Citrate_synt PF00285.21 GAM18824.1 - 1.4e-137 458.6 0.0 2.2e-137 458.0 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain LIM PF00412.22 GAM18825.1 - 3.7e-19 68.7 22.9 1.5e-11 44.4 5.8 3.0 3 0 0 3 3 3 2 LIM domain PH PF00169.29 GAM18825.1 - 4.4e-07 30.3 0.0 1.5e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 PH domain SPX PF03105.19 GAM18825.1 - 0.0054 16.7 5.6 0.51 10.2 5.6 2.3 1 1 0 1 1 1 1 SPX domain DUF2321 PF10083.9 GAM18825.1 - 8.8 5.9 12.1 8.1 6.1 5.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Ank_2 PF12796.7 GAM18826.1 - 0.00032 21.2 0.6 0.0064 17.1 0.1 3.4 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM18826.1 - 0.064 13.6 0.2 3.1 8.2 0.1 3.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM18826.1 - 0.077 13.6 3.9 4.2 8.2 0.0 5.4 7 0 0 7 7 7 0 Ankyrin repeat Prefoldin_2 PF01920.20 GAM18827.1 - 4.2e-22 78.1 0.3 4.8e-22 77.9 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit OmpH PF03938.14 GAM18827.1 - 0.003 17.9 1.5 1 9.7 0.0 2.1 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) DUF1907 PF08925.11 GAM18827.1 - 0.0059 16.1 0.4 0.0072 15.8 0.4 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) Prefoldin PF02996.17 GAM18827.1 - 0.011 15.6 1.0 0.62 10.0 0.0 2.1 1 1 1 2 2 2 0 Prefoldin subunit CASP_C PF08172.12 GAM18827.1 - 0.013 14.9 0.4 0.015 14.7 0.4 1.1 1 0 0 1 1 1 0 CASP C terminal Nsp1_C PF05064.13 GAM18827.1 - 0.037 13.8 2.3 2.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region ArsR PF09824.9 GAM18827.1 - 0.085 12.4 0.8 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 ArsR transcriptional regulator Seryl_tRNA_N PF02403.22 GAM18827.1 - 0.12 12.6 4.1 5.1 7.4 0.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 GAM18827.1 - 0.21 11.9 5.3 0.48 10.8 2.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DEAD PF00270.29 GAM18828.1 - 4.7e-18 65.6 0.0 9.7e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM18828.1 - 1.2e-15 57.8 0.0 6.1e-15 55.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 GAM18828.1 - 0.001 19.8 0.1 0.0029 18.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) T2SSE PF00437.20 GAM18828.1 - 0.065 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein BNIP2 PF12496.8 GAM18828.1 - 3.1 8.2 9.7 24 5.4 9.6 2.6 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Cast PF10174.9 GAM18829.1 - 0.00059 18.2 20.6 0.00079 17.8 20.6 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Atg14 PF10186.9 GAM18829.1 - 0.0098 15.0 20.3 0.012 14.7 20.3 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 CLPTM1 PF05602.12 GAM18829.1 - 0.021 13.9 12.1 0.026 13.6 12.1 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Sec62 PF03839.16 GAM18829.1 - 0.026 14.1 11.8 0.038 13.5 11.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Lin-8 PF03353.15 GAM18829.1 - 0.035 13.7 19.0 0.042 13.4 19.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF572 PF04502.13 GAM18829.1 - 0.045 13.4 10.3 0.043 13.4 10.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DDRGK PF09756.9 GAM18829.1 - 0.086 12.4 20.6 0.11 12.1 20.6 1.1 1 0 0 1 1 1 0 DDRGK domain SpoIIP PF07454.11 GAM18829.1 - 0.097 12.1 11.9 0.16 11.4 11.9 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 GAM18829.1 - 0.13 11.2 15.2 0.14 11.1 15.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 GAM18829.1 - 0.2 9.9 27.0 0.21 9.8 27.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF812 PF05667.11 GAM18829.1 - 0.2 10.5 26.2 0.26 10.1 26.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TFIIA PF03153.13 GAM18829.1 - 0.3 11.1 36.5 0.37 10.7 36.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PDDEXK_6 PF04720.12 GAM18829.1 - 0.32 10.9 8.3 0.45 10.4 8.3 1.3 1 0 0 1 1 1 0 PDDEXK-like family of unknown function CLN3 PF02487.17 GAM18829.1 - 0.4 9.7 7.6 0.47 9.5 7.6 1.2 1 0 0 1 1 1 0 CLN3 protein FUSC PF04632.12 GAM18829.1 - 0.42 9.1 12.2 0.51 8.8 12.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ndc1_Nup PF09531.10 GAM18829.1 - 0.62 8.7 8.9 0.68 8.6 8.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDHD PF02862.17 GAM18829.1 - 0.93 9.6 9.6 0.22 11.6 6.4 1.7 2 0 0 2 2 2 0 DDHD domain PPL5 PF18168.1 GAM18829.1 - 1 8.6 8.6 1.3 8.2 8.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Membralin PF09746.9 GAM18829.1 - 1.2 8.1 9.4 1.4 7.9 9.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF2477 PF10631.9 GAM18829.1 - 1.2 9.8 10.3 1.6 9.4 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) UPF0560 PF10577.9 GAM18829.1 - 1.9 6.9 20.7 2.2 6.7 20.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Band_3_cyto PF07565.13 GAM18829.1 - 1.9 8.3 13.5 2.8 7.7 13.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hydin_ADK PF17213.3 GAM18829.1 - 2 8.7 10.6 2.7 8.2 10.6 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Gti1_Pac2 PF09729.9 GAM18829.1 - 2 8.5 0.0 2 8.5 0.0 2.1 1 1 1 2 2 2 0 Gti1/Pac2 family PepSY_TM PF03929.16 GAM18829.1 - 2.2 7.9 5.4 2.7 7.6 5.4 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF4192 PF13830.6 GAM18829.1 - 2.3 8.2 4.0 3 7.8 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) FAM76 PF16046.5 GAM18829.1 - 2.4 7.4 18.7 2.5 7.4 17.9 1.4 2 0 0 2 2 1 0 FAM76 protein Zip PF02535.22 GAM18829.1 - 2.5 7.2 4.3 2.6 7.2 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PTPRCAP PF15713.5 GAM18829.1 - 2.7 8.3 16.7 3.9 7.8 16.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4484 PF14831.6 GAM18829.1 - 2.9 7.9 12.2 3.9 7.4 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Tim54 PF11711.8 GAM18829.1 - 3.3 6.4 15.3 4.3 6.0 15.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 GAM18829.1 - 3.6 6.3 17.2 4.2 6.0 17.2 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 GAM18829.1 - 4.2 7.3 11.8 6 6.8 11.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CAF1 PF04857.20 GAM18829.1 - 4.5 6.4 10.0 5.2 6.1 10.0 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease DUF3292 PF11696.8 GAM18829.1 - 4.9 5.4 12.4 6.2 5.1 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) MMPL PF03176.15 GAM18829.1 - 4.9 6.0 6.7 7.1 5.4 6.7 1.2 1 0 0 1 1 1 0 MMPL family BT1 PF03092.16 GAM18829.1 - 5.2 5.2 6.5 6.9 4.8 6.5 1.1 1 0 0 1 1 1 0 BT1 family Het-C PF07217.11 GAM18829.1 - 6 5.3 12.0 6.9 5.1 12.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C V_ATPase_I PF01496.19 GAM18829.1 - 6.3 4.6 16.2 8.6 4.1 16.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GPO PF05929.11 GAM18829.1 - 7.2 6.2 24.0 9.4 5.8 24.0 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Neur_chan_memb PF02932.16 GAM18829.1 - 7.2 6.6 12.8 9.2 6.3 12.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Exonuc_VII_L PF02601.15 GAM18829.1 - 7.5 6.0 22.1 9.5 5.7 22.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2828 PF11443.8 GAM18829.1 - 8.6 4.3 14.5 10 4.1 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MMR1 PF08505.10 GAM18829.1 - 9.6 6.4 19.0 15 5.8 19.0 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein ALMT PF11744.8 GAM18829.1 - 9.8 4.9 12.1 12 4.5 12.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Acetyltransf_4 PF13420.7 GAM18831.1 - 2e-19 70.2 1.1 2.2e-12 47.4 0.2 2.0 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAM18831.1 - 3.3e-08 34.3 0.0 4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM18831.1 - 7e-08 32.7 0.0 9.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM18831.1 - 0.00053 20.4 0.0 0.00079 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM18831.1 - 0.0054 16.7 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF1374 PF07118.11 GAM18831.1 - 0.055 14.0 0.0 1.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) EamA PF00892.20 GAM18833.1 - 4.4e-41 140.3 34.1 8.4e-24 84.3 11.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 GAM18833.1 - 0.0001 21.5 0.5 0.0076 15.4 0.1 2.4 2 0 0 2 2 2 2 Magnesium transporter NIPA CRT-like PF08627.10 GAM18833.1 - 0.0029 16.6 6.9 0.047 12.6 0.2 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like RRN3 PF05327.11 GAM18833.1 - 0.9 8.0 6.7 1.4 7.4 6.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BK_channel_a PF03493.18 GAM18834.1 - 8.6e-22 77.2 0.0 6.7e-21 74.3 0.0 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Presenilin PF01080.17 GAM18835.1 - 1.5 7.5 9.6 1.3 7.7 2.8 2.1 2 0 0 2 2 2 0 Presenilin CDC45 PF02724.14 GAM18835.1 - 6.8 4.8 13.0 0.96 7.7 2.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Trypan_PARP PF05887.11 GAM18835.1 - 8.3 6.4 8.7 0.47 10.4 1.5 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) FG-GAP_2 PF14312.6 GAM18836.1 - 6.2e-05 23.2 1.2 0.052 13.8 0.1 4.1 5 0 0 5 5 5 2 FG-GAP repeat Ephrin_rec_like PF07699.13 GAM18836.1 - 0.091 12.5 9.3 0.85 9.4 9.2 2.6 1 1 0 1 1 1 0 Putative ephrin-receptor like Cnd1_N PF12922.7 GAM18837.1 - 0.088 12.7 3.0 0.084 12.7 0.9 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term CCDC24 PF15669.5 GAM18837.1 - 0.81 9.5 12.3 18 5.1 0.0 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 24 family RAP1 PF07218.11 GAM18837.1 - 3.7 5.7 27.6 1.4 7.1 0.8 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Beta_helix PF13229.6 GAM18838.1 - 1.5e-10 41.2 55.1 0.00029 20.7 7.5 4.4 1 1 3 5 5 5 5 Right handed beta helix region Ank_4 PF13637.6 GAM18840.1 - 1.4e-41 140.3 9.7 2.6e-05 24.7 0.1 10.1 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM18840.1 - 2.7e-41 140.1 7.0 6.5e-09 36.3 0.1 6.9 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM18840.1 - 2.5e-39 132.8 11.9 0.00017 21.8 0.0 13.7 4 3 10 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM18840.1 - 3.2e-21 73.2 3.5 6 7.8 0.0 13.4 12 3 3 15 15 15 3 Ankyrin repeat DUF5049 PF16468.5 GAM18840.1 - 5.5e-11 42.2 9.5 0.86 9.6 0.0 11.2 11 3 4 15 15 15 3 Domain of unknown function (DUF5049) Ank PF00023.30 GAM18840.1 - 6.3e-08 32.7 2.7 24 5.6 0.1 8.9 5 4 3 8 8 8 1 Ankyrin repeat Ret2_MD PF18528.1 GAM18840.1 - 0.0038 17.6 0.1 84 3.6 0.0 4.5 2 2 5 7 7 7 0 RNA editing 3' terminal uridylyl transferase 2 middle domain SNF5 PF04855.12 GAM18841.1 - 2.6e-34 119.1 0.8 1.7e-17 64.0 0.0 3.7 2 2 0 3 3 3 2 SNF5 / SMARCB1 / INI1 Macoilin PF09726.9 GAM18841.1 - 0.97 7.9 14.2 1.3 7.5 14.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF3439 PF11921.8 GAM18841.1 - 1.6 8.7 4.8 3.5 7.6 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAM18841.1 - 9.4 6.2 14.7 2.4 8.2 8.3 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Ras PF00071.22 GAM18842.1 - 0.00026 20.6 0.0 0.00052 19.6 0.0 1.5 1 0 0 1 1 1 1 Ras family UreE_C PF05194.12 GAM18842.1 - 0.88 10.1 23.2 1 9.9 6.8 3.3 3 0 0 3 3 3 0 UreE urease accessory protein, C-terminal domain PAS PF00989.25 GAM18842.1 - 1.8 8.6 6.0 0.79 9.7 0.6 2.4 2 0 0 2 2 2 0 PAS fold Ras PF00071.22 GAM18843.1 - 1.2e-07 31.5 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM18843.1 - 1.7e-07 31.5 0.0 2.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM18843.1 - 0.013 14.9 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_28 PF13521.6 GAM18843.1 - 0.041 14.1 0.0 0.051 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain GbpA_2 PF18416.1 GAM18843.1 - 0.045 14.1 0.1 0.079 13.3 0.1 1.3 1 0 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 TMEM215 PF15746.5 GAM18843.1 - 0.05 13.1 0.1 0.1 12.1 0.0 1.5 1 1 1 2 2 2 0 TMEM215 family AAA_7 PF12775.7 GAM18843.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 GAM18843.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 GAM18843.1 - 0.19 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Alpha_GJ PF03229.13 GAM18843.1 - 0.73 10.4 8.3 0.46 11.1 0.4 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J GRAM PF02893.20 GAM18844.1 - 3.8e-08 33.2 0.7 8.5e-06 25.6 0.1 2.6 2 0 0 2 2 2 2 GRAM domain Caskin1-CID PF16600.5 GAM18844.1 - 0.018 15.6 3.3 0.018 15.6 3.3 4.8 4 1 1 5 5 5 0 Caskin1 CASK-interaction domain Ferlin_C PF16165.5 GAM18844.1 - 0.44 10.5 5.6 1.8 8.5 2.3 2.4 2 0 0 2 2 2 0 Ferlin C-terminus RNB PF00773.19 GAM18845.1 - 3.7e-56 190.8 5.8 6.3e-56 190.1 5.8 1.4 1 0 0 1 1 1 1 RNB domain SUIM_assoc PF16619.5 GAM18845.1 - 0.0045 17.0 1.4 0.0045 17.0 1.4 3.4 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Curlin_rpt PF07012.12 GAM18846.1 - 0.0041 17.1 0.4 0.33 11.0 0.1 2.5 3 0 0 3 3 3 2 Curlin associated repeat Mtc PF03820.17 GAM18850.1 - 3.2e-115 384.5 0.7 3.6e-115 384.3 0.7 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Med15_fungi PF05397.12 GAM18851.1 - 0.003 17.8 0.6 0.008 16.4 0.6 1.8 1 0 0 1 1 1 1 Mediator complex subunit 15 SUIM_assoc PF16619.5 GAM18851.1 - 0.14 12.3 11.9 0.57 10.3 0.5 3.4 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 GAM18852.1 - 1.3e-07 32.2 2.7 2.5 9.1 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM18852.1 - 7.9e-07 29.3 0.0 0.88 9.9 0.0 4.0 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Exonuc_VII_L PF02601.15 GAM18852.1 - 0.19 11.3 7.2 0.29 10.6 7.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit 60KD_IMP PF02096.20 GAM18852.1 - 0.22 11.4 3.8 0.34 10.8 3.8 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein TERB2 PF15101.6 GAM18852.1 - 0.34 10.9 5.7 0.67 10.0 5.7 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2722 PF10846.8 GAM18852.1 - 0.82 8.5 14.2 1.1 8.1 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 GAM18852.1 - 3.4 7.6 21.2 4.9 7.0 21.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sulfatase_C PF14707.6 GAM18852.1 - 4.3 8.1 6.7 11 6.7 6.7 1.7 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase RmuC PF02646.16 GAM18852.1 - 7.1 5.7 14.1 12 4.9 14.0 1.4 1 1 0 1 1 1 0 RmuC family USP8_interact PF08941.10 GAM18852.1 - 8.2 6.2 10.6 14 5.4 10.6 1.4 1 0 0 1 1 1 0 USP8 interacting Lipase_3 PF01764.25 GAM18853.1 - 1e-10 41.6 0.0 2.2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF4373 PF14297.6 GAM18853.1 - 0.02 15.7 0.3 2.1 9.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4373) DUF2974 PF11187.8 GAM18853.1 - 0.024 14.2 0.2 0.068 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) GST_C PF00043.25 GAM18854.1 - 6.8e-12 45.4 0.0 1.1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM18854.1 - 4.7e-09 36.5 0.0 3.1e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM18854.1 - 2.1e-07 31.0 0.0 3.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM18854.1 - 7.9e-07 29.3 0.0 1.8e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM18854.1 - 9.9e-07 28.7 0.1 2.2e-06 27.6 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM18854.1 - 1.8e-06 28.2 0.0 3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain LRR_8 PF13855.6 GAM18855.1 - 5.3e-13 48.5 7.5 0.00026 20.7 0.3 4.4 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 GAM18855.1 - 8.4e-10 38.8 17.0 0.00076 19.8 2.9 6.4 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAM18855.1 - 8.7e-07 28.6 0.9 1.1e-05 25.0 0.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeat Myosin_TH1 PF06017.13 GAM18855.1 - 4.4e-05 23.2 1.5 0.13 11.9 0.1 2.5 1 1 1 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding DUF1451 PF07295.11 GAM18855.1 - 0.007 16.4 3.7 1.7 8.7 2.8 2.6 2 0 0 2 2 2 2 Zinc-ribbon containing domain LRR_1 PF00560.33 GAM18855.1 - 0.012 16.0 3.2 82 4.4 0.0 5.9 4 1 0 4 4 4 0 Leucine Rich Repeat Ago_N_1 PF18351.1 GAM18855.1 - 0.11 12.9 0.6 2.8 8.4 0.1 3.1 2 0 0 2 2 2 0 Fungal Argonaute N-terminal domain LRR_6 PF13516.6 GAM18855.1 - 0.17 12.0 10.3 2.4 8.5 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich repeat EF-hand_8 PF13833.6 GAM18856.1 - 2e-10 40.4 0.3 5e-08 32.7 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 GAM18856.1 - 6e-10 39.4 0.0 7.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAM18856.1 - 1.2e-09 37.0 0.1 0.00054 19.3 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAM18856.1 - 1.9e-06 27.3 0.0 0.0035 17.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAM18856.1 - 0.0024 17.3 0.0 0.019 14.4 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 GAM18856.1 - 0.17 11.8 0.1 8.5 6.4 0.0 2.2 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF1573 PF07610.11 GAM18857.1 - 7.2e-08 32.4 15.1 0.33 11.0 0.0 10.3 13 0 0 13 13 13 3 Protein of unknown function (DUF1573) ASH PF15780.5 GAM18857.1 - 3.5e-06 27.1 16.8 0.43 10.8 0.0 10.4 10 3 3 13 13 13 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 GAM18857.1 - 0.00045 20.0 20.6 1.8 8.4 0.1 8.3 8 1 0 8 8 8 3 MSP (Major sperm protein) domain LEA_2 PF03168.13 GAM18857.1 - 0.0018 18.7 0.1 0.35 11.4 0.1 4.4 4 0 0 4 4 4 1 Late embryogenesis abundant protein PapD-like PF14874.6 GAM18857.1 - 0.02 15.0 0.6 70 3.7 0.0 5.1 5 0 0 5 5 5 0 Flagellar-associated PapD-like NOA36 PF06524.12 GAM18858.1 - 2.6 7.3 7.7 2.6 7.3 7.7 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GAM18858.1 - 4.7 5.4 7.3 5 5.3 7.3 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GAM18858.1 - 4.8 5.6 8.9 5.2 5.5 8.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1084 PF06454.11 GAM18860.1 - 1.4e-06 27.9 28.6 3.2e-06 26.7 28.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Clat_adaptor_s PF01217.20 GAM18861.1 - 6.7e-09 35.8 1.7 8.2e-09 35.5 1.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GST_C_3 PF14497.6 GAM18861.1 - 0.063 13.5 0.2 1.4 9.1 0.0 2.3 1 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain CBM49 PF09478.10 GAM18862.1 - 9.2e-14 51.5 0.1 2.3e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 Melibiase_2 PF16499.5 GAM18863.1 - 2.1e-77 260.1 4.3 3.5e-77 259.4 4.3 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 GAM18863.1 - 3.1e-23 81.6 1.0 1.1e-22 79.9 0.2 2.2 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 GAM18863.1 - 3.2e-06 26.3 0.0 6.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 GAM18863.1 - 8.6e-06 25.9 0.0 1.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Glyco_hydro_97 PF10566.9 GAM18863.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 TrbC PF04956.13 GAM18863.1 - 0.047 13.9 0.2 0.1 12.8 0.2 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family Glyco_hydro_30C PF17189.4 GAM18863.1 - 0.099 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain MobB PF03205.14 GAM18864.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.6 GAM18864.1 - 0.24 11.9 0.0 0.46 11.0 0.0 1.4 2 0 0 2 2 2 0 AAA domain RTP1_C1 PF10363.9 GAM18866.1 - 1.5e-12 47.7 0.9 1.8e-05 24.8 0.0 4.7 4 2 2 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 GAM18866.1 - 6.8e-06 25.7 0.0 1.7e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 DUF3385 PF11865.8 GAM18866.1 - 0.00044 20.2 4.9 0.0081 16.1 0.1 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) BPL_LplA_LipB PF03099.19 GAM18867.1 - 3.8e-10 39.8 0.0 6.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ALIX_LYPXL_bnd PF13949.6 GAM18867.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV LIAS_N PF16881.5 GAM18868.1 - 9e-26 90.4 0.6 2.2e-25 89.2 0.6 1.7 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 GAM18868.1 - 9e-11 42.4 0.8 1.7e-10 41.6 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Menin PF05053.13 GAM18868.1 - 0.2 10.0 2.1 0.3 9.4 2.1 1.2 1 0 0 1 1 1 0 Menin 7tm_3 PF00003.22 GAM18869.1 - 4.7e-28 98.5 36.2 4.7e-28 98.5 36.2 2.1 2 1 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Beta_helix PF13229.6 GAM18869.1 - 0.0032 17.3 1.7 0.0032 17.3 1.7 4.5 3 1 1 4 4 4 2 Right handed beta helix region TMEM100 PF16311.5 GAM18869.1 - 0.012 15.1 2.1 0.042 13.5 2.1 1.9 1 0 0 1 1 1 0 Transmembrane protein 100 CH PF00307.31 GAM18870.1 - 7e-38 129.2 10.6 1.6e-12 47.5 0.1 5.6 5 0 0 5 5 5 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM18870.1 - 0.00056 19.7 1.5 0.15 11.9 0.0 3.2 2 0 0 2 2 2 2 CAMSAP CH domain ATG16 PF08614.11 GAM18870.1 - 0.00087 19.6 20.9 0.00087 19.6 20.9 9.3 3 2 3 8 8 8 3 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 GAM18870.1 - 0.0016 18.8 5.6 0.0016 18.8 5.6 8.6 2 2 6 9 9 9 2 Bacterial type III secretion protein (HrpB7) GP3_package PF16677.5 GAM18870.1 - 2.1 8.5 7.9 1.5 9.0 0.4 3.8 3 0 0 3 3 3 0 DNA-packaging protein gp3 zf-C3HC4_3 PF13920.6 GAM18871.1 - 1.9e-08 34.0 5.4 3.1e-08 33.3 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM18871.1 - 7e-08 32.2 8.0 1.7e-07 31.0 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM18871.1 - 1.5e-06 28.0 8.3 3e-06 27.0 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM18871.1 - 7e-06 26.3 7.9 1.4e-05 25.3 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAM18871.1 - 3.2e-05 23.8 7.7 6.8e-05 22.8 7.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAM18871.1 - 0.00056 19.7 7.9 0.0028 17.5 8.0 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GAM18871.1 - 0.001 19.1 2.1 0.003 17.7 2.1 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 GAM18871.1 - 0.002 18.1 10.1 0.006 16.6 10.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Aconitase_C PF00694.19 GAM18871.1 - 0.065 13.6 7.5 0.17 12.2 1.7 2.8 2 0 0 2 2 2 0 Aconitase C-terminal domain zf-rbx1 PF12678.7 GAM18871.1 - 0.5 10.7 6.7 1.7 9.0 6.7 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 GAM18871.1 - 0.65 10.2 11.6 3.1 8.0 10.6 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAM18871.1 - 3.3 7.7 5.9 8 6.4 5.5 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 GAM18871.1 - 4.8 7.1 6.9 26 4.7 1.7 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain NAAA-beta PF15508.6 GAM18872.1 - 2.4e-07 31.0 0.0 4.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CBAH PF02275.18 GAM18872.1 - 1.6e-06 28.0 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family Beta_helix PF13229.6 GAM18873.1 - 0.00083 19.2 17.8 0.0066 16.3 17.8 2.1 1 1 0 1 1 1 1 Right handed beta helix region DUF5123 PF17161.4 GAM18873.1 - 1.3 10.1 13.7 47 5.1 13.7 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5123) Beta_helix PF13229.6 GAM18874.1 - 1.4e-05 25.0 16.6 1.4e-05 25.0 16.6 3.1 1 1 2 3 3 3 3 Right handed beta helix region CDtoxinA PF03498.14 GAM18875.1 - 0.0026 17.3 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 Cytolethal distending toxin A/C domain zf-Sec23_Sec24 PF04810.15 GAM18875.1 - 0.054 13.6 3.4 0.17 12.0 2.9 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF5558 PF17713.1 GAM18878.1 - 0.028 14.8 0.6 0.047 14.1 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5558) Peptidase_C48 PF02902.19 GAM18879.1 - 3.7e-08 33.5 0.0 4.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AAA_16 PF13191.6 GAM18881.1 - 0.03 14.7 0.0 0.083 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain LRR_RI_capping PF18779.1 GAM18881.1 - 0.037 13.7 0.0 0.12 12.0 0.0 1.9 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat AAA_22 PF13401.6 GAM18882.1 - 0.039 14.2 0.0 0.25 11.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain DUF1542 PF07564.11 GAM18882.1 - 0.16 12.1 0.1 0.4 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) HTH_Tnp_Tc5 PF03221.16 GAM18884.1 - 2.2e-05 24.4 0.2 6.5e-05 22.9 0.1 1.8 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain Transglut_core2 PF13369.6 GAM18884.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily E1_DerP2_DerF2 PF02221.15 GAM18885.1 - 8.7e-19 68.3 0.0 1e-18 68.1 0.0 1.0 1 0 0 1 1 1 1 ML domain FHA PF00498.26 GAM18886.1 - 4.3e-17 62.2 0.1 9.7e-17 61.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAM18886.1 - 2.3e-06 27.8 0.0 4.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SpoIIIAH PF12685.7 GAM18886.1 - 0.00081 19.3 3.9 0.0011 18.8 3.9 1.4 1 0 0 1 1 1 1 SpoIIIAH-like protein LBP_BPI_CETP PF01273.25 GAM18886.1 - 0.054 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain UPF0524 PF15823.5 GAM18886.1 - 0.094 12.1 1.6 0.15 11.4 1.6 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 LMBR1 PF04791.16 GAM18886.1 - 0.59 9.0 5.0 0.77 8.6 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CRT10 PF08728.10 GAM18886.1 - 1.5 6.9 5.3 2 6.5 5.3 1.1 1 0 0 1 1 1 0 CRT10 Presenilin PF01080.17 GAM18886.1 - 1.7 7.3 3.8 2.2 7.0 3.8 1.1 1 0 0 1 1 1 0 Presenilin MPM1 PF17234.2 GAM18886.1 - 3.9 7.7 10.4 0.51 10.6 5.8 1.8 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF3677 PF12432.8 GAM18887.1 - 2.9e-05 24.3 0.1 9e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3677) DUF3860 PF12976.7 GAM18887.1 - 5 7.2 5.5 1.9 8.6 0.4 2.9 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3860) Pribosyltran_N PF13793.6 GAM18888.1 - 3.3e-48 162.5 1.0 6.1e-47 158.4 0.1 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAM18888.1 - 4.9e-42 144.0 7.2 1.4e-38 132.8 1.7 3.5 3 1 1 4 4 4 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAM18888.1 - 1.1e-15 57.5 1.9 1.1e-15 57.5 1.9 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAM18888.1 - 0.0058 16.1 0.2 0.011 15.2 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CAF1 PF04857.20 GAM18889.1 - 5.7e-22 78.3 2.7 5.1e-11 42.3 0.0 2.7 2 1 0 3 3 3 2 CAF1 family ribonuclease Menin PF05053.13 GAM18889.1 - 1.7 6.9 4.4 2.4 6.4 4.4 1.2 1 0 0 1 1 1 0 Menin PLDc_2 PF13091.6 GAM18891.1 - 4.1e-23 81.7 0.1 9.9e-17 61.1 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAM18891.1 - 5.4e-08 32.7 2.5 0.00086 19.4 0.1 3.4 3 0 0 3 3 3 2 Phospholipase D Active site motif COX6B PF02297.17 GAM18892.1 - 2.6e-18 66.0 2.5 3.1e-18 65.8 2.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 GAM18892.1 - 0.0015 18.6 1.0 0.0025 17.9 1.0 1.5 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 GAM18892.1 - 0.14 12.2 1.5 0.21 11.6 1.5 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Guanylate_cyc_2 PF09778.9 GAM18893.1 - 1.1e-49 168.6 0.8 6.3e-49 166.2 0.8 1.8 1 1 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.6 GAM18893.1 - 1.4e-07 32.1 0.3 4.8e-05 24.0 0.0 2.6 2 1 0 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.15 GAM18893.1 - 1.2e-06 28.3 0.5 0.005 16.6 0.0 2.7 3 0 0 3 3 3 2 Peptidase C39 family Peptidase_C70 PF12385.8 GAM18893.1 - 1.7e-05 24.8 0.7 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 Papain-like cysteine protease AvrRpt2 BtrH_N PF14399.6 GAM18893.1 - 0.00024 21.3 0.4 0.032 14.5 0.1 2.3 2 0 0 2 2 2 2 Butirosin biosynthesis protein H, N-terminal HECT PF00632.25 GAM18894.1 - 1.4e-78 264.5 0.0 1.9e-78 264.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Kelch_6 PF13964.6 GAM18894.1 - 2.6e-23 81.4 7.4 1.3e-07 31.6 0.2 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 GAM18894.1 - 4.6e-22 77.8 9.4 1.7e-06 27.9 0.7 5.1 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM18894.1 - 2.7e-21 75.1 6.8 2.3e-06 27.5 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 GAM18894.1 - 1.8e-19 69.0 4.0 6.2e-08 32.1 0.1 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 GAM18894.1 - 6.9e-15 54.4 9.7 6.3e-06 26.0 0.2 4.8 4 1 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAM18894.1 - 1.5e-12 47.5 18.8 0.0037 17.5 0.2 6.1 4 2 0 4 4 4 4 Galactose oxidase, central domain Arch_fla_DE PF04659.13 GAM18894.1 - 0.069 13.0 0.6 2 8.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal flagella protein cwf18 PF08315.12 GAM18895.1 - 1.4e-20 74.3 10.6 1.4e-20 74.3 10.6 3.3 2 1 0 3 3 3 1 cwf18 pre-mRNA splicing factor ORC_WH_C PF18137.1 GAM18895.1 - 0.064 13.3 0.5 0.064 13.3 0.5 3.2 2 1 0 2 2 2 0 Origin recognition complex winged helix C-terminal BSP_II PF05432.11 GAM18895.1 - 4.8 6.8 43.4 0.092 12.4 7.1 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) LRR_6 PF13516.6 GAM18896.1 - 3.7e-36 120.1 54.8 1e-06 28.3 0.3 15.5 15 0 0 15 15 15 11 Leucine Rich repeat LRR_4 PF12799.7 GAM18896.1 - 5.4e-12 45.7 44.3 0.0061 17.0 1.2 9.9 7 2 6 13 13 13 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM18896.1 - 3.7e-11 42.0 14.9 6.3 7.8 0.4 11.4 11 2 0 11 11 11 3 Leucine Rich Repeat F-box-like PF12937.7 GAM18896.1 - 0.00031 20.6 2.7 0.0005 19.9 0.5 2.5 3 0 0 3 3 3 1 F-box-like Annexin PF00191.20 GAM18896.1 - 0.018 15.1 0.1 0.044 13.9 0.1 1.6 1 0 0 1 1 1 0 Annexin LRR_8 PF13855.6 GAM18896.1 - 0.055 13.2 52.4 0.089 12.6 3.7 11.2 8 3 3 11 11 10 0 Leucine rich repeat Pkinase PF00069.25 GAM18897.1 - 9.9e-80 267.7 0.0 1.3e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18897.1 - 5.6e-42 143.8 0.0 7.6e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM18897.1 - 0.00018 21.0 0.0 0.00036 20.0 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM18897.1 - 0.0048 16.3 0.0 0.027 13.8 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 GAM18897.1 - 0.12 12.3 0.0 0.75 9.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ten1_2 PF15490.6 GAM18898.1 - 3.5e-12 46.1 0.2 1.9e-10 40.5 0.0 2.4 2 1 0 2 2 2 1 Telomere-capping, CST complex subunit Tir_receptor_C PF07489.11 GAM18898.1 - 0.57 10.1 3.3 0.31 11.0 1.6 1.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Peptidase_M18 PF02127.15 GAM18899.1 - 1.6e-159 531.4 0.0 1.8e-159 531.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 GAM18899.1 - 1.3e-07 31.0 0.1 1.9e-06 27.1 0.0 2.4 2 1 1 3 3 3 2 M42 glutamyl aminopeptidase HSP90 PF00183.18 GAM18900.1 - 1.2e-93 314.8 1.9 1.7e-89 301.1 0.4 2.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 GAM18900.1 - 6.8e-10 38.9 0.1 1.9e-09 37.4 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAM18900.1 - 5.1e-09 36.6 0.1 9.9e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sacchrp_dh_C PF16653.5 GAM18902.1 - 5.3e-81 272.6 0.0 9.4e-81 271.8 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 GAM18902.1 - 9.2e-23 80.9 0.0 2.5e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GAM18902.1 - 0.00036 20.5 0.0 0.0012 18.8 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 GAM18902.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FNIP PF05725.12 GAM18903.1 - 5.8e-48 160.8 14.3 4.2e-11 42.8 0.1 6.7 5 1 0 6 6 6 6 FNIP Repeat Peptidase_S8 PF00082.22 GAM18904.1 - 9.6e-43 146.5 0.1 1.4e-42 146.0 0.1 1.2 1 0 0 1 1 1 1 Subtilase family ABC_transp_aux PF09822.9 GAM18904.1 - 0.0097 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system Ac76 PF05814.11 GAM18904.1 - 0.072 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) Usg PF06233.12 GAM18905.1 - 0.02 15.0 0.0 0.062 13.4 0.0 1.8 1 0 0 1 1 1 0 Usg-like family DUF3437 PF11919.8 GAM18905.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) RGS PF00615.19 GAM18906.1 - 1.2e-23 83.7 2.7 1.2e-23 83.7 2.7 2.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain LRR_8 PF13855.6 GAM18906.1 - 6e-20 70.8 19.9 2.4e-09 36.8 3.7 3.1 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 GAM18906.1 - 2.5e-13 49.9 14.3 1.7e-06 28.2 0.3 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAM18906.1 - 0.0006 19.7 4.5 0.39 10.9 0.1 4.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 GAM18906.1 - 0.004 17.5 9.4 15 6.6 0.0 6.0 5 1 0 5 5 5 2 Leucine Rich Repeat TraB PF01963.17 GAM18907.1 - 5.9e-16 59.2 10.4 3.4e-15 56.6 0.0 3.1 3 1 1 4 4 4 2 TraB family DUF702 PF05142.12 GAM18907.1 - 0.33 11.4 14.6 0.064 13.7 5.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Glyco_transf_10 PF00852.19 GAM18908.1 - 1.1e-35 122.9 0.6 2.5e-35 121.8 0.6 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 GAM18908.1 - 0.0084 16.6 0.2 0.029 14.8 0.0 2.0 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Pkinase_Tyr PF07714.17 GAM18909.1 - 5.4e-54 183.2 0.0 8.9e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM18909.1 - 2e-48 165.1 0.0 3.5e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 GAM18909.1 - 5.2e-25 87.9 4.6 1.7e-10 41.3 0.9 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM18909.1 - 2e-24 85.6 4.7 2.1e-05 25.0 0.0 6.3 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM18909.1 - 5.1e-22 77.6 3.7 8.2e-07 29.2 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM18909.1 - 8.4e-19 67.1 3.3 0.0093 16.4 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 GAM18909.1 - 1.4e-17 61.9 1.8 0.0017 18.7 0.1 6.1 5 0 0 5 5 5 3 Ankyrin repeat SAM_1 PF00536.30 GAM18909.1 - 2.4e-14 53.5 0.3 8e-14 51.8 0.3 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM18909.1 - 6.1e-10 39.1 0.2 1.8e-09 37.6 0.2 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Haspin_kinase PF12330.8 GAM18909.1 - 0.00017 20.7 0.1 0.015 14.2 0.0 2.5 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 GAM18909.1 - 0.015 14.9 0.5 0.11 12.0 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAM18909.1 - 0.033 14.1 0.3 0.13 12.2 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Slx4 PF09494.10 GAM18909.1 - 0.087 12.8 0.0 5.4 7.0 0.0 2.9 2 0 0 2 2 2 0 Slx4 endonuclease DUF2608 PF11019.8 GAM18910.1 - 0.016 14.7 3.5 0.27 10.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) MSC PF09402.10 GAM18911.1 - 1.9e-17 63.7 0.4 1.9e-17 63.7 0.4 2.6 2 1 0 2 2 2 1 Man1-Src1p-C-terminal domain TFIIA PF03153.13 GAM18911.1 - 0.0043 17.1 8.7 0.0043 17.1 8.7 2.3 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF2956 PF11169.8 GAM18911.1 - 0.0076 16.4 0.5 0.0076 16.4 0.5 4.8 4 1 1 5 5 5 1 Protein of unknown function (DUF2956) Rpr2 PF04032.16 GAM18912.1 - 2.7e-21 75.6 3.8 2.7e-21 75.6 3.8 2.5 3 0 0 3 3 3 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cytidylate_kin2 PF13189.6 GAM18912.1 - 0.022 14.9 1.4 0.026 14.7 0.8 1.4 1 1 0 1 1 1 0 Cytidylate kinase-like family FUR PF01475.19 GAM18912.1 - 0.15 12.2 5.2 0.16 12.1 1.4 2.4 1 1 2 3 3 3 0 Ferric uptake regulator family DUF3450 PF11932.8 GAM18912.1 - 5.5 6.2 13.8 0.43 9.8 6.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CSG2 PF16965.5 GAM18912.1 - 7.6 5.4 10.2 0.65 8.9 4.9 1.7 1 1 1 2 2 2 0 Ceramide synthase regulator Tenui_NS4 PF03300.13 GAM18913.1 - 0.079 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus non-structural, movement protein NS4 Kelch_6 PF13964.6 GAM18914.1 - 1.3e-14 53.8 7.5 8e-06 26.0 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM18914.1 - 1.7e-11 44.0 1.0 0.0048 16.9 0.2 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM18914.1 - 1.9e-06 28.0 0.2 0.036 14.4 0.0 4.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM18914.1 - 5.2e-06 25.9 1.3 0.34 10.5 0.1 5.2 4 1 0 4 4 4 1 Kelch motif zf-B_box PF00643.24 GAM18914.1 - 1.4e-05 25.2 3.9 3.8e-05 23.7 3.9 1.7 1 0 0 1 1 1 1 B-box zinc finger Kelch_2 PF07646.15 GAM18914.1 - 0.00026 20.8 2.7 5.8 7.1 0.0 4.8 4 0 0 4 4 4 1 Kelch motif Basic PF01586.16 GAM18914.1 - 0.22 12.7 0.9 0.74 11.0 0.9 1.9 1 0 0 1 1 1 0 Myogenic Basic domain Kelch_5 PF13854.6 GAM18914.1 - 0.62 10.1 0.0 0.62 10.1 0.0 4.8 5 0 0 5 5 5 0 Kelch motif FA_desaturase PF00487.24 GAM18915.1 - 1.1e-07 31.9 7.5 4.4e-06 26.7 7.5 2.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF2207 PF09972.9 GAM18915.1 - 0.052 12.3 3.8 1.3 7.7 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) YibE_F PF07907.11 GAM18915.1 - 0.066 12.7 4.9 0.22 11.0 0.8 2.1 1 1 1 2 2 2 0 YibE/F-like protein adh_short PF00106.25 GAM18916.1 - 9.7e-50 168.7 0.0 1.2e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM18916.1 - 6.5e-32 111.0 0.0 8.3e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM18916.1 - 4.1e-18 65.9 0.0 5.9e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM18916.1 - 6.7e-07 29.0 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM18916.1 - 1.3e-05 24.5 0.1 1.8e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 GAM18916.1 - 3.2e-05 24.2 0.1 4.9e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 GAM18916.1 - 6e-05 23.0 0.0 9.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 GAM18916.1 - 0.0001 21.6 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 GAM18916.1 - 0.00038 20.5 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 GAM18916.1 - 0.0008 18.9 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAM18916.1 - 0.0034 16.4 0.2 0.0055 15.7 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.6 GAM18916.1 - 0.033 14.6 0.1 0.069 13.6 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Zeta_toxin PF06414.12 GAM18916.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Y_phosphatase PF00102.27 GAM18917.1 - 2.9e-79 266.0 2.1 4e-79 265.5 2.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 GAM18917.1 - 1.6e-05 24.7 0.0 3.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 GAM18917.1 - 0.0011 19.0 0.1 0.0032 17.5 0.1 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 GAM18917.1 - 0.0021 18.2 0.3 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate FAM195 PF14799.6 GAM18917.1 - 0.079 13.3 1.4 0.18 12.2 0.3 2.2 2 0 0 2 2 2 0 FAM195 family Macoilin PF09726.9 GAM18917.1 - 5.4 5.4 15.6 7.2 5.0 15.6 1.1 1 0 0 1 1 1 0 Macoilin family UPF0137 PF03677.13 GAM18918.1 - 0.0037 17.1 0.4 0.0064 16.3 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0137) OST3_OST6 PF04756.13 GAM18920.1 - 5.4e-49 167.1 6.0 5.4e-49 167.1 6.0 1.3 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family DUF4064 PF13273.6 GAM18920.1 - 0.0029 17.9 0.9 0.0029 17.9 0.9 3.1 3 1 1 4 4 4 1 Protein of unknown function (DUF4064) AtpR PF12966.7 GAM18920.1 - 0.57 10.7 7.5 0.68 10.4 2.7 2.4 2 0 0 2 2 2 0 N-ATPase, AtpR subunit Imp-YgjV PF10688.9 GAM18920.1 - 1.4 8.7 9.4 0.085 12.7 0.8 2.7 3 0 0 3 3 3 0 Bacterial inner membrane protein DUF4131 PF13567.6 GAM18920.1 - 2.9 7.5 7.7 3.5 7.2 1.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) AcetylCoA_hydro PF02550.15 GAM18921.1 - 1e-39 136.6 0.0 1.8e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 GAM18921.1 - 1.4e-37 129.0 0.0 2.3e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DHR-2 PF06920.13 GAM18922.1 - 3e-170 567.4 8.3 5.1e-170 566.6 8.3 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 GAM18922.1 - 8.6e-38 130.1 0.5 2.4e-37 128.6 0.5 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 GAM18922.1 - 2.8e-06 27.7 0.8 2.8e-06 27.7 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) RPAP1_N PF08621.10 GAM18922.1 - 0.029 14.2 0.2 0.1 12.4 0.2 2.1 1 0 0 1 1 1 0 RPAP1-like, N-terminal Xpo1 PF08389.12 GAM18922.1 - 4 7.5 8.6 1.8 8.6 0.0 3.7 4 0 0 4 4 4 0 Exportin 1-like protein eIF3_p135 PF12807.7 GAM18924.1 - 0.019 15.0 0.4 0.024 14.7 0.4 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 SPT2 PF08243.11 GAM18924.1 - 0.019 15.5 0.5 0.034 14.7 0.5 1.4 1 0 0 1 1 1 0 SPT2 chromatin protein Enkurin PF13864.6 GAM18924.1 - 0.045 14.2 1.1 0.071 13.6 1.1 1.3 1 0 0 1 1 1 0 Calmodulin-binding OmpA PF00691.20 GAM18924.1 - 0.09 13.2 1.3 0.16 12.3 1.1 1.5 1 1 0 1 1 1 0 OmpA family Orf78 PF06024.12 GAM18924.1 - 0.16 12.3 0.7 0.63 10.4 0.0 2.1 1 1 1 2 2 2 0 Orf78 (ac78) DAO PF01266.24 GAM18925.1 - 9.4e-61 206.3 0.0 1.1e-60 206.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM18925.1 - 0.00065 18.8 0.3 0.023 13.7 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Mqo PF06039.15 GAM18925.1 - 0.00098 17.8 0.1 0.16 10.5 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 GAM18925.1 - 0.0016 17.8 0.1 0.0027 17.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAM18925.1 - 0.012 14.9 0.1 0.073 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM18925.1 - 0.032 14.2 0.1 0.48 10.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAM18925.1 - 0.065 12.5 0.1 1.3 8.2 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 GAM18925.1 - 0.065 13.5 0.2 0.16 12.2 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM18925.1 - 0.14 12.8 0.1 0.48 11.0 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_U4 PF03419.13 GAM18926.1 - 0.11 11.7 0.3 0.15 11.4 0.3 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA CCER1 PF15482.6 GAM18926.1 - 8.8 6.2 13.2 12 5.7 13.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 RasGEF_N PF00618.20 GAM18927.1 - 0.14 12.4 6.8 0.063 13.5 1.9 2.8 2 1 0 2 2 2 0 RasGEF N-terminal motif RasGEF PF00617.19 GAM18928.1 - 4.8e-47 160.4 2.5 4.8e-47 160.4 2.5 1.9 2 0 0 2 2 2 1 RasGEF domain DUF416 PF04222.12 GAM18928.1 - 2 7.8 7.9 1.9 7.9 0.1 3.7 3 1 0 4 4 4 0 Protein of unknown function (DUF416) Pkinase PF00069.25 GAM18929.1 - 9.9e-59 198.8 0.0 1.4e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18929.1 - 6.3e-44 150.2 0.0 9.3e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 GAM18929.1 - 0.0067 16.1 0.0 1 8.9 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 GAM18929.1 - 0.013 15.5 0.3 0.71 9.7 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family P3A PF08727.11 GAM18929.1 - 0.073 12.5 0.1 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Poliovirus 3A protein like Syja_N PF02383.18 GAM18930.1 - 5.1e-85 285.6 0.0 8.4e-85 284.9 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain QWRF PF04484.12 GAM18930.1 - 0.14 11.9 2.7 0.33 10.6 1.2 2.1 2 0 0 2 2 2 0 QWRF family FNIP PF05725.12 GAM18931.1 - 1.1e-85 281.6 27.1 1.6e-13 50.6 0.1 11.3 8 1 5 13 13 13 12 FNIP Repeat Pkinase PF00069.25 GAM18932.1 - 7.9e-63 212.3 0.0 1.2e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18932.1 - 1.2e-43 149.3 0.0 1.8e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TIG PF01833.24 GAM18932.1 - 7.1e-17 61.3 19.9 4.9e-07 29.7 0.7 5.2 4 0 0 4 4 4 4 IPT/TIG domain Pkinase_fungal PF17667.1 GAM18932.1 - 7.2e-06 25.0 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAM18932.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM18932.1 - 0.052 12.9 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Kinase-like EGF_2 PF07974.13 GAM18932.1 - 0.068 13.5 5.0 0.13 12.6 5.0 1.5 1 0 0 1 1 1 0 EGF-like domain FTA2 PF13095.6 GAM18932.1 - 0.17 11.5 0.4 10 5.6 0.2 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 I-EGF_1 PF18372.1 GAM18932.1 - 0.23 11.6 3.4 0.53 10.4 3.4 1.6 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 hEGF PF12661.7 GAM18932.1 - 4.4 8.1 5.9 12 6.7 5.9 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF zf-C3HC4 PF00097.25 GAM18933.1 - 0.0081 16.0 0.7 0.0081 16.0 0.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM18933.1 - 0.011 15.6 2.9 0.011 15.6 2.9 2.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM18933.1 - 0.022 15.1 0.7 0.022 15.1 0.7 2.7 2 1 1 3 3 3 0 Ring finger domain CEBP_ZZ PF16366.5 GAM18933.1 - 0.17 12.1 6.1 0.098 12.9 3.9 1.7 1 1 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-CSL PF05207.13 GAM18933.1 - 0.25 11.1 5.4 0.068 12.9 1.4 1.9 2 0 0 2 2 2 0 CSL zinc finger zf-RING_5 PF14634.6 GAM18933.1 - 0.92 9.5 11.3 4.7 7.3 11.3 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM18933.1 - 7.9 6.6 12.3 0.56 10.3 6.2 2.4 3 1 0 3 3 3 0 RING-type zinc-finger Beta_helix PF13229.6 GAM18934.1 - 0.00025 20.9 5.3 0.00025 20.9 5.3 2.2 1 1 1 2 2 2 1 Right handed beta helix region NosD PF05048.13 GAM18934.1 - 0.12 11.6 5.4 0.19 11.0 5.4 1.4 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DUF4404 PF14357.6 GAM18934.1 - 0.14 12.8 0.0 0.27 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) TIG PF01833.24 GAM18936.1 - 1.3e-58 195.0 119.9 6e-07 29.5 3.4 14.1 14 0 0 14 14 14 11 IPT/TIG domain EGF_2 PF07974.13 GAM18936.1 - 0.0011 19.3 5.8 0.0029 17.9 5.8 1.8 1 0 0 1 1 1 1 EGF-like domain I-EGF_1 PF18372.1 GAM18936.1 - 0.0077 16.3 3.7 0.022 14.8 3.7 1.8 1 0 0 1 1 1 1 Integrin beta epidermal growth factor like domain 1 PRIMA1 PF16101.5 GAM18936.1 - 0.12 12.4 3.8 0.85 9.7 0.7 2.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 hEGF PF12661.7 GAM18936.1 - 5.8 7.7 13.5 0.33 11.6 5.7 3.2 3 0 0 3 3 3 0 Human growth factor-like EGF MMTV_SAg PF01054.17 GAM18937.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen TIG PF01833.24 GAM18939.1 - 8.2e-23 80.3 67.0 1.9e-05 24.7 1.2 8.5 7 2 1 8 8 8 7 IPT/TIG domain YabP PF07873.11 GAM18939.1 - 0.0068 16.2 0.1 9.8 6.1 0.0 4.0 3 0 0 3 3 3 2 YabP family PRKCSH_1 PF13015.6 GAM18939.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein CBM_X2 PF03442.14 GAM18939.1 - 0.11 12.6 10.7 1.1 9.4 0.1 5.5 6 0 0 6 6 6 0 Carbohydrate binding domain X2 FLgD_tudor PF13861.6 GAM18939.1 - 9.3 6.6 8.6 3.2 8.1 0.2 3.7 3 0 0 3 3 3 0 FlgD Tudor-like domain Thymidylate_kin PF02223.17 GAM18940.1 - 2.6e-40 138.1 0.0 3e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 GAM18940.1 - 0.045 13.6 0.6 0.39 10.5 0.6 2.1 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_18 PF13238.6 GAM18940.1 - 0.094 13.3 0.1 0.29 11.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain ZZ PF00569.17 GAM18940.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, ZZ type AMP-binding PF00501.28 GAM18941.1 - 1.1e-91 307.6 0.0 1.8e-91 306.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Myotub-related PF06602.14 GAM18942.1 - 3.4e-132 440.7 0.0 7.6e-132 439.5 0.0 1.6 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ank_4 PF13637.6 GAM18942.1 - 9.2e-23 80.3 1.1 8.8e-08 32.6 0.1 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM18942.1 - 5.9e-22 78.1 3.0 1e-10 42.1 0.8 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM18942.1 - 5.8e-20 69.3 0.4 0.00091 19.5 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 GAM18942.1 - 1.1e-17 63.6 4.1 0.00031 21.1 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAM18942.1 - 3.4e-17 62.3 0.1 2.5e-07 30.8 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) GRAM PF02893.20 GAM18942.1 - 0.0077 16.1 0.8 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 GRAM domain DUF3447 PF11929.8 GAM18942.1 - 0.015 15.3 0.9 5.3 7.1 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Y_phosphatase3 PF13350.6 GAM18942.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family ECH_2 PF16113.5 GAM18943.1 - 4.9e-128 427.3 0.0 5.6e-128 427.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAM18943.1 - 6.9e-32 110.7 0.0 3.6e-30 105.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase INTS2 PF14750.6 GAM18943.1 - 0.012 13.3 0.0 0.015 12.9 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 PTR PF12789.7 GAM18943.1 - 0.083 13.0 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Phage tail repeat like Frizzled PF01534.17 GAM18944.1 - 1.8e-09 37.1 19.2 3e-09 36.4 19.2 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 GAM18944.1 - 5.2e-07 29.2 14.0 8.2e-07 28.5 14.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 GAM18944.1 - 2.2e-06 27.0 14.7 2.2e-06 27.0 14.7 1.5 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 GAM18944.1 - 0.36 10.1 17.8 0.028 13.8 10.8 2.0 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Ank_3 PF13606.6 GAM18945.1 - 0.071 13.7 2.4 1.3e+02 3.7 0.0 5.1 5 0 0 5 5 5 0 Ankyrin repeat TA0956 PF11513.8 GAM18945.1 - 0.077 13.2 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 SET PF00856.28 GAM18946.1 - 1.3e-12 48.4 0.4 8.8e-12 45.7 0.0 2.2 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 GAM18946.1 - 4.6e-07 30.6 6.0 1.5e-06 28.9 0.5 2.9 2 1 1 3 3 3 1 Rubisco LSMT substrate-binding MIOX PF05153.15 GAM18946.1 - 0.038 13.6 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 Myo-inositol oxygenase ApbA_C PF08546.11 GAM18946.1 - 0.13 12.5 0.0 0.37 11.0 0.0 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal STATa_Ig PF18214.1 GAM18948.1 - 1.3e-44 151.1 0.7 1.3e-44 151.1 0.7 3.5 3 0 0 3 3 3 1 STATa Immunoglobulin-like domain EF-hand_12 PF17901.1 GAM18948.1 - 1.9e-41 140.4 3.3 1.9e-41 140.4 3.3 2.4 3 0 0 3 3 3 1 EF-hand fold domain Dict-STAT-coil PF09267.10 GAM18948.1 - 5e-29 101.0 12.3 5e-29 101.0 12.3 3.3 3 0 0 3 3 3 1 Dictyostelium STAT, coiled coil SH2 PF00017.24 GAM18948.1 - 8.1e-05 22.7 0.0 0.00025 21.1 0.0 1.9 1 0 0 1 1 1 1 SH2 domain DUF3799 PF12684.7 GAM18948.1 - 0.17 11.7 1.7 0.37 10.5 1.7 1.5 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) zf-CCCH_2 PF14608.6 GAM18949.1 - 0.005 17.3 2.9 0.0088 16.5 2.9 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 GAM18949.1 - 0.23 11.3 3.9 0.39 10.6 3.9 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 GAM18949.1 - 0.39 10.7 4.9 0.78 9.7 4.9 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Miga PF10265.9 GAM18949.1 - 1.8 7.4 12.1 3 6.7 12.1 1.6 1 0 0 1 1 1 0 Mitoguardin Kelch_6 PF13964.6 GAM18950.1 - 4e-11 42.8 4.2 0.1 12.9 0.0 5.6 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM18950.1 - 1.2e-09 38.1 3.5 0.024 14.7 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM18950.1 - 2.9e-08 33.2 7.5 0.15 11.7 0.0 5.7 5 1 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 GAM18950.1 - 2.2e-06 27.5 13.7 0.31 11.1 0.9 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 GAM18950.1 - 0.00044 20.1 5.9 0.88 9.7 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Peptidase_M73 PF12389.8 GAM18950.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Fer4_24 PF18109.1 GAM18950.1 - 1.3 9.3 5.0 13 6.2 1.1 3.0 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain Fucokinase PF07959.12 GAM18951.1 - 9.8e-60 202.6 0.0 1.4e-59 202.1 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.26 GAM18951.1 - 1.2e-07 31.8 0.5 2.8e-07 30.7 0.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAM18951.1 - 7.8e-06 26.2 0.0 2.1e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Kelch_6 PF13964.6 GAM18952.1 - 1.4e-10 41.0 5.1 0.0014 18.8 0.0 4.8 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 GAM18952.1 - 1.7e-09 37.1 1.6 0.0032 17.0 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAM18952.1 - 1.4e-08 34.6 4.5 0.0004 20.3 0.1 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM18952.1 - 7.3e-05 22.9 3.7 0.21 11.9 0.0 5.1 4 1 1 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM18952.1 - 0.00017 21.4 4.8 1.4 9.0 0.2 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 GAM18952.1 - 0.01 15.8 10.9 0.16 12.0 0.3 4.7 5 0 0 5 5 5 0 Kelch motif LRR_9 PF14580.6 GAM18953.1 - 5.1e-14 52.2 3.8 1.3e-13 50.8 3.8 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 GAM18953.1 - 1.1e-13 51.1 13.0 1.9e-06 28.1 1.5 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM18953.1 - 4.3e-08 32.8 13.3 1.6e-05 24.6 0.6 3.6 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 GAM18953.1 - 0.028 14.5 18.8 0.33 11.1 1.1 4.7 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 GAM18953.1 - 0.74 10.6 9.6 12 6.9 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat Apc15p PF05841.11 GAM18953.1 - 1.3 9.9 9.4 17 6.3 9.4 2.3 1 1 0 1 1 1 0 Apc15p protein Tmemb_9 PF05434.11 GAM18954.1 - 0.18 11.7 0.0 0.18 11.7 0.0 2.3 1 1 1 2 2 2 0 TMEM9 DUF2663 PF10864.8 GAM18954.1 - 0.4 11.1 2.8 0.46 10.9 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) DUF1771 PF08590.10 GAM18956.1 - 3.2e-16 59.4 8.8 3.2e-16 59.4 8.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.16 GAM18956.1 - 2e-13 49.7 1.0 3.6e-05 23.4 0.0 3.5 3 0 0 3 3 3 2 CUE domain Smr PF01713.21 GAM18956.1 - 2e-06 28.0 0.1 5.5e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Smr domain DUF3439 PF11921.8 GAM18956.1 - 0.12 12.4 3.9 0.32 11.0 3.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LsmAD PF06741.13 GAM18957.1 - 1.7e-24 86.1 5.3 1.7e-24 86.1 5.3 2.7 4 0 0 4 4 4 1 LsmAD domain SM-ATX PF14438.6 GAM18957.1 - 3e-10 40.1 0.0 8.2e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.22 GAM18957.1 - 0.051 13.3 0.1 0.099 12.3 0.1 1.4 1 0 0 1 1 1 0 LSM domain PAM2 PF07145.15 GAM18957.1 - 0.059 13.1 6.9 2 8.3 0.8 3.2 1 1 1 2 2 2 0 Ataxin-2 C-terminal region EGF_2 PF07974.13 GAM18958.1 - 0.00038 20.7 11.2 0.00088 19.6 11.2 1.6 1 0 0 1 1 1 1 EGF-like domain Pur_ac_phosph_N PF16656.5 GAM18958.1 - 0.021 15.4 3.9 0.031 14.8 2.4 2.1 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain I-EGF_1 PF18372.1 GAM18958.1 - 0.14 12.2 8.3 0.27 11.3 8.3 1.4 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 MFS_1_like PF12832.7 GAM18959.1 - 1.8e-56 191.7 29.7 1.5e-29 103.1 13.2 2.6 1 1 1 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 GAM18959.1 - 1.8e-12 46.9 27.7 6.8e-08 31.8 5.8 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 GAM18959.1 - 5.3e-10 38.8 20.8 4.5e-07 29.2 7.2 2.0 1 1 1 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 GAM18959.1 - 1.1e-05 24.4 24.3 1.4e-05 24.0 11.5 2.2 1 1 1 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.13 GAM18959.1 - 0.63 8.4 8.3 0.13 10.6 0.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2052 PF09747.9 GAM18960.1 - 7.3e-16 58.9 38.8 7.3e-16 58.9 38.8 3.2 3 1 0 3 3 3 1 Coiled-coil domain containing protein (DUF2052) BUD22 PF09073.10 GAM18960.1 - 3.3 7.0 27.4 0.086 12.2 20.8 1.6 2 0 0 2 2 2 0 BUD22 Oxysterol_BP PF01237.18 GAM18962.1 - 0.15 10.9 0.1 0.25 10.1 0.1 1.3 1 0 0 1 1 1 0 Oxysterol-binding protein ATG27 PF09451.10 GAM18963.1 - 1.8e-12 47.7 0.4 3.7e-12 46.7 0.4 1.5 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 GAM18963.1 - 1.1e-11 44.4 0.0 1.3e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 GAM18963.1 - 2.1e-09 37.6 3.9 1.7e-06 28.1 0.4 2.3 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 GAM18963.1 - 2e-06 27.5 0.4 3.1e-06 27.0 0.4 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Trp_Tyr_perm PF03222.13 GAM18964.1 - 0.00035 19.7 0.7 0.00035 19.7 0.7 3.3 3 1 0 3 3 3 2 Tryptophan/tyrosine permease family Aa_trans PF01490.18 GAM18964.1 - 1.2 7.7 25.5 0.023 13.4 2.3 3.2 3 0 0 3 3 3 0 Transmembrane amino acid transporter protein FancD2 PF14631.6 GAM18965.1 - 5.4e-132 441.7 29.9 1.6e-112 377.1 18.5 6.0 3 2 2 6 6 6 3 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 GAM18965.1 - 0.0006 20.1 3.6 0.00086 19.6 0.1 3.3 3 0 0 3 3 3 1 FANCI solenoid 2 Annexin PF00191.20 GAM18966.1 - 5.2e-73 241.1 1.1 1.1e-20 73.4 0.2 4.1 4 0 0 4 4 4 4 Annexin DUF2312 PF10073.9 GAM18966.1 - 0.13 11.9 0.2 27 4.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Sporozoite_P67 PF05642.11 GAM18966.1 - 0.71 7.9 2.8 0.96 7.4 2.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HEAT PF02985.22 GAM18967.1 - 2.7e-15 55.1 2.3 0.0049 17.0 0.1 9.4 9 0 0 9 9 8 2 HEAT repeat HEAT_EZ PF13513.6 GAM18967.1 - 2.1e-14 53.6 0.0 0.012 16.2 0.0 7.7 6 1 1 7 7 7 3 HEAT-like repeat Importin_rep_4 PF18808.1 GAM18967.1 - 1.9e-08 34.5 0.8 1.9e-08 34.5 0.8 3.8 4 1 1 5 5 4 1 Importin repeat HEAT_2 PF13646.6 GAM18967.1 - 4.4e-08 33.4 0.0 1.2 9.5 0.0 5.3 5 1 0 5 5 4 2 HEAT repeats Vac14_Fab1_bd PF12755.7 GAM18967.1 - 2.1e-06 28.2 0.2 0.0016 19.0 0.0 5.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAM18967.1 - 1.8e-05 24.8 6.9 0.0001 22.4 0.0 4.7 4 3 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 GAM18967.1 - 0.00061 19.6 0.0 0.07 12.9 0.0 3.3 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis IBN_N PF03810.19 GAM18967.1 - 0.00088 19.1 0.5 0.05 13.5 0.4 3.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.8 GAM18967.1 - 0.0011 18.6 1.9 0.0093 15.6 0.0 3.4 3 2 1 4 4 4 1 CLASP N terminal B56 PF01603.20 GAM18967.1 - 0.0013 17.8 0.1 0.0013 17.8 0.1 2.9 3 0 0 3 3 3 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF577 PF04510.12 GAM18967.1 - 0.0015 18.5 4.9 0.0047 16.9 0.1 3.5 3 0 0 3 3 3 1 Family of unknown function (DUF577) DUF3385 PF11865.8 GAM18967.1 - 0.0052 16.7 2.8 5.9 6.8 0.0 5.0 4 2 0 4 4 4 1 Domain of unknown function (DUF3385) Cnd3 PF12719.7 GAM18967.1 - 0.052 12.7 7.6 0.24 10.6 0.1 4.8 4 1 1 5 5 5 0 Nuclear condensing complex subunits, C-term domain V-ATPase_H_C PF11698.8 GAM18967.1 - 0.074 13.2 0.0 14 5.9 0.0 3.7 3 0 0 3 3 3 0 V-ATPase subunit H Arm PF00514.23 GAM18967.1 - 0.093 12.8 0.0 8.8 6.5 0.0 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat U3snoRNP10 PF12397.8 GAM18967.1 - 0.9 9.9 4.1 78 3.7 0.2 5.1 6 0 0 6 6 5 0 U3 small nucleolar RNA-associated protein 10 polyprenyl_synt PF00348.17 GAM18968.1 - 1.5e-66 224.1 0.1 1.8e-66 223.8 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF5600 PF18150.1 GAM18969.1 - 1.9e-41 141.0 0.2 4.4e-41 139.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 GAM18969.1 - 1.2e-20 73.4 0.0 4.6e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.23 GAM18969.1 - 2.9e-13 50.2 0.0 6.5e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 GAM18969.1 - 8.1e-11 41.6 0.0 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 GAM18969.1 - 7.2e-08 32.5 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.32 GAM18969.1 - 9.2e-06 24.9 0.2 3.8e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 EF hand Roc PF08477.13 GAM18969.1 - 0.00071 19.8 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_8 PF13833.6 GAM18969.1 - 0.0036 17.1 0.1 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 GAM18969.1 - 0.0047 17.4 0.1 0.025 15.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM18969.1 - 0.012 15.4 0.1 0.075 13.0 0.1 2.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 GAM18969.1 - 0.068 12.7 0.1 0.23 11.1 0.1 1.9 1 0 0 1 1 1 0 EF hand AAA_28 PF13521.6 GAM18969.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1348 PF07080.11 GAM18970.1 - 1.7e-63 212.3 8.7 2e-63 212.1 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 GAM18970.1 - 1e-07 32.5 0.4 1.3e-07 32.2 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 GAM18970.1 - 0.00052 20.4 0.1 0.00066 20.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 GAM18970.1 - 0.005 16.6 0.2 0.007 16.2 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Y_phosphatase3 PF13350.6 GAM18971.1 - 1.5e-42 146.2 0.0 3.9e-28 99.0 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 GAM18971.1 - 1.1e-05 25.0 0.1 0.00013 21.6 0.0 2.4 2 1 0 2 2 2 1 Tyrosine phosphatase family SANTA PF09133.10 GAM18971.1 - 0.08 13.4 0.6 7.6 7.1 0.0 2.6 2 0 0 2 2 2 0 SANTA (SANT Associated) PAP1 PF08601.10 GAM18971.1 - 2.9 7.5 15.0 5.3 6.7 15.0 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Vps39_2 PF10367.9 GAM18972.1 - 4.1e-28 98.0 1.2 9.1e-28 96.9 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 GAM18972.1 - 8.2e-24 84.7 0.0 1.8e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 GAM18972.1 - 2.4e-07 30.7 15.8 2e-06 27.8 1.8 3.7 4 0 0 4 4 4 2 Region in Clathrin and VPS Vps39_1 PF10366.9 GAM18972.1 - 0.00052 20.3 0.2 0.00052 20.3 0.2 3.4 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 DUF2175 PF09943.9 GAM18972.1 - 0.077 13.3 0.5 0.31 11.3 0.5 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) TPR_2 PF07719.17 GAM18972.1 - 0.66 10.2 5.2 4.4 7.7 0.9 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM18972.1 - 2.5 8.0 6.3 1.4 8.9 0.6 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM18972.1 - 5.2 7.3 4.9 81 3.6 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.16 GAM18973.1 - 6.4e-13 48.3 31.4 6.4e-13 48.3 31.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2627 PF11118.8 GAM18973.1 - 2.9 8.5 5.7 17 6.0 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) TIG PF01833.24 GAM18976.1 - 1.3e-45 153.3 216.0 5.6e-06 26.4 3.8 20.3 13 5 8 21 21 21 15 IPT/TIG domain CzcE PF16986.5 GAM18976.1 - 0.1 12.9 0.2 0.57 10.5 0.1 2.4 2 0 0 2 2 2 0 Heavy-metal resistance protein CzcE EGF_2 PF07974.13 GAM18976.1 - 0.86 10.0 12.8 1.9 8.9 12.8 1.6 1 0 0 1 1 1 0 EGF-like domain HCBP_related PF06594.11 GAM18976.1 - 8.6 6.4 7.5 3.1 7.8 0.1 3.8 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain Surp PF01805.20 GAM18977.1 - 3.6e-14 52.5 0.1 8.5e-14 51.3 0.1 1.7 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 GAM18977.1 - 2e-13 50.0 0.0 5e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.8 GAM18977.1 - 2.2e-07 30.9 0.2 5.2e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 GAM18977.1 - 0.0082 16.9 0.1 0.034 15.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Ribosomal_L19e PF01280.20 GAM18978.1 - 2.5e-39 134.6 9.7 2.5e-38 131.4 0.5 2.9 1 1 2 3 3 3 2 Ribosomal protein L19e TM2 PF05154.16 GAM18979.1 - 4.9e-21 74.8 11.1 7.4e-21 74.2 11.1 1.2 1 0 0 1 1 1 1 TM2 domain FIBP PF05427.11 GAM18980.1 - 4.7e-65 220.2 0.5 1.2e-48 166.2 0.1 2.0 2 0 0 2 2 2 2 Acidic fibroblast growth factor binding (FIBP) SUIM_assoc PF16619.5 GAM18980.1 - 1.4 9.0 7.3 0.35 11.0 0.4 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 zf-RING_2 PF13639.6 GAM18981.1 - 3.8e-07 30.3 13.6 9e-07 29.1 13.6 1.7 1 0 0 1 1 1 1 Ring finger domain PWI PF01480.17 GAM18981.1 - 1.4e-06 28.5 0.0 3.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 PWI domain zf-C3HC4 PF00097.25 GAM18981.1 - 9.6e-06 25.4 12.0 9.6e-06 25.4 12.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM18981.1 - 3.3e-05 23.7 7.3 3.3e-05 23.7 7.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM18981.1 - 3.9e-05 23.4 13.8 8.2e-05 22.4 13.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM18981.1 - 0.0062 16.5 11.2 0.02 14.9 11.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAM18981.1 - 0.0076 16.5 12.1 0.031 14.6 12.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAM18981.1 - 0.021 14.9 4.3 0.055 13.5 4.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Act-Frag_cataly PF09192.10 GAM18981.1 - 0.028 13.8 0.2 0.051 13.0 0.2 1.4 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic DUF1644 PF07800.12 GAM18981.1 - 0.21 11.6 7.8 11 6.1 3.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_5 PF14634.6 GAM18981.1 - 0.28 11.2 10.9 1.3 9.0 11.2 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_15 PF17032.5 GAM18981.1 - 0.5 11.2 8.4 0.18 12.6 5.1 2.0 2 0 0 2 2 2 0 zinc-ribbon family Baculo_IE-1 PF05290.11 GAM18981.1 - 0.77 9.7 9.6 0.16 11.9 4.4 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 GAM18981.1 - 1.8 8.4 9.1 6.4 6.7 9.1 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Dicty_REP PF05086.12 GAM18982.1 - 0.0025 15.9 4.4 0.0038 15.3 4.4 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Pex14_N PF04695.13 GAM18982.1 - 0.0081 16.8 1.6 0.0081 16.8 1.6 2.2 1 1 1 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3254 PF11630.8 GAM18984.1 - 0.063 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) G-alpha PF00503.20 GAM18986.1 - 1.7e-116 389.2 6.0 2.1e-116 388.9 6.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM18986.1 - 1.4e-15 57.1 0.6 2.2e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM18986.1 - 0.00028 20.3 1.8 0.083 12.2 0.0 2.9 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM18986.1 - 0.0031 17.7 0.5 1.5 9.1 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 GAM18986.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain XRN_N PF03159.18 GAM18987.1 - 1.3e-72 244.2 0.1 2.1e-72 243.5 0.1 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 GAM18987.1 - 2e-64 218.2 1.0 1e-45 156.6 0.0 2.9 2 1 1 3 3 3 2 Xrn1 helical domain PITH PF06201.13 GAM18987.1 - 5.9e-18 65.5 3.7 5.9e-18 65.5 3.7 2.5 2 0 0 2 2 2 1 PITH domain RRM_1 PF00076.22 GAM18987.1 - 8.4e-18 64.0 0.0 6.2e-10 38.8 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA_4 PF14555.6 GAM18987.1 - 0.00013 21.7 0.0 0.00034 20.4 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain Nup35_RRM_2 PF14605.6 GAM18987.1 - 0.00063 19.7 0.0 0.0018 18.2 0.0 1.9 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCHC_3 PF13917.6 GAM18987.1 - 0.0059 16.5 1.0 0.013 15.5 0.4 1.8 2 0 0 2 2 2 1 Zinc knuckle UCH PF00443.29 GAM18987.1 - 0.016 14.7 0.5 0.85 9.1 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Smg4_UPF3 PF03467.15 GAM18987.1 - 0.032 14.3 0.1 0.08 13.0 0.1 1.7 1 0 0 1 1 1 0 Smg-4/UPF3 family HTH_40 PF14493.6 GAM18987.1 - 0.052 14.0 0.1 0.21 12.1 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain RRM_occluded PF16842.5 GAM18987.1 - 0.096 12.6 0.0 0.67 9.9 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif zf-CCHC PF00098.23 GAM18987.1 - 1.3 9.3 2.6 3.5 7.9 2.6 1.8 1 0 0 1 1 1 0 Zinc knuckle Kinesin PF00225.23 GAM18988.1 - 6e-102 341.0 2.7 6e-102 341.0 2.7 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAM18988.1 - 2.3e-26 92.5 4.6 3.4e-26 92.0 0.8 2.5 2 0 0 2 2 2 1 Microtubule binding Ribosomal_S26e PF01283.19 GAM18989.1 - 3.2e-47 159.4 8.1 3.8e-47 159.2 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 GAM18989.1 - 0.26 11.9 4.1 1.3 9.7 4.2 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Syntaxin-18_N PF10496.9 GAM18990.1 - 1.2e-11 44.7 1.9 1.2e-11 44.7 1.9 2.7 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 GAM18990.1 - 0.012 15.6 0.1 0.031 14.3 0.1 1.8 1 0 0 1 1 1 0 SNARE domain DUF3972 PF13118.6 GAM18990.1 - 1.8 9.0 8.6 0.17 12.3 2.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3972) APG9 PF04109.16 GAM18991.1 - 1.3e-171 571.8 20.7 1.6e-171 571.5 20.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Fib_succ_major PF09603.10 GAM18991.1 - 0.087 13.5 0.1 0.16 12.6 0.1 1.3 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) STAC2_u1 PF16664.5 GAM18991.1 - 0.11 13.0 1.3 0.26 11.8 1.3 1.5 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 SUIM_assoc PF16619.5 GAM18991.1 - 0.83 9.8 9.3 0.48 10.5 3.8 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 GAM18991.1 - 7.9 5.5 6.6 0.78 8.8 1.9 1.6 2 0 0 2 2 2 0 Drosophila roughex protein WD40 PF00400.32 GAM18992.1 - 3.7e-51 170.0 12.4 1.2e-08 35.5 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 GAM18992.1 - 6.6e-42 142.8 5.0 1.2e-41 142.0 5.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 GAM18992.1 - 2.4e-11 43.8 0.0 0.011 16.0 0.0 4.6 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM18992.1 - 1.5e-06 27.4 0.2 0.069 12.1 0.1 3.9 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAM18992.1 - 2.9e-06 26.2 7.2 0.5 8.9 2.5 4.5 3 1 1 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 GAM18992.1 - 6.2e-06 25.8 0.0 0.00076 18.9 0.0 3.6 4 0 0 4 4 4 1 WD40-like domain LisH PF08513.11 GAM18992.1 - 0.00082 19.3 0.1 0.0024 17.7 0.1 1.9 1 0 0 1 1 1 1 LisH Frtz PF11768.8 GAM18992.1 - 0.032 12.6 0.0 0.059 11.7 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 GAM18992.1 - 0.044 13.1 0.6 3.2 7.0 0.0 2.7 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal ELYS-bb PF16687.5 GAM18992.1 - 0.071 11.7 0.0 0.98 8.0 0.0 2.2 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin TTL PF03133.15 GAM18993.1 - 1.4e-65 221.4 7.3 1.4e-65 221.4 7.3 2.4 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GAM18993.1 - 1.3e-05 24.5 1.9 0.0025 17.1 0.0 2.7 2 1 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 GAM18993.1 - 0.00027 20.3 0.0 0.0024 17.2 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 GAM18993.1 - 0.0025 17.9 0.2 2.1 8.4 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain RimK PF08443.11 GAM18993.1 - 0.029 14.0 0.0 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain tRNA-synt_2 PF00152.20 GAM18994.1 - 2e-77 260.4 0.2 2.5e-77 260.0 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAM18994.1 - 4.3e-11 42.6 0.0 7.8e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAM18994.1 - 6.2e-09 35.7 0.0 3.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Pkinase PF00069.25 GAM18995.1 - 4.5e-70 236.0 0.6 4.5e-70 236.0 0.6 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM18995.1 - 1e-35 123.3 0.0 1e-35 123.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.18 GAM18995.1 - 1.1e-23 83.2 2.1 1.3e-13 50.9 0.1 2.9 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_fungal PF17667.1 GAM18995.1 - 6.8e-08 31.7 2.3 2.3e-07 29.9 0.1 2.3 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAM18995.1 - 9.5e-08 31.7 1.5 6.8e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Mannitol_dh PF01232.23 GAM18995.1 - 0.068 13.3 0.9 0.17 12.0 0.9 1.7 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain CNP1 PF08750.11 GAM18995.1 - 0.19 11.7 2.4 0.29 11.1 0.1 2.2 2 0 0 2 2 2 0 CNP1-like family Patatin PF01734.22 GAM18996.1 - 4.7e-09 36.7 0.1 4.7e-09 36.7 0.1 2.4 2 0 0 2 2 2 1 Patatin-like phospholipase Opi1 PF08618.10 GAM18996.1 - 0.00032 20.1 4.0 0.00048 19.5 4.0 1.1 1 0 0 1 1 1 1 Transcription factor Opi1 WW PF00397.26 GAM18996.1 - 0.012 15.7 0.4 0.03 14.4 0.4 1.7 1 0 0 1 1 1 0 WW domain Presenilin PF01080.17 GAM18996.1 - 1.5 7.5 8.4 0.27 10.0 4.5 1.6 2 0 0 2 2 2 0 Presenilin HABP4_PAI-RBP1 PF04774.15 GAM18997.1 - 0.0013 19.6 1.1 0.0016 19.3 1.1 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family BUD22 PF09073.10 GAM18998.1 - 4.3 6.6 99.8 0.089 12.1 67.0 3.0 1 1 1 2 2 2 0 BUD22 BRO1 PF03097.18 GAM18999.1 - 3.5e-25 88.6 0.2 4.5e-25 88.3 0.2 1.0 1 0 0 1 1 1 1 BRO1-like domain PseudoU_synth_2 PF00849.22 GAM19000.1 - 1.3e-20 74.1 0.0 1.8e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Pox_Ag35 PF03286.14 GAM19001.1 - 7.3 6.3 13.7 0.16 11.7 5.1 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DHHC PF01529.20 GAM19002.1 - 3.9e-39 133.8 11.1 3.9e-39 133.8 11.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase UPF0242 PF06785.11 GAM19002.1 - 4.2e-05 23.7 2.3 6.1e-05 23.2 2.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus SID-1_RNA_chan PF13965.6 GAM19002.1 - 0.0075 14.7 0.6 0.014 13.9 0.6 1.4 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF4834 PF16118.5 GAM19002.1 - 0.012 16.5 1.7 0.035 15.1 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 GAM19002.1 - 0.019 15.0 0.4 0.03 14.4 0.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 GAM19002.1 - 0.038 13.2 0.1 0.068 12.4 0.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter CLN3 PF02487.17 GAM19002.1 - 0.041 12.9 0.9 0.064 12.3 0.9 1.2 1 0 0 1 1 1 0 CLN3 protein Poty_coat PF00767.18 GAM19002.1 - 0.13 11.8 2.3 0.2 11.2 2.3 1.2 1 0 0 1 1 1 0 Potyvirus coat protein Connexin PF00029.19 GAM19002.1 - 0.18 11.6 6.4 0.031 14.0 1.8 1.9 2 0 0 2 2 2 0 Connexin Presenilin PF01080.17 GAM19002.1 - 0.27 10.0 6.1 0.51 9.1 6.1 1.4 1 0 0 1 1 1 0 Presenilin EPL1 PF10513.9 GAM19002.1 - 0.31 11.4 11.0 0.44 10.9 11.0 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Ctr PF04145.15 GAM19002.1 - 0.75 10.4 3.6 1.7 9.2 0.4 2.3 2 0 0 2 2 2 0 Ctr copper transporter family DUF1272 PF06906.11 GAM19002.1 - 0.97 9.6 6.5 2.9 8.1 6.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Peptidase_S49_N PF08496.10 GAM19002.1 - 3.6 7.6 10.0 0.15 12.1 4.3 1.6 2 0 0 2 2 1 0 Peptidase family S49 N-terminal FAM76 PF16046.5 GAM19002.1 - 5.4 6.3 20.8 0.059 12.7 7.5 2.1 2 0 0 2 2 2 0 FAM76 protein Glyco_transf_49 PF13896.6 GAM19003.1 - 2.8e-42 145.2 3.0 3.7e-32 112.0 0.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAM19003.1 - 0.00026 20.8 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Coiled PF05710.12 GAM19004.1 - 0.012 16.4 13.3 0.015 16.1 13.3 1.1 1 0 0 1 1 1 0 Coiled coil Ammonium_transp PF00909.21 GAM19005.1 - 4.8e-100 335.0 20.3 5.8e-100 334.8 20.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family GAD-like PF08887.11 GAM19005.1 - 0.0075 16.0 0.8 0.098 12.4 0.1 2.4 2 0 0 2 2 2 1 GAD-like domain zf-C2H2_6 PF13912.6 GAM19006.1 - 0.015 15.2 1.3 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DDE_Tnp_4 PF13359.6 GAM19007.1 - 2.3e-23 82.6 0.4 1.2e-21 77.1 0.3 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM19007.1 - 2.7e-08 33.7 1.9 4.7e-08 32.9 1.9 1.4 1 1 0 1 1 1 1 Transposase DDE domain DUF3772 PF12607.8 GAM19008.1 - 0.0022 17.7 1.5 0.0057 16.4 1.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3772) Rap_GAP PF02145.15 GAM19009.1 - 4.9e-35 120.8 0.1 1e-34 119.7 0.1 1.6 1 0 0 1 1 1 1 Rap/ran-GAP GREB1 PF15782.5 GAM19009.1 - 6.1 3.8 21.6 9.1 3.2 21.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RhoGAP PF00620.27 GAM19010.1 - 1.6e-30 106.0 2.5 1.7e-30 105.9 0.3 2.2 2 0 0 2 2 2 1 RhoGAP domain Androgen_recep PF02166.16 GAM19010.1 - 0.026 13.4 5.7 0.048 12.5 5.7 1.4 1 0 0 1 1 1 0 Androgen receptor CtsR PF05848.11 GAM19010.1 - 0.058 13.3 0.1 7.6 6.5 0.1 3.2 2 0 0 2 2 2 0 CtsR N-terminal HTH domain Rrf2 PF02082.20 GAM19010.1 - 0.062 13.7 1.4 0.29 11.5 0.2 2.4 2 0 0 2 2 2 0 Transcriptional regulator Rep_fac-A_C PF08646.10 GAM19010.1 - 2.4 7.9 8.1 0.92 9.2 1.2 2.4 2 0 0 2 2 2 0 Replication factor-A C terminal domain Nod1 PF17114.5 GAM19010.1 - 5.8 7.1 7.9 1.2 9.2 0.3 3.1 3 0 0 3 3 3 0 Gef2-related medial cortical node protein Nod1 MIT PF04212.18 GAM19011.1 - 4.9e-06 26.5 0.4 9.1e-06 25.7 0.4 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_10 PF17872.1 GAM19011.1 - 0.05 13.7 2.0 0.52 10.5 0.1 2.4 1 1 1 2 2 2 0 AAA lid domain NRBF2_MIT PF17169.4 GAM19011.1 - 0.062 13.5 0.5 0.22 11.8 0.5 2.0 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 DUF3439 PF11921.8 GAM19011.1 - 0.15 12.0 3.3 0.28 11.2 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2935 PF11155.8 GAM19011.1 - 0.53 10.6 4.6 0.52 10.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) zf-C4H2 PF10146.9 GAM19011.1 - 0.78 10.0 8.9 0.42 10.9 5.4 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein PNISR PF15996.5 GAM19012.1 - 0.006 16.9 6.2 0.006 16.9 6.2 1.4 2 0 0 2 2 2 1 Arginine/serine-rich protein PNISR DUF1953 PF09196.10 GAM19012.1 - 0.044 13.6 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) WD40 PF00400.32 GAM19013.1 - 5.3e-36 122.0 3.4 1.5e-08 35.2 0.5 10.5 10 0 0 10 10 10 6 WD domain, G-beta repeat Utp12 PF04003.12 GAM19013.1 - 4.7e-26 91.2 0.0 7.6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 GAM19013.1 - 5e-25 87.6 0.1 0.022 15.0 0.0 8.8 4 3 5 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM19013.1 - 1.3e-06 27.9 0.1 0.0075 15.6 0.0 4.8 3 1 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 GAM19013.1 - 3.1e-05 23.1 0.4 0.16 10.9 0.0 4.2 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAM19013.1 - 0.00011 22.0 0.0 10 6.2 0.0 5.2 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Utp21 PF04192.12 GAM19013.1 - 0.0005 19.6 0.2 0.00077 19.0 0.2 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain Nbas_N PF15492.6 GAM19013.1 - 0.0021 17.5 0.1 7 5.9 0.0 4.0 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 GAM19013.1 - 0.006 15.7 0.0 0.38 9.8 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) ELYS-bb PF16687.5 GAM19013.1 - 0.0072 15.0 0.1 0.04 12.5 0.0 2.0 2 0 0 2 2 2 1 beta-propeller of ELYS nucleoporin Med16 PF11635.8 GAM19013.1 - 0.035 12.0 0.0 4.5 5.1 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 16 Coatomer_WDAD PF04053.14 GAM19013.1 - 0.055 12.5 0.1 6.3 5.7 0.0 3.5 4 1 0 4 4 4 0 Coatomer WD associated region PQQ_3 PF13570.6 GAM19013.1 - 0.085 13.4 2.3 0.48 11.0 0.1 3.4 3 0 0 3 3 3 0 PQQ-like domain DUF3316 PF11777.8 GAM19013.1 - 0.088 12.9 0.2 2.1 8.4 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3316) Med4 PF10018.9 GAM19014.1 - 1.3e-26 93.5 3.7 1.3e-26 93.5 3.7 2.6 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 NAGLU_C PF12972.7 GAM19014.1 - 0.35 10.3 9.9 0.03 13.9 3.2 2.2 2 1 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain AAA_23 PF13476.6 GAM19014.1 - 0.61 10.6 9.3 0.49 10.9 1.1 2.4 2 0 0 2 2 2 0 AAA domain TMEM65 PF10507.9 GAM19014.1 - 0.85 9.6 2.7 0.51 10.3 0.2 1.9 2 0 0 2 2 2 0 Transmembrane protein 65 MAM33 PF02330.16 GAM19015.1 - 3.6e-10 40.2 19.3 5.1e-05 23.3 15.2 3.0 2 1 0 2 2 2 2 Mitochondrial glycoprotein FmiP_Thoc5 PF09766.9 GAM19015.1 - 0.00051 19.4 3.1 0.00067 19.1 3.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 FixO PF02433.15 GAM19015.1 - 0.056 12.9 1.1 0.094 12.2 1.1 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO RNase_H2_suC PF08615.11 GAM19015.1 - 0.09 13.0 2.2 0.61 10.3 2.5 1.9 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Presenilin PF01080.17 GAM19015.1 - 0.26 10.0 1.3 0.3 9.8 1.3 1.1 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 GAM19015.1 - 0.26 10.7 12.4 0.32 10.4 12.4 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 GAM19015.1 - 1.3 8.3 19.0 2 7.7 19.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 GAM19015.1 - 4.2 5.5 17.4 4.9 5.2 17.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4175 PF13779.6 GAM19015.1 - 5.5 4.8 8.6 7.1 4.4 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pkinase_Tyr PF07714.17 GAM19016.1 - 7.3e-56 189.3 0.0 1.1e-55 188.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM19016.1 - 4.5e-54 183.6 0.0 7.5e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.19 GAM19016.1 - 2.8e-41 141.6 0.0 5.7e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM19016.1 - 8.1e-19 67.8 1.7 3e-18 66.0 1.7 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif Haspin_kinase PF12330.8 GAM19016.1 - 6e-06 25.4 0.1 1e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 GAM19016.1 - 0.013 14.5 0.7 2.5 7.0 0.2 2.3 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 GAM19016.1 - 0.022 14.1 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM19016.1 - 0.029 13.2 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase NAD_Gly3P_dh_N PF01210.23 GAM19016.1 - 0.034 14.1 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Kinase-like PF14531.6 GAM19016.1 - 0.057 12.7 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GAM19016.1 - 0.074 13.0 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM19016.1 - 0.11 12.1 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase THEG4 PF15834.5 GAM19016.1 - 1.1 9.2 3.7 3.1 7.7 2.0 2.3 2 0 0 2 2 2 0 Testis highly expressed protein 4 NUDIX PF00293.28 GAM19017.1 - 2.5e-06 27.6 0.2 8.2e-05 22.7 0.2 2.7 1 1 0 1 1 1 1 NUDIX domain FYVE PF01363.21 GAM19018.1 - 8e-09 35.5 5.9 1.5e-08 34.6 5.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 GAM19018.1 - 0.00067 19.9 3.6 0.00067 19.9 3.6 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger Syntaxin_2 PF14523.6 GAM19018.1 - 0.031 14.6 5.1 0.082 13.3 1.1 2.6 2 0 0 2 2 2 0 Syntaxin-like protein Sec8_exocyst PF04048.14 GAM19018.1 - 0.075 12.9 1.6 0.14 12.1 0.5 1.9 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF3516 PF12029.8 GAM19018.1 - 0.08 12.0 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Syntaxin PF00804.25 GAM19018.1 - 0.094 12.4 1.1 0.19 11.4 1.1 1.6 1 0 0 1 1 1 0 Syntaxin Focal_AT PF03623.13 GAM19018.1 - 0.16 12.0 2.5 2.8 7.9 0.1 2.6 2 1 0 2 2 2 0 Focal adhesion targeting region IBR PF01485.21 GAM19018.1 - 0.19 12.0 5.3 0.57 10.5 5.3 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain C1_2 PF03107.16 GAM19018.1 - 2.9 8.3 6.2 3.8 7.9 4.4 2.0 2 0 0 2 2 2 0 C1 domain DUF1258 PF06869.12 GAM19018.1 - 7.5 5.9 8.4 0.26 10.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) HA2 PF04408.23 GAM19019.1 - 3.7e-21 75.4 0.0 9.2e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAM19019.1 - 1.9e-17 63.4 0.0 5e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAM19019.1 - 1.5e-12 47.8 0.1 5.5e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM19019.1 - 1.5e-07 31.3 0.1 4e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAM19019.1 - 1.1e-05 25.7 0.0 3.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM19019.1 - 4.1e-05 23.9 0.1 9.3e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM19019.1 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain PSK_trans_fac PF07704.11 GAM19019.1 - 0.012 16.3 0.3 4.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Rv0623-like transcription factor ABC_tran PF00005.27 GAM19019.1 - 0.018 15.6 0.2 0.19 12.2 0.2 2.4 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 GAM19019.1 - 0.039 13.6 0.5 0.23 11.1 0.1 2.4 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 GAM19019.1 - 0.042 13.8 0.1 0.082 12.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_7 PF12775.7 GAM19019.1 - 0.057 12.9 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region ILEI PF15711.5 GAM19020.1 - 6.3e-50 167.6 9.3 1.3e-14 54.5 0.2 4.3 4 0 0 4 4 4 4 Interleukin-like EMT inducer Cellulose_synt PF03552.14 GAM19021.1 - 1.9e-23 82.9 11.4 2.6e-15 56.0 1.7 3.5 3 1 1 4 4 4 3 Cellulose synthase Glyco_trans_2_3 PF13632.6 GAM19021.1 - 1.2e-20 74.3 0.1 1.2e-20 74.3 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAM19021.1 - 1.7e-15 57.5 0.0 3.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAM19021.1 - 1.4e-10 41.2 0.0 6.1e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAM19021.1 - 7.7e-07 28.7 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Di19_C PF14571.6 GAM19021.1 - 0.015 15.8 0.3 1.8 9.1 0.0 2.6 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Pentapeptide PF00805.22 GAM19022.1 - 7e-27 92.7 22.8 1.2e-09 37.6 1.2 4.2 1 1 3 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 GAM19022.1 - 4.1e-18 65.3 2.2 5e-10 39.4 0.1 2.7 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 GAM19022.1 - 1.9e-14 53.7 0.0 3.7e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.6 GAM19022.1 - 4.8e-11 42.6 0.1 5.9e-05 23.1 0.0 3.0 2 1 0 2 2 2 2 Pentapeptide repeats (9 copies) CfAFP PF05264.11 GAM19022.1 - 0.051 13.6 0.3 0.051 13.6 0.3 2.3 2 1 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) LptF_LptG PF03739.14 GAM19023.1 - 0.0017 17.3 0.2 0.002 17.1 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG DUF2371 PF10177.9 GAM19023.1 - 0.04 14.1 0.4 0.1 12.8 0.4 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Sigma_reg_N PF13800.6 GAM19023.1 - 0.13 12.6 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal WBP-1 PF11669.8 GAM19023.1 - 0.15 12.7 3.3 0.22 12.2 0.1 1.9 1 1 1 2 2 2 0 WW domain-binding protein 1 SUIM_assoc PF16619.5 GAM19023.1 - 0.56 10.3 20.4 0.78 9.8 4.2 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 O-antigen_lig PF13425.6 GAM19023.1 - 0.92 8.2 2.4 0.94 8.2 2.4 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein EphA2_TM PF14575.6 GAM19023.1 - 0.94 10.4 4.6 3.6 8.5 4.6 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Sulfotransfer_2 PF03567.14 GAM19024.1 - 6e-13 49.3 0.5 1.4e-12 48.1 0.5 1.6 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 GAM19024.1 - 2.4e-09 36.6 2.9 2.3e-08 33.4 0.4 2.8 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase Tmemb_9 PF05434.11 GAM19024.1 - 0.078 12.9 0.2 0.078 12.9 0.2 1.8 2 0 0 2 2 2 0 TMEM9 Sulfotransfer_1 PF00685.27 GAM19024.1 - 0.23 10.9 2.9 0.44 10.0 0.4 2.5 2 1 0 2 2 2 0 Sulfotransferase domain UCH_1 PF13423.6 GAM19025.1 - 2.6e-77 260.6 19.7 2.6e-77 260.6 19.7 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 GAM19025.1 - 4.6e-22 79.3 1.4 3.6e-21 76.4 0.0 2.8 3 0 0 3 3 3 1 Exonuclease TFIIA PF03153.13 GAM19025.1 - 0.00053 20.1 46.7 0.014 15.4 24.7 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Velvet PF11754.8 GAM19025.1 - 0.001 19.1 15.6 0.14 12.0 3.6 2.7 2 0 0 2 2 2 2 Velvet factor Pex14_N PF04695.13 GAM19025.1 - 0.71 10.5 45.0 4.4 8.0 11.7 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MMR1 PF08505.10 GAM19025.1 - 1.6 8.9 23.4 6.2 7.0 9.0 2.8 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Band_3_cyto PF07565.13 GAM19025.1 - 1.8 8.3 14.8 5.1 6.8 2.9 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain EPL1 PF10513.9 GAM19025.1 - 2.1 8.7 22.7 0.21 12.0 4.4 3.1 3 0 0 3 3 3 0 Enhancer of polycomb-like PAT1 PF09770.9 GAM19025.1 - 3.2 5.9 37.9 2.8 6.1 9.9 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 YjeF_N PF03853.15 GAM19025.1 - 3.9 7.3 6.6 0.16 11.9 0.3 1.9 2 0 0 2 2 1 0 YjeF-related protein N-terminus DUF5308 PF17233.2 GAM19025.1 - 5.6 7.2 16.1 0.14 12.4 1.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5308) DUF4757 PF15949.5 GAM19025.1 - 6.2 7.3 21.0 0.072 13.6 4.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) Zip PF02535.22 GAM19025.1 - 9.4 5.3 10.4 0.12 11.5 1.3 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter DDE_3 PF13358.6 GAM19026.1 - 1.6e-19 70.1 0.0 2.1e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Dickkopf_N PF04706.12 GAM19028.1 - 5.5e-05 23.6 4.6 5.5e-05 23.6 4.6 5.9 3 2 3 6 6 6 3 Dickkopf N-terminal cysteine-rich region TMEM154 PF15102.6 GAM19029.1 - 1.4e-07 31.5 1.1 6.1e-07 29.4 1.1 1.9 1 1 0 1 1 1 1 TMEM154 protein family NOA36 PF06524.12 GAM19029.1 - 0.025 13.9 8.3 0.033 13.5 8.3 1.1 1 0 0 1 1 1 0 NOA36 protein Protocadherin PF08374.11 GAM19029.1 - 0.034 14.1 0.0 0.034 14.1 0.0 2.7 3 0 0 3 3 3 0 Protocadherin DAG1 PF05454.11 GAM19029.1 - 0.039 13.3 3.7 0.058 12.8 3.3 1.6 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 GAM19029.1 - 0.064 14.1 0.6 0.26 12.2 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2755 PF10954.8 GAM19029.1 - 0.55 10.2 3.5 1 9.3 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) zf-CCHH PF10283.9 GAM19030.1 - 0.36 10.9 3.7 0.49 10.4 0.2 2.7 2 0 0 2 2 2 0 PBZ domain AMP-binding PF00501.28 GAM19031.1 - 3.8e-98 328.9 0.0 4.7e-98 328.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM19031.1 - 2.3e-18 66.9 0.0 9.8e-18 64.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Anoctamin PF04547.12 GAM19032.1 - 1.4e-93 314.2 21.4 1.9e-93 313.7 21.4 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel TMEM107 PF14995.6 GAM19033.1 - 0.015 15.8 1.6 0.032 14.7 1.6 1.5 1 1 0 1 1 1 0 Transmembrane protein Ion_trans PF00520.31 GAM19033.1 - 0.022 14.0 3.1 0.46 9.7 0.2 2.5 2 1 0 2 2 2 0 Ion transport protein MHYT PF03707.16 GAM19033.1 - 0.037 14.2 0.4 0.86 9.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat DUF2371 PF10177.9 GAM19033.1 - 0.093 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DHHC PF01529.20 GAM19033.1 - 0.098 12.8 2.5 0.15 12.2 2.5 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Claudin_2 PF13903.6 GAM19033.1 - 0.47 10.2 3.8 0.15 11.8 0.5 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction FNIP PF05725.12 GAM19034.1 - 2.4e-95 312.5 15.7 2e-14 53.5 0.1 9.6 8 1 0 9 9 9 9 FNIP Repeat TRAPP PF04051.16 GAM19035.1 - 4.3e-42 143.3 0.0 5.2e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FoP_duplication PF13865.6 GAM19036.1 - 1.2e-06 29.0 20.1 1.2e-06 29.0 20.1 3.1 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 SNF2_N PF00176.23 GAM19037.1 - 3e-72 243.3 0.5 5.4e-72 242.4 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAM19037.1 - 9.4e-35 119.1 1.8 9.4e-35 119.1 1.8 3.7 3 1 0 3 3 3 1 SLIDE Helicase_C PF00271.31 GAM19037.1 - 2.6e-20 72.8 0.9 1.6e-19 70.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HAND PF09110.11 GAM19037.1 - 7.3e-15 55.7 4.4 7.3e-15 55.7 4.4 5.0 3 1 0 3 3 3 1 HAND ResIII PF04851.15 GAM19037.1 - 2.2e-08 34.3 0.0 2.2e-08 34.3 0.0 3.6 4 1 0 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM19037.1 - 7.2e-06 25.9 0.0 2.9e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 GAM19037.1 - 5.2e-05 22.6 0.0 5.2e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DBINO PF13892.6 GAM19037.1 - 0.00011 22.6 16.6 0.00011 22.6 16.6 4.2 3 1 1 4 4 4 1 DNA-binding domain SlyX PF04102.12 GAM19037.1 - 0.3 11.7 0.0 0.3 11.7 0.0 4.8 5 0 0 5 5 5 0 SlyX DUF2605 PF10792.9 GAM19037.1 - 3.7 7.5 8.5 31 4.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) Ribosomal_L34 PF00468.17 GAM19038.1 - 4.7e-17 61.7 6.0 6.9e-17 61.2 6.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Tox-MPTase3 PF15639.6 GAM19038.1 - 0.0018 18.1 0.2 0.003 17.4 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase toxin 3 zf-CSL PF05207.13 GAM19039.1 - 2.8e-18 65.4 2.7 4.7e-18 64.7 2.7 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 GAM19039.1 - 2.3e-17 62.8 0.4 3.9e-17 62.1 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain CLU PF13236.6 GAM19040.1 - 1.7e-84 283.1 0.0 3.4e-84 282.1 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAM19040.1 - 3.1e-45 154.4 0.4 3.1e-45 154.4 0.4 3.1 3 1 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 GAM19040.1 - 3.3e-29 101.0 2.5 8.1e-12 45.3 0.0 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAM19040.1 - 8.2e-24 82.7 0.8 2.2e-09 36.9 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.6 GAM19040.1 - 3.4e-14 52.9 0.4 3.4e-14 52.9 0.4 2.3 3 0 0 3 3 1 1 Mitochondrial function, CLU-N-term TPR_2 PF07719.17 GAM19040.1 - 5.5e-08 32.3 8.3 0.013 15.6 0.2 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM19040.1 - 7.1e-07 28.8 8.2 0.12 12.2 0.3 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM19040.1 - 2.9e-06 26.9 4.8 6.6 7.0 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM19040.1 - 4.1e-05 23.5 11.1 0.22 11.8 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF727 PF05303.12 GAM19040.1 - 0.018 15.1 0.1 0.06 13.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF727) PH_14 PF17787.1 GAM19040.1 - 0.032 14.1 0.3 0.12 12.2 0.3 2.0 1 0 0 1 1 1 0 PH domain COG4 PF08318.12 GAM19040.1 - 0.035 13.2 1.9 0.11 11.6 1.9 1.8 1 0 0 1 1 1 0 COG4 transport protein CUB PF00431.20 GAM19040.1 - 0.12 12.8 0.3 23 5.4 0.1 2.7 2 0 0 2 2 2 0 CUB domain Glyco_hydro_4C PF11975.8 GAM19040.1 - 3.8 7.5 6.7 0.57 10.2 0.0 2.8 3 1 0 3 3 2 0 Family 4 glycosyl hydrolase C-terminal domain TPR_1 PF00515.28 GAM19041.1 - 1.7e-07 30.8 0.8 1.4e-05 24.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM19041.1 - 3.5e-07 29.8 0.2 0.0001 22.1 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM19041.1 - 5.3e-07 30.1 0.1 0.0022 18.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM19041.1 - 4.8e-05 23.3 0.1 0.094 13.0 0.0 3.4 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM19041.1 - 0.001 19.7 0.0 1.1 10.2 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM19041.1 - 0.0015 18.6 0.1 0.3 11.3 0.0 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat SUIM_assoc PF16619.5 GAM19041.1 - 0.01 15.9 0.9 0.01 15.9 0.9 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TPR_16 PF13432.6 GAM19041.1 - 0.015 16.0 0.0 1.2 9.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM19041.1 - 0.032 14.3 0.0 29 5.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM19041.1 - 0.034 14.2 0.2 1.6 8.8 0.0 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Inj_translocase PF16928.5 GAM19041.1 - 0.2 11.1 5.8 1.2 8.5 5.0 2.3 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome SWI-SNF_Ssr4 PF08549.10 GAM19041.1 - 2.2 6.8 7.3 3.6 6.1 7.3 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) PCNA_N PF00705.18 GAM19042.1 - 1.4e-05 24.8 1.9 1.6e-05 24.6 0.1 1.9 3 0 0 3 3 3 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 GAM19042.1 - 0.00036 20.1 3.3 0.00046 19.7 3.3 1.3 1 0 0 1 1 1 1 Rad9 zf-CCCH PF00642.24 GAM19043.1 - 0.0011 18.8 2.1 0.0025 17.7 2.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nitr_red_assoc PF09655.10 GAM19043.1 - 0.044 14.4 1.8 0.11 13.2 0.1 2.4 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) RNase_H2_suC PF08615.11 GAM19044.1 - 0.008 16.3 3.0 0.013 15.7 0.0 2.2 2 1 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) NuDC PF16273.5 GAM19044.1 - 0.13 12.8 5.3 0.23 12.0 5.3 1.5 1 0 0 1 1 1 0 Nuclear distribution C domain Ribosomal_L37ae PF01780.19 GAM19045.1 - 4e-41 139.0 9.0 4.5e-41 138.8 9.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 GAM19045.1 - 0.00095 19.1 1.2 0.0015 18.4 1.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 GAM19045.1 - 0.016 15.6 0.2 1.1 9.8 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_13 PF17977.1 GAM19045.1 - 0.032 14.4 2.7 0.046 13.9 2.7 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain A2L_zn_ribbon PF08792.10 GAM19045.1 - 0.046 13.4 1.5 7 6.5 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_2 PF03107.16 GAM19045.1 - 0.095 13.0 2.0 0.72 10.2 2.2 1.9 1 1 0 1 1 1 0 C1 domain zf-C4_ClpX PF06689.13 GAM19045.1 - 0.25 11.3 0.2 0.25 11.3 0.2 2.2 3 0 0 3 3 3 0 ClpX C4-type zinc finger G-gamma PF00631.22 GAM19046.1 - 0.0015 18.5 0.1 0.0042 17.1 0.1 1.8 1 0 0 1 1 1 1 GGL domain Spectrin PF00435.21 GAM19046.1 - 0.65 10.5 8.2 3.1 8.3 1.9 2.9 2 1 0 2 2 2 0 Spectrin repeat DUF4148 PF13663.6 GAM19047.1 - 0.37 11.0 1.7 0.69 10.1 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) LRR_9 PF14580.6 GAM19048.1 - 6.1e-15 55.1 1.5 1.6e-13 50.5 0.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 GAM19048.1 - 1.2e-09 38.3 12.8 0.00021 21.6 0.5 2.8 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM19048.1 - 1.2e-06 28.2 14.0 7.5e-05 22.4 4.2 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 GAM19048.1 - 0.49 10.6 10.1 9.1 6.6 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 GAM19048.1 - 0.63 10.8 11.6 33 5.6 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat UQ_con PF00179.26 GAM19050.1 - 2e-18 66.4 0.0 3.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.18 GAM19050.1 - 0.07 12.5 1.1 0.14 11.5 1.1 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others HSF_DNA-bind PF00447.17 GAM19051.1 - 6.4e-26 90.8 0.9 6.4e-26 90.8 0.9 3.6 4 1 0 4 4 4 1 HSF-type DNA-binding HEAT PF02985.22 GAM19052.1 - 1.8e-07 30.8 4.9 0.077 13.3 0.2 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 GAM19052.1 - 5.3e-06 26.7 0.0 6.5 7.2 0.0 5.9 5 1 1 6 6 6 1 HEAT repeats IFRD PF05004.13 GAM19052.1 - 0.00053 19.2 10.4 0.4 9.7 0.0 5.0 4 2 1 5 5 5 3 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 GAM19052.1 - 0.018 15.1 9.4 0.27 11.3 0.2 5.7 5 2 2 7 7 7 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAM19052.1 - 0.025 15.1 0.7 7.5 7.2 0.0 5.2 4 0 0 4 4 4 0 HEAT-like repeat ABA_GPCR PF12430.8 GAM19052.1 - 0.1 12.4 0.0 0.1 12.4 0.0 4.3 4 0 0 4 4 4 0 Abscisic acid G-protein coupled receptor PPIP5K2_N PF18086.1 GAM19054.1 - 1.1e-32 112.0 0.2 2.2e-32 111.1 0.2 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 GAM19054.1 - 0.00022 20.9 0.0 0.00042 20.0 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Nucleocapsid-N PF11030.8 GAM19055.1 - 0.32 10.9 10.2 1.5 8.7 0.2 2.2 2 0 0 2 2 2 0 Nucleocapsid protein N Nucleo_P87 PF07267.11 GAM19055.1 - 1.1 8.0 11.4 1.4 7.6 11.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AMP-binding PF00501.28 GAM19056.1 - 1.7e-97 326.7 0.0 2.2e-97 326.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM19056.1 - 1.4e-15 58.0 0.0 4.7e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ras PF00071.22 GAM19057.1 - 1.8e-39 135.0 0.2 2.2e-39 134.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM19057.1 - 2.6e-18 66.4 0.0 4.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM19057.1 - 6.1e-06 25.8 0.1 7e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM19057.1 - 0.00075 19.1 0.0 0.00087 18.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain bZIP_1 PF00170.21 GAM19058.1 - 2e-11 43.8 14.1 2e-11 43.8 14.1 3.1 3 0 0 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.17 GAM19058.1 - 6.1e-07 29.9 11.2 6.1e-07 29.9 11.2 3.1 3 0 0 3 3 3 1 bZIP Maf transcription factor bZIP_2 PF07716.15 GAM19058.1 - 0.00058 19.9 10.1 0.00058 19.9 10.1 2.2 2 0 0 2 2 2 1 Basic region leucine zipper UPF0184 PF03670.13 GAM19058.1 - 0.0067 16.8 1.8 0.0067 16.8 1.8 2.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0184) HALZ PF02183.18 GAM19058.1 - 0.051 13.8 3.2 0.16 12.2 2.1 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 GAM19058.1 - 5.7 7.4 8.6 0.43 11.0 1.0 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) U-box PF04564.15 GAM19059.1 - 4e-10 39.7 0.0 9.9e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 U-box domain Acetyltransf_1 PF00583.25 GAM19059.1 - 3.1e-08 33.8 0.0 6.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM19059.1 - 5e-08 32.9 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-rbx1 PF12678.7 GAM19059.1 - 1.9e-06 28.1 0.0 4.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAM19059.1 - 2.1e-06 28.0 0.0 5.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Ring finger domain Acetyltransf_7 PF13508.7 GAM19059.1 - 2.4e-06 27.9 0.0 5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C3HC4_2 PF13923.6 GAM19059.1 - 4.1e-06 26.5 0.0 8.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM19059.1 - 0.00012 22.0 0.0 0.00027 20.9 0.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 GAM19059.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 GAM19059.1 - 0.002 18.0 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FR47 PF08445.10 GAM19059.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein zf-C3HC4 PF00097.25 GAM19059.1 - 0.022 14.6 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAM19059.1 - 0.029 14.4 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Acetyltransf_3 PF13302.7 GAM19059.1 - 0.043 14.5 0.0 0.48 11.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-C3HC4_3 PF13920.6 GAM19059.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM19059.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain G-alpha PF00503.20 GAM19059.1 - 0.2 10.8 3.7 0.56 9.3 3.7 1.8 1 1 0 1 1 1 0 G-protein alpha subunit FlxA PF14282.6 GAM19059.1 - 1.6 8.7 17.1 0.069 13.1 5.7 2.6 2 0 0 2 2 2 0 FlxA-like protein Dicty_CAR PF05462.11 GAM19060.1 - 7.9e-10 38.4 23.1 1e-09 38.0 23.1 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 GAM19060.1 - 7.7e-05 22.1 18.2 0.00011 21.6 18.2 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 GAM19060.1 - 0.88 8.8 17.5 1.2 8.4 17.5 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) GST_N_2 PF13409.6 GAM19061.1 - 2.7e-20 72.4 0.0 4.9e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM19061.1 - 3.6e-10 39.7 0.0 1.6e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM19061.1 - 2.4e-05 24.5 0.1 5.3e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM19061.1 - 0.0001 22.6 0.0 0.0025 18.2 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM19061.1 - 0.00047 20.3 0.1 0.001 19.2 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAM19061.1 - 0.073 12.9 0.2 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM19061.1 - 0.12 12.8 0.0 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Coiled PF05710.12 GAM19062.1 - 0.45 11.4 18.0 0.68 10.8 18.0 1.3 1 1 0 1 1 1 0 Coiled coil RRM_1 PF00076.22 GAM19063.1 - 3.1e-15 55.7 0.0 5.4e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GAM19063.1 - 1.8e-07 30.9 2.7 4.5e-07 29.6 2.7 1.8 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 GAM19063.1 - 0.026 14.1 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1084 PF06454.11 GAM19064.1 - 8.1e-70 235.3 21.1 9.9e-70 235.0 21.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF2339 PF10101.9 GAM19064.1 - 0.0014 17.3 4.9 0.0022 16.7 4.9 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Arf PF00025.21 GAM19065.1 - 1.1e-66 223.6 0.1 1.2e-66 223.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM19065.1 - 1.8e-15 57.2 0.0 2.5e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM19065.1 - 2.2e-14 53.3 0.0 3.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAM19065.1 - 1e-13 51.2 0.1 1.1e-13 51.1 0.1 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAM19065.1 - 5.1e-10 39.0 1.9 1.6e-07 30.8 0.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAM19065.1 - 1.9e-08 34.0 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM19065.1 - 7.4e-06 26.0 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 GAM19065.1 - 0.011 14.7 0.1 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB 6PF2K PF01591.18 GAM19065.1 - 0.026 13.8 0.4 0.12 11.6 0.4 1.9 1 1 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.27 GAM19065.1 - 0.035 14.6 0.1 0.1 13.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Vmethyltransf PF01660.17 GAM19065.1 - 0.064 12.1 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral methyltransferase AAA_14 PF13173.6 GAM19065.1 - 0.13 12.2 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM19065.1 - 0.19 11.9 0.3 1.7 8.8 0.1 2.1 1 1 0 2 2 2 0 AAA domain Spc7 PF08317.11 GAM19066.1 - 0.0018 17.2 27.4 0.0018 17.2 27.4 6.4 2 2 6 8 8 8 3 Spc7 kinetochore protein DUF2353 PF09789.9 GAM19066.1 - 0.0057 16.0 5.7 0.0057 16.0 5.7 6.6 2 1 4 6 6 6 4 Uncharacterized coiled-coil protein (DUF2353) FNIP PF05725.12 GAM19067.1 - 1.7e-67 223.3 15.7 5.3e-13 48.9 0.5 9.1 7 2 1 9 9 9 8 FNIP Repeat PPR_1 PF12854.7 GAM19067.1 - 0.068 12.9 0.1 0.24 11.1 0.1 2.0 1 0 0 1 1 1 0 PPR repeat LRR_4 PF12799.7 GAM19067.1 - 0.26 11.8 9.5 3.7 8.1 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM19067.1 - 0.62 10.8 3.4 23 6.1 0.0 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat FNIP PF05725.12 GAM19068.1 - 3.7e-74 244.6 15.0 1.5e-13 50.7 0.0 9.2 7 1 0 8 8 8 8 FNIP Repeat Ras PF00071.22 GAM19069.1 - 1.8e-65 219.5 0.1 2.1e-65 219.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM19069.1 - 3e-35 121.0 0.0 4.9e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM19069.1 - 3e-15 56.1 0.1 3.9e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM19069.1 - 1.2e-05 25.0 0.1 4.1e-05 23.2 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAM19069.1 - 3.7e-05 23.2 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM19069.1 - 0.00011 22.2 0.0 0.00034 20.7 0.0 1.7 1 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM19069.1 - 0.00069 19.6 0.3 0.22 11.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase DUF3963 PF13124.6 GAM19069.1 - 0.0079 16.2 0.2 0.02 14.9 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3963) SRPRB PF09439.10 GAM19069.1 - 0.01 15.3 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MCM PF00493.23 GAM19069.1 - 0.024 13.8 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 GAM19069.1 - 0.043 13.6 0.1 0.13 12.0 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM19069.1 - 0.066 13.6 0.0 0.18 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 GAM19069.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DHHC PF01529.20 GAM19070.1 - 9.1e-23 80.8 26.1 1.2e-22 80.5 16.2 2.5 2 0 0 2 2 2 2 DHHC palmitoyltransferase DUF1272 PF06906.11 GAM19070.1 - 0.1 12.7 7.7 0.2 11.7 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) eIF3g PF12353.8 GAM19070.1 - 0.65 10.4 8.3 1.2 9.6 8.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Ni_hydr_CYTB PF01292.20 GAM19070.1 - 4.5 6.8 14.7 0.069 12.7 1.7 3.2 2 2 1 3 3 3 0 Prokaryotic cytochrome b561 Ank_2 PF12796.7 GAM19071.1 - 2.3e-43 146.6 7.6 1.4e-14 54.4 0.4 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM19071.1 - 9e-33 111.9 4.4 8.4e-11 41.9 0.6 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19071.1 - 2e-28 95.3 0.7 0.00044 20.5 0.0 6.1 5 0 0 5 5 5 5 Ankyrin repeat DHHC PF01529.20 GAM19071.1 - 2.8e-28 98.7 8.3 2.8e-28 98.7 8.3 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.30 GAM19071.1 - 1.5e-26 91.7 0.3 0.0005 20.4 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 GAM19071.1 - 1.9e-24 85.7 4.7 1.4e-11 44.6 0.1 4.8 2 1 2 5 5 5 4 Ankyrin repeats (many copies) CTXphi_pIII-N1 PF16710.5 GAM19071.1 - 0.05 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Ncstrn_small PF18266.1 GAM19072.1 - 5.4e-31 107.9 0.0 3.3e-30 105.3 0.0 2.1 2 0 0 2 2 2 1 Nicastrin small lobe Nicastrin PF05450.15 GAM19072.1 - 1.5e-30 106.4 2.1 2.7e-30 105.6 2.1 1.3 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 GAM19072.1 - 6.2e-06 26.0 0.1 1e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Dickkopf_N PF04706.12 GAM19072.1 - 0.036 14.6 0.9 0.036 14.6 0.9 1.9 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Rap_GAP PF02145.15 GAM19073.1 - 2.2e-37 128.4 1.0 2.5e-36 125.0 0.1 2.4 2 0 0 2 2 2 1 Rap/ran-GAP Abhydrolase_1 PF00561.20 GAM19074.1 - 4e-25 88.9 0.0 1.3e-19 70.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM19074.1 - 5.4e-15 56.6 0.0 6.4e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM19074.1 - 9.4e-15 54.5 0.0 1.8e-14 53.6 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 GAM19074.1 - 9.8e-06 25.3 0.0 0.011 15.3 0.0 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 GAM19074.1 - 1e-05 25.6 0.1 4.5e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 GAM19074.1 - 0.0048 16.6 0.0 0.0093 15.6 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 GAM19074.1 - 0.0051 16.9 0.0 0.017 15.3 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 GAM19074.1 - 0.0067 16.3 0.1 0.034 14.0 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 GAM19074.1 - 0.011 15.6 0.0 0.082 12.8 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ndr PF03096.14 GAM19074.1 - 0.035 12.8 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family ALGX PF16822.5 GAM19074.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX LRR_6 PF13516.6 GAM19075.1 - 5.1e-20 69.8 36.6 0.0019 18.1 0.0 11.1 11 0 0 11 11 11 7 Leucine Rich repeat LRR_8 PF13855.6 GAM19075.1 - 5.8 6.8 37.4 0.99 9.2 0.8 8.5 5 2 2 7 7 7 0 Leucine rich repeat Ank_2 PF12796.7 GAM19076.1 - 6.8e-49 164.4 1.8 8.9e-16 58.3 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19076.1 - 7.1e-35 118.9 0.5 2.3e-08 34.4 0.0 6.0 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM19076.1 - 9.6e-30 102.3 4.9 4.8e-08 33.1 0.2 6.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM19076.1 - 1.4e-28 98.0 4.6 2.4e-07 30.9 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 GAM19076.1 - 8e-28 93.4 6.7 1.4e-05 25.1 0.0 8.8 9 0 0 9 9 9 5 Ankyrin repeat MATH PF00917.26 GAM19076.1 - 8.9e-25 87.1 4.2 1.1e-11 44.9 1.0 3.1 2 0 0 2 2 2 2 MATH domain TFIIA PF03153.13 GAM19076.1 - 1 9.3 20.5 0.56 10.2 4.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Med11 PF10280.9 GAM19077.1 - 4.4e-09 36.9 0.1 4.7e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein GRAS PF03514.14 GAM19077.1 - 0.059 12.3 0.1 0.069 12.1 0.1 1.1 1 0 0 1 1 1 0 GRAS domain family Pkinase PF00069.25 GAM19078.1 - 1.1e-51 175.7 0.4 2.7e-51 174.5 0.4 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19078.1 - 2.5e-31 108.9 0.1 4.4e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ANTH PF07651.16 GAM19078.1 - 6.1e-13 48.4 3.6 2.8e-12 46.2 2.2 2.3 2 0 0 2 2 2 1 ANTH domain Kinase-like PF14531.6 GAM19078.1 - 1.2e-05 24.7 0.0 0.00022 20.6 0.0 2.3 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 GAM19078.1 - 5.3e-05 23.3 0.0 0.028 14.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GAM19078.1 - 0.00025 20.5 1.1 0.00048 19.5 1.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.13 GAM19078.1 - 0.054 13.5 24.1 0.38 10.7 8.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Synaptobrevin PF00957.21 GAM19079.1 - 6.2e-30 102.8 6.5 6.9e-30 102.7 6.5 1.0 1 0 0 1 1 1 1 Synaptobrevin Ferlin_C PF16165.5 GAM19079.1 - 0.0028 17.6 2.4 0.003 17.5 1.8 1.3 1 1 0 1 1 1 1 Ferlin C-terminus Orf78 PF06024.12 GAM19079.1 - 0.0039 17.4 3.2 0.006 16.9 3.2 1.4 1 1 0 1 1 1 1 Orf78 (ac78) LMBR1 PF04791.16 GAM19079.1 - 0.0075 15.2 0.9 0.0083 15.1 0.9 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein EVI2A PF05399.11 GAM19079.1 - 0.012 15.3 0.3 0.013 15.1 0.3 1.0 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) UPF0258 PF06789.12 GAM19079.1 - 0.013 15.7 7.3 0.017 15.2 7.3 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF3675 PF12428.8 GAM19079.1 - 0.014 16.0 0.1 0.018 15.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) TACC_C PF05010.14 GAM19079.1 - 0.021 14.6 2.8 0.025 14.4 2.8 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal RIFIN PF02009.16 GAM19079.1 - 0.031 14.2 2.2 0.033 14.1 2.2 1.0 1 0 0 1 1 1 0 Rifin AAA_17 PF13207.6 GAM19079.1 - 0.072 13.5 0.2 0.085 13.3 0.2 1.1 1 0 0 1 1 1 0 AAA domain ODV-E18 PF10717.9 GAM19079.1 - 0.11 12.4 1.3 0.16 11.9 1.3 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2207 PF09972.9 GAM19079.1 - 0.11 11.2 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sigma_reg_N PF13800.6 GAM19079.1 - 1 9.7 7.5 2.2 8.6 7.5 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Prominin PF05478.11 GAM19079.1 - 4.2 5.2 9.7 6.8 4.5 9.7 1.4 1 1 0 1 1 1 0 Prominin SMC_Nse1 PF07574.13 GAM19080.1 - 3.8e-20 72.6 5.5 7.5e-16 58.6 3.6 2.1 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 GAM19080.1 - 0.0015 18.8 9.7 0.0015 18.8 9.7 2.6 3 1 0 3 3 3 1 RING-like domain Cytochrom_C550 PF14495.6 GAM19080.1 - 0.03 14.0 0.3 0.03 14.0 0.3 2.1 2 2 2 4 4 4 0 Cytochrome c-550 domain zf-RING_2 PF13639.6 GAM19080.1 - 0.039 14.3 9.9 0.039 14.3 9.9 1.9 2 0 0 2 2 2 0 Ring finger domain RraB PF06877.11 GAM19080.1 - 0.064 14.0 0.0 0.17 12.7 0.0 1.7 1 0 0 1 1 1 0 Regulator of ribonuclease activity B zf-C4H2 PF10146.9 GAM19080.1 - 0.12 12.7 5.1 0.19 12.0 5.1 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein zf-RING_9 PF13901.6 GAM19080.1 - 8.7 6.3 17.3 6.2 6.7 10.3 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon COPI_assoc PF08507.10 GAM19081.1 - 5.6e-10 39.4 12.5 4.4e-09 36.5 12.5 2.0 1 1 0 1 1 1 1 COPI associated protein DUF308 PF03729.13 GAM19081.1 - 0.0029 17.9 10.2 0.19 12.1 3.3 2.3 2 0 0 2 2 2 2 Short repeat of unknown function (DUF308) Dicty_CAR PF05462.11 GAM19082.1 - 4e-11 42.6 22.4 6.8e-11 41.8 22.4 1.3 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 GAM19082.1 - 7e-09 35.3 20.2 1.2e-08 34.6 20.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 GAM19082.1 - 1.1e-06 28.0 21.5 0.0014 17.7 13.6 2.3 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region GPR_Gpa2_C PF11970.8 GAM19082.1 - 0.021 14.9 0.6 0.021 14.9 0.6 2.4 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 GAM19082.1 - 0.11 11.8 23.4 0.32 10.3 23.4 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1681 PF07933.14 GAM19083.1 - 6.1e-55 185.0 0.0 8.9e-55 184.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Suf PF05843.14 GAM19083.1 - 1.8 8.5 7.6 2.4 8.1 7.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PIG-F PF06699.11 GAM19084.1 - 1.3e-35 123.2 7.2 1.7e-35 122.8 7.2 1.3 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2530 PF10745.9 GAM19084.1 - 2.7 8.3 5.1 7.4 6.9 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) RNase_T PF00929.24 GAM19085.1 - 2.1e-28 99.9 0.0 3.2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Spt5_N PF11942.8 GAM19087.1 - 5.4 8.1 31.2 1.9 9.5 3.9 2.9 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Hydrolase_3 PF08282.12 GAM19088.1 - 2.3e-61 207.8 0.1 2.7e-61 207.6 0.1 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 GAM19088.1 - 8e-09 35.4 0.0 0.00046 19.8 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 GAM19088.1 - 5.6e-07 30.1 0.2 3.7e-06 27.4 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAM19088.1 - 0.00015 22.3 0.1 3.1 8.1 0.0 3.2 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAM19088.1 - 0.0005 20.2 0.2 0.014 15.5 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GAM19088.1 - 0.065 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.32 GAM19089.1 - 5.1e-22 77.8 12.9 0.00015 22.5 0.0 8.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM19089.1 - 2.2e-10 40.7 1.4 0.27 11.5 0.0 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM19089.1 - 2.5e-07 30.3 0.2 1.6e-06 27.7 0.1 2.3 1 1 1 2 2 2 1 WD40-like domain zf-C3HC4_2 PF13923.6 GAM19089.1 - 8.3e-06 25.5 1.7 2.1e-05 24.3 1.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM19089.1 - 0.00012 21.9 2.7 0.0004 20.2 2.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAM19089.1 - 0.0002 21.4 1.2 0.00052 20.1 1.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GAM19089.1 - 0.00021 21.2 2.6 0.00056 19.9 2.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAM19089.1 - 0.0021 17.8 0.7 0.0053 16.6 0.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 GAM19089.1 - 0.035 13.9 6.1 0.61 9.9 2.3 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_5 PF14634.6 GAM19089.1 - 0.13 12.3 2.5 0.41 10.6 2.5 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 GAM19089.1 - 0.41 11.0 5.9 0.064 13.6 1.6 2.0 2 0 0 2 2 1 0 Ring finger domain SPX PF03105.19 GAM19089.1 - 0.89 9.4 36.6 0.034 14.1 29.4 1.9 1 1 1 2 2 1 0 SPX domain SET PF00856.28 GAM19090.1 - 1.2e-11 45.3 3.4 2e-11 44.6 0.5 2.4 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 GAM19090.1 - 1.5e-05 24.9 6.9 1.5e-05 24.9 6.9 2.4 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.7 GAM19090.1 - 0.014 16.6 0.5 0.014 16.6 0.5 1.7 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins VPS13_C PF16909.5 GAM19091.1 - 1.3e-57 194.4 4.5 8.3e-54 182.1 0.2 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 GAM19091.1 - 2.9e-42 144.9 5.2 2.2e-38 132.2 0.0 4.2 4 1 0 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 GAM19091.1 - 9e-36 123.8 0.5 9e-36 123.8 0.5 4.5 6 0 0 6 6 6 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 GAM19091.1 - 6.1e-29 100.5 0.1 6.1e-29 100.5 0.1 3.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 GAM19091.1 - 5.2e-10 39.5 0.0 2.2e-09 37.5 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain MqsR_toxin PF15723.5 GAM19091.1 - 0.13 12.7 0.2 0.38 11.1 0.2 1.8 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA Peptidase_C1 PF00112.23 GAM19093.1 - 5.7e-46 157.3 0.2 1e-45 156.5 0.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 GAM19093.1 - 9.3e-10 39.4 0.6 1.9e-09 38.5 0.6 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family LSM PF01423.22 GAM19094.1 - 1.2e-15 56.9 0.2 1.7e-15 56.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM19094.1 - 0.0009 19.3 0.0 0.0014 18.7 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 GAM19094.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 RimP C-terminal SH3 domain DUF1256 PF06866.11 GAM19094.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) AAA_2 PF07724.14 GAM19096.1 - 2.4e-40 138.4 0.1 1e-31 110.4 0.2 2.9 2 1 1 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAM19096.1 - 1.4e-13 51.4 0.0 2.5e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAM19096.1 - 1.1e-08 35.0 1.5 2.9e-08 33.7 0.2 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAM19096.1 - 3.1e-06 27.2 0.1 0.00017 21.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAM19096.1 - 6.9e-05 22.3 0.0 0.0035 16.8 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 GAM19096.1 - 0.00018 21.9 0.1 0.00093 19.6 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM19096.1 - 0.00036 20.8 0.7 0.0037 17.5 0.0 2.8 2 1 0 3 3 3 1 AAA domain MCM PF00493.23 GAM19096.1 - 0.0005 19.2 0.0 0.011 14.9 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 GAM19096.1 - 0.00086 19.0 0.0 0.046 13.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 GAM19096.1 - 0.0047 16.7 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAM19096.1 - 0.014 15.9 0.0 0.042 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAM19096.1 - 0.037 13.3 0.0 0.074 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 GAM19096.1 - 0.038 13.6 0.3 0.082 12.5 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 GAM19096.1 - 0.081 12.7 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 GAM19096.1 - 0.086 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 GAM19096.1 - 0.092 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAM19096.1 - 0.098 12.7 0.0 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 GAM19096.1 - 0.11 12.6 0.5 2.7 8.1 0.5 2.8 1 1 0 1 1 1 0 Shikimate kinase Apt1 PF10351.9 GAM19096.1 - 4.9 5.9 9.6 7.3 5.3 9.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain GCOM2 PF15328.6 GAM19096.1 - 8.5 6.7 10.2 1.6 9.0 5.5 2.1 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 Leg1 PF05612.12 GAM19097.1 - 1.9e-62 211.4 0.2 2.1e-62 211.2 0.2 1.0 1 0 0 1 1 1 1 Leg1 Myb_DNA-binding PF00249.31 GAM19098.1 - 3.8e-10 39.8 0.1 8.1e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM19098.1 - 4.3e-05 23.7 0.1 0.00014 22.0 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM19098.1 - 0.008 16.1 0.1 0.008 16.1 0.1 2.2 2 0 0 2 2 2 1 Myb DNA-binding like DUF3452 PF11934.8 GAM19098.1 - 0.047 13.3 0.2 0.13 11.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Peptidase_C1 PF00112.23 GAM19099.1 - 5.9e-54 183.4 2.7 9.8e-54 182.7 2.7 1.3 1 1 0 1 1 1 1 Papain family cysteine protease Kelch_4 PF13418.6 GAM19100.1 - 2.8e-11 43.3 0.1 0.00039 20.4 0.0 3.8 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM19100.1 - 4.8e-10 39.4 7.7 0.11 12.8 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 GAM19100.1 - 1.1e-05 25.1 2.6 0.029 14.3 0.1 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 GAM19100.1 - 1.2e-05 24.8 0.4 0.0035 16.9 0.1 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 GAM19100.1 - 0.0045 17.2 2.1 3.5 8.0 0.0 4.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM19100.1 - 0.018 15.1 3.0 3.4 7.7 0.1 3.2 3 0 0 3 3 3 0 Kelch motif FNIP PF05725.12 GAM19101.1 - 3.8e-27 94.2 28.2 2.5e-14 53.1 0.7 8.5 6 2 3 9 9 9 4 FNIP Repeat CS PF04969.16 GAM19102.1 - 5.2e-09 37.0 0.0 1.1e-08 35.9 0.0 1.5 2 0 0 2 2 2 1 CS domain Syndecan PF01034.20 GAM19103.1 - 0.082 12.8 3.4 0.2 11.6 3.4 1.6 1 0 0 1 1 1 0 Syndecan domain DUF4690 PF15756.5 GAM19103.1 - 0.11 13.1 1.4 0.25 12.0 1.4 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Protocadherin PF08374.11 GAM19103.1 - 0.16 11.9 1.3 0.27 11.2 1.3 1.3 1 0 0 1 1 1 0 Protocadherin Podoplanin PF05808.11 GAM19103.1 - 1.1 9.3 4.6 2 8.5 4.6 1.3 1 0 0 1 1 1 0 Podoplanin LRR_8 PF13855.6 GAM19104.1 - 3.5e-18 65.1 36.7 3.5e-09 36.3 7.6 5.1 4 2 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 GAM19104.1 - 3.9e-11 43.0 43.0 2.4e-05 24.6 6.1 5.2 2 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAM19104.1 - 1.3e-06 28.0 11.2 0.0026 17.3 0.5 2.7 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 GAM19104.1 - 0.017 15.1 32.8 0.26 11.4 2.0 7.4 7 0 0 7 7 7 0 Leucine Rich repeat Macoilin PF09726.9 GAM19104.1 - 0.83 8.1 25.2 0.0059 15.2 14.5 2.1 2 0 0 2 2 2 0 Macoilin family LRR_1 PF00560.33 GAM19104.1 - 2.2 9.2 34.4 2.9 8.8 1.1 7.7 6 1 0 6 6 6 0 Leucine Rich Repeat Peptidase_S9 PF00326.21 GAM19105.1 - 1.7e-46 158.4 0.0 4.3e-46 157.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 GAM19105.1 - 1.1e-32 113.4 4.0 1.9e-32 112.6 4.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S15 PF02129.18 GAM19105.1 - 0.032 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.12 GAM19105.1 - 0.14 12.1 0.2 0.42 10.6 0.2 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat HSP20 PF00011.21 GAM19106.1 - 1.5e-23 82.9 0.4 1.7e-23 82.7 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM19106.1 - 2.6e-10 39.7 0.0 4.2e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Myotub-related PF06602.14 GAM19107.1 - 6.2e-53 180.0 0.9 1.4e-52 178.8 0.3 1.9 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Pkinase_Tyr PF07714.17 GAM19107.1 - 6.2e-49 166.6 0.0 1.1e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM19107.1 - 1.4e-41 142.6 0.0 4.3e-41 141.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 GAM19107.1 - 4.8e-32 109.5 46.8 1.3e-07 31.3 4.5 6.8 2 1 2 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 GAM19107.1 - 7.7e-26 89.7 52.3 3.4e-06 27.3 0.4 8.8 5 1 4 10 10 10 9 Leucine Rich repeats (2 copies) RhoGAP PF00620.27 GAM19107.1 - 3.8e-18 65.8 0.0 1e-17 64.3 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain COR PF16095.5 GAM19107.1 - 3.6e-14 53.0 0.2 2.6e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain LRR_9 PF14580.6 GAM19107.1 - 2.3e-09 37.0 18.9 9.5e-07 28.5 0.9 3.9 1 1 2 3 3 3 2 Leucine-rich repeat Vps36_ESCRT-II PF11605.8 GAM19107.1 - 0.011 15.9 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 LRR_1 PF00560.33 GAM19107.1 - 0.2 12.3 51.6 5.7 7.9 0.1 12.7 12 1 0 12 12 12 0 Leucine Rich Repeat CorA PF01544.18 GAM19108.1 - 2.8e-59 200.8 4.5 3.4e-59 200.5 4.5 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Tyrosinase PF00264.20 GAM19110.1 - 9.9e-40 137.2 1.2 1.5e-39 136.6 1.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase TCTP PF00838.17 GAM19112.1 - 1e-55 188.6 4.9 1.1e-55 188.4 4.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein SCVP PF17619.2 GAM19112.1 - 0.13 13.1 1.0 0.24 12.3 0.1 1.9 2 1 0 2 2 2 0 Secreted clade V proteins E1-E2_ATPase PF00122.20 GAM19113.1 - 3.8e-50 169.9 1.3 3.8e-50 169.9 1.3 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAM19113.1 - 2.8e-18 67.0 0.0 6.9e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM19113.1 - 7.9e-13 47.9 0.0 2.9e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM19113.1 - 0.0012 18.7 1.2 0.0025 17.6 0.1 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 GAM19113.1 - 0.0031 17.2 0.3 0.0031 17.2 0.3 3.1 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GAM19113.1 - 0.0041 17.2 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Motilin_assoc PF04643.12 GAM19113.1 - 0.15 11.9 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide UPF0560 PF10577.9 GAM19116.1 - 1.7 7.1 34.6 0.045 12.3 13.2 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0560 CDO_I PF05995.12 GAM19117.1 - 8.6e-26 90.3 0.0 1.2e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 GAM19117.1 - 0.026 14.0 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 PCO_ADO Actin PF00022.19 GAM19120.1 - 2.7e-152 507.1 0.0 8.6e-152 505.5 0.0 1.6 1 1 0 1 1 1 1 Actin HAD_2 PF13419.6 GAM19121.1 - 2.7e-05 24.3 0.0 4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM19121.1 - 0.0029 17.9 0.0 0.0044 17.3 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DnaJ PF00226.31 GAM19122.1 - 3.8e-24 84.6 1.3 6.4e-24 83.9 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 GAM19122.1 - 0.00018 21.7 0.2 0.00053 20.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Hamartin PF04388.12 GAM19122.1 - 0.011 14.4 10.3 0.014 14.1 10.3 1.1 1 0 0 1 1 1 0 Hamartin protein TPR_2 PF07719.17 GAM19122.1 - 0.044 13.9 0.1 6.1 7.2 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Tmemb_cc2 PF10267.9 GAM19122.1 - 0.12 11.5 1.4 0.2 10.8 1.4 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein QWRF PF04484.12 GAM19122.1 - 0.12 12.1 3.2 0.18 11.5 3.2 1.2 1 0 0 1 1 1 0 QWRF family CCDC24 PF15669.5 GAM19122.1 - 0.38 10.6 4.7 0.66 9.8 4.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family NAM-associated PF14303.6 GAM19122.1 - 0.43 11.3 7.8 0.9 10.2 7.8 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF908 PF06012.12 GAM19122.1 - 0.54 9.6 8.2 0.78 9.1 8.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RAP1 PF07218.11 GAM19122.1 - 1.9 6.7 6.7 2.5 6.3 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ELFV_dehydrog_N PF02812.18 GAM19123.1 - 5e-57 191.4 0.0 8.5e-57 190.6 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 GAM19123.1 - 1.1e-56 192.3 0.3 3.4e-54 184.1 0.0 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.21 GAM19123.1 - 0.00046 20.3 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Bac_GDH PF05088.12 GAM19123.1 - 0.0013 16.4 0.0 0.21 9.1 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase 2-Hacid_dh_C PF02826.19 GAM19123.1 - 0.0029 17.0 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 GAM19123.1 - 0.0033 17.9 0.0 0.0071 16.8 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Phosphodiest PF01663.22 GAM19124.1 - 1.5e-65 222.2 1.7 7.2e-65 219.9 1.7 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAM19124.1 - 5.5e-06 26.0 0.8 1.9e-05 24.2 0.1 2.3 2 1 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 GAM19124.1 - 0.0061 15.9 0.8 0.027 13.8 0.0 2.1 3 0 0 3 3 3 1 Metalloenzyme superfamily DUF1501 PF07394.12 GAM19124.1 - 0.022 13.8 0.2 0.04 13.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) Afaf PF15339.6 GAM19124.1 - 0.045 13.5 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor PglZ PF08665.12 GAM19124.1 - 0.071 13.2 1.0 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 PglZ domain FNIP PF05725.12 GAM19125.1 - 4.8e-63 209.1 32.3 2.9e-13 49.7 0.7 7.9 6 2 1 8 8 8 7 FNIP Repeat FNIP PF05725.12 GAM19127.1 - 3.3e-16 59.1 11.4 0.00029 20.9 0.1 6.2 5 1 1 6 6 6 4 FNIP Repeat HHA PF05321.11 GAM19128.1 - 0.012 15.9 0.3 0.049 13.9 0.1 2.2 2 0 0 2 2 2 0 Haemolysin expression modulating protein DUF1601 PF07671.11 GAM19128.1 - 0.16 11.8 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) Ank_2 PF12796.7 GAM19128.1 - 0.82 10.3 5.5 19 5.9 0.1 4.3 3 2 2 5 5 5 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 GAM19129.1 - 0.047 14.3 8.1 1.2 9.7 0.1 4.4 3 2 1 4 4 4 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM19129.1 - 0.17 12.2 0.9 21 5.6 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeats (many copies) FKBP_C PF00254.28 GAM19131.1 - 3.2e-19 69.0 0.0 5.2e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 GAM19131.1 - 2.3e-09 36.7 6.4 8.9e-07 28.5 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM19131.1 - 2.5e-07 30.3 3.9 1.2e-06 28.2 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM19131.1 - 4.6e-07 29.5 3.4 5.4e-06 26.2 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAM19131.1 - 9.2e-05 22.1 0.2 0.098 12.4 0.1 3.3 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.6 GAM19131.1 - 0.0023 18.2 0.4 0.0072 16.6 0.4 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM19131.1 - 0.013 14.7 0.2 0.038 13.2 0.0 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAM19131.1 - 0.013 15.8 4.4 0.089 13.2 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM19131.1 - 0.02 15.7 0.1 0.074 13.9 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM19131.1 - 0.033 14.4 1.1 0.61 10.3 0.1 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FKBP_N_2 PF18023.1 GAM19131.1 - 0.047 13.8 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 BDBT FKBP like N-terminal TPR_19 PF14559.6 GAM19131.1 - 0.07 13.7 0.0 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM19131.1 - 0.097 13.3 2.1 0.47 11.2 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Vps55 PF04133.14 GAM19132.1 - 6.3e-31 106.8 6.5 7.4e-31 106.5 6.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Rax2 PF12768.7 GAM19132.1 - 0.083 12.3 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity FNIP PF05725.12 GAM19133.1 - 1.8e-10 40.8 11.4 0.0027 17.9 0.0 6.4 5 2 1 6 6 6 4 FNIP Repeat FNIP PF05725.12 GAM19134.1 - 1.8e-44 149.7 13.0 1.3e-10 41.2 0.0 6.8 5 2 1 6 6 6 6 FNIP Repeat LRR_11 PF18831.1 GAM19134.1 - 0.99 9.0 4.7 0.89 9.2 0.2 2.9 3 0 0 3 3 3 0 Leucine-rich repeat Med20 PF08612.11 GAM19135.1 - 2.5e-21 76.1 0.1 3.5e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ArgoMid PF16487.5 GAM19135.1 - 0.087 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Mid domain of argonaute SET PF00856.28 GAM19136.1 - 3e-10 40.7 0.0 3e-10 40.7 0.0 2.9 2 2 0 2 2 2 1 SET domain Ank_2 PF12796.7 GAM19137.1 - 7.4e-29 100.2 10.4 1.8e-06 28.4 0.2 5.2 1 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19137.1 - 6.2e-22 77.7 12.8 0.00011 22.7 0.0 8.2 3 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19137.1 - 7.2e-18 62.8 9.9 1 10.1 0.1 11.5 10 2 2 12 12 12 4 Ankyrin repeat Ank_5 PF13857.6 GAM19137.1 - 4.1e-16 58.8 12.3 0.19 12.1 0.0 10.4 5 3 6 11 11 11 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM19137.1 - 1.1e-08 35.1 6.1 0.81 10.3 0.6 6.8 5 2 0 5 5 5 2 Ankyrin repeat DUF3447 PF11929.8 GAM19137.1 - 1.7e-07 31.1 0.1 0.44 10.5 0.5 4.4 2 2 2 4 4 4 3 Domain of unknown function (DUF3447) DUF249 PF03158.13 GAM19137.1 - 0.099 12.3 1.9 3.9 7.1 0.1 3.6 2 1 1 3 3 3 0 Multigene family 530 protein Xin PF08043.12 GAM19137.1 - 6.6 6.5 5.7 11 5.8 0.3 2.9 3 0 0 3 3 3 0 Xin repeat RNaseH_C PF09293.10 GAM19138.1 - 0.085 13.2 0.1 0.28 11.5 0.0 1.9 1 1 1 2 2 2 0 T4 RNase H, C terminal LRR_4 PF12799.7 GAM19138.1 - 0.19 12.2 3.1 2.2 8.8 0.0 4.1 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) Peptidase_C1 PF00112.23 GAM19140.1 - 5.4e-18 65.9 0.1 8.1e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C39_2 PF13529.6 GAM19140.1 - 2.3e-06 28.2 0.0 5.7e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase_C39 like family DUF4240 PF14024.6 GAM19140.1 - 0.0098 16.1 0.5 0.26 11.5 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4240) BAR_3 PF16746.5 GAM19140.1 - 0.012 15.4 0.2 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 BAR domain of APPL family Peptidase_C47 PF05543.13 GAM19140.1 - 0.06 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 TerB PF05099.13 GAM19140.1 - 0.085 12.8 0.8 0.26 11.2 0.8 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TerB BACK PF07707.15 GAM19142.1 - 9.9e-10 38.5 0.5 2.5e-07 30.7 0.0 3.1 2 1 1 3 3 3 1 BTB And C-terminal Kelch BTB PF00651.31 GAM19142.1 - 1.9e-05 24.8 0.0 4.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 GAM19142.1 - 0.001 19.2 0.1 0.0025 18.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Sad1_UNC PF07738.13 GAM19142.1 - 0.0018 18.3 0.0 0.0052 16.8 0.0 1.8 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Otopetrin PF03189.13 GAM19142.1 - 0.003 16.4 0.1 0.0052 15.7 0.1 1.3 1 0 0 1 1 1 1 Otopetrin SPX PF03105.19 GAM19142.1 - 0.089 12.7 11.6 1 9.2 11.7 2.0 1 1 0 1 1 1 0 SPX domain DUF1631 PF07793.11 GAM19142.1 - 7.5 4.8 5.6 12 4.2 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) ACPS PF01648.20 GAM19143.1 - 2.4e-17 63.1 0.0 2.6e-14 53.3 0.0 2.5 3 0 0 3 3 3 2 4'-phosphopantetheinyl transferase superfamily DUF5643 PF18705.1 GAM19143.1 - 0.037 14.0 0.2 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5643) La PF05383.17 GAM19144.1 - 1.4e-24 85.9 0.1 3.5e-24 84.6 0.1 1.7 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 GAM19144.1 - 3.5e-24 84.8 2.0 2.6e-23 82.0 0.3 2.4 2 1 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 GAM19144.1 - 3.2e-10 39.7 2.0 3.2e-06 26.9 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM19144.1 - 0.0069 16.0 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.11 GAM19144.1 - 0.76 8.5 10.3 5 5.8 4.9 2.3 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) EXS PF03124.14 GAM19145.1 - 6.9e-87 291.9 25.5 9.1e-87 291.5 25.5 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 GAM19145.1 - 7.7e-33 114.9 26.7 2.8e-24 86.8 5.5 3.1 2 1 1 3 3 3 2 SPX domain Kelch_6 PF13964.6 GAM19146.1 - 0.0098 16.2 1.1 0.074 13.4 0.2 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 GAM19147.1 - 0.0043 17.3 2.6 0.11 12.8 0.0 3.6 4 0 0 4 4 4 1 Kelch motif AATF-Che1 PF13339.6 GAM19147.1 - 0.054 14.2 1.4 0.11 13.1 1.4 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Kelch_6 PF13964.6 GAM19148.1 - 0.13 12.6 0.1 2.4 8.6 0.0 2.7 3 0 0 3 3 3 0 Kelch motif MIEAP PF16026.5 GAM19149.1 - 0.005 17.1 0.1 0.023 14.9 0.1 2.0 1 1 1 2 2 2 2 Mitochondria-eating protein zf-B_box PF00643.24 GAM19149.1 - 0.0067 16.6 6.7 0.023 14.8 6.7 2.0 1 0 0 1 1 1 1 B-box zinc finger DUF1043 PF06295.12 GAM19149.1 - 0.21 11.6 1.5 0.42 10.6 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) PIN_4 PF13638.6 GAM19149.1 - 0.26 11.6 7.8 0.89 9.8 7.8 1.8 1 1 0 1 1 1 0 PIN domain Kelch_5 PF13854.6 GAM19149.1 - 0.76 9.8 6.3 44 4.2 0.3 3.9 3 1 0 3 3 3 0 Kelch motif zf-B_box PF00643.24 GAM19150.1 - 5.9e-08 32.7 4.6 5.9e-08 32.7 4.6 1.9 2 0 0 2 2 2 1 B-box zinc finger Fer2 PF00111.27 GAM19150.1 - 0.022 14.7 2.6 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain AATF-Che1 PF13339.6 GAM19150.1 - 0.16 12.6 1.5 0.33 11.6 1.5 1.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor ALMT PF11744.8 GAM19150.1 - 0.78 8.5 5.3 1.1 8.0 5.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-B_box PF00643.24 GAM19152.1 - 0.00019 21.5 6.9 0.00047 20.3 6.9 1.7 1 0 0 1 1 1 1 B-box zinc finger Kelch_6 PF13964.6 GAM19152.1 - 0.026 14.8 0.1 2.5 8.5 0.0 2.8 2 0 0 2 2 2 0 Kelch motif FNIP PF05725.12 GAM19153.1 - 2.7e-66 219.5 8.7 2.2e-13 50.1 0.2 8.6 5 2 5 10 10 10 9 FNIP Repeat F-box-like PF12937.7 GAM19153.1 - 0.00022 21.0 0.5 0.00047 20.0 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM19153.1 - 0.0014 18.4 0.5 0.0029 17.4 0.5 1.5 1 0 0 1 1 1 1 F-box domain DUF1769 PF08588.10 GAM19153.1 - 0.0077 16.4 5.3 22 5.4 0.1 5.3 3 1 3 6 6 6 1 Protein of unknown function (DUF1769) F-box_4 PF15966.5 GAM19153.1 - 0.094 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 F-box ARL6IP6 PF15062.6 GAM19153.1 - 1.2 9.3 3.6 3.7 7.7 0.0 3.2 2 1 2 4 4 4 0 Haemopoietic lineage transmembrane helix adh_short PF00106.25 GAM19154.1 - 2.6e-46 157.5 0.0 3.2e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM19154.1 - 3.2e-30 105.4 0.0 4e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM19154.1 - 5.4e-07 29.7 0.2 2.6e-06 27.5 0.2 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAM19154.1 - 0.011 15.7 0.0 0.2 11.5 0.0 2.3 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 GAM19154.1 - 0.059 12.8 0.0 0.65 9.4 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAM19154.1 - 0.11 11.9 0.0 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain tRNA-synt_1c PF00749.21 GAM19155.1 - 1.2e-97 326.6 0.6 1.7e-97 326.2 0.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAM19155.1 - 1.5e-33 116.1 0.2 7.9e-33 113.8 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 GAM19155.1 - 0.0031 17.7 0.1 0.0085 16.3 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM19155.1 - 0.012 15.8 2.6 0.013 15.7 0.1 2.4 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain DIT1_PvcA PF05141.12 GAM19155.1 - 0.044 13.2 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF87 PF01935.17 GAM19155.1 - 0.27 11.3 1.3 0.54 10.3 1.3 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain RcbX PF02341.15 GAM19155.1 - 0.64 10.3 4.0 0.7 10.2 0.6 2.8 3 1 1 4 4 4 0 RbcX protein Ufm1 PF03671.14 GAM19156.1 - 7.1e-42 141.4 0.1 7.9e-42 141.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein zf-RING_9 PF13901.6 GAM19157.1 - 2.1e-54 184.7 17.5 2.1e-54 184.7 17.5 2.3 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon RUN PF02759.19 GAM19157.1 - 7.7e-27 93.9 2.7 1.6e-19 70.2 0.0 3.3 2 1 0 2 2 2 2 RUN domain Prok-RING_1 PF14446.6 GAM19157.1 - 0.2 11.6 11.4 1.3 9.0 7.5 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 GAM19157.1 - 0.31 11.2 13.6 0.53 10.4 0.1 4.7 4 1 1 5 5 5 0 Zinc ribbon domain ANAPC_CDC26 PF10471.9 GAM19157.1 - 0.53 11.1 14.5 0.044 14.6 4.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DUF678 PF05077.12 GAM19157.1 - 2.8 8.1 8.9 24 5.1 2.6 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF678) Zn_Tnp_IS1595 PF12760.7 GAM19157.1 - 3.2 7.8 15.2 0.54 10.3 3.9 3.2 3 1 0 3 3 3 0 Transposase zinc-ribbon domain SUIM_assoc PF16619.5 GAM19157.1 - 4.4 7.4 15.7 0.13 12.3 6.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DNA_pol_B PF00136.21 GAM19158.1 - 2.1e-139 465.2 0.1 3.2e-139 464.6 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAM19158.1 - 6.4e-82 275.4 0.3 6.4e-82 275.4 0.3 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GAM19158.1 - 1.9e-15 57.1 15.1 3.8e-15 56.1 15.1 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta SASRP1 PF15160.6 GAM19158.1 - 0.018 14.8 0.9 0.39 10.4 0.2 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 DNA_pol_B_2 PF03175.13 GAM19158.1 - 0.02 13.8 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 GAM19158.1 - 0.03 14.3 0.2 0.12 12.3 0.2 2.0 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 GAM19158.1 - 0.045 13.4 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Ribosomal_60s PF00428.19 GAM19158.1 - 2.3 8.9 5.9 6 7.5 5.9 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein BUD22 PF09073.10 GAM19158.1 - 3.8 6.8 8.6 7.1 5.9 8.6 1.4 1 0 0 1 1 1 0 BUD22 UQ_con PF00179.26 GAM19159.1 - 4.9e-30 104.0 0.0 6.8e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.12 GAM19159.1 - 0.15 10.9 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) DUF349 PF03993.12 GAM19160.1 - 0.013 15.8 17.6 0.021 15.1 17.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) I_LWEQ PF01608.17 GAM19160.1 - 0.019 15.2 17.9 0.024 14.9 17.9 1.1 1 0 0 1 1 1 0 I/LWEQ domain DUF1917 PF08939.10 GAM19160.1 - 0.037 13.9 7.2 0.044 13.7 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) CreA PF05981.12 GAM19160.1 - 0.073 13.0 1.2 0.094 12.7 1.2 1.1 1 0 0 1 1 1 0 CreA protein Spc7 PF08317.11 GAM19160.1 - 0.077 11.9 20.8 0.091 11.6 20.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Uds1 PF15456.6 GAM19160.1 - 0.11 12.7 15.4 0.13 12.4 15.4 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Atg14 PF10186.9 GAM19160.1 - 0.18 10.8 18.2 0.22 10.5 18.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Band_3_cyto PF07565.13 GAM19160.1 - 0.21 11.3 11.3 0.23 11.3 11.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Phage_GPO PF05929.11 GAM19160.1 - 0.26 10.9 14.3 0.3 10.7 14.3 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.10 GAM19160.1 - 0.28 11.4 19.9 0.44 10.7 19.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tweety PF04906.13 GAM19160.1 - 0.32 9.6 9.5 0.36 9.4 9.5 1.1 1 0 0 1 1 1 0 Tweety DUF3347 PF11827.8 GAM19160.1 - 0.41 10.8 8.6 0.46 10.6 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Mod_r PF07200.13 GAM19160.1 - 0.65 10.1 24.2 0.94 9.6 24.2 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 GAM19160.1 - 0.67 10.0 13.4 0.89 9.6 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 GAM19160.1 - 1 8.9 20.3 1.1 8.7 20.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit YABBY PF04690.13 GAM19160.1 - 1.5 9.4 9.3 1.8 9.1 9.3 1.0 1 0 0 1 1 1 0 YABBY protein GBP_C PF02841.14 GAM19160.1 - 1.8 7.9 20.4 2.5 7.4 20.4 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain FemAB PF02388.16 GAM19160.1 - 2 7.2 13.4 2.2 7.0 13.4 1.1 1 0 0 1 1 1 0 FemAB family V_ATPase_I PF01496.19 GAM19160.1 - 2.8 5.8 14.8 2.9 5.7 14.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HemX PF04375.14 GAM19160.1 - 3.4 6.9 28.2 4 6.6 28.2 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase ZYG-11_interact PF05884.12 GAM19160.1 - 4.2 6.7 12.4 4.6 6.6 12.4 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 DDE_Tnp_IS66 PF03050.14 GAM19160.1 - 4.5 6.7 12.8 5.4 6.4 12.8 1.0 1 0 0 1 1 1 0 Transposase IS66 family SpecificRecomb PF10136.9 GAM19160.1 - 6 5.0 10.3 6.3 5.0 10.3 1.0 1 0 0 1 1 1 0 Site-specific recombinase Cob_adeno_trans PF01923.18 GAM19160.1 - 6.5 6.9 11.8 11 6.1 11.8 1.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase TMPIT PF07851.13 GAM19160.1 - 7.1 5.8 14.4 8 5.6 14.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein TFIIA PF03153.13 GAM19160.1 - 7.4 6.5 29.4 7.9 6.4 29.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HAUS6_N PF14661.6 GAM19160.1 - 7.7 6.0 16.6 8.9 5.8 16.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus UPF0242 PF06785.11 GAM19160.1 - 8.3 6.5 30.0 10 6.2 30.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LCIB_C_CA PF18599.1 GAM19160.1 - 8.5 5.6 9.1 9.9 5.4 9.1 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases 5_nucleotid PF05761.14 GAM19160.1 - 9.3 5.0 14.1 10 4.9 14.1 1.0 1 0 0 1 1 1 0 5' nucleotidase family Abhydrolase_1 PF00561.20 GAM19161.1 - 3.3e-23 82.6 6.6 2.8e-22 79.6 0.1 3.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM19161.1 - 1.3e-19 71.7 0.4 1.7e-19 71.3 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM19161.1 - 1.2e-13 50.9 0.0 2.8e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 GAM19161.1 - 0.00092 18.0 0.0 0.0019 17.0 0.0 1.4 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 GAM19161.1 - 0.0077 15.9 0.2 0.023 14.3 0.0 1.9 2 0 0 2 2 2 1 Putative esterase Ndc1_Nup PF09531.10 GAM19161.1 - 0.026 13.2 0.1 0.026 13.2 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Abhydrolase_5 PF12695.7 GAM19161.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family TFIIA PF03153.13 GAM19161.1 - 0.13 12.2 13.9 0.23 11.4 13.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 GAM19161.1 - 0.16 12.6 11.9 0.42 11.2 11.9 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 GAM19161.1 - 0.39 9.4 4.4 0.58 8.9 4.4 1.2 1 0 0 1 1 1 0 Presenilin LIDHydrolase PF10230.9 GAM19161.1 - 0.41 10.1 0.0 0.41 10.1 0.0 2.4 4 0 0 4 4 4 0 Lipid-droplet associated hydrolase Tho2 PF11262.8 GAM19161.1 - 1.3 8.1 7.5 2.4 7.3 7.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GATA PF00320.27 GAM19162.1 - 8.4e-17 60.5 5.5 1.9e-16 59.4 5.5 1.6 1 0 0 1 1 1 1 GATA zinc finger SUIM_assoc PF16619.5 GAM19162.1 - 0.011 15.8 5.2 0.011 15.8 5.2 5.1 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 PBP1_TM PF14812.6 GAM19162.1 - 1.4 9.3 12.7 0.12 12.7 6.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Macro PF01661.21 GAM19164.1 - 9.7e-28 96.6 0.1 2.5e-27 95.3 0.1 1.8 1 0 0 1 1 1 1 Macro domain PARP PF00644.20 GAM19164.1 - 1.2e-18 67.4 3.0 8.3e-18 64.7 3.0 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 GAM19164.1 - 3.8e-08 33.8 1.8 3.8e-08 33.8 1.8 3.1 4 0 0 4 4 4 1 WWE domain Lin0512_fam PF09585.10 GAM19164.1 - 0.012 15.7 0.1 0.18 11.9 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical protein (Lin0512_fam) Ank_2 PF12796.7 GAM19166.1 - 0.00068 20.2 0.5 4.5 7.9 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM19167.1 - 0.06 13.9 0.9 41 5.2 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 GAM19168.1 - 1.9e-07 31.6 16.7 0.49 11.0 0.0 8.5 8 2 3 11 11 11 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM19168.1 - 0.00022 21.5 4.6 8.6 6.8 0.0 8.1 7 2 1 8 8 8 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM19168.1 - 0.00041 20.9 7.7 2.3 8.9 0.1 7.6 7 2 0 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19168.1 - 7.1 7.6 28.5 2.6e+02 2.8 0.0 13.0 17 0 0 17 17 17 0 Ankyrin repeat Alpha_kinase PF02816.18 GAM19169.1 - 8.7e-59 198.7 0.1 8.7e-59 198.7 0.1 2.7 3 1 1 4 4 4 1 Alpha-kinase family WD40 PF00400.32 GAM19169.1 - 4.9e-28 96.8 23.9 5.6e-05 23.8 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 GAM19169.1 - 6.2e-06 25.8 3.4 0.061 12.6 0.1 3.0 1 1 2 3 3 3 3 WD40-like domain ANAPC4_WD40 PF12894.7 GAM19169.1 - 7e-05 23.1 1.6 0.19 12.0 0.1 4.1 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM19169.1 - 0.00013 20.8 8.3 0.17 10.5 0.0 4.8 2 2 2 5 5 5 3 Nucleoporin Nup120/160 PQQ_3 PF13570.6 GAM19169.1 - 0.031 14.8 0.0 4.3 7.9 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Baculo_PEP_C PF04513.12 GAM19169.1 - 2.5 8.1 24.0 0.016 15.2 3.3 4.1 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 GAM19169.1 - 3.7 7.4 48.7 3.8 7.3 12.3 3.4 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain Peptidase_S46 PF10459.9 GAM19169.1 - 4.5 5.8 29.4 1.6 7.2 7.4 2.2 2 0 0 2 2 2 0 Peptidase S46 RabGAP-TBC PF00566.18 GAM19170.1 - 3.5e-50 170.6 0.7 8.3e-50 169.4 0.7 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 GAM19170.1 - 1.7e-17 63.7 0.7 5.6e-11 42.9 0.6 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAM19170.1 - 1.3e-14 53.8 0.1 0.00022 21.5 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 GAM19170.1 - 5.9e-13 47.7 0.0 0.0029 18.0 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 GAM19170.1 - 6.2e-12 45.8 0.2 0.00021 21.8 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM19170.1 - 3.3e-08 33.7 0.9 0.21 11.9 0.2 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SHOCT PF09851.9 GAM19171.1 - 0.00065 19.4 0.2 0.00065 19.4 0.2 2.7 3 0 0 3 3 3 1 Short C-terminal domain Pam16 PF03656.13 GAM19171.1 - 0.14 12.1 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 Pam16 TIG PF01833.24 GAM19172.1 - 5.7e-06 26.3 38.8 0.0045 17.0 2.5 6.4 5 1 0 5 5 5 4 IPT/TIG domain EGF_2 PF07974.13 GAM19172.1 - 0.015 15.6 15.0 0.037 14.4 15.0 1.7 1 0 0 1 1 1 0 EGF-like domain EB PF01683.18 GAM19172.1 - 0.75 10.1 8.3 1.8 8.9 8.3 1.6 1 0 0 1 1 1 0 EB module SdrD_B PF17210.3 GAM19173.1 - 2.4e-138 452.8 89.2 8.4e-12 45.3 0.2 15.2 15 0 0 15 15 15 15 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM19173.1 - 8e-69 227.9 27.2 1.1e-07 32.0 0.1 14.7 15 0 0 15 15 14 14 Carboxypeptidase regulatory-like domain SpaA PF17802.1 GAM19173.1 - 1.1e-48 163.5 54.0 1.7e-05 25.0 0.3 15.5 15 0 0 15 15 15 13 Prealbumin-like fold domain bMG3 PF11974.8 GAM19173.1 - 1.5e-29 102.0 0.0 0.08 13.0 0.0 13.6 13 1 1 14 14 14 5 Bacterial alpha-2-macroglobulin MG3 domain CarbopepD_reg_2 PF13715.6 GAM19173.1 - 5.5e-24 84.0 29.1 0.13 12.2 0.1 14.3 14 0 0 14 14 14 8 CarboxypepD_reg-like domain DUF2012 PF09430.10 GAM19173.1 - 1.4e-23 83.4 0.0 0.00063 19.9 0.0 12.5 14 0 0 14 14 14 3 Protein of unknown function (DUF2012) FlgD_ig PF13860.6 GAM19173.1 - 4.4e-19 68.1 15.6 2.6 8.0 0.0 15.6 16 1 0 16 16 15 4 FlgD Ig-like domain Y_Y_Y PF07495.13 GAM19173.1 - 3.8e-10 39.6 24.4 1.8 8.6 0.0 12.9 14 0 0 14 14 14 2 Y_Y_Y domain DUF4019 PF13211.6 GAM19173.1 - 2.5e-08 34.2 0.1 6.5 7.2 0.0 8.1 9 0 0 9 9 8 1 Protein of unknown function (DUF4019) DUF2141 PF09912.9 GAM19173.1 - 6.1e-08 32.6 11.2 5.1 7.1 0.2 12.1 15 1 1 16 16 16 1 Uncharacterized protein conserved in bacteria (DUF2141) DUF2322 PF10084.9 GAM19173.1 - 6.5e-07 29.3 3.1 25 5.0 0.0 8.1 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2322) DUF5119 PF17145.4 GAM19173.1 - 2.5e-06 27.6 15.5 6.4 6.7 0.1 7.7 9 0 0 9 9 9 2 Domain of unknown function (DUF5119) EMP24_GP25L PF01105.24 GAM19173.1 - 0.0002 21.4 8.7 88 3.0 0.0 9.9 10 3 2 13 13 13 0 emp24/gp25L/p24 family/GOLD DUF2846 PF11008.8 GAM19173.1 - 0.00025 21.0 2.5 54 3.9 0.0 8.9 11 2 1 12 12 12 0 Protein of unknown function (DUF2846) RHS PF03527.14 GAM19173.1 - 0.0067 16.2 9.5 44 3.9 0.0 8.2 10 0 0 10 10 10 0 RHS protein fn3_3 PF14686.6 GAM19173.1 - 0.015 15.1 23.5 25 4.8 0.0 11.5 14 0 0 14 14 13 0 Polysaccharide lyase family 4, domain II CDC24_OB3 PF17244.2 GAM19173.1 - 0.029 14.1 0.0 12 5.5 0.0 4.7 5 0 0 5 5 5 0 Cell division control protein 24, OB domain 3 DIPSY PF11763.8 GAM19173.1 - 7.2 6.8 12.2 9.7 6.4 0.2 5.8 7 0 0 7 7 6 0 Cell-wall adhesin ligand-binding C-terminal NIF PF03031.18 GAM19175.1 - 1.7e-57 193.5 0.3 2.5e-57 193.0 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 GAM19175.1 - 0.064 13.7 0.1 0.64 10.4 0.0 2.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Xpo1 PF08389.12 GAM19177.1 - 2.5e-17 63.3 0.9 2.5e-17 63.3 0.9 6.9 6 1 1 7 7 7 1 Exportin 1-like protein CRM1_repeat PF18777.1 GAM19177.1 - 0.0019 17.6 2.4 0.64 9.6 0.1 3.7 3 0 0 3 3 3 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 GAM19177.1 - 0.0027 17.6 0.4 0.0027 17.6 0.4 3.1 4 0 0 4 4 4 1 Importin-beta N-terminal domain DUF1722 PF08349.11 GAM19177.1 - 0.0073 16.6 0.7 0.0073 16.6 0.7 4.7 4 0 0 4 4 4 1 Protein of unknown function (DUF1722) TFCD_C PF12612.8 GAM19177.1 - 0.09 12.6 1.4 0.26 11.1 0.1 2.5 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal DUF4004 PF13171.6 GAM19177.1 - 0.17 12.1 0.0 0.17 12.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4004) ArfGap PF01412.18 GAM19177.1 - 0.29 11.2 0.0 0.29 11.2 0.0 2.7 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Secretin_N_2 PF07655.13 GAM19177.1 - 0.55 10.8 20.9 1.7 9.2 20.9 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain Methyltransf_16 PF10294.9 GAM19178.1 - 6.7e-22 78.0 0.4 3.1e-12 46.6 0.0 2.2 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 GAM19178.1 - 7.1e-07 29.2 0.0 9.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM19178.1 - 0.0023 17.8 0.4 0.0058 16.4 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM19178.1 - 0.0089 16.8 0.1 0.034 14.9 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 GAM19178.1 - 0.0096 15.3 0.0 0.056 12.8 0.0 2.0 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 GAM19178.1 - 0.049 14.3 0.1 3.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAM19178.1 - 0.057 14.1 0.0 0.76 10.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain OGG_N PF07934.12 GAM19179.1 - 5e-24 84.7 1.1 5e-24 84.7 1.1 1.8 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 GAM19179.1 - 9.8e-10 38.9 0.0 1.7e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RXT2_N PF08595.11 GAM19179.1 - 0.0013 18.8 1.6 0.0028 17.7 1.6 1.5 1 0 0 1 1 1 1 RXT2-like, N-terminal Roughex PF06020.11 GAM19179.1 - 0.0029 16.8 0.3 0.0048 16.1 0.3 1.5 1 0 0 1 1 1 1 Drosophila roughex protein HHH PF00633.23 GAM19179.1 - 0.024 14.5 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif PBP1_TM PF14812.6 GAM19179.1 - 0.25 11.7 11.9 0.5 10.8 11.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Trypan_PARP PF05887.11 GAM19179.1 - 0.28 11.2 4.0 0.43 10.6 4.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.12 GAM19179.1 - 0.29 10.4 7.8 0.53 9.5 7.8 1.3 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GAM19179.1 - 0.58 9.8 7.2 1.1 9.0 7.2 1.3 1 0 0 1 1 1 0 FAM176 family AIM3 PF17096.5 GAM19179.1 - 0.92 10.5 7.7 2 9.4 7.7 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 CENP-B_dimeris PF09026.10 GAM19179.1 - 5 7.6 10.2 10 6.6 10.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LapA_dom PF06305.11 GAM19180.1 - 0.04 13.7 1.2 0.084 12.7 1.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Adeno_E3_CR2 PF02439.15 GAM19180.1 - 0.055 13.2 6.3 0.1 12.4 6.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 GAM19180.1 - 0.075 13.0 0.8 0.1 12.5 0.8 1.2 1 0 0 1 1 1 0 Protocadherin SieB PF14163.6 GAM19180.1 - 0.095 12.2 1.0 0.14 11.7 1.0 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B Insulin_TMD PF17870.1 GAM19180.1 - 0.21 11.7 2.1 0.38 10.8 2.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 GAM19180.1 - 0.24 12.3 3.5 0.45 11.4 3.5 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PRIMA1 PF16101.5 GAM19180.1 - 3.3 7.8 5.3 3.5 7.7 4.6 1.4 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 Usp PF00582.26 GAM19182.1 - 1.1e-17 64.9 0.0 1.4e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family CoA_binding_3 PF13727.6 GAM19182.1 - 0.065 13.2 0.1 0.082 12.9 0.1 1.1 1 0 0 1 1 1 0 CoA-binding domain RRM_1 PF00076.22 GAM19183.1 - 1.5e-20 72.8 0.1 2.4e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 GAM19183.1 - 2.3e-06 28.2 0.2 2.3e-06 28.2 0.2 2.2 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_occluded PF16842.5 GAM19183.1 - 0.0032 17.3 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GAM19183.1 - 0.0061 16.5 0.1 0.0097 15.9 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif XS PF03468.14 GAM19183.1 - 0.089 13.1 0.5 0.26 11.6 0.1 1.9 1 1 1 2 2 2 0 XS domain PHM7_cyt PF14703.6 GAM19183.1 - 0.14 12.4 0.7 1.7 8.8 0.7 2.2 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RL PF17797.1 GAM19183.1 - 0.19 11.7 0.2 0.45 10.5 0.2 1.5 1 0 0 1 1 1 0 RL domain MFS_1 PF07690.16 GAM19184.1 - 7e-24 84.4 48.6 4.8e-22 78.4 37.7 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM19184.1 - 0.00021 20.3 5.6 0.00021 20.3 5.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Ank_2 PF12796.7 GAM19185.1 - 0.041 14.5 0.2 2.1 9.0 0.0 3.3 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) RICTOR_V PF14668.6 GAM19185.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Sec1 PF00995.23 GAM19187.1 - 1.1e-119 401.4 6.6 1.2e-119 401.2 6.6 1.0 1 0 0 1 1 1 1 Sec1 family T4SS PF07996.11 GAM19187.1 - 0.084 13.3 3.0 0.23 11.8 1.9 2.1 2 0 0 2 2 2 0 Type IV secretion system proteins Fcf1 PF04900.12 GAM19189.1 - 4.4e-35 120.0 2.7 8.7e-35 119.1 2.7 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 GAM19189.1 - 9.9e-12 45.2 0.0 1.5e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Peptidase_M20 PF01546.28 GAM19190.1 - 1.2e-33 116.5 0.0 1.7e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM19190.1 - 3.9e-08 33.2 0.0 8.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Ras PF00071.22 GAM19191.1 - 1.4e-60 203.5 0.7 2.5e-60 202.8 0.7 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM19191.1 - 6.4e-35 120.0 0.8 1.2e-34 119.0 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM19191.1 - 1.6e-13 50.5 0.2 2.5e-13 49.9 0.2 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM19191.1 - 7.1e-08 32.5 0.1 1.5e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM19191.1 - 1.7e-06 28.1 0.4 0.0081 16.1 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAM19191.1 - 1.6e-05 24.6 1.7 6e-05 22.7 1.7 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAM19191.1 - 5.9e-05 22.5 0.5 7.7e-05 22.2 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM19191.1 - 0.00013 21.4 0.1 0.00053 19.5 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 GAM19191.1 - 0.00048 20.6 0.1 0.001 19.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM19191.1 - 0.0027 18.0 0.3 0.021 15.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 GAM19191.1 - 0.014 15.2 0.2 0.031 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 GAM19191.1 - 0.015 14.7 0.2 0.21 11.0 0.0 2.2 2 1 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 GAM19191.1 - 0.017 14.6 0.2 0.13 11.8 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B KAP_NTPase PF07693.14 GAM19191.1 - 0.033 13.4 0.0 0.063 12.5 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.27 GAM19191.1 - 0.039 14.5 0.9 0.078 13.5 0.9 1.8 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 GAM19191.1 - 0.046 13.5 0.1 0.21 11.3 0.0 2.1 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.23 GAM19191.1 - 0.056 12.5 0.0 0.16 11.0 0.0 1.7 1 1 0 1 1 1 0 MCM P-loop domain AAA_14 PF13173.6 GAM19191.1 - 0.066 13.3 0.2 0.22 11.6 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM19191.1 - 0.075 12.5 0.2 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_21 PF13304.6 GAM19191.1 - 0.19 11.5 1.3 0.32 10.8 0.5 1.7 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Vps26 PF03643.15 GAM19192.1 - 5.9e-128 425.6 5.2 6.8e-128 425.4 5.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 GAM19192.1 - 0.0016 18.5 0.5 0.62 10.1 0.1 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 GAM19192.1 - 0.038 13.2 0.3 17 4.5 0.0 3.0 3 0 0 3 3 3 0 Rgp1 DUF3382 PF11862.8 GAM19193.1 - 1.7 9.0 7.2 0.1 12.9 1.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) Ceramidase PF05875.12 GAM19195.1 - 6.3e-55 186.4 11.1 8.2e-55 186.1 11.1 1.1 1 0 0 1 1 1 1 Ceramidase YidD PF01809.18 GAM19195.1 - 0.093 12.6 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Putative membrane protein insertion efficiency factor Peptidase_M76 PF09768.9 GAM19196.1 - 6.2e-48 162.8 1.2 6.9e-48 162.7 1.2 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 GAM19196.1 - 0.0074 16.1 0.2 0.012 15.4 0.2 1.4 1 0 0 1 1 1 1 SprT-like family Tox-MPTase2 PF15638.6 GAM19196.1 - 0.085 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase toxin 2 RNR_Alpha PF17975.1 GAM19197.1 - 6.4e-42 142.2 0.4 2e-41 140.5 0.4 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 GAM19197.1 - 4e-05 22.4 0.0 0.054 12.0 0.0 3.1 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain Aminotran_3 PF00202.21 GAM19198.1 - 5.3e-116 387.6 0.0 6.2e-116 387.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Ribosomal_L23eN PF03939.13 GAM19199.1 - 8.1e-16 58.0 11.2 1.7e-15 56.9 11.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 GAM19199.1 - 1.1e-13 51.4 3.1 1.1e-13 51.4 3.1 2.6 2 2 0 2 2 2 1 Ribosomal protein L23 FA_desaturase PF00487.24 GAM19200.1 - 0.19 11.5 3.2 0.23 11.3 3.2 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF4191 PF13829.6 GAM19200.1 - 4.1 6.7 4.6 1.2 8.4 1.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) P2X_receptor PF00864.19 GAM19201.1 - 3.6e-22 78.9 0.4 5.9e-11 42.1 1.1 2.6 2 1 1 3 3 3 2 ATP P2X receptor Ribosomal_L32e PF01655.18 GAM19203.1 - 8.8e-46 154.8 0.1 1e-45 154.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 zf-MYND PF01753.18 GAM19204.1 - 5.3e-11 42.4 5.2 1.2e-10 41.3 5.2 1.6 1 0 0 1 1 1 1 MYND finger RhoGAP PF00620.27 GAM19206.1 - 3.6e-34 117.8 0.0 5.5e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Nod1 PF17114.5 GAM19206.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 SOG2 PF10428.9 GAM19206.1 - 1.7 7.8 10.4 2.1 7.4 10.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GST_C_3 PF14497.6 GAM19207.1 - 1.1e-15 57.7 0.1 1.7e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM19207.1 - 3.1e-13 49.9 0.0 1.4e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM19207.1 - 1.9e-06 28.0 0.1 3e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM19207.1 - 8.2e-05 22.5 0.1 0.00014 21.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM19207.1 - 0.00035 20.9 0.0 0.00062 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAM19207.1 - 0.0082 15.9 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1972 PF09314.11 GAM19207.1 - 0.0086 15.7 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1972) Rap_GAP PF02145.15 GAM19208.1 - 2.8e-57 193.3 0.2 7.8e-57 191.8 0.2 1.8 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.8 GAM19208.1 - 8e-46 156.9 9.5 8e-46 156.9 9.5 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) Tuberin PF03542.16 GAM19208.1 - 2.7e-16 59.6 0.9 2.7e-16 59.6 0.9 3.9 3 1 0 3 3 3 2 Tuberin Cnd1 PF12717.7 GAM19208.1 - 0.026 14.6 0.9 1.3 9.1 0.2 3.5 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 GAM19208.1 - 0.034 14.2 0.0 0.19 11.8 0.0 2.4 1 0 0 1 1 1 0 V-ATPase subunit H DUF2142 PF09913.9 GAM19209.1 - 0.26 10.1 11.9 0.091 11.6 7.8 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2142) Oxidored_q2 PF00420.24 GAM19209.1 - 0.8 9.4 12.8 2.6 7.7 1.1 3.2 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L LMF1 PF06762.14 GAM19209.1 - 1.3 8.1 5.7 1.6 7.7 5.7 1.1 1 0 0 1 1 1 0 Lipase maturation factor Phage_holin_1 PF04531.13 GAM19209.1 - 5.1 7.7 7.6 4.1 8.0 3.7 2.4 2 0 0 2 2 2 0 Bacteriophage holin SK_channel PF03530.14 GAM19209.1 - 6.5 6.8 16.9 7 6.7 8.9 2.7 2 2 0 2 2 2 0 Calcium-activated SK potassium channel SnoaL_2 PF12680.7 GAM19210.1 - 0.0017 19.0 0.0 0.0021 18.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF3271 PF11675.8 GAM19210.1 - 0.0017 17.7 2.9 0.0019 17.5 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3271) SnoaL PF07366.12 GAM19210.1 - 0.013 15.3 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Imm-NTF2 PF15655.6 GAM19210.1 - 0.027 14.7 1.5 0.034 14.4 1.5 1.1 1 0 0 1 1 1 0 NTF2 fold immunity protein Brix PF04427.18 GAM19211.1 - 3.3e-35 122.0 0.3 5.6e-35 121.2 0.3 1.4 1 0 0 1 1 1 1 Brix domain DUF3439 PF11921.8 GAM19211.1 - 0.14 12.1 5.4 0.21 11.6 4.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Remorin_N PF03766.13 GAM19211.1 - 0.3 11.2 1.0 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 Remorin, N-terminal region Cpn10 PF00166.21 GAM19212.1 - 1e-20 73.6 0.1 1.1e-20 73.4 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit LSM PF01423.22 GAM19213.1 - 5.2e-14 51.7 0.5 6.5e-14 51.4 0.5 1.1 1 0 0 1 1 1 1 LSM domain MKT1_C PF12246.8 GAM19214.1 - 1.6e-38 132.3 0.2 3.8e-38 131.1 0.2 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 GAM19214.1 - 5.7e-22 77.9 0.0 3.6e-21 75.3 0.0 2.4 2 1 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 GAM19214.1 - 0.015 15.7 0.0 0.042 14.2 0.0 1.9 1 0 0 1 1 1 0 XPG I-region DUF1897 PF09005.10 GAM19214.1 - 0.17 11.4 1.8 0.41 10.2 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) GMC_oxred_N PF00732.19 GAM19215.1 - 1.1e-42 146.5 0.0 1.7e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM19215.1 - 5.1e-24 85.4 1.4 8.9e-24 84.7 1.4 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAM19215.1 - 0.00033 20.8 0.4 0.0025 18.0 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM19215.1 - 0.00042 19.7 0.5 0.0014 17.9 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM19215.1 - 0.0014 17.4 0.1 0.002 16.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 GAM19215.1 - 0.0029 17.3 0.1 0.006 16.2 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 GAM19215.1 - 0.0044 16.7 0.9 0.011 15.4 0.9 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM19215.1 - 0.0089 15.1 4.0 0.017 14.2 4.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 GAM19215.1 - 0.0096 15.0 0.5 0.015 14.4 0.5 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 GAM19215.1 - 0.038 13.1 0.9 0.054 12.6 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A QRPTase_C PF01729.19 GAM19215.1 - 0.15 11.9 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain FAD_binding_3 PF01494.19 GAM19215.1 - 0.16 11.2 1.8 0.26 10.5 1.8 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 GAM19215.1 - 0.17 12.1 3.5 0.084 13.1 0.7 1.9 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 GAM19215.1 - 0.22 10.7 1.5 0.7 9.1 1.5 1.8 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 GAM19215.1 - 0.25 10.6 1.1 0.43 9.9 1.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 GAM19215.1 - 0.81 8.5 2.1 3.8 6.3 3.2 1.5 2 0 0 2 2 2 0 Tryptophan halogenase ABC_tran PF00005.27 GAM19216.1 - 2e-25 89.9 0.0 3e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GAM19216.1 - 9.5e-11 41.5 0.7 1.4e-10 41.0 0.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 GAM19216.1 - 9.1e-06 25.7 0.1 0.022 14.6 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 GAM19216.1 - 3.6e-05 24.3 0.0 8.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAM19216.1 - 6e-05 22.7 0.2 0.00015 21.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM19216.1 - 0.00014 21.9 0.4 0.00029 20.8 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 GAM19216.1 - 0.0004 20.8 0.0 0.0007 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 GAM19216.1 - 0.00046 19.8 0.0 0.00082 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 GAM19216.1 - 0.0019 17.7 0.0 0.041 13.3 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 GAM19216.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 GAM19216.1 - 0.008 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 GAM19216.1 - 0.01 16.0 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAM19216.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 GAM19216.1 - 0.014 15.7 0.0 0.039 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAM19216.1 - 0.025 14.5 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 GAM19216.1 - 0.029 14.6 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 GAM19216.1 - 0.036 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase T2SSE PF00437.20 GAM19216.1 - 0.038 13.0 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.6 GAM19216.1 - 0.039 14.4 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PHO4 PF01384.20 GAM19216.1 - 0.04 13.0 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family AAA_23 PF13476.6 GAM19216.1 - 0.079 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAM19216.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC2_membrane PF01061.24 GAM19217.1 - 5.9e-24 84.6 12.8 5.9e-24 84.6 12.8 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 GAM19217.1 - 0.0042 16.2 17.5 0.0059 15.8 17.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Longin PF13774.6 GAM19218.1 - 6e-23 80.7 1.5 1.1e-22 79.8 1.5 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 GAM19218.1 - 7.7e-14 51.2 0.1 1.6e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Synaptobrevin Imm10 PF15588.6 GAM19218.1 - 0.047 13.8 0.2 0.094 12.8 0.2 1.4 1 0 0 1 1 1 0 Immunity protein 10 SLM4 PF16818.5 GAM19218.1 - 0.057 13.4 0.3 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 Protein SLM4 TPR_1 PF00515.28 GAM19219.1 - 1.5e-15 56.3 2.9 4.7e-05 23.0 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM19219.1 - 8.7e-14 50.5 0.8 0.00044 20.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 GAM19219.1 - 5.6e-08 32.5 16.1 1.5e-07 31.2 16.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.6 GAM19219.1 - 8.3e-08 31.9 2.1 0.0012 18.9 0.0 3.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM19219.1 - 8.7e-07 28.9 1.1 0.0048 17.2 0.2 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat zf-C3HC4 PF00097.25 GAM19219.1 - 9.5e-07 28.6 15.6 2.6e-06 27.2 15.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ANAPC3 PF12895.7 GAM19219.1 - 1.2e-06 28.6 2.6 1.2e-06 28.6 2.6 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 zf-RING_5 PF14634.6 GAM19219.1 - 3.1e-06 27.1 14.9 8e-06 25.7 14.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.6 GAM19219.1 - 3.9e-06 26.4 0.2 0.11 12.2 0.2 3.5 1 1 2 3 3 3 1 TPR repeat zf-C3HC4_3 PF13920.6 GAM19219.1 - 1.9e-05 24.4 11.2 1.9e-05 24.4 11.2 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM19219.1 - 3.3e-05 23.8 10.1 3.3e-05 23.8 10.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger NARP1 PF12569.8 GAM19219.1 - 3.3e-05 23.0 0.2 5e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 zf-RING_2 PF13639.6 GAM19219.1 - 3.4e-05 24.1 15.0 9.5e-05 22.7 15.0 1.8 1 0 0 1 1 1 1 Ring finger domain TPR_12 PF13424.6 GAM19219.1 - 4.6e-05 23.6 2.7 0.0018 18.6 1.1 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 GAM19219.1 - 0.00031 20.8 16.4 0.00064 19.8 16.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAM19219.1 - 0.00088 19.1 7.5 0.0018 18.1 7.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein TPR_16 PF13432.6 GAM19219.1 - 0.0023 18.6 0.0 0.8 10.4 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM19219.1 - 0.0023 18.4 0.0 0.044 14.3 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Prok-RING_4 PF14447.6 GAM19219.1 - 0.0029 17.4 14.8 0.47 10.3 16.1 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 TPR_9 PF13371.6 GAM19219.1 - 0.014 15.5 0.5 0.089 13.0 0.1 2.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM19219.1 - 0.044 13.8 0.4 42 4.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SPX PF03105.19 GAM19219.1 - 0.071 13.0 8.1 0.077 12.9 8.1 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 GAM19219.1 - 0.61 8.6 9.6 0.73 8.3 9.6 1.2 1 0 0 1 1 1 0 Macoilin family Zn-C2H2_12 PF18112.1 GAM19219.1 - 0.68 10.4 8.0 1.2 9.7 2.4 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Presenilin PF01080.17 GAM19219.1 - 0.88 8.3 3.7 1.1 7.9 3.7 1.1 1 0 0 1 1 1 0 Presenilin zf-RING_4 PF14570.6 GAM19219.1 - 1.2 9.0 16.6 0.56 10.0 13.6 2.0 2 1 0 2 2 1 0 RING/Ubox like zinc-binding domain Med3 PF11593.8 GAM19219.1 - 2.2 7.4 12.4 4.2 6.5 12.4 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Baculo_IE-1 PF05290.11 GAM19219.1 - 4.6 7.2 10.4 4.2 7.3 7.0 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Apt1 PF10351.9 GAM19219.1 - 8.3 5.1 11.3 11 4.8 11.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain WWE PF02825.20 GAM19220.1 - 2.2e-10 41.0 0.5 5.2e-10 39.8 0.2 1.9 2 0 0 2 2 2 1 WWE domain PARP PF00644.20 GAM19220.1 - 6.8e-08 32.3 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Vault PF01505.18 GAM19220.1 - 0.0015 18.7 0.7 0.0032 17.6 0.0 2.0 2 0 0 2 2 2 1 Major Vault Protein repeat domain RasGAP PF00616.19 GAM19221.1 - 6.8e-49 166.4 4.3 6.8e-49 166.4 4.3 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAM19221.1 - 1.4e-14 54.4 7.5 1.4e-14 54.4 7.5 2.9 3 0 0 3 3 3 1 RasGAP C-terminus MCM_N PF14551.6 GAM19221.1 - 0.082 13.5 3.2 0.12 13.0 0.5 2.6 2 0 0 2 2 2 0 MCM N-terminal domain DUF4118 PF13493.6 GAM19222.1 - 0.0071 16.1 0.3 0.0071 16.1 0.3 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4118) CitMHS PF03600.16 GAM19222.1 - 1.9 7.6 7.1 0.17 11.0 2.0 1.6 1 1 1 2 2 2 0 Citrate transporter EpsG PF14897.6 GAM19222.1 - 2.8 7.2 31.2 11 5.2 24.1 2.7 1 1 1 2 2 2 0 EpsG family Beta_helix PF13229.6 GAM19223.1 - 6.7e-47 159.3 69.2 7.6e-23 81.1 24.0 3.7 2 1 2 4 4 4 3 Right handed beta helix region NosD PF05048.13 GAM19223.1 - 1.3e-27 96.7 38.1 6.1e-13 48.6 12.5 3.3 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) zf-UBR PF02207.20 GAM19223.1 - 1.7e-08 34.5 12.7 4.5e-08 33.2 12.7 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) F-box-like PF12937.7 GAM19223.1 - 2.7e-07 30.4 1.8 5.5e-07 29.4 1.8 1.5 1 0 0 1 1 1 1 F-box-like Pectate_lyase_3 PF12708.7 GAM19223.1 - 3.2e-06 27.1 27.1 0.062 13.1 12.5 4.0 1 1 1 2 2 2 2 Pectate lyase superfamily protein F-box PF00646.33 GAM19223.1 - 4.8e-06 26.3 2.6 8.7e-06 25.5 2.6 1.5 1 0 0 1 1 1 1 F-box domain zf-C4_ClpX PF06689.13 GAM19223.1 - 9.3 6.2 8.6 1.2 9.1 3.9 2.0 2 0 0 2 2 2 0 ClpX C4-type zinc finger BTB PF00651.31 GAM19224.1 - 2.2e-16 60.0 1.9 1.1e-13 51.4 0.3 2.6 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 GAM19224.1 - 7.5e-12 45.3 1.7 6.8e-09 35.8 0.3 3.3 3 0 0 3 3 3 1 BTB And C-terminal Kelch Sad1_UNC PF07738.13 GAM19224.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 GAM19224.1 - 0.0051 16.9 0.0 0.0095 16.1 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain PWWP PF00855.17 GAM19225.1 - 6.1e-13 49.0 0.6 6.1e-13 49.0 0.6 3.1 3 0 0 3 3 3 1 PWWP domain Acatn PF13000.7 GAM19226.1 - 3.1e-128 428.7 28.2 1.8e-102 343.6 15.2 2.5 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 TMEM220 PF15071.6 GAM19226.1 - 0.65 10.8 6.6 0.32 11.8 1.0 3.0 3 0 0 3 3 3 0 Transmembrane family 220, helix FNIP PF05725.12 GAM19227.1 - 1.1e-60 201.6 18.4 8.7e-13 48.2 0.0 9.3 8 2 0 9 9 9 6 FNIP Repeat LRR_8 PF13855.6 GAM19227.1 - 0.11 12.2 3.2 16 5.4 0.0 4.2 4 0 0 4 4 4 0 Leucine rich repeat UBM PF14377.6 GAM19227.1 - 1.8 8.1 4.6 2.7 7.6 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin binding region ECR1_N PF14382.6 GAM19228.1 - 2.9e-14 52.6 0.1 6.7e-14 51.4 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 GAM19228.1 - 2.4e-12 47.4 9.4 5.8e-12 46.2 0.3 3.0 3 1 1 4 4 4 2 Exosome component EXOSC1/CSL4 CM_1 PF07736.11 GAM19228.1 - 0.00054 20.3 0.0 0.00088 19.7 0.0 1.3 1 0 0 1 1 1 1 Chorismate mutase type I DNA_pol_B_palm PF14792.6 GAM19229.1 - 4.1e-30 104.3 0.8 6.3e-28 97.3 0.1 2.5 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 GAM19229.1 - 2.4e-18 66.0 0.0 9.9e-18 64.1 0.0 2.1 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 GAM19229.1 - 9.3e-15 54.2 0.1 3.8e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda YL1 PF05764.13 GAM19229.1 - 8.4e-07 29.3 20.8 0.00023 21.4 11.6 2.3 2 0 0 2 2 2 2 YL1 nuclear protein HHH_5 PF14520.6 GAM19229.1 - 1.9e-05 25.1 7.4 0.0012 19.4 2.0 2.9 2 1 1 3 3 2 2 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 GAM19229.1 - 0.00051 20.3 0.7 0.0013 19.0 0.0 2.1 2 0 0 2 2 1 1 Nucleotidyltransferase domain HHH_8 PF14716.6 GAM19229.1 - 0.00078 19.8 1.9 0.053 13.9 0.2 3.1 2 1 1 3 3 3 1 Helix-hairpin-helix domain Cwf_Cwc_15 PF04889.12 GAM19229.1 - 0.0042 16.9 10.8 0.0042 16.9 10.8 2.5 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 GAM19229.1 - 0.01 15.8 8.9 0.01 15.8 8.9 2.5 2 0 0 2 2 2 1 Sigma-70, non-essential region HHH_3 PF12836.7 GAM19229.1 - 0.052 13.8 0.4 5.7 7.3 0.1 2.6 1 1 1 2 2 2 0 Helix-hairpin-helix motif Suf PF05843.14 GAM19229.1 - 0.058 13.4 8.7 0.026 14.5 1.8 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF5055 PF16478.5 GAM19229.1 - 0.066 13.5 0.0 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5055) HHH PF00633.23 GAM19229.1 - 0.14 12.1 0.4 11 6.1 0.1 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif LTV PF04180.14 GAM19229.1 - 0.15 11.8 18.5 0.1 12.3 7.9 2.2 2 0 0 2 2 2 0 Low temperature viability protein Nop14 PF04147.12 GAM19229.1 - 0.17 10.1 28.8 0.0038 15.5 12.2 2.2 2 0 0 2 2 2 0 Nop14-like family DUF2052 PF09747.9 GAM19229.1 - 0.44 10.6 25.7 0.05 13.7 12.0 2.6 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Velvet PF11754.8 GAM19229.1 - 0.47 10.4 6.5 5.4 6.9 1.1 2.2 2 0 0 2 2 2 0 Velvet factor Lin-8 PF03353.15 GAM19229.1 - 0.78 9.2 19.7 0.0098 15.5 4.0 2.8 4 0 0 4 4 4 0 Ras-mediated vulval-induction antagonist Raftlin PF15250.6 GAM19229.1 - 0.78 8.4 19.5 0.0075 15.1 4.6 2.1 2 0 0 2 2 2 0 Raftlin Spt5_N PF11942.8 GAM19229.1 - 0.81 10.7 31.4 0.56 11.2 3.5 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal E_Pc_C PF06752.12 GAM19229.1 - 2.1 8.4 15.8 3.7 7.6 4.3 2.2 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Utp14 PF04615.13 GAM19229.1 - 2.3 6.7 27.8 0.033 12.8 7.8 2.8 3 0 0 3 3 3 0 Utp14 protein DAG_kinase_N PF14513.6 GAM19229.1 - 3.2 7.9 11.4 0.8 9.9 1.1 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Neur_chan_memb PF02932.16 GAM19229.1 - 4.7 7.2 10.0 0.71 9.9 1.6 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.6 GAM19229.1 - 5.7 7.4 8.3 5.9 7.4 1.5 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Zip PF02535.22 GAM19229.1 - 5.8 6.0 12.7 0.38 9.9 3.2 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter V_ATPase_I PF01496.19 GAM19229.1 - 6.5 4.5 6.6 1.1 7.0 1.1 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pex14_N PF04695.13 GAM19229.1 - 6.6 7.4 14.6 4.2 8.0 2.8 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rtf2 PF04641.12 GAM19229.1 - 7.8 5.8 21.9 2.1 7.6 8.5 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger Sporozoite_P67 PF05642.11 GAM19229.1 - 7.8 4.4 27.9 2.2 6.3 11.9 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Macoilin PF09726.9 GAM19229.1 - 9.3 4.7 21.1 0.18 10.3 4.6 2.2 2 0 0 2 2 2 0 Macoilin family VCBS PF13517.6 GAM19231.1 - 3.8e-22 78.6 15.3 2.5e-08 34.4 0.4 5.7 4 2 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAM19231.1 - 2.5e-16 59.5 13.6 0.00024 21.2 0.4 6.7 6 0 0 6 6 6 6 FG-GAP repeat BBS2_Mid PF14783.6 GAM19231.1 - 1.6e-09 37.8 0.6 0.44 10.6 0.0 6.1 6 1 1 7 7 7 3 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 GAM19231.1 - 5.1e-08 32.5 2.0 0.02 14.8 0.0 5.2 6 0 0 6 6 6 2 PQQ enzyme repeat PQQ_3 PF13570.6 GAM19231.1 - 2e-07 31.3 10.6 0.0012 19.3 0.2 6.4 7 0 0 7 7 7 2 PQQ-like domain Itfg2 PF15907.5 GAM19231.1 - 2.7e-07 30.0 5.6 0.34 9.9 0.0 5.6 4 1 1 6 6 6 3 Integrin-alpha FG-GAP repeat-containing protein 2 PQQ_2 PF13360.6 GAM19231.1 - 1.4e-05 24.8 0.0 0.00039 20.1 0.0 2.7 2 1 0 2 2 2 1 PQQ-like domain BBS2_C PF14782.6 GAM19231.1 - 0.0014 17.5 0.3 0.91 8.2 0.0 3.8 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, C-terminal OTU PF02338.19 GAM19231.1 - 0.0028 18.1 0.9 0.0062 17.0 0.9 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease BBS1 PF14779.6 GAM19231.1 - 0.0032 17.0 0.5 17 4.8 0.1 4.8 3 1 2 5 5 5 0 Ciliary BBSome complex subunit 1 KMP11 PF03037.16 GAM19231.1 - 0.75 10.6 5.3 1.8 9.4 3.1 2.5 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 SET PF00856.28 GAM19232.1 - 6.1e-16 59.3 0.2 1.2e-15 58.3 0.1 1.6 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 GAM19232.1 - 1.1e-08 35.8 0.2 1.9e-08 35.1 0.2 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Cad PF03596.13 GAM19233.1 - 0.0092 15.9 0.9 0.022 14.7 0.9 1.6 1 0 0 1 1 1 1 Cadmium resistance transporter CTP_transf_like PF01467.26 GAM19234.1 - 6.7e-15 55.5 0.0 1e-14 55.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF2052 PF09747.9 GAM19235.1 - 1 9.4 40.4 0.019 15.1 8.9 3.5 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) EMP24_GP25L PF01105.24 GAM19236.1 - 6.4e-35 120.7 9.2 3.7e-21 75.9 0.6 2.2 1 1 1 2 2 2 2 emp24/gp25L/p24 family/GOLD Claudin_2 PF13903.6 GAM19236.1 - 0.0017 18.2 1.9 0.041 13.6 0.1 2.1 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction DUF308 PF03729.13 GAM19236.1 - 0.0073 16.6 1.6 0.048 14.0 0.1 2.2 2 0 0 2 2 2 1 Short repeat of unknown function (DUF308) Iron_permease PF04120.12 GAM19237.1 - 0.085 12.6 2.5 0.099 12.4 1.9 1.4 1 1 0 1 1 1 0 Low affinity iron permease WD40 PF00400.32 GAM19238.1 - 1.1e-24 86.2 26.4 0.00019 22.1 0.1 10.7 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM19238.1 - 1.3e-15 57.4 1.0 0.0016 18.7 0.0 5.8 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM19238.1 - 5.2e-05 22.1 0.1 0.44 9.1 0.1 3.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 CX9C PF16860.5 GAM19239.1 - 6.2e-05 22.9 6.9 0.032 14.2 2.1 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 GAM19239.1 - 0.026 14.7 6.1 0.078 13.1 2.1 2.9 3 1 1 4 4 4 0 CHCH domain Cmc1 PF08583.10 GAM19239.1 - 0.053 13.5 11.8 1.2 9.3 3.8 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 GAM19239.1 - 1.5 8.6 7.7 4.2 7.2 0.3 2.8 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pkinase PF00069.25 GAM19240.1 - 1.5e-59 201.5 0.0 7.9e-59 199.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19240.1 - 1.1e-24 87.2 0.1 8.9e-17 61.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GAM19240.1 - 0.00083 19.3 0.0 0.0046 16.9 0.0 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAM19240.1 - 0.001 18.5 0.0 0.019 14.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 GAM19240.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SUZ PF12752.7 GAM19240.1 - 1.6 9.5 5.7 15 6.4 3.3 2.8 2 0 0 2 2 2 0 SUZ domain E1-E2_ATPase PF00122.20 GAM19242.1 - 3.5e-37 127.7 2.2 5.4e-37 127.1 0.8 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAM19242.1 - 3.7e-18 65.9 7.1 3.7e-18 65.9 7.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAM19242.1 - 3.6e-15 56.8 0.3 7.3e-15 55.8 0.3 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM19242.1 - 5.7e-12 45.1 0.0 1.2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAM19242.1 - 3.6e-05 23.7 0.0 8.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM19242.1 - 0.0036 17.1 0.1 0.092 12.5 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2768 PF10966.8 GAM19242.1 - 0.013 15.9 0.8 0.053 14.0 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) CorA PF01544.18 GAM19243.1 - 0.004 16.5 17.6 0.0078 15.6 16.1 2.3 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2407_C PF13373.6 GAM19243.1 - 0.03 14.5 0.5 0.63 10.2 0.0 2.7 3 0 0 3 3 3 0 DUF2407 C-terminal domain SUIM_assoc PF16619.5 GAM19243.1 - 1.3 9.2 12.0 8.8 6.5 6.5 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 GAM19244.1 - 3.1e-32 110.1 9.3 8.1e-09 36.0 0.1 7.6 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM19244.1 - 5.1e-13 49.1 0.2 0.0001 22.5 0.0 5.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM19244.1 - 1.5e-05 25.0 1.5 0.046 13.6 0.3 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAM19244.1 - 0.0034 16.8 0.5 0.055 12.8 0.5 2.5 2 1 1 3 3 3 1 WD40-like domain DUF3450 PF11932.8 GAM19244.1 - 0.0041 16.5 7.8 0.0083 15.5 7.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF1387 PF07139.11 GAM19244.1 - 0.01 15.6 8.2 0.01 15.6 8.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) DUF4175 PF13779.6 GAM19244.1 - 0.012 13.6 5.8 0.018 13.0 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FlaC_arch PF05377.11 GAM19244.1 - 0.017 15.5 0.1 0.017 15.5 0.1 2.3 3 0 0 3 3 1 0 Flagella accessory protein C (FlaC) Ge1_WD40 PF16529.5 GAM19244.1 - 0.031 13.2 0.1 0.8 8.6 0.0 3.1 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nnf1 PF03980.14 GAM19244.1 - 0.04 14.3 5.5 0.085 13.3 5.5 1.5 1 0 0 1 1 1 0 Nnf1 DivIC PF04977.15 GAM19244.1 - 0.048 13.4 9.9 0.067 13.0 0.3 2.6 2 0 0 2 2 2 0 Septum formation initiator Frtz PF11768.8 GAM19244.1 - 0.05 11.9 0.0 0.11 10.7 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2203 PF09969.9 GAM19244.1 - 0.23 12.2 1.2 0.61 10.8 1.2 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ATG16 PF08614.11 GAM19244.1 - 0.27 11.4 12.7 0.6 10.3 12.7 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) End3 PF12761.7 GAM19244.1 - 0.38 10.9 10.8 0.061 13.5 6.6 1.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF3597 PF12200.8 GAM19244.1 - 0.4 11.2 3.8 0.95 10.0 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF4407 PF14362.6 GAM19244.1 - 0.51 9.6 4.7 0.83 9.0 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pannexin_like PF12534.8 GAM19244.1 - 0.75 8.8 6.7 1.4 7.9 6.7 1.4 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Cnn_1N PF07989.11 GAM19244.1 - 2 8.6 6.6 9.8 6.4 6.6 2.2 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF5094 PF17015.5 GAM19244.1 - 2.4 8.2 10.1 0.74 9.9 5.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) Adaptin_binding PF10199.9 GAM19244.1 - 2.4 8.8 7.9 12 6.5 6.4 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Prominin PF05478.11 GAM19244.1 - 2.8 5.8 5.3 5 4.9 5.3 1.3 1 0 0 1 1 1 0 Prominin SR-25 PF10500.9 GAM19244.1 - 2.9 7.4 15.8 0.12 11.9 9.6 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Roughex PF06020.11 GAM19244.1 - 6.3 5.8 7.0 13 4.8 7.0 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 GAM19244.1 - 8.9 5.8 19.9 6 6.4 17.7 1.8 2 0 0 2 2 2 0 Spt20 family Abhydrolase_1 PF00561.20 GAM19245.1 - 4.9e-07 29.7 0.0 7.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM19245.1 - 1.5e-05 25.7 0.1 1.8e-05 25.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAM19245.1 - 4.8e-05 22.9 0.0 0.00032 20.2 0.0 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 GAM19245.1 - 0.00031 20.1 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 GAM19245.1 - 0.00034 20.2 0.0 0.00047 19.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF818 PF05677.12 GAM19245.1 - 0.082 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 GAM19245.1 - 0.19 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold APG6 PF04111.12 GAM19246.1 - 1.5e-67 227.0 0.5 3.1e-67 226.0 0.5 1.6 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 GAM19246.1 - 2.5e-19 70.1 8.6 2.5e-19 70.1 8.6 2.6 2 0 0 2 2 2 1 Apg6 coiled-coil region Claudin_3 PF06653.11 GAM19247.1 - 0.13 12.2 7.6 0.045 13.7 3.9 1.9 1 1 1 2 2 2 0 Tight junction protein, Claudin-like TMEMspv1-c74-12 PF11044.8 GAM19247.1 - 0.6 10.1 5.8 2.1 8.4 5.8 1.9 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein GTP_EFTU PF00009.27 GAM19248.1 - 1.5e-54 184.5 0.0 1.9e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM19248.1 - 1.5e-21 76.8 0.1 5.1e-21 75.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAM19248.1 - 1.2e-14 54.4 2.4 2.7e-14 53.3 2.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM19248.1 - 1.4e-05 25.1 0.1 3.3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM19248.1 - 0.1 12.1 0.3 3.9 7.0 0.3 2.8 1 1 0 1 1 1 0 Ferrous iron transport protein B RRN3 PF05327.11 GAM19249.1 - 3.5e-88 296.6 55.7 1.9e-50 172.0 5.6 3.9 3 1 0 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 Spt20 PF12090.8 GAM19249.1 - 0.00065 19.4 22.4 0.0018 18.0 13.9 2.6 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 GAM19249.1 - 0.0014 17.7 7.6 0.0014 17.7 7.6 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 GAM19249.1 - 0.45 11.5 15.2 3.4 8.7 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) YABBY PF04690.13 GAM19249.1 - 8.8 6.9 7.4 44 4.6 0.1 2.5 2 0 0 2 2 2 0 YABBY protein F-box_5 PF18511.1 GAM19250.1 - 0.086 12.4 0.2 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 GAM19250.1 - 0.1 12.5 1.7 0.27 11.2 0.1 2.6 3 0 0 3 3 3 0 F-box-like F-box-like PF12937.7 GAM19251.1 - 0.021 14.7 0.1 0.063 13.2 0.1 1.9 1 0 0 1 1 1 0 F-box-like F-box_5 PF18511.1 GAM19251.1 - 0.038 13.6 0.2 0.15 11.7 0.2 2.0 1 0 0 1 1 1 0 F-box CMV_US PF08001.11 GAM19251.1 - 0.046 13.0 0.1 4.8 6.4 0.1 2.4 2 0 0 2 2 2 0 CMV US RHH_4 PF13467.6 GAM19251.1 - 0.11 12.4 0.0 2.1 8.3 0.0 2.7 1 1 0 1 1 1 0 Ribbon-helix-helix domain PH PF00169.29 GAM19252.1 - 1.3e-10 41.7 0.0 9.8e-10 38.9 0.0 2.7 1 0 0 1 1 1 1 PH domain CENP-F_leu_zip PF10473.9 GAM19252.1 - 0.00033 20.7 20.0 0.00033 20.7 20.0 9.8 1 1 8 9 9 7 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PH_11 PF15413.6 GAM19252.1 - 0.00034 21.0 0.8 0.00034 21.0 0.8 4.1 2 2 1 3 3 3 1 Pleckstrin homology domain APG6_N PF17675.1 GAM19252.1 - 0.00069 20.1 23.0 0.00069 20.1 23.0 9.3 1 1 7 8 8 4 2 Apg6 coiled-coil region GAS PF13851.6 GAM19252.1 - 0.0056 16.0 147.1 0.021 14.2 22.0 8.1 2 2 6 8 8 8 5 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.11 GAM19252.1 - 0.0067 16.3 5.4 0.0067 16.3 5.4 8.4 2 2 5 8 8 6 2 Bacillus haemolytic enterotoxin (HBL) PH_8 PF15409.6 GAM19252.1 - 0.0074 16.5 0.8 0.078 13.3 0.8 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 GAM19252.1 - 0.15 12.2 0.0 0.15 12.2 0.0 3.3 6 0 0 6 6 6 0 PH domain PRANC PF09372.10 GAM19252.1 - 0.59 10.5 4.8 0.54 10.6 0.1 3.4 3 1 0 3 3 3 0 PRANC domain PE PF00934.20 GAM19252.1 - 2 8.8 5.5 2 8.8 0.3 3.6 4 0 0 4 4 4 0 PE family TMEM191C PF15194.6 GAM19252.1 - 2.6 8.3 5.5 4.2 7.6 0.1 3.3 3 0 0 3 3 3 0 TMEM191C family TERB2 PF15101.6 GAM19253.1 - 0.00021 21.4 1.4 0.00021 21.4 1.4 2.2 2 0 0 2 2 2 1 Telomere-associated protein TERB2 BRCT_2 PF16589.5 GAM19253.1 - 0.011 16.1 0.1 0.034 14.6 0.1 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Acetyltransf_1 PF00583.25 GAM19254.1 - 3.7e-09 36.9 0.0 5.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM19254.1 - 5.6e-07 29.5 0.0 8.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM19254.1 - 1.9e-05 25.0 0.0 3.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM19254.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Adaptin_N PF01602.20 GAM19255.1 - 2.2e-114 382.9 17.6 9.2e-114 380.9 17.1 2.0 2 0 0 2 2 2 1 Adaptin N terminal region COP-gamma_platf PF08752.10 GAM19255.1 - 3.9e-56 189.4 0.1 8e-56 188.4 0.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 GAM19255.1 - 1e-29 103.0 0.1 3.3e-29 101.3 0.1 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 GAM19255.1 - 2.7e-18 66.1 1.1 3.8e-08 33.6 0.0 5.4 3 2 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 GAM19255.1 - 1.1e-15 58.1 15.3 8.3e-08 32.4 1.4 4.7 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 GAM19255.1 - 7.7e-07 29.2 0.1 2.2e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.22 GAM19255.1 - 1.5e-05 24.8 4.7 0.51 10.7 0.1 5.9 7 0 0 7 7 6 2 HEAT repeat DUF1241 PF06840.11 GAM19255.1 - 0.0081 15.8 0.1 0.071 12.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) Sec23_helical PF04815.15 GAM19255.1 - 0.017 14.9 0.4 0.25 11.2 0.1 2.9 3 0 0 3 3 3 0 Sec23/Sec24 helical domain Vac14_Fab1_bd PF12755.7 GAM19255.1 - 0.036 14.7 6.2 11 6.7 0.0 4.8 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 GAM19255.1 - 0.56 10.8 3.9 59 4.3 0.1 4.8 4 1 1 5 5 5 0 HEAT-like repeat DUF4745 PF15923.5 GAM19256.1 - 0.092 12.7 1.6 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) PI3K_P85_iSH2 PF16454.5 GAM19256.1 - 0.12 12.0 29.0 3.1 7.4 26.9 3.6 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FAM76 PF16046.5 GAM19256.1 - 0.19 11.1 25.3 0.52 9.6 11.6 2.5 1 1 1 2 2 2 0 FAM76 protein HIP1_clath_bdg PF16515.5 GAM19256.1 - 0.26 11.9 23.2 3.1 8.5 2.3 3.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PKcGMP_CC PF16808.5 GAM19256.1 - 0.59 10.0 17.8 0.17 11.8 1.5 4.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fez1 PF06818.15 GAM19256.1 - 1.4 9.3 30.3 14 6.1 19.8 3.3 2 1 1 3 3 3 0 Fez1 DUF948 PF06103.11 GAM19256.1 - 2.6 8.4 0.0 2.6 8.4 0.0 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 GAM19256.1 - 4 6.7 21.8 38 3.5 21.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 GAM19257.1 - 5.8e-53 179.9 0.1 1.7e-52 178.4 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19257.1 - 7e-32 110.7 0.0 1.3e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM19257.1 - 8.9e-06 24.7 0.1 2.3e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAM19257.1 - 0.029 13.7 0.2 0.59 9.4 0.1 2.6 2 1 1 3 3 3 0 Kinase-like APH PF01636.23 GAM19257.1 - 0.033 14.1 0.0 0.8 9.6 0.0 2.7 2 2 2 4 4 4 0 Phosphotransferase enzyme family FTA2 PF13095.6 GAM19257.1 - 0.036 13.7 0.8 8.4 6.0 0.0 3.1 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SR-25 PF10500.9 GAM19257.1 - 1.8 8.1 9.8 3.1 7.3 9.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FNIP PF05725.12 GAM19258.1 - 6.9e-96 314.2 52.9 9.4e-14 51.3 1.6 11.2 6 2 7 13 13 13 12 FNIP Repeat Glyc_hyd_38C_2 PF18230.1 GAM19258.1 - 0.066 13.3 1.2 11 6.2 0.3 3.0 3 0 0 3 3 3 0 Glycosyl hydrolases family 38 C-terminal sub-domain Peptidase_C1 PF00112.23 GAM19259.1 - 5.7e-59 199.8 0.4 8.6e-59 199.3 0.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM19259.1 - 7.7e-15 55.1 4.6 1.4e-14 54.3 4.6 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Cation_efflux PF01545.21 GAM19260.1 - 1.8e-49 168.2 10.4 2.4e-49 167.8 10.4 1.2 1 0 0 1 1 1 1 Cation efflux family V_ATPase_I PF01496.19 GAM19260.1 - 0.11 10.4 2.3 1 7.2 0.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 GAM19260.1 - 0.47 10.2 2.7 4.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Connexin Zip PF02535.22 GAM19260.1 - 0.55 9.4 39.7 0.026 13.7 7.6 2.6 2 1 1 3 3 3 0 ZIP Zinc transporter Cation_ATPase_C PF00689.21 GAM19260.1 - 1.2 8.8 9.6 0.081 12.6 3.8 1.8 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus SUR7 PF06687.12 GAM19260.1 - 1.8 8.2 7.1 4.7 6.8 0.0 2.6 3 0 0 3 3 3 0 SUR7/PalI family DUF3487 PF11990.8 GAM19261.1 - 8.3 6.3 10.2 9.8 6.1 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) EGF_2 PF07974.13 GAM19262.1 - 0.0019 18.5 18.5 0.03 14.7 1.7 3.1 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 GAM19262.1 - 0.0027 17.8 23.0 0.036 14.2 5.2 2.9 3 0 0 3 3 3 2 Laminin EGF domain Alpha_L_fucos PF01120.17 GAM19263.1 - 8.8e-57 193.1 1.3 2.9e-56 191.4 1.3 1.7 1 1 0 1 1 1 1 Alpha-L-fucosidase DUF4434 PF14488.6 GAM19263.1 - 0.0019 18.3 0.1 0.0032 17.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) GHL6 PF14871.6 GAM19263.1 - 0.048 13.8 0.2 0.075 13.2 0.2 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 zf-CCHC PF00098.23 GAM19264.1 - 2.2e-37 125.5 45.4 4.8e-08 32.7 2.3 5.3 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 GAM19264.1 - 5e-07 29.4 24.9 0.36 10.6 0.2 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 GAM19264.1 - 6.7e-07 29.2 35.5 0.046 13.7 0.5 5.2 2 1 3 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 GAM19264.1 - 5.1e-06 26.2 35.4 0.13 12.2 1.8 5.3 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_5 PF14787.6 GAM19264.1 - 0.056 13.2 30.7 0.69 9.7 1.6 5.2 3 1 2 5 5 5 0 GAG-polyprotein viral zinc-finger Gla PF00594.20 GAM19264.1 - 3.4 8.0 8.7 30 4.9 0.1 4.2 4 0 0 4 4 4 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain CENP-N PF05238.13 GAM19264.1 - 3.5 6.8 9.2 4.5 6.5 9.2 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like zf-HC5HC2H_2 PF13832.6 GAM19266.1 - 3.7e-23 81.8 6.1 3.7e-23 81.8 6.1 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 GAM19266.1 - 1.5e-22 80.7 1.2 1.5e-22 80.7 1.2 4.7 3 2 1 4 4 4 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 GAM19266.1 - 7.3e-18 64.6 2.8 7.3e-18 64.6 2.8 3.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 GAM19266.1 - 6.1e-17 61.5 0.3 1.9e-16 59.9 0.3 1.9 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 GAM19266.1 - 7.3e-13 47.8 5.1 7.3e-13 47.8 5.1 2.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 GAM19266.1 - 2.5e-12 46.5 25.5 5.1e-10 39.1 7.3 3.4 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.22 GAM19266.1 - 0.0064 16.4 0.9 0.0064 16.4 0.9 3.4 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 GAM19266.1 - 6 6.4 24.2 0.018 14.7 3.9 3.7 2 2 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.11 GAM19266.1 - 6.1 7.2 23.5 0.045 14.1 7.1 2.9 2 1 0 2 2 2 0 RING-like domain DUF1990 PF09348.10 GAM19267.1 - 4.1e-44 150.3 0.1 5.7e-44 149.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) UPF0183 PF03676.14 GAM19269.1 - 8.2e-100 334.8 6.4 1.2e-78 265.1 3.8 3.0 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) CHCH PF06747.13 GAM19270.1 - 0.012 15.7 1.7 0.012 15.7 1.7 2.9 2 1 1 3 3 3 0 CHCH domain SP2 PF03014.14 GAM19270.1 - 0.046 12.1 0.0 0.058 11.8 0.0 1.1 1 0 0 1 1 1 0 Structural protein 2 CX9C PF16860.5 GAM19270.1 - 0.053 13.5 8.9 0.18 11.8 2.5 2.6 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 GAM19270.1 - 0.14 12.2 9.8 1.9 8.6 0.8 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.11 GAM19270.1 - 0.69 10.4 3.9 3.4 8.2 0.2 2.3 2 0 0 2 2 2 0 GCK domain Dickkopf_N PF04706.12 GAM19270.1 - 1.1 9.8 6.0 9.6 6.8 2.3 2.3 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Pet191_N PF10203.9 GAM19270.1 - 4.3 7.7 13.5 6.3 7.2 8.4 2.8 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 VPS9 PF02204.18 GAM19271.1 - 3.1e-28 98.0 1.1 8.4e-28 96.6 0.2 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain LETM1 PF07766.13 GAM19272.1 - 1.9e-85 286.4 6.8 1.9e-85 286.4 6.8 1.8 2 0 0 2 2 2 1 LETM1-like protein Utp12 PF04003.12 GAM19272.1 - 0.044 14.1 0.1 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Dip2/Utp12 Family Amidinotransf PF02274.17 GAM19273.1 - 3.6e-57 194.0 2.7 6.9e-50 170.1 0.2 2.0 2 0 0 2 2 2 2 Amidinotransferase Imm43 PF15570.6 GAM19273.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 43 PP2C PF00481.21 GAM19275.1 - 5.8e-53 180.2 0.0 1.3e-52 179.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.6 GAM19275.1 - 4.1e-05 23.3 11.5 0.018 15.1 0.1 5.2 5 0 0 5 5 5 3 Leucine Rich repeat PP2C_2 PF13672.6 GAM19275.1 - 0.0015 18.2 0.0 0.0048 16.6 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Pro-rich PF15240.6 GAM19276.1 - 0.0046 17.3 0.9 0.0054 17.0 0.9 1.2 1 0 0 1 1 1 1 Proline-rich FAM176 PF14851.6 GAM19276.1 - 0.011 15.5 1.4 0.013 15.1 1.4 1.1 1 0 0 1 1 1 0 FAM176 family DUF4820 PF16091.5 GAM19276.1 - 0.014 14.8 0.7 0.017 14.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) ETRAMP PF09716.10 GAM19276.1 - 0.016 15.2 2.8 0.032 14.3 2.8 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CemA PF03040.14 GAM19276.1 - 0.021 14.8 0.4 0.021 14.8 0.4 1.1 1 0 0 1 1 1 0 CemA family WBP-1 PF11669.8 GAM19276.1 - 0.026 15.2 1.1 0.037 14.7 1.1 1.4 1 1 0 1 1 1 0 WW domain-binding protein 1 PCEMA1 PF07418.11 GAM19276.1 - 0.041 13.4 6.1 0.047 13.2 6.1 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 SID-1_RNA_chan PF13965.6 GAM19276.1 - 0.047 12.1 1.3 0.054 11.9 1.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Orai-1 PF07856.12 GAM19276.1 - 0.051 13.3 0.1 0.072 12.8 0.1 1.2 1 0 0 1 1 1 0 Mediator of CRAC channel activity O-antigen_lig PF13425.6 GAM19276.1 - 0.051 12.4 0.9 0.05 12.4 0.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CLN3 PF02487.17 GAM19276.1 - 0.093 11.8 0.8 0.098 11.7 0.8 1.0 1 0 0 1 1 1 0 CLN3 protein Lig_chan PF00060.26 GAM19276.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Ligand-gated ion channel DUF4446 PF14584.6 GAM19276.1 - 0.11 12.5 0.8 0.15 12.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Ndc1_Nup PF09531.10 GAM19276.1 - 0.13 10.9 1.2 0.14 10.8 1.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF775 PF05603.12 GAM19276.1 - 2.3 7.7 8.4 2.9 7.4 8.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF775) Pkinase PF00069.25 GAM19278.1 - 7.9e-45 153.3 0.0 8.9e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19278.1 - 1.2e-19 70.6 0.0 1.4e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM19278.1 - 2.2e-05 23.9 0.0 5.2e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAM19278.1 - 0.0026 17.1 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM19278.1 - 0.0093 14.8 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 GAM19278.1 - 0.039 13.6 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 GAM19279.1 - 3.6e-05 23.3 0.7 7.2e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain TFIIA PF03153.13 GAM19279.1 - 0.034 14.2 20.7 0.053 13.5 20.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Membralin PF09746.9 GAM19279.1 - 0.17 10.9 7.0 0.27 10.2 7.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein S36_mt PF10937.8 GAM19279.1 - 0.53 11.9 7.3 0.58 11.8 5.7 1.9 1 1 0 1 1 1 0 Ribosomal protein S36, mitochondrial Macoilin PF09726.9 GAM19279.1 - 1.1 7.8 11.3 1.4 7.4 11.3 1.1 1 0 0 1 1 1 0 Macoilin family Mucin PF01456.17 GAM19279.1 - 3.6 7.6 25.6 0.23 11.4 19.8 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein FNIP PF05725.12 GAM19280.1 - 4.7e-28 97.1 18.7 9e-13 48.2 1.6 5.2 5 1 0 5 5 5 4 FNIP Repeat Acetyltransf_7 PF13508.7 GAM19281.1 - 5.6e-08 33.1 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM19281.1 - 3.8e-07 30.1 0.5 1.5e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM19281.1 - 4.6e-07 30.1 0.0 9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAM19281.1 - 3e-05 23.9 0.0 6.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein LMBR1 PF04791.16 GAM19281.1 - 4.7 6.0 9.1 6.7 5.5 9.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Porin_3 PF01459.22 GAM19282.1 - 9.7e-27 94.1 0.3 1.1e-26 93.9 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Porin_7 PF16956.5 GAM19282.1 - 0.0036 17.0 0.1 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 Putative general bacterial porin OMP_b-brl PF13505.6 GAM19282.1 - 0.042 14.0 2.6 0.16 12.1 2.6 2.0 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain STATa_Ig PF18214.1 GAM19283.1 - 6.5e-05 22.9 0.1 6.5e-05 22.9 0.1 2.4 2 1 0 2 2 2 1 STATa Immunoglobulin-like domain DUF3048_C PF17479.2 GAM19283.1 - 0.027 14.8 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) C-terminal domain SnAC PF14619.6 GAM19283.1 - 0.15 12.7 0.8 0.32 11.6 0.8 1.6 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex GREB1 PF15782.5 GAM19283.1 - 0.95 6.5 15.9 1.3 6.0 15.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RsbU_N PF08673.10 GAM19284.1 - 0.24 11.5 4.0 28 4.9 0.0 3.5 3 1 1 4 4 4 0 Phosphoserine phosphatase RsbU, N-terminal domain SAP30_Sin3_bdg PF13867.6 GAM19285.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Sec23_trunk PF04811.15 GAM19286.1 - 3.1e-43 148.1 0.0 5.8e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAM19286.1 - 4.5e-21 74.6 0.0 4.5e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAM19286.1 - 4e-17 62.7 0.0 1e-16 61.4 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAM19286.1 - 8.9e-12 44.9 5.6 1.4e-11 44.2 3.9 2.2 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAM19286.1 - 3.2e-07 30.1 0.1 1.5e-06 28.0 0.1 2.2 1 0 0 1 1 1 1 Gelsolin repeat G8 PF10162.9 GAM19287.1 - 2.3e-25 89.0 0.3 4.7e-25 88.0 0.3 1.5 1 0 0 1 1 1 1 G8 domain Amnionless PF14828.6 GAM19287.1 - 0.045 12.6 0.1 0.07 11.9 0.1 1.2 1 0 0 1 1 1 0 Amnionless ketoacyl-synt PF00109.26 GAM19288.1 - 1.1e-72 244.7 0.0 2e-72 243.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 GAM19288.1 - 5.4e-53 179.8 0.0 1.3e-52 178.5 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 GAM19288.1 - 4.1e-45 154.7 0.0 1.1e-44 153.2 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM19288.1 - 1e-40 138.4 0.3 3.3e-40 136.8 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 GAM19288.1 - 1.4e-35 122.8 0.1 2.3e-34 118.9 0.3 2.4 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 GAM19288.1 - 1.4e-23 83.6 0.0 2.4e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 GAM19288.1 - 3.8e-16 59.5 0.1 1.5e-15 57.6 0.1 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 GAM19288.1 - 1.1e-12 49.1 0.1 3.2e-11 44.4 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 GAM19288.1 - 7.7e-08 32.0 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 GAM19288.1 - 2.6e-07 29.9 0.3 7e-07 28.5 0.3 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 GAM19288.1 - 2.8e-07 30.8 0.0 9e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 GAM19288.1 - 8.7e-06 25.6 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.12 GAM19288.1 - 0.026 15.2 0.0 0.13 13.1 0.0 2.3 1 0 0 1 1 1 0 Methyltransferase domain SapB_2 PF03489.17 GAM19289.1 - 0.017 15.2 1.4 0.056 13.6 0.7 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 2 DSPc PF00782.20 GAM19290.1 - 2.3e-32 111.6 0.0 2.3e-32 111.6 0.0 2.3 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM19290.1 - 0.0042 16.7 4.1 0.0046 16.6 0.1 2.2 1 1 1 3 3 3 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAM19290.1 - 0.014 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate zf-RING_2 PF13639.6 GAM19291.1 - 3.3e-11 43.3 6.3 7.9e-11 42.1 6.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM19291.1 - 4.2e-08 32.9 5.7 9.2e-08 31.8 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM19291.1 - 6.1e-08 32.8 3.1 1.8e-07 31.3 3.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAM19291.1 - 8.2e-08 31.9 2.8 1.8e-07 30.8 2.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 GAM19291.1 - 3.1e-07 30.2 3.0 5.9e-07 29.2 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM19291.1 - 3.4e-07 30.1 3.4 7.1e-07 29.1 3.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAM19291.1 - 1.6e-06 27.8 6.6 3.9e-06 26.6 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM19291.1 - 4.6e-05 23.2 4.2 9.4e-05 22.2 4.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAM19291.1 - 0.00048 20.1 1.3 0.0014 18.6 1.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAM19291.1 - 0.001 19.1 2.3 0.003 17.5 2.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 GAM19291.1 - 0.0048 16.7 6.5 0.012 15.4 6.5 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 GAM19291.1 - 0.017 14.7 2.9 0.038 13.6 2.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF722 PF05263.11 GAM19291.1 - 0.064 13.5 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF722) RINGv PF12906.7 GAM19291.1 - 0.13 12.4 6.0 0.42 10.8 6.0 1.9 1 0 0 1 1 1 0 RING-variant domain NTP_transferase PF00483.23 GAM19292.1 - 1e-26 94.0 0.0 1.3e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 GAM19292.1 - 5.6e-07 29.0 8.0 6.6e-07 28.8 1.1 3.5 4 1 0 4 4 4 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 GAM19292.1 - 3.1e-06 27.6 0.0 4.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 GAM19292.1 - 0.15 10.2 0.1 0.22 9.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 GAM19292.1 - 1.1 9.1 5.4 0.45 10.3 0.3 3.0 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase ATG19_autophagy PF12744.7 GAM19293.1 - 0.056 12.6 0.9 0.074 12.2 0.9 1.2 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding Ank_2 PF12796.7 GAM19294.1 - 5.3e-10 39.8 13.1 0.71 10.5 0.0 8.9 6 2 2 8 8 8 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM19294.1 - 9.1e-06 25.7 7.2 87 4.2 0.0 10.4 12 0 0 12 12 12 0 Ankyrin repeat Ank_5 PF13857.6 GAM19294.1 - 0.00033 20.9 4.5 44 4.5 0.0 7.6 9 0 0 9 9 9 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM19294.1 - 0.0024 18.4 15.6 25 5.6 0.2 9.3 11 1 1 12 12 12 1 Ankyrin repeats (many copies) LBR_tudor PF09465.10 GAM19296.1 - 1.3e-05 24.9 0.3 2.5e-05 24.0 0.3 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Agenet PF05641.12 GAM19296.1 - 0.00012 22.4 0.1 0.00022 21.6 0.1 1.4 1 0 0 1 1 1 1 Agenet domain TssN PF17555.2 GAM19296.1 - 0.2 11.0 0.1 0.37 10.1 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN MAGE_N PF12440.8 GAM19296.1 - 0.31 11.8 6.9 18 6.1 4.4 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal SSP160 PF06933.11 GAM19296.1 - 0.37 9.0 13.5 0.49 8.5 13.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 GAM19296.1 - 0.7 9.9 17.7 1.1 9.2 17.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Holin_SPP1 PF04688.13 GAM19296.1 - 3.9 7.7 6.3 1.9 8.7 0.8 2.3 2 0 0 2 2 2 0 SPP1 phage holin DUF1258 PF06869.12 GAM19297.1 - 0.029 13.9 0.3 1.1 8.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) Ank_2 PF12796.7 GAM19298.1 - 7.1e-10 39.3 11.7 0.089 13.4 0.1 8.0 7 1 1 8 8 8 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19298.1 - 1.4e-06 28.7 4.7 6.1 7.5 0.0 8.7 7 1 0 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19298.1 - 0.0002 21.6 7.4 70 4.5 0.0 8.9 10 0 0 10 10 10 0 Ankyrin repeat DUF3447 PF11929.8 GAM19298.1 - 0.29 11.1 12.9 37 4.4 0.0 6.6 4 2 1 5 5 5 0 Domain of unknown function (DUF3447) Ank_2 PF12796.7 GAM19299.1 - 2e-07 31.5 1.8 0.38 11.4 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19299.1 - 0.00075 20.0 1.9 19 6.0 0.0 5.7 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM19299.1 - 0.0023 18.2 0.9 1.2 9.6 0.0 4.9 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19299.1 - 0.019 15.5 0.4 13 6.7 0.0 5.2 6 0 0 6 6 6 0 Ankyrin repeat Ank_3 PF13606.6 GAM19300.1 - 5.1e-06 26.4 2.7 0.55 11.0 0.0 5.6 7 0 0 7 7 7 2 Ankyrin repeat Ank_2 PF12796.7 GAM19300.1 - 4.4e-05 24.0 1.4 0.0023 18.5 0.2 3.4 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19300.1 - 0.0055 17.3 3.1 0.5 11.0 0.0 4.0 4 1 1 5 5 5 1 Ankyrin repeats (many copies) PPR_3 PF13812.6 GAM19300.1 - 0.06 13.4 0.1 1.9 8.6 0.0 2.9 3 0 0 3 3 3 0 Pentatricopeptide repeat domain RNA_pol_Rpb4 PF03874.16 GAM19300.1 - 0.094 13.0 0.1 35 4.7 0.0 3.2 1 1 1 2 2 2 0 RNA polymerase Rpb4 DUF1843 PF08898.10 GAM19300.1 - 0.15 12.5 0.0 4.3 7.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Ank_2 PF12796.7 GAM19301.1 - 0.001 19.6 7.9 3.1 8.5 0.1 5.3 3 2 4 7 7 7 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19301.1 - 0.002 18.7 5.5 0.58 10.8 0.0 5.8 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19301.1 - 0.0073 16.7 5.6 41 5.2 0.0 7.4 7 1 0 7 7 7 1 Ankyrin repeat Ank_2 PF12796.7 GAM19302.1 - 7e-07 29.7 0.4 0.9 10.2 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19302.1 - 0.00027 21.4 1.9 3.9 8.2 0.0 5.8 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19302.1 - 0.0057 17.1 1.9 2.6 8.9 0.0 5.9 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 GAM19302.1 - 0.033 14.5 2.2 29 5.1 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Adeno_E3A PF05248.12 GAM19302.1 - 0.054 13.5 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Adenovirus E3A Ank_2 PF12796.7 GAM19304.1 - 0.0004 20.9 5.0 0.0039 17.7 0.4 4.5 4 2 2 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19304.1 - 0.0047 17.5 1.8 4 8.1 0.1 5.9 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19304.1 - 0.2 12.3 2.8 44 5.1 0.0 5.9 6 0 0 6 6 6 0 Ankyrin repeat Acetyltransf_10 PF13673.7 GAM19305.1 - 8.1e-14 51.7 0.0 9.9e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM19305.1 - 4.4e-10 39.8 0.6 6.8e-10 39.2 0.6 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM19305.1 - 1.3e-09 38.3 0.1 1.7e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAM19305.1 - 5.4e-05 23.1 0.0 9.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_5 PF13444.6 GAM19305.1 - 0.00017 22.3 0.2 0.0063 17.2 0.2 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM19305.1 - 0.026 14.6 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 GAM19305.1 - 0.097 12.7 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RL10P_insert PF17777.1 GAM19306.1 - 2.5e-21 75.4 0.4 5.1e-21 74.5 0.4 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 GAM19306.1 - 1.4e-17 63.6 1.4 2.5e-17 62.8 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 GAM19306.1 - 1e-15 58.1 6.6 1e-15 58.1 6.6 2.4 3 0 0 3 3 3 1 60s Acidic ribosomal protein NUMOD3 PF07460.11 GAM19306.1 - 0.17 12.1 0.2 0.39 11.0 0.2 1.6 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) Amidohydro_2 PF04909.14 GAM19307.1 - 2.3e-59 201.6 0.0 2.6e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Peptidase_M19 PF01244.21 GAM19307.1 - 0.16 11.1 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Kelch_1 PF01344.25 GAM19308.1 - 2.4e-07 30.2 8.4 0.013 15.1 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM19308.1 - 5.7e-05 23.1 8.1 0.46 10.5 0.1 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM19308.1 - 6.3e-05 23.1 12.0 0.54 10.6 0.1 5.5 4 1 1 5 5 5 3 Kelch motif NUP214 PF16755.5 GAM19308.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Kelch_2 PF07646.15 GAM19308.1 - 0.081 12.9 6.2 8.8 6.5 0.1 4.6 5 0 0 5 5 5 0 Kelch motif STN PF07660.14 GAM19308.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain Kelch_3 PF13415.6 GAM19308.1 - 4 7.8 12.0 11 6.4 0.0 5.5 7 0 0 7 7 7 0 Galactose oxidase, central domain YchF-GTPase_C PF06071.13 GAM19309.1 - 7.7e-40 135.0 0.6 1.7e-39 133.9 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 GAM19309.1 - 1.2e-19 70.5 0.0 4.1e-19 68.7 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM19309.1 - 2.5e-06 27.1 0.0 4.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 GAM19309.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MR_MLE_C PF13378.6 GAM19310.1 - 7.7e-58 195.6 0.0 1.2e-57 195.0 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAM19310.1 - 1.5e-06 28.4 0.0 5.3e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF5420 PF17457.2 GAM19310.1 - 0.099 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5420) COX6B PF02297.17 GAM19311.1 - 4.2e-18 65.3 4.9 4.2e-18 65.3 4.9 1.5 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb SNF2_N PF00176.23 GAM19312.1 - 1.2e-68 231.5 0.1 3.4e-68 229.9 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM19312.1 - 3.8e-16 59.4 0.1 2.5e-15 56.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 GAM19312.1 - 7.9e-15 54.7 1.1 4.9e-14 52.2 1.1 2.4 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 GAM19312.1 - 2e-09 37.7 0.0 2e-09 37.7 0.0 4.2 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit HSA PF07529.13 GAM19312.1 - 4.1e-09 36.6 10.0 4.1e-09 36.6 10.0 4.0 2 1 0 2 2 2 1 HSA QLQ PF08880.11 GAM19312.1 - 0.00022 20.9 0.1 0.00053 19.7 0.1 1.7 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 GAM19312.1 - 0.00024 21.6 4.2 0.00024 21.6 4.2 5.2 4 2 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex zf-HIT PF04438.16 GAM19313.1 - 0.0011 18.8 5.6 0.0015 18.3 5.6 1.2 1 0 0 1 1 1 1 HIT zinc finger MCD PF05292.11 GAM19313.1 - 0.058 13.0 0.8 0.077 12.6 0.8 1.1 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain PCRF PF03462.18 GAM19313.1 - 0.57 10.0 5.6 0.93 9.3 5.6 1.3 1 0 0 1 1 1 0 PCRF domain SDA1 PF05285.12 GAM19313.1 - 0.68 9.3 32.5 1 8.7 32.5 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GAM19313.1 - 5.4 5.2 24.0 7 4.8 24.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 GAM19314.1 - 1 9.3 8.2 2.1 8.3 8.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 GAM19314.1 - 5 5.9 12.3 8 5.2 12.3 1.2 1 0 0 1 1 1 0 Androgen receptor SdrD_B PF17210.3 GAM19315.1 - 1.8e-15 57.1 7.2 2.8e-06 27.5 0.1 4.3 4 1 0 4 4 4 3 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM19315.1 - 0.035 14.4 2.9 2.4 8.5 0.2 3.3 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain RhoGAP PF00620.27 GAM19316.1 - 1.1e-30 106.5 0.0 2.7e-30 105.2 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain RPEL PF02755.15 GAM19316.1 - 0.0014 18.2 0.8 0.0043 16.7 0.8 1.8 1 0 0 1 1 1 1 RPEL repeat DUF1708 PF08101.11 GAM19316.1 - 0.035 13.3 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) VLPT PF07122.11 GAM19316.1 - 1.2 9.0 4.0 30 4.5 0.0 3.6 4 0 0 4 4 4 0 Variable length PCR target protein (VLPT) Aldo_ket_red PF00248.21 GAM19317.1 - 1.3e-05 24.5 0.0 2.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L13 PF00572.18 GAM19318.1 - 6.5e-46 155.6 0.3 6.5e-46 155.6 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 BTB_2 PF02214.22 GAM19319.1 - 1.4e-13 51.0 0.0 4.7e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DUSP PF06337.12 GAM19319.1 - 4.4e-12 46.5 0.1 2.2e-11 44.2 0.0 2.1 2 1 0 2 2 2 1 DUSP domain DCP1 PF06058.13 GAM19319.1 - 0.00017 21.5 0.1 0.00049 20.0 0.0 1.8 2 0 0 2 2 2 1 Dcp1-like decapping family FtsX PF02687.21 GAM19320.1 - 3.2e-13 50.0 21.7 4.5e-09 36.7 5.5 6.0 6 1 0 6 6 6 2 FtsX-like permease family eIF-3_zeta PF05091.12 GAM19321.1 - 5.4e-151 504.1 1.1 6.1e-151 503.9 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 GAM19321.1 - 7.6e-05 22.3 0.0 0.00027 20.5 0.0 1.9 2 0 0 2 2 2 1 NMDA receptor-regulated gene protein 2 C-terminus NUFIP1 PF10453.9 GAM19322.1 - 3.8e-13 49.1 4.3 3.8e-13 49.1 4.3 2.7 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) PH_10 PF15411.6 GAM19322.1 - 3.4 7.9 7.3 0.25 11.6 0.9 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Mucin PF01456.17 GAM19322.1 - 9.1 6.3 17.5 2 8.4 13.8 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein NARG2_C PF10505.9 GAM19323.1 - 4.7e-23 81.8 0.4 1.6e-22 80.1 0.0 2.0 2 0 0 2 2 2 1 NMDA receptor-regulated gene protein 2 C-terminus zf-CCCH PF00642.24 GAM19323.1 - 0.032 14.1 1.1 0.064 13.2 1.1 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_2 PF07646.15 GAM19324.1 - 0.079 13.0 0.2 0.91 9.6 0.0 2.8 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 GAM19324.1 - 0.64 10.1 5.4 1.4 9.0 0.3 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain Endotoxin_N PF03945.14 GAM19325.1 - 4.8e-41 140.9 4.3 4.8e-41 140.9 4.3 1.7 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain Phage_Gp19 PF09355.10 GAM19327.1 - 0.17 12.3 2.0 0.24 11.8 2.0 1.3 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 Borrelia_orfD PF02999.14 GAM19328.1 - 0.03 14.6 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 Borrelia orf-D family TSP_3 PF02412.18 GAM19328.1 - 2.6 7.8 11.4 2.1 8.1 6.1 2.6 2 0 0 2 2 2 0 Thrombospondin type 3 repeat EF-hand_5 PF13202.6 GAM19329.1 - 1.1 8.9 15.2 0.51 9.9 1.8 3.4 3 0 0 3 3 3 0 EF hand TSP_3 PF02412.18 GAM19329.1 - 3.2 7.5 11.9 1.9 8.2 6.1 2.6 2 0 0 2 2 2 0 Thrombospondin type 3 repeat 2OG-FeII_Oxy_3 PF13640.6 GAM19332.1 - 1.4e-12 48.3 0.0 2.2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 GAM19332.1 - 4e-05 23.9 0.0 6.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Oxygenase-NA PF09859.9 GAM19332.1 - 0.024 14.2 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Ribosomal_60s PF00428.19 GAM19333.1 - 1e-24 86.9 10.4 1.2e-24 86.7 10.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3123 PF11321.8 GAM19333.1 - 0.036 14.7 0.4 0.045 14.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF3824 PF12868.7 GAM19333.1 - 0.66 10.6 5.8 1.1 10.0 5.8 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) OAD_gamma PF04277.13 GAM19334.1 - 0.61 10.7 8.5 0.39 11.3 0.4 4.6 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DNA_pol_phi PF04931.13 GAM19335.1 - 0.24 9.5 16.8 0.34 9.0 16.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GAM19335.1 - 0.24 10.8 13.7 0.41 10.0 13.7 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GAM19335.1 - 0.31 9.2 16.3 0.48 8.6 16.3 1.2 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 GAM19335.1 - 0.54 8.0 9.3 0.91 7.2 9.3 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3439 PF11921.8 GAM19335.1 - 0.73 9.8 10.8 1.9 8.4 10.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Astro_capsid_p PF12226.8 GAM19335.1 - 1.8 7.6 21.2 0.054 12.7 14.9 1.6 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Cwf_Cwc_15 PF04889.12 GAM19335.1 - 2.3 7.9 16.4 6.3 6.5 16.4 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BSP_II PF05432.11 GAM19335.1 - 2.4 7.8 22.4 5.4 6.6 22.4 1.6 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RRN3 PF05327.11 GAM19335.1 - 2.5 6.5 11.6 3.9 5.9 11.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 GAM19335.1 - 5.6 5.1 11.7 8.7 4.5 11.7 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 GAM19335.1 - 8.7 5.6 13.1 14 4.9 13.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cnd1 PF12717.7 GAM19336.1 - 2.9e-36 124.9 3.3 5.5e-26 91.5 0.0 4.9 3 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAM19336.1 - 2.2e-10 39.9 7.0 0.12 12.7 0.4 6.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 GAM19336.1 - 4.9e-07 30.1 2.5 0.028 14.8 0.0 4.6 3 1 1 4 4 4 2 HEAT repeats Adaptin_N PF01602.20 GAM19336.1 - 4.6e-06 25.5 9.9 0.00017 20.3 0.2 3.1 2 1 1 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.7 GAM19336.1 - 6.9e-05 22.2 5.2 0.0029 16.8 0.1 3.3 2 1 1 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 GAM19336.1 - 0.0001 22.7 4.8 1.1 9.8 0.0 5.4 5 1 1 6 6 6 1 HEAT-like repeat PBP1_TM PF14812.6 GAM19336.1 - 0.014 15.7 0.3 0.014 15.7 0.3 4.9 3 1 1 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.18 GAM19336.1 - 0.018 15.0 36.5 0.62 9.9 0.4 4.2 3 1 0 3 3 3 0 Myc amino-terminal region Cohesin_HEAT PF12765.7 GAM19336.1 - 0.044 14.1 4.8 0.62 10.4 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion PTS_EIIA_2 PF00359.22 GAM19336.1 - 0.053 13.4 1.2 11 5.9 0.1 2.7 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 TFCD_C PF12612.8 GAM19336.1 - 0.091 12.6 1.2 0.32 10.8 0.3 2.4 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal RNA_pol_3_Rpc31 PF11705.8 GAM19336.1 - 0.2 11.9 43.0 0.046 14.0 11.5 3.4 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 GAM19336.1 - 0.24 11.2 39.1 1.1 9.0 9.7 3.9 3 0 0 3 3 3 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 GAM19336.1 - 0.96 9.5 30.5 2.1 8.4 8.4 3.9 3 0 0 3 3 3 0 RXT2-like, N-terminal NOA36 PF06524.12 GAM19336.1 - 4.5 6.5 49.6 1.4 8.2 12.7 3.4 3 0 0 3 3 3 0 NOA36 protein CENP-L PF13092.6 GAM19337.1 - 0.14 12.3 1.3 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 zf-C3HC4_3 PF13920.6 GAM19337.1 - 9 6.2 15.2 3 7.8 11.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HutD PF05962.11 GAM19338.1 - 2.5e-28 99.3 0.1 1.5e-24 87.0 0.0 3.0 2 1 0 2 2 2 2 HutD FNIP PF05725.12 GAM19339.1 - 5.8e-54 180.0 16.4 1.4e-14 54.0 0.3 7.9 6 2 3 9 9 9 6 FNIP Repeat LRR_1 PF00560.33 GAM19339.1 - 0.015 15.8 4.3 11 7.0 0.1 6.0 5 1 0 5 5 5 0 Leucine Rich Repeat Myosin_head PF00063.21 GAM19340.1 - 6.2e-288 956.7 0.7 6.2e-288 956.7 0.7 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 GAM19340.1 - 1.1e-75 255.3 316.3 4.4e-45 154.0 158.4 3.2 1 1 2 3 3 3 2 Myosin tail Myosin_N PF02736.19 GAM19340.1 - 1.1e-09 38.0 0.1 2.7e-09 36.7 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 GAM19340.1 - 5e-09 36.2 270.0 3.6e-05 23.5 17.1 10.8 1 1 8 9 9 9 6 Intermediate filament protein ATG16 PF08614.11 GAM19340.1 - 2.7e-05 24.5 21.2 2.7e-05 24.5 21.2 11.4 1 1 9 10 10 6 1 Autophagy protein 16 (ATG16) BRE1 PF08647.11 GAM19340.1 - 0.0001 22.3 37.2 0.00024 21.1 16.8 16.3 5 4 10 16 16 14 3 BRE1 E3 ubiquitin ligase IQ PF00612.27 GAM19340.1 - 0.00083 18.9 2.3 0.0021 17.7 0.9 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif CENP-F_leu_zip PF10473.9 GAM19340.1 - 0.0034 17.4 29.6 0.0034 17.4 29.6 13.0 2 2 10 13 13 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XPC-binding PF09280.11 GAM19340.1 - 0.14 11.9 1.6 12 5.7 0.1 3.8 3 0 0 3 3 3 0 XPC-binding domain AAA_22 PF13401.6 GAM19340.1 - 0.3 11.4 0.0 0.3 11.4 0.0 5.2 7 2 1 8 8 8 0 AAA domain AAA_19 PF13245.6 GAM19340.1 - 0.92 9.8 5.6 0.4 11.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain Imm8 PF15586.6 GAM19341.1 - 0.12 12.4 0.2 2.1 8.4 0.0 2.6 3 0 0 3 3 3 0 Immunity protein 8 ComA PF02679.15 GAM19342.1 - 0.0039 16.7 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Ank_2 PF12796.7 GAM19343.1 - 0.28 11.8 2.4 62 4.3 0.1 4.2 4 0 0 4 4 4 0 Ankyrin repeats (3 copies) FUN14 PF04930.15 GAM19344.1 - 4.7e-18 65.4 0.1 4.7e-18 65.4 0.1 2.3 1 1 1 2 2 2 1 FUN14 family ETRAMP PF09716.10 GAM19344.1 - 0.051 13.6 3.0 0.32 11.1 2.9 2.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) AI-2E_transport PF01594.16 GAM19344.1 - 0.07 12.3 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 AI-2E family transporter Trp_oprn_chp PF09534.10 GAM19344.1 - 0.14 11.9 5.0 0.093 12.5 0.7 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EGF_2 PF07974.13 GAM19345.1 - 0.00093 19.5 9.7 0.0021 18.4 9.7 1.7 1 0 0 1 1 1 1 EGF-like domain TIG PF01833.24 GAM19345.1 - 0.0024 17.9 19.3 0.035 14.2 0.9 4.6 4 0 0 4 4 4 3 IPT/TIG domain EB PF01683.18 GAM19345.1 - 0.024 14.9 2.9 0.066 13.5 2.9 1.7 1 0 0 1 1 1 0 EB module Pollen_Ole_e_I PF01190.17 GAM19345.1 - 0.044 14.2 0.2 0.93 9.9 0.0 2.7 2 0 0 2 2 2 0 Pollen proteins Ole e I like I-EGF_1 PF18372.1 GAM19345.1 - 0.1 12.7 8.6 0.028 14.5 5.1 2.0 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 hEGF PF12661.7 GAM19345.1 - 2.1 9.1 11.3 0.86 10.3 6.4 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF Fz PF01392.22 GAM19346.1 - 2.3e-07 31.4 4.8 6.3e-07 30.0 4.8 1.7 1 0 0 1 1 1 1 Fz domain CAML PF14963.6 GAM19347.1 - 0.021 14.9 4.0 0.032 14.4 4.0 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Tfb4 PF03850.14 GAM19347.1 - 0.041 13.4 2.9 0.061 12.8 2.9 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 UPF0449 PF15136.6 GAM19347.1 - 0.053 14.0 0.8 0.1 13.1 0.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 SR-25 PF10500.9 GAM19347.1 - 5 6.7 12.3 8 6.0 12.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 GAM19347.1 - 6.8 5.1 10.6 9.4 4.6 10.6 1.1 1 0 0 1 1 1 0 Macoilin family TMEM223 PF14640.6 GAM19348.1 - 0.075 13.2 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Transmembrane protein 223 EGF_2 PF07974.13 GAM19348.1 - 0.48 10.9 15.3 2 8.9 15.3 2.1 1 0 0 1 1 1 0 EGF-like domain Pur_ac_phosph_N PF16656.5 GAM19348.1 - 0.5 11.0 3.0 0.49 11.0 0.2 2.4 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain EB PF01683.18 GAM19349.1 - 0.0034 17.6 5.0 0.0076 16.5 5.0 1.5 1 0 0 1 1 1 1 EB module EGF_2 PF07974.13 GAM19349.1 - 0.022 15.1 18.5 0.052 13.9 18.5 1.7 1 0 0 1 1 1 0 EGF-like domain I-EGF_1 PF18372.1 GAM19349.1 - 0.032 14.3 9.6 0.083 13.0 9.6 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 CEBP1_N PF16368.5 GAM19349.1 - 0.12 11.9 1.2 0.13 11.8 0.1 1.5 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus hEGF PF12661.7 GAM19349.1 - 3.6 8.4 12.6 3.2 8.5 9.1 2.5 2 0 0 2 2 2 0 Human growth factor-like EGF DUF1996 PF09362.10 GAM19350.1 - 1.9e-34 119.7 1.8 3e-34 119.1 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Polysacc_lyase PF14099.6 GAM19351.1 - 2.4e-13 50.4 6.1 3.1e-13 50.1 6.1 1.1 1 0 0 1 1 1 1 Polysaccharide lyase Polysacc_lyase PF14099.6 GAM19352.1 - 3.2e-14 53.3 3.7 4.4e-14 52.8 3.7 1.2 1 0 0 1 1 1 1 Polysaccharide lyase Sporozoite_P67 PF05642.11 GAM19352.1 - 0.044 11.9 0.1 0.036 12.2 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 GAM19352.1 - 0.85 9.6 14.6 0.21 11.6 9.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.11 GAM19352.1 - 2.9 6.0 10.2 4.5 5.4 10.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Methyltr_RsmB-F PF01189.17 GAM19353.1 - 3e-33 115.2 0.0 7.7e-17 61.6 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 GAM19353.1 - 3.8e-07 30.0 0.0 7.7e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM19353.1 - 1e-06 29.3 0.0 6.9e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAM19353.1 - 8.5e-05 22.2 0.0 0.00062 19.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 GAM19353.1 - 0.0002 20.8 0.0 0.0081 15.5 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 GAM19353.1 - 0.00024 21.3 0.2 0.002 18.3 0.2 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 GAM19353.1 - 0.00036 20.4 0.0 0.0011 18.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 GAM19353.1 - 0.017 14.3 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltr_RsmF_N PF17125.5 GAM19353.1 - 0.018 15.5 0.0 0.041 14.4 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_12 PF08242.12 GAM19353.1 - 0.027 15.2 1.5 2.8 8.7 0.0 3.4 4 0 0 4 4 4 0 Methyltransferase domain PCMT PF01135.19 GAM19353.1 - 0.027 14.2 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 GAM19353.1 - 0.041 14.5 0.1 0.96 10.1 0.0 2.9 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_4 PF02390.17 GAM19353.1 - 0.08 12.4 0.0 0.35 10.3 0.0 2.0 3 0 0 3 3 3 0 Putative methyltransferase PBP1_TM PF14812.6 GAM19353.1 - 0.16 12.4 9.0 0.53 10.7 2.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Menin PF05053.13 GAM19353.1 - 0.6 8.4 3.0 1.1 7.6 3.0 1.3 1 0 0 1 1 1 0 Menin Vfa1 PF08432.10 GAM19353.1 - 2.5 8.4 7.1 0.48 10.7 2.1 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 HeLo PF14479.6 GAM19354.1 - 0.0012 18.8 0.5 0.11 12.3 0.3 2.1 1 1 1 2 2 2 2 Prion-inhibition and propagation PAS_6 PF08348.11 GAM19354.1 - 0.052 13.4 0.4 0.052 13.4 0.4 1.9 2 1 0 2 2 2 0 YheO-like PAS domain FapA PF03961.13 GAM19354.1 - 0.29 9.7 3.4 0.34 9.4 3.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Kelch_6 PF13964.6 GAM19355.1 - 2.1e-12 46.8 7.5 4.8e-05 23.5 0.0 4.3 3 1 2 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAM19355.1 - 5.1e-11 42.0 3.3 0.0052 16.3 0.1 4.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM19355.1 - 1.2e-10 41.2 2.0 0.00012 22.0 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM19355.1 - 3.8e-08 33.0 0.5 0.024 14.6 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 GAM19355.1 - 0.00013 22.1 0.9 0.13 12.6 0.0 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM19355.1 - 0.0011 18.9 9.5 0.87 9.7 1.2 4.3 4 0 0 4 4 4 2 Kelch motif zf-CCCH_4 PF18044.1 GAM19356.1 - 0.0061 16.3 4.9 0.011 15.5 4.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAM19356.1 - 0.016 15.7 4.3 0.028 14.9 4.3 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 GAM19356.1 - 0.063 13.2 4.8 0.11 12.4 4.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAM19356.1 - 0.41 10.8 2.9 0.67 10.1 2.1 1.8 1 1 0 1 1 1 0 Zinc finger domain Ank_2 PF12796.7 GAM19357.1 - 1.4e-05 25.6 9.7 5.7 7.6 0.2 7.5 5 2 2 8 8 8 3 Ankyrin repeats (3 copies) ABC_transp_aux PF09822.9 GAM19357.1 - 0.022 14.3 0.1 0.047 13.2 0.1 1.5 1 0 0 1 1 1 0 ABC-type uncharacterized transport system PTPA PF03095.15 GAM19357.1 - 0.034 13.6 1.3 0.13 11.7 0.0 2.4 3 0 0 3 3 3 0 Phosphotyrosyl phosphate activator (PTPA) protein Coiled PF05710.12 GAM19358.1 - 2.8e-05 24.9 4.5 3.7e-05 24.5 4.5 1.2 1 1 0 1 1 1 1 Coiled coil DUF1911 PF08929.10 GAM19359.1 - 0.098 13.5 1.1 0.23 12.3 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1911) Trypan_PARP PF05887.11 GAM19360.1 - 0.68 9.9 4.6 1.7 8.6 4.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ank_2 PF12796.7 GAM19361.1 - 5.7e-10 39.7 4.4 0.023 15.3 0.1 7.2 5 2 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM19361.1 - 0.00036 20.7 3.3 46 5.1 0.0 8.2 9 1 1 10 10 10 1 Ankyrin repeat Ank PF00023.30 GAM19361.1 - 0.21 12.1 1.7 27 5.4 0.0 4.8 4 0 0 4 4 4 0 Ankyrin repeat Inositol_P PF00459.25 GAM19362.1 - 2.3e-47 161.8 0.0 3.2e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family STATa_Ig PF18214.1 GAM19364.1 - 1.5e-43 147.7 0.1 1.5e-43 147.7 0.1 3.1 3 0 0 3 3 3 1 STATa Immunoglobulin-like domain EF-hand_12 PF17901.1 GAM19364.1 - 2.6e-41 140.0 2.5 2.6e-41 140.0 2.5 2.8 4 0 0 4 4 4 1 EF-hand fold domain Dict-STAT-coil PF09267.10 GAM19364.1 - 2.9e-32 111.4 9.3 2.9e-32 111.4 9.3 4.8 2 1 3 5 5 5 1 Dictyostelium STAT, coiled coil SH2 PF00017.24 GAM19364.1 - 0.0014 18.7 0.1 0.015 15.4 0.0 2.7 2 0 0 2 2 2 1 SH2 domain DUF3799 PF12684.7 GAM19364.1 - 8.3 6.1 14.0 0.015 15.1 2.2 2.2 2 0 0 2 2 2 0 PDDEXK-like domain of unknown function (DUF3799) SRF-TF PF00319.18 GAM19365.1 - 6e-08 32.1 0.1 1.1e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PIF1 PF05970.14 GAM19367.1 - 2.2e-55 188.3 0.3 8.2e-44 150.2 0.0 3.0 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 GAM19367.1 - 2.2e-24 86.2 0.0 4.8e-24 85.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAM19367.1 - 4.8e-11 43.2 0.0 1.1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 GAM19367.1 - 3.7e-07 28.5 7.2 6.9e-05 21.0 0.0 2.7 4 0 0 4 4 3 2 Helicase AAA_22 PF13401.6 GAM19367.1 - 1.6e-05 25.2 0.1 6.1e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 GAM19367.1 - 0.00059 20.3 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 GAM19367.1 - 0.00087 19.1 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 GAM19367.1 - 0.0015 18.9 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 GAM19367.1 - 0.002 18.0 6.5 0.41 10.4 0.3 3.2 2 1 1 3 3 3 2 AAA domain DEAD PF00270.29 GAM19367.1 - 0.0037 17.0 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 GAM19367.1 - 0.0084 15.6 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_5 PF07728.14 GAM19367.1 - 0.015 15.3 0.1 0.069 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAM19367.1 - 0.02 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 GAM19367.1 - 0.021 14.7 0.1 0.07 13.0 0.1 1.9 1 1 0 1 1 1 0 Helicase Viral_helicase1 PF01443.18 GAM19367.1 - 0.03 14.0 3.5 0.34 10.6 0.0 3.1 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase Microtub_bd PF16796.5 GAM19367.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Microtubule binding SH3_13 PF18335.1 GAM19367.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Zeta_toxin PF06414.12 GAM19367.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 GAM19367.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 GAM19367.1 - 0.11 12.5 0.0 2.4 8.0 0.0 2.8 3 0 0 3 3 3 0 NTPase TsaE PF02367.17 GAM19367.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 GAM19367.1 - 0.14 12.1 0.0 0.38 10.6 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Draxin PF15550.6 GAM19367.1 - 2.1 8.1 5.8 3.8 7.3 5.8 1.3 1 0 0 1 1 1 0 Draxin Iso_dh PF00180.20 GAM19368.1 - 4.8e-77 259.5 0.0 5.7e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SET PF00856.28 GAM19369.1 - 3.7e-13 50.2 0.1 1.4e-12 48.4 0.1 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 GAM19369.1 - 1.9e-08 34.2 14.7 1.9e-08 34.2 14.7 2.7 2 1 0 2 2 2 1 MYND finger Corona_NS2 PF04753.12 GAM19369.1 - 0.059 13.9 0.3 0.11 13.0 0.3 1.4 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 SET PF00856.28 GAM19370.1 - 5.4e-14 52.9 0.1 1.3e-13 51.7 0.1 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 GAM19370.1 - 1.1e-08 35.0 12.1 1.1e-08 35.0 12.1 3.3 4 1 0 4 4 4 1 MYND finger PI-PLC-C1 PF16670.5 GAM19370.1 - 0.0057 15.8 0.2 0.01 15.0 0.0 1.5 2 0 0 2 2 2 1 Phosphoinositide phospholipase C, Ca2+-dependent Phage_Arf PF17585.2 GAM19370.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Accessory recombination function protein Hema_stalk PF08720.10 GAM19370.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk ArfGap PF01412.18 GAM19371.1 - 9.8e-29 99.8 0.4 9.8e-29 99.8 0.4 3.0 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf zf-B_box PF00643.24 GAM19371.1 - 0.0077 16.4 2.7 0.013 15.6 2.7 1.3 1 0 0 1 1 1 1 B-box zinc finger Myotub-related PF06602.14 GAM19372.1 - 3.8e-129 430.6 0.0 9.4e-129 429.3 0.0 1.6 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ank_4 PF13637.6 GAM19372.1 - 3.7e-21 75.2 3.0 1.1e-07 32.2 0.0 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM19372.1 - 1.3e-19 70.6 5.9 1.5e-07 31.9 1.7 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAM19372.1 - 8.7e-17 60.7 2.1 0.0079 16.6 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GAM19372.1 - 3.7e-16 59.0 0.1 8.6e-07 29.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19372.1 - 1.4e-13 49.7 4.1 0.081 13.5 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat GRAM PF02893.20 GAM19372.1 - 8.3e-06 25.7 0.1 0.00041 20.2 0.0 2.5 2 0 0 2 2 2 1 GRAM domain DUF3447 PF11929.8 GAM19372.1 - 0.03 14.3 2.0 2.5 8.1 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Y_phosphatase3 PF13350.6 GAM19372.1 - 0.032 14.2 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 GAM19372.1 - 0.066 13.0 0.0 0.25 11.1 0.0 2.0 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Pkinase PF00069.25 GAM19373.1 - 3.6e-73 246.2 0.0 4.6e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19373.1 - 1.4e-32 113.0 0.0 2.5e-32 112.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM19373.1 - 6.4e-07 29.0 0.0 8e-05 22.1 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 GAM19373.1 - 0.04 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family AMP-binding PF00501.28 GAM19374.1 - 1.3e-90 304.0 0.0 2e-90 303.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.25 GAM19375.1 - 1.2e-61 208.4 0.1 2.4e-61 207.4 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19375.1 - 2.7e-47 161.2 0.1 4.6e-47 160.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM19375.1 - 2.3e-05 23.4 0.0 8e-05 21.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase SH3_1 PF00018.28 GAM19375.1 - 2.4e-05 23.8 0.0 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM19375.1 - 0.00014 21.5 0.0 0.00055 19.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 GAM19375.1 - 0.0022 17.8 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain RIO1 PF01163.22 GAM19375.1 - 0.0034 17.0 1.5 0.0045 16.6 0.1 1.9 2 1 0 2 2 2 1 RIO1 family APH PF01636.23 GAM19375.1 - 0.0072 16.3 0.0 0.29 11.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAM19375.1 - 0.019 14.3 0.1 0.087 12.1 0.0 2.1 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.14 GAM19375.1 - 0.026 13.9 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAM19375.1 - 0.059 13.0 4.5 0.26 10.9 0.1 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Med3 PF11593.8 GAM19375.1 - 2.5 7.2 17.2 6.6 5.8 16.7 1.6 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Coiled PF05710.12 GAM19376.1 - 0.0024 18.7 9.3 0.0029 18.4 9.3 1.1 1 0 0 1 1 1 1 Coiled coil Bac_surface_Ag PF01103.23 GAM19377.1 - 4.9e-09 36.1 9.2 7.8e-09 35.5 9.2 1.3 1 1 0 1 1 1 1 Surface antigen Syja_N PF02383.18 GAM19378.1 - 4.1e-82 276.0 0.0 6.1e-82 275.5 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain NOA36 PF06524.12 GAM19378.1 - 0.66 9.2 4.9 1.3 8.2 4.9 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GAM19378.1 - 8.4 6.9 15.1 25 5.3 15.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RB_A PF01858.17 GAM19379.1 - 3e-32 112.1 0.1 3e-32 112.1 0.1 3.9 4 0 0 4 4 4 1 Retinoblastoma-associated protein A domain DUF3452 PF11934.8 GAM19379.1 - 1.8e-22 79.4 0.0 1.8e-22 79.4 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3452) RB_B PF01857.20 GAM19379.1 - 2e-14 53.7 5.0 2.1e-12 47.2 5.0 3.1 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF2228 PF10228.9 GAM19379.1 - 0.3 10.8 1.7 1 9.1 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2228) Methyltransf_25 PF13649.6 GAM19380.1 - 2.4e-18 66.6 0.0 5.8e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM19380.1 - 7.6e-18 64.9 0.0 1.6e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM19380.1 - 7.8e-16 58.2 0.0 1.1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM19380.1 - 8.6e-16 58.0 0.0 3.7e-15 55.9 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAM19380.1 - 2.7e-10 40.3 0.0 3.7e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM19380.1 - 9e-09 36.0 0.0 1.4e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 GAM19380.1 - 2.1e-07 30.5 0.0 3.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 GAM19380.1 - 4.3e-06 26.4 0.0 9e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 GAM19380.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MetW PF07021.12 GAM19380.1 - 0.0039 16.8 0.1 0.02 14.5 0.1 2.0 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 GAM19380.1 - 0.0095 15.7 0.0 0.016 15.0 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 GAM19380.1 - 0.016 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 GAM19380.1 - 0.022 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) CMAS PF02353.20 GAM19380.1 - 0.023 14.0 0.0 0.11 11.8 0.0 1.9 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 GAM19380.1 - 0.045 13.9 0.1 6.7 6.8 0.0 2.2 1 1 1 2 2 2 0 FtsJ-like methyltransferase ADH_zinc_N PF00107.26 GAM19380.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_32 PF13679.6 GAM19380.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 GAM19380.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RrnaAD PF00398.20 GAM19380.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 GAM19380.1 - 0.17 11.3 0.0 0.48 9.9 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase GCV_T PF01571.21 GAM19383.1 - 0.0014 18.0 0.1 0.003 17.0 0.1 1.5 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain Pkinase PF00069.25 GAM19384.1 - 6.7e-58 196.1 0.0 1e-57 195.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19384.1 - 2.7e-44 151.4 0.0 4e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM19384.1 - 0.00016 20.6 0.2 0.00043 19.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 GAM19384.1 - 0.027 14.1 0.0 7.2 6.2 0.0 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-CCHC PF00098.23 GAM19385.1 - 6.2e-19 67.1 34.5 2.8e-06 27.1 2.8 4.4 4 0 0 4 4 4 4 Zinc knuckle CMS1 PF14617.6 GAM19385.1 - 2e-13 50.2 10.9 4.9e-12 45.7 11.3 2.7 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit zf-CCHC_4 PF14392.6 GAM19385.1 - 0.00029 20.5 21.1 0.3 10.8 1.0 4.4 4 0 0 4 4 4 3 Zinc knuckle DEAD PF00270.29 GAM19385.1 - 0.015 15.0 0.1 0.031 14.1 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase zf-CCHC_6 PF15288.6 GAM19385.1 - 1.5 8.7 25.6 0.25 11.2 0.6 4.4 2 2 2 4 4 4 0 Zinc knuckle Menin PF05053.13 GAM19385.1 - 5.5 5.2 13.7 8.5 4.6 13.7 1.4 1 0 0 1 1 1 0 Menin zf-RING_2 PF13639.6 GAM19386.1 - 1.3e-12 47.9 4.1 2.5e-12 46.9 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAM19386.1 - 5.4e-10 38.8 3.9 1e-09 38.0 3.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAM19386.1 - 6.6e-10 39.1 1.8 2e-09 37.6 1.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAM19386.1 - 5.9e-08 32.4 3.6 1.2e-07 31.5 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM19386.1 - 4.2e-07 29.7 4.6 9.4e-07 28.6 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAM19386.1 - 1.8e-06 27.5 1.9 3.3e-06 26.6 1.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAM19386.1 - 1.2e-05 25.3 0.4 2.6e-05 24.2 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAM19386.1 - 1.6e-05 24.8 3.7 3.7e-05 23.7 3.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAM19386.1 - 2.2e-05 24.3 2.2 4.3e-05 23.4 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 GAM19386.1 - 0.00082 19.1 0.7 0.0026 17.6 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 GAM19386.1 - 0.0019 18.4 2.8 0.0039 17.3 2.8 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 GAM19386.1 - 0.0056 16.8 4.6 0.011 15.9 4.6 1.5 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_3 PF13920.6 GAM19386.1 - 0.0068 16.2 5.1 0.012 15.5 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 GAM19386.1 - 0.017 15.0 0.1 0.05 13.5 0.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 GAM19386.1 - 0.022 15.1 1.0 0.057 13.7 1.0 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 GAM19386.1 - 0.053 13.6 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 GAM19386.1 - 0.094 12.6 2.1 0.22 11.4 2.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 GAM19386.1 - 1.9 8.4 5.9 3.7 7.5 5.9 1.5 1 0 0 1 1 1 0 PHD-finger Pap_E4 PF02711.14 GAM19386.1 - 2.5 9.1 6.3 37 5.4 4.0 2.6 2 0 0 2 2 2 0 E4 protein zf-C3HC4_4 PF15227.6 GAM19386.1 - 6.2 7.1 8.4 67 3.8 8.5 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Gelsolin PF00626.22 GAM19387.1 - 0.00039 20.3 0.0 0.00053 19.8 0.0 1.2 1 0 0 1 1 1 1 Gelsolin repeat Sec23_trunk PF04811.15 GAM19388.1 - 2.8e-13 50.0 0.5 1e-12 48.1 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GAM19388.1 - 6.2e-10 39.7 0.3 5.1e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAM19388.1 - 7.1e-10 38.8 3.8 1.5e-09 37.7 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 GAM19388.1 - 0.022 14.2 0.0 0.078 12.4 0.0 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FYVE_2 PF02318.16 GAM19388.1 - 0.024 14.9 0.1 0.065 13.5 0.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger zinc_ribbon_10 PF10058.9 GAM19388.1 - 6 6.7 5.6 14 5.5 5.6 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Palm_thioest PF02089.15 GAM19389.1 - 1.5e-86 290.2 0.0 1.7e-86 290.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 GAM19389.1 - 0.0041 16.8 0.0 0.0099 15.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_2 PF01674.18 GAM19389.1 - 0.011 15.3 0.0 0.047 13.2 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 2) RasGEF PF00617.19 GAM19390.1 - 1.5e-49 168.6 0.9 2.1e-48 164.9 0.2 2.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM19390.1 - 0.0063 16.7 2.3 0.099 12.9 2.3 3.0 1 1 0 1 1 1 1 RasGEF N-terminal motif GCFC PF07842.12 GAM19391.1 - 2.2e-20 73.4 4.7 1.2e-17 64.4 4.7 3.4 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein DUF1664 PF07889.12 GAM19391.1 - 3.2 7.8 6.5 8.7 6.4 0.2 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) LysM PF01476.20 GAM19392.1 - 1.3e-05 25.2 0.0 3.2e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.6 GAM19392.1 - 0.00026 20.7 0.0 0.0007 19.4 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain DUF4718 PF15842.5 GAM19392.1 - 3.2 7.5 8.0 0.69 9.7 4.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4718) TMEM214 PF10151.9 GAM19393.1 - 4.7 5.6 11.5 5.5 5.3 11.5 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator HHH_3 PF12836.7 GAM19394.1 - 6.7e-08 32.7 0.0 1.1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF655 PF04919.12 GAM19394.1 - 0.00032 20.7 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.6 GAM19394.1 - 0.007 16.6 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 GAM19394.1 - 0.03 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Methyltransf_11 PF08241.12 GAM19396.1 - 4.6e-20 72.1 0.0 8.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM19396.1 - 8.8e-19 68.0 0.0 1.8e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM19396.1 - 1.1e-16 60.8 0.0 6.9e-16 58.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAM19396.1 - 4.7e-11 42.7 0.0 7.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM19396.1 - 3.1e-10 40.7 0.0 5.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM19396.1 - 1.2e-09 38.2 0.0 1.6e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM19396.1 - 0.032 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 GAM19396.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 GAM19396.1 - 0.06 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase FAD_binding_3 PF01494.19 GAM19397.1 - 9.5e-87 291.5 0.0 1.3e-86 291.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAM19397.1 - 1e-07 31.9 0.2 4.3e-06 26.5 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM19397.1 - 2.8e-06 27.5 0.0 6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM19397.1 - 2.5e-05 23.6 0.4 8.3e-05 21.8 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM19397.1 - 0.00089 18.6 0.0 0.037 13.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAM19397.1 - 0.007 16.6 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.6 GAM19397.1 - 0.01 15.1 0.1 0.029 13.6 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM19397.1 - 0.058 12.7 0.3 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAM19397.1 - 0.068 12.4 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 GAM19397.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.6 GAM19397.1 - 0.092 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 GAM19397.1 - 0.13 11.3 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 GAM19397.1 - 0.13 12.8 0.0 0.34 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NTF2 PF02136.20 GAM19398.1 - 2.2e-22 79.9 0.0 2.4e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 GAM19398.1 - 0.0058 16.6 0.0 0.0066 16.4 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Iso_dh PF00180.20 GAM19399.1 - 3.2e-58 197.5 0.1 5.4e-58 196.8 0.1 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AstE_AspA PF04952.14 GAM19400.1 - 2.1e-44 151.7 0.0 1.8e-43 148.7 0.0 1.9 1 1 1 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family PreAtp-grasp PF18604.1 GAM19400.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Pre ATP-grasp domain Peptidase_M14 PF00246.24 GAM19400.1 - 0.16 11.7 1.2 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Zinc carboxypeptidase Hist_deacetyl PF00850.19 GAM19401.1 - 1.6e-72 244.6 3.3 2e-72 244.3 0.1 2.3 2 0 0 2 2 2 1 Histone deacetylase domain zf-4CXXC_R1 PF10497.9 GAM19401.1 - 3.1 8.1 6.9 8.7 6.6 6.9 1.8 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 NT-C2 PF10358.9 GAM19402.1 - 1.9e-24 86.0 3.6 6.1e-24 84.4 3.6 2.0 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.19 GAM19402.1 - 9.4e-22 77.3 0.3 9.4e-22 77.3 0.3 3.5 2 1 2 4 4 4 1 DIL domain DUF5082 PF16888.5 GAM19402.1 - 5.7e-06 26.6 18.9 5.7e-06 26.6 18.9 8.7 3 2 3 6 6 5 1 Domain of unknown function (DUF5082) Filament PF00038.21 GAM19402.1 - 6.5e-05 22.7 124.3 0.00045 19.9 43.3 5.7 1 1 3 4 4 4 3 Intermediate filament protein FAM184 PF15665.5 GAM19402.1 - 0.0013 18.6 39.8 0.0013 18.6 39.8 5.5 1 1 4 5 5 5 1 Family with sequence similarity 184, A and B FliJ PF02050.16 GAM19402.1 - 0.0024 18.1 12.0 0.0024 18.1 12.0 8.3 1 1 4 7 7 5 1 Flagellar FliJ protein TPR_MLP1_2 PF07926.12 GAM19402.1 - 0.0061 16.6 143.2 0.0066 16.5 19.7 9.4 1 1 2 6 6 6 3 TPR/MLP1/MLP2-like protein GAS PF13851.6 GAM19402.1 - 0.0064 15.9 14.9 0.0064 15.9 14.9 7.6 1 1 8 9 9 7 4 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 GAM19402.1 - 0.0065 16.5 9.2 0.0065 16.5 9.2 8.5 1 1 8 9 9 8 1 Laminin Domain II Fez1 PF06818.15 GAM19402.1 - 0.012 16.1 26.0 0.012 16.1 26.0 6.1 1 1 4 5 5 4 0 Fez1 DUF4407 PF14362.6 GAM19402.1 - 0.38 10.1 115.2 0.12 11.7 19.2 6.3 1 1 5 6 6 6 0 Domain of unknown function (DUF4407) ADIP PF11559.8 GAM19402.1 - 0.96 9.5 140.7 0.36 10.9 9.2 8.8 1 1 7 8 8 7 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 GAM19402.1 - 1.6 7.6 142.4 0.042 12.7 19.9 7.6 1 1 5 7 7 6 0 Spc7 kinetochore protein HCO3_cotransp PF00955.21 GAM19402.1 - 2.1 7.1 6.9 0.34 9.7 0.1 2.8 2 0 0 2 2 2 0 HCO3- transporter family Golgin_A5 PF09787.9 GAM19402.1 - 3.2 7.1 142.0 3.4 7.1 19.7 6.1 1 1 5 6 6 6 0 Golgin subfamily A member 5 ATG16 PF08614.11 GAM19402.1 - 5.2 7.2 141.0 0.59 10.3 15.2 7.3 1 1 5 7 7 6 0 Autophagy protein 16 (ATG16) Surfac_D-trimer PF09006.11 GAM19402.1 - 6 6.8 7.5 33 4.5 0.1 5.3 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation ACOX PF01756.19 GAM19403.1 - 3e-20 72.5 0.0 3.6e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA oxidase NAD_binding_11 PF14833.6 GAM19403.1 - 0.064 13.5 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF966 PF06136.13 GAM19403.1 - 0.18 11.5 0.1 0.25 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Acyl-CoA_dh_M PF02770.19 GAM19404.1 - 7.1e-16 58.2 0.0 2.8e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAM19404.1 - 8e-06 26.1 0.0 2.4e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 GAM19404.1 - 0.016 15.7 0.4 0.035 14.6 0.1 1.8 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal MBOAT PF03062.19 GAM19405.1 - 1.8e-24 86.7 25.6 2.8e-24 86.1 25.6 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Presenilin PF01080.17 GAM19405.1 - 0.0029 16.4 0.1 0.011 14.6 0.0 2.0 2 1 0 2 2 2 1 Presenilin MBOAT_2 PF13813.6 GAM19405.1 - 0.0043 17.3 9.3 0.012 15.9 9.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF3552 PF12072.8 GAM19405.1 - 1.7 8.0 9.0 2.7 7.4 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Macoilin PF09726.9 GAM19405.1 - 1.9 6.9 15.5 2.7 6.4 15.5 1.1 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 GAM19405.1 - 3.2 7.1 14.0 7.1 6.0 14.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ank_4 PF13637.6 GAM19406.1 - 2.9e-06 27.7 2.5 0.15 12.7 0.0 6.8 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM19406.1 - 1.1e-05 26.0 10.9 0.0062 17.1 0.0 7.2 8 1 0 10 10 10 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM19406.1 - 0.028 14.7 3.7 57 4.2 0.0 6.6 7 1 1 8 8 8 0 Ankyrin repeats (many copies) LIM PF00412.22 GAM19407.1 - 4.5e-24 84.4 21.7 4.2e-13 49.3 4.6 3.1 3 0 0 3 3 3 2 LIM domain zinc-ribbons_6 PF07191.12 GAM19407.1 - 0.03 14.3 12.7 1.4 8.9 6.4 3.0 1 1 1 2 2 2 0 zinc-ribbons PHF5 PF03660.14 GAM19407.1 - 1.7 8.9 8.4 0.29 11.3 3.7 2.1 1 1 1 2 2 2 0 PHF5-like protein DZR PF12773.7 GAM19407.1 - 2.7 8.1 19.1 7.4 6.7 5.8 3.7 1 1 1 2 2 2 0 Double zinc ribbon PRK PF00485.18 GAM19408.1 - 1.1e-16 61.2 3.1 1e-14 54.8 3.1 2.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.21 GAM19408.1 - 2.1e-13 50.6 0.0 4.8e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 CYTH domain AAA_18 PF13238.6 GAM19408.1 - 6.7e-06 26.7 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAM19408.1 - 0.00096 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TsaE PF02367.17 GAM19408.1 - 0.011 15.7 0.2 0.32 11.0 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 GAM19408.1 - 0.019 14.9 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 GAM19408.1 - 0.028 14.9 0.0 0.086 13.4 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 GAM19408.1 - 0.037 13.7 1.5 0.039 13.7 0.1 1.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAM19408.1 - 0.068 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 GAM19408.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GST_N PF02798.20 GAM19409.1 - 8.8e-12 45.2 0.1 1.7e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM19409.1 - 4.2e-11 42.9 0.4 7.8e-11 42.1 0.4 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM19409.1 - 9.5e-11 42.0 0.0 1.7e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM19409.1 - 1.2e-10 41.4 0.0 2.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM19409.1 - 2.7e-10 40.4 0.0 4.7e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM19409.1 - 1.1e-07 31.8 0.0 2.6e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 GAM19409.1 - 0.028 14.2 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain RasGEF PF00617.19 GAM19410.1 - 1.9e-52 178.0 0.3 4e-52 177.0 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM19410.1 - 2.9e-20 72.5 0.4 8.1e-20 71.0 0.4 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Spc7 PF08317.11 GAM19410.1 - 0.06 12.2 1.0 0.1 11.5 1.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 GAM19410.1 - 0.097 13.1 4.6 0.044 14.2 1.5 2.1 2 0 0 2 2 2 0 Cell division protein ZapB UPF0242 PF06785.11 GAM19410.1 - 0.19 11.8 4.1 8.9 6.4 0.7 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 GAM19410.1 - 0.8 9.5 9.0 0.05 13.4 1.6 2.9 3 0 0 3 3 3 0 Septum formation initiator GSH_synth_ATP PF03917.17 GAM19411.1 - 1e-126 422.7 0.1 1.2e-126 422.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 GAM19411.1 - 1.3e-34 118.7 0.1 9e-34 116.0 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic glutathione synthase zf-B_box PF00643.24 GAM19412.1 - 2.3e-05 24.4 5.2 2.3e-05 24.4 5.2 1.6 2 0 0 2 2 2 1 B-box zinc finger Baculo_PEP_C PF04513.12 GAM19412.1 - 0.068 13.2 2.6 0.058 13.4 0.7 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Colipase-like PF15083.6 GAM19412.1 - 0.079 13.1 3.8 0.2 11.8 3.4 1.9 1 1 0 1 1 1 0 Colipase-like Apolipoprotein PF01442.18 GAM19412.1 - 0.1 12.4 0.3 0.1 12.4 0.3 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain ZNRF_3_ecto PF18212.1 GAM19412.1 - 0.11 12.5 1.6 0.96 9.5 0.1 2.8 2 1 1 3 3 3 0 ZNRF-3 Ectodomain MetOD2 PF18548.1 GAM19412.1 - 0.15 12.2 2.4 0.22 11.7 0.4 2.1 2 0 0 2 2 2 0 Metanogen output domain 2 Swi5 PF07061.11 GAM19412.1 - 1.8 8.7 5.5 2.1 8.5 1.6 2.5 2 0 0 2 2 2 0 Swi5 FOXP-CC PF16159.5 GAM19412.1 - 2.8 8.6 7.5 2.5 8.8 3.3 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-B_box PF00643.24 GAM19413.1 - 6.9e-09 35.7 1.1 1.8e-08 34.4 1.1 1.7 1 0 0 1 1 1 1 B-box zinc finger zf-B_box PF00643.24 GAM19414.1 - 9.4e-10 38.5 3.6 1.7e-09 37.7 3.6 1.4 1 0 0 1 1 1 1 B-box zinc finger Kelch_6 PF13964.6 GAM19414.1 - 4.6e-09 36.2 6.9 0.00038 20.6 0.0 5.2 7 0 0 7 7 7 2 Kelch motif Kelch_4 PF13418.6 GAM19414.1 - 2.1e-05 24.5 4.4 0.032 14.2 0.1 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM19414.1 - 0.00057 19.4 9.1 0.13 11.9 0.1 4.7 4 2 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 GAM19414.1 - 0.15 12.0 5.8 5.7 7.1 0.8 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.6 GAM19414.1 - 0.6 10.5 7.6 6.7 7.1 0.0 4.3 4 1 0 4 4 4 0 Galactose oxidase, central domain Hydrolase_4 PF12146.8 GAM19415.1 - 6.3e-19 68.2 0.0 1.3e-18 67.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM19415.1 - 8.9e-18 64.9 0.9 8.9e-14 51.7 0.2 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM19415.1 - 2.9e-16 60.7 0.0 4e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 GAM19415.1 - 1.2e-06 28.3 0.1 0.0019 17.8 0.0 3.0 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 GAM19415.1 - 3.6e-05 23.6 0.0 0.1 12.4 0.0 2.9 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GAM19415.1 - 0.00026 20.9 0.1 0.021 14.6 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase UPF0227 PF05728.12 GAM19415.1 - 0.0005 20.1 0.0 0.096 12.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Ndr PF03096.14 GAM19415.1 - 0.001 17.8 0.0 0.0062 15.3 0.0 2.0 2 0 0 2 2 2 1 Ndr family Esterase PF00756.20 GAM19415.1 - 0.013 15.2 0.0 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative esterase LIP PF03583.14 GAM19415.1 - 0.013 14.9 0.9 1.1 8.5 0.1 2.5 2 1 0 2 2 2 0 Secretory lipase FSH1 PF03959.13 GAM19415.1 - 0.018 14.7 0.2 0.12 12.0 0.2 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 GAM19415.1 - 0.021 14.5 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 GAM19415.1 - 0.11 12.5 0.0 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain DUF915 PF06028.11 GAM19415.1 - 0.13 11.5 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) CTNNBL PF08216.11 GAM19417.1 - 7.1e-35 119.3 4.4 1.5e-34 118.3 0.1 3.3 2 1 1 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear DUF4704 PF15787.5 GAM19417.1 - 0.063 12.5 4.6 0.4 9.9 0.5 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4704) WTX PF09422.10 GAM19417.1 - 0.11 11.6 0.4 0.17 10.9 0.4 1.2 1 0 0 1 1 1 0 WTX protein Myb_DNA-binding PF00249.31 GAM19418.1 - 1.4e-31 108.4 12.5 2.3e-14 53.3 0.7 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM19418.1 - 5e-27 93.9 7.0 1.1e-14 54.4 0.2 3.5 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 GAM19418.1 - 0.00018 21.5 2.1 0.49 10.4 0.0 3.2 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 GAM19418.1 - 0.0031 17.9 12.7 0.065 13.6 1.0 3.7 2 1 1 3 3 3 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAM19418.1 - 0.0051 17.0 0.5 2.7 8.2 0.0 3.2 2 1 0 2 2 2 2 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 GAM19418.1 - 0.13 12.6 8.3 2.7 8.4 0.1 4.0 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Tsg PF04668.12 GAM19418.1 - 0.34 11.6 5.0 1.1 10.0 0.1 3.0 3 0 0 3 3 3 0 Twisted gastrulation (Tsg) protein conserved region Pkinase PF00069.25 GAM19419.1 - 4.3e-70 236.1 0.3 1.2e-69 234.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19419.1 - 2.1e-55 187.8 0.0 3.4e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM19419.1 - 8.6e-06 24.8 0.0 8.6e-06 24.8 0.0 2.6 2 2 1 3 3 2 1 Fungal protein kinase Kinase-like PF14531.6 GAM19419.1 - 4.3e-05 23.0 0.0 0.00015 21.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PBD PF00786.28 GAM19419.1 - 0.00021 21.6 0.3 0.00057 20.2 0.3 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain MscS_porin PF12795.7 GAM19419.1 - 0.016 14.7 1.2 0.03 13.9 1.2 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain RIO1 PF01163.22 GAM19419.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family ABC1 PF03109.16 GAM19419.1 - 0.062 13.5 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 ABC1 family DUF5082 PF16888.5 GAM19419.1 - 0.16 12.3 5.1 2.7 8.3 2.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Tup_N PF08581.10 GAM19419.1 - 0.17 12.2 1.0 0.42 11.0 1.0 1.6 1 0 0 1 1 1 0 Tup N-terminal Prefoldin_2 PF01920.20 GAM19419.1 - 0.2 11.6 3.4 0.33 10.9 1.9 2.1 2 0 0 2 2 2 0 Prefoldin subunit Kdo PF06293.14 GAM19419.1 - 0.25 10.7 0.4 0.66 9.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM19419.1 - 0.26 11.2 0.0 1.2 9.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1690 PF07956.11 GAM19419.1 - 1.1 9.7 7.1 0.61 10.5 0.7 3.1 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) FlaC_arch PF05377.11 GAM19419.1 - 2.2 8.7 5.4 4 7.9 2.8 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 GAM19420.1 - 0.0013 19.2 0.1 0.0015 19.0 0.1 1.1 1 0 0 1 1 1 1 Fez1 EP400_N PF15790.5 GAM19420.1 - 0.015 14.2 0.6 0.016 14.0 0.6 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal MIF4G_like_2 PF09090.11 GAM19420.1 - 0.11 12.0 1.9 0.13 11.7 1.9 1.1 1 0 0 1 1 1 0 MIF4G like V_ATPase_I PF01496.19 GAM19420.1 - 0.15 10.0 0.4 0.14 10.1 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ly49 PF08391.10 GAM19420.1 - 0.17 12.2 0.9 0.24 11.8 0.9 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region zf-LYAR PF08790.11 GAM19421.1 - 6e-06 26.1 0.2 1.7e-05 24.6 0.2 1.9 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger DDE_Tnp_1_7 PF13843.6 GAM19424.1 - 8.6e-16 58.2 0.4 1.4e-15 57.5 0.4 1.3 1 0 0 1 1 1 1 Transposase IS4 Tub_N PF16322.5 GAM19424.1 - 0.0021 18.5 5.7 0.0021 18.5 5.7 2.3 2 0 0 2 2 2 1 Tubby N-terminal Mpp10 PF04006.12 GAM19424.1 - 0.0092 14.5 32.8 0.078 11.4 12.4 2.1 2 0 0 2 2 2 2 Mpp10 protein CDC45 PF02724.14 GAM19424.1 - 0.014 13.8 31.8 0.17 10.2 13.5 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF913 PF06025.12 GAM19424.1 - 0.072 12.1 7.8 0.21 10.5 1.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CNDH2_C PF16858.5 GAM19424.1 - 0.085 12.7 23.5 0.43 10.4 10.0 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SDA1 PF05285.12 GAM19424.1 - 0.17 11.3 41.1 0.38 10.1 11.0 2.2 2 0 0 2 2 2 0 SDA1 TFIIA PF03153.13 GAM19424.1 - 0.53 10.2 34.6 0.47 10.4 4.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Vfa1 PF08432.10 GAM19424.1 - 0.85 9.9 23.7 4.3 7.6 12.9 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Astro_capsid_p PF12226.8 GAM19424.1 - 0.87 8.7 36.2 2 7.5 19.1 2.2 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Nop14 PF04147.12 GAM19424.1 - 1.7 6.8 43.9 1.1 7.4 13.5 2.1 2 0 0 2 2 2 0 Nop14-like family PTPRCAP PF15713.5 GAM19424.1 - 1.8 8.9 32.2 0.074 13.3 10.2 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PNISR PF15996.5 GAM19424.1 - 2.7 8.2 19.1 1 9.6 0.6 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR FAM60A PF15396.6 GAM19424.1 - 3 7.8 10.0 1.8 8.5 4.5 2.4 2 0 0 2 2 2 0 Protein Family FAM60A DUF2457 PF10446.9 GAM19424.1 - 4.6 6.3 55.5 0.074 12.2 15.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nop53 PF07767.11 GAM19424.1 - 9.1 5.5 28.9 0.87 8.9 11.5 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Cnd1 PF12717.7 GAM19425.1 - 2.4e-41 141.5 21.6 7.6e-41 139.8 3.9 6.5 5 2 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 GAM19425.1 - 2.3e-31 108.9 2.2 2.3e-31 108.9 2.2 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 GAM19425.1 - 0.001 19.1 0.1 4.9 7.7 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat YtzH PF14165.6 GAM19425.1 - 0.097 13.1 7.1 2.4 8.6 0.0 5.0 4 1 1 5 5 5 0 YtzH-like protein CAP_N PF01213.19 GAM19426.1 - 0.17 11.3 3.1 0.085 12.3 1.3 1.4 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ank_3 PF13606.6 GAM19428.1 - 0.00054 20.2 0.4 1.1e+02 3.9 0.0 6.7 6 1 1 7 7 7 0 Ankyrin repeat Ank_2 PF12796.7 GAM19428.1 - 0.002 18.7 3.2 86 3.8 0.0 5.4 4 1 1 6 6 6 0 Ankyrin repeats (3 copies) INT_SG_DDX_CT_C PF15300.6 GAM19428.1 - 0.032 14.0 0.0 0.15 11.9 0.0 2.2 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Ribosomal_L27e PF01777.18 GAM19429.1 - 1.6e-28 98.8 6.6 1.6e-28 98.8 6.6 1.5 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 GAM19429.1 - 6.3e-05 22.8 0.1 0.00037 20.3 0.0 2.2 2 0 0 2 2 2 1 KOW motif Asp_protease PF09668.10 GAM19430.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF2428 PF10350.9 GAM19431.1 - 0.034 13.4 1.2 0.23 10.7 0.1 2.2 1 1 1 2 2 2 0 Putative death-receptor fusion protein (DUF2428) ERG2_Sigma1R PF04622.12 GAM19431.1 - 0.039 13.3 0.4 0.19 11.1 0.2 1.9 2 0 0 2 2 2 0 ERG2 and Sigma1 receptor like protein MMACHC PF16690.5 GAM19431.1 - 0.072 12.7 0.2 0.13 11.8 0.1 1.5 2 0 0 2 2 2 0 Methylmalonic aciduria and homocystinuria type C family FWWh PF14922.6 GAM19431.1 - 0.12 12.3 1.8 0.15 12.0 0.3 1.9 2 1 0 2 2 2 0 Protein of unknown function DUF4962 PF16332.5 GAM19432.1 - 0.082 11.4 4.1 0.13 10.7 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) RIFIN PF02009.16 GAM19432.1 - 0.61 9.9 2.2 0.85 9.5 2.2 1.2 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 GAM19432.1 - 0.73 9.7 18.0 1.4 8.8 18.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family TFIIE_beta PF02186.15 GAM19433.1 - 4.8e-11 42.8 0.0 1.8e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 GAM19433.1 - 3.5e-10 39.4 0.1 1e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 OST-HTH PF12872.7 GAM19433.1 - 0.019 14.7 0.0 0.064 13.1 0.0 1.8 2 0 0 2 2 2 0 OST-HTH/LOTUS domain TPR_2 PF07719.17 GAM19434.1 - 3.4e-45 148.5 18.1 3.7e-08 32.9 0.2 10.9 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 GAM19434.1 - 5.3e-45 149.5 14.0 6.6e-10 38.4 0.1 10.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 GAM19434.1 - 2.6e-32 108.3 15.0 0.0001 22.2 0.1 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 GAM19434.1 - 3.6e-27 94.5 16.4 3.8e-06 27.1 0.2 8.6 6 1 3 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.6 GAM19434.1 - 1.6e-24 86.2 0.0 5.1e-09 36.6 0.0 6.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM19434.1 - 3e-23 82.1 11.9 0.00099 19.6 0.0 8.0 4 2 5 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 GAM19434.1 - 1.2e-21 76.1 9.3 1.1e-07 31.4 0.0 8.4 4 1 5 9 9 9 5 TPR repeat ANAPC3 PF12895.7 GAM19434.1 - 3.9e-21 75.1 20.1 9.3e-12 45.0 1.0 5.8 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GAM19434.1 - 6.5e-21 73.2 4.8 0.0048 17.6 0.0 10.1 4 2 7 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAM19434.1 - 3.9e-16 58.2 6.5 0.0055 17.0 0.0 8.1 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAM19434.1 - 2.5e-15 56.0 8.3 1.5 9.6 0.0 10.4 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM19434.1 - 4.4e-11 42.8 0.5 0.0028 17.8 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM19434.1 - 2.8e-10 39.5 10.1 0.43 10.7 0.2 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAM19434.1 - 1.3e-06 28.1 14.8 0.34 10.8 0.0 7.7 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM19434.1 - 2.8e-06 26.9 2.7 0.14 11.5 0.0 4.8 2 2 0 2 2 2 2 MalT-like TPR region Fis1_TPR_C PF14853.6 GAM19434.1 - 2.8e-05 24.1 8.7 0.025 14.6 0.1 6.5 7 1 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat SRP_TPR_like PF17004.5 GAM19434.1 - 0.00011 22.2 5.2 0.25 11.4 0.4 3.6 4 1 0 4 4 3 2 Putative TPR-like repeat TPR_15 PF13429.6 GAM19434.1 - 0.00042 19.6 0.5 20 4.3 0.0 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat DUF2225 PF09986.9 GAM19434.1 - 0.0064 16.2 7.6 0.64 9.7 0.2 3.8 4 1 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2225) Coatomer_E PF04733.14 GAM19434.1 - 0.0098 15.3 1.2 2.4 7.5 0.1 2.7 2 1 0 2 2 2 1 Coatomer epsilon subunit NARP1 PF12569.8 GAM19434.1 - 0.062 12.2 0.1 0.062 12.2 0.1 3.6 4 1 0 4 4 4 0 NMDA receptor-regulated protein 1 AdoMet_dc PF02675.15 GAM19434.1 - 0.22 11.8 1.0 0.63 10.3 0.3 2.1 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase FAT PF02259.23 GAM19434.1 - 1 8.5 12.4 2 7.5 0.0 4.3 3 1 2 5 5 5 0 FAT domain TFIIA PF03153.13 GAM19434.1 - 5.3 6.9 14.9 8.2 6.3 14.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SpoU_methylase PF00588.19 GAM19435.1 - 3.8e-29 101.7 0.0 5.6e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Oxidored_nitro PF00148.19 GAM19435.1 - 0.0061 15.3 0.0 0.011 14.6 0.0 1.5 1 1 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Eapp_C PF10238.9 GAM19436.1 - 3.6e-41 140.7 15.9 3.6e-41 140.7 15.9 2.0 2 0 0 2 2 2 1 E2F-associated phosphoprotein zf-CCCH PF00642.24 GAM19437.1 - 2.7e-09 36.7 1.3 2.7e-09 36.7 1.3 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 GAM19437.1 - 1e-08 34.9 9.1 2e-08 33.9 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM19437.1 - 5e-07 29.6 6.0 1.5e-06 28.2 6.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAM19437.1 - 5.2e-07 29.5 12.9 1e-06 28.6 12.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM19437.1 - 1.9e-06 27.6 11.7 4.1e-06 26.5 11.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 GAM19437.1 - 2.4e-06 27.4 2.4 2.4e-06 27.4 2.4 1.9 2 0 0 2 2 1 1 Zinc finger domain zf-RING_2 PF13639.6 GAM19437.1 - 3.6e-06 27.2 10.6 3.6e-06 27.2 10.6 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 GAM19437.1 - 3.9e-06 26.6 12.6 9.6e-06 25.4 12.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 GAM19437.1 - 1.6e-05 24.6 1.0 1.6e-05 24.6 1.0 2.6 2 0 0 2 2 2 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 GAM19437.1 - 0.00072 19.4 7.9 0.0014 18.4 7.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GAM19437.1 - 0.0084 16.2 5.9 0.0084 16.2 5.9 1.9 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 GAM19437.1 - 0.02 15.0 9.0 0.055 13.6 9.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING POPLD PF08170.12 GAM19437.1 - 0.25 11.7 2.8 0.17 12.2 0.5 1.9 2 0 0 2 2 2 0 POPLD (NUC188) domain zf-P11 PF03854.14 GAM19437.1 - 0.33 10.6 5.5 0.66 9.7 5.5 1.4 1 0 0 1 1 1 0 P-11 zinc finger FNIP PF05725.12 GAM19438.1 - 1.7e-40 136.9 21.7 1.9e-10 40.7 1.0 7.0 4 2 2 7 7 7 6 FNIP Repeat DUF1769 PF08588.10 GAM19438.1 - 0.01 16.0 4.3 2.1 8.6 0.0 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1769) LRR_4 PF12799.7 GAM19438.1 - 0.018 15.5 11.6 1.2 9.7 0.2 4.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF5094 PF17015.5 GAM19439.1 - 0.0005 20.2 0.2 0.00057 20.0 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5094) TFIID_NTD2 PF04494.15 GAM19439.1 - 0.011 16.0 0.3 0.013 15.7 0.3 1.1 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain DUF1981 PF09324.10 GAM19439.1 - 0.036 13.9 0.2 0.057 13.3 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1981) CHASE7 PF17151.4 GAM19439.1 - 0.065 12.8 0.2 0.074 12.6 0.2 1.2 1 0 0 1 1 1 0 Periplasmic sensor domain SRCR PF00530.18 GAM19439.1 - 0.091 13.3 1.3 0.13 12.8 1.3 1.3 1 1 0 1 1 1 0 Scavenger receptor cysteine-rich domain DUF1043 PF06295.12 GAM19439.1 - 0.095 12.7 1.5 0.15 12.1 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) GTP_EFTU PF00009.27 GAM19441.1 - 1.9e-55 187.4 0.0 2.8e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM19441.1 - 1.6e-37 128.2 0.3 7.1e-37 126.1 0.0 2.2 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAM19441.1 - 9.9e-15 54.7 0.3 2.6e-14 53.4 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM19441.1 - 3.8e-05 23.7 0.1 0.00091 19.3 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GAM19441.1 - 0.02 14.8 1.0 0.046 13.6 0.2 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Ank_2 PF12796.7 GAM19442.1 - 3.6e-13 49.9 14.2 0.2 12.3 0.1 10.2 9 2 2 11 11 11 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM19442.1 - 0.00013 22.1 18.4 7.6 7.5 0.0 11.7 14 0 0 14 14 14 1 Ankyrin repeat Ank_4 PF13637.6 GAM19442.1 - 0.0011 19.5 14.3 24 5.7 0.0 9.8 11 2 1 12 12 12 1 Ankyrin repeats (many copies) DUF4806 PF16064.5 GAM19442.1 - 0.024 14.9 0.7 2.2 8.6 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) Ank_5 PF13857.6 GAM19442.1 - 0.046 14.1 10.2 6.6 7.2 0.0 7.1 8 1 1 9 9 9 0 Ankyrin repeats (many copies) Mito_carr PF00153.27 GAM19443.1 - 3.2e-68 225.7 1.9 2.8e-23 81.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein GMC_oxred_N PF00732.19 GAM19444.1 - 0.00034 20.1 0.8 0.088 12.2 0.2 2.4 1 1 1 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAM19444.1 - 0.0042 16.4 2.7 0.011 15.1 2.5 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM19444.1 - 0.0045 16.6 1.7 0.011 15.3 0.5 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM19444.1 - 0.0094 15.0 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM19444.1 - 0.01 15.0 0.3 0.018 14.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAM19444.1 - 0.025 13.8 0.1 0.048 12.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 GAM19444.1 - 0.028 14.6 0.1 0.083 13.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 GAM19444.1 - 0.031 13.9 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 GAM19444.1 - 0.038 12.7 0.2 0.087 11.5 0.2 1.6 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.21 GAM19444.1 - 0.04 13.3 0.2 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.19 GAM19444.1 - 0.042 13.1 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 GAM19444.1 - 0.077 13.6 0.2 0.22 12.1 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Neuraminidase PF18413.1 GAM19444.1 - 0.18 11.4 0.2 0.48 10.1 0.2 1.6 1 0 0 1 1 1 0 Neuraminidase-like domain Myb_DNA-binding PF00249.31 GAM19445.1 - 5.7e-31 106.4 13.9 2.5e-15 56.4 0.4 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM19445.1 - 2.9e-25 88.3 9.8 1.7e-15 57.0 0.6 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 GAM19445.1 - 5.2e-06 26.5 2.9 0.029 14.4 0.1 2.8 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 GAM19445.1 - 0.00035 20.7 6.4 0.21 11.8 0.5 3.5 1 1 2 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 GAM19445.1 - 0.049 13.5 5.3 2.5 8.1 0.1 2.9 3 0 0 3 3 3 0 Myb DNA-binding like MADF_DNA_bdg PF10545.9 GAM19445.1 - 0.054 13.8 4.5 0.5 10.7 0.2 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Spore_III_AB PF09548.10 GAM19445.1 - 0.15 12.1 0.5 0.25 11.4 0.5 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Chal_sti_synt_N PF00195.19 GAM19445.1 - 0.15 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain UQ_con PF00179.26 GAM19447.1 - 5.4e-42 142.8 0.1 1.1e-41 141.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 GAM19447.1 - 1.6e-10 41.6 0.0 3.9e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Prok-E2_B PF14461.6 GAM19447.1 - 0.00023 20.8 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GAM19447.1 - 0.0018 18.1 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 UEV domain Rad60-SLD PF11976.8 GAM19447.1 - 0.017 14.9 1.5 0.038 13.8 1.5 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 GAM19447.1 - 0.061 13.6 0.0 0.36 11.1 0.0 2.3 1 1 1 2 2 2 0 TUG ubiquitin-like domain Patatin PF01734.22 GAM19448.1 - 1e-16 61.7 0.5 2.8e-16 60.3 0.5 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase ALF PF03752.13 GAM19448.1 - 0.059 13.3 0.5 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Short repeats of unknown function RRM_1 PF00076.22 GAM19449.1 - 1.1e-18 66.8 0.1 1.7e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAM19449.1 - 0.017 15.2 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 Pro_isomerase PF00160.21 GAM19450.1 - 2.7e-42 144.7 0.0 4.7e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 GAM19450.1 - 2.1e-14 53.1 0.0 4.2e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM19450.1 - 0.035 14.1 0.1 0.069 13.2 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SURF2 PF05477.11 GAM19451.1 - 3.3e-30 105.5 24.5 4.6e-30 105.1 24.5 1.3 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) BUD22 PF09073.10 GAM19451.1 - 2.9e-05 23.6 45.0 3.5e-05 23.4 45.0 1.2 1 0 0 1 1 1 1 BUD22 DPM3 PF08285.11 GAM19452.1 - 3.8e-31 107.1 0.3 4.2e-31 107.0 0.3 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pkinase PF00069.25 GAM19453.1 - 5.4e-47 160.4 0.0 2.5e-46 158.2 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19453.1 - 8.6e-25 87.5 0.0 1.6e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_pol_Rbc25 PF08292.12 GAM19453.1 - 0.84 9.9 3.8 1.6 9.0 0.6 2.8 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 S_4TM PF18159.1 GAM19454.1 - 0.0067 15.8 0.0 0.017 14.5 0.0 1.8 1 0 0 1 1 1 1 SMODS-associating 4TM effector domain Formyl_trans_N PF00551.19 GAM19454.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Formyl transferase SpoIIIAH PF12685.7 GAM19454.1 - 0.12 12.2 1.2 0.16 11.8 1.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein zf_CCCH_4 PF18345.1 GAM19455.1 - 5.9e-09 35.7 19.5 0.00013 21.9 2.9 3.6 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 GAM19455.1 - 1.6e-05 25.6 7.9 1.6e-05 25.6 7.9 3.9 2 1 2 4 4 4 2 Torus domain zf-CCCH_2 PF14608.6 GAM19455.1 - 2.1e-05 24.8 18.3 0.18 12.3 1.1 3.5 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger Kelch_4 PF13418.6 GAM19455.1 - 0.00017 21.5 0.6 0.82 9.7 0.1 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain zf-CCCH_3 PF15663.5 GAM19455.1 - 0.00027 21.1 7.2 0.00027 21.1 7.2 2.6 2 1 0 2 2 2 1 Zinc-finger containing family zf-CCCH PF00642.24 GAM19455.1 - 0.00061 19.6 15.8 0.014 15.3 0.6 3.4 2 1 1 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_6 PF13964.6 GAM19455.1 - 0.00068 19.8 0.0 0.36 11.2 0.0 3.8 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAM19455.1 - 0.0071 16.3 0.6 0.39 10.8 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 GAM19455.1 - 0.11 12.1 0.1 6.1 6.5 0.0 3.0 3 0 0 3 3 3 0 Kelch motif zf-CCCH_4 PF18044.1 GAM19455.1 - 1.5 8.7 13.0 1 9.3 0.6 3.4 3 0 0 3 3 3 0 CCCH-type zinc finger Kelch_4 PF13418.6 GAM19456.1 - 1.4e-12 47.4 9.5 2e-07 30.9 0.0 5.9 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM19456.1 - 7.9e-12 45.0 2.3 2.4e-05 24.4 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Baculo_PEP_C PF04513.12 GAM19456.1 - 0.00039 20.5 9.7 0.00039 20.5 9.7 1.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_3 PF13415.6 GAM19456.1 - 0.0018 18.5 2.2 0.69 10.3 0.0 5.0 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM19456.1 - 0.0033 17.0 6.1 0.026 14.1 0.0 4.3 4 1 0 4 4 4 1 Kelch motif FliT PF05400.13 GAM19456.1 - 0.016 16.0 0.3 0.043 14.6 0.3 1.6 1 0 0 1 1 1 0 Flagellar protein FliT DUF3461 PF11944.8 GAM19456.1 - 0.046 13.8 0.4 0.046 13.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) Kelch_2 PF07646.15 GAM19456.1 - 0.061 13.3 0.6 21 5.3 0.0 3.7 4 0 0 4 4 4 0 Kelch motif DUF4111 PF13427.6 GAM19456.1 - 0.075 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Kelch_5 PF13854.6 GAM19456.1 - 0.21 11.6 7.5 5.5 7.1 0.2 4.3 4 0 0 4 4 4 0 Kelch motif RPW8 PF05659.11 GAM19456.1 - 0.26 11.0 2.8 3.3 7.4 0.1 2.7 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 GMP_synt_C PF00958.22 GAM19456.1 - 1.6 8.8 5.2 11 6.1 0.8 3.6 1 1 1 3 3 3 0 GMP synthase C terminal domain FlgN PF05130.12 GAM19456.1 - 2.1 8.8 7.1 1.2 9.6 1.2 2.4 1 1 1 2 2 2 0 FlgN protein DUF948 PF06103.11 GAM19456.1 - 2.8 8.3 7.0 3.5 8.0 0.9 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Kelch_6 PF13964.6 GAM19457.1 - 3.1e-16 59.0 3.2 7.6e-06 26.0 0.0 4.8 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM19457.1 - 1.4e-11 44.2 2.7 8.8e-08 32.0 0.0 4.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM19457.1 - 4.5e-10 39.0 0.3 2.7e-05 23.7 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 GAM19457.1 - 2e-07 31.1 3.3 0.014 15.7 0.0 5.1 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM19457.1 - 3.5e-06 26.8 0.4 0.003 17.5 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 GAM19457.1 - 0.00024 21.0 5.5 0.012 15.6 0.1 4.1 4 0 0 4 4 4 1 Kelch motif FSA_C PF10479.9 GAM19457.1 - 0.058 11.5 7.5 0.083 11.0 7.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RPW8 PF05659.11 GAM19457.1 - 0.11 12.2 0.7 0.25 11.0 0.7 1.6 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FlgN PF05130.12 GAM19457.1 - 1.6 9.2 5.3 3.9 8.0 5.1 1.8 1 1 0 1 1 1 0 FlgN protein FNIP PF05725.12 GAM19458.1 - 3.3e-61 203.2 30.0 2.8e-12 46.6 0.1 8.2 7 3 3 10 10 10 8 FNIP Repeat LRR_8 PF13855.6 GAM19458.1 - 1.1 9.1 5.6 14 5.6 0.1 3.8 3 1 0 3 3 3 0 Leucine rich repeat FNIP PF05725.12 GAM19459.1 - 9.1e-12 45.0 10.3 1.1e-05 25.5 0.5 4.5 5 1 0 5 5 5 3 FNIP Repeat DUF3760 PF12586.8 GAM19459.1 - 0.064 13.4 0.5 0.16 12.2 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3760) FNIP PF05725.12 GAM19460.1 - 7.6e-08 32.4 6.3 0.0032 17.6 0.1 4.0 4 0 0 4 4 4 3 FNIP Repeat FNIP PF05725.12 GAM19461.1 - 5.9e-13 48.8 8.0 0.00025 21.1 0.0 5.1 5 0 0 5 5 5 4 FNIP Repeat FNIP PF05725.12 GAM19463.1 - 0.043 14.0 0.2 0.32 11.2 0.0 2.4 1 1 1 2 2 2 0 FNIP Repeat FNIP PF05725.12 GAM19464.1 - 5.6e-11 42.4 6.0 0.011 15.9 0.0 5.5 3 3 2 5 5 5 5 FNIP Repeat FNIP PF05725.12 GAM19465.1 - 9.8e-06 25.6 10.8 0.0095 16.1 0.0 5.4 4 2 1 5 5 5 2 FNIP Repeat FNIP PF05725.12 GAM19466.1 - 0.0081 16.3 0.6 0.0081 16.3 0.6 4.5 2 2 1 3 3 3 1 FNIP Repeat FNIP PF05725.12 GAM19467.1 - 1.7e-07 31.2 7.0 0.045 13.9 0.1 4.3 4 0 0 4 4 4 3 FNIP Repeat FNIP PF05725.12 GAM19468.1 - 2e-08 34.2 20.3 0.0012 19.0 0.1 7.7 6 2 0 7 7 7 4 FNIP Repeat LRR_4 PF12799.7 GAM19468.1 - 1.3 9.5 8.1 1.2 9.6 0.3 4.3 2 2 1 4 4 4 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 GAM19469.1 - 6.6e-06 26.2 8.0 0.022 14.9 0.6 5.9 3 2 1 4 4 4 3 FNIP Repeat FNIP PF05725.12 GAM19470.1 - 5.8e-11 42.4 13.3 0.023 14.8 0.0 7.1 5 1 1 6 6 6 5 FNIP Repeat F-box_5 PF18511.1 GAM19470.1 - 1.8e-06 27.4 0.1 3.3e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 GAM19470.1 - 0.00014 21.7 0.1 0.00041 20.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM19470.1 - 0.039 13.8 1.8 0.048 13.5 0.1 2.1 2 0 0 2 2 2 0 F-box domain FNIP PF05725.12 GAM19471.1 - 3.5e-06 27.1 4.2 0.0011 19.1 0.1 5.1 5 1 0 5 5 5 2 FNIP Repeat RICTOR_N PF14664.6 GAM19472.1 - 6.2e-103 344.7 5.3 1e-102 343.9 5.3 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 GAM19472.1 - 2.4e-32 111.5 0.0 1.6e-31 108.9 0.0 2.5 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 GAM19472.1 - 3.4e-28 97.7 0.3 1.3e-25 89.4 0.0 4.7 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 GAM19472.1 - 3.1e-27 94.4 2.8 2.2e-24 85.2 0.2 5.1 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, middle domain HEAT_2 PF13646.6 GAM19472.1 - 1.3e-06 28.7 0.2 0.068 13.6 0.0 4.0 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 GAM19472.1 - 1.4e-05 25.5 0.0 0.0014 19.1 0.0 3.5 3 1 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 GAM19472.1 - 0.0038 17.4 1.2 10 6.7 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.23 GAM19472.1 - 0.089 12.9 0.1 2.4 8.3 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 GAM19472.1 - 0.13 12.2 0.9 8.9 6.3 0.0 3.1 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central FNIP PF05725.12 GAM19473.1 - 1.5e-49 165.9 38.9 7.5e-12 45.2 0.0 11.2 10 3 2 12 12 12 9 FNIP Repeat Rax2 PF12768.7 GAM19474.1 - 0.0028 17.2 0.0 0.0028 17.2 0.0 3.2 3 1 1 4 4 4 1 Cortical protein marker for cell polarity Podoplanin PF05808.11 GAM19474.1 - 0.021 14.9 0.9 0.056 13.6 0.1 2.3 2 0 0 2 2 2 0 Podoplanin DUF945 PF06097.11 GAM19474.1 - 0.37 9.8 3.5 0.34 10.0 0.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF945) DUF4083 PF13314.6 GAM19474.1 - 3.5 7.7 7.9 0.95 9.5 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Chlam_PMP PF02415.17 GAM19474.1 - 8.5 7.1 37.1 2.6 8.7 0.2 8.1 8 0 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat FNIP PF05725.12 GAM19475.1 - 3.5e-55 183.9 8.5 9.8e-13 48.0 0.0 8.8 3 2 3 9 9 9 8 FNIP Repeat LRR_1 PF00560.33 GAM19475.1 - 0.88 10.4 5.4 37 5.4 0.2 4.7 3 1 0 3 3 3 0 Leucine Rich Repeat Glutaredoxin PF00462.24 GAM19476.1 - 2.9e-20 72.2 0.1 4e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 GAM19476.1 - 0.00028 21.2 0.2 0.00044 20.6 0.2 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 GAM19476.1 - 0.0014 19.0 0.2 0.0019 18.6 0.2 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 GAM19476.1 - 0.005 16.7 0.3 0.0077 16.1 0.3 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 GAM19476.1 - 0.0083 16.1 0.1 0.015 15.4 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.6 GAM19476.1 - 0.02 15.0 0.2 6.3 6.9 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.20 GAM19476.1 - 0.043 13.6 0.2 0.9 9.3 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin PF00085.20 GAM19476.1 - 0.067 13.2 0.0 0.074 13.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_9 PF14595.6 GAM19476.1 - 0.099 12.4 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 GAM19476.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like GST_N_3 PF13417.6 GAM19476.1 - 0.13 12.6 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain FNIP PF05725.12 GAM19477.1 - 8.2e-90 294.8 37.1 1e-11 44.8 0.0 10.3 5 2 10 15 15 15 13 FNIP Repeat GBP PF02263.19 GAM19478.1 - 3.8e-05 23.1 0.0 7.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 GAM19478.1 - 6.8e-05 22.9 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SHNi-TPR PF10516.9 GAM19478.1 - 0.015 14.8 0.4 0.76 9.3 0.0 2.3 2 0 0 2 2 2 0 SHNi-TPR SWIRM PF04433.17 GAM19479.1 - 5e-29 100.5 0.1 1.2e-28 99.3 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 GAM19479.1 - 5.2e-19 68.0 7.4 5.2e-19 68.0 7.4 2.0 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 GAM19479.1 - 7e-12 45.3 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM19479.1 - 7.5e-06 26.1 0.1 2.4e-05 24.5 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HHH_4 PF14490.6 GAM19479.1 - 0.093 12.7 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain DUF35_N PF12172.8 GAM19479.1 - 0.11 12.5 0.3 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DHHC PF01529.20 GAM19480.1 - 6.9e-36 123.3 11.3 6.9e-36 123.3 11.3 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase QueC PF06508.13 GAM19480.1 - 0.29 10.6 0.8 0.44 10.0 0.8 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF2505 PF10698.9 GAM19481.1 - 0.00065 19.8 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) PRELI PF04707.14 GAM19481.1 - 0.0036 17.1 0.3 0.005 16.7 0.3 1.3 1 0 0 1 1 1 1 PRELI-like family ubiquitin PF00240.23 GAM19482.1 - 9.5e-14 50.9 0.0 1.3e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM19482.1 - 6.6e-07 29.1 0.2 1e-06 28.5 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 GAM19482.1 - 0.0018 18.3 0.0 0.0031 17.6 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAM19482.1 - 0.013 16.1 0.0 0.014 16.0 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Aminotran_1_2 PF00155.21 GAM19483.1 - 1.7e-52 178.8 0.0 2e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAM19483.1 - 0.0022 17.3 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 GAM19483.1 - 0.021 13.4 0.0 0.032 12.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAM19483.1 - 0.05 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAM19483.1 - 0.23 10.7 0.0 0.46 9.7 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DSPc PF00782.20 GAM19484.1 - 1.1e-31 109.4 0.0 1.4e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAM19484.1 - 0.0008 19.6 0.0 0.00088 19.4 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 GAM19484.1 - 0.0057 16.3 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PgaPase_1 PF06162.12 GAM19484.1 - 0.11 12.3 0.2 0.24 11.1 0.1 1.5 1 1 0 1 1 1 0 Putative pyroglutamyl peptidase PgaPase_1 UBX PF00789.20 GAM19486.1 - 6.4e-11 42.3 0.1 2e-10 40.7 0.1 1.8 1 0 0 1 1 1 1 UBX domain ubiquitin PF00240.23 GAM19486.1 - 0.0023 17.7 0.1 0.18 11.6 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin family Ubiquitin_2 PF14560.6 GAM19486.1 - 0.0092 16.4 0.1 0.22 12.0 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-like domain Omp_AT PF11557.8 GAM19486.1 - 0.091 11.7 0.6 0.16 10.9 0.6 1.3 1 0 0 1 1 1 0 Solitary outer membrane autotransporter beta-barrel domain RNase_Zc3h12a PF11977.8 GAM19487.1 - 8.1e-27 93.9 0.0 1.7e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain TFIIA PF03153.13 GAM19487.1 - 2 8.3 32.9 0.12 12.4 3.6 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit VASt PF16016.5 GAM19488.1 - 3.5e-07 30.8 5.0 5.2e-07 30.2 0.5 3.0 2 1 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain DUF1451 PF07295.11 GAM19488.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.9 3 0 0 3 3 3 0 Zinc-ribbon containing domain SdrD_B PF17210.3 GAM19489.1 - 3.4e-11 43.4 9.9 6.6e-05 23.1 0.3 3.2 2 1 1 3 3 3 3 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM19489.1 - 0.54 10.6 5.3 8.4 6.7 0.2 3.2 2 1 1 3 3 3 0 Carboxypeptidase regulatory-like domain Ribosomal_S11 PF00411.19 GAM19490.1 - 1.9e-44 150.6 1.1 2.5e-44 150.2 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L18p PF00861.22 GAM19490.1 - 0.074 13.4 0.2 0.11 12.9 0.2 1.2 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Roughex PF06020.11 GAM19492.1 - 0.0018 17.5 7.2 0.0018 17.5 7.2 2.8 4 0 0 4 4 4 1 Drosophila roughex protein Ribosomal_S17 PF00366.20 GAM19493.1 - 1.6e-19 69.8 1.1 2.6e-19 69.1 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 zf-C4H2 PF10146.9 GAM19494.1 - 4.1e-18 66.5 3.3 5.6e-18 66.0 3.3 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein RasGAP_C PF03836.15 GAM19494.1 - 0.0013 18.9 4.5 0.0013 18.9 4.5 2.0 1 1 1 2 2 2 1 RasGAP C-terminus CALCOCO1 PF07888.11 GAM19494.1 - 0.016 14.1 5.1 0.021 13.7 5.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like APG6_N PF17675.1 GAM19494.1 - 0.029 14.9 6.1 0.054 14.0 6.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region CTNNB1_binding PF08347.11 GAM19494.1 - 0.1 12.8 1.0 0.12 12.5 1.0 1.3 1 1 0 1 1 1 0 N-terminal CTNNB1 binding KELK PF15796.5 GAM19494.1 - 0.42 11.1 6.3 0.57 10.7 4.2 2.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HIP1_clath_bdg PF16515.5 GAM19494.1 - 1.6 9.4 8.1 0.19 12.4 1.5 2.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FNIP PF05725.12 GAM19495.1 - 4.8e-37 125.9 19.4 1.5e-13 50.7 1.1 5.3 3 2 1 5 5 5 5 FNIP Repeat Iron_traffic PF04362.14 GAM19495.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Ank_2 PF12796.7 GAM19496.1 - 2.7e-11 43.9 7.5 0.082 13.5 0.0 8.1 6 1 1 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19496.1 - 2.5e-05 24.8 4.7 0.79 10.4 0.1 7.6 7 1 1 8 8 8 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM19496.1 - 0.015 15.6 1.0 85 3.6 0.0 5.8 5 1 0 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19496.1 - 0.016 15.7 13.1 1.8 9.4 0.1 8.5 11 0 0 11 11 11 0 Ankyrin repeat adh_short PF00106.25 GAM19497.1 - 4.4e-50 169.8 0.1 6.1e-50 169.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM19497.1 - 8.1e-37 127.0 0.2 1.3e-36 126.3 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM19497.1 - 3.9e-14 53.0 0.1 6.7e-14 52.2 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAM19497.1 - 1.3e-05 24.8 0.3 6e-05 22.6 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM19497.1 - 6.3e-05 22.9 0.1 9.3e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAM19497.1 - 0.0039 16.3 0.0 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain FliH PF02108.16 GAM19497.1 - 0.02 14.9 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Flagellar assembly protein FliH Mob1_phocein PF03637.17 GAM19498.1 - 1.9e-82 275.3 0.0 2.2e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family PAS_3 PF08447.12 GAM19499.1 - 4.7e-08 33.2 0.0 8.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 GAM19499.1 - 7.5e-06 26.2 0.1 2.5e-05 24.5 0.1 1.9 1 0 0 1 1 1 1 PAS domain Zn_clus PF00172.18 GAM19499.1 - 0.001 19.1 5.9 0.0017 18.4 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1624 PF07786.12 GAM19500.1 - 1.9e-07 30.9 7.6 1.9e-07 30.9 7.6 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 GAM19500.1 - 6.5e-06 25.8 1.1 6.5e-06 25.8 1.1 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF5009) Tim17 PF02466.19 GAM19501.1 - 7e-19 68.2 1.0 1.2e-18 67.5 1.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_9 PF00759.19 GAM19502.1 - 2.3e-101 340.2 20.3 2.3e-101 340.2 20.3 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 Ibs_toxin PF13956.6 GAM19502.1 - 1 9.4 5.5 2.3 8.3 5.5 1.5 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Peptidase_M16 PF00675.20 GAM19503.1 - 6.7e-36 123.5 0.1 1.9e-35 122.0 0.1 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 GAM19503.1 - 1.1e-34 120.1 2.7 2.4e-34 118.9 2.7 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 GAM19503.1 - 1.8e-23 83.5 0.0 2.5e-16 60.2 0.0 4.4 3 2 0 3 3 3 2 Peptidase M16 inactive domain FAD_syn PF06574.12 GAM19503.1 - 0.032 14.1 0.5 4 7.3 0.2 2.8 2 0 0 2 2 2 0 FAD synthetase ETC_C1_NDUFA5 PF04716.14 GAM19503.1 - 0.047 13.5 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 ETC complex I subunit conserved region DUF4287 PF14117.6 GAM19503.1 - 0.16 12.2 0.1 0.72 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) CAP PF00188.26 GAM19504.1 - 5.1e-05 24.1 0.8 9.7e-05 23.2 0.1 1.9 2 1 0 2 2 2 1 Cysteine-rich secretory protein family RhoGAP PF00620.27 GAM19505.1 - 4.5e-30 104.5 0.9 1.6e-29 102.7 0.3 2.1 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 GAM19505.1 - 0.00036 21.0 0.4 0.0047 17.4 0.4 2.5 1 1 0 1 1 1 1 PH domain Pkinase PF00069.25 GAM19506.1 - 2.3e-57 194.4 0.0 3.2e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19506.1 - 3.5e-43 147.7 0.0 5e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM19506.1 - 2.5e-06 27.1 0.0 4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YL1 PF05764.13 GAM19506.1 - 0.00035 20.8 0.4 0.00052 20.2 0.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 GAM19506.1 - 0.0022 16.4 1.8 0.0029 16.0 1.8 1.1 1 0 0 1 1 1 1 CDC45-like protein FTA2 PF13095.6 GAM19506.1 - 0.0096 15.6 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 GAM19506.1 - 0.085 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NUDE_C PF04880.13 GAM19506.1 - 3 8.3 9.9 5.9 7.3 9.9 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region WD40 PF00400.32 GAM19507.1 - 1e-61 203.4 21.3 3.6e-09 37.1 0.7 9.2 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM19507.1 - 3e-23 81.9 4.1 0.00016 21.9 0.0 6.3 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 GAM19507.1 - 9.2e-15 54.9 1.1 1.6e-14 54.2 1.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 GAM19507.1 - 2.6e-10 40.5 0.4 0.0059 16.5 0.0 4.2 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM19507.1 - 6.2e-08 32.0 1.6 0.03 13.3 0.0 4.6 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAM19507.1 - 3.6e-07 29.2 2.2 1.2 7.7 0.0 5.0 4 2 2 6 6 6 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 GAM19507.1 - 2.3e-05 23.9 0.3 0.018 14.4 0.0 4.1 3 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal CHAP PF05257.16 GAM19507.1 - 0.0016 19.0 3.0 5.1 7.7 0.1 4.7 1 1 1 3 3 3 1 CHAP domain WD40_like PF17005.5 GAM19507.1 - 0.0048 16.3 0.0 21 4.3 0.0 3.8 4 0 0 4 4 4 0 WD40-like domain Coatomer_WDAD PF04053.14 GAM19507.1 - 0.034 13.2 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Coatomer WD associated region PQQ PF01011.21 GAM19507.1 - 0.065 13.2 0.1 0.27 11.2 0.1 2.1 1 0 0 1 1 1 0 PQQ enzyme repeat PD40 PF07676.12 GAM19507.1 - 0.15 12.1 3.5 70 3.5 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RhoGEF PF00621.20 GAM19509.1 - 6.1e-46 156.9 2.3 6.1e-46 156.9 2.3 2.5 3 0 0 3 3 3 1 RhoGEF domain PX PF00787.24 GAM19509.1 - 3.2e-18 65.8 0.8 1e-17 64.2 0.8 1.9 1 0 0 1 1 1 1 PX domain CH PF00307.31 GAM19509.1 - 4e-09 36.6 0.1 2e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 GAM19509.1 - 0.0024 17.5 1.4 0.0065 16.2 1.4 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Gemin6 PF06372.12 GAM19509.1 - 0.045 13.3 0.1 0.13 11.8 0.1 1.8 1 0 0 1 1 1 0 Gemin6 protein Tom37 PF10568.9 GAM19509.1 - 0.073 13.4 1.6 0.15 12.4 0.6 2.0 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Trypan_PARP PF05887.11 GAM19509.1 - 2.1 8.3 10.6 4.6 7.2 10.6 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ATG_C PF09333.11 GAM19510.1 - 2.4e-34 117.6 2.0 2.8e-34 117.3 0.5 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 GAM19510.1 - 4.4e-13 49.2 0.4 3.2e-12 46.4 0.0 2.8 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.7 GAM19510.1 - 6.7e-13 48.8 0.0 3e-12 46.7 0.0 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 DUF5542 PF17696.1 GAM19510.1 - 1.2 9.3 5.0 12 6.1 0.0 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5542) SdrD_B PF17210.3 GAM19511.1 - 3.5e-204 664.9 221.3 4e-08 33.5 0.8 30.9 28 3 3 31 31 31 30 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM19511.1 - 1e-37 128.2 163.4 0.074 13.3 0.7 30.7 31 0 0 31 31 31 21 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 GAM19511.1 - 1.9e-30 105.5 33.2 0.77 9.9 0.0 24.6 26 0 0 26 26 26 4 Protein of unknown function (DUF2012) DUF1842 PF08896.10 GAM19511.1 - 9.1e-17 61.4 11.1 5.1 7.4 0.0 14.0 15 0 0 15 15 15 6 Domain of unknown function (DUF1842) SpaA PF17802.1 GAM19511.1 - 2.7e-11 43.6 132.8 2.5 8.5 0.1 27.2 28 2 0 28 28 28 9 Prealbumin-like fold domain Monooxygenase_B PF04744.12 GAM19511.1 - 2e-06 26.9 12.3 18 4.0 0.1 10.3 7 5 5 12 12 12 2 Monooxygenase subunit B protein Ehrlichia_rpt PF09528.10 GAM19511.1 - 3.1e-06 26.5 4.9 3.4 7.2 0.2 9.3 12 0 0 12 12 12 1 Ehrlichia tandem repeat (Ehrlichia_rpt) DUF3875 PF12991.7 GAM19511.1 - 0.0012 18.7 2.5 2e+02 2.0 0.0 7.9 9 0 0 9 9 9 0 Domain of unknown function, B. Theta Gene description (DUF3875) MOSC PF03473.17 GAM19511.1 - 0.0012 18.8 0.0 59 3.7 0.0 7.0 10 0 0 10 10 10 0 MOSC domain SdrD_B PF17210.3 GAM19512.1 - 4.2e-22 78.5 20.0 1.3e-09 38.2 0.3 13.0 5 1 6 12 12 12 4 SdrD B-like domain Csm4_C PF17953.1 GAM19512.1 - 0.051 13.4 0.0 2.5 8.0 0.0 3.4 4 0 0 4 4 4 0 CRISPR Csm4 C-terminal domain Cro PF09048.10 GAM19512.1 - 0.13 12.4 0.0 28 4.8 0.0 3.4 3 0 0 3 3 3 0 Cro UNC-50 PF05216.13 GAM19513.1 - 3.3e-81 272.1 35.9 3.7e-81 271.9 35.9 1.0 1 0 0 1 1 1 1 UNC-50 family DUF1474 PF07342.11 GAM19513.1 - 0.092 13.3 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1474) THUMP PF02926.17 GAM19515.1 - 2.3e-08 34.2 5.5 8.3e-08 32.4 2.8 2.1 2 0 0 2 2 2 1 THUMP domain DUF3949 PF13133.6 GAM19515.1 - 0.14 12.7 0.1 0.37 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3949) BCS1_N PF08740.11 GAM19516.1 - 1.2e-46 159.1 1.1 1.9e-46 158.4 1.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 GAM19516.1 - 2e-15 57.4 0.0 7.6e-14 52.3 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM19516.1 - 0.0003 21.2 0.0 0.0012 19.2 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 GAM19516.1 - 0.0015 17.8 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 GAM19516.1 - 0.014 15.9 0.1 0.052 14.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 GAM19516.1 - 0.021 14.4 0.0 0.099 12.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM19516.1 - 0.028 14.8 0.0 0.1 13.0 0.0 2.1 1 0 0 1 1 1 0 RNA helicase PPV_E1_C PF00519.17 GAM19516.1 - 0.033 13.0 0.0 0.17 10.7 0.0 1.9 2 0 0 2 2 2 0 Papillomavirus helicase AAA_29 PF13555.6 GAM19516.1 - 0.033 13.9 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 GAM19516.1 - 0.035 13.9 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM19516.1 - 0.036 13.6 0.0 0.094 12.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 GAM19516.1 - 0.039 14.1 0.0 0.15 12.2 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_PrkA PF08298.11 GAM19516.1 - 0.047 12.6 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_18 PF13238.6 GAM19516.1 - 0.05 14.2 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAM19516.1 - 0.086 13.1 0.0 0.39 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GAM19516.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 GAM19516.1 - 0.12 12.4 0.1 0.37 10.9 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase RuvB_N PF05496.12 GAM19516.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 GAM19516.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 GAM19516.1 - 0.15 11.2 0.0 0.76 8.9 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain DUF3899 PF13038.6 GAM19516.1 - 0.21 12.1 0.7 0.55 10.8 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Mucin PF01456.17 GAM19517.1 - 5.4 7.0 24.1 0.36 10.8 19.0 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.12 GAM19517.1 - 6.3 4.7 10.2 6.6 4.6 10.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LIM PF00412.22 GAM19518.1 - 0.011 16.0 3.6 0.032 14.5 3.6 1.8 1 0 0 1 1 1 0 LIM domain Cys_rich_KTR PF14205.6 GAM19518.1 - 0.28 11.0 2.3 2.1 8.2 0.8 2.5 2 0 0 2 2 2 0 Cysteine-rich KTR Lar_restr_allev PF14354.6 GAM19518.1 - 0.58 10.6 5.9 0.26 11.7 1.8 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 GAM19518.1 - 4.2 7.5 7.7 13 5.9 5.0 2.7 2 1 0 2 2 2 0 Double zinc ribbon GST_N_2 PF13409.6 GAM19519.1 - 5.7e-17 61.8 0.0 1.8e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM19519.1 - 3.5e-10 39.8 0.0 6.8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM19519.1 - 1.5e-07 31.6 0.0 2.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM19519.1 - 0.0057 16.8 0.1 0.01 16.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM19519.1 - 0.071 13.5 0.1 0.41 11.1 0.1 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Phi_1 PF04674.12 GAM19519.1 - 0.099 11.9 0.0 0.82 8.9 0.0 2.0 2 0 0 2 2 2 0 Phosphate-induced protein 1 conserved region Pkinase_Tyr PF07714.17 GAM19520.1 - 2e-64 217.4 0.0 2.9e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM19520.1 - 3.3e-57 193.9 0.0 4.5e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAM19520.1 - 0.00018 21.5 0.0 0.00038 20.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM19520.1 - 0.0097 14.9 0.1 0.21 10.5 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM19520.1 - 0.022 13.6 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase NICE-3 PF07406.11 GAM19520.1 - 0.06 13.3 0.7 0.24 11.4 0.2 1.9 2 0 0 2 2 2 0 NICE-3 protein Phage_holin_2_1 PF04971.12 GAM19520.1 - 0.1 12.6 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Bacteriophage P21 holin S Pkinase_Tyr PF07714.17 GAM19521.1 - 2.4e-62 210.5 0.0 3.2e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM19521.1 - 1.5e-54 185.2 0.0 2e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAM19521.1 - 0.00061 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM19521.1 - 0.017 13.9 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 GAM19521.1 - 0.045 12.7 0.1 0.22 10.5 0.1 1.8 2 0 0 2 2 2 0 Haspin like kinase domain MGC-24 PF05283.11 GAM19521.1 - 0.49 10.8 10.2 0.076 13.5 6.0 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_hydro_38N PF01074.22 GAM19522.1 - 1e-92 310.6 2.3 1.5e-92 310.0 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAM19522.1 - 8e-33 114.3 0.2 1.4e-32 113.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAM19522.1 - 2e-19 69.5 0.1 4.5e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_57 PF03065.15 GAM19522.1 - 0.0014 17.9 0.0 0.0035 16.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Glyco_hydro38C2 PF17677.1 GAM19522.1 - 0.0032 17.5 0.0 0.0085 16.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain CarboxypepD_reg PF13620.6 GAM19522.1 - 0.057 13.7 1.2 0.22 11.8 1.2 2.0 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Filamin PF00630.19 GAM19523.1 - 4.2e-122 400.1 11.5 2.5e-22 79.6 0.1 6.2 6 0 0 6 6 6 6 Filamin/ABP280 repeat CH PF00307.31 GAM19523.1 - 2.2e-44 150.1 0.6 8e-23 80.7 0.9 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain Invasin_D3 PF09134.10 GAM19523.1 - 1.1e-25 89.8 8.7 0.0043 17.3 0.0 6.3 6 0 0 6 6 6 6 Invasin, domain 3 YtkA PF13115.6 GAM19523.1 - 9e-10 39.0 8.8 0.078 13.6 0.0 6.1 6 0 0 6 6 6 4 YtkA-like Y_Y_Y PF07495.13 GAM19523.1 - 4.6e-09 36.1 2.9 0.36 10.8 0.0 5.7 5 0 0 5 5 5 4 Y_Y_Y domain CAMSAP_CH PF11971.8 GAM19523.1 - 2e-07 30.7 0.1 0.0082 15.9 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain DUF5060 PF16586.5 GAM19523.1 - 1.5e-06 28.5 1.2 3.7 8.0 0.0 5.1 5 0 0 5 5 5 2 Domain of unknown function (DUF5060) Big_6 PF17936.1 GAM19523.1 - 2.6e-05 24.4 17.6 0.82 10.0 0.1 7.1 7 1 0 7 7 7 2 Bacterial Ig domain Big_1 PF02369.16 GAM19523.1 - 0.0015 18.5 10.6 1.3 9.0 0.6 5.8 6 0 0 6 6 6 2 Bacterial Ig-like domain (group 1) Glyco_hydro2_C5 PF18565.1 GAM19523.1 - 0.27 11.1 6.5 8.7 6.3 0.0 4.4 4 0 0 4 4 4 0 Glycoside hydrolase family 2 C-terminal domain 5 Neurexophilin PF06312.12 GAM19523.1 - 0.31 10.5 3.4 81 2.6 0.0 4.5 5 1 1 6 6 6 0 Neurexophilin Cadherin_5 PF17892.1 GAM19523.1 - 0.6 10.1 15.2 2.8 8.0 0.5 5.3 5 0 0 5 5 5 0 Cadherin-like domain zf-RING_2 PF13639.6 GAM19524.1 - 0.002 18.4 7.4 0.002 18.4 7.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 GAM19524.1 - 0.061 13.1 3.8 0.15 11.8 3.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger FH2 PF02181.23 GAM19525.1 - 1.2e-89 301.1 4.0 2e-89 300.3 0.2 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 GAM19525.1 - 3.8e-33 114.8 0.1 3.8e-33 114.8 0.1 2.6 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 GAM19525.1 - 7.3e-33 113.7 0.3 2.5e-32 112.0 0.3 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain SlyX PF04102.12 GAM19525.1 - 2.2e-06 28.2 4.4 0.026 15.2 0.1 4.8 3 0 0 3 3 3 1 SlyX Med9 PF07544.13 GAM19525.1 - 0.00042 20.3 11.1 0.13 12.3 0.1 4.0 3 0 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 CENP-F_leu_zip PF10473.9 GAM19525.1 - 0.0014 18.7 14.0 0.018 15.1 0.2 3.6 3 0 0 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 GAM19525.1 - 0.0041 17.5 11.1 0.21 12.0 0.7 4.4 3 1 0 3 3 3 1 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 GAM19525.1 - 0.0076 16.3 7.6 3.4 7.7 4.6 3.7 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 GAM19525.1 - 0.014 15.6 15.9 0.057 13.7 2.8 3.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RNase_PH PF01138.21 GAM19525.1 - 0.05 14.1 0.1 0.14 12.7 0.1 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 bZIP_1 PF00170.21 GAM19525.1 - 0.23 11.6 9.1 9.3 6.4 0.3 4.1 3 0 0 3 3 3 0 bZIP transcription factor ADIP PF11559.8 GAM19525.1 - 0.29 11.2 18.2 0.09 12.9 6.3 3.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Leu_zip PF15294.6 GAM19525.1 - 0.34 10.4 9.1 0.035 13.6 2.5 2.5 2 0 0 2 2 2 0 Leucine zipper AAA_13 PF13166.6 GAM19525.1 - 0.4 9.3 7.1 1.5 7.4 1.1 2.4 2 0 0 2 2 2 0 AAA domain PriC PF07445.12 GAM19525.1 - 0.4 10.6 8.7 0.23 11.4 2.1 2.6 2 0 0 2 2 2 0 Primosomal replication protein priC V_ATPase_I PF01496.19 GAM19525.1 - 0.46 8.4 6.7 0.35 8.7 1.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family YscO PF07321.12 GAM19525.1 - 0.46 10.4 12.3 5.4 6.9 2.1 3.6 3 0 0 3 3 3 0 Type III secretion protein YscO RasGAP_C PF03836.15 GAM19525.1 - 0.6 10.2 6.8 11 6.2 2.2 3.3 3 0 0 3 3 3 0 RasGAP C-terminus HMMR_N PF15905.5 GAM19525.1 - 0.61 9.5 12.9 0.12 11.9 3.6 3.0 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 GAM19525.1 - 0.7 10.1 14.2 2.5 8.3 4.4 3.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF812 PF05667.11 GAM19525.1 - 0.73 8.7 10.7 0.14 11.0 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Exonuc_VII_L PF02601.15 GAM19525.1 - 0.82 9.2 9.5 2.9 7.4 0.6 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit TBK1_CCD1 PF18394.1 GAM19525.1 - 0.85 9.1 6.2 1.8 8.1 2.7 2.4 2 0 0 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 HMMR_C PF15908.5 GAM19525.1 - 0.97 9.7 6.3 8.2 6.7 0.0 3.3 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor C-terminal Ax_dynein_light PF10211.9 GAM19525.1 - 0.98 9.3 11.1 18 5.2 2.2 3.4 3 0 0 3 3 3 0 Axonemal dynein light chain I_LWEQ PF01608.17 GAM19525.1 - 1.5 9.0 8.0 1 9.6 0.1 3.0 2 0 0 2 2 2 0 I/LWEQ domain YabA PF06156.13 GAM19525.1 - 1.7 9.4 11.6 0.61 10.7 1.0 4.4 4 1 0 4 4 4 0 Initiation control protein YabA ParB PF08775.10 GAM19525.1 - 2 8.9 7.4 9.6 6.7 0.4 3.0 2 0 0 2 2 2 0 ParB family KASH_CCD PF14662.6 GAM19525.1 - 2.2 8.1 17.3 1.4 8.7 0.1 4.1 3 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH ABC_tran_CTD PF16326.5 GAM19525.1 - 2.8 8.3 12.3 0.59 10.4 4.2 3.6 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF4686 PF15742.5 GAM19525.1 - 2.8 7.0 18.3 0.59 9.2 3.6 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4686) CEP63 PF17045.5 GAM19525.1 - 2.8 7.8 16.0 0.15 12.0 4.2 3.5 3 1 0 3 3 3 0 Centrosomal protein of 63 kDa HALZ PF02183.18 GAM19525.1 - 3.2 8.1 13.3 0.061 13.6 0.6 4.1 4 0 0 4 4 3 0 Homeobox associated leucine zipper SKA1 PF07160.12 GAM19525.1 - 3.7 7.3 13.0 10 5.9 5.6 2.8 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Vps51 PF08700.11 GAM19525.1 - 4.7 7.4 7.3 4.1 7.6 1.6 3.4 3 0 0 3 3 2 0 Vps51/Vps67 BRE1 PF08647.11 GAM19525.1 - 4.8 7.3 20.5 0.2 11.8 5.0 4.4 4 0 0 4 4 3 0 BRE1 E3 ubiquitin ligase Laminin_II PF06009.12 GAM19525.1 - 5.1 7.1 17.2 2.1 8.4 0.4 3.7 3 0 0 3 3 3 0 Laminin Domain II Fez1 PF06818.15 GAM19525.1 - 5.1 7.5 12.9 0.77 10.2 1.7 3.1 3 0 0 3 3 3 0 Fez1 XhlA PF10779.9 GAM19525.1 - 6.3 7.1 6.7 2.3 8.5 0.7 3.3 3 0 0 3 3 2 0 Haemolysin XhlA GAS PF13851.6 GAM19525.1 - 7.8 5.8 17.4 1.9 7.8 3.8 4.0 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding DUF1043 PF06295.12 GAM19525.1 - 7.9 6.5 9.4 2 8.5 2.2 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF1043) DUF4795 PF16043.5 GAM19525.1 - 8 6.0 10.7 8.4 5.9 3.4 3.4 3 1 0 3 3 2 0 Domain of unknown function (DUF4795) ZapB PF06005.12 GAM19525.1 - 8.6 6.9 22.3 6.2 7.3 5.0 5.0 4 1 1 5 5 5 0 Cell division protein ZapB HATPase_c PF02518.26 GAM19526.1 - 2.6e-48 163.2 0.0 1.4e-22 80.3 0.0 2.8 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM19526.1 - 2.2e-45 153.4 1.7 3.8e-25 88.2 0.0 3.2 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 GAM19526.1 - 1.3e-30 105.2 7.3 5.6e-16 58.3 0.1 3.5 4 0 0 4 4 4 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 GAM19526.1 - 1.3e-06 28.6 0.0 7.1e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 GAM19526.1 - 7.8e-06 26.1 0.0 3.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 PAS domain HATPase_c_5 PF14501.6 GAM19526.1 - 0.01 15.7 0.6 0.83 9.6 0.1 3.6 3 1 0 3 3 3 0 GHKL domain NOD PF06816.13 GAM19526.1 - 0.014 15.0 0.5 1.3 8.7 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein HPTransfase PF10090.9 GAM19526.1 - 0.043 13.6 0.0 0.75 9.6 0.0 2.6 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain DUF5082 PF16888.5 GAM19526.1 - 0.36 11.1 4.9 0.72 10.1 0.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF724 PF05266.14 GAM19526.1 - 0.44 10.4 6.2 1.7 8.4 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Spore_III_AB PF09548.10 GAM19526.1 - 0.53 10.4 3.8 0.73 9.9 0.3 2.8 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) PWI PF01480.17 GAM19527.1 - 1.8e-23 82.6 0.1 2.6e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 PWI domain Uricase PF01014.18 GAM19528.1 - 4.9e-60 201.5 5.4 2e-35 121.9 2.4 2.1 2 0 0 2 2 2 2 Uricase DNA_pol_B_2 PF03175.13 GAM19529.1 - 0.0017 17.3 0.9 0.0036 16.2 0.2 1.7 1 1 1 2 2 2 1 DNA polymerase type B, organellar and viral FNIP PF05725.12 GAM19530.1 - 2.1e-25 88.6 0.6 6.1e-11 42.3 0.1 3.9 4 0 0 4 4 4 3 FNIP Repeat PLN_propep PF16485.5 GAM19530.1 - 0.015 15.0 0.3 0.038 13.7 0.3 1.6 1 0 0 1 1 1 0 Protealysin propeptide F-box-like PF12937.7 GAM19530.1 - 0.16 11.9 1.8 0.17 11.8 0.5 1.7 2 0 0 2 2 2 0 F-box-like DNase_II PF03265.15 GAM19531.1 - 3.2e-10 39.8 0.2 4.9e-10 39.2 0.2 1.3 1 0 0 1 1 1 1 Deoxyribonuclease II LRR_4 PF12799.7 GAM19532.1 - 6.4e-15 55.0 24.3 0.016 15.7 0.0 11.8 5 3 5 13 13 12 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAM19532.1 - 1.9e-13 49.3 31.0 1.4 9.2 0.1 15.0 15 0 0 15 15 15 4 Leucine Rich repeat IstB_IS21 PF01695.17 GAM19532.1 - 0.0018 18.0 0.0 0.0052 16.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 GAM19532.1 - 0.0038 17.2 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM19532.1 - 0.01 16.2 4.4 0.016 15.6 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 GAM19532.1 - 0.017 15.0 1.3 0.059 13.3 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 GAM19532.1 - 0.031 13.6 0.0 0.031 13.6 0.0 3.0 3 0 0 3 3 2 0 Septin ABC_tran PF00005.27 GAM19532.1 - 0.049 14.1 0.0 0.049 14.1 0.0 4.1 4 0 0 4 4 4 0 ABC transporter LRR_1 PF00560.33 GAM19532.1 - 0.084 13.5 21.9 31 5.7 0.2 11.7 12 1 0 12 12 12 0 Leucine Rich Repeat AAA_24 PF13479.6 GAM19532.1 - 0.13 12.0 0.1 0.58 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAM19532.1 - 0.23 11.8 0.0 0.23 11.8 0.0 4.2 4 0 0 4 4 3 0 AAA domain AAA_28 PF13521.6 GAM19532.1 - 0.38 11.0 2.3 10 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAM19532.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain Pkinase PF00069.25 GAM19534.1 - 1.5e-38 132.7 1.3 2.5e-38 132.0 1.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19534.1 - 9.9e-20 70.9 0.5 1.6e-19 70.3 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM19534.1 - 0.6 8.8 4.0 0.86 8.3 0.0 2.5 3 0 0 3 3 3 0 Fungal protein kinase Macoilin PF09726.9 GAM19534.1 - 8 4.9 14.7 0.29 9.6 6.4 2.0 2 0 0 2 2 2 0 Macoilin family Ribosomal_L32e PF01655.18 GAM19535.1 - 8.8e-46 154.8 0.1 1e-45 154.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CybS PF05328.12 GAM19536.1 - 2.4e-10 40.2 0.4 3.3e-10 39.7 0.4 1.3 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit PseudoU_synth_2 PF00849.22 GAM19537.1 - 1.3e-29 103.3 10.1 1.1e-15 58.0 0.0 3.5 3 1 0 3 3 3 2 RNA pseudouridylate synthase AAA_19 PF13245.6 GAM19537.1 - 1.3 9.3 4.9 0.45 10.9 0.2 2.4 2 2 0 2 2 2 0 AAA domain NCA2 PF08637.10 GAM19538.1 - 7.1e-59 199.3 4.3 7.1e-59 199.3 4.3 2.1 2 1 0 2 2 2 1 ATP synthase regulation protein NCA2 RhoGAP PF00620.27 GAM19539.1 - 7.6e-31 107.0 1.2 1.2e-30 106.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain zf-MYND PF01753.18 GAM19539.1 - 1.1e-10 41.4 10.6 2e-10 40.6 10.6 1.4 1 0 0 1 1 1 1 MYND finger ADH_zinc_N PF00107.26 GAM19540.1 - 2.6e-29 101.8 0.3 4.3e-29 101.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM19540.1 - 2.4e-17 64.2 0.0 6.2e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM19540.1 - 2e-08 34.1 0.0 4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 GAM19540.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase GMC_oxred_N PF00732.19 GAM19541.1 - 5e-46 157.4 0.0 9.1e-46 156.6 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM19541.1 - 1.6e-28 100.0 0.1 2.7e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 GAM19541.1 - 0.0012 19.0 1.1 0.0029 17.8 1.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM19541.1 - 0.02 14.0 2.8 0.021 13.9 1.5 1.6 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 GAM19541.1 - 0.026 14.1 1.2 0.029 13.9 0.2 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM19541.1 - 0.027 13.2 0.1 0.048 12.3 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 GAM19541.1 - 0.081 12.6 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 GAM19541.1 - 0.13 11.5 0.5 0.81 8.9 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAM19541.1 - 0.17 10.9 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein JAB PF01398.21 GAM19542.1 - 6.4e-13 48.7 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Phage_CRI PF05144.14 GAM19542.1 - 0.058 12.7 0.3 0.09 12.1 0.3 1.2 1 0 0 1 1 1 0 Phage replication protein CRI DUF2012 PF09430.10 GAM19543.1 - 6.7e-18 65.0 0.9 2.5e-17 63.2 0.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) Y_Y_Y PF07495.13 GAM19543.1 - 0.025 14.5 0.1 0.07 13.1 0.0 1.7 2 0 0 2 2 2 0 Y_Y_Y domain CarboxypepD_reg PF13620.6 GAM19543.1 - 0.034 14.4 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Peptidase_M66 PF10462.9 GAM19544.1 - 1.2e-34 119.7 0.0 1.4e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 GAM19544.1 - 0.0038 17.7 0.2 0.0066 17.0 0.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAM19544.1 - 0.049 13.3 0.2 0.073 12.7 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAM19544.1 - 0.1 12.5 0.5 0.15 11.9 0.5 1.4 1 1 0 1 1 1 0 Matrixin Metallopep PF12044.8 GAM19544.1 - 0.14 10.7 0.3 0.23 10.0 0.3 1.2 1 0 0 1 1 1 0 Putative peptidase family TALPID3 PF15324.6 GAM19545.1 - 0.88 7.2 10.2 0.72 7.5 10.2 1.2 1 0 0 1 1 1 0 Hedgehog signalling target SdrD_B PF17210.3 GAM19546.1 - 1.5e-06 28.4 0.1 1.5e-06 28.4 0.1 5.0 5 1 0 6 6 6 1 SdrD B-like domain DUF2012 PF09430.10 GAM19546.1 - 0.11 12.7 0.0 9.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) P2X_receptor PF00864.19 GAM19547.1 - 3.6e-21 75.7 6.0 2e-10 40.3 1.3 2.9 2 1 1 3 3 3 3 ATP P2X receptor VPS13_C PF16909.5 GAM19548.1 - 2.2e-12 47.1 1.2 3.1e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 GAM19548.1 - 2.3e-07 31.1 0.0 4.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 GAM19549.1 - 1.1e-59 202.1 4.9 1.1e-59 202.1 4.9 7.2 8 0 0 8 8 8 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 GAM19549.1 - 7.8e-58 195.7 23.3 3.7e-51 173.8 0.3 6.6 6 0 0 6 6 6 4 Repeating coiled region of VPS13 SHR-BD PF06650.12 GAM19549.1 - 1.4e-40 139.4 0.4 1.4e-40 139.4 0.4 4.3 5 1 0 5 5 5 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 GAM19549.1 - 2.7e-34 117.8 9.1 4.2e-34 117.2 1.0 4.3 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 GAM19549.1 - 4.4e-14 52.6 2.6 1.6e-13 50.8 0.9 3.0 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Pkinase PF00069.25 GAM19550.1 - 6.7e-67 225.6 0.0 8.5e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19550.1 - 2.3e-48 164.7 0.0 3.5e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1241 PF06840.11 GAM19550.1 - 1.8e-06 27.6 0.1 5.1e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Pkinase_fungal PF17667.1 GAM19550.1 - 0.00016 20.6 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAM19550.1 - 0.00029 20.3 0.1 0.0054 16.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAM19550.1 - 0.013 14.4 0.2 0.19 10.6 0.2 2.1 1 1 0 1 1 1 0 Haspin like kinase domain MCU PF04678.13 GAM19551.1 - 2e-44 151.8 0.0 2.7e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter COR PF16095.5 GAM19551.1 - 1.4e-06 28.3 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Peptidase_M14 PF00246.24 GAM19552.1 - 2.4e-69 234.4 0.4 3.2e-69 233.9 0.4 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 GAM19552.1 - 2.3e-06 27.8 0.0 4.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 GAM19552.1 - 0.00011 22.1 0.3 0.00025 21.0 0.3 1.7 1 0 0 1 1 1 1 CarboxypepD_reg-like domain AstE_AspA PF04952.14 GAM19552.1 - 0.0012 18.0 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family PEGA PF08308.11 GAM19552.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 PEGA domain DUF2817 PF10994.8 GAM19552.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) PI31_Prot_N PF11566.8 GAM19552.1 - 0.14 11.9 0.2 8 6.2 0.0 2.7 3 0 0 3 3 3 0 PI31 proteasome regulator N-terminal EF-hand_7 PF13499.6 GAM19553.1 - 1.4e-20 73.5 8.5 1e-07 32.3 1.3 5.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 GAM19553.1 - 5.5e-20 69.4 16.6 7.6e-05 22.0 0.5 5.7 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.6 GAM19553.1 - 6e-17 60.1 15.3 0.001 18.8 0.1 6.4 5 1 1 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 GAM19553.1 - 7.8e-14 50.4 14.9 0.0006 19.2 0.6 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAM19553.1 - 1.9e-12 46.8 9.5 0.00072 19.4 0.1 4.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 GAM19553.1 - 4.1e-06 26.7 3.6 0.45 10.5 0.1 3.6 2 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand VCBS PF13517.6 GAM19553.1 - 0.00057 20.4 0.2 1.5 9.5 0.0 3.9 4 0 0 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SPARC_Ca_bdg PF10591.9 GAM19553.1 - 0.0011 19.3 0.1 0.031 14.6 0.0 3.0 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Toprim PF01751.22 GAM19553.1 - 0.0068 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF5305 PF17231.2 GAM19553.1 - 0.028 13.8 1.0 0.081 12.3 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Dockerin_1 PF00404.18 GAM19553.1 - 0.047 13.9 2.9 4.5 7.5 0.1 3.1 3 1 1 4 4 4 0 Dockerin type I domain Pkinase PF00069.25 GAM19554.1 - 7.1e-33 114.1 0.1 1e-32 113.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19554.1 - 1.9e-21 76.5 0.0 2.5e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM19554.1 - 2.5e-05 23.3 0.0 2.5e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAM19554.1 - 0.002 18.1 0.0 0.067 13.1 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Menin PF05053.13 GAM19554.1 - 6.8 4.9 7.0 9 4.5 7.0 1.1 1 0 0 1 1 1 0 Menin Prefoldin_2 PF01920.20 GAM19555.1 - 2.8e-14 53.0 7.9 3.5e-14 52.6 7.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4618 PF15397.6 GAM19555.1 - 0.00033 20.2 6.7 0.00053 19.5 6.7 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) DUF2408 PF10303.9 GAM19555.1 - 0.014 15.9 1.5 0.021 15.4 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) E2F_CC-MB PF16421.5 GAM19555.1 - 0.017 15.4 3.6 0.9 9.9 0.7 2.3 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain DUF4132 PF13569.6 GAM19555.1 - 0.033 14.0 0.3 0.1 12.4 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4132) Lectin_N PF03954.14 GAM19555.1 - 0.078 12.7 1.8 0.48 10.2 0.2 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Seryl_tRNA_N PF02403.22 GAM19555.1 - 0.16 12.2 7.4 1 9.6 1.8 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 GAM19555.1 - 0.32 9.9 8.4 1.5 7.7 0.8 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 GAM19555.1 - 0.34 10.9 9.5 0.19 11.7 1.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 GAM19555.1 - 0.42 10.9 6.8 5.7 7.2 1.9 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1640 PF07798.11 GAM19555.1 - 1.1 9.3 8.3 0.94 9.5 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) BST2 PF16716.5 GAM19555.1 - 2.5 8.7 8.7 23 5.7 2.6 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 XhlA PF10779.9 GAM19555.1 - 3.2 8.0 8.1 15 5.9 1.5 2.5 2 1 0 2 2 2 0 Haemolysin XhlA IBR PF01485.21 GAM19556.1 - 6.7e-19 67.9 39.9 7.3e-13 48.5 6.6 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain CUE PF02845.16 GAM19556.1 - 1.1e-07 31.4 0.2 2.4e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 CUE domain zf-C3HC4 PF00097.25 GAM19556.1 - 5.6e-05 22.9 8.2 5.6e-05 22.9 8.2 4.5 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM19556.1 - 5.8e-05 23.3 7.8 5.8e-05 23.3 7.8 4.3 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 GAM19556.1 - 0.005 16.6 5.2 0.005 16.6 5.2 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM19556.1 - 0.054 13.5 31.4 0.037 14.1 6.3 3.9 3 0 0 3 3 3 0 RING-type zinc-finger Lipase_GDSL_3 PF14606.6 GAM19556.1 - 0.1 12.7 0.4 0.17 12.0 0.4 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Cwf_Cwc_15 PF04889.12 GAM19556.1 - 0.27 10.9 5.9 0.41 10.4 5.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mob_synth_C PF06463.13 GAM19556.1 - 1.2 9.1 8.0 0.17 11.8 1.3 2.7 3 0 0 3 3 3 0 Molybdenum Cofactor Synthesis C Pectate_lyase_3 PF12708.7 GAM19557.1 - 0.00091 19.1 2.4 0.0011 18.9 0.3 2.1 1 1 0 2 2 2 1 Pectate lyase superfamily protein Aldedh PF00171.22 GAM19558.1 - 1.4e-101 340.3 0.0 1.7e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_1 PF00175.21 GAM19559.1 - 4.2e-19 69.2 0.2 1.9e-18 67.1 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 GAM19559.1 - 1.2e-18 67.0 0.0 2.9e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 GAM19559.1 - 2.3e-08 34.3 0.0 5.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAM19559.1 - 0.00068 19.8 6.4 0.00092 19.4 0.1 3.2 3 1 1 4 4 4 1 Ferric reductase NAD binding domain PEX11 PF05648.14 GAM19560.1 - 2e-48 164.8 9.6 1.1e-47 162.4 9.6 1.8 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF1324 PF07038.11 GAM19561.1 - 0.056 13.7 0.0 0.78 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) Beta-lactamase2 PF13354.6 GAM19562.1 - 2.9e-05 23.8 0.0 0.00024 20.8 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase enzyme family DUF1459 PF07312.11 GAM19562.1 - 0.0015 18.7 2.2 0.32 11.3 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1459) MFS_1 PF07690.16 GAM19563.1 - 2.1e-56 191.4 54.2 1.1e-55 189.0 54.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAM19563.1 - 8.5e-22 77.3 29.1 1.3e-21 76.7 29.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAM19563.1 - 4.2e-13 49.0 45.5 8.9e-13 47.9 17.0 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 GAM19563.1 - 0.0034 15.8 16.2 0.034 12.5 3.7 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Enolase_C PF00113.22 GAM19564.1 - 4.8e-145 482.3 0.0 8.2e-145 481.6 0.0 1.4 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GAM19564.1 - 8.3e-61 203.9 0.4 1.3e-60 203.3 0.4 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GAM19564.1 - 3.7e-08 33.2 0.0 5.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GAM19564.1 - 0.00017 20.8 0.4 0.00037 19.7 0.0 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus FlaA PF04620.12 GAM19564.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Flagellar filament outer layer protein Flaa zf-C3HC4_2 PF13923.6 GAM19565.1 - 3.5e-09 36.4 11.8 3.5e-09 36.4 11.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM19565.1 - 2.4e-08 33.7 13.0 2.4e-08 33.7 13.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GAM19565.1 - 8e-08 32.1 4.0 1.9e-07 30.8 4.0 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein SAP PF02037.27 GAM19565.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-C3HC4_3 PF13920.6 GAM19565.1 - 2.3e-06 27.3 8.2 2.3e-06 27.3 8.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM19565.1 - 9.2e-06 25.5 10.7 9.2e-06 25.5 10.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAM19565.1 - 1.8e-05 25.0 11.4 1.8e-05 25.0 11.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 GAM19565.1 - 9.1e-05 22.4 9.4 9.1e-05 22.4 9.4 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAM19565.1 - 0.0005 20.2 12.6 0.0005 20.2 12.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 GAM19565.1 - 0.006 16.6 4.1 0.013 15.5 4.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 GAM19565.1 - 0.062 13.5 0.6 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 U-box domain zf-RING_10 PF16685.5 GAM19565.1 - 0.065 13.4 6.5 0.17 12.0 6.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 YacG PF03884.14 GAM19565.1 - 0.067 12.9 2.7 3.1 7.6 0.1 3.3 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Hid1 PF12722.7 GAM19565.1 - 0.39 8.8 18.2 0.12 10.4 2.0 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein zf-RING_4 PF14570.6 GAM19565.1 - 0.65 9.8 13.9 0.12 12.2 8.5 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 GAM19565.1 - 1 9.3 18.5 2.7 7.9 14.8 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Rubredoxin PF00301.20 GAM19565.1 - 2.8 8.0 5.8 2.6 8.2 0.1 3.3 4 0 0 4 4 4 0 Rubredoxin zf-H2C2_2 PF13465.6 GAM19565.1 - 9.7 6.8 14.4 1.1 9.9 4.7 3.4 3 1 0 3 3 3 0 Zinc-finger double domain AAA PF00004.29 GAM19566.1 - 7.3e-58 194.7 0.0 1.2e-42 145.5 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 GAM19566.1 - 1.2e-26 92.9 3.3 3.9e-26 91.3 3.3 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 GAM19566.1 - 8.1e-14 52.4 0.4 1.3e-06 29.0 0.0 3.9 3 1 1 4 4 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 GAM19566.1 - 2.6e-12 46.3 0.0 2.6e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 GAM19566.1 - 4e-08 33.3 0.1 0.0077 16.2 0.0 4.1 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 GAM19566.1 - 1.2e-07 31.5 0.5 0.013 15.1 0.1 3.3 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 GAM19566.1 - 2.5e-07 31.1 0.2 0.16 12.3 0.0 4.3 2 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 GAM19566.1 - 7.8e-07 29.5 0.0 0.043 14.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 GAM19566.1 - 1.7e-06 27.9 0.0 0.043 13.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAM19566.1 - 2.6e-06 27.0 0.2 0.011 15.1 0.1 2.9 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 GAM19566.1 - 1.6e-05 24.9 0.1 0.14 12.1 0.1 3.3 3 0 0 3 3 3 2 NACHT domain RuvB_N PF05496.12 GAM19566.1 - 2.1e-05 24.3 0.0 0.00047 19.9 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAM19566.1 - 2.7e-05 24.7 0.4 0.17 12.5 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.6 GAM19566.1 - 5.5e-05 23.4 0.0 0.19 11.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 GAM19566.1 - 0.00021 21.8 0.7 1.5 9.3 0.0 3.3 3 0 0 3 3 2 2 ABC transporter TIP49 PF06068.13 GAM19566.1 - 0.00034 19.9 0.1 0.09 12.0 0.0 2.6 2 0 0 2 2 2 1 TIP49 P-loop domain Sigma54_activat PF00158.26 GAM19566.1 - 0.00038 20.2 0.0 0.1 12.3 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 GAM19566.1 - 0.00041 20.4 0.0 0.42 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAM19566.1 - 0.00043 20.5 0.0 0.033 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NB-ARC PF00931.22 GAM19566.1 - 0.0011 18.2 0.0 1.5 7.9 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain Rad17 PF03215.15 GAM19566.1 - 0.0011 18.9 0.3 0.0093 15.9 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_28 PF13521.6 GAM19566.1 - 0.0021 18.3 0.1 3.2 8.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAM19566.1 - 0.0038 16.8 0.0 3 7.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 GAM19566.1 - 0.0049 16.6 0.1 0.48 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GAM19566.1 - 0.0058 17.1 0.4 0.14 12.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain CDC48_N PF02359.18 GAM19566.1 - 0.006 16.7 0.0 0.55 10.5 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 GAM19566.1 - 0.0066 16.2 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TsaE PF02367.17 GAM19566.1 - 0.0076 16.2 0.1 0.28 11.2 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 GAM19566.1 - 0.0077 15.9 0.0 0.97 9.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain PhoH PF02562.16 GAM19566.1 - 0.012 15.1 0.6 2.9 7.3 0.3 2.5 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 GAM19566.1 - 0.013 14.5 0.1 2.5 7.1 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 GAM19566.1 - 0.028 13.7 0.2 3.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 GAM19566.1 - 0.029 14.3 0.0 1.9 8.3 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 GAM19566.1 - 0.033 14.3 0.1 3.4 7.8 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF5077 PF16871.5 GAM19566.1 - 0.08 12.8 0.0 5.1 7.0 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5077) ATPase PF06745.13 GAM19566.1 - 0.37 10.1 3.6 6.1 6.1 0.0 3.5 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.6 GAM19566.1 - 0.68 10.4 7.3 6.1 7.3 0.2 3.6 3 1 0 3 3 3 0 AAA domain ATP-synt_C PF00137.21 GAM19567.1 - 2.7e-29 101.3 30.1 1.6e-14 54.0 12.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.24 GAM19567.1 - 0.017 14.7 0.1 0.017 14.7 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L SLATT_5 PF18160.1 GAM19567.1 - 0.032 13.6 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 ATP-synt_C PF00137.21 GAM19568.1 - 5e-28 97.2 35.8 1.4e-17 63.8 15.4 2.2 2 0 0 2 2 2 2 ATP synthase subunit C CBS PF00571.28 GAM19569.1 - 1.9e-30 105.1 6.1 2.4e-12 47.1 0.8 4.3 4 0 0 4 4 4 4 CBS domain Pro-kuma_activ PF09286.11 GAM19570.1 - 4.7e-30 104.7 0.1 7.3e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM19570.1 - 1.4e-06 27.8 0.4 3.5e-06 26.5 0.4 1.6 1 1 0 1 1 1 1 Subtilase family Methyltransf_25 PF13649.6 GAM19571.1 - 3.2e-10 40.6 0.2 9.8e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM19571.1 - 9.2e-09 35.3 1.3 1.9e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM19571.1 - 3.2e-08 34.1 0.0 5.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAM19571.1 - 7.1e-07 28.8 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 GAM19571.1 - 2.4e-06 27.5 0.0 2.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAM19571.1 - 4.1e-06 26.9 0.0 6.8e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAM19571.1 - 3.5e-05 23.8 0.1 7.6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAM19571.1 - 7.5e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 GAM19571.1 - 0.00011 21.8 0.3 0.00037 20.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 GAM19571.1 - 0.00011 22.0 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 GAM19571.1 - 0.00017 22.3 0.5 0.0004 21.1 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 GAM19571.1 - 0.00058 19.4 0.0 0.00082 19.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 N6_N4_Mtase PF01555.18 GAM19571.1 - 0.00083 19.1 0.1 0.0017 18.1 0.0 1.5 2 0 0 2 2 2 1 DNA methylase MTS PF05175.14 GAM19571.1 - 0.0011 18.5 0.2 0.0026 17.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.18 GAM19571.1 - 0.002 17.9 0.1 0.14 11.9 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 GAM19571.1 - 0.0033 16.8 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 GAM19571.1 - 0.0057 16.3 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 GAM19571.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 GAM19571.1 - 0.055 13.3 0.7 0.073 12.9 0.1 1.5 2 0 0 2 2 2 0 Hypothetical methyltransferase Met_10 PF02475.16 GAM19571.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein ETC_C1_NDUFA4 PF04800.12 GAM19572.1 - 8.1e-28 96.5 0.5 2e-27 95.3 0.0 1.7 2 0 0 2 2 2 1 ETC complex I subunit conserved region Med3 PF11593.8 GAM19572.1 - 0.031 13.5 4.7 0.035 13.3 4.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4179 PF13786.6 GAM19572.1 - 0.14 12.6 0.2 0.24 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Spt20 PF12090.8 GAM19572.1 - 0.16 11.6 8.5 0.2 11.3 8.5 1.1 1 0 0 1 1 1 0 Spt20 family SRP54 PF00448.22 GAM19573.1 - 7.2e-53 179.1 2.5 7.2e-53 179.1 2.5 2.5 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 GAM19573.1 - 1.7e-50 172.6 18.8 2.3e-50 172.2 18.8 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 GAM19573.1 - 3.2e-11 43.3 0.0 1.5e-10 41.1 0.0 2.3 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 GAM19573.1 - 3e-05 23.1 0.0 6.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 GAM19573.1 - 6.7e-05 22.9 0.2 0.011 15.7 0.2 2.7 1 1 0 1 1 1 1 NTPase AAA_30 PF13604.6 GAM19573.1 - 7.8e-05 22.5 0.3 0.00026 20.8 0.1 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 GAM19573.1 - 9.6e-05 22.4 0.1 0.00074 19.6 0.0 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 GAM19573.1 - 0.00056 20.2 0.1 0.0026 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 GAM19573.1 - 0.00058 19.5 1.5 0.0022 17.6 1.5 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 GAM19573.1 - 0.0012 19.3 0.0 0.012 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Fer4_NifH PF00142.18 GAM19573.1 - 0.031 13.7 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 GAM19573.1 - 0.039 13.2 0.1 0.074 12.3 0.1 1.4 1 0 0 1 1 1 0 VirC1 protein AAA PF00004.29 GAM19573.1 - 0.041 14.3 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 GAM19573.1 - 0.066 13.1 0.0 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 Adenylylsulphate kinase SPOUT_MTase PF02590.17 GAM19573.1 - 0.22 11.5 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase AAA_31 PF13614.6 GAM19573.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.8 3 1 1 4 4 4 0 AAA domain 2OG-FeII_Oxy_3 PF13640.6 GAM19574.1 - 6.4e-20 71.8 0.0 1.2e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 GAM19574.1 - 8.4e-15 55.2 0.0 1.5e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 GAM19574.1 - 0.041 14.3 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase RRM_1 PF00076.22 GAM19575.1 - 1.6e-18 66.2 0.1 3.6e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM19575.1 - 0.00015 21.8 0.0 0.0004 20.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 GAM19575.1 - 0.00066 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMADHC PF10229.9 GAM19576.1 - 9e-25 87.9 0.0 1e-24 87.8 0.0 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein GrpE PF01025.19 GAM19577.1 - 3.9e-48 163.2 4.5 5.1e-48 162.9 4.5 1.2 1 0 0 1 1 1 1 GrpE SPATA1_C PF15743.5 GAM19577.1 - 0.066 13.3 6.7 0.11 12.6 6.7 1.4 1 1 0 1 1 1 0 Spermatogenesis-associated C-terminus Orn_Arg_deC_N PF02784.16 GAM19577.1 - 0.087 12.2 0.9 1.7 7.9 0.4 2.4 1 1 2 3 3 3 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain FlaG PF03646.15 GAM19577.1 - 2 8.6 9.3 1.2 9.4 5.7 2.2 1 1 1 2 2 2 0 FlaG protein Alg6_Alg8 PF03155.15 GAM19578.1 - 4.6e-138 461.2 42.6 5.8e-138 460.9 42.6 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF1129 PF06570.11 GAM19578.1 - 4.2 6.8 7.4 4.6 6.7 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) APC1_C PF18122.1 GAM19579.1 - 4.2e-19 69.1 2.3 4.2e-19 69.1 2.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 GAM19579.1 - 1.4e-06 28.5 11.3 0.14 12.7 0.0 5.7 5 0 0 5 5 5 3 Proteasome/cyclosome repeat ANAPC1 PF12859.7 GAM19579.1 - 5.7e-05 23.7 7.5 0.0028 18.2 7.5 3.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 SR-25 PF10500.9 GAM19579.1 - 0.92 9.1 5.1 1.9 8.1 5.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MAP65_ASE1 PF03999.12 GAM19580.1 - 0.039 12.6 17.5 0.065 11.9 17.5 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SSP160 PF06933.11 GAM19580.1 - 0.066 11.4 9.7 0.1 10.8 9.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MPM1 PF17234.2 GAM19580.1 - 0.24 11.7 11.5 0.56 10.4 11.5 1.7 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Ndc1_Nup PF09531.10 GAM19580.1 - 0.27 9.9 8.2 0.33 9.6 8.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mucin PF01456.17 GAM19580.1 - 0.57 10.2 22.1 0.2 11.6 18.0 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.8 GAM19580.1 - 0.93 9.5 13.7 0.2 11.6 10.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Androgen_recep PF02166.16 GAM19580.1 - 0.99 8.2 20.2 0.87 8.4 0.6 2.3 2 0 0 2 2 2 0 Androgen receptor PEHE PF15275.6 GAM19580.1 - 1.6 9.4 12.3 0.75 10.4 9.1 2.1 2 0 0 2 2 2 0 PEHE domain LMBR1 PF04791.16 GAM19580.1 - 2.4 7.0 4.0 3.6 6.4 4.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Mcm10 PF09332.11 GAM19580.1 - 4.2 6.7 15.7 13 5.1 14.2 2.0 2 0 0 2 2 2 0 Mcm10 replication factor Presenilin PF01080.17 GAM19580.1 - 4.6 5.9 10.3 6.8 5.3 10.3 1.2 1 0 0 1 1 1 0 Presenilin G-alpha PF00503.20 GAM19581.1 - 1.4e-23 83.6 0.0 1.7e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM19581.1 - 0.032 13.7 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF3584 PF12128.8 GAM19581.1 - 0.066 10.7 0.3 0.1 10.1 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PduV-EutP PF10662.9 GAM19581.1 - 0.15 11.8 0.4 1.7 8.4 0.1 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 GAM19581.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PP2C PF00481.21 GAM19582.1 - 1.9e-68 230.9 0.0 1.9e-68 230.9 0.0 2.1 3 0 0 3 3 3 1 Protein phosphatase 2C Hamartin PF04388.12 GAM19582.1 - 0.19 10.3 22.3 0.26 9.9 22.3 1.1 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 GAM19582.1 - 0.47 10.4 17.5 0.68 9.9 17.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ECM1 PF05782.11 GAM19582.1 - 3 6.7 14.4 4.3 6.1 14.4 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Ly49 PF08391.10 GAM19582.1 - 3.1 8.2 12.8 8.9 6.7 12.8 1.8 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Pkinase PF00069.25 GAM19583.1 - 6.6e-67 225.6 0.0 5.7e-44 150.5 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19583.1 - 1.4e-26 93.4 0.0 2.8e-20 72.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase FNIP PF05725.12 GAM19583.1 - 8.6e-11 41.8 1.2 3.5e-06 27.1 0.1 2.7 1 1 1 2 2 2 2 FNIP Repeat Haspin_kinase PF12330.8 GAM19583.1 - 0.00025 20.1 0.1 0.00052 19.1 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM19583.1 - 0.00038 19.8 0.1 0.0038 16.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAM19583.1 - 0.0028 17.6 0.1 0.0064 16.4 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM19583.1 - 0.027 13.8 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FNIP PF05725.12 GAM19584.1 - 2.3e-34 117.3 1.7 1.5e-05 25.1 0.1 10.4 8 2 2 10 10 10 9 FNIP Repeat LCM PF04072.14 GAM19585.1 - 1.2e-14 54.7 0.0 1.2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DNase_II PF03265.15 GAM19586.1 - 4.3e-05 23.0 0.1 4.8e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Deoxyribonuclease II PsbI PF02532.14 GAM19586.1 - 0.12 12.3 2.0 0.19 11.7 2.0 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Band_7 PF01145.25 GAM19587.1 - 9.4e-08 32.3 2.2 9.4e-08 32.3 2.2 2.2 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 GAM19587.1 - 0.0046 16.7 0.5 0.0089 15.8 0.5 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Myosin_head PF00063.21 GAM19588.1 - 5.5e-268 890.7 11.4 6.6e-268 890.5 11.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAM19588.1 - 1e-40 139.4 0.0 4.1e-40 137.5 0.0 2.0 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 GAM19588.1 - 5.3e-08 32.0 10.6 0.00064 19.3 0.7 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 GAM19588.1 - 0.0033 17.7 0.0 0.051 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAM19588.1 - 0.0039 16.5 0.1 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin ALO PF04030.14 GAM19588.1 - 0.0062 16.4 0.4 0.025 14.4 0.4 2.0 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase AAA_16 PF13191.6 GAM19588.1 - 0.0079 16.6 0.0 0.043 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM19588.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 GAM19588.1 - 0.061 13.9 0.1 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 GAM19588.1 - 0.067 12.7 0.3 10 5.6 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.27 GAM19588.1 - 0.13 12.8 0.3 0.46 11.0 0.1 2.1 2 0 0 2 2 2 0 ABC transporter ARD PF03079.14 GAM19589.1 - 3.8e-43 147.4 0.2 4.5e-43 147.1 0.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 GAM19589.1 - 1.2e-09 37.8 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 GAM19589.1 - 0.00022 21.1 0.0 0.00034 20.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 GAM19589.1 - 0.0022 17.6 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Cupin EF-hand_6 PF13405.6 GAM19590.1 - 0.00014 21.5 0.1 0.00058 19.6 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 GAM19590.1 - 0.00024 21.5 0.1 0.00024 21.5 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 GAM19590.1 - 0.00042 19.7 0.1 0.00099 18.5 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 GAM19590.1 - 0.00057 19.2 0.0 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 GAM19590.1 - 0.049 13.5 0.1 1.1 9.2 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain pair EF_assoc_1 PF08355.12 GAM19590.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 EF hand associated kleA_kleC PF17383.2 GAM19590.1 - 0.36 11.2 2.1 0.91 9.9 2.0 1.7 1 1 0 1 1 1 0 Uncharacterized KorC regulated protein A Zip PF02535.22 GAM19590.1 - 1.4 8.0 4.2 1.7 7.8 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_23 PF13476.6 GAM19590.1 - 5.8 7.4 9.9 1.9 8.9 6.7 1.7 1 1 1 2 2 2 0 AAA domain PPP4R2 PF09184.11 GAM19590.1 - 8.4 5.9 11.7 2.2 7.8 8.5 1.7 2 0 0 2 2 2 0 PPP4R2 DEAD PF00270.29 GAM19591.1 - 2.6e-49 167.3 0.1 6.1e-49 166.2 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM19591.1 - 4.3e-22 78.6 0.2 1.5e-20 73.6 0.0 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAM19591.1 - 1.1e-13 51.2 0.1 3e-13 49.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAM19591.1 - 7.2e-07 29.4 0.6 4.3e-06 26.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 GAM19591.1 - 0.013 15.3 0.0 0.052 13.4 0.0 2.0 1 0 0 1 1 1 0 Helicase dsDNA_bind PF01984.20 GAM19591.1 - 0.08 13.2 1.6 0.93 9.8 0.1 2.5 2 0 0 2 2 2 0 Double-stranded DNA-binding domain AAA_22 PF13401.6 GAM19591.1 - 0.12 12.6 4.2 0.27 11.5 1.2 2.9 3 1 0 3 3 3 0 AAA domain CRM1_C PF08767.11 GAM19592.1 - 2.1e-109 365.6 12.1 2.1e-109 365.6 12.1 3.5 3 2 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 GAM19592.1 - 8.3e-34 116.8 6.4 8.3e-34 116.8 6.4 4.0 4 3 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 GAM19592.1 - 3.6e-31 106.6 0.9 1.8e-30 104.4 0.9 2.3 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 GAM19592.1 - 5.7e-26 90.4 1.9 1.3e-25 89.2 0.8 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 GAM19592.1 - 2.8e-16 59.2 1.9 6.2e-16 58.1 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 GAM19592.1 - 1.1e-14 53.6 1.3 1.1e-14 53.6 1.3 2.1 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat UCH PF00443.29 GAM19592.1 - 0.0027 17.3 0.0 0.015 14.8 0.0 2.3 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HEAT PF02985.22 GAM19592.1 - 0.04 14.2 0.0 76 4.0 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Vac14_Fab1_bd PF12755.7 GAM19592.1 - 0.05 14.2 0.9 3.7 8.2 0.0 4.1 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region TFIIS_M PF07500.14 GAM19592.1 - 0.054 14.0 0.2 0.054 14.0 0.2 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain GRIP PF01465.20 GAM19592.1 - 0.11 12.4 0.3 4.8 7.2 0.0 3.3 3 0 0 3 3 3 0 GRIP domain V-ATPase_H_C PF11698.8 GAM19592.1 - 0.17 12.0 6.0 0.24 11.5 0.1 4.1 4 1 0 4 4 4 0 V-ATPase subunit H TIG PF01833.24 GAM19593.1 - 2.2e-55 184.7 114.9 9e-10 38.5 0.5 14.9 15 0 0 15 15 15 11 IPT/TIG domain DNase_II PF03265.15 GAM19593.1 - 2.2e-27 96.2 1.3 3.2e-16 59.5 1.1 2.6 2 0 0 2 2 2 2 Deoxyribonuclease II SdrD_B PF17210.3 GAM19593.1 - 1.9e-05 24.8 1.8 1.9e-05 24.8 1.8 2.7 2 0 0 2 2 2 1 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM19593.1 - 0.00033 20.9 4.4 0.0097 16.2 0.5 4.1 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain LRR_8 PF13855.6 GAM19595.1 - 0.00041 20.1 5.2 0.00086 19.0 0.8 2.9 2 1 1 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 GAM19595.1 - 0.00074 19.4 10.4 0.89 9.8 0.4 5.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 GAM19595.1 - 0.036 14.5 15.5 0.094 13.2 1.0 4.8 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) GATA PF00320.27 GAM19596.1 - 1.2e-10 40.8 4.6 2.5e-10 39.8 4.6 1.6 1 0 0 1 1 1 1 GATA zinc finger Nucleo_P87 PF07267.11 GAM19596.1 - 0.31 9.8 4.6 0.37 9.6 4.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NIF PF03031.18 GAM19597.1 - 1.8e-17 63.6 0.1 3.2e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DDHD PF02862.17 GAM19597.1 - 0.005 17.0 0.8 0.0071 16.5 0.8 1.3 1 0 0 1 1 1 1 DDHD domain Connexin PF00029.19 GAM19597.1 - 0.016 14.9 4.6 0.025 14.3 4.6 1.2 1 0 0 1 1 1 0 Connexin DUF913 PF06025.12 GAM19597.1 - 0.036 13.1 3.2 0.055 12.4 3.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nucleoside_tran PF01733.18 GAM19597.1 - 0.037 13.4 2.4 0.054 12.9 2.4 1.1 1 0 0 1 1 1 0 Nucleoside transporter LRRC37AB_C PF14914.6 GAM19597.1 - 0.039 13.9 3.4 0.065 13.1 3.4 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF5308 PF17233.2 GAM19597.1 - 0.049 13.8 2.5 0.08 13.2 2.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) V_ATPase_I PF01496.19 GAM19597.1 - 0.057 11.3 8.1 0.09 10.7 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CSG2 PF16965.5 GAM19597.1 - 0.059 12.3 1.8 0.09 11.7 1.8 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator CDC45 PF02724.14 GAM19597.1 - 0.071 11.4 5.9 0.12 10.7 5.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Folate_carrier PF01770.18 GAM19597.1 - 0.075 11.8 4.0 0.1 11.3 4.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier AAA_11 PF13086.6 GAM19597.1 - 0.081 12.7 7.7 0.094 12.5 6.6 1.6 2 0 0 2 2 1 0 AAA domain Ureide_permease PF07168.11 GAM19597.1 - 0.09 11.5 3.0 0.17 10.6 3.0 1.4 1 0 0 1 1 1 0 Ureide permease CPSF100_C PF13299.6 GAM19597.1 - 0.1 12.8 5.3 0.18 12.0 5.3 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 GAM19597.1 - 0.11 12.2 4.8 0.2 11.3 4.8 1.4 1 0 0 1 1 1 0 FAM176 family DUF2370 PF10176.9 GAM19597.1 - 0.13 11.9 2.5 0.22 11.1 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4820 PF16091.5 GAM19597.1 - 0.22 10.9 6.4 0.34 10.2 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3464 PF11947.8 GAM19597.1 - 0.32 10.7 6.9 0.6 9.9 6.9 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 GAM19597.1 - 0.33 9.7 8.3 0.47 9.2 8.3 1.2 1 0 0 1 1 1 0 Presenilin OATP PF03137.20 GAM19597.1 - 0.37 9.0 3.8 0.51 8.6 3.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.15 GAM19597.1 - 0.53 9.2 2.9 0.71 8.7 2.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4175 PF13779.6 GAM19597.1 - 0.6 7.9 17.1 0.76 7.6 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EIIBC-GUT_N PF03612.14 GAM19597.1 - 0.63 9.8 9.4 1.1 9.0 9.4 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Band_3_cyto PF07565.13 GAM19597.1 - 0.78 9.5 5.8 1.2 8.9 5.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CLN3 PF02487.17 GAM19597.1 - 0.79 8.7 5.8 1.1 8.2 5.8 1.1 1 0 0 1 1 1 0 CLN3 protein SID-1_RNA_chan PF13965.6 GAM19597.1 - 0.91 7.9 2.7 1.2 7.4 2.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2722 PF10846.8 GAM19597.1 - 1.3 7.8 18.5 2 7.3 18.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ETRAMP PF09716.10 GAM19597.1 - 1.4 9.0 4.6 4 7.6 4.6 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Peptidase_S49_N PF08496.10 GAM19597.1 - 1.6 8.8 13.2 0.95 9.5 10.2 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal EMC3_TMCO1 PF01956.16 GAM19597.1 - 1.8 8.3 5.3 3.1 7.5 5.3 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Neur_chan_memb PF02932.16 GAM19597.1 - 1.8 8.6 3.7 2.7 8.0 3.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PRC2_HTH_1 PF18118.1 GAM19597.1 - 1.9 9.4 14.6 1.3 9.9 11.9 2.1 3 0 0 3 3 1 0 Polycomb repressive complex 2 tri-helical domain DUF4407 PF14362.6 GAM19597.1 - 2.3 7.5 9.3 4 6.7 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 GAM19597.1 - 2.9 6.6 6.7 4.4 6.0 6.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter EOS1 PF12326.8 GAM19597.1 - 5.3 6.9 4.8 9.4 6.1 4.8 1.4 1 0 0 1 1 1 0 N-glycosylation protein PBP_sp32 PF07222.12 GAM19597.1 - 5.4 6.4 14.5 9.1 5.7 14.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Coilin_N PF15862.5 GAM19597.1 - 6.2 6.6 15.5 14 5.5 15.5 1.5 1 0 0 1 1 1 0 Coilin N-terminus RRM PF10378.9 GAM19597.1 - 7.5 6.4 7.0 52 3.7 7.0 2.4 1 1 0 1 1 1 0 Putative RRM domain DUF866 PF05907.13 GAM19598.1 - 2.5e-39 134.7 3.6 2.8e-39 134.5 3.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) ACBP PF00887.19 GAM19599.1 - 3.1e-23 81.8 3.2 3.4e-23 81.6 3.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Mito_carr PF00153.27 GAM19600.1 - 5.5e-61 202.5 5.1 1.1e-19 70.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SPW PF03779.14 GAM19600.1 - 0.017 14.7 0.1 0.07 12.7 0.0 2.0 2 0 0 2 2 2 0 SPW repeat Form-deh_trans PF09163.11 GAM19600.1 - 3.2 7.6 4.4 1.2 9.0 0.3 2.4 3 0 0 3 3 3 0 Formate dehydrogenase N, transmembrane Sec16_C PF12931.7 GAM19601.1 - 1.1e-52 179.6 0.0 5.9e-52 177.2 0.0 2.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 GAM19601.1 - 4.2e-17 62.8 0.0 4.2e-17 62.8 0.0 4.7 4 1 1 5 5 5 1 Vesicle coat trafficking protein Sec16 mid-region Dockerin_1 PF00404.18 GAM19601.1 - 0.87 9.8 3.3 0.78 10.0 0.0 2.3 2 0 0 2 2 2 0 Dockerin type I domain bZIP_1 PF00170.21 GAM19602.1 - 5e-08 32.9 4.8 5e-08 32.9 4.8 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAM19602.1 - 1e-05 25.5 8.8 1e-05 25.5 8.8 3.2 4 0 0 4 4 4 1 Basic region leucine zipper DUF3439 PF11921.8 GAM19602.1 - 0.16 11.9 2.2 0.57 10.1 2.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Macoilin PF09726.9 GAM19602.1 - 0.44 9.1 34.2 0.24 9.9 18.2 2.2 2 0 0 2 2 2 0 Macoilin family FtsH_ext PF06480.15 GAM19602.1 - 2.3 8.6 8.6 1 9.7 1.7 2.7 2 0 0 2 2 2 0 FtsH Extracellular Mucin PF01456.17 GAM19602.1 - 6.7 6.7 11.0 1.2 9.1 6.2 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein PDCD2_C PF04194.13 GAM19603.1 - 6.6e-33 114.2 4.0 6.6e-33 114.2 4.0 3.0 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 GAM19603.1 - 4.9e-05 23.3 14.7 4.9e-05 23.3 14.7 3.1 3 1 0 3 3 3 1 MYND finger Autophagy_act_C PF03987.15 GAM19603.1 - 0.071 13.7 1.0 0.23 12.1 1.0 1.9 1 0 0 1 1 1 0 Autophagocytosis associated protein, active-site domain LRV_FeS PF05484.11 GAM19603.1 - 0.37 10.8 6.4 1.1 9.3 6.4 1.8 1 0 0 1 1 1 0 LRV protein FeS4 cluster NOT2_3_5 PF04153.18 GAM19605.1 - 1.7e-26 92.8 0.5 1.7e-26 92.8 0.5 3.0 3 1 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Adenine_glyco PF03352.13 GAM19606.1 - 6.4e-69 231.3 0.0 8.9e-69 230.8 0.0 1.2 1 0 0 1 1 1 1 Methyladenine glycosylase Haemadin PF09065.10 GAM19606.1 - 2.5 8.0 4.1 1.1 9.1 1.0 1.9 2 0 0 2 2 2 0 Haemadin Tctex-1 PF03645.13 GAM19607.1 - 1.4e-32 112.0 0.8 1.7e-32 111.8 0.8 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF3597 PF12200.8 GAM19607.1 - 0.022 15.3 0.0 0.028 15.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF2368 PF10166.9 GAM19608.1 - 1.7e-23 82.7 0.5 1.7e-23 82.7 0.5 2.2 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2368) MFS_1 PF07690.16 GAM19608.1 - 8.8e-19 67.6 60.2 2.2e-15 56.4 22.7 2.9 2 1 0 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 GAM19608.1 - 0.0034 15.7 0.0 0.0034 15.7 0.0 2.1 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family eIF3g PF12353.8 GAM19609.1 - 0.035 14.5 1.4 0.1 13.0 1.4 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF4750 PF15938.5 GAM19610.1 - 7.5e-12 44.7 0.7 9.2e-12 44.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) GAIN PF16489.5 GAM19611.1 - 0.18 11.2 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain Cation_ATPase_C PF00689.21 GAM19612.1 - 4.3e-36 124.3 10.2 4.3e-36 124.3 10.2 2.9 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAM19612.1 - 6.2e-33 113.8 0.1 6.2e-33 113.8 0.1 3.4 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 GAM19612.1 - 1.1e-16 61.8 0.3 4.2e-16 59.9 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM19612.1 - 6.7e-09 35.3 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM19612.1 - 1.2e-07 31.8 1.8 3.1e-05 23.9 1.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM19612.1 - 3.7e-06 26.9 0.0 7e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 Cation transport ATPase (P-type) TMEM40 PF15817.5 GAM19612.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 40 family Phage_holin_2_3 PF16080.5 GAM19612.1 - 0.13 12.1 1.0 0.39 10.5 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 GpcrRhopsn4 PF10192.9 GAM19613.1 - 2.1e-77 260.0 19.5 3e-77 259.5 19.5 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 GAM19613.1 - 3e-05 23.4 15.7 5.4e-05 22.6 15.7 1.4 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF2569 PF10754.9 GAM19613.1 - 0.006 17.0 0.2 0.006 17.0 0.2 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2569) DUF2427 PF10348.9 GAM19613.1 - 2.9 7.7 12.4 0.2 11.5 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) zf-C2H2 PF00096.26 GAM19615.1 - 3.5e-15 55.5 44.8 6.5e-05 23.2 1.8 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM19615.1 - 1.5e-12 47.3 35.9 8.2e-07 29.2 2.4 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM19615.1 - 1.1e-05 25.8 16.1 0.0035 18.0 0.7 6.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 GAM19615.1 - 2.6e-05 24.4 10.7 0.0015 18.7 5.0 3.0 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-met PF12874.7 GAM19615.1 - 6.6e-05 23.2 9.5 0.78 10.2 1.3 5.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type PAP_central PF04928.17 GAM19615.1 - 0.016 14.2 8.2 0.029 13.4 8.2 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain zf-C2H2_11 PF16622.5 GAM19615.1 - 0.027 14.2 1.7 0.027 14.2 1.7 3.4 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2HE PF16278.5 GAM19615.1 - 0.15 12.5 0.3 0.15 12.5 0.3 5.4 4 2 2 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger MAT1 PF06391.13 GAM19615.1 - 1.7 8.5 25.9 0.64 9.8 19.7 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 zf-C2H2_6 PF13912.6 GAM19615.1 - 1.7 8.7 16.7 4.5 7.4 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger Sod_Fe_C PF02777.18 GAM19616.1 - 1.4e-36 124.7 0.2 6.5e-36 122.6 0.0 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAM19616.1 - 1.8e-29 102.0 1.3 2.1e-29 101.8 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain LIM PF00412.22 GAM19617.1 - 6.3e-11 42.3 9.0 8.9e-11 41.9 9.0 1.2 1 0 0 1 1 1 1 LIM domain Meiotic_rec114 PF03525.14 GAM19617.1 - 7.8e-05 21.8 0.7 0.43 9.5 0.0 3.0 1 1 2 3 3 3 3 Meiotic recombination protein rec114 GFRP PF06399.13 GAM19617.1 - 0.15 11.9 0.5 68 3.4 0.0 3.3 3 0 0 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) zf-C3HC4_2 PF13923.6 GAM19617.1 - 0.52 10.2 6.4 0.84 9.5 5.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PI3_PI4_kinase PF00454.27 GAM19620.1 - 1.6e-21 77.3 1.2 2.5e-21 76.6 1.2 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Thioredoxin_16 PF18569.1 GAM19620.1 - 4.5 7.5 6.8 9 6.5 6.8 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain bZIP_1 PF00170.21 GAM19621.1 - 1.6e-05 24.9 12.0 1.6e-05 24.9 12.0 3.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAM19621.1 - 0.0055 16.8 18.2 0.0055 16.8 18.2 3.5 2 2 0 2 2 2 1 Basic region leucine zipper PulA_N1 PF17999.1 GAM19621.1 - 3.2 8.5 6.3 27 5.6 0.1 2.9 2 0 0 2 2 2 0 Pullulanase N1-terminal domain Erv26 PF04148.13 GAM19622.1 - 4.8e-42 144.1 24.6 2.8e-41 141.6 24.6 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3810 PF12725.7 GAM19622.1 - 0.26 10.6 9.9 1.6 8.0 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Tetraspanin PF00335.20 GAM19622.1 - 7.3 6.2 16.4 0.53 10.0 5.7 2.1 1 1 1 2 2 2 0 Tetraspanin family Cpn60_TCP1 PF00118.24 GAM19623.1 - 4.9e-154 513.6 1.6 5.5e-154 513.4 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NDUF_C2 PF06374.11 GAM19623.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Xan_ur_permease PF00860.20 GAM19624.1 - 4.2e-82 275.9 45.9 5.1e-82 275.6 45.9 1.1 1 0 0 1 1 1 1 Permease family DUF2306 PF10067.9 GAM19624.1 - 9.3 6.5 13.7 0.21 11.8 2.0 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) FMN_red PF03358.15 GAM19625.1 - 1.6e-27 96.2 0.0 2.1e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAM19625.1 - 2.2e-05 24.3 0.0 3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold POPLD PF08170.12 GAM19626.1 - 3.1e-24 85.1 0.6 2.9e-23 82.0 0.3 2.5 2 0 0 2 2 2 1 POPLD (NUC188) domain POP1 PF06978.11 GAM19626.1 - 1.3e-21 77.6 4.7 1.3e-21 77.6 4.7 1.9 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 Ras PF00071.22 GAM19627.1 - 1.5e-57 193.7 0.0 1.8e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM19627.1 - 1.5e-20 73.6 0.0 2.1e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM19627.1 - 5.2e-09 35.8 0.0 5.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM19627.1 - 4.4e-05 23.1 0.2 0.00016 21.3 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM19627.1 - 0.00051 20.0 0.8 0.68 9.8 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM19627.1 - 0.00087 19.3 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAM19627.1 - 0.028 13.6 0.1 1.7 7.7 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Viral_cys_rich PF08008.12 GAM19627.1 - 0.089 12.8 0.1 3.6 7.7 0.0 2.3 1 1 1 2 2 2 0 Viral cysteine rich DAO PF01266.24 GAM19628.1 - 2.5e-41 142.4 0.0 3e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM19628.1 - 1.1e-08 34.7 0.9 0.00048 19.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM19628.1 - 1.1e-08 34.3 0.5 0.00056 18.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 GAM19628.1 - 3.8e-08 32.8 0.4 3.1e-05 23.3 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 GAM19628.1 - 9.7e-08 31.5 0.5 0.00012 21.3 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 GAM19628.1 - 5.5e-06 26.5 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM19628.1 - 7.7e-05 22.0 0.0 0.00019 20.7 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAM19628.1 - 0.0001 21.7 0.5 0.22 10.7 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM19628.1 - 0.00014 21.2 0.1 0.00031 20.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAM19628.1 - 0.00015 21.2 0.1 0.00043 19.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.18 GAM19628.1 - 0.00093 17.8 0.3 0.87 8.0 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor 3HCDH_N PF02737.18 GAM19628.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GAM19628.1 - 0.015 15.9 1.1 0.16 12.6 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM19628.1 - 0.018 15.1 0.4 1.8 8.6 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAM19628.1 - 0.028 13.5 0.2 0.099 11.7 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 GAM19628.1 - 0.051 12.9 0.2 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 GAM19628.1 - 0.11 11.6 1.5 1 8.4 0.1 2.2 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Proteasome PF00227.26 GAM19629.1 - 4.4e-46 156.8 0.4 5.5e-46 156.5 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_S5 PF00333.20 GAM19630.1 - 1.7e-28 98.3 2.4 3.2e-28 97.5 2.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 GAM19630.1 - 8.4e-24 82.8 0.1 1.4e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 GAM19630.1 - 2.3 8.8 20.9 6.4 7.4 20.9 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RNB PF00773.19 GAM19631.1 - 1.2e-99 333.8 0.0 1.9e-99 333.1 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GAM19631.1 - 3.9e-20 71.7 0.0 9.6e-20 70.4 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 GAM19631.1 - 5e-16 58.7 0.0 1.1e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain PIN_4 PF13638.6 GAM19631.1 - 3.6e-13 49.9 4.3 4e-13 49.8 2.4 2.2 2 0 0 2 2 2 1 PIN domain Rrp44_S1 PF17215.3 GAM19631.1 - 1.3e-10 41.0 0.1 3.7e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 GAM19631.1 - 7.4e-10 38.9 0.3 4.6e-06 26.7 0.0 3.0 3 0 0 3 3 3 2 Cold shock domain Dis3l2_C_term PF17877.1 GAM19631.1 - 0.0025 18.1 0.0 0.0074 16.6 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Got1 PF04178.12 GAM19632.1 - 2.2e-31 108.6 20.2 2.9e-31 108.2 20.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family SdpI PF13630.6 GAM19632.1 - 5.3 7.3 13.3 13 6.0 0.3 2.4 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF2070 PF09843.9 GAM19632.1 - 5.5 5.2 12.3 6.8 4.9 12.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Inhibitor_I71 PF12628.7 GAM19633.1 - 0.00024 21.0 2.9 0.00024 21.0 2.9 1.6 2 0 0 2 2 2 1 Falstatin, cysteine peptidase inhibitor TMEM223 PF14640.6 GAM19633.1 - 0.0014 18.9 3.4 0.021 15.0 0.2 3.1 2 1 0 2 2 2 1 Transmembrane protein 223 DUF3381 PF11861.8 GAM19633.1 - 0.0053 16.6 6.3 0.0053 16.6 6.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3381) Coilin_N PF15862.5 GAM19633.1 - 0.45 10.3 14.8 0.88 9.4 8.1 2.2 2 0 0 2 2 2 0 Coilin N-terminus DUF2367 PF10164.9 GAM19633.1 - 0.9 10.1 3.5 7.5 7.1 2.2 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) DivIC PF04977.15 GAM19633.1 - 1.2 9.0 15.1 3.8 7.3 4.4 2.5 2 0 0 2 2 2 0 Septum formation initiator Ax_dynein_light PF10211.9 GAM19633.1 - 2.6 7.9 17.8 7.6 6.4 0.5 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain RNA_pol_Rpb6 PF01192.22 GAM19634.1 - 3e-14 52.6 0.1 4.4e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 YhhN PF07947.14 GAM19635.1 - 1.3e-12 47.7 14.5 1.3e-12 47.7 14.5 2.2 2 0 0 2 2 2 1 YhhN family Cupin_8 PF13621.6 GAM19636.1 - 3.1e-06 27.1 0.6 0.0014 18.4 0.0 3.1 3 0 0 3 3 3 2 Cupin-like domain JmjC PF02373.22 GAM19636.1 - 0.017 15.5 0.0 0.052 14.0 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase ParA PF10609.9 GAM19637.1 - 3.7e-99 331.1 1.5 4.4e-99 330.9 1.5 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAM19637.1 - 6.3e-12 45.7 0.0 1.6e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 GAM19637.1 - 1.5e-08 34.4 0.1 6.8e-08 32.3 0.1 1.9 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 GAM19637.1 - 9.6e-07 28.9 1.3 3.5e-06 27.1 1.3 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 GAM19637.1 - 5.9e-05 22.4 0.7 0.012 14.9 0.2 3.0 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 GAM19637.1 - 6e-05 22.5 0.0 9.7e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 GAM19637.1 - 0.0012 18.5 0.1 0.0022 17.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 GAM19637.1 - 0.013 15.4 0.8 0.046 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 GAM19637.1 - 0.098 12.1 0.1 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Ank_2 PF12796.7 GAM19638.1 - 2.9e-82 271.3 18.7 2.9e-15 56.6 0.1 5.4 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19638.1 - 3.3e-45 151.9 4.1 4.5e-09 36.7 0.1 7.4 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19638.1 - 7.9e-40 130.3 6.0 1.9e-06 27.7 0.1 9.5 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 GAM19638.1 - 1e-39 133.2 19.1 5e-06 26.7 0.4 10.1 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 GAM19638.1 - 4e-35 119.4 7.3 8.6e-09 35.5 0.2 7.8 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Homeodomain PF00046.29 GAM19638.1 - 7.3e-18 64.2 0.9 7.3e-18 64.2 0.9 2.1 2 0 0 2 2 2 1 Homeodomain SR-25 PF10500.9 GAM19638.1 - 0.0077 15.9 8.9 0.0077 15.9 8.9 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein VIR_N PF15912.5 GAM19638.1 - 1 8.9 9.6 2.6 7.6 9.6 1.7 1 0 0 1 1 1 0 Virilizer, N-terminal Gelsolin PF00626.22 GAM19639.1 - 7e-31 106.0 1.4 8.1e-11 41.7 0.0 5.8 5 0 0 5 5 5 5 Gelsolin repeat Complex1_LYR PF05347.15 GAM19640.1 - 0.015 15.3 0.6 0.065 13.3 0.2 2.1 2 0 0 2 2 2 0 Complex 1 protein (LYR family) DUF2573 PF10835.8 GAM19640.1 - 0.074 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) FNIP PF05725.12 GAM19641.1 - 1.3e-15 57.2 11.3 5.7e-05 23.2 0.0 7.3 5 1 4 9 9 9 6 FNIP Repeat AAA_21 PF13304.6 GAM19642.1 - 9.3e-05 22.4 0.7 0.0093 15.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAM19642.1 - 0.0025 18.2 0.0 0.0052 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 GAM19642.1 - 0.011 16.3 9.5 0.46 11.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 GAM19642.1 - 0.024 15.0 0.0 0.082 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain SAM_PNT PF02198.16 GAM19642.1 - 0.046 13.7 0.0 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain AAA PF00004.29 GAM19642.1 - 0.07 13.6 0.0 0.27 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAM19642.1 - 0.12 12.3 0.1 1 9.3 0.1 2.2 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 GAM19642.1 - 0.21 11.8 1.7 0.57 10.4 0.0 2.7 3 1 0 3 3 3 0 AAA domain F-box-like PF12937.7 GAM19645.1 - 0.067 13.1 0.3 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 F-box-like YL1 PF05764.13 GAM19647.1 - 0.011 15.8 7.8 0.011 15.8 7.8 1.7 2 0 0 2 2 2 0 YL1 nuclear protein HC2 PF07382.11 GAM19647.1 - 0.025 14.7 13.4 0.042 13.9 13.4 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 CDC45 PF02724.14 GAM19647.1 - 0.098 10.9 6.3 0.15 10.3 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 GAM19647.1 - 0.29 9.9 3.5 0.49 9.2 3.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop14 PF04147.12 GAM19647.1 - 0.38 8.9 5.9 0.57 8.3 5.9 1.2 1 0 0 1 1 1 0 Nop14-like family Roughex PF06020.11 GAM19647.1 - 0.64 9.1 2.8 0.92 8.5 2.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Hc1 PF07432.13 GAM19647.1 - 2 8.8 13.9 4.3 7.7 13.9 1.5 1 0 0 1 1 1 0 Histone H1-like protein Hc1 Alpha_kinase PF02816.18 GAM19648.1 - 8.5e-24 84.7 0.5 1.1e-23 84.3 0.5 1.2 1 0 0 1 1 1 1 Alpha-kinase family G-patch PF01585.23 GAM19648.1 - 0.23 11.4 1.2 0.44 10.5 1.2 1.5 1 0 0 1 1 1 0 G-patch domain DUF2408 PF10303.9 GAM19649.1 - 0.022 15.3 3.1 0.038 14.6 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) BAR PF03114.18 GAM19650.1 - 4.4e-09 36.3 8.0 2.7e-08 33.8 8.0 1.9 1 1 0 1 1 1 1 BAR domain GBP_C PF02841.14 GAM19650.1 - 0.038 13.4 2.3 0.062 12.7 2.3 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Phage_GP20 PF06810.11 GAM19650.1 - 2.2 8.1 8.3 2.4 8.0 6.2 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 MFAP1 PF06991.11 GAM19651.1 - 5.1e-57 193.2 35.3 5.1e-57 193.2 35.3 3.5 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing 5_nucleotid_C PF02872.18 GAM19652.1 - 0.053 13.7 0.0 0.077 13.2 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain RhoGAP PF00620.27 GAM19653.1 - 5e-33 114.1 0.0 1e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Reg_prop PF07494.11 GAM19653.1 - 0.00021 21.1 1.3 1 9.8 0.0 5.2 5 0 0 5 5 5 1 Two component regulator propeller Cytochrom_D1 PF02239.16 GAM19653.1 - 0.026 13.1 3.9 0.31 9.5 0.5 2.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain G8 PF10162.9 GAM19655.1 - 8.1e-19 67.9 0.0 2.5e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 GAM19655.1 - 6.1 6.7 22.8 0.2 11.5 3.4 4.9 6 2 0 6 6 6 0 Right handed beta helix region adh_short PF00106.25 GAM19660.1 - 5.1e-45 153.3 2.0 6.5e-45 153.0 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM19660.1 - 3e-41 141.5 1.5 3.7e-41 141.2 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM19660.1 - 1.8e-15 57.3 1.2 2.8e-15 56.7 1.2 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 GAM19660.1 - 4.8e-06 25.8 1.2 4.8e-05 22.5 1.2 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM19660.1 - 0.00056 19.5 0.6 0.0012 18.4 0.6 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM19660.1 - 0.00067 18.9 0.6 0.015 14.4 0.6 2.2 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 GAM19660.1 - 0.02 15.2 0.5 0.031 14.5 0.5 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Cofilin_ADF PF00241.20 GAM19662.1 - 8.6e-06 25.6 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Kinesin PF00225.23 GAM19663.1 - 1.9e-107 359.1 0.0 1.9e-107 359.1 0.0 3.0 4 1 0 4 4 4 1 Kinesin motor domain Kinesin_assoc PF16183.5 GAM19663.1 - 3.2e-24 86.0 5.3 6.7e-20 72.0 2.1 5.2 2 2 3 5 5 5 2 Kinesin-associated Microtub_bd PF16796.5 GAM19663.1 - 8.3e-21 74.5 1.5 4.8e-20 72.0 0.0 3.0 3 0 0 3 3 3 1 Microtubule binding PH PF00169.29 GAM19663.1 - 1.6e-11 44.7 4.1 4.7e-11 43.1 1.2 3.1 3 0 0 3 3 3 1 PH domain DUF3694 PF12473.8 GAM19663.1 - 2.2e-06 28.4 2.1 0.0085 16.8 0.0 5.1 3 1 0 3 3 3 1 Kinesin protein FHA PF00498.26 GAM19663.1 - 3.7e-06 27.2 0.2 2.2e-05 24.7 0.1 2.5 2 0 0 2 2 2 1 FHA domain PH_8 PF15409.6 GAM19663.1 - 0.0008 19.6 3.7 0.0013 19.0 0.5 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Yop-YscD_cpl PF16697.5 GAM19663.1 - 0.0012 19.1 0.0 0.0047 17.2 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 GAM19663.1 - 0.018 15.5 5.2 0.12 12.8 0.1 3.7 2 0 0 2 2 2 0 Kinesin protein 1B RhoGAP PF00620.27 GAM19664.1 - 6.1e-30 104.1 0.3 3.3e-29 101.7 0.2 2.1 2 0 0 2 2 2 1 RhoGAP domain RRM_1 PF00076.22 GAM19665.1 - 7.4e-08 32.1 0.2 1.3e-07 31.3 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM19665.1 - 0.03 14.2 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 Occluded RNA-recognition motif SH3_9 PF14604.6 GAM19666.1 - 3.9e-26 90.7 3.1 2.5e-14 52.9 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 GAM19666.1 - 3e-23 81.2 0.5 9.4e-12 44.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAM19666.1 - 8.8e-23 79.7 2.5 1.7e-14 53.1 0.1 2.4 2 0 0 2 2 2 2 SH3 domain HR1 PF02185.16 GAM19666.1 - 0.0018 18.3 26.1 0.036 14.2 4.8 3.7 3 1 1 4 4 4 2 Hr1 repeat hSH3 PF14603.6 GAM19666.1 - 0.0027 18.1 0.0 0.011 16.2 0.0 2.0 1 0 0 1 1 1 1 Helically-extended SH3 domain ABC_tran_CTD PF16326.5 GAM19666.1 - 0.0056 16.9 23.3 0.1 12.8 0.2 4.5 3 1 1 4 4 4 2 ABC transporter C-terminal domain DivIC PF04977.15 GAM19666.1 - 0.0075 16.0 23.0 0.055 13.2 2.2 4.2 4 0 0 4 4 4 3 Septum formation initiator Seryl_tRNA_N PF02403.22 GAM19666.1 - 0.021 15.0 24.6 1.1 9.6 6.8 4.0 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.12 GAM19666.1 - 0.024 15.3 0.4 0.024 15.3 0.4 3.6 3 1 0 3 3 3 0 SlyX DUF5348 PF17295.2 GAM19666.1 - 0.12 12.3 0.1 5.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) EF-G-binding_N PF07299.11 GAM19666.1 - 0.46 11.0 7.8 0.5 10.9 1.5 2.8 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal V_ATPase_I PF01496.19 GAM19666.1 - 1.1 7.1 15.3 0.66 7.8 11.8 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PilJ PF13675.6 GAM19666.1 - 1.5 8.8 3.9 0.87 9.6 0.3 2.3 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sulfotransfer_1 PF00685.27 GAM19667.1 - 1.7e-18 67.1 2.9 2.8e-18 66.4 0.2 2.4 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAM19667.1 - 1.9e-12 48.0 2.6 0.00017 22.1 0.0 3.8 3 1 0 4 4 4 3 Sulfotransferase family Ino80_Iec3 PF14612.6 GAM19667.1 - 0.025 15.2 0.3 0.038 14.7 0.3 1.2 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Sulfotransfer_2 PF03567.14 GAM19667.1 - 0.06 13.2 0.7 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Sulfotransferase family DUF4460 PF14687.6 GAM19667.1 - 0.14 12.2 0.9 5.5 7.1 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) WD40 PF00400.32 GAM19668.1 - 7e-28 96.3 17.0 4.4e-06 27.3 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM19668.1 - 1.7e-18 66.7 6.4 4.4e-08 33.3 1.2 4.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM19668.1 - 9e-08 32.2 6.3 0.067 13.1 0.0 4.3 3 1 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM19668.1 - 0.00011 21.3 0.5 0.69 8.8 0.0 3.5 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.5 GAM19668.1 - 0.00016 20.4 0.8 0.00041 19.1 0.0 1.9 3 0 0 3 3 3 1 beta-propeller of ELYS nucleoporin 7tm_3 PF00003.22 GAM19669.1 - 1.7e-29 103.2 30.2 1.7e-29 103.2 30.2 2.3 2 1 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Serglycin PF04360.12 GAM19670.1 - 0.02 14.8 0.4 0.02 14.8 0.4 1.7 2 0 0 2 2 2 0 Serglycin Pex14_N PF04695.13 GAM19673.1 - 1.5 9.4 9.4 0.6 10.8 5.9 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UQ_con PF00179.26 GAM19674.1 - 4e-28 97.8 0.0 7e-28 97.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 GAM19674.1 - 0.0033 17.1 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 GATA PF00320.27 GAM19675.1 - 2.2e-15 56.0 2.8 4.2e-15 55.1 2.8 1.5 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 GAM19675.1 - 0.05 13.9 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon SAS-6_N PF16531.5 GAM19675.1 - 0.16 12.5 2.9 0.52 10.9 2.9 1.8 1 0 0 1 1 1 0 Centriolar protein SAS N-terminal FNIP PF05725.12 GAM19677.1 - 3.4e-82 270.4 64.2 1.3e-13 50.9 0.9 8.7 3 2 8 11 11 11 11 FNIP Repeat DUF1769 PF08588.10 GAM19677.1 - 0.054 13.7 0.2 3.6 7.9 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1769) FNIP PF05725.12 GAM19678.1 - 1.1e-56 188.7 31.6 1.5e-10 41.1 0.1 9.6 4 4 4 10 10 10 10 FNIP Repeat DUF1769 PF08588.10 GAM19678.1 - 0.075 13.2 0.5 36 4.7 0.1 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1769) PCRF PF03462.18 GAM19679.1 - 3.6e-58 196.6 0.2 3.6e-58 196.6 0.2 1.5 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 GAM19679.1 - 2.2e-38 130.7 3.4 4.5e-38 129.7 3.4 1.5 1 0 0 1 1 1 1 RF-1 domain DUF2834 PF11196.8 GAM19680.1 - 0.13 12.7 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) DUF4538 PF15061.6 GAM19680.1 - 0.54 10.0 3.6 0.97 9.2 3.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4538) RELT PF12606.8 GAM19681.1 - 0.13 11.3 5.7 9.7 5.3 0.2 4.8 5 0 0 5 5 5 0 Tumour necrosis factor receptor superfamily member 19 DUF1929 PF09118.11 GAM19681.1 - 1.6 9.0 12.8 12 6.3 0.1 5.3 1 1 5 6 6 6 0 Domain of unknown function (DUF1929) SNAPc_SNAP43 PF09808.9 GAM19682.1 - 7e-31 107.6 0.1 7e-31 107.6 0.1 1.9 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 PI3K_1B_p101 PF10486.9 GAM19682.1 - 2.3 5.9 7.6 3.1 5.5 7.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2053 PF09767.9 GAM19683.1 - 1.1e-42 145.9 2.1 2e-42 145.1 2.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) PIG-F PF06699.11 GAM19683.1 - 0.25 11.5 4.3 0.22 11.7 1.3 2.0 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F PP_kinase PF02503.17 GAM19684.1 - 2.6e-64 216.5 2.2 5.4e-64 215.5 2.2 1.6 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_C PF13090.6 GAM19684.1 - 6.5e-62 208.0 0.0 6.5e-62 208.0 0.0 1.9 2 0 0 2 2 1 1 Polyphosphate kinase C-terminal domain 2 PP_kinase_C_1 PF17941.1 GAM19684.1 - 5.5e-59 198.4 2.2 5.6e-59 198.4 0.1 2.1 3 0 0 3 3 3 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_N PF13089.6 GAM19684.1 - 4.5e-19 68.7 0.7 4.5e-19 68.7 0.7 3.1 3 0 0 3 3 2 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 GAM19684.1 - 2.1e-08 34.2 3.6 0.00044 20.1 0.0 3.6 4 1 0 4 4 4 2 PLD-like domain TRAP_alpha PF03896.16 GAM19684.1 - 0.006 15.8 5.0 0.006 15.8 5.0 2.4 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit SKG6 PF08693.10 GAM19684.1 - 0.96 8.9 4.6 2 7.9 4.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Macoilin PF09726.9 GAM19684.1 - 3.8 6.0 19.8 7 5.1 19.8 1.3 1 0 0 1 1 1 0 Macoilin family GAGA_bind PF06217.12 GAM19684.1 - 4.4 7.5 16.1 10 6.3 16.1 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family Cellulose_synt PF03552.14 GAM19684.1 - 6.4 5.1 7.5 10 4.5 7.5 1.1 1 0 0 1 1 1 0 Cellulose synthase NARP1 PF12569.8 GAM19684.1 - 8.6 5.1 22.8 15 4.4 22.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ank_2 PF12796.7 GAM19685.1 - 1.2e-58 195.6 44.6 1.1e-08 35.5 1.5 8.7 2 1 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19685.1 - 4.9e-39 132.2 25.4 6.3e-05 23.5 0.0 12.9 6 4 7 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM19685.1 - 1.4e-38 130.5 23.9 4.7e-06 26.8 0.3 15.4 6 3 10 17 17 17 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19685.1 - 3.7e-28 94.5 14.0 0.22 12.2 0.0 17.6 18 2 2 20 20 20 6 Ankyrin repeat Ank PF00023.30 GAM19685.1 - 2.4e-07 30.9 11.6 40 4.9 0.0 11.5 8 3 5 13 13 13 0 Ankyrin repeat DUF5049 PF16468.5 GAM19685.1 - 3e-05 23.8 7.3 4.4 7.3 0.1 8.1 9 2 2 11 11 11 2 Domain of unknown function (DUF5049) ENTH PF01417.20 GAM19685.1 - 0.01 15.9 2.4 83 3.2 0.0 6.1 6 2 1 7 7 7 0 ENTH domain betaPIX_CC PF16523.5 GAM19686.1 - 0.11 12.3 14.0 0.059 13.2 11.9 1.8 1 1 0 1 1 1 0 betaPIX coiled coil DOR PF14839.6 GAM19686.1 - 0.21 11.5 7.0 0.26 11.2 7.0 1.2 1 0 0 1 1 1 0 DOR family CDC45 PF02724.14 GAM19686.1 - 0.49 8.6 21.1 0.5 8.6 21.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAM19686.1 - 0.53 8.3 19.8 0.57 8.2 19.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 GAM19686.1 - 1.4 6.9 12.0 1.6 6.7 12.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PDDEXK_6 PF04720.12 GAM19686.1 - 1.5 8.8 12.2 1.9 8.4 12.2 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function DUF4637 PF15470.6 GAM19686.1 - 1.8 8.2 9.8 2.6 7.8 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PRP1_N PF06424.12 GAM19686.1 - 5.8 7.3 19.1 7.4 7.0 19.1 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal VPS9 PF02204.18 GAM19687.1 - 8.9e-23 80.5 0.2 2.7e-22 79.0 0.2 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Pkinase PF00069.25 GAM19688.1 - 5.9e-50 170.1 0.0 1e-49 169.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19688.1 - 5.1e-35 121.0 0.0 8.4e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAM19688.1 - 4e-16 59.1 0.1 1.2e-15 57.6 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 GAM19688.1 - 1.4e-05 24.0 0.0 2.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAM19688.1 - 0.00032 20.1 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SWI-SNF_Ssr4 PF08549.10 GAM19688.1 - 0.34 9.5 8.7 0.52 8.9 8.7 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) TFIIA PF03153.13 GAM19688.1 - 0.49 10.3 11.6 0.68 9.9 11.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 GAM19689.1 - 4.5e-42 144.4 0.3 4.5e-42 144.4 0.3 2.3 1 1 1 2 2 2 1 ZIP Zinc transporter DUF3464 PF11947.8 GAM19689.1 - 0.0081 15.9 2.4 0.026 14.3 2.4 1.9 1 1 0 1 1 1 1 Photosynthesis affected mutant 68 RNA_pol_Rpc4 PF05132.14 GAM19689.1 - 0.016 15.7 1.6 0.024 15.1 1.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 PBP1_TM PF14812.6 GAM19689.1 - 0.021 15.2 8.7 0.042 14.2 8.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 GAM19689.1 - 0.023 12.9 6.7 0.03 12.5 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF3611 PF12263.8 GAM19689.1 - 0.06 13.2 0.5 0.15 11.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF2207 PF09972.9 GAM19689.1 - 0.072 11.8 0.1 0.072 11.8 0.1 2.0 2 1 0 2 2 1 0 Predicted membrane protein (DUF2207) TFIIF_alpha PF05793.12 GAM19689.1 - 1.1 7.7 22.3 1.5 7.3 22.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRAP_alpha PF03896.16 GAM19689.1 - 1.1 8.4 4.4 1.7 7.8 4.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_S49_N PF08496.10 GAM19689.1 - 1.2 9.2 7.5 2.2 8.3 7.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EIIBC-GUT_N PF03612.14 GAM19689.1 - 2.1 8.1 5.8 3.3 7.4 5.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2076 PF09849.9 GAM19689.1 - 2.5 8.1 9.0 0.063 13.3 2.1 1.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) CDC45 PF02724.14 GAM19689.1 - 9.8 4.3 14.8 13 3.9 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Actin PF00022.19 GAM19690.1 - 2e-87 293.4 0.0 2.8e-86 289.7 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAM19690.1 - 0.04 12.7 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein EIIBC-GUT_N PF03612.14 GAM19690.1 - 0.3 10.8 2.8 0.54 10.0 2.8 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 GAM19690.1 - 0.68 8.6 2.0 0.94 8.2 2.0 1.1 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 GAM19690.1 - 4.3 7.1 6.0 7.4 6.3 6.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TFIIB PF00382.19 GAM19691.1 - 0.0013 18.7 0.2 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Chorion_3 PF05387.11 GAM19691.1 - 0.054 13.1 0.1 0.085 12.5 0.1 1.3 1 0 0 1 1 1 0 Chorion family 3 CDC45 PF02724.14 GAM19691.1 - 0.14 10.4 4.8 0.2 9.9 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GAM19691.1 - 1.1 9.3 9.1 2.4 8.2 9.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Pkinase PF00069.25 GAM19693.1 - 4.4e-82 275.4 0.0 5.4e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19693.1 - 2e-40 138.7 0.0 2.8e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM19693.1 - 7.2e-06 25.5 0.2 1.9e-05 24.1 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM19693.1 - 0.012 14.9 0.3 0.28 10.5 0.1 2.6 1 1 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.9 GAM19693.1 - 0.033 13.7 0.1 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.23 GAM19693.1 - 0.037 14.0 0.0 0.077 12.9 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1367 PF07105.11 GAM19693.1 - 0.06 13.0 1.1 0.73 9.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1367) Josephin PF02099.17 GAM19694.1 - 4.8e-48 163.3 0.1 6.5e-48 162.9 0.1 1.2 1 0 0 1 1 1 1 Josephin UIM PF02809.20 GAM19694.1 - 0.002 17.9 1.9 0.002 17.9 1.9 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif Ras PF00071.22 GAM19695.1 - 6.3e-66 220.9 0.1 7.5e-66 220.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM19695.1 - 2.7e-35 121.2 0.0 4.1e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM19695.1 - 1.6e-15 57.0 0.1 2e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM19695.1 - 6.4e-06 25.8 0.2 2.3e-05 24.0 0.1 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAM19695.1 - 3.7e-05 23.2 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM19695.1 - 9.7e-05 22.4 0.0 0.00026 21.0 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM19695.1 - 0.00048 20.1 0.3 0.21 11.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase DUF3963 PF13124.6 GAM19695.1 - 0.0085 16.1 0.2 0.02 14.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3963) SRPRB PF09439.10 GAM19695.1 - 0.0098 15.3 0.0 0.014 14.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MCM PF00493.23 GAM19695.1 - 0.021 13.9 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 GAM19695.1 - 0.053 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM19695.1 - 0.066 13.6 0.0 0.091 13.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 GAM19695.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 GAM19695.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) YARHG PF13308.6 GAM19696.1 - 0.0019 18.1 0.2 0.0035 17.2 0.2 1.5 1 0 0 1 1 1 1 YARHG domain RTC4 PF14474.6 GAM19696.1 - 0.048 13.8 0.6 0.24 11.6 0.4 2.0 2 0 0 2 2 2 0 RTC4-like domain DREV PF05219.12 GAM19697.1 - 1.5e-52 178.4 0.1 3.3e-44 151.0 0.0 2.2 2 0 0 2 2 2 2 DREV methyltransferase Methyltransf_11 PF08241.12 GAM19697.1 - 1.8e-12 47.7 0.0 4e-11 43.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM19697.1 - 7.1e-10 39.0 0.0 5.7e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM19697.1 - 2.2e-09 37.9 0.0 8.7e-08 32.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM19697.1 - 4e-09 37.1 0.0 1.1e-08 35.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM19697.1 - 0.00059 19.7 0.0 0.016 15.0 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 GAM19697.1 - 0.0039 16.3 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Glyc_hyd_38C_2 PF18230.1 GAM19697.1 - 0.085 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal sub-domain PPR_2 PF13041.6 GAM19698.1 - 9.9e-05 22.5 15.7 0.00039 20.6 1.2 5.5 7 0 0 7 7 7 2 PPR repeat family PPR_3 PF13812.6 GAM19698.1 - 0.00086 19.3 2.7 0.0037 17.3 0.0 3.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.20 GAM19698.1 - 0.044 14.0 4.0 1.3 9.5 0.6 4.2 4 0 0 4 4 4 0 PPR repeat ABC2_membrane PF01061.24 GAM19699.1 - 5.1e-90 300.5 66.7 2.3e-49 167.7 27.4 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 GAM19699.1 - 2.9e-39 134.7 0.0 8.8e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAM19699.1 - 2.8e-27 94.4 3.8 2.9e-24 84.8 0.0 4.1 3 1 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAM19699.1 - 3.4e-10 40.4 0.2 1e-09 38.9 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 GAM19699.1 - 4.4e-08 32.6 59.6 1.5e-07 30.8 22.1 3.0 2 1 1 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAM19699.1 - 2.3e-06 27.6 0.1 0.00068 19.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 GAM19699.1 - 6.9e-06 25.7 0.2 0.0043 16.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GAM19699.1 - 2.3e-05 24.4 0.2 0.079 12.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAM19699.1 - 3.1e-05 24.4 0.0 0.013 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 GAM19699.1 - 9.9e-05 22.0 0.0 0.00048 19.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM19699.1 - 0.00031 21.0 0.0 0.29 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAM19699.1 - 0.0026 17.8 0.2 2.1 8.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 GAM19699.1 - 0.0037 17.8 0.5 0.17 12.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 GAM19699.1 - 0.019 14.7 0.2 1.7 8.3 0.5 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAM19699.1 - 0.028 14.3 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 GAM19699.1 - 0.046 13.5 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAM19699.1 - 0.059 13.6 1.1 0.32 11.2 0.6 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAM19699.1 - 0.13 12.4 0.0 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3600 PF12207.8 GAM19699.1 - 0.14 12.1 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) AAA_13 PF13166.6 GAM19699.1 - 0.15 10.7 1.1 7.5 5.1 0.0 3.3 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 GAM19699.1 - 0.17 12.3 0.2 5.6 7.4 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 GAM19699.1 - 0.22 11.1 0.5 2.8 7.5 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Vps55 PF04133.14 GAM19700.1 - 2.6e-33 114.5 8.3 2.9e-33 114.3 8.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Ifi-6-16 PF06140.13 GAM19700.1 - 0.0072 16.2 2.8 0.013 15.4 2.8 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family MHYT PF03707.16 GAM19700.1 - 0.045 13.9 0.8 0.045 13.9 0.8 2.2 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Phage_holin_3_6 PF07332.11 GAM19700.1 - 0.059 13.4 0.1 0.059 13.4 0.1 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III mRNA_cap_enzyme PF01331.19 GAM19701.1 - 9.8e-33 113.6 0.1 2e-32 112.6 0.1 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 GAM19701.1 - 1.5e-13 51.4 0.9 1.5e-13 51.4 0.9 2.1 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain mRNA_triPase PF02940.15 GAM19701.1 - 3.8e-13 49.7 1.5 6e-11 42.5 0.6 2.7 2 0 0 2 2 2 2 mRNA capping enzyme, beta chain DNA_ligase_A_M PF01068.21 GAM19701.1 - 7.2e-07 29.0 0.0 0.0084 15.8 0.0 3.1 2 1 1 3 3 3 2 ATP dependent DNA ligase domain Pox_ATPase-GT PF10640.9 GAM19701.1 - 0.00029 19.8 1.0 0.00029 19.8 1.0 2.3 1 1 0 2 2 2 1 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase CDK2AP PF09806.9 GAM19701.1 - 0.81 9.7 7.7 2.1 8.3 7.7 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Membr_traf_MHD PF10540.9 GAM19701.1 - 1.3 9.2 4.2 18 5.4 0.4 2.3 2 0 0 2 2 2 0 Munc13 (mammalian uncoordinated) homology domain PTE PF02126.18 GAM19702.1 - 1.7e-83 280.5 1.0 2e-83 280.3 1.0 1.1 1 0 0 1 1 1 1 Phosphotriesterase family Rhomboid PF01694.22 GAM19703.1 - 2.9e-11 43.6 17.3 9.5e-10 38.7 17.3 2.7 1 1 0 1 1 1 1 Rhomboid family ABC_tran PF00005.27 GAM19704.1 - 6e-41 140.2 0.1 5.7e-20 72.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 GAM19704.1 - 1.8e-24 87.1 6.6 1.9e-05 24.6 0.0 4.4 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM19704.1 - 1.1e-12 47.9 0.7 1.5e-07 31.1 0.0 3.8 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAM19704.1 - 7e-10 39.5 4.7 3.4e-05 24.3 0.1 3.0 2 1 1 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 GAM19704.1 - 3e-09 37.3 0.2 9.1e-05 22.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 GAM19704.1 - 3.6e-08 33.0 0.0 0.0082 15.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 GAM19704.1 - 1.5e-07 31.5 0.0 0.0029 17.4 0.0 3.2 4 0 0 4 4 3 2 AAA ATPase domain NACHT PF05729.12 GAM19704.1 - 2.4e-07 30.8 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 NACHT domain ATP-synt_ab PF00006.25 GAM19704.1 - 5.9e-07 29.4 0.0 0.00045 19.9 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 GAM19704.1 - 7.1e-07 29.3 0.0 0.0066 16.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM19704.1 - 9.3e-07 28.9 0.1 0.0015 18.6 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 GAM19704.1 - 2.2e-06 27.3 0.0 0.0094 15.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 GAM19704.1 - 4.6e-06 27.3 8.3 0.003 18.1 0.5 3.3 3 1 1 4 4 3 2 AAA domain AAA_28 PF13521.6 GAM19704.1 - 1.3e-05 25.5 2.2 0.036 14.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 GAM19704.1 - 2.4e-05 24.4 0.3 0.02 14.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 GAM19704.1 - 2.5e-05 24.7 0.1 0.18 12.2 0.0 3.4 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 GAM19704.1 - 4.1e-05 22.5 0.3 0.052 12.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 GAM19704.1 - 5.6e-05 23.3 1.0 0.034 14.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 GAM19704.1 - 6.6e-05 22.7 0.0 0.54 9.9 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 GAM19704.1 - 7.4e-05 22.5 4.6 0.025 14.3 0.1 3.0 3 1 0 3 3 2 2 AAA domain TsaE PF02367.17 GAM19704.1 - 0.00013 22.0 0.1 0.38 10.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 GAM19704.1 - 0.00025 21.3 0.1 0.73 10.1 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 GAM19704.1 - 0.00033 19.7 0.1 0.37 9.7 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 GAM19704.1 - 0.0004 20.1 0.1 0.32 10.7 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 GAM19704.1 - 0.00059 19.5 0.7 0.65 9.6 0.1 2.9 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 GAM19704.1 - 0.00093 18.4 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 GAM19704.1 - 0.0012 19.4 0.7 2.7 8.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 GAM19704.1 - 0.0012 18.4 0.8 1.3 8.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain MobB PF03205.14 GAM19704.1 - 0.002 18.0 0.0 0.98 9.3 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 GAM19704.1 - 0.0038 17.1 0.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 GAM19704.1 - 0.0039 17.6 0.0 3 8.3 0.0 2.4 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 GAM19704.1 - 0.0039 16.4 0.0 0.92 8.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SbcCD_C PF13558.6 GAM19704.1 - 0.0055 16.9 0.7 0.81 10.0 0.0 3.3 4 0 0 4 4 2 1 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 GAM19704.1 - 0.0087 15.8 0.2 2.8 7.6 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein MCM PF00493.23 GAM19704.1 - 0.01 14.9 0.0 0.97 8.5 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain SRP54 PF00448.22 GAM19704.1 - 0.015 14.9 0.1 5.9 6.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Septin PF00735.18 GAM19704.1 - 0.027 13.7 0.1 3 7.0 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_14 PF13173.6 GAM19704.1 - 0.041 13.9 0.1 19 5.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 GAM19704.1 - 0.044 14.1 0.1 0.45 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAM19704.1 - 0.046 13.1 0.0 8.9 5.6 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ABC_tran_Xtn PF12848.7 GAM19704.1 - 0.048 13.7 5.5 0.024 14.6 3.2 1.7 2 0 0 2 2 1 0 ABC transporter Thymidylate_kin PF02223.17 GAM19704.1 - 0.051 13.2 0.3 1.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase DUF2813 PF11398.8 GAM19704.1 - 0.054 12.7 0.0 2 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) FeoB_N PF02421.18 GAM19704.1 - 0.056 13.0 0.1 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 GAM19704.1 - 0.056 12.6 0.0 8.8 5.4 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit AAA_27 PF13514.6 GAM19704.1 - 0.07 12.7 1.6 7.2 6.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GAM19704.1 - 0.07 12.5 0.1 1.5 8.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.18 GAM19704.1 - 0.08 12.7 0.0 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 GAM19704.1 - 0.084 12.8 0.0 4 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PIN7 PF18475.1 GAM19704.1 - 0.085 13.5 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 PIN domain DUF3243 PF11588.8 GAM19704.1 - 0.11 12.8 0.1 0.31 11.4 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF3243) KAP_NTPase PF07693.14 GAM19704.1 - 0.12 11.6 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain DLIC PF05783.11 GAM19704.1 - 0.12 11.1 0.1 5.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) DAP3 PF10236.9 GAM19704.1 - 0.15 11.2 0.2 18 4.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Zeta_toxin PF06414.12 GAM19704.1 - 0.16 11.2 5.2 4.9 6.4 0.1 3.3 3 0 0 3 3 3 0 Zeta toxin Dynamin_N PF00350.23 GAM19704.1 - 0.2 11.7 2.8 1.7 8.7 0.1 2.7 3 0 0 3 3 2 0 Dynamin family DUF87 PF01935.17 GAM19704.1 - 2.5 8.1 4.3 4.1 7.4 0.0 2.9 3 1 1 4 4 3 0 Helicase HerA, central domain DUF3584 PF12128.8 GAM19704.1 - 4.5 4.6 15.4 0.41 8.1 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) Peptidase_M8 PF01457.16 GAM19705.1 - 1.7e-62 211.8 1.3 3.2e-62 210.9 1.3 1.4 1 1 0 1 1 1 1 Leishmanolysin Kelch_6 PF13964.6 GAM19706.1 - 9.9e-08 32.0 4.3 0.14 12.5 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM19706.1 - 3e-07 30.3 4.4 0.32 11.0 0.1 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain zf-B_box PF00643.24 GAM19706.1 - 3.1e-05 24.0 1.6 6.5e-05 23.0 1.6 1.5 1 0 0 1 1 1 1 B-box zinc finger Kelch_2 PF07646.15 GAM19706.1 - 0.00024 21.0 2.8 0.031 14.3 0.0 4.3 4 0 0 4 4 4 1 Kelch motif COG4 PF08318.12 GAM19706.1 - 0.0054 15.9 1.5 0.0084 15.2 1.5 1.3 1 0 0 1 1 1 1 COG4 transport protein Kelch_5 PF13854.6 GAM19706.1 - 0.0067 16.4 6.6 0.034 14.2 0.2 3.3 4 0 0 4 4 4 1 Kelch motif PIN_8 PF18476.1 GAM19706.1 - 0.02 14.8 3.3 0.031 14.1 3.3 1.2 1 0 0 1 1 1 0 PIN like domain Kelch_1 PF01344.25 GAM19706.1 - 0.28 10.8 12.3 2.3 7.9 0.1 4.9 5 1 0 5 5 5 0 Kelch motif Peptidase_M8 PF01457.16 GAM19707.1 - 9e-74 249.0 11.0 2.7e-73 247.4 7.3 2.0 2 0 0 2 2 2 2 Leishmanolysin DUF4953 PF16313.5 GAM19707.1 - 0.045 12.9 0.1 0.077 12.2 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Herpes_U5 PF05999.11 GAM19708.1 - 0.00048 19.0 0.6 0.00074 18.4 0.4 1.4 1 1 1 2 2 2 1 Herpesvirus U5-like family Fzo_mitofusin PF04799.13 GAM19708.1 - 0.0096 15.5 1.2 0.013 15.1 0.5 1.5 1 1 1 2 2 2 1 fzo-like conserved region DUF4618 PF15397.6 GAM19708.1 - 0.013 15.0 5.4 0.022 14.2 5.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) HisKA_3 PF07730.13 GAM19708.1 - 0.018 15.5 0.0 0.061 13.8 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase Nbl1_Borealin_N PF10444.9 GAM19708.1 - 0.023 14.3 0.3 0.22 11.2 0.1 2.6 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal THP2 PF09432.10 GAM19708.1 - 0.035 14.2 5.4 0.077 13.1 4.3 1.9 1 1 1 2 2 2 0 Tho complex subunit THP2 BLOC1_2 PF10046.9 GAM19708.1 - 0.042 14.2 1.3 0.042 14.2 1.3 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 GAM19708.1 - 0.15 12.3 10.3 0.39 10.9 10.3 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DLP_helical PF18709.1 GAM19708.1 - 0.16 11.1 4.3 0.23 10.6 4.3 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain DUF4515 PF14988.6 GAM19708.1 - 0.72 9.6 8.7 4.2 7.2 1.8 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4515) O-antigen_lig PF13425.6 GAM19708.1 - 7.8 5.2 6.5 9.4 4.9 6.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Thioredoxin PF00085.20 GAM19709.1 - 5.9e-27 93.7 0.0 4.5e-26 90.8 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 GAM19709.1 - 7.5e-08 32.5 0.7 4.5e-07 30.0 0.4 2.4 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 GAM19709.1 - 2.2e-06 28.1 0.1 4.4e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAM19709.1 - 0.01 16.1 0.1 3.8 7.9 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin-like Defensin_big PF14862.6 GAM19709.1 - 1.3 9.4 3.4 2.1 8.7 0.0 2.8 3 0 0 3 3 3 0 Big defensin Peptidase_C1 PF00112.23 GAM19710.1 - 9.4e-66 222.0 6.8 1.3e-65 221.5 6.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM19710.1 - 6.4e-16 58.5 1.7 1.2e-15 57.6 1.7 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAM19710.1 - 1e-08 34.4 1.0 0.0013 17.6 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family PB1 PF00564.24 GAM19711.1 - 0.0037 17.2 0.1 0.0076 16.2 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Pex16 PF08610.10 GAM19713.1 - 1.3e-53 182.3 0.7 1.8e-53 181.8 0.7 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SSXT PF05030.12 GAM19714.1 - 4.9e-15 54.9 4.0 4.9e-15 54.9 4.0 2.6 2 0 0 2 2 2 1 SSXT protein (N-terminal region) Myb_DNA-binding PF00249.31 GAM19715.1 - 5e-11 42.6 0.1 8.4e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain CH PF00307.31 GAM19716.1 - 3.7e-15 56.0 0.0 1.4e-14 54.2 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM19716.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Ank_2 PF12796.7 GAM19717.1 - 1.3e-26 93.0 16.7 7.9e-09 36.0 0.7 4.9 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19717.1 - 2.7e-26 91.6 8.1 2.5e-05 24.7 0.1 7.3 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM19717.1 - 7.2e-19 67.6 8.8 0.011 16.1 0.1 9.0 2 2 7 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19717.1 - 5.2e-18 63.3 4.3 1.2 9.9 0.0 9.4 7 1 2 9 9 9 4 Ankyrin repeat DUF5049 PF16468.5 GAM19717.1 - 1.4e-05 24.9 2.5 12 5.9 0.0 6.9 5 3 4 9 9 9 2 Domain of unknown function (DUF5049) Ank PF00023.30 GAM19717.1 - 0.00058 20.2 10.5 12 6.6 0.0 7.3 6 2 1 7 7 7 1 Ankyrin repeat TIG PF01833.24 GAM19718.1 - 3.5e-55 184.0 97.7 9.9e-13 48.0 5.6 14.8 14 1 0 14 14 14 11 IPT/TIG domain DNase_II PF03265.15 GAM19718.1 - 2.4e-26 92.8 1.0 1e-14 54.6 0.9 2.5 2 0 0 2 2 2 2 Deoxyribonuclease II SdrD_B PF17210.3 GAM19718.1 - 0.042 14.1 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 SdrD B-like domain Coiled PF05710.12 GAM19719.1 - 0.0071 17.1 5.2 0.0094 16.8 5.2 1.2 1 0 0 1 1 1 1 Coiled coil Goodbye PF17109.5 GAM19719.1 - 0.73 10.3 2.1 17 5.9 0.1 2.0 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain CAP PF00188.26 GAM19720.1 - 1.6e-15 58.1 0.4 5.2e-15 56.4 0.4 1.9 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF1842 PF08896.10 GAM19720.1 - 0.0055 17.0 2.7 0.61 10.4 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF1842) TFIIA PF03153.13 GAM19720.1 - 5.7 6.8 21.8 7.4 6.5 21.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.13 GAM19720.1 - 5.8 5.4 21.9 7.5 5.0 21.9 1.2 1 0 0 1 1 1 0 Utp14 protein Kelch_6 PF13964.6 GAM19721.1 - 8.2e-10 38.6 6.3 1.8e-05 24.8 0.0 4.9 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM19721.1 - 3.6e-06 26.9 1.6 1e-05 25.4 0.0 2.7 4 0 0 4 4 4 1 Galactose oxidase, central domain zf-B_box PF00643.24 GAM19721.1 - 6.4e-06 26.2 8.8 2.8e-05 24.2 8.8 2.1 1 0 0 1 1 1 1 B-box zinc finger Snapin_Pallidin PF14712.6 GAM19721.1 - 0.092 13.2 3.1 0.55 10.7 1.2 2.7 2 0 0 2 2 2 0 Snapin/Pallidin Kelch_3 PF13415.6 GAM19721.1 - 0.096 13.0 0.7 3.1 8.2 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM19721.1 - 0.33 10.6 8.4 0.34 10.5 0.0 4.2 3 1 0 3 3 3 0 Kelch motif DUF3502 PF12010.8 GAM19722.1 - 0.076 13.7 0.2 0.094 13.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) HARE-HTH PF05066.13 GAM19722.1 - 0.19 12.2 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain WD40 PF00400.32 GAM19725.1 - 5.9e-29 99.7 27.3 2.2e-06 28.3 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM19725.1 - 1.4e-10 41.3 4.7 0.0067 16.7 0.0 4.1 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM19725.1 - 2.1e-07 30.0 8.9 0.0036 16.0 0.7 4.4 1 1 2 4 4 4 4 Nucleoporin Nup120/160 DUF1513 PF07433.11 GAM19725.1 - 0.0026 16.9 0.4 0.22 10.6 0.0 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF1513) TetM_leader PF08076.11 GAM19725.1 - 0.83 9.5 2.8 39 4.1 0.2 3.2 3 0 0 3 3 3 0 Tetracycline resistance determinant leader peptide zf-RING_2 PF13639.6 GAM19726.1 - 1.5e-11 44.4 7.0 1.5e-11 44.4 7.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM19726.1 - 1.1e-08 34.8 6.4 1.1e-08 34.8 6.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 GAM19726.1 - 1.9e-08 34.4 4.8 1.9e-08 34.4 4.8 2.2 2 0 0 2 2 2 1 zinc-ribbon zf-RING_11 PF17123.5 GAM19726.1 - 5.1e-08 32.5 6.1 5.5e-08 32.4 3.7 2.3 2 0 0 2 2 2 1 RING-like zinc finger SUIM_assoc PF16619.5 GAM19726.1 - 5e-06 26.5 4.0 5e-06 26.5 4.0 4.4 4 1 1 5 5 2 1 Unstructured region C-term to UIM in Ataxin3 zf-RING_5 PF14634.6 GAM19726.1 - 2e-05 24.4 3.9 2e-05 24.4 3.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAM19726.1 - 2.1e-05 24.7 8.8 2.1e-05 24.7 8.8 3.1 2 2 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAM19726.1 - 8.1e-05 22.4 6.7 8.1e-05 22.4 6.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM19726.1 - 8.6e-05 22.3 10.9 0.00078 19.2 3.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) NinG PF05766.12 GAM19726.1 - 9.7e-05 22.4 0.8 9.7e-05 22.4 0.8 2.7 2 1 0 2 2 2 1 Bacteriophage Lambda NinG protein zf-RING_UBOX PF13445.6 GAM19726.1 - 0.00011 22.1 2.6 0.00011 22.1 2.6 2.9 3 1 0 3 3 2 1 RING-type zinc-finger DUF2722 PF10846.8 GAM19726.1 - 0.00013 21.1 2.6 0.00013 21.1 2.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) HypA PF01155.19 GAM19726.1 - 0.00013 22.0 8.2 0.007 16.4 0.5 2.6 2 1 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_4 PF14447.6 GAM19726.1 - 0.00046 20.0 4.0 0.00046 20.0 4.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 GAM19726.1 - 0.002 18.1 2.4 0.002 18.1 2.4 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAM19726.1 - 0.0057 16.3 3.4 0.0057 16.3 3.4 2.4 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type A2L_zn_ribbon PF08792.10 GAM19726.1 - 0.015 15.0 0.7 0.015 15.0 0.7 2.6 3 0 0 3 3 2 0 A2L zinc ribbon domain TFIIA PF03153.13 GAM19726.1 - 0.016 15.2 24.7 0.17 11.9 11.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BRF1 PF07741.13 GAM19726.1 - 0.019 15.3 3.8 0.57 10.6 0.0 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain EPL1 PF10513.9 GAM19726.1 - 0.039 14.3 0.3 0.039 14.3 0.3 2.5 3 0 0 3 3 2 0 Enhancer of polycomb-like Prok-RING_1 PF14446.6 GAM19726.1 - 0.05 13.5 14.5 0.47 10.4 1.6 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DZR PF12773.7 GAM19726.1 - 0.11 12.6 6.2 2.4 8.3 0.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon PTPRCAP PF15713.5 GAM19726.1 - 0.2 11.9 10.0 1.5 9.1 2.0 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Rad50_zn_hook PF04423.14 GAM19726.1 - 0.22 11.4 0.1 0.22 11.4 0.1 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif Suf PF05843.14 GAM19726.1 - 0.3 11.0 11.8 0.11 12.4 3.1 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 GAM19726.1 - 0.37 9.5 9.2 0.44 9.2 0.8 2.1 2 0 0 2 2 2 0 Presenilin Fer4_22 PF17179.4 GAM19726.1 - 0.41 11.5 5.9 0.41 11.5 0.7 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Dpy19 PF10034.9 GAM19726.1 - 0.43 8.7 2.1 0.46 8.6 0.2 1.7 2 0 0 2 2 2 0 Q-cell neuroblast polarisation zf-RING_4 PF14570.6 GAM19726.1 - 4.3 7.2 12.8 1.9 8.3 0.7 3.0 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Zip PF02535.22 GAM19726.1 - 5.7 6.1 8.4 0.98 8.6 0.6 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter IBR PF01485.21 GAM19726.1 - 7.6 6.8 11.8 0.91 9.8 0.6 3.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 GAM19726.1 - 8.7 6.6 14.0 0.5 10.5 1.1 3.2 2 1 0 2 2 2 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 GAM19726.1 - 9.8 6.2 14.8 0.14 12.1 3.6 3.3 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Peptidase_S10 PF00450.22 GAM19727.1 - 2.5e-109 366.5 3.5 3.2e-109 366.1 3.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase UL45 PF05473.12 GAM19727.1 - 0.21 11.2 0.1 0.36 10.4 0.1 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like UQ_con PF00179.26 GAM19728.1 - 1.8e-37 128.1 0.1 2.3e-37 127.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAM19728.1 - 0.21 11.9 2.7 0.36 11.1 1.4 2.1 1 1 1 2 2 2 0 RWD domain TPR_1 PF00515.28 GAM19729.1 - 0.0014 18.4 0.1 0.0033 17.2 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM19729.1 - 0.021 14.9 0.5 0.053 13.6 0.5 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 GAM19729.1 - 0.029 14.5 0.2 0.12 12.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4919 PF16266.5 GAM19729.1 - 0.033 14.1 0.1 0.077 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_12 PF13424.6 GAM19729.1 - 0.064 13.6 2.1 0.2 12.0 0.6 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Baculo_IE-1 PF05290.11 GAM19729.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) TPR_7 PF13176.6 GAM19729.1 - 0.13 12.3 0.5 0.38 10.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4766 PF15973.5 GAM19729.1 - 0.54 10.8 6.3 0.61 10.7 3.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4766) Ima1_N PF09779.9 GAM19730.1 - 1.5e-22 80.9 16.8 1.5e-22 80.9 16.8 2.2 2 0 0 2 2 2 1 Ima1 N-terminal domain SUIM_assoc PF16619.5 GAM19730.1 - 0.007 16.4 7.2 0.19 11.8 0.3 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF2719 PF10891.8 GAM19730.1 - 0.014 15.3 0.4 0.057 13.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2719) YABBY PF04690.13 GAM19730.1 - 8.5 6.9 9.1 3.6 8.1 0.2 2.4 2 0 0 2 2 2 0 YABBY protein CAP PF00188.26 GAM19731.1 - 7.8e-15 55.8 0.0 9e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Cysteine-rich secretory protein family UBA PF00627.31 GAM19732.1 - 1.2e-22 79.4 3.3 9.5e-12 44.6 1.2 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 GAM19732.1 - 2e-17 62.6 2.8 3.5e-17 61.9 2.8 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 GAM19732.1 - 1e-14 54.0 0.4 1.9e-14 53.2 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA_3 PF09288.10 GAM19732.1 - 2.6e-05 23.9 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD PF11976.8 GAM19732.1 - 0.00012 21.9 0.4 0.00029 20.6 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_2 PF08587.11 GAM19732.1 - 0.016 15.3 0.1 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) LolA PF03548.15 GAM19732.1 - 0.027 14.2 0.8 0.16 11.7 0.0 2.4 3 0 0 3 3 3 0 Outer membrane lipoprotein carrier protein LolA MCM_N PF14551.6 GAM19732.1 - 0.041 14.5 0.1 0.081 13.5 0.1 1.6 1 0 0 1 1 1 0 MCM N-terminal domain Ubiquitin_5 PF18037.1 GAM19732.1 - 0.065 13.6 1.0 0.2 12.0 0.5 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM19732.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CENP-B_dimeris PF09026.10 GAM19732.1 - 0.51 10.8 8.7 0.88 10.0 8.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAP PF07174.11 GAM19732.1 - 1.3 8.5 17.1 1.8 8.0 17.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Thioredoxin PF00085.20 GAM19733.1 - 6.5e-06 26.1 0.0 2.1e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin FERM_M PF00373.18 GAM19734.1 - 5.5e-21 75.2 0.2 1.4e-20 73.8 0.2 1.8 1 0 0 1 1 1 1 FERM central domain LRR_6 PF13516.6 GAM19734.1 - 1e-08 34.5 33.6 0.039 14.0 1.3 10.9 12 0 0 12 12 12 3 Leucine Rich repeat FERM_N PF09379.10 GAM19734.1 - 9.2e-06 25.5 0.0 2.7e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 FERM N-terminal domain LRR_1 PF00560.33 GAM19734.1 - 0.048 14.2 20.2 12 6.9 0.1 9.4 9 1 0 9 9 9 0 Leucine Rich Repeat Mitofilin PF09731.9 GAM19734.1 - 0.059 12.2 1.6 0.094 11.5 1.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LRR_4 PF12799.7 GAM19734.1 - 0.49 10.9 38.3 3.5 8.2 3.3 8.6 5 2 2 8 8 8 0 Leucine Rich repeats (2 copies) FBA_2 PF07735.17 GAM19734.1 - 0.83 9.8 11.7 0.016 15.3 2.6 3.0 3 0 0 3 3 3 0 F-box associated tRNA_Me_trans PF03054.16 GAM19735.1 - 4.2e-105 351.4 0.0 5e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 GAM19735.1 - 1.9e-05 24.3 0.0 8.1e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 GAM19735.1 - 2.4e-05 24.2 0.0 3.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 GAM19735.1 - 3.3e-05 23.1 0.0 0.00011 21.4 0.0 1.8 2 0 0 2 2 2 1 NAD synthase QueC PF06508.13 GAM19735.1 - 0.0039 16.7 0.0 0.014 14.9 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 GAM19735.1 - 0.0051 16.6 0.1 0.088 12.5 0.1 2.3 1 1 0 1 1 1 1 PP-loop family E1_dh PF00676.20 GAM19736.1 - 3e-64 216.9 0.0 4.1e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 GAM19736.1 - 1.3e-63 213.9 0.0 2.8e-63 212.8 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 GAM19736.1 - 1.6e-47 161.0 0.0 3e-47 160.1 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 GAM19736.1 - 3.3e-17 61.8 4.5 1e-16 60.2 4.5 1.9 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Cytokin_check_N PF10407.9 GAM19736.1 - 0.051 13.5 0.0 0.2 11.6 0.0 2.1 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus Coiled PF05710.12 GAM19737.1 - 1.8e-05 25.5 13.5 2.3e-05 25.1 13.5 1.1 1 0 0 1 1 1 1 Coiled coil DUF1388 PF07142.12 GAM19738.1 - 3.2 7.8 59.1 0.087 12.8 4.0 7.3 7 0 0 7 7 7 0 Repeat of unknown function (DUF1388) FNIP PF05725.12 GAM19739.1 - 1.3e-94 310.2 43.9 1.4e-13 50.7 0.7 12.8 6 3 5 13 13 13 11 FNIP Repeat Complex1_LYR PF05347.15 GAM19740.1 - 4e-11 42.8 1.2 4e-11 42.8 1.2 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAM19740.1 - 8.2e-08 32.9 0.4 1.6e-07 31.9 0.4 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Pyr_redox_2 PF07992.14 GAM19741.1 - 4.5e-36 124.6 0.2 5.8e-36 124.2 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM19741.1 - 1.4e-19 70.4 2.8 3.2e-12 46.8 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM19741.1 - 2.2e-10 40.7 0.0 0.0039 16.8 0.0 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAM19741.1 - 4.2e-10 39.4 0.5 3.2e-06 26.6 0.1 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM19741.1 - 5.6e-09 36.1 0.1 0.0044 17.2 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAM19741.1 - 1.1e-06 28.1 0.3 0.03 13.5 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 GAM19741.1 - 3.6e-06 26.7 0.1 0.0021 17.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) Trp_halogenase PF04820.14 GAM19741.1 - 5e-06 25.6 0.2 0.01 14.7 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase TrkA_N PF02254.18 GAM19741.1 - 2.7e-05 24.4 0.2 0.25 11.6 0.0 2.8 2 0 0 2 2 2 2 TrkA-N domain Lycopene_cycl PF05834.12 GAM19741.1 - 4.9e-05 22.6 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 GAM19741.1 - 9.6e-05 22.6 1.7 0.29 11.4 0.1 2.9 3 0 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain HI0933_like PF03486.14 GAM19741.1 - 0.00011 21.0 0.1 0.048 12.4 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_7 PF13241.6 GAM19741.1 - 0.00015 22.2 0.4 0.24 11.9 0.0 2.7 3 0 0 3 3 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 GAM19741.1 - 0.0004 19.8 0.1 0.7 9.1 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 GAM19741.1 - 0.0005 20.1 3.6 1.6 8.7 0.0 3.9 2 2 2 4 4 4 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 GAM19741.1 - 0.0011 18.9 0.0 0.51 10.2 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAM19741.1 - 0.0033 16.7 0.0 0.48 9.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.16 GAM19741.1 - 0.0074 15.9 0.1 1.1 8.9 0.1 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 GAM19741.1 - 0.014 14.5 0.0 3.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Spermine_synth PF01564.17 GAM19741.1 - 0.024 14.1 0.6 0.16 11.3 0.4 2.3 2 1 1 3 3 3 0 Spermine/spermidine synthase domain DUF2498 PF10692.9 GAM19741.1 - 0.032 14.1 0.1 3.6 7.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2498) RIBIOP_C PF04950.12 GAM19742.1 - 2.8e-100 335.5 0.0 2.8e-100 335.5 0.0 1.9 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAM19742.1 - 2.1e-15 56.6 0.0 1.3e-14 54.0 0.0 2.5 1 1 0 1 1 1 1 AARP2CN (NUC121) domain KAR9 PF08580.10 GAM19743.1 - 2.1 6.8 22.1 2.7 6.4 22.1 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RIFIN PF02009.16 GAM19743.1 - 2.3 8.0 5.5 3.3 7.5 5.5 1.3 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 GAM19743.1 - 3 7.2 12.5 8.7 5.6 13.0 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein GCOM2 PF15328.6 GAM19743.1 - 5.1 7.4 10.8 7.7 6.8 10.8 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF572 PF04502.13 GAM19743.1 - 7 6.2 12.5 9.6 5.7 12.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Presenilin PF01080.17 GAM19743.1 - 7.3 5.2 10.7 9.8 4.8 10.7 1.1 1 0 0 1 1 1 0 Presenilin Chondroitinas_B PF14592.6 GAM19744.1 - 0.0015 17.5 0.2 0.0016 17.4 0.2 1.0 1 0 0 1 1 1 1 Chondroitinase B Thioredoxin PF00085.20 GAM19745.1 - 6.6e-16 58.2 0.0 7.1e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 GAM19745.1 - 0.00071 19.4 0.0 0.0009 19.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 GAM19745.1 - 0.0073 16.2 0.0 0.0088 16.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 GAM19745.1 - 0.02 15.2 0.0 0.036 14.4 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 GAM19745.1 - 0.024 14.0 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 GAM19745.1 - 0.04 13.6 0.1 0.065 12.9 0.1 1.4 1 1 0 1 1 1 0 Redoxin His_Phos_2 PF00328.22 GAM19746.1 - 9.3e-22 77.9 0.0 1.1e-17 64.5 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) TIG PF01833.24 GAM19747.1 - 8.8e-12 45.0 31.9 2.1e-07 30.9 3.9 4.9 4 1 0 4 4 4 3 IPT/TIG domain Lectin_C PF00059.21 GAM19747.1 - 0.00098 19.8 0.4 0.0037 18.0 0.2 2.2 2 0 0 2 2 2 1 Lectin C-type domain I-EGF_1 PF18372.1 GAM19747.1 - 0.0025 17.8 4.5 0.0025 17.8 4.5 2.3 3 0 0 3 3 3 1 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 GAM19747.1 - 0.022 15.1 6.1 0.051 14.0 6.1 1.6 1 0 0 1 1 1 0 EGF-like domain DDA1 PF10172.9 GAM19747.1 - 0.024 14.9 0.3 0.08 13.2 0.3 1.9 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase hEGF PF12661.7 GAM19747.1 - 0.15 12.7 5.3 0.64 10.7 5.3 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 GAM19747.1 - 0.23 11.5 3.0 0.64 10.1 3.0 1.8 1 0 0 1 1 1 0 Tenascin EGF domain Raptor_N PF14538.6 GAM19748.1 - 0.11 12.4 1.0 0.49 10.3 1.0 2.2 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Profilin PF00235.19 GAM19749.1 - 5e-10 39.7 0.1 6.9e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Profilin ABC2_membrane PF01061.24 GAM19751.1 - 4.8e-39 134.0 24.8 8.4e-39 133.2 24.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAM19751.1 - 2.4e-29 102.6 0.0 5.1e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM19751.1 - 3.6e-07 30.3 2.3 0.0038 17.1 0.0 2.7 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAM19751.1 - 0.00029 20.5 0.1 0.00068 19.3 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.6 GAM19751.1 - 0.00043 20.0 0.0 0.0016 18.1 0.0 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM19751.1 - 0.00052 20.4 0.0 0.00092 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM19751.1 - 0.00095 19.1 0.0 0.0029 17.5 0.0 1.8 2 0 0 2 2 1 1 RsgA GTPase SMC_N PF02463.19 GAM19751.1 - 0.0012 18.3 0.0 0.2 11.1 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAM19751.1 - 0.0029 17.9 0.1 0.032 14.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain PDR_CDR PF06422.12 GAM19751.1 - 0.0039 17.1 0.2 0.013 15.4 0.2 1.9 1 0 0 1 1 1 1 CDR ABC transporter Rad17 PF03215.15 GAM19751.1 - 0.011 15.7 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 GAM19751.1 - 0.018 14.1 0.1 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 GAM19751.1 - 0.027 14.2 0.2 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GAM19751.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 GAM19751.1 - 0.039 13.9 0.4 12 5.8 0.0 2.9 3 0 0 3 3 3 0 NTPase AAA_18 PF13238.6 GAM19751.1 - 0.051 14.1 0.1 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAM19751.1 - 0.058 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 GAM19751.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAM19751.1 - 0.086 13.3 0.1 0.086 13.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain NAPRTase_C PF17956.1 GAM19751.1 - 0.098 13.1 0.2 0.17 12.3 0.2 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain AAA_28 PF13521.6 GAM19751.1 - 0.1 12.8 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain KIAA1430 PF13879.6 GAM19751.1 - 0.28 12.0 2.4 0.65 10.8 2.4 1.6 1 0 0 1 1 1 0 KIAA1430 homologue ABC2_membrane_3 PF12698.7 GAM19751.1 - 5.2 6.1 36.3 28 3.7 36.3 2.3 1 1 0 1 1 1 0 ABC-2 family transporter protein Proteasome PF00227.26 GAM19752.1 - 5.5e-50 169.5 0.0 6.7e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM19752.1 - 2.4e-10 39.9 0.2 4.1e-10 39.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Homeodomain PF00046.29 GAM19752.1 - 0.037 13.9 0.1 0.073 12.9 0.1 1.5 1 0 0 1 1 1 0 Homeodomain RNase_PH PF01138.21 GAM19753.1 - 8.2e-21 74.9 0.4 1.9e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAM19753.1 - 2.2e-09 37.2 0.4 1e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 DUF4196 PF13846.6 GAM19753.1 - 0.17 12.1 7.5 2.7 8.2 7.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) Rieske_3 PF18465.1 GAM19753.1 - 8.1 6.8 6.4 6.5 7.1 4.1 2.0 1 1 1 2 2 2 0 Rieske 3Fe-4S Copine PF07002.16 GAM19754.1 - 2.8e-65 219.8 0.2 4.4e-65 219.2 0.2 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 GAM19754.1 - 6.6e-24 84.2 0.0 7.9e-13 48.6 0.0 2.6 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GAM19754.1 - 1.4e-06 28.6 0.0 2.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus CDCA PF18484.1 GAM19754.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat 7tm_3 PF00003.22 GAM19755.1 - 5e-33 114.8 29.5 9.3e-33 113.9 29.5 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Beta_helix PF13229.6 GAM19755.1 - 0.0002 21.3 32.0 0.022 14.6 10.6 3.5 1 1 2 3 3 3 3 Right handed beta helix region Chlam_PMP PF02415.17 GAM19755.1 - 2.2 8.9 0.0 2.2 8.9 0.0 7.1 8 0 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat EGF_2 PF07974.13 GAM19756.1 - 3.8e-06 27.1 43.3 0.00072 19.9 10.9 3.9 3 0 0 3 3 3 3 EGF-like domain TRP PF06011.12 GAM19756.1 - 0.0026 16.6 36.9 0.0079 15.0 28.6 3.7 1 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel DUF5527 PF17665.1 GAM19756.1 - 0.41 10.2 2.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5527) ABC_tran PF00005.27 GAM19757.1 - 1.3e-26 93.7 0.0 2.3e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAM19757.1 - 2.7e-25 89.2 27.4 4e-25 88.7 27.4 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAM19757.1 - 3.2e-11 43.6 0.7 3.6e-08 33.6 0.0 2.9 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 GAM19757.1 - 0.00012 21.6 18.1 0.00012 21.6 18.1 2.4 2 0 0 2 2 2 1 ABC-2 type transporter SMC_N PF02463.19 GAM19757.1 - 0.0015 18.0 0.3 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM19757.1 - 0.016 15.0 0.5 0.037 13.8 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM19757.1 - 0.41 11.1 2.0 0.32 11.5 0.3 1.7 2 0 0 2 2 2 0 AAA domain Ribosomal_S16 PF00886.19 GAM19758.1 - 0.099 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S16 Membrane_bind PF14564.6 GAM19759.1 - 1.4e-37 128.4 0.0 2.3e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Membrane binding Crystall_3 PF08964.10 GAM19759.1 - 5e-23 81.1 0.1 7.9e-23 80.4 0.1 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall_3 PF08964.10 GAM19760.1 - 2.1e-15 56.7 0.1 2.5e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall PF00030.19 GAM19760.1 - 0.021 15.0 0.0 0.025 14.8 0.0 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin Pkinase PF00069.25 GAM19761.1 - 6.6e-74 248.6 0.0 3.7e-73 246.1 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19761.1 - 3e-51 174.2 0.0 5.8e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM19761.1 - 0.00022 20.7 0.0 0.00043 19.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM19761.1 - 0.00091 18.6 0.1 0.0024 17.3 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5578 PF17741.1 GAM19761.1 - 0.0015 18.0 0.2 0.0091 15.5 0.1 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5578) Arm PF00514.23 GAM19761.1 - 0.005 16.8 2.8 7 6.9 0.1 5.0 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RIO1 PF01163.22 GAM19761.1 - 0.013 15.1 0.1 0.032 13.8 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Ribosomal_60s PF00428.19 GAM19761.1 - 0.053 14.1 1.1 0.18 12.4 1.1 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein VF530 PF09905.9 GAM19761.1 - 0.059 13.6 0.3 0.39 10.9 0.1 2.3 2 0 0 2 2 2 0 DNA-binding protein VF530 YtzH PF14165.6 GAM19761.1 - 0.6 10.5 6.5 6.8 7.2 0.1 4.0 3 0 0 3 3 3 0 YtzH-like protein Sas10_Utp3 PF04000.15 GAM19762.1 - 1.9e-19 70.0 0.6 1.9e-19 70.0 0.6 3.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Sas10 PF09368.10 GAM19762.1 - 8e-17 61.5 9.6 8e-17 61.5 9.6 3.3 3 1 1 4 4 4 1 Sas10 C-terminal domain SPT6_acidic PF14632.6 GAM19762.1 - 0.0036 17.8 12.8 0.0036 17.8 12.8 5.8 2 2 3 5 5 5 1 Acidic N-terminal SPT6 NAF PF03822.14 GAM19762.1 - 0.045 13.9 0.1 0.17 12.1 0.1 2.0 1 0 0 1 1 1 0 NAF domain GYF PF02213.16 GAM19763.1 - 5.4e-08 32.4 0.3 1.5e-07 31.0 0.3 1.8 1 0 0 1 1 1 1 GYF domain adh_short PF00106.25 GAM19764.1 - 6e-47 159.6 0.4 8.1e-47 159.2 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM19764.1 - 7.4e-30 104.2 0.0 9.7e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM19764.1 - 5.9e-09 36.1 0.3 1.5e-08 34.8 0.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM19764.1 - 0.00098 18.7 0.0 0.0013 18.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM19764.1 - 0.0055 15.9 0.0 0.0085 15.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 GAM19764.1 - 0.04 13.5 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.19 GAM19764.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PsbM PF05151.12 GAM19764.1 - 0.11 12.3 0.3 0.22 11.3 0.3 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) SET PF00856.28 GAM19765.1 - 1.8e-19 70.7 0.4 1.8e-19 70.7 0.4 4.1 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.22 GAM19765.1 - 5.1e-08 32.6 0.0 1.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.9 GAM19765.1 - 3.4e-05 23.6 17.2 3.4e-05 23.6 17.2 3.4 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein DUF4407 PF14362.6 GAM19765.1 - 8.8 5.6 9.9 24 4.2 9.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SMK-1 PF04802.15 GAM19766.1 - 1.6e-65 220.5 10.4 1.6e-65 220.5 10.4 2.3 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 DUF966 PF06136.13 GAM19766.1 - 1.8 8.2 23.1 2.8 7.6 23.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CAP PF00188.26 GAM19767.1 - 7.5e-17 62.3 0.1 9.8e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family EMP70 PF02990.16 GAM19769.1 - 1.6e-83 281.2 14.7 1.5e-63 215.2 0.0 2.4 2 1 1 3 3 3 2 Endomembrane protein 70 STD1 PF17235.2 GAM19769.1 - 0.15 11.7 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 STD1/MTH1 LapA_dom PF06305.11 GAM19769.1 - 0.41 10.5 0.0 0.41 10.5 0.0 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EMP70 PF02990.16 GAM19770.1 - 4e-101 339.3 6.1 4e-101 339.3 6.1 1.4 1 1 0 1 1 1 1 Endomembrane protein 70 PAC4 PF16093.5 GAM19771.1 - 4.1e-08 33.3 0.1 5.3e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Proteasome PF00227.26 GAM19772.1 - 2e-44 151.4 0.0 2.2e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Laminin_G_3 PF13385.6 GAM19773.1 - 0.015 15.4 0.1 0.016 15.4 0.1 1.1 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Fusion_F0 PF13044.6 GAM19773.1 - 0.11 11.2 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus Coiled PF05710.12 GAM19773.1 - 8.8 7.2 16.9 13 6.7 16.9 1.4 1 1 0 1 1 1 0 Coiled coil WD40 PF00400.32 GAM19774.1 - 0.00024 21.8 5.5 12 7.0 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-UBP PF02148.19 GAM19774.1 - 2 8.8 6.7 5.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein Androgen_recep PF02166.16 GAM19774.1 - 2 7.1 11.6 0.71 8.7 2.7 2.1 2 0 0 2 2 2 0 Androgen receptor Pkinase PF00069.25 GAM19777.1 - 1.9e-73 247.1 0.0 2.7e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19777.1 - 2.1e-33 115.7 0.0 3.3e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM19777.1 - 1.8e-07 30.7 0.0 4.4e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAM19777.1 - 0.019 13.7 0.0 0.041 12.7 0.0 1.6 1 1 0 1 1 1 0 Fungal protein kinase YukC PF10140.9 GAM19777.1 - 0.062 12.1 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC FTA2 PF13095.6 GAM19777.1 - 0.073 12.7 0.1 10 5.7 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SIN1_PH PF16979.5 GAM19777.1 - 0.079 13.2 0.8 0.32 11.3 0.8 2.0 1 1 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TFIIA PF03153.13 GAM19777.1 - 1.2 9.1 5.9 2.5 8.0 5.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BRCA-2_OB1 PF09103.10 GAM19778.1 - 1.2e-40 138.3 0.3 3.9e-40 136.6 0.0 2.1 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 GAM19778.1 - 2.3e-14 53.5 3.4 2.8e-14 53.2 0.1 2.5 2 1 1 3 3 3 1 BRCA2, helical VWA PF00092.28 GAM19779.1 - 4e-06 27.2 0.3 8e-06 26.2 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Big_9 PF17963.1 GAM19779.1 - 5.9e-06 26.9 9.0 5.9e-06 26.9 9.0 7.6 7 1 0 7 7 7 3 Bacterial Ig domain Integrin_beta PF00362.18 GAM19779.1 - 0.031 13.9 0.3 0.11 12.2 0.2 1.8 1 1 1 2 2 2 0 Integrin beta chain VWA domain Cadherin_5 PF17892.1 GAM19779.1 - 1.9 8.5 12.5 0.021 14.8 1.7 3.4 4 0 0 4 4 4 0 Cadherin-like domain Laminin_EGF PF00053.24 GAM19779.1 - 6.7 6.9 20.8 1 9.6 4.2 2.4 1 1 1 2 2 2 0 Laminin EGF domain Kelch_6 PF13964.6 GAM19781.1 - 6e-10 39.1 8.8 8.9e-05 22.6 0.1 4.3 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 GAM19781.1 - 0.00018 21.0 14.1 0.051 13.2 0.0 4.9 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM19781.1 - 0.0063 16.5 13.3 0.41 10.7 0.2 5.2 5 1 0 5 5 5 2 Galactose oxidase, central domain DUF999 PF06198.11 GAM19781.1 - 0.029 14.4 0.2 0.084 12.9 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF999) Ribosomal_S17_N PF16205.5 GAM19781.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal Kelch_3 PF13415.6 GAM19781.1 - 0.18 12.1 2.1 13 6.2 0.0 4.2 5 0 0 5 5 5 0 Galactose oxidase, central domain Med4 PF10018.9 GAM19781.1 - 0.21 11.3 2.1 0.19 11.4 0.8 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1366 PF07104.11 GAM19781.1 - 0.67 9.7 4.2 0.19 11.4 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) Kelch_2 PF07646.15 GAM19781.1 - 7.7 6.7 9.8 40 4.4 1.8 4.4 4 1 0 4 4 4 0 Kelch motif Zip PF02535.22 GAM19782.1 - 6.9e-48 163.6 13.0 3.1e-47 161.4 13.0 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2970 PF11174.8 GAM19782.1 - 0.03 14.2 0.1 0.03 14.2 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2970) SLC35F PF06027.12 GAM19783.1 - 2.1e-99 332.8 28.3 2.6e-99 332.5 28.3 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 GAM19783.1 - 9.4e-12 45.3 35.8 1.8e-07 31.4 13.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 GAM19783.1 - 2e-08 33.6 15.4 2e-08 33.6 15.4 1.9 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 GAM19783.1 - 0.00039 19.7 24.0 0.00071 18.9 24.0 1.5 1 1 0 1 1 1 1 UAA transporter family Mg_trans_NIPA PF05653.14 GAM19783.1 - 0.003 16.7 5.0 0.003 16.7 5.0 2.2 1 1 1 2 2 2 1 Magnesium transporter NIPA Pex24p PF06398.11 GAM19783.1 - 4.4 6.2 7.2 7.1 5.5 4.1 2.3 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin SET PF00856.28 GAM19784.1 - 7.6e-08 32.9 0.0 1.4e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-C3HC4_3 PF13920.6 GAM19784.1 - 0.001 18.9 3.3 0.0019 18.0 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GAM19784.1 - 0.096 12.6 0.9 0.25 11.3 0.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TMCCDC2 PF15844.5 GAM19784.1 - 0.24 11.3 1.5 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 Pentapeptide_4 PF13599.6 GAM19786.1 - 1.2 9.4 5.4 22 5.3 3.3 3.5 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) Chlam_PMP PF02415.17 GAM19787.1 - 7.9e-10 38.6 35.3 0.014 15.8 0.2 9.4 10 0 0 10 10 10 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Insulin_TMD PF17870.1 GAM19787.1 - 0.014 15.5 0.8 0.036 14.1 0.8 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EGF PF00008.27 GAM19787.1 - 0.021 15.1 2.8 0.021 15.1 2.8 2.7 3 0 0 3 3 3 0 EGF-like domain DUF4448 PF14610.6 GAM19787.1 - 0.022 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CN_hydrolase PF00795.22 GAM19788.1 - 1.4e-16 60.6 0.0 2.3e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase G-patch_2 PF12656.7 GAM19789.1 - 2.8e-22 78.6 0.1 2.8e-22 78.6 0.1 2.1 2 0 0 2 2 2 1 G-patch domain KN17_SH3 PF18131.1 GAM19789.1 - 3.6e-13 49.4 0.4 8.9e-13 48.1 0.4 1.7 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain KOW PF00467.29 GAM19789.1 - 5.1e-10 38.9 3.6 0.002 18.0 0.3 3.6 3 0 0 3 3 3 3 KOW motif G-patch PF01585.23 GAM19789.1 - 1e-06 28.5 0.7 2.5e-06 27.3 0.7 1.7 1 0 0 1 1 1 1 G-patch domain DUF4537 PF15057.6 GAM19789.1 - 0.075 13.1 0.3 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Macoilin PF09726.9 GAM19789.1 - 0.26 9.8 9.4 0.74 8.3 3.8 2.2 2 0 0 2 2 2 0 Macoilin family GST_N_3 PF13417.6 GAM19790.1 - 1.8e-09 37.9 0.0 4.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM19790.1 - 1.5e-07 31.7 0.0 3.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM19790.1 - 6.8e-05 23.0 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM19790.1 - 0.00027 21.1 0.0 0.0013 18.9 0.0 2.1 2 2 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM19790.1 - 0.00033 20.9 0.0 0.00092 19.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM19790.1 - 0.0023 17.9 0.0 0.019 14.9 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAM19790.1 - 0.0064 16.3 0.0 0.037 13.8 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F_actin_bind PF08919.10 GAM19791.1 - 3e-09 37.0 0.3 6.2e-09 35.9 0.3 1.5 1 0 0 1 1 1 1 F-actin binding PH PF00169.29 GAM19792.1 - 3.1e-09 37.3 0.0 8.5e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 GAM19793.1 - 0.0021 18.4 2.7 0.88 10.3 0.1 4.7 5 0 0 5 5 5 1 Ankyrin repeat DUF3447 PF11929.8 GAM19793.1 - 0.041 13.9 6.6 0.2 11.6 0.1 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF3447) Ank_4 PF13637.6 GAM19793.1 - 0.19 12.3 1.8 7.1 7.3 0.1 4.0 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM19793.1 - 0.33 11.6 5.0 14 6.3 0.1 4.1 4 0 0 4 4 4 0 Ankyrin repeats (3 copies) MOR2-PAG1_C PF14225.6 GAM19794.1 - 1.3e-16 61.3 0.2 4.3e-16 59.6 0.2 2.0 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_N PF14222.6 GAM19794.1 - 4.9e-16 58.8 7.4 1.7e-10 40.5 0.0 3.2 3 1 0 3 3 3 2 Cell morphogenesis N-terminal RGS PF00615.19 GAM19794.1 - 4e-07 30.3 0.2 4e-07 30.3 0.2 3.7 5 0 0 5 5 5 1 Regulator of G protein signaling domain Imm2 PF14426.6 GAM19794.1 - 0.092 12.8 0.1 0.55 10.3 0.0 2.4 2 0 0 2 2 2 0 Immunity protein Imm2 Spt20 PF12090.8 GAM19794.1 - 0.69 9.5 18.8 0.13 11.8 13.9 2.3 2 0 0 2 2 2 0 Spt20 family GET2 PF08690.10 GAM19794.1 - 5.1 6.7 20.7 4.4 6.9 7.7 2.8 2 0 0 2 2 2 0 GET complex subunit GET2 GNAT_acetyltr_2 PF13718.6 GAM19794.1 - 6.6 6.1 6.4 6.3 6.1 1.6 3.0 3 0 0 3 3 3 0 GNAT acetyltransferase 2 Glyco_hydro_65m PF03632.15 GAM19795.1 - 2.6e-54 184.6 0.0 1.3e-45 155.9 0.5 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain DUF2152 PF10222.9 GAM19795.1 - 3.8e-15 55.3 0.0 2.8e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2152) Glyco_hydro_65C PF03633.15 GAM19795.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Glyco_hydro_65N PF03636.15 GAM19795.1 - 0.11 12.1 0.1 0.34 10.5 0.1 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Exonuc_VII_S PF02609.16 GAM19795.1 - 0.2 11.7 0.1 0.38 10.9 0.1 1.4 1 0 0 1 1 1 0 Exonuclease VII small subunit Citrate_bind PF16114.5 GAM19796.1 - 2.6e-84 281.1 0.0 3.7e-84 280.6 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 GAM19796.1 - 1.6e-15 57.2 0.1 6.9e-15 55.1 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain LOH1CR12 PF10158.9 GAM19797.1 - 0.00014 21.8 0.1 0.00014 21.8 0.1 1.8 2 0 0 2 2 2 1 Tumour suppressor protein Macoilin PF09726.9 GAM19797.1 - 0.17 10.4 14.0 0.23 10.0 14.0 1.2 1 0 0 1 1 1 0 Macoilin family DEAD PF00270.29 GAM19798.1 - 8.4e-42 142.9 0.1 2e-41 141.7 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM19798.1 - 5.9e-33 113.5 0.8 2.2e-30 105.3 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAM19798.1 - 8.7e-10 38.9 0.0 8.7e-10 38.9 0.0 3.0 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAM19798.1 - 0.0012 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF3444 PF11926.8 GAM19798.1 - 0.017 14.7 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) AAA_22 PF13401.6 GAM19798.1 - 0.025 14.8 0.3 0.12 12.7 0.3 2.0 1 1 0 1 1 1 0 AAA domain Terminase_6 PF03237.15 GAM19798.1 - 0.04 13.6 0.0 0.04 13.6 0.0 2.2 2 0 0 2 2 2 0 Terminase-like family Ank_2 PF12796.7 GAM19800.1 - 5.9e-05 23.6 0.3 0.00092 19.8 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19800.1 - 0.032 14.8 0.1 0.4 11.3 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19800.1 - 0.058 14.0 0.8 27 5.8 0.0 5.0 5 0 0 5 5 5 0 Ankyrin repeat ER PF01133.17 GAM19801.1 - 1e-37 128.1 0.9 2.3e-37 127.0 0.9 1.6 1 0 0 1 1 1 1 Enhancer of rudimentary TIG PF01833.24 GAM19802.1 - 4.3e-09 36.3 14.4 2e-07 31.0 5.5 2.4 1 1 1 2 2 2 2 IPT/TIG domain TMEM154 PF15102.6 GAM19802.1 - 0.00019 21.4 2.4 0.00044 20.2 2.1 1.7 1 1 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 GAM19802.1 - 0.00022 21.1 0.6 0.0003 20.6 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Protocadherin PF08374.11 GAM19802.1 - 0.0032 17.5 0.2 0.0058 16.6 0.2 1.5 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 GAM19802.1 - 0.011 16.6 0.2 0.027 15.4 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3377 PF11857.8 GAM19802.1 - 0.049 13.6 6.2 0.089 12.7 5.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) Sec66 PF09802.9 GAM19802.1 - 0.063 12.9 0.1 0.094 12.3 0.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 IMD PF08397.11 GAM19803.1 - 7.7e-16 58.1 5.6 1e-15 57.7 5.6 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_1 PF00018.28 GAM19803.1 - 1e-13 50.7 0.0 1.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM19803.1 - 1.3e-09 37.7 0.0 2.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM19803.1 - 3.8e-07 29.7 0.0 8.1e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 GAM19803.1 - 1.2e-05 25.2 6.0 1.2e-05 25.2 6.0 1.9 2 0 0 2 2 2 1 BAR domain of APPL family Cytochrom_B562 PF07361.11 GAM19803.1 - 0.027 15.1 3.5 0.084 13.5 3.5 1.9 1 0 0 1 1 1 0 Cytochrome b562 DUF4745 PF15923.5 GAM19803.1 - 0.065 13.2 0.2 0.44 10.5 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4745) TSC22 PF01166.18 GAM19803.1 - 0.77 10.1 9.3 0.071 13.4 1.8 3.1 3 1 1 4 4 4 0 TSC-22/dip/bun family Ribosomal_L38e PF01781.18 GAM19804.1 - 3.2e-26 91.2 4.1 4e-26 90.9 4.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF5630 PF18632.1 GAM19804.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5630) LIM PF00412.22 GAM19805.1 - 1e-10 41.6 3.3 2e-10 40.8 3.3 1.4 1 0 0 1 1 1 1 LIM domain zf-met PF12874.7 GAM19805.1 - 0.25 11.8 6.5 2.4 8.7 1.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type G8 PF10162.9 GAM19806.1 - 2.8e-21 75.8 0.1 6.6e-21 74.7 0.1 1.7 1 0 0 1 1 1 1 G8 domain EB PF01683.18 GAM19809.1 - 4e-05 23.8 1.4 4e-05 23.8 1.4 3.5 2 1 1 3 3 3 2 EB module EGF_2 PF07974.13 GAM19809.1 - 0.0037 17.6 10.1 0.0037 17.6 10.1 3.2 4 0 0 4 4 4 2 EGF-like domain EB PF01683.18 GAM19810.1 - 0.0039 17.4 7.2 0.0039 17.4 7.2 2.7 3 1 0 3 3 3 1 EB module Brr6_like_C_C PF10104.9 GAM19810.1 - 3.5 7.4 10.2 0.16 11.8 1.0 2.6 1 1 1 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain G8 PF10162.9 GAM19811.1 - 1.3e-19 70.4 0.1 3e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 G8 domain Ank_2 PF12796.7 GAM19812.1 - 3.6e-21 75.5 17.8 3.7e-07 30.7 0.2 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM19812.1 - 1.3e-15 57.2 7.9 0.0028 17.9 0.4 6.2 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM19812.1 - 1.9e-15 57.0 7.5 0.00013 22.5 0.1 5.2 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19812.1 - 7.5e-09 35.1 1.6 15 6.5 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 GAM19812.1 - 9.4e-05 22.7 0.0 21 5.8 0.0 5.9 2 1 2 4 4 4 1 Ankyrin repeat AhpC-TSA PF00578.21 GAM19812.1 - 0.089 12.7 0.0 20 5.1 0.0 3.1 1 1 1 3 3 3 0 AhpC/TSA family IES5 PF17335.2 GAM19813.1 - 0.019 15.2 0.4 0.022 15.0 0.4 1.1 1 0 0 1 1 1 0 Ino80 complex subunit 5 Syntaxin_2 PF14523.6 GAM19813.1 - 0.13 12.6 2.9 0.17 12.3 2.7 1.2 1 1 0 1 1 1 0 Syntaxin-like protein YuiB PF14068.6 GAM19814.1 - 0.068 13.8 3.3 0.072 13.7 3.3 1.1 1 0 0 1 1 1 0 Putative membrane protein DUF3487 PF11990.8 GAM19814.1 - 4.7 7.1 6.1 5.5 6.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) SdrD_B PF17210.3 GAM19816.1 - 7.7e-19 68.0 20.0 9.3e-07 29.1 0.1 6.5 5 3 1 6 6 6 4 SdrD B-like domain IL13 PF03487.13 GAM19816.1 - 0.069 12.9 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Interleukin-13 Dymeclin PF09742.9 GAM19817.1 - 9.1e-81 272.1 21.1 1.1e-80 271.8 21.1 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 GAM19817.1 - 0.00022 19.5 30.9 0.0098 14.1 0.7 4.0 3 1 1 4 4 4 3 High-temperature-induced dauer-formation protein DUF1084 PF06454.11 GAM19818.1 - 1.8e-09 37.4 21.8 3.8e-09 36.3 21.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF3810 PF12725.7 GAM19818.1 - 0.12 11.6 8.9 0.043 13.1 1.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) tRNA-synt_2b PF00587.25 GAM19819.1 - 1.5e-27 96.7 0.0 4.9e-27 95.0 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAM19819.1 - 4.2e-13 49.5 7.0 6.5e-13 48.9 7.0 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain SKG6 PF08693.10 GAM19820.1 - 0.003 16.9 2.8 0.0079 15.6 2.8 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 GAM19820.1 - 0.0034 17.4 1.1 0.014 15.4 1.1 2.1 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DUF3377 PF11857.8 GAM19820.1 - 0.058 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEMspv1-c74-12 PF11044.8 GAM19820.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Phage_spike PF18715.1 GAM19820.1 - 0.13 12.4 7.2 7 6.8 0.3 4.1 3 1 1 4 4 4 0 Phage spike trimer DUF4448 PF14610.6 GAM19820.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) RIFIN PF02009.16 GAM19820.1 - 0.34 10.8 1.1 0.43 10.4 0.1 1.6 2 0 0 2 2 2 0 Rifin Mito_carr PF00153.27 GAM19821.1 - 4.6e-66 218.8 6.3 5.5e-24 83.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PH PF00169.29 GAM19822.1 - 4.9e-07 30.2 0.7 1.1e-06 29.0 0.7 1.7 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 GAM19822.1 - 0.0056 16.5 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3510 PF12022.8 GAM19822.1 - 0.038 14.4 0.1 0.61 10.5 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) IF4E PF01652.18 GAM19823.1 - 2.5e-53 180.1 1.1 3.9e-53 179.5 1.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Dicty_REP PF05086.12 GAM19823.1 - 0.0012 17.0 10.7 0.0014 16.7 10.7 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Suf PF05843.14 GAM19823.1 - 0.18 11.7 5.7 0.21 11.5 5.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 GAM19823.1 - 0.56 10.9 11.4 0.83 10.3 11.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RP-C_C PF11800.8 GAM19823.1 - 0.86 9.7 8.7 1.2 9.2 8.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region MecA PF05389.12 GAM19823.1 - 0.9 9.1 8.4 1.8 8.1 8.5 1.4 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) ALMT PF11744.8 GAM19823.1 - 1.1 8.1 9.9 1.2 7.8 9.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 GAM19823.1 - 1.4 8.0 4.1 1.7 7.8 4.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Tmemb_cc2 PF10267.9 GAM19823.1 - 1.7 7.7 13.2 2.5 7.2 13.2 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Menin PF05053.13 GAM19823.1 - 1.8 6.8 14.0 2.4 6.4 14.0 1.1 1 0 0 1 1 1 0 Menin FSA_C PF10479.9 GAM19823.1 - 3.7 5.6 16.7 1.7 6.6 14.1 1.7 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Presenilin PF01080.17 GAM19823.1 - 3.7 6.2 11.8 4.8 5.9 11.8 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_M16_C PF05193.21 GAM19824.1 - 7.9e-28 97.7 0.0 3.4e-27 95.7 0.1 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAM19824.1 - 3.1e-25 88.9 0.0 6.7e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Retinal PF15449.6 GAM19824.1 - 0.15 9.8 8.8 0.19 9.4 8.8 1.2 1 0 0 1 1 1 0 Retinal protein LPP20 PF02169.16 GAM19824.1 - 8.7 6.8 9.3 2.8 8.4 3.9 2.6 2 0 0 2 2 2 0 LPP20 lipoprotein Dicty_CTDC PF00526.18 GAM19825.1 - 9.1e-08 31.9 21.3 4.5e-05 23.3 9.2 12.4 13 1 0 13 13 13 5 Dictyostelium (slime mold) repeat PA14 PF07691.12 GAM19825.1 - 2.6e-07 30.6 0.0 2.6e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 PA14 domain EGF_2 PF07974.13 GAM19826.1 - 7.3e-10 39.0 52.9 6.5e-05 23.2 12.9 3.5 3 0 0 3 3 3 3 EGF-like domain EGF PF00008.27 GAM19826.1 - 0.0076 16.5 9.7 0.0076 16.5 9.7 4.2 4 0 0 4 4 4 1 EGF-like domain Sporozoite_P67 PF05642.11 GAM19826.1 - 0.16 10.1 1.7 0.23 9.5 1.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen EGF_Tenascin PF18720.1 GAM19826.1 - 0.39 10.8 34.9 0.33 11.0 9.1 3.7 3 0 0 3 3 3 0 Tenascin EGF domain FNIP PF05725.12 GAM19827.1 - 3.2e-60 200.1 41.2 9.5e-14 51.3 0.8 9.0 5 3 5 10 10 10 9 FNIP Repeat FNIP PF05725.12 GAM19828.1 - 1.1e-28 99.1 9.6 3.8e-10 39.8 0.1 3.5 1 1 0 3 3 3 3 FNIP Repeat FNIP PF05725.12 GAM19829.1 - 6.8e-57 189.4 36.9 4.7e-11 42.7 0.2 9.9 6 2 5 11 11 11 10 FNIP Repeat GPI-anchored PF10342.9 GAM19830.1 - 0.0024 18.6 0.8 0.0058 17.4 0.8 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PCC_BT PF18140.1 GAM19830.1 - 0.043 14.1 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain Inhibitor_I67 PF11405.8 GAM19830.1 - 0.078 13.2 0.7 4.1 7.7 0.1 2.6 2 0 0 2 2 2 0 Bromelain inhibitor VI PPE PF00823.19 GAM19830.1 - 0.1 12.7 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 PPE family Crisp PF08562.10 GAM19830.1 - 8.6 7.0 10.6 6.1 7.5 3.7 3.1 3 0 0 3 3 3 0 Crisp 2-Hacid_dh_C PF02826.19 GAM19831.1 - 3e-50 170.1 0.0 6.2e-50 169.0 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM19831.1 - 3e-34 117.5 0.0 4.1e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAM19831.1 - 0.0001 22.5 0.1 0.00024 21.3 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 GAM19831.1 - 0.0029 17.3 0.1 0.025 14.4 0.0 2.4 2 0 0 2 2 2 1 ACT domain XdhC_C PF13478.6 GAM19831.1 - 0.0044 17.5 0.0 0.017 15.6 0.0 1.9 2 0 0 2 2 2 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 GAM19831.1 - 0.0058 16.7 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 GAM19831.1 - 0.014 15.0 0.0 0.054 13.1 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 GAM19831.1 - 0.028 14.3 0.0 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAP2 PF01569.21 GAM19832.1 - 3.8e-11 42.9 5.5 3.8e-11 42.9 5.5 2.5 3 1 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 GAM19832.1 - 8.5e-05 22.3 6.5 8.5e-05 22.3 6.5 2.4 2 0 0 2 2 2 1 PAP2 superfamily Polysacc_synt_3 PF13440.6 GAM19832.1 - 0.013 14.7 4.6 0.012 14.8 3.1 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein SAPS PF04499.15 GAM19833.1 - 8.1e-69 232.7 2.0 2.5e-41 142.0 0.1 2.4 1 1 1 2 2 2 2 SIT4 phosphatase-associated protein EF1_GNE PF00736.19 GAM19833.1 - 9.7e-30 102.6 0.8 2.3e-29 101.4 0.8 1.7 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain MobC PF05713.11 GAM19833.1 - 0.33 11.4 1.3 0.95 10.0 0.2 2.4 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) Sgf11 PF08209.11 GAM19834.1 - 2.3e-10 39.9 0.2 2.3e-10 39.9 0.2 1.7 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) SCA7 PF08313.12 GAM19834.1 - 2e-05 24.4 0.9 6.8e-05 22.7 0.9 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain SPA PF08616.10 GAM19836.1 - 7.3e-13 48.5 0.1 1.3e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 GAM19836.1 - 4.1e-10 38.9 0.4 0.00021 20.1 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.9 GAM19836.1 - 9.6e-10 38.5 0.9 1.5e-09 37.9 0.2 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 GAM19836.1 - 0.0017 18.3 0.1 0.0031 17.5 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Keratin_2_head PF16208.5 GAM19837.1 - 0.53 10.4 15.1 0.85 9.8 15.1 1.4 1 0 0 1 1 1 0 Keratin type II head Glycogen_syn PF05693.13 GAM19838.1 - 9e-268 890.1 0.0 9e-268 890.1 0.0 1.5 2 0 0 2 2 2 1 Glycogen synthase Glycos_transf_1 PF00534.20 GAM19838.1 - 3.9e-05 23.2 0.0 0.00039 20.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 GAM19838.1 - 0.00018 21.3 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 GAM19838.1 - 0.0057 16.7 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAM19838.1 - 0.012 16.0 0.0 0.13 12.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 Kelch_6 PF13964.6 GAM19839.1 - 5.1e-12 45.6 5.3 0.00015 22.0 0.1 4.7 3 1 1 4 4 4 4 Kelch motif DUF5074 PF16819.5 GAM19839.1 - 0.0027 17.7 0.0 0.061 13.4 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5074) Kelch_3 PF13415.6 GAM19839.1 - 0.018 15.3 2.8 2.9 8.3 0.1 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM19839.1 - 0.02 14.9 8.4 5.1 7.2 0.1 4.9 5 1 0 5 5 5 0 Galactose oxidase, central domain PAP2 PF01569.21 GAM19840.1 - 5.9e-07 29.3 3.1 5.9e-07 29.3 3.1 2.6 4 0 0 4 4 4 1 PAP2 superfamily Pkinase PF00069.25 GAM19841.1 - 7.1e-67 225.5 0.0 9.1e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19841.1 - 1.5e-48 165.4 0.1 2.6e-48 164.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase PH PF00169.29 GAM19841.1 - 5.7e-20 71.8 0.2 1.2e-19 70.7 0.2 1.6 1 0 0 1 1 1 1 PH domain PBD PF00786.28 GAM19841.1 - 1e-13 51.4 0.1 2.6e-13 50.1 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 GAM19841.1 - 1.6e-06 27.2 0.1 1.3e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase PH_8 PF15409.6 GAM19841.1 - 0.00026 21.2 0.2 0.00081 19.6 0.2 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 GAM19841.1 - 0.00039 19.8 0.1 0.0025 17.2 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAM19841.1 - 0.00085 18.4 0.1 0.0021 17.1 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain PH_17 PF18012.1 GAM19841.1 - 0.0017 18.1 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF1491 PF07372.12 GAM19841.1 - 0.025 14.9 0.0 0.068 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) PH_11 PF15413.6 GAM19841.1 - 0.17 12.3 8.4 1.1 9.7 5.4 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain APH PF01636.23 GAM19841.1 - 0.2 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HAD_2 PF13419.6 GAM19842.1 - 1.2e-13 51.5 0.0 2.2e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM19842.1 - 7.6e-10 39.4 0.0 1.2e-09 38.8 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM19842.1 - 9.8e-06 25.6 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PNK3P PF08645.11 GAM19842.1 - 9.8e-05 22.1 0.0 0.00058 19.6 0.0 2.0 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase 5_nucleotid PF05761.14 GAM19842.1 - 0.022 13.7 0.3 0.83 8.5 0.1 2.3 1 1 0 2 2 2 0 5' nucleotidase family Hydrolase_6 PF13344.6 GAM19842.1 - 0.023 14.8 0.2 0.17 12.0 0.0 2.6 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Kelch_6 PF13964.6 GAM19843.1 - 4e-16 58.7 3.3 2.8e-07 30.6 0.0 4.7 2 2 2 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAM19843.1 - 1.7e-11 43.9 2.8 6.3e-07 29.3 0.1 5.3 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM19843.1 - 1e-10 41.0 1.0 0.00021 20.8 0.0 4.2 4 0 0 4 4 4 3 Kelch motif zf-B_box PF00643.24 GAM19843.1 - 4.5e-09 36.3 5.3 1e-08 35.2 5.3 1.6 1 0 0 1 1 1 1 B-box zinc finger Kelch_2 PF07646.15 GAM19843.1 - 4.9e-08 32.6 0.0 0.0049 16.8 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 GAM19843.1 - 5.1e-07 29.8 1.2 0.017 15.4 0.0 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain GSH-S_ATP PF02955.16 GAM19843.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Cytomega_UL20A PF05984.12 GAM19844.1 - 1.3 9.3 4.5 4 7.8 4.4 1.9 1 1 0 1 1 1 0 Cytomegalovirus UL20A protein RRM_1 PF00076.22 GAM19845.1 - 1.7e-19 69.4 0.2 2.7e-12 46.3 0.1 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R2K_2 PF18299.1 GAM19845.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 RRM_occluded PF16842.5 GAM19845.1 - 0.17 11.8 0.0 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif ELMO_CED12 PF04727.13 GAM19848.1 - 2.3e-24 86.5 0.1 1.3e-23 84.1 0.0 2.3 2 0 0 2 2 2 1 ELMO/CED-12 family FNIP PF05725.12 GAM19849.1 - 3.7e-69 228.6 21.8 2.2e-13 50.2 0.1 8.0 6 1 3 9 9 9 9 FNIP Repeat Cullin_binding PF03556.15 GAM19850.1 - 1.1e-30 106.6 1.0 2.1e-30 105.7 1.0 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 GAM19850.1 - 1.7e-06 27.8 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain p25-alpha PF05517.12 GAM19850.1 - 0.0089 16.2 0.2 0.022 14.9 0.2 1.7 1 0 0 1 1 1 1 p25-alpha EF-hand_6 PF13405.6 GAM19850.1 - 0.061 13.3 0.2 5.6 7.2 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain RhoGEF PF00621.20 GAM19851.1 - 2.6e-41 141.9 7.7 3.8e-41 141.3 7.7 1.2 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 GAM19851.1 - 0.0016 18.4 0.1 0.0044 17.0 0.1 1.6 1 0 0 1 1 1 1 PH domain PH PF00169.29 GAM19851.1 - 0.0043 17.5 0.2 0.01 16.3 0.2 1.6 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 GAM19853.1 - 7.3e-06 26.5 0.1 0.51 11.0 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM19853.1 - 0.18 12.5 0.9 1.3e+02 3.7 0.0 5.4 7 0 0 7 7 7 0 Ankyrin repeat Ank_2 PF12796.7 GAM19855.1 - 1.2e-06 29.0 1.4 0.0041 17.7 0.2 4.4 3 3 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM19855.1 - 0.015 15.6 0.2 15 6.0 0.0 4.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF2509 PF10713.9 GAM19855.1 - 0.034 14.3 0.1 0.094 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) Ank_3 PF13606.6 GAM19855.1 - 0.051 14.2 2.0 8.9 7.3 0.1 5.4 7 0 0 7 7 7 0 Ankyrin repeat DUF1858 PF08984.11 GAM19855.1 - 0.054 13.7 0.0 1 9.6 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) Ank PF00023.30 GAM19855.1 - 0.1 13.1 0.7 9.9 6.8 0.1 3.4 3 0 0 3 3 3 0 Ankyrin repeat DUF4567 PF15131.6 GAM19856.1 - 0.025 14.6 0.0 1.2 9.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4567) Ank_2 PF12796.7 GAM19858.1 - 0.00017 22.1 0.2 0.13 12.8 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) STAR_dimer PF16544.5 GAM19858.1 - 0.019 14.5 0.0 1.4 8.5 0.0 3.4 3 0 0 3 3 3 0 Homodimerisation region of STAR domain protein Ank_3 PF13606.6 GAM19858.1 - 0.024 15.2 4.1 3.8 8.4 0.3 5.3 4 1 1 5 5 5 0 Ankyrin repeat Ank_4 PF13637.6 GAM19858.1 - 0.037 14.6 1.0 2.6 8.7 0.1 3.9 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM19860.1 - 0.0003 21.3 2.4 0.13 12.8 0.0 4.5 5 1 0 5 5 5 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM19860.1 - 0.013 16.0 1.6 5.1 8.0 0.0 5.1 5 0 0 5 5 5 0 Ankyrin repeat DnaJ-X PF14308.6 GAM19860.1 - 0.097 12.1 0.3 5.6 6.3 0.1 2.2 2 0 0 2 2 2 0 X-domain of DnaJ-containing Ank_4 PF13637.6 GAM19860.1 - 0.26 11.9 3.8 14 6.4 0.1 4.8 5 1 0 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19861.1 - 0.016 15.7 1.7 47 5.0 0.0 6.0 7 0 0 7 7 7 0 Ankyrin repeat Guanylate_cyc PF00211.20 GAM19862.1 - 4.2e-110 365.5 5.4 5.2e-58 195.7 0.7 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain CH PF00307.31 GAM19863.1 - 1.3e-37 128.3 1.2 1.9e-17 63.4 0.1 3.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM19863.1 - 2.5e-05 24.0 0.6 0.00014 21.6 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain Herpes_IE2_3 PF03361.14 GAM19863.1 - 0.025 14.5 0.3 0.11 12.3 0.3 2.2 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Kelch_6 PF13964.6 GAM19864.1 - 1.1e-44 149.3 12.0 3.7e-09 36.5 0.1 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 GAM19864.1 - 5.5e-44 147.5 10.0 1.4e-09 37.4 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAM19864.1 - 2.7e-34 115.8 15.7 2.9e-07 30.2 0.3 6.8 6 1 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 GAM19864.1 - 1.4e-33 114.3 7.9 5.1e-05 23.1 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GAM19864.1 - 3.2e-28 97.5 16.9 4.5e-06 26.6 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM19864.1 - 1.2e-23 82.9 6.6 6.7e-08 32.6 0.0 7.2 7 0 0 7 7 7 4 Galactose oxidase, central domain F-box-like PF12937.7 GAM19864.1 - 6e-05 22.8 0.0 0.00019 21.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM19864.1 - 0.00011 22.0 0.1 0.0003 20.6 0.1 1.8 1 0 0 1 1 1 1 F-box domain DUF1668 PF07893.13 GAM19864.1 - 0.048 13.0 4.2 0.099 12.0 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1668) Spidroin_MaSp PF11260.8 GAM19864.1 - 0.72 10.2 2.2 1.6 9.0 2.2 1.5 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Ank_2 PF12796.7 GAM19865.1 - 0.0017 18.9 2.4 0.39 11.4 0.0 4.0 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM19865.1 - 0.045 14.3 2.6 48 5.0 0.0 5.9 7 0 0 7 7 7 0 Ankyrin repeat Peptidase_C1 PF00112.23 GAM19866.1 - 5.2e-62 209.8 10.9 6.3e-62 209.5 10.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAM19866.1 - 1.8 7.2 6.4 3.4 6.3 0.2 2.5 2 0 0 2 2 2 0 Peptidase C1-like family TFIID_NTD2 PF04494.15 GAM19869.1 - 0.24 11.6 2.9 2.3 8.5 0.1 2.5 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain DUF4351 PF14261.6 GAM19872.1 - 0.11 12.6 0.3 5 7.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) BRX PF08381.11 GAM19874.1 - 0.15 11.4 1.3 0.3 10.5 0.2 1.9 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 TPR_1 PF00515.28 GAM19875.1 - 1.6e-10 40.3 13.5 5.7e-05 22.8 0.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM19875.1 - 2.9e-09 36.3 11.4 0.0015 18.5 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat SET PF00856.28 GAM19875.1 - 5.9e-07 30.0 1.4 6.3e-07 29.9 0.9 1.7 1 1 0 1 1 1 1 SET domain TPR_8 PF13181.6 GAM19875.1 - 1.1e-05 25.2 11.0 0.042 14.1 0.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM19875.1 - 0.00074 19.1 0.7 0.00074 19.1 0.7 2.8 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 GAM19875.1 - 0.0082 16.9 0.3 2.4 9.2 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM19875.1 - 0.015 15.5 6.2 0.3 11.4 0.6 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM19875.1 - 0.1 12.7 3.6 1.5 9.0 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM19875.1 - 0.32 11.6 5.2 5.4 7.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat IGFL PF14653.6 GAM19875.1 - 1.2 9.2 9.4 0.44 10.6 4.7 2.7 3 0 0 3 3 3 0 Insulin growth factor-like family TPR_17 PF13431.6 GAM19875.1 - 2.2 8.9 5.5 41 4.9 0.5 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM19875.1 - 9 6.6 12.6 2.9 8.2 6.6 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 AMP-binding PF00501.28 GAM19876.1 - 4e-83 279.4 0.0 5.4e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM19876.1 - 2e-20 73.6 0.0 3.5e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPR_21 PF09976.9 GAM19876.1 - 0.037 13.7 0.8 0.054 13.2 0.1 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain RRM_1 PF00076.22 GAM19877.1 - 9.8e-17 60.6 0.0 1.8e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM19877.1 - 0.02 15.0 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif PMSR PF01625.21 GAM19878.1 - 1.4e-61 207.1 3.4 1.7e-61 206.9 3.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pkinase PF00069.25 GAM19879.1 - 1.3e-64 218.1 0.0 2.4e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19879.1 - 9.8e-42 143.0 0.0 2e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM19879.1 - 0.00015 21.2 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TSC22 PF01166.18 GAM19879.1 - 0.062 13.6 0.4 0.24 11.7 0.4 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family Seadorna_VP7 PF07387.11 GAM19879.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DivIC PF04977.15 GAM19879.1 - 0.24 11.2 0.7 6.6 6.6 0.0 2.7 2 0 0 2 2 2 0 Septum formation initiator TPR_19 PF14559.6 GAM19880.1 - 3.5e-07 30.6 2.6 0.018 15.5 0.0 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 GAM19880.1 - 2.6e-06 26.6 7.1 0.011 14.7 0.3 2.8 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 GAM19880.1 - 4.5e-05 23.3 4.7 0.013 15.6 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM19880.1 - 0.00027 21.0 0.2 0.0093 16.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM19880.1 - 0.0015 18.2 6.3 0.031 14.1 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM19880.1 - 0.0032 18.1 0.0 0.021 15.5 0.0 2.1 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM19880.1 - 0.0062 16.5 2.3 0.012 15.6 0.1 2.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM19880.1 - 0.0066 16.7 0.0 8.6 7.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM19880.1 - 0.014 16.0 3.0 81 4.2 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM19880.1 - 0.036 14.3 8.0 0.32 11.3 1.5 3.8 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 GAM19880.1 - 0.062 13.8 0.5 0.16 12.4 0.2 1.9 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation CP12 PF02672.15 GAM19880.1 - 0.11 13.3 1.1 3.6 8.4 0.4 2.5 2 0 0 2 2 2 0 CP12 domain TPR_8 PF13181.6 GAM19880.1 - 0.16 12.2 1.5 1.8 8.9 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM19880.1 - 0.32 11.3 6.4 0.46 10.8 1.2 3.2 4 1 0 4 4 3 0 Tetratricopeptide repeat DUF445 PF04286.12 GAM19880.1 - 3.3 7.4 6.3 13 5.4 6.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) NARP1 PF12569.8 GAM19881.1 - 8.1e-21 74.5 0.0 1.7e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Ribosomal_S4 PF00163.19 GAM19881.1 - 0.035 15.0 0.1 0.06 14.3 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain RHS_repeat PF05593.14 GAM19881.1 - 0.15 12.6 0.5 0.34 11.5 0.5 1.5 1 0 0 1 1 1 0 RHS Repeat COMM_domain PF07258.14 GAM19882.1 - 2.9e-13 49.7 3.4 3e-13 49.7 1.8 1.9 2 0 0 2 2 2 1 COMM domain COMMD1_N PF17221.3 GAM19882.1 - 3.9e-13 49.6 3.3 6.2e-13 48.9 0.5 2.1 2 0 0 2 2 2 1 COMMD1 N-terminal domain Ntox47 PF15540.6 GAM19882.1 - 0.038 14.3 0.1 0.13 12.6 0.1 1.7 1 1 1 2 2 2 0 Bacterial toxin 47 Antimicrobial10 PF08105.11 GAM19883.1 - 2.8 8.1 4.1 0.53 10.4 0.2 1.8 2 0 0 2 2 2 0 Metchnikowin family Atg8 PF02991.16 GAM19884.1 - 7.2e-32 109.7 0.1 8.7e-32 109.4 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 GAM19884.1 - 0.0014 19.0 0.1 0.0021 18.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Arm PF00514.23 GAM19885.1 - 5.1e-06 26.4 3.4 0.0019 18.2 0.0 6.2 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 GAM19885.1 - 0.00034 20.0 15.0 0.013 14.8 0.9 5.2 1 1 2 3 3 3 2 V-ATPase subunit H HEAT_2 PF13646.6 GAM19885.1 - 0.0016 18.8 0.5 0.14 12.6 0.0 4.1 4 2 2 6 6 6 1 HEAT repeats Uso1_p115_head PF04869.14 GAM19885.1 - 0.0053 15.9 3.0 0.01 15.0 0.4 2.5 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region DUF913 PF06025.12 GAM19885.1 - 0.017 14.1 0.0 0.017 14.1 0.0 2.9 3 1 0 3 3 3 0 Domain of Unknown Function (DUF913) HEAT PF02985.22 GAM19885.1 - 0.085 13.2 1.8 17 6.0 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat FOXP-CC PF16159.5 GAM19885.1 - 0.1 13.3 0.0 0.34 11.6 0.0 1.9 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF3361 PF11841.8 GAM19885.1 - 4 7.4 14.8 6.3 6.7 0.2 4.5 5 1 0 5 5 5 0 Domain of unknown function (DUF3361) Peptidase_M16 PF00675.20 GAM19886.1 - 3.7e-52 176.3 0.1 7.6e-52 175.3 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAM19886.1 - 2.1e-35 122.4 0.0 8.6e-35 120.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 GAM19886.1 - 0.0068 15.6 0.1 0.012 14.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Thioredoxin PF00085.20 GAM19887.1 - 4.1e-17 62.0 0.0 6.9e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAM19887.1 - 0.079 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Ribosomal_L36e PF01158.18 GAM19888.1 - 1.1e-31 108.9 3.9 1.2e-31 108.7 3.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DKCLD PF08068.12 GAM19888.1 - 0.059 13.4 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 DKCLD (NUC011) domain CKS PF01111.19 GAM19889.1 - 6.6e-31 106.4 2.9 6.6e-31 106.4 2.9 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit adh_short PF00106.25 GAM19890.1 - 2.4e-48 164.2 0.2 3e-48 163.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM19890.1 - 1.5e-47 162.1 0.2 1.9e-47 161.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM19890.1 - 1.4e-10 41.4 0.2 1.9e-10 40.9 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 GAM19890.1 - 0.00042 20.7 0.2 0.001 19.5 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Epimerase PF01370.21 GAM19890.1 - 0.00084 18.9 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 GAM19890.1 - 0.0014 19.1 0.1 0.0029 18.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 GAM19890.1 - 0.0028 17.0 0.0 0.073 12.4 0.0 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 GAM19890.1 - 0.016 15.5 0.2 0.047 13.9 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 GAM19890.1 - 0.044 13.7 0.1 0.085 12.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 GAM19890.1 - 0.057 13.5 1.5 0.11 12.6 0.6 1.8 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GDP_Man_Dehyd PF16363.5 GAM19890.1 - 0.075 12.4 0.0 1.4 8.3 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 GAM19890.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.19 GAM19890.1 - 0.12 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAM19890.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Acid_phosphat_B PF03767.14 GAM19890.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Ras PF00071.22 GAM19891.1 - 4.5e-38 130.4 0.0 5.4e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM19891.1 - 9.6e-27 93.6 0.0 1.5e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM19891.1 - 3e-16 59.4 0.0 4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM19891.1 - 7e-08 32.1 0.0 9e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM19891.1 - 1.7e-06 27.6 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM19891.1 - 0.00033 20.7 0.0 0.0005 20.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM19891.1 - 0.00088 18.9 0.0 0.0032 17.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 GAM19891.1 - 0.0009 19.0 0.1 0.081 12.7 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 GAM19891.1 - 0.0018 17.5 1.8 0.58 9.2 0.0 2.7 1 1 1 2 2 2 2 G-protein alpha subunit ATP_bind_1 PF03029.17 GAM19891.1 - 0.0031 17.3 0.2 0.017 14.9 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 GAM19891.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_15 PF13175.6 GAM19891.1 - 0.018 14.8 0.7 0.029 14.1 0.7 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 GAM19891.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 GAM19891.1 - 0.083 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 GAM19891.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 GAM19891.1 - 0.12 12.4 0.0 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 GAM19891.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Kelch_4 PF13418.6 GAM19892.1 - 4.1e-37 126.0 1.9 1.5e-07 31.3 0.0 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM19892.1 - 7.9e-37 124.4 13.8 2.3e-08 34.0 0.1 7.4 3 1 4 7 7 7 6 Kelch motif Kelch_1 PF01344.25 GAM19892.1 - 4.5e-36 122.2 23.5 4.9e-08 32.4 0.9 7.3 7 0 0 7 7 6 6 Kelch motif Kelch_3 PF13415.6 GAM19892.1 - 2.1e-14 53.4 16.7 2.4e-05 24.5 0.0 7.3 8 0 0 8 8 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM19892.1 - 1.7e-10 40.6 17.2 0.00017 21.5 0.0 6.8 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 GAM19892.1 - 8.6e-06 25.5 4.9 0.19 11.8 0.1 6.3 6 0 0 6 6 6 1 Kelch motif zf-B_box PF00643.24 GAM19892.1 - 0.00036 20.6 7.4 0.00036 20.6 7.4 3.6 3 0 0 3 3 3 1 B-box zinc finger zf-RING_UBOX PF13445.6 GAM19892.1 - 0.0027 17.7 1.8 0.0027 17.7 1.8 2.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAM19892.1 - 0.0094 16.1 2.2 0.0094 16.1 2.2 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAM19892.1 - 0.019 14.8 1.4 0.019 14.8 1.4 2.4 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM19892.1 - 0.91 9.4 16.8 0.017 15.0 6.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM19892.1 - 2.2 8.3 13.4 0.086 12.8 5.6 2.4 2 0 0 2 2 2 0 zinc-RING finger domain CEBP_ZZ PF16366.5 GAM19892.1 - 9.5 6.6 14.1 5.8 7.2 3.3 3.1 2 1 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Glutaredoxin2_C PF04399.13 GAM19893.1 - 0.046 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Kelch_6 PF13964.6 GAM19894.1 - 5.7e-12 45.5 2.9 0.0017 18.6 0.0 4.8 3 1 1 4 4 4 3 Kelch motif zf-B_box PF00643.24 GAM19894.1 - 5.9e-06 26.3 7.4 1.2e-05 25.4 7.4 1.5 1 0 0 1 1 1 1 B-box zinc finger Kelch_4 PF13418.6 GAM19894.1 - 1e-05 25.4 1.8 0.025 14.6 0.0 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM19894.1 - 5.4e-05 22.7 8.1 0.00019 21.0 0.0 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.6 GAM19894.1 - 0.014 15.4 3.3 25 5.0 0.1 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 GAM19894.1 - 0.017 15.1 4.9 23 5.2 0.1 3.7 2 1 1 3 3 3 0 Kelch motif Kelch_3 PF13415.6 GAM19894.1 - 0.024 14.9 2.7 3.4 8.1 0.0 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain YlbD_coat PF14071.6 GAM19894.1 - 2.2 8.6 6.5 4.1 7.7 1.3 2.8 3 0 0 3 3 3 0 Putative coat protein CYTL1 PF15153.6 GAM19895.1 - 0.078 12.9 0.3 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Cytokine-like protein 1 DUF1084 PF06454.11 GAM19896.1 - 4.7e-72 242.6 19.7 5.8e-72 242.3 19.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Sid-5 PF17204.3 GAM19896.1 - 0.84 9.9 6.5 1 9.6 0.1 3.3 3 0 0 3 3 3 0 Sid-5 family COPI_assoc PF08507.10 GAM19897.1 - 1.1e-14 54.6 3.1 1.5e-14 54.2 3.1 1.1 1 0 0 1 1 1 1 COPI associated protein DUF308 PF03729.13 GAM19897.1 - 0.00027 21.2 7.4 0.04 14.2 0.1 2.3 2 0 0 2 2 2 2 Short repeat of unknown function (DUF308) PEN-2 PF10251.9 GAM19897.1 - 0.019 15.3 2.3 0.039 14.4 0.2 2.2 2 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Phage_holin_2_1 PF04971.12 GAM19897.1 - 0.04 13.9 0.9 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage P21 holin S TMEM100 PF16311.5 GAM19897.1 - 0.04 13.5 3.2 0.1 12.2 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 100 LapA_dom PF06305.11 GAM19897.1 - 0.061 13.1 5.8 0.31 10.9 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF4345 PF14248.6 GAM19897.1 - 0.072 13.0 3.4 0.092 12.6 2.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) Phage_holin_2_4 PF16082.5 GAM19897.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF2157 PF09925.9 GAM19897.1 - 0.14 12.0 2.4 0.95 9.2 0.8 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3290 PF11694.8 GAM19897.1 - 0.24 11.4 2.6 4.4 7.3 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF202 PF02656.15 GAM19897.1 - 0.42 11.1 6.8 44 4.6 6.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF4131 PF13567.6 GAM19897.1 - 7.5 6.2 6.2 59 3.3 2.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Synaptobrevin PF00957.21 GAM19898.1 - 2.4e-25 88.1 3.5 2.7e-25 88.0 3.5 1.0 1 0 0 1 1 1 1 Synaptobrevin EVI2A PF05399.11 GAM19898.1 - 0.0023 17.6 0.3 0.0025 17.4 0.3 1.0 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) DUF2721 PF11026.8 GAM19898.1 - 0.0041 17.0 0.2 0.0051 16.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) CD34_antigen PF06365.12 GAM19898.1 - 0.005 16.5 0.8 0.0053 16.4 0.8 1.0 1 0 0 1 1 1 1 CD34/Podocalyxin family Spatacsin_C PF14649.6 GAM19898.1 - 0.025 13.7 0.0 0.028 13.5 0.0 1.0 1 0 0 1 1 1 0 Spatacsin C-terminus Orf78 PF06024.12 GAM19898.1 - 0.038 14.3 2.3 0.047 14.0 2.1 1.3 1 1 0 1 1 1 0 Orf78 (ac78) TolA_bind_tri PF16331.5 GAM19898.1 - 0.067 13.3 0.1 0.088 12.9 0.1 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation Pex24p PF06398.11 GAM19898.1 - 0.078 12.0 0.1 0.078 12.0 0.1 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin ETRAMP PF09716.10 GAM19898.1 - 0.16 12.0 2.0 0.19 11.8 2.0 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) ODV-E18 PF10717.9 GAM19898.1 - 0.18 11.7 1.5 0.26 11.2 1.5 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Sigma_reg_N PF13800.6 GAM19898.1 - 0.24 11.7 3.9 0.49 10.7 3.9 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal TMEM156 PF15106.6 GAM19898.1 - 1.3 8.4 7.1 1.5 8.2 7.1 1.3 1 1 0 1 1 1 0 TMEM156 protein family XhlA PF10779.9 GAM19898.1 - 1.3 9.3 8.8 1.4 9.1 7.2 2.0 1 1 0 1 1 1 0 Haemolysin XhlA Pkinase PF00069.25 GAM19899.1 - 4e-47 160.8 0.3 1.1e-46 159.4 0.3 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19899.1 - 1.5e-28 99.8 0.3 3.9e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase ANTH PF07651.16 GAM19899.1 - 7.7e-18 64.5 7.1 1.1e-17 64.0 0.7 2.6 3 0 0 3 3 3 1 ANTH domain Kinase-like PF14531.6 GAM19899.1 - 3.6e-07 29.8 0.0 0.00049 19.5 0.0 2.4 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 GAM19899.1 - 0.0016 18.4 0.0 1.2 9.0 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Nod1 PF17114.5 GAM19899.1 - 0.22 11.7 3.2 0.28 11.3 0.8 2.3 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 TFIIA PF03153.13 GAM19899.1 - 1.3 8.9 50.7 3.9 7.4 34.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Goodbye PF17109.5 GAM19899.1 - 6.9 7.1 7.4 10 6.6 0.8 3.5 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain CBM9_2 PF16011.5 GAM19900.1 - 2.4e-07 30.7 0.2 4.2e-07 29.9 0.2 1.3 1 1 0 1 1 1 1 Carbohydrate-binding family 9 CBM9_1 PF06452.11 GAM19900.1 - 7.6e-07 29.2 0.0 9.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like Pkinase PF00069.25 GAM19901.1 - 7.1e-79 264.9 0.4 1.8e-78 263.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM19901.1 - 1.9e-45 155.2 0.0 3e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 GAM19901.1 - 9.7e-16 57.3 0.1 2.1e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 GAM19901.1 - 2.8e-06 26.9 0.0 2.8e-05 23.6 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAM19901.1 - 0.0002 20.8 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM19901.1 - 0.00038 19.5 0.4 0.0012 17.9 0.4 1.8 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM19901.1 - 0.0032 17.4 0.0 0.084 12.8 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family YukC PF10140.9 GAM19901.1 - 0.013 14.4 0.2 0.013 14.4 0.2 2.4 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukC Abhydrolase_1 PF00561.20 GAM19903.1 - 6.3e-24 85.0 0.5 3.6e-23 82.5 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM19903.1 - 1e-15 58.9 0.0 1.3e-15 58.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM19903.1 - 4.5e-14 52.3 0.4 1.5e-13 50.6 0.4 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 GAM19903.1 - 0.00011 22.2 1.7 0.0024 17.8 0.1 2.5 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 GAM19903.1 - 0.00089 18.9 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.20 GAM19903.1 - 0.0011 18.7 0.9 0.0021 17.7 0.3 2.0 1 1 0 2 2 2 1 Putative esterase FSH1 PF03959.13 GAM19903.1 - 0.003 17.3 0.2 0.32 10.6 0.0 2.5 1 1 1 2 2 2 1 Serine hydrolase (FSH1) DUF2048 PF09752.9 GAM19903.1 - 0.0082 15.3 0.2 0.038 13.1 0.2 1.9 1 1 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_2 PF02230.16 GAM19903.1 - 0.011 15.6 0.2 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 GAM19903.1 - 0.035 14.2 0.1 0.24 11.5 0.0 2.1 1 1 1 2 2 2 0 Thioesterase domain Glyco_hydro_18 PF00704.28 GAM19904.1 - 1.5e-26 93.9 0.3 9.2e-26 91.3 0.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Rap_GAP PF02145.15 GAM19905.1 - 2.6e-42 144.5 3.5 1.4e-41 142.1 0.6 2.9 3 0 0 3 3 3 1 Rap/ran-GAP DAG_kinase_N PF14513.6 GAM19905.1 - 0.016 15.4 1.5 0.016 15.4 1.5 2.6 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus SRP14 PF02290.15 GAM19905.1 - 0.046 14.1 1.1 3.5 8.1 0.2 2.8 2 0 0 2 2 2 0 Signal recognition particle 14kD protein TFIIA PF03153.13 GAM19905.1 - 0.78 9.7 23.7 0.25 11.3 12.0 2.8 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 GAM19905.1 - 4.5 6.8 13.7 0.2 11.3 4.4 2.4 2 0 0 2 2 2 0 Spt20 family EXS PF03124.14 GAM19906.1 - 9.9e-91 304.5 25.1 1.3e-90 304.1 25.1 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 GAM19906.1 - 1.1e-35 124.3 28.5 6.6e-35 121.8 22.9 2.8 2 1 0 2 2 2 1 SPX domain cwf18 PF08315.12 GAM19906.1 - 0.08 13.6 1.3 0.18 12.5 1.3 1.6 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor zf-CRD PF17979.1 GAM19906.1 - 0.086 12.9 0.4 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions CAP_N PF01213.19 GAM19906.1 - 2.6 7.4 9.2 14 5.0 0.0 2.6 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal RRM_3 PF08777.11 GAM19907.1 - 4.9e-23 81.1 1.7 5.1e-22 77.8 0.1 2.7 2 1 0 2 2 2 1 RNA binding motif La PF05383.17 GAM19907.1 - 9.3e-20 70.4 0.3 1.6e-19 69.7 0.3 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 GAM19907.1 - 4.2e-08 32.9 0.1 0.0033 17.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VitD-bind_III PF09164.10 GAM19907.1 - 0.017 15.1 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III UPA_2 PF17809.1 GAM19907.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 UPA domain LIM PF00412.22 GAM19908.1 - 2.6e-58 194.1 101.3 8.4e-15 54.7 2.2 10.6 8 2 2 10 10 10 9 LIM domain CH PF00307.31 GAM19908.1 - 6.8e-19 68.1 0.1 1.9e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 GAM19908.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 CDC24 Calponin DUF1462 PF07315.11 GAM19908.1 - 0.18 12.1 0.6 6.7 7.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1462) Inositol_P PF00459.25 GAM19909.1 - 5.7e-44 150.7 0.0 7.3e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF2678 PF10856.8 GAM19909.1 - 0.12 12.3 0.0 6.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) LRR_6 PF13516.6 GAM19910.1 - 3.7e-33 110.7 47.2 3.1e-05 23.7 0.0 13.1 13 0 0 13 13 13 11 Leucine Rich repeat LRR_1 PF00560.33 GAM19910.1 - 1.3e-09 37.2 12.1 2.1 9.2 0.1 10.2 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_4 PF12799.7 GAM19910.1 - 3.2e-06 27.4 36.0 0.14 12.6 0.0 9.1 7 2 4 11 11 11 7 Leucine Rich repeats (2 copies) F-box-like PF12937.7 GAM19910.1 - 7.6e-06 25.7 0.0 3.8e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 F-box-like Sporozoite_P67 PF05642.11 GAM19910.1 - 0.021 13.0 7.4 0.03 12.4 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LRR_8 PF13855.6 GAM19910.1 - 0.51 10.1 40.3 1.4 8.7 0.0 10.2 5 3 4 9 9 9 0 Leucine rich repeat CoA_transf_3 PF02515.17 GAM19911.1 - 2.4e-116 388.9 0.0 5.6e-116 387.7 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III SAM_4 PF18017.1 GAM19911.1 - 0.034 14.1 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Aminotran_1_2 PF00155.21 GAM19912.1 - 2.9e-65 220.8 0.0 3.3e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAM19912.1 - 6.6e-07 28.6 0.0 1.5e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAM19912.1 - 3e-06 26.0 0.0 4.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 GAM19912.1 - 3.8e-06 26.4 0.0 6.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAM19912.1 - 0.00014 21.3 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_20 PF00728.22 GAM19912.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain UPF0052 PF01933.18 GAM19912.1 - 0.12 11.6 0.0 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 Aminotran_MocR PF12897.7 GAM19912.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Nucleoporin_C PF03177.14 GAM19913.1 - 2.9e-12 46.1 25.2 4.1e-11 42.3 22.9 3.0 2 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Epimerase PF01370.21 GAM19914.1 - 1.2e-13 51.1 0.0 1.7e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM19914.1 - 8e-10 38.3 0.0 1.1e-09 37.8 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAM19914.1 - 0.0003 20.0 0.1 0.0009 18.5 0.0 1.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAM19914.1 - 0.0014 18.1 0.0 0.0045 16.4 0.0 1.8 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase SH3_2 PF07653.17 GAM19915.1 - 4.9e-13 48.6 0.0 7.7e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAM19915.1 - 5.3e-09 35.8 0.1 5.3e-09 35.8 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 GAM19915.1 - 2.3e-05 23.9 0.1 2.3e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 SH3 domain PfkB PF00294.24 GAM19916.1 - 2.3e-62 211.0 0.1 2.7e-62 210.8 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DEC-1_C PF04626.13 GAM19916.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Dec-1 protein, C terminal region ELFV_dehydrog PF00208.21 GAM19917.1 - 7.8e-56 189.5 0.1 5.2e-53 180.3 0.0 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 GAM19917.1 - 8.7e-56 187.4 0.0 1.5e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 GAM19917.1 - 0.002 17.5 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 GAM19917.1 - 0.0072 16.7 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Bac_GDH PF05088.12 GAM19917.1 - 0.0076 13.8 0.0 0.22 8.9 0.0 2.0 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase AdoHcyase_NAD PF00670.21 GAM19917.1 - 0.0079 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RRM_1 PF00076.22 GAM19918.1 - 6.5e-39 131.6 0.1 1.1e-17 63.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM19918.1 - 1.1e-06 28.5 0.1 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAM19918.1 - 0.0081 16.2 4.1 0.83 9.7 0.0 3.5 4 0 0 4 4 4 2 RNA binding motif CDK5_activator PF03261.15 GAM19918.1 - 8 5.9 22.1 12 5.3 22.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Citrate_synt PF00285.21 GAM19919.1 - 2.1e-91 306.7 0.0 1.3e-50 172.5 0.0 2.1 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ras PF00071.22 GAM19920.1 - 1.3e-48 164.7 0.6 2.7e-35 121.4 0.1 2.5 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAM19920.1 - 3.8e-19 69.1 0.1 1.5e-10 41.4 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM19920.1 - 3.2e-06 26.7 0.4 0.0038 16.7 0.1 3.4 3 1 1 4 4 4 2 ADP-ribosylation factor family VWA_2 PF13519.6 GAM19920.1 - 0.0001 22.9 0.0 0.021 15.5 0.0 3.2 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-Sec23_Sec24 PF04810.15 GAM19920.1 - 0.00015 21.8 5.6 0.00031 20.7 5.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger MMR_HSR1 PF01926.23 GAM19920.1 - 0.0019 18.3 0.0 2.9 8.0 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF1040 PF06288.13 GAM19920.1 - 0.0019 18.5 0.1 0.0069 16.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1040) Sec23_trunk PF04811.15 GAM19920.1 - 0.0046 16.6 0.0 0.078 12.5 0.0 2.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain RsgA_GTPase PF03193.16 GAM19920.1 - 0.0087 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase DUF2076 PF09849.9 GAM19920.1 - 0.018 15.1 0.1 0.036 14.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TniB PF05621.11 GAM19920.1 - 0.043 13.2 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Sec23_BS PF08033.12 GAM19920.1 - 0.063 14.0 0.0 0.26 12.0 0.0 2.0 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain FNIP PF05725.12 GAM19921.1 - 7e-29 99.7 0.0 8.4e-10 38.7 0.1 3.1 1 1 2 3 3 3 3 FNIP Repeat LRR_5 PF13306.6 GAM19921.1 - 1.3e-05 25.2 0.0 4.1e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) BING4CT PF08149.11 GAM19921.1 - 0.04 13.7 0.1 27 4.6 0.0 3.5 1 1 2 3 3 3 0 BING4CT (NUC141) domain DUF2475 PF10629.9 GAM19921.1 - 1 9.6 4.2 40 4.5 0.1 4.5 4 2 2 6 6 6 0 Protein of unknown function (DUF2475) Myb_DNA-binding PF00249.31 GAM19922.1 - 1.6e-51 172.2 34.6 1.8e-15 56.8 0.5 5.7 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM19922.1 - 2.7e-49 165.3 25.3 8.9e-15 54.7 0.1 6.2 1 1 4 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 GAM19922.1 - 3.3e-08 33.5 8.5 0.53 10.3 0.1 5.5 2 1 3 5 5 5 4 SLIDE MADF_DNA_bdg PF10545.9 GAM19922.1 - 0.022 15.1 10.5 5.1 7.5 0.1 5.0 3 2 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.11 GAM19922.1 - 0.031 14.4 3.6 14 6.0 0.1 4.0 3 1 0 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 GAM19922.1 - 0.055 13.8 20.6 0.35 11.3 1.5 5.9 4 2 1 5 5 5 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAM19922.1 - 0.39 11.0 8.4 12 6.2 0.1 4.7 3 2 3 6 6 6 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 GAM19922.1 - 0.42 10.7 15.4 6 7.0 0.9 5.0 3 1 1 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4805 PF16063.5 GAM19922.1 - 8.8 5.6 23.0 0.83 8.9 4.4 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4805) FNIP PF05725.12 GAM19923.1 - 5.5e-96 314.5 49.3 3e-12 46.5 0.2 9.2 5 2 4 10 10 10 10 FNIP Repeat SpoU_methylase PF00588.19 GAM19924.1 - 2.3e-25 89.4 0.0 5e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family HEAT PF02985.22 GAM19924.1 - 0.13 12.6 0.0 51 4.5 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat Fascin PF06268.13 GAM19925.1 - 2.1e-07 31.2 0.0 2.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Fascin domain FGF PF00167.18 GAM19925.1 - 8.3e-05 22.7 0.0 9.1e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Fibroblast growth factor FRG1 PF06229.12 GAM19925.1 - 0.0078 15.9 0.0 0.5 10.1 0.0 2.0 1 1 0 1 1 1 1 FRG1-like domain E1_dh PF00676.20 GAM19926.1 - 0.032 13.2 0.2 0.068 12.1 0.2 1.5 1 0 0 1 1 1 0 Dehydrogenase E1 component Ribosomal_60s PF00428.19 GAM19926.1 - 0.58 10.8 8.1 1.5 9.5 1.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_hydro_9 PF00759.19 GAM19927.1 - 3.3e-125 418.8 7.8 3.7e-125 418.6 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 RLL PF10036.9 GAM19928.1 - 2.4e-54 184.9 3.1 3e-54 184.6 3.1 1.1 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein DUF3473 PF11959.8 GAM19928.1 - 0.0097 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3473) DUF3439 PF11921.8 GAM19928.1 - 0.57 10.2 13.1 1.7 8.6 11.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 GAM19928.1 - 0.57 8.3 12.9 0.86 7.7 12.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.11 GAM19928.1 - 2.5 6.1 7.7 3.7 5.5 7.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PI3_PI4_kinase PF00454.27 GAM19929.1 - 8.6e-51 173.2 0.0 2.1e-50 171.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 GAM19929.1 - 1.8e-28 99.4 5.9 1.8e-28 99.4 5.9 3.8 2 1 0 2 2 2 1 Serine/threonine-protein kinase smg-1 FATC PF02260.20 GAM19929.1 - 1.8e-10 40.4 0.0 4.9e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 FATC domain DNA_pol3_delt_C PF14840.6 GAM19929.1 - 0.63 10.4 5.6 0.79 10.1 3.3 2.3 2 0 0 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term ArfGap PF01412.18 GAM19930.1 - 3.7e-37 127.0 0.1 3.7e-37 127.0 0.1 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.29 GAM19930.1 - 1.6e-20 73.5 1.5 5.3e-14 52.6 0.1 3.1 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 GAM19930.1 - 1.1e-09 38.6 2.1 5e-05 23.7 0.4 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 GAM19930.1 - 0.0012 19.2 0.2 0.4 11.1 0.0 2.8 2 1 0 2 2 2 2 Pleckstrin homology domain Sugar_tr PF00083.24 GAM19931.1 - 6.4e-41 140.7 25.3 4.4e-39 134.6 25.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM19931.1 - 1.5e-38 132.7 45.3 1.2e-31 110.0 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.12 GAM19931.1 - 0.092 12.2 0.1 0.29 10.6 0.0 1.8 1 1 0 1 1 1 0 Emopamil binding protein RNA_pol_Rpc4 PF05132.14 GAM19932.1 - 0.22 11.9 2.7 0.28 11.6 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 ELO PF01151.18 GAM19933.1 - 3.6e-66 223.2 20.6 4.4e-66 222.9 20.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ank_2 PF12796.7 GAM19934.1 - 3.2e-24 85.3 5.2 6.6e-11 42.7 0.2 4.0 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19934.1 - 4.9e-18 65.3 7.2 7.3e-05 23.2 0.1 7.3 5 1 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM19934.1 - 8.9e-16 57.8 12.8 0.00086 19.6 0.1 8.1 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19934.1 - 2.8e-13 48.7 5.2 3.4 8.5 0.0 8.4 8 0 0 8 8 8 2 Ankyrin repeat DUF1843 PF08898.10 GAM19934.1 - 0.087 13.3 0.0 5.1 7.7 0.0 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF1843) Ank PF00023.30 GAM19934.1 - 0.27 11.8 7.6 2.7e+02 2.3 0.1 5.9 2 2 0 2 2 2 0 Ankyrin repeat Ras PF00071.22 GAM19935.1 - 6.5e-44 149.4 0.2 7.3e-32 110.2 0.1 2.9 2 0 0 2 2 2 2 Ras family bMG10 PF17973.1 GAM19935.1 - 3.3e-25 88.8 0.2 1.3e-24 86.8 0.2 2.2 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M_BRD PF07703.14 GAM19935.1 - 2.2e-14 54.0 0.1 3.2e-13 50.2 0.0 3.3 3 0 0 3 3 3 1 Alpha-2-macroglobulin bait region domain Roc PF08477.13 GAM19935.1 - 8.6e-13 48.6 0.0 7.4e-07 29.4 0.0 3.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase A2M PF00207.22 GAM19935.1 - 6.4e-10 38.8 0.4 6.3e-09 35.6 0.1 3.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin family Big_5 PF13205.6 GAM19935.1 - 9.8e-08 32.7 2.9 3.2e-06 27.8 0.3 14.0 12 2 1 13 13 13 5 Bacterial Ig-like domain MG2 PF01835.19 GAM19935.1 - 2.8e-06 27.7 0.3 0.00086 19.7 0.0 4.5 4 0 0 4 4 4 1 MG2 domain Arf PF00025.21 GAM19935.1 - 0.0042 16.6 0.0 0.17 11.3 0.0 2.7 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF748 PF05359.11 GAM19935.1 - 0.098 12.8 0.0 2 8.5 0.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF748) Ank_2 PF12796.7 GAM19936.1 - 7.6e-06 26.4 0.3 0.047 14.3 0.0 4.0 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM19936.1 - 0.00036 20.8 0.8 14 6.6 0.0 6.1 7 0 0 7 7 5 0 Ankyrin repeat Ank_4 PF13637.6 GAM19936.1 - 0.015 15.9 0.1 1.3e+02 3.3 0.0 5.3 5 0 0 5 5 5 0 Ankyrin repeats (many copies) PPP4R2 PF09184.11 GAM19936.1 - 0.018 14.6 15.7 0.027 14.1 15.7 1.3 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 GAM19936.1 - 0.11 10.6 27.7 0.19 9.8 27.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF4746 PF15928.5 GAM19936.1 - 0.26 10.7 6.3 0.43 10.0 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 GAM19936.1 - 0.36 11.1 25.0 0.53 10.5 24.3 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2722 PF10846.8 GAM19936.1 - 0.45 9.4 6.0 0.61 9.0 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 GAM19936.1 - 1.1 9.2 14.8 1.5 8.7 14.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRN3 PF05327.11 GAM19936.1 - 1.2 7.6 11.4 2.2 6.7 11.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 GAM19936.1 - 1.4 8.2 24.0 2.2 7.6 24.0 1.2 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 GAM19936.1 - 1.7 8.5 8.8 3.9 7.4 8.8 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SDA1 PF05285.12 GAM19936.1 - 3.2 7.1 22.8 5 6.4 22.8 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 GAM19936.1 - 4.6 7.1 15.3 6.5 6.6 14.5 1.7 2 0 0 2 2 1 0 Sigma-70, non-essential region BUD22 PF09073.10 GAM19936.1 - 6.2 6.0 16.8 9.3 5.5 16.8 1.2 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 GAM19936.1 - 6.5 6.5 10.5 13 5.5 10.5 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Mis12 PF05859.12 GAM19941.1 - 4.3e-18 65.7 1.7 1e-17 64.4 1.7 1.6 1 0 0 1 1 1 1 Mis12 protein CCDC144C PF14915.6 GAM19941.1 - 0.002 17.3 11.6 0.11 11.6 2.5 2.2 2 0 0 2 2 2 2 CCDC144C protein coiled-coil region CLZ PF16526.5 GAM19941.1 - 0.016 15.6 5.0 0.05 14.0 3.5 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin_2 PF14523.6 GAM19941.1 - 0.043 14.2 0.2 0.043 14.2 0.2 2.6 2 1 0 2 2 2 0 Syntaxin-like protein DUF1319 PF07028.11 GAM19941.1 - 0.062 13.5 2.6 0.18 12.0 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) TMPIT PF07851.13 GAM19941.1 - 0.28 10.4 2.8 0.42 9.8 2.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 GAM19941.1 - 2.1 8.2 9.2 6.5 6.6 4.8 3.1 2 1 0 2 2 2 0 Septum formation initiator FlxA PF14282.6 GAM19941.1 - 4.6 7.3 11.0 0.21 11.6 4.3 2.0 2 0 0 2 2 2 0 FlxA-like protein Imm58 PF15581.6 GAM19943.1 - 0.24 11.5 0.7 9 6.4 0.1 2.2 1 1 1 2 2 2 0 Immunity protein 58 LisH PF08513.11 GAM19947.1 - 2.4e-05 24.1 0.0 5.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 LisH NOC3p PF07540.11 GAM19948.1 - 4.9e-26 91.0 2.7 4.9e-26 91.0 2.7 3.2 2 1 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 GAM19948.1 - 5.3e-19 68.9 0.0 5.3e-19 68.9 0.0 3.2 2 1 0 3 3 3 1 CBF/Mak21 family MCM PF00493.23 GAM19949.1 - 6.1e-101 336.2 0.0 1.3e-100 335.1 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAM19949.1 - 1.1e-34 119.0 0.2 2.4e-34 117.9 0.2 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAM19949.1 - 1.2e-27 96.1 1.3 2.6e-27 95.1 1.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAM19949.1 - 1.7e-17 63.9 3.0 3.9e-17 62.8 2.3 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAM19949.1 - 3e-06 26.8 0.0 0.0014 18.1 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAM19949.1 - 5.8e-05 23.1 0.0 0.00015 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAM19949.1 - 0.0011 18.8 0.0 0.0036 17.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAM19949.1 - 0.019 14.7 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain TBPIP PF07106.13 GAM19949.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain PIH1 PF08190.12 GAM19950.1 - 3e-10 39.8 0.1 3e-10 39.8 0.1 2.0 3 0 0 3 3 3 1 PIH1 N-terminal domain PIH1_CS PF18201.1 GAM19950.1 - 6.4e-08 32.9 0.2 1.9e-07 31.4 0.2 1.8 1 0 0 1 1 1 1 PIH1 CS-like domain PcfK PF14058.6 GAM19950.1 - 0.01 16.1 0.5 3.3 8.0 0.1 2.3 2 0 0 2 2 2 0 PcfK-like protein Mucin PF01456.17 GAM19950.1 - 0.093 12.7 22.5 0.18 11.8 22.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Orthopox_A5L PF06193.11 GAM19950.1 - 0.25 10.8 16.4 1.1 8.6 14.2 2.3 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like SDP_N PF12278.8 GAM19950.1 - 0.77 9.9 7.1 3.2 7.9 1.3 2.4 2 0 0 2 2 2 0 Sex determination protein N terminal MGC-24 PF05283.11 GAM19950.1 - 6.6 7.2 13.2 16 5.9 13.2 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin LNS2 PF08235.13 GAM19951.1 - 2.4e-97 324.9 0.0 3.9e-97 324.2 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 GAM19951.1 - 5.6e-37 125.8 0.0 1.4e-36 124.5 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 GAM19951.1 - 2.3e-20 72.6 0.0 2.3e-20 72.6 0.0 2.6 2 0 0 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain UQ_con PF00179.26 GAM19952.1 - 4.9e-38 129.9 0.0 5.6e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM19952.1 - 0.049 13.3 0.0 0.074 12.8 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B RCR PF12273.8 GAM19953.1 - 5.3e-05 23.9 12.8 6.8e-05 23.5 12.8 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red ODV-E18 PF10717.9 GAM19953.1 - 0.0068 16.2 0.5 0.0094 15.8 0.5 1.2 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 GAM19953.1 - 0.027 15.3 2.6 0.027 15.3 2.6 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 GAM19953.1 - 0.03 14.6 10.0 0.044 14.0 10.0 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM132D_C PF15706.5 GAM19953.1 - 0.21 11.4 0.2 0.27 11.0 0.2 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DAP10 PF07213.11 GAM19953.1 - 0.26 11.3 1.9 0.42 10.6 1.9 1.4 1 0 0 1 1 1 0 DAP10 membrane protein TMEM154 PF15102.6 GAM19953.1 - 0.53 10.2 2.4 0.71 9.8 2.4 1.2 1 0 0 1 1 1 0 TMEM154 protein family RIFIN PF02009.16 GAM19953.1 - 0.66 9.8 4.7 0.76 9.6 4.7 1.1 1 0 0 1 1 1 0 Rifin ECSCR PF15820.5 GAM19953.1 - 3.9 7.4 4.9 5.2 6.9 4.9 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator AAA_5 PF07728.14 GAM19955.1 - 0.0003 20.8 0.0 0.035 14.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM19955.1 - 0.00061 20.1 0.1 1.5 9.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain TFIID-31kDa PF02291.15 GAM19955.1 - 0.056 13.5 0.2 0.87 9.7 0.0 2.9 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit ABC_tran PF00005.27 GAM19955.1 - 0.1 13.1 0.0 1.8 9.1 0.0 2.9 2 0 0 2 2 2 0 ABC transporter Trypan_PARP PF05887.11 GAM19955.1 - 0.91 9.5 3.7 1.9 8.5 3.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) IBR PF01485.21 GAM19955.1 - 5.2 7.4 15.8 1.7 8.9 4.7 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain AIG1 PF04548.16 GAM19956.1 - 3e-07 30.0 0.1 1e-06 28.2 0.1 1.9 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GAM19956.1 - 3.2e-05 24.0 0.8 3.2e-05 24.0 0.8 2.6 2 2 0 2 2 2 1 50S ribosome-binding GTPase V-SNARE PF05008.15 GAM19956.1 - 0.036 14.4 3.1 0.07 13.5 0.1 2.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus ANF_receptor PF01094.28 GAM19956.1 - 0.05 12.7 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region Dynamin_N PF00350.23 GAM19956.1 - 0.093 12.8 0.2 0.093 12.8 0.2 3.3 3 1 0 4 4 4 0 Dynamin family DUF5082 PF16888.5 GAM19956.1 - 0.3 11.4 4.5 0.43 10.8 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) Laminin_II PF06009.12 GAM19956.1 - 0.44 10.6 5.7 0.19 11.7 1.3 2.5 2 1 0 2 2 2 0 Laminin Domain II DHR10 PF18595.1 GAM19956.1 - 1.5 8.9 5.3 2.6 8.1 1.1 2.6 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Ank_2 PF12796.7 GAM19958.1 - 5.3e-31 107.0 20.4 3.1e-09 37.3 0.1 6.5 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM19958.1 - 2.7e-22 78.8 19.2 0.00034 21.1 0.0 10.4 8 3 1 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM19958.1 - 4.4e-16 58.7 16.9 0.0046 17.2 0.0 11.1 5 2 6 12 12 12 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM19958.1 - 1e-15 56.2 18.3 3.1 8.6 0.0 13.9 14 1 1 15 15 15 3 Ankyrin repeat DUF5049 PF16468.5 GAM19958.1 - 3.1e-08 33.4 0.5 5.4 7.0 0.1 6.4 5 1 1 6 6 6 3 Domain of unknown function (DUF5049) DUF3447 PF11929.8 GAM19958.1 - 6.4e-07 29.2 9.4 0.0045 16.9 0.0 5.8 4 1 2 6 6 6 2 Domain of unknown function (DUF3447) Ank PF00023.30 GAM19958.1 - 0.3 11.6 15.8 1.4e+02 3.1 0.3 8.6 7 3 1 8 8 8 0 Ankyrin repeat RabGAP-TBC PF00566.18 GAM19959.1 - 5.1e-55 186.4 0.3 9.5e-55 185.6 0.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SWIM PF04434.17 GAM19960.1 - 6.7e-06 25.7 0.3 1.3e-05 24.7 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger AAA_33 PF13671.6 GAM19960.1 - 0.02 15.1 0.0 0.086 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain TMEM154 PF15102.6 GAM19960.1 - 3 7.8 7.2 12 5.8 7.2 2.0 1 0 0 1 1 1 0 TMEM154 protein family Pkinase PF00069.25 GAM19961.1 - 1e-61 208.6 0.1 2.2e-41 142.0 0.5 2.1 2 0 0 2 2 2 2 Protein kinase domain PH_3 PF14593.6 GAM19961.1 - 3.9e-38 129.7 0.7 7.3e-38 128.8 0.7 1.4 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 GAM19961.1 - 3.4e-35 121.6 0.0 5e-26 91.5 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAM19961.1 - 2.8e-07 30.1 0.1 0.0037 16.6 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 GAM19961.1 - 2.9e-06 26.5 0.2 2.9e-06 26.5 0.2 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 GAM19961.1 - 0.043 13.7 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 GAM19961.1 - 0.067 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 GAM19961.1 - 0.1 13.1 0.9 0.26 11.8 0.2 2.0 2 0 0 2 2 2 0 PH domain RIO1 PF01163.22 GAM19961.1 - 0.1 12.1 0.3 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 GAM19961.1 - 0.29 9.9 2.1 0.62 8.8 2.1 1.7 1 1 0 1 1 1 0 Fungal protein kinase Ribosomal_L29e PF01779.17 GAM19962.1 - 1.3e-18 67.0 10.9 1.3e-18 67.0 10.9 2.1 2 0 0 2 2 2 1 Ribosomal L29e protein family Integrase_Zn PF02022.19 GAM19962.1 - 0.6 10.1 5.4 26 4.9 0.0 2.4 2 0 0 2 2 2 0 Integrase Zinc binding domain zf-C2H2 PF00096.26 GAM19963.1 - 2.1e-25 87.7 70.5 1.1e-05 25.6 7.0 9.4 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAM19963.1 - 3.1e-23 81.1 67.3 5.4e-08 32.9 2.2 10.2 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAM19963.1 - 3.5e-18 64.7 67.5 0.0024 18.6 5.2 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf_Hakai PF18408.1 GAM19963.1 - 0.00054 19.6 0.1 0.00054 19.6 0.1 6.3 7 0 0 7 7 7 2 C2H2 Hakai zinc finger domain zf-C2H2_11 PF16622.5 GAM19963.1 - 0.015 15.1 0.0 0.015 15.1 0.0 7.1 8 0 0 8 8 8 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 GAM19963.1 - 0.056 13.7 31.5 0.96 9.8 6.5 4.2 1 1 2 4 4 4 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 GAM19963.1 - 0.059 13.1 0.5 0.059 13.1 0.5 9.8 10 0 0 10 10 10 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 GAM19963.1 - 0.17 12.2 41.1 0.35 11.2 2.1 8.6 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 GAM19963.1 - 0.8 9.8 12.5 2 8.5 0.9 3.8 2 1 1 3 3 3 0 CpXC protein CENP-B_dimeris PF09026.10 GAM19963.1 - 2.1 8.8 10.0 0.86 10.0 1.7 2.8 3 0 0 3 3 3 0 Centromere protein B dimerisation domain zf-met PF12874.7 GAM19963.1 - 4.3 7.9 0.0 1.5 9.3 3.3 7.2 8 1 0 8 8 8 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 GAM19963.1 - 7.3 6.8 15.1 2.6 8.2 2.5 3.9 3 1 0 3 3 3 0 Zinc ribbon domain PBP1_TM PF14812.6 GAM19963.1 - 7.9 6.9 8.4 4.8 7.6 0.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ILEI PF15711.5 GAM19964.1 - 6.6e-45 151.5 3.7 3e-12 46.9 0.1 4.7 5 1 0 5 5 5 4 Interleukin-like EMT inducer Peptidase_C14 PF00656.22 GAM19965.1 - 2e-05 24.7 0.0 2.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Caspase domain ILEI PF15711.5 GAM19967.1 - 6.7e-42 141.9 8.8 5.1e-11 42.9 0.1 5.3 5 0 0 5 5 5 5 Interleukin-like EMT inducer DDE_3 PF13358.6 GAM19968.1 - 3.5e-20 72.3 0.0 4.8e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease ILEI PF15711.5 GAM19969.1 - 5.8e-62 206.2 4.6 6e-15 55.5 0.0 5.7 5 0 0 5 5 5 5 Interleukin-like EMT inducer Peptidase_C14 PF00656.22 GAM19969.1 - 7e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Caspase domain DUF5600 PF18150.1 GAM19970.1 - 2.6e-40 137.3 0.7 5.4e-40 136.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 GAM19970.1 - 5e-22 77.8 0.0 1.7e-21 76.1 0.0 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 GAM19970.1 - 1.8e-14 53.3 0.0 3.6e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein EF-hand_1 PF00036.32 GAM19970.1 - 1.2e-06 27.7 0.3 3.7e-06 26.1 0.1 2.1 2 0 0 2 2 1 1 EF hand Dynamin_N PF00350.23 GAM19970.1 - 1.1e-05 25.6 0.0 6.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAM19970.1 - 0.00015 21.9 0.0 0.0004 20.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_7 PF13499.6 GAM19970.1 - 0.0028 18.1 0.1 0.024 15.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM19970.1 - 0.0034 17.2 0.0 0.016 15.1 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 GAM19970.1 - 0.011 15.1 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 GAM19970.1 - 0.013 15.4 0.5 0.059 13.2 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain pair GTP_EFTU PF00009.27 GAM19970.1 - 0.057 12.9 0.0 0.26 10.8 0.0 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Isochorismatase PF00857.20 GAM19970.1 - 0.22 11.7 0.0 0.37 11.0 0.0 1.3 1 0 0 1 1 1 0 Isochorismatase family Ribosom_S12_S23 PF00164.25 GAM19971.1 - 6.1e-48 161.2 0.7 7.8e-48 160.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Peptidase_M28 PF04389.17 GAM19972.1 - 1.4e-17 64.0 0.0 1.2e-16 61.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 GAM19972.1 - 0.083 12.3 0.0 1.7 8.1 0.0 2.6 2 1 0 2 2 2 0 Nicastrin VWA_2 PF13519.6 GAM19973.1 - 1.6e-05 25.5 0.1 4e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAM19973.1 - 0.017 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Autophagy_N PF03986.13 GAM19974.1 - 9.4e-43 145.5 0.9 1.2e-42 145.1 0.9 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Yippee-Mis18 PF03226.14 GAM19975.1 - 0.0001 22.5 3.7 0.00016 21.9 3.7 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 GAM19975.1 - 0.001 19.1 1.2 0.0019 18.3 1.2 1.5 1 0 0 1 1 1 1 SelR domain DUF647 PF04884.14 GAM19976.1 - 1.3e-95 319.6 0.4 2.1e-95 318.9 0.4 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis PA14 PF07691.12 GAM19976.1 - 5.3e-13 49.0 0.1 9.7e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 GAM19976.1 - 5e-05 23.1 7.9 5e-05 23.1 7.9 14.3 16 2 1 17 17 17 6 Dictyostelium (slime mold) repeat OppC_N PF12911.7 GAM19976.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PA14 PF07691.12 GAM19977.1 - 3.2e-15 56.2 0.2 5.6e-15 55.4 0.2 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 GAM19977.1 - 9.8e-09 35.0 28.3 4.4e-06 26.5 7.3 14.9 14 1 1 15 15 15 7 Dictyostelium (slime mold) repeat Dicty_CTDC PF00526.18 GAM19978.1 - 2.5e-08 33.6 35.7 3.8e-06 26.7 6.5 13.7 13 2 0 13 13 13 9 Dictyostelium (slime mold) repeat PA14 PF07691.12 GAM19978.1 - 1.4e-06 28.2 0.3 5.4e-06 26.3 0.3 1.9 1 1 0 1 1 1 1 PA14 domain OppC_N PF12911.7 GAM19978.1 - 0.16 12.0 0.8 1 9.4 0.1 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Rad21_Rec8_N PF04825.13 GAM19980.1 - 2.7e-35 120.9 0.0 7e-35 119.5 0.0 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GAM19980.1 - 1.4e-12 46.7 0.0 1e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 GAM19980.1 - 0.001 19.1 0.7 0.0019 18.2 0.0 1.8 2 0 0 2 2 2 1 Segregation and condensation protein ScpA Ras PF00071.22 GAM19981.1 - 2.7e-62 209.1 0.9 3.3e-62 208.9 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM19981.1 - 1.2e-34 119.1 0.2 2.4e-34 118.2 0.2 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM19981.1 - 1.8e-15 56.9 0.2 2.1e-15 56.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM19981.1 - 1.6e-06 28.2 0.2 2.9e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM19981.1 - 4.7e-06 26.6 0.2 0.071 13.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAM19981.1 - 5.5e-05 22.7 0.1 0.00013 21.5 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 GAM19981.1 - 5.8e-05 23.5 0.0 8.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 GAM19981.1 - 0.0036 17.0 0.3 0.0067 16.2 0.3 1.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAM19981.1 - 0.0087 16.0 0.8 0.45 10.4 0.8 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea TniB PF05621.11 GAM19981.1 - 0.0087 15.5 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 GAM19981.1 - 0.012 15.8 0.1 0.8 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM19981.1 - 0.023 15.3 0.8 8.6 6.9 0.1 2.5 1 1 1 2 2 2 0 AAA domain Septin PF00735.18 GAM19981.1 - 0.045 13.0 0.2 0.092 12.0 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_14 PF13173.6 GAM19981.1 - 0.16 12.0 0.6 2.6 8.1 0.1 2.4 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 GAM19981.1 - 0.31 11.5 1.8 1.1 9.8 1.9 1.9 1 1 0 1 1 1 0 ABC transporter CENP-T_C PF15511.6 GAM19982.1 - 1.7e-08 34.5 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 GAM19982.1 - 2.6e-05 24.3 0.0 3.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 GAM19982.1 - 0.00015 22.1 0.1 0.00019 21.7 0.2 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GAM19982.1 - 0.00059 20.1 0.0 0.0016 18.7 0.0 1.7 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM19982.1 - 0.0016 18.8 0.1 0.0021 18.4 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 GAM19982.1 - 0.0023 18.0 0.0 0.0029 17.7 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAM19982.1 - 0.0024 17.8 0.0 0.0098 15.9 0.0 1.8 1 1 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.16 GAM19982.1 - 0.065 13.3 0.1 0.14 12.2 0.1 1.5 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit POT1PC PF16686.5 GAM19983.1 - 0.00076 19.4 0.1 0.032 14.1 0.0 2.3 1 1 1 2 2 2 1 ssDNA-binding domain of telomere protection protein tRNA_anti-codon PF01336.25 GAM19983.1 - 0.023 14.7 0.1 0.5 10.4 0.0 2.8 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Pkinase_Tyr PF07714.17 GAM19984.1 - 5.9e-52 176.5 0.0 1.4e-51 175.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM19984.1 - 3.7e-43 147.8 0.0 2.1e-42 145.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain PH PF00169.29 GAM19984.1 - 1.3e-14 54.5 0.0 8.3e-14 52.0 0.0 2.5 2 1 0 2 2 2 1 PH domain PH_11 PF15413.6 GAM19984.1 - 0.014 15.8 2.6 0.21 12.0 2.6 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain Kdo PF06293.14 GAM19984.1 - 0.076 12.4 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pentapeptide_3 PF13576.6 GAM19986.1 - 1.5 9.1 10.1 15 5.9 0.8 4.5 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) DUF5427 PF10310.9 GAM19987.1 - 4.6 6.1 18.2 4.8 6.0 18.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Flavoprotein PF02441.19 GAM19988.1 - 8e-48 162.2 0.0 1e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein DUF2675 PF11247.8 GAM19988.1 - 0.13 12.4 0.1 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2675) EF-hand_7 PF13499.6 GAM19989.1 - 1.1e-17 64.2 9.5 1.3e-09 38.4 2.2 3.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 GAM19989.1 - 1.9e-16 58.3 18.5 2.7e-05 23.4 0.2 5.0 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 GAM19989.1 - 2.4e-16 58.2 10.8 0.00069 19.3 0.1 4.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 GAM19989.1 - 5.8e-13 47.7 14.2 0.00052 19.4 2.4 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAM19989.1 - 7.2e-12 45.0 13.9 2.6e-05 24.0 1.2 4.3 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM19989.1 - 0.0011 19.2 2.3 5.5 7.4 0.5 3.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.11 GAM19989.1 - 0.032 14.4 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 EF hand FNIP PF05725.12 GAM19990.1 - 2.3e-67 222.9 31.8 3.4e-13 49.5 0.2 8.7 6 1 3 9 9 9 9 FNIP Repeat DUF572 PF04502.13 GAM19990.1 - 0.68 9.5 18.7 1.2 8.7 18.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Beta-lactamase PF00144.24 GAM19991.1 - 0.032 13.5 0.2 0.11 11.7 0.1 1.7 1 1 1 2 2 2 0 Beta-lactamase GCIP PF13324.6 GAM19993.1 - 2.9e-55 187.7 8.3 6.2e-55 186.6 8.3 1.5 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting Rx_N PF18052.1 GAM19993.1 - 0.0037 17.5 2.0 0.93 9.8 0.0 3.3 4 0 0 4 4 4 1 Rx N-terminal domain T3SS_TC PF06511.11 GAM19993.1 - 0.02 14.3 0.9 0.036 13.5 0.9 1.4 1 0 0 1 1 1 0 Type III secretion systems tip complex components XRN_M PF17846.1 GAM19993.1 - 0.025 13.5 1.3 0.038 12.9 1.0 1.4 1 1 0 1 1 1 0 Xrn1 helical domain IFT20 PF14931.6 GAM19993.1 - 0.033 14.3 2.7 0.77 9.9 0.9 3.3 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 ER PF01133.17 GAM19993.1 - 0.081 12.9 0.1 3.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Enhancer of rudimentary SKA1 PF07160.12 GAM19993.1 - 0.12 12.2 1.6 0.8 9.5 0.3 2.6 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF4407 PF14362.6 GAM19993.1 - 0.23 10.8 1.8 0.36 10.1 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BUD22 PF09073.10 GAM19993.1 - 0.34 10.2 8.9 0.46 9.8 8.9 1.2 1 0 0 1 1 1 0 BUD22 Ribosomal_60s PF00428.19 GAM19993.1 - 0.34 11.5 6.3 0.88 10.2 6.3 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4820 PF16091.5 GAM19993.1 - 1.9 7.8 5.3 2.8 7.3 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FYDLN_acid PF09538.10 GAM19993.1 - 2.2 9.0 15.6 6.1 7.6 15.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RRN3 PF05327.11 GAM19993.1 - 5 5.6 10.2 8 4.9 10.2 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Gelsolin PF00626.22 GAM19994.1 - 5.3e-25 87.1 0.0 1.4e-06 28.1 0.0 5.6 5 0 0 5 5 5 5 Gelsolin repeat DUF5625 PF18539.1 GAM19994.1 - 0.11 12.8 0.4 0.62 10.4 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5625) Kinetochor_Ybp2 PF08568.10 GAM19995.1 - 5.3e-24 84.7 2.1 3.2e-14 52.4 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Spem1 PF15670.5 GAM19995.1 - 2.1 7.9 4.6 8.3 5.9 0.8 2.3 2 0 0 2 2 2 0 Spermatid maturation protein 1 Ras PF00071.22 GAM19996.1 - 1.4e-53 180.9 0.0 2.2e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM19996.1 - 4.6e-21 75.3 0.3 8.4e-21 74.4 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM19996.1 - 8.7e-08 31.8 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM19996.1 - 5.4e-06 26.1 1.2 0.00022 20.9 1.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM19996.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 GAM19996.1 - 0.0013 18.6 0.6 0.014 15.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.20 GAM19996.1 - 0.0016 17.7 1.4 0.58 9.3 0.4 2.9 1 1 1 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 GAM19996.1 - 0.0027 17.7 0.4 1.6 8.6 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase Spo12 PF05032.12 GAM19996.1 - 0.026 14.4 2.3 0.061 13.2 2.3 1.6 1 0 0 1 1 1 0 Spo12 family baeRF_family3 PF18845.1 GAM19996.1 - 0.039 14.2 0.0 0.058 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 FAM110_C PF14160.6 GAM19997.1 - 0.024 15.7 2.0 0.035 15.2 0.7 1.9 2 0 0 2 2 2 0 Centrosome-associated C terminus PI3Ka PF00613.20 GAM19998.1 - 5.2e-52 175.9 0.0 1.1e-51 174.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 GAM19998.1 - 2.1e-29 103.1 0.1 4.2e-28 98.8 0.1 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.18 GAM19998.1 - 7.3e-14 51.8 0.6 3.7e-08 33.5 0.0 2.7 2 0 0 2 2 2 2 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 GAM19998.1 - 2.1e-13 50.4 0.0 4.9e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 BacA PF02673.18 GAM19998.1 - 0.051 13.3 0.1 0.096 12.4 0.1 1.3 1 0 0 1 1 1 0 Bacitracin resistance protein BacA S10_plectin PF03501.15 GAM19999.1 - 5.7e-38 128.9 0.1 6.9e-38 128.6 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Amino_oxidase PF01593.24 GAM20000.1 - 2.2e-31 109.6 0.0 2.5e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM20000.1 - 9e-10 38.7 0.0 3e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAM20000.1 - 0.0016 18.4 0.0 0.07 13.1 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 GAM20000.1 - 0.047 13.3 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pkinase PF00069.25 GAM20001.1 - 2.7e-08 33.5 0.0 8.2e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 GAM20001.1 - 1.1e-06 28.4 0.1 0.15 12.4 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat Pkinase_Tyr PF07714.17 GAM20001.1 - 2.8e-06 26.8 0.0 5.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM20001.1 - 0.0043 16.4 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HEAT_EZ PF13513.6 GAM20001.1 - 0.01 16.3 0.0 11 6.7 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat Cnd1 PF12717.7 GAM20001.1 - 0.015 15.3 0.0 0.32 11.0 0.0 2.8 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAM20001.1 - 0.057 12.0 0.5 5.1 5.5 0.1 2.3 1 1 1 2 2 2 0 Adaptin N terminal region HEAT_2 PF13646.6 GAM20001.1 - 0.066 13.6 0.0 7.7 7.0 0.0 2.7 3 0 0 3 3 3 0 HEAT repeats Vac14_Fab1_bd PF12755.7 GAM20001.1 - 0.076 13.6 0.0 21 5.8 0.0 2.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region ESCRT-II PF05871.12 GAM20002.1 - 3.1e-46 157.1 2.8 4.1e-46 156.7 2.8 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit PAS_12 PF18095.1 GAM20002.1 - 0.03 14.0 0.2 0.064 12.9 0.1 1.6 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain MFS_1_like PF12832.7 GAM20003.1 - 3.3e-67 227.0 11.0 1.1e-66 225.3 11.0 1.6 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 GAM20003.1 - 3.7e-21 75.5 7.1 3.8e-20 72.1 5.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 GAM20003.1 - 4.1e-10 39.2 18.8 3.5e-05 23.0 8.3 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter DUF1772 PF08592.11 GAM20003.1 - 0.0087 16.4 0.5 0.069 13.5 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Ubiq_cyt_C_chap PF03981.12 GAM20004.1 - 1.2e-33 116.1 0.3 1.8e-33 115.6 0.3 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone PIH1_CS PF18201.1 GAM20005.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 PIH1 CS-like domain SHQ1 PF04925.15 GAM20006.1 - 7.5e-65 217.8 3.0 1.2e-64 217.1 3.0 1.3 1 0 0 1 1 1 1 SHQ1 protein Big_9 PF17963.1 GAM20007.1 - 0.00013 22.6 8.7 0.00013 22.6 8.7 8.0 8 2 0 8 8 8 3 Bacterial Ig domain PKD PF00801.20 GAM20007.1 - 0.00015 21.5 4.6 0.029 14.2 0.1 4.4 4 0 0 4 4 4 1 PKD domain Cadherin_3 PF16184.5 GAM20007.1 - 0.0015 18.5 1.6 0.59 10.2 0.1 3.7 3 0 0 3 3 3 1 Cadherin-like He_PIG PF05345.12 GAM20007.1 - 0.057 13.6 21.1 0.076 13.2 2.4 5.6 4 0 0 4 4 4 0 Putative Ig domain Laminin_EGF PF00053.24 GAM20007.1 - 6.7 6.9 23.5 50 4.2 14.7 2.8 1 1 1 2 2 2 0 Laminin EGF domain Cadherin_4 PF17803.1 GAM20007.1 - 6.9 7.4 33.0 0.024 15.3 4.0 5.9 6 0 0 6 6 6 0 Bacterial cadherin-like domain COX17 PF05051.13 GAM20008.1 - 6.2e-19 68.1 7.3 7.3e-19 67.9 7.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) RCSD PF05177.12 GAM20008.1 - 0.019 15.9 0.2 0.019 15.9 0.2 1.1 1 0 0 1 1 1 0 RCSD region CoA_trans PF01144.23 GAM20009.1 - 1.1e-113 378.0 2.1 1.4e-74 250.1 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 GAM20009.1 - 0.00047 20.1 0.2 0.075 13.0 0.0 2.3 2 0 0 2 2 2 2 Acetyl-CoA hydrolase/transferase C-terminal domain EGF_2 PF07974.13 GAM20010.1 - 6.7e-08 32.8 45.0 0.035 14.5 10.2 3.9 2 1 1 3 3 3 3 EGF-like domain TRP PF06011.12 GAM20010.1 - 0.00017 20.5 33.7 0.00042 19.2 27.4 3.4 1 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel Baculo_PEP_C PF04513.12 GAM20013.1 - 0.0062 16.6 2.0 0.056 13.5 1.8 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Ank_2 PF12796.7 GAM20014.1 - 1.9e-08 34.7 3.5 7.7e-05 23.2 0.6 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20014.1 - 2.6e-07 31.0 4.0 0.1 13.2 0.3 4.1 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20014.1 - 1.2e-06 28.3 1.4 3.2 8.6 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 GAM20014.1 - 4.6e-06 26.8 2.2 0.0048 17.2 0.0 3.4 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Viral_helicase1 PF01443.18 GAM20014.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SMK-1 PF04802.15 GAM20015.1 - 5.1e-66 222.2 10.3 5.1e-66 222.2 10.3 2.5 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 DUF4969 PF16339.5 GAM20015.1 - 1.5 9.2 4.7 2.9 8.3 2.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) MGAT2 PF05060.14 GAM20016.1 - 5.2e-60 203.4 13.8 7.8e-58 196.2 13.8 2.1 1 1 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) DENN PF02141.21 GAM20017.1 - 3.7e-26 92.2 8.3 6.9e-25 88.1 3.4 2.5 1 1 1 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 GAM20017.1 - 9.7e-09 35.9 1.2 1.7e-07 31.9 1.2 2.8 1 1 0 1 1 1 1 uDENN domain Avl9 PF09794.9 GAM20017.1 - 7.3e-07 28.2 1.9 1.2e-06 27.5 0.6 1.9 2 0 0 2 2 2 1 Transport protein Avl9 SPA PF08616.10 GAM20017.1 - 7.2e-05 22.7 1.9 0.00018 21.4 1.9 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis dDENN PF03455.19 GAM20017.1 - 0.16 11.9 1.0 0.8 9.7 0.1 2.4 2 0 0 2 2 2 0 dDENN domain Sua5_yciO_yrdC PF01300.18 GAM20018.1 - 3.6e-46 156.9 0.0 6.6e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 GAM20018.1 - 1.3e-12 48.4 0.0 1e-10 42.3 0.0 2.3 2 0 0 2 2 2 2 Putative GTP-binding controlling metal-binding Kelch_6 PF13964.6 GAM20019.1 - 1.3e-08 34.8 0.2 0.00017 21.7 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 GAM20019.1 - 0.0053 16.3 2.7 0.81 9.3 0.0 3.6 3 1 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAM20019.1 - 0.0059 16.5 0.9 0.64 10.1 0.1 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 GAM20019.1 - 0.018 15.0 8.2 0.71 9.9 0.3 3.5 4 1 0 4 4 4 0 Galactose oxidase, central domain DUF4807 PF16065.5 GAM20021.1 - 0.016 14.9 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) DUF2199 PF09965.9 GAM20021.1 - 0.034 14.2 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) GATase_5 PF13507.6 GAM20022.1 - 7.2e-97 323.5 0.0 1.2e-96 322.8 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 GAM20022.1 - 7e-31 107.5 2.1 3.3e-16 59.8 0.4 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 GAM20022.1 - 1.2e-19 70.4 0.1 2.6e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 GAM20022.1 - 5.9e-11 42.7 0.2 4.3e-10 40.0 0.1 2.4 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 GAM20022.1 - 0.014 16.0 0.1 0.33 11.6 0.0 2.8 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Pkinase_Tyr PF07714.17 GAM20023.1 - 1.6e-56 191.5 0.0 2.5e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM20023.1 - 2.5e-56 190.9 0.0 4.5e-56 190.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.19 GAM20023.1 - 6.9e-39 133.9 0.0 1.3e-38 132.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM20023.1 - 2.1e-20 72.9 0.3 4.7e-20 71.8 0.3 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Haspin_kinase PF12330.8 GAM20023.1 - 4.2e-05 22.7 1.8 4.4e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 GAM20023.1 - 0.013 14.9 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM20023.1 - 0.018 15.0 0.0 0.064 13.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM20023.1 - 0.076 12.6 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.6 GAM20023.1 - 0.11 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 GAM20023.1 - 0.31 9.8 2.1 0.23 10.2 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase NUC153 PF08159.12 GAM20024.1 - 1.3e-11 44.0 14.5 1.2e-09 37.8 1.5 4.8 4 0 0 4 4 4 3 NUC153 domain TPR_12 PF13424.6 GAM20025.1 - 3.2e-07 30.5 2.0 0.0099 16.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM20025.1 - 0.0014 18.5 0.7 2.6 8.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM20025.1 - 0.0018 18.3 5.5 0.43 10.8 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM20025.1 - 0.0074 15.7 0.1 0.024 14.0 0.1 1.8 1 1 0 1 1 1 1 MalT-like TPR region HhH-GPD PF00730.25 GAM20025.1 - 0.019 15.4 0.2 10 6.6 0.0 3.0 2 1 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein TPR_1 PF00515.28 GAM20025.1 - 0.045 13.6 4.8 4 7.4 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM20025.1 - 0.056 13.7 5.6 7 7.1 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM20025.1 - 0.22 11.4 4.1 1.6 8.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Big_9 PF17963.1 GAM20026.1 - 3.8e-08 34.0 17.1 1.1e-05 26.1 0.6 14.2 16 1 0 16 16 14 5 Bacterial Ig domain VWA PF00092.28 GAM20026.1 - 7.5e-08 32.8 0.1 1.5e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Cadherin_3 PF16184.5 GAM20026.1 - 4.9e-07 29.7 11.6 0.84 9.7 0.1 9.0 9 0 0 9 9 9 2 Cadherin-like Laminin_EGF PF00053.24 GAM20026.1 - 0.0058 16.7 18.0 0.011 15.9 9.4 2.4 1 1 1 2 2 2 1 Laminin EGF domain CHB_HEX_C_1 PF13290.6 GAM20026.1 - 0.082 12.9 8.4 0.21 11.6 0.3 5.0 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain AAA_lid_11 PF18198.1 GAM20026.1 - 0.088 12.6 0.1 0.38 10.6 0.1 2.0 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain VWA_3 PF13768.6 GAM20026.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain Integrin_b_cyt PF08725.11 GAM20026.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Fn3_assoc PF13287.6 GAM20026.1 - 0.17 12.1 2.5 9.3 6.5 0.3 3.7 3 0 0 3 3 3 0 Fn3 associated Cadherin_4 PF17803.1 GAM20026.1 - 0.24 12.1 68.4 0.021 15.4 2.8 10.5 8 1 1 9 9 8 0 Bacterial cadherin-like domain EGF_2 PF07974.13 GAM20026.1 - 1.8 9.0 27.4 0.49 10.8 7.3 2.8 3 0 0 3 3 2 0 EGF-like domain Cadherin_5 PF17892.1 GAM20026.1 - 6.6 6.8 43.8 0.23 11.5 0.8 10.2 12 2 0 12 12 11 0 Cadherin-like domain I-EGF_1 PF18372.1 GAM20026.1 - 6.9 6.9 17.9 4.9 7.3 7.1 2.6 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 GAM20026.1 - 7.4 7.0 14.5 1.6 9.1 4.4 2.7 2 0 0 2 2 2 0 EGF-like domain Big_9 PF17963.1 GAM20027.1 - 4.3e-17 62.6 140.0 1.3e-06 29.1 1.0 15.3 16 1 0 16 16 16 9 Bacterial Ig domain Laminin_EGF PF00053.24 GAM20027.1 - 0.014 15.5 17.7 0.064 13.4 9.9 2.6 1 1 1 2 2 2 0 Laminin EGF domain Cadherin_4 PF17803.1 GAM20027.1 - 0.018 15.7 0.7 0.018 15.7 0.7 11.7 10 1 0 10 10 10 0 Bacterial cadherin-like domain GRAM PF02893.20 GAM20028.1 - 5.3e-48 161.6 11.7 2.8e-21 75.5 0.1 5.9 5 1 0 5 5 5 4 GRAM domain Glyco_transf_28 PF03033.20 GAM20028.1 - 8.3e-24 84.2 0.0 1.8e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain FYVE PF01363.21 GAM20028.1 - 2.6e-12 46.7 4.5 5.3e-12 45.7 4.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 GAM20028.1 - 8.4e-12 45.5 2.5 8e-11 42.4 0.1 3.1 3 1 1 4 4 3 1 PH domain UDPGT PF00201.18 GAM20028.1 - 2.7e-08 33.0 0.0 8.1e-08 31.5 0.0 1.7 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_TFIIH PF08567.11 GAM20028.1 - 0.00037 20.8 0.0 5.8 7.3 0.0 4.7 6 0 0 6 6 4 1 TFIIH p62 subunit, N-terminal domain PH_11 PF15413.6 GAM20028.1 - 0.0012 19.2 0.3 0.0048 17.3 0.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Glyco_tran_28_C PF04101.16 GAM20028.1 - 0.011 15.7 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain FYVE_2 PF02318.16 GAM20028.1 - 0.015 15.5 4.1 0.041 14.1 4.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger bPH_3 PF14470.6 GAM20028.1 - 0.038 14.4 0.0 0.18 12.2 0.0 2.1 1 0 0 1 1 1 0 Bacterial PH domain SspB PF04386.13 GAM20028.1 - 0.062 13.2 2.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Stringent starvation protein B IBR PF01485.21 GAM20028.1 - 0.16 12.2 2.7 0.47 10.7 2.7 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PH_BEACH PF14844.6 GAM20028.1 - 0.18 11.9 1.7 16 5.6 0.0 3.7 4 0 0 4 4 3 0 PH domain associated with Beige/BEACH C1_1 PF00130.22 GAM20028.1 - 0.3 11.0 2.6 0.94 9.4 2.6 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC5 PF06221.13 GAM20028.1 - 0.31 11.1 5.2 0.047 13.7 0.6 2.0 2 0 0 2 2 1 0 Putative zinc finger motif, C2HC5-type C1_4 PF07975.12 GAM20028.1 - 0.41 10.9 5.9 1.1 9.5 5.9 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain zf-AN1 PF01428.16 GAM20028.1 - 0.84 9.8 7.8 4.9 7.4 8.0 2.1 1 1 1 2 2 2 0 AN1-like Zinc finger zf-B_box PF00643.24 GAM20028.1 - 1.2 9.4 4.3 3.8 7.7 4.3 1.9 1 0 0 1 1 1 0 B-box zinc finger zinc_ribbon_4 PF13717.6 GAM20028.1 - 2.4 8.1 5.2 5.7 7.0 5.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_5 PF14634.6 GAM20028.1 - 5.3 7.1 7.7 12 5.9 7.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain GNT-I PF03071.15 GAM20029.1 - 1.4e-73 248.1 6.6 4.8e-64 216.7 1.7 2.0 1 1 1 2 2 2 2 GNT-I family Baseplate PF16774.5 GAM20029.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Baseplate protein FAM193_C PF15914.5 GAM20029.1 - 0.14 11.9 0.2 0.42 10.4 0.2 1.8 1 0 0 1 1 1 0 FAM193 family C-terminal CTP_transf_like PF01467.26 GAM20030.1 - 2.6e-08 34.2 0.1 1.9e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Cytidylyltransferase-like Citrate_synt PF00285.21 GAM20031.1 - 1.5e-110 369.7 0.0 1.8e-110 369.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Ank_2 PF12796.7 GAM20032.1 - 2.8e-51 172.0 31.9 1.4e-10 41.6 0.6 6.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM20032.1 - 4.6e-43 144.7 23.1 0.0022 18.3 0.0 13.2 2 1 11 13 13 13 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM20032.1 - 2e-33 114.3 19.9 7.5e-06 26.4 0.2 9.2 3 3 8 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20032.1 - 4.1e-23 79.0 14.9 1.6 9.5 0.0 13.2 11 2 3 14 14 14 6 Ankyrin repeat DUF5049 PF16468.5 GAM20032.1 - 1.4e-10 40.9 3.7 16 5.5 0.0 9.9 7 4 4 11 11 11 1 Domain of unknown function (DUF5049) Ank PF00023.30 GAM20032.1 - 1.8e-05 25.0 14.3 14 6.3 0.4 9.2 6 1 2 8 8 8 1 Ankyrin repeat VHL_C PF17211.3 GAM20032.1 - 0.00021 21.2 0.1 55 3.9 0.0 6.6 9 0 0 9 9 9 0 VHL box domain AhpC-TSA PF00578.21 GAM20032.1 - 0.0048 16.8 0.0 6.9 6.6 0.0 3.8 2 1 2 4 4 4 1 AhpC/TSA family DUF5099 PF17025.5 GAM20032.1 - 0.06 13.7 0.0 30 5.1 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5099) TPP_enzyme_C PF02775.21 GAM20032.1 - 0.075 12.8 0.1 1.9 8.3 0.0 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Brix PF04427.18 GAM20033.1 - 3.4e-33 115.4 0.3 4.7e-33 114.9 0.3 1.2 1 0 0 1 1 1 1 Brix domain ADPrib_exo_Tox PF03496.14 GAM20033.1 - 0.037 13.4 0.6 0.055 12.8 0.6 1.2 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Rap_GAP PF02145.15 GAM20034.1 - 3.4e-23 82.2 0.1 6.2e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP RhoGAP PF00620.27 GAM20035.1 - 2.1e-29 102.3 0.7 1e-27 96.9 0.1 2.8 2 0 0 2 2 2 1 RhoGAP domain NRBF2 PF08961.10 GAM20035.1 - 4.3 6.9 13.7 0.37 10.4 3.1 3.0 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF1319 PF07028.11 GAM20036.1 - 0.12 12.6 3.8 2.1 8.6 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Spt20 PF12090.8 GAM20037.1 - 0.0007 19.3 13.7 0.0011 18.7 13.7 1.3 1 0 0 1 1 1 1 Spt20 family DUF4471 PF14740.6 GAM20037.1 - 0.055 12.7 4.8 0.086 12.1 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Pet20 PF08692.10 GAM20037.1 - 0.26 12.0 2.6 0.24 12.1 1.5 1.7 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Presenilin PF01080.17 GAM20037.1 - 0.38 9.5 4.5 0.43 9.3 4.5 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 GAM20037.1 - 0.52 11.3 10.5 0.98 10.4 10.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Flg_bb_rod PF00460.20 GAM20037.1 - 1.1 9.2 0.1 1.1 9.2 0.1 3.2 2 1 0 2 2 2 0 Flagella basal body rod protein ALMT PF11744.8 GAM20037.1 - 2.4 6.9 5.9 3.1 6.5 5.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Forkhead PF00250.18 GAM20039.1 - 0.0056 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain RVT_1 PF00078.27 GAM20040.1 - 9.1e-26 90.7 0.0 1.2e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SUIM_assoc PF16619.5 GAM20041.1 - 0.015 15.4 5.9 0.015 15.4 5.9 3.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Ammonium_transp PF00909.21 GAM20042.1 - 2.5e-111 372.2 23.4 2.9e-111 372.0 23.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Endotoxin_N PF03945.14 GAM20044.1 - 0.0038 17.0 0.4 0.019 14.7 0.0 2.3 2 1 1 3 3 3 1 delta endotoxin, N-terminal domain Mer2 PF09074.10 GAM20044.1 - 0.15 11.8 0.7 0.49 10.2 0.0 2.0 2 1 0 2 2 2 0 Mer2 Ribonuc_L-PSP PF01042.21 GAM20045.1 - 5.2e-37 126.5 0.1 6.3e-37 126.3 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP RPN13_C PF16550.5 GAM20045.1 - 0.076 13.2 0.0 1.4 9.1 0.0 2.1 1 1 1 2 2 2 0 UCH-binding domain Pilus_CpaD PF09476.10 GAM20045.1 - 0.092 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) UQ_con PF00179.26 GAM20046.1 - 2.8e-22 78.9 1.0 1.5e-21 76.6 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme TERB2 PF15101.6 GAM20046.1 - 0.084 12.9 6.8 0.13 12.3 6.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF908 PF06012.12 GAM20046.1 - 0.11 11.9 6.3 0.16 11.4 6.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Pex14_N PF04695.13 GAM20046.1 - 0.41 11.3 12.0 0.22 12.2 9.7 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SprA-related PF12118.8 GAM20046.1 - 0.94 8.6 15.3 1.3 8.1 15.3 1.1 1 0 0 1 1 1 0 SprA-related family FRQ PF09421.10 GAM20046.1 - 1 7.3 9.8 1.3 6.9 9.8 1.0 1 0 0 1 1 1 0 Frequency clock protein Spt20 PF12090.8 GAM20046.1 - 1.4 8.5 20.8 2.2 7.8 20.8 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 GAM20046.1 - 6.2 5.5 12.8 8.2 5.1 12.8 1.1 1 0 0 1 1 1 0 Androgen receptor DUF2967 PF11179.8 GAM20046.1 - 6.2 4.8 14.7 7.9 4.4 14.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) INT_SG_DDX_CT_C PF15300.6 GAM20047.1 - 0.00064 19.5 0.4 0.0012 18.6 0.4 1.5 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus DUF3402 PF11882.8 GAM20047.1 - 0.006 15.7 7.5 0.006 15.7 7.5 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3402) SARAF PF06682.12 GAM20047.1 - 0.28 10.8 11.4 21 4.7 0.0 2.7 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Folliculin PF11704.8 GAM20047.1 - 0.83 9.5 14.4 0.083 12.8 5.8 2.8 2 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport CIMR PF00878.18 GAM20048.1 - 5.3e-10 39.5 2.8 6.5e-08 32.8 1.2 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 GAM20048.1 - 7.1e-09 35.5 0.5 8e-09 35.4 0.5 1.4 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 GAM20048.1 - 8.3e-08 32.4 1.4 1.1e-07 32.0 1.4 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 MutS_V PF00488.21 GAM20051.1 - 1e-73 247.4 0.2 1.9e-73 246.5 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAM20051.1 - 8.5e-39 133.8 0.2 1.8e-38 132.7 0.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 GAM20051.1 - 1.9e-28 99.0 0.1 4.2e-28 97.9 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 GAM20051.1 - 7.7e-16 58.6 0.0 2.5e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 GAM20051.1 - 1.2e-09 38.4 3.0 3.8e-09 36.8 3.0 2.0 1 0 0 1 1 1 1 MutS family domain IV BNIP2 PF12496.8 GAM20051.1 - 0.063 13.7 1.6 0.17 12.3 1.6 1.8 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 YL1 PF05764.13 GAM20051.1 - 0.94 9.5 8.3 1.7 8.7 8.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein PBP1_TM PF14812.6 GAM20051.1 - 5.1 7.5 12.6 5 7.6 10.8 1.9 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PRELI PF04707.14 GAM20052.1 - 1.9e-26 92.8 0.7 2.5e-26 92.4 0.7 1.1 1 0 0 1 1 1 1 PRELI-like family Blt1_C PF17183.4 GAM20053.1 - 0.0023 17.5 0.1 0.083 12.5 0.1 2.3 2 0 0 2 2 2 1 Get5 carboxyl domain DUF3446 PF11928.8 GAM20053.1 - 0.0052 17.1 2.3 0.01 16.1 2.3 1.4 1 0 0 1 1 1 1 Early growth response N-terminal domain FAA_hydrolase_N PF09298.11 GAM20053.1 - 0.033 14.4 0.7 0.056 13.6 0.7 1.6 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal TipAS PF07739.13 GAM20053.1 - 0.035 14.6 0.1 0.058 13.9 0.1 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain GPHR_N PF12537.8 GAM20053.1 - 0.14 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal GET2 PF08690.10 GAM20053.1 - 0.4 10.3 6.5 0.49 10.0 6.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Secretin_N_2 PF07655.13 GAM20053.1 - 1.9 9.1 11.6 0.33 11.5 7.8 1.7 2 1 0 2 2 2 0 Secretin N-terminal domain Ribosomal_S3_C PF00189.20 GAM20054.1 - 8.4e-22 77.5 0.2 2e-21 76.3 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 GAM20054.1 - 1.5e-11 43.9 0.0 2.9e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 GAM20054.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus HMG_box PF00505.19 GAM20057.1 - 1.9e-17 63.4 2.1 5.9e-17 61.9 2.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAM20057.1 - 4.8e-11 43.1 1.5 4.8e-11 43.1 1.5 2.0 2 0 0 2 2 2 1 HMG-box domain Merozoite_SPAM PF07133.11 GAM20057.1 - 0.0024 17.9 12.3 0.0033 17.5 12.3 1.2 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) CDC45 PF02724.14 GAM20057.1 - 0.13 10.6 13.0 0.13 10.5 13.0 1.2 1 0 0 1 1 1 0 CDC45-like protein MATalpha_HMGbox PF04769.12 GAM20057.1 - 0.66 9.2 6.5 0.05 12.9 1.7 1.6 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 HMG-box Sporozoite_P67 PF05642.11 GAM20057.1 - 0.84 7.7 10.5 1.2 7.1 10.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YL1 PF05764.13 GAM20057.1 - 1.3 9.1 30.2 1.1 9.3 29.0 1.5 1 1 0 1 1 1 0 YL1 nuclear protein TFIIA PF03153.13 GAM20057.1 - 1.3 8.9 24.3 1.5 8.7 24.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YABBY PF04690.13 GAM20057.1 - 5.2 7.6 16.5 44 4.6 16.5 2.1 1 1 0 1 1 1 0 YABBY protein SAP PF02037.27 GAM20058.1 - 1e-10 41.1 0.9 2.4e-10 39.9 0.9 1.7 1 0 0 1 1 1 1 SAP domain Pkinase PF00069.25 GAM20059.1 - 2.9e-49 167.8 0.0 5.6e-49 166.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20059.1 - 1.1e-26 93.7 0.0 2.1e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 GAM20059.1 - 5.3e-23 81.0 10.5 7e-15 55.0 0.1 4.0 4 0 0 4 4 4 2 POLO box duplicated region Pkinase_fungal PF17667.1 GAM20059.1 - 1.6e-06 27.2 3.7 1.7e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAM20059.1 - 2.5e-06 27.0 0.8 4.7e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAM20059.1 - 0.1 12.5 0.1 0.2 11.5 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family TFIIA PF03153.13 GAM20059.1 - 1 9.3 16.2 0.34 10.9 13.7 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 GAM20060.1 - 2e-14 53.6 0.3 4.2e-14 52.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20060.1 - 0.00014 21.2 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase M20_dimer PF07687.14 GAM20060.1 - 0.036 14.0 1.0 0.058 13.3 1.0 1.5 1 1 0 1 1 1 0 Peptidase dimerisation domain LAMTOR5 PF16672.5 GAM20060.1 - 0.068 13.1 0.6 0.16 11.9 0.6 1.6 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 Ins_allergen_rp PF06757.13 GAM20060.1 - 0.19 11.7 1.7 0.29 11.1 1.7 1.2 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification TFIIA PF03153.13 GAM20060.1 - 0.78 9.7 15.9 0.81 9.6 15.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Steroid_dh PF02544.16 GAM20061.1 - 2.3e-23 82.9 3.9 3.1e-23 82.4 3.1 1.8 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase TPR_14 PF13428.6 GAM20062.1 - 2.6e-07 30.9 3.0 0.25 12.3 0.2 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM20062.1 - 1.4e-06 28.8 1.8 0.017 15.7 0.2 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM20062.1 - 2.8e-06 27.6 0.8 0.15 12.8 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM20062.1 - 1.5e-05 25.4 2.5 0.03 14.8 0.2 3.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM20062.1 - 1.8e-05 24.8 2.1 0.013 15.6 0.2 3.4 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM20062.1 - 3.8e-05 23.5 2.7 1.5 9.2 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM20062.1 - 6.2e-05 22.6 5.6 0.0067 16.2 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM20062.1 - 8.2e-05 22.8 1.1 0.0002 21.5 0.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GAM20062.1 - 0.00013 21.2 2.7 0.00037 19.8 1.2 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM20062.1 - 0.00018 21.4 1.9 2.2 8.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM20062.1 - 0.00067 19.9 1.5 0.61 10.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM20062.1 - 0.0046 16.4 1.7 0.057 12.8 2.6 2.1 2 1 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 GAM20062.1 - 0.02 14.9 0.1 4.6 7.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM20062.1 - 0.029 14.6 1.3 23 5.4 0.2 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat UvrD-helicase PF00580.21 GAM20062.1 - 0.045 13.3 0.3 0.072 12.6 0.3 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain TPR_20 PF14561.6 GAM20062.1 - 0.053 13.9 1.2 0.23 11.8 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 GAM20064.1 - 1.6e-06 28.2 0.2 2.2e-05 24.5 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase GBP PF02263.19 GAM20064.1 - 1.6e-06 27.6 0.0 3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain DUF2718 PF10918.8 GAM20064.1 - 0.031 14.8 0.9 0.092 13.3 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) Duffy_binding PF05424.11 GAM20064.1 - 0.034 14.2 1.9 0.21 11.6 0.1 2.3 2 0 0 2 2 2 0 Duffy binding domain Sedlin_N PF04628.13 GAM20064.1 - 0.29 11.3 2.6 0.34 11.0 0.2 2.1 2 0 0 2 2 2 0 Sedlin, N-terminal conserved region DUF2262 PF10020.9 GAM20065.1 - 0.15 12.5 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Methyltransf_25 PF13649.6 GAM20066.1 - 8.2e-09 36.1 0.0 1.8e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM20066.1 - 8.6e-08 32.8 0.0 2.6e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM20066.1 - 1.3e-07 31.7 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 GAM20066.1 - 2.4e-07 30.5 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.12 GAM20066.1 - 5e-05 23.9 0.0 0.0001 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM20066.1 - 0.00067 19.1 0.0 0.0012 18.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 GAM20066.1 - 0.0097 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) DOT1 PF08123.13 GAM20066.1 - 0.019 14.5 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Tim29 PF10171.9 GAM20067.1 - 0.067 12.7 0.1 0.88 9.0 0.0 2.1 1 1 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 VPS13 PF16908.5 GAM20068.1 - 1.5e-62 211.5 14.3 1.1e-61 208.7 1.0 4.3 5 0 0 5 5 5 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 GAM20068.1 - 1.8e-61 207.5 30.7 3e-53 180.7 5.2 6.9 7 0 0 7 7 7 4 Repeating coiled region of VPS13 VPS13_C PF16909.5 GAM20068.1 - 5.2e-53 179.4 13.5 1.7e-51 174.5 0.3 3.8 4 0 0 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 GAM20068.1 - 1.9e-39 135.7 0.4 3.2e-35 121.8 0.1 4.6 3 1 1 4 4 4 3 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 GAM20068.1 - 1.8e-26 92.5 0.7 1.8e-26 92.5 0.7 3.6 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 GAM20068.1 - 4.7e-09 36.5 0.0 1.7e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_hydro_35 PF01301.19 GAM20068.1 - 0.062 12.9 0.3 1.1 8.8 1.7 2.3 3 0 0 3 3 3 0 Glycosyl hydrolases family 35 SpoU_methylase PF00588.19 GAM20069.1 - 2.6e-33 115.2 0.0 4.1e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 GAM20069.1 - 3.6e-09 36.8 0.0 0.0016 18.7 0.0 2.4 2 0 0 2 2 2 2 RNA 2'-O ribose methyltransferase substrate binding SNARE PF05739.19 GAM20070.1 - 2.5e-12 46.6 1.2 2.5e-12 46.6 1.2 2.4 3 0 0 3 3 3 1 SNARE domain CheY-binding PF09078.11 GAM20070.1 - 0.027 14.6 0.1 0.091 12.9 0.1 1.9 1 0 0 1 1 1 0 CheY binding Syntaxin-5_N PF11416.8 GAM20070.1 - 0.052 12.8 0.3 0.052 12.8 0.3 2.5 3 0 0 3 3 3 0 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 GAM20070.1 - 0.066 12.9 15.0 0.56 9.8 0.1 3.3 2 1 1 3 3 3 0 Syntaxin UPF0242 PF06785.11 GAM20070.1 - 1.6 8.8 22.8 4.4 7.4 10.8 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Ank_2 PF12796.7 GAM20071.1 - 2.2e-09 37.8 0.4 0.00066 20.2 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) DUF249 PF03158.13 GAM20071.1 - 1.6e-05 24.7 0.2 0.00065 19.5 0.0 2.5 1 1 1 2 2 2 1 Multigene family 530 protein Ank_3 PF13606.6 GAM20071.1 - 0.0051 17.2 4.3 1.4e+02 3.6 0.0 7.0 8 0 0 8 8 8 0 Ankyrin repeat Ank_4 PF13637.6 GAM20071.1 - 0.0055 17.3 4.2 6.6 7.4 0.1 5.1 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Pho86 PF11124.8 GAM20071.1 - 0.026 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Ank_5 PF13857.6 GAM20071.1 - 0.11 12.9 0.2 1.4e+02 2.9 0.0 4.3 4 1 1 5 5 5 0 Ankyrin repeats (many copies) DUF3447 PF11929.8 GAM20071.1 - 0.28 11.2 1.8 2.4 8.2 0.9 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF3447) Ank_3 PF13606.6 GAM20072.1 - 1.4e-05 25.1 1.0 2 9.2 0.0 6.4 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 GAM20072.1 - 5.6e-05 23.6 2.8 0.01 16.4 0.2 4.1 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM20072.1 - 0.0076 16.8 1.7 1 10.0 0.0 4.3 3 1 3 6 6 6 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 GAM20072.1 - 0.1 12.6 0.8 2.9 7.9 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) Cyclin_N PF00134.23 GAM20073.1 - 7e-12 45.2 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAM20073.1 - 5.9e-09 36.5 0.0 1e-08 35.7 0.0 1.4 1 1 0 1 1 1 1 Cyclin Apolipoprotein PF01442.18 GAM20074.1 - 0.087 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain RPW8 PF05659.11 GAM20074.1 - 0.19 11.4 0.8 0.39 10.4 0.8 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Not3 PF04065.15 GAM20074.1 - 0.22 10.9 4.6 2.7 7.4 0.2 2.4 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Usp PF00582.26 GAM20076.1 - 4.1e-22 79.2 0.1 1.3e-20 74.3 0.1 2.1 1 1 0 1 1 1 1 Universal stress protein family PIG-L PF02585.17 GAM20076.1 - 0.093 13.4 0.1 0.14 12.8 0.1 1.4 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase RhoGEF PF00621.20 GAM20077.1 - 9.4e-42 143.3 6.5 9.4e-42 143.3 6.5 2.0 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 GAM20077.1 - 1.5e-11 44.4 0.0 4.6e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 GAM20077.1 - 0.00016 21.1 0.2 0.00037 20.0 0.2 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif IQ_SEC7_PH PF16453.5 GAM20077.1 - 0.0036 17.3 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PH PF00169.29 GAM20077.1 - 0.016 15.7 0.0 4.7 7.8 0.0 3.3 3 0 0 3 3 3 0 PH domain CPSase_L_D3 PF02787.19 GAM20077.1 - 0.15 12.4 2.4 1.9 8.9 0.0 2.9 3 0 0 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Ank_2 PF12796.7 GAM20079.1 - 0.0046 17.5 0.6 4.2 8.0 0.0 4.6 3 2 1 4 4 4 1 Ankyrin repeats (3 copies) GAS PF13851.6 GAM20080.1 - 0.37 10.1 1.4 0.59 9.5 1.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ank_3 PF13606.6 GAM20081.1 - 0.0086 16.5 2.9 51 4.9 0.0 5.7 7 0 0 7 7 7 1 Ankyrin repeat RhoGAP PF00620.27 GAM20083.1 - 2.5e-06 27.4 0.9 8.1e-06 25.7 0.9 1.9 1 0 0 1 1 1 1 RhoGAP domain MTS PF05175.14 GAM20084.1 - 6.5e-10 38.8 0.0 2.5e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GAM20084.1 - 6.3e-09 35.9 0.0 1.1e-08 35.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM20084.1 - 6.7e-08 33.1 0.0 1.1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAM20084.1 - 8.5e-08 31.9 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAM20084.1 - 4.7e-07 30.4 0.0 1.6e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM20084.1 - 7.1e-07 29.1 0.0 1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAM20084.1 - 1.3e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 GAM20084.1 - 0.0007 19.4 0.0 0.00078 19.2 0.0 1.3 1 1 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 GAM20084.1 - 0.001 18.8 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 GAM20084.1 - 0.0012 19.5 0.0 0.0021 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 GAM20084.1 - 0.0017 18.1 0.2 0.86 9.3 0.0 2.1 2 0 0 2 2 2 2 DNA methylase TehB PF03848.14 GAM20084.1 - 0.0017 17.8 0.0 0.0031 17.0 0.0 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB UPF0020 PF01170.18 GAM20084.1 - 0.0061 16.3 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.20 GAM20084.1 - 0.012 14.9 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase AAA_24 PF13479.6 GAM20085.1 - 0.02 14.6 1.0 0.045 13.5 1.0 1.6 1 0 0 1 1 1 0 AAA domain FERM_M PF00373.18 GAM20085.1 - 9.7 6.6 8.7 1.4e+02 2.9 8.7 2.6 1 1 0 1 1 1 0 FERM central domain PRCC PF10253.9 GAM20086.1 - 0.02 15.7 20.2 0.03 15.1 20.2 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF872 PF05915.12 GAM20086.1 - 0.044 13.9 2.0 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Hamartin PF04388.12 GAM20086.1 - 1.8 7.1 22.0 2.5 6.7 22.0 1.2 1 0 0 1 1 1 0 Hamartin protein vATP-synt_AC39 PF01992.16 GAM20087.1 - 5.3e-118 394.4 2.5 5.9e-118 394.2 2.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CH PF00307.31 GAM20088.1 - 2.6e-15 56.5 0.6 6.8e-15 55.2 0.1 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain Castor1_N PF18700.1 GAM20089.1 - 0.35 10.7 1.4 0.42 10.5 0.2 1.7 2 0 0 2 2 2 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain RPN13_C PF16550.5 GAM20090.1 - 1.9e-20 73.1 0.0 3.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 GAM20090.1 - 3.1e-17 62.9 0.1 5.2e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Rubella_E2 PF05749.11 GAM20090.1 - 0.5 9.8 3.0 0.84 9.0 3.0 1.3 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 RNA_pol_Rpb1_1 PF04997.12 GAM20091.1 - 5.9e-115 383.9 1.6 5.9e-115 383.9 1.6 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GAM20091.1 - 5.1e-107 357.3 0.0 5.1e-107 357.3 0.0 2.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAM20091.1 - 6.3e-77 257.5 1.6 7e-77 257.3 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 GAM20091.1 - 1.7e-58 197.6 0.0 3.4e-58 196.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 GAM20091.1 - 1.3e-48 164.9 0.0 3e-48 163.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 GAM20091.1 - 1.1e-39 135.6 5.3 4e-39 133.7 5.3 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 GAM20091.1 - 3.6e-37 126.6 0.9 3.6e-37 126.6 0.9 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 GAM20091.1 - 2.9e-10 39.9 285.9 0.38 11.2 16.2 13.6 5 1 10 18 18 18 15 RNA polymerase Rpb1 C-terminal repeat Pept_tRNA_hydro PF01195.19 GAM20092.1 - 1.5e-16 60.8 0.0 2.1e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Zip PF02535.22 GAM20094.1 - 2.3 7.4 3.7 3.2 6.9 3.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SNARE PF05739.19 GAM20095.1 - 1.1e-07 31.7 0.4 2e-07 30.9 0.4 1.5 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 GAM20095.1 - 0.00058 18.0 2.7 0.00063 17.9 2.2 1.5 1 1 1 2 2 2 1 Prominin Syntaxin_2 PF14523.6 GAM20095.1 - 0.0031 17.8 5.7 0.0071 16.7 2.3 2.3 2 0 0 2 2 2 1 Syntaxin-like protein NYD-SP28 PF14772.6 GAM20095.1 - 0.093 12.8 2.9 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Sperm tail PCRF PF03462.18 GAM20095.1 - 1.6 8.5 5.0 2.2 8.1 0.9 2.0 1 1 0 2 2 2 0 PCRF domain adh_short PF00106.25 GAM20096.1 - 2.4e-42 144.6 0.2 3.9e-42 143.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM20096.1 - 9e-21 74.5 0.0 1.1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM20096.1 - 4.1e-10 39.9 0.5 5.1e-09 36.3 0.5 2.0 1 1 0 1 1 1 1 KR domain A-2_8-polyST PF07388.11 GAM20096.1 - 0.021 13.4 0.3 0.028 13.0 0.3 1.1 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) Methyltr_RsmB-F PF01189.17 GAM20096.1 - 0.078 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Lactamase_B_6 PF16661.5 GAM20097.1 - 3.2e-16 59.3 0.5 1.1e-14 54.3 0.1 2.5 1 1 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 GAM20097.1 - 3.5e-08 33.0 0.1 4e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Putative beta-lactamase-like family Beta-Casp PF10996.8 GAM20097.1 - 1.7e-05 25.1 0.0 4.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain PA14 PF07691.12 GAM20098.1 - 4.3e-09 36.3 1.8 8.4e-09 35.4 1.8 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 GAM20098.1 - 3.3e-07 30.1 24.8 3.9e-05 23.5 6.8 13.2 13 2 0 13 13 13 7 Dictyostelium (slime mold) repeat OppC_N PF12911.7 GAM20098.1 - 0.069 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C STATa_Ig PF18214.1 GAM20099.1 - 3.2e-47 159.5 2.4 3.2e-47 159.5 2.4 2.9 3 0 0 3 3 3 1 STATa Immunoglobulin-like domain EF-hand_12 PF17901.1 GAM20099.1 - 4.5e-37 126.4 1.1 4.5e-37 126.4 1.1 3.0 3 0 0 3 3 3 1 EF-hand fold domain Dict-STAT-coil PF09267.10 GAM20099.1 - 2e-36 124.8 16.9 2e-36 124.8 16.9 4.1 4 0 0 4 4 4 1 Dictyostelium STAT, coiled coil SH2 PF00017.24 GAM20099.1 - 4.3e-11 42.8 0.0 1.4e-10 41.1 0.0 2.0 1 0 0 1 1 1 1 SH2 domain CLN3 PF02487.17 GAM20099.1 - 1.2 8.1 6.9 3.6 6.5 6.9 1.8 1 0 0 1 1 1 0 CLN3 protein EOS1 PF12326.8 GAM20099.1 - 1.2 9.1 3.3 3.7 7.4 3.3 1.8 1 0 0 1 1 1 0 N-glycosylation protein Folate_carrier PF01770.18 GAM20099.1 - 2.7 6.6 6.0 4.7 5.8 6.0 1.3 1 0 0 1 1 1 0 Reduced folate carrier EIIBC-GUT_N PF03612.14 GAM20099.1 - 4.5 7.0 10.6 18 5.0 10.6 2.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Apolipoprotein PF01442.18 GAM20100.1 - 0.0013 18.6 0.8 0.0019 18.1 0.8 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Streptin-Immun PF11083.8 GAM20100.1 - 0.012 16.0 5.5 0.022 15.2 5.5 1.5 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein Baculo_PEP_C PF04513.12 GAM20100.1 - 0.019 15.0 10.4 0.037 14.1 3.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 GAM20100.1 - 0.08 13.4 12.1 0.047 14.2 5.3 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Focal_AT PF03623.13 GAM20100.1 - 0.083 12.9 4.5 0.19 11.7 4.4 1.6 1 1 1 2 2 2 0 Focal adhesion targeting region Octopine_DH PF02317.17 GAM20100.1 - 0.099 12.7 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Bac_small_YrzI PF09501.10 GAM20100.1 - 0.1 12.8 0.0 0.1 12.8 0.0 2.6 4 1 0 4 4 4 0 Probable sporulation protein (Bac_small_yrzI) Phasin PF05597.11 GAM20100.1 - 0.12 12.4 4.5 0.21 11.6 4.5 1.4 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Chrome_Resist PF09828.9 GAM20100.1 - 0.21 12.0 1.6 1.9 8.9 0.4 2.0 1 1 1 2 2 2 0 Chromate resistance exported protein FadA PF09403.10 GAM20100.1 - 0.38 11.3 6.9 0.13 12.8 3.1 1.9 2 0 0 2 2 2 0 Adhesion protein FadA Laminin_II PF06009.12 GAM20100.1 - 0.39 10.7 7.9 2.3 8.3 7.4 1.9 1 1 1 2 2 2 0 Laminin Domain II Matrilin_ccoil PF10393.9 GAM20100.1 - 0.45 10.4 6.3 24 4.9 6.3 2.4 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin M PF02370.16 GAM20100.1 - 0.57 10.9 0.3 0.57 10.9 0.3 3.9 2 1 1 4 4 4 0 M protein repeat Fzo_mitofusin PF04799.13 GAM20100.1 - 0.69 9.5 7.0 0.35 10.4 2.6 2.0 1 1 1 2 2 2 0 fzo-like conserved region bZIP_1 PF00170.21 GAM20100.1 - 0.7 10.0 8.0 1.3 9.1 2.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor CdvA PF18822.1 GAM20100.1 - 0.88 9.4 8.5 0.35 10.7 4.2 2.0 1 1 0 2 2 2 0 CdvA-like coiled-coil domain HSBP1 PF06825.12 GAM20100.1 - 1.3 9.0 7.8 1.5 8.8 0.1 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 IFP_35_N PF07334.13 GAM20100.1 - 1.7 8.8 6.3 0.97 9.6 4.1 1.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus RPN1_RPN2_N PF17781.1 GAM20101.1 - 1.7e-115 385.7 0.5 2.2e-115 385.3 0.5 1.2 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 GAM20101.1 - 8.2e-29 99.4 0.0 2.1e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 GAM20101.1 - 4e-25 86.9 17.0 0.00096 19.5 0.0 10.0 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 GAM20101.1 - 3.4e-10 40.2 1.1 0.00078 19.8 0.0 4.8 4 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 GAM20101.1 - 2.1e-05 24.4 0.0 2.5 8.6 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 GAM20101.1 - 0.013 14.1 0.0 2.6 6.5 0.0 2.4 1 1 0 2 2 2 0 Adaptin N terminal region Pkinase PF00069.25 GAM20102.1 - 7.6e-43 146.8 0.0 8.5e-28 97.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20102.1 - 4.1e-27 95.1 0.0 3e-18 66.0 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAM20102.1 - 0.01 15.2 0.2 0.04 13.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 GAM20102.1 - 0.01 14.6 1.5 0.042 12.6 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 GAM20102.1 - 0.071 12.1 1.0 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Menin PF05053.13 GAM20102.1 - 0.14 10.5 3.4 0.18 10.1 3.4 1.2 1 0 0 1 1 1 0 Menin DUF1942 PF09167.11 GAM20102.1 - 0.23 11.4 3.0 0.52 10.3 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) Macoilin PF09726.9 GAM20102.1 - 2.2 6.7 6.6 3.1 6.2 6.6 1.2 1 0 0 1 1 1 0 Macoilin family COesterase PF00135.28 GAM20103.1 - 2.5e-100 336.8 1.0 3.3e-100 336.4 1.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM20103.1 - 1.3e-07 31.7 0.1 4.2e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM20103.1 - 0.018 14.5 0.0 0.044 13.2 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Sec63 PF02889.16 GAM20104.1 - 1.3e-25 90.0 0.9 1.7e-14 53.6 1.3 2.1 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 GAM20104.1 - 7.3e-20 70.9 0.1 1.9e-19 69.5 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain zf-LITAF-like PF10601.9 GAM20104.1 - 0.16 12.2 0.3 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Nucleo_P87 PF07267.11 GAM20104.1 - 2 7.2 10.6 3.3 6.4 10.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GRASP55_65 PF04495.14 GAM20105.1 - 3e-65 218.7 0.0 7.9e-46 155.8 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 GAM20105.1 - 0.0002 21.6 0.0 0.05 13.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain GHMP_kinases_N PF00288.26 GAM20106.1 - 5.7e-10 39.3 0.5 1e-09 38.5 0.5 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAM20106.1 - 0.0003 21.1 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal TFIIA PF03153.13 GAM20107.1 - 7.5 6.4 15.8 8.8 6.2 15.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RasGEF PF00617.19 GAM20108.1 - 8.2e-56 189.0 0.1 1.8e-55 187.9 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM20108.1 - 1.1e-20 73.8 1.0 3.3e-20 72.3 1.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif TetR_C_19 PF17924.1 GAM20108.1 - 0.53 10.9 3.1 2.2 8.9 0.1 3.1 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain AAA_16 PF13191.6 GAM20109.1 - 1.3e-09 38.6 0.0 5e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Tyosinase_C PF18132.1 GAM20109.1 - 0.13 12.9 2.6 0.54 10.9 1.2 2.8 2 0 0 2 2 2 0 Tyosinase C-terminal domain TPR_1 PF00515.28 GAM20110.1 - 3.3e-31 105.8 18.3 3.1e-08 33.1 0.3 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAM20110.1 - 7.1e-29 97.6 18.4 1.3e-06 28.1 0.2 7.8 9 0 0 9 9 7 4 Tetratricopeptide repeat DnaJ PF00226.31 GAM20110.1 - 4.8e-26 90.7 1.4 1.7e-25 88.9 1.4 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_8 PF13181.6 GAM20110.1 - 1.5e-18 65.3 23.0 9.7e-05 22.3 0.3 8.4 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM20110.1 - 6.9e-18 64.1 17.4 1.7e-06 27.6 0.2 7.2 4 1 3 7 7 7 4 TPR repeat TPR_19 PF14559.6 GAM20110.1 - 4.1e-13 49.6 15.5 8.5e-05 23.0 0.3 6.1 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM20110.1 - 1.8e-09 38.1 1.0 0.00011 22.8 0.0 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM20110.1 - 2.6e-09 37.1 0.1 0.088 13.7 0.0 6.2 4 1 2 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM20110.1 - 1.5e-08 34.1 1.1 0.24 11.5 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM20110.1 - 4.5e-07 30.1 9.3 0.043 14.1 1.2 6.1 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM20110.1 - 9.3e-06 25.7 13.7 7.6e-05 22.8 0.1 5.5 7 0 0 7 7 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM20110.1 - 2.3e-05 24.5 0.1 0.00048 20.2 0.1 3.0 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM20110.1 - 0.00021 21.0 3.1 0.6 10.1 0.2 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM20110.1 - 0.00022 20.5 12.4 0.14 11.4 8.0 4.0 1 1 2 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 GAM20110.1 - 0.00029 21.3 0.2 0.11 12.9 0.9 3.7 3 2 0 3 3 3 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 GAM20110.1 - 0.0044 17.2 19.2 0.085 13.1 0.2 5.5 2 1 3 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 GAM20110.1 - 0.016 15.2 13.9 0.037 14.1 0.0 5.7 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat HHH_8 PF14716.6 GAM20110.1 - 0.068 13.5 0.3 7.6 7.0 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain SPO22 PF08631.10 GAM20110.1 - 0.095 12.2 8.9 2 7.9 0.1 3.9 2 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like SHNi-TPR PF10516.9 GAM20110.1 - 0.61 9.6 6.2 24 4.5 0.1 4.3 4 0 0 4 4 4 0 SHNi-TPR MIT PF04212.18 GAM20110.1 - 0.63 10.1 14.6 1.4 9.0 0.2 5.2 4 2 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 GAM20110.1 - 0.9 10.3 17.8 0.69 10.7 0.3 6.5 8 1 0 8 8 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAM20110.1 - 4 7.8 11.6 12 6.3 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF1525 PF07511.11 GAM20110.1 - 10 6.3 6.9 2.3 8.4 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1525) Choline_transpo PF04515.12 GAM20111.1 - 2.6e-69 233.9 30.2 2.6e-69 233.9 30.2 2.5 2 1 0 2 2 2 2 Plasma-membrane choline transporter Adeno_100 PF02438.16 GAM20111.1 - 0.012 13.8 0.1 0.018 13.2 0.1 1.1 1 0 0 1 1 1 0 Late 100kD protein FGGY_N PF00370.21 GAM20112.1 - 6.1e-30 104.6 0.1 1.4e-15 57.6 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAM20112.1 - 3.4e-29 102.0 1.6 2.3e-22 79.7 1.3 2.3 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 GAM20112.1 - 0.0003 20.4 0.2 0.043 13.3 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family AnmK PF03702.14 GAM20112.1 - 0.036 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase Cnd1 PF12717.7 GAM20113.1 - 1.9e-09 37.8 13.9 7.9e-05 22.8 0.9 5.2 3 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM20113.1 - 0.00014 22.2 0.0 0.24 11.8 0.0 3.8 3 0 0 3 3 3 2 HEAT repeats RTP1_C1 PF10363.9 GAM20113.1 - 0.013 15.7 0.2 0.8 9.9 0.0 3.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 GAM20113.1 - 0.013 15.7 4.6 14 6.3 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 GAM20113.1 - 6.7 7.3 7.6 1.4e+02 3.1 0.0 5.9 7 0 0 7 7 7 0 HEAT-like repeat SMC_N PF02463.19 GAM20114.1 - 5.6e-53 179.6 18.3 1.4e-52 178.3 18.3 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAM20114.1 - 3.3e-21 75.8 0.0 1.4e-20 73.8 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 GAM20114.1 - 4.8e-17 63.1 9.8 4.8e-17 63.1 9.8 6.2 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 GAM20114.1 - 1.1e-13 51.7 13.2 7.4e-07 29.3 0.1 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAM20114.1 - 0.0019 18.0 32.0 0.0019 18.0 32.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 GAM20114.1 - 0.0061 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.9 GAM20114.1 - 0.0095 16.2 1.8 0.0095 16.2 1.8 8.6 5 3 1 8 8 8 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran PF00005.27 GAM20114.1 - 0.22 12.0 0.0 0.22 12.0 0.0 6.2 3 2 0 3 3 3 0 ABC transporter Kelch_6 PF13964.6 GAM20115.1 - 4.8e-14 52.0 2.2 4.5e-06 26.8 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAM20115.1 - 1.5e-08 34.5 1.5 0.00061 19.8 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM20115.1 - 1.9e-08 33.8 6.4 0.0032 17.0 0.0 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAM20115.1 - 6.1e-08 32.3 0.3 0.13 12.3 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 GAM20115.1 - 2e-05 24.5 7.0 0.21 11.6 0.1 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAM20115.1 - 0.059 13.7 0.4 24 5.4 0.0 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain Glyoxalase PF00903.25 GAM20116.1 - 3.1e-24 85.6 0.0 3.5e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAM20116.1 - 1.1e-09 38.5 0.0 3.8e-09 36.8 0.0 1.7 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GAM20116.1 - 1.5e-06 28.9 0.0 2.5e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 GAM20116.1 - 0.00041 20.3 0.0 0.00091 19.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 GAM20116.1 - 0.0013 18.8 0.0 0.0015 18.6 0.0 1.3 1 1 0 1 1 1 1 CppA N-terminal Glyoxalase_3 PF13468.6 GAM20116.1 - 0.0026 17.9 0.0 0.16 12.1 0.0 2.1 1 1 0 2 2 2 1 Glyoxalase-like domain Kelch_6 PF13964.6 GAM20117.1 - 4.3e-20 71.2 0.7 0.00032 20.9 0.0 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.6 GAM20117.1 - 4.1e-14 52.3 2.0 0.0016 18.4 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM20117.1 - 3.4e-10 39.3 2.3 0.005 16.4 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 GAM20117.1 - 3.6e-09 36.4 1.4 0.079 13.0 0.1 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 GAM20117.1 - 7.4e-06 25.7 4.6 0.6 10.2 0.1 4.6 4 1 1 5 5 4 3 Kelch motif Kelch_3 PF13415.6 GAM20117.1 - 5.2e-05 23.4 2.5 0.63 10.4 0.1 4.4 4 0 0 4 4 4 1 Galactose oxidase, central domain FlgN PF05130.12 GAM20117.1 - 0.004 17.7 0.9 0.8 10.2 0.1 2.3 2 0 0 2 2 2 1 FlgN protein zf-His_Me_endon PF05551.11 GAM20117.1 - 0.033 14.4 0.3 0.075 13.2 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease YlqD PF11068.8 GAM20117.1 - 0.034 14.5 1.3 0.034 14.5 1.3 1.8 2 0 0 2 2 2 0 YlqD protein PB1 PF00564.24 GAM20117.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.9 2 0 0 2 2 1 0 PB1 domain SAM_LFY PF01698.16 GAM20117.1 - 0.17 11.9 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein SAM domain Cwf_Cwc_15 PF04889.12 GAM20117.1 - 1.3 8.7 13.7 2.5 7.8 13.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GatB_Yqey PF02637.18 GAM20117.1 - 1.8 8.4 6.0 0.23 11.4 1.6 1.6 2 0 0 2 2 2 0 GatB domain SDA1 PF05285.12 GAM20117.1 - 6.8 6.0 13.8 9 5.6 13.8 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GAM20117.1 - 7.5 5.8 13.4 10 5.4 13.4 1.1 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 GAM20117.1 - 7.9 5.5 16.4 12 4.9 16.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GAM20117.1 - 9.3 4.2 20.9 12 3.8 20.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Kelch_4 PF13418.6 GAM20119.1 - 1.4e-13 50.6 2.4 3.4e-05 23.7 0.1 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM20119.1 - 9.2e-12 44.8 7.4 1.2e-06 28.6 0.1 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 GAM20119.1 - 2e-09 36.9 5.0 0.00064 19.3 0.0 3.7 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 GAM20119.1 - 3e-07 30.3 7.8 0.00078 19.4 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAM20119.1 - 2.1e-06 27.5 1.0 0.024 14.6 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 GAM20119.1 - 0.00039 20.6 2.5 2.2 8.6 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Laminin_EGF PF00053.24 GAM20120.1 - 4.8e-05 23.4 21.6 0.0039 17.3 0.7 3.4 3 0 0 3 3 3 2 Laminin EGF domain EB PF01683.18 GAM20120.1 - 0.11 12.8 25.3 0.038 14.3 10.0 3.5 3 0 0 3 3 3 0 EB module EGF_2 PF07974.13 GAM20120.1 - 3.2 8.2 18.7 11 6.5 9.4 3.2 2 0 0 2 2 2 0 EGF-like domain Kelch_6 PF13964.6 GAM20121.1 - 2.6e-11 43.4 6.0 0.00055 20.1 0.1 4.0 3 1 1 4 4 4 3 Kelch motif zf-B_box PF00643.24 GAM20121.1 - 1.6e-08 34.5 7.7 3.3e-08 33.5 7.7 1.5 1 0 0 1 1 1 1 B-box zinc finger Kelch_1 PF01344.25 GAM20121.1 - 7.9e-08 31.8 1.1 0.015 14.9 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAM20121.1 - 4.5e-07 29.8 5.3 0.21 11.6 0.1 3.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM20121.1 - 6.3e-05 22.9 2.3 0.37 10.8 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 GAM20121.1 - 0.0011 18.8 0.7 0.38 10.8 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 GAM20121.1 - 0.0087 16.3 5.5 4 7.8 0.2 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain IBR PF01485.21 GAM20121.1 - 9.5 6.5 9.2 0.73 10.1 3.7 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Syja_N PF02383.18 GAM20122.1 - 2e-84 283.6 0.5 2.7e-84 283.2 0.5 1.2 1 0 0 1 1 1 1 SacI homology domain S_4TM PF18159.1 GAM20122.1 - 2 7.6 8.2 2.8 7.2 0.6 2.7 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain F-actin_cap_A PF01267.17 GAM20123.1 - 1.3e-86 290.3 0.1 1.5e-86 290.1 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F_actin_cap_B PF01115.17 GAM20123.1 - 0.032 13.9 0.4 0.066 12.8 0.2 1.6 2 0 0 2 2 2 0 F-actin capping protein, beta subunit Glyco_transf_22 PF03901.17 GAM20124.1 - 3.4e-78 263.7 32.2 4.3e-78 263.4 32.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family NAD_kinase PF01513.21 GAM20126.1 - 9.6e-64 215.4 0.0 1.4e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GAM20126.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TPALS PF18178.1 GAM20126.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Acetyltransf_1 PF00583.25 GAM20127.1 - 2.8e-06 27.6 0.0 4.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM20127.1 - 1.5e-05 24.9 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM20127.1 - 0.002 18.5 0.1 0.0039 17.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM20127.1 - 0.0091 16.1 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Endotoxin_N PF03945.14 GAM20128.1 - 8.4e-13 48.5 0.6 1.6e-12 47.7 0.6 1.5 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.14 GAM20129.1 - 6.2e-17 62.1 3.2 1e-16 61.3 3.2 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Methyltrn_RNA_3 PF02598.17 GAM20130.1 - 1.3e-55 189.0 0.0 3.1e-55 187.7 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methyltransferase VIT PF08487.10 GAM20130.1 - 2e-28 98.8 0.0 2e-28 98.8 0.0 2.3 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 GAM20130.1 - 1.3e-26 93.4 0.0 1.2e-25 90.3 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 GAM20130.1 - 2.6e-13 50.6 0.0 1.5e-12 48.1 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM20130.1 - 5.1e-09 36.7 0.0 2.7e-08 34.4 0.0 2.4 3 0 0 3 3 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 GAM20130.1 - 3.8e-06 26.7 0.0 1.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 GAM20130.1 - 6.4e-06 25.7 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 GAM20130.1 - 0.00084 19.5 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus AIP3 PF03915.13 GAM20130.1 - 0.00087 18.5 7.4 0.0015 17.7 7.4 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Spc7 PF08317.11 GAM20130.1 - 0.013 14.4 10.7 0.024 13.5 10.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CobT_C PF11775.8 GAM20130.1 - 0.043 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Rx_N PF18052.1 GAM20130.1 - 0.054 13.8 1.7 0.15 12.3 1.7 1.7 1 0 0 1 1 1 0 Rx N-terminal domain DUF2201 PF09967.9 GAM20130.1 - 0.065 13.4 0.0 0.27 11.4 0.0 2.0 1 1 0 1 1 1 0 VWA-like domain (DUF2201) Atg14 PF10186.9 GAM20130.1 - 1.2 8.2 6.9 2.4 7.2 6.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 GAM20130.1 - 1.3 9.1 7.2 3.4 7.7 7.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 GAM20130.1 - 1.4 9.2 11.1 0.026 14.9 3.2 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Voltage_CLC PF00654.20 GAM20131.1 - 7e-65 219.6 31.7 4.9e-64 216.8 29.4 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 GAM20131.1 - 0.0021 18.4 0.1 0.0055 17.1 0.1 1.7 1 0 0 1 1 1 1 CBS domain Ham1p_like PF01725.16 GAM20132.1 - 5.6e-52 176.4 0.0 6.3e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family TIG PF01833.24 GAM20133.1 - 2.1e-06 27.7 23.5 0.025 14.7 0.6 6.1 5 3 1 6 6 6 4 IPT/TIG domain EB PF01683.18 GAM20133.1 - 0.18 12.1 5.0 0.43 10.9 5.0 1.5 1 0 0 1 1 1 0 EB module Med19 PF10278.9 GAM20134.1 - 1.1e-05 25.4 14.7 1.1e-05 25.4 14.7 2.4 1 1 1 2 2 2 1 Mediator of RNA pol II transcription subunit 19 TFIIA PF03153.13 GAM20134.1 - 0.00098 19.2 11.2 0.0012 18.9 11.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 GAM20134.1 - 0.011 14.5 11.8 0.014 14.2 11.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 GAM20134.1 - 0.064 12.9 10.3 0.11 12.1 10.3 1.6 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 GAM20134.1 - 0.16 10.8 9.5 0.23 10.3 9.5 1.3 1 0 0 1 1 1 0 Androgen receptor Rrp15p PF07890.12 GAM20134.1 - 9.4 6.6 15.0 4.1e+02 1.3 15.1 2.3 1 1 0 1 1 1 0 Rrp15p FYVE PF01363.21 GAM20135.1 - 1.7e-17 63.3 9.7 3.7e-17 62.2 9.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger DUF5349 PF17298.2 GAM20135.1 - 0.0014 18.5 19.5 0.0014 18.5 19.5 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5349) Arrestin_N PF00339.29 GAM20135.1 - 0.0019 18.3 0.1 0.0042 17.1 0.1 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SPX PF03105.19 GAM20135.1 - 0.0022 18.0 4.0 0.0022 18.0 4.0 1.7 2 0 0 2 2 2 1 SPX domain FYVE_2 PF02318.16 GAM20135.1 - 0.0073 16.5 7.5 0.013 15.7 7.5 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger Apt1 PF10351.9 GAM20135.1 - 0.11 11.3 12.2 0.026 13.4 9.0 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Menin PF05053.13 GAM20135.1 - 0.2 10.0 11.7 0.28 9.5 11.7 1.1 1 0 0 1 1 1 0 Menin zf-RING_2 PF13639.6 GAM20135.1 - 1.2 9.6 11.3 3.6 8.0 11.4 1.9 1 1 0 1 1 1 0 Ring finger domain Lin-8 PF03353.15 GAM20135.1 - 1.3 8.5 7.7 2.8 7.4 7.7 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCDC24 PF15669.5 GAM20135.1 - 1.4 8.7 7.8 2.7 7.8 7.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family ALMT PF11744.8 GAM20135.1 - 2.2 7.0 5.0 3.5 6.4 5.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4834 PF16118.5 GAM20135.1 - 2.2 9.3 4.0 6.6 7.8 4.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) zf-RING_5 PF14634.6 GAM20135.1 - 2.4 8.2 12.0 5 7.2 12.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Macoilin PF09726.9 GAM20135.1 - 6.3 5.2 18.5 0.069 11.7 11.0 1.4 2 0 0 2 2 2 0 Macoilin family Serendipity_A PF05482.12 GAM20135.1 - 8.6 4.9 9.1 13 4.3 9.1 1.1 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) Kelch_6 PF13964.6 GAM20136.1 - 1.7e-12 47.2 0.1 0.0022 18.2 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 GAM20136.1 - 1.6e-11 44.0 1.1 8.7e-06 25.7 0.1 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM20136.1 - 4.6e-09 35.7 0.0 0.00014 21.4 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 GAM20136.1 - 4.7e-07 29.7 4.9 0.03 14.3 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAM20136.1 - 2.9e-06 27.0 0.7 3.1 7.9 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAM20136.1 - 6.7e-06 26.3 0.4 2.9 8.3 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM20137.1 - 6.1e-17 61.2 1.6 8.6e-06 25.9 0.1 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAM20137.1 - 2.7e-11 42.9 2.6 0.002 17.6 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAM20137.1 - 1.1e-08 34.9 9.7 3.9e-06 26.8 0.1 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM20137.1 - 3.4e-05 23.7 6.1 0.19 11.8 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 GAM20137.1 - 0.00016 21.6 6.6 1.3 9.1 0.1 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAM20137.1 - 0.00031 21.0 1.4 0.16 12.3 0.0 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain DUF1241 PF06840.11 GAM20138.1 - 0.05 13.3 0.1 0.051 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Peptidase_A22B PF04258.13 GAM20140.1 - 3.7e-29 102.1 4.5 4.3e-29 101.9 4.5 1.0 1 0 0 1 1 1 1 Signal peptide peptidase Peptidase_A22B PF04258.13 GAM20141.1 - 0.00011 21.8 1.4 0.00019 21.1 1.4 1.4 1 0 0 1 1 1 1 Signal peptide peptidase DEAD PF00270.29 GAM20142.1 - 8.7e-35 120.1 3.4 1.1e-34 119.7 0.2 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM20142.1 - 1.6e-27 96.1 0.0 1.4e-26 93.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ADP_ribosyl_GH PF03747.14 GAM20142.1 - 0.6 9.8 6.1 1.2 8.8 3.7 2.3 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase Trp_oprn_chp PF09534.10 GAM20142.1 - 2.2 8.0 11.5 0.065 13.0 4.9 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4632 PF15451.6 GAM20142.1 - 4.2 7.5 9.6 0.37 10.9 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) K_channel_TID PF07941.11 GAM20142.1 - 6.9 7.2 14.5 7 7.2 10.8 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Shadoo PF14999.6 GAM20142.1 - 8.1 6.6 7.6 6.3 6.9 2.9 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF4506 PF14958.6 GAM20143.1 - 6.6e-12 45.1 1.2 6.6e-12 45.1 1.2 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4506) RdRP PF05183.12 GAM20144.1 - 9.4e-128 427.4 0.0 1.9e-127 426.4 0.0 1.5 1 0 0 1 1 1 1 RNA dependent RNA polymerase Helicase_C PF00271.31 GAM20144.1 - 1.2e-15 57.8 0.1 6.1e-15 55.5 0.1 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM20144.1 - 7.4e-14 52.1 0.0 2.1e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM20144.1 - 1.8e-12 47.4 0.1 4.8e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Adenyl_cycl_N PF12633.7 GAM20144.1 - 0.021 14.8 0.1 0.077 12.9 0.0 2.0 2 0 0 2 2 2 0 Adenylate cyclase NT domain NTP_transf_2 PF01909.23 GAM20144.1 - 0.053 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Lysine_decarbox PF03641.14 GAM20145.1 - 0.19 11.8 0.0 5 7.2 0.0 2.3 2 0 0 2 2 2 0 Possible lysine decarboxylase Asp PF00026.23 GAM20147.1 - 4.9e-111 371.1 0.2 5.8e-111 370.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM20147.1 - 2.4e-12 47.5 1.2 1.2e-10 41.9 1.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAM20147.1 - 0.00081 19.2 0.0 0.003 17.4 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAM20147.1 - 0.082 13.6 0.5 1.7 9.3 0.1 3.1 3 1 0 3 3 3 0 Aspartyl protease ArfGap PF01412.18 GAM20148.1 - 2e-10 40.8 0.1 2e-10 40.8 0.1 3.5 3 1 1 4 4 4 1 Putative GTPase activating protein for Arf Endonuclease_7 PF02945.15 GAM20148.1 - 0.04 13.8 1.6 0.1 12.5 1.6 1.6 1 0 0 1 1 1 0 Recombination endonuclease VII MoaE PF02391.17 GAM20149.1 - 3.7e-36 123.8 0.1 5.3e-36 123.3 0.1 1.2 1 0 0 1 1 1 1 MoaE protein DUF5424 PF17462.2 GAM20149.1 - 0.025 14.5 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5424) BOP1NT PF08145.12 GAM20150.1 - 6.8e-95 317.9 13.2 6.8e-95 317.9 13.2 2.5 2 1 1 3 3 3 1 BOP1NT (NUC169) domain WD40 PF00400.32 GAM20150.1 - 1.5e-26 92.1 0.3 5e-11 43.0 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM20150.1 - 5.5e-09 36.2 0.3 6.1e-07 29.7 0.1 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM20150.1 - 0.00064 19.7 0.2 1.5 8.7 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 GAM20150.1 - 0.0024 17.0 1.2 0.27 10.2 0.3 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Cellulose_synt PF03552.14 GAM20150.1 - 3.1 6.2 4.9 4.6 5.6 4.9 1.3 1 0 0 1 1 1 0 Cellulose synthase Myosin_TH1 PF06017.13 GAM20151.1 - 2.3e-35 122.0 6.6 3.6e-34 118.1 3.3 2.1 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding hSac2 PF12456.8 GAM20151.1 - 0.0047 16.6 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase GCM PF03615.15 GAM20151.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 GCM motif protein VWA_3 PF13768.6 GAM20152.1 - 5.2e-23 81.7 0.0 1.3e-22 80.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain MIF4G PF02854.19 GAM20152.1 - 4e-22 78.9 9.4 4e-22 78.9 9.4 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 GAM20152.1 - 7.8e-18 64.5 2.9 1.2e-17 63.9 0.5 2.7 2 0 0 2 2 2 1 MA3 domain VWA PF00092.28 GAM20152.1 - 5.9e-13 49.4 0.0 1.9e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM20152.1 - 7e-12 46.0 0.0 2.2e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 GAM20152.1 - 4e-09 36.7 0.3 1.9e-08 34.5 0.1 2.2 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain Symplekin_C PF12295.8 GAM20152.1 - 0.02 15.0 0.5 0.1 12.7 0.0 2.4 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal VWA_CoxE PF05762.14 GAM20152.1 - 0.021 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 GAM20152.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus Med25_VWA PF11265.8 GAM20153.1 - 1.6e-18 67.3 0.0 4.4e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Pkinase_Tyr PF07714.17 GAM20154.1 - 8.5e-35 120.3 0.0 1.4e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM20154.1 - 2.2e-31 109.2 0.0 4.3e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 GAM20154.1 - 3.2e-07 30.2 3.4 0.00034 20.5 0.1 4.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 GAM20154.1 - 0.04 13.4 12.3 0.036 13.5 8.1 2.8 2 1 1 3 3 3 0 Armadillo-like RWP-RK PF02042.15 GAM20155.1 - 9.8e-07 28.7 0.5 2.2e-06 27.5 0.5 1.6 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 GAM20155.1 - 0.031 14.1 0.1 0.069 13.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_psq PF05225.16 GAM20155.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF1462 PF07315.11 GAM20155.1 - 0.2 12.0 1.7 0.4 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) PGA2 PF07543.12 GAM20155.1 - 0.69 9.9 9.1 0.074 13.0 4.5 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 Glyco_hydro_18 PF00704.28 GAM20156.1 - 2.4e-08 34.1 0.1 2.3e-07 30.9 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Peptidase_M1 PF01433.20 GAM20156.1 - 0.23 11.0 1.0 0.36 10.4 1.0 1.2 1 0 0 1 1 1 0 Peptidase family M1 domain Pkinase PF00069.25 GAM20157.1 - 2.8e-29 102.3 0.0 4.6e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20157.1 - 4.9e-18 65.3 0.1 2.1e-17 63.3 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 GAM20157.1 - 3.7e-10 40.1 0.3 1e-09 38.6 0.3 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Kdo PF06293.14 GAM20157.1 - 0.0051 16.2 1.3 0.008 15.6 0.4 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM20157.1 - 0.024 14.2 0.2 0.057 13.0 0.2 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 GAM20157.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family NST1 PF13945.6 GAM20157.1 - 8.6 6.4 13.8 5.1 7.2 3.1 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Pkinase PF00069.25 GAM20158.1 - 2.1e-39 135.5 0.1 4.6e-39 134.4 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20158.1 - 8.2e-27 94.1 0.0 2.5e-26 92.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 GAM20158.1 - 4.7e-17 62.3 5.9 1e-16 61.3 5.9 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Kdo PF06293.14 GAM20158.1 - 4.9e-05 22.8 0.4 0.00012 21.6 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM20158.1 - 0.0011 18.7 0.2 0.0033 17.1 0.2 1.8 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAM20158.1 - 0.066 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3445 PF11927.8 GAM20158.1 - 2.2 7.8 6.4 2.6 7.6 0.4 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3445) Endotoxin_N PF03945.14 GAM20159.1 - 1.2e-37 129.8 0.0 1.9e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.14 GAM20160.1 - 2.8e-40 138.4 0.1 4.8e-40 137.6 0.1 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_C PF03944.14 GAM20161.1 - 0.013 15.8 0.1 0.017 15.5 0.1 1.1 1 0 0 1 1 1 0 delta endotoxin MSP PF01716.18 GAM20161.1 - 0.064 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide Endotoxin_N PF03945.14 GAM20163.1 - 2.2e-43 148.6 0.6 2.7e-43 148.2 0.6 1.1 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.14 GAM20164.1 - 7.1e-38 130.5 0.0 1.3e-37 129.7 0.0 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Pkinase PF00069.25 GAM20165.1 - 7.4e-39 133.7 0.0 1.6e-38 132.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20165.1 - 2e-26 92.8 0.0 3.8e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 GAM20165.1 - 5.5e-15 55.7 4.9 5.5e-15 55.7 4.9 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Kdo PF06293.14 GAM20165.1 - 0.00012 21.5 0.1 0.00026 20.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM20165.1 - 0.0011 18.6 0.1 0.0032 17.1 0.1 1.7 1 0 0 1 1 1 1 RIO1 family ZnuA PF01297.17 GAM20165.1 - 0.0038 16.7 0.1 0.013 14.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-uptake complex component A periplasmic Kinase-like PF14531.6 GAM20165.1 - 0.019 14.3 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GAM20165.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3963 PF13124.6 GAM20165.1 - 0.36 10.8 1.7 0.97 9.5 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Pkinase_fungal PF17667.1 GAM20165.1 - 6 5.5 12.6 8.3 5.1 10.1 2.3 2 1 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 GAM20167.1 - 6.5e-38 130.6 0.0 6.5e-38 130.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20167.1 - 2.7e-26 92.4 0.0 4.4e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 GAM20167.1 - 0.00016 21.8 4.1 0.0091 16.2 0.5 2.6 1 1 1 2 2 2 2 Ribonuclease 2-5A Kdo PF06293.14 GAM20167.1 - 0.00035 20.0 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM20167.1 - 0.0039 16.8 0.1 0.012 15.2 0.1 1.8 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 GAM20167.1 - 0.045 13.1 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GAM20167.1 - 0.068 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family G-alpha PF00503.20 GAM20168.1 - 1.4e-87 294.2 5.3 1.8e-87 293.8 5.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM20168.1 - 2.8e-12 46.4 0.1 6.4e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family EHN PF06441.12 GAM20168.1 - 0.096 13.1 1.0 0.48 10.8 0.1 2.3 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Rad60-SLD PF11976.8 GAM20169.1 - 5.8e-22 77.3 0.0 7.1e-22 77.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAM20169.1 - 1.2e-12 47.4 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family C2-C2_1 PF11618.8 GAM20170.1 - 0.024 14.7 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 SOG2 PF10428.9 GAM20170.1 - 3 7.0 20.2 0.32 10.2 8.2 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein RrnaAD PF00398.20 GAM20171.1 - 1.6e-64 217.5 0.1 1.9e-64 217.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 GAM20171.1 - 1.3e-08 35.5 0.0 2.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM20171.1 - 4.5e-06 27.2 0.0 8.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAM20171.1 - 0.00026 20.4 0.0 0.00082 18.7 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 GAM20171.1 - 0.00028 20.7 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 GAM20171.1 - 0.00032 21.4 0.0 0.00075 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 GAM20171.1 - 0.00053 19.6 0.0 0.00093 18.9 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 GAM20171.1 - 0.0022 17.8 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAM20171.1 - 0.0059 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM20171.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 GAM20171.1 - 0.0069 15.5 0.0 0.015 14.4 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase Ubie_methyltran PF01209.18 GAM20171.1 - 0.0084 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAM20171.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 GAM20171.1 - 0.016 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_2 PF00891.18 GAM20171.1 - 0.023 14.0 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Met_10 PF02475.16 GAM20171.1 - 0.031 14.0 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 GAM20171.1 - 0.031 13.7 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 GAM20171.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PRMT5 PF05185.16 GAM20171.1 - 0.049 13.5 0.1 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Homeodomain PF00046.29 GAM20172.1 - 1.2e-19 69.9 4.3 2.1e-19 69.1 4.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAM20172.1 - 0.0027 17.6 0.3 0.0055 16.6 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Glu-tRNAGln PF02686.15 GAM20173.1 - 5.9e-09 36.1 0.0 8.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Sds3 PF08598.11 GAM20174.1 - 4.1e-18 66.2 18.1 4.1e-18 66.2 18.1 2.5 2 1 1 3 3 3 2 Sds3-like Glu_cyclase_2 PF05096.12 GAM20174.1 - 0.0094 15.4 0.9 0.014 14.8 0.9 1.2 1 0 0 1 1 1 1 Glutamine cyclotransferase CBM49 PF09478.10 GAM20175.1 - 1.2e-06 28.7 0.4 1.7e-06 28.3 0.4 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Pkinase_Tyr PF07714.17 GAM20176.1 - 7.2e-68 228.7 0.0 1e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM20176.1 - 6.1e-58 196.3 0.0 1e-57 195.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kelch_3 PF13415.6 GAM20176.1 - 4.3e-30 103.4 11.2 1.3e-10 41.3 0.0 7.2 7 0 0 7 7 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM20176.1 - 1.9e-26 91.5 1.7 0.00043 20.2 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 GAM20176.1 - 3.8e-26 90.4 7.2 4.4e-06 26.2 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GAM20176.1 - 3.7e-25 87.7 10.3 2.4e-09 37.1 0.1 6.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM20176.1 - 4.5e-25 87.1 8.7 2.1e-05 24.6 0.0 6.7 6 1 1 7 7 6 5 Kelch motif Kelch_2 PF07646.15 GAM20176.1 - 1.5e-22 78.6 9.3 7.7e-07 28.9 0.0 6.9 7 0 0 7 7 6 3 Kelch motif Haspin_kinase PF12330.8 GAM20176.1 - 0.0093 14.9 1.4 0.16 10.9 1.4 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM20176.1 - 0.01 15.2 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RAG2 PF03089.14 GAM20176.1 - 0.068 12.1 0.0 0.33 9.9 0.0 2.0 2 0 0 2 2 2 0 Recombination activating protein 2 Pkinase_fungal PF17667.1 GAM20176.1 - 0.11 11.2 2.6 0.064 12.0 0.2 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 GAM20176.1 - 0.13 11.6 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FATC PF02260.20 GAM20176.1 - 0.13 12.1 0.3 0.29 11.0 0.3 1.5 1 0 0 1 1 1 0 FATC domain Serglycin PF04360.12 GAM20176.1 - 0.24 11.3 2.1 0.53 10.2 2.1 1.5 1 0 0 1 1 1 0 Serglycin Chordopox_L2 PF05803.12 GAM20177.1 - 0.07 13.0 1.2 0.15 11.9 1.2 1.6 1 0 0 1 1 1 0 Chordopoxvirus L2 protein DUF2254 PF10011.9 GAM20177.1 - 8.2 5.1 6.5 3.9 6.2 2.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Endotoxin_N PF03945.14 GAM20178.1 - 1.2e-34 120.0 0.1 2e-34 119.2 0.1 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Pkinase PF00069.25 GAM20179.1 - 3.5e-39 134.8 0.0 5.7e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20179.1 - 9.6e-29 100.4 0.0 1.6e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 GAM20179.1 - 3.6e-17 62.7 5.1 7.1e-17 61.8 5.1 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Kdo PF06293.14 GAM20179.1 - 3.4e-05 23.3 0.0 6.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM20179.1 - 0.0031 17.1 0.2 0.0078 15.8 0.2 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAM20179.1 - 0.14 12.1 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 GAM20180.1 - 1.5e-38 132.7 0.0 2.7e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20180.1 - 7.4e-26 91.0 0.0 1.2e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 GAM20180.1 - 6.4e-15 55.4 3.9 1.7e-14 54.1 3.9 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Kdo PF06293.14 GAM20180.1 - 0.00058 19.3 0.1 0.0013 18.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM20180.1 - 0.0037 16.9 0.2 0.0037 16.9 0.2 1.8 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 GAM20180.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GAM20180.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 GAM20181.1 - 2.7e-34 118.8 0.0 5.9e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20181.1 - 1.6e-21 76.8 0.0 5.7e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 GAM20181.1 - 1.8e-16 60.5 4.7 4e-16 59.3 4.7 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A DUF3384 PF11864.8 GAM20181.1 - 0.00043 19.3 0.1 0.00043 19.3 0.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) Kdo PF06293.14 GAM20181.1 - 0.0023 17.3 0.1 0.0045 16.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM20181.1 - 0.007 16.0 0.3 0.016 14.8 0.3 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAM20181.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family UvrA_inter PF17760.1 GAM20181.1 - 0.26 11.4 1.9 0.91 9.6 0.1 2.5 2 1 0 2 2 2 0 UvrA interaction domain Pkinase PF00069.25 GAM20182.1 - 1.3e-39 136.2 1.4 1.6e-39 135.9 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20182.1 - 3.4e-26 92.1 0.0 6.9e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 GAM20182.1 - 1.7e-16 60.6 4.7 1.7e-16 60.6 4.7 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Kdo PF06293.14 GAM20182.1 - 0.0012 18.3 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM20182.1 - 0.0087 15.7 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAM20182.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.27 GAM20183.1 - 2.9e-70 232.3 0.4 2.3e-24 85.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_2 PF07719.17 GAM20184.1 - 1.1e-19 68.9 18.5 1.7e-05 24.5 0.3 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAM20184.1 - 1.6e-17 62.5 21.2 2.7e-08 33.3 0.8 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM20184.1 - 2.9e-09 36.5 13.9 5.8e-05 22.7 0.3 4.0 5 0 0 5 5 4 3 TPR repeat TPR_12 PF13424.6 GAM20184.1 - 3e-09 37.0 10.4 3.9e-05 23.9 0.4 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM20184.1 - 3.1e-09 36.3 19.5 6e-05 22.9 0.3 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM20184.1 - 1e-06 29.3 0.3 0.017 15.8 0.3 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM20184.1 - 1.7e-06 27.7 2.9 0.013 15.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 GAM20184.1 - 3.8e-06 26.9 11.6 0.0029 17.6 1.2 4.4 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 GAM20184.1 - 3e-05 24.4 0.9 2.5 8.7 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM20184.1 - 5e-05 23.8 0.1 4.7 8.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 GAM20184.1 - 0.00018 21.4 14.5 0.26 11.3 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM20184.1 - 0.0021 18.0 1.9 18 5.7 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM20184.1 - 0.0027 18.2 4.8 11 6.9 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM20184.1 - 0.0035 17.4 4.8 0.43 10.7 0.1 4.0 2 1 2 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 GAM20184.1 - 0.011 15.9 12.5 0.25 11.6 2.1 3.4 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAM20184.1 - 0.014 15.7 4.7 7 7.3 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 GAM20184.1 - 0.14 12.2 9.1 0.25 11.4 0.9 4.1 3 1 2 5 5 5 0 Domain of Unknown Function (DUF3856) RTP1_C2 PF10304.9 GAM20184.1 - 1.3 8.7 5.6 0.98 9.2 2.3 2.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 PBP1_TM PF14812.6 GAM20184.1 - 9.6 6.7 13.0 0.16 12.4 3.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dynactin_p22 PF07426.11 GAM20185.1 - 3.2e-19 69.4 8.4 3.2e-19 69.4 8.4 2.4 1 1 1 3 3 3 1 Dynactin subunit p22 Holin_BhlA PF10960.8 GAM20185.1 - 0.0064 16.4 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 BhlA holin family VHP PF02209.19 GAM20186.1 - 3.2e-16 59.1 0.9 6.3e-16 58.1 0.9 1.5 1 0 0 1 1 1 1 Villin headpiece domain CRCB PF02537.15 GAM20187.1 - 2e-17 63.3 5.7 3.1e-17 62.7 5.7 1.2 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) GtrA PF04138.14 GAM20187.1 - 0.0016 18.7 3.6 0.34 11.2 0.0 2.2 1 1 1 2 2 2 2 GtrA-like protein Phage_holin_3_3 PF16083.5 GAM20187.1 - 0.011 15.8 1.7 0.011 15.8 1.7 2.5 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III Polysacc_synt_C PF14667.6 GAM20187.1 - 0.11 12.5 7.5 0.18 11.9 7.5 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain PrgI PF12666.7 GAM20187.1 - 4.6 8.0 7.9 9 7.1 2.7 2.4 1 1 0 2 2 2 0 PrgI family protein MIP PF00230.20 GAM20189.1 - 3e-46 157.9 16.6 1.7e-45 155.5 16.6 1.9 1 1 0 1 1 1 1 Major intrinsic protein YlaH PF14036.6 GAM20189.1 - 2.5 8.5 7.4 0.97 9.8 0.3 2.8 3 0 0 3 3 3 0 YlaH-like protein Peptidase_C1 PF00112.23 GAM20190.1 - 3.3e-74 249.7 12.6 6e-73 245.5 12.6 2.2 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM20190.1 - 9.5e-16 58.0 4.0 2.2e-15 56.8 4.0 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAM20190.1 - 0.00025 19.9 3.4 0.058 12.2 0.4 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Apt1 PF10351.9 GAM20190.1 - 0.46 9.3 9.6 0.64 8.8 9.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 GAM20190.1 - 1.1 9.1 10.9 1.5 8.6 10.9 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 GAM20190.1 - 6 5.3 14.5 8.1 4.9 14.5 1.2 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 GAM20190.1 - 8 5.5 19.9 11 5.1 19.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RRM_1 PF00076.22 GAM20191.1 - 0.011 15.6 0.1 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hamartin PF04388.12 GAM20191.1 - 2.3 6.8 16.4 2.6 6.6 16.4 1.2 1 0 0 1 1 1 0 Hamartin protein MAP65_ASE1 PF03999.12 GAM20191.1 - 7.5 5.1 18.7 5.1 5.7 16.4 1.7 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) Ank_2 PF12796.7 GAM20192.1 - 1.9e-05 25.1 0.9 6.3e-05 23.5 0.3 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM20192.1 - 0.00058 20.1 3.4 3 8.7 0.1 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 GAM20192.1 - 0.0051 17.4 2.2 3 8.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) ECH_2 PF16113.5 GAM20193.1 - 2.5e-79 267.2 0.0 3.9e-79 266.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAM20193.1 - 2e-18 66.6 0.0 4.9e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FERM_C PF09380.10 GAM20194.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 FERM C-terminal PH-like domain Nop14 PF04147.12 GAM20195.1 - 0.0069 14.7 1.3 0.026 12.7 0.0 2.3 2 0 0 2 2 2 1 Nop14-like family Init_tRNA_PT PF04179.12 GAM20195.1 - 0.039 14.2 0.4 0.46 10.8 0.4 2.9 2 0 0 2 2 2 0 Rit1 DUSP-like domain Spt20 PF12090.8 GAM20195.1 - 1.1 8.8 25.5 0.019 14.6 18.1 1.8 2 0 0 2 2 2 0 Spt20 family MMS1_N PF10433.9 GAM20196.1 - 7.9e-153 509.6 0.0 1.4e-152 508.8 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAM20196.1 - 8e-99 331.0 0.0 1.9e-97 326.5 0.0 2.7 3 0 0 3 3 3 1 CPSF A subunit region UQ_con PF00179.26 GAM20197.1 - 1.5e-19 70.0 0.1 1.8e-19 69.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme COX6B PF02297.17 GAM20198.1 - 0.059 13.6 1.5 0.5 10.6 0.2 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb PEN-2 PF10251.9 GAM20199.1 - 1.4e-23 83.1 9.1 1.8e-23 82.8 9.1 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DUF2207 PF09972.9 GAM20199.1 - 0.56 8.9 3.3 0.66 8.7 3.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPT6_acidic PF14632.6 GAM20200.1 - 0.0091 16.6 6.8 0.29 11.7 0.1 2.2 2 0 0 2 2 2 2 Acidic N-terminal SPT6 CarboxypepD_reg PF13620.6 GAM20201.1 - 0.0016 18.7 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 GAM20201.1 - 0.018 15.3 0.1 0.018 15.3 0.1 1.2 1 0 0 1 1 1 0 SdrD B-like domain DUF1604 PF07713.13 GAM20201.1 - 0.025 14.4 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) SdrD_B PF17210.3 GAM20202.1 - 3.9e-33 114.0 22.2 1.2e-12 48.1 1.6 5.2 5 0 0 5 5 5 5 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM20202.1 - 9e-10 38.7 1.6 0.76 10.1 0.1 5.4 5 0 0 5 5 5 2 Carboxypeptidase regulatory-like domain DUF1604 PF07713.13 GAM20202.1 - 0.0001 22.1 0.4 0.17 11.7 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1604) SpaA PF17802.1 GAM20202.1 - 0.027 14.8 15.1 0.47 10.8 1.8 5.3 4 2 0 4 4 4 0 Prealbumin-like fold domain fn3_3 PF14686.6 GAM20202.1 - 0.032 14.0 0.6 1.8 8.4 0.0 3.2 3 0 0 3 3 3 0 Polysaccharide lyase family 4, domain II Y_Y_Y PF07495.13 GAM20202.1 - 0.034 14.1 0.9 1 9.4 0.1 3.2 3 0 0 3 3 3 0 Y_Y_Y domain CHU_C PF13585.6 GAM20202.1 - 0.064 13.3 0.7 0.23 11.5 0.7 2.0 1 0 0 1 1 1 0 C-terminal domain of CHU protein family DUF2141 PF09912.9 GAM20202.1 - 0.09 12.7 1.3 19 5.2 0.0 4.6 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2141) GramPos_pilinD3 PF16570.5 GAM20202.1 - 0.35 11.6 3.0 3.2 8.5 0.1 2.9 3 0 0 3 3 3 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain Med15 PF09606.10 GAM20203.1 - 1.5e-05 24.0 47.7 1.5e-05 24.0 47.7 2.3 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal CDC45 PF02724.14 GAM20203.1 - 0.57 8.4 21.9 0.56 8.4 19.3 2.0 2 0 0 2 2 2 0 CDC45-like protein PAT1 PF09770.9 GAM20203.1 - 1.2 7.3 63.6 0.031 12.6 47.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Tim54 PF11711.8 GAM20203.1 - 1.4 7.6 31.9 0.02 13.7 20.2 2.7 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 V_ATPase_I PF01496.19 GAM20203.1 - 3.1 5.6 31.6 0.081 10.8 21.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family RGS PF00615.19 GAM20205.1 - 4.5e-06 26.9 1.3 0.081 13.2 0.1 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain PI-TkoII_IV PF18714.1 GAM20205.1 - 0.031 13.7 0.1 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV ESCRT-II PF05871.12 GAM20205.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 ESCRT-II complex subunit SET_assoc PF11767.8 GAM20205.1 - 0.14 11.9 0.3 0.36 10.5 0.1 1.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Macoilin PF09726.9 GAM20205.1 - 0.34 9.4 4.2 0.33 9.4 4.2 1.1 1 0 0 1 1 1 0 Macoilin family Mito_carr PF00153.27 GAM20206.1 - 3.7e-72 238.3 2.3 1.3e-28 98.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Guanylate_cyc PF00211.20 GAM20207.1 - 5.3e-76 254.3 2.8 6.5e-41 140.0 0.5 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 GAM20207.1 - 0.036 13.5 1.1 6.5 6.1 0.0 2.6 2 0 0 2 2 2 0 Heme NO binding associated AMP-binding PF00501.28 GAM20207.1 - 0.063 11.9 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme CDK2AP PF09806.9 GAM20207.1 - 9.8 6.2 9.4 0.42 10.6 2.9 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein PH PF00169.29 GAM20208.1 - 6.6e-10 39.4 0.6 3.2e-09 37.2 0.6 2.2 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 GAM20208.1 - 0.15 12.5 1.7 0.27 11.6 0.1 2.3 2 0 0 2 2 2 0 Plant pleckstrin homology-like region DUF573 PF04504.14 GAM20208.1 - 1.8 9.3 8.2 0.34 11.6 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function, DUF573 V_ATPase_I PF01496.19 GAM20208.1 - 4.1 5.2 16.3 0.95 7.3 12.4 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family XRN_M PF17846.1 GAM20208.1 - 4.2 6.2 11.7 0.65 8.9 7.2 1.9 2 1 0 2 2 2 0 Xrn1 helical domain Metallophos_2 PF12850.7 GAM20209.1 - 6e-23 81.8 0.2 6.9e-23 81.6 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TolA_bind_tri PF16331.5 GAM20209.1 - 0.12 12.5 0.1 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation PhoPQ_related PF10142.9 GAM20210.1 - 6.7e-62 209.3 0.1 8e-62 209.0 0.1 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein GTP_EFTU PF00009.27 GAM20211.1 - 2.6e-39 134.8 0.0 4.7e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM20211.1 - 3.9e-22 78.7 0.1 7.9e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAM20211.1 - 4.7e-10 39.7 0.1 1.4e-09 38.2 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM20211.1 - 6.1e-08 32.7 0.2 1.9e-06 28.0 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAM20211.1 - 0.0019 18.3 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 2 Dynamin family FeoB_N PF02421.18 GAM20211.1 - 0.013 15.0 0.5 0.81 9.2 0.1 3.0 2 1 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU_D4 PF14578.6 GAM20211.1 - 0.053 13.4 0.3 0.053 13.4 0.3 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AAA_29 PF13555.6 GAM20211.1 - 0.11 12.2 0.1 25 4.7 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM20211.1 - 0.2 11.5 0.8 14 5.6 0.0 3.0 1 1 1 2 2 2 0 RsgA GTPase NmrA PF05368.13 GAM20212.1 - 1.7e-29 103.0 0.1 2.3e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM20212.1 - 3.6e-07 30.3 0.0 5.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM20212.1 - 1e-05 24.7 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2487 PF10673.9 GAM20212.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Pox_polyA_pol PF03296.13 GAM20212.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain SOXp PF12336.8 GAM20212.1 - 0.13 13.4 0.0 3.8 8.6 0.0 2.7 3 0 0 3 3 3 0 SOX transcription factor CBS PF00571.28 GAM20214.1 - 5.1e-14 52.5 3.0 2.7e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 CBS domain DUF1487 PF07368.11 GAM20214.1 - 0.0024 17.3 0.2 0.0057 16.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) NCD1 PF04904.13 GAM20214.1 - 0.046 13.7 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) CBS PF00571.28 GAM20215.1 - 3.6e-05 24.1 0.0 6.9e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 CBS domain FNIP PF05725.12 GAM20216.1 - 3.9e-85 279.8 45.4 2.2e-14 53.3 0.0 11.9 9 2 4 14 14 14 12 FNIP Repeat DUF1769 PF08588.10 GAM20216.1 - 0.0041 17.3 8.0 6 7.1 0.0 6.3 6 2 1 7 7 7 1 Protein of unknown function (DUF1769) F-box-like PF12937.7 GAM20216.1 - 0.013 15.4 0.8 0.044 13.7 0.8 2.0 1 0 0 1 1 1 0 F-box-like AAT PF03417.16 GAM20217.1 - 0.079 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Tti2 PF10521.9 GAM20217.1 - 0.083 12.4 6.8 0.32 10.5 0.9 3.2 3 1 0 3 3 3 0 Tti2 family DUF5327 PF17261.2 GAM20217.1 - 0.11 13.2 1.7 1.8 9.3 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) UTP15_C PF09384.10 GAM20217.1 - 0.17 11.6 3.1 10 5.8 3.0 2.6 1 1 0 1 1 1 0 UTP15 C terminal FAST_2 PF08368.12 GAM20217.1 - 0.42 11.4 2.4 2.8 8.8 0.1 2.6 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 PH PF00169.29 GAM20218.1 - 5.9e-32 110.3 8.0 3.5e-17 62.8 1.0 2.9 3 0 0 3 3 3 2 PH domain LIM PF00412.22 GAM20218.1 - 2.3e-22 79.0 27.9 2.6e-10 40.4 8.2 3.5 3 0 0 3 3 3 3 LIM domain PH_11 PF15413.6 GAM20218.1 - 2.8e-10 40.6 16.7 5e-05 23.7 6.2 4.5 3 2 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 GAM20218.1 - 4e-08 33.6 1.8 0.0046 17.3 0.7 3.5 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 GAM20218.1 - 6.1e-05 23.2 2.2 7.6e-05 22.9 0.3 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 GAM20218.1 - 0.0011 19.1 0.9 0.0035 17.4 0.1 2.3 3 0 0 3 3 3 1 PH domain PH_13 PF16652.5 GAM20218.1 - 0.012 15.4 0.4 0.041 13.7 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_10 PF15411.6 GAM20218.1 - 0.87 9.9 3.5 1.5 9.1 0.3 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain NUDIX PF00293.28 GAM20219.1 - 1.4e-12 47.8 0.0 1.7e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain FEZ PF07763.13 GAM20219.1 - 0.023 14.5 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 FEZ-like protein Ras PF00071.22 GAM20220.1 - 1e-41 142.3 0.1 1.2e-41 142.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM20220.1 - 2.7e-30 105.1 0.1 3.9e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM20220.1 - 4.6e-13 49.0 0.1 6e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM20220.1 - 1.2e-06 28.1 0.0 4.1e-06 26.3 0.0 1.7 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM20220.1 - 1.8e-05 24.3 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM20220.1 - 0.00091 19.3 0.1 0.002 18.2 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM20220.1 - 0.0016 18.0 0.2 0.013 15.1 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 GAM20220.1 - 0.0053 16.6 0.2 0.017 14.9 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TniB PF05621.11 GAM20220.1 - 0.0058 16.1 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein MMR_HSR1_Xtn PF16897.5 GAM20220.1 - 0.0066 16.4 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_24 PF13479.6 GAM20220.1 - 0.058 13.1 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM20220.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NDUFA12 PF05071.16 GAM20221.1 - 1.5e-18 67.4 0.7 3.3e-18 66.3 0.7 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TPR_2 PF07719.17 GAM20222.1 - 3.2e-08 33.1 0.3 0.082 13.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM20222.1 - 5.2e-07 29.4 0.3 0.041 14.1 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM20222.1 - 9.8e-07 28.3 0.0 0.007 16.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM20222.1 - 8.1e-05 22.4 0.0 0.018 15.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM20222.1 - 0.0017 18.6 2.6 0.15 12.3 0.0 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM20222.1 - 0.0021 18.7 0.0 0.061 14.0 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM20222.1 - 0.034 14.5 0.0 7.3 7.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAM20222.1 - 0.035 14.3 0.7 0.12 12.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM20222.1 - 0.063 14.1 0.0 35 5.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TMEM154 PF15102.6 GAM20223.1 - 0.0017 18.3 0.7 0.0082 16.0 0.0 2.0 2 0 0 2 2 2 1 TMEM154 protein family Shisa PF13908.6 GAM20223.1 - 0.0022 18.3 1.9 0.0022 18.3 1.9 1.7 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator OAD_gamma PF04277.13 GAM20223.1 - 0.057 14.0 0.1 0.28 11.8 0.0 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF1382 PF07131.11 GAM20223.1 - 0.19 11.8 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) Mid2 PF04478.12 GAM20223.1 - 0.84 9.5 11.7 2.3 8.0 7.2 2.9 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor Sas6_CC PF18594.1 GAM20224.1 - 0.28 11.0 0.9 0.53 10.1 0.9 1.4 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain RRM_1 PF00076.22 GAM20225.1 - 2.6e-14 52.8 0.1 1.3e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM20225.1 - 0.0047 16.9 0.0 0.02 14.9 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NINJA_B PF16136.5 GAM20225.1 - 0.14 12.5 2.8 0.33 11.3 2.8 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal GpcrRhopsn4 PF10192.9 GAM20226.1 - 1.2e-09 37.9 13.4 1.2e-09 37.9 13.4 2.9 3 0 0 3 3 3 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 GAM20226.1 - 0.00023 20.5 29.5 0.00023 20.5 29.5 1.7 2 0 0 2 2 2 1 Lung seven transmembrane receptor Spermine_synth PF01564.17 GAM20227.1 - 1.8e-67 226.4 0.0 3.1e-67 225.7 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 GAM20227.1 - 2e-23 82.0 0.4 3.2e-23 81.4 0.4 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 GAM20227.1 - 0.00017 22.2 0.0 0.00042 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM20227.1 - 0.092 13.5 0.0 0.24 12.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain fn3 PF00041.21 GAM20228.1 - 1.6e-09 38.0 12.9 0.074 13.4 0.1 5.9 5 0 0 5 5 5 4 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 GAM20228.1 - 0.0003 21.3 1.7 0.0003 21.3 1.7 4.7 6 0 0 6 6 6 2 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 GAM20228.1 - 0.00045 20.5 0.9 3.4 8.0 0.0 4.2 3 0 0 3 3 3 2 Interferon-alpha/beta receptor, fibronectin type III Glyco_hydro_36C PF16874.5 GAM20228.1 - 0.002 18.6 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolase family 36 C-terminal domain EGF_Tenascin PF18720.1 GAM20228.1 - 0.0053 16.8 7.0 0.016 15.3 7.0 1.8 1 0 0 1 1 1 1 Tenascin EGF domain Arylsulfotran_N PF17425.2 GAM20228.1 - 0.0088 16.1 6.8 2.1 8.4 0.1 4.2 2 1 1 3 3 3 2 Arylsulfotransferase Ig-like domain EGF_2 PF07974.13 GAM20228.1 - 0.016 15.6 13.3 0.051 14.0 13.3 2.0 1 0 0 1 1 1 0 EGF-like domain Colipase-like PF15083.6 GAM20228.1 - 4.5 7.5 5.7 1.4 9.1 2.5 1.8 2 0 0 2 2 2 0 Colipase-like ISG65-75 PF11727.8 GAM20228.1 - 8.8 5.5 7.1 11 5.2 0.4 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein CRAL_TRIO PF00650.20 GAM20229.1 - 3.1e-28 98.5 0.6 4.2e-28 98.1 0.6 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAM20229.1 - 3.6e-07 30.4 0.3 8.6e-07 29.2 0.3 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain ABC1 PF03109.16 GAM20230.1 - 1.1e-35 122.4 0.9 2.4e-35 121.3 0.1 2.0 2 0 0 2 2 2 1 ABC1 family CCDC106 PF15794.5 GAM20230.1 - 0.051 13.3 3.8 0.085 12.6 3.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SprA-related PF12118.8 GAM20230.1 - 0.091 11.9 9.0 0.13 11.3 9.0 1.2 1 0 0 1 1 1 0 SprA-related family DUF863 PF05904.11 GAM20230.1 - 1.2 7.5 13.6 1.6 7.1 13.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) Urocanase PF01175.18 GAM20231.1 - 7.9e-87 290.3 0.0 1.2e-86 289.7 0.0 1.3 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 GAM20231.1 - 1.8e-84 282.1 2.0 2.7e-84 281.5 2.0 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase_N PF17391.2 GAM20231.1 - 8.7e-57 190.3 0.1 2e-56 189.2 0.1 1.6 1 0 0 1 1 1 1 Urocanase N-terminal domain bZIP_2 PF07716.15 GAM20232.1 - 1e-05 25.5 14.0 1e-05 25.5 14.0 5.2 4 2 2 6 6 6 1 Basic region leucine zipper bZIP_1 PF00170.21 GAM20232.1 - 1.4e-05 25.1 15.4 1.4e-05 25.1 15.4 2.9 3 0 0 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.17 GAM20232.1 - 0.011 16.2 7.0 0.011 16.2 7.0 7.1 5 2 2 7 7 7 0 bZIP Maf transcription factor ZapB PF06005.12 GAM20232.1 - 0.021 15.2 1.3 0.021 15.2 1.3 8.3 6 1 1 7 7 7 0 Cell division protein ZapB LRR_4 PF12799.7 GAM20233.1 - 6.5e-28 96.3 61.1 6.8e-09 35.9 1.0 5.5 1 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM20233.1 - 5.1e-19 67.8 28.7 5.2e-08 32.5 1.8 4.4 2 2 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 GAM20233.1 - 2.4e-07 30.4 26.4 1 10.2 0.8 8.4 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 GAM20233.1 - 9.7e-06 25.2 7.9 0.026 14.0 0.1 2.8 1 1 2 3 3 3 3 Leucine-rich repeat DUF2322 PF10084.9 GAM20233.1 - 0.05 13.6 0.1 8.9 6.4 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) LRRNT PF01462.18 GAM20233.1 - 0.34 10.6 3.0 16 5.3 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 GAM20233.1 - 0.41 10.8 31.4 5.5 7.3 0.2 8.1 8 0 0 8 8 8 0 Leucine Rich repeat GST_N_3 PF13417.6 GAM20234.1 - 1.7e-08 34.8 0.0 3.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM20234.1 - 1.1e-06 28.9 0.2 2.8e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM20234.1 - 1.7e-05 24.9 0.0 0.001 19.2 0.0 2.7 1 1 2 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM20234.1 - 3.4e-05 24.0 0.0 6.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAM20234.1 - 0.0038 17.0 0.0 0.015 15.1 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM20234.1 - 0.024 14.6 0.0 0.12 12.4 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAM20234.1 - 0.15 12.8 0.0 0.29 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain 7TM_transglut PF14402.6 GAM20235.1 - 0.0049 16.4 1.9 0.0069 15.9 1.9 1.2 1 0 0 1 1 1 1 7 transmembrane helices usually fused to an inactive transglutaminase Erf4 PF10256.9 GAM20235.1 - 0.023 14.8 1.6 0.049 13.7 1.6 1.6 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family Pkinase PF00069.25 GAM20236.1 - 1.5e-72 244.1 0.0 1.7e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20236.1 - 5.8e-27 94.6 0.0 7.6e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM20236.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M8 PF01457.16 GAM20237.1 - 9.4e-70 235.8 4.8 6.7e-69 233.0 4.8 1.9 1 1 0 1 1 1 1 Leishmanolysin Peptidase_C1 PF00112.23 GAM20238.1 - 5.7e-64 216.2 9.6 7.1e-64 215.9 9.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM20238.1 - 2.7e-13 50.1 0.6 5.5e-13 49.1 0.6 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAM20238.1 - 3.7e-05 22.7 0.1 0.19 10.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family NTPase_I-T PF01931.18 GAM20239.1 - 6e-47 159.5 0.0 7e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 DIE2_ALG10 PF04922.12 GAM20240.1 - 1.5e-111 373.5 34.0 2.3e-111 372.9 34.0 1.3 1 0 0 1 1 1 1 DIE2/ALG10 family REPA_OB_2 PF16900.5 GAM20240.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Replication protein A OB domain 2OG-FeII_Oxy_2 PF13532.6 GAM20241.1 - 1.1e-25 91.0 0.5 2e-25 90.1 0.5 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SR-25 PF10500.9 GAM20241.1 - 0.018 14.6 3.2 0.031 13.9 3.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mito_carr PF00153.27 GAM20242.1 - 2.6e-73 242.0 1.4 2.4e-24 85.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SSXT PF05030.12 GAM20243.1 - 3.5e-15 55.4 3.9 3.5e-15 55.4 3.9 2.5 1 1 1 2 2 2 1 SSXT protein (N-terminal region) Glyco_transf_92 PF01697.27 GAM20243.1 - 0.0029 17.3 0.6 0.0029 17.3 0.6 2.7 2 1 1 3 3 3 1 Glycosyltransferase family 92 DFP PF04127.15 GAM20243.1 - 0.21 11.4 1.7 0.42 10.4 1.7 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein YmaF PF12788.7 GAM20244.1 - 0.0024 18.4 0.4 0.0034 17.9 0.4 1.2 1 0 0 1 1 1 1 YmaF family DUF4380 PF14315.6 GAM20244.1 - 0.13 11.2 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) 4F5 PF04419.14 GAM20245.1 - 3.8e-05 24.5 4.7 3.8e-05 24.5 4.7 2.3 2 1 0 2 2 2 1 4F5 protein family Macoilin PF09726.9 GAM20245.1 - 1.1 7.8 8.0 0.97 7.9 8.0 1.1 1 0 0 1 1 1 0 Macoilin family FNIP PF05725.12 GAM20246.1 - 1.5e-06 28.2 6.5 8.8e-05 22.6 0.1 4.4 4 1 0 4 4 4 2 FNIP Repeat CH PF00307.31 GAM20247.1 - 1.1e-16 61.0 0.0 3.1e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM20247.1 - 0.0044 16.8 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Peptidase_S10 PF00450.22 GAM20248.1 - 3.5e-106 356.1 9.4 4.2e-106 355.9 9.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Sdh_cyt PF01127.22 GAM20248.1 - 0.14 12.2 1.4 0.9 9.6 0.2 2.3 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit UBA PF00627.31 GAM20250.1 - 1.2e-18 66.6 5.5 3.4e-11 42.8 0.2 3.2 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 GAM20250.1 - 2.6e-18 65.5 11.5 6.6e-18 64.2 10.3 2.1 2 0 0 2 2 2 1 XPC-binding domain ubiquitin PF00240.23 GAM20250.1 - 5.7e-16 58.0 0.5 9.5e-16 57.3 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM20250.1 - 2.2e-06 27.4 0.3 4.5e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Propep_M14 PF02244.16 GAM20250.1 - 0.0022 18.3 0.8 0.24 11.8 0.1 2.9 2 0 0 2 2 2 1 Carboxypeptidase activation peptide MCM_N PF14551.6 GAM20250.1 - 0.0028 18.2 1.8 0.0029 18.2 0.2 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Sigma70_ner PF04546.13 GAM20250.1 - 0.0053 16.7 0.0 0.0086 16.0 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region GlnE PF03710.15 GAM20250.1 - 0.043 13.2 0.2 0.07 12.5 0.2 1.2 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase DnaB_2 PF07261.11 GAM20250.1 - 0.09 12.5 0.0 0.45 10.3 0.1 2.2 3 0 0 3 3 3 0 Replication initiation and membrane attachment Rad60-SLD_2 PF13881.6 GAM20250.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HTH_38 PF13936.6 GAM20250.1 - 0.17 11.6 0.2 0.46 10.3 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain CD52 PF15116.6 GAM20250.1 - 1.6 8.8 0.0 1.6 8.8 0.0 2.5 2 1 0 2 2 1 0 CAMPATH-1 antigen EF_TS PF00889.19 GAM20251.1 - 4.9e-39 134.1 0.0 6.9e-37 127.1 0.0 2.4 1 1 0 1 1 1 1 Elongation factor TS UBA PF00627.31 GAM20251.1 - 0.0017 18.3 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TPR_12 PF13424.6 GAM20252.1 - 2.1e-23 82.4 6.3 2.7e-09 37.2 0.0 5.2 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM20252.1 - 1e-08 34.9 0.5 0.0004 19.9 0.0 3.5 1 1 1 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 GAM20252.1 - 4.9e-08 33.1 4.5 2.4 9.2 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM20252.1 - 1.2e-06 28.9 7.9 0.011 16.2 0.6 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAM20252.1 - 4e-06 26.5 3.1 0.47 10.4 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM20252.1 - 5.9e-05 22.7 6.6 1.8 8.5 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM20252.1 - 0.00016 21.6 6.4 5.2 7.6 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM20252.1 - 0.00037 20.7 0.9 0.067 13.6 0.3 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM20252.1 - 0.00085 19.3 11.4 13 6.1 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM20252.1 - 0.042 14.1 2.7 7.4 6.9 1.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TFCD_C PF12612.8 GAM20252.1 - 0.054 13.3 0.8 1.5 8.6 0.1 2.6 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal TPR_16 PF13432.6 GAM20252.1 - 0.28 11.9 3.7 43 4.9 0.1 4.6 4 2 1 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 GAM20253.1 - 7.5e-31 105.8 0.1 2.9e-16 59.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM20253.1 - 0.0013 18.5 0.0 0.39 10.6 0.0 2.8 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 GAM20253.1 - 0.0067 16.5 0.1 0.23 11.6 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif Spo7_2_N PF15407.6 GAM20253.1 - 0.11 12.2 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein family 7 RNA_lig_T4_1 PF09511.10 GAM20255.1 - 5.5e-40 137.6 0.2 9.5e-40 136.8 0.2 1.3 1 0 0 1 1 1 1 RNA ligase HmuY PF14064.6 GAM20255.1 - 0.016 15.4 0.0 0.045 14.0 0.0 1.8 1 1 0 1 1 1 0 HmuY protein DUF366 PF04017.12 GAM20255.1 - 0.049 13.1 0.2 0.97 8.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF366) Ribosomal_L29 PF00831.23 GAM20256.1 - 3.4e-14 52.5 2.3 3.4e-14 52.5 2.3 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein YgaB PF14182.6 GAM20256.1 - 0.013 15.8 2.9 0.15 12.4 0.6 2.5 2 1 0 2 2 2 0 YgaB-like protein Nup54_57_C PF18570.1 GAM20256.1 - 0.03 13.9 2.7 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Snapin_Pallidin PF14712.6 GAM20256.1 - 0.089 13.2 5.6 0.36 11.3 1.8 2.2 1 1 1 2 2 2 0 Snapin/Pallidin CBS PF00571.28 GAM20257.1 - 8.8e-14 51.7 7.0 5.2e-05 23.6 0.4 4.4 4 0 0 4 4 4 3 CBS domain Nop10p PF04135.12 GAM20258.1 - 5.6e-20 71.1 0.8 6.5e-20 70.9 0.8 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ank_2 PF12796.7 GAM20259.1 - 1.1e-28 99.6 6.3 7.4e-11 42.5 1.3 5.0 1 1 5 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20259.1 - 5.1e-26 90.7 9.3 1.1e-06 29.1 0.1 7.3 4 4 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20259.1 - 7.7e-20 70.7 12.5 0.007 16.7 0.4 9.0 4 2 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20259.1 - 1.5e-17 61.9 8.4 0.25 12.0 0.0 9.6 6 1 4 10 10 10 5 Ankyrin repeat Ank PF00023.30 GAM20259.1 - 4.9e-08 33.1 2.5 1.4 9.4 0.0 6.8 2 2 1 3 3 3 2 Ankyrin repeat P16-Arc PF04699.14 GAM20260.1 - 1.4e-37 129.5 0.1 1.5e-37 129.4 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 GAM20260.1 - 0.0047 17.2 0.0 0.009 16.3 0.0 1.4 2 0 0 2 2 2 1 Dip2/Utp12 Family Utp13 PF08625.11 GAM20260.1 - 0.018 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain E2F_TDP PF02319.20 GAM20261.1 - 9.4e-28 96.1 1.0 5.4e-13 48.8 0.1 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 GAM20261.1 - 0.019 14.8 0.3 0.6 10.0 0.1 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Cdc6_C PF09079.11 GAM20261.1 - 0.039 13.9 0.0 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DnaJ PF00226.31 GAM20262.1 - 4.4e-24 84.4 1.6 4.4e-24 84.4 1.6 2.5 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 GAM20262.1 - 6.5e-08 32.7 4.5 6.5e-08 32.7 4.5 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 GAM20262.1 - 1.1e-05 25.8 6.6 0.075 13.9 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM20262.1 - 5.5e-05 23.4 11.0 0.056 13.9 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 GAM20262.1 - 0.00013 22.2 2.8 0.00013 22.2 2.8 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAM20262.1 - 0.0019 18.5 16.4 0.016 15.5 0.3 3.6 3 1 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 GAM20262.1 - 0.26 11.4 9.6 1 9.5 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger MIP PF00230.20 GAM20263.1 - 2e-49 168.4 20.0 5.9e-33 114.5 9.0 2.0 2 0 0 2 2 2 2 Major intrinsic protein PalH PF08733.10 GAM20263.1 - 0.051 12.6 0.3 0.074 12.0 0.3 1.2 1 0 0 1 1 1 0 PalH/RIM21 CLTH PF10607.9 GAM20264.1 - 9.2e-37 126.2 1.3 1.3e-36 125.7 1.3 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GAM20264.1 - 1.4e-10 40.8 1.0 3.1e-10 39.6 0.3 2.0 2 0 0 2 2 2 1 LisH TINF2_N PF14973.6 GAM20264.1 - 0.0085 16.5 3.9 0.051 13.9 0.1 2.8 1 1 2 3 3 3 1 TERF1-interacting nuclear factor 2 N-terminus Cas_St_Csn2 PF16813.5 GAM20264.1 - 0.026 13.6 0.9 0.036 13.2 0.9 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St UvrD-helicase PF00580.21 GAM20264.1 - 0.27 10.7 3.6 0.42 10.1 3.6 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain VHP PF02209.19 GAM20265.1 - 4.8e-13 48.9 2.7 2.1e-12 46.9 2.7 2.2 1 0 0 1 1 1 1 Villin headpiece domain UPF0203 PF05254.12 GAM20266.1 - 2.3e-16 59.8 8.8 2.8e-16 59.5 8.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CX9C PF16860.5 GAM20266.1 - 0.0011 18.9 3.5 0.0079 16.2 0.3 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 GAM20266.1 - 0.0013 19.0 1.8 0.0013 19.0 1.8 1.7 2 1 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) DUF4125 PF13526.6 GAM20266.1 - 0.0084 15.7 0.6 0.0091 15.6 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4125) Cmc1 PF08583.10 GAM20266.1 - 0.14 12.2 6.5 2.1 8.4 0.3 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 GAM20266.1 - 0.96 9.9 8.3 2.2 8.7 8.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Pkinase_Tyr PF07714.17 GAM20267.1 - 3.8e-69 232.8 0.0 4.8e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM20267.1 - 3.3e-60 203.7 0.0 4.8e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kelch_3 PF13415.6 GAM20267.1 - 1.1e-26 92.5 6.0 1.2e-07 31.8 0.0 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM20267.1 - 6.3e-25 86.9 12.2 3.3e-08 33.4 0.1 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM20267.1 - 1.8e-24 85.2 0.5 0.00018 21.4 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 GAM20267.1 - 8.1e-20 70.2 5.4 1.5e-05 24.5 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 GAM20267.1 - 6.2e-19 67.2 14.4 4.6e-07 29.5 0.1 6.4 7 0 0 7 7 6 4 Kelch motif Kelch_6 PF13964.6 GAM20267.1 - 6e-18 64.4 9.7 6e-05 23.2 0.0 6.3 5 1 1 6 6 6 4 Kelch motif Pkinase_fungal PF17667.1 GAM20267.1 - 0.00031 19.6 0.5 0.00055 18.8 0.5 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM20267.1 - 0.0032 16.5 0.9 0.045 12.7 0.9 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM20267.1 - 0.0065 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM20267.1 - 0.029 13.7 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Orthopox_C10L PF07020.11 GAM20268.1 - 0.015 16.1 5.0 0.015 16.1 5.0 2.8 3 0 0 3 3 3 0 Orthopoxvirus C10L protein F-protein PF00469.20 GAM20268.1 - 2 8.0 3.9 0.69 9.5 0.5 1.8 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Sds3 PF08598.11 GAM20269.1 - 5.8e-18 65.7 20.8 5.8e-18 65.7 20.8 4.8 3 3 1 4 4 4 1 Sds3-like Me-amine-dh_L PF02975.14 GAM20269.1 - 0.17 12.4 1.4 0.56 10.7 1.4 1.9 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Lipoprotein_3 PF00938.17 GAM20269.1 - 1.7 8.9 8.6 1.3 9.3 1.6 3.5 2 1 1 3 3 3 0 Lipoprotein Homeodomain PF00046.29 GAM20270.1 - 1.4e-19 69.7 4.6 2.5e-19 68.8 4.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAM20270.1 - 0.0046 16.8 0.2 0.009 15.9 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain tRNA-synt_1g PF09334.11 GAM20271.1 - 1.6e-150 501.2 0.1 2.1e-150 500.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 GAM20271.1 - 7.4e-20 70.9 0.7 1.3e-19 70.0 0.7 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 GAM20271.1 - 6.2e-08 31.3 1.9 0.0084 14.4 0.3 3.3 3 1 1 4 4 4 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM20271.1 - 1.4e-07 31.6 0.1 2.5e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA COG6 PF06419.11 GAM20271.1 - 0.12 10.6 1.1 0.47 8.6 0.1 2.4 3 0 0 3 3 3 0 Conserved oligomeric complex COG6 zinc-ribbons_6 PF07191.12 GAM20271.1 - 0.25 11.3 3.2 0.57 10.2 3.2 1.6 1 0 0 1 1 1 0 zinc-ribbons Alpha_L_fucos PF01120.17 GAM20272.1 - 1.4e-120 403.0 3.0 1.7e-120 402.7 3.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 GAM20272.1 - 3.5e-16 59.5 0.4 6.4e-16 58.7 0.4 1.4 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Arf PF00025.21 GAM20273.1 - 1.5e-48 164.5 0.0 1.8e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GAM20273.1 - 4.7e-14 52.3 1.5 1.6e-10 40.7 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 GAM20273.1 - 1e-10 41.8 0.0 1.9e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM20273.1 - 5e-09 36.0 0.0 6.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAM20273.1 - 5.5e-09 35.7 0.0 7.1e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM20273.1 - 6.4e-09 35.5 0.0 7.4e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM20273.1 - 2.7e-05 24.2 0.0 4.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM20273.1 - 6.1e-05 23.5 0.0 0.00013 22.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM20273.1 - 0.00014 21.9 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAM20273.1 - 0.00019 21.1 0.4 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 GAM20273.1 - 0.00047 20.4 0.6 0.0097 16.2 0.6 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 GAM20273.1 - 0.0024 18.4 0.1 0.0032 18.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 GAM20273.1 - 0.0026 17.4 1.0 0.53 9.8 0.2 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 GAM20273.1 - 0.0058 17.2 0.0 0.016 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 GAM20273.1 - 0.0097 15.8 1.2 0.2 11.6 1.2 2.4 1 1 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 GAM20273.1 - 0.0099 16.4 0.8 0.014 15.9 0.7 1.6 1 1 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 GAM20273.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 GAM20273.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_29 PF13555.6 GAM20273.1 - 0.038 13.7 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.6 GAM20273.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 GAM20273.1 - 0.13 11.2 0.2 16 4.4 0.0 2.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 GAM20273.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 GAM20273.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ACOX PF01756.19 GAM20274.1 - 3.3e-11 43.1 0.0 6.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 GAM20274.1 - 9.6e-10 38.5 0.0 1.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAM20274.1 - 2.7e-06 27.7 0.0 5.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 GAM20274.1 - 0.0051 17.4 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal G-alpha PF00503.20 GAM20275.1 - 1.3e-109 366.7 5.6 1.5e-109 366.4 5.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM20275.1 - 1.4e-14 54.0 0.6 7e-11 41.9 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM20275.1 - 0.003 17.0 1.1 0.93 8.8 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM20275.1 - 0.0071 16.6 0.4 3.1 8.0 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAM20275.1 - 0.025 14.7 0.0 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF2985 PF11204.8 GAM20275.1 - 0.05 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) AAA_29 PF13555.6 GAM20275.1 - 0.053 13.3 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cnn_1N PF07989.11 GAM20276.1 - 8.2e-08 32.3 5.3 8.2e-08 32.3 5.3 10.3 6 3 3 9 9 9 2 Centrosomin N-terminal motif 1 SET PF00856.28 GAM20277.1 - 3e-15 57.0 1.1 3e-15 57.0 1.1 2.6 2 2 0 2 2 2 1 SET domain TPR_2 PF07719.17 GAM20277.1 - 0.0024 17.9 0.2 5.1 7.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM20277.1 - 0.0039 17.4 1.6 0.76 10.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM20277.1 - 0.026 14.4 0.0 0.026 14.4 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM20277.1 - 0.034 14.7 0.2 0.23 12.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MUG113 PF13455.6 GAM20277.1 - 0.25 12.0 1.7 16 6.2 0.3 3.5 2 1 0 2 2 2 0 Meiotically up-regulated gene 113 tRNA-synt_1b PF00579.25 GAM20278.1 - 1.5e-69 234.6 0.5 2e-69 234.1 0.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribonuc_2-5A PF06479.12 GAM20278.1 - 0.0052 17.0 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease 2-5A DUF4942 PF13708.6 GAM20278.1 - 0.039 13.9 0.1 0.062 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) NIF PF03031.18 GAM20279.1 - 4.7e-54 182.4 0.4 1.1e-53 181.2 0.4 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Synaptobrevin PF00957.21 GAM20280.1 - 8.4e-27 92.8 5.8 9.7e-27 92.6 5.8 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF1676 PF07898.13 GAM20280.1 - 0.0012 18.9 1.3 0.0013 18.8 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) RIFIN PF02009.16 GAM20280.1 - 0.0063 16.4 2.1 0.0065 16.4 2.1 1.0 1 0 0 1 1 1 1 Rifin Orf78 PF06024.12 GAM20280.1 - 0.0089 16.3 3.0 0.0089 16.3 3.0 1.8 1 1 1 2 2 2 1 Orf78 (ac78) Sec5 PF15469.6 GAM20280.1 - 0.057 13.2 3.4 0.069 13.0 3.4 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF3560 PF12083.8 GAM20280.1 - 0.065 13.4 0.2 0.084 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Ferlin_C PF16165.5 GAM20280.1 - 0.086 12.8 4.6 0.052 13.5 2.9 1.4 1 1 1 2 2 2 0 Ferlin C-terminus UPF0258 PF06789.12 GAM20280.1 - 0.21 11.7 3.5 0.31 11.2 3.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF5383 PF17355.2 GAM20280.1 - 0.6 10.5 4.2 0.75 10.2 4.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5383) Acyltransferase PF01553.21 GAM20281.1 - 1.5e-16 60.2 0.0 2.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase PROCT PF08084.11 GAM20281.1 - 0.024 14.6 0.1 0.8 9.6 0.0 2.7 3 0 0 3 3 3 0 PROCT (NUC072) domain Rad51 PF08423.11 GAM20282.1 - 1.2e-05 24.7 0.1 5.3e-05 22.6 0.1 1.8 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GAM20282.1 - 0.00025 20.7 0.0 0.0006 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 GAM20282.1 - 0.0016 17.9 0.0 0.0085 15.6 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase_2 PF01637.18 GAM20282.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 GAM20282.1 - 0.054 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 GAM20282.1 - 0.087 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Androgen_recep PF02166.16 GAM20282.1 - 1.1 8.1 6.1 1.7 7.4 6.1 1.3 1 0 0 1 1 1 0 Androgen receptor PA14 PF07691.12 GAM20283.1 - 0.0047 16.7 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain LysE PF01810.18 GAM20283.1 - 0.21 11.0 0.7 0.3 10.5 0.7 1.1 1 0 0 1 1 1 0 LysE type translocator FNIP PF05725.12 GAM20284.1 - 2.1e-46 155.8 34.2 2e-13 50.3 0.1 7.5 4 1 5 9 9 9 9 FNIP Repeat FNIP PF05725.12 GAM20285.1 - 1.1e-42 143.9 22.7 4.6e-12 45.9 0.8 7.3 6 1 1 7 7 7 6 FNIP Repeat Glyco_hydro_85 PF03644.13 GAM20286.1 - 5.3e-87 292.0 1.3 6.8e-87 291.7 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 FBA PF04300.13 GAM20286.1 - 2.2e-14 53.6 0.0 4.3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 F-box associated region Glyco_hydro_18 PF00704.28 GAM20286.1 - 0.011 15.5 0.1 0.16 11.7 0.1 2.1 1 1 0 1 1 1 0 Glycosyl hydrolases family 18 FNIP PF05725.12 GAM20287.1 - 1.1e-66 220.7 42.7 5e-13 49.0 2.8 7.3 5 1 1 7 7 7 7 FNIP Repeat DUF1769 PF08588.10 GAM20287.1 - 0.0054 16.9 3.4 11 6.3 0.0 4.4 2 2 3 5 5 5 2 Protein of unknown function (DUF1769) EamA PF00892.20 GAM20288.1 - 0.00026 21.2 13.6 0.0047 17.1 13.6 2.1 1 1 0 1 1 1 1 EamA-like transporter family Thia_YuaJ PF09515.10 GAM20288.1 - 0.0033 17.4 5.5 0.0056 16.7 5.4 1.4 1 1 0 1 1 1 1 Thiamine transporter protein (Thia_YuaJ) PgaD PF13994.6 GAM20288.1 - 0.0034 17.4 0.7 0.71 9.9 0.2 2.2 2 0 0 2 2 2 2 PgaD-like protein DUF543 PF04418.12 GAM20288.1 - 0.018 15.0 1.4 0.15 12.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF543) TMEM234 PF10639.9 GAM20288.1 - 0.025 14.6 3.1 0.13 12.3 3.1 2.1 1 1 0 1 1 1 0 Putative transmembrane family 234 DUF4064 PF13273.6 GAM20288.1 - 0.099 12.9 8.7 1.7 9.0 8.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Ribosomal_S6e PF01092.19 GAM20289.1 - 6.3e-53 178.0 0.0 1.1e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Sybindin PF04099.12 GAM20290.1 - 1.2e-47 161.4 0.4 1.4e-47 161.2 0.4 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 GAM20290.1 - 6.6e-08 32.7 0.1 7.7e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region GTP_EFTU PF00009.27 GAM20291.1 - 2.6e-32 111.9 0.1 2.6e-32 111.9 0.1 2.7 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAM20291.1 - 3.7e-14 52.7 0.7 1.5e-13 50.7 0.7 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 GAM20291.1 - 1.3e-08 35.1 9.5 1.3e-08 35.1 0.3 3.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM20291.1 - 5.3e-08 32.9 0.0 3.2e-07 30.4 0.0 2.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GAM20291.1 - 2.5e-07 30.5 0.1 7.6e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 GAM20291.1 - 0.00037 20.7 0.2 0.0027 17.9 0.0 2.6 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 GAM20291.1 - 0.0004 20.3 0.1 0.0023 17.8 0.1 2.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 GAM20291.1 - 0.02 14.8 4.9 0.14 12.0 2.2 3.3 2 1 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 GAM20291.1 - 0.021 14.4 0.2 0.13 11.8 0.2 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 GAM20291.1 - 0.032 14.5 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAM20291.1 - 7.4 7.0 0.0 7.4 7.0 0.0 4.8 4 1 1 5 5 3 0 AAA domain Coiled PF05710.12 GAM20292.1 - 0.013 16.3 0.4 0.013 16.3 0.4 2.0 1 1 1 2 2 2 0 Coiled coil rve_2 PF13333.6 GAM20292.1 - 0.15 12.3 3.0 0.17 12.1 2.7 1.3 1 1 0 1 1 1 0 Integrase core domain GTP_EFTU PF00009.27 GAM20293.1 - 1.2e-44 152.2 0.0 2e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 GAM20293.1 - 2.4e-27 96.0 8.8 4.6e-27 95.0 8.8 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 GAM20293.1 - 8.8e-22 77.2 0.0 1.7e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 GAM20293.1 - 6.2e-21 74.2 0.0 1.3e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAM20293.1 - 1.7e-08 34.7 0.1 3.6e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAM20293.1 - 1.2e-07 31.7 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAM20293.1 - 0.0006 19.9 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 GAM20293.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Septin Roc PF08477.13 GAM20293.1 - 0.016 15.4 0.0 0.12 12.6 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 GAM20293.1 - 0.11 12.1 0.0 0.46 10.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Actin PF00022.19 GAM20294.1 - 2.7e-152 507.1 0.0 8.6e-152 505.5 0.0 1.6 1 1 0 1 1 1 1 Actin CWC25 PF12542.8 GAM20296.1 - 2.6e-12 47.5 2.8 2.6e-12 47.5 2.8 4.6 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 GAM20296.1 - 1e-10 41.6 11.1 1e-10 41.6 11.1 5.6 5 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Josephin PF02099.17 GAM20296.1 - 0.0082 16.3 0.0 0.05 13.7 0.0 2.5 2 1 0 2 2 2 1 Josephin CTP_transf_like PF01467.26 GAM20297.1 - 0.033 14.4 0.6 0.3 11.3 0.1 2.7 2 0 0 2 2 2 0 Cytidylyltransferase-like Fmp27_SW PF10305.9 GAM20297.1 - 6.4 7.5 6.8 1.6 9.5 0.5 3.2 3 1 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain PRK PF00485.18 GAM20298.1 - 4.3e-24 85.4 1.1 2.8e-23 82.7 1.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.21 GAM20298.1 - 5.1e-07 29.8 0.0 9.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 CYTH domain AAA_33 PF13671.6 GAM20298.1 - 0.00019 21.6 0.2 0.00071 19.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAM20298.1 - 0.00066 18.9 0.1 0.0016 17.7 0.1 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.6 GAM20298.1 - 0.0026 17.5 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM20298.1 - 0.0027 18.2 0.0 0.012 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 GAM20298.1 - 0.01 15.7 0.1 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 GAM20298.1 - 0.015 15.7 0.0 0.49 10.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 GAM20298.1 - 0.046 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 GAM20298.1 - 0.057 13.3 0.4 0.49 10.3 0.2 2.3 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 GAM20298.1 - 0.058 13.3 2.1 0.17 11.7 0.0 2.5 3 0 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 GAM20298.1 - 0.089 13.3 1.5 0.21 12.1 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 GAM20298.1 - 0.097 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 GAM20298.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SUIM_assoc PF16619.5 GAM20298.1 - 0.17 11.9 7.4 0.51 10.4 7.4 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 BESS PF02944.20 GAM20299.1 - 0.14 12.0 4.7 1 9.3 0.1 2.5 2 0 0 2 2 2 0 BESS motif DUF3439 PF11921.8 GAM20299.1 - 0.27 11.2 7.9 3.8 7.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAM20299.1 - 1.9 8.4 19.7 0.91 9.5 5.6 3.0 3 0 0 3 3 3 0 Mucin-like glycoprotein PH PF00169.29 GAM20300.1 - 3e-17 63.0 0.4 5.1e-17 62.3 0.4 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM20300.1 - 2.4e-05 24.5 0.1 3.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAM20300.1 - 0.00031 21.1 3.1 0.018 15.5 3.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 GAM20300.1 - 0.0089 16.4 0.1 0.019 15.3 0.1 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain 7tm_1 PF00001.21 GAM20301.1 - 0.00019 20.8 14.8 0.00019 20.8 14.8 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 GAM20301.1 - 3.7 7.7 8.6 0.51 10.4 1.8 2.8 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term SdrD_B PF17210.3 GAM20302.1 - 1.1e-36 125.5 4.4 5.2e-09 36.3 0.0 4.4 4 0 0 4 4 4 4 SdrD B-like domain SpaA PF17802.1 GAM20302.1 - 0.00031 21.0 0.0 0.088 13.2 0.1 3.2 3 0 0 3 3 3 1 Prealbumin-like fold domain DUF1416 PF07210.12 GAM20302.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) DUF2012 PF09430.10 GAM20302.1 - 0.068 13.3 0.0 9.4 6.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2012) PRCC PF10253.9 GAM20302.1 - 0.43 11.4 5.5 0.72 10.6 5.5 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 GAM20302.1 - 0.49 9.5 12.7 0.6 9.3 12.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Drf_FH1 PF06346.12 GAM20302.1 - 1.1 9.0 20.1 1.9 8.2 20.1 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 Lactonase PF10282.9 GAM20303.1 - 1e-98 330.8 0.0 1.2e-98 330.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 GAM20303.1 - 8.4e-05 22.3 0.0 2.8 7.5 0.0 4.5 2 2 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 GAM20303.1 - 0.0015 18.6 0.0 9.7 6.5 0.0 3.9 4 0 0 4 4 4 1 Arylesterase SBBP PF06739.11 GAM20303.1 - 0.068 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Beta-propeller repeat Myotub-related PF06602.14 GAM20304.1 - 3.4e-134 447.2 0.0 3.4e-134 447.2 0.0 1.8 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain GRAM PF02893.20 GAM20304.1 - 0.0021 17.9 0.9 0.0075 16.1 0.1 2.3 2 0 0 2 2 2 1 GRAM domain Y_phosphatase PF00102.27 GAM20304.1 - 0.013 15.0 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAM20304.1 - 0.031 14.3 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Mod_r PF07200.13 GAM20304.1 - 1.4 9.1 25.0 2 8.5 5.4 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein zf-C3HC4_3 PF13920.6 GAM20304.1 - 2.3 8.1 7.9 11 6.0 5.6 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2318 PF10080.9 GAM20304.1 - 2.4 8.3 6.6 1.7 8.8 2.9 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) LIM PF00412.22 GAM20304.1 - 3 8.1 10.5 2 8.7 1.4 2.8 2 0 0 2 2 2 0 LIM domain ADIP PF11559.8 GAM20304.1 - 6.7 6.8 27.5 0.45 10.6 13.0 3.1 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Thg1 PF04446.12 GAM20305.1 - 4.9e-34 117.1 0.1 6.3e-34 116.7 0.1 1.1 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Oxysterol_BP PF01237.18 GAM20306.1 - 1.5e-49 168.8 14.5 4e-44 151.0 3.6 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DMAP_binding PF06464.11 GAM20306.1 - 0.036 14.9 0.0 0.092 13.6 0.0 1.7 1 0 0 1 1 1 0 DMAP1-binding Domain POT1 PF02765.17 GAM20306.1 - 0.043 13.6 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 UPF0565 PF10561.9 GAM20306.1 - 0.057 12.6 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 APG6_N PF17675.1 GAM20306.1 - 2.2 8.8 4.6 0.59 10.7 0.8 1.9 2 1 0 2 2 2 0 Apg6 coiled-coil region Proteasome PF00227.26 GAM20308.1 - 2.4e-23 82.6 0.1 4.4e-23 81.8 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Ribosomal_L29 PF00831.23 GAM20309.1 - 0.096 12.7 2.5 0.17 11.9 0.2 2.5 2 1 1 3 3 3 0 Ribosomal L29 protein tRNA-synt_1f PF01921.18 GAM20310.1 - 0.11 11.4 1.1 0.13 11.1 1.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) RAI1 PF08652.11 GAM20311.1 - 5.7e-20 71.3 0.2 1.3e-19 70.1 0.2 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease MINDY_DUB PF04424.13 GAM20312.1 - 6.7e-28 97.1 0.0 1.3e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase Hormone_3 PF00159.18 GAM20312.1 - 3 8.0 4.9 1.3 9.2 1.7 2.0 2 0 0 2 2 2 0 Pancreatic hormone peptide NTF2 PF02136.20 GAM20313.1 - 6.2e-20 72.0 0.3 7.4e-20 71.7 0.3 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DAP_epimerase PF01678.19 GAM20314.1 - 7.9e-47 158.4 0.1 2.9e-25 88.8 0.0 2.5 2 1 0 2 2 2 2 Diaminopimelate epimerase MEA1 PF06910.11 GAM20315.1 - 0.00032 21.3 0.4 0.00032 21.3 0.4 2.4 1 1 0 2 2 2 1 Male enhanced antigen 1 (MEA1) Sld5 PF05916.11 GAM20315.1 - 4.2 7.9 5.3 20 5.7 5.3 2.0 1 1 0 1 1 1 0 GINS complex protein Actin PF00022.19 GAM20316.1 - 4.2e-87 292.4 0.0 3.3e-56 190.7 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 GAM20316.1 - 0.11 11.3 0.0 6.1 5.6 0.0 2.3 2 1 0 2 2 2 0 MreB/Mbl protein PH_3 PF14593.6 GAM20316.1 - 0.16 12.1 0.3 12 6.1 0.0 2.3 2 0 0 2 2 2 0 PH domain MgrB PF13998.6 GAM20317.1 - 2.3 8.1 4.5 32 4.5 0.2 2.6 2 0 0 2 2 2 0 MgrB protein GTP_EFTU PF00009.27 GAM20318.1 - 4.7e-46 156.8 0.1 1.5e-45 155.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM20318.1 - 4.3e-26 91.4 0.0 1.1e-25 90.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 GAM20318.1 - 6.6e-07 29.4 0.0 0.00043 20.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase HBS1_N PF08938.10 GAM20318.1 - 5.1e-05 23.5 7.2 0.00011 22.4 7.2 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.25 GAM20318.1 - 0.0014 19.0 0.3 0.0032 17.8 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 GAM20318.1 - 0.0024 17.7 0.5 0.0054 16.6 0.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 T2SSE PF00437.20 GAM20318.1 - 0.025 13.7 0.3 0.043 12.9 0.3 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1296 PF06972.11 GAM20318.1 - 0.077 13.1 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) AAA_16 PF13191.6 GAM20318.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RP-C_C PF11800.8 GAM20318.1 - 4.1 7.4 12.5 0.074 13.1 1.7 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region C2 PF00168.30 GAM20319.1 - 1.4e-13 51.1 0.3 1.3e-11 44.7 0.1 2.3 2 0 0 2 2 2 1 C2 domain WW PF00397.26 GAM20319.1 - 3.4e-12 46.2 1.3 6.6e-12 45.3 1.3 1.5 1 0 0 1 1 1 1 WW domain TFIIA PF03153.13 GAM20319.1 - 0.45 10.5 15.5 0.61 10.0 15.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRCC PF10253.9 GAM20319.1 - 7.1 7.4 12.4 13 6.5 12.4 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Coiled PF05710.12 GAM20320.1 - 1.3e-17 64.4 8.1 1.5e-17 64.2 8.1 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 GAM20321.1 - 6.6e-18 65.3 7.6 8e-18 65.1 7.6 1.1 1 0 0 1 1 1 1 Coiled coil ATP-synt_DE_N PF02823.16 GAM20322.1 - 8.3e-17 60.9 0.0 1.2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain CLASP_N PF12348.8 GAM20323.1 - 8.6e-21 74.5 26.9 4e-07 29.8 1.5 7.3 6 1 1 7 7 7 4 CLASP N terminal HEAT PF02985.22 GAM20323.1 - 2.5e-15 55.2 24.1 0.0019 18.3 0.8 11.0 12 0 0 12 12 11 4 HEAT repeat HEAT_2 PF13646.6 GAM20323.1 - 9.4e-09 35.5 8.7 3.8 8.0 0.2 9.8 9 1 0 10 10 10 2 HEAT repeats Cnd1 PF12717.7 GAM20323.1 - 4.3e-05 23.6 30.6 0.24 11.4 0.2 9.3 7 3 3 11 11 11 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAM20323.1 - 6.4e-05 23.4 8.9 0.31 11.6 0.2 7.3 8 0 0 8 8 8 1 HEAT-like repeat UME PF08064.13 GAM20323.1 - 9.6e-05 22.2 1.5 0.0047 16.8 0.0 4.4 4 0 0 4 4 4 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 GAM20323.1 - 0.00026 21.5 14.9 7 7.3 0.0 9.9 11 3 4 15 15 13 1 Vacuolar 14 Fab1-binding region TAN PF11640.8 GAM20323.1 - 0.0004 20.5 10.2 5.9 7.0 0.1 7.0 6 0 0 6 6 6 2 Telomere-length maintenance and DNA damage repair LON_substr_bdg PF02190.16 GAM20323.1 - 0.0062 16.4 1.9 0.026 14.4 0.0 3.2 3 1 0 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain HrpB1_HrpK PF09613.10 GAM20323.1 - 0.025 14.2 1.0 18 5.0 0.0 4.4 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TIP120 PF08623.10 GAM20323.1 - 0.044 13.6 8.5 1.4 8.7 0.1 5.2 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Cadherin_3 PF16184.5 GAM20323.1 - 0.061 13.3 0.4 2.4 8.2 0.0 3.2 3 0 0 3 3 3 0 Cadherin-like WRW PF10206.9 GAM20323.1 - 0.11 12.8 0.1 0.39 11.1 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f HATPase_c PF02518.26 GAM20324.1 - 1.8e-24 86.4 0.0 6.8e-24 84.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM20324.1 - 6.1e-20 71.5 0.0 1.5e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAM20324.1 - 4.3e-12 45.9 0.0 8.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 GAM20324.1 - 9.1e-06 25.6 0.0 2.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 PAS domain Borrelia_orfX PF04160.12 GAM20324.1 - 0.0068 16.5 6.6 0.017 15.2 6.6 1.6 1 0 0 1 1 1 1 Orf-X protein PAS_9 PF13426.7 GAM20324.1 - 0.0075 16.5 1.0 0.073 13.3 0.3 2.8 3 0 0 3 3 3 1 PAS domain Ank_2 PF12796.7 GAM20325.1 - 6.5e-21 74.7 3.3 1.8e-05 25.2 0.0 4.2 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20325.1 - 3.9e-19 68.7 3.7 3.5e-07 30.6 0.1 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20325.1 - 4e-17 62.1 6.0 0.00014 22.0 0.1 6.8 4 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20325.1 - 5e-15 54.1 1.8 1.7 9.5 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 GAM20325.1 - 3.4e-05 24.1 4.7 74 4.0 0.0 6.8 4 2 2 6 6 6 0 Ankyrin repeat DUF3447 PF11929.8 GAM20325.1 - 0.016 15.1 0.0 0.25 11.4 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) GTP1_OBG PF01018.22 GAM20326.1 - 1.8e-47 160.8 5.0 4.1e-33 114.2 3.4 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 GAM20326.1 - 9.4e-20 70.8 0.0 2.9e-19 69.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM20326.1 - 2.8e-05 23.7 0.0 0.00071 19.1 0.0 2.8 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 GAM20326.1 - 0.042 14.4 0.0 1.4 9.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain Dynein_light PF01221.18 GAM20327.1 - 8.3e-32 109.4 4.0 8.8e-32 109.3 4.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 MMgT PF10270.9 GAM20328.1 - 7.1e-15 55.2 0.1 9.1e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter DUF2905 PF11146.8 GAM20328.1 - 0.051 13.8 0.1 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2905) RRM_1 PF00076.22 GAM20329.1 - 1.2e-20 73.1 0.0 6e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hid1 PF12722.7 GAM20329.1 - 7.4 4.6 6.8 9.3 4.2 6.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TPR_1 PF00515.28 GAM20330.1 - 1.4e-16 59.5 0.4 1e-06 28.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM20330.1 - 3.4e-14 51.7 0.7 0.0013 18.7 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM20330.1 - 2.7e-07 30.3 1.4 0.013 15.7 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM20330.1 - 3e-06 27.4 2.4 0.0018 18.5 0.3 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM20330.1 - 7.9e-06 25.5 0.8 1.8 8.8 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM20330.1 - 0.00012 21.6 3.1 0.54 10.0 0.0 3.5 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 GAM20330.1 - 0.0011 19.6 0.3 0.22 12.4 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM20330.1 - 0.0019 18.0 1.5 0.79 9.7 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM20330.1 - 0.0019 18.8 1.6 0.59 10.8 0.5 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM20330.1 - 0.0054 17.3 1.1 0.86 10.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 GAM20330.1 - 0.086 13.3 0.3 2.4 8.6 0.0 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_19 PF14559.6 GAM20330.1 - 0.099 13.2 0.2 2.4 8.7 0.3 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 GAM20330.1 - 0.12 12.5 3.7 0.73 9.9 0.0 3.2 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain Proteasome PF00227.26 GAM20331.1 - 3.2e-51 173.5 0.8 3.8e-51 173.3 0.8 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 GAM20331.1 - 1.7e-05 24.2 2.5 2.3e-05 23.7 0.1 2.3 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Glucosamine_iso PF01182.20 GAM20332.1 - 6.3e-19 68.7 0.0 1.3e-12 48.1 0.0 2.2 2 0 0 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PIG-L PF02585.17 GAM20332.1 - 1.3e-17 64.7 0.0 3.1e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SBP PF03110.14 GAM20332.1 - 0.17 12.3 0.0 27 5.2 0.0 3.2 2 1 1 3 3 3 0 SBP domain TMEM239 PF15841.5 GAM20333.1 - 5.3 6.9 7.6 1.3 8.9 3.7 1.9 2 0 0 2 2 2 0 Transmembrane protein 239 family Fig1 PF12351.8 GAM20333.1 - 9.9 6.0 13.0 7.6 6.4 9.3 2.4 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Amastin PF07344.11 GAM20334.1 - 0.016 15.1 8.4 0.031 14.1 7.7 1.8 1 1 0 1 1 1 0 Amastin surface glycoprotein RDD PF06271.12 GAM20334.1 - 0.037 14.2 4.5 0.071 13.3 4.5 1.4 1 0 0 1 1 1 0 RDD family DUF2207 PF09972.9 GAM20334.1 - 0.04 12.7 0.6 0.048 12.4 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Endomucin PF07010.12 GAM20334.1 - 0.057 13.4 0.1 1.1 9.2 0.1 2.0 2 0 0 2 2 2 0 Endomucin DUF3792 PF12670.7 GAM20334.1 - 0.075 13.2 6.8 0.088 13.0 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DUF1190 PF06693.11 GAM20334.1 - 0.18 12.2 0.0 0.29 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) PepSY_TM_like_2 PF16357.5 GAM20334.1 - 0.55 10.2 5.8 0.92 9.4 5.8 1.4 1 0 0 1 1 1 0 Putative PepSY_TM-like DHHC PF01529.20 GAM20334.1 - 0.72 10.0 6.1 1.6 8.8 6.1 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase TMEM43 PF07787.12 GAM20334.1 - 0.83 9.0 2.7 1.3 8.4 2.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 DUF3985 PF13153.6 GAM20334.1 - 5.8 7.0 11.3 0.14 12.2 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3985) HMG_box PF00505.19 GAM20335.1 - 2.4e-18 66.3 1.8 2.4e-18 66.3 1.8 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAM20335.1 - 1.7e-12 47.7 1.1 1.7e-12 47.7 1.1 1.7 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 GAM20335.1 - 0.0032 17.4 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 CHDNT (NUC034) domain SR-25 PF10500.9 GAM20335.1 - 0.57 9.8 19.4 1.4 8.5 10.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein YABBY PF04690.13 GAM20335.1 - 4.3 7.9 9.3 0.61 10.6 4.9 1.7 1 1 1 2 2 2 0 YABBY protein PNP_phzG_C PF10590.9 GAM20336.1 - 0.022 14.8 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region DUF2207 PF09972.9 GAM20336.1 - 7.9 5.1 6.4 2.4 6.8 3.7 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RRM_1 PF00076.22 GAM20338.1 - 1.6e-35 120.7 1.2 1.7e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM20338.1 - 3.4e-07 30.3 0.2 0.0039 17.3 0.0 2.8 2 2 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 GAM20338.1 - 9.5e-07 28.5 0.0 4.5e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM20338.1 - 0.0012 18.7 0.0 0.059 13.2 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 GAM20338.1 - 0.0012 19.1 0.2 14 5.9 0.0 3.3 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter Dicty_REP PF05086.12 GAM20338.1 - 0.0052 14.9 5.3 0.0066 14.5 5.3 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein DUF4944 PF16302.5 GAM20338.1 - 0.025 14.6 0.0 0.69 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4944) DbpA PF03880.15 GAM20338.1 - 0.026 14.5 0.1 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain Med3 PF11593.8 GAM20338.1 - 7 5.7 13.2 10 5.2 13.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PseudoU_synth_1 PF01416.20 GAM20339.1 - 1.8e-08 34.8 0.0 2.9e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase RPA43_OB PF17875.1 GAM20339.1 - 0.13 12.9 2.6 7.6 7.2 0.3 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Thiolase_N PF00108.23 GAM20340.1 - 4.8e-87 291.6 0.2 8.3e-87 290.8 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM20340.1 - 8.8e-44 148.1 0.2 1.6e-43 147.3 0.2 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAM20340.1 - 0.00024 20.8 0.1 0.00061 19.4 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 GAM20340.1 - 0.12 12.6 0.1 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Histone_H2A_C PF16211.5 GAM20341.1 - 3.2e-12 46.0 0.3 3.2e-12 46.0 0.3 2.0 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 GAM20341.1 - 1.3e-08 35.3 0.1 2.2e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAM20341.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Methyltransf_11 PF08241.12 GAM20342.1 - 2e-23 82.9 0.1 1.5e-22 80.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM20342.1 - 3.3e-21 75.8 0.1 1.8e-20 73.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM20342.1 - 3.6e-21 75.5 0.1 1.3e-20 73.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM20342.1 - 1.5e-18 67.2 0.0 4.9e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM20342.1 - 1.6e-15 57.0 0.0 7.3e-15 54.9 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAM20342.1 - 6.1e-13 49.4 0.1 7.2e-12 45.9 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain CMAS PF02353.20 GAM20342.1 - 9.7e-13 48.0 0.1 3e-12 46.4 0.0 1.8 3 0 0 3 3 3 1 Mycolic acid cyclopropane synthetase Polyketide_cyc2 PF10604.9 GAM20342.1 - 9.7e-08 32.4 0.1 3.2e-07 30.7 0.1 1.8 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 GAM20342.1 - 7.9e-05 22.4 0.1 0.00014 21.7 0.1 1.4 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) MetW PF07021.12 GAM20342.1 - 0.00016 21.3 0.1 0.00051 19.7 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.10 GAM20342.1 - 0.00025 20.6 0.0 0.0007 19.2 0.0 1.8 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DOT1 PF08123.13 GAM20342.1 - 0.00044 19.8 0.7 0.0039 16.7 0.0 2.4 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 GAM20342.1 - 0.00075 19.5 0.1 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAM20342.1 - 0.0011 18.5 0.0 0.0033 17.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 GAM20342.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 GAM20342.1 - 0.003 17.4 0.0 0.017 14.9 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 GAM20342.1 - 0.0086 15.6 0.0 0.082 12.4 0.0 2.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 GAM20342.1 - 0.021 14.1 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Polyketide_cyc PF03364.20 GAM20342.1 - 0.04 14.1 0.1 0.11 12.7 0.1 1.8 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport UPF0020 PF01170.18 GAM20342.1 - 0.079 12.6 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 PPV_E2_C PF00511.17 GAM20342.1 - 0.12 12.6 4.7 1.7 8.9 0.2 3.3 2 1 1 3 3 3 0 E2 (early) protein, C terminal Endosulfine PF04667.17 GAM20343.1 - 0.00017 21.7 0.0 0.00017 21.6 0.0 1.3 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF4038 PF13204.6 GAM20343.1 - 0.18 11.4 0.0 0.19 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) S1 PF00575.23 GAM20344.1 - 1.6e-15 57.2 10.2 1.4e-06 28.6 0.0 7.1 6 2 0 6 6 6 3 S1 RNA binding domain AvrPto PF11592.8 GAM20344.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto Nop14 PF04147.12 GAM20344.1 - 4.3 5.4 47.2 0.26 9.5 20.2 2.1 2 0 0 2 2 2 0 Nop14-like family DUF1129 PF06570.11 GAM20345.1 - 0.0086 15.6 2.6 0.0086 15.6 2.6 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) TraQ PF09679.10 GAM20345.1 - 0.047 13.6 1.3 0.078 12.9 0.0 2.0 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Reticulon PF02453.17 GAM20345.1 - 0.09 12.7 0.3 0.09 12.7 0.3 3.5 2 2 1 3 3 3 0 Reticulon DUF3810 PF12725.7 GAM20345.1 - 0.2 10.9 2.4 0.61 9.4 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) TPR_2 PF07719.17 GAM20346.1 - 6.8e-05 22.7 3.1 0.23 11.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM20346.1 - 0.00024 20.8 6.2 0.81 9.6 0.0 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM20346.1 - 0.00028 20.9 0.1 0.00059 19.8 0.1 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 GAM20346.1 - 0.0062 17.3 1.2 0.012 16.4 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM20346.1 - 0.013 15.7 1.7 0.027 14.7 1.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAM20346.1 - 0.031 14.8 1.8 0.16 12.5 1.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM20346.1 - 0.072 13.2 0.7 15 5.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 GAM20346.1 - 0.16 12.1 4.0 6.3 6.9 0.2 2.9 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 GAM20346.1 - 0.29 10.9 3.0 1.4 8.6 0.1 3.1 4 0 0 4 4 4 0 TPR repeat NAP PF00956.18 GAM20347.1 - 2.9e-06 26.7 8.6 6.4e-06 25.5 8.6 1.7 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) AOX PF01786.17 GAM20348.1 - 2.7e-76 255.9 0.5 3.7e-76 255.5 0.5 1.2 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 GAM20348.1 - 0.0014 18.4 0.0 0.004 17.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 AKAP7_NLS PF10469.9 GAM20349.1 - 4.5e-29 101.8 0.0 5.9e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 GAM20349.1 - 5.2e-05 23.2 0.0 7.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 GAM20349.1 - 0.0044 17.2 0.0 1.7 8.9 0.0 2.8 2 1 0 2 2 2 2 LigT like Phosphoesterase MOSC_N PF03476.16 GAM20350.1 - 2e-31 108.4 0.0 5.6e-31 106.9 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 GAM20350.1 - 1.2e-28 99.7 0.0 1.8e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 MOSC domain FYVE PF01363.21 GAM20354.1 - 6.9e-20 71.0 11.6 1.2e-19 70.2 11.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 GAM20354.1 - 3e-11 43.8 0.4 6.8e-11 42.6 0.4 1.6 1 0 0 1 1 1 1 PH domain Pro-MCH PF05824.12 GAM20354.1 - 0.0035 17.2 0.2 0.092 12.7 0.1 2.5 2 0 0 2 2 2 1 Pro-melanin-concentrating hormone (Pro-MCH) FYVE_2 PF02318.16 GAM20354.1 - 0.0065 16.7 6.5 0.012 15.8 6.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger PH_11 PF15413.6 GAM20354.1 - 0.064 13.7 0.7 0.32 11.4 0.7 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain RhoGEF PF00621.20 GAM20355.1 - 5.1e-50 170.2 2.4 7.5e-50 169.7 2.4 1.2 1 0 0 1 1 1 1 RhoGEF domain DUF4108 PF13390.6 GAM20355.1 - 0.025 14.5 6.8 0.044 13.7 3.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4108) 14-3-3 PF00244.20 GAM20355.1 - 0.051 13.1 4.7 0.39 10.2 4.5 2.3 1 1 0 1 1 1 0 14-3-3 protein UBN_AB PF14075.6 GAM20355.1 - 0.056 13.2 1.7 0.26 11.0 0.1 2.1 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Fez1 PF06818.15 GAM20356.1 - 0.0003 21.3 2.3 0.0003 21.3 2.3 1.5 2 0 0 2 2 2 1 Fez1 Csm1_N PF18504.1 GAM20356.1 - 0.00046 20.5 9.0 0.0012 19.1 9.0 1.7 1 0 0 1 1 1 1 Csm1 N-terminal domain Tup_N PF08581.10 GAM20356.1 - 0.0024 18.2 9.4 0.0046 17.2 9.4 1.5 1 0 0 1 1 1 1 Tup N-terminal DUF1635 PF07795.11 GAM20356.1 - 0.011 15.6 3.0 0.011 15.6 3.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1635) MPS2 PF17060.5 GAM20356.1 - 0.013 14.8 3.9 0.022 14.1 3.9 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF724 PF05266.14 GAM20356.1 - 0.051 13.4 2.3 0.099 12.5 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APG6_N PF17675.1 GAM20356.1 - 0.053 14.0 7.5 0.089 13.3 7.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_1 PF00170.21 GAM20356.1 - 0.054 13.6 1.7 0.054 13.6 1.7 2.3 1 1 1 2 2 2 0 bZIP transcription factor HMMR_N PF15905.5 GAM20356.1 - 0.06 12.8 6.3 0.12 11.9 6.3 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal bZIP_2 PF07716.15 GAM20356.1 - 0.087 12.9 0.3 0.087 12.9 0.3 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Urocanase PF01175.18 GAM20356.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain PhoU PF01895.19 GAM20356.1 - 0.11 13.0 1.4 0.25 11.8 1.4 1.6 1 0 0 1 1 1 0 PhoU domain Histone_HNS PF00816.21 GAM20356.1 - 0.16 12.8 0.6 0.36 11.7 0.2 1.9 1 1 1 2 2 2 0 H-NS histone family DUF641 PF04859.12 GAM20356.1 - 0.54 10.6 6.9 0.25 11.7 3.8 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 GAM20356.1 - 0.68 9.1 2.1 1.1 8.4 2.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein PKcGMP_CC PF16808.5 GAM20356.1 - 0.89 9.5 10.8 0.81 9.6 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase OmpH PF03938.14 GAM20356.1 - 1.5 9.2 7.7 2.4 8.5 7.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Abhydro_lipase PF04083.16 GAM20357.1 - 6.5e-16 57.7 2.5 9.7e-16 57.1 0.1 2.4 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.7 GAM20357.1 - 0.00062 20.4 0.0 0.00096 19.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM20357.1 - 0.0027 17.4 0.9 0.0027 17.4 0.9 2.9 2 2 0 2 2 2 1 alpha/beta hydrolase fold Macoilin PF09726.9 GAM20357.1 - 0.004 15.8 6.6 0.0058 15.3 6.6 1.2 1 0 0 1 1 1 1 Macoilin family TFIIA PF03153.13 GAM20357.1 - 0.077 13.0 25.3 0.11 12.4 25.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 GAM20357.1 - 0.92 9.1 28.0 2.2 7.8 28.0 1.7 1 0 0 1 1 1 0 Spt20 family GET2 PF08690.10 GAM20357.1 - 5.6 6.5 20.7 4.9 6.7 19.2 1.6 1 1 0 1 1 1 0 GET complex subunit GET2 DUF647 PF04884.14 GAM20358.1 - 9.3e-80 267.7 2.9 1.2e-79 267.4 2.9 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis BURP PF03181.15 GAM20358.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 BURP domain DUF3128 PF11326.8 GAM20359.1 - 5.8e-14 52.2 0.1 5.8e-14 52.2 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3128) Peptidase_S15 PF02129.18 GAM20359.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FNIP PF05725.12 GAM20360.1 - 1.8e-71 236.0 35.3 5.5e-12 45.6 4.6 10.9 6 2 5 12 12 12 11 FNIP Repeat RNA_pol_L_2 PF13656.6 GAM20361.1 - 2.4e-29 100.9 0.3 3.8e-29 100.3 0.1 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 GAM20361.1 - 1.7e-13 49.8 0.0 2.9e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TGT PF01702.18 GAM20362.1 - 6.9e-141 469.4 0.0 9e-141 469.1 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DEAD PF00270.29 GAM20363.1 - 1.1e-43 149.1 0.2 1.5e-43 148.6 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM20363.1 - 4.7e-28 97.8 1.8 3.6e-27 94.9 0.7 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM20363.1 - 1.5e-05 25.0 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FNIP PF05725.12 GAM20364.1 - 6.9e-63 208.6 24.7 5.8e-11 42.4 0.3 9.5 3 1 5 10 10 10 10 FNIP Repeat FNIP PF05725.12 GAM20365.1 - 3.8e-97 318.3 43.7 2.5e-12 46.8 0.5 11.3 4 3 11 15 15 15 14 FNIP Repeat F-box PF00646.33 GAM20365.1 - 0.0046 16.8 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM20365.1 - 0.0061 16.4 1.2 0.074 13.0 0.1 2.7 2 0 0 2 2 2 1 F-box-like SQS_PSY PF00494.19 GAM20366.1 - 1.2e-45 156.0 0.4 1.5e-45 155.7 0.4 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase RNA_pol_A_bac PF01000.26 GAM20367.1 - 3e-34 117.7 0.0 5.6e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAM20367.1 - 2e-11 43.1 0.0 2.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ABC_membrane_2 PF06472.15 GAM20368.1 - 3.2e-49 167.7 5.2 5.3e-49 167.1 5.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAM20368.1 - 1.5e-15 57.9 0.0 3.6e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Adeno_IVa2 PF02456.15 GAM20368.1 - 0.0033 16.3 0.5 0.085 11.6 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_16 PF13191.6 GAM20368.1 - 0.0036 17.7 0.0 0.0077 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 GAM20368.1 - 0.0098 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 GAM20368.1 - 0.0098 15.6 0.1 0.028 14.1 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GAM20368.1 - 0.021 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 GAM20368.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 GAM20368.1 - 0.03 14.2 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Sigma54_activat PF00158.26 GAM20368.1 - 0.037 13.7 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 GAM20368.1 - 0.081 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAM20368.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TMEM171 PF15471.6 GAM20368.1 - 0.11 11.5 0.2 0.18 10.8 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Cytidylate_kin PF02224.18 GAM20368.1 - 0.11 12.2 0.1 17 5.1 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_23 PF13476.6 GAM20368.1 - 0.13 12.8 0.1 0.45 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAM20368.1 - 0.16 12.0 0.1 0.51 10.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Translin PF01997.16 GAM20369.1 - 4e-47 160.9 0.7 4.7e-47 160.6 0.7 1.0 1 0 0 1 1 1 1 Translin family Ribosomal_L7Ae PF01248.26 GAM20370.1 - 2.1e-22 78.7 0.0 2.5e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GST_C_3 PF14497.6 GAM20371.1 - 2.8e-23 82.0 0.2 5e-23 81.2 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM20371.1 - 1.3e-08 35.1 0.0 3.6e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM20371.1 - 1.3e-07 31.8 0.1 1.8e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM20371.1 - 0.00015 21.7 0.4 0.00045 20.2 0.2 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM20371.1 - 0.00023 21.5 0.0 0.00043 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 GAM20371.1 - 0.0049 17.6 0.0 0.0093 16.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GAM20371.1 - 0.058 13.2 0.1 0.15 11.8 0.1 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain WH2 PF02205.20 GAM20372.1 - 2.6e-10 39.8 1.3 4.7e-10 39.0 1.3 1.4 1 0 0 1 1 1 1 WH2 motif zf-RING_2 PF13639.6 GAM20373.1 - 8.8e-05 22.8 9.9 8.8e-05 22.8 9.9 9.1 6 3 2 8 8 8 2 Ring finger domain Sgf11 PF08209.11 GAM20373.1 - 0.00047 19.7 0.4 0.00047 19.7 0.4 4.9 6 0 0 6 6 6 1 Sgf11 (transcriptional regulation protein) zf-RING_UBOX PF13445.6 GAM20373.1 - 0.0059 16.6 3.8 0.0059 16.6 3.8 6.6 6 2 0 6 6 6 2 RING-type zinc-finger Med13_C PF06333.12 GAM20373.1 - 0.31 10.3 9.1 0.5 9.6 9.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Sporozoite_P67 PF05642.11 GAM20373.1 - 0.92 7.5 9.3 1.9 6.5 9.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 GAM20373.1 - 1.2 9.1 33.3 3 7.9 33.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein MAGE_N PF12440.8 GAM20373.1 - 4.5 8.0 8.8 0.1 13.3 1.9 1.8 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Patched PF02460.18 GAM20374.1 - 2.5e-94 317.0 6.2 2.5e-94 317.0 6.2 2.5 2 1 1 3 3 3 2 Patched family Sterol-sensing PF12349.8 GAM20374.1 - 1.9e-49 167.4 8.5 1.9e-49 167.4 8.5 3.7 4 0 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 GAM20374.1 - 3.8e-20 72.5 13.6 7.3e-20 71.6 11.8 2.3 2 1 0 2 2 2 1 Niemann-Pick C1 N terminus ACR_tran PF00873.19 GAM20374.1 - 0.85 7.2 18.6 1.4 6.5 18.6 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family RRM_1 PF00076.22 GAM20375.1 - 5.2e-45 151.1 0.1 6.4e-20 70.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM20375.1 - 1.1e-07 31.4 0.1 0.014 14.9 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAM20375.1 - 0.00081 19.4 0.0 2.6 8.2 0.0 2.9 3 0 0 3 3 3 2 Limkain b1 Nup35_RRM_2 PF14605.6 GAM20375.1 - 0.0009 19.2 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAM20375.1 - 0.04 14.0 0.0 7.7 6.7 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif RL PF17797.1 GAM20375.1 - 0.043 13.8 0.3 0.46 10.5 0.0 2.5 2 0 0 2 2 2 0 RL domain RRM_3 PF08777.11 GAM20375.1 - 0.053 13.6 0.0 17 5.5 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif 3H PF02829.14 GAM20375.1 - 0.08 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 3H domain CENP-B_dimeris PF09026.10 GAM20376.1 - 0.0069 16.8 6.9 0.0069 16.8 6.9 3.1 3 0 0 3 3 3 1 Centromere protein B dimerisation domain TMF_DNA_bd PF12329.8 GAM20376.1 - 0.013 15.4 0.4 0.013 15.4 0.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fungal_TACC PF12709.7 GAM20376.1 - 0.028 14.9 0.9 0.028 14.9 0.9 2.0 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins CCDC92 PF14916.6 GAM20376.1 - 0.054 13.3 1.9 0.14 11.9 1.9 1.8 1 1 0 1 1 1 0 Coiled-coil domain of unknown function HMMR_N PF15905.5 GAM20376.1 - 1.2 8.5 12.4 0.081 12.4 2.7 2.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SOG2 PF10428.9 GAM20376.1 - 4.5 6.4 23.3 0.36 10.0 17.3 1.9 2 0 0 2 2 2 0 RAM signalling pathway protein BTV_NS2 PF04514.12 GAM20376.1 - 5 5.9 11.1 8.5 5.1 11.1 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1676 PF07898.13 GAM20376.1 - 7.2 6.6 10.3 0.57 10.2 4.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1676) Dynein_IC2 PF11540.8 GAM20377.1 - 1.1e-11 44.4 0.9 4e-11 42.6 0.9 2.0 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 GAM20377.1 - 7e-10 39.3 17.2 0.0023 18.7 0.6 6.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM20377.1 - 0.025 14.8 0.0 0.59 10.5 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 GAM20377.1 - 0.1 12.3 0.9 15 5.2 0.3 3.2 2 2 1 3 3 3 0 TUP1-like enhancer of split HEAT PF02985.22 GAM20378.1 - 5.3e-13 48.0 18.8 0.08 13.2 0.1 10.3 11 0 0 11 11 9 3 HEAT repeat Cnd1 PF12717.7 GAM20378.1 - 3.5e-11 43.4 13.2 5.7e-07 29.7 0.4 5.1 4 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAM20378.1 - 1.6e-09 38.0 4.8 0.0025 18.3 0.1 7.1 6 1 1 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAM20378.1 - 1.9e-09 38.0 2.2 0.004 17.7 0.1 6.2 4 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 GAM20378.1 - 3.2e-07 30.2 4.1 3.3e-06 26.9 1.7 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 GAM20378.1 - 6.4e-07 29.7 0.0 0.22 12.0 0.0 6.4 7 3 2 9 9 8 2 HEAT repeats CLASP_N PF12348.8 GAM20378.1 - 1.9e-05 24.4 2.9 0.54 9.8 0.0 5.0 3 1 3 6 6 6 2 CLASP N terminal Adaptin_N PF01602.20 GAM20378.1 - 2.3e-05 23.2 9.5 0.00017 20.3 0.3 4.5 2 1 2 4 4 4 1 Adaptin N terminal region DUF3385 PF11865.8 GAM20378.1 - 6e-05 23.0 2.6 0.032 14.2 0.0 4.9 4 2 2 7 7 7 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 GAM20378.1 - 6.5e-05 22.7 3.4 0.29 10.9 0.0 4.7 4 1 0 4 4 4 2 rRNA processing/ribosome biogenesis CENP-B_dimeris PF09026.10 GAM20378.1 - 0.00058 20.2 4.2 0.00058 20.2 4.2 2.6 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Importin_rep_4 PF18808.1 GAM20378.1 - 0.00083 19.6 0.0 0.00083 19.6 0.0 4.5 5 0 0 5 5 4 1 Importin repeat DUF4042 PF13251.6 GAM20378.1 - 0.011 15.4 0.4 1.8 8.2 0.0 4.2 6 0 0 6 6 5 0 Domain of unknown function (DUF4042) RTP1_C1 PF10363.9 GAM20378.1 - 0.012 15.8 0.2 3.2 8.0 0.0 4.0 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 GAM20378.1 - 0.027 14.5 2.5 47 4.2 0.0 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.8 GAM20378.1 - 0.1 13.2 0.5 1.6 9.4 0.0 3.1 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation FAM176 PF14851.6 GAM20378.1 - 1.4 8.5 4.8 3.7 7.2 0.5 2.3 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 GAM20378.1 - 7.8 6.5 8.5 14 5.7 2.0 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Ras PF00071.22 GAM20379.1 - 5.8e-53 178.8 0.0 6.8e-53 178.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM20379.1 - 4.2e-19 68.9 0.1 8.5e-19 67.9 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM20379.1 - 2.1e-08 33.8 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAM20379.1 - 0.0001 22.2 0.0 0.0065 16.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM20379.1 - 0.0012 18.9 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Serglycin PF04360.12 GAM20380.1 - 0.0013 18.7 5.3 0.0029 17.6 5.3 1.6 1 0 0 1 1 1 1 Serglycin Lin-8 PF03353.15 GAM20380.1 - 7.3 6.1 10.6 11 5.5 10.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Putative_PNPOx PF01243.20 GAM20381.1 - 1.2e-15 57.5 0.1 2.2e-08 34.2 0.0 2.8 4 0 0 4 4 4 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 GAM20381.1 - 5.7e-08 33.4 0.0 1.7e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAM20381.1 - 1.8e-07 31.4 0.0 5.1e-07 29.9 0.0 1.7 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 GAM20381.1 - 1.7e-06 28.3 0.0 7.3e-05 23.1 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain DEAD PF00270.29 GAM20382.1 - 9.2e-37 126.5 0.0 1.6e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM20382.1 - 1e-29 103.1 0.3 4.6e-27 94.6 0.2 3.0 2 1 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAM20382.1 - 1.1e-05 25.4 0.1 3.4e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAM20382.1 - 0.00094 18.6 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RCC1 PF00415.18 GAM20383.1 - 6.2e-72 238.1 16.6 2.1e-14 53.9 1.0 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM20383.1 - 8.1e-40 133.9 25.1 1.8e-07 30.8 0.0 8.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RasGAP PF00616.19 GAM20383.1 - 1.3e-35 123.1 10.5 1.5e-33 116.3 0.0 3.7 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RhoGEF PF00621.20 GAM20383.1 - 1.4e-21 77.6 3.3 1.4e-21 77.6 3.3 2.3 2 1 0 2 2 2 1 RhoGEF domain BAR_3 PF16746.5 GAM20383.1 - 1.2e-07 31.7 8.6 1.2e-07 31.7 8.6 3.4 3 1 0 3 3 3 1 BAR domain of APPL family CAF-1_p150 PF11600.8 GAM20383.1 - 0.0071 16.1 33.4 0.026 14.2 33.4 1.9 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Afi1 PF07792.12 GAM20383.1 - 2.3 8.7 9.1 6.1 7.3 9.1 1.7 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Response_reg PF00072.24 GAM20385.1 - 2.4e-30 105.0 0.1 1.2e-22 80.2 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 GAM20385.1 - 7.9e-18 65.0 0.0 1.9e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Y_phosphatase PF00102.27 GAM20386.1 - 1.9e-72 243.6 0.4 5.5e-72 242.1 0.4 1.8 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 GAM20386.1 - 0.00022 21.1 0.0 0.00076 19.3 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 GAM20386.1 - 0.082 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family RA PF00788.23 GAM20387.1 - 0.0019 18.8 0.1 0.6 10.8 0.0 3.4 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain TAF4 PF05236.14 GAM20388.1 - 1.2e-31 110.5 10.0 1.2e-31 110.5 10.0 5.9 5 1 0 5 5 5 2 Transcription initiation factor TFIID component TAF4 family Pkinase PF00069.25 GAM20389.1 - 1.5e-77 260.5 0.0 2.3e-77 259.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20389.1 - 1.1e-33 116.6 0.0 2.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM20389.1 - 1.9e-11 43.8 0.0 6.8e-09 35.4 0.0 2.3 1 1 1 2 2 2 2 Kinase-like FHA PF00498.26 GAM20389.1 - 1.5e-06 28.5 0.4 1.2e-05 25.6 0.4 2.5 1 1 0 1 1 1 1 FHA domain Kdo PF06293.14 GAM20389.1 - 0.00053 19.4 0.0 0.00088 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM20389.1 - 0.061 12.1 0.0 0.061 12.1 0.0 3.0 2 2 1 3 3 3 0 Fungal protein kinase MJ1316 PF04457.12 GAM20390.1 - 2.9e-12 47.2 2.1 1.3e-11 45.0 2.1 2.0 1 1 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Kelch_1 PF01344.25 GAM20393.1 - 9.2e-30 102.0 4.4 9e-11 41.2 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 GAM20393.1 - 7.1e-26 89.6 5.5 1.3e-05 25.3 0.0 6.5 4 1 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GAM20393.1 - 4.7e-25 87.3 4.7 3.8e-06 26.8 0.0 6.3 6 2 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM20393.1 - 7.1e-21 74.0 1.7 8e-05 22.8 0.0 6.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM20393.1 - 7.1e-18 63.8 1.9 0.002 18.0 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 GAM20393.1 - 2.2e-08 33.9 8.6 0.0047 16.9 0.2 5.0 5 0 0 5 5 5 2 Kelch motif FAM183 PF14886.6 GAM20393.1 - 0.072 13.8 0.3 0.15 12.8 0.3 1.5 1 0 0 1 1 1 0 FAM183A and FAM183B related Ank_2 PF12796.7 GAM20394.1 - 4.7e-24 84.8 0.0 3.1e-09 37.3 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20394.1 - 4.3e-18 65.4 0.0 6.5e-08 33.0 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20394.1 - 5e-16 58.5 0.4 4.9e-08 33.1 0.1 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20394.1 - 5.5e-16 57.0 0.0 0.0006 20.1 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 GAM20394.1 - 3.3e-13 49.4 0.0 0.023 15.2 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Inhibitor_I53 PF11714.8 GAM20394.1 - 0.13 12.4 2.4 0.31 11.3 2.4 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin WD40 PF00400.32 GAM20395.1 - 6.9e-37 124.8 15.6 1.2e-08 35.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Prp19 PF08606.11 GAM20395.1 - 1.1e-34 118.2 1.3 2.6e-34 117.0 1.3 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 GAM20395.1 - 2.9e-21 75.6 1.1 6.9e-06 26.3 0.0 5.3 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM20395.1 - 4.7e-11 42.9 1.7 0.00028 20.8 0.1 3.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM20395.1 - 0.00078 18.5 0.5 0.6 9.0 0.0 3.4 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 GAM20395.1 - 0.0023 17.3 0.4 0.024 14.0 0.1 2.6 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 GAM20395.1 - 0.0035 16.7 0.0 0.14 11.5 0.0 2.3 1 1 1 2 2 2 1 WD40-like domain zf-Nse PF11789.8 GAM20395.1 - 0.0095 15.7 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Ig_mannosidase PF17753.1 GAM20395.1 - 0.024 14.4 0.0 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 Ig-fold domain V_ATPase_I_N PF18670.1 GAM20395.1 - 0.084 13.3 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain MFS_1 PF07690.16 GAM20396.1 - 9e-26 90.6 47.5 3.9e-25 88.5 33.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Hamartin PF04388.12 GAM20396.1 - 0.67 8.6 8.7 1.1 7.9 8.7 1.3 1 0 0 1 1 1 0 Hamartin protein DUF957 PF06117.11 GAM20397.1 - 0.039 13.5 0.1 0.055 13.0 0.1 1.2 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) eIF-5_eIF-2B PF01873.17 GAM20398.1 - 1.3e-31 108.9 1.5 4.1e-31 107.3 0.2 2.3 2 1 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 GAM20398.1 - 1.6e-20 73.0 1.4 1.6e-20 73.0 1.4 4.3 3 1 0 3 3 2 1 eIF4-gamma/eIF5/eIF2-epsilon PPP4R2 PF09184.11 GAM20398.1 - 0.0024 17.5 20.4 0.0061 16.2 9.5 2.2 2 0 0 2 2 2 2 PPP4R2 Lenti_VIF_2 PF07401.12 GAM20398.1 - 0.0066 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Bovine Lentivirus VIF protein Myc_N PF01056.18 GAM20398.1 - 0.016 15.1 1.8 0.016 15.1 1.8 2.5 2 1 0 2 2 1 0 Myc amino-terminal region TLP-20 PF06088.11 GAM20398.1 - 0.063 13.2 10.9 0.08 12.8 3.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.14 GAM20398.1 - 0.1 10.9 17.9 0.0063 14.9 8.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF4820 PF16091.5 GAM20398.1 - 0.21 10.9 11.0 0.5 9.7 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Sigma70_ner PF04546.13 GAM20398.1 - 0.32 10.9 18.2 0.082 12.8 8.5 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region SMN PF06003.12 GAM20398.1 - 2 7.6 9.5 2.8 7.1 0.6 2.3 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) DUF913 PF06025.12 GAM20398.1 - 2.3 7.1 8.6 4.8 6.0 1.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 GAM20398.1 - 2.8 7.3 27.8 1.9 7.8 16.7 2.1 2 0 0 2 2 2 0 SDA1 RNA_pol_3_Rpc31 PF11705.8 GAM20398.1 - 3.1 8.0 29.1 0.2 11.9 15.5 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Prothymosin PF03247.14 GAM20398.1 - 5.3 7.5 43.5 9.4 6.7 5.6 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family PTPRCAP PF15713.5 GAM20398.1 - 9 6.6 31.7 7.8 6.8 22.0 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated 2OG-FeII_Oxy_2 PF13532.6 GAM20399.1 - 4e-19 69.6 0.0 6.3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pcc1 PF09341.10 GAM20400.1 - 1.8e-10 40.8 0.0 2.5e-10 40.3 0.0 1.2 1 1 0 1 1 1 1 Transcription factor Pcc1 FNIP PF05725.12 GAM20403.1 - 7.2e-81 266.1 45.7 1.5e-13 50.6 0.0 10.3 5 2 2 10 10 10 10 FNIP Repeat Sulfotransfer_1 PF00685.27 GAM20403.1 - 0.15 11.5 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Sulfotransferase domain ATP-synt_ab PF00006.25 GAM20404.1 - 6e-108 359.4 0.0 1.1e-107 358.5 0.0 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 GAM20404.1 - 1.5e-41 141.1 0.0 3.1e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 GAM20404.1 - 2.1e-16 60.2 0.9 3.3e-15 56.4 1.5 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain SID-1_RNA_chan PF13965.6 GAM20407.1 - 3.4e-80 270.2 33.1 4.1e-80 269.9 33.1 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 MgtC PF02308.16 GAM20407.1 - 0.51 10.7 0.0 0.51 10.7 0.0 3.2 2 2 1 3 3 3 0 MgtC family DUF1798 PF08807.10 GAM20408.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Catalase PF00199.19 GAM20409.1 - 1.8e-188 626.4 0.2 2.2e-188 626.1 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GAM20409.1 - 2e-20 72.8 0.0 4.4e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive EF-hand_1 PF00036.32 GAM20410.1 - 1.2e-20 71.5 4.7 1.9e-06 27.0 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GAM20410.1 - 6.4e-19 66.2 5.8 6.6e-05 22.5 0.0 4.9 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 GAM20410.1 - 2.8e-18 64.5 6.8 3.8e-07 29.3 0.3 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 GAM20410.1 - 5.9e-15 55.5 7.0 1.3e-11 44.7 0.8 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAM20410.1 - 4.6e-11 42.4 4.7 0.0041 16.9 0.1 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 GAM20410.1 - 1.1e-05 25.3 0.3 0.012 15.5 0.1 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 GAM20410.1 - 0.00016 22.0 0.2 3.5 8.0 0.0 3.4 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 GAM20410.1 - 0.014 15.6 0.5 18 5.6 0.0 3.4 3 0 0 3 3 3 0 Dockerin type I domain EF-hand_10 PF14788.6 GAM20410.1 - 0.26 11.2 2.3 0.38 10.7 0.3 2.3 2 0 0 2 2 2 0 EF hand Pkinase_Tyr PF07714.17 GAM20411.1 - 3.3e-59 200.3 0.0 4.7e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM20411.1 - 5.6e-58 196.4 0.0 8.4e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 GAM20411.1 - 0.00032 19.7 0.1 0.00081 18.4 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM20411.1 - 0.0012 17.7 0.1 0.0012 17.7 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAM20411.1 - 0.011 15.7 0.0 0.031 14.2 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family B2 PF11473.8 GAM20411.1 - 0.039 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA binding protein B2 Kdo PF06293.14 GAM20411.1 - 0.05 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM20411.1 - 0.16 11.2 0.0 0.4 10.0 0.0 1.6 2 0 0 2 2 2 0 Kinase-like DUF4307 PF14155.6 GAM20411.1 - 0.32 10.8 7.2 0.98 9.3 7.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) MOSC PF03473.17 GAM20412.1 - 3e-06 27.3 0.0 4.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 MOSC domain Trehalase PF01204.18 GAM20413.1 - 6.5e-13 48.3 0.1 6.7e-13 48.3 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase PF01204.18 GAM20415.1 - 6.8e-141 470.6 1.0 7.8e-141 470.4 1.0 1.0 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 GAM20415.1 - 8.5e-05 21.7 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase AGH PF17558.2 GAM20417.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Androgenic gland hormone Ank_2 PF12796.7 GAM20419.1 - 0.062 13.9 0.5 9.9 6.8 0.0 4.1 2 2 2 4 4 4 0 Ankyrin repeats (3 copies) mTERF PF02536.14 GAM20419.1 - 0.14 11.1 0.0 0.29 10.0 0.0 1.5 1 0 0 1 1 1 0 mTERF zf-UBR PF02207.20 GAM20420.1 - 7.5e-18 64.5 8.5 7.5e-18 64.5 8.5 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Orf78 PF06024.12 GAM20420.1 - 0.77 10.1 4.7 7.8 6.9 4.7 2.8 1 0 0 1 1 1 0 Orf78 (ac78) LIM PF00412.22 GAM20421.1 - 2.7e-44 149.2 66.5 7.7e-12 45.3 3.4 5.4 5 0 0 5 5 5 5 LIM domain PTEN_C2 PF10409.9 GAM20421.1 - 3e-21 75.6 0.4 3e-21 75.6 0.4 1.8 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 GAM20421.1 - 6.1e-05 22.8 0.0 6.1e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM20421.1 - 0.0011 18.6 0.0 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAM20421.1 - 0.011 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 GAM20421.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_L37e PF01907.19 GAM20422.1 - 1.3e-26 92.5 11.0 2.2e-26 91.8 11.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 GAM20422.1 - 0.00044 20.3 0.9 0.00061 19.9 0.8 1.3 1 1 0 1 1 1 1 SelR domain DZR PF12773.7 GAM20422.1 - 0.02 14.9 1.5 0.032 14.2 1.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-CCCH PF00642.24 GAM20423.1 - 4.4e-19 67.9 16.1 6.2e-10 38.7 4.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAM20423.1 - 1.4e-10 40.8 14.5 1.6e-05 24.6 2.1 2.6 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAM20423.1 - 1.9e-10 40.4 14.7 3e-06 27.1 3.0 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 GAM20423.1 - 0.0012 19.3 12.4 0.045 14.2 0.7 2.8 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GAM20423.1 - 0.003 18.2 15.4 0.094 13.4 2.7 2.8 2 1 1 3 3 3 2 Torus domain Lustrin_cystein PF14625.6 GAM20423.1 - 4.8 7.6 6.7 4.9 7.6 1.5 2.5 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain TUG-UBL1 PF11470.8 GAM20424.1 - 8.4e-18 64.4 0.3 8.4e-18 64.4 0.3 2.2 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 GAM20424.1 - 8e-13 48.4 0.2 4.7e-09 36.3 0.1 2.8 2 0 0 2 2 2 2 UBX domain PRCC PF10253.9 GAM20424.1 - 0.85 10.4 19.2 0.023 15.5 2.4 2.5 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting RhoGEF PF00621.20 GAM20425.1 - 8.7e-37 127.1 5.9 8.7e-37 127.1 5.9 2.0 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 GAM20425.1 - 1.6e-29 102.2 1.3 6.4e-14 52.1 0.2 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain IQ PF00612.27 GAM20425.1 - 0.00032 20.2 1.6 0.001 18.7 1.6 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH PF00169.29 GAM20425.1 - 0.0007 20.1 0.6 0.0021 18.6 0.4 1.9 2 0 0 2 2 2 1 PH domain CAMSAP_CH PF11971.8 GAM20425.1 - 0.0027 17.5 0.3 0.015 15.1 0.1 2.4 2 0 0 2 2 2 1 CAMSAP CH domain PH_13 PF16652.5 GAM20425.1 - 0.0034 17.2 0.9 0.01 15.7 0.9 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 GAM20425.1 - 0.041 13.7 0.3 0.2 11.5 0.3 2.2 1 1 0 1 1 1 0 PH domain PH_10 PF15411.6 GAM20425.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain Tetraspanin PF00335.20 GAM20426.1 - 0.00051 19.8 9.3 0.00051 19.8 9.3 1.9 1 1 1 2 2 2 1 Tetraspanin family DUF4728 PF15860.5 GAM20426.1 - 0.0061 17.2 6.0 0.02 15.6 6.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4728) TssN PF17555.2 GAM20426.1 - 0.26 10.6 10.3 0.33 10.3 10.3 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2975 PF11188.8 GAM20426.1 - 0.71 9.8 0.1 0.71 9.8 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) DHHC PF01529.20 GAM20426.1 - 5.6 7.1 12.1 1.2e+02 2.8 11.9 2.1 1 1 0 1 1 1 0 DHHC palmitoyltransferase Holin_SPP1 PF04688.13 GAM20426.1 - 6 7.1 7.9 0.72 10.1 0.9 2.6 2 1 1 3 3 3 0 SPP1 phage holin CoA_binding_3 PF13727.6 GAM20426.1 - 7.4 6.6 8.4 2.2 8.3 5.0 1.7 1 1 1 2 2 2 0 CoA-binding domain PRMT5_TIM PF17285.2 GAM20427.1 - 1.1e-68 231.2 1.5 1.6e-68 230.7 1.5 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 GAM20427.1 - 9.2e-68 227.5 0.0 1.4e-67 226.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 GAM20427.1 - 1.9e-50 171.2 2.7 3.2e-50 170.4 2.7 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 GAM20427.1 - 3.9e-06 26.7 0.0 6.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein AMP-binding PF00501.28 GAM20428.1 - 4.1e-97 325.4 0.0 5.4e-97 325.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM20428.1 - 0.0033 18.4 0.0 0.009 17.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CBM49 PF09478.10 GAM20429.1 - 4e-11 43.1 13.4 0.0011 19.2 0.3 5.5 6 0 0 6 6 6 3 Carbohydrate binding domain CBM49 WD40 PF00400.32 GAM20430.1 - 2.6e-21 75.5 19.0 0.00091 20.0 0.0 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM20430.1 - 7e-11 42.3 7.0 0.0014 18.9 0.1 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM20430.1 - 0.021 13.8 3.4 1.3 7.9 0.1 3.8 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PrlF_antitoxin PF15937.5 GAM20430.1 - 0.15 12.5 0.0 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 prlF antitoxin for toxin YhaV_toxin AAA PF00004.29 GAM20431.1 - 6.3e-39 133.4 0.0 1.1e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAM20431.1 - 9.8e-23 79.9 0.2 3.3e-22 78.2 0.1 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 GAM20431.1 - 1.9e-21 75.9 5.3 3.7e-21 74.9 5.3 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 GAM20431.1 - 8.3e-08 31.9 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAM20431.1 - 1.9e-06 28.2 0.3 0.035 14.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 GAM20431.1 - 8.1e-06 26.1 0.5 2.1e-05 24.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAM20431.1 - 1.7e-05 24.6 0.0 4.8e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAM20431.1 - 2.9e-05 24.5 0.4 0.00051 20.5 0.0 2.4 2 1 0 3 3 2 1 AAA ATPase domain TIP49 PF06068.13 GAM20431.1 - 5.2e-05 22.6 0.1 0.00029 20.2 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 GAM20431.1 - 0.00015 21.4 0.3 0.046 13.3 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GAM20431.1 - 0.00021 21.3 0.0 0.00072 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 GAM20431.1 - 0.00023 21.5 0.1 0.00099 19.5 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 GAM20431.1 - 0.0006 19.6 0.4 0.0038 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAM20431.1 - 0.00098 18.4 0.0 0.0022 17.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 GAM20431.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 GAM20431.1 - 0.0016 18.5 0.0 0.0042 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM20431.1 - 0.0072 16.9 0.0 0.023 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 GAM20431.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAM20431.1 - 0.0097 16.1 0.0 0.036 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAM20431.1 - 0.013 14.9 0.3 0.038 13.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAM20431.1 - 0.014 15.0 0.4 0.11 12.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 GAM20431.1 - 0.016 14.6 0.2 3.5 6.9 0.0 2.5 1 1 1 2 2 2 0 KaiC USP8_dimer PF08969.11 GAM20431.1 - 0.017 15.3 6.8 0.039 14.1 6.8 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain AAA_17 PF13207.6 GAM20431.1 - 0.048 14.1 0.1 0.16 12.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain Tma16 PF11176.8 GAM20431.1 - 0.052 13.4 1.3 0.11 12.3 1.3 1.5 1 0 0 1 1 1 0 Translation machinery-associated protein 16 KAP_NTPase PF07693.14 GAM20431.1 - 0.076 12.2 0.2 1.5 8.0 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.27 GAM20431.1 - 0.17 12.4 0.2 1.2 9.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 GAM20431.1 - 0.2 11.6 1.9 1.2 8.9 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 GAM20431.1 - 0.28 10.6 1.2 0.53 9.7 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Pkinase PF00069.25 GAM20432.1 - 5.2e-35 121.1 0.1 5.2e-35 121.1 0.1 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20432.1 - 3.6e-24 85.5 0.1 6.5e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 GAM20432.1 - 6e-16 58.8 5.3 1.2e-15 57.8 5.3 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Ank_4 PF13637.6 GAM20432.1 - 0.00035 21.1 0.0 0.013 16.1 0.0 3.2 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM20432.1 - 0.00049 20.6 0.0 0.0072 16.9 0.0 3.0 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM20432.1 - 0.0005 20.3 0.0 2.2 9.1 0.0 4.8 5 0 0 5 5 4 1 Ankyrin repeat Kdo PF06293.14 GAM20432.1 - 0.0019 17.6 0.1 0.0044 16.4 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM20432.1 - 0.004 16.8 0.9 0.009 15.6 0.3 1.8 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 GAM20432.1 - 0.027 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 GAM20432.1 - 0.05 12.4 1.9 0.83 8.4 0.3 2.1 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 GAM20432.1 - 0.1 12.5 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.7 GAM20433.1 - 5.6e-17 62.1 0.1 0.00023 21.7 0.0 4.4 2 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20433.1 - 9e-16 58.0 1.7 0.00071 20.1 0.0 6.1 4 2 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20433.1 - 3.3e-15 55.9 0.1 0.0033 17.7 0.0 7.1 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20433.1 - 1.7e-13 49.4 0.2 0.49 11.1 0.0 8.4 9 0 0 9 9 9 2 Ankyrin repeat Ank PF00023.30 GAM20433.1 - 0.059 13.8 0.5 1e+02 3.6 0.0 4.9 5 1 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.7 GAM20434.1 - 2.9e-19 69.4 0.2 9.4e-05 22.9 0.1 6.2 5 2 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20434.1 - 7.9e-19 67.8 2.7 0.00048 20.6 0.0 6.1 6 1 0 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20434.1 - 2.1e-14 53.4 0.0 0.4 11.1 0.0 8.7 6 2 3 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20434.1 - 4e-14 51.3 0.4 4.9 8.1 0.0 9.2 8 1 2 10 10 10 4 Ankyrin repeat Ank PF00023.30 GAM20434.1 - 0.0086 16.5 0.8 1.7e+02 2.9 0.1 6.0 5 2 0 5 5 5 0 Ankyrin repeat DUF3791 PF12668.7 GAM20434.1 - 0.088 12.9 0.5 0.64 10.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) Ank_2 PF12796.7 GAM20435.1 - 1.6e-26 92.7 5.5 5.2e-08 33.4 0.3 5.0 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20435.1 - 4.8e-17 62.1 8.3 1.5e-05 25.5 0.1 7.7 6 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20435.1 - 2e-14 52.3 0.5 0.62 10.8 0.0 8.6 9 1 1 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 GAM20435.1 - 8.1e-14 51.5 0.6 0.73 10.2 0.0 8.6 4 1 4 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM20435.1 - 0.0015 18.8 2.8 11 6.6 0.1 5.9 4 2 1 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 GAM20436.1 - 8.1e-21 74.4 8.2 4.7e-08 33.5 0.7 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM20436.1 - 2.9e-19 68.9 5.4 0.00069 19.9 0.0 6.4 3 1 5 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM20436.1 - 6.2e-15 55.3 8.7 3.5e-06 27.5 0.6 6.0 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20436.1 - 4.8e-10 38.8 7.8 1.9 9.3 0.1 7.9 10 1 1 11 11 11 4 Ankyrin repeat Ank PF00023.30 GAM20436.1 - 0.0072 16.7 3.9 19 5.9 0.3 5.1 2 1 2 4 4 4 1 Ankyrin repeat DUF5049 PF16468.5 GAM20436.1 - 0.024 14.5 0.3 11 6.0 0.0 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5049) DUF3666 PF12408.8 GAM20437.1 - 0.0028 16.8 0.3 0.13 11.5 0.1 2.6 2 0 0 2 2 2 1 Ribose-5-phosphate isomerase Ank_4 PF13637.6 GAM20437.1 - 0.0071 16.9 0.0 0.089 13.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20437.1 - 0.0094 16.3 0.0 45 4.5 0.0 4.1 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM20437.1 - 0.0099 16.4 0.0 0.14 12.8 0.0 2.5 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_2 PF12796.7 GAM20438.1 - 1.3e-20 73.8 2.8 1.2e-06 29.0 0.1 6.3 4 2 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM20438.1 - 1.5e-13 50.7 6.7 0.0092 16.3 0.0 10.5 8 2 4 12 12 12 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM20438.1 - 3.2e-13 49.9 8.2 0.00024 21.6 0.1 8.6 6 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20438.1 - 1e-11 43.9 3.3 5.1 8.0 0.0 10.5 11 0 0 11 11 11 2 Ankyrin repeat DUF5049 PF16468.5 GAM20438.1 - 0.0027 17.5 1.9 4.4 7.3 0.0 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF5049) Ank PF00023.30 GAM20438.1 - 0.1 13.1 2.5 2.1e+02 2.6 0.1 6.1 6 1 0 6 6 6 0 Ankyrin repeat 14-3-3 PF00244.20 GAM20439.1 - 9.2e-85 283.7 4.7 1e-84 283.5 4.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF722 PF05263.11 GAM20439.1 - 0.035 14.3 1.3 0.082 13.1 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Ank_4 PF13637.6 GAM20440.1 - 3.8e-08 33.7 3.7 2.9e-05 24.5 0.0 4.9 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM20440.1 - 1.5e-06 28.7 3.1 0.0018 18.8 0.1 3.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM20440.1 - 6.3e-06 26.4 6.0 0.33 11.3 0.0 5.5 3 1 3 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM20441.1 - 4e-12 46.6 6.3 8.5e-07 29.5 0.8 5.4 3 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20441.1 - 2.7e-07 31.0 4.4 0.053 14.1 0.3 7.0 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20441.1 - 4.6e-07 29.6 1.6 27 5.8 0.0 8.0 8 1 1 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 GAM20441.1 - 4.6e-07 30.0 11.9 0.024 14.9 0.0 7.7 7 1 2 9 9 9 3 Ankyrin repeats (many copies) ENTH PF01417.20 GAM20441.1 - 0.32 11.0 3.5 2.8 8.0 0.6 3.6 2 1 2 4 4 4 0 ENTH domain ATG16 PF08614.11 GAM20442.1 - 3e-05 24.4 29.4 3e-05 24.4 29.4 2.6 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) SIKE PF05769.11 GAM20442.1 - 6e-05 23.1 39.2 0.00042 20.3 33.6 3.4 1 1 1 2 2 2 1 SIKE family Laminin_II PF06009.12 GAM20442.1 - 0.14 12.2 18.0 0.1 12.6 7.3 3.0 2 1 0 2 2 2 0 Laminin Domain II MscS_porin PF12795.7 GAM20442.1 - 1.3 8.6 54.1 0.088 12.3 40.4 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Ank_2 PF12796.7 GAM20443.1 - 3.6e-24 85.2 0.8 1.7e-11 44.5 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM20443.1 - 2.5e-22 78.7 3.0 2e-06 28.0 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM20443.1 - 3.7e-17 62.4 3.7 6.4e-05 23.4 0.1 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20443.1 - 2.1e-15 55.2 0.4 0.00063 20.0 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 GAM20443.1 - 3.8e-14 52.4 0.2 0.0014 19.0 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Pox_A_type_inc PF04508.12 GAM20443.1 - 0.39 10.7 1.8 0.96 9.4 1.8 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DDHD PF02862.17 GAM20443.1 - 3.4 7.8 27.4 0.9 9.6 11.6 3.3 3 0 0 3 3 3 0 DDHD domain PepSY_TM PF03929.16 GAM20443.1 - 6.6 6.3 14.8 3 7.4 3.4 2.6 2 0 0 2 2 2 0 PepSY-associated TM region G-patch PF01585.23 GAM20444.1 - 1e-09 38.1 1.8 2e-09 37.2 1.8 1.6 1 0 0 1 1 1 1 G-patch domain ArlS_N PF18719.1 GAM20444.1 - 0.053 13.7 3.1 0.057 13.6 0.9 2.2 2 0 0 2 2 2 0 ArlS sensor domain G-patch_2 PF12656.7 GAM20444.1 - 0.08 13.0 0.1 0.25 11.5 0.1 1.9 1 0 0 1 1 1 0 G-patch domain Arm PF00514.23 GAM20445.1 - 2.7e-85 278.1 10.1 2.5e-12 46.4 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAM20445.1 - 1.1e-22 80.1 1.4 4.9e-09 36.5 0.1 6.6 6 1 0 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 GAM20445.1 - 1.2e-18 67.2 0.0 6.1e-09 36.2 0.0 4.9 3 2 2 5 5 4 4 HEAT repeats IBB PF01749.20 GAM20445.1 - 1.9e-16 60.3 5.4 5.6e-16 58.8 5.4 1.9 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.22 GAM20445.1 - 7.4e-16 56.9 0.3 1.8e-05 24.6 0.0 7.3 8 0 0 8 8 8 1 HEAT repeat Arm_3 PF16186.5 GAM20445.1 - 8.5e-15 54.1 2.8 3e-14 52.3 0.7 2.6 3 0 0 3 3 3 1 Atypical Arm repeat V-ATPase_H_C PF11698.8 GAM20445.1 - 2.5e-08 34.0 0.0 0.07 13.2 0.0 4.3 4 0 0 4 4 4 2 V-ATPase subunit H Arm_2 PF04826.13 GAM20445.1 - 5.8e-07 29.2 0.0 0.049 13.1 0.0 3.4 3 0 0 3 3 3 2 Armadillo-like RICTOR_V PF14668.6 GAM20445.1 - 3.6e-05 23.9 1.6 0.22 11.8 0.0 4.6 3 1 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 GAM20445.1 - 6.7e-05 22.6 0.0 3.6 7.1 0.0 4.5 3 2 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Cnd1 PF12717.7 GAM20445.1 - 0.00031 20.8 0.0 3.9 7.5 0.0 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAM20445.1 - 0.00038 19.2 0.0 0.016 13.8 0.0 2.7 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_PBS PF03130.16 GAM20445.1 - 0.0013 19.2 1.3 1.7 9.5 0.0 5.0 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat CTNNBL PF08216.11 GAM20445.1 - 0.0021 18.2 0.0 22 5.3 0.0 4.8 5 0 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.11 GAM20445.1 - 0.0054 16.1 0.0 0.067 12.5 0.0 2.1 1 1 1 2 2 2 1 Mo25-like Atx10homo_assoc PF09759.9 GAM20445.1 - 0.017 15.1 0.1 0.79 9.8 0.0 3.1 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 GAM20445.1 - 0.049 13.6 0.0 8.7 6.3 0.0 2.6 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central DUF3361 PF11841.8 GAM20445.1 - 0.23 11.4 3.2 2.9 7.8 0.4 3.4 4 1 0 4 4 4 0 Domain of unknown function (DUF3361) RRM_1 PF00076.22 GAM20446.1 - 5.5e-19 67.8 0.0 1e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM20446.1 - 3.9e-09 36.2 0.0 7.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM20446.1 - 0.0086 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RL PF17797.1 GAM20446.1 - 0.023 14.6 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 RL domain RRM_7 PF16367.5 GAM20446.1 - 0.11 12.7 0.0 2.4 8.3 0.0 2.5 1 1 0 1 1 1 0 RNA recognition motif RRM_3 PF08777.11 GAM20446.1 - 0.21 11.7 0.0 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif IBR PF01485.21 GAM20447.1 - 9.4e-19 67.4 22.0 1.9e-10 40.8 8.4 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 GAM20447.1 - 0.0085 15.9 6.3 0.0085 15.9 6.3 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 GAM20447.1 - 0.009 16.4 3.5 0.009 16.4 3.5 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 GAM20447.1 - 0.077 12.9 40.1 0.14 12.1 10.4 4.4 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Laminin_I PF06008.14 GAM20447.1 - 0.31 10.7 8.4 0.55 9.9 8.4 1.3 1 0 0 1 1 1 0 Laminin Domain I ILEI PF15711.5 GAM20448.1 - 2.1e-27 95.4 2.4 6.2e-14 52.3 0.2 2.5 2 1 0 2 2 2 2 Interleukin-like EMT inducer FNIP PF05725.12 GAM20449.1 - 0.0052 16.9 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 FNIP Repeat Holin_SPP1 PF04688.13 GAM20450.1 - 0.0012 18.9 0.6 0.0014 18.7 0.6 1.0 1 0 0 1 1 1 1 SPP1 phage holin Mucin PF01456.17 GAM20450.1 - 3.3 7.7 19.0 3.4 7.7 19.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Agenet PF05641.12 GAM20451.1 - 0.0085 16.5 0.2 0.032 14.7 0.2 2.0 2 0 0 2 2 2 1 Agenet domain LBR_tudor PF09465.10 GAM20451.1 - 0.079 12.8 0.3 0.54 10.1 0.1 2.3 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Kinesin PF00225.23 GAM20458.1 - 1.1e-98 330.3 3.1 1.1e-98 330.3 3.1 2.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAM20458.1 - 1.2e-22 80.5 0.4 5.9e-22 78.2 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding CAMSAP_CC1 PF17095.5 GAM20458.1 - 0.032 14.1 16.0 0.19 11.6 4.0 2.8 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin HOOK PF05622.12 GAM20458.1 - 0.095 10.8 35.0 0.15 10.2 35.0 1.2 1 0 0 1 1 1 0 HOOK protein ADIP PF11559.8 GAM20458.1 - 0.39 10.8 40.4 0.5 10.4 16.3 3.2 2 2 0 2 2 2 0 Afadin- and alpha -actinin-Binding FNIP PF05725.12 GAM20459.1 - 4.2e-99 324.5 36.6 6.1e-16 58.3 1.3 11.6 6 3 2 11 11 11 11 FNIP Repeat Glyco_hydro_65C PF03633.15 GAM20459.1 - 0.42 10.5 4.0 25 4.9 0.0 5.3 7 0 0 7 7 7 0 Glycosyl hydrolase family 65, C-terminal domain Neurochondrin PF05536.11 GAM20460.1 - 1.4e-33 116.2 6.0 1.3e-17 63.4 2.4 2.2 2 0 0 2 2 2 2 Neurochondrin DUF3209 PF11483.8 GAM20460.1 - 0.71 10.3 2.7 1 9.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3209) TMEM223 PF14640.6 GAM20461.1 - 6.4e-06 26.4 1.1 1.5e-05 25.2 0.5 1.8 2 0 0 2 2 2 1 Transmembrane protein 223 Acetyltransf_1 PF00583.25 GAM20462.1 - 1.9e-08 34.5 0.0 2.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM20462.1 - 7.5e-06 26.3 0.0 1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM20462.1 - 2.3e-05 24.4 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM20462.1 - 0.00034 20.5 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein FNIP PF05725.12 GAM20463.1 - 2e-55 184.7 19.8 1.9e-11 43.9 0.1 6.4 4 1 1 6 6 6 6 FNIP Repeat Putative_PNPOx PF01243.20 GAM20464.1 - 5e-21 74.7 0.0 8.1e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 GAM20464.1 - 3.8e-17 62.1 2.4 1e-16 60.7 2.4 1.8 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Rad51 PF08423.11 GAM20465.1 - 7.4e-43 146.6 0.1 1.8e-38 132.3 0.1 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 GAM20465.1 - 4.3e-10 39.5 0.0 8.1e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 GAM20465.1 - 4e-08 32.9 1.5 2.7e-07 30.2 1.5 2.2 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 GAM20465.1 - 8.8e-06 25.2 0.2 2.3e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.21 GAM20465.1 - 3.3e-05 23.5 0.2 0.003 17.1 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA PF00004.29 GAM20465.1 - 0.0031 17.9 0.0 0.0095 16.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM20465.1 - 0.0034 17.7 1.1 0.031 14.6 1.1 2.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 GAM20465.1 - 0.0074 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 GAM20465.1 - 0.014 15.1 0.0 0.044 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 GAM20465.1 - 0.029 13.8 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Mcm10 PF09332.11 GAM20465.1 - 0.14 11.5 0.8 0.23 10.8 0.8 1.2 1 0 0 1 1 1 0 Mcm10 replication factor ABC_tran PF00005.27 GAM20465.1 - 0.16 12.5 3.9 1.3 9.5 4.0 2.3 1 1 0 1 1 1 0 ABC transporter DHHC PF01529.20 GAM20467.1 - 9.4e-37 126.1 8.1 1.4e-36 125.6 8.1 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase GTP_cyclohydroI PF01227.22 GAM20469.1 - 3e-75 251.6 0.2 3.8e-75 251.2 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 GAM20469.1 - 0.0021 18.2 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 QueF-like protein POTRA_TamA_1 PF17243.2 GAM20469.1 - 0.046 13.8 0.7 6.9 6.8 0.3 2.4 2 0 0 2 2 2 0 POTRA domain TamA domain 1 HATPase_c_2 PF13581.6 GAM20469.1 - 0.062 13.3 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Condensin2nSMC PF12422.8 GAM20470.1 - 1e-49 168.5 1.4 8e-49 165.7 0.1 3.1 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit CLASP_N PF12348.8 GAM20470.1 - 0.0017 18.0 5.7 0.24 10.9 0.1 3.8 3 1 1 4 4 4 2 CLASP N terminal CCDC53 PF10152.9 GAM20470.1 - 0.0034 17.8 0.4 0.69 10.3 0.0 3.2 2 1 1 3 3 3 1 Subunit CCDC53 of WASH complex HEAT PF02985.22 GAM20470.1 - 0.0077 16.4 0.1 28 5.3 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat RasGEF PF00617.19 GAM20470.1 - 0.62 10.2 3.4 0.49 10.6 0.3 2.3 2 0 0 2 2 2 0 RasGEF domain Oxysterol_BP PF01237.18 GAM20471.1 - 1.8e-109 366.0 0.1 2.6e-109 365.5 0.1 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein XPG_N PF00752.17 GAM20472.1 - 0.11 12.9 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 XPG N-terminal domain Myotub-related PF06602.14 GAM20473.1 - 3.6e-58 197.2 0.0 6.2e-58 196.4 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 GAM20473.1 - 0.0013 18.6 0.7 0.0036 17.2 0.5 1.8 1 1 1 2 2 2 1 GRAM domain adh_short PF00106.25 GAM20475.1 - 6.7e-41 139.9 0.1 8.5e-41 139.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM20475.1 - 1.6e-29 103.1 0.0 2.2e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM20475.1 - 3.7e-05 23.7 0.0 5.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 GAM20476.1 - 3.5e-51 173.5 0.2 4.7e-51 173.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM20476.1 - 1.1e-33 116.7 0.1 1.6e-33 116.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM20476.1 - 5.8e-12 45.9 0.1 8.6e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM20476.1 - 3.9e-07 29.8 0.1 8.6e-07 28.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM20476.1 - 2.9e-06 27.3 0.0 5.9e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAM20476.1 - 0.0017 17.5 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 GAM20476.1 - 0.088 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Chlam_PMP PF02415.17 GAM20477.1 - 7.9e-07 29.2 70.6 0.3 11.6 3.4 12.4 12 0 0 12 12 12 10 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF4064 PF13273.6 GAM20477.1 - 0.025 14.8 0.1 0.18 12.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Methyltr_RsmB-F PF01189.17 GAM20478.1 - 3.1e-24 85.7 0.1 4.7e-15 55.8 0.0 2.7 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F NusB PF01029.18 GAM20478.1 - 0.29 11.4 0.0 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 NusB family AF-4 PF05110.13 GAM20478.1 - 1.8 6.6 33.7 0.39 8.7 20.2 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein MinE PF03776.14 GAM20480.1 - 1.2e-15 57.2 0.0 1.5e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE DUF1957 PF09210.11 GAM20480.1 - 0.019 15.3 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Trehalose_PPase PF02358.16 GAM20480.1 - 0.032 13.4 0.2 0.035 13.2 0.2 1.1 1 0 0 1 1 1 0 Trehalose-phosphatase BLOC1_2 PF10046.9 GAM20481.1 - 9.4e-33 112.4 4.2 1.6e-32 111.7 4.2 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 GAM20481.1 - 0.0033 16.1 1.8 0.004 15.9 1.8 1.1 1 0 0 1 1 1 1 AAA domain Nsp1_C PF05064.13 GAM20481.1 - 0.038 13.8 2.3 0.088 12.6 2.3 1.6 1 0 0 1 1 1 0 Nsp1-like C-terminal region Yuri_gagarin PF15934.5 GAM20481.1 - 0.081 12.8 0.8 0.093 12.6 0.8 1.2 1 0 0 1 1 1 0 Yuri gagarin DUF1664 PF07889.12 GAM20481.1 - 0.1 12.6 1.0 0.34 10.9 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 GAM20481.1 - 0.18 11.7 12.3 0.14 11.9 1.4 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 ParB PF08775.10 GAM20481.1 - 0.38 11.2 6.9 0.5 10.9 0.3 2.4 1 1 1 2 2 2 0 ParB family CCDC53 PF10152.9 GAM20481.1 - 0.46 10.9 13.6 0.22 11.9 6.2 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex BLI1 PF17324.2 GAM20481.1 - 0.71 10.6 4.6 1.3 9.8 4.6 1.5 1 1 0 1 1 1 0 BLOC-1 interactor 1 zf-C4H2 PF10146.9 GAM20481.1 - 5 7.4 9.7 0.51 10.6 4.6 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein ENTH PF01417.20 GAM20482.1 - 8.4e-19 67.9 1.3 1.7e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.16 GAM20482.1 - 0.00022 20.3 1.1 0.033 13.2 0.0 2.3 2 0 0 2 2 2 2 ANTH domain DnaT PF17948.1 GAM20482.1 - 0.023 14.4 0.1 0.07 12.8 0.1 1.7 1 0 0 1 1 1 0 DnaT DNA-binding domain ABC_tran_CTD PF16326.5 GAM20483.1 - 0.18 12.1 0.1 0.18 12.1 0.1 3.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain Nup35_RRM PF05172.13 GAM20484.1 - 2.7e-09 36.9 0.0 1.2e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif tRNA-synt_1e PF01406.19 GAM20485.1 - 1.1e-59 202.3 6.5 2.2e-40 138.9 3.4 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAM20485.1 - 0.014 14.2 0.4 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (M) Clathrin PF00637.20 GAM20486.1 - 2.3e-24 85.9 23.9 7.1e-16 58.4 9.3 3.0 2 1 1 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.8 GAM20486.1 - 2.8e-17 62.6 0.7 2.8e-17 62.6 0.7 2.4 3 0 0 3 3 3 1 Vacuolar protein sorting protein 11 C terminal TPR_14 PF13428.6 GAM20486.1 - 0.057 14.3 0.0 4.3 8.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3959 PF13105.6 GAM20487.1 - 1.6 8.2 10.5 2.8 7.4 10.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) PDDEXK_9 PF08011.11 GAM20488.1 - 0.025 14.5 1.5 3.9 7.4 1.5 2.7 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Amidohydro_2 PF04909.14 GAM20489.1 - 1.1e-15 58.2 0.0 1.8e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase alpha-hel2 PF14456.6 GAM20489.1 - 0.094 12.0 0.0 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 Alpha-helical domain 2 XPG_N PF00752.17 GAM20490.1 - 0.015 15.7 0.3 0.063 13.7 0.1 2.1 2 0 0 2 2 2 0 XPG N-terminal domain XPG_I PF00867.18 GAM20490.1 - 0.021 15.1 0.0 0.054 13.8 0.0 1.8 1 0 0 1 1 1 0 XPG I-region Pkinase_Tyr PF07714.17 GAM20491.1 - 9.6e-53 179.1 0.0 1.7e-52 178.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM20491.1 - 7.8e-46 156.6 0.0 2.1e-45 155.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 GAM20491.1 - 7.1e-36 123.8 0.1 1.6e-23 83.5 0.0 3.1 3 0 0 3 3 3 2 C-terminal of Roc, COR, domain LRR_8 PF13855.6 GAM20491.1 - 5.1e-28 96.6 33.8 1.4e-14 53.6 1.1 7.2 6 2 2 8 8 8 5 Leucine rich repeat Roc PF08477.13 GAM20491.1 - 1.5e-22 80.1 0.4 2.1e-16 60.2 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase LRR_4 PF12799.7 GAM20491.1 - 4.8e-19 68.1 34.5 2.9e-06 27.5 1.7 7.2 3 2 4 8 8 8 6 Leucine Rich repeats (2 copies) RhoGEF PF00621.20 GAM20491.1 - 1.4e-16 61.3 3.6 8.4e-13 48.9 1.8 3.0 2 0 0 2 2 2 2 RhoGEF domain Ras PF00071.22 GAM20491.1 - 4.5e-11 42.6 0.0 7.7e-08 32.1 0.0 2.6 2 0 0 2 2 2 2 Ras family LRR_6 PF13516.6 GAM20491.1 - 2.6e-07 30.1 23.6 3 8.1 0.1 10.1 10 0 0 10 10 10 2 Leucine Rich repeat PH_13 PF16652.5 GAM20491.1 - 6.4e-07 29.3 0.4 2.2e-06 27.5 0.4 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain LRR_1 PF00560.33 GAM20491.1 - 1.2e-06 28.2 9.4 23 6.0 0.1 8.4 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_9 PF14580.6 GAM20491.1 - 0.00015 21.3 12.2 0.0098 15.4 3.2 3.5 1 1 2 3 3 3 2 Leucine-rich repeat PH PF00169.29 GAM20491.1 - 0.012 16.1 0.0 0.043 14.3 0.0 1.9 1 0 0 1 1 1 0 PH domain Gtr1_RagA PF04670.12 GAM20491.1 - 0.014 14.8 0.0 0.037 13.4 0.0 1.7 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM20491.1 - 0.016 15.3 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_C1 PF00112.23 GAM20492.1 - 5e-72 242.5 10.8 7.6e-59 199.4 2.5 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM20492.1 - 2e-14 53.7 0.9 3.2e-14 53.1 0.9 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAM20492.1 - 0.0097 14.7 4.4 0.25 10.1 1.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Coiled PF05710.12 GAM20493.1 - 2e-18 67.0 26.1 2.3e-18 66.8 26.1 1.0 1 0 0 1 1 1 1 Coiled coil Forkhead_N PF08430.12 GAM20493.1 - 3.4 8.3 9.3 3.8 8.1 9.3 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region bMG10 PF17973.1 GAM20494.1 - 2.3e-23 82.8 0.0 9.7e-23 80.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial Alpha-2-macroglobulin MG10 domain ubiquitin PF00240.23 GAM20494.1 - 2.8e-16 59.0 0.0 1e-06 28.4 0.0 4.0 3 0 0 3 3 3 2 Ubiquitin family A2M PF00207.22 GAM20494.1 - 9.6e-12 44.6 0.1 5.8e-11 42.1 0.1 2.4 1 0 0 1 1 1 1 Alpha-2-macroglobulin family MG2 PF01835.19 GAM20494.1 - 8.4e-09 35.8 0.1 1.1e-06 29.0 0.0 3.7 4 0 0 4 4 4 1 MG2 domain A2M_BRD PF07703.14 GAM20494.1 - 3.9e-08 33.7 0.0 2.1e-07 31.4 0.0 2.4 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain Rad60-SLD PF11976.8 GAM20494.1 - 3e-07 30.2 0.7 0.00045 20.0 0.0 3.7 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Big_1 PF02369.16 GAM20494.1 - 0.1 12.6 0.1 4.2 7.4 0.0 3.3 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) Big_5 PF13205.6 GAM20494.1 - 6.5 7.5 24.6 0.27 12.0 0.1 7.0 8 0 0 8 8 8 0 Bacterial Ig-like domain BAR PF03114.18 GAM20495.1 - 0.0035 17.0 11.9 0.0063 16.2 11.9 1.4 1 0 0 1 1 1 1 BAR domain UPF0253 PF06786.12 GAM20495.1 - 0.026 14.8 0.9 0.066 13.5 0.9 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) PMC2NT PF08066.12 GAM20495.1 - 3.2 8.5 5.8 0.94 10.2 0.3 2.8 3 0 0 3 3 3 0 PMC2NT (NUC016) domain FNIP PF05725.12 GAM20496.1 - 5.3e-52 173.7 11.6 1.8e-16 60.0 0.4 9.2 7 3 3 10 10 10 8 FNIP Repeat Arm PF00514.23 GAM20496.1 - 0.24 11.5 0.5 5.2 7.3 0.0 2.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Endotoxin_N PF03945.14 GAM20497.1 - 2.9e-14 53.3 0.0 5.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.14 GAM20498.1 - 9.9e-35 120.3 0.0 1.5e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain CAP PF00188.26 GAM20499.1 - 0.0014 19.5 0.0 0.004 18.0 0.0 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family GFA PF04828.14 GAM20500.1 - 2.7e-06 27.6 2.8 2.7e-06 27.6 2.8 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ecotin PF03974.13 GAM20501.1 - 1e-43 148.2 0.1 1.2e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Ecotin SapB_2 PF03489.17 GAM20502.1 - 9.5e-06 25.6 2.1 3.4e-05 23.9 2.1 2.1 1 0 0 1 1 1 1 Saposin-like type B, region 2 Lipase_GDSL_2 PF13472.6 GAM20502.1 - 5.2e-05 23.7 0.2 0.00011 22.6 0.2 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAM20502.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cu-binding_MopE PF11617.8 GAM20502.1 - 0.74 10.0 7.0 0.24 11.6 3.4 2.2 2 0 0 2 2 2 0 Putative metal-binding motif ubiquitin PF00240.23 GAM20505.1 - 1.7e-08 34.0 0.1 6.2e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family VWA_2 PF13519.6 GAM20505.1 - 1e-06 29.3 0.0 4.6e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Ras PF00071.22 GAM20505.1 - 0.00025 20.7 0.1 0.00082 19.0 0.0 1.9 2 0 0 2 2 2 1 Ras family CDP-OH_P_transf PF01066.21 GAM20506.1 - 2.3e-12 47.5 1.1 2.3e-12 47.5 1.1 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase YihI PF04220.12 GAM20507.1 - 0.031 14.0 3.5 0.058 13.1 3.5 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) WH2 PF02205.20 GAM20507.1 - 0.048 13.5 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 0 WH2 motif SOG2 PF10428.9 GAM20507.1 - 1.6 7.9 16.6 2.6 7.1 16.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein BAR PF03114.18 GAM20508.1 - 2e-16 60.4 18.6 2.4e-16 60.1 18.6 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 GAM20508.1 - 5.7e-13 49.1 12.7 5.7e-13 49.1 12.7 1.3 1 1 0 1 1 1 1 BAR domain of APPL family BAR_2 PF10455.9 GAM20508.1 - 0.00019 20.7 15.4 0.00023 20.4 15.4 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Arfaptin PF06456.13 GAM20508.1 - 0.00043 19.9 16.1 0.00052 19.7 16.1 1.0 1 0 0 1 1 1 1 Arfaptin-like domain Med30 PF11315.8 GAM20508.1 - 0.14 12.3 13.9 0.11 12.7 2.1 3.1 1 1 1 3 3 3 0 Mediator complex subunit 30 Methyltransf_25 PF13649.6 GAM20508.1 - 0.19 12.4 1.7 0.52 11.0 0.4 2.3 2 1 1 3 3 3 0 Methyltransferase domain Sec34 PF04136.15 GAM20508.1 - 0.2 11.5 7.8 0.49 10.3 2.7 2.5 2 0 0 2 2 2 0 Sec34-like family Tup_N PF08581.10 GAM20508.1 - 0.44 10.9 10.9 8.7 6.7 7.2 3.0 2 1 0 2 2 2 0 Tup N-terminal Peptidase_M49 PF03571.15 GAM20508.1 - 0.84 7.9 11.3 0.021 13.2 4.3 1.7 2 0 0 2 2 2 0 Peptidase family M49 B5 PF03484.15 GAM20508.1 - 1.2 9.5 3.4 3.7 7.9 3.4 1.8 1 1 0 1 1 1 0 tRNA synthetase B5 domain FKBP_C PF00254.28 GAM20509.1 - 4.1e-30 103.9 0.0 4.6e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-CDGSH PF09360.10 GAM20510.1 - 2.7e-22 78.7 3.4 6.9e-11 42.2 0.2 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type MSL2-CXC PF16682.5 GAM20510.1 - 0.075 13.2 4.1 5 7.3 0.3 2.5 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Metallophos_C PF14008.6 GAM20511.1 - 2.7e-19 69.8 1.6 2.7e-19 69.8 1.6 4.0 3 1 1 4 4 4 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 GAM20511.1 - 8.6e-18 65.6 0.2 1.6e-17 64.7 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GAM20511.1 - 4.4e-16 59.2 0.4 4.4e-16 59.2 0.4 2.5 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain fn3_PAP PF17808.1 GAM20511.1 - 1.8e-05 24.8 0.4 0.0019 18.3 0.4 2.8 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase BRO1 PF03097.18 GAM20512.1 - 5.4e-108 361.2 11.9 5.4e-108 361.2 11.9 2.1 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GAM20512.1 - 9.2e-72 241.8 18.7 9.2e-72 241.8 18.7 2.5 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Sec8_exocyst PF04048.14 GAM20512.1 - 0.008 16.1 23.5 0.24 11.3 4.8 5.3 4 2 1 5 5 5 3 Sec8 exocyst complex component specific domain FUSC PF04632.12 GAM20512.1 - 5.2 5.5 5.6 11 4.3 0.3 2.7 3 1 0 3 3 3 0 Fusaric acid resistance protein family Cation_ATPase_C PF00689.21 GAM20513.1 - 1.3e-43 148.8 7.6 1.3e-43 148.8 7.6 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAM20513.1 - 3.7e-35 121.1 0.3 3.7e-35 121.1 0.3 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAM20513.1 - 5.2e-21 74.5 0.1 1.1e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM20513.1 - 6.2e-15 56.1 2.4 1e-14 55.3 0.5 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM20513.1 - 3e-14 52.5 0.2 8.9e-14 50.9 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM20513.1 - 0.00046 20.0 0.5 0.033 13.9 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.8 GAM20513.1 - 0.023 15.1 0.6 14 6.2 0.0 2.8 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal DUF1980 PF09323.10 GAM20513.1 - 0.11 12.4 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Dicty_REP PF05086.12 GAM20513.1 - 0.25 9.3 0.7 0.38 8.7 0.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Wzy_C PF04932.15 GAM20513.1 - 2.7 7.6 7.3 0.53 9.9 0.1 3.0 3 1 0 3 3 3 0 O-Antigen ligase WW PF00397.26 GAM20514.1 - 2.6e-23 81.8 6.4 3e-11 43.2 1.0 2.5 2 0 0 2 2 2 2 WW domain C2 PF00168.30 GAM20514.1 - 1.4e-10 41.3 1.2 9.1e-06 25.9 0.2 2.5 2 0 0 2 2 2 2 C2 domain ACT_4 PF13291.6 GAM20514.1 - 0.11 13.1 0.3 0.11 13.1 0.3 2.2 3 0 0 3 3 3 0 ACT domain DUF3657 PF12394.8 GAM20514.1 - 0.17 12.5 0.7 1.8 9.2 0.1 2.6 2 0 0 2 2 2 0 Protein FAM135 CLN5 PF15014.6 GAM20515.1 - 2.6e-16 60.2 6.9 3.5e-16 59.7 6.9 1.1 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 Man-6-P_recep PF02157.15 GAM20515.1 - 9.1e-08 31.5 0.2 1.8e-07 30.5 0.2 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 GAM20515.1 - 4.1e-06 26.8 0.1 7e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 Ribosomal_L22 PF00237.19 GAM20516.1 - 2.9e-36 123.8 0.7 4e-36 123.4 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ATG27 PF09451.10 GAM20517.1 - 4.5e-33 115.2 1.7 1.9e-32 113.2 1.7 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 GAM20517.1 - 1.6e-11 43.8 0.8 9e-11 41.3 0.8 2.0 1 1 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 GAM20517.1 - 4.8e-07 29.9 0.2 1.2e-05 25.5 0.3 2.2 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 GAM20517.1 - 0.0046 16.7 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Consortin_C PF15281.6 GAM20517.1 - 0.19 11.7 1.3 5.7 7.0 0.1 2.4 2 0 0 2 2 2 0 Consortin C-terminus VKG_Carbox PF05090.14 GAM20519.1 - 1.7e-07 30.4 11.9 2.5e-07 29.9 11.9 1.2 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase DUF3392 PF11872.8 GAM20519.1 - 0.064 13.5 1.1 0.19 12.0 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) UPF0160 PF03690.13 GAM20520.1 - 2.2e-128 428.4 0.0 2.5e-128 428.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) NuA4 PF09340.10 GAM20521.1 - 2e-22 78.9 0.1 2e-22 78.9 0.1 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 FSA_C PF10479.9 GAM20521.1 - 0.13 10.4 4.7 0.15 10.2 4.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 GAM20521.1 - 0.27 11.2 11.4 0.43 10.6 11.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 GAM20521.1 - 2 8.4 8.9 3.3 7.7 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Rad51 PF08423.11 GAM20522.1 - 2.1e-21 76.4 0.0 2.7e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 GAM20522.1 - 5e-06 26.0 0.0 1.1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 KaiC RecA PF00154.21 GAM20522.1 - 1.8e-05 24.3 0.0 9.4e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein CobU PF02283.16 GAM20522.1 - 3.8e-05 23.3 0.1 0.012 15.2 0.0 2.3 1 1 1 2 2 2 2 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_25 PF13481.6 GAM20522.1 - 7.8e-05 22.3 0.0 0.00015 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 GAM20522.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain IPT PF01745.16 GAM20522.1 - 0.013 14.9 0.1 0.032 13.6 0.0 1.7 1 1 0 1 1 1 0 Isopentenyl transferase IstB_IS21 PF01695.17 GAM20522.1 - 0.014 15.1 0.3 0.26 11.0 0.0 2.9 1 1 1 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 GAM20522.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Gag_spuma PF03276.14 GAM20522.1 - 0.15 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein SF3a60_bindingd PF12108.8 GAM20522.1 - 0.28 11.1 3.5 4.1 7.4 0.1 3.1 3 0 0 3 3 3 0 Splicing factor SF3a60 binding domain ApoL PF05461.11 GAM20523.1 - 0.063 12.6 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein L Cpn60_TCP1 PF00118.24 GAM20525.1 - 3.6e-53 180.9 5.2 5.8e-53 180.2 5.2 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family F5_F8_type_C PF00754.25 GAM20526.1 - 3.9e-18 65.8 0.0 9.5e-18 64.5 0.0 1.6 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.10 GAM20526.1 - 3.9e-17 62.2 0.7 9.4e-17 61.0 0.7 1.6 1 0 0 1 1 1 1 H-type lectin domain Hist_deacetyl PF00850.19 GAM20527.1 - 4.5e-91 305.5 0.0 9e-91 304.5 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Zn_Tnp_IS1 PF03811.13 GAM20527.1 - 0.017 14.8 2.5 0.049 13.4 2.5 1.8 1 0 0 1 1 1 0 InsA N-terminal domain DBC1 PF14443.6 GAM20527.1 - 0.069 13.1 0.2 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 DBC1 Xpo1 PF08389.12 GAM20528.1 - 3.4e-09 36.9 0.2 3.4e-09 36.9 0.2 4.7 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 GAM20528.1 - 9.5e-05 22.2 0.1 0.00048 20.0 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 GAM20528.1 - 0.052 13.6 0.7 9.5 6.3 0.0 3.4 4 0 0 4 4 4 0 Importin 13 repeat RhoGEF PF00621.20 GAM20528.1 - 0.19 12.0 3.3 0.77 10.0 3.3 2.1 1 0 0 1 1 1 0 RhoGEF domain Ribosomal_L27A PF00828.19 GAM20529.1 - 7e-20 72.0 0.0 9e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ank_2 PF12796.7 GAM20530.1 - 3.1e-50 168.7 26.0 4.2e-09 36.9 0.4 8.1 3 2 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20530.1 - 1.3e-41 140.4 14.1 1.9e-05 25.1 0.1 12.9 9 3 4 13 13 13 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20530.1 - 3.9e-41 138.6 19.0 0.00038 20.7 0.1 17.1 3 3 15 18 18 18 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20530.1 - 1.3e-21 74.3 6.9 1.1 10.0 0.0 15.1 15 1 2 17 17 17 3 Ankyrin repeat Ank PF00023.30 GAM20530.1 - 2.8e-10 40.1 3.8 14 6.3 0.0 11.9 8 3 4 12 12 12 1 Ankyrin repeat DUF5049 PF16468.5 GAM20530.1 - 1.1e-09 38.0 5.3 22 5.1 0.0 12.0 10 4 6 16 16 16 1 Domain of unknown function (DUF5049) DUF1707 PF08044.11 GAM20530.1 - 0.018 15.1 4.2 3.9 7.6 0.1 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1707) Piezo_RRas_bdg PF12166.8 GAM20531.1 - 0.14 11.5 1.2 0.23 10.7 1.2 1.4 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Ribosomal_L5_C PF00673.21 GAM20532.1 - 1.2e-21 76.7 0.1 1.8e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAM20532.1 - 1.4e-18 66.9 0.0 3.4e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L5 DUF5052 PF16475.5 GAM20533.1 - 0.01 15.5 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) Ribosomal_S19e PF01090.19 GAM20534.1 - 6.1e-51 171.7 0.0 8e-51 171.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L21e PF01157.18 GAM20536.1 - 1.6e-41 140.2 5.2 1.7e-41 140.2 4.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Phosphoesterase PF04185.14 GAM20538.1 - 1.6e-75 254.6 2.7 2.6e-75 253.8 2.7 1.3 1 0 0 1 1 1 1 Phosphoesterase family Coiled PF05710.12 GAM20540.1 - 0.0018 19.0 4.1 0.0077 17.0 4.1 1.8 1 1 0 1 1 1 1 Coiled coil Kelch_6 PF13964.6 GAM20541.1 - 1.1e-35 120.7 20.1 3.8e-09 36.5 0.4 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 GAM20541.1 - 3.6e-35 119.3 18.9 9.2e-11 41.2 0.5 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 GAM20541.1 - 3.7e-33 113.0 25.1 3.4e-08 33.3 0.5 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAM20541.1 - 5.4e-33 112.6 14.9 1.5e-09 37.9 0.1 7.5 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM20541.1 - 2.3e-24 85.1 12.1 0.00024 21.0 0.3 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM20541.1 - 1.2e-23 82.2 22.1 4e-07 29.8 0.4 6.7 6 0 0 6 6 6 6 Kelch motif F-box PF00646.33 GAM20541.1 - 2.1e-09 37.0 0.6 2.1e-09 37.0 0.6 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAM20541.1 - 3e-07 30.2 0.1 8.4e-07 28.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 GAM20541.1 - 0.00018 21.3 1.1 0.00029 20.7 0.0 1.8 2 0 0 2 2 2 1 F-box RAG2 PF03089.14 GAM20541.1 - 0.0068 15.4 1.9 0.024 13.6 0.0 2.5 3 1 0 3 3 3 1 Recombination activating protein 2 Secretin_N_2 PF07655.13 GAM20541.1 - 3 8.4 14.9 25 5.5 12.9 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4061 PF13270.6 GAM20542.1 - 0.11 12.8 1.0 3.2 8.1 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) RasGEF PF00617.19 GAM20543.1 - 4.5e-32 111.7 2.0 1.2e-31 110.3 2.0 1.8 1 0 0 1 1 1 1 RasGEF domain RhoGAP PF00620.27 GAM20543.1 - 3.2e-15 56.3 0.1 9.5e-15 54.7 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.20 GAM20543.1 - 1.7e-13 50.7 0.1 1.3e-12 47.8 0.0 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif Ly49 PF08391.10 GAM20543.1 - 5.1 7.5 7.3 22 5.4 7.3 2.1 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Pribosyltran_N PF13793.6 GAM20544.1 - 4.7e-44 149.1 1.2 1.6e-43 147.4 0.1 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAM20544.1 - 3.4e-30 105.5 4.8 3.7e-27 95.5 1.4 3.2 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAM20544.1 - 8.4e-07 28.6 1.2 1.8e-06 27.5 0.8 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Spc7 PF08317.11 GAM20547.1 - 6.2e-15 54.9 7.4 6.2e-15 54.9 7.4 2.7 2 1 1 3 3 3 1 Spc7 kinetochore protein Knl1_RWD_C PF18210.1 GAM20547.1 - 0.00014 22.3 0.0 0.00041 20.8 0.0 1.9 1 0 0 1 1 1 1 Knl1 RWD C-terminal domain XhlA PF10779.9 GAM20547.1 - 5 7.4 5.5 1.3 9.2 0.7 2.6 2 0 0 2 2 2 0 Haemolysin XhlA DUF2070 PF09843.9 GAM20548.1 - 0.00049 18.5 1.5 0.0006 18.2 1.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) YqfD PF06898.11 GAM20548.1 - 0.083 11.7 0.3 0.083 11.7 0.3 1.5 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD GFA PF04828.14 GAM20549.1 - 0.066 13.6 5.9 0.17 12.3 5.9 1.8 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-CCHC_2 PF13696.6 GAM20549.1 - 0.14 12.0 0.8 0.14 12.0 0.8 2.8 3 0 0 3 3 3 0 Zinc knuckle N_BRCA1_IG PF16158.5 GAM20550.1 - 9.2e-15 55.2 0.6 1e-13 51.9 0.0 2.9 3 0 0 3 3 3 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 GAM20550.1 - 2.4e-05 24.0 6.1 5.2e-05 23.0 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Vps39_2 PF10367.9 GAM20550.1 - 0.0068 16.8 3.0 2.2 8.8 0.4 3.4 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 2 Ly49 PF08391.10 GAM20550.1 - 7.7 6.9 6.9 28 5.1 6.9 1.9 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region MTHFR PF02219.17 GAM20551.1 - 9e-118 392.8 0.0 2e-117 391.6 0.0 1.5 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase Aconitase PF00330.20 GAM20552.1 - 1.2e-152 509.1 0.0 1.7e-152 508.7 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAM20552.1 - 1.4e-45 154.9 0.0 2.6e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ThiF PF00899.21 GAM20553.1 - 1.5e-81 273.4 0.0 5.9e-55 186.3 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GAM20553.1 - 2.9e-37 128.9 1.7 4.6e-37 128.3 0.5 2.0 2 1 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 GAM20553.1 - 7e-18 65.1 0.1 2.3e-17 63.5 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 GAM20553.1 - 2.8e-10 40.2 0.1 1.1e-09 38.3 0.1 2.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Inhibitor_I29 PF08246.12 GAM20554.1 - 7.4e-12 45.5 0.0 2e-11 44.2 0.0 1.7 2 1 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) MotB_plug PF13677.6 GAM20554.1 - 0.079 12.6 0.4 0.3 10.7 0.1 2.2 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB Podoplanin PF05808.11 GAM20554.1 - 0.15 12.1 4.3 0.33 11.0 4.3 1.6 1 1 0 1 1 1 0 Podoplanin DUF1772 PF08592.11 GAM20554.1 - 1.4 9.2 8.9 0.56 10.5 5.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Peptidase_C1 PF00112.23 GAM20555.1 - 1.3e-49 169.2 8.7 3.2e-49 168.0 8.7 1.6 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 GAM20555.1 - 5e-15 56.4 2.8 5e-15 56.4 2.8 2.7 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Peptidase_C1_2 PF03051.15 GAM20555.1 - 0.002 17.0 0.2 1.1 7.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family SOG2 PF10428.9 GAM20555.1 - 0.29 10.3 20.2 0.4 9.8 20.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 GAM20555.1 - 3.7 6.3 4.8 4.6 6.0 4.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Xpo1 PF08389.12 GAM20557.1 - 6.2e-12 45.8 0.9 6.2e-12 45.8 0.9 5.2 5 2 1 6 6 6 1 Exportin 1-like protein IBN_N PF03810.19 GAM20557.1 - 0.03 14.2 0.8 0.32 10.9 0.1 3.3 3 0 0 3 3 3 0 Importin-beta N-terminal domain Complex1_LYR PF05347.15 GAM20558.1 - 3e-06 27.2 0.4 1.4e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAM20558.1 - 0.0086 16.8 0.2 0.015 16.1 0.2 1.5 1 1 0 1 1 1 1 Complex1_LYR-like RRM_1 PF00076.22 GAM20559.1 - 1.4e-17 63.2 0.0 2.7e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM20559.1 - 8.1e-07 28.7 0.0 9e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM20559.1 - 0.04 13.8 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF4748 PF15932.5 GAM20560.1 - 0.13 12.0 3.7 0.17 11.7 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) PKI PF02827.16 GAM20560.1 - 3.9 7.8 7.5 5.4 7.3 7.5 1.2 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Activator_LAG-3 PF11498.8 GAM20560.1 - 8.4 5.2 21.9 8 5.3 21.9 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AAA PF00004.29 GAM20563.1 - 2.2e-15 57.2 0.0 8.5e-15 55.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM20563.1 - 1.6e-13 51.1 0.0 4.6e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM20563.1 - 2.9e-11 44.1 0.0 2.3e-10 41.1 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 GAM20563.1 - 5.1e-08 32.9 0.2 1.3e-07 31.7 0.2 1.6 1 0 0 1 1 1 1 AAA lid domain TniB PF05621.11 GAM20563.1 - 6.1e-06 25.8 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Cdc6_C PF09079.11 GAM20563.1 - 6.9e-05 22.7 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_19 PF13245.6 GAM20563.1 - 0.00078 19.8 0.1 0.0047 17.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 GAM20563.1 - 0.0027 17.7 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_11 PF13086.6 GAM20563.1 - 0.022 14.6 0.0 0.022 14.6 0.0 3.6 3 1 0 4 4 3 0 AAA domain AAA_30 PF13604.6 GAM20563.1 - 0.023 14.4 0.0 0.07 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM20563.1 - 0.044 13.3 0.0 0.32 10.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GAM20563.1 - 0.084 12.8 0.2 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 GAM20563.1 - 0.11 12.4 0.0 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 GAM20563.1 - 0.15 12.5 1.9 0.24 11.8 0.0 2.4 3 0 0 3 3 2 0 RNA helicase ResIII PF04851.15 GAM20563.1 - 0.19 11.7 0.0 0.19 11.7 0.0 2.6 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 GAM20563.1 - 0.36 11.4 0.0 0.36 11.4 0.0 3.5 3 1 0 3 3 2 0 AAA domain Nrap_D3 PF17404.2 GAM20564.1 - 3e-37 128.2 0.0 7.7e-37 126.8 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D5 PF17406.2 GAM20564.1 - 6.3e-34 117.1 0.6 2.8e-31 108.5 0.1 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 GAM20564.1 - 1e-32 113.3 0.2 9.4e-32 110.2 0.4 2.6 2 1 0 2 2 2 1 Nrap protein domain 1 Nrap_D2 PF17403.2 GAM20564.1 - 1.5e-27 96.3 0.8 5.7e-26 91.1 0.1 2.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 GAM20564.1 - 1.4e-23 83.4 0.3 2.9e-23 82.4 0.3 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D6 PF17407.2 GAM20564.1 - 6.8e-20 71.7 1.5 1.1e-18 67.8 0.0 2.9 3 0 0 3 3 3 1 Nrap protein domain 6 CDC45 PF02724.14 GAM20564.1 - 2.5 6.3 12.7 3.9 5.7 12.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Cob_adeno_trans PF01923.18 GAM20565.1 - 1e-52 178.6 0.0 1.2e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DTW PF03942.15 GAM20566.1 - 5.9e-37 127.3 0.7 9.7e-37 126.6 0.7 1.3 1 0 0 1 1 1 1 DTW domain AAA_12 PF13087.6 GAM20567.1 - 2.8e-45 154.4 0.5 5.5e-45 153.4 0.5 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM20567.1 - 2.6e-27 96.2 5.3 2.9e-26 92.8 5.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM20567.1 - 3.5e-09 36.6 0.0 0.00026 20.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAM20567.1 - 1.4e-08 35.2 1.6 1.1e-07 32.3 1.6 2.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 GAM20567.1 - 6.5e-08 32.2 0.6 9.5e-06 25.1 0.1 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 GAM20567.1 - 0.00015 22.1 0.1 0.021 15.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 GAM20567.1 - 0.0021 17.6 0.0 0.031 13.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.6 GAM20567.1 - 0.003 17.9 0.0 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 GAM20567.1 - 0.0043 17.5 0.2 0.046 14.1 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 GAM20567.1 - 0.0099 15.9 0.1 0.069 13.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAM20567.1 - 0.01 15.4 6.2 0.016 14.7 3.6 2.7 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.17 GAM20567.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein DEAD PF00270.29 GAM20567.1 - 0.067 13.0 0.2 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Prefoldin_3 PF13758.6 GAM20567.1 - 0.092 12.8 0.6 0.65 10.1 0.6 2.6 1 1 0 1 1 1 0 Prefoldin subunit AAA_25 PF13481.6 GAM20567.1 - 0.12 11.9 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAM20567.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ank_2 PF12796.7 GAM20568.1 - 3.8e-30 104.3 6.4 3.9e-12 46.6 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM20568.1 - 1.5e-23 80.3 0.3 0.00014 22.0 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 GAM20568.1 - 9.5e-22 77.1 1.2 2.1e-06 28.2 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM20568.1 - 4.8e-21 74.2 0.1 9.6e-05 22.7 0.0 5.2 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 GAM20568.1 - 3e-14 52.9 1.6 1.2e-05 25.5 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) RabGAP-TBC PF00566.18 GAM20569.1 - 1.2e-35 123.1 7.1 1.8e-34 119.3 7.1 2.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain OSCP PF00213.18 GAM20570.1 - 1.9e-14 54.2 3.6 2.1e-14 54.0 0.1 2.1 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit Ins_allergen_rp PF06757.13 GAM20570.1 - 0.23 11.4 4.9 0.98 9.4 0.0 3.0 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification PIN_9 PF18477.1 GAM20570.1 - 1.3 9.4 4.2 1 9.7 2.1 1.9 2 1 0 2 2 2 0 PIN like domain CENP-H PF05837.12 GAM20570.1 - 2.4 8.6 6.7 0.57 10.6 1.7 2.4 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Phage_holin_3_3 PF16083.5 GAM20571.1 - 0.096 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III SAICAR_synt PF01259.18 GAM20572.1 - 4.4e-51 173.9 0.1 5.4e-51 173.6 0.1 1.1 1 0 0 1 1 1 1 SAICAR synthetase Cation_efflux PF01545.21 GAM20574.1 - 4.1e-43 147.4 7.4 5e-43 147.2 7.4 1.1 1 0 0 1 1 1 1 Cation efflux family ERCC4 PF02732.15 GAM20575.1 - 3.2e-07 30.7 0.9 6e-06 26.6 0.1 2.8 3 0 0 3 3 3 1 ERCC4 domain PcfK PF14058.6 GAM20575.1 - 2.6 8.4 7.9 8.9 6.6 0.1 2.5 2 0 0 2 2 2 0 PcfK-like protein MaoC_dehydratas PF01575.19 GAM20576.1 - 2.6e-30 104.5 0.0 1.8e-29 101.8 0.0 1.9 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GAM20576.1 - 2e-08 34.5 0.0 1.7e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase FKBP_C PF00254.28 GAM20577.1 - 4.3e-16 59.0 0.0 4.4e-11 43.0 0.0 2.6 3 0 0 3 3 3 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 GAM20577.1 - 1.2e-07 31.2 1.7 0.00082 19.1 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM20577.1 - 3.4e-07 29.9 1.6 0.0028 17.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat FKBP_N_2 PF18023.1 GAM20577.1 - 0.00012 22.1 0.0 0.0019 18.3 0.0 2.8 2 1 0 2 2 2 1 BDBT FKBP like N-terminal MIT PF04212.18 GAM20577.1 - 0.00015 21.8 1.1 0.00026 21.0 0.3 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 GAM20577.1 - 0.00019 22.0 1.3 0.025 15.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM20577.1 - 0.00022 21.6 1.1 0.14 12.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM20577.1 - 0.0036 17.8 0.2 0.092 13.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM20577.1 - 0.011 15.8 0.0 0.034 14.2 0.0 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 GAM20577.1 - 0.17 12.2 0.8 5.2 7.4 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat HgmA PF04209.13 GAM20578.1 - 3.1e-211 701.6 0.5 3.5e-211 701.4 0.5 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ank_2 PF12796.7 GAM20580.1 - 7.4e-06 26.5 2.4 0.097 13.3 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20580.1 - 0.00099 19.6 1.2 1.6 9.4 0.1 5.1 5 1 0 5 5 5 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 GAM20580.1 - 0.0048 16.8 5.8 0.39 10.7 0.7 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 GAM20580.1 - 0.0066 16.7 0.8 1.5 9.2 0.0 4.7 4 2 2 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20580.1 - 0.013 15.9 4.2 52 4.9 0.0 7.2 8 0 0 8 8 8 0 Ankyrin repeat DFRP_C PF16543.5 GAM20581.1 - 7.2e-22 77.7 2.2 7.2e-22 77.7 2.2 4.9 4 2 1 5 5 5 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 GAM20581.1 - 5.6e-06 26.1 0.6 5.6e-06 26.1 0.6 2.9 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAM20581.1 - 2.9e-05 23.8 6.8 9.1e-05 22.2 0.4 3.1 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 GAM20581.1 - 0.00094 19.9 1.6 0.00094 19.9 1.6 3.9 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 GAM20581.1 - 0.0036 17.3 3.0 0.0036 17.3 3.0 3.4 3 1 0 3 3 3 1 Zinc finger domain zf-CCCH_2 PF14608.6 GAM20581.1 - 0.035 14.6 11.0 0.089 13.3 2.6 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger MFAP1 PF06991.11 GAM20582.1 - 1.5 8.6 13.5 0.96 9.3 11.5 1.5 1 1 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Ureide_permease PF07168.11 GAM20582.1 - 2 7.1 4.3 2.4 6.8 4.3 1.1 1 0 0 1 1 1 0 Ureide permease Neur_chan_memb PF02932.16 GAM20582.1 - 2.3 8.2 9.6 2.5 8.1 9.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 GAM20582.1 - 2.5 7.4 5.9 2.9 7.2 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.22 GAM20582.1 - 6.3 5.9 7.5 6.8 5.8 7.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Aminotran_5 PF00266.19 GAM20583.1 - 3.4e-16 59.2 0.1 1.4e-15 57.2 0.1 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 GAM20583.1 - 3.5e-16 58.9 0.0 1.1e-15 57.3 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 GAM20583.1 - 0.00016 21.1 0.1 0.00029 20.3 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GAM20583.1 - 0.0019 16.8 0.0 0.003 16.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NifW PF03206.14 GAM20583.1 - 0.057 13.9 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 Nitrogen fixation protein NifW IQ_SEC7_PH PF16453.5 GAM20583.1 - 0.076 13.0 0.1 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 PH domain Tna_leader PF08053.11 GAM20583.1 - 0.17 11.9 0.2 0.55 10.3 0.2 1.9 1 0 0 1 1 1 0 Tryptophanase operon leader peptide DUF4148 PF13663.6 GAM20583.1 - 2.1 8.6 6.9 7.3 6.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Phosphoesterase PF04185.14 GAM20584.1 - 1e-88 297.9 4.4 1.4e-88 297.5 4.4 1.1 1 0 0 1 1 1 1 Phosphoesterase family NADHdh_A3 PF14987.6 GAM20585.1 - 6.6 7.1 10.4 1.2 9.4 5.5 2.2 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DUF4175 PF13779.6 GAM20585.1 - 9.9 3.9 16.8 13 3.5 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Myotub-related PF06602.14 GAM20586.1 - 1.9e-128 428.3 0.0 3.8e-128 427.4 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PX PF00787.24 GAM20586.1 - 2.5e-16 59.6 0.2 1.2e-15 57.5 0.2 2.2 1 0 0 1 1 1 1 PX domain PH PF00169.29 GAM20586.1 - 4.9e-10 39.9 0.7 1.9e-09 38.0 0.0 2.4 2 0 0 2 2 2 1 PH domain Y_phosphatase3 PF13350.6 GAM20586.1 - 0.00012 22.1 0.0 0.0003 20.8 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GAM20586.1 - 0.0012 18.7 0.0 0.0068 16.2 0.0 2.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM20586.1 - 0.0027 17.3 0.8 0.012 15.2 0.0 2.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase GRAM PF02893.20 GAM20586.1 - 0.15 12.0 2.1 0.21 11.5 0.0 2.3 3 0 0 3 3 3 0 GRAM domain Syntaxin_2 PF14523.6 GAM20587.1 - 2e-15 57.0 12.0 2e-15 57.0 12.0 2.4 2 1 0 2 2 2 1 Syntaxin-like protein Phage_SSB PF16773.5 GAM20587.1 - 0.061 13.4 1.2 0.1 12.6 0.1 1.9 2 0 0 2 2 2 0 Lactococcus phage single-stranded DNA binding protein FAM76 PF16046.5 GAM20587.1 - 0.55 9.5 6.9 0.71 9.2 6.9 1.3 1 0 0 1 1 1 0 FAM76 protein Syntaxin_2 PF14523.6 GAM20588.1 - 2e-20 73.1 6.8 2e-20 73.1 6.8 2.7 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 GAM20588.1 - 1.4e-12 47.4 0.0 3e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 GAM20588.1 - 2.5e-05 24.1 4.9 2.5e-05 24.1 4.9 2.7 2 1 0 2 2 2 1 Syntaxin ATG16 PF08614.11 GAM20588.1 - 0.14 12.3 12.6 0.017 15.3 7.1 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HsbA PF12296.8 GAM20588.1 - 1.2 9.6 7.1 6.9 7.1 1.9 2.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A AT_hook PF02178.19 GAM20589.1 - 0.0042 16.8 3.6 0.015 15.1 3.6 1.9 1 0 0 1 1 1 1 AT hook motif Ank_2 PF12796.7 GAM20590.1 - 2.4e-44 149.8 0.1 2.3e-16 60.1 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20590.1 - 1.1e-37 127.9 6.1 3.3e-11 43.5 0.1 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) DHHC PF01529.20 GAM20590.1 - 3.5e-29 101.6 11.1 3.5e-29 101.6 11.1 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.30 GAM20590.1 - 1.4e-26 91.7 0.7 9.1e-07 29.1 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 GAM20590.1 - 3.3e-25 87.8 1.4 2.7e-07 30.7 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20590.1 - 1.8e-24 83.1 4.8 6.5e-06 26.1 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat PRA1 PF03208.19 GAM20591.1 - 5e-23 81.3 2.7 7.5e-23 80.7 2.7 1.3 1 0 0 1 1 1 1 PRA1 family protein DUF295 PF03478.18 GAM20591.1 - 0.0022 17.5 0.0 0.0086 15.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF295) Rep_trans PF02486.19 GAM20591.1 - 0.049 13.4 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Replication initiation factor DPM3 PF08285.11 GAM20591.1 - 7.4 6.8 7.0 5.1 7.4 3.2 2.1 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RRM_1 PF00076.22 GAM20592.1 - 0.00058 19.6 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hEGF PF12661.7 GAM20593.1 - 0.015 15.9 6.6 0.057 14.1 6.6 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.13 GAM20593.1 - 0.73 10.3 19.8 0.29 11.5 16.4 2.2 2 0 0 2 2 2 0 EGF-like domain EGF PF00008.27 GAM20593.1 - 0.77 10.1 10.7 2.4 8.5 10.7 1.8 1 0 0 1 1 1 0 EGF-like domain Toxin_2 PF00451.19 GAM20593.1 - 3.5 8.0 8.7 7.9 6.9 8.7 1.6 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 CD36 PF01130.21 GAM20594.1 - 1.8e-32 112.5 0.7 2.1e-20 72.7 0.0 2.5 2 1 0 2 2 2 2 CD36 family Ank_4 PF13637.6 GAM20595.1 - 2.4e-10 40.8 4.5 1.1e-06 29.0 0.2 4.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM20595.1 - 3.4e-10 40.4 2.6 9.1e-07 29.4 0.2 3.7 1 1 4 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM20595.1 - 7.5e-10 38.9 6.2 0.00089 19.5 0.2 5.5 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20595.1 - 9.2e-05 22.6 0.6 29 5.7 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat DDE_Tnp_4 PF13359.6 GAM20597.1 - 5.9e-15 55.3 0.2 1.8e-13 50.5 0.2 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM20597.1 - 5.1e-05 23.0 2.6 8e-05 22.4 2.6 1.4 1 1 0 1 1 1 1 Transposase DDE domain YjgF_endoribonc PF14588.6 GAM20598.1 - 4.9e-25 88.4 0.0 5.6e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 GAM20598.1 - 8.6e-14 51.6 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP DSPc PF00782.20 GAM20599.1 - 2e-24 85.9 0.0 6.6e-24 84.2 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 GAM20599.1 - 1.4e-12 47.3 0.3 0.00033 20.5 0.0 4.9 4 0 0 4 4 4 3 Gelsolin repeat Y_phosphatase PF00102.27 GAM20599.1 - 0.095 12.2 0.0 0.095 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein-tyrosine phosphatase RE_Bsp6I PF09504.10 GAM20599.1 - 0.13 11.9 0.2 0.51 9.9 0.1 2.0 2 0 0 2 2 2 0 Bsp6I restriction endonuclease EGF_2 PF07974.13 GAM20601.1 - 0.00049 20.4 12.0 0.00049 20.4 12.0 2.1 3 0 0 3 3 3 1 EGF-like domain EGF PF00008.27 GAM20601.1 - 0.013 15.8 8.3 0.013 15.8 8.3 1.9 2 0 0 2 2 2 0 EGF-like domain EB PF01683.18 GAM20601.1 - 0.2 12.0 3.5 0.48 10.7 3.5 1.6 1 0 0 1 1 1 0 EB module I-EGF_1 PF18372.1 GAM20601.1 - 0.22 11.7 9.8 0.92 9.7 8.0 2.5 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 EphA2_TM PF14575.6 GAM20601.1 - 0.28 12.1 0.7 0.54 11.2 0.7 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EGF_Tenascin PF18720.1 GAM20601.1 - 0.35 11.0 8.5 0.12 12.5 5.4 1.9 2 0 0 2 2 2 0 Tenascin EGF domain ICAT PF06384.11 GAM20603.1 - 1.8e-26 92.2 2.2 1.8e-26 92.2 2.2 1.6 2 0 0 2 2 2 1 Beta-catenin-interacting protein ICAT GvpG PF05120.12 GAM20603.1 - 0.022 14.8 0.8 0.022 14.8 0.8 2.0 2 0 0 2 2 2 0 Gas vesicle protein G Syntaxin-18_N PF10496.9 GAM20603.1 - 0.037 14.3 0.2 0.07 13.4 0.2 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus CLZ PF16526.5 GAM20603.1 - 0.16 12.4 0.6 0.16 12.4 0.6 2.9 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Abhydrolase_6 PF12697.7 GAM20604.1 - 7.9e-14 52.8 0.0 1.1e-13 52.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM20604.1 - 8.8e-06 25.5 0.1 1.3e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 GAM20604.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 GAM20604.1 - 0.00013 21.6 0.1 0.00026 20.7 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase Chlorophyllase2 PF12740.7 GAM20604.1 - 0.00084 18.3 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Palm_thioest PF02089.15 GAM20604.1 - 0.0015 18.5 0.0 0.0019 18.1 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 GAM20604.1 - 0.0029 16.9 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAM20604.1 - 0.02 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 GAM20604.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DAGK_cat PF00781.24 GAM20605.1 - 2.6e-23 82.0 0.0 4e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain FHA PF00498.26 GAM20606.1 - 5e-13 49.2 0.6 1.1e-12 48.1 0.6 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAM20606.1 - 0.017 15.4 0.0 2 8.8 0.0 2.3 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain F-box-like PF12937.7 GAM20607.1 - 4e-09 36.2 0.3 7.9e-09 35.3 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM20607.1 - 2e-07 30.7 0.7 3.9e-07 29.8 0.7 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAM20607.1 - 0.075 12.9 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 F-box Nop14 PF04147.12 GAM20608.1 - 0.51 8.5 29.6 0.52 8.5 29.6 1.0 1 0 0 1 1 1 0 Nop14-like family HIG_1_N PF04588.13 GAM20609.1 - 1.2e-08 35.0 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Gpi1 PF05024.15 GAM20610.1 - 5.5e-61 205.9 13.5 5.5e-61 205.9 13.5 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) DUF5586 PF17824.1 GAM20610.1 - 0.016 14.3 0.0 0.035 13.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5586) IBR PF01485.21 GAM20611.1 - 1.4e-21 76.4 29.3 6.4e-14 51.9 5.4 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain UBA PF00627.31 GAM20611.1 - 1.8e-05 24.5 0.1 4.8e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Dicty_REP PF05086.12 GAM20611.1 - 0.018 13.0 6.0 0.032 12.2 6.0 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TetR_C_17 PF17922.1 GAM20611.1 - 0.045 13.9 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain OTU PF02338.19 GAM20612.1 - 9.1e-17 61.7 0.1 2.3e-16 60.4 0.1 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 GAM20612.1 - 6.4e-06 25.8 2.4 0.13 11.7 0.0 3.4 1 1 0 3 3 3 2 Peptidase C65 Otubain UBA PF00627.31 GAM20612.1 - 0.0028 17.5 0.0 0.0068 16.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Mucin PF01456.17 GAM20612.1 - 0.044 13.8 10.8 0.09 12.8 10.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SprA-related PF12118.8 GAM20612.1 - 0.051 12.7 10.4 0.1 11.7 10.4 1.5 1 0 0 1 1 1 0 SprA-related family SSP160 PF06933.11 GAM20612.1 - 0.056 11.7 9.5 0.084 11.1 9.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FNIP PF05725.12 GAM20614.1 - 6.9e-46 154.2 28.9 9.7e-10 38.5 0.0 9.3 3 2 6 10 10 10 10 FNIP Repeat Pex2_Pex12 PF04757.14 GAM20614.1 - 4.7e-30 104.9 7.7 4.7e-30 104.9 7.7 2.3 2 1 0 2 2 2 1 Pex2 / Pex12 amino terminal region NGP1NT PF08153.12 GAM20615.1 - 6.9e-45 152.4 0.1 6.9e-45 152.4 0.1 2.2 2 1 0 2 2 2 1 NGP1NT (NUC091) domain Beta-lactamase PF00144.24 GAM20616.1 - 1.1e-42 146.5 0.0 1.4e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase PARP PF00644.20 GAM20617.1 - 1.1e-23 83.8 0.7 3.1e-23 82.4 0.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 GAM20617.1 - 2.7e-16 59.9 6.5 7.8e-07 29.6 0.1 3.2 3 0 0 3 3 3 2 WWE domain HARP PF07443.13 GAM20617.1 - 0.044 13.4 3.9 0.64 9.7 0.1 2.4 2 0 0 2 2 2 0 HepA-related protein (HARP) DUF4482 PF14818.6 GAM20617.1 - 1.2 10.0 11.9 1 10.2 0.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4482) Mucin PF01456.17 GAM20617.1 - 6 6.9 42.9 2.6 8.1 7.5 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Mitoc_mL59 PF18126.1 GAM20618.1 - 0.22 11.8 12.8 7.5 6.9 12.8 2.8 1 1 0 1 1 1 0 Mitochondrial ribosomal protein mL59 CactinC_cactus PF09732.9 GAM20619.1 - 2.7e-59 198.6 6.5 5.7e-59 197.5 6.5 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 GAM20619.1 - 3.2e-48 164.1 1.5 3.2e-48 164.1 1.5 2.6 3 0 0 3 3 3 1 Conserved mid region of cactin SF3A2 PF16835.5 GAM20619.1 - 0.32 11.4 3.9 3.4 8.1 0.0 2.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Band_7 PF01145.25 GAM20621.1 - 5.5e-06 26.5 13.1 7.6e-05 22.8 13.1 2.2 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 GAM20621.1 - 0.0045 16.7 0.4 0.0083 15.9 0.4 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family DUF4698 PF15769.5 GAM20621.1 - 3.1 6.7 8.6 0.11 11.5 2.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4698) Cullin PF00888.22 GAM20622.1 - 1e-189 632.2 13.5 1e-189 632.2 13.5 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 GAM20622.1 - 1.7e-28 98.5 4.7 9.9e-28 96.0 4.7 2.5 1 0 0 1 1 1 1 Cullin protein neddylation domain MukF_M PF17192.4 GAM20622.1 - 0.01 15.6 0.7 0.1 12.3 0.1 2.7 3 0 0 3 3 3 0 MukF middle domain T3SS_basalb_I PF17001.5 GAM20622.1 - 5.5 7.7 7.1 4.6 7.9 0.5 3.4 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Pkinase PF00069.25 GAM20623.1 - 1.3e-48 165.7 0.0 1.3e-48 165.7 0.0 3.7 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20623.1 - 6.4e-20 71.5 1.4 2.6e-14 53.1 0.0 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 GAM20623.1 - 0.0036 17.3 0.3 0.031 14.2 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM20623.1 - 0.0063 16.1 0.2 0.0063 16.1 0.2 3.3 4 0 0 4 4 4 1 Choline/ethanolamine kinase DUF4061 PF13270.6 GAM20624.1 - 1.1e-16 60.9 2.0 1.5e-16 60.5 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) Alpha_kinase PF02816.18 GAM20626.1 - 8.5e-63 211.8 8.4 2.5e-62 210.3 0.3 2.5 2 0 0 2 2 2 2 Alpha-kinase family SHOCT PF09851.9 GAM20626.1 - 0.0015 18.2 0.3 0.0026 17.4 0.3 1.4 1 0 0 1 1 1 1 Short C-terminal domain ArfGap PF01412.18 GAM20627.1 - 9.4e-21 74.1 0.1 2.7e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Spt20 PF12090.8 GAM20627.1 - 0.055 13.1 11.5 0.089 12.4 11.5 1.4 1 0 0 1 1 1 0 Spt20 family DUF3439 PF11921.8 GAM20627.1 - 0.065 13.2 0.1 0.065 13.2 0.1 2.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3439) TFIIA PF03153.13 GAM20627.1 - 0.11 12.5 12.3 0.14 12.1 12.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SKA1 PF07160.12 GAM20627.1 - 0.11 12.3 2.5 0.19 11.5 2.5 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 PhnA_Zn_Ribbon PF08274.12 GAM20627.1 - 4.1 7.4 6.5 18 5.4 6.5 1.9 1 1 0 1 1 1 0 PhnA Zinc-Ribbon DUF3825 PF12873.7 GAM20628.1 - 1.3e-43 149.2 4.3 1.1e-23 84.0 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF3825) Eapp_C PF10238.9 GAM20628.1 - 0.029 14.5 0.3 0.029 14.5 0.3 3.7 3 2 1 4 4 4 0 E2F-associated phosphoprotein Cytochrom_C PF00034.21 GAM20629.1 - 4.9e-13 50.0 0.0 6.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 GAM20629.1 - 3.9e-08 33.5 0.6 9.1e-08 32.3 0.6 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 GAM20629.1 - 5.3e-05 22.9 0.1 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain DUF3365 PF11845.8 GAM20629.1 - 0.14 12.5 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) ketoacyl-synt PF00109.26 GAM20630.1 - 1.6e-75 254.0 0.0 3.1e-75 253.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAM20630.1 - 2.2e-50 172.0 0.0 3.7e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 GAM20630.1 - 1.5e-42 145.5 0.0 5.9e-42 143.6 0.0 2.1 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 GAM20630.1 - 4.8e-39 133.0 3.9 1.7e-38 131.3 0.2 3.5 4 0 0 4 4 4 1 Beta-ketoacyl synthase, C-terminal domain Chal_sti_synt_N PF00195.19 GAM20630.1 - 3.1e-38 131.4 0.1 5.5e-38 130.6 0.1 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain PS-DH PF14765.6 GAM20630.1 - 5.7e-34 117.7 0.0 9.1e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Chal_sti_synt_C PF02797.15 GAM20630.1 - 6.9e-20 71.6 0.0 2e-19 70.1 0.0 1.9 2 0 0 2 2 1 1 Chalcone and stilbene synthases, C-terminal domain KAsynt_C_assoc PF16197.5 GAM20630.1 - 3.1e-19 69.5 0.0 9.1e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 GAM20630.1 - 3.2e-16 59.9 0.0 4.3e-15 56.3 0.0 3.1 4 0 0 4 4 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 GAM20630.1 - 6.2e-14 53.2 0.1 2.6e-13 51.2 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase FAE1_CUT1_RppA PF08392.12 GAM20630.1 - 1.5e-11 44.1 0.2 1.5e-11 44.1 0.2 1.8 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein Methyltransf_23 PF13489.6 GAM20630.1 - 1e-10 41.7 0.0 2.7e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 GAM20630.1 - 5e-08 33.2 0.1 3e-07 30.7 0.0 2.5 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 GAM20630.1 - 1e-07 32.5 0.0 1.4e-06 28.9 0.0 3.1 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM20630.1 - 1.8e-07 31.7 0.0 8.8e-07 29.5 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAM20630.1 - 4.4e-07 29.5 0.3 2e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM20630.1 - 2.8e-06 27.1 0.0 6.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 GAM20630.1 - 6.1e-06 25.8 1.0 1.6e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 GAM20630.1 - 1e-05 25.3 0.0 0.00013 21.8 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain ACP_syn_III_C PF08541.10 GAM20630.1 - 1.1e-05 25.5 0.0 3.1e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 GAM20630.1 - 7.7e-05 22.5 4.1 0.0043 16.9 0.2 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 GAM20630.1 - 0.00018 21.3 0.1 0.00045 20.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 GAM20630.1 - 0.0009 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 GAM20630.1 - 0.025 14.0 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ubie_methyltran PF01209.18 GAM20630.1 - 0.031 13.6 0.0 0.099 12.0 0.0 1.8 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF5347 PF17282.2 GAM20630.1 - 0.089 13.1 0.0 0.4 11.0 0.0 2.1 2 0 0 2 2 1 0 Family of unknown function (DUF5347) Methyltransf_28 PF02636.17 GAM20630.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AMP-binding PF00501.28 GAM20631.1 - 5.3e-81 272.4 0.1 6.5e-81 272.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM20631.1 - 1.8e-22 80.1 0.4 4.5e-22 78.8 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 GAM20631.1 - 1.6e-05 24.7 0.1 4e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Enoyl_reductase PF12241.8 GAM20631.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Pentapeptide PF00805.22 GAM20632.1 - 3.4e-20 71.3 37.7 8.7e-09 34.9 1.9 4.9 1 1 4 6 6 6 6 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 GAM20632.1 - 2.2e-19 69.4 53.9 3e-08 33.7 11.0 3.5 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 GAM20632.1 - 1.6e-16 60.4 0.0 3e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.6 GAM20632.1 - 1e-10 41.6 20.4 0.00097 19.2 9.2 5.1 2 1 3 5 5 5 3 Pentapeptide repeats (9 copies) CfAFP PF05264.11 GAM20632.1 - 0.01 15.8 10.5 0.019 15.0 9.6 1.9 1 1 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) BTB PF00651.31 GAM20632.1 - 0.023 14.9 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain PhyH PF05721.13 GAM20633.1 - 1.3e-08 35.4 0.1 2.5e-07 31.2 0.1 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 GAM20633.1 - 0.004 18.0 0.0 0.0079 17.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rep_fac_C PF08542.11 GAM20634.1 - 1.4e-15 57.5 0.0 2.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 GAM20634.1 - 1.3e-14 54.3 0.0 2.2e-13 50.3 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 GAM20634.1 - 4.7e-14 53.0 0.0 8.3e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAM20634.1 - 2.2e-06 27.7 0.0 5.7e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 GAM20634.1 - 5.2e-05 23.5 0.0 0.001 19.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM20634.1 - 9.1e-05 22.9 0.1 0.00098 19.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 GAM20634.1 - 0.00013 21.8 0.0 0.00055 19.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain ResIII PF04851.15 GAM20634.1 - 0.00014 21.9 0.0 0.027 14.5 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 GAM20634.1 - 0.00016 21.5 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 GAM20634.1 - 0.00028 20.6 0.0 0.00068 19.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAM20634.1 - 0.00033 20.4 0.0 0.00096 18.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAM20634.1 - 0.00078 18.9 0.0 0.0072 15.7 0.0 2.1 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 GAM20634.1 - 0.002 17.6 0.1 0.27 10.7 0.0 2.7 2 1 1 3 3 3 1 PhoH-like protein AAA_assoc_2 PF16193.5 GAM20634.1 - 0.0038 17.5 0.0 0.009 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_5 PF07728.14 GAM20634.1 - 0.01 15.8 0.0 0.038 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 GAM20634.1 - 0.011 15.5 0.3 0.24 11.2 0.0 2.7 2 1 1 3 3 3 0 DEAD/DEAH box helicase DUF815 PF05673.13 GAM20634.1 - 0.019 14.2 0.0 0.044 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 GAM20634.1 - 0.046 14.1 0.2 0.44 10.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM20634.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 GAM20634.1 - 0.099 11.9 0.2 0.46 9.7 0.2 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Rif1_N PF12231.8 GAM20635.1 - 7.3e-39 133.8 4.9 6.6e-37 127.4 4.9 2.6 1 1 0 1 1 1 1 Rap1-interacting factor 1 N terminal ORC6 PF05460.13 GAM20635.1 - 0.56 9.4 5.6 0.53 9.5 3.7 1.8 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) SR-25 PF10500.9 GAM20635.1 - 4.6 6.8 17.1 13 5.4 17.1 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF508 PF04370.12 GAM20635.1 - 8.7 6.1 13.7 25 4.6 10.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF508) PFU PF09070.11 GAM20636.1 - 2.9e-36 124.2 0.8 2.9e-36 124.2 0.8 1.9 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 GAM20636.1 - 2.2e-34 116.9 15.3 1.1e-05 26.0 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.11 GAM20636.1 - 3.4e-34 118.3 7.0 5.3e-34 117.7 7.0 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.6 GAM20636.1 - 0.0014 18.6 0.0 5.3 7.1 0.0 3.7 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region UCR_hinge PF02320.16 GAM20637.1 - 0.019 15.1 0.2 0.029 14.6 0.2 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein CX9C PF16860.5 GAM20637.1 - 0.074 13.1 0.1 0.074 13.1 0.1 2.4 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 GAM20637.1 - 0.093 13.0 1.1 7.1 7.0 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) SNF2_N PF00176.23 GAM20640.1 - 5.7e-41 140.4 0.4 1e-40 139.6 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM20640.1 - 3.5e-14 53.1 0.8 1.1e-13 51.5 0.8 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAM20640.1 - 0.00012 21.4 0.8 0.00025 20.3 0.8 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Secretin_N_2 PF07655.13 GAM20640.1 - 0.37 11.4 23.1 4.1 8.0 13.3 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain Menin PF05053.13 GAM20640.1 - 6.1 5.1 10.1 0.12 10.8 2.5 1.7 2 0 0 2 2 2 0 Menin SNF2_N PF00176.23 GAM20641.1 - 6.1e-12 44.9 0.0 9.2e-12 44.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HGWP PF03578.15 GAM20642.1 - 0.015 14.8 1.1 0.031 13.8 1.1 1.5 1 0 0 1 1 1 0 HGWP repeat Asn_synthase PF00733.21 GAM20643.1 - 4.2e-99 332.6 0.2 1.2e-95 321.2 0.2 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 GAM20643.1 - 6.2e-41 139.2 0.0 1.1e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAM20643.1 - 4e-29 101.5 0.0 7.1e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAM20643.1 - 1.5e-14 54.0 0.2 2.4e-14 53.3 0.2 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 GAM20643.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Pectate_lyase_3 PF12708.7 GAM20644.1 - 6.2e-18 65.4 21.8 9e-16 58.4 15.4 3.4 1 1 2 3 3 3 3 Pectate lyase superfamily protein RNB PF00773.19 GAM20645.1 - 4.2e-55 187.4 2.1 1.6e-53 182.2 1.9 2.4 1 1 0 1 1 1 1 RNB domain CLTH PF10607.9 GAM20646.1 - 2.7e-32 111.7 0.9 2.7e-32 111.7 0.9 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Mitofilin PF09731.9 GAM20646.1 - 4.3e-05 22.6 6.5 4.3e-05 22.6 6.5 1.6 2 0 0 2 2 2 1 Mitochondrial inner membrane protein U-box PF04564.15 GAM20646.1 - 0.0018 18.4 0.4 0.037 14.2 0.0 3.0 3 0 0 3 3 3 1 U-box domain TPR_MLP1_2 PF07926.12 GAM20646.1 - 0.013 15.5 5.3 0.041 13.9 5.3 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein LisH PF08513.11 GAM20646.1 - 0.019 14.9 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 LisH zf-RING_UBOX PF13445.6 GAM20646.1 - 0.046 13.8 0.3 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger DUF883 PF05957.13 GAM20646.1 - 0.097 13.3 2.1 0.19 12.3 2.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RapA_C PF12137.8 GAM20646.1 - 0.12 11.4 5.6 0.19 10.7 5.6 1.3 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal DUF4407 PF14362.6 GAM20646.1 - 0.21 10.9 3.0 0.37 10.1 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 GAM20646.1 - 0.26 9.8 0.1 0.39 9.2 0.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2203 PF09969.9 GAM20646.1 - 0.3 11.8 2.2 1.8 9.3 2.2 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FapA PF03961.13 GAM20646.1 - 1.2 7.6 7.0 0.38 9.3 4.3 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A RhoGEF PF00621.20 GAM20647.1 - 3e-72 242.7 23.2 7.9e-48 163.1 4.6 3.2 3 1 1 4 4 4 2 RhoGEF domain RhoGAP PF00620.27 GAM20647.1 - 1.8e-45 154.4 1.8 1.1e-44 151.9 0.7 2.4 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.6 GAM20647.1 - 2.3e-12 46.6 0.0 4.3e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM20647.1 - 8.2e-12 44.5 0.0 2.6e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 GAM20647.1 - 1.4e-09 37.4 0.0 3.4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 GAM20647.1 - 4.5e-06 27.1 0.1 2.1e-05 25.0 0.1 2.2 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 GAM20647.1 - 0.033 14.0 6.7 0.39 10.5 2.3 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 GAM20647.1 - 0.036 14.4 0.1 0.13 12.6 0.1 2.0 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Baculo_LEF-11 PF06385.12 GAM20647.1 - 0.13 12.7 2.4 0.81 10.2 0.1 3.3 3 0 0 3 3 3 0 Baculovirus LEF-11 protein SH3_9 PF14604.6 GAM20651.1 - 1.1e-20 73.2 0.0 5.4e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAM20651.1 - 7.3e-20 70.3 0.1 1.2e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 GAM20651.1 - 3.3e-18 65.1 0.0 2.2e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain DUF3104 PF11302.8 GAM20651.1 - 0.065 13.0 0.2 6.8 6.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) RRM_1 PF00076.22 GAM20652.1 - 6.7e-30 102.7 0.0 6.4e-14 51.5 0.1 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM20652.1 - 4.4e-09 36.1 0.0 2e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF1866 PF08952.11 GAM20652.1 - 0.021 14.7 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Band_7 PF01145.25 GAM20653.1 - 5.6e-32 111.2 4.2 5.6e-32 111.2 4.2 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 GAM20653.1 - 0.0054 16.5 0.5 0.012 15.3 0.5 1.7 1 1 0 1 1 1 1 SPFH domain-Band 7 family DUF2172 PF09940.9 GAM20653.1 - 0.044 14.2 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) Med26_C PF15693.5 GAM20653.1 - 0.08 13.1 0.4 0.18 11.9 0.3 1.5 1 1 0 1 1 1 0 Mediator complex subunit 26 C-terminal COPI_C PF06957.11 GAM20654.1 - 2.7e-134 447.9 0.0 3.7e-134 447.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 GAM20654.1 - 2.6e-119 399.2 0.9 5.7e-119 398.1 0.2 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 GAM20654.1 - 1.6e-45 152.1 12.0 2.5e-08 34.4 0.0 8.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM20654.1 - 4.9e-07 29.9 0.2 1.6 9.1 0.0 5.7 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM20654.1 - 0.026 13.2 4.8 0.14 10.7 2.5 3.0 1 1 2 3 3 3 0 Nucleoporin Nup120/160 HTH_9 PF08221.11 GAM20655.1 - 1.9e-12 47.1 2.2 1.2e-07 31.7 0.5 3.6 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 GAM20655.1 - 7.8e-06 25.8 8.5 0.0088 15.8 8.0 3.5 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 GAM20655.1 - 0.024 14.5 4.9 0.025 14.4 0.1 3.2 4 1 0 4 4 4 0 TFIIE alpha subunit Sel1 PF08238.12 GAM20656.1 - 4e-21 75.0 27.9 5.3e-06 26.9 0.1 9.9 10 0 0 10 10 10 5 Sel1 repeat ERp29 PF07749.12 GAM20656.1 - 0.048 14.6 0.7 3.6 8.6 0.1 2.8 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain TPR_11 PF13414.6 GAM20656.1 - 0.18 11.5 5.9 6.7 6.5 0.9 4.2 4 0 0 4 4 4 0 TPR repeat Uma2 PF05685.12 GAM20657.1 - 0.043 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative restriction endonuclease Pro-kuma_activ PF09286.11 GAM20662.1 - 1.4e-32 113.0 0.2 2.3e-32 112.3 0.2 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM20662.1 - 1e-07 31.6 1.6 1.7e-07 30.8 1.6 1.3 1 0 0 1 1 1 1 Subtilase family Lipase_3 PF01764.25 GAM20663.1 - 6.3e-14 52.1 0.0 8.3e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Cellulase PF00150.18 GAM20665.1 - 8.6e-28 97.6 0.2 1.4e-27 96.9 0.2 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M20 PF01546.28 GAM20666.1 - 6.3e-35 120.8 0.0 8.2e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM20666.1 - 5e-20 71.4 0.0 9.1e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM20666.1 - 3.2e-06 27.0 0.0 9.8e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 GAM20666.1 - 0.041 12.9 0.0 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase COX14 PF14880.6 GAM20667.1 - 9.7e-06 25.3 1.9 1.5e-05 24.7 0.1 1.8 2 0 0 2 2 2 1 Cytochrome oxidase c assembly Nic96 PF04097.14 GAM20668.1 - 5.5e-65 220.0 12.0 1.1e-64 219.0 8.7 2.5 2 1 0 2 2 2 1 Nup93/Nic96 TPR_3 PF07720.12 GAM20668.1 - 0.17 11.9 0.0 0.17 11.9 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM20668.1 - 0.26 11.5 6.4 5.5 7.3 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM20668.1 - 0.43 10.5 4.2 9.1 6.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM20668.1 - 0.82 9.6 2.7 4.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.20 GAM20669.1 - 1.3e-22 79.7 0.7 7.1e-18 64.5 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 GAM20669.1 - 1.7e-06 28.4 1.9 1.3e-05 25.6 0.3 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 GAM20669.1 - 0.0097 15.9 0.0 1.6 8.8 0.0 2.6 2 2 0 2 2 2 1 Hydrogenase-1 expression protein HyaE RanGAP1_C PF07834.11 GAM20669.1 - 0.04 13.5 0.3 0.072 12.7 0.3 1.4 1 0 0 1 1 1 0 RanGAP1 C-terminal domain TraF PF13728.6 GAM20669.1 - 0.22 11.3 2.4 0.32 10.8 0.0 2.3 2 1 0 2 2 2 0 F plasmid transfer operon protein DUF3877 PF12993.7 GAM20669.1 - 0.31 10.9 3.9 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) ThiF PF00899.21 GAM20671.1 - 1.1e-36 126.4 0.6 8.2e-36 123.6 0.0 2.1 2 0 0 2 2 2 1 ThiF family NAD_binding_7 PF13241.6 GAM20671.1 - 0.00087 19.7 0.1 0.0035 17.8 0.1 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 GAM20671.1 - 0.0036 17.6 1.6 0.018 15.3 0.9 2.5 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Glutaredoxin PF00462.24 GAM20671.1 - 0.021 15.0 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Secretin_N_2 PF07655.13 GAM20671.1 - 0.12 13.0 6.5 0.24 11.9 6.5 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Cullin PF00888.22 GAM20672.1 - 4.2e-11 42.2 0.0 5.2e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 Cullin family DnaI_N PF07319.11 GAM20672.1 - 0.0053 17.4 0.0 0.011 16.4 0.0 1.4 2 0 0 2 2 2 1 Primosomal protein DnaI N-terminus Tn7_Tnp_TnsA_C PF08721.11 GAM20672.1 - 0.071 13.8 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 TnsA endonuclease C terminal KfrA_N PF11740.8 GAM20672.1 - 0.19 12.4 0.0 0.24 12.1 0.0 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Cullin PF00888.22 GAM20673.1 - 3.8e-69 233.9 12.5 4.4e-69 233.7 12.5 1.0 1 0 0 1 1 1 1 Cullin family PHB_acc_N PF07879.11 GAM20673.1 - 0.14 12.3 1.6 7.3 6.8 0.2 2.7 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain 3HCDH_RFF PF18321.1 GAM20674.1 - 0.021 15.3 0.8 0.21 12.0 0.0 2.6 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain HsdM_N PF12161.8 GAM20674.1 - 0.024 15.3 0.5 0.054 14.1 0.5 1.6 1 0 0 1 1 1 0 HsdM N-terminal domain Hemerythrin PF01814.23 GAM20674.1 - 0.18 12.4 0.3 0.68 10.6 0.1 2.0 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain DUF2457 PF10446.9 GAM20675.1 - 0.0013 17.9 29.4 0.0015 17.8 29.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GAM20675.1 - 0.0075 14.4 24.4 0.0083 14.3 24.4 1.0 1 0 0 1 1 1 1 DNA polymerase phi NOA36 PF06524.12 GAM20675.1 - 0.033 13.5 27.6 0.044 13.1 27.6 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 GAM20675.1 - 0.034 12.4 16.4 0.038 12.2 16.4 1.0 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 GAM20675.1 - 0.097 13.0 2.5 0.12 12.6 2.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sigma70_ner PF04546.13 GAM20675.1 - 0.41 10.5 12.8 0.48 10.3 12.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CNDH2_C PF16858.5 GAM20675.1 - 0.52 10.1 7.1 0.53 10.1 7.1 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term IFT57 PF10498.9 GAM20675.1 - 0.69 8.8 6.7 0.74 8.7 6.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BUD22 PF09073.10 GAM20675.1 - 1 8.6 15.5 1.1 8.6 15.5 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAM20675.1 - 1.1 7.4 19.3 1.4 7.2 19.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 GAM20675.1 - 1.6 8.0 15.4 2 7.7 15.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 GAM20675.1 - 2.7 6.3 17.6 3.2 6.1 17.6 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop53 PF07767.11 GAM20675.1 - 4.4 6.6 7.9 5.6 6.3 7.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Dicty_REP PF05086.12 GAM20675.1 - 4.5 5.1 10.8 5.2 4.9 10.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2076 PF09849.9 GAM20675.1 - 8.3 6.4 21.0 9.6 6.2 21.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FNIP PF05725.12 GAM20677.1 - 2.1e-69 229.5 6.9 2.2e-10 40.5 0.3 7.5 5 2 3 8 8 8 8 FNIP Repeat RPN13_C PF16550.5 GAM20677.1 - 0.38 11.0 5.8 5.5 7.2 0.1 4.4 3 1 2 6 6 6 0 UCH-binding domain Biopterin_H PF00351.21 GAM20678.1 - 5.2e-168 558.2 0.0 6.3e-168 558.0 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 GAM20678.1 - 0.00038 20.2 0.0 0.00089 19.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 GAM20678.1 - 0.052 14.1 0.6 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 ACT domain MTCP1 PF08991.10 GAM20679.1 - 3e-05 24.2 4.2 3e-05 24.2 4.2 1.9 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 GAM20679.1 - 0.054 13.7 1.6 0.054 13.7 1.6 2.1 2 0 0 2 2 2 0 CHCH domain JTB PF05439.12 GAM20679.1 - 0.37 10.8 7.3 0.62 10.1 7.3 1.4 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) TFIIS_C PF01096.18 GAM20680.1 - 1.9e-10 40.4 7.3 4.3e-10 39.3 2.5 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.6 GAM20680.1 - 0.00061 20.1 4.1 0.0028 18.0 2.3 2.1 2 0 0 2 2 2 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 GAM20680.1 - 0.004 16.6 2.4 0.004 16.6 2.4 2.8 2 1 1 3 3 3 1 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 GAM20680.1 - 0.24 11.4 8.6 2.8 8.0 5.8 2.9 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Ribosomal_L44 PF00935.19 GAM20680.1 - 0.43 11.1 3.1 9.3 6.8 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L44 DUF4379 PF14311.6 GAM20680.1 - 0.78 10.1 4.5 27 5.2 0.8 2.9 3 0 0 3 3 3 0 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 GAM20680.1 - 0.98 9.6 7.7 3.2 7.9 0.0 3.2 3 0 0 3 3 3 0 Zinc ribbon domain CBFD_NFYB_HMF PF00808.23 GAM20681.1 - 1.7e-07 31.4 0.0 3.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM20681.1 - 0.0017 18.7 4.2 0.0028 18.0 0.0 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.13 GAM20681.1 - 0.0065 16.5 16.5 0.0076 16.3 16.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 GAM20681.1 - 0.21 11.6 3.6 0.24 11.5 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NOA36 PF06524.12 GAM20681.1 - 0.32 10.3 7.6 0.41 9.9 7.6 1.2 1 0 0 1 1 1 0 NOA36 protein FYDLN_acid PF09538.10 GAM20681.1 - 0.33 11.7 5.7 0.64 10.7 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Band_3_cyto PF07565.13 GAM20681.1 - 0.93 9.2 7.1 1.2 8.8 7.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4834 PF16118.5 GAM20681.1 - 0.98 10.4 13.6 2.2 9.3 13.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 GAM20681.1 - 1.4 7.7 16.8 1.9 7.3 16.8 1.2 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 GAM20681.1 - 5.9 5.6 9.6 6.4 5.4 9.6 1.1 1 0 0 1 1 1 0 Presenilin NUSAP PF16006.5 GAM20684.1 - 0.0001 22.2 3.0 0.0001 22.2 3.0 5.0 2 2 2 4 4 4 2 Nucleolar and spindle-associated protein RhoGAP PF00620.27 GAM20685.1 - 5.4e-36 123.7 1.1 1.2e-35 122.6 0.1 2.1 2 0 0 2 2 2 1 RhoGAP domain RhoGEF PF00621.20 GAM20685.1 - 2.9e-28 99.3 1.0 2.9e-28 99.3 1.0 2.9 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 GAM20685.1 - 4e-23 81.9 2.8 9.7e-19 67.8 1.4 2.5 2 0 0 2 2 2 2 PH domain BAR_3 PF16746.5 GAM20685.1 - 6.7e-07 29.3 9.6 3.1e-06 27.1 8.3 2.4 2 0 0 2 2 2 1 BAR domain of APPL family PH_16 PF17838.1 GAM20685.1 - 0.00068 19.5 0.0 0.0039 17.0 0.0 2.3 2 1 0 2 2 2 1 PH domain PH_11 PF15413.6 GAM20685.1 - 0.0012 19.3 6.1 0.0078 16.6 3.6 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain IMD PF08397.11 GAM20685.1 - 0.0015 17.9 1.8 0.0015 17.9 1.8 2.2 1 1 1 2 2 2 1 IRSp53/MIM homology domain PH_10 PF15411.6 GAM20685.1 - 0.0033 17.7 0.2 0.039 14.2 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 GAM20685.1 - 0.1 12.9 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain DivIVA PF05103.13 GAM20685.1 - 0.16 12.0 2.0 18 5.4 0.6 3.0 2 0 0 2 2 2 0 DivIVA protein DUF1664 PF07889.12 GAM20685.1 - 2.9 8.0 5.4 0.86 9.6 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) P4Ha_N PF08336.11 GAM20685.1 - 3 7.8 6.0 25 4.9 1.0 2.9 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HD_4 PF13328.6 GAM20687.1 - 0.0069 16.1 1.7 0.0069 16.1 1.7 2.1 1 1 1 2 2 2 1 HD domain AAA_25 PF13481.6 GAM20688.1 - 1.1e-22 80.6 0.0 2.8e-22 79.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 GAM20688.1 - 1.3e-11 44.3 0.0 2.3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Toprim_2 PF13155.6 GAM20688.1 - 8.9e-08 32.5 0.0 2.5e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Toprim-like AAA_22 PF13401.6 GAM20688.1 - 7.4e-06 26.3 0.2 3e-05 24.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain Toprim_3 PF13362.6 GAM20688.1 - 1.3e-05 25.5 0.0 9.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Toprim domain Toprim_4 PF13662.6 GAM20688.1 - 3e-05 24.4 0.0 0.00033 21.1 0.0 2.5 2 0 0 2 2 2 1 Toprim domain ATPase PF06745.13 GAM20688.1 - 0.00036 19.9 0.1 0.00068 19.1 0.1 1.3 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.6 GAM20688.1 - 0.00079 19.8 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM20688.1 - 0.0042 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 GAM20688.1 - 0.0099 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 GAM20688.1 - 0.014 15.9 0.0 0.039 14.5 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 GAM20688.1 - 0.027 14.2 1.2 0.21 11.3 0.2 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM20688.1 - 0.092 13.2 1.7 0.14 12.6 0.2 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAM20688.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Toprim PF01751.22 GAM20688.1 - 0.1 12.9 0.1 0.81 10.0 0.0 2.5 2 1 0 2 2 2 0 Toprim domain NACHT PF05729.12 GAM20688.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 GAM20688.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TFIIF_alpha PF05793.12 GAM20688.1 - 5.2 5.5 10.6 9.6 4.7 10.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Y_phosphatase PF00102.27 GAM20689.1 - 7.6e-75 251.5 0.3 1e-74 251.0 0.3 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 GAM20689.1 - 2.8e-07 30.4 0.2 1.1e-06 28.5 0.0 2.2 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAM20689.1 - 1.1e-05 25.5 0.0 0.00012 22.2 0.0 2.3 1 1 1 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 GAM20689.1 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Gemini_C4 PF01492.17 GAM20689.1 - 0.15 12.0 3.0 0.57 10.1 2.3 2.1 2 0 0 2 2 2 0 Geminivirus C4 protein PSS PF03034.15 GAM20690.1 - 3.2e-112 374.7 10.5 5.3e-112 374.0 10.5 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF5518 PF17647.1 GAM20690.1 - 0.03 14.5 0.9 0.03 14.5 0.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5518) DUF962 PF06127.11 GAM20690.1 - 0.03 14.4 1.2 2.3 8.4 2.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF962) EMC3_TMCO1 PF01956.16 GAM20690.1 - 0.057 13.1 0.1 0.057 13.1 0.1 1.8 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like CFIA_Pcf11 PF11526.8 GAM20691.1 - 0.0096 16.4 0.2 0.0096 16.4 0.2 2.0 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 zf-C2H2_4 PF13894.6 GAM20691.1 - 0.014 16.2 4.7 0.18 12.7 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAM20691.1 - 0.063 13.6 0.6 0.063 13.6 0.6 2.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) MurB_C PF02873.16 GAM20691.1 - 0.16 12.0 0.1 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Zn-C2H2_12 PF18112.1 GAM20691.1 - 0.2 12.2 0.8 3.4 8.2 0.2 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_3 PF13920.6 GAM20691.1 - 0.27 11.1 1.3 1.3 8.9 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_2 PF13465.6 GAM20691.1 - 9.3 6.9 6.4 17 6.1 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain CTD_bind PF04818.13 GAM20692.1 - 7.4e-05 23.5 0.0 0.00017 22.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.19 GAM20692.1 - 0.0037 17.1 0.1 0.0082 16.0 0.0 1.6 1 1 0 1 1 1 1 VHS domain TFIIA PF03153.13 GAM20692.1 - 5.5 6.9 27.7 7.9 6.4 27.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 GAM20692.1 - 6.2 5.0 22.9 7.3 4.7 22.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TruD PF01142.18 GAM20693.1 - 4.6e-71 239.8 0.1 6.5e-66 222.9 0.2 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) bZIP_1 PF00170.21 GAM20694.1 - 1.8e-12 47.1 10.7 1.8e-12 47.1 10.7 2.5 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 GAM20694.1 - 1.1e-08 35.0 8.6 1.1e-08 35.0 8.6 3.5 3 1 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAM20694.1 - 0.00017 22.1 8.5 0.00017 22.1 8.5 2.8 3 0 0 3 3 3 1 bZIP Maf transcription factor ChaC PF04752.12 GAM20695.1 - 5.3e-53 179.7 0.0 7.2e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein PUA PF01472.20 GAM20695.1 - 6.9e-18 64.4 0.1 1.3e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 PUA domain SET PF00856.28 GAM20696.1 - 2e-15 57.6 0.8 3.6e-15 56.8 0.8 1.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 GAM20696.1 - 0.013 15.6 9.9 0.013 15.6 9.9 2.8 3 1 0 3 3 3 0 MYND finger CEBP_ZZ PF16366.5 GAM20696.1 - 2.8 8.2 17.3 0.08 13.2 6.5 2.7 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain TGT PF01702.18 GAM20697.1 - 3.7e-74 250.0 0.2 4.4e-74 249.7 0.2 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Tyr-DNA_phospho PF06087.12 GAM20697.1 - 0.0077 15.2 0.6 0.015 14.2 0.6 1.4 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase TIP120 PF08623.10 GAM20698.1 - 8.4e-54 181.8 9.8 2.9e-50 170.3 0.0 5.3 5 1 1 6 6 6 2 TATA-binding protein interacting (TIP20) HEAT PF02985.22 GAM20698.1 - 2.8e-16 58.2 9.1 0.47 10.8 0.0 11.4 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.6 GAM20698.1 - 1.9e-13 50.6 5.8 0.0019 18.6 0.0 8.2 7 3 1 8 8 8 3 HEAT repeats Cnd1 PF12717.7 GAM20698.1 - 7.8e-12 45.5 26.2 0.15 12.1 0.0 9.1 6 4 3 9 9 9 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAM20698.1 - 2.6e-08 34.2 4.9 4.6 7.9 0.0 9.8 10 2 2 12 12 12 1 HEAT-like repeat Arm PF00514.23 GAM20698.1 - 0.00026 20.9 5.6 3.4 7.9 0.0 5.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 GAM20698.1 - 0.00044 20.2 4.0 0.12 12.2 0.0 5.6 7 1 0 7 7 7 1 Domain of unknown function (DUF3385) UME PF08064.13 GAM20698.1 - 0.00045 20.1 5.4 15 5.6 0.0 7.2 5 2 3 9 9 9 0 UME (NUC010) domain RIX1 PF08167.12 GAM20698.1 - 0.00098 18.9 30.0 0.076 12.8 2.4 7.8 6 3 1 8 8 8 2 rRNA processing/ribosome biogenesis V-ATPase_H_C PF11698.8 GAM20698.1 - 0.029 14.5 4.8 41 4.3 0.1 6.4 7 0 0 7 7 7 0 V-ATPase subunit H SDA1 PF05285.12 GAM20698.1 - 0.055 12.9 2.1 0.081 12.3 2.1 1.2 1 0 0 1 1 1 0 SDA1 E1_UFD PF09358.10 GAM20698.1 - 0.08 13.6 1.0 0.32 11.7 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin fold domain Sigma70_ner PF04546.13 GAM20698.1 - 0.93 9.3 7.0 2.8 7.8 7.0 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region Prp18 PF02840.15 GAM20699.1 - 1e-60 203.9 0.4 1e-60 203.9 0.4 2.7 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.11 GAM20699.1 - 4.8e-10 38.8 2.3 1.4e-09 37.4 2.3 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like PTPA PF03095.15 GAM20699.1 - 0.052 13.0 1.9 0.068 12.6 0.5 1.9 1 1 1 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein Aldo_ket_red PF00248.21 GAM20700.1 - 8.5e-49 166.3 0.0 1e-48 166.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family COX7a PF02238.15 GAM20701.1 - 1.9 8.9 4.2 35 4.9 0.3 3.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII LapA_dom PF06305.11 GAM20702.1 - 0.14 12.0 0.0 0.14 12.0 0.0 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain ARID PF01388.21 GAM20703.1 - 2.4e-13 50.5 0.1 5.5e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SR-25 PF10500.9 GAM20703.1 - 1.1 8.9 23.8 0.11 12.1 18.5 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein LAT PF15234.6 GAM20703.1 - 3.2 7.4 11.9 11 5.7 11.9 1.9 1 1 0 1 1 1 0 Linker for activation of T-cells SH2_2 PF14633.6 GAM20704.1 - 2.5e-61 206.8 2.7 3.2e-61 206.5 1.3 2.0 2 0 0 2 2 1 1 SH2 domain AAA PF00004.29 GAM20704.1 - 1e-48 165.1 0.0 9.8e-31 106.9 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM20704.1 - 1.4e-23 82.5 0.6 7.4e-12 44.9 0.1 3.0 2 0 0 2 2 2 2 AAA+ lid domain HHH_7 PF14635.6 GAM20704.1 - 2.6e-20 72.7 0.3 6.7e-20 71.4 0.3 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 GAM20704.1 - 7.2e-20 71.3 0.0 2e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 GAM20704.1 - 4.9e-15 56.0 3.2 1.5e-14 54.4 3.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 AAA_16 PF13191.6 GAM20704.1 - 1.7e-10 41.5 0.7 2.9e-05 24.5 0.1 4.6 3 1 1 4 4 4 2 AAA ATPase domain SH2 PF00017.24 GAM20704.1 - 8e-07 29.1 0.0 0.002 18.2 0.0 2.9 2 0 0 2 2 2 2 SH2 domain AAA_22 PF13401.6 GAM20704.1 - 2.3e-06 27.9 0.0 0.17 12.1 0.0 3.7 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 GAM20704.1 - 6.1e-06 25.8 0.0 0.0034 16.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI HHH_9 PF17674.1 GAM20704.1 - 4.7e-05 24.2 0.8 0.0005 20.9 0.8 2.9 1 1 0 1 1 1 1 HHH domain Sigma54_activat PF00158.26 GAM20704.1 - 9.6e-05 22.1 0.0 0.7 9.6 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 GAM20704.1 - 0.0012 18.4 0.0 0.42 10.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 GAM20704.1 - 0.0021 17.3 0.0 0.054 12.7 0.0 2.7 3 0 0 3 3 3 1 TIP49 P-loop domain DUF815 PF05673.13 GAM20704.1 - 0.0022 17.2 0.0 0.7 9.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 GAM20704.1 - 0.003 18.1 5.9 1.2 9.7 0.0 3.9 3 0 0 3 3 2 2 ABC transporter AAA_5 PF07728.14 GAM20704.1 - 0.0037 17.3 0.0 0.96 9.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Tex_N PF09371.10 GAM20704.1 - 0.0064 16.2 0.0 3.3 7.3 0.1 2.5 2 0 0 2 2 2 1 Tex-like protein N-terminal domain RuvB_N PF05496.12 GAM20704.1 - 0.0072 16.1 0.0 0.27 11.0 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 GAM20704.1 - 0.011 16.2 0.0 4.4 7.7 0.0 3.5 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 GAM20704.1 - 0.021 14.1 0.0 4.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin TniB PF05621.11 GAM20704.1 - 0.029 13.8 0.0 6.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 GAM20704.1 - 0.031 14.4 0.7 1.9 8.6 0.0 3.4 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 GAM20704.1 - 0.034 14.0 0.4 4.4 7.2 0.1 3.7 3 2 0 4 4 4 0 NACHT domain IstB_IS21 PF01695.17 GAM20704.1 - 0.047 13.4 0.0 0.41 10.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 GAM20704.1 - 0.06 13.5 0.0 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 GAM20704.1 - 0.077 12.7 0.1 16 5.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain LRR_4 PF12799.7 GAM20705.1 - 1.1e-26 92.4 41.4 9.1e-07 29.1 3.6 7.4 5 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM20705.1 - 2.1e-22 78.6 44.2 6.1e-08 32.3 0.7 6.9 2 2 5 7 7 7 7 Leucine rich repeat LRR_1 PF00560.33 GAM20705.1 - 1.5e-13 49.3 34.2 0.3 11.8 0.0 11.7 11 0 0 11 11 11 5 Leucine Rich Repeat Filamin PF00630.19 GAM20705.1 - 1.2e-09 38.9 0.1 1.8e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat LRR_6 PF13516.6 GAM20705.1 - 0.00017 21.4 47.3 0.85 9.8 0.1 10.3 10 0 0 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.6 GAM20705.1 - 0.18 11.3 13.2 2.4 7.6 0.9 3.7 1 1 4 5 5 5 0 Leucine-rich repeat Abhydrolase_6 PF12697.7 GAM20707.1 - 1.1e-17 65.3 0.0 1.5e-17 64.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 GAM20707.1 - 3.3e-06 27.0 0.1 5.4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM20707.1 - 0.00014 21.2 0.8 0.0028 17.0 0.8 2.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GAM20707.1 - 0.00027 20.9 0.1 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_1 PF00561.20 GAM20707.1 - 0.003 17.3 2.9 0.035 13.8 1.4 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold CW_7 PF08230.11 GAM20707.1 - 0.09 12.5 0.5 0.32 10.8 0.5 2.0 1 1 0 1 1 1 0 CW_7 repeat FliH PF02108.16 GAM20708.1 - 0.019 15.0 0.8 0.71 9.9 0.1 3.5 3 0 0 3 3 3 0 Flagellar assembly protein FliH Sod_Ni PF09055.11 GAM20708.1 - 0.045 14.3 4.1 0.17 12.5 1.2 2.8 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase Peptidase_C50 PF03568.17 GAM20709.1 - 1.5e-74 251.5 0.0 1.5e-74 251.5 0.0 2.8 3 0 0 3 3 3 1 Peptidase family C50 CHAT PF12770.7 GAM20709.1 - 8.8e-06 25.3 0.0 0.0001 21.8 0.0 2.4 2 0 0 2 2 2 1 CHAT domain TPR_2 PF07719.17 GAM20709.1 - 9.7e-06 25.3 8.0 0.57 10.4 0.2 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM20709.1 - 7.7e-05 22.9 9.1 0.13 12.5 0.1 6.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM20709.1 - 0.00057 19.9 10.2 2.8 8.4 0.0 7.8 9 0 0 9 9 7 1 Tetratricopeptide repeat RPN7 PF10602.9 GAM20709.1 - 0.00071 19.3 0.8 0.21 11.3 0.1 4.3 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_14 PF13428.6 GAM20709.1 - 0.033 15.0 1.0 25 6.0 0.1 5.3 5 0 0 5 5 3 0 Tetratricopeptide repeat CCDC24 PF15669.5 GAM20709.1 - 0.05 13.5 12.7 0.026 14.4 4.6 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 24 family TPR_7 PF13176.6 GAM20709.1 - 0.11 12.6 7.9 15 5.9 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM20709.1 - 0.11 13.1 8.3 5.8 7.8 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM20709.1 - 0.12 12.3 0.0 1.3 9.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Pol_alpha_B_N PF08418.10 GAM20709.1 - 0.88 9.5 9.1 2.2 8.2 2.5 2.5 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal AF-4 PF05110.13 GAM20709.1 - 2.6 6.0 21.2 5.4 5.0 21.2 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Secretin_N_2 PF07655.13 GAM20709.1 - 4.4 7.9 24.9 0.32 11.6 19.2 2.1 2 0 0 2 2 1 0 Secretin N-terminal domain RVT_1 PF00078.27 GAM20710.1 - 2.1e-34 119.0 0.0 3.1e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 GAM20711.1 - 1.9e-12 47.5 1.6 0.0034 18.2 0.2 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat CAP_C PF08603.11 GAM20713.1 - 5e-07 29.5 1.0 8.8e-07 28.7 1.0 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal SEC-C PF02810.15 GAM20713.1 - 1.5e-05 24.8 12.6 2.8e-05 23.9 12.6 1.4 1 0 0 1 1 1 1 SEC-C motif LD_cluster3 PF18180.1 GAM20713.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 SLOG cluster3 family Peptidase_S28 PF05577.12 GAM20714.1 - 3e-79 266.8 0.2 3.6e-79 266.6 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 GAM20714.1 - 1.3e-07 31.6 0.0 2e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 GAM20714.1 - 4.6e-07 28.9 0.0 8e-06 24.8 0.0 2.0 2 0 0 2 2 2 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 GAM20714.1 - 0.002 17.4 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM20714.1 - 0.0029 17.1 0.0 0.032 13.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family WD40 PF00400.32 GAM20715.1 - 2.7e-39 132.4 23.1 0.00064 20.5 0.0 11.4 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM20715.1 - 6.7e-14 52.0 3.8 0.0088 16.3 0.0 6.9 3 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM20715.1 - 1.6e-08 34.7 0.5 0.0034 17.3 0.1 5.0 2 1 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM20715.1 - 0.00054 19.0 1.6 11 4.8 0.0 5.0 5 1 1 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NUP214 PF16755.5 GAM20715.1 - 0.0091 15.3 0.0 0.019 14.2 0.0 1.4 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 PD40 PF07676.12 GAM20715.1 - 0.012 15.6 0.3 2.7 8.0 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 GAM20715.1 - 0.014 14.1 7.2 0.89 8.1 0.1 3.9 4 1 0 4 4 4 0 Nucleoporin Nup120/160 COPI_assoc PF08507.10 GAM20716.1 - 7.3e-20 71.3 18.5 8.6e-20 71.1 18.5 1.0 1 0 0 1 1 1 1 COPI associated protein FBPase PF00316.20 GAM20717.1 - 9.1e-61 204.6 0.2 1.3e-60 204.2 0.2 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 GAM20717.1 - 0.02 14.4 0.0 0.13 11.8 0.0 2.1 3 0 0 3 3 3 0 Inositol monophosphatase family YqaH PF17448.2 GAM20717.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized YqaH-like LptF_LptG PF03739.14 GAM20718.1 - 0.067 12.0 0.1 0.1 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG SKG6 PF08693.10 GAM20718.1 - 0.19 11.1 3.7 0.45 10.0 3.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF_2 PF07974.13 GAM20718.1 - 0.26 11.7 15.1 0.77 10.2 15.1 1.9 1 0 0 1 1 1 0 EGF-like domain EB PF01683.18 GAM20718.1 - 0.42 10.9 7.4 0.29 11.5 5.0 1.9 2 0 0 2 2 2 0 EB module Bacteriocin_II PF01721.18 GAM20719.1 - 0.00033 20.7 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 Class II bacteriocin Acyl_transf_3 PF01757.22 GAM20720.1 - 4.4e-30 104.9 40.5 7.2e-30 104.2 40.5 1.3 1 0 0 1 1 1 1 Acyltransferase family CH PF00307.31 GAM20722.1 - 4.1e-15 55.9 0.2 9.2e-15 54.8 0.2 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain SR-25 PF10500.9 GAM20722.1 - 0.0081 15.8 1.6 0.0081 15.8 1.6 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.11 GAM20722.1 - 0.64 8.0 15.0 0.19 9.8 12.2 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF3439 PF11921.8 GAM20722.1 - 8.9 6.3 14.0 7.6 6.5 6.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Cofilin_ADF PF00241.20 GAM20723.1 - 2.9e-14 52.9 0.0 1.3e-13 50.8 0.0 2.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein LIM PF00412.22 GAM20723.1 - 1e-11 44.9 8.6 2.2e-11 43.8 8.6 1.6 1 0 0 1 1 1 1 LIM domain Baculo_PEP_C PF04513.12 GAM20723.1 - 0.032 14.3 46.9 0.14 12.2 7.2 6.4 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C3HC4_2 PF13923.6 GAM20723.1 - 4.1 7.3 4.9 21 5.1 2.2 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 GAM20724.1 - 1.4e-64 218.0 0.0 5e-63 212.9 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20724.1 - 7.4e-29 100.8 0.2 1e-19 70.8 0.1 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAM20724.1 - 4.9e-05 22.8 0.0 0.31 10.3 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 GAM20724.1 - 0.0014 17.7 0.0 0.0014 17.7 0.0 2.3 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 GAM20724.1 - 0.012 14.9 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM20724.1 - 0.013 15.4 0.1 0.094 12.6 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM20724.1 - 0.05 13.2 0.0 0.05 13.2 0.0 2.1 3 0 0 3 3 3 0 Choline/ethanolamine kinase eIF-4B PF06273.11 GAM20724.1 - 0.11 11.6 1.7 0.2 10.7 1.7 1.4 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Cation_efflux PF01545.21 GAM20725.1 - 4.3e-27 95.1 10.8 5.7e-27 94.8 10.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAM20725.1 - 9.5e-12 44.9 0.0 1.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4271 PF14093.6 GAM20725.1 - 0.57 10.1 5.6 0.87 9.5 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Myb_DNA-binding PF00249.31 GAM20726.1 - 6.8e-10 39.0 0.1 1.2e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SUIM_assoc PF16619.5 GAM20726.1 - 0.069 13.2 23.2 0.6 10.2 2.9 4.1 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Myb_DNA-bind_7 PF15963.5 GAM20726.1 - 0.071 13.0 0.5 0.071 13.0 0.5 2.0 2 0 0 2 2 2 0 Myb DNA-binding like Clathrin_H_link PF13838.6 GAM20726.1 - 0.53 10.2 11.9 2 8.4 6.0 2.8 2 0 0 2 2 2 0 Clathrin-H-link DUF702 PF05142.12 GAM20726.1 - 8 6.9 16.5 1.3 9.5 3.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF702) Acyltransferase PF01553.21 GAM20727.1 - 6.4e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MpPF26 PF07666.11 GAM20727.1 - 5.6 7.1 12.4 9.7 6.3 12.4 1.3 1 0 0 1 1 1 0 M penetrans paralogue family 26 DUF2208 PF09973.9 GAM20727.1 - 6.2 6.4 9.0 9.8 5.7 9.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) YtzH PF14165.6 GAM20728.1 - 0.0036 17.7 9.1 0.063 13.7 0.1 3.8 3 1 1 4 4 4 2 YtzH-like protein Tropomyosin_1 PF12718.7 GAM20728.1 - 0.012 15.8 3.4 0.012 15.8 3.4 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF2430 PF10353.9 GAM20728.1 - 0.13 12.7 0.1 0.42 11.0 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2430) TetR_C_24 PF17932.1 GAM20728.1 - 0.17 12.2 0.7 0.35 11.1 0.7 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Hemerythrin PF01814.23 GAM20729.1 - 5.7e-09 36.7 12.1 2.9e-08 34.4 4.8 1.7 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain ABA_GPCR PF12430.8 GAM20729.1 - 0.031 14.1 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor DUF3825 PF12873.7 GAM20729.1 - 0.044 13.2 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) FUSC PF04632.12 GAM20729.1 - 0.12 10.9 1.2 0.14 10.6 1.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SWIM PF04434.17 GAM20730.1 - 0.039 13.6 0.3 0.084 12.6 0.3 1.5 1 0 0 1 1 1 0 SWIM zinc finger Glft2_N PF17994.1 GAM20730.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Galactofuranosyltransferase 2 N-terminal Abhydrolase_3 PF07859.13 GAM20731.1 - 2.3e-66 223.7 0.1 2.3e-66 223.7 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold FYVE PF01363.21 GAM20731.1 - 2e-20 72.7 11.9 2e-20 72.7 11.9 2.2 3 0 0 3 3 2 1 FYVE zinc finger COesterase PF00135.28 GAM20731.1 - 4.6e-12 45.6 3.4 1.4e-11 44.0 0.0 2.6 2 1 0 2 2 2 1 Carboxylesterase family DUF4647 PF15504.6 GAM20731.1 - 0.0012 18.1 4.5 0.0015 17.7 4.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) XAP5 PF04921.14 GAM20731.1 - 0.0013 18.6 1.7 0.0019 18.0 1.7 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator Peptidase_S9 PF00326.21 GAM20731.1 - 0.0039 16.7 1.9 0.015 14.8 0.1 2.5 2 1 0 2 2 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 GAM20731.1 - 0.0048 15.8 2.2 0.006 15.5 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase AXE1 PF05448.12 GAM20731.1 - 0.029 13.1 0.0 0.085 11.5 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 GAM20731.1 - 0.041 12.8 0.0 0.075 11.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Spt20 PF12090.8 GAM20731.1 - 0.12 12.0 24.7 0.21 11.2 24.7 1.3 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 GAM20731.1 - 0.14 10.9 8.1 0.17 10.6 8.1 1.1 1 0 0 1 1 1 0 Presenilin zf-RING_UBOX PF13445.6 GAM20731.1 - 0.23 11.5 7.7 0.74 9.9 7.7 2.0 1 1 0 1 1 1 0 RING-type zinc-finger TFIIA PF03153.13 GAM20731.1 - 0.35 10.8 17.9 0.47 10.4 17.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PhnA_Zn_Ribbon PF08274.12 GAM20731.1 - 0.49 10.4 5.0 1.9 8.5 5.0 2.0 1 1 0 1 1 1 0 PhnA Zinc-Ribbon SLC12 PF03522.15 GAM20731.1 - 0.99 8.4 7.6 1.3 8.0 7.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 zf-TFIIIC PF12660.7 GAM20731.1 - 1.4 8.9 9.1 0.092 12.7 3.3 2.0 2 0 0 2 2 1 0 Putative zinc-finger of transcription factor IIIC complex Zip PF02535.22 GAM20731.1 - 1.7 7.8 4.1 2.6 7.2 4.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1387 PF07139.11 GAM20731.1 - 2.5 7.8 15.0 3.4 7.3 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Androgen_recep PF02166.16 GAM20731.1 - 2.5 6.9 11.8 4.3 6.1 11.8 1.3 1 0 0 1 1 1 0 Androgen receptor Ndc1_Nup PF09531.10 GAM20731.1 - 2.8 6.5 8.9 3.6 6.2 8.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TERB2 PF15101.6 GAM20731.1 - 4.5 7.3 13.6 7.8 6.5 13.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 zf-RING_5 PF14634.6 GAM20731.1 - 9.1 6.3 17.5 67 3.6 17.7 2.2 1 1 1 2 2 2 0 zinc-RING finger domain ArfGap PF01412.18 GAM20732.1 - 2.1e-37 127.8 0.0 3.2e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 GAM20732.1 - 2.6e-19 69.7 0.5 4.5e-19 68.9 0.5 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM20732.1 - 2.5e-06 27.8 2.6 1.2e-05 25.7 1.5 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 GAM20732.1 - 7.9e-05 22.7 0.1 0.00014 21.9 0.1 1.4 1 0 0 1 1 1 1 PH domain MFS_1 PF07690.16 GAM20733.1 - 6.4e-38 130.6 47.4 6.5e-26 91.1 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM20733.1 - 6.1e-10 38.5 27.4 4.8e-09 35.6 10.9 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter CbtA PF09490.10 GAM20733.1 - 0.2 11.4 7.5 1.7 8.4 0.0 4.0 5 0 0 5 5 5 0 Probable cobalt transporter subunit (CbtA) MFS_1 PF07690.16 GAM20734.1 - 1.3e-30 106.5 28.5 5.6e-25 88.0 14.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 GAM20735.1 - 2.8e-08 34.3 13.6 0.0019 19.0 0.5 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM20735.1 - 1.7e-05 25.0 4.6 0.49 10.7 0.1 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain NHL PF01436.21 GAM20735.1 - 0.0057 16.6 0.2 4.3 7.6 0.1 3.0 2 0 0 2 2 2 2 NHL repeat NUC153 PF08159.12 GAM20736.1 - 1.2e-06 28.2 3.4 2.6e-06 27.1 3.4 1.6 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 GAM20736.1 - 0.027 14.8 0.0 0.19 12.0 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Kinase-PPPase PF03618.14 GAM20736.1 - 0.035 13.9 0.4 0.17 11.7 0.6 1.9 2 0 0 2 2 2 0 Kinase/pyrophosphorylase Glyco_tran_WecB PF03808.13 GAM20736.1 - 0.16 11.9 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF2951 PF11166.8 GAM20736.1 - 2.1 8.6 7.1 0.61 10.3 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Kri1_C PF12936.7 GAM20737.1 - 2.8e-23 81.9 2.2 2.8e-23 81.9 2.2 4.5 5 0 0 5 5 5 1 KRI1-like family C-terminal RabGAP-TBC PF00566.18 GAM20738.1 - 3.5e-24 85.7 0.3 5.5e-24 85.0 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-B_box PF00643.24 GAM20738.1 - 8.4e-06 25.9 4.6 1.9e-05 24.7 4.6 1.6 1 0 0 1 1 1 1 B-box zinc finger FYVE PF01363.21 GAM20738.1 - 0.009 16.1 1.4 0.02 15.0 1.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4_4 PF15227.6 GAM20738.1 - 0.014 15.5 3.9 0.014 15.5 3.9 2.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAM20738.1 - 0.028 14.3 5.0 0.07 13.0 5.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM20738.1 - 0.24 11.4 4.0 0.68 9.9 4.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAM20738.1 - 3.3 7.6 12.0 0.034 14.0 4.3 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YL1 PF05764.13 GAM20739.1 - 0.13 12.3 15.7 0.078 13.1 12.7 2.0 2 0 0 2 2 2 0 YL1 nuclear protein DUF3439 PF11921.8 GAM20739.1 - 5.3 7.0 16.2 53 3.8 10.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Crystall_3 PF08964.10 GAM20740.1 - 0.005 17.0 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall PF00030.19 GAM20740.1 - 0.057 13.6 0.0 0.16 12.2 0.0 1.9 1 1 0 1 1 1 0 Beta/Gamma crystallin ABC2_membrane_3 PF12698.7 GAM20741.1 - 5.8e-29 101.3 30.4 5.8e-29 101.3 30.4 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 GAM20741.1 - 2.9e-26 92.6 0.0 6.2e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM20741.1 - 9e-12 45.4 0.2 1.1e-06 28.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 GAM20741.1 - 0.00018 21.0 26.9 0.00018 21.0 26.9 2.4 3 0 0 3 3 2 1 ABC-2 type transporter AAA_23 PF13476.6 GAM20741.1 - 0.00036 21.1 0.3 0.00092 19.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain SMC_N PF02463.19 GAM20741.1 - 0.0014 18.1 0.3 0.83 9.0 0.0 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAM20741.1 - 0.0021 17.8 0.0 0.099 12.3 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 GAM20741.1 - 0.003 17.5 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 GAM20741.1 - 0.0047 16.7 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_27 PF13514.6 GAM20741.1 - 0.049 13.2 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAM20741.1 - 0.069 12.9 0.1 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAM20741.1 - 0.099 12.4 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 GAM20741.1 - 0.19 12.1 0.9 15 6.0 0.2 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_2 PF12679.7 GAM20741.1 - 2.3 7.4 16.3 0.7 9.1 12.9 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4271 PF14093.6 GAM20741.1 - 4.9 7.0 38.8 0.43 10.5 33.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF4449 PF14613.6 GAM20742.1 - 4.6e-06 26.8 1.4 4.6e-06 26.8 1.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.25 GAM20742.1 - 0.001 18.7 0.2 0.0035 17.0 0.2 2.0 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain PHA_gran_rgn PF09650.10 GAM20742.1 - 0.1 12.9 0.7 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Op_neuropeptide PF08035.11 GAM20742.1 - 0.13 12.2 0.7 0.83 9.6 0.3 2.4 2 0 0 2 2 2 0 Opioids neuropeptide Ank_4 PF13637.6 GAM20744.1 - 5.6e-12 45.9 3.1 0.00047 20.7 0.8 5.2 1 1 4 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM20744.1 - 1e-11 45.3 3.2 0.00066 20.2 1.2 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM20744.1 - 7.3e-08 32.5 4.1 0.0079 16.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20744.1 - 1.5e-06 28.1 0.3 0.12 13.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAM20744.1 - 0.00067 20.0 0.2 0.36 11.4 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat CTC1_2 PF15491.6 GAM20744.1 - 0.011 15.0 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 TetR_C_23 PF17931.1 GAM20744.1 - 0.4 10.8 2.1 7 6.8 0.2 3.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SelP_N PF04592.14 GAM20744.1 - 3.2 7.1 18.2 0.32 10.3 12.6 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region CLP1_P PF16575.5 GAM20745.1 - 5.3e-38 130.7 0.0 9.5e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 GAM20745.1 - 0.057 13.5 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 GAM20745.1 - 0.095 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_C48 PF02902.19 GAM20746.1 - 3.4e-21 76.1 0.1 4.8e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Branch PF02485.21 GAM20747.1 - 2.5e-15 56.7 2.4 2.5e-15 56.7 2.4 2.0 2 1 0 2 2 2 1 Core-2/I-Branching enzyme RyR PF02026.16 GAM20747.1 - 0.034 14.3 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 RyR domain BTB PF00651.31 GAM20749.1 - 7e-16 58.4 0.0 1.8e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 GAM20749.1 - 1.3e-05 25.2 0.1 8.8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch MFS_1 PF07690.16 GAM20750.1 - 3.3e-34 118.4 18.2 5.5e-34 117.6 18.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NUDIX PF00293.28 GAM20751.1 - 1e-21 77.4 0.1 1.8e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-RING_UBOX PF13445.6 GAM20752.1 - 1.4e-07 31.4 5.0 1.4e-07 31.4 5.0 4.0 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 GAM20752.1 - 5.5e-05 23.4 6.3 5.5e-05 23.4 6.3 4.2 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 GAM20752.1 - 6e-05 22.8 4.5 6e-05 22.8 4.5 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 GAM20752.1 - 0.00014 22.0 9.6 0.00014 22.0 9.6 4.4 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 GAM20752.1 - 0.0017 18.2 6.1 0.0017 18.2 6.1 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAM20752.1 - 0.0018 18.4 4.7 0.0018 18.4 4.7 4.1 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAM20752.1 - 0.003 17.4 6.3 0.003 17.4 6.3 4.4 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Phi29_Phage_SSB PF17427.2 GAM20752.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Phage Single-stranded DNA-binding protein Phage_TAC_5 PF08890.11 GAM20752.1 - 0.2 11.6 4.1 0.13 12.3 1.5 2.1 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC BRF1 PF07741.13 GAM20752.1 - 0.88 10.0 5.9 0.62 10.4 1.6 2.8 2 1 1 3 3 3 0 Brf1-like TBP-binding domain DUF1664 PF07889.12 GAM20752.1 - 1.2 9.2 3.5 2.8 8.0 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Metallophos PF00149.28 GAM20753.1 - 3.7e-30 106.0 0.6 6.1e-30 105.2 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 GAM20753.1 - 8e-27 93.4 4.7 9e-27 93.2 1.3 2.3 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_2 PF07719.17 GAM20753.1 - 1e-13 50.2 2.6 3.1e-07 30.0 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM20753.1 - 5.3e-13 48.2 5.8 2.5e-07 30.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM20753.1 - 1.5e-09 37.4 1.5 0.0084 15.8 0.1 3.6 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 GAM20753.1 - 5.2e-09 35.6 0.3 1.6e-05 24.8 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM20753.1 - 5.1e-08 33.1 0.6 1.8e-05 25.1 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM20753.1 - 4.4e-07 30.2 0.0 4.7e-05 23.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM20753.1 - 4.9e-07 30.2 0.1 1.2e-05 25.7 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM20753.1 - 0.00014 22.4 0.1 0.051 14.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM20753.1 - 0.00077 19.3 0.1 0.13 12.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM20753.1 - 0.0057 16.9 1.1 0.42 10.9 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 GAM20753.1 - 0.0078 16.3 0.4 1.4 9.0 0.0 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 GAM20753.1 - 0.0086 16.4 0.8 0.44 11.0 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat 3A PF00803.18 GAM20753.1 - 0.055 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family zf-RRN7 PF11781.8 GAM20754.1 - 0.00021 20.9 1.7 0.00044 19.9 1.7 1.6 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Cys_rich_CPCC PF14206.6 GAM20754.1 - 0.1 12.4 0.3 0.23 11.3 0.3 1.6 1 0 0 1 1 1 0 Cysteine-rich CPCC zf-NADH-PPase PF09297.11 GAM20754.1 - 0.11 12.1 0.6 0.2 11.3 0.6 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain HD PF01966.22 GAM20759.1 - 1.3e-07 31.9 0.1 1.7e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 HD domain MIOX PF05153.15 GAM20759.1 - 5e-05 23.0 0.2 7.5e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase HD_4 PF13328.6 GAM20759.1 - 6.9e-05 22.6 2.9 0.00033 20.4 2.9 2.0 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 GAM20759.1 - 0.00011 21.7 0.5 0.00027 20.5 0.2 1.8 2 1 0 2 2 2 1 HDOD domain HD_6 PF18019.1 GAM20759.1 - 0.023 14.8 0.2 0.025 14.7 0.2 1.2 1 0 0 1 1 1 0 HD domain GYF PF02213.16 GAM20759.1 - 0.062 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 GYF domain PhyH PF05721.13 GAM20760.1 - 1.3e-32 113.8 0.0 1.6e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 GAM20760.1 - 0.0046 17.3 0.0 0.0089 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF3592 PF12158.8 GAM20761.1 - 0.0022 18.1 0.2 0.0022 18.1 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3592) ATP-synt_I PF03899.15 GAM20761.1 - 0.27 11.6 9.7 0.94 9.9 2.5 2.2 2 0 0 2 2 2 0 ATP synthase I chain Ank_2 PF12796.7 GAM20762.1 - 1.4e-25 89.7 0.2 6.1e-11 42.8 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20762.1 - 5.7e-19 68.2 0.5 1.8e-07 31.6 0.0 4.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM20762.1 - 2.9e-16 59.1 0.4 0.0033 17.8 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 GAM20762.1 - 3.2e-15 54.7 0.0 0.017 15.6 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 GAM20762.1 - 8.9e-13 48.2 3.0 0.00036 20.8 0.1 5.5 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Otopetrin PF03189.13 GAM20762.1 - 0.21 10.3 0.0 3 6.6 0.0 2.5 1 1 0 1 1 1 0 Otopetrin LRAT PF04970.13 GAM20762.1 - 9.9 6.5 9.0 23 5.3 3.9 3.4 3 1 0 3 3 3 0 Lecithin retinol acyltransferase PH PF00169.29 GAM20763.1 - 8.6e-09 35.9 0.2 6.8e-08 33.0 0.2 2.5 1 1 0 1 1 1 1 PH domain Maelstrom PF13017.6 GAM20763.1 - 0.0017 18.0 0.7 0.034 13.8 0.3 2.4 2 0 0 2 2 2 1 piRNA pathway germ-plasm component PH_4 PF15404.6 GAM20763.1 - 0.003 17.4 7.7 0.2 11.4 0.0 3.3 2 1 1 3 3 3 2 Pleckstrin homology domain CPSF73-100_C PF11718.8 GAM20763.1 - 0.016 14.7 0.2 0.038 13.5 0.2 1.6 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term PH_11 PF15413.6 GAM20763.1 - 0.7 10.3 9.4 0.09 13.2 1.0 3.7 3 1 0 3 3 3 0 Pleckstrin homology domain NOA36 PF06524.12 GAM20763.1 - 2.1 7.6 8.7 0.69 9.2 4.9 2.1 2 0 0 2 2 2 0 NOA36 protein NST1 PF13945.6 GAM20763.1 - 8.9 6.4 16.4 0.051 13.7 4.6 2.9 3 0 0 3 3 3 0 Salt tolerance down-regulator Mago_nashi PF02792.14 GAM20766.1 - 1.1e-68 229.7 0.8 1.4e-68 229.4 0.8 1.1 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.8 GAM20766.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) Tcf25 PF04910.14 GAM20767.1 - 6.1e-85 285.4 0.2 6.1e-85 285.4 0.2 2.0 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Fe_bilin_red PF05996.12 GAM20767.1 - 0.0062 16.3 0.5 0.012 15.3 0.5 1.5 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Methyltransf_21 PF05050.12 GAM20767.1 - 0.054 13.5 0.8 0.13 12.2 0.8 1.6 1 0 0 1 1 1 0 Methyltransferase FkbM domain CDC45 PF02724.14 GAM20767.1 - 0.23 9.7 20.1 0.36 9.1 20.1 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM220 PF15487.6 GAM20767.1 - 0.66 9.6 14.6 1.3 8.6 14.6 1.5 1 0 0 1 1 1 0 FAM220 family YL1 PF05764.13 GAM20767.1 - 2.9 7.9 24.8 0.035 14.2 17.2 1.7 2 0 0 2 2 2 0 YL1 nuclear protein Ndc1_Nup PF09531.10 GAM20767.1 - 6 5.4 12.0 0.078 11.7 4.7 1.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup MtN3_slv PF03083.16 GAM20769.1 - 7.5e-27 93.2 14.3 3.4e-18 65.5 5.0 2.3 2 1 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Orbi_NS3 PF01616.16 GAM20769.1 - 0.18 11.5 0.5 0.27 10.9 0.5 1.2 1 0 0 1 1 1 0 Orbivirus NS3 DUF2085 PF09858.9 GAM20769.1 - 2.2 8.8 8.6 0.36 11.3 2.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) DUF4191 PF13829.6 GAM20769.1 - 7.1 5.9 9.4 2.3 7.5 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Prefoldin PF02996.17 GAM20770.1 - 4.8e-26 91.0 1.7 4.8e-26 91.0 1.7 1.6 1 1 1 2 2 2 1 Prefoldin subunit BST2 PF16716.5 GAM20770.1 - 0.044 14.4 0.8 12 6.6 0.0 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Phenyl_P_gamma PF09662.10 GAM20770.1 - 0.086 13.0 0.8 0.19 11.9 0.1 2.0 2 1 0 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) SIMPL PF04402.14 GAM20770.1 - 0.096 13.1 6.2 0.11 12.9 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF541) Syntaxin-6_N PF09177.11 GAM20770.1 - 0.31 11.6 3.3 1.3 9.6 0.4 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Epimerase PF01370.21 GAM20771.1 - 2e-14 53.7 0.0 2.7e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM20771.1 - 4.9e-07 29.1 0.0 6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 GAM20771.1 - 8.5e-07 28.7 0.0 1.5e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1731 PF08338.11 GAM20771.1 - 0.00011 22.0 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) NAD_binding_4 PF07993.12 GAM20771.1 - 0.0016 17.7 0.0 0.41 9.8 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 GAM20771.1 - 0.012 14.7 0.0 0.038 13.0 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.23 GAM20771.1 - 0.016 15.3 0.1 0.029 14.5 0.0 1.6 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 GAM20771.1 - 0.029 14.3 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 GAM20771.1 - 0.16 11.9 0.0 8.3 6.3 0.0 2.1 1 1 1 2 2 2 0 KR domain DDE_Tnp_4 PF13359.6 GAM20772.1 - 2.2e-23 82.7 0.4 6e-22 78.0 0.4 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM20772.1 - 1.8e-08 34.3 2.1 3e-08 33.6 2.1 1.4 1 1 0 1 1 1 1 Transposase DDE domain zf-MYND PF01753.18 GAM20774.1 - 2.1e-06 27.7 13.7 3.7e-06 26.9 13.7 1.4 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 GAM20774.1 - 0.12 10.2 7.8 0.13 10.1 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 FSA_C PF10479.9 GAM20774.1 - 0.27 9.3 5.7 0.43 8.7 5.7 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF4718 PF15842.5 GAM20774.1 - 0.51 10.1 13.1 0.62 9.8 7.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4718) DUF4711 PF15829.5 GAM20774.1 - 4.4 7.2 12.4 7.1 6.5 12.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4711) ThrE PF06738.12 GAM20775.1 - 8e-64 215.3 22.4 4e-53 180.3 2.7 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAM20775.1 - 3.4e-11 43.4 29.6 1.1e-08 35.2 9.5 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE TruB_C_2 PF16198.5 GAM20775.1 - 0.15 12.3 1.6 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain DUF2572 PF10833.8 GAM20775.1 - 0.79 9.4 6.1 1.8 8.3 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) CASP_C PF08172.12 GAM20775.1 - 0.95 8.8 7.9 0.058 12.7 2.7 1.5 2 0 0 2 2 2 0 CASP C terminal IFRD PF05004.13 GAM20776.1 - 1.3e-18 67.1 21.3 1.9e-17 63.3 21.3 2.1 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) SDA1 PF05285.12 GAM20776.1 - 0.00026 20.5 16.8 0.00038 20.0 16.8 1.4 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 GAM20776.1 - 0.08 12.3 22.7 0.13 11.6 22.7 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAM20776.1 - 0.23 9.7 14.8 0.33 9.2 14.8 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2076 PF09849.9 GAM20776.1 - 0.36 10.8 12.3 0.6 10.1 12.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PDDEXK_6 PF04720.12 GAM20776.1 - 0.4 10.6 6.5 0.82 9.6 6.5 1.7 1 0 0 1 1 1 0 PDDEXK-like family of unknown function YL1 PF05764.13 GAM20776.1 - 0.77 9.8 28.4 2.8 8.0 28.4 1.8 1 1 0 1 1 1 0 YL1 nuclear protein PPP4R2 PF09184.11 GAM20776.1 - 0.94 9.0 21.8 0.26 10.9 18.2 1.9 2 0 0 2 2 2 0 PPP4R2 LIN37 PF15306.6 GAM20777.1 - 0.00084 19.6 12.6 0.00084 19.6 12.6 3.2 2 1 0 2 2 2 1 LIN37 TFIIA PF03153.13 GAM20777.1 - 0.24 11.4 18.9 0.65 9.9 7.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Palm_thioest PF02089.15 GAM20778.1 - 1.6e-09 38.0 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 GAM20778.1 - 4.9e-08 33.0 0.0 8.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAM20778.1 - 5.5e-07 29.3 0.0 7.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 GAM20778.1 - 1.7e-05 24.3 0.0 3.6e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 GAM20778.1 - 7.4e-05 22.1 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 GAM20778.1 - 0.00037 20.2 0.2 0.0014 18.4 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM20778.1 - 0.00064 20.4 0.0 0.00091 19.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 GAM20778.1 - 0.00072 19.1 0.1 0.0011 18.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S66 PF02016.15 GAM20778.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain Hydrolase_4 PF12146.8 GAM20778.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 GAM20778.1 - 0.025 14.4 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Lipase_2 PF01674.18 GAM20778.1 - 0.03 13.8 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) RNA_pol_3_Rpc31 PF11705.8 GAM20779.1 - 2e-14 54.4 18.5 3.3e-14 53.7 18.5 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 V_ATPase_I PF01496.19 GAM20779.1 - 0.63 7.9 1.7 0.71 7.7 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cwf_Cwc_15 PF04889.12 GAM20779.1 - 3.3 7.4 23.5 0.043 13.6 13.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.14 GAM20779.1 - 3.7 7.3 13.8 0.17 11.6 7.8 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NPR3 PF03666.13 GAM20779.1 - 6.3 5.5 8.6 8.1 5.1 8.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RPN2_C PF18004.1 GAM20779.1 - 6.8 6.6 16.3 0.8 9.6 11.1 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Metallophos PF00149.28 GAM20780.1 - 2.4e-15 57.6 1.0 5.4e-15 56.4 1.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM20780.1 - 6.1e-07 29.8 1.6 1.2e-06 28.8 1.6 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 GAM20780.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Snf7 PF03357.21 GAM20782.1 - 2.6e-32 111.8 29.0 3.4e-32 111.4 29.0 1.1 1 0 0 1 1 1 1 Snf7 DUF1269 PF06897.12 GAM20782.1 - 1.1 9.6 3.5 2.6 8.4 0.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1269) ALMT PF11744.8 GAM20782.1 - 1.2 7.9 14.7 1.4 7.7 14.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DSPc PF00782.20 GAM20782.1 - 8.4 6.2 11.2 12 5.7 5.0 2.3 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain CNOT1_TTP_bind PF16417.5 GAM20783.1 - 1.3e-60 203.8 0.2 4.4e-60 202.1 0.2 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_CAF1_bind PF16415.5 GAM20783.1 - 1.2e-49 168.7 1.2 1.2e-49 168.7 1.2 1.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_HEAT PF16418.5 GAM20783.1 - 6.9e-31 107.3 2.4 2.9e-30 105.3 2.4 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF4327 PF14217.6 GAM20783.1 - 0.08 13.1 0.1 0.42 10.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4327) Aldedh PF00171.22 GAM20784.1 - 1.6e-117 392.9 0.0 1.9e-117 392.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAM20784.1 - 4.9e-06 25.8 0.0 7.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DDE_Tnp_4 PF13359.6 GAM20785.1 - 2.3e-23 82.6 0.4 1.2e-21 77.1 0.3 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM20785.1 - 2.7e-08 33.7 1.9 4.7e-08 32.9 1.9 1.4 1 1 0 1 1 1 1 Transposase DDE domain Metallophos PF00149.28 GAM20786.1 - 8.2e-15 55.9 1.4 1.3e-14 55.2 1.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 GAM20787.1 - 1.2e-15 56.5 18.5 3.5e-06 26.6 2.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TTC5_OB PF16669.5 GAM20787.1 - 2.7e-14 52.8 0.2 5.2e-14 51.9 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_2 PF07719.17 GAM20787.1 - 2.3e-11 42.9 15.3 9.5e-05 22.2 1.4 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM20787.1 - 1.4e-08 34.3 8.9 0.02 15.1 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM20787.1 - 1.8e-08 34.2 6.6 0.052 13.9 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM20787.1 - 2.5e-07 30.9 4.0 0.0012 19.1 0.7 3.7 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM20787.1 - 6.9e-07 28.8 8.9 0.0061 16.2 0.1 4.6 4 1 1 5 5 5 2 TPR repeat TPR_9 PF13371.6 GAM20787.1 - 9.6e-06 25.7 0.1 0.063 13.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM20787.1 - 2e-05 25.2 0.0 0.64 10.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM20787.1 - 0.00036 21.0 1.2 0.5 10.9 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM20787.1 - 0.0013 19.3 0.6 4.2 8.4 0.0 3.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TOM20_plant PF06552.12 GAM20787.1 - 0.012 15.3 0.4 0.033 13.9 0.4 1.9 1 1 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 RNA_pol_Rpb5_C PF01191.19 GAM20787.1 - 0.031 14.1 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain CARDB PF07705.11 GAM20788.1 - 0.0058 16.9 1.7 0.0058 16.9 1.7 2.2 2 0 0 2 2 2 1 CARDB DUF2760 PF10816.8 GAM20788.1 - 0.18 11.6 0.1 0.48 10.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2760) C2 PF00168.30 GAM20789.1 - 1e-17 64.3 0.0 2.2e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 GAM20789.1 - 5.9e-08 33.0 0.4 0.00017 21.8 0.4 3.0 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 GAM20789.1 - 5.3e-05 22.0 0.0 0.00024 19.8 0.0 2.0 1 1 1 2 2 2 1 Plant family of unknown function (DUF810) SPT16 PF08644.11 GAM20789.1 - 0.031 14.5 0.5 0.25 11.5 0.5 2.5 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF4832 PF16116.5 GAM20789.1 - 0.17 11.7 0.6 8.4 6.2 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4832) Transformer PF06495.11 GAM20791.1 - 0.00092 19.4 19.6 0.0012 19.0 19.6 1.3 1 0 0 1 1 1 1 Fruit fly transformer protein SR-25 PF10500.9 GAM20791.1 - 0.0046 16.6 26.8 0.0053 16.4 26.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SEEEED PF14797.6 GAM20791.1 - 0.019 15.1 28.3 0.024 14.8 28.3 1.1 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex DUF4614 PF15391.6 GAM20791.1 - 0.16 11.9 20.1 0.18 11.8 20.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 GAM20791.1 - 1.3 7.5 13.1 1.3 7.5 13.1 1.0 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 GAM20791.1 - 1.5 7.6 16.3 1.4 7.6 16.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PCNP PF15473.6 GAM20791.1 - 1.6 9.5 14.2 1.8 9.3 14.2 1.1 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family NPR3 PF03666.13 GAM20791.1 - 2.4 6.9 12.0 2.6 6.8 12.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 GAM20791.1 - 2.9 6.1 9.2 3.2 5.9 9.2 1.0 1 0 0 1 1 1 0 CDC45-like protein AF-4 PF05110.13 GAM20791.1 - 3.7 5.5 25.9 4.3 5.3 25.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Presenilin PF01080.17 GAM20791.1 - 3.9 6.1 8.6 4.4 6.0 8.6 1.0 1 0 0 1 1 1 0 Presenilin NP1-WLL PF11733.8 GAM20791.1 - 6.9 6.4 16.4 7.8 6.2 16.4 1.0 1 0 0 1 1 1 0 Non-capsid protein NP1 Sel1 PF08238.12 GAM20792.1 - 2.6e-42 142.3 47.7 4.8e-05 23.9 0.1 13.0 12 1 1 13 13 13 8 Sel1 repeat EMC3_TMCO1 PF01956.16 GAM20792.1 - 0.0068 16.1 6.0 0.0068 16.1 6.0 2.6 1 1 1 2 2 2 1 Integral membrane protein EMC3/TMCO1-like Lig_chan PF00060.26 GAM20792.1 - 0.039 13.8 0.8 0.088 12.6 0.8 1.6 1 0 0 1 1 1 0 Ligand-gated ion channel PA26 PF04636.13 GAM20792.1 - 0.13 11.2 10.3 0.26 10.1 10.3 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 GAM20792.1 - 0.18 11.0 3.1 0.33 10.1 3.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Kei1 PF08552.11 GAM20792.1 - 0.48 10.3 4.3 1.3 8.9 4.3 1.7 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 O-antigen_lig PF13425.6 GAM20792.1 - 0.53 9.0 8.8 0.88 8.3 8.8 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Serinc PF03348.15 GAM20792.1 - 0.56 9.1 7.4 1.1 8.1 7.4 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2448 PF10476.9 GAM20792.1 - 0.77 9.6 2.0 1.5 8.6 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) SID-1_RNA_chan PF13965.6 GAM20792.1 - 1.7 7.0 8.6 2.9 6.2 8.6 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 GAM20792.1 - 1.9 7.4 10.0 3.6 6.5 10.0 1.4 1 0 0 1 1 1 0 CLN3 protein SARAF PF06682.12 GAM20792.1 - 2 8.0 14.7 0.058 13.0 7.8 1.8 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Y2_Tnp PF04986.13 GAM20792.1 - 3.2 7.8 7.3 7.6 6.5 7.3 1.6 1 0 0 1 1 1 0 Putative transposase PepSY_TM_like_2 PF16357.5 GAM20792.1 - 3.5 7.6 7.1 8.8 6.2 7.1 1.7 1 0 0 1 1 1 0 Putative PepSY_TM-like EOS1 PF12326.8 GAM20792.1 - 8.7 6.2 7.6 25 4.8 7.6 1.7 1 0 0 1 1 1 0 N-glycosylation protein Nucleo_P87 PF07267.11 GAM20793.1 - 0.22 10.4 12.1 0.24 10.2 12.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SAPS PF04499.15 GAM20793.1 - 1.9 7.2 5.9 1.9 7.2 5.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Dicty_REP PF05086.12 GAM20793.1 - 3.5 5.5 9.0 4 5.3 9.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC27 PF09507.10 GAM20793.1 - 5.3 6.3 36.7 6.1 6.1 36.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 U79_P34 PF03064.16 GAM20793.1 - 7.8 5.8 15.6 12 5.2 15.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TFIID_30kDa PF03540.13 GAM20794.1 - 4.7e-26 90.5 0.0 7.6e-26 89.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 GAM20794.1 - 0.013 15.4 1.1 0.048 13.7 0.1 2.4 2 1 0 2 2 2 0 Bromodomain associated TAF4 PF05236.14 GAM20794.1 - 0.64 9.7 21.7 3.1 7.5 21.7 1.8 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Menin PF05053.13 GAM20794.1 - 0.71 8.2 11.8 0.8 8.0 11.8 1.1 1 0 0 1 1 1 0 Menin SLX9 PF15341.6 GAM20794.1 - 0.99 9.8 17.6 5.6 7.4 17.6 2.0 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 SAPS PF04499.15 GAM20794.1 - 8.9 5.0 10.7 11 4.7 10.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FNIP PF05725.12 GAM20795.1 - 2.1e-51 171.8 10.3 3.1e-11 43.2 0.1 7.8 6 1 0 8 8 8 6 FNIP Repeat FNIP PF05725.12 GAM20796.1 - 4.8e-21 74.6 25.3 5.9e-10 39.1 0.0 8.8 5 2 4 9 9 9 6 FNIP Repeat F-box_5 PF18511.1 GAM20796.1 - 0.0011 18.5 0.1 0.0028 17.2 0.0 1.7 2 0 0 2 2 2 1 F-box ETF_QO PF05187.13 GAM20797.1 - 4.3e-48 161.8 0.2 6.9e-48 161.1 0.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 GAM20797.1 - 4e-08 32.8 0.8 5e-05 22.6 2.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAM20797.1 - 6.4e-08 32.6 0.1 0.00013 21.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 GAM20797.1 - 1e-06 28.2 0.0 8.7e-06 25.1 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 GAM20797.1 - 1.2e-05 25.4 0.0 4.3e-05 23.7 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM20797.1 - 2e-05 25.0 0.1 0.2 12.2 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM20797.1 - 5.1e-05 22.7 0.0 7.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM20797.1 - 5.8e-05 22.0 0.5 0.0001 21.2 0.5 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 GAM20797.1 - 0.00026 21.0 0.1 0.00058 19.9 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAM20797.1 - 0.00074 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM20797.1 - 0.0011 18.1 0.4 0.0016 17.5 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAM20797.1 - 0.0012 18.1 0.3 0.0018 17.6 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 GAM20797.1 - 0.002 18.6 0.4 0.0046 17.5 0.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_binding_3 PF01494.19 GAM20797.1 - 0.003 16.9 0.1 0.0047 16.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.6 GAM20797.1 - 0.0038 16.4 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 GAM20797.1 - 0.067 12.0 0.4 0.22 10.3 0.5 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 GAM20797.1 - 0.21 10.6 0.4 0.31 10.1 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Macoilin PF09726.9 GAM20798.1 - 1.3 7.5 44.1 0.0056 15.3 13.0 2.2 1 1 1 2 2 2 0 Macoilin family MtN3_slv PF03083.16 GAM20799.1 - 3.6e-28 97.4 17.6 3.8e-16 58.9 1.0 3.1 4 0 0 4 4 4 2 Sugar efflux transporter for intercellular exchange HSCB_C PF07743.13 GAM20799.1 - 8.5e-16 58.2 1.8 8.5e-16 58.2 1.8 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 GAM20799.1 - 0.0002 21.4 0.3 0.0002 21.4 0.3 1.8 2 0 0 2 2 2 1 DnaJ domain ORF6N PF10543.9 GAM20799.1 - 0.044 14.0 0.1 0.044 14.0 0.1 1.7 2 0 0 2 2 2 0 ORF6N domain DZR PF12773.7 GAM20799.1 - 0.062 13.3 0.7 0.12 12.4 0.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 GAM20799.1 - 0.11 13.3 0.3 0.11 13.3 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon family DUF413 PF04219.12 GAM20799.1 - 0.19 11.8 0.1 0.52 10.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF DUF1771 PF08590.10 GAM20800.1 - 7.7e-16 58.2 8.9 1.4e-15 57.4 8.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 GAM20800.1 - 5.2e-07 29.2 2.1 5.1e-05 22.9 0.2 2.6 2 0 0 2 2 2 2 CUE domain zf-CCCH_2 PF14608.6 GAM20800.1 - 3.6e-06 27.2 16.4 0.0086 16.5 4.7 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 GAM20800.1 - 5.1e-05 23.4 0.8 0.00012 22.2 0.5 1.8 1 1 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 GAM20800.1 - 0.0017 18.2 11.3 0.0021 17.9 0.9 2.7 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAM20800.1 - 0.034 14.8 0.4 0.034 14.8 0.4 2.8 1 1 1 2 2 2 0 Torus domain DUF1296 PF06972.11 GAM20800.1 - 0.066 13.4 0.6 0.19 11.9 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) zf-CCCH_4 PF18044.1 GAM20800.1 - 0.086 12.7 12.4 0.25 11.2 1.6 3.1 2 1 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAM20800.1 - 0.11 12.6 11.8 0.47 10.6 2.3 4.0 3 1 0 3 3 3 0 Zinc finger domain zf-C3H1 PF10650.9 GAM20800.1 - 0.38 10.5 7.6 4.4 7.1 1.0 2.8 2 0 0 2 2 2 0 Putative zinc-finger domain Pkinase PF00069.25 GAM20801.1 - 4.8e-65 219.5 0.0 7.8e-65 218.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20801.1 - 3.8e-45 154.2 0.0 5.9e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM20801.1 - 0.024 14.6 0.1 0.063 13.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAM20801.1 - 0.042 13.4 0.1 0.042 13.4 0.1 1.6 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 GAM20801.1 - 0.052 12.6 0.2 0.091 11.8 0.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 GAM20801.1 - 0.88 8.3 15.7 17 4.1 15.7 3.1 1 1 0 1 1 1 0 Fungal protein kinase Ctr PF04145.15 GAM20802.1 - 1.7e-18 67.7 16.4 8.9e-16 58.8 16.4 2.1 1 1 0 1 1 1 1 Ctr copper transporter family 7TM_GPCR_Sru PF10322.9 GAM20802.1 - 0.0029 17.0 3.1 0.0037 16.6 3.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sru ERGIC_N PF13850.6 GAM20802.1 - 0.049 14.0 1.5 0.068 13.5 0.3 1.8 1 1 1 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CytochromB561_N PF09786.9 GAM20802.1 - 0.064 12.2 1.0 0.089 11.8 0.7 1.3 1 1 0 1 1 1 0 Cytochrome B561, N terminal Cyclin PF08613.11 GAM20803.1 - 1.1e-31 110.3 0.3 1.1e-31 110.3 0.3 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAM20803.1 - 4.6e-11 42.5 0.0 8.8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Porin_3 PF01459.22 GAM20804.1 - 6e-34 117.7 0.3 9e-34 117.2 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic porin EPL1 PF10513.9 GAM20804.1 - 0.18 12.2 11.3 0.24 11.8 11.3 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Pex14_N PF04695.13 GAM20804.1 - 0.23 12.1 11.7 0.36 11.5 11.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 GAM20804.1 - 0.24 11.0 14.6 0.35 10.4 14.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2828 PF11443.8 GAM20804.1 - 2.3 6.2 12.3 2.9 5.9 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TFIIA PF03153.13 GAM20804.1 - 2.9 7.8 22.2 3.4 7.6 22.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 GAM20804.1 - 3.6 7.1 10.2 4.4 6.8 10.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.9 GAM20804.1 - 7.1 4.8 18.8 8.2 4.5 18.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_15 PF00723.21 GAM20805.1 - 9.9e-17 60.8 0.0 2.3e-16 59.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 15 zf-HIT PF04438.16 GAM20806.1 - 1.3e-06 28.1 7.8 2.3e-06 27.4 7.8 1.4 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 GAM20806.1 - 0.43 8.4 3.7 0.61 7.9 3.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 RNA_capsid PF03035.14 GAM20806.1 - 2.2 8.3 6.4 0.87 9.6 0.2 2.2 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein zf-MYND PF01753.18 GAM20806.1 - 3 8.0 13.8 0.4 10.8 9.4 1.9 2 0 0 2 2 2 0 MYND finger Type_III_YscX PF09474.10 GAM20807.1 - 0.017 15.4 1.3 0.63 10.4 0.5 2.6 1 1 1 2 2 2 0 Type III secretion system YscX (type_III_YscX) EC042_2821 PF18740.1 GAM20808.1 - 0.012 15.5 0.9 0.016 15.1 0.9 1.4 1 1 0 1 1 1 0 EC042_2821-lke REase Uso1_p115_C PF04871.13 GAM20808.1 - 0.072 13.5 6.7 0.093 13.1 6.7 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-H PF05837.12 GAM20808.1 - 2.5 8.5 7.9 48 4.4 7.9 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) zf-NF-X1 PF01422.17 GAM20809.1 - 1.1e-05 25.3 64.2 0.00071 19.6 14.2 16.8 17 0 0 17 17 17 11 NF-X1 type zinc finger Rubella_Capsid PF05750.11 GAM20809.1 - 0.62 9.6 12.8 1.7 8.2 12.8 1.7 1 0 0 1 1 1 0 Rubella capsid protein CLU PF13236.6 GAM20810.1 - 2.6e-55 187.7 0.0 5.9e-55 186.5 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria LRR_4 PF12799.7 GAM20810.1 - 2.4e-10 40.5 40.4 0.14 12.6 0.6 10.0 3 2 7 12 12 12 7 Leucine Rich repeats (2 copies) VHP PF02209.19 GAM20810.1 - 1.2e-09 38.1 1.6 5e-09 36.1 1.6 2.2 1 0 0 1 1 1 1 Villin headpiece domain LRR_6 PF13516.6 GAM20810.1 - 6.1e-07 29.0 30.4 0.11 12.6 0.0 11.5 13 0 0 13 13 13 2 Leucine Rich repeat TPR_11 PF13414.6 GAM20810.1 - 2e-05 24.2 0.3 6e-05 22.6 0.3 1.8 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.6 GAM20810.1 - 5.8e-05 23.2 0.1 0.04 14.3 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat eIF3_p135 PF12807.7 GAM20810.1 - 0.00012 22.2 1.5 0.00051 20.1 1.3 2.2 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TOM20_plant PF06552.12 GAM20810.1 - 0.00047 20.0 0.2 0.015 15.0 0.0 2.7 2 1 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 PPR_long PF17177.4 GAM20810.1 - 0.0033 16.8 0.1 0.0076 15.6 0.1 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP YL1 PF05764.13 GAM20810.1 - 0.024 14.8 16.5 0.056 13.6 16.5 1.6 1 0 0 1 1 1 0 YL1 nuclear protein TPR_19 PF14559.6 GAM20810.1 - 0.044 14.3 0.2 0.45 11.1 0.1 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 GAM20810.1 - 0.16 11.7 22.9 0.41 10.5 1.6 6.9 6 1 2 8 8 8 0 Leucine rich repeat SDA1 PF05285.12 GAM20810.1 - 0.41 10.0 14.1 0.77 9.1 14.1 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GAM20810.1 - 2.2 6.4 16.6 4.4 5.4 16.6 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAM20810.1 - 2.6 6.2 13.9 4.5 5.5 13.9 1.2 1 0 0 1 1 1 0 CDC45-like protein TPR_2 PF07719.17 GAM20810.1 - 4.8 7.5 4.9 45 4.5 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_1 PF00560.33 GAM20810.1 - 6.2 7.8 34.3 1.2e+02 3.8 0.1 12.1 13 1 1 14 14 12 0 Leucine Rich Repeat CIAPIN1 PF05093.13 GAM20811.1 - 4.7e-21 75.2 12.3 1e-19 70.9 12.3 2.3 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Peripla_BP_4 PF13407.6 GAM20811.1 - 0.052 13.1 0.6 0.084 12.4 0.6 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain ELO PF01151.18 GAM20812.1 - 1.4e-62 211.5 23.5 1.6e-62 211.3 23.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3290 PF11694.8 GAM20812.1 - 0.0044 17.0 0.1 0.0044 17.0 0.1 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3290) FNIP PF05725.12 GAM20814.1 - 1.6e-83 274.7 30.4 1.5e-12 47.5 0.1 9.6 7 1 2 10 10 10 8 FNIP Repeat Glyco_hydro_65C PF03633.15 GAM20814.1 - 0.16 11.9 6.4 32 4.5 0.0 6.3 9 0 0 9 9 9 0 Glycosyl hydrolase family 65, C-terminal domain LRR_4 PF12799.7 GAM20815.1 - 0.6 10.6 3.3 5.5 7.6 0.0 3.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) PMM PF03332.13 GAM20816.1 - 1.1e-101 339.2 0.4 1.3e-101 339.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 GAM20816.1 - 0.00033 20.5 0.0 0.0015 18.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 GAM20816.1 - 0.0068 16.0 0.0 0.57 9.7 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 GAM20816.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 GAM20817.1 - 1.6e-56 191.8 23.5 2.2e-38 132.1 3.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM20817.1 - 9.7e-14 51.1 13.2 1.2e-12 47.5 1.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 GAM20817.1 - 3.5e-07 29.1 25.0 2.8e-05 22.9 7.9 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 GAM20817.1 - 2.8e-06 25.9 14.0 0.0031 15.9 0.0 3.5 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 GAM20817.1 - 6.3e-06 25.7 6.1 6.3e-06 25.7 6.1 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 GAM20817.1 - 0.00012 21.1 11.3 0.13 11.1 6.6 3.2 2 1 1 3 3 3 3 MFS_1 like family MFS_3 PF05977.13 GAM20817.1 - 0.0027 16.2 10.5 0.012 14.0 3.7 2.4 2 0 0 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.19 GAM20817.1 - 0.028 13.2 25.0 0.0062 15.4 5.3 2.7 2 1 0 2 2 2 0 LacY proton/sugar symporter BT1 PF03092.16 GAM20817.1 - 0.11 10.8 9.7 0.0073 14.6 0.8 2.9 2 2 1 3 3 3 0 BT1 family Gly-zipper_Omp PF13488.6 GAM20817.1 - 2.9 8.0 8.4 1.4 9.0 3.4 2.8 3 0 0 3 3 3 0 Glycine zipper Ntox27 PF15531.6 GAM20818.1 - 0.15 11.9 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Bacterial toxin 27 DUF2061 PF09834.9 GAM20819.1 - 1.2 9.7 5.8 25 5.5 0.3 3.8 2 1 2 4 4 4 0 Predicted membrane protein (DUF2061) PTPA PF03095.15 GAM20821.1 - 3.6e-111 371.4 0.1 4.3e-111 371.2 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TAP42 PF04177.12 GAM20822.1 - 1.9e-62 211.2 4.4 5.5e-40 137.4 0.8 2.1 1 1 1 2 2 2 2 TAP42-like family FNIP PF05725.12 GAM20823.1 - 8.3e-09 35.5 3.2 0.0041 17.3 0.0 4.4 4 2 0 4 4 4 3 FNIP Repeat zf-RNPHF PF08080.12 GAM20823.1 - 0.095 12.7 0.7 3.3 7.7 0.1 2.5 2 0 0 2 2 2 0 RNPHF zinc finger LapA_dom PF06305.11 GAM20824.1 - 0.18 11.7 0.9 0.35 10.7 0.9 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Vpu PF00558.19 GAM20824.1 - 0.21 11.3 0.2 0.4 10.5 0.2 1.5 1 0 0 1 1 1 0 Vpu protein HC2 PF07382.11 GAM20825.1 - 0.6 10.2 31.2 0.87 9.6 31.2 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Hamartin PF04388.12 GAM20825.1 - 0.81 8.3 37.2 1 7.9 37.2 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 GAM20825.1 - 8.3 4.8 25.5 14 4.1 25.5 1.3 1 0 0 1 1 1 0 Macoilin family DDE_Tnp_4 PF13359.6 GAM20826.1 - 3.8e-27 94.9 0.0 4.8e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM20826.1 - 1.5e-10 41.0 0.0 2.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Peptidase_C1 PF00112.23 GAM20827.1 - 3.5e-75 252.8 9.1 4.7e-75 252.4 9.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM20827.1 - 1.6e-14 54.0 5.4 3.2e-14 53.1 5.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAM20827.1 - 6.1e-05 22.0 1.0 0.01 14.6 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family RasGEF PF00617.19 GAM20828.1 - 1.4e-55 188.2 0.4 1.4e-55 188.2 0.4 2.9 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM20828.1 - 2.4e-24 85.6 0.8 2.4e-24 85.6 0.8 3.1 3 0 0 3 3 3 1 RasGEF N-terminal motif SHMT PF00464.19 GAM20829.1 - 4.1e-190 631.6 0.0 4.7e-190 631.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 GAM20829.1 - 0.016 14.5 0.0 0.067 12.5 0.0 1.9 1 1 0 1 1 1 0 Beta-eliminating lyase FNIP PF05725.12 GAM20830.1 - 5.8e-43 144.8 17.2 4.7e-10 39.5 0.0 7.9 5 1 3 9 9 9 8 FNIP Repeat EGF_2 PF07974.13 GAM20831.1 - 0.0015 18.8 13.5 0.0028 18.0 13.5 1.5 1 0 0 1 1 1 1 EGF-like domain CYYR1 PF10873.8 GAM20831.1 - 0.11 13.0 2.9 0.094 13.2 0.6 2.1 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 FNIP PF05725.12 GAM20833.1 - 2.5e-56 187.6 31.8 5e-12 45.8 0.3 9.6 5 3 4 10 10 10 9 FNIP Repeat LRR_8 PF13855.6 GAM20833.1 - 0.45 10.3 14.0 6.9 6.5 1.5 5.3 3 1 1 5 5 5 0 Leucine rich repeat ABC2_membrane_3 PF12698.7 GAM20834.1 - 2.6e-30 105.7 30.9 3.6e-30 105.3 30.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 GAM20834.1 - 2.1e-24 86.6 0.0 3.8e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM20834.1 - 6.4e-10 39.3 0.2 6.2e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 GAM20834.1 - 1.3e-05 24.7 19.7 1.3e-05 24.7 19.7 3.2 3 0 0 3 3 3 2 ABC-2 type transporter AAA_23 PF13476.6 GAM20834.1 - 0.0064 17.0 0.3 0.012 16.1 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 GAM20834.1 - 0.011 15.5 0.0 2.9 7.5 0.1 2.3 1 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 GAM20834.1 - 0.092 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1899 PF08953.11 GAM20835.1 - 1.9e-32 110.9 2.2 2e-32 110.9 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 GAM20835.1 - 4.8e-20 71.2 0.1 7.9e-20 70.5 0.1 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 GAM20835.1 - 1.1e-14 54.6 3.1 0.0011 19.8 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM20835.1 - 5.9e-05 23.3 0.6 0.063 13.6 0.1 3.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM20835.1 - 0.038 12.9 0.0 0.54 9.2 0.0 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DNase_II PF03265.15 GAM20835.1 - 0.05 12.9 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Deoxyribonuclease II CLU PF13236.6 GAM20836.1 - 1.1e-60 205.2 0.0 2.3e-60 204.2 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria LRR_4 PF12799.7 GAM20836.1 - 2.6e-10 40.4 22.1 0.095 13.2 0.0 8.7 4 1 4 9 9 9 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAM20836.1 - 4.1e-07 29.5 26.2 0.3 11.2 0.1 10.6 12 0 0 12 12 12 4 Leucine Rich repeat eIF3_p135 PF12807.7 GAM20836.1 - 5e-07 29.9 0.0 5e-07 29.9 0.0 2.5 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 LRR_8 PF13855.6 GAM20836.1 - 1.4 8.8 8.2 8.1 6.3 0.0 5.2 7 0 0 7 7 7 0 Leucine rich repeat ATP-synt_G PF04718.15 GAM20838.1 - 2.3e-06 28.4 0.2 2.9e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Ras PF00071.22 GAM20839.1 - 1.3e-57 193.9 0.0 1.6e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM20839.1 - 4.2e-24 85.1 0.0 6.3e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM20839.1 - 6e-09 35.6 0.0 7.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM20839.1 - 0.00046 19.8 0.0 0.0014 18.2 0.0 1.6 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Pro-kuma_activ PF09286.11 GAM20840.1 - 6.4e-29 101.1 0.2 7.4e-29 100.9 0.2 1.1 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain P5-ATPase PF12409.8 GAM20842.1 - 0.024 14.7 2.6 0.031 14.4 2.6 1.2 1 0 0 1 1 1 0 P5-type ATPase cation transporter ArfGap PF01412.18 GAM20843.1 - 3.9e-40 136.6 0.5 1.4e-39 134.8 0.5 2.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 GAM20843.1 - 1.8e-20 73.7 7.0 3.5e-20 72.8 7.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 GAM20843.1 - 4.4e-16 59.3 0.1 1.3e-15 57.8 0.1 1.9 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 GAM20843.1 - 5.8e-10 39.5 0.1 1e-08 35.5 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) BAR PF03114.18 GAM20843.1 - 4.4e-09 36.3 6.3 7.4e-09 35.6 6.3 1.4 1 0 0 1 1 1 1 BAR domain Ank_2 PF12796.7 GAM20843.1 - 6.8e-09 36.2 0.0 1.9e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM20843.1 - 7.2e-09 35.7 0.0 2.6e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM20843.1 - 4.9e-06 26.8 0.0 0.0092 16.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat PH_11 PF15413.6 GAM20843.1 - 0.00021 21.7 0.0 0.0011 19.4 0.0 2.4 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_3 PF13606.6 GAM20843.1 - 0.0012 19.2 0.0 0.033 14.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat BAR_2 PF10455.9 GAM20843.1 - 0.0031 16.7 3.4 0.008 15.4 3.4 1.7 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PH_9 PF15410.6 GAM20843.1 - 0.0048 17.3 0.1 0.0048 17.3 0.1 2.5 3 0 0 3 3 3 1 Pleckstrin homology domain PH_4 PF15404.6 GAM20843.1 - 0.02 14.7 0.1 0.46 10.3 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain PH_13 PF16652.5 GAM20843.1 - 0.049 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain RNase_H PF00075.24 GAM20844.1 - 2.4e-37 128.3 0.0 3e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 GAM20844.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like RNase_H PF00075.24 GAM20845.1 - 1.7e-43 148.2 0.4 2.1e-43 147.9 0.4 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 GAM20845.1 - 0.00024 20.9 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Clathrin_bdg PF15045.6 GAM20845.1 - 0.046 13.7 0.2 0.081 12.9 0.2 1.3 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking ELMO_CED12 PF04727.13 GAM20846.1 - 1.8e-37 129.1 0.5 8.3e-37 127.0 0.4 2.2 2 0 0 2 2 2 1 ELMO/CED-12 family RasGEF_N PF00618.20 GAM20846.1 - 0.4 11.0 2.2 8 6.8 0.1 3.6 3 0 0 3 3 3 0 RasGEF N-terminal motif 7tm_1 PF00001.21 GAM20848.1 - 3.2e-14 52.9 11.8 4.1e-14 52.5 11.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 GAM20848.1 - 6.8e-12 45.2 11.0 8.3e-12 44.9 11.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 GAM20848.1 - 1.4e-10 40.9 13.1 1.9e-09 37.1 8.9 2.0 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Frizzled PF01534.17 GAM20848.1 - 0.0013 17.9 11.7 0.0019 17.3 11.7 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region GPR_Gpa2_C PF11970.8 GAM20848.1 - 0.0038 17.2 4.2 0.0044 17.0 0.2 2.8 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Ocular_alb PF02101.15 GAM20848.1 - 0.066 12.1 18.9 0.52 9.2 14.2 2.9 2 2 0 2 2 2 0 Ocular albinism type 1 protein Med9 PF07544.13 GAM20849.1 - 0.045 13.8 1.0 0.076 13.1 1.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.15 GAM20849.1 - 0.081 12.7 0.6 0.1 12.3 0.6 1.2 1 0 0 1 1 1 0 Septum formation initiator CHAT PF12770.7 GAM20849.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 CHAT domain FAM76 PF16046.5 GAM20849.1 - 0.13 11.5 0.2 0.15 11.4 0.2 1.0 1 0 0 1 1 1 0 FAM76 protein RPW8 PF05659.11 GAM20849.1 - 0.14 11.9 0.3 0.17 11.6 0.3 1.1 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RabGAP-TBC PF00566.18 GAM20850.1 - 7e-57 192.5 3.2 7e-57 192.5 3.2 2.7 4 0 0 4 4 4 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 GAM20850.1 - 1.7e-53 179.1 6.4 1.5e-12 47.9 0.0 5.6 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20850.1 - 1.1e-50 169.4 12.6 1.1e-11 45.0 0.1 8.4 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 GAM20850.1 - 2.1e-47 157.6 8.2 9.3e-06 25.9 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 GAM20850.1 - 9.3e-40 134.2 8.9 1.3e-07 31.7 0.0 6.7 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20850.1 - 1.1e-37 123.8 5.4 0.00065 20.0 0.1 9.5 9 0 0 9 9 9 8 Ankyrin repeat DUF4988 PF16378.5 GAM20850.1 - 0.08 12.6 0.1 2.8 7.6 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function Patatin PF01734.22 GAM20851.1 - 1.7e-16 61.0 1.4 3.7e-15 56.7 1.4 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4347 PF14252.6 GAM20851.1 - 0.016 15.1 0.6 0.04 13.8 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) Trimer_CC PF08954.11 GAM20851.1 - 0.27 10.8 2.6 1.8 8.2 2.4 2.2 2 0 0 2 2 2 0 Trimerisation motif Rad10 PF03834.14 GAM20851.1 - 0.51 10.4 4.0 0.99 9.4 0.3 2.5 2 1 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Yippee-Mis18 PF03226.14 GAM20852.1 - 4.2e-18 65.5 0.5 4.9e-18 65.3 0.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 GAM20852.1 - 0.00028 21.1 0.9 0.00038 20.7 0.9 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF1951 PF09188.10 GAM20852.1 - 0.019 15.0 0.1 0.023 14.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) DUF4077 PF13295.6 GAM20853.1 - 0.0064 16.4 4.1 0.01 15.8 4.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4077) YceD PF02620.17 GAM20853.1 - 0.18 11.9 2.9 11 6.2 2.8 2.5 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD SR-25 PF10500.9 GAM20853.1 - 0.73 9.4 5.2 1.7 8.2 5.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EF-hand_7 PF13499.6 GAM20854.1 - 5.8e-09 36.3 2.4 1.2e-05 25.6 1.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM20854.1 - 3e-06 26.7 13.0 0.0099 15.8 0.2 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 GAM20854.1 - 1.1e-05 24.6 8.8 0.0045 16.4 0.2 3.7 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 GAM20854.1 - 3.4e-05 24.1 0.3 0.16 12.3 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAM20854.1 - 0.0003 20.6 3.6 0.0064 16.3 0.4 3.4 3 0 0 3 3 3 1 EF-hand domain pair UBA PF00627.31 GAM20854.1 - 0.0057 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain PhnA_Zn_Ribbon PF08274.12 GAM20854.1 - 0.44 10.5 2.6 1.1 9.2 2.6 1.7 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Presenilin PF01080.17 GAM20854.1 - 2 7.1 6.4 3.4 6.3 6.4 1.3 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 GAM20854.1 - 2.1 8.5 6.5 6.9 6.8 6.5 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Sec62 PF03839.16 GAM20854.1 - 2.2 7.7 4.9 5.4 6.5 4.9 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 DNA_RNApol_7kD PF03604.13 GAM20854.1 - 9.8 6.0 7.6 8.2 6.2 1.0 2.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit MMR_HSR1 PF01926.23 GAM20855.1 - 4.7e-06 26.7 0.2 8.7e-06 25.8 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 GAM20855.1 - 0.00019 20.8 0.1 0.00036 19.9 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Roc PF08477.13 GAM20855.1 - 0.014 15.6 0.9 0.12 12.5 0.5 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BID PF06393.11 GAM20855.1 - 0.017 14.7 0.5 0.027 14.0 0.5 1.3 1 0 0 1 1 1 0 BH3 interacting domain (BID) Polo_box_2 PF18531.1 GAM20855.1 - 0.037 14.1 0.8 0.12 12.5 0.8 1.8 1 0 0 1 1 1 0 Polo box domain STAG PF08514.11 GAM20855.1 - 0.048 13.6 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 STAG domain Kelch_6 PF13964.6 GAM20856.1 - 1.2e-06 28.5 5.6 0.00057 20.1 0.1 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 GAM20856.1 - 6.4e-05 22.8 0.1 1.3 9.1 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM20856.1 - 0.00021 21.2 12.2 0.0028 17.6 0.0 5.0 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM20856.1 - 0.12 12.0 0.1 0.12 12.0 0.1 4.7 5 0 0 5 5 5 0 Kelch motif PQQ_3 PF13570.6 GAM20856.1 - 0.16 12.5 3.9 4 8.1 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Kelch_5 PF13854.6 GAM20856.1 - 1 9.5 3.9 5.9 7.0 0.1 2.9 3 0 0 3 3 3 0 Kelch motif Big_7 PF17957.1 GAM20857.1 - 0.00059 20.6 0.8 0.0011 19.7 0.8 1.5 1 0 0 1 1 1 1 Bacterial Ig domain Peptidase_C48 PF02902.19 GAM20860.1 - 1e-35 123.5 1.7 4.5e-35 121.5 1.7 2.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FAM91_C PF14648.6 GAM20861.1 - 2e-145 485.0 0.0 3.6e-117 391.8 0.0 2.1 1 1 1 2 2 2 2 FAM91 C-terminus FAM91_N PF14647.6 GAM20861.1 - 2.6e-118 394.8 0.5 3.7e-118 394.3 0.5 1.2 1 0 0 1 1 1 1 FAM91 N-terminus Pkinase_Tyr PF07714.17 GAM20862.1 - 4.1e-46 157.4 0.0 6.1e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM20862.1 - 1.1e-44 152.8 0.0 2.1e-44 151.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 GAM20862.1 - 6.4e-24 84.2 0.0 1.8e-23 82.8 0.0 1.8 2 0 0 2 2 1 1 C2 domain Ank_4 PF13637.6 GAM20862.1 - 6.5e-19 68.0 1.5 1.6e-05 25.4 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM20862.1 - 6.8e-19 68.2 2.4 1.4e-11 44.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM20862.1 - 3.3e-15 54.7 0.9 0.00066 19.9 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAM20862.1 - 8.2e-15 54.7 0.3 0.0001 22.5 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM20862.1 - 1.4e-14 53.8 0.2 0.002 18.5 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat SAM_2 PF07647.17 GAM20862.1 - 3.6e-06 27.0 0.0 9.8e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAM20862.1 - 1.6e-05 25.3 0.1 8.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) APH PF01636.23 GAM20862.1 - 0.034 14.1 0.1 0.082 12.8 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM20862.1 - 0.049 12.6 4.1 0.11 11.5 2.3 2.4 2 1 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM20862.1 - 0.073 11.8 0.0 0.16 10.7 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase RAP1 PF07218.11 GAM20862.1 - 0.71 8.1 9.2 1 7.5 9.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 GAM20862.1 - 8.1 4.9 6.9 14 4.1 6.9 1.3 1 0 0 1 1 1 0 Macoilin family Ribosomal_S14 PF00253.21 GAM20863.1 - 2.4e-14 52.8 2.7 2.7e-14 52.7 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF1451 PF07295.11 GAM20863.1 - 0.038 14.0 0.7 0.05 13.6 0.7 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain Pkinase PF00069.25 GAM20864.1 - 1.7e-66 224.3 0.0 2.1e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20864.1 - 6.7e-26 91.1 0.1 1.7e-25 89.8 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM20864.1 - 9.5e-07 28.4 0.1 1.8e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAM20864.1 - 0.0029 17.6 0.0 0.049 13.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM20864.1 - 0.0085 15.7 0.2 0.016 14.8 0.2 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 GAM20864.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chor_lyase PF04345.13 GAM20864.1 - 0.064 12.9 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Chorismate lyase FTA2 PF13095.6 GAM20864.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Defensin_2 PF01097.18 GAM20865.1 - 6.7 6.7 11.7 0.3 11.1 1.0 3.0 3 0 0 3 3 3 0 Arthropod defensin PhoLip_ATPase_C PF16212.5 GAM20866.1 - 3.3e-49 167.9 20.4 3.3e-49 167.9 20.4 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 GAM20866.1 - 9.3e-12 45.7 0.4 6.7e-05 23.3 0.2 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM20866.1 - 3.3e-11 43.1 0.1 1.9e-09 37.5 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GAM20866.1 - 2.5e-10 40.2 2.3 5.5e-10 39.1 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAM20866.1 - 0.00058 19.7 1.4 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 GAM20866.1 - 0.0021 17.7 0.5 0.0078 15.9 0.5 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal RRM_1 PF00076.22 GAM20867.1 - 2.3e-14 52.9 0.0 4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM20867.1 - 0.0089 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM20867.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 GAM20867.1 - 0.066 13.3 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif RL PF17797.1 GAM20867.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 RL domain Peptidase_M16_M PF16187.5 GAM20868.1 - 1.4e-39 136.1 1.5 1.4e-39 136.1 1.5 1.5 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAM20868.1 - 1e-31 109.9 0.1 2.7e-31 108.6 0.1 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAM20868.1 - 2.5e-21 76.5 0.0 1.2e-12 48.3 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain UCH PF00443.29 GAM20869.1 - 2e-22 79.9 8.5 1e-21 77.6 8.5 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CBM_20 PF00686.19 GAM20869.1 - 2.3e-16 59.5 2.6 1.6e-07 31.1 0.1 3.5 3 0 0 3 3 3 3 Starch binding domain His_binding PF02098.16 GAM20869.1 - 0.043 13.9 0.8 0.12 12.4 0.8 1.7 1 0 0 1 1 1 0 Tick histamine binding protein MucB_RseB_C PF17188.4 GAM20869.1 - 0.051 13.8 0.3 0.12 12.7 0.3 1.5 1 0 0 1 1 1 0 MucB/RseB C-terminal domain UPF0515 PF15135.6 GAM20869.1 - 0.068 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 HAP2-GCS1 PF10699.9 GAM20870.1 - 0.0015 18.4 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 Male gamete fusion factor Ank_2 PF12796.7 GAM20871.1 - 5.6e-06 26.9 13.0 0.54 10.9 0.1 7.8 7 4 3 10 10 10 4 Ankyrin repeats (3 copies) DUF3447 PF11929.8 GAM20871.1 - 0.02 14.9 11.4 0.89 9.6 0.1 5.8 5 1 0 5 5 5 0 Domain of unknown function (DUF3447) Ank_3 PF13606.6 GAM20871.1 - 3.4 8.5 9.4 2.3e+02 2.9 0.1 8.1 12 0 0 12 12 12 0 Ankyrin repeat Bromo_TP PF07524.13 GAM20872.1 - 5.7e-16 58.3 0.1 9.8e-16 57.5 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 GAM20872.1 - 9.8e-16 58.0 1.3 9.8e-16 58.0 1.3 2.3 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP_like PF17027.5 GAM20872.1 - 0.0087 16.2 0.1 0.02 15.1 0.1 1.5 1 0 0 1 1 1 1 Histone-fold protein Tim17 PF02466.19 GAM20873.1 - 0.048 14.0 1.0 0.079 13.3 1.0 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Trm112p PF03966.16 GAM20874.1 - 1.4e-10 41.6 0.1 2.1e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein zinc_ribbon_4 PF13717.6 GAM20874.1 - 0.045 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon domain IZUMO PF15005.6 GAM20874.1 - 0.058 13.9 0.4 0.058 13.9 0.4 1.8 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated GST_C PF00043.25 GAM20875.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM20875.1 - 6e-12 45.7 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM20875.1 - 8.4e-12 45.1 0.3 3.3e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM20875.1 - 7.3e-10 38.7 0.2 2.2e-09 37.2 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM20875.1 - 1.6e-08 34.8 0.0 4.5e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM20875.1 - 1.7e-08 34.6 0.0 3.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAM20875.1 - 0.0081 15.9 0.0 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Peptidase_M66 PF10462.9 GAM20876.1 - 2.2e-58 197.6 0.0 2.9e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase M66 Gly-zipper_YMGG PF13441.6 GAM20877.1 - 1.3 8.8 76.4 1.3e+03 -0.8 30.4 3.8 1 1 2 3 3 3 0 YMGG-like Gly-zipper ELFV_dehydrog PF00208.21 GAM20879.1 - 1.2e-50 172.6 0.0 1.9e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 GAM20879.1 - 2.8e-23 81.5 0.1 5.3e-15 54.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 GAM20879.1 - 0.16 11.8 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pro-kuma_activ PF09286.11 GAM20880.1 - 9e-33 113.6 1.1 1.5e-32 112.9 0.6 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM20880.1 - 2.5e-06 27.0 3.4 5.1e-06 26.0 3.4 1.5 1 0 0 1 1 1 1 Subtilase family RRM_1 PF00076.22 GAM20881.1 - 1.7e-14 53.3 0.0 2.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 GAM20881.1 - 1e-06 28.5 14.8 5.4e-06 26.2 3.3 2.9 3 0 0 3 3 3 2 Zinc knuckle DUF2318 PF10080.9 GAM20881.1 - 0.021 14.9 0.4 0.032 14.3 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DnaJ_CXXCXGXG PF00684.19 GAM20881.1 - 0.039 14.3 5.4 0.096 13.1 5.4 1.7 1 0 0 1 1 1 0 DnaJ central domain RRM_5 PF13893.6 GAM20881.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.6 GAM20881.1 - 5 6.9 6.9 2.9 7.7 1.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 GAM20881.1 - 8.6 6.4 8.9 18 5.4 1.9 2.5 1 1 1 2 2 2 0 Zinc knuckle PG_binding_1 PF01471.18 GAM20882.1 - 1.2e-06 28.6 0.0 1.1e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Rhodanese PF00581.20 GAM20882.1 - 0.14 12.7 0.5 0.52 10.8 0.1 2.2 2 0 0 2 2 2 0 Rhodanese-like domain FlaC_arch PF05377.11 GAM20882.1 - 1.6 9.2 9.3 0.69 10.4 0.8 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1241 PF06840.11 GAM20882.1 - 2 8.1 6.4 4.5 6.9 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1241) CorA PF01544.18 GAM20882.1 - 3.5 6.9 17.8 0.046 13.0 8.2 2.6 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein FAM76 PF16046.5 GAM20882.1 - 4.7 6.5 18.4 6.6 6.0 5.4 2.8 2 0 0 2 2 2 0 FAM76 protein PHR PF08005.12 GAM20883.1 - 1.8e-31 109.8 4.7 7e-31 107.9 2.7 2.9 2 0 0 2 2 2 1 PHR domain zf-RING_2 PF13639.6 GAM20883.1 - 1.1e-06 28.8 8.6 1.1e-06 28.8 8.6 5.2 5 0 0 5 5 5 1 Ring finger domain ANAPC10 PF03256.16 GAM20883.1 - 1.3e-05 24.9 0.0 3.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) zf-RING_5 PF14634.6 GAM20883.1 - 0.001 19.0 6.0 0.001 19.0 6.0 4.9 4 0 0 4 4 4 1 zinc-RING finger domain zf-B_box PF00643.24 GAM20883.1 - 0.0033 17.6 5.4 0.0033 17.6 5.4 4.1 3 1 0 3 3 3 1 B-box zinc finger FNIP PF05725.12 GAM20884.1 - 2.6e-72 238.7 0.1 4.6e-14 52.3 0.0 9.0 6 2 3 10 10 10 9 FNIP Repeat Ald_deCOase PF11266.8 GAM20884.1 - 0.17 11.6 0.0 11 5.6 0.0 3.0 3 0 0 3 3 3 0 Long-chain fatty aldehyde decarbonylase Menin PF05053.13 GAM20884.1 - 0.8 8.0 4.1 1.1 7.5 4.1 1.1 1 0 0 1 1 1 0 Menin NAM-associated PF14303.6 GAM20884.1 - 1.9 9.1 7.0 3 8.5 7.0 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF515 PF04415.12 GAM20884.1 - 5.1 5.4 10.9 7.9 4.7 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PH PF00169.29 GAM20885.1 - 4.3e-14 52.9 0.1 1.4e-13 51.2 0.1 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM20885.1 - 6.8e-10 39.3 0.4 2.8e-09 37.3 0.4 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAM20885.1 - 6.2e-05 23.2 0.8 0.00024 21.3 0.8 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 GAM20885.1 - 0.085 13.2 0.3 0.35 11.2 0.3 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain adh_short PF00106.25 GAM20886.1 - 2.9e-25 88.9 2.5 2.2e-21 76.2 0.1 2.5 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM20886.1 - 1e-17 64.5 0.2 6.5e-16 58.6 0.2 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM20886.1 - 9.1e-06 25.7 0.2 1.4e-05 25.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM20886.1 - 0.00016 21.2 0.1 0.00021 20.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAM20886.1 - 0.0013 18.2 0.1 0.005 16.3 0.1 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 GAM20886.1 - 0.02 14.3 0.6 0.025 14.0 0.6 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pyr_redox_3 PF13738.6 GAM20886.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Spc29 PF17082.5 GAM20887.1 - 0.014 15.3 0.5 0.014 15.3 0.5 2.2 2 0 0 2 2 2 0 Spindle Pole Component 29 KASH_CCD PF14662.6 GAM20887.1 - 0.03 14.2 5.2 0.059 13.2 5.2 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH PRKG1_interact PF15898.5 GAM20887.1 - 0.19 12.7 8.7 1.7 9.6 0.0 3.1 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain FPP PF05911.11 GAM20887.1 - 0.95 7.6 10.2 0.058 11.6 4.9 1.5 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF5101 PF17031.5 GAM20887.1 - 3.6 7.7 9.7 0.33 11.1 4.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) Actin PF00022.19 GAM20888.1 - 6.3e-110 367.6 0.0 4.9e-57 193.4 0.0 2.0 1 1 1 2 2 2 2 Actin Gelsolin PF00626.22 GAM20889.1 - 2.8e-42 142.5 0.0 1.3e-12 47.4 0.0 5.5 5 0 0 5 5 5 5 Gelsolin repeat VHP PF02209.19 GAM20889.1 - 9.1e-13 48.0 0.1 2.1e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 Villin headpiece domain PH PF00169.29 GAM20889.1 - 1.3e-12 48.2 0.1 2.5e-07 31.2 0.0 3.2 3 0 0 3 3 3 2 PH domain WD40 PF00400.32 GAM20889.1 - 1.4e-10 41.5 3.2 8.9e-06 26.4 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40_4 PF16300.5 GAM20889.1 - 9.9e-09 35.0 0.1 2.2e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 GAM20889.1 - 3.1e-08 33.4 0.0 8.4e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) NMT PF01233.19 GAM20892.1 - 1.1e-76 256.1 0.1 1.7e-76 255.5 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 GAM20892.1 - 1.5e-66 223.9 0.0 2.3e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 GAM20892.1 - 0.00026 21.1 0.0 0.096 12.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM20892.1 - 0.045 14.0 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PspC PF04024.12 GAM20892.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 PspC domain LRR_4 PF12799.7 GAM20893.1 - 0.00073 19.9 0.4 0.024 15.1 0.1 2.7 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) DUF3234 PF11572.8 GAM20893.1 - 0.13 12.4 0.0 0.64 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3234) LRR_6 PF13516.6 GAM20893.1 - 0.39 10.9 4.3 1.9 8.7 0.4 3.0 3 0 0 3 3 3 0 Leucine Rich repeat PTSIIA_gutA PF03829.13 GAM20894.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 PTS system glucitol/sorbitol-specific IIA component Copine PF07002.16 GAM20894.1 - 0.17 11.3 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Copine DDOST_48kD PF03345.14 GAM20895.1 - 1.8e-65 221.4 0.3 2.1e-65 221.2 0.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4419 PF14388.6 GAM20896.1 - 1.2e-98 330.3 0.2 1.4e-98 330.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) MreD PF04093.12 GAM20896.1 - 0.12 12.4 0.0 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 rod shape-determining protein MreD Kelch_6 PF13964.6 GAM20897.1 - 4.6e-13 49.0 0.9 0.00051 20.2 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM20897.1 - 8.1e-10 38.6 3.0 0.013 15.5 0.0 5.0 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM20897.1 - 1e-06 28.2 0.1 0.0015 18.1 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 GAM20897.1 - 0.00054 20.2 0.1 55 4.2 0.0 4.9 5 0 0 5 5 5 0 Galactose oxidase, central domain Fibin PF15819.5 GAM20897.1 - 0.073 12.8 0.6 0.16 11.7 0.3 1.6 2 0 0 2 2 2 0 Fin bud initiation factor homologue MAP65_ASE1 PF03999.12 GAM20897.1 - 0.53 8.9 2.2 0.74 8.4 2.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pkinase_Tyr PF07714.17 GAM20898.1 - 2.9e-48 164.4 0.0 5e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM20898.1 - 2e-43 148.7 0.0 1e-40 139.8 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain COR PF16095.5 GAM20898.1 - 3.6e-41 141.1 0.3 1.4e-40 139.2 0.0 2.2 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain RasGEF PF00617.19 GAM20898.1 - 5e-36 124.6 0.1 1.6e-35 122.9 0.1 1.9 1 0 0 1 1 1 1 RasGEF domain Roc PF08477.13 GAM20898.1 - 2.9e-21 75.9 0.1 8.1e-21 74.5 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase cNMP_binding PF00027.29 GAM20898.1 - 1.6e-20 72.9 0.0 3e-09 36.8 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DEP PF00610.21 GAM20898.1 - 2.2e-13 50.0 0.3 6.5e-12 45.3 0.0 3.0 3 0 0 3 3 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ras PF00071.22 GAM20898.1 - 7.5e-12 45.1 0.6 1.6e-11 44.1 0.6 1.5 1 0 0 1 1 1 1 Ras family LRR_8 PF13855.6 GAM20898.1 - 7.9e-10 38.4 15.2 0.00013 21.6 4.3 3.1 2 0 0 2 2 2 2 Leucine rich repeat RasGEF_N PF00618.20 GAM20898.1 - 5.9e-09 36.1 3.1 1.8e-08 34.6 0.2 3.1 3 0 0 3 3 3 1 RasGEF N-terminal motif GRAM PF02893.20 GAM20898.1 - 1e-08 35.0 0.6 2.8e-08 33.6 0.6 1.8 1 0 0 1 1 1 1 GRAM domain LRR_4 PF12799.7 GAM20898.1 - 2.5e-08 34.1 17.1 7e-05 23.1 3.8 4.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) APH PF01636.23 GAM20898.1 - 0.0046 16.9 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC_tran PF00005.27 GAM20898.1 - 0.0097 16.4 0.0 0.0097 16.4 0.0 2.6 3 0 0 3 3 2 1 ABC transporter LRR_9 PF14580.6 GAM20898.1 - 0.028 13.9 4.5 0.072 12.6 4.5 1.7 1 0 0 1 1 1 0 Leucine-rich repeat MMR_HSR1 PF01926.23 GAM20898.1 - 0.08 13.0 0.3 0.28 11.3 0.0 2.1 2 0 0 2 2 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAM20898.1 - 0.33 11.0 4.2 0.43 10.6 0.2 2.8 2 0 0 2 2 2 0 Dynamin family AIG1 PF04548.16 GAM20898.1 - 0.68 9.2 4.2 0.16 11.2 0.1 2.0 2 0 0 2 2 2 0 AIG1 family LRR_1 PF00560.33 GAM20898.1 - 2.3 9.1 9.4 30 5.7 0.2 5.3 5 0 0 5 5 4 0 Leucine Rich Repeat CtnDOT_TraJ PF07863.11 GAM20900.1 - 0.066 13.9 0.2 0.12 13.1 0.2 1.4 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon Ank_2 PF12796.7 GAM20901.1 - 5.9e-41 139.0 23.3 3.7e-09 37.1 0.6 6.8 2 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20901.1 - 3e-32 110.6 12.8 1.9e-05 25.1 0.1 8.6 6 1 4 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20901.1 - 1.1e-31 108.5 14.3 0.0087 16.4 0.1 13.0 3 2 11 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20901.1 - 5.7e-22 75.4 5.4 2.3 9.1 0.0 13.4 15 0 0 15 15 15 5 Ankyrin repeat DUF5049 PF16468.5 GAM20901.1 - 8.1e-08 32.0 0.9 9.1 6.3 0.0 7.7 5 2 3 8 8 8 2 Domain of unknown function (DUF5049) Ank PF00023.30 GAM20901.1 - 3.8e-06 27.1 7.1 16 6.2 0.1 9.4 6 2 2 9 9 9 1 Ankyrin repeat HTH_22 PF13309.6 GAM20901.1 - 0.0066 16.5 0.0 7.9 6.6 0.0 3.4 2 0 0 2 2 2 2 HTH domain DUF4031 PF13223.6 GAM20901.1 - 0.27 11.5 2.4 23 5.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4031) Ank_2 PF12796.7 GAM20902.1 - 1.1e-89 295.2 49.1 1.5e-11 44.7 0.7 15.6 7 4 8 17 17 17 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20902.1 - 6e-87 285.0 60.5 3.3e-07 30.7 0.0 22.1 14 5 10 24 24 24 20 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20902.1 - 1.5e-70 232.3 71.6 0.0002 21.6 0.0 32.8 7 4 29 36 36 36 22 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20902.1 - 4.4e-38 124.9 35.0 0.04 14.5 0.0 28.7 32 3 3 35 35 29 3 Ankyrin repeat DUF5049 PF16468.5 GAM20902.1 - 4.3e-13 48.9 24.4 22 5.0 0.0 17.6 15 7 8 23 23 22 0 Domain of unknown function (DUF5049) Ank PF00023.30 GAM20902.1 - 2.1e-12 46.9 29.4 2.2 8.9 0.0 20.3 9 5 6 15 15 15 1 Ankyrin repeat DUF2790 PF10976.8 GAM20902.1 - 4.6e-07 29.7 1.3 2.7 8.1 0.0 7.4 7 1 1 8 8 8 1 Protein of unknown function (DUF2790) HTH_22 PF13309.6 GAM20902.1 - 0.00019 21.4 0.0 2.3 8.4 0.0 5.3 4 0 0 4 4 3 1 HTH domain Ependymin PF00811.18 GAM20902.1 - 0.0012 19.1 0.1 41 4.4 0.0 6.3 6 1 1 7 7 7 0 Ependymin AhpC-TSA PF00578.21 GAM20902.1 - 0.061 13.2 0.0 27 4.7 0.0 4.7 5 1 1 6 6 6 0 AhpC/TSA family SAD_SRA PF02182.17 GAM20902.1 - 0.066 12.9 0.0 5.7 6.6 0.0 3.0 2 0 0 2 2 2 0 SAD/SRA domain DUF4751 PF15942.5 GAM20902.1 - 0.084 12.8 4.7 3.6 7.5 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4751) VWA_3_C PF18571.1 GAM20902.1 - 0.1 12.5 0.6 3.1e+02 1.3 0.0 5.3 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain HA PF03457.14 GAM20902.1 - 2 8.8 16.4 56 4.2 0.0 8.3 10 1 1 11 11 10 0 Helicase associated domain Podoplanin PF05808.11 GAM20904.1 - 0.0033 17.6 1.3 0.0077 16.3 1.3 1.6 1 0 0 1 1 1 1 Podoplanin DUF5326 PF17260.2 GAM20904.1 - 0.1 12.7 3.0 0.26 11.4 3.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5326) SKG6 PF08693.10 GAM20904.1 - 1.1 8.7 7.2 2.8 7.4 7.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PTP_tm PF18861.1 GAM20904.1 - 2 8.4 7.5 0.95 9.4 4.5 2.0 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4006 PF13179.6 GAM20904.1 - 3 7.8 5.1 0.86 9.6 0.1 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF4006) Ank_5 PF13857.6 GAM20905.1 - 1.2e-09 38.2 2.8 0.0018 18.5 0.2 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM20905.1 - 4.3e-07 30.4 2.2 1.7e-05 25.3 0.6 2.6 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20905.1 - 5.8e-06 26.7 4.1 0.00056 20.4 0.7 3.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20905.1 - 7.6e-05 22.8 1.8 0.13 12.9 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 GAM20906.1 - 4.3e-46 155.4 19.0 1.7e-08 34.9 0.1 6.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20906.1 - 8.1e-33 112.4 8.7 1.2e-06 28.9 0.5 9.2 3 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20906.1 - 7.8e-30 102.6 9.3 0.014 15.7 0.0 12.0 2 1 10 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20906.1 - 1.4e-23 80.4 4.6 0.6 10.8 0.0 11.7 11 1 1 12 12 11 5 Ankyrin repeat DUF5049 PF16468.5 GAM20906.1 - 1.1e-06 28.4 3.8 6.8 6.7 0.0 7.8 8 3 1 9 9 9 2 Domain of unknown function (DUF5049) Ank PF00023.30 GAM20906.1 - 1.8e-06 28.1 1.3 71 4.1 0.0 8.7 5 3 1 6 6 6 0 Ankyrin repeat DUF3447 PF11929.8 GAM20906.1 - 5.4e-05 23.1 3.1 1.9 8.5 0.0 5.0 1 1 5 6 6 6 2 Domain of unknown function (DUF3447) VHL_C PF17211.3 GAM20906.1 - 0.025 14.6 0.0 14 5.8 0.0 4.2 5 0 0 5 5 5 0 VHL box domain HTH_22 PF13309.6 GAM20906.1 - 0.052 13.6 0.0 6.3 7.0 0.0 3.9 4 1 0 4 4 4 0 HTH domain DUF4261 PF14080.6 GAM20906.1 - 0.092 12.9 0.1 10 6.3 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4261) Xylo_C PF12529.8 GAM20906.1 - 0.14 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Xylosyltransferase C terminal APP_Cu_bd PF12924.7 GAM20906.1 - 0.39 11.5 3.9 5.1 7.9 0.1 4.2 5 0 0 5 5 5 0 Copper-binding of amyloid precursor, CuBD Rap_GAP PF02145.15 GAM20907.1 - 2.5e-59 199.9 0.4 4.6e-59 199.1 0.4 1.4 1 0 0 1 1 1 1 Rap/ran-GAP CNH PF00780.22 GAM20907.1 - 9.7e-36 123.8 0.0 1.7e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 CNH domain Metallothi_Euk2 PF12809.7 GAM20909.1 - 0.019 15.3 4.5 0.019 15.3 4.5 2.8 3 1 1 4 4 4 0 Eukaryotic metallothionein DUF902 PF06001.13 GAM20909.1 - 0.09 13.3 2.4 0.09 13.3 2.4 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF902) IBN_N PF03810.19 GAM20910.1 - 0.0034 17.3 0.3 0.02 14.8 0.2 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Bac_DnaA_C PF08299.11 GAM20910.1 - 0.037 14.1 0.5 0.21 11.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein helix-turn-helix GTP_EFTU PF00009.27 GAM20911.1 - 1.1e-53 181.7 0.3 1.7e-53 181.1 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAM20911.1 - 1.3e-18 66.8 0.0 3.7e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAM20911.1 - 2.9e-07 30.8 1.5 2.9e-07 30.8 1.5 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM20911.1 - 1.2e-06 28.6 0.1 2.8e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 GAM20911.1 - 0.0018 17.6 0.1 0.0038 16.6 0.1 1.5 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 GAM20911.1 - 0.0027 17.2 0.0 0.0027 17.2 0.0 2.6 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GAM20911.1 - 0.0076 15.8 0.1 0.062 12.8 0.1 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B EFG_II PF14492.6 GAM20911.1 - 0.015 15.4 0.2 0.043 13.9 0.2 1.8 1 0 0 1 1 1 0 Elongation Factor G, domain II Dynamin_N PF00350.23 GAM20911.1 - 0.015 15.3 0.0 0.32 11.0 0.0 2.3 1 1 1 2 2 2 0 Dynamin family MeaB PF03308.16 GAM20911.1 - 0.049 12.6 0.2 6.9 5.6 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 GAM20911.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PWWP PF00855.17 GAM20912.1 - 1.7e-08 34.7 0.0 1.7e-08 34.7 0.0 3.7 5 1 0 5 5 5 1 PWWP domain Mei5_like PF17021.5 GAM20912.1 - 0.46 10.5 0.0 0.46 10.5 0.0 3.0 3 0 0 3 3 3 0 Putative double-strand recombination repair-like FMO-like PF00743.19 GAM20913.1 - 9.5e-59 199.2 0.0 1.4e-58 198.7 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM20913.1 - 1.9e-20 73.3 0.0 2.8e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM20913.1 - 4.3e-19 68.8 0.0 3.2e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM20913.1 - 9.4e-11 41.4 0.5 9.9e-09 34.8 0.2 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAM20913.1 - 3.1e-09 37.0 0.1 1.2e-07 31.8 0.1 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAM20913.1 - 2.2e-06 27.8 0.0 4.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM20913.1 - 2.2e-06 28.1 0.0 0.02 15.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAM20913.1 - 3.4e-06 26.6 0.0 0.038 13.3 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 GAM20913.1 - 1.6e-05 24.7 0.0 0.33 10.5 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 GAM20913.1 - 0.00026 20.3 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 GAM20913.1 - 0.00091 18.0 0.0 0.0021 16.8 0.0 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 GAM20913.1 - 0.0013 17.9 0.0 0.26 10.3 0.0 2.1 1 1 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 GAM20913.1 - 0.0018 17.6 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 GAM20913.1 - 0.045 12.8 0.0 0.29 10.2 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein Prenylcys_lyase PF07156.14 GAM20913.1 - 0.073 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Prenylcysteine lyase COPIIcoated_ERV PF07970.12 GAM20914.1 - 7.2e-84 281.1 0.4 1.1e-83 280.4 0.4 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAM20914.1 - 5.3e-31 106.8 0.2 5.3e-31 106.8 0.2 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) BEN PF10523.9 GAM20915.1 - 0.041 14.1 0.0 1.9 8.7 0.0 2.9 3 0 0 3 3 3 0 BEN domain GalKase_gal_bdg PF10509.9 GAM20919.1 - 1.3e-22 79.1 0.0 2.5e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 GAM20919.1 - 2.7e-14 53.3 0.2 1.9e-13 50.6 0.0 2.3 1 1 1 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GAM20919.1 - 3.2e-10 40.1 0.2 3.2e-10 40.1 0.2 3.0 3 0 0 3 3 3 1 GHMP kinases N terminal domain FLgD_tudor PF13861.6 GAM20919.1 - 0.13 12.5 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 FlgD Tudor-like domain LRV PF01816.17 GAM20920.1 - 1.4 9.5 3.9 0.91 10.1 0.5 2.5 2 1 1 3 3 3 0 Leucine rich repeat variant Glutaminase PF04960.15 GAM20921.1 - 8e-26 90.9 1.2 3.8e-25 88.7 1.2 1.9 1 1 0 1 1 1 1 Glutaminase SH3_1 PF00018.28 GAM20921.1 - 4e-21 74.3 4.1 4.2e-13 48.7 0.3 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 GAM20921.1 - 2.4e-18 65.7 2.7 5.6e-09 35.7 0.4 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 GAM20921.1 - 6.1e-18 64.3 0.3 4e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain CS PF04969.16 GAM20921.1 - 1.5e-06 29.2 0.2 3.2e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 CS domain Ras PF00071.22 GAM20922.1 - 7.4e-52 175.2 0.0 9e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM20922.1 - 2.9e-24 85.6 0.0 4.3e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM20922.1 - 3.3e-11 43.0 0.0 4.2e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM20922.1 - 8.7e-07 28.7 0.0 6e-06 25.9 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM20922.1 - 0.0019 18.3 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ctr PF04145.15 GAM20923.1 - 2.1e-26 93.3 5.4 3.1e-26 92.8 5.4 1.2 1 0 0 1 1 1 1 Ctr copper transporter family YtxC PF08812.11 GAM20923.1 - 0.026 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 YtxC-like family TMEM135_C_rich PF15982.5 GAM20924.1 - 0.00086 19.9 8.0 0.0065 17.1 0.9 2.3 2 1 0 2 2 2 2 N-terminal cysteine-rich region of Transmembrane protein 135 TMEM132D_C PF15706.5 GAM20924.1 - 0.05 13.4 0.6 0.8 9.5 0.0 2.5 2 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term IP_trans PF02121.18 GAM20925.1 - 7.1e-112 372.9 1.2 8.1e-112 372.8 1.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Cytokin_check_N PF10407.9 GAM20926.1 - 0.11 12.5 0.0 0.46 10.5 0.0 2.1 1 1 1 2 2 2 0 Cdc14 phosphatase binding protein N-terminus EF-hand_1 PF00036.32 GAM20927.1 - 1.9e-12 45.8 0.4 4.6e-05 22.7 0.4 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAM20927.1 - 3e-12 45.4 0.3 2e-06 27.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAM20927.1 - 1e-09 38.1 0.6 9.5e-08 31.8 0.0 1.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 GAM20927.1 - 3e-09 37.2 0.1 3.4e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GAM20927.1 - 2.7e-06 26.6 0.6 0.00082 18.8 0.2 2.3 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 GAM20927.1 - 0.00032 21.0 0.0 0.00039 20.7 0.0 1.0 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GAM20927.1 - 0.00071 19.8 0.0 0.00095 19.4 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain ELO PF01151.18 GAM20928.1 - 2.5e-41 141.9 5.3 1e-27 97.2 1.1 2.0 2 0 0 2 2 2 2 GNS1/SUR4 family Chordopox_G3 PF06129.12 GAM20929.1 - 5.7 7.7 8.5 31 5.3 5.1 2.9 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Na_Ca_ex PF01699.24 GAM20930.1 - 1.8e-15 57.2 42.0 1.2e-11 44.8 20.3 4.2 3 2 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 GAM20930.1 - 5.9e-13 49.3 11.5 5.9e-13 49.3 11.5 4.9 5 0 0 5 5 5 2 Inner membrane component domain Androgen_recep PF02166.16 GAM20930.1 - 0.22 10.3 7.4 0.33 9.7 7.4 1.1 1 0 0 1 1 1 0 Androgen receptor Tmpp129 PF10272.9 GAM20930.1 - 0.41 9.9 3.3 16 4.6 0.0 3.1 3 0 0 3 3 3 0 Putative transmembrane protein precursor TAFII55_N PF04658.13 GAM20932.1 - 2.4e-27 95.6 0.1 2.4e-27 95.6 0.1 2.9 4 0 0 4 4 4 1 TAFII55 protein conserved region FapA PF03961.13 GAM20932.1 - 0.039 12.6 2.4 0.073 11.7 2.4 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Vps51 PF08700.11 GAM20932.1 - 0.061 13.4 0.4 0.061 13.4 0.4 2.3 2 0 0 2 2 2 0 Vps51/Vps67 S6OS1 PF15676.5 GAM20932.1 - 0.53 8.7 12.4 1.8 7.0 3.0 2.6 2 0 0 2 2 2 0 Six6 opposite strand transcript 1 family AA_permease_2 PF13520.6 GAM20933.1 - 1e-45 156.4 49.8 1e-45 156.4 49.8 1.7 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 GAM20933.1 - 3.9e-41 141.1 42.1 3.9e-41 141.1 42.1 1.8 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 GAM20933.1 - 1.4e-18 66.6 2.9 1.4e-18 66.6 2.9 3.5 4 1 0 4 4 4 1 C-terminus of AA_permease Spore_permease PF03845.13 GAM20933.1 - 0.0014 17.5 20.5 0.0014 17.5 20.5 2.8 3 1 0 3 3 3 1 Spore germination protein Ammonium_transp PF00909.21 GAM20934.1 - 3e-96 322.6 36.7 3.5e-96 322.3 36.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family IF4E PF01652.18 GAM20935.1 - 1.2e-39 135.7 0.1 2.4e-39 134.7 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Thioredoxin_8 PF13905.6 GAM20937.1 - 0.061 13.6 0.1 0.33 11.3 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like TSA PF03249.13 GAM20937.1 - 0.067 12.0 1.0 0.089 11.6 1.0 1.1 1 0 0 1 1 1 0 Type specific antigen DUF2967 PF11179.8 GAM20937.1 - 0.082 11.0 1.9 0.11 10.6 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) MFAP1 PF06991.11 GAM20937.1 - 0.18 11.7 5.1 0.25 11.1 5.1 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing DUF3295 PF11702.8 GAM20937.1 - 0.63 9.3 10.9 0.87 8.9 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Cwf_Cwc_15 PF04889.12 GAM20937.1 - 2.1 8.0 12.5 2.9 7.6 12.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 GAM20937.1 - 3.8 7.5 7.9 6.2 6.8 7.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal ThiF PF00899.21 GAM20938.1 - 5.2e-19 68.6 0.0 1.3e-18 67.3 0.0 1.7 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 GAM20938.1 - 6.5e-07 29.4 0.0 0.00031 20.9 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle NUDIX PF00293.28 GAM20939.1 - 3e-14 53.2 0.0 5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Zn-C2H2_12 PF18112.1 GAM20939.1 - 0.0048 17.3 4.8 0.026 15.0 0.3 2.5 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 GAM20939.1 - 0.11 12.9 1.4 0.64 10.4 1.4 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 GAM20939.1 - 0.11 12.4 2.4 4.4 7.3 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Vps54_N PF10475.9 GAM20940.1 - 8.4e-73 245.2 13.9 8.4e-73 245.2 13.9 2.5 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 GAM20940.1 - 4e-62 210.0 0.7 4e-62 210.0 0.7 3.4 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) DUF3510 PF12022.8 GAM20940.1 - 0.0016 18.8 2.4 0.0077 16.6 0.0 3.3 3 2 0 3 3 3 1 Domain of unknown function (DUF3510) DUF3010 PF11215.8 GAM20940.1 - 0.0064 16.8 1.4 0.018 15.4 1.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3010) FANCI_S2 PF14676.6 GAM20940.1 - 0.36 11.1 8.3 0.96 9.7 0.3 2.8 2 0 0 2 2 2 0 FANCI solenoid 2 DUF4745 PF15923.5 GAM20940.1 - 1.1 9.3 5.3 0.9 9.5 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4745) Ank_2 PF12796.7 GAM20941.1 - 3.5e-31 107.6 31.1 1e-10 42.0 2.0 6.2 1 1 7 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM20941.1 - 1.9e-17 63.3 17.5 0.001 19.6 0.1 9.0 7 4 1 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20941.1 - 2.5e-17 62.7 18.7 1.8e-05 24.9 0.4 10.0 6 3 5 11 11 11 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20941.1 - 1.1e-11 43.8 19.8 2.7 8.8 0.0 11.8 10 4 3 13 13 13 4 Ankyrin repeat DUF3447 PF11929.8 GAM20941.1 - 5.1e-09 36.0 3.9 0.36 10.8 0.1 5.9 2 2 5 7 7 7 5 Domain of unknown function (DUF3447) Ank PF00023.30 GAM20941.1 - 0.00043 20.6 18.5 0.49 10.9 0.3 7.2 4 3 2 6 6 6 2 Ankyrin repeat DUF1843 PF08898.10 GAM20941.1 - 0.6 10.7 2.1 1.1e+02 3.4 0.1 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF1843) WH2 PF02205.20 GAM20942.1 - 3.9e-07 29.7 0.6 0.43 10.5 0.0 3.3 3 0 0 3 3 3 3 WH2 motif bVLRF1 PF18826.1 GAM20943.1 - 3.4e-42 143.8 0.3 3.5e-41 140.5 0.0 2.8 3 0 0 3 3 3 1 bacteroidetes VLRF1 release factor Ank_2 PF12796.7 GAM20943.1 - 6.5e-15 55.5 0.0 2.2e-10 41.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) VATC PF18716.1 GAM20943.1 - 3e-11 43.0 4.6 1.8e-10 40.5 0.9 2.4 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank_5 PF13857.6 GAM20943.1 - 1.5e-09 37.9 0.0 2e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM20943.1 - 1.2e-07 32.1 0.0 0.0014 19.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM20943.1 - 3.4e-07 30.0 0.0 0.011 16.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAM20943.1 - 7e-05 23.1 0.0 0.015 15.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Cwf_Cwc_15 PF04889.12 GAM20943.1 - 0.93 9.2 29.3 0.089 12.5 0.5 3.4 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein RR_TM4-6 PF06459.12 GAM20943.1 - 5.9 6.6 19.1 4.1 7.1 10.4 2.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SAGA-Tad1 PF12767.7 GAM20943.1 - 8.4 6.1 17.7 1 9.1 6.4 2.9 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Asp-B-Hydro_N PF05279.11 GAM20943.1 - 9.3 6.2 20.9 1.6 8.7 10.9 2.4 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region PGA_cap PF09587.10 GAM20943.1 - 9.4 5.6 6.5 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap Pkinase_Tyr PF07714.17 GAM20944.1 - 1.3e-50 172.1 0.0 2.2e-50 171.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM20944.1 - 6.5e-46 156.8 0.0 1.8e-45 155.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAM20944.1 - 6.9e-05 22.9 0.0 0.00077 19.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM20944.1 - 0.0028 16.5 0.1 0.0028 16.5 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAM20944.1 - 0.0095 15.3 0.0 0.022 14.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like F-box-like PF12937.7 GAM20944.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 GAM20944.1 - 0.022 14.6 0.3 0.067 13.1 0.3 1.8 1 0 0 1 1 1 0 F-box domain Kdo PF06293.14 GAM20944.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SpoIIID PF12116.8 GAM20944.1 - 0.15 12.1 0.1 0.66 10.1 0.0 2.0 2 0 0 2 2 2 0 Stage III sporulation protein D PIP49_C PF12260.8 GAM20944.1 - 0.15 11.6 0.7 0.48 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 LRR_4 PF12799.7 GAM20945.1 - 3.5e-06 27.2 7.1 0.17 12.4 1.1 5.7 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 GAM20945.1 - 0.0008 19.7 14.7 0.0022 18.3 14.7 1.8 1 0 0 1 1 1 1 EGF-like domain Epiglycanin_C PF14654.6 GAM20945.1 - 0.019 15.0 0.2 0.053 13.6 0.2 1.8 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region I-EGF_1 PF18372.1 GAM20945.1 - 0.02 15.0 6.7 0.047 13.8 6.7 1.6 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Phage_holin_2_1 PF04971.12 GAM20945.1 - 0.024 14.6 0.1 0.23 11.5 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage P21 holin S LRR_8 PF13855.6 GAM20945.1 - 0.028 14.2 1.4 5.3 6.9 0.4 3.9 4 1 0 4 4 4 0 Leucine rich repeat BPD_transp_1 PF00528.22 GAM20945.1 - 0.048 13.4 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component EB PF01683.18 GAM20945.1 - 0.12 12.7 8.3 0.3 11.4 8.3 1.6 1 0 0 1 1 1 0 EB module EGF PF00008.27 GAM20945.1 - 0.17 12.2 7.7 0.4 11.0 7.7 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 GAM20945.1 - 0.21 12.3 9.7 0.96 10.2 9.7 2.3 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 GAM20945.1 - 0.78 9.9 12.3 2 8.5 12.3 1.7 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 GAM20946.1 - 0.0091 16.3 12.0 0.0091 16.3 12.0 2.2 3 0 0 3 3 3 1 EGF-like domain VERL PF11386.8 GAM20946.1 - 0.066 13.4 0.2 6.7 7.0 0.1 3.2 3 0 0 3 3 3 0 Vitelline envelope receptor for lysin cEGF PF12662.7 GAM20946.1 - 0.3 11.0 2.0 13 5.8 0.7 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like EB PF01683.18 GAM20946.1 - 0.35 11.2 6.3 0.86 9.9 6.3 1.6 1 0 0 1 1 1 0 EB module Vps36-NZF-N PF16988.5 GAM20946.1 - 0.49 9.8 4.5 0.42 10.1 0.2 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Aa_trans PF01490.18 GAM20947.1 - 2.3e-14 52.9 43.7 1.8e-08 33.5 34.1 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein TPP_enzyme_N PF02776.18 GAM20948.1 - 4.7e-40 137.0 0.0 3.2e-39 134.3 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAM20948.1 - 7.9e-31 106.6 0.0 1.3e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GAM20948.1 - 6.2e-19 68.3 0.2 1.9e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GpcrRhopsn4 PF10192.9 GAM20949.1 - 9.5e-50 169.4 32.8 9.5e-50 169.4 32.8 1.6 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain DUF2427 PF10348.9 GAM20949.1 - 0.015 15.1 2.1 0.015 15.1 2.1 3.8 3 1 1 5 5 5 0 Domain of unknown function (DUF2427) Pkinase PF00069.25 GAM20950.1 - 1.7e-76 257.1 0.0 2e-76 256.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM20950.1 - 5.4e-41 140.6 0.0 6.7e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM20950.1 - 1.1e-07 31.4 0.0 3.8e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 GAM20950.1 - 0.0053 16.4 0.0 0.0098 15.5 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAM20950.1 - 0.0089 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM20950.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family RasGEF PF00617.19 GAM20951.1 - 1.1e-53 182.1 0.2 1.1e-53 182.1 0.2 2.5 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 GAM20951.1 - 1.9e-18 66.6 2.0 1.8e-16 60.3 0.5 5.1 6 1 0 6 6 6 2 RasGEF N-terminal motif F-box-like PF12937.7 GAM20951.1 - 9.4e-14 51.0 3.0 6.3e-07 29.2 1.3 3.1 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 GAM20951.1 - 2.8e-08 33.4 3.6 0.00022 21.0 0.7 3.4 3 0 0 3 3 3 2 F-box domain Mucin PF01456.17 GAM20951.1 - 0.002 18.1 6.6 0.002 18.1 6.6 6.3 5 1 2 7 7 7 1 Mucin-like glycoprotein DUF1149 PF06619.11 GAM20951.1 - 0.25 11.6 4.0 0.41 11.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1149) SdrD_B PF17210.3 GAM20953.1 - 4.7e-11 42.9 2.8 5.3e-11 42.7 2.8 1.1 1 0 0 1 1 1 1 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM20953.1 - 0.0016 18.7 0.1 0.0025 18.0 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 GAM20953.1 - 0.0049 17.2 1.3 0.0066 16.8 1.3 1.3 1 0 0 1 1 1 1 Prealbumin-like fold domain SAPS PF04499.15 GAM20956.1 - 2.1e-06 26.8 0.2 2.1e-06 26.8 0.2 7.2 4 1 2 6 6 6 3 SIT4 phosphatase-associated protein Hint_2 PF13403.6 GAM20957.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Hint domain SLC12 PF03522.15 GAM20957.1 - 0.21 10.6 8.6 0.39 9.7 8.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 GAM20957.1 - 0.32 9.2 16.4 0.45 8.7 16.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 GAM20957.1 - 0.52 9.0 9.4 1 8.1 9.4 1.5 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 GAM20957.1 - 0.78 8.4 11.7 1.5 7.4 11.7 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1840 PF08895.11 GAM20957.1 - 1.1 9.7 7.2 2.5 8.5 6.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) Lyase_8 PF02278.18 GAM20958.1 - 1e-61 208.6 6.0 1e-61 208.6 6.0 2.1 3 0 0 3 3 3 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_C PF02884.17 GAM20958.1 - 3.6e-16 59.4 0.8 1.4e-15 57.5 0.8 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Lyase_8_N PF08124.11 GAM20958.1 - 5e-08 32.2 3.6 1.1e-07 31.2 3.6 1.5 1 1 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Ank_2 PF12796.7 GAM20960.1 - 0.29 11.7 14.8 6.4 7.4 0.0 7.6 8 1 0 8 8 8 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM20960.1 - 4.3 8.2 16.7 2.8e+02 2.7 0.1 9.8 12 0 0 12 12 12 0 Ankyrin repeat DNA_pol_A_exo1 PF01612.20 GAM20961.1 - 3.3e-44 150.7 0.1 7e-44 149.6 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 GAM20961.1 - 3.1e-14 52.7 0.0 6.7e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Ras PF00071.22 GAM20962.1 - 5.6e-61 204.9 0.1 6.4e-61 204.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM20962.1 - 4.1e-34 117.4 0.0 1.5e-33 115.5 0.0 1.7 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM20962.1 - 3.2e-11 43.0 0.1 3.9e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM20962.1 - 4.2e-05 23.0 0.0 5.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAM20962.1 - 8.3e-05 22.5 0.1 0.063 13.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM20962.1 - 0.00045 20.3 0.0 0.00087 19.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM20962.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAM20962.1 - 0.019 15.4 0.1 0.034 14.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain MukE PF04288.13 GAM20963.1 - 0.14 11.1 0.1 0.23 10.4 0.1 1.3 1 0 0 1 1 1 0 MukE-like family RRM_1 PF00076.22 GAM20965.1 - 1.5e-15 56.7 0.3 2.6e-15 56.0 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TROVE PF05731.11 GAM20965.1 - 0.067 12.2 2.8 0.09 11.8 2.8 1.1 1 0 0 1 1 1 0 TROVE domain SOG2 PF10428.9 GAM20965.1 - 0.89 8.7 11.6 1.3 8.1 11.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RRM_1 PF00076.22 GAM20966.1 - 1.9e-07 30.8 0.0 3.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V-SNARE PF05008.15 GAM20967.1 - 0.00034 20.9 3.8 0.00034 20.9 3.8 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 GAM20967.1 - 0.0012 19.1 3.1 0.003 17.8 1.6 2.3 3 0 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAM20967.1 - 0.0012 18.7 2.3 0.0067 16.3 0.6 2.3 2 1 0 2 2 2 1 Sec20 Synaptobrevin PF00957.21 GAM20967.1 - 0.0059 16.4 5.9 0.0059 16.4 5.9 2.3 2 0 0 2 2 2 1 Synaptobrevin LAP1C PF05609.12 GAM20967.1 - 0.0096 15.1 1.0 0.011 14.9 1.0 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) DUF3533 PF12051.8 GAM20967.1 - 0.036 13.0 0.4 0.046 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) MtrF PF09472.10 GAM20967.1 - 0.039 13.3 0.9 0.083 12.3 0.9 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SNARE PF05739.19 GAM20967.1 - 0.1 12.6 4.1 0.18 11.9 1.9 2.3 2 0 0 2 2 2 0 SNARE domain Tup_N PF08581.10 GAM20967.1 - 0.18 12.2 14.3 1.2 9.5 0.4 3.3 3 0 0 3 3 3 0 Tup N-terminal XhlA PF10779.9 GAM20967.1 - 0.22 11.7 7.6 5.3 7.3 0.4 3.4 3 0 0 3 3 3 0 Haemolysin XhlA DUF4199 PF13858.6 GAM20967.1 - 0.25 11.7 5.5 0.079 13.4 2.4 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF4199) Orf78 PF06024.12 GAM20967.1 - 0.38 11.1 1.9 0.53 10.6 0.9 1.8 1 1 1 2 2 2 0 Orf78 (ac78) DUF2408 PF10303.9 GAM20967.1 - 0.4 11.2 4.7 1.4 9.4 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) EMP24_GP25L PF01105.24 GAM20967.1 - 1.7 8.5 6.8 0.72 9.8 1.2 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD MCU PF04678.13 GAM20967.1 - 1.9 8.6 8.7 0.46 10.6 1.6 2.5 1 1 1 3 3 3 0 Mitochondrial calcium uniporter Vpu PF00558.19 GAM20967.1 - 2.1 8.2 8.6 0.55 10.0 4.8 2.1 2 0 0 2 2 2 0 Vpu protein FeoB_associated PF12669.7 GAM20967.1 - 4.1 7.9 7.4 7.2 7.1 7.4 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SlyX PF04102.12 GAM20967.1 - 4.4 8.0 6.4 2 9.1 1.4 2.9 3 1 1 4 4 4 0 SlyX HisKA_3 PF07730.13 GAM20967.1 - 5.1 7.7 7.6 2.9 8.5 0.7 3.5 2 2 3 5 5 5 0 Histidine kinase Uso1_p115_C PF04871.13 GAM20967.1 - 5.3 7.4 14.5 0.23 11.8 3.6 2.7 1 1 2 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2207 PF09972.9 GAM20967.1 - 5.3 5.7 7.9 70 2.0 7.9 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CCDC-167 PF15188.6 GAM20967.1 - 6.7 7.1 10.7 8 6.9 0.5 3.2 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 167 LRR_6 PF13516.6 GAM20968.1 - 3.5e-23 79.6 59.6 0.012 15.6 0.0 14.0 14 0 0 14 14 14 11 Leucine Rich repeat LRR_4 PF12799.7 GAM20968.1 - 0.0019 18.5 56.6 0.043 14.3 3.9 9.9 6 2 5 11 11 11 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 GAM20968.1 - 0.0032 17.3 0.4 0.27 11.1 0.1 2.8 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 GAM20968.1 - 0.0065 16.9 35.4 7.4 7.6 1.8 11.1 12 1 0 12 12 12 2 Leucine Rich Repeat LRR_8 PF13855.6 GAM20968.1 - 2.6 7.9 50.8 1.7 8.5 6.6 9.2 5 3 3 8 8 8 0 Leucine rich repeat TPR_1 PF00515.28 GAM20969.1 - 5.9e-63 206.3 20.3 7.2e-08 31.9 0.1 9.8 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAM20969.1 - 5.5e-52 169.7 17.6 1.6e-05 24.7 0.0 9.8 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAM20969.1 - 5e-44 144.8 20.2 1.4e-05 24.9 0.0 10.9 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 GAM20969.1 - 6.3e-32 107.6 17.4 0.00013 22.1 0.1 11.4 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 GAM20969.1 - 6.6e-27 91.9 0.0 0.03 15.1 0.0 8.8 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 GAM20969.1 - 5.1e-26 90.8 13.3 8.6e-06 26.0 1.1 7.3 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAM20969.1 - 1.4e-25 89.6 0.0 3.8e-05 24.3 0.0 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAM20969.1 - 2.8e-23 82.2 3.7 0.0018 18.7 0.5 6.5 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 GAM20969.1 - 3.1e-22 78.0 31.5 3.4e-05 23.4 1.4 10.2 4 3 6 10 10 10 8 TPR repeat TPR_7 PF13176.6 GAM20969.1 - 4.2e-22 76.5 7.7 0.27 11.4 0.0 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_6 PF13174.6 GAM20969.1 - 4.1e-19 67.9 13.8 0.0053 17.3 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAM20969.1 - 6.4e-16 58.3 0.4 0.003 17.7 0.3 7.0 2 1 5 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM20969.1 - 2.2e-12 47.0 15.7 1e-05 25.6 1.1 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GAM20969.1 - 3.1e-08 33.2 7.8 0.0056 15.9 2.9 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 GAM20969.1 - 2.1e-07 31.2 0.3 1.6 9.1 0.0 6.5 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 GAM20969.1 - 1.4e-06 28.2 5.5 0.1 12.3 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat-like domain ChAPs PF09295.10 GAM20969.1 - 9.9e-06 24.8 1.3 0.079 11.9 0.0 3.6 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 GAM20969.1 - 0.0031 18.0 0.4 8.9 6.7 0.0 3.7 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 GAM20969.1 - 0.011 15.6 4.3 11 6.1 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ORC3_N PF07034.11 GAM20970.1 - 2e-27 96.2 2.3 3.2e-25 88.9 2.3 2.4 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 GAM20970.1 - 8.8e-19 68.0 5.2 4.4e-11 43.0 0.0 3.3 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal zf-RING_7 PF02591.15 GAM20970.1 - 0.054 13.7 5.5 0.6 10.3 2.1 2.9 2 0 0 2 2 2 0 C4-type zinc ribbon domain FYVE_2 PF02318.16 GAM20970.1 - 0.2 11.9 9.9 0.69 10.1 9.9 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger zf-CW PF07496.15 GAM20970.1 - 0.44 10.6 6.3 1.7 8.7 6.3 2.0 1 0 0 1 1 1 0 CW-type Zinc Finger CENP-B_dimeris PF09026.10 GAM20971.1 - 0.0042 17.4 8.7 0.012 15.9 8.7 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Ank_2 PF12796.7 GAM20971.1 - 0.02 15.4 15.2 0.44 11.2 0.0 7.4 9 2 1 10 10 10 0 Ankyrin repeats (3 copies) RNA_pol_3_Rpc31 PF11705.8 GAM20971.1 - 0.29 11.4 6.5 0.5 10.6 6.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 GAM20971.1 - 0.84 8.9 6.2 1.6 8.0 6.2 1.4 1 0 0 1 1 1 0 NOA36 protein DUF758 PF05527.11 GAM20972.1 - 5.7e-35 120.9 1.3 9.9e-35 120.1 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF758) PH PF00169.29 GAM20972.1 - 1.3e-07 32.1 0.0 2.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 GAM20972.1 - 0.00052 20.4 0.2 0.0012 19.2 0.2 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain p450 PF00067.22 GAM20972.1 - 0.023 13.4 0.1 0.034 12.9 0.1 1.2 1 0 0 1 1 1 0 Cytochrome P450 DUF150 PF02576.17 GAM20972.1 - 0.089 13.2 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 RimP N-terminal domain SET PF00856.28 GAM20973.1 - 1.1e-14 55.2 0.5 8.2e-14 52.3 0.5 2.2 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 GAM20973.1 - 1.6e-07 30.9 0.4 0.034 14.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM20973.1 - 3.9e-05 23.3 1.4 0.12 12.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-MYND PF01753.18 GAM20973.1 - 4.2e-05 23.5 0.9 4.2e-05 23.5 0.9 2.5 3 0 0 3 3 3 1 MYND finger TPR_16 PF13432.6 GAM20973.1 - 0.015 15.9 0.0 0.46 11.2 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM20973.1 - 0.11 13.0 0.1 0.94 10.0 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM20973.1 - 0.12 12.6 0.6 10 6.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PSCyt3 PF07627.11 GAM20973.1 - 8.9 6.7 7.3 14 6.1 0.8 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1588) Rab3-GTPase_cat PF13890.6 GAM20974.1 - 1.5e-42 145.0 1.4 1.5e-42 145.0 1.4 2.7 3 1 0 3 3 3 1 Rab3 GTPase-activating protein catalytic subunit TFIIA PF03153.13 GAM20974.1 - 0.51 10.3 18.3 0.42 10.6 4.9 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 GAM20974.1 - 4 7.7 5.9 8 6.7 0.4 2.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Pex14_N PF04695.13 GAM20974.1 - 9.7 6.8 15.8 0.73 10.5 3.2 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PH PF00169.29 GAM20975.1 - 6.9e-14 52.2 0.2 1.4e-12 48.0 0.2 2.4 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM20975.1 - 9.8e-08 32.2 0.1 0.0079 16.4 0.1 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 GAM20975.1 - 3.2e-06 27.5 0.5 6.2e-05 23.4 0.5 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_12 PF16457.5 GAM20975.1 - 0.00019 21.9 5.3 0.009 16.5 0.0 3.2 3 0 0 3 3 3 2 Pleckstrin homology domain Mcp5_PH PF12814.7 GAM20975.1 - 0.021 15.0 0.4 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Lactamase_B PF00753.27 GAM20976.1 - 1.9e-16 60.6 0.1 2.7e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM20976.1 - 0.0013 18.3 0.1 0.002 17.6 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain bZIP_Maf PF03131.17 GAM20976.1 - 0.19 12.3 2.0 19 5.9 0.5 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Glycos_transf_2 PF00535.26 GAM20978.1 - 2.3e-29 102.4 0.0 5.4e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_1 PF00534.20 GAM20978.1 - 2.7e-25 88.9 0.0 9.6e-25 87.1 0.0 2.0 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_tranf_2_2 PF10111.9 GAM20978.1 - 6.5e-20 71.7 0.1 1.3e-19 70.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_1_4 PF13692.6 GAM20978.1 - 1.8e-17 64.1 0.0 3.4e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tranf_2_3 PF13641.6 GAM20978.1 - 3.5e-09 36.9 0.0 7.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_4 PF13439.6 GAM20978.1 - 0.00019 21.5 0.0 0.0005 20.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 GAM20978.1 - 0.001 19.4 0.0 0.0034 17.7 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 GRDB PF07355.12 GAM20978.1 - 0.037 13.3 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) Glyco_tranf_2_4 PF13704.6 GAM20978.1 - 0.047 14.2 0.4 0.62 10.6 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Nepo_coat_N PF03689.15 GAM20978.1 - 0.073 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain Glyco_trans_2_3 PF13632.6 GAM20978.1 - 0.079 12.9 0.0 0.31 10.9 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family group 2 AlcCBM31 PF11606.8 GAM20979.1 - 0.013 15.6 0.4 5.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Family 31 carbohydrate binding protein CBM49 PF09478.10 GAM20979.1 - 0.02 15.2 0.1 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain CBM49 FNIP PF05725.12 GAM20980.1 - 1.5e-35 121.1 10.8 1.1e-09 38.3 1.3 6.9 4 1 4 9 9 9 7 FNIP Repeat F-box_5 PF18511.1 GAM20981.1 - 3.5e-05 23.3 0.2 5.7e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 F-box FNIP PF05725.12 GAM20981.1 - 0.07 13.3 0.6 8.7 6.6 0.2 2.6 1 1 0 2 2 2 0 FNIP Repeat FNIP PF05725.12 GAM20982.1 - 4.2e-68 225.3 47.1 1.7e-11 44.1 0.2 11.4 5 3 5 12 12 12 11 FNIP Repeat DUF1769 PF08588.10 GAM20982.1 - 0.21 11.8 1.6 9.4 6.5 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF1769) DUF773 PF05600.12 GAM20984.1 - 6e-121 404.7 17.6 6.9e-121 404.5 17.6 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 PspB PF06667.12 GAM20984.1 - 0.0045 17.0 2.3 0.016 15.2 2.3 1.9 1 0 0 1 1 1 1 Phage shock protein B Filament PF00038.21 GAM20984.1 - 0.013 15.1 11.5 0.026 14.1 6.4 2.3 2 0 0 2 2 2 0 Intermediate filament protein DUF4535 PF15054.6 GAM20984.1 - 0.016 14.9 3.2 0.022 14.5 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4535) TMF_DNA_bd PF12329.8 GAM20984.1 - 0.19 11.8 15.4 2.5 8.1 5.7 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1043 PF06295.12 GAM20984.1 - 0.53 10.3 12.3 1.3 9.0 2.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) THOC7 PF05615.13 GAM20984.1 - 0.63 10.3 8.8 13 6.1 5.2 2.6 2 0 0 2 2 2 0 Tho complex subunit 7 Sec8_exocyst PF04048.14 GAM20984.1 - 0.86 9.5 13.2 3.6 7.5 0.9 2.9 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain LMBR1 PF04791.16 GAM20984.1 - 0.96 8.3 6.1 6.1 5.6 1.0 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein CREPT PF16566.5 GAM20984.1 - 1.4 9.1 14.1 7.6 6.7 0.9 3.1 2 2 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DivIVA PF05103.13 GAM20984.1 - 1.8 8.7 8.4 1.9 8.6 0.7 2.7 2 1 1 3 3 3 0 DivIVA protein DUF4446 PF14584.6 GAM20984.1 - 1.9 8.4 8.5 1.9 8.5 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) BRE1 PF08647.11 GAM20984.1 - 3.9 7.6 18.7 0.89 9.7 8.9 2.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase RabGAP-TBC PF00566.18 GAM20985.1 - 5.1e-51 173.4 0.6 8.3e-51 172.7 0.6 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HAMP PF00672.25 GAM20986.1 - 3.3e-53 177.9 14.0 7.9e-08 32.6 0.2 8.8 8 0 0 8 8 8 7 HAMP domain Response_reg PF00072.24 GAM20986.1 - 1e-43 148.1 0.3 4.3e-27 94.5 0.4 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 GAM20986.1 - 1.6e-31 109.1 0.9 7.5e-31 107.0 0.1 2.6 3 0 0 3 3 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAM20986.1 - 1.8e-19 69.5 1.3 1.3e-18 66.8 0.0 3.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain SpoIIID PF12116.8 GAM20986.1 - 3.5e-08 33.4 0.1 7.5 6.7 0.0 6.3 6 0 0 6 6 6 1 Stage III sporulation protein D Laminin_II PF06009.12 GAM20986.1 - 3.2e-07 30.4 32.0 0.11 12.5 0.1 7.6 7 0 0 7 7 7 4 Laminin Domain II GLE1 PF07817.13 GAM20986.1 - 1.2e-06 27.9 1.4 9.6 5.3 0.0 6.0 1 1 4 6 6 6 0 GLE1-like protein DUF3829 PF12889.7 GAM20986.1 - 9.4e-05 22.0 5.3 4.6 6.6 0.0 6.2 6 1 1 7 7 7 1 Protein of unknown function (DUF3829) DUF948 PF06103.11 GAM20986.1 - 0.00047 20.4 52.9 3.3 8.0 4.3 11.3 2 1 5 7 7 7 3 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 GAM20986.1 - 0.0025 18.0 10.9 59 4.0 0.1 8.3 6 2 4 10 10 10 0 Proteins of 100 residues with WXG DUF1843 PF08898.10 GAM20986.1 - 0.0047 17.4 0.4 57 4.3 0.0 5.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Tup_N PF08581.10 GAM20986.1 - 0.011 16.1 2.0 0.072 13.4 0.1 3.6 4 0 0 4 4 2 0 Tup N-terminal HTH_6 PF01418.17 GAM20986.1 - 0.011 15.7 1.7 36 4.4 0.0 5.5 6 0 0 6 6 6 0 Helix-turn-helix domain, rpiR family Baculo_ME53 PF06061.11 GAM20986.1 - 0.25 10.5 1.2 0.78 8.9 0.2 2.1 2 0 0 2 2 2 0 Baculoviridae ME53 Focal_AT PF03623.13 GAM20986.1 - 0.36 10.8 4.8 8.2 6.4 0.1 4.7 4 1 0 5 5 4 0 Focal adhesion targeting region CENP-F_leu_zip PF10473.9 GAM20986.1 - 0.49 10.4 9.7 1.2e+02 2.7 0.1 6.7 7 0 0 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1759 PF03564.15 GAM20986.1 - 0.86 9.5 6.0 1e+02 2.8 0.0 5.8 6 1 1 7 7 7 0 Protein of unknown function (DUF1759) DUF1186 PF06685.11 GAM20986.1 - 0.9 8.9 4.6 6.5 6.0 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1186) Bacillus_HBL PF05791.11 GAM20986.1 - 2 8.2 11.4 0.89 9.3 0.4 4.7 4 1 1 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) ApoLp-III PF07464.11 GAM20986.1 - 3.7 7.6 30.1 0.94 9.6 0.8 7.8 2 1 5 8 8 8 0 Apolipophorin-III precursor (apoLp-III) TSC22 PF01166.18 GAM20986.1 - 5.8 7.3 15.9 21 5.5 0.5 5.8 6 0 0 6 6 5 0 TSC-22/dip/bun family LSM PF01423.22 GAM20987.1 - 6.3e-19 67.4 1.7 8e-19 67.1 1.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM20987.1 - 0.021 14.9 0.1 0.029 14.5 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.8 GAM20987.1 - 0.098 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Candida_ALS_N PF11766.8 GAM20989.1 - 0.061 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding DUF2085 PF09858.9 GAM20989.1 - 0.95 10.0 12.3 0.37 11.3 2.3 3.2 2 2 1 3 3 3 0 Predicted membrane protein (DUF2085) VHP PF02209.19 GAM20990.1 - 3e-14 52.8 2.9 4.9e-14 52.1 2.9 1.4 1 0 0 1 1 1 1 Villin headpiece domain PV-1 PF06637.11 GAM20990.1 - 0.00029 19.8 2.6 0.00045 19.2 2.6 1.3 1 0 0 1 1 1 1 PV-1 protein (PLVAP) DUF4349 PF14257.6 GAM20990.1 - 0.06 12.8 0.2 0.1 12.1 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) bZIP_1 PF00170.21 GAM20990.1 - 0.12 12.5 3.3 0.22 11.7 3.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor SPX PF03105.19 GAM20990.1 - 0.12 12.2 7.9 0.15 12.0 7.9 1.1 1 0 0 1 1 1 0 SPX domain DivIC PF04977.15 GAM20990.1 - 0.15 11.9 2.3 0.31 10.8 2.3 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF5595 PF18077.1 GAM20990.1 - 0.16 12.1 1.2 0.27 11.3 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) FlaC_arch PF05377.11 GAM20990.1 - 0.4 11.1 2.4 0.31 11.5 0.5 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4551 PF15087.6 GAM20990.1 - 2.3 6.9 7.0 2.7 6.7 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hamartin PF04388.12 GAM20990.1 - 3.8 6.0 14.4 4.5 5.8 14.4 1.0 1 0 0 1 1 1 0 Hamartin protein Ank_4 PF13637.6 GAM20991.1 - 2.5e-52 174.6 26.8 3.2e-06 27.6 0.1 12.9 10 3 3 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM20991.1 - 4.7e-49 163.8 38.6 0.0001 22.5 0.0 18.5 4 3 16 20 20 20 16 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM20991.1 - 3.7e-47 158.8 32.3 4e-06 27.3 0.1 9.3 2 2 10 12 12 12 12 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM20991.1 - 3.1e-25 85.5 10.1 3.1 8.7 0.0 18.3 16 3 4 20 20 20 4 Ankyrin repeat DUF2790 PF10976.8 GAM20991.1 - 9.3e-06 25.6 6.6 4.9 7.2 0.0 6.9 5 1 1 7 7 7 2 Protein of unknown function (DUF2790) DUF5049 PF16468.5 GAM20991.1 - 1.4e-05 24.8 4.9 94 3.0 0.0 11.2 13 4 4 17 17 17 0 Domain of unknown function (DUF5049) TSLP PF15216.6 GAM20991.1 - 0.00098 19.4 16.2 21 5.4 0.5 8.4 3 3 8 11 11 11 0 Thymic stromal lymphopoietin ENTH PF01417.20 GAM20991.1 - 0.0012 18.9 0.6 18 5.4 0.0 5.7 5 2 0 5 5 5 1 ENTH domain Ank PF00023.30 GAM20991.1 - 0.0019 18.6 8.3 74 4.0 0.0 9.4 5 3 2 7 7 7 0 Ankyrin repeat DAP3 PF10236.9 GAM20992.1 - 5.2e-09 35.7 0.0 2e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 GAM20992.1 - 0.011 16.0 0.0 4.5 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 GAM20992.1 - 0.17 11.5 0.0 6.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DAP3 PF10236.9 GAM20993.1 - 0.00022 20.5 0.1 0.02 14.0 0.0 2.7 2 1 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 FSA_C PF10479.9 GAM20993.1 - 6.7 4.7 8.9 9.5 4.2 8.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DAP3 PF10236.9 GAM20994.1 - 0.0009 18.5 0.0 0.11 11.7 0.0 2.4 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Pet100 PF09803.9 GAM20995.1 - 1.4 9.5 3.7 0.63 10.6 0.5 2.1 2 1 0 2 2 2 0 Pet100 Pyr_redox_2 PF07992.14 GAM20997.1 - 3.1e-10 39.8 1.1 2.9e-05 23.4 0.2 3.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM20997.1 - 0.00018 20.8 1.1 0.92 8.7 0.0 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM20997.1 - 0.00066 19.0 0.0 0.24 10.6 0.0 2.7 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 GAM20997.1 - 0.0023 18.5 0.9 1.9 9.1 0.0 4.3 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAM20997.1 - 0.0055 17.1 0.0 3 8.3 0.0 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_9 PF13454.6 GAM20997.1 - 0.017 15.1 0.7 0.31 11.0 0.0 3.3 2 2 1 4 4 4 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 GAM20997.1 - 0.024 14.7 0.1 2.6 8.1 0.0 3.0 2 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 GAM20997.1 - 0.039 13.0 0.1 0.5 9.4 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAM20997.1 - 0.044 14.0 2.5 0.051 13.8 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FNIP PF05725.12 GAM20998.1 - 2.2e-107 351.0 18.4 1.4e-13 50.8 0.0 9.3 5 1 6 12 12 12 11 FNIP Repeat F-box_5 PF18511.1 GAM20998.1 - 0.0056 16.2 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 F-box DUF1168 PF06658.12 GAM20998.1 - 0.63 9.8 3.9 0.98 9.2 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Peptidase_C37 PF05416.12 GAM20998.1 - 3.7 5.9 5.4 3.7 5.9 4.3 1.5 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Aminotran_3 PF00202.21 GAM20999.1 - 8.9e-108 360.5 0.0 1.1e-107 360.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAM20999.1 - 5.1e-06 25.9 0.0 6.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 GAM21000.1 - 3.9e-20 72.1 24.5 5.9e-20 71.5 24.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 GAM21000.1 - 4.5e-17 61.7 15.9 7e-17 61.1 15.9 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein PUCC PF03209.15 GAM21000.1 - 1.2e-07 31.2 6.1 6e-07 28.8 6.1 1.9 1 1 0 1 1 1 1 PUCC protein BT1 PF03092.16 GAM21000.1 - 3.9e-05 22.1 0.1 3.9e-05 22.1 0.1 3.6 4 0 0 4 4 4 2 BT1 family SCNM1_acidic PF15805.5 GAM21000.1 - 0.47 10.2 2.1 0.83 9.4 2.1 1.3 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 DndE PF08870.11 GAM21001.1 - 0.15 12.3 0.5 0.5 10.6 0.1 2.0 2 0 0 2 2 2 0 DNA sulphur modification protein DndE Mob1_phocein PF03637.17 GAM21002.1 - 6.9e-57 192.1 0.4 8.1e-57 191.9 0.4 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_16 PF00722.21 GAM21003.1 - 0.0094 15.4 1.1 0.02 14.4 0.7 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 UMP1 PF05348.11 GAM21004.1 - 4.2e-22 78.6 0.2 5e-22 78.4 0.2 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 MitMem_reg PF13012.6 GAM21004.1 - 0.072 13.5 0.1 0.09 13.2 0.1 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Aldedh PF00171.22 GAM21005.1 - 3.6e-181 602.7 0.0 4.1e-181 602.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAM21005.1 - 0.059 12.8 0.0 0.87 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Ras PF00071.22 GAM21006.1 - 2.2e-50 170.4 0.2 2.6e-50 170.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM21006.1 - 1.3e-32 112.5 0.1 2.2e-32 111.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM21006.1 - 2.7e-13 49.8 0.0 3.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM21006.1 - 5.4e-05 22.8 0.0 0.0078 15.8 0.0 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAM21006.1 - 7.2e-05 22.2 0.2 9.3e-05 21.9 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM21006.1 - 0.00011 22.3 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAM21006.1 - 0.00079 18.9 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAM21006.1 - 0.011 15.7 0.1 3.7 7.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TFIID-18kDa PF02269.16 GAM21007.1 - 1.3e-29 102.0 0.8 1.9e-29 101.5 0.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 GAM21007.1 - 0.015 15.6 0.0 0.036 14.4 0.0 1.6 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SOBP PF15279.6 GAM21007.1 - 0.083 13.5 7.2 0.096 13.3 7.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 GAM21007.1 - 0.091 11.4 6.7 0.084 11.5 6.7 1.1 1 0 0 1 1 1 0 Hamartin protein Bromo_TP PF07524.13 GAM21007.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated FTCD_C PF04961.12 GAM21007.1 - 0.14 11.9 0.4 0.21 11.4 0.4 1.4 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase Med13_C PF06333.12 GAM21007.1 - 1.9 7.7 11.2 2.4 7.3 11.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DnaJ_C PF01556.18 GAM21008.1 - 5.6e-32 110.9 0.2 9.6e-32 110.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAM21008.1 - 2e-22 79.0 0.9 4.3e-22 78.0 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain zf-ribbon_3 PF13248.6 GAM21008.1 - 0.13 11.7 2.8 0.27 10.7 2.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Stc1 PF12898.7 GAM21008.1 - 0.24 12.0 3.3 0.78 10.3 3.3 1.8 1 0 0 1 1 1 0 Stc1 domain Ndc1_Nup PF09531.10 GAM21008.1 - 0.59 8.7 10.4 0.86 8.2 10.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.13 GAM21008.1 - 0.89 9.3 5.8 1.4 8.7 5.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Mtc PF03820.17 GAM21009.1 - 0.095 11.7 1.4 0.11 11.5 1.4 1.1 1 0 0 1 1 1 0 Tricarboxylate carrier DUF2981 PF11200.8 GAM21010.1 - 0.14 11.8 0.4 0.22 11.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) FtsX PF02687.21 GAM21010.1 - 2.4 8.7 7.3 2.8 8.5 3.8 2.6 3 0 0 3 3 3 0 FtsX-like permease family Syndecan PF01034.20 GAM21011.1 - 6.9 6.7 6.8 48 4.0 1.0 3.1 3 0 0 3 3 3 0 Syndecan domain DUF3808 PF10300.9 GAM21012.1 - 4.4e-37 127.9 8.3 2.8e-35 122.0 3.9 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_2 PF07719.17 GAM21012.1 - 2.6e-11 42.7 0.0 0.0075 16.3 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM21012.1 - 4.5e-09 35.7 1.7 0.0031 17.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM21012.1 - 1.7e-08 34.6 3.0 0.47 11.2 0.0 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM21012.1 - 4.4e-08 33.3 0.4 0.27 11.6 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM21012.1 - 4.6e-05 23.6 7.7 0.18 12.0 0.2 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GAM21012.1 - 0.0012 19.5 0.1 2.2 9.3 0.0 4.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM21012.1 - 0.0083 16.3 8.1 0.33 11.3 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.8 GAM21012.1 - 0.028 13.4 0.3 0.42 9.5 0.0 2.7 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 PPR PF01535.20 GAM21012.1 - 0.12 12.7 0.4 22 5.6 0.0 3.9 3 0 0 3 3 3 0 PPR repeat LRR_6 PF13516.6 GAM21013.1 - 3.6e-12 45.3 19.0 0.074 13.1 0.0 8.2 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 GAM21013.1 - 2.1e-05 24.4 0.5 9.4 7.2 0.0 5.4 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 GAM21013.1 - 2.4e-05 24.6 14.5 0.1 13.0 0.1 5.9 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) Carm_PH PF17888.1 GAM21013.1 - 0.00045 20.5 0.5 0.0011 19.2 0.5 1.7 1 0 0 1 1 1 1 Carmil pleckstrin homology domain Myosin_TH1 PF06017.13 GAM21013.1 - 0.077 12.7 2.2 0.11 12.2 0.4 2.0 2 0 0 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding LRR_8 PF13855.6 GAM21013.1 - 0.16 11.8 6.9 14 5.5 0.4 4.7 3 1 0 4 4 4 0 Leucine rich repeat CARMIL_C PF16000.5 GAM21013.1 - 0.82 9.2 24.3 0.29 10.7 13.0 3.2 2 1 0 2 2 2 0 CARMIL C-terminus XRN_N PF03159.18 GAM21014.1 - 4e-40 137.8 0.4 4e-40 137.8 0.4 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 GAM21014.1 - 2.7e-05 23.3 8.6 0.02 13.8 0.1 3.1 3 0 0 3 3 3 2 Xrn1 helical domain XPG_I_2 PF12813.7 GAM21014.1 - 0.1 12.1 0.1 0.28 10.6 0.1 1.7 1 0 0 1 1 1 0 XPG domain containing FG-GAP PF01839.23 GAM21015.1 - 5.6e-28 96.7 28.1 2.7e-11 43.4 1.8 6.2 6 0 0 6 6 6 4 FG-GAP repeat Zn_dep_PLPC PF00882.18 GAM21015.1 - 1.4e-18 67.5 0.2 2.4e-18 66.8 0.2 1.3 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.6 GAM21015.1 - 4.8e-12 46.3 16.3 6.3e-07 29.9 0.9 5.1 3 1 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 GAM21015.1 - 0.0024 18.1 14.7 1.6 9.1 0.4 5.7 6 0 0 6 6 6 2 FG-GAP repeat TcdB_toxin_midN PF12256.8 GAM21015.1 - 0.01 15.2 4.9 3.4 7.0 0.0 4.3 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region PliI PF16743.5 GAM21015.1 - 0.023 14.4 0.3 10 5.9 0.0 3.7 4 0 0 4 4 4 0 Periplasmic lysozyme inhibitor of I-type lysozyme AXE1 PF05448.12 GAM21015.1 - 0.11 11.1 0.1 0.2 10.3 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Pmp3 PF01679.17 GAM21016.1 - 2.9e-21 75.4 13.5 3.7e-21 75.1 13.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator GDI PF00996.18 GAM21017.1 - 7.7e-59 199.3 1.7 2e-43 148.6 0.4 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 GAM21017.1 - 0.035 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Alpha_kinase PF02816.18 GAM21019.1 - 4.7e-54 183.3 1.0 1e-53 182.2 1.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.32 GAM21019.1 - 3.2e-34 116.4 16.5 1.6e-05 25.5 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 GAM21019.1 - 4.9e-10 38.7 16.8 0.0063 15.2 0.1 6.0 2 2 4 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAM21019.1 - 0.00017 21.8 3.1 0.43 10.9 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM21019.1 - 0.0008 18.8 3.5 0.16 11.2 0.2 2.3 1 1 0 2 2 2 2 WD40-like domain Sec3-PIP2_bind PF15277.6 GAM21019.1 - 0.073 13.2 1.8 13 6.0 0.2 3.1 1 1 2 3 3 3 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PALB2_WD40 PF16756.5 GAM21019.1 - 0.21 10.4 5.7 2.1 7.2 1.1 2.7 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain TFIIA PF03153.13 GAM21019.1 - 1.1 9.2 11.2 1.7 8.5 11.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EF_assoc_2 PF08356.12 GAM21020.1 - 3.1e-27 94.4 0.4 2.9e-25 88.1 0.0 2.7 3 0 0 3 3 2 1 EF hand associated Ras PF00071.22 GAM21020.1 - 7e-20 71.2 0.8 2.2e-19 69.7 0.1 2.1 2 0 0 2 2 2 1 Ras family EF_assoc_1 PF08355.12 GAM21020.1 - 6.4e-12 44.9 0.0 1.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 GAM21020.1 - 8.8e-11 42.1 0.0 1.9e-09 37.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GAM21020.1 - 1.8e-08 34.5 0.5 0.071 13.0 0.0 3.5 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM21020.1 - 1.7e-07 31.3 1.0 0.00066 19.7 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.6 GAM21020.1 - 1.8e-07 31.5 0.0 0.016 15.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAM21020.1 - 5.7e-07 28.6 0.1 0.0068 15.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAM21020.1 - 9.1e-07 28.3 0.1 0.01 15.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain Arf PF00025.21 GAM21020.1 - 1.8e-06 27.5 0.8 5.9e-05 22.6 0.2 3.0 2 1 0 2 2 2 1 ADP-ribosylation factor family Septin PF00735.18 GAM21020.1 - 2.2e-05 23.9 0.2 0.019 14.3 0.1 2.6 2 1 0 2 2 2 2 Septin EF-hand_5 PF13202.6 GAM21020.1 - 6.5e-05 22.2 1.9 0.0009 18.6 0.1 2.5 2 0 0 2 2 2 1 EF hand ABC_tran PF00005.27 GAM21020.1 - 7.3e-05 23.3 0.0 0.75 10.3 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA PF00004.29 GAM21020.1 - 0.00012 22.6 0.0 0.8 10.1 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 GAM21020.1 - 0.00048 19.7 1.3 0.029 13.9 0.0 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 GAM21020.1 - 0.0026 17.5 0.1 0.17 11.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAM21020.1 - 0.003 17.1 0.3 0.23 10.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region EF-hand_8 PF13833.6 GAM21020.1 - 0.0038 17.0 0.1 0.14 12.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_28 PF13521.6 GAM21020.1 - 0.0059 16.9 0.0 0.71 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GAM21020.1 - 0.006 16.3 0.1 0.18 11.5 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase SPARC_Ca_bdg PF10591.9 GAM21020.1 - 0.0065 16.8 0.0 1.5 9.2 0.1 3.0 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region RNA_helicase PF00910.22 GAM21020.1 - 0.007 16.7 0.0 6.3 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 GAM21020.1 - 0.0077 16.6 0.0 4.1 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 GAM21020.1 - 0.01 16.4 0.0 0.29 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 GAM21020.1 - 0.02 14.1 0.3 4.2 6.4 0.0 2.7 2 1 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 GAM21020.1 - 0.021 14.0 0.1 1.2 8.2 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 GAM21020.1 - 0.032 14.0 2.6 2.7 7.8 0.4 2.9 3 0 0 3 3 2 0 P-loop containing region of AAA domain MCM PF00493.23 GAM21020.1 - 0.032 13.3 0.1 0.37 9.8 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain FeoB_N PF02421.18 GAM21020.1 - 0.034 13.7 0.9 4.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B NACHT PF05729.12 GAM21020.1 - 0.034 14.1 0.0 2.3 8.1 0.0 2.9 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 GAM21020.1 - 0.041 14.2 3.6 3 8.1 0.1 3.6 3 2 0 3 3 2 0 AAA domain AAA_14 PF13173.6 GAM21020.1 - 0.041 13.9 0.0 6 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAM21020.1 - 0.05 13.7 0.8 3.4 7.7 0.0 2.9 3 0 0 3 3 3 0 Dynamin family AIG1 PF04548.16 GAM21020.1 - 0.052 12.9 0.1 4.8 6.4 0.1 2.4 2 0 0 2 2 2 0 AIG1 family Metalloenzyme PF01676.18 GAM21020.1 - 0.055 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily RuvB_N PF05496.12 GAM21020.1 - 0.086 12.6 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain VirE PF05272.11 GAM21020.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Virulence-associated protein E PduV-EutP PF10662.9 GAM21020.1 - 0.13 12.0 1.1 2 8.2 0.1 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 GAM21020.1 - 0.15 11.6 2.9 17 4.9 0.0 3.4 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 GAM21020.1 - 0.16 11.1 0.0 9.1 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 GAM21020.1 - 0.24 11.1 2.9 3.2 7.5 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 GAM21020.1 - 0.45 10.4 2.9 3.7 7.5 0.1 3.4 4 0 0 4 4 4 0 NTPase Histone PF00125.24 GAM21022.1 - 1.2e-13 51.6 0.4 6.3e-06 26.6 0.5 2.3 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 GAM21022.1 - 3.6e-07 29.8 0.0 7.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 GAM21022.1 - 5.7e-06 26.5 0.0 0.0084 16.4 0.0 2.4 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.27 GAM21023.1 - 2.9e-64 213.0 2.4 6.5e-24 83.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAM21023.1 - 0.0035 16.5 0.7 1.2 8.2 0.1 3.2 2 1 1 3 3 3 2 Gammaproteobacterial serine protease FPL PF09758.9 GAM21024.1 - 9.7e-61 204.1 11.2 2.1e-60 203.0 11.2 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein COMM_domain PF07258.14 GAM21025.1 - 3e-14 52.9 0.3 1.2e-13 51.0 0.0 2.1 3 0 0 3 3 3 1 COMM domain Polyketide_cyc PF03364.20 GAM21026.1 - 1.9e-20 73.4 0.1 2.8e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GAM21026.1 - 1e-07 32.3 0.0 1.8e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport S4 PF01479.25 GAM21027.1 - 1.3e-10 40.8 0.3 4e-10 39.3 0.3 1.9 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 GAM21027.1 - 2.3e-05 25.2 0.4 5.2e-05 24.1 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Nnf1 PF03980.14 GAM21028.1 - 9.1e-17 61.4 1.7 9.1e-17 61.4 1.7 1.4 1 1 0 1 1 1 1 Nnf1 Spc7 PF08317.11 GAM21028.1 - 0.0044 16.0 2.2 0.0046 15.9 2.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ADIP PF11559.8 GAM21028.1 - 0.022 14.8 5.9 0.041 14.0 5.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 GAM21028.1 - 0.13 12.6 1.0 0.4 11.1 0.3 2.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Herpes_BLRF2 PF05812.12 GAM21028.1 - 0.18 11.9 5.5 0.13 12.4 1.7 2.2 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein DivIC PF04977.15 GAM21028.1 - 0.19 11.5 4.2 0.33 10.7 4.2 1.5 1 0 0 1 1 1 0 Septum formation initiator TMF_TATA_bd PF12325.8 GAM21028.1 - 0.2 11.9 7.9 0.041 14.1 4.4 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 GAM21028.1 - 0.27 11.3 9.0 0.3 11.2 9.0 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 GAM21028.1 - 0.3 11.2 5.1 0.81 9.8 4.0 2.1 1 1 1 2 2 2 0 bZIP transcription factor Acetyltransf_11 PF13720.6 GAM21028.1 - 0.52 10.8 2.2 0.52 10.8 0.8 1.8 2 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Abhydrolase_6 PF12697.7 GAM21029.1 - 0.032 14.8 0.3 0.073 13.7 0.3 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DDHD PF02862.17 GAM21030.1 - 0.18 12.0 12.1 4.3 7.4 5.3 3.3 3 0 0 3 3 3 0 DDHD domain TPR_22 PF18833.1 GAM21030.1 - 0.29 11.3 2.3 0.39 10.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat BNIP2 PF12496.8 GAM21030.1 - 0.72 10.3 8.3 1 9.8 0.2 2.6 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PTPA PF03095.15 GAM21031.1 - 3.4e-110 368.2 0.0 3.8e-110 368.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein GAS2 PF02187.17 GAM21032.1 - 1.9e-08 34.3 0.0 7.3e-08 32.4 0.0 2.1 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Snapin_Pallidin PF14712.6 GAM21032.1 - 0.013 15.9 0.1 0.013 15.9 0.1 3.9 4 1 1 5 5 5 0 Snapin/Pallidin bZIP_1 PF00170.21 GAM21032.1 - 0.18 11.9 8.6 2.3 8.4 1.0 3.3 2 0 0 2 2 2 0 bZIP transcription factor HMMR_N PF15905.5 GAM21032.1 - 1.2 8.5 22.1 0.23 10.9 10.7 2.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 GAM21032.1 - 1.4 8.2 20.9 0.072 12.4 13.1 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 GAM21032.1 - 2.4 8.5 8.5 1.2 9.4 0.3 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper M PF02370.16 GAM21032.1 - 3.6 8.5 8.7 2.1 9.2 2.6 3.0 2 0 0 2 2 2 0 M protein repeat UPF0242 PF06785.11 GAM21032.1 - 4.7 7.3 25.5 0.28 11.3 11.2 2.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 GAM21032.1 - 8.2 6.5 16.1 0.66 10.0 8.9 3.0 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF724 PF05266.14 GAM21032.1 - 8.9 6.1 16.5 3 7.6 9.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) eIF-4B PF06273.11 GAM21032.1 - 9.5 5.1 9.6 7 5.6 1.7 2.4 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B Herpes_LMP1 PF05297.11 GAM21033.1 - 0.2 10.8 5.1 0.24 10.6 5.1 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) TPD PF14811.6 GAM21034.1 - 1.7e-45 154.3 0.1 2.9e-45 153.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif HTH_38 PF13936.6 GAM21034.1 - 0.056 13.2 0.0 4.2 7.2 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain SF3b10 PF07189.11 GAM21035.1 - 6.6e-35 119.1 0.0 7.5e-35 118.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Glyco_hydro_9 PF00759.19 GAM21036.1 - 1.5e-122 410.0 8.9 1.5e-122 410.0 8.9 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 CBM49 PF09478.10 GAM21036.1 - 2.2e-18 66.3 0.5 2.2e-18 66.3 0.5 1.8 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 Dicty_spore_N PF04562.12 GAM21038.1 - 1.4e-17 64.4 24.5 1.4e-17 64.4 24.5 7.7 2 1 5 8 8 8 1 Dictyostelium spore coat protein, N terminus CBM49 PF09478.10 GAM21038.1 - 0.00019 21.7 0.0 0.00035 20.8 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Dynamin_N PF00350.23 GAM21039.1 - 1.2e-09 38.4 0.0 2.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family U62_UL91 PF17442.2 GAM21039.1 - 0.0025 17.8 0.6 1.1 9.3 0.1 3.5 3 0 0 3 3 3 1 Functional domain of U62 and UL91 proteins AAA_15 PF13175.6 GAM21039.1 - 0.0068 16.2 1.0 0.034 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain C9orf72-like PF15019.6 GAM21039.1 - 0.0087 15.6 0.0 0.026 14.1 0.0 1.8 1 0 0 1 1 1 1 C9orf72-like protein family ABC_tran PF00005.27 GAM21039.1 - 0.16 12.5 0.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 GAM21039.1 - 0.9 9.9 4.1 6.5 7.1 0.0 3.7 3 1 0 3 3 3 0 AAA ATPase domain Hemocyanin_M PF00372.19 GAM21040.1 - 9.5e-38 129.9 0.0 1.6e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Hemocyanin_C PF03723.14 GAM21040.1 - 1.6e-33 116.1 0.1 2.4e-33 115.5 0.1 1.4 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Tyrosinase PF00264.20 GAM21040.1 - 0.00021 21.6 0.2 0.00064 20.1 0.1 1.9 2 0 0 2 2 2 1 Common central domain of tyrosinase DnaJ PF00226.31 GAM21041.1 - 6.9e-15 54.9 0.3 1.7e-14 53.7 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.31 GAM21042.1 - 8.5e-14 51.4 0.2 2.5e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain Vps52 PF04129.12 GAM21043.1 - 9.9e-89 298.4 19.4 1.9e-88 297.4 19.4 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Pur_ac_phosph_N PF16656.5 GAM21044.1 - 5.1e-20 71.9 1.4 5.1e-20 71.9 1.4 2.4 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 GAM21044.1 - 1.4e-18 68.2 0.6 2.3e-18 67.4 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 GAM21044.1 - 1.6e-15 57.7 0.3 7.1e-15 55.6 0.3 2.2 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 GAM21044.1 - 0.018 15.2 0.0 0.047 13.9 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.10 GAM21044.1 - 0.059 12.4 0.0 0.89 8.5 0.0 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase Rhomboid PF01694.22 GAM21045.1 - 1.1e-32 113.1 9.9 1.1e-32 113.1 9.9 1.8 2 0 0 2 2 2 1 Rhomboid family DUF1129 PF06570.11 GAM21045.1 - 0.02 14.4 5.8 5 6.5 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Phage_holin_3_3 PF16083.5 GAM21045.1 - 0.054 13.6 5.8 0.046 13.8 3.4 2.1 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III dUTPase PF00692.19 GAM21046.1 - 5.9e-12 45.4 0.0 1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 dUTPase LAGLIDADG_3 PF14528.6 GAM21046.1 - 0.0026 18.0 0.0 0.0062 16.8 0.0 1.6 1 0 0 1 1 1 1 LAGLIDADG-like domain DnaJ PF00226.31 GAM21047.1 - 7.9e-23 80.4 2.9 1.4e-22 79.5 2.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 GAM21047.1 - 2.6e-19 69.8 0.0 3.6e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 GAM21047.1 - 8.3e-08 32.5 11.7 5.1e-07 30.0 12.1 2.2 1 1 0 1 1 1 1 DnaJ central domain Abi_HHR PF07815.14 GAM21047.1 - 0.0069 16.5 0.6 0.086 13.0 0.3 2.4 2 0 0 2 2 2 1 Abl-interactor HHR CxC3 PF18804.1 GAM21047.1 - 0.029 14.2 5.4 0.049 13.5 5.4 1.4 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Anti-TRAP PF15777.5 GAM21047.1 - 0.055 13.4 11.0 0.048 13.6 2.0 2.8 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Trypan_PARP PF05887.11 GAM21047.1 - 0.06 13.3 1.0 0.12 12.4 1.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3603 PF12227.8 GAM21047.1 - 0.1 11.9 0.3 0.18 11.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Lar_restr_allev PF14354.6 GAM21047.1 - 6.5 7.2 6.9 25 5.4 0.0 3.1 2 1 1 3 3 3 0 Restriction alleviation protein Lar HypA PF01155.19 GAM21047.1 - 7.1 6.7 8.6 2.2e+02 1.9 9.6 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ECH_1 PF00378.20 GAM21048.1 - 2.2e-37 128.7 0.0 2.5e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM21048.1 - 1e-17 64.6 0.0 2.4e-17 63.5 0.0 1.5 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase AAA_28 PF13521.6 GAM21049.1 - 0.00085 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAM21049.1 - 0.0081 16.3 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM21049.1 - 0.011 16.3 0.0 0.031 14.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAM21049.1 - 0.024 14.6 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM21049.1 - 0.026 14.9 0.0 0.093 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 GAM21049.1 - 0.057 13.7 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAM21049.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 GAM21049.1 - 0.071 12.8 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 GAM21049.1 - 0.081 12.2 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Cg6151-P PF10233.9 GAM21050.1 - 0.033 14.5 13.3 0.094 13.0 13.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF2070 PF09843.9 GAM21050.1 - 0.051 11.9 3.4 0.062 11.6 3.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SdrD_B PF17210.3 GAM21051.1 - 1.8e-95 314.8 138.4 2.6e-10 40.5 1.4 23.1 23 0 0 23 23 22 20 SdrD B-like domain SpaA PF17802.1 GAM21051.1 - 2e-06 28.0 88.7 0.006 16.9 0.1 18.3 19 2 1 20 20 19 5 Prealbumin-like fold domain bMG6 PF17962.1 GAM21051.1 - 1.7e-05 24.9 0.8 1.4 9.1 0.0 6.1 7 0 0 7 7 6 1 Bacterial macroglobulin domain 6 bMG3 PF11974.8 GAM21051.1 - 0.00012 22.0 2.8 3.4 7.7 0.0 6.7 7 0 0 7 7 7 1 Bacterial alpha-2-macroglobulin MG3 domain DUF4723 PF15851.5 GAM21051.1 - 0.0026 17.9 7.6 11 6.2 0.0 6.8 7 0 0 7 7 7 1 Domain of unknown function (DUF4723) DUF2012 PF09430.10 GAM21051.1 - 0.0026 17.9 0.0 32 4.6 0.0 5.7 8 0 0 8 8 7 0 Protein of unknown function (DUF2012) DUF1533 PF07550.11 GAM21051.1 - 0.0027 17.6 4.2 3.4 7.6 0.1 5.9 7 0 0 7 7 7 1 Protein of unknown function (DUF1533) DIX PF00778.17 GAM21051.1 - 0.0052 16.6 0.2 36 4.3 0.0 5.0 5 0 0 5 5 5 0 DIX domain DUF3244 PF11589.8 GAM21051.1 - 0.031 14.3 14.1 6 7.0 0.0 7.9 10 0 0 10 10 9 0 Domain of unknown function (DUF3244) DUF1416 PF07210.12 GAM21051.1 - 0.035 14.0 0.1 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) CarboxypepD_reg PF13620.6 GAM21051.1 - 0.076 13.3 0.1 0.076 13.3 0.1 16.8 21 3 1 22 22 21 0 Carboxypeptidase regulatory-like domain FOLN PF09289.10 GAM21051.1 - 4.9 7.4 10.1 0.41 10.9 3.1 3.2 3 0 0 3 3 3 0 Follistatin/Osteonectin-like EGF domain DUF3659 PF12396.8 GAM21051.1 - 6.1 6.8 11.5 10 6.1 0.2 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3659) Ephrin_rec_like PF07699.13 GAM21052.1 - 2.7e-09 36.7 36.6 1e-05 25.2 5.8 7.3 3 1 5 8 8 8 6 Putative ephrin-receptor like Vpu PF00558.19 GAM21052.1 - 0.01 15.6 0.2 0.02 14.6 0.2 1.4 1 0 0 1 1 1 0 Vpu protein Macoilin PF09726.9 GAM21052.1 - 0.061 11.9 6.1 0.072 11.6 6.1 1.1 1 0 0 1 1 1 0 Macoilin family Emaravirus_P4 PF16505.5 GAM21052.1 - 0.063 12.3 0.2 0.095 11.7 0.2 1.1 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily Chi-conotoxin PF16981.5 GAM21052.1 - 0.084 13.1 1.7 0.19 12.0 0.5 2.4 1 1 0 1 1 1 0 chi-Conotoxin or t superfamily Apt1 PF10351.9 GAM21052.1 - 0.2 10.5 3.9 0.25 10.2 3.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC24 PF15669.5 GAM21052.1 - 0.3 10.9 3.4 0.55 10.1 3.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family VSP PF03302.13 GAM21052.1 - 1.1 8.0 50.2 0.036 12.9 23.7 3.1 2 1 2 4 4 4 0 Giardia variant-specific surface protein SIT PF15330.6 GAM21052.1 - 1.7 9.1 4.2 7.1 7.1 0.0 2.7 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF1635 PF07795.11 GAM21052.1 - 2.4 8.0 8.7 4 7.2 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Pex14_N PF04695.13 GAM21052.1 - 3.2 8.4 8.6 2.6 8.7 5.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 GAM21052.1 - 3.4 7.2 22.5 8.2 6.0 22.5 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Miga PF10265.9 GAM21052.1 - 7 5.5 6.5 56 2.5 0.0 2.0 2 0 0 2 2 2 0 Mitoguardin TraP PF07296.11 GAM21053.1 - 0.1 11.8 0.1 0.1 11.8 0.1 2.1 2 0 0 2 2 2 0 TraP protein Orf78 PF06024.12 GAM21053.1 - 0.54 10.6 2.4 42 4.5 0.3 3.1 2 0 0 2 2 2 0 Orf78 (ac78) Glyco_hydro_18 PF00704.28 GAM21054.1 - 2.9e-21 76.5 0.0 3.8e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-SNAP50_C PF12251.8 GAM21055.1 - 1.1e-64 217.8 5.8 1.6e-64 217.3 5.8 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal UBA2_C PF16195.5 GAM21055.1 - 0.043 14.5 1.9 0.079 13.7 1.9 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Adeno_E1A PF02703.14 GAM21055.1 - 0.085 12.4 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Early E1A protein PI-PLC-X PF00388.19 GAM21056.1 - 1.1e-58 197.0 0.1 2e-58 196.1 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAM21056.1 - 4.2e-33 114.1 1.4 1.3e-32 112.5 0.0 2.6 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 GAM21056.1 - 7.4e-15 55.1 0.0 2.2e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 GAM21056.1 - 3.1e-06 27.6 0.1 1e-05 25.9 0.1 2.0 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_12 PF16457.5 GAM21056.1 - 0.13 12.8 1.0 0.82 10.2 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain EF-hand_7 PF13499.6 GAM21056.1 - 0.59 10.6 3.1 2.9 8.4 1.8 2.4 2 0 0 2 2 2 0 EF-hand domain pair EGF_2 PF07974.13 GAM21057.1 - 0.48 10.8 6.0 1.2 9.6 6.0 1.7 1 0 0 1 1 1 0 EGF-like domain DUF3730 PF12530.8 GAM21058.1 - 9.9e-47 159.4 0.7 9.9e-47 159.4 0.7 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3730) HEAT_2 PF13646.6 GAM21058.1 - 7.2e-06 26.3 8.1 0.11 12.9 0.1 6.8 5 2 0 6 6 6 2 HEAT repeats FliG_M PF14841.6 GAM21058.1 - 0.02 15.1 0.6 5.7 7.2 0.0 4.0 3 0 0 3 3 3 0 FliG middle domain HEAT_EZ PF13513.6 GAM21058.1 - 0.023 15.2 5.6 27 5.4 0.2 5.6 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 GAM21058.1 - 0.087 13.1 16.2 9.4 6.8 0.1 8.8 9 0 0 9 9 9 0 HEAT repeat Ricin_B_lectin PF00652.22 GAM21059.1 - 0.00011 22.5 2.1 0.001 19.3 0.3 2.6 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain ABC_membrane PF00664.23 GAM21060.1 - 2.1e-50 171.9 25.0 1.8e-31 109.8 11.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM21060.1 - 7.6e-50 169.0 0.0 1.7e-27 96.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM21060.1 - 8.4e-10 38.5 0.7 0.0014 18.1 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAM21060.1 - 4.9e-05 23.4 0.6 0.25 11.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 GAM21060.1 - 0.00012 22.6 1.9 0.085 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAM21060.1 - 0.00022 21.2 0.3 0.015 15.2 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 GAM21060.1 - 0.0012 18.5 4.3 0.38 10.5 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 GAM21060.1 - 0.0013 18.6 0.2 7.6 6.2 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 GAM21060.1 - 0.043 12.8 0.5 2.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 GAM21060.1 - 0.056 13.5 0.9 3.1 7.8 0.3 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 GAM21060.1 - 0.067 13.5 0.3 9.8 6.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.9 GAM21060.1 - 0.085 11.6 0.6 4.2 6.0 0.0 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AIG1 PF04548.16 GAM21060.1 - 2.8 7.2 6.3 3.1 7.1 0.2 2.7 3 0 0 3 3 3 0 AIG1 family Dynamin_N PF00350.23 GAM21060.1 - 5.1 7.1 5.8 1.5 8.8 0.6 2.3 2 0 0 2 2 2 0 Dynamin family Pterin_bind PF00809.22 GAM21061.1 - 2.7e-69 233.5 0.0 4e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 GAM21061.1 - 1.7e-35 121.9 0.0 2.8e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 GAM21061.1 - 4.7e-15 56.1 0.0 1e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 Dihydroneopterin aldolase RhoGEF PF00621.20 GAM21062.1 - 5.5e-37 127.8 0.2 5.5e-37 127.8 0.2 2.9 3 1 0 3 3 3 1 RhoGEF domain Arm PF00514.23 GAM21062.1 - 3.6e-13 49.1 12.4 9.8e-05 22.3 0.2 7.5 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat PH PF00169.29 GAM21062.1 - 2.4e-09 37.6 0.9 6.2e-09 36.3 0.9 1.7 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 GAM21062.1 - 4.5e-06 26.7 2.8 1.8e-05 24.7 1.4 2.3 2 0 0 2 2 2 1 PH domain Arm_2 PF04826.13 GAM21062.1 - 0.00077 19.0 13.1 0.0093 15.5 8.2 2.9 2 0 0 2 2 2 1 Armadillo-like NopRA1 PF16201.5 GAM21062.1 - 0.011 15.4 4.2 0.12 11.9 0.5 3.2 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 DUF913 PF06025.12 GAM21062.1 - 0.012 14.6 0.3 0.039 12.9 0.3 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RICTOR_V PF14668.6 GAM21062.1 - 0.026 14.8 0.7 8 6.8 0.1 3.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 PH_13 PF16652.5 GAM21062.1 - 0.033 14.0 5.8 3.1 7.6 5.8 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain CTNNBL PF08216.11 GAM21062.1 - 0.072 13.3 5.4 1.2 9.3 0.2 4.0 2 1 1 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear V-ATPase_H_C PF11698.8 GAM21062.1 - 0.15 12.2 1.8 0.45 10.6 0.5 2.6 2 1 0 2 2 2 0 V-ATPase subunit H Flagellar_put PF12611.8 GAM21062.1 - 0.18 11.6 1.5 0.51 10.2 1.5 1.7 1 0 0 1 1 1 0 Putative flagellar HEAT_EZ PF13513.6 GAM21062.1 - 0.18 12.4 1.8 18 6.0 0.0 4.4 6 1 1 7 7 7 0 HEAT-like repeat DUF3361 PF11841.8 GAM21062.1 - 3.8 7.4 17.5 1.4 8.8 0.7 4.3 2 1 3 5 5 5 0 Domain of unknown function (DUF3361) ADH_N PF08240.12 GAM21063.1 - 4.2e-29 100.6 6.4 8.2e-29 99.7 6.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM21063.1 - 6.8e-16 58.4 0.0 1.2e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM21063.1 - 0.00014 22.9 0.0 0.00028 21.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAM21063.1 - 0.0072 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAM21063.1 - 0.0092 15.3 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 GAM21063.1 - 0.023 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Oxidored_nitro PF00148.19 GAM21063.1 - 0.034 12.9 0.0 0.048 12.4 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase CoA_binding PF02629.19 GAM21063.1 - 0.11 13.2 0.3 0.76 10.5 0.1 2.3 2 0 0 2 2 2 0 CoA binding domain Cortex-I_coil PF09304.10 GAM21064.1 - 9.8e-46 154.4 26.4 1.1e-45 154.2 21.1 2.7 2 0 0 2 2 2 1 Cortexillin I, coiled coil CH PF00307.31 GAM21064.1 - 7.1e-40 135.6 0.0 6.1e-19 68.2 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM21064.1 - 0.0041 16.9 0.0 3.7 7.4 0.0 2.7 2 1 0 2 2 2 2 CAMSAP CH domain DUF4407 PF14362.6 GAM21064.1 - 0.19 11.0 8.3 0.33 10.3 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4239 PF14023.6 GAM21064.1 - 0.58 9.8 1.7 0.94 9.2 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Baculo_PEP_C PF04513.12 GAM21064.1 - 2.3 8.2 7.4 1.6 8.8 2.9 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 GAM21064.1 - 4.3 7.4 9.5 0.27 11.3 2.8 2.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) ZapB PF06005.12 GAM21064.1 - 7.6 7.1 31.5 0.47 10.9 2.5 3.0 3 0 0 3 3 3 0 Cell division protein ZapB F420_oxidored PF03807.17 GAM21065.1 - 2.4e-07 31.2 0.3 4.5e-07 30.4 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAM21065.1 - 0.0033 17.6 0.4 0.014 15.5 0.1 1.9 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 GAM21065.1 - 0.0059 16.5 0.7 0.019 14.9 0.2 1.8 2 0 0 2 2 2 1 Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 GAM21065.1 - 0.018 15.1 0.2 0.56 10.2 0.1 2.4 1 1 1 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus I_LWEQ PF01608.17 GAM21066.1 - 8.5e-47 159.2 36.3 4.9e-45 153.5 8.9 4.4 3 1 1 4 4 4 3 I/LWEQ domain ANTH PF07651.16 GAM21066.1 - 1.8e-43 148.5 0.4 1.8e-43 148.5 0.4 3.0 3 1 0 3 3 3 1 ANTH domain ENTH PF01417.20 GAM21066.1 - 8.1e-07 29.1 0.1 3.6e-06 27.0 0.1 2.2 1 0 0 1 1 1 1 ENTH domain FAM184 PF15665.5 GAM21066.1 - 0.0016 18.2 10.8 0.0016 18.2 10.8 2.6 3 1 0 3 3 3 1 Family with sequence similarity 184, A and B HAP1_N PF04849.13 GAM21066.1 - 0.016 14.4 13.6 0.047 12.9 13.6 1.7 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Pox_A_type_inc PF04508.12 GAM21066.1 - 0.041 13.8 3.8 0.034 14.0 1.1 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2969 PF11184.8 GAM21066.1 - 0.069 13.6 1.4 0.22 11.9 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) Spc29 PF17082.5 GAM21066.1 - 0.27 11.0 8.7 0.015 15.1 2.7 1.9 2 0 0 2 2 2 0 Spindle Pole Component 29 Jnk-SapK_ap_N PF09744.9 GAM21066.1 - 1.5 9.1 19.4 0.89 9.8 10.1 3.6 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF4298 PF14131.6 GAM21066.1 - 1.9 8.5 9.2 2.7 8.0 2.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) PX PF00787.24 GAM21067.1 - 4.3e-15 55.7 1.3 7.6e-15 54.9 0.4 1.8 2 0 0 2 2 2 1 PX domain C2 PF00168.30 GAM21067.1 - 0.0029 17.8 0.9 0.012 15.9 0.1 2.5 2 1 1 3 3 3 1 C2 domain LIM PF00412.22 GAM21068.1 - 8e-28 96.5 33.8 2.4e-11 43.7 2.2 4.1 3 1 0 4 4 4 3 LIM domain DUF678 PF05077.12 GAM21068.1 - 1 9.5 0.0 1 9.5 0.0 4.3 4 2 1 5 5 5 0 Protein of unknown function (DUF678) RIX1 PF08167.12 GAM21069.1 - 1.6e-12 47.6 6.2 1.6e-12 47.6 6.2 3.1 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis BSP_II PF05432.11 GAM21069.1 - 7.9 6.1 36.4 0.11 12.2 26.1 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) F_actin_bund_C PF18060.1 GAM21070.1 - 7.3e-20 70.9 1.9 1.4e-19 70.0 1.9 1.4 1 0 0 1 1 1 1 F actin bundling C terminal EF-hand_5 PF13202.6 GAM21070.1 - 0.024 14.1 0.0 0.075 12.6 0.0 1.8 1 0 0 1 1 1 0 EF hand Sec23_helical PF04815.15 GAM21070.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Sec23/Sec24 helical domain EF-hand_13 PF17958.1 GAM21071.1 - 8.1e-25 86.5 0.4 1.2e-21 76.3 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 GAM21071.1 - 4.2e-17 62.4 1.6 4.2e-17 62.4 1.6 3.5 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM21071.1 - 0.0035 17.1 0.5 0.42 10.7 0.1 3.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 GAM21071.1 - 0.011 15.6 0.8 0.084 12.7 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 GAM21071.1 - 0.015 14.8 2.8 0.25 11.0 0.2 3.4 3 0 0 3 3 3 0 EF hand DUF2572 PF10833.8 GAM21071.1 - 0.037 13.8 5.0 0.074 12.8 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Med3 PF11593.8 GAM21071.1 - 2.4 7.3 17.7 4.2 6.5 17.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SPARC_Ca_bdg PF10591.9 GAM21071.1 - 9 6.7 13.9 2.9 8.2 0.2 3.8 4 0 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Exo_endo_phos PF03372.23 GAM21072.1 - 5.1e-24 85.1 0.0 4e-23 82.1 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAM21072.1 - 0.6 10.0 2.3 1.1 9.1 0.3 2.6 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Tub_N PF16322.5 GAM21072.1 - 0.73 10.2 11.6 1.1 9.6 11.6 1.2 1 0 0 1 1 1 0 Tubby N-terminal Choline_kinase PF01633.20 GAM21073.1 - 4.6e-59 199.6 0.2 4.6e-59 199.6 0.2 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 GAM21073.1 - 3.5e-07 30.4 0.0 4.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAM21073.1 - 0.00062 19.2 2.6 0.0036 16.7 0.6 2.1 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 GAM21073.1 - 0.00089 18.2 1.4 0.0015 17.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Tim17 PF02466.19 GAM21074.1 - 4.9e-05 23.7 3.0 8.2e-05 22.9 3.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3087 PF11286.8 GAM21074.1 - 0.0049 16.3 0.1 0.01 15.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3087) DUF2104 PF09877.9 GAM21074.1 - 0.1 12.9 0.2 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) NUDIX_2 PF13869.6 GAM21075.1 - 1.6e-78 262.7 0.0 1.7e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.28 GAM21075.1 - 0.0067 16.5 0.0 0.0092 16.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Snf7 PF03357.21 GAM21077.1 - 8.4e-31 106.9 20.1 1e-30 106.6 20.1 1.1 1 0 0 1 1 1 1 Snf7 DUF4365 PF14280.6 GAM21077.1 - 0.0093 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4365) pRN1_helical PF13010.6 GAM21077.1 - 2.1 8.3 6.7 2 8.4 5.7 1.6 1 1 0 1 1 1 0 Primase helical domain tRNA_int_end_N2 PF12928.7 GAM21078.1 - 4e-12 46.1 0.9 5.3e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 GAM21078.1 - 0.00036 20.1 0.1 0.00064 19.3 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain HABP4_PAI-RBP1 PF04774.15 GAM21078.1 - 0.19 12.6 6.3 0.38 11.6 6.3 1.5 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family DHR-2 PF06920.13 GAM21079.1 - 1e-99 334.6 4.4 1.6e-99 334.0 4.4 1.4 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 GAM21079.1 - 4.1e-30 105.1 0.5 4.1e-30 105.1 0.5 2.2 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 GAM21079.1 - 4.3e-14 52.2 0.1 4.3e-14 52.2 0.1 2.4 3 0 0 3 3 3 1 DOCK N-terminus SH3_2 PF07653.17 GAM21079.1 - 5.9e-05 22.7 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Myotub-related PF06602.14 GAM21082.1 - 3.5e-07 29.5 8.3 1.7e-05 23.9 0.0 3.7 4 0 0 4 4 4 2 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 GAM21082.1 - 2.8e-05 24.2 0.0 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family WH1 PF00568.23 GAM21083.1 - 6.4e-20 71.2 0.2 8.9e-20 70.7 0.2 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 GAM21083.1 - 3.3e-17 62.6 0.1 7.2e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 GAM21083.1 - 2.6e-08 33.4 0.2 7.5e-08 32.0 0.2 1.8 1 0 0 1 1 1 1 WH2 motif DCP1 PF06058.13 GAM21083.1 - 0.0013 18.7 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family DDRGK PF09756.9 GAM21085.1 - 6.6e-60 201.9 35.8 6.6e-60 201.9 35.8 2.1 2 0 0 2 2 2 2 DDRGK domain B-block_TFIIIC PF04182.12 GAM21085.1 - 0.028 14.6 0.0 0.085 13.0 0.0 1.8 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC RecQ_Zn_bind PF16124.5 GAM21085.1 - 0.11 13.2 0.4 0.11 13.2 0.4 3.5 3 1 0 3 3 3 0 RecQ zinc-binding Tox-ART-HYE1 PF15634.6 GAM21086.1 - 1.1e-05 25.0 2.0 2.5e-05 23.8 2.0 1.6 1 0 0 1 1 1 1 HYE1 signature containing ADP-ribosyltransferase AAA PF00004.29 GAM21087.1 - 5.8e-43 146.5 0.0 1.2e-42 145.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM21087.1 - 9.5e-09 34.9 2.2 9.6e-09 34.9 0.7 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 GAM21087.1 - 1.3e-07 32.1 0.1 0.00017 22.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 GAM21087.1 - 2.1e-07 31.0 0.1 3.8e-06 27.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAM21087.1 - 2.4e-06 27.4 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAM21087.1 - 1.9e-05 24.8 0.0 4.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAM21087.1 - 5.6e-05 23.4 0.4 0.0058 16.9 0.0 2.7 2 1 1 3 3 3 1 AAA domain Prot_ATP_ID_OB PF16450.5 GAM21087.1 - 0.00021 21.2 0.0 0.00049 20.0 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_7 PF12775.7 GAM21087.1 - 0.0011 18.5 0.0 0.0025 17.3 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 GAM21087.1 - 0.0014 19.0 0.0 0.0053 17.1 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.6 GAM21087.1 - 0.0014 19.2 0.0 0.004 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAM21087.1 - 0.0017 18.1 0.1 0.0074 16.0 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 GAM21087.1 - 0.0019 17.4 0.0 0.0034 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 GAM21087.1 - 0.002 17.4 0.1 0.0057 15.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 GAM21087.1 - 0.0036 17.3 0.0 0.0087 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAM21087.1 - 0.0037 16.7 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 GAM21087.1 - 0.0037 17.2 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAM21087.1 - 0.0055 16.9 0.0 0.0094 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAM21087.1 - 0.007 16.1 0.0 0.023 14.4 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 GAM21087.1 - 0.008 16.0 0.0 0.026 14.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 GAM21087.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 GAM21087.1 - 0.019 14.9 0.2 0.071 13.0 0.0 2.1 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 GAM21087.1 - 0.027 14.4 0.0 0.061 13.2 0.0 1.6 2 0 0 2 2 1 0 NACHT domain AAA_24 PF13479.6 GAM21087.1 - 0.038 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAM21087.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GAM21087.1 - 0.055 12.8 0.0 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 GAM21087.1 - 0.056 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 GAM21087.1 - 0.078 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 GAM21087.1 - 0.081 12.9 0.0 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GAM21087.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain YkuI_C PF10388.9 GAM21087.1 - 0.12 12.1 0.8 0.29 10.9 0.8 1.6 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain AAA_11 PF13086.6 GAM21087.1 - 0.14 12.0 1.8 0.35 10.6 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 GAM21087.1 - 0.17 11.4 0.3 0.43 10.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF1043 PF06295.12 GAM21087.1 - 0.52 10.3 3.1 0.99 9.4 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FeS_assembly_P PF01883.19 GAM21088.1 - 1e-13 51.2 0.0 1.7e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein FUSC PF04632.12 GAM21090.1 - 0.59 8.6 8.7 0.86 8.1 8.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mce4_CUP1 PF11887.8 GAM21090.1 - 0.99 8.8 13.2 0.059 12.8 3.2 2.2 1 1 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Baculo_PEP_N PF04512.12 GAM21090.1 - 2.4 8.5 6.6 4.8 7.5 0.9 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus LRR_8 PF13855.6 GAM21091.1 - 1.2e-42 143.4 52.6 1.3e-09 37.7 1.7 8.1 4 2 2 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 GAM21091.1 - 1.2e-38 130.5 63.0 1.7e-08 34.6 4.5 9.6 4 3 7 12 12 12 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM21091.1 - 4.7e-14 50.8 39.4 0.47 11.2 0.1 14.2 15 1 0 15 15 15 5 Leucine Rich Repeat YdiH PF15930.5 GAM21091.1 - 0.044 14.0 0.7 16 5.7 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function Novirhabdo_Nv PF05554.11 GAM21091.1 - 0.14 12.0 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein LRR_6 PF13516.6 GAM21091.1 - 0.18 12.0 0.3 0.18 12.0 0.3 12.9 14 0 0 14 14 14 0 Leucine Rich repeat LRR_5 PF13306.6 GAM21091.1 - 0.6 10.1 3.5 2.2 8.2 0.7 2.9 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) SnoaL_2 PF12680.7 GAM21093.1 - 0.017 15.8 0.0 0.02 15.5 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain PPP4R2 PF09184.11 GAM21094.1 - 0.24 10.9 8.9 0.24 11.0 8.9 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 GAM21094.1 - 0.25 10.6 14.1 0.22 10.8 14.1 1.0 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 GAM21094.1 - 0.42 10.3 10.9 0.42 10.3 10.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 GAM21094.1 - 0.5 10.4 6.5 0.5 10.4 6.5 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 GAM21094.1 - 1.2 7.4 7.1 1.1 7.5 7.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAM21094.1 - 1.5 6.8 14.4 1.3 7.0 14.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 GAM21094.1 - 1.5 6.8 10.0 1.8 6.6 10.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.9 GAM21094.1 - 2.3 7.2 16.6 2.1 7.4 16.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 GAM21094.1 - 2.5 6.2 10.0 2.2 6.4 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 GAM21094.1 - 2.7 7.8 13.1 2.8 7.8 13.1 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region GCIP PF13324.6 GAM21094.1 - 4.8 6.7 12.0 5 6.6 12.0 1.0 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting bZIP_2 PF07716.15 GAM21095.1 - 5.1e-08 32.9 5.1 5.1e-08 32.9 5.1 3.8 4 0 0 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.21 GAM21095.1 - 2.4e-06 27.6 3.8 2.4e-06 27.6 3.8 2.5 3 0 0 3 3 3 1 bZIP transcription factor CBM49 PF09478.10 GAM21097.1 - 8.3e-11 42.0 0.1 1.8e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF2393 PF09624.10 GAM21097.1 - 0.064 13.3 0.1 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) DUF3439 PF11921.8 GAM21097.1 - 6.6 6.7 11.7 6.7 6.7 10.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PARP PF00644.20 GAM21098.1 - 1.7e-64 217.0 0.0 1.7e-64 217.0 0.0 3.3 3 1 1 4 4 4 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 GAM21098.1 - 5e-46 156.2 1.8 6.9e-46 155.7 0.7 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 GAM21098.1 - 6.3e-25 87.0 2.6 2e-24 85.4 2.6 1.9 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 GAM21098.1 - 1.2e-10 41.7 0.1 2e-09 37.7 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM21098.1 - 1.8e-07 31.4 0.1 7.6e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 GAM21098.1 - 0.004 17.1 0.1 0.0081 16.1 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_3 PF18428.1 GAM21098.1 - 0.0092 16.0 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Vps51 PF08700.11 GAM21101.1 - 0.02 15.0 0.2 0.02 15.0 0.2 3.7 4 0 0 4 4 4 0 Vps51/Vps67 Preseq_ALAS PF09029.10 GAM21101.1 - 0.043 14.3 1.3 0.076 13.5 0.3 1.9 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence Aminotran_1_2 PF00155.21 GAM21101.1 - 0.32 10.1 3.2 0.67 9.1 0.1 2.2 2 0 0 2 2 2 0 Aminotransferase class I and II UPF0149 PF03695.13 GAM21101.1 - 1.1 9.5 4.8 3.1 8.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) Vpu PF00558.19 GAM21101.1 - 1.9 8.3 5.5 1.3 8.8 2.4 2.5 2 0 0 2 2 2 0 Vpu protein NAD_binding_6 PF08030.12 GAM21101.1 - 7.9 6.6 9.7 96 3.1 9.7 2.3 1 1 0 1 1 1 0 Ferric reductase NAD binding domain DUF4834 PF16118.5 GAM21101.1 - 9.3 7.3 9.2 0.28 12.2 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) COMM_domain PF07258.14 GAM21102.1 - 7.6e-13 48.4 6.9 7.6e-13 48.4 6.9 1.8 2 0 0 2 2 2 1 COMM domain DUF4061 PF13270.6 GAM21102.1 - 2.6 8.4 8.4 0.58 10.5 2.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) RRM_1 PF00076.22 GAM21103.1 - 4.3e-13 48.9 4.1 5.7e-11 42.1 0.1 3.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM21103.1 - 0.00035 20.1 0.1 0.038 13.6 0.0 3.1 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COG2 PF06148.11 GAM21103.1 - 0.019 15.0 8.4 0.035 14.2 0.9 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SpoIIID PF12116.8 GAM21103.1 - 0.12 12.5 1.4 0.39 10.8 0.1 2.6 2 1 0 2 2 2 0 Stage III sporulation protein D COG5 PF10392.9 GAM21103.1 - 0.18 11.9 9.0 4.6 7.4 2.0 3.1 2 1 0 3 3 3 0 Golgi transport complex subunit 5 XhlA PF10779.9 GAM21103.1 - 1.7 8.9 5.0 2.4 8.4 1.3 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Occludin_ELL PF07303.13 GAM21103.1 - 2.3 9.0 8.4 0.44 11.3 0.1 3.4 3 0 0 3 3 3 0 Occludin homology domain DUF5082 PF16888.5 GAM21103.1 - 4 7.7 17.4 18 5.7 2.4 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 GAM21103.1 - 9.9 6.2 15.6 0.61 10.1 1.7 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 GAM21104.1 - 1.6e-70 237.5 0.0 2.7e-70 236.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21104.1 - 1.3e-50 172.2 0.0 2e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM21104.1 - 2.4e-07 29.9 0.0 2.4e-07 29.9 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 GAM21104.1 - 0.017 15.3 0.3 0.1 12.8 0.0 2.2 2 0 0 2 2 2 0 ABC1 family Kinase-like PF14531.6 GAM21104.1 - 0.017 14.4 0.0 0.058 12.7 0.0 1.8 1 1 0 1 1 1 0 Kinase-like RecT PF03837.14 GAM21104.1 - 5.4 6.4 10.8 99 2.3 10.8 2.3 1 1 0 1 1 1 0 RecT family BUD22 PF09073.10 GAM21105.1 - 0.0034 16.8 25.5 0.0034 16.8 25.5 2.5 3 0 0 3 3 3 1 BUD22 TFIIA PF03153.13 GAM21105.1 - 0.004 17.2 49.8 0.004 17.2 49.8 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF1057 PF06342.12 GAM21105.1 - 0.064 12.3 1.6 0.12 11.4 1.6 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Cwf_Cwc_15 PF04889.12 GAM21105.1 - 7.7 6.2 45.0 0.59 9.8 34.4 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TBP PF00352.21 GAM21107.1 - 3.8e-60 199.8 0.7 3.9e-31 106.9 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 GAM21107.1 - 1.4e-05 25.1 0.0 0.09 12.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 GAM21107.1 - 0.03 14.1 0.3 0.17 11.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Cmc1 PF08583.10 GAM21108.1 - 4.4e-15 55.5 8.1 6.3e-15 54.9 8.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 GAM21108.1 - 0.014 15.5 1.7 0.023 14.8 1.7 1.4 1 0 0 1 1 1 0 CHCH domain CX9C PF16860.5 GAM21108.1 - 0.029 14.4 2.3 0.049 13.6 2.3 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3128 PF11326.8 GAM21108.1 - 1.8 9.0 6.6 6.2 7.3 6.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Ribosomal_S24e PF01282.19 GAM21109.1 - 9.3e-30 102.4 1.8 1e-29 102.3 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S24e GST_N PF02798.20 GAM21110.1 - 8.3e-14 51.7 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM21110.1 - 8.1e-13 48.4 0.1 1.6e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM21110.1 - 1.5e-09 38.2 0.0 2.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM21110.1 - 1e-08 35.3 0.4 2.6e-08 34.0 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM21110.1 - 1.6e-07 31.5 0.0 3.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM21110.1 - 1.3e-05 25.1 0.1 5.9e-05 23.0 0.2 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain 5_nucleotid PF05761.14 GAM21111.1 - 3.3e-146 487.8 2.4 3.9e-146 487.6 2.4 1.1 1 0 0 1 1 1 1 5' nucleotidase family Serglycin PF04360.12 GAM21111.1 - 0.00067 19.6 6.9 0.0015 18.5 6.9 1.5 1 0 0 1 1 1 1 Serglycin DUF2967 PF11179.8 GAM21111.1 - 1.5 6.8 4.6 2.1 6.3 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Gelsolin PF00626.22 GAM21112.1 - 2.1e-40 136.4 0.1 2.2e-12 46.7 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat bPH_1 PF08000.11 GAM21112.1 - 0.1 12.7 0.0 0.85 9.7 0.0 2.4 2 1 1 3 3 3 0 Bacterial PH domain SMC_N PF02463.19 GAM21113.1 - 8.2e-41 139.8 46.4 1.8e-39 135.5 46.4 3.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAM21113.1 - 2.9e-25 88.8 0.0 1.4e-24 86.7 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAM21113.1 - 5.5e-09 36.3 12.4 3.3e-06 27.1 0.3 3.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAM21113.1 - 3.3e-07 30.4 31.0 3.3e-07 30.4 31.0 4.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 GAM21113.1 - 3.1e-05 23.6 0.0 6.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 GAM21113.1 - 0.02 15.4 0.0 0.02 15.4 0.0 6.0 4 2 0 4 4 4 0 ABC transporter DUF4062 PF13271.6 GAM21113.1 - 0.04 14.3 0.9 0.92 9.9 0.1 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) AAA_22 PF13401.6 GAM21113.1 - 0.14 12.5 5.7 11 6.3 0.0 4.3 4 0 0 4 4 4 0 AAA domain Peptidase_C1 PF00112.23 GAM21114.1 - 6.7e-48 163.7 3.9 6.7e-48 163.7 3.9 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAM21114.1 - 1.2e-05 24.3 0.6 0.00046 19.1 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family CAP PF00188.26 GAM21114.1 - 0.01 16.7 5.5 0.01 16.7 5.5 2.1 2 1 0 2 2 2 0 Cysteine-rich secretory protein family Meiosis_expr PF15163.6 GAM21114.1 - 0.14 12.8 1.2 0.8 10.4 0.0 2.4 3 0 0 3 3 3 0 Meiosis-expressed Ependymin PF00811.18 GAM21115.1 - 8.6e-09 35.7 2.0 1.2e-08 35.2 1.6 1.5 1 1 0 1 1 1 1 Ependymin DUF4209 PF13910.6 GAM21116.1 - 2.5e-22 78.9 0.0 2.1e-19 69.6 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) TRAM_LAG1_CLN8 PF03798.16 GAM21117.1 - 7.2e-21 74.8 11.2 7.2e-21 74.8 11.2 1.4 2 0 0 2 2 2 1 TLC domain FNIP PF05725.12 GAM21118.1 - 2e-88 290.3 31.0 9.1e-15 54.6 0.4 10.4 8 2 1 11 11 11 9 FNIP Repeat DUF1769 PF08588.10 GAM21118.1 - 0.17 12.1 4.6 11 6.3 0.0 4.9 5 1 0 5 5 5 0 Protein of unknown function (DUF1769) Peptidase_M20 PF01546.28 GAM21119.1 - 2.4e-20 73.1 0.0 3.6e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM21119.1 - 9.8e-12 44.8 0.0 2.9e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain PigN PF04987.14 GAM21120.1 - 1.8e-77 261.1 25.2 2.6e-77 260.6 25.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 GAM21120.1 - 1.7e-15 57.5 0.5 5.8e-12 45.9 0.5 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAM21120.1 - 2e-06 27.4 0.4 4.8e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 GAM21120.1 - 0.0016 17.9 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily EphA2_TM PF14575.6 GAM21120.1 - 0.13 13.1 0.0 0.81 10.6 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PglZ PF08665.12 GAM21120.1 - 0.15 12.2 0.0 0.67 10.0 0.1 2.0 2 0 0 2 2 2 0 PglZ domain DUF1129 PF06570.11 GAM21120.1 - 0.16 11.4 9.8 0.081 12.4 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Pkinase PF00069.25 GAM21121.1 - 1.4e-46 159.0 1.4 3e-33 115.3 0.1 2.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21121.1 - 1.5e-31 109.6 0.3 3.9e-15 55.8 0.1 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 GAM21121.1 - 0.014 14.7 0.0 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Myb_Cef PF11831.8 GAM21122.1 - 1.3e-35 123.1 7.9 1.3e-35 123.1 7.9 3.7 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 GAM21122.1 - 3.8e-21 75.0 5.2 1.5e-10 41.1 0.8 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM21122.1 - 1.7e-17 63.4 3.7 2.2e-12 47.0 3.4 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAM21122.1 - 0.061 13.5 0.4 0.29 11.3 0.1 2.3 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 GAM21122.1 - 0.2 11.8 0.2 0.2 11.8 0.2 2.9 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Mobilization_B PF17511.2 GAM21122.1 - 1.5 9.2 5.8 0.35 11.3 1.0 2.4 2 0 0 2 2 2 0 Mobilization protein B PHM7_cyt PF14703.6 GAM21123.1 - 0.0024 18.1 0.3 0.34 11.1 0.3 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 GAM21123.1 - 0.0028 17.0 26.6 0.0028 17.0 26.6 2.6 3 1 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate TM140 PF14985.6 GAM21123.1 - 0.05 13.1 0.0 0.05 13.1 0.0 2.8 3 0 0 3 3 3 0 TM140 protein family Glyco_hydro_25 PF01183.20 GAM21124.1 - 1.2e-10 41.8 0.1 1.4e-10 41.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 DUF1906 PF08924.11 GAM21124.1 - 0.0099 16.0 3.6 0.014 15.5 3.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1906) Peptidase_S24 PF00717.23 GAM21125.1 - 8.4e-08 32.1 0.1 1.3e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like GATA PF00320.27 GAM21126.1 - 1.4e-15 56.6 3.7 4e-15 55.1 3.7 1.8 1 0 0 1 1 1 1 GATA zinc finger Cytochrom_c3_2 PF14537.6 GAM21126.1 - 2.3 8.7 9.7 0.68 10.4 5.7 2.2 2 0 0 2 2 2 0 Cytochrome c3 TIG PF01833.24 GAM21127.1 - 3.6e-20 71.8 52.6 7.4e-05 22.7 4.0 9.6 9 0 0 9 9 9 7 IPT/TIG domain Lectin_C PF00059.21 GAM21127.1 - 0.0035 18.1 0.8 0.011 16.5 0.3 2.1 2 0 0 2 2 2 1 Lectin C-type domain EGF_2 PF07974.13 GAM21127.1 - 0.012 15.9 11.8 0.012 15.9 11.8 2.2 2 0 0 2 2 2 0 EGF-like domain EGF PF00008.27 GAM21127.1 - 1.3 9.4 6.5 4.2 7.8 6.5 1.9 1 0 0 1 1 1 0 EGF-like domain EMP70 PF02990.16 GAM21130.1 - 3.7e-204 679.2 11.6 5.4e-204 678.7 11.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 RRM_1 PF00076.22 GAM21131.1 - 1.8e-23 82.1 0.3 4.1e-11 42.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM21131.1 - 1.5e-06 27.8 0.1 0.0055 16.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM21131.1 - 4.3e-05 23.3 0.0 0.0058 16.5 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 GAM21131.1 - 0.00081 19.3 0.1 0.0018 18.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) Limkain-b1 PF11608.8 GAM21131.1 - 0.0023 18.0 0.3 0.016 15.3 0.1 2.3 2 0 0 2 2 2 1 Limkain b1 RNase_T PF00929.24 GAM21132.1 - 1.8e-09 38.3 0.2 6.3e-09 36.6 0.2 2.0 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 GAM21132.1 - 0.016 14.9 0.2 0.06 13.0 0.2 1.9 1 1 0 1 1 1 0 3'-5' exonuclease Annexin PF00191.20 GAM21132.1 - 0.31 11.2 2.0 0.64 10.1 0.2 2.6 2 0 0 2 2 2 0 Annexin DUF3837 PF12939.7 GAM21132.1 - 0.7 10.3 5.5 0.46 10.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) EloA-BP1 PF15870.5 GAM21132.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.8 4 0 0 4 4 4 0 ElonginA binding-protein 1 MFS_1 PF07690.16 GAM21133.1 - 6.3e-15 55.0 37.2 1.6e-12 47.0 5.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM21133.1 - 4.3e-11 42.0 25.8 1.6e-10 40.1 6.7 2.6 2 1 0 3 3 3 2 MFS/sugar transport protein PUCC PF03209.15 GAM21133.1 - 5.3e-06 25.7 1.1 5.3e-06 25.7 1.1 2.4 2 1 1 3 3 3 1 PUCC protein zf-C3HC4_2 PF13923.6 GAM21134.1 - 0.0019 18.0 0.0 0.0041 16.9 0.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM21134.1 - 0.0059 16.4 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ApoL PF05461.11 GAM21134.1 - 0.015 14.6 5.4 0.025 13.9 5.4 1.4 1 0 0 1 1 1 0 Apolipoprotein L Cpn60_TCP1 PF00118.24 GAM21135.1 - 1.6e-162 541.6 11.5 1.9e-162 541.4 11.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RhoGAP PF00620.27 GAM21136.1 - 1.9e-45 154.4 0.2 4.2e-45 153.3 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 GAM21136.1 - 7.5e-26 90.9 2.6 2.3e-18 66.7 1.0 2.5 1 1 1 2 2 2 2 Divergent CRAL/TRIO domain IPK PF03770.16 GAM21137.1 - 2.5e-43 148.3 0.1 2.5e-43 148.3 0.1 1.3 2 0 0 2 2 2 1 Inositol polyphosphate kinase STD1 PF17235.2 GAM21137.1 - 0.057 13.1 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 STD1/MTH1 LMF1 PF06762.14 GAM21138.1 - 3.6e-47 161.5 7.6 5.8e-41 141.0 0.3 2.3 1 1 1 2 2 2 2 Lipase maturation factor PHP PF02811.19 GAM21139.1 - 2.9e-05 24.4 0.0 0.00012 22.4 0.0 1.7 1 1 0 1 1 1 1 PHP domain LRR_1 PF00560.33 GAM21140.1 - 2e-07 30.6 12.2 0.65 10.8 0.8 7.9 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.7 GAM21140.1 - 1.5e-05 25.2 12.4 0.78 10.3 0.1 6.0 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAM21140.1 - 7e-05 22.6 13.2 2.6 8.3 0.0 7.4 8 0 0 8 8 8 2 Leucine Rich repeat Mannitol_dh_C PF08125.13 GAM21141.1 - 7.8e-71 238.4 0.0 1.1e-70 238.0 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 GAM21141.1 - 1.2e-22 80.7 0.7 3.5e-22 79.2 0.7 1.8 1 1 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain AAA PF00004.29 GAM21142.1 - 8.2e-12 45.7 0.5 6.1e-11 42.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAM21142.1 - 1.6e-08 34.7 0.2 3e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_14 PF13173.6 GAM21142.1 - 5.9e-06 26.3 0.0 4.3e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAM21142.1 - 0.0001 22.1 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 GAM21142.1 - 0.00011 22.0 0.2 0.00011 22.0 0.2 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 GAM21142.1 - 0.00018 21.8 0.1 0.0075 16.6 0.1 2.9 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 GAM21142.1 - 0.00058 20.1 0.1 0.0026 18.0 0.1 2.2 1 0 0 1 1 1 1 AAA C-terminal domain AAA_28 PF13521.6 GAM21142.1 - 0.0033 17.7 0.9 0.0052 17.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 GAM21142.1 - 0.0039 17.7 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAM21142.1 - 0.0043 16.4 0.0 0.0097 15.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin PDE4_UCR PF18100.1 GAM21142.1 - 0.012 16.2 0.8 0.012 16.2 0.8 2.6 3 0 0 3 3 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) ABC_tran PF00005.27 GAM21142.1 - 0.014 15.9 2.5 0.36 11.3 0.0 3.8 4 0 0 4 4 4 0 ABC transporter PhaP_Bmeg PF09602.10 GAM21142.1 - 0.025 14.5 0.1 0.025 14.5 0.1 2.5 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ATPase PF06745.13 GAM21142.1 - 0.025 13.9 3.2 0.049 13.0 0.2 2.8 2 1 1 3 3 3 0 KaiC AAA_24 PF13479.6 GAM21142.1 - 0.033 13.9 0.2 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAM21142.1 - 0.034 14.1 0.1 0.27 11.2 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 GAM21142.1 - 0.036 14.2 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM21142.1 - 0.038 14.4 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Pilt PF15453.6 GAM21142.1 - 0.039 13.4 7.3 0.065 12.6 6.0 1.9 2 0 0 2 2 2 0 Protein incorporated later into Tight Junctions AAA_16 PF13191.6 GAM21142.1 - 0.04 14.3 0.7 0.11 12.9 0.0 2.1 2 1 0 2 2 1 0 AAA ATPase domain AAA_5 PF07728.14 GAM21142.1 - 0.049 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 GAM21142.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 GAM21142.1 - 0.056 13.2 0.0 0.19 11.4 0.0 2.0 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 GAM21142.1 - 0.088 12.9 0.1 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 GAM21142.1 - 0.1 12.1 0.1 0.33 10.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAM21142.1 - 0.17 10.9 3.5 0.33 10.0 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_19 PF13245.6 GAM21142.1 - 0.31 11.4 6.7 0.12 12.8 0.5 3.0 3 1 1 4 4 3 0 AAA domain RasGAP PF00616.19 GAM21145.1 - 3.4e-24 85.7 0.1 2.6e-22 79.6 0.0 3.2 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.18 GAM21145.1 - 1.2e-22 80.1 0.4 4.8e-22 78.2 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 GAM21145.1 - 0.00049 20.4 0.3 0.0018 18.6 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CTV_P33 PF07184.11 GAM21145.1 - 0.093 11.8 0.4 0.18 10.9 0.4 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein DUF313 PF03754.13 GAM21145.1 - 0.13 12.5 1.6 0.41 10.9 1.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF313) WRKY PF03106.15 GAM21146.1 - 3.4e-33 113.7 21.5 1.2e-18 67.1 10.1 2.3 2 0 0 2 2 2 2 WRKY DNA -binding domain PBP1_TM PF14812.6 GAM21147.1 - 0.088 13.2 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 GAM21149.1 - 1.3e-48 165.6 6.3 2.3e-32 112.4 0.0 5.2 4 1 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21149.1 - 1.4e-23 83.5 0.0 6.4e-13 48.6 0.0 3.8 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 GAM21149.1 - 4.3e-15 56.0 0.0 3.3e-14 53.1 0.0 2.7 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 GAM21149.1 - 1.3e-14 54.3 4.2 1.6e-14 53.9 0.0 3.1 3 1 0 3 3 3 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.7 GAM21149.1 - 6e-12 45.6 0.2 6e-12 45.6 0.2 6.7 7 1 1 8 8 8 1 Anticodon binding domain of tRNAs HGTP_anticodon PF03129.20 GAM21149.1 - 1.3e-07 31.6 0.1 1.1e-06 28.7 0.1 2.5 2 0 0 2 2 2 1 Anticodon binding domain Kinase-like PF14531.6 GAM21149.1 - 0.00032 20.1 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like KH_1 PF00013.29 GAM21150.1 - 4.4e-14 52.0 0.5 8.3e-14 51.2 0.5 1.5 1 0 0 1 1 1 1 KH domain DUF1771 PF08590.10 GAM21150.1 - 4.6e-10 39.7 11.9 4.6e-10 39.7 11.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 GAM21150.1 - 3.2e-07 30.6 0.0 9.6e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Smr domain AAA_11 PF13086.6 GAM21150.1 - 0.0014 18.5 4.4 0.002 18.0 4.4 1.3 1 0 0 1 1 1 1 AAA domain DUF4407 PF14362.6 GAM21150.1 - 0.024 14.0 15.1 0.042 13.2 15.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KH_2 PF07650.17 GAM21150.1 - 0.18 11.7 0.3 0.18 11.7 0.3 1.9 2 0 0 2 2 2 0 KH domain Rep_4 PF05797.11 GAM21150.1 - 0.49 9.5 5.2 0.66 9.0 5.2 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Mito_carr PF00153.27 GAM21151.1 - 9e-61 201.8 0.8 9.9e-21 73.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAM21151.1 - 0.006 15.8 0.1 2.7 7.1 0.0 2.6 2 0 0 2 2 2 2 Gammaproteobacterial serine protease CRAL_TRIO PF00650.20 GAM21152.1 - 4e-47 159.9 0.1 6.1e-47 159.3 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM21152.1 - 3.9e-10 39.8 0.8 8.3e-10 38.7 0.8 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAM21152.1 - 1.7e-09 37.9 0.1 2.4e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Peptidase_M50 PF02163.22 GAM21153.1 - 6.4e-12 45.3 2.7 3e-10 39.8 2.7 2.3 1 1 0 1 1 1 1 Peptidase family M50 DUF1996 PF09362.10 GAM21154.1 - 1.3e-35 123.5 0.2 2e-35 122.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) LRRNT PF01462.18 GAM21154.1 - 0.041 13.6 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain TIG PF01833.24 GAM21155.1 - 1.3e-41 140.6 191.7 1.3e-07 31.6 4.2 17.9 12 5 4 18 18 18 13 IPT/TIG domain EGF_2 PF07974.13 GAM21155.1 - 0.0011 19.3 12.6 0.0023 18.3 12.6 1.6 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 GAM21155.1 - 0.012 15.9 10.5 0.032 14.6 10.5 1.8 1 0 0 1 1 1 0 EGF-like domain LDB19 PF13002.7 GAM21155.1 - 0.041 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Arrestin_N terminal like hEGF PF12661.7 GAM21155.1 - 0.32 11.7 8.6 1 10.1 8.6 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF EB PF01683.18 GAM21155.1 - 0.37 11.1 7.5 0.95 9.8 7.5 1.6 1 0 0 1 1 1 0 EB module TIG PF01833.24 GAM21156.1 - 2.5e-48 162.1 146.2 4.7e-07 29.8 6.1 13.2 11 2 2 13 13 13 10 IPT/TIG domain SH3_19 PF18597.1 GAM21156.1 - 0.0036 17.1 4.2 0.19 11.6 0.3 3.7 3 0 0 3 3 3 2 Myosin X N-terminal SH3 domain FliMN_C PF01052.20 GAM21156.1 - 0.018 15.0 0.1 0.72 9.9 0.0 2.8 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term TIG PF01833.24 GAM21157.1 - 2.2e-20 72.5 116.7 1.2e-06 28.4 1.7 12.3 6 4 4 10 10 10 8 IPT/TIG domain EGF_2 PF07974.13 GAM21157.1 - 0.00099 19.4 12.5 0.0021 18.4 12.5 1.5 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 GAM21157.1 - 0.25 11.7 6.6 0.6 10.4 6.6 1.6 1 0 0 1 1 1 0 EB module EGF PF00008.27 GAM21157.1 - 0.43 10.9 8.8 1.1 9.6 8.8 1.7 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 GAM21157.1 - 1 10.1 7.5 3.4 8.4 7.5 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF TIG PF01833.24 GAM21158.1 - 1.9e-66 220.2 231.6 3.3e-07 30.3 4.7 21.8 12 5 11 23 23 23 19 IPT/TIG domain EB PF01683.18 GAM21158.1 - 0.019 15.3 5.6 0.055 13.8 5.6 1.8 1 0 0 1 1 1 0 EB module EGF PF00008.27 GAM21158.1 - 0.28 11.5 9.1 0.75 10.2 9.1 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 GAM21158.1 - 0.73 10.2 12.1 1.6 9.2 12.1 1.6 1 0 0 1 1 1 0 EGF-like domain FAA_hydrolase PF01557.18 GAM21161.1 - 7.9e-60 202.2 0.0 9.7e-60 201.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 GAM21161.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 KH domain SRP54 PF00448.22 GAM21162.1 - 7.3e-77 257.4 1.1 1.3e-76 256.6 1.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 GAM21162.1 - 3.3e-25 88.6 0.8 3.3e-25 88.6 0.8 4.6 4 1 1 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.19 GAM21162.1 - 1.2e-11 44.6 2.2 1.2e-11 44.6 2.2 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain cobW PF02492.19 GAM21162.1 - 1.6e-06 27.8 1.4 3.3e-05 23.5 1.4 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 GAM21162.1 - 8.9e-05 22.5 0.2 0.00024 21.1 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 GAM21162.1 - 9.1e-05 22.7 0.0 0.00023 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 GAM21162.1 - 9.7e-05 21.9 0.2 0.11 11.9 0.1 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit CbiA PF01656.23 GAM21162.1 - 0.0001 22.4 0.0 0.00062 19.8 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 GAM21162.1 - 0.00037 19.6 0.4 0.0014 17.7 0.1 2.0 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAM21162.1 - 0.00095 19.6 0.0 0.0015 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GAM21162.1 - 0.00099 19.5 0.7 0.0094 16.4 0.7 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 GAM21162.1 - 0.0017 18.8 1.1 0.0031 17.9 0.1 2.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 GAM21162.1 - 0.0018 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 GAM21162.1 - 0.0028 17.6 0.2 0.015 15.2 0.2 2.2 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 GAM21162.1 - 0.003 17.5 0.1 0.013 15.4 0.0 2.1 3 0 0 3 3 2 1 Adenylylsulphate kinase CLP1_P PF16575.5 GAM21162.1 - 0.0063 16.3 0.3 0.56 10.0 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Thymidylate_kin PF02223.17 GAM21162.1 - 0.015 15.0 0.3 0.06 13.0 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.6 GAM21162.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 GAM21162.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2209 PF09974.9 GAM21162.1 - 0.026 14.8 0.3 0.064 13.6 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Zeta_toxin PF06414.12 GAM21162.1 - 0.027 13.7 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 GAM21162.1 - 0.036 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Roc PF08477.13 GAM21162.1 - 0.042 14.1 0.1 0.11 12.8 0.1 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 GAM21162.1 - 0.055 13.7 0.1 0.14 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 GAM21162.1 - 0.09 12.2 0.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family NTPase_1 PF03266.15 GAM21162.1 - 0.17 11.8 2.2 2.9 7.8 2.2 2.3 1 1 0 1 1 1 0 NTPase Metallophos PF00149.28 GAM21163.1 - 1.9e-41 142.9 0.1 2.3e-41 142.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAM21163.1 - 2.1e-16 60.1 1.3 5.3e-16 58.8 0.7 2.0 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain ABC_tran PF00005.27 GAM21164.1 - 7.1e-26 91.3 0.0 1.1e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAM21164.1 - 7.4e-23 81.2 29.3 1.1e-22 80.7 29.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAM21164.1 - 4.2e-12 46.5 0.9 7.2e-08 32.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAM21164.1 - 0.00027 21.5 0.0 0.00059 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 GAM21164.1 - 0.0024 18.0 0.0 0.043 14.1 0.0 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 GAM21164.1 - 0.0081 15.6 0.1 0.28 10.6 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 GAM21164.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAM21164.1 - 0.019 14.7 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 GAM21164.1 - 0.053 13.3 0.0 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DctQ PF04290.12 GAM21164.1 - 8.1 6.4 8.3 25 4.8 5.4 2.6 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component VPS9 PF02204.18 GAM21165.1 - 3.2e-20 72.3 0.0 7.8e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Vps8 PF12816.7 GAM21166.1 - 4.2e-53 179.8 5.5 4.2e-53 179.8 5.5 3.8 3 2 1 4 4 4 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 GAM21166.1 - 2.8e-13 50.0 14.0 1.2e-07 31.7 0.4 4.1 4 0 0 4 4 4 3 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 GAM21166.1 - 0.0001 22.2 4.0 0.00026 21.0 4.0 1.7 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 GAM21166.1 - 0.0054 16.7 5.0 0.011 15.7 5.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ANAPC4_WD40 PF12894.7 GAM21166.1 - 0.14 12.4 0.0 8 6.8 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-rbx1 PF12678.7 GAM21166.1 - 0.15 12.4 4.8 0.34 11.2 4.8 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain WD40 PF00400.32 GAM21166.1 - 0.16 12.9 1.8 2.8 8.9 0.2 3.8 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 GAM21166.1 - 0.51 10.2 3.3 1.4 8.9 3.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM21166.1 - 0.52 10.7 5.8 1.4 9.3 5.8 1.8 1 0 0 1 1 1 0 Ring finger domain CCDC24 PF15669.5 GAM21166.1 - 0.68 9.8 9.0 0.55 10.1 1.8 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family zf-C3HC4 PF00097.25 GAM21166.1 - 2.7 7.9 6.0 6.3 6.8 6.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM21166.1 - 6.8 6.6 6.1 11 6.0 2.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FlgT_N PF16548.5 GAM21168.1 - 0.34 11.5 2.0 0.46 11.1 0.2 2.2 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain Sulfate_transp PF00916.20 GAM21169.1 - 1e-99 333.9 18.8 1.4e-99 333.4 18.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAM21169.1 - 3e-17 62.3 0.3 4.7e-17 61.7 0.3 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAM21169.1 - 0.00037 20.9 1.7 0.00037 20.9 1.7 3.4 3 2 0 3 3 3 1 Molybdate transporter of MFS superfamily AzlD PF05437.12 GAM21169.1 - 0.12 12.6 14.3 0.1 12.8 4.9 3.8 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) A_deaminase PF00962.22 GAM21170.1 - 1.5e-118 395.9 0.2 2.2e-118 395.4 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase IF4E PF01652.18 GAM21172.1 - 2.4e-27 95.7 6.8 2.4e-27 95.7 6.8 2.4 3 0 0 3 3 3 1 Eukaryotic initiation factor 4E AAA PF00004.29 GAM21173.1 - 0.053 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Kelch_6 PF13964.6 GAM21174.1 - 6.6e-07 29.4 9.6 0.067 13.5 0.9 5.9 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.6 GAM21174.1 - 8e-06 25.8 5.3 2.1 8.4 0.0 5.2 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM21174.1 - 0.011 15.2 4.5 1.1 8.9 0.1 4.7 4 0 0 4 4 4 0 Kelch motif DEAD PF00270.29 GAM21175.1 - 1.6e-16 60.6 1.5 1.3e-15 57.6 0.1 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM21175.1 - 2.5e-13 50.4 0.4 3.5e-12 46.7 0.4 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM21175.1 - 2.8e-06 27.4 0.0 8e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 GAM21175.1 - 4.2e-05 24.1 0.0 0.00015 22.3 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.6 GAM21175.1 - 0.0016 18.7 0.1 0.0038 17.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) DNA_pol_lambd_f PF10391.9 GAM21175.1 - 0.0023 17.7 0.0 0.0076 16.1 0.0 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Lectin_N PF03954.14 GAM21175.1 - 0.077 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DNAPolymera_Pol PF11590.8 GAM21175.1 - 0.19 11.6 0.1 0.52 10.2 0.1 1.7 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol ALG3 PF05208.13 GAM21177.1 - 2.2e-143 478.0 20.9 2.6e-143 477.8 20.9 1.0 1 0 0 1 1 1 1 ALG3 protein Mannosyl_trans PF05007.13 GAM21177.1 - 0.0085 16.0 1.6 0.0085 16.0 1.6 3.4 3 1 0 3 3 3 2 Mannosyltransferase (PIG-M) Cortexin PF11057.8 GAM21177.1 - 0.066 13.1 0.9 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Cortexin of kidney DUF4637 PF15470.6 GAM21178.1 - 0.031 14.0 0.1 0.035 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) cNMPbd_u2 PF16643.5 GAM21178.1 - 0.088 13.3 2.4 0.11 13.0 2.0 1.4 1 1 0 1 1 1 0 Unstructured region on cNMP-binding protein Guanylate_cyc PF00211.20 GAM21179.1 - 2e-27 96.0 0.2 2e-27 96.0 0.2 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Response_reg PF00072.24 GAM21179.1 - 8.6e-21 74.2 0.1 4.3e-12 46.2 0.0 3.0 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.26 GAM21179.1 - 5.8e-12 46.1 0.8 7.4e-11 42.5 0.8 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_2 PF07719.17 GAM21179.1 - 0.0092 16.0 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM21179.1 - 0.026 14.4 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_9 PF14580.6 GAM21180.1 - 1.8e-15 56.9 4.1 5.1e-15 55.4 4.1 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 GAM21180.1 - 2.3e-10 40.5 15.1 1.8e-05 25.0 3.3 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM21180.1 - 4.4e-07 29.6 13.0 4.4e-05 23.2 0.2 3.3 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 GAM21180.1 - 0.25 11.5 19.1 0.38 10.9 1.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeat ABC2_membrane PF01061.24 GAM21181.1 - 1.9e-31 109.1 23.5 3e-31 108.5 23.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAM21181.1 - 7.8e-26 91.2 0.0 1.4e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM21181.1 - 3.3e-05 23.8 0.1 0.0083 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAM21181.1 - 0.00085 19.7 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM21181.1 - 0.0018 18.2 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_2 PF12679.7 GAM21181.1 - 0.0035 16.7 3.3 0.0065 15.8 3.3 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_33 PF13671.6 GAM21181.1 - 0.0037 17.4 0.0 0.0068 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GAM21181.1 - 0.0074 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAM21181.1 - 0.0083 15.8 0.4 0.019 14.7 0.4 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GAM21181.1 - 0.0097 16.2 0.2 0.054 13.8 0.1 2.2 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 GAM21181.1 - 0.021 15.1 0.2 0.036 14.3 0.2 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 GAM21181.1 - 0.026 14.0 0.1 4 6.8 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 GAM21181.1 - 0.028 15.0 0.0 0.057 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAM21181.1 - 0.03 14.4 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 GAM21181.1 - 0.032 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 GAM21181.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 GAM21181.1 - 0.058 13.0 0.1 0.094 12.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2791 PF10923.8 GAM21181.1 - 0.063 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) DLIC PF05783.11 GAM21181.1 - 0.072 11.9 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_30 PF13604.6 GAM21181.1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAM21181.1 - 0.15 12.0 0.2 2.2 8.2 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 GAM21181.1 - 0.18 11.5 0.2 0.45 10.2 0.1 1.6 2 0 0 2 2 2 0 AAA domain TIG PF01833.24 GAM21182.1 - 1.1e-16 60.7 51.0 2.2e-05 24.5 1.6 9.3 8 1 1 9 9 9 5 IPT/TIG domain EGF_2 PF07974.13 GAM21182.1 - 0.0018 18.6 12.9 0.0039 17.5 12.9 1.6 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 GAM21182.1 - 0.14 12.3 11.4 0.31 11.1 11.4 1.6 1 0 0 1 1 1 0 Tenascin EGF domain Toxin_2 PF00451.19 GAM21182.1 - 7.2 7.0 10.2 9.8 6.6 6.6 2.5 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 DAP3 PF10236.9 GAM21185.1 - 2.5e-05 23.6 0.0 0.0055 15.9 0.0 2.3 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 SAM_1 PF00536.30 GAM21185.1 - 0.0001 22.7 0.0 0.00024 21.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_16 PF13191.6 GAM21185.1 - 0.012 16.0 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SAM_PNT PF02198.16 GAM21185.1 - 0.039 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain AAA_14 PF13173.6 GAM21185.1 - 0.1 12.6 0.0 2.6 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain Peptidase_C5 PF00770.18 GAM21186.1 - 0.007 16.1 0.0 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 Adenovirus endoprotease DUF4196 PF13846.6 GAM21187.1 - 0.11 12.7 4.9 0.23 11.7 4.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4196) LRR_RI_capping PF18779.1 GAM21188.1 - 0.044 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat KAP_NTPase PF07693.14 GAM21188.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Glyco_transf_41 PF13844.6 GAM21190.1 - 1.2e-53 182.2 0.5 4.9e-27 94.5 0.1 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 GAM21190.1 - 8.1e-35 117.2 17.6 1.8e-08 33.9 0.0 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21190.1 - 4.7e-29 98.1 11.8 3.7e-06 26.6 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAM21190.1 - 4.3e-27 92.0 5.0 8.2e-06 25.6 0.0 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAM21190.1 - 6.7e-25 86.5 25.3 5.8e-06 25.9 3.5 6.9 2 2 5 7 7 7 5 TPR repeat TPR_7 PF13176.6 GAM21190.1 - 5.5e-20 69.9 15.8 0.00087 19.2 0.0 6.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAM21190.1 - 8.6e-20 70.8 11.7 2.7e-08 34.0 0.0 5.0 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAM21190.1 - 4.9e-19 68.7 7.7 3.1e-08 34.1 0.2 4.5 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAM21190.1 - 6.1e-18 63.8 20.6 0.0057 16.9 1.6 7.6 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAM21190.1 - 1.3e-14 53.6 1.7 0.14 13.0 0.0 6.0 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 GAM21190.1 - 2e-14 52.9 20.5 0.0027 17.5 0.0 6.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 GAM21190.1 - 2.5e-11 43.4 9.2 0.15 12.7 0.1 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM21190.1 - 3.6e-11 43.4 11.1 1e-05 25.9 1.7 4.4 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAM21190.1 - 1.3e-06 28.4 4.1 0.11 12.6 0.0 4.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 GAM21190.1 - 0.00048 20.5 2.6 6.2 7.7 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat RPN7 PF10602.9 GAM21190.1 - 0.0015 18.2 3.7 1.6 8.4 0.4 3.9 1 1 2 4 4 4 1 26S proteasome subunit RPN7 NARP1 PF12569.8 GAM21190.1 - 0.002 17.2 3.2 0.12 11.3 0.0 3.1 1 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 GAM21190.1 - 0.0044 16.4 0.0 0.022 14.1 0.1 2.0 2 1 0 2 2 2 1 MalT-like TPR region EST1_DNA_bind PF10373.9 GAM21190.1 - 0.11 12.0 4.2 6.2 6.2 1.2 3.5 1 1 2 3 3 3 0 Est1 DNA/RNA binding domain NAD_binding_3 PF03447.16 GAM21190.1 - 0.16 12.6 0.2 21 5.8 0.0 2.4 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain DUF4810 PF16068.5 GAM21190.1 - 0.39 11.3 3.4 41 4.8 0.0 4.2 5 1 0 5 5 3 0 Domain of unknown function (DUF4810) MIT PF04212.18 GAM21190.1 - 7.5 6.7 9.5 45 4.2 0.0 4.9 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain FNIP PF05725.12 GAM21192.1 - 5.3e-77 253.8 17.3 5.4e-14 52.1 0.1 9.3 6 2 5 11 11 11 11 FNIP Repeat RRM_1 PF00076.22 GAM21193.1 - 0.018 14.9 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRN3 PF05327.11 GAM21193.1 - 2.1 6.8 20.6 0.28 9.7 12.7 2.0 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 GWT1 PF06423.12 GAM21194.1 - 1.6e-28 99.7 8.0 1.6e-28 99.7 8.0 3.1 3 1 0 3 3 3 1 GWT1 DUF1686 PF07937.11 GAM21194.1 - 0.079 12.8 1.0 0.23 11.3 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1686) TRAM1 PF08390.11 GAM21194.1 - 0.61 9.8 3.7 0.72 9.6 0.1 2.7 2 0 0 2 2 2 0 TRAM1-like protein Pur_ac_phosph_N PF16656.5 GAM21195.1 - 2.8e-17 63.0 1.3 6.2e-17 62.0 1.3 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain ATP19 PF11022.8 GAM21195.1 - 0.0089 16.4 0.1 0.04 14.3 0.0 2.1 2 0 0 2 2 2 1 ATP synthase subunit K UbiA PF01040.18 GAM21195.1 - 0.077 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF2369 PF10179.9 GAM21195.1 - 0.32 11.4 3.0 1.5 9.2 3.0 2.1 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) G_glu_transpept PF01019.21 GAM21196.1 - 6.7e-135 450.8 0.0 3.7e-83 280.1 0.0 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase DUF5331 PF17265.2 GAM21196.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5331) Methyltransf_25 PF13649.6 GAM21197.1 - 1.7e-05 25.4 0.0 6e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 GAM21197.1 - 4.4e-05 23.0 0.0 8.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_12 PF08242.12 GAM21197.1 - 8.4e-05 23.2 0.0 0.00018 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM21197.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DUF5370 PF17340.2 GAM21197.1 - 0.021 14.7 0.4 0.069 13.0 0.4 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5370) Methyltransf_11 PF08241.12 GAM21197.1 - 0.12 13.1 0.0 0.63 10.7 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain SAYSvFN PF10260.9 GAM21198.1 - 1.4e-08 34.5 2.3 2.2e-08 33.9 2.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) AAA_11 PF13086.6 GAM21199.1 - 2.8e-60 204.3 0.0 2.8e-60 204.3 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.6 GAM21199.1 - 6.5e-60 202.2 0.1 1.9e-59 200.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain SEN1_N PF12726.7 GAM21199.1 - 1.1e-23 83.4 1.6 1.5e-22 79.7 1.6 2.4 1 1 0 1 1 1 1 SEN1 N terminal AAA_30 PF13604.6 GAM21199.1 - 7.7e-12 45.3 0.0 3.3e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAM21199.1 - 7.7e-10 39.3 0.0 2.6e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAM21199.1 - 4.7e-05 23.2 0.1 0.31 10.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 GAM21199.1 - 0.0026 17.3 6.2 0.017 14.7 0.0 3.9 4 1 0 5 5 5 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 GAM21199.1 - 0.01 16.3 0.1 0.078 13.4 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain ResIII PF04851.15 GAM21199.1 - 0.017 15.1 0.0 0.097 12.7 0.0 2.3 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAM21199.1 - 0.025 14.8 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 GAM21199.1 - 0.046 13.6 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Helicase AAA PF00004.29 GAM21199.1 - 0.049 14.0 0.1 0.31 11.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM21199.1 - 0.089 12.8 0.1 0.25 11.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 GAM21199.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ANAPC3 PF12895.7 GAM21200.1 - 1.9e-05 24.8 2.6 0.0039 17.4 0.1 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAM21200.1 - 0.00073 20.1 0.6 0.0069 17.0 0.5 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM21200.1 - 0.0027 17.3 0.6 0.0068 16.1 0.6 1.6 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.6 GAM21200.1 - 0.0038 17.9 0.1 0.0097 16.7 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM21200.1 - 0.0056 16.5 0.4 0.0056 16.5 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM21200.1 - 0.019 15.4 0.7 0.045 14.3 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM21200.1 - 0.2 12.4 1.0 4 8.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM21200.1 - 0.29 11.4 0.1 0.29 11.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5588 PF17826.1 GAM21200.1 - 0.3 9.9 4.3 2.4 7.0 0.1 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5588) TPR_2 PF07719.17 GAM21200.1 - 0.95 9.7 10.5 0.24 11.6 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA_edit PF04073.15 GAM21201.1 - 9.9e-05 22.4 0.0 0.0035 17.4 0.0 2.2 2 0 0 2 2 2 2 Aminoacyl-tRNA editing domain Ras PF00071.22 GAM21202.1 - 2.4e-49 167.1 0.0 3.2e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM21202.1 - 7.1e-23 81.1 0.0 1.2e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM21202.1 - 2.4e-09 36.9 0.0 3.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM21202.1 - 0.0013 18.2 0.0 0.0028 17.1 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Lipase_GDSL_3 PF14606.6 GAM21202.1 - 0.022 14.9 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family GTP_EFTU PF00009.27 GAM21202.1 - 0.074 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Glycos_transf_2 PF00535.26 GAM21203.1 - 1.7e-14 54.0 0.0 3.5e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 GAM21203.1 - 6.1e-07 29.2 0.1 1.1e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 GAM21203.1 - 5.4e-05 23.6 0.1 0.00018 22.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 RhoGAP PF00620.27 GAM21204.1 - 1.8e-32 112.3 0.0 3.3e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RPEL PF02755.15 GAM21204.1 - 0.0028 17.3 0.0 0.0063 16.2 0.0 1.6 1 0 0 1 1 1 1 RPEL repeat FtsX PF02687.21 GAM21205.1 - 1.6e-14 54.1 22.2 3.1e-09 37.2 7.3 5.9 6 0 0 6 6 6 3 FtsX-like permease family DUF3246 PF11596.8 GAM21205.1 - 0.013 15.0 8.0 0.03 13.8 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Evr1_Alr PF04777.13 GAM21206.1 - 3.8e-11 43.3 0.0 9.6e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Erv1 / Alr family HutD PF05962.11 GAM21207.1 - 3.4e-24 85.8 0.1 9.2e-22 77.9 0.0 2.7 2 1 0 2 2 2 2 HutD PRIMA1 PF16101.5 GAM21207.1 - 0.14 12.2 1.8 0.26 11.3 1.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DcpS_C PF11969.8 GAM21208.1 - 5.5e-26 91.3 0.3 7.3e-26 90.9 0.3 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 GAM21208.1 - 1.6e-13 51.2 0.2 2.6e-13 50.5 0.2 1.3 1 0 0 1 1 1 1 HIT domain MCM PF00493.23 GAM21209.1 - 4.6e-102 339.9 0.1 7.2e-102 339.2 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAM21209.1 - 3.5e-36 123.8 0.1 8.2e-36 122.6 0.1 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAM21209.1 - 6.3e-27 93.8 2.3 9.4e-27 93.3 1.1 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 GAM21209.1 - 8.8e-13 48.8 0.9 2.7e-12 47.2 0.4 2.2 2 0 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAM21209.1 - 1.7e-09 37.4 0.0 5.4e-08 32.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAM21209.1 - 5.4e-07 29.7 0.0 1.3e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAM21209.1 - 6.5e-05 22.8 0.0 0.001 19.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 GAM21209.1 - 0.00053 19.8 1.0 0.0021 17.8 0.4 2.4 2 0 0 2 2 2 1 AAA lid domain Sigma54_activat PF00158.26 GAM21209.1 - 0.0045 16.7 0.1 0.033 13.9 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain SBDS_C PF09377.10 GAM21209.1 - 0.097 12.7 0.2 0.38 10.8 0.2 2.0 1 0 0 1 1 1 0 SBDS protein C-terminal domain AAA PF00004.29 GAM21209.1 - 0.12 12.8 0.1 0.89 10.0 0.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MCM2_N PF12619.8 GAM21209.1 - 2.3 8.5 64.6 0.2 11.9 53.1 3.9 2 1 2 4 4 3 0 Mini-chromosome maintenance protein 2 RRM_1 PF00076.22 GAM21210.1 - 3.2e-24 84.5 3.3 1.4e-08 34.4 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM21210.1 - 0.011 15.4 0.0 0.68 9.5 0.0 2.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAM21210.1 - 0.05 13.6 0.1 13 5.9 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif RasGEF PF00617.19 GAM21211.1 - 3.1e-39 135.0 0.3 3.1e-39 135.0 0.3 2.1 2 0 0 2 2 2 1 RasGEF domain LRR_8 PF13855.6 GAM21211.1 - 4.5e-19 68.0 33.0 2e-08 33.9 5.1 6.3 4 2 2 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 GAM21211.1 - 8.3e-13 48.3 45.0 1e-05 25.7 3.8 8.2 8 1 1 9 9 9 4 Leucine Rich repeats (2 copies) RasGEF_N PF00618.20 GAM21211.1 - 1.2e-10 41.5 0.5 7e-10 39.1 0.5 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif LRR_9 PF14580.6 GAM21211.1 - 0.0009 18.8 12.2 0.095 12.2 1.3 3.1 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 GAM21211.1 - 0.12 12.9 0.0 0.12 12.9 0.0 9.6 10 0 0 10 10 10 0 Leucine Rich Repeat FAD-oxidase_C PF02913.19 GAM21212.1 - 7.8e-59 199.3 0.0 1.1e-58 198.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAM21212.1 - 2.6e-37 127.7 0.0 4.9e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain KH_8 PF17903.1 GAM21213.1 - 3.2e-06 27.1 0.0 1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 GAM21213.1 - 0.0013 18.5 0.5 0.0013 18.5 0.5 1.9 2 0 0 2 2 2 1 KH domain pKID PF02173.17 GAM21214.1 - 0.026 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 pKID domain Aminotran_5 PF00266.19 GAM21215.1 - 6e-41 140.6 0.0 9.5e-41 140.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAM21215.1 - 0.00021 20.0 0.0 0.00029 19.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAM21215.1 - 0.00067 19.1 0.0 0.0057 16.0 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family PALP PF00291.25 GAM21215.1 - 0.00071 19.1 0.0 0.0044 16.5 0.0 2.0 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Pyridoxal_deC PF00282.19 GAM21215.1 - 0.012 14.4 0.8 0.095 11.4 0.1 2.4 3 0 0 3 3 3 0 Pyridoxal-dependent decarboxylase conserved domain DUF3827 PF12877.7 GAM21217.1 - 0.021 13.2 3.3 0.031 12.6 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EGF PF00008.27 GAM21217.1 - 0.023 15.0 11.5 0.05 13.9 11.5 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 GAM21217.1 - 0.027 14.5 8.6 0.085 12.9 8.6 1.9 1 0 0 1 1 1 0 Tenascin EGF domain TIG PF01833.24 GAM21217.1 - 0.052 13.6 13.4 0.031 14.3 2.0 3.7 2 1 1 3 3 3 0 IPT/TIG domain EGF_2 PF07974.13 GAM21217.1 - 0.072 13.5 15.7 0.16 12.3 15.7 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 GAM21217.1 - 0.22 12.2 6.5 0.68 10.7 6.5 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF SKG6 PF08693.10 GAM21217.1 - 1.9 8.0 11.6 3.6 7.1 11.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF717 PF05338.12 GAM21218.1 - 0.027 14.6 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF717) AT_hook PF02178.19 GAM21218.1 - 0.7 10.0 6.0 1.7 8.8 6.0 1.7 1 0 0 1 1 1 0 AT hook motif APG12 PF04110.13 GAM21219.1 - 2.5e-28 98.3 0.1 3.7e-28 97.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 GAM21219.1 - 6.5e-07 29.5 0.0 8.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Auxin_repressed PF05564.12 GAM21219.1 - 0.0059 17.3 0.7 0.13 13.0 2.3 2.1 2 0 0 2 2 2 1 Dormancy/auxin associated protein Peptidase_C13 PF01650.18 GAM21219.1 - 0.054 13.0 0.1 0.16 11.5 0.0 1.7 1 1 1 2 2 2 0 Peptidase C13 family Thump_like PF18096.1 GAM21219.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 THUMP domain-like EF1G PF00647.19 GAM21220.1 - 2.2e-43 146.7 0.4 6.4e-43 145.2 0.1 1.9 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 GAM21220.1 - 1.3e-13 51.0 0.8 2.3e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM21220.1 - 2e-13 50.4 0.0 3.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM21220.1 - 3.2e-08 33.5 0.0 6.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM21220.1 - 3.9e-07 30.2 0.0 8.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM21220.1 - 6e-06 26.6 0.0 1.6e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM21220.1 - 2e-05 24.8 0.0 5.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAM21220.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_60s PF00428.19 GAM21220.1 - 0.18 12.4 7.5 0.45 11.1 7.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein BK_channel_a PF03493.18 GAM21221.1 - 1e-16 60.9 0.6 8.1e-16 58.0 0.1 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 GAM21221.1 - 2.2e-14 53.3 17.7 2.2e-14 53.3 17.7 1.9 3 0 0 3 3 3 1 Ion transport protein Ion_trans_2 PF07885.16 GAM21221.1 - 1.3e-10 41.1 2.9 1.3e-10 41.1 2.9 2.3 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 GAM21221.1 - 3.6e-07 30.4 0.0 0.031 14.5 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Pkinase PF00069.25 GAM21222.1 - 1.3e-75 254.2 0.0 1.7e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21222.1 - 1.1e-37 129.7 0.0 1.6e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 GAM21222.1 - 1.6e-10 41.1 0.0 3e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 GAM21222.1 - 7.9e-08 32.0 0.0 3.2e-07 29.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 GAM21222.1 - 1.4e-06 27.8 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM21222.1 - 0.0019 17.0 2.0 0.0066 15.3 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM21222.1 - 0.011 14.7 0.1 0.019 14.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RasGEF PF00617.19 GAM21223.1 - 7.2e-59 198.9 5.0 1.9e-58 197.6 3.3 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM21223.1 - 5.3e-24 84.5 2.0 2e-23 82.6 0.5 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif LisH_TPL PF17814.1 GAM21223.1 - 0.026 14.2 0.3 0.026 14.2 0.3 3.0 3 0 0 3 3 3 0 LisH-like dimerisation domain LisH PF08513.11 GAM21223.1 - 0.065 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 LisH Peptidase_C13 PF01650.18 GAM21224.1 - 6.2e-46 157.0 0.0 9.7e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 GAM21224.1 - 0.0075 16.5 0.2 0.025 14.8 0.0 1.9 2 0 0 2 2 2 1 Mid domain of argonaute DUF3989 PF13150.6 GAM21224.1 - 0.047 13.4 0.0 2.9 7.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Exo84_C PF16528.5 GAM21225.1 - 4.3e-34 118.1 6.5 4.9e-34 118.0 4.5 2.2 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 GAM21225.1 - 5e-05 23.3 4.3 6.6e-05 22.9 0.6 3.1 3 0 0 3 3 3 1 Vps51/Vps67 SSTK-IP PF15836.5 GAM21225.1 - 0.079 13.1 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Secretin_N_2 PF07655.13 GAM21225.1 - 0.95 10.1 10.2 2.6 8.6 10.2 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain CYTH PF01928.21 GAM21226.1 - 1.8e-13 50.8 0.1 2.7e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 CYTH domain DUF1412 PF07203.11 GAM21226.1 - 0.21 11.8 0.1 0.43 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) Metallophos PF00149.28 GAM21227.1 - 1.4e-08 35.5 0.2 2.7e-08 34.6 0.2 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM21227.1 - 0.0021 18.3 3.9 0.78 9.9 0.4 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Pox_A32 PF04665.12 GAM21227.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein HdeA PF06411.11 GAM21227.1 - 0.047 13.9 0.1 2 8.7 0.1 2.4 2 0 0 2 2 2 0 HdeA/HdeB family ABC_membrane PF00664.23 GAM21228.1 - 1.3e-73 248.0 34.0 1e-39 136.9 15.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM21228.1 - 1.6e-51 174.4 0.2 9.7e-30 103.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM21228.1 - 3.5e-09 36.4 7.1 0.011 15.1 1.3 4.4 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM21228.1 - 1.2e-06 28.1 0.3 0.036 13.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM21228.1 - 6.9e-06 26.5 0.0 0.13 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 GAM21228.1 - 9e-06 25.7 0.4 0.16 12.0 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM21228.1 - 2.8e-05 24.1 0.4 0.0086 16.0 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 GAM21228.1 - 6.8e-05 23.5 3.2 0.13 12.7 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 GAM21228.1 - 0.00013 21.9 1.1 0.16 11.8 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAM21228.1 - 0.0006 19.6 2.0 0.3 10.7 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF815 PF05673.13 GAM21228.1 - 0.00088 18.5 0.2 0.75 8.9 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAM21228.1 - 0.0013 19.0 0.4 0.54 10.5 0.1 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAM21228.1 - 0.0021 17.4 0.6 0.19 11.0 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin TrwB_AAD_bind PF10412.9 GAM21228.1 - 0.0027 16.7 0.1 0.36 9.7 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 GAM21228.1 - 0.0036 17.0 2.6 1.3 8.7 0.2 3.4 3 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 GAM21228.1 - 0.0066 16.0 0.3 0.92 9.0 0.2 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 GAM21228.1 - 0.011 14.8 0.0 4.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 GAM21228.1 - 0.012 15.7 0.5 0.14 12.2 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Roc PF08477.13 GAM21228.1 - 0.013 15.7 0.7 16 5.8 0.0 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 GAM21228.1 - 0.018 14.7 0.6 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 GAM21228.1 - 0.035 14.5 0.2 13 6.2 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Pex24p PF06398.11 GAM21228.1 - 0.1 11.6 2.5 0.29 10.1 2.5 1.7 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin FtsK_SpoIIIE PF01580.18 GAM21228.1 - 0.15 11.4 0.7 8.7 5.6 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF536 PF04394.14 GAM21228.1 - 0.17 11.8 0.7 0.43 10.5 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF536 Dynamin_N PF00350.23 GAM21228.1 - 0.25 11.4 9.4 0.071 13.2 0.3 2.9 3 0 0 3 3 3 0 Dynamin family Mit_KHE1 PF10173.9 GAM21228.1 - 1.6 8.8 4.3 3.9 7.5 4.3 1.6 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related OppC_N PF12911.7 GAM21228.1 - 1.9 8.6 5.8 9.4 6.3 5.8 2.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C S_4TM PF18159.1 GAM21228.1 - 8.1 5.7 11.4 0.65 9.2 0.7 2.7 2 1 1 3 3 3 0 SMODS-associating 4TM effector domain TLD PF07534.16 GAM21229.1 - 4.1e-37 127.5 0.2 1.7e-36 125.5 0.2 2.1 3 0 0 3 3 3 1 TLD RRM_1 PF00076.22 GAM21230.1 - 1.1e-29 102.0 0.4 1.1e-14 54.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM21230.1 - 2.6e-11 43.5 0.1 0.0004 20.4 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 GAM21230.1 - 0.0018 18.1 0.1 0.9 9.3 0.0 2.5 1 1 2 3 3 3 2 Rrp7 RRM-like N-terminal domain Laminin_G_2 PF02210.24 GAM21230.1 - 0.058 14.0 0.1 1.4 9.5 0.1 2.1 2 0 0 2 2 2 0 Laminin G domain UPF0242 PF06785.11 GAM21231.1 - 0.12 12.5 15.9 0.2 11.8 15.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Tropomyosin_1 PF12718.7 GAM21231.1 - 0.15 12.2 20.5 0.17 12.0 1.4 2.3 1 1 1 2 2 2 0 Tropomyosin like LMBR1 PF04791.16 GAM21231.1 - 0.15 10.9 1.8 0.15 10.9 1.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HAUS5 PF14817.6 GAM21231.1 - 0.2 10.4 10.7 0.25 10.0 10.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Exonuc_VII_L PF02601.15 GAM21231.1 - 0.53 9.8 7.3 0.77 9.3 7.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 GAM21231.1 - 2.3 7.5 20.9 0.19 11.0 15.9 1.7 2 1 0 2 2 2 0 FAM76 protein ATF7IP_BD PF16788.5 GAM21231.1 - 3.7 7.6 16.0 0.57 10.2 11.9 1.7 2 1 0 2 2 2 0 ATF-interacting protein binding domain SlyX PF04102.12 GAM21231.1 - 4.6 7.9 8.7 0.87 10.2 3.0 2.5 2 1 1 3 3 3 0 SlyX DUF641 PF04859.12 GAM21231.1 - 5.2 7.4 10.1 2.1 8.7 6.7 1.9 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) GREB1 PF15782.5 GAM21231.1 - 5.3 4.0 11.8 6.8 3.7 11.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FlaC_arch PF05377.11 GAM21231.1 - 6.1 7.3 10.1 54 4.3 1.5 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF5320 PF17253.2 GAM21231.1 - 7 7.8 7.0 5.2 8.2 0.2 2.7 3 0 0 3 3 2 0 Family of unknown function (DUF5320) FNIP PF05725.12 GAM21233.1 - 4.9e-31 106.6 13.0 8e-11 41.9 0.0 4.6 2 1 3 6 6 6 5 FNIP Repeat F-box PF00646.33 GAM21233.1 - 0.0063 16.4 0.4 0.023 14.6 0.4 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAM21233.1 - 0.092 12.6 0.5 0.24 11.3 0.4 1.7 1 1 0 1 1 1 0 F-box Acyl_CoA_thio PF02551.15 GAM21234.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA thioesterase RIFIN PF02009.16 GAM21235.1 - 0.8 9.5 2.3 1.4 8.7 2.3 1.4 1 0 0 1 1 1 0 Rifin Peptidase_S28 PF05577.12 GAM21236.1 - 5.8e-80 269.2 6.6 1.5e-79 267.8 6.6 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 zf-CCHC_3 PF13917.6 GAM21237.1 - 6.8e-06 26.0 0.6 6.8e-06 26.0 0.6 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 GAM21237.1 - 0.004 17.2 1.7 0.0062 16.6 1.7 1.3 1 0 0 1 1 1 1 Zinc knuckle SprA-related PF12118.8 GAM21237.1 - 0.0089 15.2 10.2 0.0097 15.1 10.2 1.0 1 0 0 1 1 1 1 SprA-related family DUF2828 PF11443.8 GAM21237.1 - 0.14 10.2 13.3 0.14 10.2 13.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RNA_polI_A34 PF08208.11 GAM21237.1 - 0.29 11.2 35.7 0.43 10.6 35.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YL1 PF05764.13 GAM21237.1 - 0.56 10.3 33.7 0.7 10.0 33.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein AAA_11 PF13086.6 GAM21237.1 - 0.66 9.7 10.5 0.66 9.7 10.5 1.2 1 0 0 1 1 1 0 AAA domain Connexin PF00029.19 GAM21237.1 - 0.86 9.3 10.2 1.1 9.0 10.2 1.3 1 0 0 1 1 1 0 Connexin RR_TM4-6 PF06459.12 GAM21237.1 - 1.5 8.6 18.0 1.7 8.4 18.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 GAM21237.1 - 5 5.3 32.0 5.6 5.1 32.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GAM21237.1 - 5.1 5.7 15.5 5.7 5.6 15.5 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 GAM21237.1 - 5.2 7.0 5.7 5.4 7.0 5.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region An_peroxidase PF03098.15 GAM21238.1 - 1.3e-127 426.7 0.0 1.5e-127 426.4 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Tra_M PF05261.11 GAM21240.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.5 2 0 0 2 2 2 0 TraM protein, DNA-binding DUF5383 PF17355.2 GAM21241.1 - 0.63 10.4 5.7 0.37 11.2 0.7 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Ferlin_C PF16165.5 GAM21241.1 - 3 7.8 5.2 2.5 8.1 2.0 2.2 2 0 0 2 2 2 0 Ferlin C-terminus PBP1_TM PF14812.6 GAM21241.1 - 10 6.6 12.6 0.26 11.7 3.5 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SPRY PF00622.28 GAM21242.1 - 3.7e-10 40.0 0.2 6.3e-10 39.2 0.2 1.4 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 GAM21242.1 - 3.4e-05 23.6 0.1 6.6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM21242.1 - 0.018 14.9 0.2 0.018 14.9 0.2 1.9 2 0 0 2 2 2 0 F-box domain DUF1843 PF08898.10 GAM21242.1 - 0.14 12.7 1.3 0.5 10.9 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Med4 PF10018.9 GAM21242.1 - 0.14 11.8 2.7 5.3 6.7 0.3 2.5 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Occludin_ELL PF07303.13 GAM21242.1 - 0.17 12.7 0.1 0.17 12.7 0.1 4.0 4 0 0 4 4 4 0 Occludin homology domain Det1 PF09737.9 GAM21243.1 - 2.1e-111 372.9 9.7 2.1e-81 274.1 4.9 2.7 3 0 0 3 3 3 2 De-etiolated protein 1 Det1 Mucin PF01456.17 GAM21243.1 - 0.0046 17.0 21.0 0.0046 17.0 21.0 4.3 4 1 0 4 4 4 1 Mucin-like glycoprotein Homeodomain PF00046.29 GAM21244.1 - 5.3e-18 64.6 12.4 5.5e-09 35.8 0.8 3.5 3 0 0 3 3 3 2 Homeodomain Homeobox_KN PF05920.11 GAM21244.1 - 1.3e-06 28.2 2.1 0.065 13.2 0.1 3.8 3 0 0 3 3 3 2 Homeobox KN domain HTH_17 PF12728.7 GAM21244.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 GAM21244.1 - 0.02 14.5 0.4 3.2 7.5 0.1 2.6 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Phage_terminase PF10668.9 GAM21244.1 - 0.068 13.2 0.1 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Phage terminase small subunit SSP160 PF06933.11 GAM21244.1 - 2.5 6.2 15.3 3.8 5.6 15.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Arm PF00514.23 GAM21245.1 - 0.13 12.3 0.0 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Period_C PF12114.8 GAM21245.1 - 1.1 8.8 8.4 3 7.4 8.4 1.7 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Pkinase PF00069.25 GAM21246.1 - 5.2e-63 212.9 0.1 8.4e-63 212.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21246.1 - 3.9e-46 157.4 0.1 6.1e-46 156.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM21246.1 - 0.00023 20.1 0.1 0.00043 19.2 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAM21246.1 - 0.00071 19.6 0.1 0.0042 17.0 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM21246.1 - 0.0083 15.7 0.3 0.016 14.8 0.3 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 GAM21246.1 - 0.011 15.1 0.2 0.019 14.3 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM21246.1 - 0.024 14.0 0.0 0.05 12.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 GAM21246.1 - 0.063 12.2 0.1 0.11 11.4 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DUF1235 PF06822.12 GAM21247.1 - 0.094 12.0 0.7 0.12 11.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) FNIP PF05725.12 GAM21248.1 - 7.9e-14 51.5 9.5 1.3e-05 25.3 3.4 3.8 3 1 1 4 4 4 4 FNIP Repeat LRR_4 PF12799.7 GAM21248.1 - 0.0093 16.4 3.3 0.17 12.4 0.2 3.1 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) FNIP PF05725.12 GAM21249.1 - 1.8e-12 47.2 1.0 0.00026 21.1 0.1 4.0 2 1 2 4 4 4 4 FNIP Repeat GST_N_3 PF13417.6 GAM21250.1 - 2.3e-12 47.1 0.0 1e-11 45.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM21250.1 - 6e-11 42.4 0.1 1.6e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM21250.1 - 6.6e-11 42.4 0.1 3.2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM21250.1 - 4.9e-10 39.3 0.1 2.1e-09 37.3 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM21250.1 - 1.1e-09 38.5 0.0 3.1e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM21250.1 - 3.4e-08 33.6 0.1 6.1e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Usg PF06233.12 GAM21250.1 - 0.015 15.4 0.2 0.035 14.3 0.2 1.6 1 0 0 1 1 1 0 Usg-like family Glutaredoxin2_C PF04399.13 GAM21250.1 - 0.028 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain FNIP PF05725.12 GAM21251.1 - 6.2e-12 45.5 6.8 1.1e-05 25.5 0.2 3.4 2 1 0 2 2 2 2 FNIP Repeat Ion_trans PF00520.31 GAM21252.1 - 5.3e-07 29.1 4.8 6.9e-07 28.7 4.8 1.1 1 0 0 1 1 1 1 Ion transport protein PGA2 PF07543.12 GAM21252.1 - 2.1 8.3 9.1 0.037 14.0 1.8 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 CDC45 PF02724.14 GAM21252.1 - 2.6 6.2 10.1 4.4 5.5 9.4 1.6 1 1 1 2 2 2 0 CDC45-like protein ANAPC15 PF15243.6 GAM21252.1 - 3.5 8.1 7.7 0.53 10.7 3.9 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 SR-25 PF10500.9 GAM21252.1 - 9.9 5.7 18.1 0.24 11.0 7.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein O-antigen_lig PF13425.6 GAM21253.1 - 0.0058 15.5 1.8 0.0073 15.2 1.8 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein FAM176 PF14851.6 GAM21253.1 - 0.028 14.1 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Paralemmin PF03285.15 GAM21253.1 - 0.24 10.9 4.0 0.28 10.7 4.0 1.3 1 1 0 1 1 1 0 Paralemmin PhoLip_ATPase_C PF16212.5 GAM21255.1 - 1.4e-71 241.2 29.9 1.4e-71 241.2 29.9 3.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM21255.1 - 1.8e-19 69.2 1.3 7.8e-19 67.1 1.3 2.2 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAM21255.1 - 6.3e-16 58.2 0.1 4.6e-14 52.3 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM21255.1 - 3.1e-12 47.2 0.0 6.1e-07 29.9 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAM21255.1 - 4.4e-09 36.1 1.9 7.5e-08 32.1 0.0 3.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAM21255.1 - 0.00019 21.3 0.5 0.0037 17.0 0.5 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAM21255.1 - 0.0034 17.8 0.0 0.94 9.8 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PI3K_1B_p101 PF10486.9 GAM21255.1 - 0.24 9.1 5.6 2.5 5.8 0.7 2.1 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ABC_membrane PF00664.23 GAM21257.1 - 5.3e-74 249.3 31.5 1e-42 146.7 13.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM21257.1 - 8.2e-52 175.4 0.1 1.1e-29 103.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM21257.1 - 4.2e-09 36.2 6.9 0.012 15.1 0.4 4.3 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM21257.1 - 1.8e-07 30.8 0.3 0.0055 16.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAM21257.1 - 5.6e-06 26.4 0.4 0.16 12.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM21257.1 - 8.7e-06 26.2 0.1 0.081 13.3 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM21257.1 - 1.5e-05 24.9 0.3 0.01 15.8 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 GAM21257.1 - 4e-05 23.5 0.0 0.14 11.9 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAM21257.1 - 8e-05 22.6 0.2 0.16 11.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAM21257.1 - 0.00011 22.8 5.5 0.25 11.8 2.6 3.3 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.13 GAM21257.1 - 0.00038 19.7 0.6 0.73 9.0 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_30 PF13604.6 GAM21257.1 - 0.00047 19.9 1.7 0.63 9.7 0.1 3.7 3 1 0 4 4 4 1 AAA domain AAA_22 PF13401.6 GAM21257.1 - 0.00088 19.6 0.3 0.43 10.9 0.1 3.1 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 GAM21257.1 - 0.0014 18.7 1.7 0.056 13.5 0.1 2.6 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.12 GAM21257.1 - 0.0014 17.9 0.6 0.099 11.9 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 GAM21257.1 - 0.003 16.7 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 GAM21257.1 - 0.0063 16.1 2.2 0.6 9.6 0.1 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region Roc PF08477.13 GAM21257.1 - 0.0082 16.4 1.0 15 5.8 0.0 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 GAM21257.1 - 0.013 14.4 1.1 1.1 8.1 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 GAM21257.1 - 0.014 15.0 0.6 0.11 12.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain S_4TM PF18159.1 GAM21257.1 - 0.053 12.8 3.9 2.9 7.1 0.6 2.4 1 1 1 2 2 2 0 SMODS-associating 4TM effector domain DUF87 PF01935.17 GAM21257.1 - 0.064 13.3 2.5 0.17 11.9 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA PF00004.29 GAM21257.1 - 0.083 13.3 0.5 15 6.0 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Pex24p PF06398.11 GAM21257.1 - 0.089 11.8 3.8 0.18 10.7 3.8 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin FtsK_SpoIIIE PF01580.18 GAM21257.1 - 0.14 11.5 0.2 16 4.8 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family 4HBT_2 PF13279.6 GAM21258.1 - 7.7e-05 23.2 0.0 8.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily UBA_6 PF18039.1 GAM21258.1 - 0.18 11.8 0.0 1.1 9.3 0.0 2.2 3 0 0 3 3 3 0 UBA-like domain DDE_Tnp_4 PF13359.6 GAM21259.1 - 2.5e-22 79.3 0.4 1e-20 74.0 0.3 3.0 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM21259.1 - 2.3e-07 30.7 1.0 2.3e-07 30.7 1.0 2.0 2 0 0 2 2 2 1 Transposase DDE domain CCDC53 PF10152.9 GAM21259.1 - 0.011 16.1 14.1 0.018 15.5 0.1 2.8 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex TFIIA PF03153.13 GAM21259.1 - 1.9 8.4 24.1 0.038 14.0 14.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1018 PF06252.12 GAM21259.1 - 3.2 8.8 6.9 47 5.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) Roughex PF06020.11 GAM21259.1 - 4.3 6.4 8.9 0.093 11.8 2.1 1.6 2 0 0 2 2 2 0 Drosophila roughex protein Spt20 PF12090.8 GAM21259.1 - 9.4 5.8 30.9 0.37 10.4 19.3 2.2 2 0 0 2 2 2 0 Spt20 family DUF1084 PF06454.11 GAM21260.1 - 6.3e-07 29.1 29.1 3.6e-06 26.6 29.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) FAA_hydrolase PF01557.18 GAM21261.1 - 1e-66 224.7 0.0 1.6e-66 224.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HMG_box PF00505.19 GAM21262.1 - 1.4e-16 60.7 1.6 1.4e-16 60.7 1.6 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAM21262.1 - 4.4e-12 46.4 0.8 4.4e-12 46.4 0.8 2.0 2 1 0 2 2 2 1 HMG-box domain YABBY PF04690.13 GAM21262.1 - 2.9e-05 24.7 5.0 2.9e-05 24.7 5.0 1.4 1 1 0 1 1 1 1 YABBY protein SR-25 PF10500.9 GAM21262.1 - 0.0067 16.1 20.9 0.0067 16.1 20.9 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4770 PF15994.5 GAM21262.1 - 5 7.3 16.6 5.9 7.1 15.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4770) LIM PF00412.22 GAM21263.1 - 5.9e-38 128.9 52.0 3.9e-12 46.2 6.7 4.5 4 0 0 4 4 4 4 LIM domain RRM_1 PF00076.22 GAM21264.1 - 2.1e-37 126.8 0.3 2.1e-19 69.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM21264.1 - 8.6e-07 28.6 0.0 1.8e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM21264.1 - 0.0093 15.8 0.1 1 9.2 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif DbpA PF03880.15 GAM21264.1 - 0.062 13.3 0.3 0.4 10.7 0.0 2.2 2 1 0 2 2 2 0 DbpA RNA binding domain OB_RNB PF08206.11 GAM21264.1 - 0.17 11.6 0.0 24 4.7 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain CSD PF00313.22 GAM21264.1 - 0.18 11.7 0.5 1.6 8.6 0.2 2.2 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain SKA1 PF07160.12 GAM21265.1 - 0.0044 16.9 4.0 0.0052 16.7 4.0 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF4498 PF14926.6 GAM21265.1 - 0.03 13.6 1.3 0.034 13.5 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) EAP30 PF04157.16 GAM21265.1 - 0.12 11.6 1.5 0.16 11.2 1.5 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family zf-C4H2 PF10146.9 GAM21265.1 - 0.32 11.3 5.2 0.4 10.9 5.0 1.2 1 1 0 1 1 1 0 Zinc finger-containing protein UPF0020 PF01170.18 GAM21266.1 - 6.7e-18 65.1 0.2 1.4e-12 47.7 0.0 2.8 3 0 0 3 3 3 2 Putative RNA methylase family UPF0020 AviRa PF11599.8 GAM21266.1 - 0.01 15.3 1.2 6.5 6.1 0.0 3.7 3 1 1 4 4 4 0 RRNA methyltransferase AviRa N6_N4_Mtase PF01555.18 GAM21266.1 - 0.02 14.6 0.0 0.057 13.1 0.0 1.7 2 0 0 2 2 2 0 DNA methylase SUIM_assoc PF16619.5 GAM21266.1 - 1.1 9.3 8.2 2.9 8.0 8.2 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Androgen_recep PF02166.16 GAM21266.1 - 9.2 5.0 7.0 14 4.3 7.0 1.2 1 0 0 1 1 1 0 Androgen receptor FNIP PF05725.12 GAM21267.1 - 3.5e-51 171.1 0.2 1.3e-11 44.4 0.1 8.2 5 2 3 8 8 8 7 FNIP Repeat LRR_8 PF13855.6 GAM21267.1 - 0.0022 17.7 0.8 0.11 12.3 0.2 3.7 3 1 0 3 3 3 1 Leucine rich repeat DUF1769 PF08588.10 GAM21267.1 - 0.024 14.9 0.6 23 5.3 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1769) Robl_LC7 PF03259.17 GAM21268.1 - 0.005 16.6 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 Roadblock/LC7 domain dCache_1 PF02743.18 GAM21268.1 - 0.037 13.8 0.1 0.068 13.0 0.0 1.5 2 0 0 2 2 2 0 Cache domain PPR_2 PF13041.6 GAM21269.1 - 0.016 15.4 0.4 26 5.1 0.0 4.2 3 0 0 3 3 3 0 PPR repeat family SPT16 PF08644.11 GAM21269.1 - 0.042 14.0 1.3 0.11 12.7 1.3 1.6 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DnaB PF00772.21 GAM21269.1 - 0.29 11.2 2.8 1.7 8.8 0.2 3.4 3 1 0 3 3 3 0 DnaB-like helicase N terminal domain TFIIF_beta PF02270.15 GAM21270.1 - 2.4e-22 78.8 0.5 4.2e-22 78.1 0.5 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 GAM21270.1 - 3e-08 34.5 1.5 1e-07 32.7 1.4 2.1 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 GAM21270.1 - 0.00012 22.9 0.9 0.00019 22.2 0.9 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain GN3L_Grn1 PF08701.11 GAM21271.1 - 4.8e-21 74.6 16.1 4.8e-21 74.6 16.1 4.1 4 1 1 5 5 5 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 GAM21271.1 - 4.5e-16 59.0 1.5 3.6e-14 52.8 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM21271.1 - 3.1e-09 36.6 0.1 2.1e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAM21271.1 - 0.0011 18.5 1.1 0.12 11.9 0.0 3.5 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM21271.1 - 0.0012 18.8 7.4 0.0089 15.9 0.1 3.1 3 1 1 4 4 4 2 RsgA GTPase AAA_16 PF13191.6 GAM21271.1 - 0.007 16.8 2.3 0.035 14.5 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 GAM21271.1 - 0.33 11.5 0.0 0.33 11.5 0.0 3.6 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 GAM21271.1 - 0.96 10.0 0.0 0.96 10.0 0.0 2.9 3 1 0 3 3 3 0 ABC transporter UPF0767 PF15990.5 GAM21271.1 - 3.4 7.9 0.0 3.4 7.9 0.0 3.3 3 0 0 3 3 3 0 UPF0767 family ACOX PF01756.19 GAM21272.1 - 7e-32 110.4 0.1 1.3e-31 109.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 GAM21272.1 - 2.8e-21 75.5 0.0 5.5e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAM21272.1 - 3.4e-05 24.1 0.4 0.00023 21.4 0.4 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 GAM21273.1 - 3.5e-30 104.9 0.1 7.7e-30 103.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 GAM21273.1 - 9.1e-20 70.7 0.0 1.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAM21273.1 - 5.3e-06 26.7 0.0 1.3e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CBM49 PF09478.10 GAM21274.1 - 7e-07 29.5 0.1 1.3e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 SpoIIIAH PF12685.7 GAM21274.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein PT PF04886.12 GAM21274.1 - 0.5 10.0 20.5 0.15 11.6 1.3 3.9 1 1 1 2 2 2 0 PT repeat Lactamase_B_2 PF12706.7 GAM21275.1 - 1e-39 136.1 0.4 2.3e-39 135.0 0.4 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM21275.1 - 1.2e-17 64.3 0.0 2.1e-17 63.5 0.0 1.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain AMP-binding PF00501.28 GAM21276.1 - 9.4e-111 370.4 0.0 1.2e-110 370.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM21276.1 - 0.0025 18.8 0.0 0.006 17.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SH3_1 PF00018.28 GAM21276.1 - 0.083 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 SH3 domain RhoGAP PF00620.27 GAM21277.1 - 1.2e-19 70.7 0.0 4.8e-19 68.7 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain Myc_N PF01056.18 GAM21277.1 - 0.19 11.6 20.6 1.1 9.1 0.6 2.5 2 1 0 2 2 2 0 Myc amino-terminal region BSP_II PF05432.11 GAM21277.1 - 2.6 7.6 19.7 0.7 9.5 2.9 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) GST_N_2 PF13409.6 GAM21278.1 - 3.8e-23 81.6 0.0 1.4e-22 79.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM21278.1 - 2.1e-14 53.3 0.0 4.1e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM21278.1 - 3.5e-09 36.8 0.1 6.6e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM21278.1 - 5.9e-08 32.8 0.1 1.5e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM21278.1 - 0.00027 21.3 0.0 0.0044 17.4 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAM21278.1 - 0.00047 19.9 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain P4Ha_N PF08336.11 GAM21278.1 - 0.19 11.7 1.4 0.96 9.5 0.3 2.2 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SdrD_B PF17210.3 GAM21279.1 - 7.8e-24 84.1 14.9 1.8e-15 57.2 0.6 11.8 8 2 6 14 14 14 7 SdrD B-like domain DUF3248 PF11609.8 GAM21279.1 - 0.00013 21.8 0.0 18 5.4 0.0 5.2 5 0 0 5 5 5 1 Protein of unknown function (DUF3248) TcfC PF16967.5 GAM21279.1 - 0.0003 20.2 0.9 46 3.6 0.0 5.3 5 0 0 5 5 5 0 E-set like domain ATP-grasp_3 PF02655.14 GAM21279.1 - 0.00082 19.4 0.2 47 4.0 0.0 5.5 6 0 0 6 6 6 0 ATP-grasp domain Corona_NS2 PF04753.12 GAM21279.1 - 0.11 13.0 0.4 32 5.2 0.0 4.4 5 0 0 5 5 5 0 Coronavirus non-structural protein NS2 Peptidase_C48 PF02902.19 GAM21280.1 - 8.5e-31 107.5 1.8 6.8e-30 104.5 1.8 2.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Aldedh PF00171.22 GAM21281.1 - 9.1e-82 275.0 0.0 1.1e-81 274.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fib_alpha PF08702.10 GAM21281.1 - 0.095 12.9 0.6 0.77 9.9 0.8 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Metallophos PF00149.28 GAM21282.1 - 6.7e-17 62.7 0.2 1e-16 62.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 GAM21282.1 - 2.8e-08 34.5 0.2 9.3e-08 32.8 0.2 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 GAM21282.1 - 1.4e-05 25.6 0.1 3.3e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 GAM21282.1 - 0.00036 20.8 0.0 0.0023 18.1 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Methuselah_N PF06652.12 GAM21282.1 - 0.12 12.2 0.2 0.24 11.3 0.2 1.4 1 0 0 1 1 1 0 Methuselah N-terminus RhoGEF PF00621.20 GAM21283.1 - 9.1e-42 143.3 7.4 9.1e-42 143.3 7.4 1.9 2 0 0 2 2 2 1 RhoGEF domain PH_13 PF16652.5 GAM21283.1 - 0.025 14.4 1.6 0.081 12.7 0.1 2.5 1 1 1 2 2 2 0 Pleckstrin homology domain DZR PF12773.7 GAM21283.1 - 0.095 12.7 16.1 0.2 11.7 16.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 GAM21283.1 - 0.2 11.1 4.2 0.55 9.7 4.2 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 GAM21283.1 - 0.31 10.8 5.0 0.75 9.6 5.0 1.7 1 0 0 1 1 1 0 zinc-ribbon domain RhoGAP PF00620.27 GAM21285.1 - 4.7e-30 104.4 0.0 1.4e-29 102.9 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain RPEL PF02755.15 GAM21285.1 - 0.005 16.5 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 RPEL repeat Hamartin PF04388.12 GAM21285.1 - 7.4 5.1 13.5 0.13 10.9 6.2 1.7 2 0 0 2 2 2 0 Hamartin protein SIR2 PF02146.17 GAM21286.1 - 3.1e-49 167.3 0.0 4.7e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 GAM21286.1 - 6.6e-05 22.7 0.0 0.00018 21.2 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain zf-RING_9 PF13901.6 GAM21287.1 - 2.7e-60 203.9 12.5 3.1e-60 203.7 10.6 2.1 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon RUN PF02759.19 GAM21287.1 - 3.2e-12 46.5 0.1 9.4e-12 45.0 0.1 1.8 1 0 0 1 1 1 1 RUN domain Spt4 PF06093.13 GAM21287.1 - 0.1 12.7 4.5 0.41 10.8 4.5 2.1 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger PHD_4 PF16866.5 GAM21287.1 - 2 8.5 8.7 10 6.3 8.7 2.3 1 0 0 1 1 1 0 PHD-finger Ribosomal_L39 PF00832.20 GAM21288.1 - 7.8e-23 79.8 10.6 9e-23 79.6 10.6 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Yae1_N PF09811.9 GAM21289.1 - 5e-08 32.5 0.1 6.9e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Clp1 PF06807.14 GAM21289.1 - 0.036 14.5 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 DUF4685 PF15737.5 GAM21289.1 - 0.076 13.5 0.9 0.15 12.5 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) Tetraspanin PF00335.20 GAM21289.1 - 2.8 7.6 13.8 15 5.2 13.8 1.9 1 1 0 1 1 1 0 Tetraspanin family RCC1 PF00415.18 GAM21290.1 - 1.1e-35 122.0 12.7 1.9e-14 54.0 0.0 5.3 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM21290.1 - 5.8e-22 77.0 17.1 3.9e-08 32.9 0.2 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat KIX_2 PF16987.5 GAM21291.1 - 8.8e-05 22.4 0.2 0.00049 20.0 0.2 2.4 1 0 0 1 1 1 1 KIX domain Acyl-CoA_dh_C PF12806.7 GAM21291.1 - 0.0075 16.4 0.3 2.7 8.2 0.2 2.4 2 0 0 2 2 2 2 Acetyl-CoA dehydrogenase C-terminal like Cyt_b-c1_8 PF10890.8 GAM21291.1 - 0.14 12.6 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 CDT1_C PF16679.5 GAM21291.1 - 0.14 12.6 0.1 0.14 12.6 0.1 2.7 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain YqeY PF09424.10 GAM21291.1 - 0.18 11.9 2.1 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Yqey-like protein DnaB_bind PF10410.9 GAM21291.1 - 0.19 11.9 0.6 1.7 8.9 0.1 2.5 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase 60KD_IMP PF02096.20 GAM21292.1 - 1.5e-21 77.0 3.5 2.1e-21 76.6 3.5 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Tli4_N PF18443.1 GAM21293.1 - 0.04 14.3 0.7 0.11 12.9 0.7 1.7 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Lin-8 PF03353.15 GAM21293.1 - 1.6 8.3 24.5 1.8 8.0 10.7 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist VIT1 PF01988.19 GAM21293.1 - 3.2 7.6 6.9 0.49 10.2 2.1 1.9 2 0 0 2 2 2 0 VIT family FAM76 PF16046.5 GAM21293.1 - 4.5 6.5 21.2 0.63 9.3 9.4 2.3 2 0 0 2 2 2 0 FAM76 protein MAPEG PF01124.18 GAM21294.1 - 2.5e-23 82.4 0.7 2.9e-23 82.2 0.7 1.1 1 0 0 1 1 1 1 MAPEG family zf-NF-X1 PF01422.17 GAM21295.1 - 5.5e-12 45.5 87.6 2.8e-05 24.1 15.9 14.9 14 1 1 15 15 15 8 NF-X1 type zinc finger NCBP3 PF10309.9 GAM21295.1 - 0.043 13.7 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 SdrD_B PF17210.3 GAM21296.1 - 3.4e-15 56.3 5.7 4.9e-08 33.2 0.1 5.5 4 2 1 5 5 5 3 SdrD B-like domain Hamartin PF04388.12 GAM21296.1 - 2 7.0 12.4 2.6 6.6 12.4 1.2 1 0 0 1 1 1 0 Hamartin protein DNA_pol_phi PF04931.13 GAM21296.1 - 4.3 5.3 5.6 6.1 4.8 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_4 PF02390.17 GAM21297.1 - 6.8e-48 162.4 0.0 1.1e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 GAM21297.1 - 0.0043 16.9 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 GAM21297.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 GAM21297.1 - 0.0096 15.9 0.8 0.013 15.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM21297.1 - 0.012 16.3 0.0 0.026 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAM21297.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 GAM21297.1 - 0.12 13.0 0.0 1.1 9.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain eIF-6 PF01912.18 GAM21298.1 - 3.9e-76 254.8 0.6 8.4e-76 253.8 0.3 1.5 1 1 1 2 2 2 1 eIF-6 family Sec63 PF02889.16 GAM21299.1 - 3.3e-166 550.8 1.9 3.6e-86 288.5 0.2 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GAM21299.1 - 3.8e-44 150.5 1.1 1.4e-23 83.5 0.3 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 GAM21299.1 - 3e-34 117.5 0.5 3e-34 117.5 0.5 2.8 3 0 0 3 3 3 1 N-terminal helicase PWI domain ResIII PF04851.15 GAM21299.1 - 3.1e-23 82.6 0.1 3e-12 46.9 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM21299.1 - 1.8e-14 54.0 0.0 3.8e-06 27.2 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 GAM21299.1 - 0.00011 22.0 0.0 0.042 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain SWI2_SNF2 PF18766.1 GAM21299.1 - 0.002 17.8 1.2 0.15 11.7 0.0 2.8 3 0 0 3 3 3 1 SWI2/SNF2 ATPase T2SSE PF00437.20 GAM21299.1 - 0.029 13.4 0.0 3.4 6.6 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 GAM21299.1 - 0.092 12.2 0.0 0.57 9.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein T4BSS_DotI_IcmL PF11393.8 GAM21299.1 - 0.11 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component Proho_convert PF12177.8 GAM21299.1 - 0.15 12.1 0.3 15 5.7 0.1 2.7 2 0 0 2 2 2 0 Prohormone convertase enzyme ADH_zinc_N PF00107.26 GAM21300.1 - 2e-15 56.9 0.0 4.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM21300.1 - 4.8e-07 29.6 0.1 1.1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain UNC45-central PF11701.8 GAM21301.1 - 0.022 14.7 0.5 1.1 9.2 0.0 3.2 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central RTTN_N PF14726.6 GAM21301.1 - 0.19 12.5 2.8 84 4.1 0.0 4.8 5 0 0 5 5 5 0 Rotatin, an armadillo repeat protein, centriole functioning IMUP PF15761.5 GAM21302.1 - 5.2 7.8 16.9 7 7.4 16.9 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein SMC_N PF02463.19 GAM21303.1 - 1.5e-60 204.4 58.6 2e-31 109.1 23.1 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAM21303.1 - 7.5e-27 94.0 0.0 3.3e-26 91.9 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAM21303.1 - 2.2e-13 50.7 1.1 2.3e-06 27.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAM21303.1 - 3.6e-11 43.4 12.3 3.6e-11 43.4 12.3 6.1 3 2 2 6 6 6 1 AAA ATPase domain AAA_23 PF13476.6 GAM21303.1 - 5e-11 43.5 16.4 5e-11 43.5 16.4 8.4 3 2 2 5 5 5 1 AAA domain AAA_29 PF13555.6 GAM21303.1 - 1.9e-06 27.5 0.0 4.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 GAM21303.1 - 0.0047 17.4 0.0 0.0047 17.4 0.0 7.0 4 2 0 4 4 4 1 ABC transporter SbcCD_C PF13558.6 GAM21303.1 - 0.18 12.1 1.3 2.8 8.2 0.0 3.2 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 GAM21303.1 - 2.2 8.6 6.9 11 6.4 0.0 4.2 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 GAM21303.1 - 2.6 8.3 11.4 7 6.9 0.0 5.0 5 0 0 5 5 5 0 AAA domain RhoGEF PF00621.20 GAM21304.1 - 2.9e-50 171.0 1.0 4.5e-50 170.4 0.6 1.5 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 GAM21304.1 - 4.4e-20 71.6 6.9 4.4e-20 71.6 6.9 1.9 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 GAM21304.1 - 0.00062 20.2 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 GAM21304.1 - 0.011 16.0 4.7 0.011 16.0 4.7 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger IBR PF01485.21 GAM21304.1 - 0.031 14.5 4.2 0.11 12.7 4.2 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf_C2HC_14 PF18574.1 GAM21304.1 - 0.032 14.0 2.6 0.11 12.4 2.6 1.9 1 0 0 1 1 1 0 C2HC Zing finger domain PEP-utilisers_N PF05524.13 GAM21304.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal zf-ribbon_3 PF13248.6 GAM21304.1 - 0.14 11.6 0.1 0.14 11.6 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 GAM21304.1 - 1 9.5 9.9 49 4.0 9.9 2.7 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.6 GAM21304.1 - 1.3 9.0 6.8 3.3 7.6 6.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Dicty_REP PF05086.12 GAM21304.1 - 1.7 6.5 4.3 2.7 5.9 4.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-B_box PF00643.24 GAM21304.1 - 8.8 6.6 10.6 3.2 8.0 7.3 2.0 2 0 0 2 2 2 0 B-box zinc finger TAP_C PF03943.13 GAM21305.1 - 8.2e-13 47.8 0.2 1.5e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 GAM21305.1 - 3.1e-09 37.5 0.2 8.9e-09 35.9 0.2 1.7 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain UBA_4 PF14555.6 GAM21305.1 - 4.8e-07 29.5 0.1 1e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain LRR_9 PF14580.6 GAM21305.1 - 2.3e-05 24.0 0.0 4.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat CH PF00307.31 GAM21307.1 - 2.9e-17 62.8 0.0 7.8e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain RA PF00788.23 GAM21307.1 - 3.1e-12 46.9 0.0 0.00016 22.3 0.0 2.8 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain PH PF00169.29 GAM21307.1 - 2.3e-06 28.0 0.0 6.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 PH domain Ras_bdg_2 PF14847.6 GAM21307.1 - 0.1 12.9 0.1 4.1 7.8 0.1 2.9 2 0 0 2 2 2 0 Ras-binding domain of Byr2 DUF572 PF04502.13 GAM21307.1 - 0.27 10.8 20.8 0.47 10.0 20.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) polyprenyl_synt PF00348.17 GAM21308.1 - 6.3e-64 215.5 0.0 7.6e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RINT1_TIP1 PF04437.13 GAM21308.1 - 0.02 13.8 0.0 0.036 13.0 0.0 1.4 1 0 0 1 1 1 0 RINT-1 / TIP-1 family YoeB_toxin PF06769.14 GAM21308.1 - 0.032 14.3 0.8 2.4 8.2 0.0 2.8 3 0 0 3 3 3 0 YoeB-like toxin of bacterial type II toxin-antitoxin system FAA_hydrolase PF01557.18 GAM21309.1 - 1.9e-67 227.2 0.0 2.4e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SR-25 PF10500.9 GAM21310.1 - 0.05 13.2 17.0 0.053 13.1 17.0 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 GAM21310.1 - 0.064 13.9 17.0 0.091 13.5 17.0 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein CCDC106 PF15794.5 GAM21310.1 - 2 8.1 10.4 2.2 7.9 10.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 AF-4 PF05110.13 GAM21310.1 - 3.1 5.7 14.3 3.4 5.6 14.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein COMM_domain PF07258.14 GAM21311.1 - 9.4e-15 54.5 0.3 1e-14 54.4 0.3 1.0 1 0 0 1 1 1 1 COMM domain Amidohydro_2 PF04909.14 GAM21312.1 - 3.9e-23 82.7 0.0 4.9e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase RRM_1 PF00076.22 GAM21313.1 - 1.3e-15 56.9 0.0 2.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM21313.1 - 0.03 14.2 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 GAM21313.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif TFIIA PF03153.13 GAM21314.1 - 0.0016 18.5 17.0 0.002 18.2 17.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Rrp15p PF07890.12 GAM21314.1 - 0.039 14.3 9.8 0.42 11.0 2.9 2.6 2 0 0 2 2 2 0 Rrp15p Mitofilin PF09731.9 GAM21314.1 - 0.096 11.5 13.1 0.13 11.0 13.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CPSF100_C PF13299.6 GAM21314.1 - 0.58 10.3 13.2 0.27 11.4 2.9 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 GAM21314.1 - 2 9.1 18.6 0.96 10.1 10.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Thg1C PF14413.6 GAM21314.1 - 3.8 7.7 12.4 2 8.6 4.4 2.5 2 0 0 2 2 2 0 Thg1 C terminal domain PNISR PF15996.5 GAM21314.1 - 4.3 7.6 21.1 1.6 8.9 5.9 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Eapp_C PF10238.9 GAM21314.1 - 5.4 7.1 17.1 0.41 10.7 1.4 2.6 3 0 0 3 3 3 0 E2F-associated phosphoprotein Abhydro_lipase PF04083.16 GAM21316.1 - 1.6e-14 53.2 0.0 4.4e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 GAM21316.1 - 5.9e-13 49.0 0.2 5.9e-12 45.8 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM21316.1 - 2e-06 27.2 0.0 8.6e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 WD40 PF00400.32 GAM21317.1 - 8.8e-14 51.7 8.2 0.0001 23.0 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM21317.1 - 0.00016 21.9 0.1 2.8 8.3 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Adeno_E1B_55K PF01696.17 GAM21317.1 - 0.013 14.2 0.2 0.022 13.4 0.2 1.3 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Membralin PF09746.9 GAM21317.1 - 0.031 13.3 3.9 0.43 9.6 0.2 2.1 2 0 0 2 2 2 0 Tumour-associated protein zf-UBR PF02207.20 GAM21318.1 - 3.8e-12 46.2 11.3 3.8e-12 46.2 11.3 2.7 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.6 GAM21318.1 - 8.8e-05 22.4 2.7 8.8e-05 22.4 2.7 4.1 4 0 0 4 4 4 1 zinc-RING finger domain ELL PF10390.9 GAM21318.1 - 0.001 18.6 0.2 0.0021 17.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL PhzC-PhzF PF02567.16 GAM21319.1 - 1.3e-51 175.7 0.0 1.5e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 GAM21319.1 - 1.4e-05 24.4 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Proline racemase Reg_prop PF07494.11 GAM21319.1 - 0.12 12.7 0.2 1.9 9.0 0.1 2.5 2 0 0 2 2 2 0 Two component regulator propeller UCH PF00443.29 GAM21320.1 - 3.2e-54 184.1 2.3 4.7e-54 183.6 2.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM21320.1 - 3.7e-13 49.8 0.9 7.5e-09 35.6 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Glyco_transf_10 PF00852.19 GAM21321.1 - 2.6e-33 115.2 0.0 5.7e-33 114.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_trans_1_2 PF13524.6 GAM21321.1 - 0.00014 22.2 0.0 0.0003 21.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Med31 PF05669.12 GAM21321.1 - 0.1 12.6 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 SOH1 Zip PF02535.22 GAM21321.1 - 0.99 8.5 2.5 1.4 8.1 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Conotoxin PF02950.17 GAM21321.1 - 1 10.4 0.1 1 10.4 0.1 2.5 1 1 1 2 2 2 0 Conotoxin Macoilin PF09726.9 GAM21321.1 - 2.3 6.7 5.3 3.1 6.3 5.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF4834 PF16118.5 GAM21321.1 - 5.9 7.9 5.3 30 5.7 5.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) FNIP PF05725.12 GAM21322.1 - 1.3e-58 194.9 38.1 1.2e-14 54.2 4.5 9.2 6 2 4 10 10 10 9 FNIP Repeat Nbl1_Borealin_N PF10444.9 GAM21322.1 - 0.15 11.7 0.0 14 5.4 0.0 3.7 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal TauE PF01925.19 GAM21323.1 - 1e-26 94.0 23.7 1.4e-22 80.5 23.7 2.4 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE Zn_clus PF00172.18 GAM21324.1 - 1.5e-06 28.2 9.2 2.5e-06 27.5 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 GAM21324.1 - 0.0083 15.8 10.5 0.0083 15.8 10.5 6.7 2 1 2 5 5 5 2 Spt20 family Syntaxin PF00804.25 GAM21325.1 - 7.6e-44 149.8 11.0 7.6e-44 149.8 11.0 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 GAM21325.1 - 6e-13 48.6 1.1 1.6e-12 47.2 1.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 GAM21325.1 - 6.5e-05 23.2 9.0 6.5e-05 23.2 9.0 2.5 2 1 0 2 2 2 1 Syntaxin-like protein YscO-like PF16789.5 GAM21325.1 - 0.0043 17.1 5.1 0.0043 17.1 5.1 2.4 3 0 0 3 3 3 1 YscO-like protein VitD-bind_III PF09164.10 GAM21325.1 - 0.0064 16.5 1.1 0.12 12.4 0.2 2.4 2 0 0 2 2 2 1 Vitamin D binding protein, domain III WXG100 PF06013.12 GAM21325.1 - 0.063 13.5 4.9 11 6.3 0.0 4.1 4 1 0 4 4 4 0 Proteins of 100 residues with WXG HTH_45 PF14947.6 GAM21325.1 - 0.21 11.6 4.1 0.26 11.3 1.2 2.5 2 1 0 3 3 3 0 Winged helix-turn-helix DUF3568 PF12092.8 GAM21325.1 - 1.7 8.8 7.2 13 5.9 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3568) Arc_PepC_II PF06847.11 GAM21325.1 - 1.8 9.1 4.5 31 5.2 0.2 2.9 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II PIEZO PF15917.5 GAM21325.1 - 2.2 7.7 11.0 1.4 8.4 8.5 1.8 1 1 1 2 2 2 0 Piezo V-SNARE PF05008.15 GAM21325.1 - 2.6 8.5 13.0 5.4 7.5 1.3 3.4 2 2 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus AI-2E_transport PF01594.16 GAM21325.1 - 3 6.9 8.8 6.6 5.8 0.3 2.7 3 0 0 3 3 3 0 AI-2E family transporter DUF745 PF05335.13 GAM21325.1 - 3.2 7.4 13.3 3.4 7.3 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CCDC-167 PF15188.6 GAM21325.1 - 6.3 7.2 8.8 11 6.5 2.1 3.2 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF848 PF05852.11 GAM21325.1 - 8.3 6.5 8.6 2.2 8.4 2.3 2.6 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TMPIT PF07851.13 GAM21325.1 - 9.6 5.3 16.2 9.4 5.4 6.2 2.3 1 1 1 2 2 2 0 TMPIT-like protein UPF0242 PF06785.11 GAM21325.1 - 10 6.2 17.9 0.34 11.0 8.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RRP7 PF12923.7 GAM21326.1 - 8.7e-27 93.6 12.3 8.7e-27 93.6 12.3 4.1 3 1 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Tim17 PF02466.19 GAM21327.1 - 1.7e-08 34.8 3.1 2.2e-08 34.4 1.6 1.9 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family SLAC1 PF03595.17 GAM21327.1 - 0.0049 16.2 1.1 0.054 12.8 1.4 1.9 1 1 1 2 2 2 1 Voltage-dependent anion channel DUF2189 PF09955.9 GAM21327.1 - 0.21 11.9 2.0 0.64 10.3 0.9 2.0 1 1 2 3 3 3 0 Predicted integral membrane protein (DUF2189) SWIM PF04434.17 GAM21328.1 - 1.7e-06 27.6 0.7 3e-06 26.8 0.7 1.3 1 0 0 1 1 1 1 SWIM zinc finger Syntaxin PF00804.25 GAM21329.1 - 9.1e-29 100.6 7.7 9.1e-29 100.6 7.7 2.3 3 0 0 3 3 3 1 Syntaxin SNARE PF05739.19 GAM21329.1 - 1.3e-08 34.6 0.4 6e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 SNARE domain MCPsignal PF00015.21 GAM21329.1 - 0.84 9.4 4.3 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Swi5 PF07061.11 GAM21330.1 - 8.8e-19 67.4 3.9 1.2e-18 66.9 3.9 1.2 1 0 0 1 1 1 1 Swi5 ERM PF00769.19 GAM21330.1 - 0.00071 19.5 2.9 0.00087 19.2 2.9 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF3523 PF12037.8 GAM21330.1 - 0.00092 18.7 1.2 0.001 18.5 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) APG6_N PF17675.1 GAM21330.1 - 0.00099 19.6 2.1 0.0016 19.0 2.1 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region UPF0242 PF06785.11 GAM21330.1 - 0.0021 18.2 1.4 0.0024 18.0 1.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus E2F_CC-MB PF16421.5 GAM21330.1 - 0.0062 16.9 1.5 0.0097 16.2 1.5 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain Occludin_ELL PF07303.13 GAM21330.1 - 0.0067 17.1 1.9 0.0099 16.6 1.9 1.3 1 0 0 1 1 1 1 Occludin homology domain DUF4600 PF15372.6 GAM21330.1 - 0.014 15.8 2.4 0.021 15.3 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DUF4164 PF13747.6 GAM21330.1 - 0.02 15.2 0.2 0.026 14.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) NPA PF16469.5 GAM21330.1 - 0.023 15.3 5.3 0.054 14.1 5.0 1.7 1 1 1 2 2 2 0 Nematode polyprotein allergen ABA-1 FapA PF03961.13 GAM21330.1 - 0.025 13.2 3.9 0.025 13.2 3.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rho_Binding PF08912.11 GAM21330.1 - 0.03 15.1 5.0 0.034 15.0 3.2 2.0 2 0 0 2 2 2 0 Rho Binding PilO PF04350.13 GAM21330.1 - 0.045 13.9 1.9 0.057 13.6 1.9 1.1 1 0 0 1 1 1 0 Pilus assembly protein, PilO CCDC-167 PF15188.6 GAM21330.1 - 0.054 13.8 2.7 0.075 13.4 2.3 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 RasGAP_C PF03836.15 GAM21330.1 - 0.056 13.6 3.4 0.79 9.9 0.9 2.0 1 1 0 2 2 2 0 RasGAP C-terminus BRICHOS PF04089.14 GAM21330.1 - 0.085 13.1 0.3 0.1 12.8 0.3 1.2 1 0 0 1 1 1 0 BRICHOS domain START PF01852.19 GAM21330.1 - 0.091 12.1 0.1 0.19 11.1 0.1 1.4 1 1 0 1 1 1 0 START domain Vir_act_alpha_C PF10400.9 GAM21330.1 - 0.093 13.4 0.9 0.46 11.2 0.9 1.9 1 1 0 1 1 1 0 Virulence activator alpha C-term V-SNARE PF05008.15 GAM21330.1 - 0.1 13.0 4.6 0.36 11.2 2.5 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Herpes_BLRF2 PF05812.12 GAM21330.1 - 0.13 12.4 5.7 0.73 10.0 5.4 1.9 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF1098 PF06497.11 GAM21330.1 - 0.15 12.6 0.1 0.24 11.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1098) DUF1727 PF08353.10 GAM21330.1 - 0.28 11.1 1.9 0.74 9.8 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1727) FtsJ PF01728.19 GAM21331.1 - 0.00024 21.2 0.0 0.00065 19.9 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase HEPN_AbiA_CTD PF18732.1 GAM21332.1 - 0.043 13.7 0.7 0.19 11.7 0.0 2.3 3 0 0 3 3 3 0 HEPN like, Abia C-terminal domain OSCP PF00213.18 GAM21332.1 - 0.11 12.7 0.3 0.3 11.2 0.1 1.9 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit Seadorna_VP6 PF07407.11 GAM21333.1 - 2.6 6.9 8.0 2.3 7.1 6.6 1.4 1 1 0 1 1 1 0 Seadornavirus VP6 protein Ank_2 PF12796.7 GAM21334.1 - 5.8e-26 90.9 1.7 8e-15 55.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM21334.1 - 8.2e-24 83.7 0.9 5.9e-07 29.9 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM21334.1 - 6.1e-21 73.9 1.9 1.1e-05 25.6 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 GAM21334.1 - 2.3e-19 67.5 1.4 7.4e-06 25.9 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAM21334.1 - 4.7e-19 68.2 0.1 7.4e-08 32.5 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) zinc_ribbon_2 PF13240.6 GAM21334.1 - 8.7e-06 25.3 2.4 1.8e-05 24.2 2.4 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 GAM21334.1 - 0.00061 19.8 0.6 0.00061 19.8 0.6 1.6 2 0 0 2 2 1 1 Double zinc ribbon UPF0547 PF10571.9 GAM21334.1 - 0.015 15.4 0.8 0.029 14.5 0.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zinc_ribbon_15 PF17032.5 GAM21334.1 - 0.021 15.6 0.9 0.021 15.6 0.9 1.7 2 0 0 2 2 2 0 zinc-ribbon family Shigella_OspC PF06128.11 GAM21334.1 - 0.024 14.4 0.2 1 9.0 0.1 2.2 2 1 0 2 2 2 0 Shigella flexneri OspC protein DUF5485 PF17586.2 GAM21334.1 - 0.03 14.6 0.1 0.091 13.1 0.0 1.9 2 0 0 2 2 1 0 Family of unknown function (DUF5485) zf-ribbon_3 PF13248.6 GAM21334.1 - 0.058 12.8 4.4 0.058 12.8 2.5 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 GAM21334.1 - 4 7.4 5.6 0.82 9.6 0.9 2.3 2 0 0 2 2 2 0 Nudix N-terminal Phosphoesterase PF04185.14 GAM21335.1 - 2.3e-76 257.3 6.1 2.5e-47 161.8 0.5 2.2 1 1 1 2 2 2 2 Phosphoesterase family Rhodanese PF00581.20 GAM21336.1 - 1.7e-05 25.3 2.5 0.0006 20.3 0.2 2.9 2 2 1 3 3 3 2 Rhodanese-like domain Pkinase PF00069.25 GAM21337.1 - 1.6e-45 155.5 0.1 1.6e-45 155.5 0.1 3.2 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21337.1 - 3.8e-25 88.7 0.0 1.7e-24 86.6 0.0 2.1 1 0 0 1 1 1 1 Protein tyrosine kinase FUSC PF04632.12 GAM21337.1 - 0.0033 16.1 3.1 0.0052 15.4 3.1 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family Phasin PF05597.11 GAM21337.1 - 0.006 16.6 8.5 0.006 16.6 8.5 3.5 3 1 1 4 4 4 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Fib_alpha PF08702.10 GAM21337.1 - 6.9 6.9 39.7 0.025 14.8 11.8 4.4 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family GvpL_GvpF PF06386.11 GAM21337.1 - 9.4 6.1 14.2 13 5.6 12.6 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Matrilin_ccoil PF10393.9 GAM21337.1 - 9.6 6.2 12.9 1.6 8.6 0.1 4.5 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin ApoO PF09769.9 GAM21337.1 - 9.6 6.2 8.4 2.5e+02 1.6 6.9 3.5 2 1 0 2 2 2 0 Apolipoprotein O AAA_22 PF13401.6 GAM21338.1 - 9.7e-08 32.4 0.0 0.12 12.7 0.0 5.0 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 GAM21338.1 - 2.1e-07 31.4 0.2 0.00017 22.0 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAM21338.1 - 4.1e-07 29.7 2.3 1.2 8.6 0.0 5.1 4 1 0 4 4 4 3 P-loop containing dynein motor region AAA_16 PF13191.6 GAM21338.1 - 6.8e-05 23.3 0.0 0.014 15.8 0.0 4.0 4 1 0 4 4 4 1 AAA ATPase domain AAA_5 PF07728.14 GAM21338.1 - 0.0015 18.5 0.0 33 4.5 0.0 5.2 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) PHB_depo_C PF06850.11 GAM21338.1 - 0.047 13.1 0.2 0.19 11.2 0.2 2.0 1 0 0 1 1 1 0 PHB de-polymerase C-terminus T2SSE PF00437.20 GAM21338.1 - 0.093 11.8 0.3 0.43 9.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein POB3_N PF17292.2 GAM21338.1 - 0.094 13.1 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 0 POB3-like N-terminal PH domain DUF5104 PF17117.5 GAM21338.1 - 9.8 6.7 11.9 8.4 6.9 0.9 4.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5104) Cys_Met_Meta_PP PF01053.20 GAM21339.1 - 1.1e-131 438.9 0.0 1.3e-131 438.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAM21339.1 - 1.8e-05 23.9 0.3 5.5e-05 22.3 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class-V FAD_binding_1 PF00667.20 GAM21340.1 - 1.4e-63 214.5 0.0 2.2e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAM21340.1 - 1.9e-34 118.9 0.4 4e-34 117.9 0.1 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 GAM21340.1 - 4.1e-15 56.4 0.0 1.2e-14 54.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-H2C2_2 PF13465.6 GAM21341.1 - 4e-05 23.8 0.3 4e-05 23.8 0.3 4.1 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.26 GAM21341.1 - 0.00016 22.0 18.2 0.37 11.4 0.1 5.6 5 0 0 5 5 5 3 Zinc finger, C2H2 type TFIIA PF03153.13 GAM21341.1 - 0.0036 17.4 19.4 0.0036 17.4 19.4 4.2 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit FOXP-CC PF16159.5 GAM21341.1 - 0.024 15.2 0.4 0.024 15.2 0.4 7.3 5 1 2 7 7 7 0 FOXP coiled-coil domain SUIM_assoc PF16619.5 GAM21341.1 - 0.055 13.5 0.2 0.055 13.5 0.2 6.6 6 1 1 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 MRC1 PF09444.10 GAM21341.1 - 2.5 8.6 18.9 7.8 7.0 11.2 3.1 2 0 0 2 2 2 0 MRC1-like domain Coiled PF05710.12 GAM21342.1 - 6.5e-18 65.3 26.4 7.4e-18 65.2 26.4 1.0 1 0 0 1 1 1 1 Coiled coil Forkhead_N PF08430.12 GAM21342.1 - 3 8.5 10.6 3.3 8.3 10.6 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region Coiled PF05710.12 GAM21343.1 - 3.8e-18 66.1 26.5 4.4e-18 65.9 26.5 1.0 1 0 0 1 1 1 1 Coiled coil Forkhead_N PF08430.12 GAM21343.1 - 3.5 8.3 11.3 3.9 8.1 11.3 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region SNARE PF05739.19 GAM21344.1 - 1.5e-08 34.5 0.7 2.6e-08 33.7 0.7 1.4 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 GAM21344.1 - 0.0054 16.5 8.2 0.037 13.8 3.8 2.5 2 1 0 2 2 2 1 Synaptobrevin IL31 PF15209.6 GAM21344.1 - 0.035 13.9 0.8 0.12 12.1 0.1 2.1 3 0 0 3 3 3 0 Interleukin 31 Syntaxin_2 PF14523.6 GAM21344.1 - 0.15 12.5 1.8 1.8 9.0 0.1 2.2 2 0 0 2 2 2 0 Syntaxin-like protein ArdA PF07275.11 GAM21344.1 - 0.15 12.6 1.0 0.27 11.8 0.6 1.3 1 1 0 1 1 1 0 Antirestriction protein (ArdA) CD34_antigen PF06365.12 GAM21344.1 - 0.32 10.5 4.3 0.44 10.1 0.7 2.0 1 1 1 2 2 2 0 CD34/Podocalyxin family Tup_N PF08581.10 GAM21344.1 - 0.33 11.3 3.2 3.5 8.0 0.2 2.6 2 1 1 3 3 3 0 Tup N-terminal LPP PF04728.13 GAM21344.1 - 0.4 11.1 2.1 4.1 7.9 0.1 2.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Atx10homo_assoc PF09759.9 GAM21345.1 - 0.0016 18.4 0.2 0.32 11.0 0.1 3.1 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain RhoGAP PF00620.27 GAM21346.1 - 8.5e-41 139.3 0.7 1.4e-40 138.6 0.7 1.3 1 0 0 1 1 1 1 RhoGAP domain Nrap_D2 PF17403.2 GAM21346.1 - 0.062 13.1 0.5 4.2 7.1 0.0 2.6 1 1 0 2 2 2 0 Nrap protein PAP/OAS-like domain DUF1708 PF08101.11 GAM21346.1 - 0.074 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Methyltransf_11 PF08241.12 GAM21347.1 - 2.3e-15 57.0 0.0 3.9e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM21347.1 - 2.8e-13 50.4 0.0 5.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM21347.1 - 7.5e-11 42.0 0.0 9.5e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM21347.1 - 1.9e-07 31.7 0.0 3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM21347.1 - 2.5e-06 27.0 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 GAM21347.1 - 0.0044 15.6 0.0 0.0053 15.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 GAM21347.1 - 0.0068 16.3 0.0 0.55 10.0 0.0 2.2 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 GAM21347.1 - 0.022 14.7 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAM21347.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.16 GAM21347.1 - 0.085 12.0 0.2 0.31 10.1 0.2 1.8 1 1 0 1 1 1 0 mRNA capping enzyme GHMP_kinases_N PF00288.26 GAM21348.1 - 6.7e-13 48.7 3.3 9e-13 48.3 1.6 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAM21348.1 - 0.00019 21.7 0.0 0.00061 20.1 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal CEP76-C2 PF15627.6 GAM21348.1 - 0.089 12.3 0.1 3.8 7.1 0.0 2.4 2 1 0 2 2 2 0 CEP76 C2 domain Alpha-mann_mid PF09261.11 GAM21349.1 - 5.7e-17 61.7 0.0 9.7e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38N PF01074.22 GAM21349.1 - 4.8e-16 59.0 0.1 8.1e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAM21349.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain Clat_adaptor_s PF01217.20 GAM21350.1 - 2.8e-35 121.3 4.6 3.3e-35 121.1 4.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sporozoite_P67 PF05642.11 GAM21351.1 - 3.5 5.6 10.0 5.4 5.0 10.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM154 PF15102.6 GAM21351.1 - 6.5 6.7 6.5 15 5.5 6.5 1.6 1 0 0 1 1 1 0 TMEM154 protein family adh_short PF00106.25 GAM21352.1 - 6.1e-38 130.2 0.3 7.5e-38 130.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM21352.1 - 9.7e-29 100.6 0.1 3e-28 99.0 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAM21352.1 - 5.8e-08 32.5 0.0 2.1e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 GAM21352.1 - 0.0012 19.1 0.2 0.0026 18.0 0.2 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 GAM21352.1 - 0.0015 18.5 0.1 0.002 18.0 0.1 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 GAM21352.1 - 0.021 15.4 0.6 0.08 13.5 0.6 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 GAM21352.1 - 0.047 13.6 0.2 0.071 13.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Radical_SAM_N PF08497.10 GAM21352.1 - 0.076 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Radical SAM N-terminal Ank_2 PF12796.7 GAM21354.1 - 3.2e-38 130.2 0.0 4.5e-15 56.0 0.2 4.8 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM21354.1 - 6.4e-29 96.8 0.4 0.0026 18.1 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 GAM21354.1 - 6.4e-29 100.0 2.0 6.1e-06 26.7 0.0 7.8 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM21354.1 - 6.2e-26 90.1 2.2 2.3e-06 27.8 0.1 7.7 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM21354.1 - 4.2e-24 83.9 0.0 0.00011 22.5 0.1 6.9 6 1 1 7 7 7 4 Ankyrin repeat GRP PF07172.11 GAM21354.1 - 0.91 10.3 10.8 2.3 8.9 10.8 1.7 1 0 0 1 1 1 0 Glycine rich protein family Aldedh PF00171.22 GAM21356.1 - 6.7e-134 446.9 0.0 8.2e-134 446.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAM21356.1 - 0.0066 15.5 0.1 0.048 12.7 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA reductase (LuxC) Transgly_assoc PF04226.13 GAM21356.1 - 0.026 14.8 0.1 0.075 13.3 0.1 1.8 1 0 0 1 1 1 0 Transglycosylase associated protein Act-Frag_cataly PF09192.10 GAM21357.1 - 1.3e-41 142.9 0.6 1.7e-41 142.5 0.6 1.1 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic SPA PF08616.10 GAM21359.1 - 2.1e-34 117.9 0.0 8.7e-34 115.9 0.0 2.1 2 0 0 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.12 GAM21359.1 - 1.3e-25 90.4 1.2 1.3e-25 90.4 1.2 2.3 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 GAM21359.1 - 8.7e-11 41.1 5.7 1.6e-05 23.8 0.1 3.9 2 1 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.9 GAM21359.1 - 1e-05 25.3 11.2 0.0001 22.0 0.0 3.9 4 1 1 5 5 5 2 Uncharacterized conserved protein (DUF2347) PRELI PF04707.14 GAM21359.1 - 0.046 13.5 2.1 0.092 12.6 2.1 1.5 1 0 0 1 1 1 0 PRELI-like family SLED PF12140.8 GAM21359.1 - 0.083 13.4 0.4 4.4 7.9 0.4 2.7 1 1 0 1 1 1 0 SLED domain DUF4890 PF16231.5 GAM21359.1 - 0.4 11.2 5.6 1.2 9.6 5.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) Glycolytic PF00274.19 GAM21360.1 - 2.2e-166 552.9 0.0 2.5e-166 552.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I RNase_H2-Ydr279 PF09468.10 GAM21361.1 - 2.3e-09 37.6 0.4 2.8e-08 34.1 0.4 2.6 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 GAM21361.1 - 9.9e-08 32.1 0.1 3.3e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain CDC45 PF02724.14 GAM21361.1 - 0.25 9.6 11.5 0.36 9.1 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Spt20 PF12090.8 GAM21361.1 - 0.68 9.5 10.7 0.29 10.7 7.9 1.8 2 0 0 2 2 2 0 Spt20 family Sporozoite_P67 PF05642.11 GAM21361.1 - 1.6 6.7 14.8 2.2 6.2 14.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 GAM21361.1 - 8.8 5.5 16.3 16 4.7 16.3 1.3 1 0 0 1 1 1 0 BUD22 COG2 PF06148.11 GAM21363.1 - 2.4e-25 89.2 1.0 2.9e-25 88.9 1.0 1.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 GAM21363.1 - 0.00015 21.8 0.3 0.00023 21.2 0.0 1.5 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 GAM21363.1 - 0.055 13.6 0.1 0.055 13.6 0.1 1.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF3510 PF12022.8 GAM21364.1 - 3.3e-29 101.8 9.1 5.9e-29 101.0 0.5 4.1 4 1 0 4 4 4 1 Domain of unknown function (DUF3510) FSA_C PF10479.9 GAM21364.1 - 0.0023 16.2 1.5 0.0037 15.5 1.5 1.3 1 0 0 1 1 1 1 Fragile site-associated protein C-terminus DUF3439 PF11921.8 GAM21364.1 - 0.5 10.4 7.6 1.8 8.6 7.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RabGAP-TBC PF00566.18 GAM21365.1 - 8.2e-52 176.0 7.2 8.2e-52 176.0 7.2 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain PRAI PF00697.22 GAM21365.1 - 0.0045 16.8 0.5 0.0045 16.8 0.5 2.1 2 0 0 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Dicty_REP PF05086.12 GAM21365.1 - 0.038 12.0 15.4 0.07 11.1 15.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Menin PF05053.13 GAM21365.1 - 0.098 11.0 7.9 0.15 10.4 7.9 1.2 1 0 0 1 1 1 0 Menin Laps PF10169.9 GAM21365.1 - 0.51 10.9 4.9 1.2 9.7 4.9 1.6 1 0 0 1 1 1 0 Learning-associated protein DUF3439 PF11921.8 GAM21365.1 - 1 9.4 16.1 2.5 8.1 16.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAM21365.1 - 1.1 9.3 29.0 2.1 8.4 29.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein ubiquitin PF00240.23 GAM21366.1 - 3.7e-09 36.2 0.1 4.2e-09 36.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM21366.1 - 1.4e-07 31.2 0.1 1.9e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 GAM21366.1 - 0.0022 18.0 0.0 0.73 9.9 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin-like domain CTP_transf_like PF01467.26 GAM21367.1 - 7.6e-05 22.9 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like GSDH PF07995.11 GAM21367.1 - 0.057 12.7 0.0 0.078 12.3 0.0 1.1 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase DsrH PF04077.12 GAM21367.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 DsrH like protein ATP1G1_PLM_MAT8 PF02038.16 GAM21368.1 - 0.11 11.9 0.9 0.19 11.2 0.9 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF2642 PF10842.8 GAM21368.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) Mito_carr PF00153.27 GAM21369.1 - 8.3e-69 227.6 1.8 2.2e-23 82.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 GAM21369.1 - 0.015 15.5 0.1 5.5 7.3 0.0 2.7 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Nucleo_P87 PF07267.11 GAM21370.1 - 0.0025 16.8 7.8 0.003 16.5 7.8 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 Cwf_Cwc_15 PF04889.12 GAM21370.1 - 0.093 12.4 15.1 0.21 11.3 15.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GAM21370.1 - 0.17 10.2 9.2 0.24 9.6 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Cytomega_UL84 PF06284.11 GAM21370.1 - 0.4 9.1 6.0 0.67 8.4 6.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein GP24_25 PF17388.2 GAM21370.1 - 1 9.3 6.1 3.2 7.7 0.0 3.4 3 0 0 3 3 3 0 Tail assembly gene products 24 & 25 KCT2 PF17818.1 GAM21370.1 - 6.5 6.8 11.9 13 5.8 11.9 1.5 1 0 0 1 1 1 0 Keratinocyte-associated gene product Neur_chan_memb PF02932.16 GAM21370.1 - 8.4 6.4 10.2 44 4.0 10.2 2.1 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AMP-binding PF00501.28 GAM21371.1 - 2.8e-60 204.1 0.0 4.7e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAM21371.1 - 9.9e-50 169.1 0.0 2e-49 168.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 GAM21371.1 - 9.7e-10 38.3 0.0 4.4e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM21371.1 - 1.5e-07 30.7 0.3 1.8e-06 27.2 0.3 2.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 GAM21371.1 - 3.7e-07 30.4 0.1 1.6e-06 28.4 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 GAM21371.1 - 0.0022 17.5 0.1 0.76 9.1 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM21371.1 - 0.01 15.7 0.0 5.7 6.8 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_7 PF13241.6 GAM21371.1 - 0.11 12.9 0.0 0.44 11.0 0.0 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding Phage_holin_6_1 PF09682.10 GAM21371.1 - 0.13 12.7 0.0 0.47 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Ribosomal_L14e PF01929.17 GAM21372.1 - 1.2e-20 73.7 0.7 1.2e-20 73.7 0.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 GAM21372.1 - 0.0029 17.5 0.1 0.0065 16.4 0.1 1.6 1 0 0 1 1 1 1 KOW motif Glyco_transf_22 PF03901.17 GAM21373.1 - 8.8e-49 166.8 27.9 1.1e-48 166.5 27.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family GpcrRhopsn4 PF10192.9 GAM21374.1 - 3.3e-51 174.2 36.6 4.6e-51 173.7 36.6 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 GAM21374.1 - 4.5e-06 26.1 27.1 6.3e-06 25.6 27.1 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor SAPS PF04499.15 GAM21375.1 - 4.8e-10 38.8 32.4 1.2e-05 24.4 0.0 4.6 4 1 0 4 4 4 3 SIT4 phosphatase-associated protein Rcd1 PF04078.13 GAM21375.1 - 0.018 14.3 0.1 0.064 12.5 0.0 1.9 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like WD40 PF00400.32 GAM21376.1 - 5.6e-30 103.0 6.4 1.4e-06 28.9 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.14 GAM21376.1 - 6e-26 90.5 10.0 1.2e-25 89.6 10.0 1.5 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 GAM21376.1 - 1.7e-07 31.5 0.0 0.22 11.8 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAM21376.1 - 0.033 14.2 0.1 6.8 6.8 0.0 3.2 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region IMCp PF12314.8 GAM21376.1 - 0.42 10.9 6.8 0.75 10.1 6.8 1.4 1 0 0 1 1 1 0 Inner membrane complex protein DUF2040 PF09745.9 GAM21376.1 - 3.5 7.7 10.2 5.4 7.1 6.4 2.9 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 55 (DUF2040) FKBP_C PF00254.28 GAM21377.1 - 5.5e-34 116.4 0.1 1.9e-33 114.7 0.1 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 GAM21377.1 - 2e-13 50.8 0.0 2e-13 50.8 0.0 1.8 2 1 0 2 2 2 1 Nucleoplasmin-like domain YL1 PF05764.13 GAM21377.1 - 0.00078 19.6 3.2 0.00099 19.3 3.2 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nucleoplasmin PF03066.15 GAM21377.1 - 0.0051 17.3 0.0 0.017 15.6 0.0 1.9 2 0 0 2 2 2 1 Nucleoplasmin/nucleophosmin domain SDA1 PF05285.12 GAM21377.1 - 0.74 9.2 7.5 1 8.8 7.5 1.1 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 GAM21377.1 - 1.5 9.3 9.8 2.7 8.4 9.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 GAM21377.1 - 4 6.7 4.6 6.3 6.0 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein Coiled PF05710.12 GAM21378.1 - 0.0023 18.7 2.1 0.0023 18.7 2.1 1.1 1 0 0 1 1 1 1 Coiled coil DNA_pol_A_exo1 PF01612.20 GAM21379.1 - 8.5e-44 149.3 0.1 1.6e-43 148.5 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 GAM21379.1 - 1.6e-19 70.4 0.1 1.6e-19 70.4 0.1 3.1 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.23 GAM21379.1 - 6.7e-17 61.3 0.0 1.6e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 HRDC domain SUIM_assoc PF16619.5 GAM21379.1 - 0.77 9.9 0.0 0.77 9.9 0.0 4.2 2 2 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 MCU PF04678.13 GAM21379.1 - 5.8 7.0 10.1 2.3 8.3 6.5 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter RRM_1 PF00076.22 GAM21380.1 - 4.2e-09 36.1 0.0 8.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.27 GAM21381.1 - 1.7e-09 38.1 1.3 1.7e-09 38.1 1.3 2.3 2 1 0 2 2 2 1 PCI domain TPR_19 PF14559.6 GAM21381.1 - 0.055 14.0 2.2 0.78 10.3 0.2 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2564 PF10819.8 GAM21381.1 - 0.35 11.3 0.2 0.35 11.3 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) TPR_1 PF00515.28 GAM21383.1 - 1.5e-60 198.7 23.1 2.6e-07 30.2 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21383.1 - 5.5e-50 163.5 19.3 1.4e-05 24.8 0.2 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAM21383.1 - 3.1e-38 126.8 22.3 0.00068 19.7 1.6 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.6 GAM21383.1 - 1.3e-28 99.3 0.8 2.6e-06 28.0 0.0 6.3 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAM21383.1 - 8.8e-28 94.7 13.1 0.0017 18.6 0.1 11.3 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAM21383.1 - 3.2e-27 92.9 0.2 0.00033 21.2 0.2 8.8 3 3 5 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 GAM21383.1 - 3.8e-27 94.4 11.6 1.2e-05 25.4 0.9 6.9 4 3 0 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAM21383.1 - 1.4e-21 76.8 11.5 3.6e-05 24.2 0.0 7.1 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 GAM21383.1 - 5e-19 67.7 24.4 1.3e-05 24.8 0.7 9.6 4 4 6 10 10 10 4 TPR repeat TPR_6 PF13174.6 GAM21383.1 - 9.7e-18 63.6 16.4 0.022 15.4 0.0 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAM21383.1 - 1.1e-17 63.9 0.5 0.0084 16.2 0.1 6.4 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAM21383.1 - 6.9e-17 60.2 10.9 0.21 11.7 0.2 9.8 9 1 1 10 10 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM21383.1 - 6.9e-09 35.8 15.1 0.00029 21.0 2.1 4.4 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GAM21383.1 - 3.4e-08 33.1 7.7 8e-05 22.0 5.7 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM21383.1 - 5.8e-05 22.6 0.2 5.7 6.2 0.0 3.9 1 1 3 4 4 4 2 MalT-like TPR region TPR_21 PF09976.9 GAM21383.1 - 0.013 15.2 9.8 2.5 7.8 0.0 4.1 4 2 0 4 4 4 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 GAM21383.1 - 0.018 14.9 9.0 23 5.0 0.1 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat RPN7 PF10602.9 GAM21383.1 - 0.059 13.1 3.5 37 4.0 0.0 4.6 3 2 2 5 5 5 0 26S proteasome subunit RPN7 ChAPs PF09295.10 GAM21383.1 - 0.14 11.1 0.8 7.3 5.5 0.0 3.0 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 GAM21383.1 - 0.2 11.8 5.5 13 6.0 0.2 5.0 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat DDT PF02791.17 GAM21384.1 - 3e-05 24.2 0.0 7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 DDT domain BSP_II PF05432.11 GAM21384.1 - 0.84 9.3 28.7 0.32 10.7 24.1 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Myosin_head PF00063.21 GAM21385.1 - 3.6e-285 947.5 1.9 3.6e-285 947.5 1.9 2.4 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 GAM21385.1 - 9.9e-70 235.6 341.1 1.3e-41 142.4 164.1 3.1 1 1 2 3 3 3 2 Myosin tail Filament PF00038.21 GAM21385.1 - 7.9e-10 38.8 296.9 2.7e-05 23.9 20.4 12.4 1 1 9 10 10 10 8 Intermediate filament protein Myosin_N PF02736.19 GAM21385.1 - 2.4e-09 36.8 0.2 8e-09 35.2 0.2 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Cortex-I_coil PF09304.10 GAM21385.1 - 0.00074 19.7 14.8 0.00074 19.7 14.8 15.7 6 3 10 17 17 17 2 Cortexillin I, coiled coil BRE1 PF08647.11 GAM21385.1 - 0.0016 18.5 17.7 0.0016 18.5 17.7 16.3 3 2 13 17 17 17 3 BRE1 E3 ubiquitin ligase IQ PF00612.27 GAM21385.1 - 0.0028 17.3 3.0 0.0094 15.7 0.7 2.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif DivIC PF04977.15 GAM21385.1 - 0.0054 16.5 7.2 0.0054 16.5 7.2 22.4 7 5 17 26 26 26 1 Septum formation initiator AAA_22 PF13401.6 GAM21385.1 - 0.24 11.7 0.0 0.24 11.7 0.0 5.0 6 0 0 6 6 6 0 AAA domain ABC_tran PF00005.27 GAM21386.1 - 3.7e-31 108.5 0.1 3.7e-31 108.5 0.1 1.9 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 GAM21386.1 - 0.0019 18.1 1.5 0.0041 17.0 0.1 2.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GAM21386.1 - 0.0065 16.7 0.1 0.21 11.8 0.1 2.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 GAM21386.1 - 0.031 14.2 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 RsgA GTPase CTXphi_pIII-N1 PF16710.5 GAM21386.1 - 0.068 13.3 0.8 0.14 12.3 0.4 1.7 1 1 0 1 1 1 0 N-terminal N1 domain of Vibrio phage CTXphi pIII Myb_DNA-binding PF00249.31 GAM21387.1 - 3.5e-21 75.1 1.5 2.3e-07 30.9 0.0 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM21387.1 - 1.9e-15 56.8 6.6 8.9e-06 25.9 0.0 3.9 4 0 0 4 4 4 3 Myb-like DNA-binding domain VIT1 PF01988.19 GAM21387.1 - 0.2 11.5 0.4 0.42 10.4 0.4 1.7 1 0 0 1 1 1 0 VIT family Myb_DNA-bind_7 PF15963.5 GAM21387.1 - 0.3 11.0 13.6 0.046 13.6 1.6 3.6 2 1 1 3 3 3 0 Myb DNA-binding like TFIIA PF03153.13 GAM21388.1 - 0.029 14.4 19.9 0.043 13.8 19.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 GAM21388.1 - 6.1 5.5 5.6 10 4.8 5.6 1.3 1 0 0 1 1 1 0 Presenilin Methyltrans_RNA PF04452.14 GAM21389.1 - 4.8e-44 150.4 0.0 6.5e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase RhoGAP PF00620.27 GAM21390.1 - 8.8e-49 165.2 0.1 8.8e-49 165.2 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 GAM21390.1 - 3.5e-14 53.2 0.2 1.1e-13 51.6 0.2 1.9 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.17 GAM21390.1 - 1.4e-08 34.3 0.0 2.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAM21390.1 - 1.6e-08 34.2 0.3 3.2e-08 33.3 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM21390.1 - 8.5e-08 31.7 0.1 1.6e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain PH_11 PF15413.6 GAM21390.1 - 0.0001 22.6 1.0 0.0001 22.6 1.0 3.1 3 1 0 3 3 3 1 Pleckstrin homology domain AAA_23 PF13476.6 GAM21390.1 - 0.011 16.3 7.8 0.022 15.2 7.8 1.6 1 0 0 1 1 1 0 AAA domain DUF1708 PF08101.11 GAM21390.1 - 0.014 14.6 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1708) MMPL PF03176.15 GAM21390.1 - 0.043 12.8 1.6 0.067 12.1 1.6 1.3 1 0 0 1 1 1 0 MMPL family DUF848 PF05852.11 GAM21390.1 - 1.9 8.6 7.9 0.16 12.0 1.4 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) ZapB PF06005.12 GAM21390.1 - 2.2 8.8 13.6 98 3.5 13.6 2.6 1 1 0 1 1 1 0 Cell division protein ZapB TIG PF01833.24 GAM21391.1 - 1e-08 35.1 8.0 3.5e-05 23.8 1.4 4.4 4 1 0 4 4 4 2 IPT/TIG domain EGF_2 PF07974.13 GAM21391.1 - 0.0021 18.4 11.7 0.0052 17.1 11.7 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_CA PF07645.15 GAM21391.1 - 3 8.1 10.0 11 6.3 10.0 2.0 1 0 0 1 1 1 0 Calcium-binding EGF domain Maf PF02545.14 GAM21392.1 - 3.7e-32 111.5 0.0 4.6e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein BRK PF07533.16 GAM21392.1 - 0.19 11.4 0.3 0.35 10.5 0.3 1.4 1 0 0 1 1 1 0 BRK domain FNIP PF05725.12 GAM21393.1 - 4.4e-76 250.8 31.3 1.8e-13 50.4 0.1 11.8 7 3 6 13 13 13 13 FNIP Repeat FPL PF09758.9 GAM21393.1 - 0.063 13.3 0.6 0.12 12.3 0.6 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein Gas_vesicle PF00741.18 GAM21394.1 - 0.057 13.6 2.7 0.083 13.0 2.7 1.2 1 0 0 1 1 1 0 Gas vesicle protein IBR PF01485.21 GAM21395.1 - 4.9e-21 74.7 22.1 4.2e-13 49.3 3.8 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 GAM21395.1 - 2.7e-05 24.4 9.7 2.7e-05 24.4 9.7 3.8 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 GAM21395.1 - 0.0006 19.7 10.7 0.0006 19.7 10.7 3.8 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM21395.1 - 0.0016 18.2 7.8 0.0016 18.2 7.8 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM21395.1 - 0.0048 16.7 8.7 0.0048 16.7 8.7 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) CxC5 PF18718.1 GAM21395.1 - 0.02 15.0 0.7 0.02 15.0 0.7 4.3 3 1 0 3 3 2 0 CxC5 like cysteine cluster associated with KDZ transposases Nop14 PF04147.12 GAM21395.1 - 0.052 11.8 19.3 0.1 10.8 19.3 1.4 1 0 0 1 1 1 0 Nop14-like family CD99L2 PF12301.8 GAM21395.1 - 0.37 11.1 8.0 0.1 12.9 3.9 2.2 1 1 1 2 2 2 0 CD99 antigen like protein 2 TFIIA PF03153.13 GAM21395.1 - 0.47 10.4 20.7 0.72 9.8 20.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GAT PF03127.14 GAM21395.1 - 2.1 8.7 6.6 0.39 11.1 0.4 2.6 3 0 0 3 3 3 0 GAT domain Cwf_Cwc_15 PF04889.12 GAM21395.1 - 2.2 8.0 28.4 0.75 9.5 22.6 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Dus PF01207.17 GAM21396.1 - 1.7e-72 244.2 0.1 2.2e-72 243.8 0.1 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 GAM21396.1 - 0.00037 20.0 0.0 0.00073 19.1 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein Med20 PF08612.11 GAM21396.1 - 0.011 15.1 0.5 0.038 13.4 0.0 1.9 2 0 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ThiG PF05690.14 GAM21396.1 - 0.015 14.7 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 GAM21396.1 - 0.037 13.4 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase SOR_SNZ PF01680.17 GAM21396.1 - 0.046 13.5 1.0 1.6 8.5 0.0 2.6 2 1 1 3 3 3 0 SOR/SNZ family G3P_antiterm PF04309.12 GAM21396.1 - 0.08 12.3 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator DUF3176 PF11374.8 GAM21397.1 - 0.24 11.6 2.7 0.92 9.7 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3176) DUF1240 PF06836.12 GAM21397.1 - 0.24 11.9 6.4 0.19 12.3 4.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1240) DUF805 PF05656.14 GAM21397.1 - 0.34 11.4 4.5 0.45 10.9 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) FAM176 PF14851.6 GAM21397.1 - 0.37 10.4 1.2 0.44 10.2 0.5 1.5 2 0 0 2 2 2 0 FAM176 family DUF5527 PF17665.1 GAM21398.1 - 0.64 9.5 2.6 1.9 8.0 0.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5527) BRCA2 PF00634.18 GAM21399.1 - 0.0028 17.3 0.8 0.88 9.3 0.0 2.3 2 0 0 2 2 2 2 BRCA2 repeat Allantoicase PF03561.15 GAM21399.1 - 0.044 13.8 0.2 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Allantoicase repeat DUF3602 PF12223.8 GAM21399.1 - 1 10.0 7.1 7.4 7.2 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) WD40 PF00400.32 GAM21400.1 - 2.9e-16 59.6 14.9 9.4e-07 29.5 0.4 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM21400.1 - 9.8e-11 41.8 3.6 0.095 13.0 0.1 7.1 4 1 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM21400.1 - 5.2e-06 26.0 0.0 4.1e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 WD40-like domain PQQ_3 PF13570.6 GAM21400.1 - 0.0025 18.3 0.0 5.9 7.5 0.0 4.7 5 0 0 5 5 5 1 PQQ-like domain BBS2_N PF14781.6 GAM21400.1 - 0.01 15.7 0.0 0.98 9.4 0.0 3.5 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal Frtz PF11768.8 GAM21400.1 - 0.042 12.2 0.0 0.13 10.6 0.0 1.7 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PAP2 PF01569.21 GAM21401.1 - 1.3e-22 80.0 2.4 1.3e-22 80.0 2.4 1.9 1 1 1 2 2 2 2 PAP2 superfamily ABG_transport PF03806.13 GAM21401.1 - 0.0069 14.7 2.4 0.014 13.7 2.5 1.5 1 1 0 1 1 1 1 AbgT putative transporter family Cyt_c_ox_IV PF12270.8 GAM21401.1 - 0.047 13.8 1.4 0.14 12.3 0.1 2.4 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV PfkB PF00294.24 GAM21402.1 - 4.8e-12 45.8 0.0 1.1e-11 44.6 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase EMP24_GP25L PF01105.24 GAM21403.1 - 1.8e-48 164.9 1.6 2.2e-48 164.6 1.6 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD zf-C2H2_3rep PF18868.1 GAM21404.1 - 0.00082 20.0 1.7 0.00082 20.0 1.7 2.6 1 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 GAM21404.1 - 0.0047 17.3 10.6 0.49 11.0 3.6 3.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 GAM21404.1 - 0.007 16.3 2.4 0.025 14.6 2.4 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 GAM21404.1 - 0.019 15.8 12.9 0.31 12.0 4.4 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger Pox_Ag35 PF03286.14 GAM21404.1 - 0.071 12.9 3.8 0.1 12.4 3.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein zf-met PF12874.7 GAM21404.1 - 0.081 13.3 6.1 1.4 9.5 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Cellulose_synt PF03552.14 GAM21404.1 - 0.13 10.8 3.5 0.13 10.7 3.5 1.1 1 0 0 1 1 1 0 Cellulose synthase EIIBC-GUT_N PF03612.14 GAM21404.1 - 0.32 10.7 2.6 0.51 10.1 2.6 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus zf-C2H2_jaz PF12171.8 GAM21404.1 - 1.3 9.4 0.1 1.3 9.4 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Presenilin PF01080.17 GAM21404.1 - 5.3 5.7 6.4 6.2 5.5 6.4 1.1 1 0 0 1 1 1 0 Presenilin DEAD PF00270.29 GAM21405.1 - 8.2e-40 136.4 0.0 3e-39 134.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM21405.1 - 2.3e-33 114.8 0.0 6.2e-33 113.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM21405.1 - 0.074 13.0 0.0 0.3 11.1 0.0 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 GAM21405.1 - 0.08 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain zf-CCHC PF00098.23 GAM21405.1 - 3.4 7.9 8.3 0.23 11.6 2.8 1.9 2 0 0 2 2 2 0 Zinc knuckle TPT PF03151.16 GAM21406.1 - 1e-59 202.3 29.1 1.3e-59 202.0 29.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAM21406.1 - 3.4e-15 56.4 34.0 1.1e-08 35.3 14.9 2.5 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.11 GAM21406.1 - 4.2e-05 22.9 29.8 7.2e-05 22.1 29.7 1.4 1 1 0 1 1 1 1 UAA transporter family Methyltransf_25 PF13649.6 GAM21407.1 - 1.9e-11 44.5 0.3 3.4e-10 40.5 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM21407.1 - 3.8e-11 43.6 0.3 1.3e-10 41.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM21407.1 - 3.4e-08 34.0 0.0 1.7e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM21407.1 - 7.1e-08 32.5 6.3 2.2e-07 30.9 6.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM21407.1 - 2.3e-07 30.5 0.0 3.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 GAM21407.1 - 2.6e-07 30.5 0.3 6.8e-07 29.2 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 GAM21407.1 - 8.1e-05 22.2 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NNMT_PNMT_TEMT PF01234.17 GAM21407.1 - 0.01 15.0 0.0 0.041 13.1 0.0 1.8 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family NodS PF05401.11 GAM21407.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) CbiC PF02570.15 GAM21407.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Precorrin-8X methylmutase ArAE_1_C PF11728.8 GAM21407.1 - 9.4 6.2 10.8 0.45 10.5 2.4 2.6 3 0 0 3 3 3 0 Putative aromatic acid exporter C-terminal domain GRAM PF02893.20 GAM21408.1 - 8.8e-07 28.8 0.1 2.2e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 GRAM domain C2 PF00168.30 GAM21409.1 - 1.2e-09 38.3 0.0 3.8e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 GAM21409.1 - 2.3e-05 24.6 0.0 0.0045 17.2 0.0 3.3 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain FERM_f0 PF16511.5 GAM21409.1 - 0.00018 21.8 0.7 0.0017 18.6 0.0 3.0 3 0 0 3 3 3 1 N-terminal or F0 domain of Talin-head FERM DUF4358 PF14270.6 GAM21409.1 - 0.048 13.9 0.1 1.1 9.6 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Sec7_N PF12783.7 GAM21409.1 - 0.12 12.2 1.8 1.4 8.8 0.2 2.9 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SH3_1 PF00018.28 GAM21410.1 - 1.5e-16 59.7 0.1 2.7e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Myosin_TH1 PF06017.13 GAM21410.1 - 2.2e-16 60.1 1.4 6.7e-16 58.5 0.8 1.8 1 1 1 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 GAM21410.1 - 7.5e-16 57.7 0.1 1.5e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM21410.1 - 1.2e-13 50.5 0.0 3.7e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain UPF0302 PF08864.10 GAM21410.1 - 0.19 11.8 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 UPF0302 domain Myosin_head PF00063.21 GAM21412.1 - 1.8e-269 895.6 6.0 2.2e-269 895.3 6.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 GAM21412.1 - 0.00092 19.6 0.0 0.0024 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Hpr_kinase_C PF07475.12 GAM21412.1 - 0.0079 15.7 0.2 0.39 10.2 0.1 2.6 3 0 0 3 3 3 1 HPr Serine kinase C-terminal domain ABC_tran PF00005.27 GAM21412.1 - 0.046 14.2 0.2 0.13 12.8 0.2 1.8 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 GAM21412.1 - 0.049 12.9 0.2 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 GAM21412.1 - 0.063 13.6 0.0 0.24 11.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAM21412.1 - 0.074 12.7 0.1 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 GAM21412.1 - 0.13 12.8 0.0 0.36 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PCMT PF01135.19 GAM21413.1 - 1.7e-27 96.6 0.0 2.8e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BTB PF00651.31 GAM21413.1 - 8.6e-25 87.1 5.2 8.7e-15 54.9 0.1 2.9 2 1 1 3 3 3 2 BTB/POZ domain DOT1 PF08123.13 GAM21413.1 - 1.5e-05 24.6 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 PH_3 PF14593.6 GAM21414.1 - 3e-12 46.6 0.0 9.5e-12 45.0 0.0 1.9 1 0 0 1 1 1 1 PH domain PH PF00169.29 GAM21414.1 - 8.6e-07 29.4 1.2 2.3e-06 28.0 0.2 2.3 2 1 1 3 3 3 1 PH domain PH_8 PF15409.6 GAM21414.1 - 0.0026 18.0 0.0 0.0076 16.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Spem1 PF15670.5 GAM21414.1 - 0.014 15.0 7.3 0.043 13.4 7.3 1.9 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF4404 PF14357.6 GAM21414.1 - 0.028 15.1 2.2 0.028 15.1 2.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) PH_6 PF15406.6 GAM21414.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Lip_prot_lig_C PF10437.9 GAM21414.1 - 0.35 10.9 1.8 0.66 10.0 0.2 2.2 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus PKcGMP_CC PF16808.5 GAM21414.1 - 4.6 7.2 16.0 3.3 7.7 0.1 5.0 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DDHD PF02862.17 GAM21415.1 - 3.5e-34 118.9 0.0 1.2e-33 117.1 0.0 1.9 1 1 0 1 1 1 1 DDHD domain Abhydrolase_8 PF06259.12 GAM21415.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF962 PF06127.11 GAM21416.1 - 1.2e-33 115.1 0.7 1.3e-33 114.9 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Cytochrome_B PF00033.19 GAM21417.1 - 0.048 13.5 1.0 0.048 13.5 1.0 1.6 2 0 0 2 2 2 0 Cytochrome b/b6/petB Ribosomal_S21e PF01249.18 GAM21418.1 - 1.9e-38 130.4 0.1 2.1e-38 130.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DNA_pol3_delta2 PF13177.6 GAM21419.1 - 4e-11 43.0 0.0 7.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 GAM21419.1 - 3.6e-05 23.8 0.0 0.00011 22.2 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain Rep_fac_C PF08542.11 GAM21419.1 - 3.8e-05 24.0 0.1 9.1e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 GAM21419.1 - 4.1e-05 24.0 0.0 9.7e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM21419.1 - 0.00014 22.3 0.0 0.0015 19.0 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 GAM21419.1 - 0.003 16.7 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAM21419.1 - 0.0034 17.6 0.0 0.0073 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAM21419.1 - 0.0084 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAM21419.1 - 0.012 15.6 0.1 0.051 13.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAM21419.1 - 0.021 14.6 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 GAM21419.1 - 0.07 13.2 0.0 0.7 10.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 GAM21419.1 - 0.088 13.3 0.0 0.17 12.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter His_Phos_1 PF00300.22 GAM21420.1 - 9.9e-30 103.7 0.1 1.4e-25 90.1 0.0 2.8 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Acyl-CoA_dh_1 PF00441.24 GAM21421.1 - 3.3e-46 157.2 0.6 4.8e-46 156.7 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAM21421.1 - 4.4e-27 94.1 0.2 1.4e-26 92.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAM21421.1 - 6.6e-26 91.2 0.0 1.1e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAM21421.1 - 1e-21 77.6 0.1 1.8e-21 76.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Abhydrolase_1 PF00561.20 GAM21421.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sec8_exocyst PF04048.14 GAM21421.1 - 0.18 11.7 0.3 1 9.3 0.2 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Patatin PF01734.22 GAM21422.1 - 6.3e-18 65.7 0.1 1.9e-17 64.2 0.1 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Telomere_reg-2 PF10193.9 GAM21423.1 - 7e-27 94.0 2.2 1.5e-26 92.9 0.2 2.4 2 1 0 2 2 2 1 Telomere length regulation protein DUF4042 PF13251.6 GAM21423.1 - 0.039 13.7 0.7 1 9.0 0.0 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4042) MTS PF05175.14 GAM21424.1 - 5.4e-09 35.8 0.0 1.5e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 GAM21424.1 - 4.2e-08 32.9 0.0 7.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 GAM21424.1 - 2.5e-07 30.6 0.0 1.4e-06 28.2 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM21424.1 - 3.3e-06 27.7 0.0 4.3e-05 24.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM21424.1 - 9.3e-05 23.1 0.5 0.00088 20.0 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM21424.1 - 0.00045 20.1 0.0 0.00097 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAM21424.1 - 0.00058 19.8 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM21424.1 - 0.0055 17.3 0.0 0.03 15.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 GAM21424.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 GAM21424.1 - 0.03 14.3 0.3 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_10 PF05971.12 GAM21424.1 - 0.088 12.1 0.1 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 RNA methyltransferase Methyltransf_15 PF09445.10 GAM21424.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.9 GAM21424.1 - 0.12 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase LRR_6 PF13516.6 GAM21425.1 - 8.4e-59 190.7 54.2 2.2e-06 27.2 0.5 17.8 19 0 0 19 19 19 15 Leucine Rich repeat LRR_4 PF12799.7 GAM21425.1 - 7.8e-05 23.0 71.4 0.017 15.5 1.6 11.3 9 3 3 12 12 12 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM21425.1 - 0.0023 18.3 36.0 18 6.4 0.0 13.8 16 1 0 16 16 16 2 Leucine Rich Repeat LRR_8 PF13855.6 GAM21425.1 - 0.0047 16.6 68.7 0.22 11.3 0.2 13.0 8 3 3 12 12 12 6 Leucine rich repeat DUF4131 PF13567.6 GAM21426.1 - 0.09 12.4 0.6 0.33 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SAE2 PF08573.10 GAM21426.1 - 0.095 13.8 0.8 1.1 10.4 0.0 2.3 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus GATase_6 PF13522.6 GAM21427.1 - 6.2e-14 52.3 0.1 6.4e-13 49.1 0.0 2.3 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GAM21427.1 - 9.6e-14 50.9 0.0 6.4e-13 48.2 0.0 2.0 2 1 0 2 2 2 1 Glutamine amidotransferases class-II CRAL_TRIO PF00650.20 GAM21428.1 - 1.8e-20 73.3 0.0 3.3e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 GAM21428.1 - 7e-08 32.7 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Helicase_C_2 PF13307.6 GAM21429.1 - 7.3e-55 185.7 0.0 2e-54 184.3 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 GAM21429.1 - 5.6e-48 162.9 0.3 9.4e-48 162.2 0.3 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 GAM21429.1 - 2.8e-07 30.7 4.2 0.0007 19.6 0.5 2.7 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM21429.1 - 0.00051 19.9 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1079 PF06435.11 GAM21429.1 - 0.17 12.1 0.7 0.89 9.8 0.7 2.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) BASP1 PF05466.12 GAM21429.1 - 0.23 11.5 5.2 0.52 10.3 5.2 1.6 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) ATP_bind_1 PF03029.17 GAM21430.1 - 2.5e-85 286.1 0.1 2.8e-85 286.0 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 GAM21430.1 - 8e-05 22.4 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 GAM21430.1 - 0.00028 20.5 0.1 0.0038 16.8 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 GAM21430.1 - 0.00055 20.5 0.0 0.0014 19.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAM21430.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CLP1_P PF16575.5 GAM21430.1 - 0.011 15.5 0.0 0.36 10.6 0.0 2.5 2 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 GAM21430.1 - 0.014 15.8 0.0 0.034 14.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 GAM21430.1 - 0.028 14.3 0.2 3.2 7.6 0.0 2.9 2 1 0 3 3 3 0 RsgA GTPase PduV-EutP PF10662.9 GAM21430.1 - 0.032 14.0 0.1 5.7 6.7 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3368 PF11848.8 GAM21430.1 - 0.045 13.6 0.0 0.82 9.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) ABC_tran PF00005.27 GAM21430.1 - 0.055 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 GAM21430.1 - 0.077 13.3 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 GAM21430.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM21430.1 - 0.11 13.0 0.0 1.6 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 GAM21430.1 - 0.15 11.5 0.0 0.65 9.4 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 GAM21430.1 - 0.15 11.3 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 GAM21430.1 - 0.19 11.6 0.4 6.3 6.7 0.0 2.8 2 1 0 2 2 2 0 NTPase TPR_20 PF14561.6 GAM21431.1 - 2.3e-20 72.7 4.8 3.2e-20 72.3 0.2 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat Thioredoxin PF00085.20 GAM21431.1 - 2.3e-16 59.6 0.2 9.9e-16 57.6 0.0 2.1 3 0 0 3 3 3 1 Thioredoxin TPR_19 PF14559.6 GAM21431.1 - 1.3e-06 28.8 3.6 0.00033 21.1 1.5 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat Thioredoxin_6 PF13848.6 GAM21431.1 - 2.3e-06 27.6 0.0 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain TPR_14 PF13428.6 GAM21431.1 - 0.00059 20.4 0.4 0.26 12.2 0.1 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat Thioredoxin_2 PF13098.6 GAM21431.1 - 0.00074 19.9 0.2 0.014 15.9 0.2 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain ANAPC3 PF12895.7 GAM21431.1 - 0.045 14.0 0.1 4.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAM21431.1 - 0.098 12.8 1.4 19 5.7 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Dicty_CTDC PF00526.18 GAM21432.1 - 4.8e-31 106.3 199.6 1.2e-07 31.5 7.8 13.4 13 2 1 14 14 14 11 Dictyostelium (slime mold) repeat CN_hydrolase PF00795.22 GAM21434.1 - 0.005 16.2 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Phytochelatin PF05023.14 GAM21435.1 - 1.4e-91 305.5 0.0 2.3e-91 304.7 0.0 1.4 1 0 0 1 1 1 1 Phytochelatin synthase Phytochelatin_C PF09328.10 GAM21435.1 - 1e-05 25.0 0.1 0.0039 16.5 0.0 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF1984) Peptidase_C39_2 PF13529.6 GAM21435.1 - 0.006 17.1 0.5 1.2 9.7 0.0 3.0 3 0 0 3 3 3 2 Peptidase_C39 like family DUF4083 PF13314.6 GAM21436.1 - 8.1 6.5 10.2 13 5.8 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Syja_N PF02383.18 GAM21437.1 - 1.4e-85 287.4 0.8 3.1e-85 286.3 0.8 1.6 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 GAM21437.1 - 1.8e-25 88.9 0.1 3.3e-25 88.0 0.1 1.5 1 0 0 1 1 1 1 Inositol phosphatase CDC45 PF02724.14 GAM21437.1 - 0.87 7.8 8.4 1.6 6.9 8.4 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GAM21437.1 - 1 8.7 9.0 2 7.8 9.0 1.4 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 GAM21437.1 - 1.2 8.8 5.1 3.3 7.4 5.1 1.7 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.11 GAM21437.1 - 5.2 5.5 13.1 7.7 4.9 13.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LZ_Tnp_IS66 PF13007.7 GAM21438.1 - 0.23 12.3 4.0 0.57 11.0 4.0 1.6 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain zf-C2H2 PF00096.26 GAM21438.1 - 1.5 9.4 5.7 0.34 11.5 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type PPTA PF01239.22 GAM21439.1 - 2e-47 157.6 8.8 2.5e-10 39.7 0.4 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 GAM21439.1 - 0.38 11.2 1.8 6.5 7.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HECT_2 PF09814.9 GAM21440.1 - 2.4e-14 53.0 1.7 3.5e-14 52.5 1.7 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Securin PF04856.13 GAM21440.1 - 0.099 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor ZZ PF00569.17 GAM21441.1 - 4.1e-10 39.3 25.9 1.4e-08 34.4 11.0 5.2 5 1 0 5 5 5 2 Zinc finger, ZZ type zf-RING_2 PF13639.6 GAM21441.1 - 5.1e-09 36.3 10.4 5.1e-09 36.3 10.4 3.7 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 GAM21441.1 - 3.1e-06 27.4 12.1 3.1e-06 27.4 12.1 3.6 3 1 0 3 3 3 1 RING-H2 zinc finger domain C1_2 PF03107.16 GAM21441.1 - 5.1e-06 26.7 7.4 5.1e-06 26.7 7.4 5.1 4 1 0 4 4 4 2 C1 domain zf-ANAPC11 PF12861.7 GAM21441.1 - 0.00038 20.5 6.9 0.00038 20.5 6.9 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAM21441.1 - 0.0029 17.6 10.8 0.0029 17.6 10.8 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAM21441.1 - 0.012 15.3 7.0 0.012 15.3 7.0 2.6 2 1 0 2 2 2 0 RING-like zinc finger zinc_ribbon_4 PF13717.6 GAM21441.1 - 0.076 13.0 0.5 0.076 13.0 0.5 5.2 7 0 0 7 7 7 0 zinc-ribbon domain Mucin PF01456.17 GAM21441.1 - 0.52 10.3 28.5 0.34 10.9 7.7 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein CwfJ_C_1 PF04677.15 GAM21443.1 - 2.6e-31 108.0 2.9 4.5e-31 107.2 2.9 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 GAM21443.1 - 2.3e-22 79.7 0.0 2.3e-22 79.7 0.0 4.0 4 0 0 4 4 4 1 Protein similar to CwfJ C-terminus 2 polyprenyl_synt PF00348.17 GAM21444.1 - 5.3e-90 300.9 0.0 6.4e-90 300.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase ELMO_CED12 PF04727.13 GAM21445.1 - 6.2e-43 147.0 0.1 1.8e-42 145.4 0.1 1.9 1 0 0 1 1 1 1 ELMO/CED-12 family Ank_2 PF12796.7 GAM21445.1 - 3.9e-20 72.2 0.8 1.3e-11 44.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAM21445.1 - 2.1e-17 62.7 1.7 0.00022 21.5 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 GAM21445.1 - 4.3e-15 55.9 2.1 1.4e-09 38.3 0.0 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM21445.1 - 2e-13 50.2 1.6 7.3e-08 32.5 0.1 4.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM21445.1 - 5.5e-13 47.8 1.8 0.083 13.5 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat DUF3361 PF11841.8 GAM21445.1 - 1.2e-11 44.8 4.9 3.4e-11 43.3 4.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) DUF5578 PF17741.1 GAM21445.1 - 0.03 13.7 4.2 1.3 8.4 0.2 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5578) RTP1_C1 PF10363.9 GAM21445.1 - 0.11 12.7 0.2 13 6.0 0.1 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 F-box-like PF12937.7 GAM21446.1 - 3.8e-08 33.1 0.1 8.7e-08 31.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM21446.1 - 1.7e-07 30.9 0.0 6e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 GAM21446.1 - 0.072 14.0 0.2 0.072 14.0 0.2 3.2 2 0 0 2 2 2 0 WD domain, G-beta repeat Peptidase_C1 PF00112.23 GAM21447.1 - 2.2e-69 233.9 4.7 2.2e-69 233.9 4.7 1.4 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM21447.1 - 1.4e-12 47.9 6.3 2.2e-12 47.2 6.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAM21447.1 - 1.8e-08 33.6 1.5 1.8e-05 23.7 0.1 2.3 2 1 0 2 2 2 2 Peptidase C1-like family Notch PF00066.17 GAM21447.1 - 0.14 12.7 7.4 0.085 13.3 4.6 2.1 2 0 0 2 2 2 0 LNR domain Kinesin PF00225.23 GAM21448.1 - 1.8e-110 369.0 2.8 1.8e-110 369.0 2.8 2.4 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAM21448.1 - 5.1e-27 94.6 0.3 2.8e-26 92.2 0.3 2.4 1 0 0 1 1 1 1 Microtubule binding WD40 PF00400.32 GAM21449.1 - 5.9e-18 64.9 2.9 0.00018 22.2 0.3 6.2 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM21449.1 - 9.9e-07 29.0 0.0 0.012 15.9 0.0 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.9 GAM21449.1 - 6.8e-05 21.7 0.0 0.75 8.3 0.0 3.1 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term eIF2A PF08662.11 GAM21449.1 - 0.0002 21.3 0.0 0.00051 20.0 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 GAM21449.1 - 0.0058 16.5 0.0 3.1 7.8 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 GAM21449.1 - 0.04 12.4 0.0 0.074 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40_like PF17005.5 GAM21449.1 - 0.042 13.2 0.0 2.3 7.5 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain DUF218 PF02698.17 GAM21450.1 - 5.4e-23 81.5 0.0 3.1e-22 79.0 0.0 2.0 2 0 0 2 2 2 1 DUF218 domain Zip PF02535.22 GAM21450.1 - 0.0035 16.6 1.7 0.0051 16.1 1.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4834 PF16118.5 GAM21450.1 - 0.058 14.4 4.6 0.21 12.6 4.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CSG2 PF16965.5 GAM21450.1 - 0.14 11.1 3.4 0.26 10.2 3.4 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator FixQ PF05545.11 GAM21450.1 - 0.15 12.1 0.1 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ SID-1_RNA_chan PF13965.6 GAM21450.1 - 0.16 10.3 3.2 0.36 9.2 3.2 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 GAM21450.1 - 0.23 10.2 6.0 0.41 9.4 6.0 1.3 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 GAM21450.1 - 0.34 9.9 1.7 0.69 8.9 1.7 1.4 1 0 0 1 1 1 0 CLN3 protein Chordopox_G3 PF06129.12 GAM21450.1 - 0.44 11.3 4.1 1.3 9.7 3.7 2.1 1 1 0 1 1 1 0 Chordopoxvirus G3 protein CRA PF06589.11 GAM21450.1 - 0.94 9.6 15.6 0.034 14.3 8.6 2.2 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) SpoIIIAH PF12685.7 GAM21450.1 - 1.6 8.5 14.2 3.5 7.4 14.2 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein Methyltransf_12 PF08242.12 GAM21450.1 - 2.2 9.1 9.7 2.7e+02 2.4 0.0 3.8 2 2 1 3 3 3 0 Methyltransferase domain SPT2 PF08243.11 GAM21451.1 - 1.3e-10 41.7 47.2 1.3e-10 41.7 47.2 4.9 3 3 0 3 3 3 1 SPT2 chromatin protein DUF383 PF04063.14 GAM21452.1 - 0.00051 19.8 0.4 0.001 18.8 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF383) BTB PF00651.31 GAM21452.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 BTB/POZ domain Chromo PF00385.24 GAM21453.1 - 1e-09 38.2 0.2 2.3e-09 37.0 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Zip PF02535.22 GAM21453.1 - 0.0081 15.4 0.5 0.0081 15.4 0.5 3.2 3 0 0 3 3 3 1 ZIP Zinc transporter Chromo_shadow PF01393.19 GAM21453.1 - 0.0086 16.1 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 Chromo shadow domain DUF4702 PF15774.5 GAM21454.1 - 0.016 14.2 0.6 0.018 14.0 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) Tmemb_14 PF03647.13 GAM21455.1 - 2.9e-24 85.6 14.7 3.3e-24 85.4 14.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF5353 PF17304.2 GAM21455.1 - 1.1 9.0 4.7 0.35 10.7 0.3 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5353) Ribosomal_60s PF00428.19 GAM21456.1 - 2.6e-20 72.8 13.0 3e-20 72.6 13.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 GAM21456.1 - 0.13 12.9 5.4 0.22 12.2 5.4 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF4641 PF15483.6 GAM21456.1 - 0.57 9.2 4.6 0.66 9.0 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) HK97-gp10_like PF04883.12 GAM21456.1 - 0.96 10.5 4.1 1.5 9.9 4.1 1.3 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Shadoo PF14999.6 GAM21456.1 - 1 9.4 8.8 1.6 8.8 8.9 1.3 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective Med3 PF11593.8 GAM21456.1 - 2 7.5 5.9 2.4 7.3 5.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Snf7 PF03357.21 GAM21457.1 - 1.3e-44 151.9 15.7 1.5e-44 151.6 15.7 1.0 1 0 0 1 1 1 1 Snf7 RE_Bsp6I PF09504.10 GAM21457.1 - 0.00058 19.5 0.6 0.0011 18.5 0.4 1.5 1 1 0 1 1 1 1 Bsp6I restriction endonuclease Spc7 PF08317.11 GAM21457.1 - 0.0099 14.8 8.5 0.013 14.4 8.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1319 PF07028.11 GAM21457.1 - 0.014 15.6 2.4 0.015 15.5 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Prefoldin PF02996.17 GAM21457.1 - 0.028 14.3 7.3 0.19 11.6 0.0 3.3 2 1 2 4 4 4 0 Prefoldin subunit ATF7IP_BD PF16788.5 GAM21457.1 - 0.031 14.4 3.8 0.032 14.3 3.2 1.3 1 1 0 1 1 1 0 ATF-interacting protein binding domain Hydantoinase_B PF02538.14 GAM21457.1 - 0.031 12.7 0.7 0.039 12.4 0.7 1.0 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase ORF6C PF10552.9 GAM21457.1 - 0.054 13.6 6.5 0.14 12.2 1.3 2.3 2 0 0 2 2 2 0 ORF6C domain Syntaxin-6_N PF09177.11 GAM21457.1 - 0.055 14.0 7.2 1.7 9.2 0.7 2.5 1 1 0 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 GAM21457.1 - 2.1 8.8 14.1 13 6.4 0.0 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region TSC22 PF01166.18 GAM21457.1 - 3.5 8.0 9.8 6.9 7.1 0.2 3.1 3 1 0 3 3 3 0 TSC-22/dip/bun family YlqD PF11068.8 GAM21457.1 - 3.6 8.0 14.7 2.6 8.4 11.7 2.0 1 1 1 2 2 2 0 YlqD protein FapA PF03961.13 GAM21457.1 - 6.2 5.3 10.4 7.1 5.1 7.8 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A FAM76 PF16046.5 GAM21457.1 - 7.2 5.9 8.9 16 4.8 8.9 1.6 1 1 0 1 1 1 0 FAM76 protein PfkB PF00294.24 GAM21458.1 - 7.2e-54 183.1 2.6 8.2e-54 182.9 2.6 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 GAM21458.1 - 0.00049 19.6 0.3 0.00095 18.6 0.3 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ADP_PFK_GK PF04587.15 GAM21458.1 - 0.017 13.8 3.1 0.057 12.0 1.2 2.1 1 1 0 2 2 2 0 ADP-specific Phosphofructokinase/Glucokinase conserved region AcetDehyd-dimer PF09290.11 GAM21458.1 - 0.11 12.7 0.2 1.4 9.1 0.0 2.3 1 1 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Sulfotransfer_1 PF00685.27 GAM21459.1 - 1.1e-17 64.4 0.1 1.6e-16 60.6 0.1 2.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAM21459.1 - 3.9e-13 50.3 0.4 5.7e-10 39.9 0.4 3.1 1 1 0 1 1 1 1 Sulfotransferase family Glyco_trans_4_4 PF13579.6 GAM21459.1 - 2.4e-10 41.1 0.1 4.9e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 GAM21459.1 - 7.9e-10 39.3 0.0 2.6e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAM21459.1 - 9.8e-10 38.7 0.4 9.9e-09 35.4 0.2 2.6 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 GAM21459.1 - 1.2e-09 37.9 0.0 2.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 GAM21459.1 - 0.00034 20.4 0.9 0.0019 17.9 0.9 2.2 1 1 0 1 1 1 1 Starch synthase catalytic domain Gln_amidase PF15644.6 GAM21459.1 - 0.0012 19.8 0.0 0.0035 18.3 0.0 1.8 1 0 0 1 1 1 1 Papain fold toxin 1, glutamine deamidase Glycos_transf_2 PF00535.26 GAM21459.1 - 0.13 12.1 0.0 0.46 10.3 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferase family 2 p450 PF00067.22 GAM21461.1 - 1.1e-94 317.8 0.0 1.4e-94 317.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nop52 PF05997.12 GAM21461.1 - 0.032 14.0 0.1 8.9 6.0 0.2 2.7 2 1 0 2 2 2 0 Nucleolar protein,Nop52 TMEM164 PF14808.6 GAM21462.1 - 3.9e-21 75.5 11.7 5.8e-21 75.0 11.7 1.1 1 0 0 1 1 1 1 TMEM164 family Intg_mem_TP0381 PF09529.10 GAM21462.1 - 5.2e-09 35.9 22.8 7.4e-09 35.4 22.8 1.3 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) Cation_efflux PF01545.21 GAM21462.1 - 0.025 14.3 0.5 0.025 14.3 0.5 2.0 2 0 0 2 2 2 0 Cation efflux family Palm_thioest PF02089.15 GAM21463.1 - 9.4e-73 245.0 0.3 1.1e-72 244.8 0.3 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 GAM21463.1 - 0.0063 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 GAM21463.1 - 0.11 12.1 0.2 0.47 10.0 0.1 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold Ras PF00071.22 GAM21464.1 - 2.8e-45 153.8 0.0 3.3e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM21464.1 - 8.6e-23 80.8 0.0 1.3e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM21464.1 - 6e-08 32.3 0.0 7.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SNF2_N PF00176.23 GAM21464.1 - 0.091 11.5 0.1 0.79 8.4 0.1 1.8 1 1 1 2 2 2 0 SNF2 family N-terminal domain GTP_EFTU PF00009.27 GAM21464.1 - 0.12 11.9 1.0 0.23 11.0 0.0 1.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM21464.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM21464.1 - 0.16 11.8 0.4 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase HD PF01966.22 GAM21465.1 - 0.02 15.1 0.1 0.033 14.4 0.0 1.4 1 1 0 1 1 1 0 HD domain TANGO2 PF05742.12 GAM21466.1 - 1.8e-19 70.8 0.0 2e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 IF-2B PF01008.17 GAM21467.1 - 5e-81 272.0 0.1 6.1e-81 271.7 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Rsbr_N PF08678.10 GAM21467.1 - 0.038 14.1 1.3 0.87 9.7 0.2 3.2 3 1 1 4 4 4 0 Rsbr N terminal SPX PF03105.19 GAM21467.1 - 0.32 10.9 6.5 0.47 10.3 6.5 1.2 1 0 0 1 1 1 0 SPX domain FNIP PF05725.12 GAM21470.1 - 2.9e-41 139.4 10.4 6.1e-11 42.3 0.0 5.7 3 1 1 5 5 5 5 FNIP Repeat LRR_8 PF13855.6 GAM21470.1 - 0.14 11.9 0.9 1.6 8.5 0.1 3.2 2 1 0 2 2 2 0 Leucine rich repeat RhoGAP PF00620.27 GAM21471.1 - 2.2e-23 82.7 0.1 8.4e-23 80.9 0.1 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 GAM21471.1 - 1.6e-10 41.1 0.8 5.5e-10 39.4 0.8 2.1 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Pox_L3_FP4 PF03339.14 GAM21471.1 - 0.035 13.1 4.7 0.063 12.3 4.7 1.4 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein APG5 PF04106.12 GAM21472.1 - 1.3e-58 198.4 4.0 1.6e-58 198.0 4.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF1115 PF06544.12 GAM21472.1 - 0.23 11.5 3.2 2.1 8.5 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1115) ABC2_membrane PF01061.24 GAM21473.1 - 9.6e-35 119.9 28.9 9.6e-35 119.9 28.9 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAM21473.1 - 2.5e-21 76.6 0.0 4.8e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM21473.1 - 2e-06 27.8 0.0 0.0089 15.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM21473.1 - 1.3e-05 24.7 0.0 0.00014 21.3 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM21473.1 - 0.00035 20.3 0.0 0.00079 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM21473.1 - 0.00053 19.9 0.1 0.0012 18.8 0.0 1.5 2 0 0 2 2 1 1 RsgA GTPase AAA_18 PF13238.6 GAM21473.1 - 0.00056 20.5 0.2 0.0035 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM21473.1 - 0.0026 18.1 0.1 0.012 15.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAM21473.1 - 0.0068 16.0 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 GAM21473.1 - 0.0075 16.8 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAM21473.1 - 0.0086 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 GAM21473.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAM21473.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 GAM21473.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 GAM21473.1 - 0.025 14.6 0.1 4 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM21473.1 - 0.026 14.9 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 GAM21473.1 - 0.035 13.8 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAM21473.1 - 0.037 14.0 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 GAM21473.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 GAM21473.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 GAM21473.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC2_membrane_3 PF12698.7 GAM21473.1 - 1.3 8.1 40.9 1.6 7.8 36.3 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein Pkinase_Tyr PF07714.17 GAM21474.1 - 1.6e-51 175.1 0.1 1.2e-48 165.6 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAM21474.1 - 3.4e-43 147.9 0.1 1e-38 133.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain COR PF16095.5 GAM21474.1 - 9.3e-32 110.4 0.2 9.3e-23 81.0 0.0 2.5 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain DEP PF00610.21 GAM21474.1 - 1.1e-29 102.3 0.1 3.7e-18 65.3 0.1 2.9 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Roc PF08477.13 GAM21474.1 - 3.2e-11 43.5 0.3 2.8e-06 27.6 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM21474.1 - 0.0014 18.2 0.2 0.72 9.4 0.0 2.3 2 0 0 2 2 2 2 Ras family AAA_16 PF13191.6 GAM21474.1 - 0.14 12.6 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain zf-C3HC4_3 PF13920.6 GAM21475.1 - 1.5e-09 37.6 11.9 2.2e-09 37.0 10.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM21475.1 - 0.00089 19.5 11.7 0.0035 17.6 11.7 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM21475.1 - 0.0011 18.8 12.0 0.0042 16.9 12.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM21475.1 - 0.0012 18.7 9.9 0.0016 18.3 8.5 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GAM21475.1 - 0.0039 17.0 13.4 0.029 14.2 13.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM21475.1 - 0.025 14.6 13.6 0.074 13.0 13.0 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM21475.1 - 1.3 9.1 8.6 4 7.5 8.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger NHR2 PF08788.11 GAM21476.1 - 0.17 11.6 0.3 0.61 9.9 0.1 1.9 2 0 0 2 2 2 0 NHR2 domain like NICE-3 PF07406.11 GAM21477.1 - 2.4e-05 24.4 1.5 3.6e-05 23.8 1.5 1.4 1 1 0 1 1 1 1 NICE-3 protein DUF4129 PF13559.6 GAM21477.1 - 0.0041 17.3 0.0 0.0062 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) PH PF00169.29 GAM21478.1 - 1.1e-19 70.8 2.2 3e-19 69.5 0.0 2.7 3 0 0 3 3 3 1 PH domain PTEN_C2 PF10409.9 GAM21478.1 - 2.3e-19 69.5 0.9 5.2e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein PH_11 PF15413.6 GAM21478.1 - 5.5e-09 36.4 0.6 5.5e-09 36.4 0.6 4.2 4 1 0 4 4 4 1 Pleckstrin homology domain PH_8 PF15409.6 GAM21478.1 - 4.5e-08 33.3 0.0 1.2e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 GAM21478.1 - 3.3e-05 23.9 1.8 7.9e-05 22.7 0.0 2.5 3 0 0 3 3 3 1 PH domain DSPc PF00782.20 GAM21478.1 - 3.4e-05 23.7 1.5 0.00022 21.0 0.0 2.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM21478.1 - 3.4e-05 23.5 0.2 0.0001 22.0 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAM21478.1 - 0.00025 21.1 0.0 0.00056 20.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family BCL_N PF04714.13 GAM21478.1 - 0.044 13.8 1.4 1.6 8.9 0.2 2.6 2 0 0 2 2 2 0 BCL7, N-terminal conserver region PTPlike_phytase PF14566.6 GAM21478.1 - 0.17 12.0 1.2 0.44 10.7 0.0 2.3 3 0 0 3 3 3 0 Inositol hexakisphosphate FtsJ PF01728.19 GAM21479.1 - 1e-10 42.0 0.0 1.8e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase ANAPC4_WD40 PF12894.7 GAM21480.1 - 4.6e-05 23.6 0.3 0.89 9.9 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 GAM21480.1 - 0.0015 18.5 0.0 3.9 7.6 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.32 GAM21480.1 - 0.0087 16.9 0.8 6 7.9 0.0 4.4 6 0 0 6 6 6 1 WD domain, G-beta repeat CPSF_A PF03178.15 GAM21480.1 - 0.024 13.9 0.1 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 CPSF A subunit region DUF1513 PF07433.11 GAM21480.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1513) DUF1131 PF06572.12 GAM21480.1 - 0.15 11.7 0.1 0.29 10.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1131) UPRTase PF14681.6 GAM21481.1 - 1.3e-80 269.7 0.0 1.5e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAM21481.1 - 4e-07 29.7 0.0 7e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Tup_N PF08581.10 GAM21482.1 - 3e-22 78.7 14.0 3e-22 78.7 14.0 2.9 3 0 0 3 3 3 1 Tup N-terminal PhoU_div PF01865.16 GAM21482.1 - 0.0015 17.9 0.1 0.0027 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF47 Golgin_A5 PF09787.9 GAM21482.1 - 0.011 15.2 5.4 0.011 15.2 5.4 2.5 2 1 0 2 2 2 0 Golgin subfamily A member 5 DUF4407 PF14362.6 GAM21482.1 - 0.027 13.9 13.8 0.042 13.2 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIN_12 PF16289.5 GAM21482.1 - 5.8 7.4 15.1 0.29 11.6 3.5 2.5 1 1 2 3 3 3 0 PIN domain Peptidase_C97 PF05903.14 GAM21483.1 - 3.9e-38 130.7 0.5 4.9e-38 130.3 0.5 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain SVIP PF15811.5 GAM21483.1 - 0.045 14.2 0.1 0.093 13.2 0.1 1.4 1 0 0 1 1 1 0 Small VCP/p97-interacting protein HAT PF02184.16 GAM21484.1 - 6.5e-29 99.6 72.1 1e-08 35.0 0.4 15.5 15 1 0 15 15 15 8 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 GAM21484.1 - 1.4e-25 87.8 7.0 0.0039 17.9 0.0 10.1 4 4 8 12 12 12 6 Tetratricopeptide repeat Suf PF05843.14 GAM21484.1 - 1.1e-19 71.6 22.1 2.2e-05 24.6 0.5 6.2 3 2 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.6 GAM21484.1 - 4.4e-14 52.7 0.0 0.68 10.5 0.0 7.4 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM21484.1 - 4.3e-12 45.5 1.8 0.0012 19.1 0.0 7.4 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21484.1 - 3.5e-08 33.0 5.5 0.6 10.4 0.1 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM21484.1 - 2.1e-07 31.5 2.0 0.53 11.0 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM21484.1 - 1.5e-06 28.5 12.8 33 5.4 0.1 9.7 10 1 0 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM21484.1 - 4e-06 26.6 0.3 17 5.9 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAM21484.1 - 8.1e-06 25.2 12.9 0.12 11.5 0.5 4.5 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM21484.1 - 3.7e-05 23.9 3.0 3.5 8.0 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAM21484.1 - 0.00016 21.7 22.6 0.22 11.5 5.1 6.5 5 2 1 6 6 6 2 Mad3/BUB1 homology region 1 Wzy_C_2 PF11846.8 GAM21484.1 - 0.0024 17.9 2.8 0.049 13.5 0.0 3.5 2 2 2 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal TPR_10 PF13374.6 GAM21484.1 - 0.0073 16.2 0.3 14 5.7 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Occludin_ELL PF07303.13 GAM21484.1 - 0.0094 16.7 5.1 1.5 9.5 0.0 3.2 2 1 0 2 2 2 1 Occludin homology domain TPR_1 PF00515.28 GAM21484.1 - 0.014 15.2 0.8 2.4 8.1 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAM21484.1 - 0.018 15.2 6.4 0.3 11.2 0.1 4.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM21484.1 - 0.029 14.4 5.4 24 5.2 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF5376 PF17346.2 GAM21484.1 - 0.032 14.6 0.6 0.088 13.2 0.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5376) TPR_MalT PF17874.1 GAM21484.1 - 0.035 13.5 0.0 0.19 11.0 0.0 2.2 2 1 0 2 2 2 0 MalT-like TPR region QIL1 PF15884.5 GAM21484.1 - 0.038 14.6 0.6 3.6 8.3 0.0 3.5 4 1 1 5 5 3 0 MICOS complex subunit MIC13, QIL1 SNAP PF14938.6 GAM21484.1 - 0.24 10.8 7.3 1.4 8.3 0.1 4.3 4 1 1 5 5 5 0 Soluble NSF attachment protein, SNAP Scramblase PF03803.15 GAM21485.1 - 3e-30 105.2 0.7 4.4e-30 104.6 0.7 1.2 1 1 0 1 1 1 1 Scramblase Exo_endo_phos PF03372.23 GAM21486.1 - 2e-09 37.3 0.0 3.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SpoIISA_toxin PF14171.6 GAM21486.1 - 0.078 12.7 10.1 0.057 13.1 8.3 1.6 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system DUF2828 PF11443.8 GAM21486.1 - 0.14 10.2 14.2 0.21 9.6 14.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) E1-E2_ATPase PF00122.20 GAM21487.1 - 2.6e-46 157.4 2.6 6.6e-46 156.1 2.6 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAM21487.1 - 6.4e-40 136.8 2.1 6.4e-40 136.8 2.1 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAM21487.1 - 1.6e-23 84.1 0.1 1.2e-20 74.7 0.1 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM21487.1 - 2.5e-23 81.9 0.4 7.9e-23 80.4 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAM21487.1 - 1.6e-17 63.0 0.0 3.3e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM21487.1 - 4.3e-05 23.4 12.6 0.00082 19.2 0.4 3.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAM21487.1 - 0.15 12.5 0.0 1.3 9.3 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Abhydrolase_1 PF00561.20 GAM21488.1 - 7.6e-14 52.0 0.0 4.4e-12 46.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM21488.1 - 1.5e-08 34.2 0.0 4e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM21488.1 - 0.00086 20.0 0.0 0.0013 19.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 GAM21488.1 - 0.021 14.2 0.0 0.12 11.6 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Mucin PF01456.17 GAM21489.1 - 0.00023 21.2 4.9 0.022 14.8 5.8 2.5 2 1 0 2 2 2 1 Mucin-like glycoprotein Orthopox_A5L PF06193.11 GAM21489.1 - 0.0021 17.6 3.0 0.0021 17.6 3.0 1.6 2 0 0 2 2 2 1 Orthopoxvirus A5L protein-like CAF-1_p60_C PF15512.6 GAM21489.1 - 2 8.8 12.9 0.034 14.6 4.9 2.0 2 0 0 2 2 2 0 Chromatin assembly factor complex 1 subunit p60, C-terminal Det1 PF09737.9 GAM21490.1 - 1.4e-117 393.2 13.3 3.7e-84 283.2 5.8 2.3 2 0 0 2 2 2 2 De-etiolated protein 1 Det1 DASH_Ask1 PF08655.10 GAM21490.1 - 0.063 13.2 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Ask1 Pkinase PF00069.25 GAM21491.1 - 3.3e-58 197.1 0.0 4.7e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21491.1 - 3.7e-43 147.7 0.0 5.6e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM21491.1 - 7.7e-05 21.6 1.5 0.0013 17.6 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAM21491.1 - 0.0067 16.4 0.1 0.056 13.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 GAM21491.1 - 0.095 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAM21491.1 - 0.11 11.9 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dicty_REP PF05086.12 GAM21491.1 - 0.72 7.8 8.5 1 7.2 8.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NAM-associated PF14303.6 GAM21491.1 - 5.5 7.7 22.2 0.9 10.2 0.2 2.5 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain Peptidase_M6 PF05547.11 GAM21493.1 - 0.053 11.9 0.0 0.058 11.7 0.0 1.0 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 SAP PF02037.27 GAM21494.1 - 2.2e-06 27.3 0.0 8.2e-05 22.3 0.0 2.7 2 0 0 2 2 2 1 SAP domain Cwf_Cwc_15 PF04889.12 GAM21494.1 - 0.00093 19.0 4.8 0.0015 18.3 4.8 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 GAM21494.1 - 0.0022 17.4 9.7 0.003 17.0 9.7 1.2 1 0 0 1 1 1 1 BUD22 CENP-B_dimeris PF09026.10 GAM21494.1 - 0.052 14.0 20.7 0.55 10.7 2.3 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain LAT PF15234.6 GAM21494.1 - 0.34 10.6 9.1 3.1 7.5 1.3 2.3 2 0 0 2 2 2 0 Linker for activation of T-cells CDC45 PF02724.14 GAM21494.1 - 0.56 8.4 5.4 0.81 7.9 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAM21494.1 - 0.63 8.1 16.8 1 7.4 16.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi eIF-3c_N PF05470.12 GAM21494.1 - 1 7.6 7.3 1.5 7.0 7.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus F-protein PF00469.20 GAM21494.1 - 1.5 8.4 5.0 2.7 7.5 5.0 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef TFIIF_alpha PF05793.12 GAM21494.1 - 2.1 6.9 15.5 3.3 6.2 15.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 GAM21494.1 - 4.2 7.8 18.2 5.4 7.5 6.8 2.7 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SDA1 PF05285.12 GAM21494.1 - 6 6.2 15.3 10 5.4 15.3 1.3 1 0 0 1 1 1 0 SDA1 BSP_II PF05432.11 GAM21494.1 - 8.9 5.9 18.5 0.55 9.9 12.4 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Lactamase_B_2 PF12706.7 GAM21495.1 - 5.1e-10 39.2 3.9 5.2e-09 35.9 0.8 3.4 3 1 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 GAM21495.1 - 0.0009 18.9 0.0 0.021 14.5 0.0 3.0 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B PF00753.27 GAM21495.1 - 0.0058 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Putative_PNPOx PF01243.20 GAM21495.1 - 0.076 13.2 0.1 0.98 9.6 0.0 2.4 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase PhoLip_ATPase_C PF16212.5 GAM21496.1 - 1.8e-72 244.1 26.8 1.8e-72 244.1 26.8 3.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM21496.1 - 2.6e-17 62.2 1.3 9.3e-17 60.5 1.3 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAM21496.1 - 4.6e-14 52.3 0.0 4.7e-12 45.8 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM21496.1 - 1.8e-11 44.7 0.1 4.3e-05 23.9 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAM21496.1 - 4.3e-07 29.6 0.0 4.3e-07 29.6 0.0 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAM21496.1 - 0.00058 19.7 0.1 0.013 15.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAM21496.1 - 0.012 16.0 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3552 PF12072.8 GAM21497.1 - 0.057 12.8 14.6 0.12 11.7 14.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Borrelia_P83 PF05262.11 GAM21497.1 - 1.8 7.0 10.3 2.9 6.3 10.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Adeno_E3_CR2 PF02439.15 GAM21498.1 - 0.00068 19.3 2.4 0.001 18.7 2.4 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SP_C-Propep PF08999.10 GAM21498.1 - 0.064 13.0 1.3 0.097 12.5 1.2 1.3 1 1 0 1 1 1 0 Surfactant protein C, N terminal propeptide Tetraspanin PF00335.20 GAM21498.1 - 0.069 12.9 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family Reovirus_cap PF00979.17 GAM21498.1 - 0.075 12.2 0.0 0.085 12.0 0.0 1.1 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 T7SS_ESX1_EccB PF05108.13 GAM21498.1 - 0.075 11.7 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B EphA2_TM PF14575.6 GAM21498.1 - 0.076 13.9 0.1 0.1 13.5 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AmoC PF04896.12 GAM21498.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Ammonia monooxygenase/methane monooxygenase, subunit C FeoB_associated PF12669.7 GAM21498.1 - 0.2 12.1 2.2 0.33 11.4 2.2 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein UCR_UQCRX_QCR9 PF05365.12 GAM21498.1 - 0.96 9.4 3.8 9.6 6.2 3.8 2.1 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Arf PF00025.21 GAM21499.1 - 1.5e-53 180.9 0.0 1.7e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAM21499.1 - 2.1e-15 56.7 0.0 2.4e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 GAM21499.1 - 2e-14 53.8 0.0 2.8e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM21499.1 - 3.9e-13 49.3 0.0 4.7e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAM21499.1 - 5e-12 45.6 0.5 1.4e-09 37.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAM21499.1 - 6.9e-08 32.1 0.0 8.6e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM21499.1 - 3.3e-06 27.1 0.0 4.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM21499.1 - 0.00087 19.2 0.5 0.21 11.5 0.1 2.4 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 GAM21499.1 - 0.0026 18.0 0.0 0.0034 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 GAM21499.1 - 0.0071 15.9 0.1 0.028 14.0 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 GAM21499.1 - 0.018 15.6 0.1 0.027 15.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter cobW PF02492.19 GAM21499.1 - 0.019 14.5 0.5 3.3 7.3 0.4 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 GAM21499.1 - 0.021 14.5 0.5 0.048 13.3 0.4 1.6 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 GAM21499.1 - 0.035 14.3 0.7 0.42 10.8 0.2 2.0 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 GAM21499.1 - 0.055 13.5 0.0 0.3 11.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 GAM21499.1 - 0.063 13.0 0.1 0.62 9.8 0.1 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 GAM21499.1 - 0.065 13.7 0.1 0.12 12.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAM21499.1 - 0.08 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TniB PF05621.11 GAM21499.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Pik1 PF11522.8 GAM21499.1 - 0.11 12.4 0.4 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF3067 PF11267.8 GAM21499.1 - 0.12 13.0 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) 6PF2K PF01591.18 GAM21499.1 - 0.13 11.5 0.1 0.25 10.6 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase SMC_N PF02463.19 GAM21499.1 - 0.22 10.9 0.1 2.7 7.4 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF1192 PF06698.11 GAM21500.1 - 0.036 14.1 1.0 0.28 11.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FlxA PF14282.6 GAM21500.1 - 0.23 11.4 0.0 0.23 11.4 0.0 3.0 3 0 0 3 3 3 0 FlxA-like protein Nop25 PF09805.9 GAM21500.1 - 0.49 10.9 14.4 0.075 13.5 6.4 2.8 2 1 1 3 3 3 0 Nucleolar protein 12 (25kDa) Syja_N PF02383.18 GAM21501.1 - 3.1e-74 250.2 0.2 3.1e-74 250.2 0.2 3.0 2 1 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 GAM21501.1 - 4.5e-06 26.4 0.0 4.5e-06 26.4 0.0 2.4 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 GAM21502.1 - 1.4e-25 88.9 2.6 3.6e-13 49.1 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM21502.1 - 5.6e-10 39.2 0.5 0.0021 18.2 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif TFIIA PF03153.13 GAM21502.1 - 0.34 10.9 105.3 1.3 9.0 39.9 3.3 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit RRM_3 PF08777.11 GAM21502.1 - 9.8 6.3 7.9 7.3 6.7 0.1 3.2 3 0 0 3 3 3 0 RNA binding motif HHH_2 PF12826.7 GAM21504.1 - 0.00026 21.0 0.0 0.00037 20.5 0.0 1.3 1 1 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GAM21504.1 - 0.0075 16.8 0.1 0.011 16.3 0.1 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain VCBS PF13517.6 GAM21505.1 - 2.1e-27 95.5 15.0 1.7e-08 34.9 0.0 6.1 5 2 2 7 7 7 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAM21505.1 - 7.6e-05 22.8 13.6 0.87 9.8 0.0 5.5 5 0 0 5 5 5 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 GAM21505.1 - 0.0078 15.6 0.4 0.58 9.5 0.0 3.2 2 1 1 3 3 3 1 Insecticide toxin TcdB middle/N-terminal region Dockerin_1 PF00404.18 GAM21505.1 - 0.033 14.4 0.4 11 6.3 0.0 4.1 4 0 0 4 4 4 0 Dockerin type I domain TIG PF01833.24 GAM21506.1 - 0.0002 21.4 20.8 0.01 15.9 0.6 5.2 5 0 0 5 5 5 4 IPT/TIG domain Pkinase PF00069.25 GAM21509.1 - 1.7e-60 204.6 0.4 2.7e-59 200.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21509.1 - 1.3e-46 159.0 0.0 3e-46 157.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM21509.1 - 0.0017 17.2 3.2 0.014 14.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Spot_14 PF07084.12 GAM21509.1 - 0.028 14.6 1.4 0.064 13.4 1.4 1.6 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 APH PF01636.23 GAM21509.1 - 0.18 11.7 1.0 0.57 10.1 0.0 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family TLD PF07534.16 GAM21510.1 - 1.1e-39 135.8 0.3 3.3e-39 134.3 0.3 1.9 1 0 0 1 1 1 1 TLD BRCT PF00533.26 GAM21510.1 - 0.089 13.2 0.4 1.4 9.3 0.4 3.0 2 2 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Dimer_Tnp_hAT PF05699.14 GAM21511.1 - 3.7e-11 42.7 0.1 7e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF851 PF05867.11 GAM21511.1 - 0.0098 15.4 0.2 0.013 14.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF851) Exc PF07825.11 GAM21511.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Excisionase-like protein DUF4112 PF13430.6 GAM21512.1 - 0.0071 16.6 0.0 0.021 15.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4112) HemX PF04375.14 GAM21512.1 - 0.049 12.9 0.2 0.073 12.3 0.2 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF883 PF05957.13 GAM21512.1 - 0.066 13.8 2.3 2.9 8.6 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) CheZ PF04344.13 GAM21512.1 - 0.15 11.9 1.9 0.24 11.3 1.9 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Sds3 PF08598.11 GAM21512.1 - 0.4 10.6 2.8 0.78 9.7 2.8 1.4 1 0 0 1 1 1 0 Sds3-like LPP PF04728.13 GAM21512.1 - 9.4 6.7 6.1 5.4 7.5 0.2 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Secretin_N_2 PF07655.13 GAM21513.1 - 0.017 15.7 27.0 0.02 15.4 27.0 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain DUF4667 PF15700.5 GAM21513.1 - 0.39 10.8 20.8 0.58 10.2 20.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) FAM117 PF15388.6 GAM21513.1 - 1.4 8.3 17.1 1.4 8.2 17.1 1.0 1 0 0 1 1 1 0 Protein Family FAM117 SAP25 PF15476.6 GAM21513.1 - 2.5 7.7 18.7 3 7.5 18.7 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 DHHW PF14286.6 GAM21513.1 - 4.7 6.4 8.0 4.7 6.4 8.0 1.0 1 0 0 1 1 1 0 DHHW protein Lin-8 PF03353.15 GAM21513.1 - 5.5 6.5 9.2 7.4 6.0 9.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 GAM21513.1 - 6.7 6.5 17.8 7 6.4 17.8 1.0 1 0 0 1 1 1 0 SPX domain NAM-associated PF14303.6 GAM21513.1 - 8.7 7.0 16.5 10 6.8 16.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4614 PF15391.6 GAM21513.1 - 9.3 6.2 26.2 11 6.0 26.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DNA_pol_B_2 PF03175.13 GAM21514.1 - 0.00035 19.6 0.5 0.00052 19.0 0.5 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1281 PF06924.11 GAM21514.1 - 0.0053 16.3 0.0 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1281) Crystall_2 PF09076.10 GAM21515.1 - 0.025 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin Toxin_R_bind_N PF07953.12 GAM21517.1 - 0.039 13.7 0.4 0.93 9.2 0.4 2.0 2 0 0 2 2 2 0 Clostridium neurotoxin, N-terminal receptor binding SpoIIE PF07228.12 GAM21518.1 - 8.5e-09 35.6 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GAM21518.1 - 1.8e-05 24.5 0.1 0.11 12.2 0.0 2.7 2 1 1 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAM21518.1 - 0.012 15.2 0.0 0.29 10.7 0.0 2.3 1 1 0 1 1 1 0 Protein phosphatase 2C Phage_pRha PF09669.10 GAM21518.1 - 0.035 14.7 0.0 0.27 11.8 0.0 2.2 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Pkinase PF00069.25 GAM21519.1 - 1.2e-51 175.6 0.0 1.6e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21519.1 - 1.6e-19 70.3 0.0 7.4e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM21519.1 - 1.4e-05 24.1 0.0 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAM21519.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM21519.1 - 0.0018 17.3 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 GAM21519.1 - 0.0077 15.3 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 GAM21519.1 - 0.016 14.8 0.7 1.2 8.7 0.1 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GAM21519.1 - 0.057 12.7 0.0 0.29 10.4 0.0 1.9 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 GAM21519.1 - 0.064 13.2 0.1 0.3 11.0 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family dCMP_cyt_deam_1 PF00383.23 GAM21520.1 - 9.1e-15 54.4 1.2 1.7e-14 53.5 1.2 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAM21520.1 - 2.3e-12 46.8 0.2 5.7e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 MafB19-like deaminase SR-25 PF10500.9 GAM21520.1 - 3.5 7.2 14.5 1.8 8.1 0.6 2.9 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein PA14 PF07691.12 GAM21521.1 - 9.2e-08 32.0 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 GAM21521.1 - 7.5e-06 25.7 4.8 7.5e-06 25.7 4.8 13.4 14 2 1 15 15 15 6 Dictyostelium (slime mold) repeat C1_2 PF03107.16 GAM21522.1 - 0.33 11.3 5.5 1.6 9.1 1.9 2.9 2 1 0 2 2 2 0 C1 domain YyzF PF14116.6 GAM21522.1 - 0.47 10.5 3.0 20 5.3 0.0 3.0 3 0 0 3 3 3 0 YyzF-like protein Sgf11 PF08209.11 GAM21522.1 - 0.58 9.8 6.9 1.4 8.6 0.1 2.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Peptidase_M8 PF01457.16 GAM21523.1 - 2.3e-49 168.5 3.6 4.2e-49 167.6 3.6 1.4 1 1 0 1 1 1 1 Leishmanolysin CPSase_L_D2 PF02786.17 GAM21524.1 - 1.2e-115 384.3 0.3 8.8e-84 280.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 GAM21524.1 - 1.5e-47 160.6 0.0 4.2e-47 159.2 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 GAM21524.1 - 2.1e-44 151.1 0.0 7.3e-44 149.4 0.0 2.0 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 GAM21524.1 - 6.6e-44 150.0 0.0 2.2e-43 148.3 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 GAM21524.1 - 3e-38 130.9 0.1 8.8e-38 129.4 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain RVT_1 PF00078.27 GAM21524.1 - 8.6e-38 130.1 0.0 4.9e-37 127.6 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) OTCace PF00185.24 GAM21524.1 - 4.4e-29 101.6 0.1 1.2e-28 100.2 0.1 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 GAM21524.1 - 1.2e-21 77.2 0.7 1.7e-11 44.1 0.2 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAM21524.1 - 1.7e-16 60.3 0.0 5.5e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 GAM21524.1 - 3.1e-15 56.1 0.0 1.2e-14 54.3 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 GAM21524.1 - 2.4e-10 40.3 0.0 0.00019 21.2 0.0 3.0 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Amidohydro_1 PF01979.20 GAM21524.1 - 1.9e-09 37.3 0.4 1.4e-08 34.5 0.4 2.3 1 1 0 1 1 1 1 Amidohydrolase family ATP-grasp_3 PF02655.14 GAM21524.1 - 3.6e-09 36.9 0.4 2.4e-05 24.4 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 GAM21524.1 - 0.0028 17.5 0.0 0.053 13.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DHOase PF12890.7 GAM21524.1 - 0.025 14.5 0.0 0.072 13.0 0.0 1.8 1 0 0 1 1 1 0 Dihydro-orotase-like PrgU PF09627.10 GAM21524.1 - 0.1 12.6 0.0 19 5.2 0.0 3.0 3 0 0 3 3 3 0 PrgU-like protein Peptidase_C26 PF07722.13 GAM21524.1 - 0.36 10.6 2.3 6.2 6.5 2.3 2.4 1 1 0 1 1 1 0 Peptidase C26 DHO_dh PF01180.21 GAM21525.1 - 4.4e-20 72.1 0.1 1.1e-17 64.2 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Dus PF01207.17 GAM21525.1 - 9.2e-05 21.7 0.5 0.0023 17.1 0.1 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 GAM21525.1 - 0.077 12.4 0.0 0.67 9.4 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein HOOK PF05622.12 GAM21526.1 - 1.3e-67 228.6 83.5 1.9e-67 228.0 83.5 1.1 1 0 0 1 1 1 1 HOOK protein DUF4407 PF14362.6 GAM21526.1 - 0.00016 21.2 67.4 0.00081 18.8 15.6 4.2 2 1 2 4 4 4 4 Domain of unknown function (DUF4407) CH PF00307.31 GAM21526.1 - 0.0012 19.0 0.0 0.0012 19.0 0.0 2.9 3 0 0 3 3 3 1 Calponin homology (CH) domain KASH_CCD PF14662.6 GAM21526.1 - 0.0042 16.9 19.4 0.0042 16.9 19.4 5.9 2 2 3 5 5 5 2 Coiled-coil region of CCDC155 or KASH CH_2 PF06294.11 GAM21526.1 - 0.022 14.9 1.4 0.083 13.0 0.0 2.8 2 0 0 2 2 2 0 CH-like domain in sperm protein Nop14 PF04147.12 GAM21528.1 - 0.0055 15.0 6.3 0.0053 15.0 6.3 1.2 1 0 0 1 1 1 1 Nop14-like family Vfa1 PF08432.10 GAM21528.1 - 0.018 15.4 0.2 0.027 14.8 0.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.12 GAM21528.1 - 0.046 13.0 15.3 0.055 12.8 15.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 GAM21528.1 - 2.7 7.0 18.9 3 6.9 18.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GAM21528.1 - 2.7 6.0 20.8 3.9 5.5 20.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GAM21528.1 - 4.6 5.7 9.0 5.6 5.4 9.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_3_Rpc31 PF11705.8 GAM21528.1 - 5 7.3 23.1 6.1 7.0 23.1 1.2 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 GAM21528.1 - 7.8 4.7 11.5 9.5 4.4 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein FNIP PF05725.12 GAM21529.1 - 1.1e-35 121.6 27.4 2.8e-07 30.6 0.2 8.5 6 1 0 8 8 8 7 FNIP Repeat Actin PF00022.19 GAM21530.1 - 2.7e-152 507.1 0.0 8.6e-152 505.5 0.0 1.6 1 1 0 1 1 1 1 Actin bZIP_2 PF07716.15 GAM21531.1 - 7.5e-07 29.1 2.2 7.5e-07 29.1 2.2 3.5 4 0 0 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.21 GAM21531.1 - 5.9e-05 23.1 4.1 5.9e-05 23.1 4.1 2.8 3 0 0 3 3 3 1 bZIP transcription factor CBP4 PF07960.11 GAM21532.1 - 2.3 8.1 10.7 8 6.3 0.7 2.8 2 1 0 2 2 2 0 CBP4 ABC_membrane_2 PF06472.15 GAM21533.1 - 3.9e-94 315.0 2.4 5.2e-94 314.6 2.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAM21533.1 - 9.7e-19 68.2 0.0 2e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 GAM21533.1 - 0.0003 20.5 0.0 0.00075 19.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 GAM21533.1 - 0.00056 19.4 0.1 0.044 13.2 0.1 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 GAM21533.1 - 0.0012 18.5 1.0 0.0024 17.6 1.0 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 GAM21533.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAM21533.1 - 0.0021 18.6 0.2 0.0068 16.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain SbmA_BacA PF05992.12 GAM21533.1 - 0.0076 15.7 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 SbmA/BacA-like family DUF815 PF05673.13 GAM21533.1 - 0.017 14.3 0.0 0.24 10.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) dCache_1 PF02743.18 GAM21533.1 - 0.044 13.6 0.3 0.68 9.7 0.0 2.6 2 1 1 3 3 3 0 Cache domain AAA_7 PF12775.7 GAM21533.1 - 0.046 13.2 0.3 1.2 8.6 0.0 2.8 2 1 1 3 3 3 0 P-loop containing dynein motor region Adeno_IVa2 PF02456.15 GAM21533.1 - 0.075 11.8 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Sec6 PF06046.13 GAM21533.1 - 0.078 11.3 0.0 0.13 10.6 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec6 AAA_18 PF13238.6 GAM21533.1 - 0.082 13.5 0.0 0.22 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAM21533.1 - 0.094 12.4 0.0 1.2 8.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 GAM21533.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAM21533.1 - 0.13 12.6 0.0 0.47 10.8 0.0 2.0 2 0 0 2 2 1 0 AAA ATPase domain Metallophos PF00149.28 GAM21534.1 - 6.7e-14 52.9 1.0 1e-13 52.3 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_A22B PF04258.13 GAM21535.1 - 1.2e-87 294.1 15.7 1.5e-87 293.8 15.7 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Oxidored_q2 PF00420.24 GAM21535.1 - 0.14 11.8 4.5 0.11 12.1 0.9 2.5 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Claudin_2 PF13903.6 GAM21536.1 - 0.00016 21.5 1.6 0.00026 20.8 1.6 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF5367 PF17329.2 GAM21536.1 - 0.011 15.9 2.6 0.011 15.9 2.6 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5367) SelK_SelG PF10961.8 GAM21536.1 - 0.41 11.3 0.1 0.41 11.3 0.1 2.8 4 0 0 4 4 4 0 Selenoprotein SelK_SelG ATP-synt_E PF05680.12 GAM21537.1 - 8.4 6.8 13.2 1.4 9.3 3.2 2.7 2 1 0 2 2 2 0 ATP synthase E chain RNase_PH PF01138.21 GAM21538.1 - 8.9e-22 78.0 0.3 2.8e-21 76.4 0.3 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAM21538.1 - 1.4e-09 37.8 0.0 3.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 CdAMP_rec PF06153.11 GAM21538.1 - 0.39 10.9 1.7 3.6 7.8 0.1 2.3 2 0 0 2 2 2 0 Cyclic-di-AMP receptor Sedlin_N PF04628.13 GAM21539.1 - 3.9e-37 127.3 0.9 4.4e-37 127.1 0.9 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAM21539.1 - 4.8e-08 33.1 0.7 5.5e-08 32.9 0.7 1.2 1 0 0 1 1 1 1 Sybindin-like family RRM_1 PF00076.22 GAM21540.1 - 5.1e-20 71.1 0.1 6.9e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM21540.1 - 0.0002 21.0 0.1 0.025 14.2 0.0 2.9 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM21540.1 - 0.026 14.5 0.2 9 6.4 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Baculo_PEP_C PF04513.12 GAM21541.1 - 1.7e-07 31.4 7.5 2.1e-05 24.6 1.8 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 GAM21541.1 - 0.00042 20.3 8.8 0.0025 17.8 2.6 3.1 1 1 2 3 3 3 1 Laminin Domain II FAP206 PF12018.8 GAM21541.1 - 0.00083 18.9 4.5 0.0042 16.6 0.9 1.9 1 1 0 2 2 2 1 Domain of unknown function LPP PF04728.13 GAM21541.1 - 0.004 17.5 3.8 1.1 9.7 0.1 3.6 2 2 2 4 4 4 1 Lipoprotein leucine-zipper DUF1664 PF07889.12 GAM21541.1 - 0.0046 17.0 11.1 0.016 15.2 2.4 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 GAM21541.1 - 0.0055 16.6 2.3 0.034 14.0 2.3 2.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF5082 PF16888.5 GAM21541.1 - 0.022 15.1 12.5 0.27 11.5 4.5 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) MetOD2 PF18548.1 GAM21541.1 - 0.025 14.7 6.5 0.97 9.6 0.1 3.6 2 1 1 3 3 3 0 Metanogen output domain 2 COG2 PF06148.11 GAM21541.1 - 0.028 14.5 10.3 0.15 12.1 0.5 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 OAF PF14941.6 GAM21541.1 - 0.034 13.6 1.0 0.053 13.0 1.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, Out at first FlaC_arch PF05377.11 GAM21541.1 - 0.11 13.0 14.7 0.32 11.4 0.1 4.2 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 GAM21541.1 - 0.19 11.9 14.1 0.13 12.5 4.5 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 GAM21541.1 - 0.26 11.8 8.7 5.5 7.5 0.1 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein She9_MDM33 PF05546.11 GAM21541.1 - 0.28 11.0 8.9 0.045 13.6 1.0 2.4 2 1 0 2 2 2 0 She9 / Mdm33 family Nup54 PF13874.6 GAM21541.1 - 0.29 11.2 6.9 3.4 7.8 5.0 2.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 PMC2NT PF08066.12 GAM21541.1 - 0.51 11.1 10.7 1.3 9.7 1.6 2.9 2 1 1 3 3 3 0 PMC2NT (NUC016) domain DUF1640 PF07798.11 GAM21541.1 - 0.76 9.8 15.5 62 3.6 15.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1515 PF07439.11 GAM21541.1 - 0.78 9.8 4.4 0.73 9.9 0.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) FadA PF09403.10 GAM21541.1 - 0.91 10.0 9.3 0.22 12.0 1.6 3.1 2 2 2 4 4 4 0 Adhesion protein FadA Exonuc_VII_L PF02601.15 GAM21541.1 - 1 8.9 7.7 2.1 7.9 7.7 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit YtxH PF12732.7 GAM21541.1 - 1.1 9.9 5.9 2.9 8.5 0.3 3.2 2 2 0 2 2 2 0 YtxH-like protein HSBP1 PF06825.12 GAM21541.1 - 1.3 9.0 9.2 12 5.8 2.0 4.0 3 1 0 3 3 3 0 Heat shock factor binding protein 1 DUF948 PF06103.11 GAM21541.1 - 1.5 9.1 7.5 10 6.4 0.3 3.4 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Occludin_ELL PF07303.13 GAM21541.1 - 1.9 9.3 9.7 0.31 11.8 1.7 2.9 1 1 3 4 4 4 0 Occludin homology domain TssO PF17561.2 GAM21541.1 - 2.9 8.0 16.3 2.8 8.0 9.2 2.6 1 1 1 2 2 2 0 Type VI secretion system, TssO TMF_TATA_bd PF12325.8 GAM21541.1 - 3.3 7.9 11.7 1.6 9.0 0.6 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 GAM21541.1 - 3.5 8.0 10.2 3.3 8.1 0.1 3.8 3 2 1 4 4 4 0 TSC-22/dip/bun family DUF2203 PF09969.9 GAM21541.1 - 6.1 7.6 7.0 2.2 9.0 0.6 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) HAGH_C PF16123.5 GAM21542.1 - 1.4e-22 80.0 0.0 2.4e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 GAM21542.1 - 2.7e-12 47.1 2.3 1.4e-11 44.8 2.3 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM21542.1 - 0.0002 20.9 0.3 0.00041 19.9 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM21542.1 - 0.0036 17.2 0.1 0.0062 16.4 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Swi3 PF07962.12 GAM21545.1 - 1e-06 28.7 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 SR-25 PF10500.9 GAM21545.1 - 0.0067 16.1 14.2 0.0067 16.1 14.2 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF3439 PF11921.8 GAM21545.1 - 0.011 15.7 4.9 0.011 15.7 4.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Peptidase_M66 PF10462.9 GAM21546.1 - 1.7e-81 273.5 0.1 2.3e-81 273.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase M66 Metallopep PF12044.8 GAM21546.1 - 0.014 14.1 1.2 0.022 13.4 1.2 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 GAM21546.1 - 0.02 15.4 0.6 0.046 14.3 0.6 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAM21546.1 - 0.12 12.2 0.2 0.15 11.9 0.2 1.4 1 1 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 GAM21546.1 - 0.15 11.7 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAM21546.1 - 0.16 12.1 0.2 0.3 11.2 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M6 PF05547.11 GAM21546.1 - 0.86 7.9 3.6 7 4.8 0.7 2.1 2 0 0 2 2 2 0 Immune inhibitor A peptidase M6 Stealth_CR2 PF11380.8 GAM21547.1 - 4.7e-37 126.5 2.8 5.5e-37 126.3 1.7 1.7 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 GAM21547.1 - 8.3e-13 48.0 0.3 3.9e-12 45.9 0.1 2.2 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 GAM21547.1 - 8.5e-09 35.2 0.0 2.9e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 tRNA-synt_2d PF01409.20 GAM21549.1 - 2.4e-50 171.3 2.6 6.4e-31 107.7 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 GAM21549.1 - 8.7e-22 77.4 0.0 3e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain HAD_SAK_1 PF10307.9 GAM21550.1 - 1.1e-44 152.7 0.0 1.9e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins DAO_C PF16901.5 GAM21550.1 - 0.077 12.9 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase SSP160 PF06933.11 GAM21550.1 - 0.12 10.5 19.6 0.032 12.5 2.2 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 FtsH_ext PF06480.15 GAM21550.1 - 0.89 9.9 5.9 19 5.6 0.0 3.2 3 0 0 3 3 3 0 FtsH Extracellular FNIP PF05725.12 GAM21551.1 - 2.3e-46 155.7 19.1 2.9e-12 46.5 0.0 6.1 6 1 1 7 7 7 5 FNIP Repeat F-box-like PF12937.7 GAM21551.1 - 0.0026 17.6 0.4 0.0078 16.1 0.4 1.9 1 0 0 1 1 1 1 F-box-like Sulfotransfer_2 PF03567.14 GAM21552.1 - 2.7e-10 40.6 0.1 2.7e-10 40.6 0.1 2.2 2 1 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 GAM21552.1 - 0.00037 19.5 1.2 0.0056 15.6 1.6 2.4 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase Glyco_hydro_20 PF00728.22 GAM21553.1 - 3.7e-71 240.4 0.8 5.2e-71 239.9 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAM21553.1 - 4.1e-15 56.6 0.7 9.5e-14 52.2 0.7 2.3 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAM21553.1 - 6.7e-05 23.7 0.0 0.00012 22.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 GAM21554.1 - 8.2e-88 295.1 0.4 1e-87 294.8 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAM21554.1 - 6.5e-17 62.5 1.6 2.1e-15 57.6 1.6 2.3 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAM21554.1 - 9.4e-07 29.6 0.0 1.4e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Endonuclease_5 PF04493.14 GAM21555.1 - 1.3e-61 207.8 0.0 1.8e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF3402 PF11882.8 GAM21555.1 - 0.018 14.2 3.4 0.027 13.6 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) SHOCT PF09851.9 GAM21555.1 - 0.082 12.7 0.2 0.17 11.7 0.2 1.6 1 1 0 1 1 1 0 Short C-terminal domain TFIIF_alpha PF05793.12 GAM21555.1 - 3.1 6.3 10.5 4.4 5.8 10.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3452 PF11934.8 GAM21555.1 - 5.4 6.6 7.8 7.3 6.2 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3452) PHP_C PF13263.6 GAM21558.1 - 2.8 7.8 6.0 20 5.0 0.4 3.8 3 0 0 3 3 3 0 PHP-associated TIG PF01833.24 GAM21561.1 - 0 983.8 441.0 5.8e-15 55.1 1.9 37.3 37 1 0 37 37 37 36 IPT/TIG domain DNase_II PF03265.15 GAM21561.1 - 3.8e-33 115.1 0.0 8.7e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 Deoxyribonuclease II Qn_am_d_aIII PF09099.10 GAM21561.1 - 3.6e-05 24.1 36.8 25 5.3 0.0 15.3 18 0 0 18 18 18 4 Quinohemoprotein amine dehydrogenase, alpha subunit domain III TIG PF01833.24 GAM21562.1 - 5.7e-82 269.9 71.0 3.4e-14 52.7 4.1 13.6 12 1 1 13 13 13 13 IPT/TIG domain DNase_II PF03265.15 GAM21562.1 - 6.2e-30 104.6 0.2 2.5e-18 66.4 0.1 2.4 2 0 0 2 2 2 2 Deoxyribonuclease II RebB PF11747.8 GAM21563.1 - 0.0053 16.8 6.5 0.0096 16.0 5.2 2.2 2 0 0 2 2 2 1 Killing trait Pkinase PF00069.25 GAM21564.1 - 5.5e-74 248.8 0.0 7.9e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21564.1 - 8.2e-37 126.9 0.0 1.1e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 GAM21564.1 - 2.1e-11 43.4 0.0 4.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 GAM21564.1 - 4.7e-05 22.5 0.1 8.6e-05 21.6 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM21564.1 - 7.4e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAM21564.1 - 0.00056 19.9 0.0 0.0021 18.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM21564.1 - 0.0071 15.9 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 GAM21564.1 - 0.0082 15.5 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_20 PF00728.22 GAM21565.1 - 1.1e-70 238.8 0.2 7.6e-70 236.0 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain PP2C_2 PF13672.6 GAM21566.1 - 0.00071 19.3 0.1 0.0015 18.2 0.1 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C G-alpha PF00503.20 GAM21567.1 - 3.7e-112 375.0 3.5 4.3e-112 374.8 3.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM21567.1 - 1.3e-14 54.1 0.5 2e-11 43.6 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM21567.1 - 3.8e-06 26.4 3.7 0.00012 21.5 0.4 2.4 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM21567.1 - 5.2e-05 23.4 0.4 0.062 13.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAM21567.1 - 0.14 12.3 0.1 10 6.3 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase Epimerase PF01370.21 GAM21567.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ras PF00071.22 GAM21567.1 - 0.24 11.0 2.5 2.1 7.9 0.4 2.5 2 1 0 2 2 2 0 Ras family CLTH PF10607.9 GAM21568.1 - 2.6e-30 105.2 0.3 9.6e-30 103.4 0.0 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 GAM21568.1 - 5e-05 23.2 0.1 0.00012 22.0 0.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAM21568.1 - 0.0096 15.9 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAM21568.1 - 0.034 14.0 0.5 0.034 14.0 0.5 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAM21568.1 - 0.044 14.0 0.4 0.11 12.7 0.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GAM21568.1 - 0.053 13.9 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Ring finger domain L31 PF09784.9 GAM21568.1 - 0.47 10.9 1.9 0.81 10.1 0.7 2.1 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 LRR_4 PF12799.7 GAM21569.1 - 3.3e-22 78.2 56.0 7.4e-05 23.0 2.0 10.5 8 3 4 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM21569.1 - 2.9e-17 62.2 44.4 5.1e-08 32.6 0.8 7.7 6 2 1 7 7 7 4 Leucine rich repeat LRR_9 PF14580.6 GAM21569.1 - 1.4e-16 60.5 24.8 3e-07 30.1 0.6 6.6 5 2 2 7 7 7 4 Leucine-rich repeat FNIP PF05725.12 GAM21569.1 - 0.027 14.6 0.0 2.4 8.4 0.0 3.1 2 1 0 2 2 2 0 FNIP Repeat LRR_6 PF13516.6 GAM21569.1 - 0.48 10.6 34.0 9.2 6.6 0.2 10.3 13 0 0 13 13 13 0 Leucine Rich repeat ThiF PF00899.21 GAM21570.1 - 7.1e-51 172.9 0.0 9.9e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 GAM21570.1 - 0.0074 15.9 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 GAM21570.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ECSIT PF06239.11 GAM21570.1 - 0.038 13.1 0.2 0.082 12.0 0.1 1.6 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway HemeBinding_Shp PF11545.8 GAM21570.1 - 0.042 13.8 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp TrkA_N PF02254.18 GAM21570.1 - 0.17 12.1 0.0 0.9 9.8 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 GAM21570.1 - 0.18 11.0 0.5 0.28 10.4 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 GAM21570.1 - 0.21 10.4 0.1 9 5.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase DAP PF15228.6 GAM21571.1 - 0.024 15.8 1.9 0.071 14.3 1.9 1.8 1 1 0 1 1 1 0 Death-associated protein NTP_transferase PF00483.23 GAM21573.1 - 9.9e-51 172.7 0.0 1.3e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 GAM21573.1 - 2.2e-09 37.9 0.0 2.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 GAM21573.1 - 1.4e-08 34.2 9.3 6.5e-07 28.8 1.4 3.8 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 GAM21573.1 - 0.033 12.3 0.8 0.12 10.5 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 GAM21573.1 - 0.17 11.6 10.4 0.095 12.5 1.8 4.2 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase Cyclin_N PF00134.23 GAM21574.1 - 7.8e-33 112.9 0.3 7.8e-33 112.9 0.3 4.2 4 2 0 4 4 4 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAM21574.1 - 9e-21 74.2 0.0 9e-21 74.2 0.0 4.4 3 2 2 5 5 5 1 Cyclin, C-terminal domain FNIP PF05725.12 GAM21575.1 - 6.2e-82 269.6 46.6 8.5e-13 48.3 0.5 12.5 10 2 4 14 14 14 11 FNIP Repeat LRR_1 PF00560.33 GAM21575.1 - 9.1 7.3 24.3 17 6.4 0.1 9.4 8 4 0 8 8 8 0 Leucine Rich Repeat DENN PF02141.21 GAM21576.1 - 1.6e-29 103.2 5.4 9.2e-28 97.5 0.0 3.4 3 0 0 3 3 3 2 DENN (AEX-3) domain uDENN PF03456.18 GAM21576.1 - 2.1e-06 28.4 3.7 3.2e-06 27.8 1.3 2.7 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 GAM21576.1 - 6.6e-06 26.0 0.4 1.8e-05 24.7 0.4 1.7 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 GAM21576.1 - 0.00041 20.3 0.1 0.0011 19.0 0.1 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Pkinase PF00069.25 GAM21577.1 - 1.5e-76 257.2 0.0 1.5e-76 257.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21577.1 - 1.7e-39 135.7 0.1 4.4e-39 134.3 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 GAM21577.1 - 0.0037 16.9 0.4 0.0065 16.1 0.4 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAM21577.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SNF2_N PF00176.23 GAM21578.1 - 4.7e-49 167.0 1.8 1.1e-48 165.8 1.8 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM21578.1 - 2.8e-16 59.8 0.0 8.6e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SAM_1 PF00536.30 GAM21578.1 - 2.3e-06 28.0 0.1 5.3e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM21578.1 - 7.2e-05 22.8 0.1 0.00017 21.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_34 PF13872.6 GAM21578.1 - 0.00013 20.9 0.2 0.0025 16.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 Pox_A_type_inc PF04508.12 GAM21578.1 - 0.00059 19.6 3.7 0.17 11.8 0.1 3.1 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Tyr-DNA_phospho PF06087.12 GAM21579.1 - 6.1e-69 233.0 1.0 1.2e-68 232.0 1.0 1.4 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 GAM21579.1 - 0.011 15.6 0.2 0.068 13.1 0.1 2.2 2 0 0 2 2 2 0 PLD-like domain UIM PF02809.20 GAM21579.1 - 0.028 14.3 1.3 0.076 13.0 1.3 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF1479 PF07350.12 GAM21580.1 - 4.3e-12 45.5 0.3 1.9e-10 40.1 0.2 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 GAM21580.1 - 4.2e-05 23.9 0.1 0.0013 19.0 0.1 2.2 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) PPL4 PF18188.1 GAM21580.1 - 0.06 13.3 0.5 5.1 7.0 0.0 2.6 3 0 0 3 3 3 0 Prim-pol 4 Oxysterol_BP PF01237.18 GAM21581.1 - 2.6e-65 220.7 10.2 1.4e-59 201.9 0.5 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein E1_dh PF00676.20 GAM21582.1 - 1.1e-106 356.2 0.1 1.3e-106 355.9 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GAM21582.1 - 0.018 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Pkinase PF00069.25 GAM21583.1 - 1.5e-46 158.9 0.0 3.1e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RhoGEF PF00621.20 GAM21583.1 - 6.2e-37 127.6 3.6 6.2e-37 127.6 3.6 2.0 2 0 0 2 2 2 1 RhoGEF domain Pkinase_Tyr PF07714.17 GAM21583.1 - 8.3e-37 126.9 0.0 1.6e-36 126.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase IQ_SEC7_PH PF16453.5 GAM21583.1 - 3e-08 33.7 0.0 1.4e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 PH domain PH PF00169.29 GAM21583.1 - 9.8e-07 29.3 0.0 6.6e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 GAM21583.1 - 0.004 16.0 0.0 0.008 15.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase TACC_C PF05010.14 GAM21583.1 - 0.005 16.6 0.3 0.005 16.6 0.3 2.6 3 0 0 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal APH PF01636.23 GAM21583.1 - 0.038 13.9 0.0 0.13 12.2 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tmemb_cc2 PF10267.9 GAM21583.1 - 0.061 12.5 2.5 0.16 11.1 2.1 1.9 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein PIEZO PF15917.5 GAM21583.1 - 0.12 11.9 0.4 0.24 10.9 0.4 1.5 1 0 0 1 1 1 0 Piezo Enkurin PF13864.6 GAM21583.1 - 0.14 12.6 3.0 0.54 10.7 3.0 2.0 1 0 0 1 1 1 0 Calmodulin-binding GAS PF13851.6 GAM21583.1 - 0.22 10.8 11.8 0.012 15.0 5.3 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Gp-FAR-1 PF05823.12 GAM21583.1 - 4.2 7.7 6.4 2.4 8.5 0.6 2.8 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Macoilin PF09726.9 GAM21583.1 - 9.2 4.7 14.4 0.016 13.8 3.6 1.8 2 0 0 2 2 1 0 Macoilin family BCS1_N PF08740.11 GAM21585.1 - 1.1e-31 110.3 0.0 1.4e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 BCS1 N terminal TMEM43 PF07787.12 GAM21585.1 - 0.09 12.1 0.8 2.6 7.4 0.0 2.1 1 1 1 2 2 2 0 Transmembrane protein 43 SspH PF08141.12 GAM21585.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 Small acid-soluble spore protein H family Utp11 PF03998.13 GAM21586.1 - 1.2e-48 166.2 14.6 1.4e-48 166.0 14.6 1.0 1 0 0 1 1 1 1 Utp11 protein Adeno_E4 PF05385.11 GAM21586.1 - 0.19 11.8 0.3 0.42 10.7 0.2 1.6 2 0 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein SH3_1 PF00018.28 GAM21587.1 - 3.6e-15 55.3 0.1 6.6e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM21587.1 - 1.7e-09 37.4 0.1 3.2e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM21587.1 - 4.3e-09 35.9 0.0 6.8e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 GAM21587.1 - 0.032 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Peptidase_M1 PF01433.20 GAM21589.1 - 1.7e-77 259.9 0.3 3.8e-77 258.7 0.3 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 GAM21589.1 - 1.6e-71 241.4 0.1 2.4e-70 237.6 0.0 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 GAM21589.1 - 1.4e-57 194.9 0.5 6.8e-57 192.7 0.5 2.0 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Ribonuc_P_40 PF08584.11 GAM21590.1 - 9.9e-60 202.2 0.1 2.1e-59 201.1 0.0 1.5 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit SSP160 PF06933.11 GAM21590.1 - 4.9 5.2 11.0 4.8 5.3 7.1 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Pox_L3_FP4 PF03339.14 GAM21591.1 - 0.0021 17.2 0.2 0.0021 17.2 0.2 1.0 1 0 0 1 1 1 1 Poxvirus L3/FP4 protein DUF2545 PF10810.8 GAM21591.1 - 0.012 15.8 0.7 0.014 15.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) Coiled-coil_56 PF09813.9 GAM21591.1 - 0.062 13.4 0.1 0.071 13.2 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Brix PF04427.18 GAM21592.1 - 3.9e-43 147.8 0.1 6.3e-43 147.1 0.1 1.3 1 0 0 1 1 1 1 Brix domain RNA_pol_Rpc4 PF05132.14 GAM21594.1 - 9.3 6.7 9.1 3.1 8.2 3.7 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 7tm_3 PF00003.22 GAM21595.1 - 2.4e-37 128.9 22.9 4.7e-37 128.0 22.9 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 GAM21595.1 - 8.2e-19 67.7 0.0 1.1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like CLASP_N PF12348.8 GAM21596.1 - 1.6e-36 126.0 6.9 1.6e-36 126.0 6.9 1.8 2 0 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 GAM21596.1 - 4.8e-05 23.9 3.9 0.046 14.3 0.0 4.4 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region NPR2 PF06218.11 GAM21598.1 - 1e-91 307.9 12.3 3.2e-75 253.6 12.4 2.9 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.13 GAM21598.1 - 7.8e-05 21.7 0.4 0.061 12.1 0.1 3.0 3 0 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Afi1 PF07792.12 GAM21598.1 - 0.0037 17.8 0.0 0.0084 16.6 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2250 PF10007.9 GAM21598.1 - 0.15 12.2 0.1 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_47 PF16221.5 GAM21598.1 - 0.18 11.4 0.1 0.73 9.4 0.0 2.0 2 0 0 2 2 2 0 winged helix-turn-helix SAP PF02037.27 GAM21600.1 - 1.9e-06 27.5 0.1 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 SAP domain TFIIA PF03153.13 GAM21600.1 - 0.00073 19.7 12.3 0.0013 18.9 12.3 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 GAM21600.1 - 0.01 15.3 14.1 0.014 14.7 14.1 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 GAM21600.1 - 0.019 13.3 9.4 0.024 12.9 9.4 1.2 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 GAM21600.1 - 0.072 12.9 9.8 0.24 11.2 9.8 1.9 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.16 GAM21600.1 - 0.096 11.9 2.7 0.23 10.7 2.7 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 GAM21600.1 - 0.11 10.8 8.9 0.15 10.4 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CNDH2_C PF16858.5 GAM21600.1 - 0.46 10.3 7.1 0.8 9.5 7.1 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4666 PF15697.5 GAM21600.1 - 1 10.0 4.9 0.38 11.5 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Cwf_Cwc_15 PF04889.12 GAM21600.1 - 2.8 7.6 14.2 6 6.5 14.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CUE PF02845.16 GAM21601.1 - 0.021 14.6 0.6 2.1 8.2 0.1 4.1 3 2 0 3 3 3 0 CUE domain DUF2951 PF11166.8 GAM21601.1 - 2.6 8.3 9.8 11 6.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) CSRNP_N PF16019.5 GAM21602.1 - 0.011 15.6 8.2 0.015 15.2 8.2 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF4746 PF15928.5 GAM21602.1 - 0.025 14.0 6.8 0.03 13.7 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ycf1 PF05758.12 GAM21602.1 - 0.038 11.9 2.0 0.043 11.7 2.0 1.0 1 0 0 1 1 1 0 Ycf1 MCRS_N PF13325.6 GAM21602.1 - 0.04 13.9 8.4 0.05 13.6 8.4 1.2 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Spt20 PF12090.8 GAM21602.1 - 0.041 13.5 10.8 0.049 13.2 10.8 1.2 1 0 0 1 1 1 0 Spt20 family DUF4820 PF16091.5 GAM21602.1 - 0.072 12.5 3.8 0.083 12.3 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) V_ATPase_I PF01496.19 GAM21602.1 - 0.4 8.5 7.6 0.43 8.4 7.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cob_adeno_trans PF01923.18 GAM21602.1 - 0.48 10.5 4.2 0.65 10.1 4.2 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase CLN3 PF02487.17 GAM21602.1 - 0.73 8.8 2.7 0.84 8.6 2.7 1.1 1 0 0 1 1 1 0 CLN3 protein Serinc PF03348.15 GAM21602.1 - 0.74 8.7 2.3 0.82 8.5 2.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4834 PF16118.5 GAM21602.1 - 0.88 10.6 4.5 1.4 9.9 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FAM222A PF15258.6 GAM21602.1 - 1 8.4 9.4 1.1 8.3 9.4 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Androgen_recep PF02166.16 GAM21602.1 - 1.1 8.1 9.5 1.3 7.8 9.5 1.1 1 0 0 1 1 1 0 Androgen receptor FAM176 PF14851.6 GAM21602.1 - 2.2 7.9 6.2 3.8 7.2 6.2 1.4 1 0 0 1 1 1 0 FAM176 family Zip PF02535.22 GAM21602.1 - 7.4 5.7 5.8 8.1 5.6 5.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 GAM21602.1 - 8.9 5.0 7.3 10 4.8 7.3 1.0 1 0 0 1 1 1 0 Presenilin Mon2_C PF16206.5 GAM21603.1 - 5.9e-75 252.9 8.6 6.7e-43 146.9 0.1 3.8 3 2 0 3 3 3 2 C-terminal region of Mon2 protein DCB PF16213.5 GAM21603.1 - 6.2e-57 192.1 6.8 6.2e-57 192.1 6.8 5.1 5 1 1 6 6 6 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 GAM21603.1 - 1.9e-37 128.6 1.1 1.9e-37 128.6 1.1 5.7 6 2 1 7 7 7 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAM21603.1 - 6.1e-12 45.2 0.5 6.1e-12 45.2 0.5 5.4 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Membr_traf_MHD PF10540.9 GAM21603.1 - 7.5 6.7 11.2 0.42 10.8 0.8 3.6 3 1 0 3 3 3 0 Munc13 (mammalian uncoordinated) homology domain Calreticulin PF00262.18 GAM21604.1 - 4.7e-120 400.8 1.6 5.7e-120 400.5 1.6 1.1 1 0 0 1 1 1 1 Calreticulin family LMBR1 PF04791.16 GAM21605.1 - 6.6e-129 431.1 16.7 7.9e-129 430.8 16.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein TMF_TATA_bd PF12325.8 GAM21605.1 - 0.004 17.4 0.1 0.0076 16.5 0.1 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.6 GAM21605.1 - 0.025 15.0 2.4 0.044 14.2 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2788 PF10981.8 GAM21605.1 - 7.2 6.7 9.8 20 5.3 2.8 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2788) LRR_8 PF13855.6 GAM21606.1 - 4.7e-45 151.2 63.1 1.5e-09 37.4 1.3 9.4 4 3 6 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 GAM21606.1 - 1.3e-44 149.4 73.0 2.5e-07 30.9 2.1 11.5 3 2 8 14 14 14 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM21606.1 - 4e-14 51.0 53.5 2 9.3 0.0 17.1 16 3 1 17 17 17 5 Leucine Rich Repeat LRR_9 PF14580.6 GAM21606.1 - 0.004 16.7 30.5 0.29 10.6 0.7 4.9 1 1 3 5 5 5 4 Leucine-rich repeat RsmF_methylt_CI PF17126.5 GAM21606.1 - 0.033 14.2 0.2 15 5.7 0.0 5.0 3 1 1 5 5 5 0 RsmF rRNA methyltransferase first C-terminal domain CheY-binding PF09078.11 GAM21606.1 - 0.19 11.9 5.3 0.9 9.7 0.0 4.4 5 0 0 5 5 5 0 CheY binding LRR_5 PF13306.6 GAM21606.1 - 1.4 8.9 5.8 3.2 7.7 0.3 3.2 2 2 2 4 4 4 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 GAM21606.1 - 4.6 7.5 68.4 1.2 9.4 0.1 14.6 17 0 0 17 17 17 0 Leucine Rich repeat GST_C_3 PF14497.6 GAM21607.1 - 3e-22 78.7 0.3 5.4e-22 77.9 0.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM21607.1 - 3.9e-09 36.7 0.0 1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM21607.1 - 1.1e-06 28.7 0.1 1.7e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM21607.1 - 0.00026 21.0 0.2 0.00068 19.6 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM21607.1 - 0.00069 20.0 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 GAM21607.1 - 0.0034 18.1 0.0 0.0063 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GAM21607.1 - 0.054 13.3 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 GAM21607.1 - 0.08 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein HMGL-like PF00682.19 GAM21608.1 - 1.7e-58 198.3 0.0 2e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Molydop_binding PF01568.21 GAM21608.1 - 0.013 15.6 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Androgen_recep PF02166.16 GAM21609.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Androgen receptor DUF3185 PF11381.8 GAM21610.1 - 0.41 10.7 2.8 8.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Myotub-related PF06602.14 GAM21611.1 - 5.9e-07 28.7 6.1 0.00017 20.6 6.1 2.9 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 GAM21611.1 - 8.9e-05 22.6 0.0 0.00045 20.3 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family Oxysterol_BP PF01237.18 GAM21612.1 - 4.5e-51 173.8 1.1 4.4e-46 157.4 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DUF5383 PF17355.2 GAM21612.1 - 0.35 11.3 2.8 29 5.0 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5383) zf-C3HC4_3 PF13920.6 GAM21613.1 - 5.4e-08 32.6 12.5 7.9e-08 32.0 12.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PMSI1 PF15322.6 GAM21613.1 - 0.0047 16.4 1.7 0.0078 15.7 1.7 1.3 1 0 0 1 1 1 1 Protein missing in infertile sperm 1, putative zf-RING_4 PF14570.6 GAM21613.1 - 0.0066 16.2 9.5 0.014 15.2 9.5 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 GAM21613.1 - 0.0087 16.4 15.1 0.014 15.7 15.1 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAM21613.1 - 0.01 15.7 14.2 0.018 14.9 14.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAM21613.1 - 0.01 15.8 12.2 0.02 14.8 12.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain SpoIIIAH PF12685.7 GAM21613.1 - 0.017 15.0 1.9 0.023 14.5 1.9 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein zf-C3HC4 PF00097.25 GAM21613.1 - 0.021 14.7 14.3 0.037 13.9 14.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sporozoite_P67 PF05642.11 GAM21613.1 - 0.021 12.9 1.0 0.027 12.6 1.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.12 GAM21613.1 - 0.039 12.0 2.8 0.049 11.6 2.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-ANAPC11 PF12861.7 GAM21613.1 - 0.16 12.0 5.6 7.7 6.6 5.1 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 GAM21613.1 - 0.31 10.9 13.8 0.56 10.1 13.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM21613.1 - 1.4 9.0 9.9 4.6 7.4 9.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger FNIP PF05725.12 GAM21615.1 - 3.9e-55 183.8 25.8 2.2e-16 59.7 0.3 7.0 4 2 1 7 7 7 6 FNIP Repeat F-box-like PF12937.7 GAM21615.1 - 0.1 12.5 0.9 0.82 9.6 0.2 2.7 2 0 0 2 2 2 0 F-box-like DHR-2 PF06920.13 GAM21616.1 - 9.7e-101 338.0 1.1 9.7e-101 338.0 1.1 1.7 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 GAM21616.1 - 9.4e-25 87.6 0.2 2.3e-24 86.3 0.2 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 GAM21616.1 - 1.3e-11 44.1 3.2 5.5e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 DOCK N-terminus SH3_2 PF07653.17 GAM21616.1 - 0.00034 20.2 0.1 0.0041 16.8 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 GAM21616.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.9 1 0 0 1 1 1 0 Variant SH3 domain C2 PF00168.30 GAM21616.1 - 0.077 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 C2 domain SH3_1 PF00018.28 GAM21616.1 - 0.16 11.6 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 SH3 domain TFIIA PF03153.13 GAM21616.1 - 6.3 6.7 29.1 12 5.8 29.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_2 PF13923.6 GAM21617.1 - 2.4e-11 43.3 10.4 3.7e-11 42.7 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM21617.1 - 4.1e-11 42.6 9.8 6.3e-11 42.0 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM21617.1 - 1.4e-10 40.8 6.7 2.2e-10 40.2 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM21617.1 - 2.9e-10 40.3 11.6 4.4e-10 39.7 11.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAM21617.1 - 5.4e-10 39.1 9.1 7.8e-10 38.6 9.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM21617.1 - 5.3e-09 36.0 5.7 5.3e-09 36.0 5.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAM21617.1 - 8.4e-08 32.2 11.1 1.4e-07 31.5 11.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAM21617.1 - 2.8e-06 27.1 9.0 5.4e-06 26.2 9.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAM21617.1 - 1.1e-05 25.6 8.3 2e-05 24.8 8.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 GAM21617.1 - 5.4e-05 22.9 3.9 0.0001 22.0 3.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 GAM21617.1 - 0.00019 21.4 4.3 0.00031 20.7 4.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 GAM21617.1 - 0.00027 20.8 2.7 0.00053 19.8 2.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.11 GAM21617.1 - 0.0013 18.6 1.8 0.0019 18.2 1.8 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 GAM21617.1 - 0.0026 17.1 1.1 0.0037 16.7 0.8 1.4 1 1 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.15 GAM21617.1 - 0.0053 16.9 0.1 0.018 15.2 0.0 1.9 2 0 0 2 2 1 1 U-box domain zf-UDP PF14569.6 GAM21617.1 - 0.023 14.8 2.9 0.067 13.3 2.9 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-P11 PF03854.14 GAM21617.1 - 0.066 12.9 5.2 0.11 12.2 5.2 1.3 1 0 0 1 1 1 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 GAM21617.1 - 0.078 12.6 7.5 0.13 11.9 7.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type EVI2A PF05399.11 GAM21617.1 - 0.089 12.4 2.0 0.12 12.0 2.0 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) zf-RING_4 PF14570.6 GAM21617.1 - 0.16 11.8 7.7 0.53 10.1 7.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 GAM21617.1 - 0.47 10.3 10.0 0.24 11.1 5.9 2.2 2 0 0 2 2 2 0 RING-like zinc finger DUF2946 PF11162.8 GAM21617.1 - 0.52 11.0 3.3 9.1 7.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) zf-RING_10 PF16685.5 GAM21617.1 - 0.55 10.4 4.9 0.88 9.8 4.9 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Sporozoite_P67 PF05642.11 GAM21617.1 - 1.6 6.7 6.4 2.1 6.3 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.9 GAM21617.1 - 1.8 8.1 12.5 2.6 7.6 12.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IBR PF01485.21 GAM21617.1 - 7.7 6.8 11.3 6.9 7.0 9.2 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain RasGEF PF00617.19 GAM21618.1 - 1.5e-48 165.4 1.4 1.5e-48 165.4 1.4 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM21618.1 - 8.3e-13 48.5 3.2 2.1e-12 47.2 1.2 2.7 2 0 0 2 2 2 1 RasGEF N-terminal motif SAC3_GANP PF03399.16 GAM21618.1 - 0.0036 16.7 0.4 0.17 11.2 0.4 2.7 2 1 1 3 3 3 1 SAC3/GANP family LisH_TPL PF17814.1 GAM21618.1 - 0.0038 16.9 1.0 0.009 15.6 1.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain TFIIE_beta PF02186.15 GAM21618.1 - 0.096 13.0 2.3 0.19 12.0 0.1 2.7 3 0 0 3 3 3 0 TFIIE beta subunit core domain Phospholip_B PF04916.13 GAM21619.1 - 1.6e-175 584.7 17.1 1.9e-175 584.5 17.1 1.0 1 0 0 1 1 1 1 Phospholipase B Haem_oxygenas_2 PF14518.6 GAM21620.1 - 7.3e-32 110.6 0.1 9.3e-32 110.2 0.1 1.1 1 0 0 1 1 1 1 Iron-containing redox enzyme TENA_THI-4 PF03070.16 GAM21620.1 - 7.3e-26 91.3 0.4 8.4e-26 91.1 0.4 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family DUF3050 PF11251.8 GAM21620.1 - 0.0034 17.1 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Leader_Erm PF08253.11 GAM21621.1 - 0.011 15.9 0.1 0.025 14.7 0.1 1.7 1 0 0 1 1 1 0 Erm Leader peptide Oxysterol_BP PF01237.18 GAM21622.1 - 5.1e-45 153.9 3.1 1.7e-40 139.0 0.1 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Phage_tube PF04985.14 GAM21622.1 - 0.039 13.6 0.1 0.076 12.7 0.1 1.4 1 0 0 1 1 1 0 Phage tail tube protein FII bMG10 PF17973.1 GAM21623.1 - 1e-21 77.4 0.0 4.5e-21 75.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial Alpha-2-macroglobulin MG10 domain MG2 PF01835.19 GAM21623.1 - 1.8e-08 34.7 0.0 4e-07 30.4 0.0 2.9 2 0 0 2 2 2 1 MG2 domain A2M PF00207.22 GAM21623.1 - 2.2e-08 33.8 0.1 1.4e-07 31.3 0.1 2.5 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 GAM21623.1 - 0.00024 21.4 1.2 0.0086 16.4 0.0 3.8 4 0 0 4 4 4 1 Alpha-2-macroglobulin bait region domain bMG3 PF11974.8 GAM21623.1 - 0.00039 20.4 0.2 0.0017 18.4 0.1 2.2 2 0 0 2 2 2 1 Bacterial alpha-2-macroglobulin MG3 domain DUF824 PF05688.11 GAM21623.1 - 0.18 11.6 1.3 1.2 9.0 0.3 2.9 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) DUF829 PF05705.14 GAM21624.1 - 2e-17 63.9 0.0 3.3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) RMP PF14996.6 GAM21624.1 - 0.21 11.8 3.0 0.33 11.2 3.0 1.2 1 0 0 1 1 1 0 Retinal Maintenance DUF829 PF05705.14 GAM21625.1 - 6e-16 59.1 0.4 6.9e-16 58.9 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) PP2C PF00481.21 GAM21626.1 - 1.4e-61 208.4 0.0 2.2e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 GAM21626.1 - 3e-41 139.0 55.2 5.8e-10 38.8 2.1 9.3 6 3 4 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 GAM21626.1 - 7.5e-36 121.6 58.6 1.6e-06 28.4 0.2 11.3 6 3 3 11 11 11 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM21626.1 - 2.9e-05 24.0 48.0 25 5.9 0.2 14.6 14 2 2 16 16 16 0 Leucine Rich Repeat PP2C_2 PF13672.6 GAM21626.1 - 3.4e-05 23.6 0.0 5.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAM21626.1 - 0.036 14.0 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF3557 PF12078.8 GAM21626.1 - 0.066 13.2 0.2 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3557) LRR_9 PF14580.6 GAM21626.1 - 0.17 11.4 21.3 1 8.8 1.2 5.5 2 2 3 6 6 6 0 Leucine-rich repeat LRR_6 PF13516.6 GAM21626.1 - 3.4 8.0 52.1 2.2 8.5 1.8 12.3 14 0 0 14 14 14 0 Leucine Rich repeat AhpC-TSA_2 PF13911.6 GAM21627.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme EGF_2 PF07974.13 GAM21628.1 - 0.001 19.4 40.7 0.008 16.5 13.7 3.0 3 0 0 3 3 3 2 EGF-like domain EGF PF00008.27 GAM21628.1 - 0.029 14.7 11.2 0.029 14.7 11.2 2.9 2 1 0 2 2 2 0 EGF-like domain hEGF PF12661.7 GAM21628.1 - 0.073 13.7 10.7 0.073 13.7 10.7 3.3 3 0 0 3 3 3 0 Human growth factor-like EGF 7tm_2 PF00002.24 GAM21629.1 - 2.1e-07 30.5 16.1 3.5e-07 29.8 16.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 GAM21629.1 - 3.1e-07 29.8 19.1 5.2e-07 29.0 19.1 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 GAM21629.1 - 0.16 12.6 1.7 0.23 12.1 0.6 1.8 2 0 0 2 2 2 0 Fz domain MFS_1 PF07690.16 GAM21630.1 - 1.1e-18 67.4 21.8 1.5e-18 66.9 21.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4834 PF16118.5 GAM21630.1 - 0.49 11.4 3.1 3.7 8.6 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Tmemb_9 PF05434.11 GAM21630.1 - 0.51 10.2 3.8 2.2 8.2 0.0 2.8 2 1 0 2 2 2 0 TMEM9 MFS_1 PF07690.16 GAM21631.1 - 1.6e-07 30.6 29.1 1.6e-07 30.6 29.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4428 PF14471.6 GAM21631.1 - 1.6 8.7 5.7 0.52 10.3 2.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) CLU PF13236.6 GAM21633.1 - 1.4e-52 178.8 0.0 2.9e-52 177.7 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAM21633.1 - 1.3e-10 41.6 1.4 3.1e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 LRR_4 PF12799.7 GAM21633.1 - 0.097 13.1 18.4 4.4 7.9 0.1 7.0 7 1 0 7 7 7 0 Leucine Rich repeats (2 copies) LZ3wCH PF18517.1 GAM21634.1 - 1.5e-12 47.4 1.3 5.1e-12 45.7 1.3 2.0 1 0 0 1 1 1 1 Leucine zipper with capping helix domain TBPIP PF07106.13 GAM21634.1 - 1.3e-09 37.8 0.0 3.2e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain CENP-F_leu_zip PF10473.9 GAM21634.1 - 0.0027 17.7 6.9 0.0027 17.7 6.9 1.7 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 GAM21634.1 - 0.0072 16.6 1.4 0.018 15.4 1.4 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF4407 PF14362.6 GAM21634.1 - 0.025 13.9 4.1 0.033 13.5 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bul1_C PF04426.12 GAM21634.1 - 0.035 13.5 3.4 0.048 13.1 3.4 1.1 1 0 0 1 1 1 0 Bul1 C terminus Sec34 PF04136.15 GAM21634.1 - 0.036 14.0 2.8 0.063 13.2 2.8 1.4 1 1 0 1 1 1 0 Sec34-like family DUF1664 PF07889.12 GAM21634.1 - 0.041 13.9 1.9 0.044 13.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-Q PF13094.6 GAM21634.1 - 0.059 13.6 13.1 0.94 9.7 13.1 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.8 GAM21634.1 - 0.094 12.8 12.4 0.1 12.7 3.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.11 GAM21634.1 - 0.1 12.9 8.3 0.34 11.2 8.3 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 SlyX PF04102.12 GAM21634.1 - 0.11 13.1 3.2 0.41 11.3 3.1 2.0 1 1 0 1 1 1 0 SlyX LMBR1 PF04791.16 GAM21634.1 - 0.25 10.2 6.0 0.33 9.8 6.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TolA_bind_tri PF16331.5 GAM21634.1 - 0.26 11.4 7.4 0.091 12.9 3.7 2.2 2 1 0 2 2 2 0 TolA binding protein trimerisation YabA PF06156.13 GAM21634.1 - 0.3 11.8 6.0 1.1 10.0 6.0 2.1 1 1 0 1 1 1 0 Initiation control protein YabA AAA_13 PF13166.6 GAM21634.1 - 0.43 9.2 9.1 0.026 13.2 1.0 2.0 1 1 1 2 2 2 0 AAA domain Jnk-SapK_ap_N PF09744.9 GAM21634.1 - 0.66 10.2 9.2 0.79 9.9 8.4 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 GAM21634.1 - 0.72 10.4 15.4 0.23 12.0 9.6 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region LPP PF04728.13 GAM21634.1 - 0.75 10.2 5.8 0.8 10.1 0.7 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Syntaxin-6_N PF09177.11 GAM21634.1 - 1.2 9.8 7.5 1.6 9.3 5.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.22 GAM21634.1 - 1.7 8.9 12.9 0.54 10.5 2.2 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 GAM21634.1 - 1.9 7.7 3.6 2.6 7.2 3.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein Cnn_1N PF07989.11 GAM21634.1 - 2 8.6 8.3 0.31 11.2 1.9 2.4 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 GAM21634.1 - 2.3 8.3 14.4 90 3.1 14.4 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4337 PF14235.6 GAM21634.1 - 2.5 8.2 6.3 0.46 10.6 0.7 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4337) DivIC PF04977.15 GAM21634.1 - 8 6.3 10.0 0.42 10.4 2.7 2.5 2 1 0 2 2 2 0 Septum formation initiator DUF4315 PF14193.6 GAM21634.1 - 8.3 6.5 12.3 0.46 10.5 5.9 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4315) CCDC-167 PF15188.6 GAM21634.1 - 9.1 6.7 8.4 0.93 9.9 1.3 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 GTP_EFTU PF00009.27 GAM21635.1 - 1.1e-29 103.4 0.2 2.2e-29 102.4 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM21635.1 - 5.8e-08 32.8 0.0 1.7e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 GAM21635.1 - 9.7e-07 29.1 0.7 8.3e-06 26.1 0.1 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 SRPRB PF09439.10 GAM21635.1 - 9.5e-06 25.2 0.2 0.00062 19.2 0.2 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAM21635.1 - 0.0017 17.8 2.0 0.006 16.0 2.0 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 GAM21635.1 - 0.017 14.8 4.0 3.3 7.5 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DcpS PF05652.12 GAM21635.1 - 0.1 13.4 0.4 17 6.3 0.1 2.6 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal RIBIOP_C PF04950.12 GAM21635.1 - 0.14 11.6 1.1 6.9 6.0 0.0 3.2 4 0 0 4 4 4 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal SNAP PF14938.6 GAM21636.1 - 1.5e-18 67.2 9.7 2.2e-18 66.7 9.7 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 GAM21636.1 - 0.0043 17.3 5.1 0.014 15.7 1.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat GYF PF02213.16 GAM21637.1 - 1.2e-15 56.9 0.4 1.2e-15 56.9 0.4 2.6 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 GAM21637.1 - 0.011 15.5 1.2 0.076 12.8 0.1 3.0 3 0 0 3 3 3 0 GYF domain 2 PHM7_cyt PF14703.6 GAM21638.1 - 0.014 15.7 0.5 0.86 9.8 0.3 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 GAM21638.1 - 0.014 14.7 29.7 0.035 13.4 9.5 3.1 3 0 0 3 3 3 0 Calcium-dependent channel, 7TM region, putative phosphate MNSV_P7B PF06692.11 GAM21638.1 - 0.16 12.0 7.1 0.044 13.8 0.7 2.9 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein Glyco_hydro_25 PF01183.20 GAM21639.1 - 9e-12 45.5 0.0 1e-11 45.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 DUF1906 PF08924.11 GAM21639.1 - 0.00013 22.2 2.7 0.0006 20.0 2.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1906) Semialdhyde_dhC PF02774.18 GAM21640.1 - 1.3e-33 116.6 0.0 2.3e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 GAM21640.1 - 3.4e-29 101.7 0.1 6.4e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM21640.1 - 0.0025 18.0 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.20 GAM21640.1 - 0.003 17.1 0.1 0.0089 15.6 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.16 GAM21640.1 - 0.059 14.1 1.0 0.075 13.7 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_10 PF13460.6 GAM21640.1 - 0.077 12.9 0.1 0.17 11.8 0.1 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Esterase PF00756.20 GAM21641.1 - 4.5e-46 157.5 0.0 5.4e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 GAM21641.1 - 0.00021 20.3 0.1 0.36 9.7 0.0 3.1 3 1 0 3 3 3 2 Chlorophyllase enzyme Peptidase_S9 PF00326.21 GAM21641.1 - 0.0026 17.2 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 GAM21641.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 GAM21641.1 - 0.026 13.5 0.3 3.5 6.6 0.0 3.0 3 1 1 4 4 4 0 Chlorophyllase TACI-CRD2 PF09305.10 GAM21641.1 - 0.03 14.4 0.2 0.1 12.6 0.2 1.9 1 0 0 1 1 1 0 TACI, cysteine-rich domain Abhydrolase_2 PF02230.16 GAM21641.1 - 0.043 13.6 0.0 0.082 12.7 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Coiled PF05710.12 GAM21642.1 - 0.0022 18.8 4.2 0.0026 18.5 4.2 1.1 1 0 0 1 1 1 1 Coiled coil Glyco_tranf_2_2 PF10111.9 GAM21643.1 - 9e-09 35.2 0.0 2.2e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAM21643.1 - 1.4e-07 31.5 0.0 2.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.14 GAM21643.1 - 0.0013 18.4 0.1 0.0029 17.2 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.6 GAM21643.1 - 0.0013 18.6 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 TPR_11 PF13414.6 GAM21643.1 - 0.048 13.4 0.3 13 5.6 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 GAM21643.1 - 0.11 12.7 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat ADPRTs_Tse2 PF18648.1 GAM21643.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins LemA PF04011.12 GAM21643.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 LemA family Tfb5 PF06331.12 GAM21643.1 - 0.13 12.2 0.1 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 Sec16_N PF12935.7 GAM21644.1 - 0.018 15.2 5.5 0.026 14.7 5.5 1.1 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus Pex14_N PF04695.13 GAM21644.1 - 0.022 15.5 0.1 0.037 14.7 0.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 GAM21644.1 - 0.051 12.5 3.5 0.068 12.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF3464 PF11947.8 GAM21644.1 - 0.2 11.4 0.2 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 CYSTM PF12734.7 GAM21644.1 - 1.1 9.6 5.0 3.1 8.2 5.0 1.8 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF4834 PF16118.5 GAM21644.1 - 2 9.4 13.0 3.2 8.8 9.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) AATF-Che1 PF13339.6 GAM21645.1 - 9.2e-30 104.1 7.7 9.2e-30 104.1 7.7 3.8 4 1 0 4 4 4 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 GAM21645.1 - 5.2e-20 71.7 0.3 5.2e-20 71.7 0.3 4.0 5 0 0 5 5 5 2 Apoptosis-antagonizing transcription factor, C-terminal DEAD PF00270.29 GAM21646.1 - 3.4e-42 144.2 0.3 5.9e-42 143.4 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM21646.1 - 7.6e-29 100.3 0.6 2.4e-27 95.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM21646.1 - 1.2e-05 25.4 0.0 2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAM21646.1 - 0.004 16.5 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 GAM21646.1 - 0.0067 16.8 0.5 0.037 14.4 0.6 2.2 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 GAM21646.1 - 0.042 13.7 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Helicase AAA_30 PF13604.6 GAM21646.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fanconi_A PF03511.14 GAM21646.1 - 0.097 12.6 0.0 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 Fanconi anaemia group A protein zf-CCCH PF00642.24 GAM21647.1 - 2.2e-14 52.9 17.3 2.6e-07 30.4 2.0 4.0 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAM21647.1 - 2.7e-09 36.8 23.1 0.00051 20.0 6.6 4.1 3 1 0 3 3 3 3 Zinc finger domain Torus PF16131.5 GAM21647.1 - 4.7e-08 33.7 22.0 0.00058 20.5 1.8 4.1 2 1 1 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 GAM21647.1 - 8.4e-06 26.0 16.0 0.0046 17.1 9.8 2.6 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 GAM21647.1 - 0.0021 17.8 25.7 0.0074 16.1 0.4 4.4 4 1 0 4 4 4 2 CCCH-type zinc finger zf-C3H1 PF10650.9 GAM21647.1 - 0.45 10.3 17.5 0.68 9.7 0.5 4.0 4 1 0 4 4 4 0 Putative zinc-finger domain Membralin PF09746.9 GAM21647.1 - 1.6 7.7 5.4 0.44 9.5 0.7 2.0 2 0 0 2 2 2 0 Tumour-associated protein E1-E2_ATPase PF00122.20 GAM21648.1 - 1.1e-30 106.5 2.0 2e-30 105.6 0.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM21648.1 - 1.6e-18 67.8 0.1 4.7e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 GAM21648.1 - 7.7e-10 39.0 0.3 7.7e-10 39.0 0.3 2.5 3 1 0 3 3 3 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 GAM21648.1 - 0.00038 20.1 0.0 0.001 18.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM21648.1 - 0.011 15.5 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM21648.1 - 0.024 14.7 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) YorP PF09629.10 GAM21648.1 - 0.087 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 YorP protein FluMu_N PF17891.1 GAM21648.1 - 0.19 11.5 0.0 0.52 10.1 0.0 1.7 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain 2_5_RNA_ligase2 PF13563.6 GAM21649.1 - 9.2e-29 100.3 0.0 1.1e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 GAM21649.1 - 0.00056 20.0 0.0 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 LigT like Phosphoesterase RsmJ PF04378.13 GAM21649.1 - 0.041 13.1 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ GATA PF00320.27 GAM21650.1 - 2.7e-15 55.7 3.4 2.7e-15 55.7 3.4 1.7 2 0 0 2 2 2 1 GATA zinc finger Peroxin-13_N PF04088.13 GAM21650.1 - 3.7 7.8 9.5 2.1 8.6 1.1 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region UQ_con PF00179.26 GAM21651.1 - 1.1e-49 167.6 0.0 1.3e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM21651.1 - 0.00027 20.6 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAM21651.1 - 0.0058 16.9 0.1 0.0097 16.2 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 GAM21651.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain BRE PF06113.12 GAM21651.1 - 0.15 10.8 0.5 0.22 10.4 0.2 1.4 2 0 0 2 2 2 0 Brain and reproductive organ-expressed protein (BRE) TcfC PF16967.5 GAM21654.1 - 0.044 13.3 0.0 0.081 12.4 0.0 1.5 1 1 0 1 1 1 0 E-set like domain Y_Y_Y PF07495.13 GAM21654.1 - 0.073 13.0 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain DUF3464 PF11947.8 GAM21655.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 DHHC PF01529.20 GAM21655.1 - 0.77 9.9 6.6 2.2 8.4 6.5 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase Mito_carr PF00153.27 GAM21656.1 - 7.2e-65 215.0 4.6 7.2e-22 77.1 0.1 3.4 4 0 0 4 4 4 3 Mitochondrial carrier protein COG6 PF06419.11 GAM21657.1 - 7.2e-133 444.0 10.1 1.8e-122 409.7 2.6 2.0 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 Exo70 PF03081.15 GAM21657.1 - 0.006 15.7 0.1 0.006 15.7 0.1 2.8 2 1 2 4 4 4 1 Exo70 exocyst complex subunit Telomere_reg-2 PF10193.9 GAM21657.1 - 0.0068 16.8 0.1 0.027 14.9 0.1 2.0 1 0 0 1 1 1 1 Telomere length regulation protein Ank_2 PF12796.7 GAM21658.1 - 4e-06 27.3 0.0 0.00041 20.9 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM21658.1 - 9.9e-05 22.5 2.2 5.1 8.0 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 GAM21658.1 - 0.0019 18.8 2.3 20 5.9 0.0 4.9 4 2 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM21658.1 - 0.0071 16.8 2.8 1.8 9.1 1.2 4.2 3 1 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 GAM21658.1 - 0.0087 16.4 0.8 1.1e+02 3.2 0.0 4.6 4 1 1 5 5 5 0 Ankyrin repeats (many copies) UBA PF00627.31 GAM21658.1 - 0.19 11.7 0.1 22 5.1 0.0 2.6 2 0 0 2 2 2 0 UBA/TS-N domain MIP PF00230.20 GAM21659.1 - 1.2e-30 106.9 12.0 1.7e-30 106.4 12.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF5362 PF17319.2 GAM21659.1 - 0.41 10.5 5.2 0.25 11.2 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5362) PEPcase PF00311.17 GAM21660.1 - 1.2e-283 943.1 0.0 1.7e-283 942.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 GAM21660.1 - 9.3e-05 21.1 0.0 0.0043 15.6 0.0 2.5 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxylase Guanylate_cyc PF00211.20 GAM21661.1 - 1.6e-85 285.3 1.4 2e-44 151.4 1.3 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 GAM21661.1 - 7.7e-06 25.5 6.1 0.0018 17.7 0.1 2.8 3 0 0 3 3 3 2 Heme NO binding associated RRM_1 PF00076.22 GAM21662.1 - 9.1e-54 179.2 2.8 9.4e-20 70.2 0.2 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM21662.1 - 2.5e-08 33.9 0.4 0.0021 18.2 0.0 4.1 3 1 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 GAM21662.1 - 0.00037 20.8 3.0 2.5 8.3 0.0 4.6 3 2 2 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter BRAP2 PF07576.12 GAM21662.1 - 0.0004 20.6 0.1 2.9 8.2 0.0 3.2 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_5 PF13893.6 GAM21662.1 - 0.00051 19.6 0.2 2.8 7.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 GAM21662.1 - 0.00089 19.2 0.0 2.4 8.3 0.0 2.7 2 0 0 2 2 2 2 RNA binding domain SET_assoc PF11767.8 GAM21662.1 - 0.00096 18.8 0.1 0.084 12.5 0.0 3.0 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 GAM21662.1 - 0.0082 16.1 1.2 4.9 7.2 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 GAM21662.1 - 0.057 13.3 0.0 14 5.6 0.0 2.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif HAMP PF00672.25 GAM21662.1 - 0.13 12.7 0.0 16 6.0 0.0 2.4 2 0 0 2 2 2 0 HAMP domain Limkain-b1 PF11608.8 GAM21662.1 - 0.16 12.0 1.1 12 6.1 0.0 3.3 3 1 1 4 4 4 0 Limkain b1 SARAF PF06682.12 GAM21662.1 - 0.28 10.8 7.3 0.46 10.1 7.3 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis G8 PF10162.9 GAM21663.1 - 2.9e-24 85.5 0.0 6.2e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 GAM21663.1 - 8.4 6.2 12.8 13 5.6 0.3 4.2 3 2 0 3 3 3 0 Right handed beta helix region Vps26 PF03643.15 GAM21664.1 - 1.7e-47 161.7 0.2 2.2e-47 161.4 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 GAM21664.1 - 4.5e-07 30.0 0.2 2.8e-06 27.5 0.2 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Acyl_transf_3 PF01757.22 GAM21666.1 - 2.1e-23 82.9 34.9 2.1e-23 82.9 34.9 2.0 2 0 0 2 2 2 1 Acyltransferase family YibE_F PF07907.11 GAM21666.1 - 0.49 9.9 10.7 0.062 12.8 1.7 3.1 3 0 0 3 3 3 0 YibE/F-like protein Chal_sti_synt_C PF02797.15 GAM21667.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain UBX PF00789.20 GAM21668.1 - 1.4e-14 54.0 0.1 4.7e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 UBX domain Zip PF02535.22 GAM21668.1 - 0.072 12.3 0.1 0.097 11.9 0.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter O-antigen_lig PF13425.6 GAM21668.1 - 0.27 10.0 2.1 0.32 9.7 2.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YMF19 PF02326.15 GAM21668.1 - 0.81 10.5 6.0 1.5 9.7 3.7 2.3 1 1 1 2 2 2 0 Plant ATP synthase F0 DUF543 PF04418.12 GAM21669.1 - 1.5e-05 24.9 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Patatin PF01734.22 GAM21670.1 - 2.4e-23 83.4 0.1 5.7e-23 82.2 0.1 1.6 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3050 PF11251.8 GAM21670.1 - 0.11 12.1 0.4 0.19 11.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) ADH_zinc_N PF00107.26 GAM21671.1 - 5.5e-11 42.6 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 GAM21671.1 - 0.052 13.4 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding SnoaL_2 PF12680.7 GAM21672.1 - 0.00093 19.8 0.0 0.0012 19.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain RhoGAP PF00620.27 GAM21673.1 - 2.5e-26 92.3 0.1 5.8e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 GAM21673.1 - 3.8e-13 49.5 0.0 5.7e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family tRNA_synthFbeta PF17759.1 GAM21674.1 - 2.9e-43 147.8 0.0 3.9e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 GAM21674.1 - 3.8e-32 110.4 0.1 5.2e-31 106.7 0.0 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 GAM21674.1 - 5.9e-24 84.7 0.1 1.1e-23 83.8 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 GAM21674.1 - 1.3e-19 70.3 0.0 1.4e-16 60.5 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain MIF4G PF02854.19 GAM21674.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 MIF4G domain Chromate_transp PF02417.15 GAM21675.1 - 8.7e-17 61.7 12.9 8.7e-17 61.7 12.9 2.3 2 0 0 2 2 2 2 Chromate transporter Xpo1 PF08389.12 GAM21676.1 - 3.9e-22 78.9 1.7 3.9e-22 78.9 1.7 3.9 3 0 0 3 3 3 1 Exportin 1-like protein Glyoxalase_2 PF12681.7 GAM21676.1 - 0.036 14.0 0.2 0.16 11.9 0.2 2.1 1 0 0 1 1 1 0 Glyoxalase-like domain DUF1981 PF09324.10 GAM21676.1 - 3.1 7.7 13.7 8.4 6.3 0.1 5.4 5 1 1 6 6 6 0 Domain of unknown function (DUF1981) EDS1_EP PF18117.1 GAM21678.1 - 0.037 14.5 0.0 0.2 12.2 0.0 2.2 2 0 0 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain PYST-C1 PF09690.10 GAM21679.1 - 2 8.2 7.4 18 5.2 0.2 2.9 2 0 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) SIS PF01380.22 GAM21681.1 - 6.4e-15 55.2 0.1 4.1e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.6 GAM21681.1 - 1e-06 28.8 0.1 0.026 14.6 0.0 3.2 2 1 1 3 3 3 2 SIS domain EMG1 PF03587.14 GAM21681.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase DUF4834 PF16118.5 GAM21682.1 - 0.00077 20.4 0.2 0.0019 19.1 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) CRA PF06589.11 GAM21682.1 - 0.015 15.4 0.8 2.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) SID-1_RNA_chan PF13965.6 GAM21682.1 - 0.021 13.3 0.3 0.033 12.6 0.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1325 PF07039.11 GAM21683.1 - 1.1e-31 109.7 0.7 1.1e-31 109.7 0.7 1.6 2 0 0 2 2 2 1 SGF29 tudor-like domain Tudor_3 PF18115.1 GAM21683.1 - 1.3e-06 28.1 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Sporozoite_P67 PF05642.11 GAM21683.1 - 2.1e-05 22.8 11.6 3.1e-05 22.3 11.6 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF3498 PF12004.8 GAM21683.1 - 0.0015 17.9 12.5 0.0018 17.6 12.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) DUF966 PF06136.13 GAM21683.1 - 0.0038 17.0 12.1 0.0051 16.6 12.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF966) FAP206 PF12018.8 GAM21683.1 - 0.041 13.4 0.3 0.086 12.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function SOG2 PF10428.9 GAM21683.1 - 0.091 11.9 20.0 0.11 11.7 20.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Draxin PF15550.6 GAM21683.1 - 0.49 10.2 8.0 0.87 9.4 8.0 1.4 1 0 0 1 1 1 0 Draxin Apt1 PF10351.9 GAM21683.1 - 1.9 7.2 12.7 2.5 6.8 12.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.13 GAM21683.1 - 2 8.0 14.6 0.64 9.6 11.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) Raftlin PF15250.6 GAM21683.1 - 4.1 6.0 11.6 7 5.3 11.6 1.5 1 1 0 1 1 1 0 Raftlin GREB1 PF15782.5 GAM21683.1 - 9.1 3.3 11.1 10 3.1 11.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pneumo_att_G PF05539.11 GAM21683.1 - 9.8 5.7 28.0 14 5.2 28.0 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Methyltransf_11 PF08241.12 GAM21684.1 - 5.5e-09 36.6 0.1 1.6e-07 31.8 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 GAM21684.1 - 4e-08 33.0 0.1 9.4e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAM21684.1 - 8.4e-08 32.8 0.0 6.1e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 GAM21684.1 - 6.6e-06 26.1 0.0 9.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.14 GAM21684.1 - 2.2e-05 24.1 0.0 4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 GAM21684.1 - 0.00015 21.7 0.1 0.00054 19.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM21684.1 - 0.00028 21.6 0.0 0.00073 20.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM21684.1 - 0.00051 19.9 0.0 0.0014 18.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 GAM21684.1 - 0.00054 19.4 0.2 0.0012 18.3 0.1 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 GAM21684.1 - 0.0034 16.4 0.1 0.0054 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_31 PF13847.6 GAM21684.1 - 0.0088 15.9 0.0 0.024 14.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAM21684.1 - 0.012 15.3 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 GAM21684.1 - 0.037 13.8 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.13 GAM21684.1 - 0.056 13.8 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Rrp40_N PF18311.1 GAM21684.1 - 0.061 13.3 0.4 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 Exosome complex exonuclease Rrp40 N-terminal domain Methyltransf_32 PF13679.6 GAM21684.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 14-3-3 PF00244.20 GAM21685.1 - 8.7e-105 349.1 2.0 9.9e-105 348.9 2.0 1.0 1 0 0 1 1 1 1 14-3-3 protein Man-6-P_recep PF02157.15 GAM21686.1 - 1.7e-11 43.7 0.7 1.9e-11 43.5 0.7 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 GAM21686.1 - 2e-07 31.2 0.5 3e-07 30.6 0.5 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 PRKCSH_1 PF13015.6 GAM21686.1 - 1.7e-05 24.5 0.1 2.4e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein CIMR PF00878.18 GAM21686.1 - 0.00062 19.9 4.1 0.056 13.5 0.2 2.4 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Ank_2 PF12796.7 GAM21687.1 - 3.8e-22 78.7 1.6 1.4e-05 25.6 0.0 5.7 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM21687.1 - 4.4e-13 49.2 7.1 2 8.8 0.0 9.5 6 2 4 10 10 10 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM21687.1 - 1.8e-10 41.1 6.1 0.1 13.2 0.0 8.3 7 3 3 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM21687.1 - 3.7e-09 36.1 7.2 40 5.3 0.0 9.7 10 1 1 11 11 11 0 Ankyrin repeat DUF3447 PF11929.8 GAM21687.1 - 5e-08 32.8 6.6 0.0018 18.2 0.2 5.7 4 3 1 5 5 5 2 Domain of unknown function (DUF3447) Ank PF00023.30 GAM21687.1 - 0.076 13.5 1.9 2.7e+02 2.3 0.0 5.7 4 2 0 4 4 4 0 Ankyrin repeat Annexin PF00191.20 GAM21688.1 - 8.2e-82 269.3 4.2 4.5e-24 84.3 0.1 4.1 4 0 0 4 4 4 4 Annexin DUF5638 PF18688.1 GAM21688.1 - 0.12 12.7 0.8 3.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5638) Annexin PF00191.20 GAM21689.1 - 7.7e-75 246.9 2.2 4e-22 78.1 0.1 4.1 4 0 0 4 4 4 4 Annexin HEAT PF02985.22 GAM21690.1 - 7.6e-40 131.5 25.8 0.0047 17.1 0.1 21.8 23 0 0 23 23 20 9 HEAT repeat HEAT_EZ PF13513.6 GAM21690.1 - 1.2e-37 127.9 28.2 0.00034 21.0 0.0 18.6 18 2 2 20 20 19 10 HEAT-like repeat HEAT_2 PF13646.6 GAM21690.1 - 2.3e-29 101.6 14.0 0.00092 19.6 0.0 14.4 9 5 8 18 18 17 9 HEAT repeats Vac14_Fab1_bd PF12755.7 GAM21690.1 - 8.5e-20 71.2 0.0 5.3e-05 23.7 0.0 8.9 8 1 0 8 8 7 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAM21690.1 - 3.3e-14 53.2 7.6 0.097 12.7 0.0 10.5 10 1 0 11 11 11 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 GAM21690.1 - 3.5e-12 46.4 15.3 0.0015 18.2 0.0 8.1 9 0 0 9 9 9 3 CLASP N terminal IFRD PF05004.13 GAM21690.1 - 1.1e-09 37.9 19.0 4.6e-05 22.7 0.0 7.5 6 4 0 6 6 6 2 Interferon-related developmental regulator (IFRD) NUC173 PF08161.12 GAM21690.1 - 0.00063 19.5 0.5 1.8 8.2 0.0 4.9 4 0 0 4 4 4 1 NUC173 domain ParcG PF10274.9 GAM21690.1 - 0.0014 18.8 18.5 16 5.5 0.1 9.5 7 3 4 11 11 10 0 Parkin co-regulated protein DUF3437 PF11919.8 GAM21690.1 - 0.036 14.0 1.4 5.4 7.0 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) DUF2019 PF09450.10 GAM21690.1 - 0.1 12.5 0.2 0.77 9.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) Arm PF00514.23 GAM21690.1 - 0.41 10.8 8.2 1.2e+02 2.9 0.0 7.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat eIF3_subunit PF08597.10 GAM21690.1 - 0.63 9.9 18.9 0.018 15.0 8.5 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CAF1 PF04857.20 GAM21690.1 - 0.8 8.8 3.4 1.9 7.6 3.4 1.6 1 0 0 1 1 1 0 CAF1 family ribonuclease RNA_pol_Rpc4 PF05132.14 GAM21690.1 - 9.1 6.7 7.7 1.1e+02 3.2 0.0 2.8 3 0 0 3 3 3 0 RNA polymerase III RPC4 tRNA-synt_2c PF01411.19 GAM21692.1 - 1.5e-182 608.0 0.0 2e-182 607.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 GAM21692.1 - 1.5e-17 64.3 0.8 1.5e-17 64.3 0.8 2.3 2 0 0 2 2 2 1 DHHA1 domain tRNA_SAD PF07973.14 GAM21692.1 - 9.5e-15 54.4 0.0 2.7e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF3857 PF12969.7 GAM21692.1 - 0.094 12.8 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) Ras PF00071.22 GAM21693.1 - 1.7e-48 164.3 0.0 2.1e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM21693.1 - 6.6e-29 100.6 0.0 1.2e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM21693.1 - 2.7e-12 46.5 0.0 3.3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GAM21693.1 - 0.00043 19.5 0.3 0.73 8.9 0.0 2.9 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.22 GAM21693.1 - 0.0045 17.4 0.2 0.14 12.5 0.1 2.5 1 1 1 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 GAM21693.1 - 0.005 16.9 0.0 0.0077 16.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM21693.1 - 0.0051 16.4 0.0 0.014 15.0 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM21693.1 - 0.016 15.1 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 GAM21693.1 - 0.046 13.4 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 GAM21693.1 - 0.058 12.7 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TsaE PF02367.17 GAM21693.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 GAM21693.1 - 0.24 11.6 0.0 0.45 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_M22 PF00814.25 GAM21694.1 - 1.4e-77 261.1 0.0 1.6e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family HEAT_EZ PF13513.6 GAM21695.1 - 2.1e-17 63.3 0.0 0.001 19.6 0.0 8.4 8 0 0 8 8 8 3 HEAT-like repeat Importin_rep_4 PF18808.1 GAM21695.1 - 4.3e-12 46.1 8.6 1.5e-11 44.4 0.2 4.0 4 1 1 5 5 4 1 Importin repeat HEAT_2 PF13646.6 GAM21695.1 - 6.3e-11 42.5 0.0 0.00018 21.8 0.0 5.1 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 GAM21695.1 - 1.4e-08 34.3 3.0 0.0067 16.6 0.0 7.5 7 0 0 7 7 7 1 HEAT repeat RIX1 PF08167.12 GAM21695.1 - 6.4e-06 26.0 1.5 0.43 10.3 0.0 4.6 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 GAM21695.1 - 5.3e-05 22.5 17.2 0.04 13.0 0.1 4.6 4 1 0 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 GAM21695.1 - 5.5e-05 23.7 0.6 0.065 13.8 0.0 4.6 5 0 0 5 5 3 1 Vacuolar 14 Fab1-binding region ParcG PF10274.9 GAM21695.1 - 0.00014 22.0 2.5 7.2 6.7 0.2 5.3 3 2 1 5 5 5 1 Parkin co-regulated protein Cnd1 PF12717.7 GAM21695.1 - 0.00029 20.9 7.7 0.0012 18.9 0.0 4.9 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 GAM21695.1 - 0.00077 19.3 0.4 2.3 8.2 0.1 4.0 3 0 0 3 3 3 2 Importin-beta N-terminal domain DUF4042 PF13251.6 GAM21695.1 - 0.012 15.3 3.9 33 4.1 0.0 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) DUF3385 PF11865.8 GAM21695.1 - 0.014 15.3 12.0 1.2 9.0 0.0 5.5 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) Importin_rep_6 PF18829.1 GAM21695.1 - 0.041 14.0 4.4 0.073 13.2 1.8 2.8 2 0 0 2 2 2 0 Importin repeat 6 DUF1258 PF06869.12 GAM21695.1 - 0.061 12.8 0.2 1.5 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1258) VHS PF00790.19 GAM21695.1 - 0.26 11.2 4.1 6.8 6.5 0.0 3.8 4 0 0 4 4 4 0 VHS domain Tti2 PF10521.9 GAM21695.1 - 1.9 8.0 7.3 8.9 5.7 0.0 4.5 5 0 0 5 5 5 0 Tti2 family ABC_tran PF00005.27 GAM21696.1 - 6.9e-26 91.4 0.0 1.2e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAM21696.1 - 9.3e-21 74.3 28.1 1.3e-20 73.8 28.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAM21696.1 - 3.3e-13 50.1 0.1 2.4e-08 34.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAM21696.1 - 0.0068 16.2 0.0 0.5 10.0 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 GAM21696.1 - 0.014 14.8 0.0 0.46 9.9 0.0 2.0 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM21696.1 - 0.12 12.9 0.2 0.2 12.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 GAM21696.1 - 0.56 9.4 11.4 0.093 12.0 7.6 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 GAM21697.1 - 1.5e-33 116.4 35.3 2.4e-33 115.7 35.3 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 GAM21697.1 - 6.8e-26 91.4 0.0 1.3e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM21697.1 - 3.3e-08 33.7 0.4 3.1e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAM21697.1 - 7.1e-05 22.7 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM21697.1 - 0.054 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 GAM21697.1 - 0.088 12.4 0.1 0.26 10.9 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 GAM21698.1 - 1.6e-49 166.7 1.3 1e-23 83.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 GAM21698.1 - 2e-22 79.3 3.0 2.5e-22 79.0 1.5 2.0 2 0 0 2 2 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 GAM21698.1 - 2.2e-22 79.3 0.1 7.6e-10 38.5 0.1 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAM21698.1 - 1e-10 41.5 17.1 0.009 15.6 0.0 5.6 4 3 0 4 4 4 4 Elongation factor Tu GTP binding domain AIG1 PF04548.16 GAM21698.1 - 2.6e-10 40.0 0.6 0.00051 19.4 0.2 2.5 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 GAM21698.1 - 1.9e-09 37.8 25.3 0.00074 19.6 0.0 6.2 5 1 0 5 5 4 4 Dynamin family RsgA_GTPase PF03193.16 GAM21698.1 - 1e-08 35.3 1.6 0.016 15.1 0.0 4.1 4 0 0 4 4 4 2 RsgA GTPase Roc PF08477.13 GAM21698.1 - 1.1e-07 32.1 0.7 0.029 14.6 0.1 3.4 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM21698.1 - 5.2e-05 22.7 0.3 0.04 13.3 0.0 2.8 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.22 GAM21698.1 - 0.00014 21.5 0.5 0.23 11.1 0.2 2.9 2 1 0 2 2 2 2 Ras family AAA PF00004.29 GAM21698.1 - 0.00033 21.1 0.4 0.025 15.0 0.0 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM21698.1 - 0.00033 20.9 0.2 0.044 14.0 0.0 3.3 3 1 0 3 3 3 1 AAA domain Arf PF00025.21 GAM21698.1 - 0.0005 19.6 1.6 2.3 7.6 0.1 3.8 2 2 0 2 2 2 2 ADP-ribosylation factor family AAA_24 PF13479.6 GAM21698.1 - 0.00052 19.8 1.5 1.1 9.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 GAM21698.1 - 0.0024 18.3 0.7 0.31 11.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain Ploopntkinase3 PF18751.1 GAM21698.1 - 0.0048 16.8 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 cobW PF02492.19 GAM21698.1 - 0.0071 16.0 6.9 0.63 9.6 0.9 4.3 4 1 0 5 5 5 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 GAM21698.1 - 0.0084 16.5 0.0 2.4 8.6 0.0 3.2 2 0 0 2 2 2 1 RNA helicase MobB PF03205.14 GAM21698.1 - 0.019 14.9 1.0 9 6.2 0.0 3.4 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 GAM21698.1 - 0.035 13.9 0.1 7.8 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain TniB PF05621.11 GAM21698.1 - 0.036 13.5 0.1 6.5 6.1 0.0 2.7 3 0 0 3 3 3 0 Bacterial TniB protein MeaB PF03308.16 GAM21698.1 - 0.11 11.5 0.1 5.4 5.9 0.1 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 GAM21698.1 - 0.13 12.7 14.3 3.7 8.1 0.0 3.4 2 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 GAM21698.1 - 0.49 10.9 0.0 0.49 10.9 0.0 4.1 3 1 1 4 4 3 0 AAA domain PARP PF00644.20 GAM21699.1 - 1e-29 103.5 0.2 1e-28 100.3 0.2 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 GAM21699.1 - 1.2e-19 70.7 0.5 3.2e-19 69.4 0.5 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain BRCT_2 PF16589.5 GAM21699.1 - 7.3e-12 45.5 0.3 2e-11 44.2 0.3 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain WGR PF05406.15 GAM21699.1 - 1.4e-10 41.1 0.0 3.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 GAM21699.1 - 1.6e-10 41.2 0.7 3.8e-10 40.0 0.7 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ank_2 PF12796.7 GAM21699.1 - 2.2e-09 37.8 0.3 1.6e-06 28.6 0.4 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM21699.1 - 4.5e-08 33.5 0.1 2.5e-06 27.9 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM21699.1 - 1.2e-06 28.7 0.0 7.2e-06 26.2 0.1 2.4 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM21699.1 - 4.4e-06 26.6 0.2 7.2e-05 22.9 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAM21699.1 - 1.7e-05 25.0 0.2 9e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat LIG3_BRCT PF16759.5 GAM21699.1 - 7.5e-05 22.9 0.2 0.00019 21.6 0.2 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 GAM21699.1 - 0.00052 19.9 0.1 0.0018 18.2 0.1 1.9 2 0 0 2 2 2 1 twin BRCT domain Asp PF00026.23 GAM21700.1 - 1.7e-36 126.3 1.8 5.9e-25 88.3 0.0 3.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM21700.1 - 1.2e-16 61.5 0.3 2e-16 60.8 0.3 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAM21700.1 - 2.2e-13 50.3 0.0 4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal PTH2 PF01981.16 GAM21701.1 - 2.2e-44 150.5 0.5 3e-44 150.0 0.5 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 OSTbeta PF15048.6 GAM21701.1 - 0.0037 17.4 0.1 0.0049 17.0 0.1 1.4 1 1 0 1 1 1 1 Organic solute transporter subunit beta protein FAM176 PF14851.6 GAM21701.1 - 0.036 13.7 0.1 0.045 13.4 0.1 1.4 1 0 0 1 1 1 0 FAM176 family DUF4834 PF16118.5 GAM21701.1 - 0.12 13.3 0.2 0.21 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Asparaginase_2 PF01112.18 GAM21702.1 - 4.7e-118 393.7 4.1 5.4e-118 393.5 4.1 1.0 1 0 0 1 1 1 1 Asparaginase 2-oxoacid_dh PF00198.23 GAM21704.1 - 1.7e-81 273.1 0.1 2.5e-81 272.5 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAM21704.1 - 6e-20 70.9 0.4 1.1e-19 70.0 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAM21704.1 - 0.0028 17.4 0.3 1.1 9.1 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 GAM21704.1 - 0.095 11.9 0.0 0.51 9.5 0.0 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion eIF3_subunit PF08597.10 GAM21704.1 - 1.6 8.6 8.3 2.4 8.0 8.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DEAD PF00270.29 GAM21705.1 - 1.1e-49 168.5 0.0 2.9e-49 167.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM21705.1 - 1.7e-32 112.1 0.1 1.4e-30 105.9 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM21705.1 - 1.5e-05 25.1 0.8 0.00018 21.5 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HrpB2 PF09487.10 GAM21705.1 - 0.12 12.8 1.0 0.29 11.6 1.0 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) DnaJ_C PF01556.18 GAM21706.1 - 2e-39 135.0 0.4 2.9e-39 134.5 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAM21706.1 - 4e-25 87.7 2.1 6.9e-25 86.9 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAM21706.1 - 3e-12 46.7 19.5 5.8e-12 45.8 19.5 1.5 1 0 0 1 1 1 1 DnaJ central domain zf-RING_10 PF16685.5 GAM21706.1 - 0.04 14.1 0.6 0.04 14.1 0.6 1.9 1 1 1 2 2 2 0 zinc RING finger of MSL2 CDC48_2 PF02933.17 GAM21706.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Anti-TRAP PF15777.5 GAM21706.1 - 0.18 11.8 20.9 0.51 10.3 6.2 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 GAM21706.1 - 1.8 8.9 24.5 1.3 9.3 0.3 4.6 4 0 0 4 4 4 0 Family of unknown function (DUF5351) Defensin_propep PF00879.18 GAM21707.1 - 0.12 12.7 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 Defensin propeptide SpoVS PF04232.12 GAM21707.1 - 0.21 11.3 3.2 0.59 9.9 0.1 2.9 2 1 1 3 3 3 0 Stage V sporulation protein S (SpoVS) Methyltransf_2 PF00891.18 GAM21708.1 - 3.1e-46 157.3 0.0 3.8e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 GAM21708.1 - 2.5e-07 30.6 0.1 4.4e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_16 PF10294.9 GAM21709.1 - 4.2e-26 91.7 0.4 5.7e-26 91.3 0.4 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAM21709.1 - 3.3e-06 27.0 0.0 4.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM21709.1 - 7.5e-05 23.4 0.0 0.00017 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM21709.1 - 0.00039 21.1 0.0 0.00073 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM21709.1 - 0.0031 17.1 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain SAM_MT PF04445.13 GAM21709.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase GidB PF02527.15 GAM21709.1 - 0.064 12.6 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.12 GAM21709.1 - 0.081 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GAM21709.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 GAM21709.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Glycophorin_A PF01102.18 GAM21710.1 - 0.021 15.1 0.1 0.021 15.1 0.1 1.9 2 0 0 2 2 2 0 Glycophorin A tRNA-synt_1 PF00133.22 GAM21711.1 - 1.8e-224 746.5 0.3 2.4e-224 746.1 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM21711.1 - 1.5e-24 86.7 0.6 3.8e-24 85.4 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM21711.1 - 1.9e-15 56.5 1.3 0.0001 21.2 0.2 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAM21711.1 - 2.8e-05 23.6 0.0 7.4e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain YlbE PF14003.6 GAM21711.1 - 0.029 14.8 0.1 0.37 11.2 0.0 3.0 2 0 0 2 2 2 0 YlbE-like protein tRNA-synt_1_2 PF13603.6 GAM21711.1 - 0.043 13.3 0.1 0.74 9.3 0.0 2.4 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 DUF2457 PF10446.9 GAM21712.1 - 0.12 11.5 8.0 0.14 11.3 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.6 GAM21712.1 - 0.45 10.9 8.2 1.1 9.6 8.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MID_MedPIWI PF18296.1 GAM21714.1 - 4.1e-26 92.3 11.2 4.1e-26 92.3 11.2 6.2 3 2 0 4 4 4 1 MID domain of medPIWI Med13_C PF06333.12 GAM21714.1 - 2e-25 89.8 2.8 2.4e-20 73.1 0.6 7.3 3 3 3 7 7 7 2 Mediator complex subunit 13 C-terminal domain Coilin_N PF15862.5 GAM21714.1 - 0.11 12.3 16.4 9.2 6.1 0.0 4.2 3 1 1 4 4 4 0 Coilin N-terminus DUF3439 PF11921.8 GAM21714.1 - 1.5 8.8 13.7 0.1 12.6 7.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) PRIMA1 PF16101.5 GAM21715.1 - 0.0044 17.0 9.3 0.0097 15.9 9.3 1.6 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 EOS1 PF12326.8 GAM21715.1 - 0.13 12.2 0.1 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 N-glycosylation protein Mito_fiss_reg PF05308.11 GAM21715.1 - 0.51 10.4 16.4 0.043 13.9 9.1 2.2 1 1 1 2 2 2 0 Mitochondrial fission regulator adh_short PF00106.25 GAM21716.1 - 1.4e-23 83.4 0.1 4.1e-23 81.9 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM21716.1 - 2e-14 53.7 0.0 5.7e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM21716.1 - 1.9e-07 31.2 0.1 4e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM21716.1 - 0.028 13.9 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 GAM21716.1 - 0.056 12.7 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Imm68 PF15583.6 GAM21716.1 - 0.083 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 68 F420_oxidored PF03807.17 GAM21716.1 - 0.094 13.3 0.2 0.22 12.1 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Tim29 PF10171.9 GAM21716.1 - 0.72 9.3 2.8 10 5.6 0.9 2.4 2 1 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 CbiQ PF02361.16 GAM21718.1 - 4.4 6.9 11.2 4.9 6.7 11.2 1.0 1 0 0 1 1 1 0 Cobalt transport protein NOA36 PF06524.12 GAM21719.1 - 0.17 11.2 16.9 0.26 10.6 16.9 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 GAM21719.1 - 0.37 10.8 9.5 0.71 9.9 9.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 GAM21719.1 - 1.3 8.8 5.2 2.5 7.9 5.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.6 GAM21719.1 - 2.2 8.7 19.8 12 6.3 19.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIA PF03153.13 GAM21719.1 - 3.7 7.4 11.1 4.9 7.1 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 GAM21719.1 - 7.6 6.5 12.2 11 5.9 12.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Nop14 PF04147.12 GAM21719.1 - 8.7 4.4 10.0 13 3.8 10.0 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GAM21719.1 - 9.1 5.5 6.5 13 5.0 6.5 1.1 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.25 GAM21722.1 - 8.3e-31 107.3 0.0 2.3e-30 105.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21722.1 - 2.3e-23 82.8 0.0 8.8e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Dynamin_N PF00350.23 GAM21722.1 - 1.1e-13 51.6 0.1 4.1e-13 49.7 0.0 2.1 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 GAM21722.1 - 4.7e-06 26.7 0.0 2e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAM21722.1 - 0.044 14.3 0.0 0.18 12.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Band_7 PF01145.25 GAM21722.1 - 0.092 12.7 0.1 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 SPFH domain / Band 7 family AAA_18 PF13238.6 GAM21722.1 - 0.16 12.5 0.2 2.1 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 GAM21723.1 - 1.4e-08 35.0 0.1 4.6e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAM21723.1 - 0.00014 21.9 0.0 0.00058 19.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase CelTOS PF18659.1 GAM21723.1 - 0.0009 19.7 1.1 0.0029 18.0 1.1 1.8 1 0 0 1 1 1 1 Cell-traversal protein for ookinetes and sporozoites T2SSE PF00437.20 GAM21723.1 - 0.0055 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF445 PF04286.12 GAM21723.1 - 0.011 15.6 0.9 0.019 14.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Vps5 PF09325.10 GAM21723.1 - 0.031 13.8 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 Vps5 C terminal like RsgA_GTPase PF03193.16 GAM21723.1 - 0.038 13.9 0.2 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 GAM21723.1 - 0.062 13.8 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DOG1 PF14144.6 GAM21723.1 - 0.072 13.3 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 Seed dormancy control AAA_29 PF13555.6 GAM21723.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 GAM21724.1 - 2.4e-26 92.7 0.0 1.3e-25 90.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21724.1 - 2.9e-20 72.7 0.0 7.6e-20 71.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Dynamin_N PF00350.23 GAM21724.1 - 2.6e-10 40.6 0.0 9.3e-10 38.8 0.0 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAM21724.1 - 2.8e-05 24.2 0.0 0.00011 22.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2852 PF11014.8 GAM21724.1 - 0.021 15.0 2.4 0.045 13.9 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2852) AAA_33 PF13671.6 GAM21724.1 - 0.083 13.1 0.1 4.3 7.5 0.0 3.5 3 1 1 4 4 4 0 AAA domain Kdo PF06293.14 GAM21724.1 - 0.097 12.0 0.1 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFCD_C PF12612.8 GAM21724.1 - 0.16 11.8 1.0 1.1 9.1 0.2 2.6 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal Pkinase PF00069.25 GAM21725.1 - 1.1e-15 57.8 1.8 3.1e-15 56.3 1.8 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21725.1 - 2.2e-12 46.8 0.9 1.1e-11 44.6 0.9 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM21725.1 - 0.033 13.0 0.9 0.06 12.1 0.9 1.4 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 GAM21726.1 - 2e-16 60.2 0.1 1.4e-15 57.4 0.1 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21726.1 - 1.9e-13 50.3 0.1 1.6e-12 47.3 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Dynamin_N PF00350.23 GAM21726.1 - 2.7e-06 27.5 0.0 6.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Haspin_kinase PF12330.8 GAM21726.1 - 6.6e-06 25.3 0.6 1.7e-05 23.9 0.3 1.7 1 1 0 1 1 1 1 Haspin like kinase domain MMR_HSR1 PF01926.23 GAM21726.1 - 0.041 14.0 0.0 0.35 11.0 0.0 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pkinase_fungal PF17667.1 GAM21726.1 - 0.072 11.9 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Dynamin_N PF00350.23 GAM21727.1 - 6.4e-11 42.6 0.0 1.6e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Pkinase_Tyr PF07714.17 GAM21727.1 - 1.9e-09 37.2 0.4 1.3e-05 24.6 0.3 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase MMR_HSR1 PF01926.23 GAM21727.1 - 3.6e-06 27.0 0.0 2.1e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Pkinase PF00069.25 GAM21727.1 - 3.1e-05 23.5 5.7 0.00085 18.8 1.4 2.9 2 1 0 2 2 2 1 Protein kinase domain AAA_22 PF13401.6 GAM21727.1 - 0.025 14.8 0.1 0.71 10.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GAM21727.1 - 0.03 13.5 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 GAM21727.1 - 0.048 13.7 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 GAM21727.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 GAM21727.1 - 0.08 13.5 0.9 0.25 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SET PF00856.28 GAM21728.1 - 3.7e-09 37.2 0.2 5.2e-09 36.7 0.2 1.4 1 1 0 1 1 1 1 SET domain SET PF00856.28 GAM21729.1 - 6.6e-14 52.6 0.4 6.6e-14 52.6 0.4 2.6 2 2 0 2 2 2 1 SET domain TPR_2 PF07719.17 GAM21729.1 - 5.1e-06 26.2 0.6 0.021 14.9 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM21729.1 - 0.005 16.6 0.6 0.12 12.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM21729.1 - 0.012 15.8 0.3 5 7.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM21729.1 - 0.042 13.5 0.6 0.091 12.5 0.2 1.8 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 GAM21729.1 - 0.096 13.1 0.0 0.31 11.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat adh_short PF00106.25 GAM21730.1 - 8.1e-49 165.7 0.0 1.2e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM21730.1 - 7e-35 120.7 0.0 9.6e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM21730.1 - 6e-12 45.8 0.0 9e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM21730.1 - 6.5e-05 22.5 0.2 0.00015 21.3 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM21730.1 - 0.00015 21.7 0.1 0.00026 21.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding FAM176 PF14851.6 GAM21731.1 - 0.063 12.9 4.5 0.071 12.8 4.5 1.1 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 GAM21731.1 - 0.085 13.1 7.9 0.1 12.8 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2457 PF10446.9 GAM21731.1 - 0.18 10.9 11.1 0.2 10.8 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 GAM21731.1 - 0.22 11.4 6.7 0.24 11.3 6.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 GAM21731.1 - 0.25 11.7 9.7 0.3 11.5 9.7 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 GAM21731.1 - 0.29 9.4 7.6 0.28 9.4 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 GAM21731.1 - 0.52 8.3 8.8 0.52 8.3 8.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 GAM21731.1 - 0.82 8.9 12.3 0.89 8.8 12.3 1.0 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GAM21731.1 - 4.3 5.3 9.2 4.2 5.4 9.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GAM21731.1 - 4.4 5.7 8.1 4.3 5.8 8.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Glyco_hydro_31 PF01055.26 GAM21733.1 - 1.1e-146 489.5 6.9 1.5e-146 489.1 6.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAM21733.1 - 4.1e-24 84.7 0.1 2.4e-23 82.2 0.1 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 GAM21733.1 - 1.7e-07 31.4 0.1 5.3e-07 29.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) GATA PF00320.27 GAM21734.1 - 7.6e-14 51.0 5.7 7.6e-14 51.0 5.7 2.3 2 0 0 2 2 2 1 GATA zinc finger zinc_ribbon_9 PF14369.6 GAM21734.1 - 0.76 10.1 2.8 1.9 8.8 2.8 1.7 1 0 0 1 1 1 0 zinc-ribbon YlbD_coat PF14071.6 GAM21734.1 - 5.4 7.3 5.2 23 5.2 5.2 2.0 1 0 0 1 1 1 0 Putative coat protein Uma2 PF05685.12 GAM21735.1 - 2.7e-07 30.3 0.0 7.9e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Putative restriction endonuclease Tom37 PF10568.9 GAM21735.1 - 0.042 14.1 0.0 0.083 13.2 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein KxDL PF10241.9 GAM21735.1 - 0.3 11.4 3.5 0.54 10.6 3.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein Dynamin_N PF00350.23 GAM21736.1 - 1.6e-38 132.4 5.0 8.4e-38 130.1 0.1 2.6 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAM21736.1 - 4.3e-06 26.8 0.3 6.8e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Herpes_pp85 PF04637.12 GAM21736.1 - 0.00085 17.9 0.2 0.0026 16.3 0.2 1.8 2 0 0 2 2 2 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) HSP70 PF00012.20 GAM21736.1 - 0.083 11.1 4.3 0.17 10.0 4.3 1.4 1 0 0 1 1 1 0 Hsp70 protein U79_P34 PF03064.16 GAM21736.1 - 2 7.7 9.1 4.2 6.7 9.1 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FNIP PF05725.12 GAM21737.1 - 2.9e-26 91.3 20.2 2e-12 47.1 1.5 7.4 5 2 3 8 8 8 6 FNIP Repeat DUF1769 PF08588.10 GAM21737.1 - 0.017 15.3 0.0 1.5 9.1 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1769) FNIP PF05725.12 GAM21738.1 - 3.3e-19 68.8 2.7 5e-08 33.0 0.0 5.7 6 0 0 6 6 6 5 FNIP Repeat F-box_5 PF18511.1 GAM21738.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 F-box Ank_2 PF12796.7 GAM21739.1 - 0.028 15.0 17.4 0.21 12.2 2.0 6.5 7 2 0 7 7 7 0 Ankyrin repeats (3 copies) EF-hand_2 PF09068.11 GAM21739.1 - 0.035 14.3 0.2 0.83 9.8 0.0 3.4 2 1 1 3 3 3 0 EF hand Sec7 PF01369.20 GAM21739.1 - 0.038 13.7 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Sec7 domain Ank_5 PF13857.6 GAM21739.1 - 0.039 14.3 4.3 83 3.7 0.0 7.3 8 1 1 9 9 9 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM21739.1 - 0.042 14.4 3.5 1.6e+02 3.0 0.0 6.6 6 2 0 6 6 6 0 Ankyrin repeats (many copies) FPL PF09758.9 GAM21739.1 - 0.51 10.3 4.6 10 6.1 0.2 4.0 4 1 0 4 4 4 0 Uncharacterised conserved protein FNIP PF05725.12 GAM21740.1 - 3.8e-16 59.0 16.6 8.1e-08 32.3 1.2 5.6 2 2 3 5 5 5 5 FNIP Repeat FNIP PF05725.12 GAM21741.1 - 9.1e-08 32.1 1.9 0.022 14.9 0.0 3.8 3 1 0 3 3 3 2 FNIP Repeat SET PF00856.28 GAM21742.1 - 3.5e-11 43.8 0.3 3.5e-11 43.8 0.3 3.1 3 1 0 3 3 3 1 SET domain TPR_20 PF14561.6 GAM21742.1 - 0.00015 22.0 0.4 0.00055 20.2 0.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAM21742.1 - 0.0005 19.7 0.1 0.082 12.6 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.6 GAM21742.1 - 0.00084 19.2 0.3 0.42 10.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM21742.1 - 0.0012 18.6 2.3 0.26 11.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM21742.1 - 0.0043 17.5 0.0 0.03 14.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM21742.1 - 0.0082 16.5 0.0 0.028 14.8 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21742.1 - 0.021 14.9 0.9 0.81 9.9 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Cnn_1N PF07989.11 GAM21742.1 - 0.028 14.6 3.5 0.21 11.8 4.3 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Noc2 PF03715.13 GAM21742.1 - 0.06 12.6 2.2 0.15 11.2 1.4 2.0 2 0 0 2 2 2 0 Noc2p family TFIIA PF03153.13 GAM21742.1 - 0.071 13.1 28.4 0.029 14.4 18.0 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Csm2_III-A PF03750.13 GAM21742.1 - 0.072 13.9 1.7 0.98 10.3 0.3 2.6 2 0 0 2 2 2 0 Csm2 Type III-A TPR_8 PF13181.6 GAM21742.1 - 0.11 12.8 0.2 0.77 10.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SDA1 PF05285.12 GAM21742.1 - 0.53 9.7 29.6 0.013 15.0 21.3 2.1 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 GAM21742.1 - 1 7.5 39.9 0.37 9.0 26.9 2.3 2 0 0 2 2 2 0 Nop14-like family Chalcone_3 PF16036.5 GAM21742.1 - 1.2 9.2 4.4 1.9 8.6 2.7 2.0 2 0 0 2 2 2 0 Chalcone isomerase-like SET PF00856.28 GAM21743.1 - 7.8e-08 32.9 0.2 1.7e-07 31.8 0.2 1.5 1 0 0 1 1 1 1 SET domain DUF3268 PF11672.8 GAM21743.1 - 0.0014 19.0 0.1 0.0024 18.2 0.1 1.4 1 0 0 1 1 1 1 zinc-finger-containing domain Spt4 PF06093.13 GAM21743.1 - 0.019 15.0 1.5 0.042 13.9 1.5 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger zinc-ribbons_6 PF07191.12 GAM21743.1 - 0.029 14.3 3.3 0.044 13.8 2.3 1.7 2 0 0 2 2 2 0 zinc-ribbons HypA PF01155.19 GAM21743.1 - 0.065 13.3 0.9 0.14 12.2 0.9 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SET PF00856.28 GAM21746.1 - 2.3e-09 37.9 0.1 2.3e-09 37.9 0.1 2.0 3 0 0 3 3 3 1 SET domain FYVE PF01363.21 GAM21746.1 - 0.0094 16.1 2.6 0.018 15.1 2.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger AAA_22 PF13401.6 GAM21748.1 - 0.0031 17.8 0.0 0.0071 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 GAM21748.1 - 0.01 15.1 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain DUF1870 PF08965.10 GAM21748.1 - 0.14 12.1 0.2 8.7 6.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) DUF4261 PF14080.6 GAM21749.1 - 0.1 12.8 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) SET PF00856.28 GAM21750.1 - 2.4e-10 41.0 1.6 2.4e-10 41.0 1.6 2.2 2 1 0 2 2 2 1 SET domain FYVE PF01363.21 GAM21750.1 - 0.0011 19.0 3.4 0.0011 19.0 3.4 2.4 2 0 0 2 2 2 1 FYVE zinc finger TPR_1 PF00515.28 GAM21750.1 - 0.0017 18.1 0.0 0.2 11.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM21750.1 - 0.036 14.4 0.1 1.7 9.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat G6PD_N PF00479.22 GAM21750.1 - 0.038 14.6 0.6 0.81 10.3 0.0 3.1 3 1 0 3 3 3 0 Glucose-6-phosphate dehydrogenase, NAD binding domain TPR_8 PF13181.6 GAM21750.1 - 0.04 14.1 0.1 0.23 11.7 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM21750.1 - 0.076 12.7 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 TPR repeat VWA_N PF08399.11 GAM21750.1 - 5.5 7.5 6.6 5.7 7.4 0.5 3.2 2 1 1 3 3 3 0 VWA N-terminal SET PF00856.28 GAM21751.1 - 1.8e-12 48.0 0.8 7.5e-12 46.0 0.8 2.0 1 1 0 1 1 1 1 SET domain Stc1 PF12898.7 GAM21751.1 - 0.033 14.7 1.6 0.033 14.7 1.6 2.7 2 1 0 2 2 2 0 Stc1 domain CheB_methylest PF01339.17 GAM21751.1 - 0.1 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 CheB methylesterase HypA PF01155.19 GAM21751.1 - 0.23 11.5 10.1 0.68 10.0 0.8 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYVE_2 PF02318.16 GAM21751.1 - 6 7.1 15.6 0.21 11.8 7.2 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger SET PF00856.28 GAM21752.1 - 1.8e-10 41.5 1.1 8e-10 39.4 1.1 2.1 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 GAM21752.1 - 3.6e-07 29.7 0.0 0.00014 21.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21752.1 - 5.1e-05 23.1 0.1 0.019 15.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM21752.1 - 0.00036 20.8 0.6 0.005 17.1 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAM21752.1 - 0.00045 19.8 0.0 0.074 12.7 0.0 2.9 2 1 1 3 3 3 2 TPR repeat TPR_7 PF13176.6 GAM21752.1 - 0.00083 19.2 0.1 0.0058 16.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM21752.1 - 0.00086 19.5 1.6 0.0042 17.4 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM21752.1 - 0.002 17.9 0.0 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM21752.1 - 0.022 14.9 0.1 0.072 13.3 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat HypA PF01155.19 GAM21752.1 - 0.075 13.1 6.7 0.45 10.5 0.4 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Acetone_carb_G PF08882.11 GAM21752.1 - 0.085 13.0 0.6 0.27 11.4 0.1 2.1 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit TPR_19 PF14559.6 GAM21752.1 - 0.096 13.2 0.0 0.64 10.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAM21752.1 - 0.11 12.8 0.1 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 GAM21752.1 - 0.13 11.7 0.1 0.13 11.7 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain BTAD PF03704.17 GAM21752.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_14 PF13428.6 GAM21752.1 - 0.2 12.5 0.0 1.4 10.0 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat zinc-ribbons_6 PF07191.12 GAM21752.1 - 0.54 10.3 17.5 0.033 14.2 4.3 2.8 2 0 0 2 2 2 0 zinc-ribbons SET PF00856.28 GAM21753.1 - 2.9e-11 44.0 2.2 8.6e-11 42.5 2.2 1.9 1 1 0 1 1 1 1 SET domain TPR_7 PF13176.6 GAM21753.1 - 0.018 15.0 1.8 30 4.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Laminin_B PF00052.18 GAM21753.1 - 0.029 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Laminin B (Domain IV) SAF PF08666.12 GAM21753.1 - 0.13 12.9 0.1 17 6.2 0.0 2.7 2 0 0 2 2 2 0 SAF domain HypA PF01155.19 GAM21753.1 - 0.34 11.0 8.5 0.33 11.0 0.1 2.8 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBR PF01485.21 GAM21753.1 - 1.8 8.9 15.9 8.5 6.7 6.8 2.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain TPR_2 PF07719.17 GAM21753.1 - 4.6 7.6 12.1 4.1 7.7 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat FYVE_2 PF02318.16 GAM21753.1 - 6.6 7.0 18.1 0.23 11.7 8.0 3.0 3 0 0 3 3 3 0 FYVE-type zinc finger SET PF00856.28 GAM21754.1 - 3e-10 40.8 0.1 1.1e-09 38.9 0.1 1.9 1 0 0 1 1 1 1 SET domain TPR_1 PF00515.28 GAM21754.1 - 0.0001 22.0 0.1 0.13 12.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat FYVE PF01363.21 GAM21754.1 - 0.00018 21.5 10.9 0.0059 16.7 2.6 2.5 2 0 0 2 2 2 2 FYVE zinc finger TPR_17 PF13431.6 GAM21754.1 - 0.0018 18.5 0.1 0.031 14.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21754.1 - 0.014 15.5 0.1 0.35 11.1 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAM21754.1 - 0.021 15.1 0.3 0.063 13.6 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat HypA PF01155.19 GAM21754.1 - 0.021 14.8 5.4 0.66 10.0 1.1 2.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4807 PF16065.5 GAM21754.1 - 0.028 14.1 0.8 0.31 10.7 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4807) TPR_11 PF13414.6 GAM21754.1 - 0.03 14.0 1.7 0.38 10.5 0.0 3.1 3 1 1 4 4 4 0 TPR repeat TPR_12 PF13424.6 GAM21754.1 - 0.049 13.9 2.9 0.57 10.5 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM21754.1 - 0.05 14.1 0.3 0.13 12.8 0.0 1.9 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM21754.1 - 0.066 14.1 0.4 1.7 9.6 0.0 3.2 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM21754.1 - 0.2 11.8 4.8 3 8.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2564 PF10819.8 GAM21754.1 - 0.25 11.7 1.5 1.5 9.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) DZR PF12773.7 GAM21754.1 - 2.6 8.1 16.2 2.8 8.1 4.5 2.7 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 GAM21754.1 - 8.9 6.2 12.6 3.9 7.3 0.8 3.3 2 1 2 4 4 4 0 zinc-ribbon domain DUF4868 PF16162.5 GAM21755.1 - 0.042 13.8 0.4 0.059 13.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4868) TPR_12 PF13424.6 GAM21755.1 - 0.051 13.9 0.0 0.26 11.6 0.0 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM21755.1 - 0.058 13.2 0.1 6.5 6.8 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM21755.1 - 0.11 12.8 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SET PF00856.28 GAM21756.1 - 2.1e-09 38.0 0.8 9.1e-09 35.9 0.8 2.1 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.6 GAM21756.1 - 0.00013 22.2 0.7 0.0099 16.2 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM21756.1 - 0.00032 21.2 0.4 0.037 14.5 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM21756.1 - 0.024 14.5 0.1 0.22 11.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAM21756.1 - 0.058 13.5 0.3 3.5 7.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21756.1 - 0.076 13.2 1.3 17 5.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf_UBZ PF18439.1 GAM21756.1 - 0.21 11.2 6.6 1.2 8.8 0.1 2.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-TFIIB PF13453.6 GAM21756.1 - 0.64 9.4 10.1 0.91 8.9 0.2 2.9 3 0 0 3 3 2 0 Transcription factor zinc-finger zf-ACC PF17848.1 GAM21756.1 - 0.66 10.1 5.7 24 5.1 0.1 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain Acetone_carb_G PF08882.11 GAM21756.1 - 4.4 7.5 5.9 4.5 7.5 0.1 3.2 3 0 0 3 3 3 0 Acetone carboxylase gamma subunit zf-ribbon_3 PF13248.6 GAM21756.1 - 5.3 6.6 8.1 1.9 8.0 0.5 2.7 2 1 0 2 2 2 0 zinc-ribbon domain zf_C2H2_10 PF18414.1 GAM21756.1 - 9.4 5.9 8.3 15 5.2 0.2 2.9 2 0 0 2 2 2 0 C2H2 type zinc-finger FNIP PF05725.12 GAM21757.1 - 9.3e-27 92.9 20.5 2e-09 37.4 0.1 7.1 5 2 2 7 7 7 5 FNIP Repeat Antistasin PF02822.14 GAM21757.1 - 0.18 12.5 0.2 0.34 11.6 0.2 1.4 1 0 0 1 1 1 0 Antistasin family SET PF00856.28 GAM21758.1 - 1.1e-10 42.2 1.0 5.6e-10 39.9 0.1 2.3 2 1 0 2 2 2 1 SET domain Acetone_carb_G PF08882.11 GAM21758.1 - 0.028 14.6 0.1 0.081 13.1 0.1 1.8 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit DZR PF12773.7 GAM21758.1 - 0.052 13.6 9.7 2 8.5 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon Spt4 PF06093.13 GAM21758.1 - 0.058 13.5 0.8 0.33 11.1 0.8 2.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger zinc_ribbon_2 PF13240.6 GAM21758.1 - 0.4 10.5 7.2 0.25 11.1 3.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 GAM21758.1 - 2.5 8.2 11.1 0.62 10.1 2.6 2.7 2 1 1 3 3 3 0 zinc-ribbons zf-RING_4 PF14570.6 GAM21758.1 - 6.2 6.7 11.6 5.4 6.9 0.7 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ribbon_3 PF13248.6 GAM21758.1 - 7.2 6.2 8.3 4 7.0 4.6 2.5 2 1 0 2 2 2 0 zinc-ribbon domain FYVE PF01363.21 GAM21759.1 - 3e-17 62.5 10.2 3e-17 62.5 10.2 2.3 2 1 0 2 2 2 1 FYVE zinc finger Arrestin_N PF00339.29 GAM21759.1 - 2.3e-15 56.9 3.1 3.6e-11 43.3 0.4 3.2 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAM21759.1 - 2.2e-14 54.0 0.9 1.4e-12 48.2 0.2 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 GAM21759.1 - 0.0097 15.6 0.1 0.033 13.9 0.0 2.1 2 1 0 2 2 2 1 Arrestin_N terminal like Rgp1 PF08737.10 GAM21759.1 - 0.014 14.6 0.3 0.11 11.6 0.0 2.3 2 1 1 3 3 3 0 Rgp1 FYVE_2 PF02318.16 GAM21759.1 - 0.018 15.3 6.0 0.018 15.3 6.0 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger Ank_2 PF12796.7 GAM21760.1 - 2.9e-07 31.0 2.8 1.4 9.5 0.3 8.0 7 2 0 7 7 7 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM21760.1 - 0.0004 20.6 0.9 12 6.4 0.1 5.7 6 0 0 6 6 6 2 Ankyrin repeats (many copies) DUF366 PF04017.12 GAM21760.1 - 0.0079 15.7 0.5 0.043 13.3 0.5 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF366) BolA PF01722.18 GAM21760.1 - 0.058 13.7 0.2 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 BolA-like protein Ank_3 PF13606.6 GAM21760.1 - 0.66 10.7 5.5 8.7e+02 1.1 0.0 7.3 8 0 0 8 8 8 0 Ankyrin repeat FNIP PF05725.12 GAM21761.1 - 3.8e-16 59.0 14.1 2.4e-08 34.0 0.4 7.1 5 2 2 7 7 7 4 FNIP Repeat F-box_5 PF18511.1 GAM21761.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box F-box PF00646.33 GAM21761.1 - 0.65 9.9 5.1 1.1 9.2 0.7 3.3 3 1 0 4 4 4 0 F-box domain FNIP PF05725.12 GAM21762.1 - 2.3e-08 34.0 9.6 2.4e-05 24.4 0.1 5.2 4 1 1 5 5 5 5 FNIP Repeat DUF3019 PF11456.8 GAM21763.1 - 0.043 14.3 0.3 0.05 14.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3019) FNIP PF05725.12 GAM21764.1 - 3.1e-25 88.1 23.7 3.2e-13 49.6 0.9 7.1 5 2 4 9 9 9 7 FNIP Repeat FNIP PF05725.12 GAM21765.1 - 3.3e-20 72.0 31.1 1.3e-11 44.5 2.1 7.3 6 1 1 7 7 7 6 FNIP Repeat FNIP PF05725.12 GAM21766.1 - 9.8e-24 83.3 17.8 2.3e-11 43.7 1.2 7.6 5 2 4 9 9 9 6 FNIP Repeat F-box_5 PF18511.1 GAM21766.1 - 0.0083 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 GAM21766.1 - 0.054 13.4 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 F-box-like FNIP PF05725.12 GAM21767.1 - 1e-42 144.0 19.9 6.3e-15 55.1 1.2 7.1 7 0 0 7 7 7 6 FNIP Repeat PSI PF01437.25 GAM21768.1 - 0.00017 22.0 15.0 0.00031 21.2 15.0 1.5 1 0 0 1 1 1 1 Plexin repeat Comm PF15957.5 GAM21768.1 - 0.013 15.9 0.2 0.019 15.3 0.2 1.2 1 0 0 1 1 1 0 Commissureless FAM163 PF15069.6 GAM21768.1 - 0.016 15.6 0.4 0.016 15.6 0.4 1.8 2 0 0 2 2 2 0 FAM163 family MLANA PF14991.6 GAM21768.1 - 0.12 12.7 0.3 0.17 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein melan-A Baculo_11_kDa PF06143.11 GAM21768.1 - 0.15 11.6 0.7 0.25 10.9 0.7 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMEM154 PF15102.6 GAM21768.1 - 0.17 11.8 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Orthoreo_P10 PF07204.11 GAM21768.1 - 1.2 9.1 13.2 12 5.9 13.2 2.0 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Ank_2 PF12796.7 GAM21769.1 - 1.1e-09 38.8 8.3 0.065 13.8 0.3 6.9 6 3 3 9 9 9 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM21769.1 - 1.6e-09 38.1 13.6 0.035 14.7 0.0 7.5 6 1 2 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM21769.1 - 0.00062 20.0 6.3 1.6e+02 3.4 0.0 9.2 10 0 0 10 10 10 0 Ankyrin repeat Ank_5 PF13857.6 GAM21769.1 - 0.0044 17.3 0.3 85 3.6 0.0 6.4 8 1 1 9 9 9 0 Ankyrin repeats (many copies) Cpn60_TCP1 PF00118.24 GAM21770.1 - 8.7e-115 384.1 0.7 1e-114 383.9 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PucR PF07905.11 GAM21770.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family TP_methylase PF00590.20 GAM21771.1 - 1.3e-22 80.8 0.0 3e-22 79.6 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ras PF00071.22 GAM21772.1 - 1.4e-47 161.3 0.0 1.6e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM21772.1 - 8.3e-21 74.4 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM21772.1 - 2.8e-06 26.9 0.0 3.8e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 GAM21772.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 GAM21772.1 - 0.073 12.8 0.0 9.1 6.0 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 GAM21772.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase CLP1_P PF16575.5 GAM21773.1 - 1.9e-63 213.7 0.0 2.7e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 GAM21773.1 - 4e-33 114.3 0.0 7.5e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 GAM21773.1 - 6e-25 87.3 0.1 9.7e-25 86.6 0.1 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor MMR_HSR1 PF01926.23 GAM21773.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 GAM21773.1 - 0.049 14.2 0.0 0.096 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM21773.1 - 0.05 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 GAM21773.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 GAM21773.1 - 0.052 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 GAM21773.1 - 0.17 11.9 0.0 0.51 10.4 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain LIM PF00412.22 GAM21774.1 - 1.6e-58 194.8 44.8 9.5e-16 57.8 5.3 4.0 4 0 0 4 4 4 4 LIM domain WRC PF08879.10 GAM21774.1 - 0.48 10.2 0.1 0.48 10.2 0.1 4.2 6 0 0 6 6 6 0 WRC Lipoprotein_15 PF03640.15 GAM21774.1 - 0.83 9.2 6.4 18 5.0 0.1 4.0 4 0 0 4 4 4 0 Secreted repeat of unknown function PPR_3 PF13812.6 GAM21776.1 - 9.1e-10 38.5 12.3 0.014 15.5 0.0 6.6 7 0 0 7 7 7 4 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAM21776.1 - 3.3e-09 36.8 7.9 0.0018 18.4 0.0 7.3 8 0 0 8 8 8 2 PPR repeat family PPR PF01535.20 GAM21776.1 - 0.00015 21.7 1.2 9.3 6.7 0.0 5.8 7 0 0 7 7 7 2 PPR repeat CDC50 PF03381.15 GAM21776.1 - 0.0063 16.1 0.4 0.0063 16.1 0.4 2.6 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family TPR_8 PF13181.6 GAM21776.1 - 0.032 14.4 0.2 1.2 9.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Mem_trans PF03547.18 GAM21776.1 - 0.094 11.1 0.1 0.13 10.6 0.1 1.3 1 0 0 1 1 1 0 Membrane transport protein Sel1 PF08238.12 GAM21776.1 - 0.12 13.1 3.2 3.1 8.6 0.1 3.5 4 0 0 4 4 4 0 Sel1 repeat rRNA_proc-arch PF13234.6 GAM21777.1 - 3.4e-66 223.9 2.4 3.4e-66 223.9 2.4 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 GAM21777.1 - 2e-47 160.9 0.0 5.9e-47 159.4 0.0 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 GAM21777.1 - 9.4e-18 64.6 1.6 1.7e-17 63.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM21777.1 - 2.4e-06 27.9 0.2 2e-05 24.9 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAM21777.1 - 0.19 12.0 1.4 0.85 9.9 0.0 3.0 4 0 0 4 4 4 0 AAA domain Kelch_6 PF13964.6 GAM21778.1 - 8.5e-11 41.7 7.1 0.00013 22.1 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 GAM21778.1 - 6.1e-10 38.5 4.0 2.5e-05 23.7 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM21778.1 - 3.1e-09 36.7 6.7 6.7e-05 22.8 0.0 4.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM21778.1 - 2.9e-06 27.0 6.6 0.26 11.3 0.0 5.6 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 GAM21778.1 - 3.3e-06 27.2 3.6 0.019 15.2 0.0 5.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM21778.1 - 0.26 11.3 10.4 4.1 7.5 0.3 5.2 5 0 0 5 5 5 0 Kelch motif FYDLN_acid PF09538.10 GAM21779.1 - 0.0034 18.0 5.8 0.01 16.5 5.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) RRN3 PF05327.11 GAM21779.1 - 0.33 9.4 7.7 0.45 9.0 7.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 GAM21779.1 - 0.4 10.6 11.5 0.026 14.5 6.6 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IFT57 PF10498.9 GAM21779.1 - 0.51 9.3 3.9 0.75 8.7 3.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nop14 PF04147.12 GAM21779.1 - 1.8 6.7 11.4 2.7 6.1 11.4 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GAM21779.1 - 2.6 6.0 18.1 3.7 5.5 18.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi SSP160 PF06933.11 GAM21779.1 - 3.4 5.8 17.5 4.4 5.4 17.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SDA1 PF05285.12 GAM21779.1 - 4.4 6.6 10.6 6.2 6.1 10.6 1.2 1 0 0 1 1 1 0 SDA1 Tir_receptor_C PF07489.11 GAM21779.1 - 5.5 6.9 12.1 8.4 6.3 12.1 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus COPI_C PF06957.11 GAM21779.1 - 6.4 5.4 6.5 9.9 4.8 6.5 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus BUD22 PF09073.10 GAM21779.1 - 8.8 5.5 10.4 13 5.0 10.4 1.2 1 0 0 1 1 1 0 BUD22 TPR_8 PF13181.6 GAM21780.1 - 0.13 12.5 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Kelch_6 PF13964.6 GAM21781.1 - 4.1e-14 52.3 1.2 0.0053 17.0 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM21781.1 - 1.9e-10 40.6 3.2 0.0087 16.0 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM21781.1 - 6.7e-08 32.6 1.4 1.6 9.1 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM21781.1 - 3.1e-07 29.9 0.9 1.2 8.8 0.0 4.8 5 0 0 5 5 5 3 Kelch motif zf-B_box PF00643.24 GAM21781.1 - 9.1e-07 28.9 11.6 2.4e-06 27.6 11.6 1.7 1 0 0 1 1 1 1 B-box zinc finger Kelch_5 PF13854.6 GAM21781.1 - 1.6e-05 24.8 1.2 0.31 11.1 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 GAM21781.1 - 0.00015 21.6 0.8 1 9.4 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Baculo_PEP_C PF04513.12 GAM21781.1 - 0.0011 19.1 1.8 0.0024 17.9 1.8 1.6 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus C1_2 PF03107.16 GAM21781.1 - 0.13 12.6 5.6 0.29 11.5 5.6 1.7 1 0 0 1 1 1 0 C1 domain Kelch_6 PF13964.6 GAM21782.1 - 4.6e-17 61.6 5.2 6.3e-05 23.1 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 GAM21782.1 - 2.1e-11 43.6 8.5 0.00016 21.6 0.1 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM21782.1 - 8.4e-07 29.1 0.3 9.2 6.7 0.0 5.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM21782.1 - 8.1e-06 25.6 9.7 0.0073 16.3 0.1 4.8 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 GAM21782.1 - 0.0001 21.8 5.4 0.18 11.4 0.0 5.0 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.6 GAM21782.1 - 0.0041 17.1 10.2 0.1 12.6 0.7 4.2 4 0 0 4 4 4 2 Kelch motif PSD3 PF07626.11 GAM21782.1 - 0.18 12.3 0.1 0.5 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) Kelch_6 PF13964.6 GAM21784.1 - 2.1e-08 34.1 8.1 0.0051 17.0 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 GAM21784.1 - 0.00044 20.2 10.2 0.025 14.6 0.1 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM21784.1 - 0.0019 17.8 4.0 1.8 8.2 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAM21784.1 - 0.12 12.4 8.0 1.2 9.2 0.1 3.8 4 1 0 4 4 4 0 Kelch motif Kelch_5 PF13854.6 GAM21784.1 - 0.35 10.9 13.7 3 7.9 2.0 3.9 3 1 1 4 4 4 0 Kelch motif 6PF2K PF01591.18 GAM21785.1 - 4.3e-64 215.9 1.0 7.2e-64 215.1 1.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAM21785.1 - 4e-31 108.2 0.0 9e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAM21785.1 - 9.2e-06 25.9 0.2 2.8e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AIP3 PF03915.13 GAM21785.1 - 0.00054 19.2 0.1 0.00054 19.2 0.1 2.3 1 1 1 2 2 2 1 Actin interacting protein 3 Zeta_toxin PF06414.12 GAM21785.1 - 0.034 13.4 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 GAM21785.1 - 0.039 13.4 0.0 0.039 13.4 0.0 2.2 3 0 0 3 3 3 0 Chromatin associated protein KTI12 DUF1460 PF07313.12 GAM21785.1 - 0.069 12.5 0.6 0.16 11.3 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1460) NB-ARC PF00931.22 GAM21785.1 - 0.094 11.9 0.2 0.3 10.2 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 GAM21785.1 - 0.13 12.8 0.1 0.95 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAM21785.1 - 0.14 11.5 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Abhydrolase_1 PF00561.20 GAM21787.1 - 0.023 14.4 0.2 0.039 13.6 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Tmemb_185A PF10269.9 GAM21788.1 - 5.5e-11 42.6 17.9 8.8e-11 42.0 17.9 1.3 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein Pkinase_Tyr PF07714.17 GAM21790.1 - 2.4e-63 213.8 0.0 3.5e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM21790.1 - 1.6e-49 168.7 0.0 3.7e-49 167.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 GAM21790.1 - 1.9e-05 24.1 0.0 3.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAM21790.1 - 0.0026 16.8 0.0 0.0026 16.8 0.0 2.7 3 0 0 3 3 3 2 Haspin like kinase domain Kdo PF06293.14 GAM21790.1 - 0.011 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAM21790.1 - 0.012 14.7 0.1 0.029 13.4 0.1 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 TIG PF01833.24 GAM21791.1 - 1.2e-08 34.9 19.6 2.5e-07 30.7 3.9 3.7 2 1 1 3 3 3 3 IPT/TIG domain Proteasome PF00227.26 GAM21792.1 - 8.6e-58 195.0 0.3 1.3e-57 194.4 0.3 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM21792.1 - 4.1e-14 51.9 0.1 8.1e-14 51.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Phosphodiest PF01663.22 GAM21793.1 - 8.7e-08 32.1 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Renin_r PF07850.14 GAM21793.1 - 0.0014 19.2 0.1 0.0056 17.2 0.1 2.0 2 0 0 2 2 2 1 Renin receptor-like protein GMC_oxred_C PF05199.13 GAM21793.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 GMC oxidoreductase DUF2897 PF11446.8 GAM21793.1 - 0.37 10.7 5.9 0.16 11.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) PAP_assoc PF03828.19 GAM21794.1 - 5.6e-14 52.1 0.8 1.5e-13 50.8 0.8 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAM21794.1 - 1.3e-07 31.8 1.7 8.6e-07 29.2 0.0 2.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAM21794.1 - 0.00019 21.5 1.6 0.00087 19.3 0.0 3.0 3 0 0 3 3 3 1 Polymerase beta, Nucleotidyltransferase ZnuA PF01297.17 GAM21794.1 - 0.1 12.0 2.9 0.22 10.9 2.9 1.6 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic T3SSipB PF16535.5 GAM21794.1 - 0.14 12.6 4.3 0.069 13.6 0.5 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB MMR_HSR1_Xtn PF16897.5 GAM21794.1 - 0.46 10.5 4.9 1.8 8.6 4.9 2.1 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Shikimate_dh_N PF08501.11 GAM21795.1 - 0.14 12.4 0.2 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate dehydrogenase substrate binding domain Kelch_6 PF13964.6 GAM21796.1 - 1.1e-11 44.5 4.6 0.00069 19.8 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAM21796.1 - 3.6e-05 23.3 0.6 2.2 8.0 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM21796.1 - 4.9e-05 23.2 14.7 0.0012 18.8 0.0 5.5 4 2 1 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM21796.1 - 0.2 11.7 4.8 30 4.7 0.1 3.7 3 1 0 3 3 3 0 Kelch motif LOH1CR12 PF10158.9 GAM21796.1 - 0.33 11.0 6.7 2.6 8.1 0.5 3.1 2 1 1 3 3 3 0 Tumour suppressor protein TPR_19 PF14559.6 GAM21797.1 - 1.7e-07 31.6 1.0 0.015 15.8 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21797.1 - 5.4e-06 26.1 0.3 0.09 12.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM21797.1 - 1e-05 25.7 4.6 0.63 10.4 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM21797.1 - 8.9e-05 22.6 3.8 1.4 9.4 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM21797.1 - 0.00011 21.8 0.2 1.7 8.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM21797.1 - 0.00016 22.1 5.6 19 6.1 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM21797.1 - 0.00017 22.2 0.1 22 6.2 0.0 5.0 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAM21797.1 - 0.14 12.5 0.2 11 6.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM21797.1 - 0.23 11.4 1.7 20 5.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM21797.1 - 1.8 9.0 6.5 52 4.4 0.0 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Kelch_6 PF13964.6 GAM21798.1 - 3.9e-10 39.6 3.9 0.0047 17.2 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAM21798.1 - 0.0075 15.8 1.6 1.4 8.5 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 GAM21798.1 - 2.2 8.3 5.4 6.9 6.8 0.5 3.0 3 0 0 3 3 3 0 Kelch motif SnoaL PF07366.12 GAM21799.1 - 0.0035 17.1 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Ank_2 PF12796.7 GAM21800.1 - 1.1e-07 32.3 4.0 0.09 13.4 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM21800.1 - 3.2e-05 24.0 2.0 91 4.1 0.0 8.2 9 0 0 9 9 9 0 Ankyrin repeat Ank_4 PF13637.6 GAM21800.1 - 0.001 19.6 1.3 4.3 8.0 0.0 5.5 4 2 2 6 6 6 1 Ankyrin repeats (many copies) CTP_transf_3 PF02348.19 GAM21800.1 - 0.029 14.3 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 Cytidylyltransferase DUF1955 PF09205.10 GAM21800.1 - 0.066 13.0 0.1 0.25 11.1 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Arm PF00514.23 GAM21801.1 - 0.0053 16.8 5.9 1.1 9.4 0.1 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAM21801.1 - 0.079 13.5 0.8 37 5.0 0.0 3.7 3 0 0 3 3 3 0 HEAT-like repeat CENP-U PF13097.6 GAM21801.1 - 6.1 6.8 18.9 2.1 8.3 7.4 2.5 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit SPX PF03105.19 GAM21801.1 - 7.4 6.4 25.8 0.035 14.0 8.7 2.2 2 0 0 2 2 2 0 SPX domain TMEM131_like PF12371.8 GAM21802.1 - 1.7e-16 60.2 21.3 2e-13 50.4 0.0 6.8 8 0 0 8 8 8 3 Transmembrane protein 131-like ASH PF15780.5 GAM21802.1 - 6.1e-09 36.0 4.8 0.038 14.2 0.0 5.9 6 0 0 6 6 6 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 GAM21802.1 - 2.9e-08 33.6 3.8 0.02 14.9 0.0 6.2 7 0 0 7 7 7 2 Protein of unknown function (DUF1573) Kelch_1 PF01344.25 GAM21803.1 - 6.9e-47 156.8 12.0 8.1e-09 34.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAM21803.1 - 1e-43 146.2 6.0 4e-08 33.3 0.0 6.5 3 2 3 6 6 6 6 Kelch motif Kelch_4 PF13418.6 GAM21803.1 - 4.9e-34 116.1 1.7 2.9e-07 30.4 0.0 6.6 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM21803.1 - 6.3e-21 74.2 0.0 0.0025 18.0 0.0 7.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM21803.1 - 1.6e-18 66.3 10.5 0.00096 19.1 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAM21803.1 - 4.2e-13 48.7 4.9 0.00018 21.3 0.1 6.5 6 0 0 6 6 6 3 Kelch motif zf-B_box PF00643.24 GAM21803.1 - 1.3e-06 28.4 4.7 2.4e-06 27.6 4.7 1.4 1 0 0 1 1 1 1 B-box zinc finger DUF3439 PF11921.8 GAM21803.1 - 0.017 15.1 8.4 0.048 13.6 8.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2085 PF09858.9 GAM21803.1 - 0.043 14.3 0.3 0.1 13.1 0.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) DUF4407 PF14362.6 GAM21803.1 - 0.21 10.9 7.5 0.92 8.8 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mucin PF01456.17 GAM21803.1 - 0.23 11.5 15.2 0.54 10.3 15.2 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF5085 PF16895.5 GAM21803.1 - 0.38 11.1 5.8 0.2 12.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5085) AAA_23 PF13476.6 GAM21803.1 - 5.7 7.4 12.7 2.7 8.5 0.3 3.4 3 0 0 3 3 3 0 AAA domain CKS PF01111.19 GAM21804.1 - 2.7e-32 110.8 0.1 3e-32 110.7 0.1 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit UPF0113_N PF17833.1 GAM21805.1 - 1.2e-29 102.6 1.8 1.9e-29 102.0 1.8 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 GAM21805.1 - 3.5e-21 75.2 0.0 6.9e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain Maelstrom PF13017.6 GAM21805.1 - 0.08 12.6 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 piRNA pathway germ-plasm component PUA PF01472.20 GAM21805.1 - 0.087 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 PUA domain Ribosomal_L36e PF01158.18 GAM21806.1 - 1.6e-31 108.4 3.5 1.8e-31 108.3 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DKCLD PF08068.12 GAM21806.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 DKCLD (NUC011) domain Thioredoxin PF00085.20 GAM21807.1 - 6.1e-17 61.5 0.0 1.3e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Pex14_N PF04695.13 GAM21807.1 - 0.00061 20.5 40.8 0.0068 17.1 27.2 2.4 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region FGF-BP1 PF06473.12 GAM21807.1 - 0.01 15.7 15.9 0.049 13.5 11.9 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Plasmodium_Vir PF05795.11 GAM21807.1 - 0.023 14.1 0.3 0.023 14.1 0.3 1.4 2 0 0 2 2 1 0 Plasmodium vivax Vir protein Thioredoxin_2 PF13098.6 GAM21807.1 - 0.025 15.0 0.0 0.025 15.0 0.0 2.1 2 0 0 2 2 1 0 Thioredoxin-like domain MecA PF05389.12 GAM21807.1 - 0.05 13.2 3.8 0.08 12.6 1.6 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) EPL1 PF10513.9 GAM21807.1 - 0.089 13.2 11.6 0.14 12.5 9.4 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like EOS1 PF12326.8 GAM21807.1 - 0.1 12.5 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 N-glycosylation protein DUF4366 PF14283.6 GAM21807.1 - 0.11 12.5 4.1 0.13 12.3 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Ctr PF04145.15 GAM21807.1 - 0.16 12.6 5.4 1.2 9.8 5.2 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Rxt3 PF08642.10 GAM21807.1 - 0.22 12.3 6.3 0.68 10.7 4.3 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 XRN_M PF17846.1 GAM21807.1 - 0.24 10.3 10.4 0.37 9.7 10.4 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Connexin PF00029.19 GAM21807.1 - 0.31 10.7 4.2 0.5 10.1 3.7 1.7 2 0 0 2 2 1 0 Connexin TFIIA PF03153.13 GAM21807.1 - 0.32 10.9 58.0 0.068 13.2 42.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 GAM21807.1 - 0.44 8.8 9.1 0.65 8.2 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GAM21807.1 - 0.71 8.6 19.4 0.66 8.7 17.6 1.7 2 0 0 2 2 2 0 Presenilin Gti1_Pac2 PF09729.9 GAM21807.1 - 0.78 9.8 11.1 0.14 12.2 7.5 1.6 2 0 0 2 2 2 0 Gti1/Pac2 family Baculo_PP31 PF05311.11 GAM21807.1 - 1.1 8.7 9.8 0.37 10.2 6.2 1.9 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Tim54 PF11711.8 GAM21807.1 - 1.2 7.8 17.5 0.024 13.5 10.3 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 OATP PF03137.20 GAM21807.1 - 1.2 7.3 5.9 0.67 8.2 3.7 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TERB2 PF15101.6 GAM21807.1 - 1.6 8.7 19.5 0.21 11.6 13.3 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 OAD_gamma PF04277.13 GAM21807.1 - 1.7 9.3 0.0 1.7 9.3 0.0 3.1 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain DUF5427 PF10310.9 GAM21807.1 - 1.7 7.5 19.2 0.013 14.4 10.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Peroxin-13_N PF04088.13 GAM21807.1 - 3.1 8.1 5.7 1.1 9.6 2.5 1.9 2 0 0 2 2 2 0 Peroxin 13, N-terminal region SLC12 PF03522.15 GAM21807.1 - 3.3 6.6 13.8 1.8 7.5 11.9 1.5 2 0 0 2 2 2 0 Solute carrier family 12 MDM10 PF12519.8 GAM21807.1 - 3.5 6.4 9.8 5.4 5.8 9.8 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 ALMT PF11744.8 GAM21807.1 - 3.5 6.4 7.6 5 5.8 7.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 GAM21807.1 - 3.6 5.6 13.9 1.1 7.3 10.8 1.6 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein CPSF100_C PF13299.6 GAM21807.1 - 3.9 7.6 12.8 0.81 9.8 8.8 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 GAM21807.1 - 4.8 6.1 9.2 1.5 7.7 6.5 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) PAT1 PF09770.9 GAM21807.1 - 4.9 5.3 39.5 0.16 10.2 28.5 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Serinc PF03348.15 GAM21807.1 - 4.9 6.0 4.6 2.2 7.1 2.2 1.6 2 0 0 2 2 2 0 Serine incorporator (Serinc) FAM176 PF14851.6 GAM21807.1 - 4.9 6.8 10.3 7.4 6.2 7.8 2.0 2 0 0 2 2 2 0 FAM176 family GRP PF07172.11 GAM21807.1 - 5.7 7.7 5.4 8.1 7.2 0.0 2.5 2 0 0 2 2 1 0 Glycine rich protein family RR_TM4-6 PF06459.12 GAM21807.1 - 6.2 6.6 18.8 0.75 9.6 14.1 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 GAM21807.1 - 6.8 5.8 5.8 11 5.2 5.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Arf PF00025.21 GAM21808.1 - 3.2e-65 218.8 0.1 3.7e-65 218.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM21808.1 - 1.4e-13 51.1 0.0 2.3e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM21808.1 - 6.8e-13 48.5 0.0 8.5e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAM21808.1 - 2.8e-09 36.7 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAM21808.1 - 3.4e-09 36.4 0.0 4.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 GAM21808.1 - 6.3e-09 35.5 0.4 1.1e-05 24.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 GAM21808.1 - 3.7e-05 23.8 0.0 0.00017 21.7 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase GST_C PF00043.25 GAM21809.1 - 4.7e-13 49.2 0.0 7.7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM21809.1 - 6.8e-12 45.6 0.0 1.3e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM21809.1 - 3.3e-11 43.2 0.2 1.4e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM21809.1 - 1.3e-08 35.2 0.0 6.4e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM21809.1 - 2e-08 34.4 0.0 5.8e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM21809.1 - 2.1e-08 34.1 0.3 6.2e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAM21809.1 - 0.0085 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Thiolase_N PF00108.23 GAM21810.1 - 3.1e-87 292.2 1.4 3.1e-87 292.2 1.4 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM21810.1 - 7e-45 151.7 1.8 4.4e-44 149.1 1.2 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAM21810.1 - 4.6e-06 26.4 0.2 0.00012 21.8 0.3 2.5 1 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM21810.1 - 0.032 14.3 0.3 11 6.1 0.0 3.0 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain DUF840 PF05801.11 GAM21810.1 - 0.088 12.9 0.1 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) HIRA_B PF09453.10 GAM21811.1 - 0.01 15.7 0.4 0.062 13.2 0.3 2.5 2 0 0 2 2 2 0 HIRA B motif Exonuc_VII_L PF02601.15 GAM21811.1 - 0.17 11.4 16.5 0.24 10.9 16.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PRKCSH PF07915.13 GAM21812.1 - 2.7e-12 47.5 0.1 2.7e-12 47.5 0.1 3.0 2 1 0 2 2 1 1 Glucosidase II beta subunit-like protein Zip PF02535.22 GAM21812.1 - 0.011 14.9 3.2 0.017 14.3 3.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter CIMR PF00878.18 GAM21812.1 - 0.033 14.2 0.1 0.076 13.1 0.1 1.5 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat CytochromB561_N PF09786.9 GAM21812.1 - 0.055 12.5 2.3 0.071 12.1 2.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal MMR1 PF08505.10 GAM21812.1 - 0.11 12.7 9.7 0.17 12.2 9.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 GAM21812.1 - 0.11 11.2 9.0 0.15 10.8 9.0 1.1 1 0 0 1 1 1 0 Presenilin FAM222A PF15258.6 GAM21812.1 - 0.24 10.5 10.4 0.36 9.9 10.4 1.3 1 0 0 1 1 1 0 Protein family of FAM222A GAGA_bind PF06217.12 GAM21812.1 - 0.56 10.5 9.0 0.81 9.9 9.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SLC12 PF03522.15 GAM21812.1 - 0.93 8.4 8.5 1.3 8.0 8.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SID-1_RNA_chan PF13965.6 GAM21812.1 - 1.7 6.9 4.8 2.4 6.5 4.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 GAM21812.1 - 2.9 7.9 5.7 5.4 7.0 5.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Phostensin PF13914.6 GAM21812.1 - 9.2 6.9 9.5 16 6.1 9.5 1.3 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region Ank_2 PF12796.7 GAM21813.1 - 7.9e-24 84.1 7.3 1.1e-06 29.1 1.3 5.3 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM21813.1 - 1e-17 64.2 7.8 7.1e-05 23.3 0.1 7.5 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM21813.1 - 4.1e-14 52.5 10.6 0.069 13.5 0.8 8.7 4 2 5 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM21813.1 - 6.8e-13 47.5 5.5 0.36 11.5 0.0 9.7 9 1 1 10 10 10 2 Ankyrin repeat Ank PF00023.30 GAM21813.1 - 1.1e-05 25.7 4.9 46 4.7 1.8 7.5 5 2 2 7 7 7 0 Ankyrin repeat Brr6_like_C_C PF10104.9 GAM21814.1 - 3.8e-37 127.0 3.4 6.5e-37 126.3 3.4 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF2014 PF09427.10 GAM21814.1 - 6.9 5.9 6.3 1.7 7.9 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2014) CHORD PF04968.12 GAM21815.1 - 1.2e-49 166.8 22.7 6.5e-25 87.6 6.5 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 GAM21815.1 - 2.6e-13 50.8 0.3 5.6e-13 49.7 0.3 1.6 1 0 0 1 1 1 1 CS domain BTK PF00779.19 GAM21815.1 - 1.7 8.5 15.9 0.34 10.8 1.3 3.5 3 1 0 3 3 3 0 BTK motif Kelch_1 PF01344.25 GAM21816.1 - 7.8e-22 76.6 8.2 2.6e-07 30.1 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 GAM21816.1 - 3e-19 68.6 15.7 5e-09 36.1 0.1 6.8 5 2 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 GAM21816.1 - 1.6e-18 66.4 14.9 5.9e-07 29.4 0.1 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM21816.1 - 3.9e-14 52.3 9.4 9e-05 22.4 0.1 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 GAM21816.1 - 3e-12 46.0 17.7 3.9e-05 23.4 0.0 7.0 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 GAM21816.1 - 2.4e-10 40.5 15.8 1.5e-07 31.5 0.0 7.1 7 2 0 7 7 7 2 Galactose oxidase, central domain F-box-like PF12937.7 GAM21816.1 - 4.5e-07 29.7 0.4 1e-06 28.5 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM21816.1 - 1e-05 25.2 2.2 2.3e-05 24.2 2.2 1.6 1 0 0 1 1 1 1 F-box domain Tir_receptor_N PF07490.11 GAM21816.1 - 0.31 10.8 3.1 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus IQCJ-SCHIP1 PF15157.6 GAM21816.1 - 0.36 10.7 12.2 6.9 6.5 0.6 3.1 3 0 0 3 3 3 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif SQS_PSY PF00494.19 GAM21817.1 - 3.2e-32 112.1 0.0 1e-29 103.9 0.0 2.1 1 1 0 1 1 1 1 Squalene/phytoene synthase DUF908 PF06012.12 GAM21818.1 - 0.04 13.3 6.0 0.07 12.5 6.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SOG2 PF10428.9 GAM21818.1 - 0.31 10.2 6.8 0.41 9.8 6.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Nucleo_P87 PF07267.11 GAM21818.1 - 1.6 7.5 14.5 2.3 7.0 14.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pex14_N PF04695.13 GAM21818.1 - 6.5 7.4 12.4 13 6.5 12.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NARP1 PF12569.8 GAM21819.1 - 3.5e-131 438.6 22.5 9.5e-117 391.0 13.7 3.4 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 GAM21819.1 - 5.1e-15 54.9 0.3 2.9 8.9 0.0 9.4 7 3 4 11 11 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21819.1 - 5e-10 38.7 22.6 9.8e-05 22.2 0.0 8.8 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM21819.1 - 5.3e-08 33.3 6.5 1.5 9.4 0.1 7.3 6 1 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM21819.1 - 1.9e-06 28.1 11.8 0.085 13.2 0.0 6.8 6 2 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM21819.1 - 2e-06 27.6 8.0 0.48 10.8 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM21819.1 - 6.8e-06 25.7 16.1 0.0024 17.6 0.0 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM21819.1 - 0.00021 21.4 3.3 2.4 8.8 0.1 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM21819.1 - 0.00054 20.6 3.0 40 5.0 0.3 5.5 4 2 2 6 6 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM21819.1 - 0.00059 19.3 2.9 1.6 8.0 0.3 3.8 3 1 1 4 4 4 2 MalT-like TPR region ANAPC3 PF12895.7 GAM21819.1 - 0.0012 19.0 19.2 0.17 12.1 3.2 5.9 5 1 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAM21819.1 - 0.0014 18.5 5.0 40 4.5 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM21819.1 - 0.011 16.3 11.6 4.2 8.2 0.1 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM21819.1 - 0.013 15.4 1.3 15 5.6 0.0 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat AnfO_nitrog PF09582.10 GAM21819.1 - 0.043 13.2 0.3 0.11 11.8 0.3 1.7 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) YfiO PF13525.6 GAM21819.1 - 0.084 12.6 5.0 0.11 12.1 0.1 3.5 3 1 1 4 4 4 0 Outer membrane lipoprotein TPR_9 PF13371.6 GAM21819.1 - 0.11 12.7 0.4 16 5.8 0.4 3.8 4 1 0 4 4 3 0 Tetratricopeptide repeat ATP13 PF12921.7 GAM21819.1 - 0.23 11.3 1.4 17 5.3 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ATPase expression Fis1_TPR_C PF14853.6 GAM21819.1 - 0.97 9.6 14.3 16 5.7 0.1 5.7 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat SRP_TPR_like PF17004.5 GAM21819.1 - 2.5 8.2 17.8 5.3 7.1 0.8 4.4 4 1 0 4 4 4 0 Putative TPR-like repeat PIF1 PF05970.14 GAM21820.1 - 7.1e-61 206.4 0.1 2.7e-46 158.4 0.1 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 GAM21820.1 - 1.6e-25 90.0 0.0 2.6e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM21820.1 - 7.9e-13 49.0 0.0 3.6e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM21820.1 - 1.9e-06 28.2 0.0 5.1e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAM21820.1 - 7.3e-05 22.4 0.0 0.0003 20.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF2075 PF09848.9 GAM21820.1 - 7.3e-05 22.2 0.3 0.00055 19.3 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 GAM21820.1 - 7.6e-05 22.7 0.1 0.00029 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.29 GAM21820.1 - 0.0002 21.2 0.1 0.19 11.5 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Herpes_Helicase PF02689.14 GAM21820.1 - 0.00022 19.3 0.0 0.036 12.0 0.0 2.2 2 0 0 2 2 2 2 Helicase T2SSE PF00437.20 GAM21820.1 - 0.00036 19.7 0.3 0.00057 19.0 0.3 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 GAM21820.1 - 0.00038 20.4 0.2 0.00085 19.3 0.1 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 GAM21820.1 - 0.00052 19.8 0.2 1.5 8.5 0.3 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 GAM21820.1 - 0.00057 19.8 3.7 0.0071 16.2 1.3 2.8 2 1 0 2 2 2 1 Helicase UvrD-helicase PF00580.21 GAM21820.1 - 0.0017 17.9 0.1 0.0083 15.7 0.1 2.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 GAM21820.1 - 0.002 17.6 0.1 0.0037 16.8 0.1 1.4 1 0 0 1 1 1 1 PhoH-like protein RsgA_GTPase PF03193.16 GAM21820.1 - 0.003 17.5 0.2 0.0061 16.5 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 GAM21820.1 - 0.004 17.2 0.0 0.016 15.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM21820.1 - 0.0048 17.3 0.0 0.0097 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 GAM21820.1 - 0.0059 16.0 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAM21820.1 - 0.0072 16.1 0.5 0.055 13.2 0.1 2.3 3 0 0 3 3 2 1 IstB-like ATP binding protein NTPase_1 PF03266.15 GAM21820.1 - 0.01 15.8 0.1 1.6 8.6 0.0 2.8 3 0 0 3 3 2 0 NTPase AAA PF00004.29 GAM21820.1 - 0.011 16.2 0.1 0.026 14.9 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 GAM21820.1 - 0.011 14.7 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 GAM21820.1 - 0.011 15.7 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 GAM21820.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_10 PF12846.7 GAM21820.1 - 0.013 14.4 0.1 0.029 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_11 PF13086.6 GAM21820.1 - 0.02 14.7 1.2 6.5 6.5 0.1 2.7 1 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 GAM21820.1 - 0.027 14.8 0.0 0.13 12.6 0.0 2.2 1 1 0 1 1 1 0 RNA helicase ATPase PF06745.13 GAM21820.1 - 0.041 13.2 2.0 0.17 11.2 0.1 2.6 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.26 GAM21820.1 - 0.042 13.5 0.7 0.085 12.6 0.1 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 GAM21820.1 - 0.049 13.3 0.1 0.33 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAM21820.1 - 0.068 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 GAM21820.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 GAM21820.1 - 0.12 12.9 0.1 0.45 11.0 0.0 1.9 1 1 0 2 2 1 0 ABC transporter PseudoU_synth_2 PF00849.22 GAM21821.1 - 9.1e-15 55.1 1.0 4.3e-14 52.9 0.0 2.6 2 2 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 GAM21821.1 - 2.3e-12 46.4 0.6 8.6e-12 44.6 0.2 2.3 1 1 1 2 2 2 1 S4 domain AAA_25 PF13481.6 GAM21821.1 - 0.015 14.8 0.0 0.043 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain S4_2 PF13275.6 GAM21821.1 - 0.017 14.9 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 S4 domain DUF5069 PF16798.5 GAM21821.1 - 0.032 14.4 0.0 0.095 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) FNIP PF05725.12 GAM21822.1 - 9.4e-56 185.8 4.3 5.6e-11 42.4 0.0 6.6 4 1 5 9 9 9 7 FNIP Repeat DUF1769 PF08588.10 GAM21822.1 - 0.0081 16.3 10.0 25 5.2 0.1 6.3 6 2 1 7 7 7 2 Protein of unknown function (DUF1769) COX6C PF02937.15 GAM21823.1 - 0.052 13.7 0.1 19 5.4 0.0 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc DEP PF00610.21 GAM21824.1 - 2.1e-37 127.0 1.9 2.5e-18 65.9 0.1 2.6 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.25 GAM21825.1 - 3.1e-63 213.6 0.0 5.2e-63 212.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21825.1 - 5.5e-44 150.4 0.0 8.9e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM21825.1 - 0.0019 17.6 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Prominin PF05478.11 GAM21825.1 - 8.9 4.1 7.4 12 3.7 7.4 1.1 1 0 0 1 1 1 0 Prominin GNT-I PF03071.15 GAM21827.1 - 8.9e-10 37.9 1.7 1e-09 37.7 1.0 1.4 2 0 0 2 2 2 1 GNT-I family UBD PF16455.5 GAM21827.1 - 0.0022 18.2 0.0 0.0077 16.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-binding domain Tox-ODYAM1 PF15642.6 GAM21827.1 - 0.23 10.4 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Integrin_beta PF00362.18 GAM21828.1 - 0.018 14.7 0.3 0.85 9.2 0.2 2.5 2 1 1 3 3 3 0 Integrin beta chain VWA domain FNIP PF05725.12 GAM21829.1 - 1e-25 89.6 18.6 3.3e-08 33.6 0.0 5.3 5 1 0 5 5 5 4 FNIP Repeat LRR_4 PF12799.7 GAM21829.1 - 1.9 9.0 6.5 1.6 9.2 0.1 3.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) RabGAP-TBC PF00566.18 GAM21831.1 - 5.5e-46 156.9 3.6 2.8e-45 154.6 3.6 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_1 PF00036.32 GAM21831.1 - 2.7e-12 45.3 3.0 1.4e-05 24.3 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GAM21831.1 - 3.1e-11 42.2 2.5 4.6e-05 23.0 0.2 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAM21831.1 - 2.1e-10 39.6 3.2 0.00015 21.1 0.4 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAM21831.1 - 3.8e-08 33.6 7.7 0.0014 19.0 0.8 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 GAM21831.1 - 0.0007 19.4 6.7 0.074 12.9 0.5 3.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 GAM21831.1 - 0.024 14.9 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain DUF5526 PF17664.1 GAM21831.1 - 0.089 12.4 3.4 0.06 12.9 0.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5526) Arf PF00025.21 GAM21832.1 - 1.1e-70 236.6 2.0 1.3e-70 236.4 2.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM21832.1 - 8.9e-14 51.7 0.1 1.3e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAM21832.1 - 2.6e-12 46.6 3.5 2.2e-07 30.4 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GAM21832.1 - 3.1e-12 46.4 0.1 3.7e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAM21832.1 - 9.9e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM21832.1 - 2.1e-08 33.8 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM21832.1 - 4.1e-07 30.1 0.0 6.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 GAM21832.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 GAM21832.1 - 0.015 14.9 0.0 0.043 13.4 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 GAM21832.1 - 0.022 14.8 0.4 0.041 13.9 0.3 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 GAM21832.1 - 0.07 12.7 0.3 0.22 11.0 0.3 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF829 PF05705.14 GAM21833.1 - 2e-39 135.9 1.3 6.4e-39 134.3 1.3 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) HTH_Tnp_IS1 PF12759.7 GAM21833.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 InsA C-terminal domain Ribosomal_L38e PF01781.18 GAM21834.1 - 7.2e-28 96.5 2.0 8.2e-28 96.3 2.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF5630 PF18632.1 GAM21834.1 - 0.07 12.4 0.0 0.077 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5630) FmiP_Thoc5 PF09766.9 GAM21835.1 - 4.8e-41 141.3 10.1 6.6e-21 75.0 8.0 2.0 1 1 1 2 2 2 2 Fms-interacting protein/Thoc5 DUF4164 PF13747.6 GAM21835.1 - 0.051 13.8 12.3 0.051 13.9 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Baculo_PEP_C PF04513.12 GAM21835.1 - 0.2 11.7 5.9 0.064 13.3 2.0 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CREPT PF16566.5 GAM21835.1 - 2.8 8.1 9.8 11 6.2 1.9 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ADIP PF11559.8 GAM21835.1 - 3.4 7.8 11.0 11 6.1 0.7 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GvpG PF05120.12 GAM21835.1 - 4.1 7.5 6.6 20 5.3 0.1 3.0 3 1 0 3 3 3 0 Gas vesicle protein G OB_NTP_bind PF07717.16 GAM21836.1 - 2.6e-17 62.9 0.0 7.2e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GAM21836.1 - 2.8e-17 62.9 0.0 2.8e-17 62.9 0.0 2.6 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAM21836.1 - 1.5e-14 54.2 0.0 4.4e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM21836.1 - 2.1e-11 43.9 0.6 7.7e-11 42.1 0.1 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase RWD PF05773.22 GAM21836.1 - 8.4e-09 35.7 0.0 4.1e-08 33.5 0.0 2.3 1 1 0 1 1 1 1 RWD domain AAA_22 PF13401.6 GAM21836.1 - 1.6e-05 25.2 0.5 8.4e-05 22.9 0.5 2.2 1 1 0 1 1 1 1 AAA domain DND1_DSRM PF14709.7 GAM21836.1 - 0.00013 22.1 0.1 0.00046 20.4 0.1 2.0 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_19 PF13245.6 GAM21836.1 - 0.0038 17.6 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain dsRBD2 PF17842.1 GAM21836.1 - 0.0097 16.1 0.1 0.0097 16.1 0.1 4.1 6 0 0 6 6 5 1 Double-stranded RNA binding domain 2 AAA_16 PF13191.6 GAM21836.1 - 0.031 14.7 0.2 0.72 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 GAM21836.1 - 0.042 12.9 1.0 0.065 12.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Tn916-Xis PF09035.10 GAM21836.1 - 0.081 13.1 0.1 25 5.2 0.0 2.7 1 1 1 2 2 2 0 Excisionase from transposon Tn916 AAA_29 PF13555.6 GAM21836.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvA_C PF07499.13 GAM21836.1 - 0.14 12.7 0.0 0.52 10.8 0.0 2.0 1 0 0 1 1 1 0 RuvA, C-terminal domain dsrm PF00035.26 GAM21836.1 - 0.32 11.7 1.4 0.72 10.6 0.1 2.4 2 0 0 2 2 1 0 Double-stranded RNA binding motif FtsK_SpoIIIE PF01580.18 GAM21836.1 - 0.61 9.4 3.4 1.3 8.3 0.0 2.9 4 0 0 4 4 4 0 FtsK/SpoIIIE family ER_lumen_recept PF00810.18 GAM21837.1 - 0.057 14.2 1.9 0.24 12.2 0.2 2.6 3 0 0 3 3 3 0 ER lumen protein retaining receptor DUF4381 PF14316.6 GAM21837.1 - 0.16 12.2 1.7 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Consortin_C PF15281.6 GAM21837.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.5 4 0 0 4 4 4 0 Consortin C-terminus Rubis-subs-bind PF09273.11 GAM21837.1 - 1.2 9.9 9.4 0.053 14.2 2.7 2.1 2 1 0 2 2 2 0 Rubisco LSMT substrate-binding Secretin_N_2 PF07655.13 GAM21837.1 - 3.5 8.2 16.6 1.8 9.2 9.2 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain Ribosomal_L22 PF00237.19 GAM21838.1 - 1.8e-19 69.9 0.0 4.6e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Mucin PF01456.17 GAM21838.1 - 0.13 12.3 11.7 0.18 11.8 11.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 GAM21838.1 - 0.51 8.4 7.3 0.65 8.1 7.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus LIM PF00412.22 GAM21839.1 - 1.3e-10 41.3 5.5 2.6e-10 40.4 5.5 1.5 1 0 0 1 1 1 1 LIM domain Dymeclin PF09742.9 GAM21840.1 - 8.4e-77 259.0 22.0 1e-76 258.7 22.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 GAM21840.1 - 0.5 8.4 22.7 2 6.4 22.7 1.8 1 1 0 1 1 1 0 High-temperature-induced dauer-formation protein Ada3 PF10198.9 GAM21842.1 - 2.1e-12 47.3 10.7 2.1e-12 47.3 10.7 2.2 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 PH PF00169.29 GAM21843.1 - 1.9e-06 28.3 4.1 7e-06 26.5 4.1 2.0 1 1 0 1 1 1 1 PH domain PH_13 PF16652.5 GAM21843.1 - 0.004 17.0 0.1 0.0091 15.8 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 GAM21843.1 - 0.0074 16.6 0.7 0.0074 16.6 0.7 2.1 2 1 0 2 2 2 1 Pleckstrin homology domain Ribosomal_60s PF00428.19 GAM21843.1 - 1.2 9.8 5.0 7.4 7.2 1.3 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chorion_2 PF03964.15 GAM21843.1 - 6.5 7.6 5.9 22 6.0 0.5 2.6 2 0 0 2 2 2 0 Chorion family 2 IF4E PF01652.18 GAM21844.1 - 8.3e-52 175.2 2.2 1.1e-51 174.7 2.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Tir_receptor_C PF07489.11 GAM21844.1 - 0.36 10.8 4.2 0.53 10.2 4.2 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus GST_C PF00043.25 GAM21845.1 - 2e-12 47.1 0.0 3.5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM21845.1 - 9.2e-12 45.1 1.6 1.5e-10 41.3 0.1 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM21845.1 - 1.4e-11 44.4 0.5 2.5e-11 43.6 0.5 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM21845.1 - 2.5e-10 40.6 0.0 5.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM21845.1 - 3.2e-10 40.2 0.0 7.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM21845.1 - 5.6e-10 39.1 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Malic_M PF03949.15 GAM21846.1 - 2.8e-101 338.1 0.0 3.8e-101 337.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAM21846.1 - 1.2e-69 233.8 0.0 2.9e-69 232.5 0.0 1.6 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain DUF4848 PF16140.5 GAM21847.1 - 0.32 10.5 2.1 0.35 10.4 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4848) SDA1 PF05285.12 GAM21847.1 - 3 7.2 13.5 6.3 6.1 13.5 1.5 1 0 0 1 1 1 0 SDA1 2-Hacid_dh_C PF02826.19 GAM21849.1 - 5.9e-49 165.8 0.0 1.3e-48 164.7 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM21849.1 - 9.3e-35 119.2 0.0 1.2e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 GAM21849.1 - 0.0028 17.4 0.1 2.2 8.1 0.0 2.8 2 0 0 2 2 2 2 ACT domain NAD_binding_2 PF03446.15 GAM21849.1 - 0.0082 16.3 0.1 0.025 14.7 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 GAM21849.1 - 0.028 14.9 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain Oxidored_nitro PF00148.19 GAM21849.1 - 0.059 12.1 0.0 0.48 9.1 0.0 2.0 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase PAP2 PF01569.21 GAM21850.1 - 1.3e-10 41.2 6.0 1.3e-10 41.2 6.0 2.7 3 0 0 3 3 3 1 PAP2 superfamily WD40 PF00400.32 GAM21851.1 - 1e-18 67.3 9.5 9.8e-05 23.1 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-RING_UBOX PF13445.6 GAM21851.1 - 4e-09 36.3 8.8 1.8e-08 34.3 8.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAM21851.1 - 1e-07 31.7 4.8 2.2e-07 30.6 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM21851.1 - 1.2e-07 31.4 10.6 1.2e-07 31.4 10.6 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 GAM21851.1 - 7.1e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like zf-RING_5 PF14634.6 GAM21851.1 - 9.2e-06 25.5 9.5 9.2e-06 25.5 9.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAM21851.1 - 1.2e-05 25.1 9.8 1.2e-05 25.1 9.8 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAM21851.1 - 3.1e-05 24.0 12.2 7.8e-05 22.8 12.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GAM21851.1 - 4.7e-05 23.6 10.2 0.00011 22.4 10.2 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAM21851.1 - 0.0002 21.1 7.5 0.00063 19.6 7.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 F-box PF00646.33 GAM21851.1 - 0.00031 20.5 0.1 0.00063 19.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain zf-RING_10 PF16685.5 GAM21851.1 - 0.00087 19.4 5.5 0.00087 19.4 5.5 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 ANAPC4_WD40 PF12894.7 GAM21851.1 - 0.0012 19.1 0.0 0.57 10.5 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM21851.1 - 0.022 13.4 1.1 1.8 7.1 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 zf-ANAPC11 PF12861.7 GAM21851.1 - 0.051 13.6 2.7 0.12 12.4 2.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAM21851.1 - 0.056 13.3 3.4 0.18 11.6 3.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PQQ_2 PF13360.6 GAM21851.1 - 0.14 11.7 0.1 5.2 6.6 0.1 2.2 2 0 0 2 2 2 0 PQQ-like domain zf-RING_6 PF14835.6 GAM21851.1 - 0.26 11.2 3.5 0.62 10.0 3.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GAM21851.1 - 1.8 8.9 8.0 4.3 7.7 8.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain ATP-synt PF00231.19 GAM21852.1 - 1.2e-57 195.8 0.3 1.4e-57 195.6 0.3 1.0 1 0 0 1 1 1 1 ATP synthase Proteasome PF00227.26 GAM21853.1 - 4.5e-47 160.0 0.1 5.1e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit VPS9 PF02204.18 GAM21854.1 - 6.2e-14 52.1 0.8 1.4e-13 50.9 0.8 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain TMEM144 PF07857.12 GAM21856.1 - 8.4e-86 288.0 15.0 9.6e-86 287.8 15.0 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 GAM21856.1 - 6.1e-11 42.2 4.9 6.1e-11 42.2 4.9 3.3 2 2 2 4 4 4 1 Sugar transport protein DMT_YdcZ PF04657.13 GAM21856.1 - 1.9 8.8 27.8 0.046 14.0 14.5 2.6 2 1 0 2 2 2 0 Putative inner membrane exporter, YdcZ Ank_3 PF13606.6 GAM21857.1 - 0.012 16.1 7.7 3.4e+02 2.4 0.0 9.1 12 0 0 12 12 12 0 Ankyrin repeat SAM_Exu PF18609.1 GAM21857.1 - 0.097 12.8 0.0 0.66 10.1 0.0 2.4 2 0 0 2 2 2 0 Exuperantia SAM-like domain Lyase_1 PF00206.20 GAM21858.1 - 2.1e-116 388.7 0.0 2.9e-116 388.2 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 GAM21858.1 - 5.6e-26 90.7 0.1 1.7e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 Fumarase C C-terminus LSM PF01423.22 GAM21859.1 - 1.6e-14 53.4 0.5 2.6e-14 52.7 0.5 1.4 1 0 0 1 1 1 1 LSM domain fragilysinNterm PF16376.5 GAM21859.1 - 0.00093 19.0 0.5 0.001 18.8 0.5 1.2 1 0 0 1 1 1 1 N-terminal domain of fragilysin SM-ATX PF14438.6 GAM21859.1 - 0.034 14.3 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Cullin_binding PF03556.15 GAM21860.1 - 8.3e-31 106.9 0.6 8.3e-31 106.9 0.6 1.7 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 GAM21860.1 - 3.1e-11 42.9 0.0 7.3e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 GAM21860.1 - 0.015 15.0 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 TAP C-terminal domain p25-alpha PF05517.12 GAM21860.1 - 0.062 13.5 1.3 1 9.5 0.4 2.3 1 1 1 2 2 2 0 p25-alpha Kelch_6 PF13964.6 GAM21861.1 - 2e-14 53.3 1.5 5.5e-07 29.7 0.1 4.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 GAM21861.1 - 6.6e-09 35.6 4.5 0.00011 22.2 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM21861.1 - 0.00026 20.5 2.8 0.91 9.2 0.1 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 GAM21861.1 - 0.05 13.6 0.5 0.05 13.6 0.5 2.8 3 0 0 3 3 3 0 Kelch motif Blt1 PF12754.7 GAM21861.1 - 1.5 9.2 3.6 4.7 7.5 0.4 2.2 2 0 0 2 2 2 0 Blt1 N-terminal domain NYD-SP28 PF14772.6 GAM21861.1 - 3.6 7.7 6.6 1.7 8.8 0.3 3.0 3 0 0 3 3 3 0 Sperm tail Phosphoesterase PF04185.14 GAM21862.1 - 8.8e-35 120.5 6.1 3.1e-34 118.7 1.7 2.8 1 1 1 2 2 2 1 Phosphoesterase family DUF273 PF03314.14 GAM21862.1 - 0.14 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Kelch_6 PF13964.6 GAM21863.1 - 3.5e-20 71.5 4.3 0.00017 21.8 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 GAM21863.1 - 8.2e-10 38.5 5.2 0.00051 20.0 0.0 4.0 4 0 0 4 4 3 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM21863.1 - 4.1e-06 26.3 5.4 0.22 11.1 0.1 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 GAM21863.1 - 1.2e-05 25.0 5.7 0.15 12.1 0.1 4.4 5 0 0 5 5 4 2 Kelch motif Kelch_5 PF13854.6 GAM21863.1 - 0.00089 19.2 9.5 0.11 12.6 0.2 3.4 3 0 0 3 3 3 2 Kelch motif NYD-SP28 PF14772.6 GAM21863.1 - 0.0016 18.5 14.2 0.3 11.1 0.1 5.1 5 0 0 5 5 5 2 Sperm tail Kelch_3 PF13415.6 GAM21863.1 - 0.0055 17.0 7.9 0.45 10.9 0.2 5.4 5 1 1 6 6 6 1 Galactose oxidase, central domain PGAP1 PF07819.13 GAM21863.1 - 0.0073 16.1 0.3 0.027 14.2 0.3 2.0 1 0 0 1 1 1 1 PGAP1-like protein MS_channel PF00924.18 GAM21863.1 - 0.013 15.0 3.6 1.5 8.3 0.0 2.8 3 0 0 3 3 3 0 Mechanosensitive ion channel DUF3268 PF11672.8 GAM21863.1 - 0.028 14.8 0.2 6.9 7.0 0.0 2.8 2 0 0 2 2 2 0 zinc-finger-containing domain DUF2383 PF09537.10 GAM21863.1 - 0.031 14.6 1.2 7.3 7.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) RRT14 PF17075.5 GAM21863.1 - 0.058 13.5 4.6 0.87 9.7 0.5 2.6 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 HTH_AsnC-type PF13404.6 GAM21863.1 - 0.079 12.8 0.1 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DHR10 PF18595.1 GAM21863.1 - 0.21 11.6 10.2 2 8.5 0.1 3.5 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain LBP_M PF17385.2 GAM21863.1 - 0.27 10.7 1.8 2.3 7.7 0.3 2.5 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase central domain Calreticulin PF00262.18 GAM21863.1 - 0.4 9.5 8.1 0.91 8.3 1.7 2.4 2 0 0 2 2 2 0 Calreticulin family TRADD_N PF09034.10 GAM21863.1 - 1.1 9.4 7.1 2.2 8.3 0.6 2.9 2 0 0 2 2 2 0 TRADD, N-terminal domain ELMO_CED12 PF04727.13 GAM21864.1 - 1.4e-25 90.4 0.7 4.4e-25 88.8 0.1 2.2 2 0 0 2 2 2 1 ELMO/CED-12 family Methyltransf_2 PF00891.18 GAM21864.1 - 0.091 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Pkinase PF00069.25 GAM21866.1 - 3.5e-69 233.1 0.1 4.7e-69 232.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21866.1 - 9.6e-49 166.0 0.1 1.4e-48 165.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 GAM21866.1 - 2.4e-21 76.2 0.2 5.2e-21 75.1 0.2 1.6 1 0 0 1 1 1 1 PH domain PBD PF00786.28 GAM21866.1 - 3.2e-15 56.2 0.1 7.3e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 GAM21866.1 - 1.5e-05 24.0 0.0 3.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM21866.1 - 0.00018 20.6 1.6 0.00038 19.5 1.6 1.4 1 1 0 1 1 1 1 Haspin like kinase domain PH_11 PF15413.6 GAM21866.1 - 0.00043 20.7 5.3 0.0029 18.0 2.3 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.6 GAM21866.1 - 0.00082 18.8 0.2 0.0092 15.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like PH_17 PF18012.1 GAM21866.1 - 0.001 18.7 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF1491 PF07372.12 GAM21866.1 - 0.027 14.8 0.0 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) PH_9 PF15410.6 GAM21866.1 - 0.041 14.2 0.1 1.6 9.1 0.1 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain DUF1356 PF07092.12 GAM21866.1 - 0.051 12.8 0.2 0.076 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) PH_8 PF15409.6 GAM21866.1 - 0.052 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Glycogen_syn PF05693.13 GAM21867.1 - 4.1e-270 897.8 0.0 5.1e-270 897.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 GAM21867.1 - 4e-05 23.4 1.6 5.1e-05 23.1 0.6 1.7 1 1 1 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GAM21867.1 - 5.6e-05 22.7 0.0 0.0012 18.4 0.0 2.6 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAM21867.1 - 0.00081 19.4 0.1 0.0016 18.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAM21867.1 - 0.0031 17.9 0.1 0.011 16.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 GAM21867.1 - 0.0069 16.8 0.0 0.22 11.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Pkinase PF00069.25 GAM21868.1 - 2.2e-77 260.0 0.0 4.9e-77 258.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM21868.1 - 3.3e-43 147.8 0.0 3.3e-43 147.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.19 GAM21868.1 - 4.4e-16 58.4 0.0 8e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 GAM21868.1 - 2.5e-06 27.1 0.0 5.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAM21868.1 - 3e-05 23.2 7.3 3e-05 23.2 7.3 3.0 3 1 0 3 3 3 1 Haspin like kinase domain RIO1 PF01163.22 GAM21868.1 - 4.5e-05 23.1 0.4 0.0001 22.0 0.4 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAM21868.1 - 0.00017 21.6 0.0 0.0032 17.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM21868.1 - 0.00065 19.1 0.1 0.002 17.5 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family UBA_2 PF08587.11 GAM21868.1 - 0.0037 17.4 0.2 0.011 15.9 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) UBA_3 PF09288.10 GAM21868.1 - 0.19 11.6 0.1 0.51 10.2 0.1 1.7 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Laminin_EGF PF00053.24 GAM21869.1 - 0.081 13.1 31.8 0.13 12.4 7.9 3.5 2 1 1 3 3 3 0 Laminin EGF domain UPF0172 PF03665.13 GAM21870.1 - 4.5e-50 170.4 0.1 5e-50 170.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 GAM21870.1 - 5.2e-05 23.2 0.1 7.8e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3689 PF12463.8 GAM21871.1 - 6.5e-22 78.2 4.6 3.8e-19 69.1 1.0 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF3689) BAR PF03114.18 GAM21872.1 - 3.5e-10 39.9 2.6 3.5e-10 39.9 2.6 1.8 2 0 0 2 2 2 1 BAR domain DnaJ PF00226.31 GAM21872.1 - 0.005 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Epimerase PF01370.21 GAM21873.1 - 8.1e-11 41.8 0.1 9.9e-10 38.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM21873.1 - 6.3e-05 22.9 0.0 9.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 GAM21873.1 - 0.00033 20.2 0.0 0.00056 19.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 GAM21873.1 - 0.0017 18.0 0.1 0.0049 16.5 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family DXP_reductoisom PF02670.16 GAM21873.1 - 0.011 16.5 0.0 0.03 15.1 0.0 1.8 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_2 PF03446.15 GAM21873.1 - 0.012 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 GAM21873.1 - 0.034 13.6 0.3 0.3 10.4 0.0 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 GAM21873.1 - 0.039 14.5 0.0 0.097 13.3 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 GAM21873.1 - 0.054 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain ALG11_N PF15924.5 GAM21874.1 - 1.2e-88 296.7 1.0 1.8e-88 296.1 1.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 GAM21874.1 - 1.1e-27 96.7 0.2 2.8e-27 95.3 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAM21874.1 - 6.8e-12 46.0 0.0 1.7e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF2183 PF09949.9 GAM21874.1 - 0.031 14.6 0.1 4.4 7.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2183) Ndc1_Nup PF09531.10 GAM21874.1 - 8.3 5.0 9.0 17 4.0 9.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BRX PF08381.11 GAM21875.1 - 0.048 13.0 0.3 0.13 11.6 0.1 1.8 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 IRS PF02174.17 GAM21875.1 - 0.072 13.0 1.5 0.16 11.8 0.9 1.9 2 0 0 2 2 2 0 PTB domain (IRS-1 type) FtsL PF04999.13 GAM21875.1 - 6.2 6.9 12.0 15 5.7 12.0 1.6 1 0 0 1 1 1 0 Cell division protein FtsL EBP PF05241.12 GAM21876.1 - 4.7e-42 143.4 12.1 5.4e-42 143.2 12.1 1.1 1 0 0 1 1 1 1 Emopamil binding protein Presenilin PF01080.17 GAM21876.1 - 8.7 5.0 11.8 0.16 10.7 1.0 2.1 2 0 0 2 2 2 0 Presenilin DUF2721 PF11026.8 GAM21876.1 - 9 6.2 10.5 0.73 9.7 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Paf1 PF03985.13 GAM21877.1 - 1.4e-49 169.3 7.3 1.4e-49 169.3 7.3 3.1 1 1 2 3 3 3 1 Paf1 Macoilin PF09726.9 GAM21877.1 - 1.3 7.5 42.0 0.38 9.3 34.3 2.4 2 0 0 2 2 2 0 Macoilin family CAML PF14963.6 GAM21877.1 - 9.1 6.3 14.9 25 4.9 14.9 1.8 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand BAAT_C PF08840.11 GAM21878.1 - 8e-05 22.7 0.0 0.0081 16.1 0.0 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 GAM21878.1 - 0.0011 18.6 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAM21878.1 - 0.0034 16.7 0.1 0.013 14.8 0.0 1.8 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Orn_Arg_deC_N PF02784.16 GAM21879.1 - 1.5e-78 263.6 0.0 2e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 GAM21879.1 - 3.3e-17 62.5 0.0 6.9e-17 61.5 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 GAM21879.1 - 0.00052 19.5 0.0 0.00088 18.8 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF5448 PF17526.2 GAM21879.1 - 0.017 15.3 0.0 0.059 13.6 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5448) Folliculin_C PF16692.5 GAM21880.1 - 5.1e-55 186.6 0.0 8.1e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Folliculin C-terminal domain Folliculin PF11704.8 GAM21880.1 - 7.5e-39 133.5 0.0 3.5e-38 131.4 0.0 2.0 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Cyt_c_ox_IV PF12270.8 GAM21881.1 - 0.016 15.3 0.3 0.017 15.2 0.3 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF5488 PF17590.2 GAM21881.1 - 0.065 13.0 0.4 0.075 12.8 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5488) Ran_BP1 PF00638.18 GAM21882.1 - 2.7e-44 150.3 0.4 3.8e-44 149.9 0.4 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 GAM21882.1 - 0.012 15.5 0.7 0.15 12.1 0.7 2.1 1 1 0 1 1 1 0 WH1 domain MRI PF15325.6 GAM21882.1 - 2.2 9.4 7.7 0.61 11.2 3.7 2.1 1 1 1 2 2 2 0 Modulator of retrovirus infection SH3_9 PF14604.6 GAM21883.1 - 3e-18 65.4 0.1 6.2e-18 64.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM21883.1 - 7.4e-14 51.1 0.1 1.5e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 GAM21883.1 - 8.4e-14 51.6 0.1 4.4e-13 49.3 0.1 2.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 GAM21883.1 - 2.6e-13 49.4 0.0 6.3e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.16 GAM21883.1 - 0.00012 22.2 1.3 0.00012 22.2 1.3 3.7 4 1 1 5 5 5 1 Hr1 repeat WDCP PF15390.6 GAM21883.1 - 0.77 8.1 19.6 0.083 11.3 13.6 1.9 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family FlaC_arch PF05377.11 GAM21883.1 - 0.8 10.1 9.7 4.2 7.8 0.2 4.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Spore_YtfJ PF09579.10 GAM21884.1 - 0.98 9.6 5.2 2.1 8.6 5.2 1.5 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Lectin_leg-like PF03388.13 GAM21885.1 - 1.4e-52 178.4 1.4 1.4e-52 178.4 1.4 1.6 2 0 0 2 2 2 1 Legume-like lectin family Baculo_p24 PF05073.12 GAM21885.1 - 0.036 13.8 0.5 0.036 13.8 0.5 3.0 3 1 0 3 3 3 0 Baculovirus P24 capsid protein Presenilin PF01080.17 GAM21885.1 - 0.24 10.1 17.9 0.39 9.4 17.9 1.3 1 0 0 1 1 1 0 Presenilin DUF2120 PF09893.9 GAM21885.1 - 0.28 11.3 9.9 0.18 11.9 0.4 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) PAT1 PF09770.9 GAM21885.1 - 0.29 9.4 35.3 0.41 8.9 35.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF948 PF06103.11 GAM21885.1 - 1 9.7 8.6 1.9 8.8 1.6 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Serinc PF03348.15 GAM21885.1 - 4.1 6.2 6.0 0.89 8.4 1.8 1.9 2 0 0 2 2 2 0 Serine incorporator (Serinc) ATP11 PF06644.11 GAM21886.1 - 2.3e-37 129.3 1.1 2.3e-37 129.3 1.1 1.5 2 0 0 2 2 2 1 ATP11 protein YhhN PF07947.14 GAM21887.1 - 9.1e-33 113.4 19.4 1.3e-32 112.9 19.4 1.2 1 0 0 1 1 1 1 YhhN family DUF2070 PF09843.9 GAM21887.1 - 0.68 8.1 21.7 0.82 7.9 21.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4175 PF13779.6 GAM21887.1 - 0.96 7.3 1.7 1.5 6.7 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tmemb_18A PF09771.9 GAM21887.1 - 1.5 9.3 0.0 1.5 9.3 0.0 3.4 1 1 1 3 3 3 0 Transmembrane protein 188 Amidase PF01425.21 GAM21888.1 - 1.4e-89 301.1 0.0 2.9e-89 300.1 0.0 1.5 1 0 0 1 1 1 1 Amidase PRCC PF10253.9 GAM21888.1 - 2.3 8.9 9.9 6.2 7.6 10.1 1.6 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting VASt PF16016.5 GAM21889.1 - 2.1e-26 93.2 0.7 5.5e-26 91.8 0.7 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GAM21889.1 - 5.8e-19 68.0 0.2 1.5e-18 66.8 0.2 1.7 1 0 0 1 1 1 1 GRAM domain Ras PF00071.22 GAM21890.1 - 1.7e-58 196.8 0.3 1.9e-58 196.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM21890.1 - 8.9e-32 109.8 0.1 1.3e-31 109.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM21890.1 - 2.1e-11 43.6 0.0 2.7e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM21890.1 - 0.00045 19.6 0.0 0.0007 19.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM21890.1 - 0.0033 17.5 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 GAM21890.1 - 0.0056 16.5 0.0 0.0068 16.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 GAM21890.1 - 0.033 14.1 0.1 9.5 6.1 0.0 2.3 1 1 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 GAM21890.1 - 0.045 13.3 0.0 0.087 12.3 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Ribosomal_L37 PF08561.10 GAM21892.1 - 0.054 14.0 2.0 0.24 12.0 2.0 1.8 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 Proteasome PF00227.26 GAM21893.1 - 1.1e-54 184.9 0.0 1.9e-54 184.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM21893.1 - 2.3e-12 46.4 0.1 3.8e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5018 PF16410.5 GAM21893.1 - 0.012 14.3 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) DUF4916 PF16262.5 GAM21893.1 - 0.021 14.3 0.1 0.036 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) PH_5 PF15405.6 GAM21893.1 - 0.074 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Rho_GDI PF02115.17 GAM21894.1 - 1.4e-54 184.9 0.1 1.5e-54 184.7 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor MBF1 PF08523.10 GAM21894.1 - 0.085 13.3 0.2 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 Multiprotein bridging factor 1 BppU_N PF10651.9 GAM21894.1 - 0.1 12.3 0.1 1.9 8.2 0.0 2.5 2 1 0 2 2 2 0 BppU N-terminal domain Ssu72 PF04722.13 GAM21895.1 - 5.2e-72 241.4 0.0 5.9e-72 241.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.21 GAM21895.1 - 0.092 13.1 0.1 8.2 6.8 0.0 2.3 1 1 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase DUF1754 PF08555.10 GAM21896.1 - 9.2e-09 36.0 17.7 1.3e-07 32.3 13.0 2.7 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Anti-adapt_IraP PF10796.9 GAM21896.1 - 0.016 15.8 0.3 0.031 14.8 0.3 1.5 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein ESM4 PF15952.5 GAM21896.1 - 0.063 13.7 5.0 0.079 13.4 5.0 1.0 1 0 0 1 1 1 0 Enhancer of split M4 family SpoIIP PF07454.11 GAM21896.1 - 0.081 12.4 5.8 0.087 12.3 5.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF3824 PF12868.7 GAM21896.1 - 3.1 8.5 8.0 0.6 10.8 4.6 1.5 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) SPRY PF00622.28 GAM21897.1 - 1e-09 38.6 0.2 4.6e-09 36.4 0.2 2.1 2 0 0 2 2 2 1 SPRY domain zf-RING_2 PF13639.6 GAM21897.1 - 1.2e-07 31.9 5.4 1.2e-07 31.9 5.4 3.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 GAM21897.1 - 0.00011 21.9 7.3 0.00011 21.9 7.3 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAM21897.1 - 0.00014 21.7 4.9 0.00014 21.7 4.9 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FOXP-CC PF16159.5 GAM21897.1 - 0.00034 21.2 1.0 0.00089 19.8 1.0 1.7 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 GAM21897.1 - 0.037 14.2 2.6 0.084 13.0 2.6 1.6 1 0 0 1 1 1 0 Aberrant zinc-finger IBR PF01485.21 GAM21897.1 - 0.046 13.9 3.1 0.051 13.8 1.0 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_9 PF16293.5 GAM21897.1 - 0.32 10.9 2.4 1.8 8.4 0.1 2.6 2 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-RING-like PF08746.11 GAM21897.1 - 1.2 9.5 16.4 0.057 13.7 3.7 2.8 2 0 0 2 2 2 0 RING-like domain zf-RING_5 PF14634.6 GAM21897.1 - 3.1 7.8 15.1 0.76 9.8 4.6 3.5 3 0 0 3 3 3 0 zinc-RING finger domain Metallophos PF00149.28 GAM21898.1 - 1.6e-39 136.5 0.0 2.1e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 GAM21898.1 - 0.04 13.5 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain TM2 PF05154.16 GAM21899.1 - 7.6e-19 67.8 13.5 1e-18 67.4 13.5 1.1 1 0 0 1 1 1 1 TM2 domain TrkH PF02386.16 GAM21900.1 - 4.8e-67 226.5 24.2 1.6e-64 218.2 21.0 2.1 2 0 0 2 2 2 2 Cation transport protein ABC2_membrane_3 PF12698.7 GAM21901.1 - 3.1e-20 72.6 32.9 3.1e-20 72.6 32.9 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 GAM21901.1 - 1e-13 52.0 0.0 2.1e-11 44.5 0.0 3.1 2 1 1 3 3 3 1 ABC transporter AAA_21 PF13304.6 GAM21901.1 - 1.9e-08 34.5 0.0 1.1e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 GAM21901.1 - 0.12 11.6 12.0 0.31 10.3 12.0 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein Tim54 PF11711.8 GAM21901.1 - 0.13 11.0 1.0 0.21 10.3 1.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 STATa_Ig PF18214.1 GAM21902.1 - 4.5e-45 152.6 0.3 4.5e-45 152.6 0.3 2.6 2 1 0 2 2 2 1 STATa Immunoglobulin-like domain EF-hand_12 PF17901.1 GAM21902.1 - 2.2e-42 143.4 1.3 2.2e-42 143.4 1.3 2.4 2 0 0 2 2 2 1 EF-hand fold domain Dict-STAT-coil PF09267.10 GAM21902.1 - 1.9e-37 128.1 13.7 1.9e-37 128.1 13.7 2.4 3 0 0 3 3 3 1 Dictyostelium STAT, coiled coil SH2 PF00017.24 GAM21902.1 - 3.7e-08 33.3 0.0 1.4e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 SH2 domain CDK2AP PF09806.9 GAM21902.1 - 0.028 14.5 7.4 0.055 13.5 7.4 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Cnd3 PF12719.7 GAM21903.1 - 1.6e-11 43.9 0.9 1.6e-11 43.9 0.9 5.2 4 1 1 5 5 5 2 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 GAM21903.1 - 7.7e-08 32.5 7.9 1.3e-05 25.3 0.6 4.3 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 TFCD_C PF12612.8 GAM21903.1 - 0.0024 17.7 1.5 0.92 9.3 0.1 3.2 3 0 0 3 3 3 2 Tubulin folding cofactor D C terminal DUF3439 PF11921.8 GAM21903.1 - 0.037 14.0 0.8 0.13 12.2 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) HEAT_EZ PF13513.6 GAM21903.1 - 0.15 12.6 0.0 1.2e+02 3.3 0.0 4.8 5 1 1 6 6 6 0 HEAT-like repeat Kelch_6 PF13964.6 GAM21904.1 - 2.5e-05 24.4 0.9 0.051 13.9 0.0 3.9 3 1 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 GAM21904.1 - 0.0045 16.6 0.3 1.5 8.4 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 GAM21904.1 - 0.011 16.1 0.0 0.46 10.8 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM21904.1 - 0.048 13.7 1.7 13 5.8 0.1 3.3 3 1 0 3 3 3 0 Galactose oxidase, central domain RRN3 PF05327.11 GAM21905.1 - 0.0023 16.5 4.9 0.0028 16.3 4.9 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 MAP65_ASE1 PF03999.12 GAM21905.1 - 0.033 12.9 7.9 0.043 12.5 7.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4363 PF14276.6 GAM21905.1 - 0.084 13.0 2.0 0.43 10.7 0.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4363) Serine_rich PF08824.10 GAM21905.1 - 0.093 12.7 6.3 0.29 11.1 1.1 2.4 1 1 1 2 2 2 0 Serine rich protein interaction domain DMAP1_like PF17024.5 GAM21905.1 - 0.14 12.3 3.5 0.11 12.7 0.4 2.1 2 0 0 2 2 2 0 Putative DMAP1-like Transposase_22 PF02994.14 GAM21905.1 - 0.22 11.7 2.6 0.25 11.5 0.1 2.2 3 0 0 3 3 3 0 L1 transposable element RBD-like domain DUF4795 PF16043.5 GAM21905.1 - 0.35 10.4 6.6 0.36 10.4 2.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Ras PF00071.22 GAM21906.1 - 8.4e-55 184.8 0.1 9.7e-55 184.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM21906.1 - 3.8e-20 72.3 0.0 6.9e-20 71.5 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM21906.1 - 5.8e-09 35.6 0.0 6.6e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM21906.1 - 0.00015 21.8 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM21906.1 - 0.00017 21.2 0.1 0.0029 17.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM21906.1 - 0.00039 20.4 0.1 0.3 11.0 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAM21906.1 - 0.00049 19.7 0.0 0.0022 17.6 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B PglD_N PF17836.1 GAM21906.1 - 0.085 13.5 0.2 0.15 12.7 0.2 1.6 1 1 0 1 1 1 0 PglD N-terminal domain CbiA PF01656.23 GAM21906.1 - 0.12 12.4 0.1 0.32 11.1 0.1 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 GAM21906.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Cpn60_TCP1 PF00118.24 GAM21907.1 - 1.6e-92 310.7 3.8 8.7e-92 308.3 3.8 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Drf_FH3 PF06367.16 GAM21909.1 - 4.2e-33 114.6 4.0 4.2e-33 114.6 4.0 2.0 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 GAM21909.1 - 9.4e-22 77.5 0.2 9.4e-22 77.5 0.2 1.6 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain TolA_bind_tri PF16331.5 GAM21909.1 - 0.02 14.9 3.0 4.3 7.5 0.6 3.0 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF1664 PF07889.12 GAM21909.1 - 0.048 13.7 3.2 1.6 8.7 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CC2-LZ PF16516.5 GAM21909.1 - 1.5 9.2 8.5 1.8 8.9 2.2 2.6 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FH2 PF02181.23 GAM21910.1 - 2.4e-82 277.1 7.5 3.1e-82 276.7 7.5 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain IATP PF04568.12 GAM21910.1 - 0.027 14.9 0.8 0.11 13.0 0.8 2.0 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP SOG2 PF10428.9 GAM21910.1 - 3 7.0 13.8 5.4 6.1 13.8 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.17 GAM21910.1 - 3.1 7.8 17.8 6 6.9 17.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein UT PF03253.14 GAM21911.1 - 6.3e-48 163.4 30.1 7.5e-48 163.1 30.1 1.1 1 0 0 1 1 1 1 Urea transporter Exo_endo_phos PF03372.23 GAM21912.1 - 1.8e-12 47.3 0.0 2.8e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MaoC_dehydrat_N PF13452.6 GAM21912.1 - 0.0047 17.0 0.3 0.01 16.0 0.1 1.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Opy2 PF09463.10 GAM21913.1 - 0.081 13.2 40.2 0.81 10.0 7.3 4.9 1 1 3 4 4 4 0 Opy2 protein TILa PF12714.7 GAM21913.1 - 1.7 8.7 27.1 0.16 12.0 1.6 4.0 2 2 2 4 4 4 0 TILa domain Ammonium_transp PF00909.21 GAM21914.1 - 2.1e-37 128.8 22.9 9.5e-37 126.6 22.9 2.2 1 1 0 1 1 1 1 Ammonium Transporter Family DUF1003 PF06210.11 GAM21914.1 - 0.42 10.7 3.3 0.73 10.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) ATG27 PF09451.10 GAM21915.1 - 1e-23 84.6 0.9 2.3e-23 83.4 0.9 1.5 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 GAM21915.1 - 2.8e-13 49.5 0.1 3.3e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 GAM21915.1 - 6.4e-05 23.0 1.1 6.4e-05 23.0 1.1 1.7 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat RasGEF PF00617.19 GAM21916.1 - 5.3e-51 173.3 1.1 1.1e-50 172.3 1.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM21916.1 - 5.6e-16 58.7 0.6 3e-15 56.3 0.6 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif DEP PF00610.21 GAM21916.1 - 4.5e-14 52.3 0.1 2.1e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) WD40 PF00400.32 GAM21918.1 - 2.3e-08 34.5 26.8 0.062 14.2 0.1 7.2 7 0 0 7 7 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM21918.1 - 0.00016 21.9 2.4 0.32 11.3 0.0 4.2 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain C1_1 PF00130.22 GAM21918.1 - 0.0032 17.3 6.9 0.0076 16.1 6.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.11 GAM21918.1 - 0.0046 16.9 1.7 0.013 15.4 1.7 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain RNHCP PF12647.7 GAM21918.1 - 0.02 14.8 6.4 0.052 13.5 6.4 1.7 1 0 0 1 1 1 0 RNHCP domain C1_2 PF03107.16 GAM21918.1 - 0.066 13.5 4.0 0.16 12.3 4.0 1.6 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 GAM21918.1 - 0.089 12.7 5.8 0.21 11.5 5.8 1.6 1 0 0 1 1 1 0 PHD-finger PQQ_3 PF13570.6 GAM21918.1 - 0.11 13.0 0.0 0.64 10.6 0.0 2.3 2 0 0 2 2 1 0 PQQ-like domain Zf_RING PF16744.5 GAM21918.1 - 0.29 11.3 4.7 1.5 9.0 4.7 2.2 1 0 0 1 1 1 0 KIAA1045 RING finger DUF2652 PF10851.8 GAM21918.1 - 0.37 10.9 0.0 0.37 10.9 0.0 3.1 4 0 0 4 4 3 0 Protein of unknown function (DUF2652) Androgen_recep PF02166.16 GAM21918.1 - 3.1 6.5 31.9 0.34 9.7 9.3 2.3 2 0 0 2 2 2 0 Androgen receptor Prok-RING_1 PF14446.6 GAM21918.1 - 5.4 7.0 7.0 10 6.1 7.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 GAM21918.1 - 8.8 6.0 12.0 1.8 8.3 8.3 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type ABC2_membrane PF01061.24 GAM21919.1 - 1.1e-70 237.3 66.5 8.3e-37 126.6 23.8 3.0 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 GAM21919.1 - 1.3e-47 161.8 0.0 3.2e-24 86.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAM21919.1 - 4.4e-09 36.6 0.1 0.32 10.8 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAM21919.1 - 1.6e-07 31.4 0.1 0.0023 17.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAM21919.1 - 7e-07 29.8 0.0 0.063 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GAM21919.1 - 2.9e-06 26.9 1.4 0.0017 18.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 GAM21919.1 - 2e-05 24.6 0.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_22 PF13401.6 GAM21919.1 - 3.2e-05 24.2 0.2 0.23 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 GAM21919.1 - 0.0002 21.3 0.3 0.068 13.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 GAM21919.1 - 0.0002 21.8 0.1 0.066 13.6 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAM21919.1 - 0.00093 19.4 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAM21919.1 - 0.0011 18.6 0.1 0.66 9.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAM21919.1 - 0.0015 18.6 0.0 3.1 7.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase IstB_IS21 PF01695.17 GAM21919.1 - 0.0025 17.6 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 GAM21919.1 - 0.0027 18.2 2.7 0.82 10.1 0.1 2.7 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 GAM21919.1 - 0.0032 17.8 0.0 3.4 8.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase PDR_assoc PF08370.11 GAM21919.1 - 0.004 16.9 13.9 0.061 13.1 0.1 3.3 3 0 0 3 3 2 2 Plant PDR ABC transporter associated AAA_18 PF13238.6 GAM21919.1 - 0.0046 17.5 2.7 1.4 9.5 0.0 2.7 3 0 0 3 3 2 2 AAA domain PDR_CDR PF06422.12 GAM21919.1 - 0.0095 15.8 1.1 0.0095 15.8 1.1 3.7 4 0 0 4 4 2 2 CDR ABC transporter AAA_28 PF13521.6 GAM21919.1 - 0.011 16.0 0.1 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAM21919.1 - 0.011 15.7 0.0 0.67 9.8 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 GAM21919.1 - 0.012 14.3 0.0 0.081 11.6 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 GAM21919.1 - 0.015 15.0 0.5 5 6.8 0.3 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAM21919.1 - 0.023 14.0 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 GAM21919.1 - 0.076 12.6 1.2 8.2 6.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 GAM21919.1 - 0.083 12.6 0.4 9.2 5.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 GAM21919.1 - 0.14 11.9 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 GAM21919.1 - 0.21 12.0 0.7 11 6.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 GAM21919.1 - 0.22 10.6 0.3 9.3 5.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 GAM21919.1 - 0.25 11.1 0.9 11 5.8 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 GAM21919.1 - 0.27 11.5 1.0 3.6 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GAM21919.1 - 0.32 11.0 2.4 6.6 6.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAM21919.1 - 0.74 9.3 0.0 0.74 9.3 0.0 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region TCR PF03638.15 GAM21920.1 - 1.7e-22 79.5 56.6 6.4e-12 45.6 24.2 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 GAM21920.1 - 0.00019 21.5 41.5 0.00056 20.0 15.7 2.8 2 0 0 2 2 2 2 CXC domain of E3 ubiquitin-protein ligase MSL2 DUF4845 PF16137.5 GAM21920.1 - 0.2 12.5 0.1 0.2 12.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4845) CD34_antigen PF06365.12 GAM21921.1 - 0.018 14.6 0.2 0.036 13.6 0.2 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Orf78 PF06024.12 GAM21921.1 - 0.11 12.8 0.3 0.26 11.6 0.3 1.6 1 0 0 1 1 1 0 Orf78 (ac78) HEAT PF02985.22 GAM21922.1 - 9.9e-37 121.8 6.9 5e-05 23.2 0.0 9.6 10 1 1 11 11 10 7 HEAT repeat HEAT_2 PF13646.6 GAM21922.1 - 4.8e-20 71.7 0.0 0.0014 19.0 0.0 6.6 4 1 1 6 6 6 4 HEAT repeats Vac14_Fab1_bd PF12755.7 GAM21922.1 - 5.6e-13 49.3 1.9 0.012 16.2 0.0 6.2 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAM21922.1 - 4.5e-09 36.6 5.6 0.21 11.6 0.4 5.4 2 2 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAM21922.1 - 1.3e-08 35.1 0.1 5.1 7.7 0.0 5.8 6 1 0 6 6 5 3 HEAT-like repeat Arm PF00514.23 GAM21922.1 - 8e-05 22.5 0.9 13 5.9 0.1 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF4042 PF13251.6 GAM21922.1 - 0.0053 16.5 0.3 15 5.2 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) RasGEF_N_2 PF14663.6 GAM21922.1 - 0.027 14.9 0.4 12 6.4 0.0 3.8 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3730 PF12530.8 GAM21922.1 - 0.028 14.0 1.0 0.3 10.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) Wap1 PF16997.5 GAM21922.1 - 0.034 13.3 0.1 0.034 13.3 0.1 2.9 3 1 0 3 3 3 0 Wap1 domain Cohesin_HEAT PF12765.7 GAM21922.1 - 0.12 12.8 0.1 10 6.6 0.1 3.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion SPX PF03105.19 GAM21922.1 - 0.28 11.0 6.0 0.46 10.3 6.0 1.3 1 0 0 1 1 1 0 SPX domain Velvet PF11754.8 GAM21922.1 - 1.4 8.8 9.8 3.1 7.7 9.8 1.5 1 0 0 1 1 1 0 Velvet factor SR-25 PF10500.9 GAM21922.1 - 6.9 6.2 18.1 14 5.2 18.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SRF-TF PF00319.18 GAM21923.1 - 2.4e-21 75.0 0.1 3.6e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CCDC24 PF15669.5 GAM21923.1 - 0.06 13.2 5.2 0.16 11.8 2.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Herpes_pp85 PF04637.12 GAM21923.1 - 1.3 7.4 7.3 2.3 6.6 7.3 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DOT1 PF08123.13 GAM21924.1 - 0.0026 17.3 0.2 1.3 8.5 0.1 2.4 1 1 1 2 2 2 2 Histone methylation protein DOT1 Tom22 PF04281.13 GAM21924.1 - 0.063 13.1 4.9 0.084 12.7 4.1 1.6 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF3732 PF12532.8 GAM21924.1 - 0.28 10.7 5.1 0.41 10.2 4.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3732) MscS_TM PF12794.7 GAM21924.1 - 0.46 9.3 2.2 0.68 8.7 2.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Nup54 PF13874.6 GAM21925.1 - 3.1e-27 95.4 2.6 3.1e-27 95.4 2.6 3.1 4 0 0 4 4 4 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 GAM21925.1 - 0.00025 21.8 70.0 0.025 15.4 35.9 2.8 1 1 1 2 2 2 2 Nucleoporin FG repeat region Med15 PF09606.10 GAM21925.1 - 0.00034 19.5 25.6 0.0004 19.2 25.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.6 GAM21925.1 - 2.6 7.2 12.4 0.64 9.2 6.4 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Presenilin PF01080.17 GAM21925.1 - 7.6 5.2 7.8 12 4.6 7.8 1.3 1 0 0 1 1 1 0 Presenilin COX7C PF02935.16 GAM21927.1 - 0.0037 17.5 0.4 0.0054 17.0 0.4 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc TPR_12 PF13424.6 GAM21928.1 - 1.1e-06 28.8 0.2 0.56 10.5 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21928.1 - 3.5e-05 23.6 4.2 0.0032 17.5 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM21928.1 - 0.001 19.7 1.0 5.5 8.1 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM21928.1 - 0.0012 19.4 0.1 1.2 9.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM21928.1 - 0.0014 18.3 0.0 0.0014 18.3 0.0 3.6 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2400 PF09674.10 GAM21928.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) ANAPC3 PF12895.7 GAM21928.1 - 0.1 12.8 0.9 4.8 7.5 0.0 3.3 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Syntaxin-18_N PF10496.9 GAM21928.1 - 0.13 12.5 0.7 0.75 10.1 0.2 2.4 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus TPR_MalT PF17874.1 GAM21928.1 - 0.15 11.4 0.0 0.37 10.1 0.0 1.6 1 1 1 2 2 2 0 MalT-like TPR region tRNA-synt_2c PF01411.19 GAM21929.1 - 1.7e-164 548.4 0.0 2.3e-164 548.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAM21929.1 - 1.3e-17 63.6 0.8 2.8e-17 62.5 0.8 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF1664 PF07889.12 GAM21929.1 - 0.073 13.1 1.4 8.9 6.4 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nucleoporin_FG PF13634.6 GAM21930.1 - 1.5e-11 44.9 50.2 5.8e-07 30.3 23.2 8.5 5 2 3 8 8 8 4 Nucleoporin FG repeat region zf-RanBP PF00641.18 GAM21930.1 - 0.082 12.2 6.3 0.15 11.4 6.3 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF1857 PF08982.11 GAM21930.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) T2SSC PF11356.8 GAM21930.1 - 3.1 7.7 4.2 4.5 7.2 0.8 3.0 1 1 1 2 2 2 0 Type II secretion system protein C Band_7 PF01145.25 GAM21931.1 - 0.00014 21.9 9.9 0.0011 19.0 9.9 2.2 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 GAM21931.1 - 0.073 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Ank_2 PF12796.7 GAM21932.1 - 0.033 14.8 0.2 3.7 8.2 0.0 3.1 2 2 2 4 4 4 0 Ankyrin repeats (3 copies) Rtt106 PF08512.12 GAM21937.1 - 5.7e-25 87.6 0.1 1.9e-23 82.7 0.1 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like POB3_N PF17292.2 GAM21937.1 - 2.5e-24 85.5 0.5 2.1e-22 79.4 0.1 3.3 3 1 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 GAM21937.1 - 1.3e-20 73.1 0.5 1.4e-19 69.8 0.1 2.7 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) DUF4636 PF15468.6 GAM21937.1 - 0.013 15.2 1.9 0.022 14.5 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) UCH_N PF16674.5 GAM21937.1 - 0.04 13.9 1.6 3 7.8 0.0 3.5 4 0 0 4 4 4 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 Hexokinase_2 PF03727.16 GAM21937.1 - 0.095 12.1 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Hexokinase Med10 PF09748.9 GAM21938.1 - 9.3e-26 90.2 1.4 1.1e-25 90.0 0.8 1.3 1 1 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex SUKH_5 PF14567.6 GAM21938.1 - 0.015 15.0 0.5 2.7 7.7 0.1 2.4 1 1 0 2 2 2 0 SMI1-KNR4 cell-wall DUF3972 PF13118.6 GAM21938.1 - 0.027 14.9 0.5 0.027 14.9 0.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3972) AAA_22 PF13401.6 GAM21938.1 - 0.039 14.2 0.5 0.079 13.2 0.2 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran_Xtn PF12848.7 GAM21938.1 - 0.33 11.0 5.8 2.4 8.2 0.3 2.5 2 1 0 2 2 2 0 ABC transporter PAC2 PF09754.9 GAM21939.1 - 1.1e-22 81.1 0.0 1.4e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 PAC2 family NapE PF06796.11 GAM21940.1 - 0.37 10.4 4.9 1.2 8.7 4.9 1.9 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Phage_holin_5_2 PF16079.5 GAM21940.1 - 0.86 10.0 7.5 0.29 11.5 1.5 2.5 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Pterin_4a PF01329.19 GAM21941.1 - 7.3e-32 109.4 0.1 8.8e-32 109.1 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Yip1 PF04893.17 GAM21942.1 - 5.4e-14 52.3 19.2 8.1e-14 51.7 19.2 1.2 1 0 0 1 1 1 1 Yip1 domain Cpn60_TCP1 PF00118.24 GAM21943.1 - 2.2e-39 135.4 4.9 1.4e-38 132.8 4.9 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DnaB PF00772.21 GAM21943.1 - 0.089 12.9 1.4 4.7 7.4 0.1 3.1 3 0 0 3 3 3 0 DnaB-like helicase N terminal domain RT_RNaseH_2 PF17919.1 GAM21944.1 - 0.08 13.0 1.7 0.11 12.6 1.7 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase TFIIF_alpha PF05793.12 GAM21944.1 - 0.23 10.0 6.1 0.29 9.7 6.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1624 PF07786.12 GAM21945.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Glycoprotein PF03409.15 GAM21945.1 - 0.15 10.8 9.3 0.18 10.6 9.3 1.0 1 0 0 1 1 1 0 Transmembrane glycoprotein Mito_carr PF00153.27 GAM21946.1 - 1.1e-68 227.2 4.0 4.6e-24 84.2 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAM21946.1 - 0.0003 20.0 1.4 0.0074 15.5 0.0 2.6 2 1 1 3 3 3 2 Gammaproteobacterial serine protease FYVE PF01363.21 GAM21947.1 - 1.4e-16 60.3 15.0 1.4e-16 60.3 15.0 2.1 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 GAM21947.1 - 1.7e-11 44.5 9.3 2.2e-08 34.6 0.1 3.5 4 0 0 4 4 4 2 PH domain PH_3 PF14593.6 GAM21947.1 - 5.6e-07 29.6 3.1 0.019 15.1 0.0 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 GAM21947.1 - 6e-05 23.4 0.7 6e-05 23.4 0.7 3.1 2 1 1 3 3 3 1 Pleckstrin homology domain PH_2 PF08458.10 GAM21947.1 - 0.0013 19.0 1.6 0.0033 17.8 1.6 1.7 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PH_8 PF15409.6 GAM21947.1 - 0.061 13.6 3.3 0.16 12.3 0.0 3.0 2 1 1 3 3 3 0 Pleckstrin homology domain zf-RING_5 PF14634.6 GAM21947.1 - 0.53 10.3 17.8 1.2 9.1 17.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM21947.1 - 2.5 8.2 13.5 0.73 9.9 8.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAM21947.1 - 8.4 6.6 15.4 46 4.3 0.1 3.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING XRN_N PF03159.18 GAM21948.1 - 5.1e-77 258.6 0.0 5.1e-77 258.6 0.0 3.0 3 1 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 GAM21948.1 - 3.2e-73 247.2 13.8 2.4e-55 188.3 4.3 4.6 4 2 1 5 5 5 2 Xrn1 helical domain SH3_12 PF18129.1 GAM21948.1 - 4.6e-22 77.9 0.3 2.2e-19 69.3 0.4 2.4 2 0 0 2 2 2 2 Xrn1 SH3-like domain XRN1_D1 PF18332.1 GAM21948.1 - 1.2e-19 70.8 0.0 1.2e-19 70.8 0.0 2.9 2 1 1 3 3 3 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 GAM21948.1 - 0.00033 20.8 0.0 0.00033 20.8 0.0 3.2 5 0 0 5 5 5 1 Exoribonuclease Xrn1 D2/D3 domain zf-AN1 PF01428.16 GAM21949.1 - 1.5e-09 37.8 10.1 2.9e-09 36.9 10.1 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger UBX PF00789.20 GAM21949.1 - 1.3e-06 28.5 0.0 2.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain Pur_ac_phosph_N PF16656.5 GAM21950.1 - 8.8e-18 64.7 7.8 8.8e-18 64.7 7.8 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 GAM21950.1 - 8.3e-16 58.6 0.5 2.9e-15 56.9 0.1 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 GAM21950.1 - 9.7e-16 58.9 0.1 1.7e-15 58.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM21950.1 - 0.0063 16.7 0.0 0.028 14.6 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.32 GAM21951.1 - 2.4e-26 91.4 18.0 4.6e-06 27.3 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM21951.1 - 7.9e-19 67.8 0.1 0.0019 18.5 0.0 5.4 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM21951.1 - 1.2e-05 24.5 0.2 0.19 10.6 0.0 2.9 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 GAM21951.1 - 0.003 16.0 0.0 0.98 7.6 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz TLP-20 PF06088.11 GAM21951.1 - 0.0054 16.6 0.5 0.0054 16.6 0.5 2.3 3 0 0 3 3 3 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PD40 PF07676.12 GAM21951.1 - 0.0084 16.0 2.7 0.21 11.6 0.2 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF3439 PF11921.8 GAM21951.1 - 0.22 11.5 11.1 0.51 10.3 11.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Proteasome_A_N PF10584.9 GAM21951.1 - 3.6 7.4 9.9 1.6e+02 2.1 0.0 5.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Roughex PF06020.11 GAM21951.1 - 5.4 6.0 12.5 8.4 5.4 12.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DNA_pol_E_B PF04042.16 GAM21952.1 - 2.5e-28 98.9 1.7 2.5e-28 98.9 1.7 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 GAM21952.1 - 0.0024 17.9 4.8 0.004 17.2 4.8 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Parathyroid PF01279.17 GAM21952.1 - 4.4 8.0 8.2 0.99 10.0 4.5 1.7 2 0 0 2 2 2 0 Parathyroid hormone family ketoacyl-synt PF00109.26 GAM21953.1 - 3.4e-51 174.3 0.7 4.4e-51 173.9 0.2 1.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM21953.1 - 2.5e-33 114.6 1.5 5.1e-33 113.6 1.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GAM21953.1 - 0.00076 18.9 0.3 0.0018 17.7 0.3 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain FA_hydroxylase PF04116.13 GAM21954.1 - 8.5e-28 97.3 15.6 8.5e-28 97.3 15.6 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DIOX_N PF14226.6 GAM21955.1 - 1.8e-28 99.7 0.0 3.2e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM21955.1 - 2.6e-22 79.2 0.1 4.2e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DENN PF02141.21 GAM21957.1 - 3.6e-30 105.3 1.3 1.1e-29 103.8 1.3 1.9 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAM21957.1 - 6e-07 30.1 0.5 6e-07 30.1 0.5 2.7 2 1 0 2 2 2 1 uDENN domain RGS PF00615.19 GAM21958.1 - 2e-24 86.1 1.6 2.5e-24 85.8 1.6 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain FAM92 PF06730.11 GAM21959.1 - 0.039 13.4 0.3 0.054 12.9 0.3 1.2 1 0 0 1 1 1 0 FAM92 protein TIG PF01833.24 GAM21960.1 - 0.003 17.6 7.8 0.05 13.7 0.2 3.0 3 0 0 3 3 3 2 IPT/TIG domain PufQ PF05398.11 GAM21960.1 - 0.036 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 PufQ cytochrome subunit Shisa PF13908.6 GAM21960.1 - 0.045 14.0 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MtrD PF04207.12 GAM21960.1 - 0.14 11.9 2.1 1.6 8.4 0.3 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D DUF5102 PF17104.5 GAM21961.1 - 0.00015 21.9 1.0 0.00015 21.9 1.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF5102) SNARE PF05739.19 GAM21962.1 - 4.6e-10 39.3 0.7 6.8e-10 38.8 0.7 1.3 1 0 0 1 1 1 1 SNARE domain DUF5345 PF17280.2 GAM21962.1 - 0.52 10.3 3.2 0.84 9.7 3.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5345) DUF4419 PF14388.6 GAM21964.1 - 8.1e-94 314.4 0.8 9.6e-94 314.2 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Ank_2 PF12796.7 GAM21966.1 - 4.6e-31 107.2 8.9 2.7e-08 34.3 0.2 6.7 6 1 1 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM21966.1 - 8.1e-23 80.2 10.2 3.6e-08 33.5 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM21966.1 - 9.1e-20 70.8 13.0 2.1e-05 25.0 0.1 8.1 7 2 1 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM21966.1 - 3.9e-17 60.6 11.4 0.011 16.2 0.2 9.3 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 GAM21966.1 - 1.2e-15 57.1 17.3 0.00027 21.2 0.5 7.5 8 0 0 8 8 8 4 Ankyrin repeat FNIP PF05725.12 GAM21967.1 - 5e-75 247.4 23.4 2.1e-14 53.4 0.0 9.9 6 4 2 9 9 9 8 FNIP Repeat DUF1769 PF08588.10 GAM21967.1 - 0.074 13.3 0.1 20 5.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1769) FNIP PF05725.12 GAM21968.1 - 9.8e-29 99.3 28.8 1.8e-05 24.8 0.0 9.3 7 3 2 9 9 9 8 FNIP Repeat LRR_4 PF12799.7 GAM21968.1 - 2.1 8.9 22.6 3.6 8.1 1.6 7.8 8 1 2 10 10 10 0 Leucine Rich repeats (2 copies) DUF4419 PF14388.6 GAM21970.1 - 8.6e-101 337.3 2.6 1e-100 337.1 2.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) TPR_1 PF00515.28 GAM21971.1 - 1.6e-12 46.7 2.8 6.8e-05 22.5 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21971.1 - 1.5e-10 40.3 3.7 0.0091 16.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM21971.1 - 1.2e-09 37.7 0.1 0.0009 18.9 0.0 2.9 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 GAM21971.1 - 5.3e-05 23.1 5.3 0.0007 19.6 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM21971.1 - 0.00049 20.3 2.5 0.88 9.9 2.9 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM21971.1 - 0.0018 19.0 0.1 0.028 15.2 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM21971.1 - 0.021 15.2 1.8 11 6.6 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM21971.1 - 0.025 15.1 0.4 0.073 13.6 0.4 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat Acyl-CoA_dh_C PF12806.7 GAM21971.1 - 0.12 12.5 0.5 0.24 11.6 0.5 1.4 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like TPR_6 PF13174.6 GAM21971.1 - 6.5 7.6 6.2 2.9 8.7 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Abi_2 PF07751.11 GAM21972.1 - 0.14 12.4 6.5 0.22 11.7 6.5 1.3 1 1 0 1 1 1 0 Abi-like protein Vfa1 PF08432.10 GAM21972.1 - 0.29 11.5 13.3 0.34 11.2 13.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 GAM21972.1 - 1.1 8.4 1.9 1 8.5 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1690 PF07956.11 GAM21972.1 - 4 7.8 15.0 1.8 9.0 11.8 1.9 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Rep_fac-A_C PF08646.10 GAM21973.1 - 0.00011 22.0 0.5 0.00018 21.3 0.5 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain Defensin_5 PF18251.1 GAM21973.1 - 0.12 12.5 1.4 0.4 10.8 1.4 1.9 1 0 0 1 1 1 0 Fungal defensin Copsin DUF2838 PF10998.8 GAM21974.1 - 2e-36 124.6 11.8 2e-36 124.6 11.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF2207 PF09972.9 GAM21974.1 - 0.091 11.5 1.9 0.1 11.3 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Sigma70_ner PF04546.13 GAM21974.1 - 1.1 9.1 7.8 2 8.2 7.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Enkurin PF13864.6 GAM21974.1 - 1.8 9.0 9.3 5 7.6 9.2 1.9 1 1 0 1 1 1 0 Calmodulin-binding NOA36 PF06524.12 GAM21974.1 - 5.3 6.3 10.2 13 5.0 10.2 1.7 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.32 GAM21975.1 - 2.9e-34 116.5 15.2 2.8e-07 31.1 0.4 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM21975.1 - 2.4e-18 66.2 3.2 2.8e-05 24.3 0.0 5.8 4 1 1 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM21975.1 - 9.4e-08 32.2 0.9 0.00048 20.1 0.1 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A SGL PF08450.12 GAM21975.1 - 0.005 16.4 0.2 0.89 9.1 0.0 3.0 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Nbas_N PF15492.6 GAM21975.1 - 0.038 13.3 0.1 1.1 8.5 0.0 2.7 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 GAM21975.1 - 0.053 12.0 0.0 2 6.9 0.0 2.8 2 2 0 2 2 2 0 Cytochrome D1 heme domain SRA PF18491.1 GAM21975.1 - 0.26 11.4 0.1 0.26 11.4 0.1 3.9 4 0 0 4 4 4 0 SET and RING associated domain TFIIA PF03153.13 GAM21975.1 - 0.27 11.2 25.3 0.54 10.2 25.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acetyltransf_4 PF13420.7 GAM21977.1 - 4.1e-20 72.5 0.0 4.9e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM21977.1 - 7.8e-13 48.7 0.0 1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 GAM21977.1 - 8.6e-08 32.9 0.0 1e-07 32.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM21977.1 - 5.7e-07 29.9 0.1 9.5e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM21977.1 - 3.5e-05 23.7 0.0 7.7e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAM21977.1 - 0.00098 19.1 0.0 0.0017 18.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 GAM21977.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.4 1 1 0 1 1 1 0 GNAT acetyltransferase Hist_deacetyl PF00850.19 GAM21978.1 - 2e-82 277.1 0.7 1.1e-81 274.7 0.1 1.9 2 0 0 2 2 2 1 Histone deacetylase domain ComK PF06338.11 GAM21979.1 - 0.44 10.2 4.0 0.38 10.4 0.3 2.4 2 1 1 3 3 3 0 ComK protein NIF PF03031.18 GAM21980.1 - 2.6e-26 92.3 4.9 8e-26 90.7 0.9 2.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 GAM21980.1 - 5.1e-10 39.6 0.9 1.2e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAM21980.1 - 5.8e-08 32.6 0.0 1.3e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 GAM21980.1 - 0.00059 20.1 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 GAM21980.1 - 0.072 13.5 0.3 0.31 11.5 0.0 2.3 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Biotin_lipoyl_2 PF13533.6 GAM21980.1 - 0.13 12.1 0.0 25 4.8 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like HisK_sensor PF18698.1 GAM21980.1 - 0.51 10.7 9.6 7.5 6.9 2.4 4.2 4 0 0 4 4 4 0 Histidine kinase sensor domain Tubulin PF00091.25 GAM21981.1 - 6.8e-65 219.0 0.0 1.1e-64 218.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAM21981.1 - 1.9e-48 163.8 1.1 3e-48 163.1 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAM21981.1 - 5.1e-07 30.0 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 GAM21981.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Swm2 PF17083.5 GAM21981.1 - 0.057 13.4 0.3 0.25 11.4 0.1 2.0 2 0 0 2 2 2 0 Nucleolar protein Swm2 DNA_primase_lrg PF04104.14 GAM21982.1 - 2e-62 211.0 0.1 3.1e-62 210.4 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Isochorismatase PF00857.20 GAM21983.1 - 7.4e-33 114.2 0.0 9.1e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AAA_25 PF13481.6 GAM21983.1 - 0.074 12.6 0.0 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 GAM21984.1 - 7.4e-21 74.5 4.4 7.5e-11 42.5 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM21984.1 - 9.5e-15 54.8 1.3 2.2e-07 31.3 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM21984.1 - 1e-10 41.6 0.1 7.5e-06 26.1 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAM21984.1 - 5.6e-07 29.7 0.6 0.0029 18.0 0.5 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 GAM21984.1 - 1e-06 28.6 0.1 0.16 12.6 0.0 3.3 4 1 0 4 4 4 2 Ankyrin repeat PAP_central PF04928.17 GAM21985.1 - 1.3e-104 348.6 0.0 2.4e-104 347.7 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAM21985.1 - 8.7e-36 123.1 0.0 1.1e-34 119.6 0.0 2.4 2 1 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAM21985.1 - 4e-12 46.3 0.0 9.3e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAM21985.1 - 0.025 14.6 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 GAM21985.1 - 0.034 13.9 0.0 0.091 12.5 0.0 1.8 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain EZH2_N PF18601.1 GAM21986.1 - 0.018 15.4 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 EZH2 N-terminal domain Homeobox_KN PF05920.11 GAM21987.1 - 1.5e-16 60.0 0.6 3.2e-16 58.9 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAM21987.1 - 1.2e-06 28.2 0.1 2.4e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Homeodomain DUF3605 PF12239.8 GAM21988.1 - 5e-23 82.1 2.8 7.1e-22 78.4 2.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) Abi_HHR PF07815.14 GAM21988.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Abl-interactor HHR FNIP PF05725.12 GAM21989.1 - 4.8e-37 125.9 7.8 5.4e-09 36.1 0.1 9.1 5 2 4 9 9 9 7 FNIP Repeat LCM PF04072.14 GAM21990.1 - 5.6e-24 85.1 0.0 2.1e-23 83.3 0.0 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase E1_DerP2_DerF2 PF02221.15 GAM21991.1 - 7.8e-23 81.4 0.5 1.3e-22 80.7 0.5 1.4 1 0 0 1 1 1 1 ML domain Nse4_C PF08743.10 GAM21991.1 - 3.8e-22 78.4 0.6 1.6e-21 76.3 0.1 2.3 1 1 1 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 GAM21991.1 - 2e-08 34.2 0.6 4.6e-08 33.1 0.6 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4539 PF15072.6 GAM21992.1 - 1.7e-25 88.9 0.0 4.2e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) AIG1 PF04548.16 GAM21993.1 - 5.1e-10 39.0 1.7 4e-09 36.1 1.7 2.4 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GAM21993.1 - 2.6e-09 37.2 2.8 4.3e-09 36.5 0.8 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase zf-trcl PF13451.6 GAM21993.1 - 6.9e-08 32.3 13.9 3.7e-05 23.5 0.4 3.7 3 0 0 3 3 3 2 Probable zinc-ribbon domain Roc PF08477.13 GAM21993.1 - 1.2e-05 25.5 0.4 3.4e-05 24.0 0.0 2.0 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 GAM21993.1 - 4.6e-05 23.6 8.2 0.056 13.5 0.1 4.0 4 0 0 4 4 4 2 Dynamin family FtsK_SpoIIIE PF01580.18 GAM21993.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 GAM21993.1 - 0.0014 19.1 0.0 0.0076 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM21993.1 - 0.0015 18.4 0.1 0.0058 16.5 0.1 2.0 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 GAM21993.1 - 0.0016 19.0 15.5 0.77 10.2 15.5 3.1 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 GAM21993.1 - 0.0019 17.6 1.2 0.0028 17.0 0.1 1.8 2 0 0 2 2 2 1 Septin ABC_tran PF00005.27 GAM21993.1 - 0.0028 18.2 0.4 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 GAM21993.1 - 0.0043 17.3 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAM21993.1 - 0.0049 16.6 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 GAM21993.1 - 0.0064 16.0 0.1 0.023 14.2 0.1 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region Ras PF00071.22 GAM21993.1 - 0.012 15.3 0.1 0.033 13.8 0.1 1.9 1 0 0 1 1 1 0 Ras family ATP_bind_1 PF03029.17 GAM21993.1 - 0.014 15.2 4.1 0.23 11.2 0.1 3.0 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 GAM21993.1 - 0.014 15.7 0.5 0.091 13.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATPase PF06745.13 GAM21993.1 - 0.017 14.5 0.6 4.2 6.6 0.0 2.5 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 GAM21993.1 - 0.017 14.2 0.2 0.043 12.9 0.2 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein FeoB_N PF02421.18 GAM21993.1 - 0.018 14.6 4.1 2.9 7.4 0.1 3.2 2 1 0 3 3 3 0 Ferrous iron transport protein B DUF87 PF01935.17 GAM21993.1 - 0.039 14.0 2.8 0.047 13.8 0.1 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain Ploopntkinase3 PF18751.1 GAM21993.1 - 0.073 13.0 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 CLP1_P PF16575.5 GAM21993.1 - 0.078 12.8 2.5 0.26 11.1 0.0 3.0 3 1 1 4 4 4 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Cep57_MT_bd PF06657.13 GAM21993.1 - 3.7 8.1 11.8 3.7 8.1 0.5 4.1 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Cnn_1N PF07989.11 GAM21993.1 - 4.3 7.6 6.5 5.6 7.2 0.3 3.7 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 TPR_1 PF00515.28 GAM21994.1 - 1.3e-27 94.4 31.2 2.2e-05 24.1 0.0 13.1 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAM21994.1 - 2.2e-27 92.9 28.6 6e-05 22.9 0.0 12.6 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_14 PF13428.6 GAM21994.1 - 1.4e-17 62.8 7.3 0.01 16.6 0.1 9.9 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM21994.1 - 3.2e-17 61.2 28.3 7e-05 22.7 0.0 12.2 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM21994.1 - 1.7e-16 59.6 25.7 0.0052 16.4 0.0 11.0 10 3 4 14 14 13 4 TPR repeat TPR_19 PF14559.6 GAM21994.1 - 3.1e-16 59.6 21.0 0.0012 19.4 1.0 7.9 5 2 1 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 GAM21994.1 - 1.5e-12 47.5 7.0 0.12 12.5 0.1 6.8 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAM21994.1 - 1.1e-11 45.1 7.3 0.16 12.7 0.2 6.9 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM21994.1 - 1.6e-09 37.4 23.5 0.078 13.4 0.0 9.8 11 1 1 12 12 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM21994.1 - 6.2e-08 32.8 21.8 0.015 15.5 0.8 6.5 6 2 0 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAM21994.1 - 7.5e-07 28.7 5.9 3.8 7.8 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM21994.1 - 8.4e-07 29.2 28.1 0.16 12.3 0.0 10.6 6 4 5 11 11 11 1 Tetratricopeptide repeat TPR_20 PF14561.6 GAM21994.1 - 0.0019 18.5 6.9 2.9 8.3 0.2 6.2 4 3 4 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM21994.1 - 0.0094 15.4 2.7 0.053 12.9 0.2 3.3 2 1 1 3 3 3 1 MalT-like TPR region TPR_6 PF13174.6 GAM21994.1 - 0.013 16.1 14.9 14 6.6 0.0 8.0 8 0 0 8 8 6 0 Tetratricopeptide repeat Phage_prot_Gp6 PF05133.14 GAM21994.1 - 0.02 14.0 2.0 0.036 13.2 2.0 1.4 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like TPR_15 PF13429.6 GAM21994.1 - 0.022 14.0 14.3 1.3 8.2 0.1 5.3 5 2 0 6 6 6 0 Tetratricopeptide repeat PIP5K PF01504.18 GAM21994.1 - 0.12 11.5 3.2 8.7 5.5 0.1 3.0 2 1 1 3 3 3 0 Phosphatidylinositol-4-phosphate 5-Kinase MAS20 PF02064.15 GAM21994.1 - 0.15 12.2 0.5 17 5.5 0.0 3.6 3 0 0 3 3 3 0 MAS20 protein import receptor ChAPs PF09295.10 GAM21994.1 - 0.25 10.3 6.7 0.3 10.1 0.4 2.9 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 GAM21994.1 - 1.1 9.3 8.4 38 4.3 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat GPCR_chapero_1 PF11904.8 GAM21995.1 - 4.5e-24 85.4 0.4 7.4e-24 84.7 0.4 1.3 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 GAM21995.1 - 4.2e-07 30.5 0.0 2.6e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM21995.1 - 7.8e-06 26.1 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM21995.1 - 1e-05 26.0 0.1 4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM21995.1 - 3.4e-05 24.1 0.1 8.3e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 GAM21995.1 - 0.00016 21.9 0.0 0.00082 19.7 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat LRR_6 PF13516.6 GAM21996.1 - 6.4e-13 47.6 12.8 0.065 13.3 0.0 8.2 9 0 0 9 9 9 5 Leucine Rich repeat SAPS PF04499.15 GAM21996.1 - 0.0001 21.3 0.4 0.0001 21.3 0.4 4.2 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein tRNA-synt_1c PF00749.21 GAM21997.1 - 2.2e-113 378.3 0.1 4.1e-113 377.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAM21997.1 - 1.3e-50 171.7 0.3 3.7e-50 170.2 0.1 1.9 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 GAM21997.1 - 5.1e-45 153.4 0.4 9e-45 152.6 0.4 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 GAM21997.1 - 1.1e-11 45.4 0.7 3e-11 44.1 0.7 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 GBV-C_env PF12786.7 GAM21997.1 - 0.026 13.2 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope tRNA-synt_1e PF01406.19 GAM21997.1 - 0.047 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Trypan_PARP PF05887.11 GAM21998.1 - 0.0011 18.9 21.2 0.0011 18.9 21.2 4.6 3 1 2 5 5 5 1 Procyclic acidic repetitive protein (PARP) DUF393 PF04134.12 GAM21999.1 - 1.2e-26 94.3 0.1 1.5e-26 93.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Pkinase_Tyr PF07714.17 GAM22000.1 - 6.4e-49 166.6 0.0 9.7e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM22000.1 - 5.4e-46 157.1 0.0 1.2e-45 156.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 GAM22000.1 - 6.8e-28 97.1 5.3 1.8e-11 44.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM22000.1 - 4e-22 78.3 3.8 3.7e-06 27.4 0.3 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM22000.1 - 5.8e-18 64.5 1.2 0.00084 19.7 0.3 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 GAM22000.1 - 4.9e-17 60.3 2.0 0.0029 18.0 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAM22000.1 - 1.6e-16 60.2 14.4 7.4e-06 26.1 0.8 4.8 4 1 1 5 5 4 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 GAM22000.1 - 2.5e-14 53.5 0.5 1.2e-13 51.3 0.3 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM22000.1 - 5.5e-10 39.2 0.3 1.3e-09 38.0 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) APH PF01636.23 GAM22000.1 - 0.04 13.8 0.1 0.21 11.5 0.1 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAM22000.1 - 0.094 12.3 0.2 0.52 9.9 0.0 2.0 1 1 1 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.17 GAM22002.1 - 2.9e-60 203.7 0.0 4.2e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM22002.1 - 1.7e-44 152.2 0.0 3.1e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 GAM22002.1 - 7.7e-37 124.9 40.8 2.1e-10 40.2 7.2 6.5 2 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAM22002.1 - 5.1e-27 93.5 49.2 3.5e-06 27.2 1.0 7.6 3 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAM22002.1 - 6e-11 42.2 15.6 0.00012 21.7 2.9 3.8 1 1 0 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 GAM22002.1 - 0.0014 18.9 47.4 5.1 8.0 2.4 12.1 11 1 0 11 11 11 3 Leucine Rich Repeat APH PF01636.23 GAM22002.1 - 0.033 14.1 0.7 25 4.7 0.0 3.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family EPL1 PF10513.9 GAM22002.1 - 2.4 8.5 9.5 2 8.8 4.2 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like MMM1 PF10296.9 GAM22003.1 - 9.4e-11 41.3 4.3 4.6e-07 29.2 0.5 3.2 2 1 1 3 3 3 2 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 GAM22003.1 - 1.1e-05 25.9 1.1 6.9e-05 23.3 0.7 2.5 1 1 1 2 2 2 1 PH domain PH_10 PF15411.6 GAM22003.1 - 0.35 11.1 2.5 1.9 8.7 0.6 2.7 1 1 1 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 GAM22003.1 - 0.44 11.0 1.9 3.3 8.2 0.6 2.7 1 1 1 2 2 2 0 Pleckstrin homology domain Cation_ATPase_C PF00689.21 GAM22004.1 - 4e-30 104.9 13.1 4e-30 104.9 13.1 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAM22004.1 - 9.2e-15 54.6 1.0 4.4e-14 52.4 1.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAM22004.1 - 1.3e-06 28.9 0.0 2.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM22004.1 - 7.3e-05 22.8 0.0 0.001 19.1 0.0 2.5 1 1 0 1 1 1 1 Cation transport ATPase (P-type) DUF1600 PF07667.11 GAM22004.1 - 0.02 15.1 1.2 0.02 15.1 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1600) Phos_pyr_kin PF08543.12 GAM22005.1 - 1.6e-16 60.4 0.0 2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 GAM22005.1 - 2.8e-11 43.3 0.4 8.7e-11 41.7 0.3 2.0 2 1 0 2 2 2 1 pfkB family carbohydrate kinase DUF3029 PF11230.8 GAM22005.1 - 0.0038 15.7 0.0 0.0056 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3029) PIP5K PF01504.18 GAM22006.1 - 2.4e-92 309.1 0.0 4.9e-92 308.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase RhoGAP PF00620.27 GAM22007.1 - 9.7e-22 77.4 0.3 3.1e-21 75.8 0.3 1.9 1 0 0 1 1 1 1 RhoGAP domain RCC1 PF00415.18 GAM22009.1 - 3.9e-31 107.4 8.6 1.3e-07 32.1 0.1 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM22009.1 - 2.1e-20 72.0 19.8 3.9e-05 23.3 0.1 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Aminotran_1_2 PF00155.21 GAM22010.1 - 3.5e-46 158.0 0.0 4e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II STAG PF08514.11 GAM22012.1 - 1.2e-14 54.1 0.3 1.2e-14 54.1 0.3 3.8 4 0 0 4 4 4 1 STAG domain Nop14 PF04147.12 GAM22012.1 - 4.4 5.4 32.5 0.086 11.1 10.1 2.8 2 0 0 2 2 2 0 Nop14-like family Peptidase_M50B PF13398.6 GAM22013.1 - 0.36 10.4 16.7 0.061 13.0 12.8 1.6 1 1 1 2 2 2 0 Peptidase M50B-like DUF3792 PF12670.7 GAM22013.1 - 0.59 10.3 24.6 0.84 9.8 24.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) CbiQ PF02361.16 GAM22013.1 - 0.8 9.3 11.9 0.94 9.1 11.9 1.1 1 0 0 1 1 1 0 Cobalt transport protein DUF4229 PF14012.6 GAM22013.1 - 2.2 8.4 13.3 35 4.6 10.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4229) DUF4014 PF13198.6 GAM22013.1 - 5 7.6 7.5 9.6 6.7 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) RCC1 PF00415.18 GAM22014.1 - 1.4e-61 204.9 23.7 9.8e-14 51.7 0.7 8.4 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM22014.1 - 5.5e-47 156.7 30.3 3.4e-08 33.1 1.1 7.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 GAM22014.1 - 0.15 12.1 2.0 51 4.1 0.0 4.1 4 0 0 4 4 4 0 Kelch motif CPSF_A PF03178.15 GAM22014.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 CPSF A subunit region FNIP PF05725.12 GAM22016.1 - 1.5e-52 175.5 8.1 2.2e-10 40.5 0.1 7.3 6 1 2 8 8 8 7 FNIP Repeat TIG PF01833.24 GAM22017.1 - 3.8e-08 33.3 15.9 0.0015 18.6 0.9 5.6 4 1 0 4 4 4 3 IPT/TIG domain Lectin_C PF00059.21 GAM22017.1 - 0.039 14.7 0.0 0.093 13.5 0.0 1.6 1 0 0 1 1 1 0 Lectin C-type domain EGF_2 PF07974.13 GAM22017.1 - 0.76 10.2 13.5 1.5 9.3 13.5 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 GAM22017.1 - 3 8.0 6.6 6.5 6.9 6.6 1.6 1 0 0 1 1 1 0 Tenascin EGF domain MutS_V PF00488.21 GAM22018.1 - 1e-83 280.0 0.3 1.9e-83 279.1 0.3 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAM22018.1 - 1e-30 107.4 4.4 6.1e-30 104.9 1.6 2.5 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 GAM22018.1 - 2.6e-13 50.1 1.2 2.6e-13 50.1 1.2 2.7 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.17 GAM22018.1 - 3.1e-11 43.7 1.1 1.5e-10 41.4 0.0 2.6 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 GAM22018.1 - 6.9e-09 35.9 0.1 0.0036 17.5 0.1 2.8 2 0 0 2 2 2 2 MutS domain I AAA_27 PF13514.6 GAM22018.1 - 0.016 14.8 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAM22018.1 - 0.65 10.5 8.6 2.4 8.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF5408 PF17402.2 GAM22018.1 - 0.73 9.8 3.0 8.1 6.4 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5408) Baculo_PEP_C PF04513.12 GAM22018.1 - 8.7 6.4 11.8 10 6.1 0.2 4.0 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SnoaL PF07366.12 GAM22019.1 - 0.003 17.4 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 GAM22019.1 - 0.0067 17.1 0.0 0.0097 16.5 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SAM_decarbox PF01536.16 GAM22020.1 - 1.3e-104 350.0 0.0 1.5e-104 349.8 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase 7tm_3 PF00003.22 GAM22021.1 - 1.7e-26 93.4 12.0 2.9e-26 92.6 12.0 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 GAM22021.1 - 4e-13 49.0 4.1 5.6e-13 48.5 4.1 1.2 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like CclA_1 PF16942.5 GAM22021.1 - 0.082 13.2 3.0 0.17 12.1 0.1 2.6 2 0 0 2 2 2 0 Putative cyclic bacteriocin DUF4271 PF14093.6 GAM22021.1 - 7.3 6.4 27.3 0.29 11.0 7.6 3.9 2 1 3 5 5 5 0 Domain of unknown function (DUF4271) WD40 PF00400.32 GAM22022.1 - 3.8e-37 125.6 10.2 2e-06 28.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM22022.1 - 5.1e-16 58.7 0.1 0.0008 19.7 0.0 5.2 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM22022.1 - 0.086 12.2 0.0 0.97 8.7 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain Sld5 PF05916.11 GAM22023.1 - 2.9e-06 27.7 0.0 5.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein ApbA_C PF08546.11 GAM22023.1 - 0.074 13.3 0.0 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal ECH_1 PF00378.20 GAM22025.1 - 2.2e-55 187.7 0.0 2.6e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM22025.1 - 1.5e-30 106.9 0.0 1.1e-28 100.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 GAM22025.1 - 0.082 12.9 0.1 20 5.1 0.1 2.4 2 0 0 2 2 2 0 Peptidase family S49 Mpv17_PMP22 PF04117.12 GAM22026.1 - 1.2e-22 79.9 1.3 2.1e-22 79.1 1.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family BAR_3 PF16746.5 GAM22027.1 - 6.2e-66 222.5 16.3 1.1e-65 221.7 16.3 1.4 1 0 0 1 1 1 1 BAR domain of APPL family ArfGap PF01412.18 GAM22027.1 - 6.4e-38 129.4 0.2 6.4e-38 129.4 0.2 2.6 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 GAM22027.1 - 9.1e-17 61.4 17.1 1.1e-09 38.7 2.5 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) PH PF00169.29 GAM22027.1 - 1.7e-14 54.2 0.4 5.2e-14 52.6 0.4 1.8 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.6 GAM22027.1 - 2.4e-12 46.8 4.3 5.2e-09 36.2 0.4 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM22027.1 - 1.4e-08 35.1 0.5 2e-05 25.0 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) BAR PF03114.18 GAM22027.1 - 2.9e-07 30.4 8.2 8.1e-07 28.9 8.1 1.6 1 1 0 1 1 1 1 BAR domain Ank_3 PF13606.6 GAM22027.1 - 4.9e-06 26.5 1.4 0.28 11.9 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAM22027.1 - 4.2e-05 23.8 5.3 0.038 14.5 0.8 4.2 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.6 GAM22027.1 - 8.7e-05 22.7 0.0 0.00024 21.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Syntaxin_2 PF14523.6 GAM22027.1 - 0.001 19.4 0.3 0.001 19.4 0.3 2.9 3 1 1 4 4 3 1 Syntaxin-like protein BAR_3_WASP_bdg PF10456.9 GAM22027.1 - 0.0015 18.0 6.0 0.0068 15.9 6.0 1.9 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein PH_11 PF15413.6 GAM22027.1 - 0.014 15.8 0.8 0.014 15.8 0.8 3.4 2 1 0 2 2 2 0 Pleckstrin homology domain FlaC_arch PF05377.11 GAM22027.1 - 0.98 9.9 4.3 2.2 8.8 0.5 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Lactonase PF10282.9 GAM22028.1 - 0.032 13.5 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Kelch_6 PF13964.6 GAM22028.1 - 0.093 13.1 0.4 26 5.3 0.0 3.0 2 1 1 3 3 3 0 Kelch motif ANAPC15 PF15243.6 GAM22028.1 - 5.4 7.5 16.5 0.19 12.2 7.6 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 15 Kelch_6 PF13964.6 GAM22029.1 - 1e-08 35.1 3.4 0.012 15.8 0.2 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 GAM22029.1 - 0.083 12.9 0.8 2 8.5 0.1 3.6 4 0 0 4 4 4 0 Kelch motif ABC_tran_CTD PF16326.5 GAM22029.1 - 0.12 12.6 1.6 0.36 11.1 1.0 2.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain Kelch_4 PF13418.6 GAM22029.1 - 1.5 8.9 4.4 35 4.5 0.0 4.4 4 1 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM22030.1 - 3.9e-06 27.0 2.6 0.089 13.1 0.1 4.7 3 1 1 4 4 4 1 Kelch motif Kelch_4 PF13418.6 GAM22030.1 - 7e-05 22.7 2.5 0.51 10.4 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain YkyA PF10368.9 GAM22030.1 - 0.021 14.5 3.3 0.59 9.8 1.1 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Snapin_Pallidin PF14712.6 GAM22030.1 - 0.067 13.6 6.0 0.041 14.3 3.5 1.9 2 0 0 2 2 2 0 Snapin/Pallidin RPW8 PF05659.11 GAM22030.1 - 0.073 12.8 2.8 0.3 10.8 1.2 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Baculo_PEP_C PF04513.12 GAM22030.1 - 0.19 11.7 10.8 0.063 13.3 7.8 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rootletin PF15035.6 GAM22030.1 - 0.32 11.0 4.8 0.078 13.0 1.5 1.6 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Syntaxin-6_N PF09177.11 GAM22030.1 - 2.1 9.0 8.6 51 4.5 0.0 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Sec20 PF03908.13 GAM22030.1 - 2.3 8.2 9.7 0.74 9.8 4.2 2.8 3 0 0 3 3 3 0 Sec20 FNIP PF05725.12 GAM22031.1 - 1.5e-106 348.3 32.0 9.3e-16 57.7 0.1 10.1 3 2 8 13 13 13 12 FNIP Repeat LRR_1 PF00560.33 GAM22031.1 - 2.7 8.9 9.6 19 6.3 0.1 5.7 5 2 0 5 5 5 0 Leucine Rich Repeat MBOAT PF03062.19 GAM22032.1 - 7.2e-45 153.8 12.5 7.2e-45 153.8 12.5 1.9 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family RRM_1 PF00076.22 GAM22035.1 - 6.9e-17 61.0 0.0 6.4e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.22 GAM22035.1 - 3.2e-12 46.3 0.0 6.8e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain Limkain-b1 PF11608.8 GAM22035.1 - 0.0063 16.6 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 1 Limkain b1 Cupin_4 PF08007.12 GAM22035.1 - 0.069 12.6 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 Cupin superfamily protein Nup35_RRM_2 PF14605.6 GAM22035.1 - 0.094 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Beach PF02138.18 GAM22037.1 - 4.2e-117 390.4 2.6 6.5e-117 389.8 2.6 1.3 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 GAM22037.1 - 2.5e-21 76.1 0.7 1e-20 74.1 0.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 GAM22037.1 - 2.5e-19 69.2 0.1 1.2e-18 67.1 0.0 2.3 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 GAM22037.1 - 1.6e-10 41.4 0.0 5.1e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 GAM22037.1 - 3.2e-05 24.6 4.8 0.027 15.4 0.3 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat GRAM PF02893.20 GAM22037.1 - 8.2e-05 22.5 0.0 0.00024 20.9 0.0 1.8 1 0 0 1 1 1 1 GRAM domain ANAPC4_WD40 PF12894.7 GAM22037.1 - 0.15 12.4 0.0 12 6.2 0.0 3.1 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CD36 PF01130.21 GAM22039.1 - 8.5e-61 205.9 9.0 5.5e-36 124.1 0.3 2.2 2 0 0 2 2 2 2 CD36 family PorA PF11271.8 GAM22039.1 - 0.029 13.7 1.3 0.14 11.5 1.3 2.0 1 1 0 1 1 1 0 Porin PorA Sugar_tr PF00083.24 GAM22040.1 - 4.4e-70 236.8 36.2 9.9e-41 140.0 17.3 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM22040.1 - 4.2e-22 78.5 37.1 1.7e-15 56.8 11.9 3.1 1 1 1 3 3 3 2 Major Facilitator Superfamily Ribosomal_L14e PF01929.17 GAM22040.1 - 0.07 13.6 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L14 RNase_J_C PF17770.1 GAM22040.1 - 0.14 13.2 0.3 1.5 10.0 0.2 2.3 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain MFS_3 PF05977.13 GAM22040.1 - 0.5 8.7 16.9 0.71 8.2 6.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Rick_17kDa_Anti PF05433.15 GAM22040.1 - 3.4 7.6 17.0 0.21 11.5 10.2 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain ubiquitin PF00240.23 GAM22041.1 - 1.3e-22 79.4 0.3 2.2e-22 78.6 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM22041.1 - 5.2e-10 39.0 0.2 9.5e-10 38.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 GAM22041.1 - 6.1e-10 38.8 0.1 2e-09 37.1 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain STI1 PF17830.1 GAM22041.1 - 2.7e-05 24.0 49.3 0.00034 20.5 5.0 5.8 2 2 2 4 4 4 3 STI1 domain Ubiquitin_2 PF14560.6 GAM22041.1 - 0.00019 21.8 0.3 0.00051 20.4 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 GAM22041.1 - 0.0004 20.9 0.0 0.0012 19.4 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 GAM22041.1 - 0.0041 17.0 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAM22041.1 - 0.0086 16.1 0.6 1.3 9.2 0.1 2.4 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 GAM22041.1 - 0.017 15.5 0.1 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain HECW1_helix PF18436.1 GAM22041.1 - 0.023 14.8 6.2 3.1 8.0 0.3 3.5 2 1 1 3 3 3 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 Pik1 PF11522.8 GAM22041.1 - 0.023 14.6 0.2 0.11 12.5 0.1 2.3 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 CUE PF02845.16 GAM22041.1 - 0.027 14.2 0.5 0.027 14.2 0.5 2.3 2 0 0 2 2 2 0 CUE domain Rad60-SLD_2 PF13881.6 GAM22041.1 - 0.031 14.4 0.0 0.078 13.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 GAM22041.1 - 0.056 13.4 0.1 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 HOIP UBA domain pair UN_NPL4 PF11543.8 GAM22041.1 - 0.071 13.6 0.2 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 LPD22 PF18834.1 GAM22041.1 - 0.29 11.4 4.9 12 6.2 0.2 3.2 3 0 0 3 3 3 0 Large polyvalent protein associated domain 22 BSD PF03909.17 GAM22041.1 - 1.4 9.0 5.7 1.1 9.3 0.5 3.3 3 1 0 3 3 3 0 BSD domain XPC-binding PF09280.11 GAM22041.1 - 2.4 8.0 33.5 1.5 8.6 4.8 6.4 4 2 1 5 5 5 0 XPC-binding domain Com_YlbF PF06133.11 GAM22041.1 - 5 7.8 10.2 6.8 7.3 0.3 3.3 2 1 1 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA CCDC53 PF10152.9 GAM22042.1 - 2.2e-42 145.1 3.1 2.6e-41 141.6 0.0 3.1 2 2 1 3 3 3 1 Subunit CCDC53 of WASH complex DNA_pol_phi PF04931.13 GAM22042.1 - 0.018 13.2 13.0 0.024 12.8 13.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GAM22042.1 - 9.7 4.6 8.1 13 4.1 8.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ras PF00071.22 GAM22043.1 - 7.3e-43 146.0 0.0 1.5e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAM22043.1 - 1.4e-16 60.8 0.3 1.1e-08 35.3 0.0 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase PH PF00169.29 GAM22043.1 - 1e-09 38.9 1.7 1e-09 38.8 0.3 1.8 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 GAM22043.1 - 1.9e-05 24.9 0.0 4.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain MMR_HSR1 PF01926.23 GAM22043.1 - 0.0079 16.3 0.0 0.032 14.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase PH_5 PF15405.6 GAM22043.1 - 0.021 14.9 0.2 0.021 14.9 0.2 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 GAM22043.1 - 0.11 12.9 0.9 0.61 10.5 0.9 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain ABC_membrane PF00664.23 GAM22044.1 - 1.7e-15 57.4 21.5 4.1e-11 43.0 11.4 2.5 1 1 1 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM22044.1 - 9.6e-11 42.3 0.0 9.6e-11 42.3 0.0 2.3 2 1 0 2 2 2 1 ABC transporter UL45 PF05473.12 GAM22044.1 - 0.026 14.1 0.3 0.05 13.2 0.3 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like PBP1_TM PF14812.6 GAM22044.1 - 7.8 6.9 9.6 1 9.8 4.8 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NTP_transf_7 PF07984.12 GAM22045.1 - 2.3e-31 109.2 4.8 5.2e-24 85.1 2.0 2.2 2 0 0 2 2 2 2 Nucleotidyltransferase BNIP2 PF12496.8 GAM22045.1 - 0.077 13.4 0.1 0.37 11.2 0.1 2.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 COX15-CtaA PF02628.15 GAM22046.1 - 9.8e-111 369.9 5.6 1.2e-110 369.6 5.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Protamine_P2 PF00841.19 GAM22046.1 - 0.11 12.9 2.1 0.21 12.1 2.1 1.3 1 0 0 1 1 1 0 Sperm histone P2 Rep_4 PF05797.11 GAM22046.1 - 0.17 11.0 0.2 0.24 10.5 0.2 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) SprA-related PF12118.8 GAM22046.1 - 0.25 10.4 7.5 0.37 9.9 7.5 1.1 1 0 0 1 1 1 0 SprA-related family Coilin_N PF15862.5 GAM22046.1 - 2.4 8.0 5.6 3.9 7.3 5.6 1.2 1 0 0 1 1 1 0 Coilin N-terminus FAT PF02259.23 GAM22047.1 - 1.9e-109 366.1 0.5 1.9e-109 366.1 0.5 2.5 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 GAM22047.1 - 1.8e-72 244.2 0.5 4.6e-72 242.8 0.4 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 GAM22047.1 - 7.4e-65 217.8 5.3 7.7e-61 204.7 0.0 5.7 5 2 1 6 6 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 GAM22047.1 - 4.1e-42 142.6 0.3 4.1e-42 142.6 0.3 3.8 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 GAM22047.1 - 2.4e-19 69.5 14.4 0.0012 19.2 0.0 10.3 8 2 3 11 11 10 5 HEAT repeats HEAT PF02985.22 GAM22047.1 - 5e-15 54.3 21.6 0.0046 17.1 0.0 13.8 14 0 0 14 14 13 2 HEAT repeat FATC PF02260.20 GAM22047.1 - 7e-15 54.6 2.7 1.1e-14 53.9 0.4 2.4 2 0 0 2 2 2 1 FATC domain Cnd1 PF12717.7 GAM22047.1 - 9.8e-14 51.7 0.5 0.00079 19.5 0.0 5.6 3 1 1 5 5 5 4 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAM22047.1 - 1.4e-09 37.1 6.8 4.7e-07 28.7 0.1 4.3 4 1 0 4 4 4 2 Adaptin N terminal region HEAT_EZ PF13513.6 GAM22047.1 - 7.1e-09 36.0 16.7 0.00042 20.8 0.1 10.2 9 2 2 11 11 10 2 HEAT-like repeat UME PF08064.13 GAM22047.1 - 1.8e-07 31.0 3.9 0.25 11.3 0.1 6.9 7 1 0 7 7 7 2 UME (NUC010) domain Sec7_N PF12783.7 GAM22047.1 - 5.4e-07 29.6 2.7 0.095 12.6 0.0 4.7 4 1 0 4 4 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.7 GAM22047.1 - 0.00017 22.1 1.5 41 4.9 0.0 6.2 6 1 0 6 6 5 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 GAM22047.1 - 0.0022 17.1 0.4 0.31 10.1 0.0 4.2 4 1 1 5 5 5 1 Interferon-related developmental regulator (IFRD) ParcG PF10274.9 GAM22047.1 - 0.0027 17.8 10.2 0.18 11.9 0.1 5.7 5 2 1 6 6 6 1 Parkin co-regulated protein CLASP_N PF12348.8 GAM22047.1 - 0.0034 17.0 1.5 0.32 10.5 0.0 4.7 5 1 0 5 5 5 1 CLASP N terminal RNase_H2-Ydr279 PF09468.10 GAM22047.1 - 0.0046 17.2 0.0 0.018 15.2 0.0 2.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain TPR_19 PF14559.6 GAM22047.1 - 0.051 14.1 0.1 1.9 9.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Tti2 PF10521.9 GAM22047.1 - 0.08 12.5 7.4 12 5.3 0.0 4.8 4 1 1 5 5 5 0 Tti2 family TPR_7 PF13176.6 GAM22047.1 - 0.12 12.5 2.4 1.2 9.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ADH_N_2 PF16884.5 GAM22048.1 - 1.2e-42 144.2 0.0 2.2e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 GAM22048.1 - 1.1e-20 73.9 0.1 1.7e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM22048.1 - 3.3e-10 41.1 0.0 7.1e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Vault PF01505.18 GAM22049.1 - 1.2e-61 204.6 0.6 1.6e-15 57.0 0.0 5.1 5 0 0 5 5 5 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 GAM22049.1 - 5.9e-53 177.9 0.4 1.1e-52 177.1 0.4 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 GAM22049.1 - 2.5e-39 133.5 0.1 1.8e-24 85.9 0.0 2.6 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 GAM22049.1 - 2.1e-34 117.4 0.2 4.3e-30 103.5 0.0 3.4 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 GAM22049.1 - 9.8e-23 80.0 0.0 7.6e-22 77.2 0.0 2.6 2 0 0 2 2 2 1 Major Vault Protein repeat domain DUF3601 PF12208.8 GAM22049.1 - 0.063 13.4 0.0 7.1 6.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3601) T2SSI PF02501.17 GAM22049.1 - 0.083 13.1 3.7 0.56 10.4 0.1 3.1 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein I Frizzled PF01534.17 GAM22050.1 - 1.3e-08 34.3 10.1 1.9e-08 33.7 10.1 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 GAM22050.1 - 4.2e-08 32.8 9.6 4.2e-08 32.8 9.6 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 GAM22050.1 - 4.9e-07 29.2 11.2 8e-07 28.5 11.2 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor MerT PF02411.15 GAM22050.1 - 0.017 15.1 0.9 0.051 13.6 0.9 1.8 1 0 0 1 1 1 0 MerT mercuric transport protein 7TM_GPCR_Str PF10326.9 GAM22050.1 - 0.61 9.4 12.3 0.036 13.4 6.6 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str PTR2 PF00854.21 GAM22051.1 - 2.1e-94 316.6 11.0 2.1e-94 316.6 11.0 2.0 1 1 1 2 2 2 2 POT family DUF2070 PF09843.9 GAM22051.1 - 0.00065 18.1 21.6 0.0027 16.1 2.5 2.3 2 1 0 2 2 2 2 Predicted membrane protein (DUF2070) HVSL PF09749.9 GAM22052.1 - 2.3e-36 125.5 0.5 3.5e-36 124.9 0.5 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 GAM22052.1 - 9e-05 22.4 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 GAM22052.1 - 0.096 12.9 0.0 0.54 10.5 0.1 2.0 2 0 0 2 2 2 0 LigT like Phosphoesterase CDC45 PF02724.14 GAM22052.1 - 0.49 8.6 8.3 0.65 8.2 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MIF4G_like_2 PF09090.11 GAM22055.1 - 1.2e-35 123.3 0.8 1.2e-35 123.3 0.8 1.9 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.11 GAM22055.1 - 1.7e-29 103.0 2.6 2.1e-28 99.4 1.9 2.5 1 1 1 2 2 2 1 MIF4G like MIF4G PF02854.19 GAM22055.1 - 1.5e-16 60.7 5.9 5.1e-16 59.0 4.1 2.5 2 0 0 2 2 2 1 MIF4G domain IFRD PF05004.13 GAM22055.1 - 0.045 12.9 0.9 0.33 10.0 0.2 2.3 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) DUF1054 PF06335.12 GAM22055.1 - 0.087 12.7 2.3 0.08 12.9 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) MG1 PF17790.1 GAM22055.1 - 0.12 12.8 0.7 2.2 8.7 0.1 2.9 3 0 0 3 3 3 0 Macroglobulin domain MG1 Caps_synth_GfcC PF06251.11 GAM22055.1 - 0.25 10.9 2.4 0.65 9.6 0.2 2.2 1 1 1 2 2 2 0 Capsule biosynthesis GfcC LRR_6 PF13516.6 GAM22056.1 - 3.7e-14 51.5 74.9 0.065 13.3 0.6 15.1 15 0 0 15 15 15 9 Leucine Rich repeat LRR_4 PF12799.7 GAM22056.1 - 2.2e-05 24.7 67.2 0.048 14.1 0.4 11.1 7 4 5 12 12 12 8 Leucine Rich repeats (2 copies) DS PF01916.17 GAM22056.1 - 0.049 12.9 0.6 0.28 10.4 0.1 2.0 1 1 0 2 2 2 0 Deoxyhypusine synthase DUF2688 PF10892.8 GAM22056.1 - 0.075 12.5 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) LRR_8 PF13855.6 GAM22056.1 - 0.12 12.2 75.3 0.15 11.9 2.8 10.9 7 5 1 9 9 9 0 Leucine rich repeat LRR_1 PF00560.33 GAM22056.1 - 5.6 7.9 41.8 17 6.5 0.2 12.1 13 3 0 13 13 13 0 Leucine Rich Repeat AAA_23 PF13476.6 GAM22057.1 - 9.2e-31 107.9 4.4 9.2e-31 107.9 4.4 7.8 1 1 5 6 6 3 1 AAA domain AAA_21 PF13304.6 GAM22057.1 - 2.2e-12 47.4 6.8 1.7e-06 28.1 0.1 3.7 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad50_zn_hook PF04423.14 GAM22057.1 - 1e-06 28.4 0.4 3.7e-05 23.5 0.2 4.2 2 0 0 2 2 2 1 Rad50 zinc hook motif AAA_15 PF13175.6 GAM22057.1 - 5.2e-05 23.1 51.1 0.00036 20.4 14.3 5.5 1 1 2 4 4 3 2 AAA ATPase domain SMC_N PF02463.19 GAM22057.1 - 0.0003 20.3 50.3 0.0024 17.4 50.3 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 GAM22057.1 - 0.00034 20.8 0.0 0.0011 19.1 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF1664 PF07889.12 GAM22057.1 - 0.0018 18.3 8.3 0.0018 18.3 8.3 12.6 4 2 10 15 15 15 5 Protein of unknown function (DUF1664) AAA_13 PF13166.6 GAM22057.1 - 0.0039 15.9 123.9 0.0073 15.0 0.0 7.7 1 1 8 9 9 9 3 AAA domain AAA_29 PF13555.6 GAM22057.1 - 0.0045 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 GAM22057.1 - 0.0074 16.8 0.0 0.0074 16.8 0.0 8.1 2 1 0 3 3 1 1 ABC transporter AAA_16 PF13191.6 GAM22057.1 - 0.16 12.3 0.1 0.16 12.3 0.1 5.3 4 3 0 4 4 2 0 AAA ATPase domain Methyltransf_12 PF08242.12 GAM22057.1 - 0.25 12.1 2.8 49 4.8 0.1 3.8 2 0 0 2 2 2 0 Methyltransferase domain AAA_22 PF13401.6 GAM22057.1 - 1.2 9.4 0.0 1.2 9.4 0.0 5.0 6 0 0 6 6 6 0 AAA domain MAT1 PF06391.13 GAM22058.1 - 5e-32 111.4 21.8 6.6e-32 111.0 21.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 GAM22058.1 - 5.3e-08 32.6 2.4 5.3e-08 32.6 2.4 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM22058.1 - 6.2e-07 29.3 3.1 2.5e-06 27.4 3.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAM22058.1 - 0.0001 22.2 7.6 0.00094 19.1 8.3 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAM22058.1 - 0.00012 21.9 8.1 0.00093 19.0 8.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM22058.1 - 0.00012 21.8 3.7 0.00038 20.2 3.7 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAM22058.1 - 0.00013 22.2 6.5 0.00042 20.6 6.8 1.7 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 GAM22058.1 - 0.00033 20.4 9.3 0.00066 19.5 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM22058.1 - 0.011 15.5 6.9 0.037 13.9 7.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAM22058.1 - 0.02 15.0 7.0 0.041 14.1 7.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 GAM22058.1 - 0.029 14.1 3.4 0.029 14.1 3.4 1.9 2 0 0 2 2 2 0 RING-like zinc finger DUF2318 PF10080.9 GAM22058.1 - 0.033 14.3 4.0 0.5 10.5 1.1 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Prok-RING_1 PF14446.6 GAM22058.1 - 0.099 12.6 0.7 0.099 12.6 0.7 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 GAM22058.1 - 0.13 12.6 2.6 0.34 11.2 2.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 GAM22058.1 - 0.52 10.5 4.8 1.6 9.0 4.7 1.8 1 1 0 1 1 1 0 FYVE zinc finger Zn_ribbon_17 PF17120.5 GAM22058.1 - 0.69 9.6 3.5 1.3 8.7 3.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ribosomal_L5e PF17144.4 GAM22059.1 - 2.9e-82 274.5 0.4 4.5e-82 273.9 0.4 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 GAM22059.1 - 6.9e-29 100.6 2.7 6.9e-29 100.6 2.7 2.2 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 GAM22059.1 - 0.066 13.4 0.0 0.66 10.2 0.0 2.4 1 1 1 2 2 2 0 Threonine synthase N terminus EGF_2 PF07974.13 GAM22061.1 - 4.1e-05 23.9 11.6 7e-05 23.1 11.6 1.4 1 0 0 1 1 1 1 EGF-like domain Podoplanin PF05808.11 GAM22061.1 - 0.017 15.2 0.7 0.058 13.5 0.4 1.8 1 1 0 1 1 1 0 Podoplanin DUF3139 PF11337.8 GAM22061.1 - 0.12 13.1 1.0 21 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) hEGF PF12661.7 GAM22061.1 - 1.6 9.5 8.1 3.7 8.3 8.1 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.27 GAM22061.1 - 1.9 8.9 8.5 3.4 8.1 8.5 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 GAM22062.1 - 0.0049 17.2 13.3 0.0049 17.2 13.3 1.7 2 0 0 2 2 2 1 EGF-like domain Podoplanin PF05808.11 GAM22062.1 - 0.047 13.8 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Podoplanin Transthyretin PF00576.21 GAM22062.1 - 0.12 13.1 0.0 0.34 11.6 0.0 1.8 1 0 0 1 1 1 0 HIUase/Transthyretin family Phage_holin_2_4 PF16082.5 GAM22062.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like EGF PF00008.27 GAM22062.1 - 0.78 10.1 9.5 1.5 9.2 9.5 1.5 1 0 0 1 1 1 0 EGF-like domain Vpu PF00558.19 GAM22062.1 - 0.91 9.3 2.6 1.9 8.3 2.6 1.5 1 0 0 1 1 1 0 Vpu protein EGF_2 PF07974.13 GAM22063.1 - 0.0059 17.0 10.6 0.012 16.0 10.6 1.6 1 0 0 1 1 1 1 EGF-like domain Kelch_6 PF13964.6 GAM22064.1 - 6.3e-15 54.8 6.3 0.00053 20.2 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 GAM22064.1 - 1.5e-12 46.9 2.5 0.0018 17.8 0.0 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM22064.1 - 5.3e-11 42.3 13.1 0.0024 17.8 0.2 5.2 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM22064.1 - 3e-07 30.5 0.6 0.13 12.6 0.1 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM22064.1 - 0.0027 17.6 6.6 8.3 6.6 0.0 4.8 5 1 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 GAM22064.1 - 0.03 14.3 4.4 6.1 6.9 0.1 3.7 3 0 0 3 3 3 0 Kelch motif FPP PF05911.11 GAM22064.1 - 0.94 7.6 5.8 1.3 7.1 5.8 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil GFA PF04828.14 GAM22065.1 - 7.4e-06 26.2 2.3 7.7e-06 26.2 0.6 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-ZPR1 PF03367.13 GAM22065.1 - 0.02 14.8 0.1 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 ZPR1 zinc-finger domain FNIP PF05725.12 GAM22066.1 - 1.5e-13 50.7 4.3 3.9e-09 36.5 1.3 3.2 2 1 1 3 3 3 2 FNIP Repeat zf-C3HC4_2 PF13923.6 GAM22066.1 - 0.032 14.1 1.6 0.032 14.1 1.6 2.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM22066.1 - 0.074 13.0 6.5 0.27 11.2 6.5 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Cys_rich_CWC PF14375.6 GAM22066.1 - 1.9 8.9 7.0 0.17 12.3 2.0 1.8 2 0 0 2 2 2 0 Cysteine-rich CWC zf-C3HC4_2 PF13923.6 GAM22067.1 - 0.0069 16.2 2.5 0.0069 16.2 2.5 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) GFA PF04828.14 GAM22067.1 - 0.011 16.1 5.6 0.011 16.1 5.6 1.7 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-RING_2 PF13639.6 GAM22067.1 - 0.11 12.9 1.3 0.11 12.9 1.3 2.9 3 1 1 4 4 4 0 Ring finger domain CEBP_ZZ PF16366.5 GAM22067.1 - 0.14 12.4 8.8 0.21 11.9 8.1 1.7 1 1 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain PYRIN PF02758.16 GAM22067.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain zf-RING_5 PF14634.6 GAM22067.1 - 0.3 11.1 13.3 0.11 12.5 9.0 2.5 3 1 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAM22067.1 - 0.46 10.4 9.5 1 9.3 1.5 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 GAM22067.1 - 7.6 6.8 11.6 0.14 12.3 2.3 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 GFA PF04828.14 GAM22068.1 - 0.0018 18.6 2.9 0.0018 18.6 2.9 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PI3K_rbd PF00794.18 GAM22068.1 - 0.018 15.2 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain RCC1 PF00415.18 GAM22069.1 - 8.3e-65 215.2 9.7 4.9e-13 49.5 0.0 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM22069.1 - 4.8e-39 131.4 31.9 2.3e-09 36.8 0.1 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 GAM22069.1 - 1.4e-19 70.4 2.7 1.6e-15 57.2 0.6 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 GAM22069.1 - 6.2e-08 32.8 0.1 1.5e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM22069.1 - 5.4e-05 23.7 0.1 0.019 15.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM22069.1 - 9e-05 23.0 0.0 0.00063 20.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM22069.1 - 0.0036 17.7 0.0 0.012 16.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Mucin PF01456.17 GAM22069.1 - 0.014 15.4 7.7 0.034 14.1 7.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Ank PF00023.30 GAM22069.1 - 0.059 13.8 0.1 0.37 11.3 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ceramidase PF05875.12 GAM22071.1 - 1.4e-39 136.1 12.6 2.8e-39 135.2 12.6 1.4 1 0 0 1 1 1 1 Ceramidase EGF PF00008.27 GAM22071.1 - 2.3 8.6 10.0 4.9 7.5 10.0 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 GAM22071.1 - 4.3 7.8 21.9 0.055 13.8 14.4 1.8 2 0 0 2 2 2 0 EGF-like domain ANAPC4_WD40 PF12894.7 GAM22072.1 - 6.7e-11 42.3 0.3 0.0001 22.5 0.0 4.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM22072.1 - 4.9e-09 36.7 3.7 0.0011 19.7 0.3 5.6 5 1 0 5 5 5 1 WD domain, G-beta repeat eIF2A PF08662.11 GAM22072.1 - 8.5e-06 25.8 0.1 0.017 15.0 0.0 3.2 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 GAM22072.1 - 0.0021 16.7 0.1 4.5 5.7 0.0 3.0 2 1 1 3 3 3 2 Cytochrome D1 heme domain WD40_like PF17005.5 GAM22072.1 - 0.0073 15.7 0.1 0.64 9.3 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain Coatomer_WDAD PF04053.14 GAM22072.1 - 0.036 13.1 0.0 0.24 10.4 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region Glu_cyclase_2 PF05096.12 GAM22072.1 - 0.06 12.8 0.1 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Glutamine cyclotransferase ELYS-bb PF16687.5 GAM22072.1 - 0.073 11.7 0.0 0.45 9.1 0.0 2.0 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin Hira PF07569.11 GAM22072.1 - 0.11 12.2 1.4 4.6 6.9 0.1 2.6 2 1 1 3 3 3 0 TUP1-like enhancer of split VASt PF16016.5 GAM22074.1 - 1.2e-34 119.9 1.0 1.2e-34 119.9 1.0 3.2 3 0 0 3 3 3 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 GAM22074.1 - 1.2e-15 57.3 1.4 2.3e-15 56.5 0.2 2.0 2 0 0 2 2 2 1 GRAM domain MSC PF09402.10 GAM22074.1 - 0.046 13.2 0.1 0.046 13.2 0.1 2.0 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain SUIM_assoc PF16619.5 GAM22074.1 - 0.16 12.0 21.8 0.68 10.0 6.6 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ABC2_membrane_3 PF12698.7 GAM22074.1 - 2.9 6.9 12.3 1.7 7.7 0.2 2.7 3 0 0 3 3 3 0 ABC-2 family transporter protein HEM4 PF02602.15 GAM22075.1 - 2e-25 89.5 0.0 2.5e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD G-alpha PF00503.20 GAM22076.1 - 3.3e-68 230.4 1.4 4e-68 230.2 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM22076.1 - 1.8e-08 34.0 1.2 3.5e-05 23.3 0.1 2.8 2 1 1 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM22076.1 - 0.00067 19.1 0.5 1 8.7 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM22076.1 - 0.014 15.6 0.3 1.8 8.8 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DAP3 PF10236.9 GAM22076.1 - 0.024 13.8 0.2 0.043 13.0 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MMR_HSR1 PF01926.23 GAM22076.1 - 0.024 14.7 0.1 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 GAM22076.1 - 0.044 13.5 0.2 0.11 12.2 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMACHC PF16690.5 GAM22077.1 - 6.7e-15 55.3 0.4 1.5e-14 54.2 0.4 1.5 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family DUF3235 PF11574.8 GAM22077.1 - 0.13 13.1 0.0 0.46 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Dyp_perox PF04261.12 GAM22079.1 - 1.5e-80 270.7 0.0 2e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family DUF3430 PF11912.8 GAM22080.1 - 0.0043 17.1 1.9 0.0043 17.1 1.9 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3430) Sld5 PF05916.11 GAM22081.1 - 0.0012 19.2 0.1 0.0019 18.6 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein PCRF PF03462.18 GAM22082.1 - 1.3e-46 159.0 2.0 1.3e-46 159.0 2.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 GAM22082.1 - 3.1e-35 120.6 2.2 3.1e-35 120.6 2.2 1.8 2 0 0 2 2 2 1 RF-1 domain DUF2205 PF10224.9 GAM22082.1 - 0.011 15.7 3.2 0.022 14.7 3.2 1.5 1 0 0 1 1 1 0 Short coiled-coil protein SdpI PF13630.6 GAM22083.1 - 0.00089 19.3 0.7 0.00089 19.3 0.7 2.6 2 1 1 3 3 3 1 SdpI/YhfL protein family Rhomboid PF01694.22 GAM22083.1 - 0.0021 18.1 7.0 0.0073 16.3 7.0 1.8 1 1 0 1 1 1 1 Rhomboid family DUF1600 PF07667.11 GAM22083.1 - 0.003 17.7 6.5 0.003 17.7 6.5 1.6 1 1 0 2 2 2 1 Protein of unknown function (DUF1600) DUF1422 PF07226.11 GAM22083.1 - 0.043 13.8 2.3 0.08 13.0 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) DUF202 PF02656.15 GAM22083.1 - 0.068 13.6 0.3 0.068 13.6 0.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) LRR19-TM PF15176.6 GAM22083.1 - 0.22 11.5 1.8 0.55 10.3 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain PAP2_3 PF14378.6 GAM22083.1 - 0.53 9.9 7.2 0.059 13.1 2.0 1.8 1 1 1 2 2 2 0 PAP2 superfamily CD20 PF04103.15 GAM22083.1 - 0.61 10.2 9.6 2.5 8.2 9.5 2.1 1 1 0 1 1 1 0 CD20-like family PspC PF04024.12 GAM22083.1 - 0.83 9.5 8.5 3.2 7.6 0.1 2.8 3 0 0 3 3 3 0 PspC domain Na_Ca_ex PF01699.24 GAM22083.1 - 2 8.3 13.7 2.4 8.1 9.2 2.4 1 1 2 3 3 3 0 Sodium/calcium exchanger protein DUF308 PF03729.13 GAM22083.1 - 2.2 8.7 13.7 0.16 12.3 2.8 2.9 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) DUF2070 PF09843.9 GAM22083.1 - 4.8 5.3 10.8 7.5 4.7 10.8 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Tetraspanin PF00335.20 GAM22083.1 - 6.5 6.4 14.0 15 5.3 14.0 1.7 1 1 0 1 1 1 0 Tetraspanin family Isy1 PF06246.12 GAM22084.1 - 7.1e-79 265.0 14.8 8e-79 264.8 14.8 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Brix PF04427.18 GAM22085.1 - 1.8e-42 145.6 0.5 3.1e-42 144.9 0.5 1.3 1 0 0 1 1 1 1 Brix domain Motilin_ghrelin PF04644.12 GAM22085.1 - 1.5 8.7 11.6 4.9 7.0 11.6 1.9 1 0 0 1 1 1 0 Motilin/ghrelin IMPDH PF00478.25 GAM22085.1 - 5.8 5.8 7.3 0.16 10.9 0.4 1.7 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain CDC45 PF02724.14 GAM22086.1 - 0.00041 18.8 3.5 0.0005 18.5 3.5 1.1 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 GAM22086.1 - 0.0035 15.9 7.7 0.004 15.7 7.7 1.1 1 0 0 1 1 1 1 Mpp10 protein eIF-3c_N PF05470.12 GAM22086.1 - 0.008 14.5 1.4 0.0081 14.5 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4637 PF15470.6 GAM22086.1 - 0.25 11.1 3.3 0.38 10.5 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CNDH2_C PF16858.5 GAM22086.1 - 1.2 9.0 15.1 1.7 8.5 15.1 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term D123 PF07065.14 GAM22086.1 - 3.2 6.8 9.7 4.9 6.2 9.7 1.2 1 0 0 1 1 1 0 D123 Metallophos PF00149.28 GAM22088.1 - 6.3e-10 39.9 0.0 1.1e-09 39.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM22088.1 - 1.6e-05 25.1 0.0 0.088 13.0 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain ASF1_hist_chap PF04729.13 GAM22089.1 - 2.1e-64 216.1 0.0 2.3e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Zip PF02535.22 GAM22090.1 - 1.8e-44 152.4 13.6 3.6e-44 151.3 13.6 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Metallophos PF00149.28 GAM22091.1 - 2.8e-35 122.7 0.6 4.3e-35 122.1 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAM22091.1 - 0.00018 21.9 0.1 0.00036 20.9 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 GAM22091.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain zf-HYPF PF07503.12 GAM22091.1 - 0.068 13.0 0.9 1.3 8.8 0.0 2.8 2 0 0 2 2 2 0 HypF finger CDC45 PF02724.14 GAM22092.1 - 1.7e-172 575.0 12.7 3.7e-172 574.0 12.7 1.5 1 1 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 GAM22092.1 - 0.0059 16.1 24.2 0.0084 15.6 24.2 1.2 1 0 0 1 1 1 1 SDA1 Protamine_P2 PF00841.19 GAM22092.1 - 0.0067 16.9 5.0 0.013 15.9 5.0 1.5 1 0 0 1 1 1 1 Sperm histone P2 YL1 PF05764.13 GAM22092.1 - 0.076 13.1 28.6 0.12 12.5 28.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 GAM22092.1 - 0.2 9.9 26.9 0.28 9.4 26.9 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 GAM22092.1 - 0.39 10.1 23.3 0.58 9.5 23.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 GAM22092.1 - 0.4 10.6 34.1 0.5 10.3 32.0 1.9 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Lin-8 PF03353.15 GAM22092.1 - 1.6 8.2 17.0 3.2 7.2 17.0 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sporozoite_P67 PF05642.11 GAM22092.1 - 7.1 4.6 7.5 12 3.8 7.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ank_4 PF13637.6 GAM22093.1 - 1.7e-18 66.7 9.4 0.00011 22.7 0.2 7.1 6 2 1 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM22093.1 - 1.1e-16 61.1 6.2 4.6e-07 30.3 1.4 4.7 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM22093.1 - 3.6e-11 43.1 14.3 0.39 11.1 0.5 8.6 4 3 4 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM22093.1 - 5.6e-10 38.6 9.0 1.8 9.4 0.1 8.8 10 0 0 10 10 10 3 Ankyrin repeat Ank PF00023.30 GAM22093.1 - 0.47 11.0 3.7 81 3.9 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeat zf-LITAF-like PF10601.9 GAM22094.1 - 2.7e-21 75.6 8.5 3.8e-21 75.1 8.5 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain HypA PF01155.19 GAM22094.1 - 0.0012 18.8 0.5 0.0016 18.4 0.5 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 GAM22094.1 - 0.054 12.9 4.0 3.7 7.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-UDP PF14569.6 GAM22094.1 - 0.087 13.0 1.5 0.19 11.9 1.5 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger Ogr_Delta PF04606.12 GAM22094.1 - 0.12 12.3 3.3 6.5 6.8 0.2 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger MPS-4 PF17523.2 GAM22094.1 - 0.3 11.2 0.7 0.48 10.6 0.7 1.3 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 RecR PF02132.15 GAM22094.1 - 3.4 7.3 6.6 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 RecR protein NFACT-R_1 PF05670.13 GAM22095.1 - 4.7e-45 152.7 0.7 1.1e-44 151.6 0.0 1.8 2 0 0 2 2 2 1 NFACT protein RNA binding domain Flagellar_put PF12611.8 GAM22095.1 - 0.019 14.7 0.6 0.044 13.6 0.6 1.6 1 0 0 1 1 1 0 Putative flagellar Kelch_6 PF13964.6 GAM22096.1 - 1.2e-09 38.1 5.4 0.00011 22.4 0.1 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM22096.1 - 0.0035 17.3 10.1 0.0038 17.2 0.0 3.7 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM22096.1 - 0.014 15.7 2.1 5.3 7.4 0.4 3.2 3 1 0 3 3 3 0 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM22096.1 - 0.99 9.5 3.3 13 6.0 0.7 3.6 3 1 0 3 3 3 0 Kelch motif Kelch_1 PF01344.25 GAM22096.1 - 2.2 7.9 11.3 2.2 7.9 0.0 4.1 4 1 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 GAM22097.1 - 2.1e-09 37.3 1.8 0.0012 19.1 0.1 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 GAM22097.1 - 8.7e-08 32.1 3.4 0.0012 18.8 0.2 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM22097.1 - 0.00033 20.2 1.8 1.8 8.2 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAM22097.1 - 0.0067 16.4 0.8 6.8 6.8 0.0 3.9 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 GAM22097.1 - 0.032 14.2 0.6 0.32 11.0 0.1 2.7 2 0 0 2 2 2 0 Kelch motif Pkinase PF00069.25 GAM22098.1 - 7.7e-61 205.8 0.0 1e-60 205.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22098.1 - 1.4e-49 168.8 0.0 2.4e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM22098.1 - 0.00053 19.4 0.0 0.0036 16.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAM22098.1 - 0.015 14.1 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 GAM22098.1 - 0.14 11.7 0.1 0.39 10.3 0.1 1.6 1 1 1 2 2 2 0 RIO1 family FTA2 PF13095.6 GAM22098.1 - 0.16 11.6 0.0 8.5 5.9 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TMEM154 PF15102.6 GAM22101.1 - 0.046 13.6 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family TMEM144 PF07857.12 GAM22101.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters Maf PF02545.14 GAM22102.1 - 2.4e-52 177.2 0.0 2.7e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein AD PF09793.9 GAM22102.1 - 0.027 14.6 0.1 0.049 13.8 0.1 1.4 1 0 0 1 1 1 0 Anticodon-binding domain ATPase_2 PF01637.18 GAM22102.1 - 0.073 13.0 0.2 0.089 12.7 0.2 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Peptidase_C12 PF01088.21 GAM22103.1 - 1.6e-67 227.3 0.0 2.5e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 GAM22103.1 - 1e-18 66.9 4.0 2.2e-18 65.9 4.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases SAPIS-gp6 PF16722.5 GAM22103.1 - 0.057 13.8 4.0 0.15 12.5 0.5 2.5 1 1 1 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus GATase PF00117.28 GAM22105.1 - 3e-39 134.7 0.0 6.2e-39 133.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 GAM22105.1 - 3.1e-19 68.8 0.2 4.9e-12 45.7 0.0 3.4 2 1 0 2 2 2 2 GMP synthase C terminal domain Peptidase_C26 PF07722.13 GAM22105.1 - 5.6e-13 49.2 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 GAM22105.1 - 2.5e-10 39.9 0.2 2.2e-07 30.3 0.1 2.4 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 GAM22105.1 - 3.9e-07 29.8 0.1 2e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 GAM22105.1 - 3.6e-05 23.4 0.0 0.0001 22.0 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 GAM22105.1 - 3.8e-05 23.2 0.0 6.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.16 GAM22105.1 - 0.00012 21.0 0.0 0.0011 17.8 0.1 2.1 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.19 GAM22105.1 - 0.00064 19.8 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 GAM22105.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 PP-loop family Asn_synthase PF00733.21 GAM22105.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Asparagine synthase FNIP PF05725.12 GAM22106.1 - 7.4e-60 198.9 38.8 1.5e-14 53.9 0.6 9.4 5 2 2 8 8 8 7 FNIP Repeat DUF1769 PF08588.10 GAM22106.1 - 0.39 10.9 2.6 71 3.7 0.0 4.9 3 2 3 6 6 6 0 Protein of unknown function (DUF1769) Kelch_6 PF13964.6 GAM22107.1 - 6.1e-07 29.5 10.8 0.0035 17.6 0.2 5.3 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 GAM22107.1 - 0.0054 16.3 4.7 1.7 8.3 0.2 3.7 3 0 0 3 3 3 2 Kelch motif Tropomyosin_1 PF12718.7 GAM22107.1 - 0.079 13.1 0.9 0.18 12.0 0.2 1.8 2 0 0 2 2 2 0 Tropomyosin like DUF1664 PF07889.12 GAM22107.1 - 0.16 12.0 12.0 0.3 11.1 3.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Kelch_4 PF13418.6 GAM22107.1 - 0.19 11.8 0.2 0.19 11.8 0.2 5.0 5 1 0 5 5 5 0 Galactose oxidase, central domain DUF3439 PF11921.8 GAM22107.1 - 0.49 10.4 5.2 0.99 9.4 5.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ALIX_LYPXL_bnd PF13949.6 GAM22107.1 - 0.52 9.6 4.9 0.69 9.2 3.7 1.7 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV NPV_P10 PF05531.12 GAM22107.1 - 0.65 10.5 8.7 5 7.7 2.3 3.1 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ParB PF08775.10 GAM22107.1 - 0.91 10.0 8.1 0.35 11.4 3.0 2.6 1 1 2 3 3 3 0 ParB family Baculo_PEP_C PF04513.12 GAM22107.1 - 1.5 8.8 11.3 1.3 9.0 4.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 GAM22107.1 - 1.6 9.2 14.9 6.1 7.3 0.4 3.1 2 1 1 3 3 3 0 Syntaxin-like protein Kelch_4 PF13418.6 GAM22108.1 - 5e-11 42.4 1.2 0.0007 19.6 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM22108.1 - 2.7e-10 40.1 0.8 0.036 14.4 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 GAM22108.1 - 0.018 14.7 4.1 9.7 5.9 0.0 4.3 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.6 GAM22108.1 - 0.041 13.9 0.8 0.22 11.5 0.3 2.3 2 0 0 2 2 2 0 Kelch motif zf-B_box PF00643.24 GAM22108.1 - 0.047 13.9 5.2 0.1 12.7 5.2 1.6 1 0 0 1 1 1 0 B-box zinc finger Baculo_PEP_C PF04513.12 GAM22108.1 - 0.63 10.1 7.5 0.62 10.1 1.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 GAM22109.1 - 6.1e-78 261.8 0.0 6.9e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22109.1 - 1e-32 113.5 0.0 1.6e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM22109.1 - 8.1e-07 28.3 0.1 3.3e-05 23.0 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM22109.1 - 0.00014 21.9 0.0 0.005 16.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAM22109.1 - 0.0012 17.9 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 FTA2 PF13095.6 GAM22109.1 - 0.0039 16.8 0.1 0.092 12.4 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GAM22109.1 - 0.013 14.8 0.1 0.058 12.7 0.0 2.0 1 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 GAM22109.1 - 0.026 13.9 0.2 0.046 13.1 0.1 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Far-17a_AIG1 PF04750.14 GAM22110.1 - 5.2e-23 81.4 13.4 4.7e-22 78.3 13.4 1.9 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein DUF3742 PF12553.8 GAM22110.1 - 0.054 13.6 0.7 0.15 12.2 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) DUF2417 PF10329.9 GAM22110.1 - 6.5 6.1 9.4 0.9 8.9 3.3 2.1 2 0 0 2 2 2 0 Region of unknown function (DUF2417) I_LWEQ PF01608.17 GAM22111.1 - 3.5e-51 173.5 86.7 6.2e-46 156.4 15.1 8.4 3 2 2 7 7 7 4 I/LWEQ domain VHP PF02209.19 GAM22111.1 - 4.5e-15 55.4 3.0 1.2e-14 54.1 3.0 1.8 1 0 0 1 1 1 1 Villin headpiece domain VBS PF08913.10 GAM22111.1 - 7.3e-06 26.4 16.2 2.2e-05 24.9 5.1 6.9 7 0 0 7 7 7 4 Vinculin Binding Site DUF1771 PF08590.10 GAM22111.1 - 4.3 7.8 13.8 0.71 10.3 1.4 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) SipA_VBS PF17985.1 GAM22111.1 - 8.2 6.5 9.4 4.4 7.4 0.2 4.8 5 0 0 5 5 5 0 SipA vinculin binding site FERM_f0 PF16511.5 GAM22112.1 - 2.8e-29 101.2 0.0 7.1e-25 87.1 0.0 2.9 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 GAM22112.1 - 5.2e-27 94.6 0.1 5.2e-27 94.6 0.1 3.2 3 1 0 3 3 3 1 FERM central domain I_LWEQ PF01608.17 GAM22112.1 - 6.2e-20 72.0 100.0 0.00016 21.9 4.6 12.2 6 4 5 12 12 12 8 I/LWEQ domain FERM_N PF09379.10 GAM22112.1 - 2.7e-18 65.7 0.2 1.2e-17 63.6 0.1 2.2 2 0 0 2 2 2 1 FERM N-terminal domain VBS PF08913.10 GAM22112.1 - 0.0032 17.9 1.4 0.0032 17.9 1.4 9.4 5 2 3 9 9 9 3 Vinculin Binding Site PriX PF18689.1 GAM22112.1 - 0.0085 16.4 0.2 3.4 8.1 0.0 2.9 2 0 0 2 2 2 1 Primase X Focal_AT PF03623.13 GAM22112.1 - 0.013 15.5 29.0 0.015 15.3 1.6 7.7 5 2 2 8 8 8 0 Focal adhesion targeting region ACBP PF00887.19 GAM22112.1 - 0.032 14.4 0.5 0.22 11.8 0.0 2.8 2 0 0 2 2 2 0 Acyl CoA binding protein Vps52 PF04129.12 GAM22114.1 - 6e-80 269.4 30.9 6e-80 269.4 30.9 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family DUF1122 PF06557.11 GAM22114.1 - 0.0053 16.2 0.6 0.016 14.6 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1122) Cep57_MT_bd PF06657.13 GAM22114.1 - 0.03 14.8 0.9 0.11 13.0 0.9 2.0 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Sec3_C PF09763.9 GAM22114.1 - 0.03 12.7 35.1 0.69 8.2 26.4 4.0 1 1 1 2 2 2 0 Exocyst complex component Sec3 NBD94 PF16830.5 GAM22114.1 - 9 6.8 9.5 2 8.8 2.9 3.2 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH DHR-2 PF06920.13 GAM22115.1 - 5.4e-171 569.8 12.3 5.4e-171 569.8 12.3 1.9 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 GAM22115.1 - 1.3e-45 155.6 2.6 2.4e-45 154.7 1.2 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins TLE_N PF03920.15 GAM22115.1 - 0.04 14.0 2.3 0.17 12.0 1.4 2.5 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain FNIP PF05725.12 GAM22116.1 - 4.8e-13 49.0 0.7 6.1e-07 29.5 0.1 2.9 1 1 2 3 3 3 3 FNIP Repeat FNIP PF05725.12 GAM22117.1 - 1.4e-27 95.5 0.0 3.6e-09 36.6 0.1 3.8 2 1 2 5 5 5 4 FNIP Repeat Ank_3 PF13606.6 GAM22118.1 - 0.02 15.4 0.0 20 6.1 0.0 4.6 6 0 0 6 6 6 0 Ankyrin repeat Ank_4 PF13637.6 GAM22118.1 - 0.068 13.8 0.2 28 5.4 0.0 4.6 4 1 0 4 4 4 0 Ankyrin repeats (many copies) LPD26 PF18842.1 GAM22119.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 26 P21-Arc PF04062.14 GAM22120.1 - 7.7e-68 227.9 0.0 9.1e-68 227.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Pkinase PF00069.25 GAM22121.1 - 3.9e-80 269.0 0.0 4.4e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22121.1 - 1e-33 116.7 0.0 1.5e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM22121.1 - 0.00031 19.8 0.0 0.004 16.2 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM22121.1 - 0.0021 17.4 0.0 0.016 14.5 0.0 2.1 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 GAM22121.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAM22121.1 - 0.044 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAM22121.1 - 0.2 10.7 0.0 0.49 9.4 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Myb_DNA-binding PF00249.31 GAM22125.1 - 2.2e-44 149.4 11.8 3.6e-15 55.9 2.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM22125.1 - 2.1e-30 104.7 11.5 5e-17 61.9 1.1 4.0 3 1 1 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.8 GAM22125.1 - 2.5e-05 24.3 0.0 2.3 8.4 0.0 3.6 1 1 2 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 GAM22125.1 - 0.019 15.0 6.0 5.3 7.1 0.0 4.1 2 1 2 4 4 4 0 SLIDE Myb_DNA-bind_7 PF15963.5 GAM22125.1 - 0.052 13.4 3.7 0.076 12.9 1.7 2.4 2 0 0 2 2 2 0 Myb DNA-binding like Ank_4 PF13637.6 GAM22126.1 - 2.5e-44 149.1 10.4 2.1e-14 53.7 0.2 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM22126.1 - 1.8e-36 124.6 4.5 3.9e-16 59.4 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM22126.1 - 1.7e-31 104.7 0.9 1.4e-05 25.1 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 GAM22126.1 - 7.5e-28 96.2 3.7 2.5e-07 30.8 0.1 5.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM22126.1 - 2.1e-25 88.0 2.5 9.8e-06 25.8 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat FERM_f0 PF16511.5 GAM22127.1 - 0.0053 17.0 0.0 0.0065 16.7 0.0 1.3 1 1 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM PRP38 PF03371.15 GAM22128.1 - 6.6e-42 143.3 2.9 8.4e-42 143.0 2.9 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 GAM22128.1 - 0.03 14.9 28.1 0.03 14.9 28.1 3.6 1 1 3 4 4 4 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1497 PF07384.11 GAM22128.1 - 0.14 12.6 2.4 1.4 9.4 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1497) DUF155 PF02582.14 GAM22129.1 - 5.8e-41 140.5 0.1 9.4e-41 139.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 efThoc1 PF11957.8 GAM22129.1 - 0.054 12.2 0.1 0.08 11.6 0.1 1.1 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor DUF86 PF01934.17 GAM22129.1 - 0.1 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF86 PGM_PMM_I PF02878.16 GAM22130.1 - 3e-41 140.4 0.0 5.7e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 GAM22130.1 - 5.6e-22 78.3 0.0 1.3e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 GAM22130.1 - 4.5e-16 59.1 0.0 7.7e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 GAM22130.1 - 9.7e-07 28.9 0.0 3.1e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain LRAT PF04970.13 GAM22130.1 - 0.1 12.9 0.0 0.52 10.6 0.0 2.0 2 0 0 2 2 2 0 Lecithin retinol acyltransferase Guanylate_cyc PF00211.20 GAM22131.1 - 3.2e-53 180.1 0.1 4.6e-53 179.6 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Glyco_hydro_28 PF00295.17 GAM22132.1 - 9.3e-39 133.4 0.3 3.8e-36 124.8 0.1 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.6 GAM22132.1 - 5.8e-07 29.5 5.2 6e-06 26.2 1.5 2.4 2 0 0 2 2 2 2 Right handed beta helix region CLU PF13236.6 GAM22133.1 - 2.3e-55 187.8 0.0 5.5e-55 186.6 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria TPR_12 PF13424.6 GAM22133.1 - 5.6e-38 129.1 10.2 6.7e-15 55.1 0.1 4.9 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 GAM22133.1 - 4.7e-17 61.3 1.6 0.003 17.4 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM22133.1 - 3.4e-12 45.6 15.5 0.033 14.0 0.2 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAM22133.1 - 7.7e-11 41.2 13.7 0.029 14.5 0.2 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM22133.1 - 1.9e-09 36.9 5.9 0.021 14.8 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat eIF3_p135 PF12807.7 GAM22133.1 - 1.4e-07 31.7 0.7 1.4e-07 31.7 0.7 3.2 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_6 PF13174.6 GAM22133.1 - 1.8e-05 25.0 1.5 14 6.6 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM22133.1 - 4.1e-05 23.4 26.4 0.11 12.8 0.3 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM22133.1 - 0.016 15.4 3.2 0.11 12.8 0.1 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SwrA PF17423.2 GAM22133.1 - 0.028 14.4 0.4 0.11 12.5 0.4 2.0 1 0 0 1 1 1 0 Swarming motility protein TPR_3 PF07720.12 GAM22133.1 - 3.8 7.6 14.0 0.17 11.9 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat IPK PF03770.16 GAM22134.1 - 1.1e-48 165.7 0.1 1.1e-47 162.4 0.0 2.1 2 0 0 2 2 2 1 Inositol polyphosphate kinase MFS_1 PF07690.16 GAM22135.1 - 2.7e-38 131.8 34.6 1.9e-37 129.0 25.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM22135.1 - 3.7e-07 29.4 24.4 0.0016 17.4 26.2 2.9 1 1 1 2 2 2 2 Sugar (and other) transporter Kelch_5 PF13854.6 GAM22136.1 - 0.00042 20.2 0.1 0.0014 18.6 0.1 2.0 1 0 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 GAM22136.1 - 0.00096 19.4 0.2 0.00096 19.4 0.2 3.1 2 2 1 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAM22136.1 - 0.0011 18.9 0.7 0.0039 17.1 0.0 2.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 GAM22136.1 - 0.0012 19.1 0.2 0.0085 16.4 0.1 2.6 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM22136.1 - 0.0026 17.3 0.4 0.008 15.7 0.4 1.9 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 GAM22136.1 - 0.0028 17.6 0.6 0.013 15.5 0.1 2.4 2 0 0 2 2 2 1 Galactose oxidase, central domain MutL_C PF08676.11 GAM22137.1 - 3.5e-27 95.0 0.0 7e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 GAM22137.1 - 1.3e-22 79.7 0.0 3.4e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAM22137.1 - 1.9e-11 43.9 0.0 4.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAM22137.1 - 5.5e-05 23.6 0.0 0.00034 21.1 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIID-31kDa PF02291.15 GAM22138.1 - 5e-45 152.5 0.0 1.3e-44 151.1 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAM22138.1 - 7.4e-06 25.9 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 GAM22138.1 - 0.00012 22.4 0.0 0.00038 20.8 0.0 1.9 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAM22138.1 - 0.0043 17.2 0.3 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold TFIID_30kDa PF03540.13 GAM22138.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Histone PF00125.24 GAM22138.1 - 0.013 15.9 2.0 0.013 15.9 2.0 2.9 1 1 1 2 2 2 0 Core histone H2A/H2B/H3/H4 Macoilin PF09726.9 GAM22138.1 - 2.5 6.6 19.3 2.8 6.4 19.3 1.1 1 0 0 1 1 1 0 Macoilin family LAP1C PF05609.12 GAM22138.1 - 3.3 6.7 20.1 4 6.4 20.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cytochrom_B561 PF03188.16 GAM22139.1 - 4.3e-11 43.1 15.2 4.3e-11 43.1 15.2 1.4 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 GAM22139.1 - 1.2e-09 38.5 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 DOMON domain DUF4079 PF13301.6 GAM22139.1 - 0.64 10.2 12.1 0.27 11.4 6.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) bZIP_1 PF00170.21 GAM22140.1 - 5.4e-11 42.4 12.8 1e-09 38.3 7.2 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 GAM22140.1 - 0.00068 19.7 7.9 0.00068 19.7 7.9 2.3 2 0 0 2 2 2 1 Basic region leucine zipper SHE3 PF17078.5 GAM22140.1 - 0.013 15.2 5.5 0.038 13.7 5.5 1.7 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 GAM22140.1 - 0.029 14.9 1.8 0.029 14.9 1.8 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor RhlB PF12300.8 GAM22140.1 - 0.049 13.8 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Jnk-SapK_ap_N PF09744.9 GAM22140.1 - 0.28 11.4 9.4 0.58 10.4 9.4 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.19 GAM22140.1 - 0.95 7.3 3.7 1.6 6.6 3.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Beach PF02138.18 GAM22142.1 - 2.9e-121 404.1 1.4 2.9e-121 404.1 1.4 2.6 3 0 0 3 3 3 1 Beige/BEACH domain DUF4704 PF15787.5 GAM22142.1 - 2e-34 119.2 3.7 2e-34 119.2 3.7 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 GAM22142.1 - 5e-16 58.6 0.8 7.9e-15 54.8 0.0 3.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 GAM22142.1 - 1.6e-07 31.6 0.0 5e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 GAM22142.1 - 4e-06 27.5 5.0 6.3e-05 23.7 0.7 4.0 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF1088 PF06469.11 GAM22142.1 - 0.0011 18.7 0.7 0.0011 18.7 0.7 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1088) Pex26 PF07163.12 GAM22142.1 - 4 6.7 17.5 0.013 14.9 2.6 3.0 3 0 0 3 3 3 0 Pex26 protein RNA_pol_Rpc4 PF05132.14 GAM22143.1 - 8.6e-23 81.4 0.0 8.6e-23 81.4 0.0 3.4 3 1 0 4 4 4 1 RNA polymerase III RPC4 Ntox28 PF15605.6 GAM22143.1 - 0.73 10.1 4.3 2.1 8.6 0.9 2.3 2 0 0 2 2 2 0 Bacterial toxin 28 DUF726 PF05277.12 GAM22144.1 - 7.4e-65 219.1 0.1 1.5e-64 218.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF726) VPS9 PF02204.18 GAM22144.1 - 2.9e-08 33.8 2.1 4.8e-08 33.1 0.4 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain NPH3 PF03000.14 GAM22144.1 - 0.016 14.9 0.9 0.053 13.2 0.6 1.9 2 0 0 2 2 2 0 NPH3 family FANCI_S2 PF14676.6 GAM22144.1 - 5.1 7.4 6.4 6.7 7.0 2.2 3.0 3 0 0 3 3 3 0 FANCI solenoid 2 TFIIF_alpha PF05793.12 GAM22144.1 - 6.6 5.2 5.4 10 4.6 5.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ank_2 PF12796.7 GAM22145.1 - 0.034 14.7 0.1 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM22145.1 - 0.074 13.7 0.1 1.2 9.8 0.0 2.4 2 1 1 3 3 3 0 Ankyrin repeats (many copies) PCO_ADO PF07847.12 GAM22148.1 - 1.8e-34 118.9 0.1 2.3e-34 118.7 0.1 1.1 1 0 0 1 1 1 1 PCO_ADO Abhydro_lipase PF04083.16 GAM22149.1 - 4.8e-21 74.1 0.0 8.4e-21 73.3 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 GAM22149.1 - 6.8e-15 55.4 0.0 1.1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM22149.1 - 0.0016 19.1 0.0 0.0019 18.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aldo_ket_red PF00248.21 GAM22150.1 - 2.1e-74 250.4 0.0 2.4e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_3 PF13302.7 GAM22151.1 - 2e-17 64.2 0.0 2.3e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM22151.1 - 0.00085 19.5 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 GAM22151.1 - 0.0034 17.1 0.0 0.0092 15.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 GAM22151.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase FR47 PF08445.10 GAM22151.1 - 0.17 11.9 0.0 0.41 10.6 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein THF_DHG_CYH PF00763.23 GAM22152.1 - 2.7e-20 72.8 0.2 8e-20 71.2 0.1 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 GAM22152.1 - 6e-16 58.2 1.0 6.9e-14 51.5 1.0 3.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DpaA_N PF16924.5 GAM22152.1 - 0.0069 16.5 0.0 0.045 13.9 0.0 2.1 2 0 0 2 2 2 1 Dipicolinate synthase subunit A N-terminal domain UDPG_MGDP_dh_N PF03721.14 GAM22152.1 - 0.018 14.6 0.1 1.8 8.1 0.0 3.1 1 1 2 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PHB_acc PF05233.13 GAM22152.1 - 1.1 9.3 4.7 0.3 11.2 0.3 2.1 2 0 0 2 2 2 0 PHB accumulation regulatory domain SRF-TF PF00319.18 GAM22153.1 - 2.4e-18 65.3 0.1 4.4e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Mak10 PF04112.13 GAM22154.1 - 0.069 12.7 0.5 0.14 11.7 0.5 1.4 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ABC_tran PF00005.27 GAM22155.1 - 8.6e-45 152.6 0.0 7.1e-21 75.2 0.0 2.6 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAM22155.1 - 3.6e-22 78.2 1.5 6.9e-21 74.1 0.8 3.0 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 GAM22155.1 - 1.8e-20 74.0 0.0 0.0001 22.2 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM22155.1 - 8.6e-09 35.1 0.1 0.038 13.4 0.0 4.5 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAM22155.1 - 6.1e-08 32.8 0.3 0.0016 18.2 0.0 3.0 3 1 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM22155.1 - 3.6e-07 30.2 0.1 0.00095 19.1 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 GAM22155.1 - 4.2e-07 30.7 6.4 0.0081 16.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 GAM22155.1 - 5.2e-07 29.3 0.0 0.0073 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 GAM22155.1 - 8.2e-06 25.8 0.0 0.03 14.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 GAM22155.1 - 2.3e-05 24.9 0.0 0.013 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 GAM22155.1 - 3.7e-05 24.1 0.0 0.047 14.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 GAM22155.1 - 9.6e-05 22.8 0.0 0.0074 16.7 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 GAM22155.1 - 0.00017 21.7 0.0 0.022 14.8 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GAM22155.1 - 0.0002 21.7 0.0 0.024 14.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 GAM22155.1 - 0.00021 21.5 0.3 0.25 11.4 0.0 3.3 2 1 1 3 3 3 1 Helicase HerA, central domain AAA_14 PF13173.6 GAM22155.1 - 0.00023 21.2 0.0 1.4 9.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 GAM22155.1 - 0.00043 20.1 0.0 1.2 8.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 GAM22155.1 - 0.00063 19.9 0.0 0.54 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAM22155.1 - 0.0017 18.7 0.0 2.2 8.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 GAM22155.1 - 0.0027 17.3 0.0 0.36 10.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 GAM22155.1 - 0.0032 16.7 0.0 0.085 12.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 GAM22155.1 - 0.0035 16.9 0.0 2 8.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 GAM22155.1 - 0.0055 16.7 0.7 0.32 11.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAM22155.1 - 0.0056 17.2 0.0 1.5 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 GAM22155.1 - 0.01 15.0 0.0 0.75 8.9 0.0 2.5 2 1 0 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.15 GAM22155.1 - 0.011 15.7 0.1 0.13 12.1 0.1 2.4 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 GAM22155.1 - 0.017 15.1 0.1 8.9 6.2 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain Roc PF08477.13 GAM22155.1 - 0.021 15.0 0.0 0.47 10.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 GAM22155.1 - 0.024 14.6 0.1 1 9.4 0.0 2.8 2 1 1 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 GAM22155.1 - 0.03 13.3 0.0 4.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 GAM22155.1 - 0.047 13.4 0.0 0.44 10.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF2813 PF11398.8 GAM22155.1 - 0.049 12.9 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) Dynamin_N PF00350.23 GAM22155.1 - 0.051 13.6 0.1 12 6.0 0.0 3.1 2 1 1 3 3 3 0 Dynamin family DUF815 PF05673.13 GAM22155.1 - 0.073 12.2 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.18 GAM22155.1 - 0.079 12.2 0.0 2.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Septin Rad60-SLD PF11976.8 GAM22155.1 - 0.09 12.6 0.4 2.5 8.0 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like AAA_17 PF13207.6 GAM22155.1 - 0.17 12.3 0.6 14 6.1 0.1 2.9 2 1 0 2 2 2 0 AAA domain DUF3584 PF12128.8 GAM22155.1 - 0.17 9.4 0.4 0.4 8.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) RVT_1 PF00078.27 GAM22156.1 - 5.1e-40 137.3 0.0 7.6e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Forkhead PF00250.18 GAM22156.1 - 0.0056 16.9 0.1 0.018 15.3 0.0 1.8 2 0 0 2 2 2 1 Forkhead domain Mucin PF01456.17 GAM22157.1 - 0.01 15.8 31.7 0.017 15.1 31.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Agenet PF05641.12 GAM22157.1 - 0.093 13.2 0.1 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 Agenet domain FSA_C PF10479.9 GAM22157.1 - 0.1 10.7 12.0 0.14 10.3 12.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 GAM22157.1 - 1.4 7.1 24.4 1.9 6.6 24.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.11 GAM22157.1 - 8 6.9 15.9 17 5.8 15.9 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Casc1_N PF15927.5 GAM22158.1 - 0.017 14.9 3.1 0.05 13.3 0.4 2.3 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus FucT_N PF18025.1 GAM22158.1 - 0.048 14.1 1.0 0.19 12.2 0.1 2.4 2 1 1 3 3 3 0 Alpha-(1,3)-fucosyltransferase FucT N-terminal domain CRIM PF16978.5 GAM22160.1 - 2.3e-12 47.2 0.2 7.7e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 GAM22160.1 - 9.2e-12 45.2 2.6 9.2e-12 45.2 2.6 2.6 3 0 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 GAM22160.1 - 1.9e-05 24.6 0.1 1.9e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 Raf-like Ras-binding domain MARVEL PF01284.23 GAM22162.1 - 0.13 12.3 3.6 0.14 12.2 3.6 1.1 1 0 0 1 1 1 0 Membrane-associating domain COBRA1 PF06209.13 GAM22162.1 - 0.14 11.0 2.2 0.17 10.7 2.2 1.1 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) PsbH PF00737.20 GAM22162.1 - 7 6.5 15.7 1.7 8.4 1.9 2.3 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Methyltransf_2 PF00891.18 GAM22163.1 - 6.7e-43 146.4 0.0 8.9e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 GAM22163.1 - 3.4e-09 36.6 0.0 7.9e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Bin3 PF06859.12 GAM22163.1 - 0.034 14.8 0.0 0.087 13.5 0.0 1.7 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) HTH_Tnp_1_2 PF13022.6 GAM22163.1 - 0.05 13.8 0.1 1 9.5 0.0 2.6 2 1 1 3 3 3 0 Helix-turn-helix of insertion element transposase Methyltransf_12 PF08242.12 GAM22163.1 - 0.074 13.8 0.0 0.21 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF937 PF06078.11 GAM22163.1 - 0.11 13.1 1.8 26 5.4 0.0 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Methyltransf_25 PF13649.6 GAM22163.1 - 0.13 13.0 0.1 1 10.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain SF-assemblin PF06705.11 GAM22163.1 - 0.14 11.4 1.0 0.32 10.3 1.0 1.5 1 0 0 1 1 1 0 SF-assemblin/beta giardin HTH_38 PF13936.6 GAM22163.1 - 0.18 11.6 0.1 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Beach PF02138.18 GAM22164.1 - 5.7e-121 403.1 1.2 7.1e-121 402.8 0.4 1.6 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.32 GAM22164.1 - 1.3e-24 86.0 14.6 2e-05 25.3 0.5 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM22164.1 - 1.1e-15 57.6 0.4 0.0045 17.3 0.0 5.8 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH PF14844.6 GAM22164.1 - 2.3e-13 50.1 1.2 2.2e-11 43.7 0.7 3.2 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH WD40_like PF17005.5 GAM22164.1 - 7.5e-13 48.5 5.8 6.7e-10 38.8 0.3 2.9 2 1 0 2 2 2 2 WD40-like domain GRAM PF02893.20 GAM22164.1 - 1.9e-08 34.2 1.0 0.00014 21.7 0.4 2.6 2 0 0 2 2 2 2 GRAM domain BBS2_Mid PF14783.6 GAM22164.1 - 0.0011 19.0 0.1 0.39 10.8 0.0 4.3 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region IQCJ-SCHIP1 PF15157.6 GAM22164.1 - 0.03 14.2 0.0 0.092 12.6 0.0 1.8 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Dynamin_N PF00350.23 GAM22165.1 - 0.0011 19.0 0.0 0.0098 16.0 0.0 2.7 2 1 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 GAM22165.1 - 0.0042 17.5 0.0 0.014 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Ints3 PF10189.9 GAM22165.1 - 0.0096 15.2 0.0 0.037 13.3 0.1 1.9 2 0 0 2 2 2 1 Integrator complex subunit 3 MMR_HSR1 PF01926.23 GAM22165.1 - 0.13 12.3 0.0 0.56 10.3 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase zf-C2H2_2 PF12756.7 GAM22166.1 - 4.9e-39 132.8 14.9 5.3e-21 74.9 2.0 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAM22166.1 - 1.4e-07 31.8 21.7 0.11 13.4 1.0 6.0 6 0 0 6 6 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM22166.1 - 5.3e-05 23.4 16.7 0.00025 21.2 5.2 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 GAM22166.1 - 0.00035 20.3 8.1 0.085 12.6 0.8 3.2 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-met PF12874.7 GAM22166.1 - 0.00051 20.3 4.1 0.00051 20.3 4.1 2.9 3 0 0 3 3 2 1 Zinc-finger of C2H2 type DUF4187 PF13821.6 GAM22166.1 - 0.0043 16.8 6.4 0.71 9.7 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4187) zf-C2H2 PF00096.26 GAM22166.1 - 0.0052 17.2 20.7 0.18 12.3 2.3 5.6 5 0 0 5 5 5 2 Zinc finger, C2H2 type PAS_4 PF08448.10 GAM22166.1 - 0.029 14.6 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 PAS fold zf-BED PF02892.15 GAM22166.1 - 0.082 12.9 6.2 9.3 6.4 1.4 3.8 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_9 PF16293.5 GAM22166.1 - 0.086 12.7 0.1 0.086 12.7 0.1 3.6 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 GAM22166.1 - 0.12 12.4 11.8 0.059 13.4 2.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 GAM22166.1 - 0.27 11.6 0.2 0.27 11.6 0.2 5.3 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding BIR PF00653.21 GAM22166.1 - 0.27 11.9 15.0 2.5 8.8 1.6 4.5 5 0 0 5 5 5 0 Inhibitor of Apoptosis domain Myb_DNA-binding PF00249.31 GAM22168.1 - 0.0027 17.9 0.2 0.0059 16.8 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain LLC1 PF14945.6 GAM22168.1 - 1.4 9.5 4.6 3.6 8.2 1.1 2.5 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Methyltransf_2 PF00891.18 GAM22170.1 - 6.9e-40 136.6 0.0 1.2e-39 135.8 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 GAM22170.1 - 2.2e-07 30.8 0.1 6.8e-07 29.2 0.1 1.8 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_23 PF13489.6 GAM22170.1 - 0.00066 19.5 0.0 0.0029 17.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM22170.1 - 0.083 13.6 0.0 0.34 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain HTH_20 PF12840.7 GAM22170.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Ad_Cy_reg PF16701.5 GAM22170.1 - 0.12 12.1 0.2 1.3 8.8 0.2 2.1 2 0 0 2 2 2 0 Adenylate cyclase regulatory domain Macro PF01661.21 GAM22171.1 - 1.5e-32 112.1 0.1 3.9e-32 110.8 0.1 1.7 1 0 0 1 1 1 1 Macro domain Atrophin-1 PF03154.15 GAM22171.1 - 0.16 10.2 8.5 0.27 9.5 8.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family FSA_C PF10479.9 GAM22171.1 - 3.6 5.6 11.6 5.5 5.0 11.6 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Amidinotransf PF02274.17 GAM22172.1 - 4.5e-16 58.9 0.0 1.6e-13 50.5 0.0 2.3 1 1 0 1 1 1 1 Amidinotransferase SNF2_N PF00176.23 GAM22173.1 - 1.4e-58 198.3 4.2 1.4e-58 198.3 4.2 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad60-SLD PF11976.8 GAM22173.1 - 7e-26 89.9 5.7 2.2e-05 24.2 0.0 5.9 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Helicase_C PF00271.31 GAM22173.1 - 1.1e-18 67.6 0.0 1.1e-18 67.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 GAM22173.1 - 3.1e-07 30.2 0.1 1.8e-06 27.7 0.1 2.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SLIDE PF09111.10 GAM22173.1 - 1.1e-05 25.4 8.8 0.0024 17.9 0.0 5.2 4 0 0 4 4 4 2 SLIDE ubiquitin PF00240.23 GAM22173.1 - 1.4e-05 24.7 0.3 0.064 13.0 0.0 5.1 3 1 1 4 4 4 1 Ubiquitin family CHDCT2 PF08074.11 GAM22173.1 - 0.049 13.8 0.0 0.049 13.8 0.0 3.8 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain RRM_1 PF00076.22 GAM22174.1 - 4.9e-38 128.8 0.2 3.1e-13 49.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM22174.1 - 6.2e-06 25.8 0.0 0.012 15.2 0.1 2.5 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM22174.1 - 0.00011 22.1 0.0 0.0045 17.0 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif BRAP2 PF07576.12 GAM22174.1 - 0.0011 19.2 0.1 0.0067 16.6 0.0 2.1 2 0 0 2 2 2 1 BRCA1-associated protein 2 RRM_7 PF16367.5 GAM22174.1 - 0.0028 17.7 0.1 1.9 8.7 0.0 3.1 3 1 0 3 3 3 2 RNA recognition motif PHM7_cyt PF14703.6 GAM22174.1 - 0.0046 17.2 0.4 3.5 7.8 0.0 3.9 2 1 1 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter C1_1 PF00130.22 GAM22175.1 - 1.7e-12 47.0 23.5 1.1e-06 28.4 5.7 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) BLOC1_2 PF10046.9 GAM22175.1 - 0.0074 16.6 1.6 0.037 14.3 0.2 2.9 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 FdtA PF05523.11 GAM22175.1 - 0.081 12.6 0.7 0.18 11.5 0.7 1.5 1 0 0 1 1 1 0 WxcM-like, C-terminal C1_2 PF03107.16 GAM22175.1 - 2.4 8.6 14.6 0.44 10.9 3.9 2.6 2 0 0 2 2 2 0 C1 domain PHD PF00628.29 GAM22175.1 - 4.8 7.1 16.1 3.6 7.6 4.6 2.5 2 0 0 2 2 2 0 PHD-finger Lipase_3 PF01764.25 GAM22176.1 - 5.7e-36 123.5 0.0 8.8e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GAM22176.1 - 0.0028 17.2 0.0 0.0059 16.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 GAM22176.1 - 0.0043 16.8 0.0 0.0057 16.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAM22176.1 - 0.025 15.2 0.0 0.034 14.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 GAM22176.1 - 0.05 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family FlhC PF05280.11 GAM22176.1 - 0.23 11.2 1.0 11 5.7 0.0 2.3 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) Myb_DNA-bind_6 PF13921.6 GAM22177.1 - 0.00012 22.3 0.0 0.00033 20.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAM22177.1 - 0.00046 20.3 0.1 0.0013 18.9 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 GAM22177.1 - 0.0073 16.4 0.0 0.034 14.2 0.0 2.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAM22177.1 - 0.026 14.7 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 FNIP PF05725.12 GAM22179.1 - 3.1e-54 180.9 10.7 1.2e-15 57.4 0.0 8.1 6 3 3 9 9 9 7 FNIP Repeat DUF1769 PF08588.10 GAM22179.1 - 0.0014 18.8 0.8 8.5 6.7 0.0 4.5 3 1 3 6 6 6 2 Protein of unknown function (DUF1769) IBN_N PF03810.19 GAM22180.1 - 2.9e-11 43.1 3.9 5.4e-11 42.3 0.3 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 GAM22180.1 - 1e-08 34.4 3.2 5.9e-07 28.6 0.2 3.0 2 1 0 3 3 3 2 Cse1 HEAT PF02985.22 GAM22180.1 - 2.3e-05 24.2 0.1 0.13 12.6 0.0 3.8 2 0 0 2 2 2 2 HEAT repeat Xpo1 PF08389.12 GAM22180.1 - 0.0015 18.6 0.1 0.016 15.2 0.0 2.9 2 1 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 GAM22180.1 - 0.015 15.7 0.3 0.13 12.7 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats DUF3295 PF11702.8 GAM22180.1 - 3.3 7.0 4.5 5.3 6.3 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) HEAT_EZ PF13513.6 GAM22180.1 - 6.5 7.4 10.8 13 6.4 0.0 5.1 7 0 0 7 7 7 0 HEAT-like repeat FNIP PF05725.12 GAM22185.1 - 2.5e-23 81.9 5.5 4.8e-07 29.8 0.1 5.6 2 2 1 5 5 5 5 FNIP Repeat Exo_endo_phos PF03372.23 GAM22186.1 - 0.014 14.9 0.6 0.021 14.4 0.5 1.4 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAM22186.1 - 0.039 13.8 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Zip PF02535.22 GAM22187.1 - 0.042 13.1 0.5 0.048 12.9 0.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ACP53EA PF06313.11 GAM22187.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Drosophila ACP53EA protein SDA1 PF05285.12 GAM22188.1 - 0.00048 19.7 19.7 0.00065 19.2 19.7 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GAM22188.1 - 0.0021 16.4 19.1 0.0021 16.4 19.1 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 GAM22188.1 - 0.038 13.4 20.7 0.05 12.9 20.7 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_B_2 PF03175.13 GAM22189.1 - 2e-05 23.7 0.3 3e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral SBP_bac_1 PF01547.25 GAM22189.1 - 0.053 13.5 0.1 0.08 12.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein TFA2_Winged_2 PF18121.1 GAM22189.1 - 0.056 13.1 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 DUF1281 PF06924.11 GAM22189.1 - 0.086 12.4 0.0 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) Alg6_Alg8 PF03155.15 GAM22191.1 - 9.4e-139 463.5 20.0 1.1e-138 463.3 20.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ThiF PF00899.21 GAM22192.1 - 1.8e-66 223.9 0.1 2.9e-66 223.3 0.1 1.3 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 GAM22192.1 - 3.1e-21 75.8 1.9 1.3e-20 73.7 0.9 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 GAM22192.1 - 1.1e-08 35.4 2.0 1.1e-05 25.5 0.1 2.7 3 0 0 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 GAM22192.1 - 5.7e-05 23.5 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 GAM22192.1 - 0.00021 21.4 0.1 0.00051 20.1 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 GAM22192.1 - 0.031 14.6 0.1 0.076 13.3 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 GAM22192.1 - 0.031 13.4 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UBA2_C PF16195.5 GAM22192.1 - 0.046 14.4 2.9 0.14 12.9 2.9 1.8 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Ldh_1_N PF00056.23 GAM22192.1 - 0.052 13.7 0.3 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAM22192.1 - 0.055 13.7 0.2 0.24 11.7 0.2 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 GAM22192.1 - 0.073 13.6 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rad50_zn_hook PF04423.14 GAM22192.1 - 0.081 12.8 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif POT1 PF02765.17 GAM22193.1 - 6.7e-10 39.0 0.3 1.6e-09 37.8 0.1 1.7 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Rep_fac-A_C PF08646.10 GAM22193.1 - 2.4e-05 24.1 0.2 7.2e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.25 GAM22193.1 - 0.085 12.9 0.0 5.2 7.1 0.0 3.1 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Mito_fiss_reg PF05308.11 GAM22194.1 - 0.00088 19.4 9.5 0.00088 19.4 9.5 3.2 2 1 1 3 3 3 1 Mitochondrial fission regulator DUF4611 PF15387.6 GAM22194.1 - 0.16 12.2 0.6 12 6.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) KIAA1430 PF13879.6 GAM22194.1 - 0.66 10.8 4.9 40 5.0 0.0 2.9 3 0 0 3 3 3 0 KIAA1430 homologue Methyltransf_11 PF08241.12 GAM22196.1 - 1.8e-22 79.8 0.0 3.5e-22 78.9 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM22196.1 - 1.3e-21 77.0 0.0 1.4e-21 76.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM22196.1 - 1.3e-20 73.8 0.0 2.2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM22196.1 - 2.6e-15 56.4 0.0 4.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAM22196.1 - 7.6e-12 45.8 0.0 1.2e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM22196.1 - 2.5e-09 37.2 0.0 3.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAM22196.1 - 5.5e-07 29.4 0.0 8.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 GAM22196.1 - 3.5e-05 23.7 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 GAM22196.1 - 0.00023 20.7 0.0 0.00062 19.3 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Pox_MCEL PF03291.16 GAM22196.1 - 0.00026 20.2 0.0 0.0006 19.0 0.0 1.6 2 0 0 2 2 2 1 mRNA capping enzyme Methyltransf_32 PF13679.6 GAM22196.1 - 0.003 17.5 0.0 0.0055 16.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAM22196.1 - 0.057 12.7 0.1 0.13 11.5 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase RRM_1 PF00076.22 GAM22197.1 - 3e-18 65.4 0.0 4.5e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM22197.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Amino_oxidase PF01593.24 GAM22198.1 - 7.9e-47 160.6 0.0 1.3e-44 153.3 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM22198.1 - 1.1e-08 35.2 0.1 2.6e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM22198.1 - 3.2e-05 22.8 0.0 6.5e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAM22198.1 - 5.1e-05 22.6 0.1 0.0012 18.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM22198.1 - 0.0002 21.1 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM22198.1 - 0.00031 20.1 0.1 0.00066 19.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAM22198.1 - 0.0018 17.6 0.2 0.0081 15.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM22198.1 - 0.0021 18.6 0.1 1.5 9.4 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM22198.1 - 0.0021 17.2 0.2 0.0038 16.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAM22198.1 - 0.0031 16.8 0.3 0.0061 15.8 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAM22198.1 - 0.0039 16.6 0.0 0.045 13.1 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM22198.1 - 0.041 12.9 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 GAM22198.1 - 0.063 12.4 0.1 0.14 11.2 0.1 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A Pkinase PF00069.25 GAM22199.1 - 3.1e-68 230.0 0.4 3.8e-68 229.7 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22199.1 - 2.1e-52 178.0 0.2 2.7e-52 177.6 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM22199.1 - 1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAM22199.1 - 7.2e-05 21.9 1.4 0.00031 19.8 1.4 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM22199.1 - 0.0018 17.2 0.1 0.0034 16.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 GAM22199.1 - 0.0082 15.8 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAM22199.1 - 0.0085 16.0 0.0 0.72 9.7 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GAM22199.1 - 0.025 13.9 0.6 0.042 13.2 0.6 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mcm10 PF09332.11 GAM22200.1 - 0.64 9.4 13.4 1.8 7.9 13.4 1.8 1 0 0 1 1 1 0 Mcm10 replication factor FAD_binding_4 PF01565.23 GAM22201.1 - 1e-29 103.1 0.0 1.6e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAM22201.1 - 2.8e-17 62.6 4.1 7.3e-17 61.2 4.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like Ank_2 PF12796.7 GAM22202.1 - 1.1e-39 134.8 7.8 2.6e-12 47.2 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM22202.1 - 2.3e-33 110.4 4.7 2.3e-05 24.4 0.1 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 GAM22202.1 - 2.6e-31 107.6 2.0 2.2e-11 44.0 0.0 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM22202.1 - 3.2e-30 103.2 8.4 4.1e-06 27.0 0.2 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 GAM22202.1 - 1.2e-25 89.2 4.6 6.5e-09 35.9 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) TPR_2 PF07719.17 GAM22202.1 - 3.9e-07 29.7 8.2 0.002 18.1 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM22202.1 - 0.00027 20.6 9.3 0.011 15.5 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM22202.1 - 0.0013 19.0 1.7 0.023 15.0 0.7 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Gas_vesicle_C PF01304.17 GAM22202.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain TPR_16 PF13432.6 GAM22202.1 - 0.13 13.0 4.4 0.75 10.5 1.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM22202.1 - 0.13 12.5 7.4 9.4 6.7 0.1 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat DXPR_C PF13288.6 GAM22202.1 - 0.14 12.4 0.9 2.7 8.3 0.4 2.6 2 0 0 2 2 2 0 DXP reductoisomerase C-terminal domain VWA_3_C PF18571.1 GAM22202.1 - 0.34 10.8 1.6 16 5.5 0.1 3.9 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain C2 PF00168.30 GAM22204.1 - 0.00012 22.3 0.0 0.00024 21.3 0.0 1.4 1 1 0 1 1 1 1 C2 domain GNT-I PF03071.15 GAM22205.1 - 1.9e-05 23.6 0.1 2.8e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 GNT-I family Glyco_transf_18 PF15024.6 GAM22205.1 - 0.11 11.1 0.3 0.15 10.6 0.3 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 CH PF00307.31 GAM22206.1 - 6.4e-50 167.9 6.0 2e-25 89.1 0.0 4.2 4 0 0 4 4 4 3 Calponin homology (CH) domain Spectrin PF00435.21 GAM22206.1 - 6.3e-32 110.2 27.7 1e-11 45.2 0.6 4.6 4 0 0 4 4 4 4 Spectrin repeat CAMSAP_CH PF11971.8 GAM22206.1 - 2.5e-09 36.8 1.3 1.7e-06 27.7 0.1 3.4 3 0 0 3 3 3 2 CAMSAP CH domain CH_2 PF06294.11 GAM22206.1 - 3.4e-07 30.3 0.1 0.17 12.0 0.0 4.3 4 0 0 4 4 4 2 CH-like domain in sperm protein EFhand_Ca_insen PF08726.10 GAM22206.1 - 4.2e-07 30.0 0.0 1.9e-06 27.9 0.0 2.3 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_7 PF13499.6 GAM22206.1 - 2.1e-05 24.9 0.1 0.0002 21.7 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 GAM22206.1 - 0.0053 16.2 0.0 0.18 11.4 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GAM22206.1 - 0.007 16.2 0.1 0.057 13.4 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain MCPsignal PF00015.21 GAM22206.1 - 0.44 10.3 8.4 0.62 9.8 0.0 3.9 4 0 0 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LSM PF01423.22 GAM22208.1 - 2.9e-16 58.9 0.5 3.9e-16 58.5 0.5 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM22208.1 - 7.4e-05 22.8 0.0 9.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Feld-I_B PF09252.10 GAM22208.1 - 0.17 11.9 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Allergen Fel d I-B chain CLU PF13236.6 GAM22209.1 - 1.1e-57 195.4 0.0 2.2e-57 194.4 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAM22209.1 - 3.6e-08 33.7 12.5 4.2e-08 33.4 0.1 3.7 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 DUF908 PF06012.12 GAM22209.1 - 4.4 6.6 15.7 11 5.3 15.7 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) LRR_6 PF13516.6 GAM22209.1 - 5.4 7.3 11.8 12 6.3 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeat DUF1349 PF07081.11 GAM22210.1 - 1.3e-57 194.4 0.5 1.5e-57 194.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GH43_C2 PF17851.1 GAM22210.1 - 3.4e-06 26.9 0.0 4.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Peptidase_M48_N PF16491.5 GAM22211.1 - 5.2e-54 182.9 14.6 5.2e-54 182.9 14.6 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 GAM22211.1 - 5.2e-42 143.8 0.0 1.1e-41 142.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 GAM22211.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_M56 PF05569.11 GAM22211.1 - 0.8 8.8 7.2 0.24 10.5 0.2 2.5 3 0 0 3 3 3 0 BlaR1 peptidase M56 Ras PF00071.22 GAM22212.1 - 1.8e-52 177.2 0.3 2e-52 177.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM22212.1 - 2.1e-18 66.7 0.1 4.2e-18 65.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM22212.1 - 4.3e-10 39.3 0.3 5e-10 39.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAM22212.1 - 0.0095 15.9 0.1 0.25 11.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAM22212.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 GAM22212.1 - 0.036 13.2 1.9 4 6.5 0.1 2.3 2 1 0 2 2 2 0 G-protein alpha subunit DUF3568 PF12092.8 GAM22212.1 - 0.053 13.6 0.4 0.07 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) RRM_1 PF00076.22 GAM22213.1 - 8.6e-69 227.3 2.1 1.5e-18 66.3 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAM22213.1 - 1.3e-11 44.5 0.1 3.2e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 GAM22213.1 - 1.1e-06 28.3 0.3 0.0061 16.2 0.1 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAM22213.1 - 3.2e-05 23.9 4.3 0.027 14.5 0.1 3.9 3 1 1 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.6 GAM22213.1 - 0.0038 17.2 1.5 16 5.6 0.1 3.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 GAM22213.1 - 0.0045 16.8 0.1 0.019 14.8 0.1 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF4523 PF15023.6 GAM22213.1 - 0.0094 15.8 0.0 2.9 7.7 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) NID PF07292.13 GAM22213.1 - 0.11 13.2 2.4 0.28 11.8 0.2 2.6 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) SET_assoc PF11767.8 GAM22213.1 - 0.15 11.7 0.0 30 4.3 0.0 3.2 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Menin PF05053.13 GAM22213.1 - 8.3 4.6 8.4 16 3.7 8.4 1.4 1 0 0 1 1 1 0 Menin Glycos_transf_4 PF00953.21 GAM22214.1 - 3.5e-36 124.6 13.9 3.5e-36 124.6 13.9 2.3 3 1 0 3 3 3 1 Glycosyl transferase family 4 Myosin_head PF00063.21 GAM22215.1 - 3e-268 891.6 0.1 3.8e-268 891.3 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAM22215.1 - 4.1e-42 144.0 2.3 7.5e-42 143.1 2.3 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 GAM22215.1 - 9.1e-17 60.4 0.1 1.8e-16 59.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM22215.1 - 9.5e-17 60.6 0.1 2e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM22215.1 - 6.8e-13 48.1 0.1 1.5e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 GAM22215.1 - 0.0041 17.5 0.0 0.0083 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM22215.1 - 0.0085 16.4 0.0 0.062 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain IQ PF00612.27 GAM22215.1 - 0.0087 15.8 0.1 0.025 14.3 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF2075 PF09848.9 GAM22215.1 - 0.026 13.8 0.1 0.057 12.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 GAM22215.1 - 0.052 12.7 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 GAM22215.1 - 0.056 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.9 GAM22215.1 - 0.062 12.2 0.1 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Comm PF15957.5 GAM22215.1 - 0.091 13.1 0.3 5.6 7.3 0.0 2.9 2 1 0 3 3 3 0 Commissureless RsgA_GTPase PF03193.16 GAM22215.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 GAM22215.1 - 0.18 12.2 0.3 0.57 10.6 0.1 2.0 2 0 0 2 2 1 0 RNA helicase AAA_19 PF13245.6 GAM22215.1 - 0.2 12.0 0.6 1 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAM22215.1 - 0.85 10.1 3.2 0.94 10.0 0.2 2.6 2 2 0 2 2 2 0 ABC transporter DZR PF12773.7 GAM22216.1 - 0.0015 18.6 9.4 0.018 15.0 9.4 2.3 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 GAM22216.1 - 0.014 15.1 8.3 0.047 13.4 3.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 GAM22216.1 - 0.017 14.5 9.6 0.21 11.0 3.8 2.7 2 1 0 2 2 2 0 zinc-ribbon domain DUF4451 PF14616.6 GAM22216.1 - 0.023 14.9 3.4 0.03 14.5 3.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) C1_1 PF00130.22 GAM22216.1 - 0.028 14.3 4.9 2.4 8.1 0.3 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.10 GAM22216.1 - 1.8 8.4 7.2 19 5.1 0.1 3.6 4 0 0 4 4 4 0 A2L zinc ribbon domain zinc_ribbon_15 PF17032.5 GAM22216.1 - 2.4 9.0 7.9 18 6.1 7.9 2.1 1 1 0 1 1 1 0 zinc-ribbon family zf-C2H2_4 PF13894.6 GAM22216.1 - 7.7 7.7 8.9 21 6.3 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 GAM22216.1 - 7.8 6.8 10.3 18 5.7 0.1 3.3 2 1 1 3 3 3 0 zinc-ribbon RabGAP-TBC PF00566.18 GAM22217.1 - 1.2e-47 162.3 6.5 1.2e-47 162.3 6.5 3.7 4 1 0 4 4 4 1 Rab-GTPase-TBC domain FapA PF03961.13 GAM22217.1 - 0.22 10.1 6.9 0.068 11.8 3.3 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF948 PF06103.11 GAM22217.1 - 0.32 11.3 1.2 1.1 9.5 1.2 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PRANC PF09372.10 GAM22217.1 - 2.5 8.5 7.6 1.4 9.3 1.7 3.1 2 1 0 3 3 3 0 PRANC domain LOH1CR12 PF10158.9 GAM22217.1 - 9 6.3 15.4 0.11 12.5 5.9 2.7 2 1 1 3 3 3 0 Tumour suppressor protein DegS PF05384.11 GAM22217.1 - 9.9 5.6 12.0 0.033 13.7 1.5 2.3 3 0 0 3 3 3 0 Sensor protein DegS FYVE PF01363.21 GAM22218.1 - 0.00029 20.9 7.0 0.00049 20.2 4.9 2.2 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 GAM22218.1 - 0.012 15.5 2.2 0.012 15.5 2.2 2.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NAPRTase_N PF17767.1 GAM22218.1 - 0.016 15.6 0.4 0.035 14.5 0.4 1.5 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain YxiJ PF14176.6 GAM22218.1 - 0.066 13.7 1.2 0.26 11.8 1.1 2.1 1 1 1 2 2 2 0 YxiJ-like protein Syntaxin_2 PF14523.6 GAM22218.1 - 0.22 11.9 2.5 0.24 11.8 0.4 2.0 2 0 0 2 2 2 0 Syntaxin-like protein DZR PF12773.7 GAM22218.1 - 0.28 11.2 10.1 3.1 7.9 5.7 2.8 2 1 1 3 3 3 0 Double zinc ribbon FYVE_2 PF02318.16 GAM22218.1 - 1.2 9.4 14.1 0.35 11.1 7.1 2.7 2 2 0 2 2 2 0 FYVE-type zinc finger zf-dskA_traR PF01258.17 GAM22218.1 - 5.6 7.0 6.5 6.6 6.8 0.1 2.9 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger UQ_con PF00179.26 GAM22219.1 - 3.2e-27 94.9 0.0 6.5e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 GAM22219.1 - 0.0071 16.2 0.2 0.016 15.1 0.2 1.5 1 0 0 1 1 1 1 UEV domain Borrelia_orfA PF02414.15 GAM22219.1 - 3.1 7.4 13.5 0.4 10.3 8.6 1.9 2 0 0 2 2 2 0 Borrelia ORF-A Tho2 PF11262.8 GAM22222.1 - 8.3e-82 274.8 6.1 8.3e-82 274.8 6.1 5.4 5 1 1 6 6 6 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 GAM22222.1 - 2.6e-55 188.2 12.9 2.5e-37 128.9 5.9 6.7 3 2 3 6 6 6 3 THO complex subunit 2 N-terminus Thoc2 PF11732.8 GAM22222.1 - 7.9e-23 80.3 0.0 2.8e-22 78.5 0.0 2.1 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Cyclin PF08613.11 GAM22223.1 - 1.1e-34 120.1 0.2 1.1e-34 120.1 0.2 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAM22223.1 - 1.8e-09 37.4 0.0 2.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Patched PF02460.18 GAM22224.1 - 1.9 6.5 6.0 1.5 6.8 5.0 1.3 1 1 0 1 1 1 0 Patched family DUF2975 PF11188.8 GAM22224.1 - 3.7 7.4 8.6 0.26 11.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Glycos_transf_1 PF00534.20 GAM22225.1 - 5.2e-37 127.0 0.0 8.1e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAM22225.1 - 4.6e-16 59.3 0.1 8.5e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAM22225.1 - 7.2e-15 55.6 0.0 1.2e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAM22225.1 - 2.8e-09 37.6 0.0 4.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 GAM22225.1 - 3.8e-05 24.0 0.0 7.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 LRR_4 PF12799.7 GAM22226.1 - 4.1e-10 39.7 14.7 8.2e-08 32.4 2.0 3.8 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAM22226.1 - 2.4e-09 36.9 0.5 5.6e-09 35.7 0.5 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 GAM22226.1 - 2e-08 33.9 7.4 8.7e-05 22.2 0.9 3.5 3 1 0 3 3 3 2 Leucine rich repeat CG-1 PF03859.16 GAM22226.1 - 0.036 13.8 0.2 0.036 13.8 0.2 2.3 2 0 0 2 2 2 0 CG-1 domain Mpv17_PMP22 PF04117.12 GAM22227.1 - 5.2e-20 71.4 0.2 9.5e-20 70.6 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family PetN PF03742.14 GAM22227.1 - 0.022 14.6 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 PetN CybS PF05328.12 GAM22227.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit TMEM154 PF15102.6 GAM22228.1 - 4.3 7.3 13.7 14 5.6 13.7 1.9 1 0 0 1 1 1 0 TMEM154 protein family DUF3467 PF11950.8 GAM22231.1 - 0.14 12.3 0.5 1.5 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) DDE_3 PF13358.6 GAM22232.1 - 1.3e-09 38.0 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TTD PF12148.8 GAM22233.1 - 0.004 17.0 0.0 0.004 17.0 0.0 2.7 2 1 0 2 2 2 1 Tandem tudor domain within UHRF1 BetaGal_dom4_5 PF13364.6 GAM22233.1 - 0.034 14.7 0.0 0.08 13.5 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Hormone_recep PF00104.30 GAM22233.1 - 0.034 13.7 0.1 0.034 13.7 0.1 1.8 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor Agenet PF05641.12 GAM22233.1 - 0.062 13.8 2.2 0.069 13.6 0.0 2.3 2 0 0 2 2 2 0 Agenet domain Abi_C PF14355.6 GAM22233.1 - 0.13 12.4 0.0 0.53 10.4 0.0 2.2 1 0 0 1 1 1 0 Abortive infection C-terminus BUD22 PF09073.10 GAM22233.1 - 0.25 10.6 17.8 0.33 10.2 17.8 1.2 1 0 0 1 1 1 0 BUD22 PQ-loop PF04193.14 GAM22236.1 - 5.4e-20 70.9 13.4 2.4e-16 59.2 0.3 3.0 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 GAM22236.1 - 1.2e-05 26.2 11.2 1.2e-05 26.2 8.4 2.0 1 1 1 2 2 2 2 ER lumen protein retaining receptor Gelsolin PF00626.22 GAM22236.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Gelsolin repeat CTP_transf_1 PF01148.20 GAM22236.1 - 0.3 10.8 10.7 0.098 12.4 7.4 1.7 1 1 1 2 2 2 0 Cytidylyltransferase family BolA PF01722.18 GAM22237.1 - 7.9e-15 54.9 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Imm9 PF15587.6 GAM22237.1 - 0.0097 15.6 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Immunity protein 9 DUF3124 PF11322.8 GAM22237.1 - 0.056 13.6 0.0 0.079 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) zf-C2H2_2 PF12756.7 GAM22238.1 - 3e-34 117.4 13.0 3.3e-28 98.0 2.7 3.0 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GAM22238.1 - 1.3e-10 41.3 16.4 7.1e-08 32.5 2.5 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM22238.1 - 3.3e-09 36.8 3.8 1.4e-08 34.8 0.8 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAM22238.1 - 0.015 16.1 16.5 0.21 12.5 0.2 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAM22238.1 - 0.053 13.5 1.9 0.15 12.1 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4674 PF15719.5 GAM22238.1 - 0.055 13.5 4.6 0.12 12.4 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) zf-LYAR PF08790.11 GAM22238.1 - 0.08 12.9 4.5 0.52 10.3 0.3 2.9 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Actin_micro PF17003.5 GAM22238.1 - 0.49 9.5 5.7 0.31 10.2 2.2 2.4 1 1 1 2 2 2 0 Putative actin-like family zf-nanos PF05741.13 GAM22238.1 - 0.82 9.9 7.0 12 6.2 0.3 3.5 3 0 0 3 3 3 0 Nanos RNA binding domain Ribosomal_S8e PF01201.22 GAM22239.1 - 6.3e-49 165.7 2.1 1.3e-48 164.7 2.1 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Alpha-amylase PF00128.24 GAM22240.1 - 8e-17 61.8 0.0 4.8e-16 59.2 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 GAM22240.1 - 0.018 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain LBP_C PF17386.2 GAM22240.1 - 0.034 14.0 0.0 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase C-terminal domain Malt_amylase_C PF16657.5 GAM22240.1 - 0.11 12.6 0.0 0.66 10.1 0.0 2.3 3 0 0 3 3 3 0 Maltogenic Amylase, C-terminal domain Acyltransferase PF01553.21 GAM22241.1 - 1.7e-22 79.5 0.0 2.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 GAM22241.1 - 2.7e-15 56.2 0.2 9.4e-15 54.5 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase C-terminus Cytochrom_C_2 PF01322.20 GAM22241.1 - 0.032 15.1 0.0 0.16 12.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome C' ATP-synt_ab PF00006.25 GAM22242.1 - 2.1e-61 207.3 0.0 3.4e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAM22242.1 - 1.2e-17 64.1 1.7 4.1e-16 59.3 1.7 2.5 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 GAM22242.1 - 0.0083 15.3 1.0 0.018 14.2 0.2 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 GAM22242.1 - 0.031 14.7 0.6 0.44 11.0 0.0 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM22242.1 - 0.032 14.6 0.1 0.1 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 GAM22242.1 - 0.033 14.1 0.5 0.083 12.8 0.2 1.8 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 GAM22242.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 GAM22242.1 - 0.05 14.0 0.9 0.45 10.9 0.0 3.0 5 0 0 5 5 3 0 RNA helicase VitK2_biosynth PF02621.14 GAM22242.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Menaquinone biosynthesis ABC_tran PF00005.27 GAM22242.1 - 0.13 12.8 2.6 0.74 10.3 0.2 2.8 3 0 0 3 3 3 0 ABC transporter AAA_19 PF13245.6 GAM22242.1 - 0.17 12.2 0.6 0.55 10.5 0.2 2.0 2 0 0 2 2 2 0 AAA domain KRE1 PF17056.5 GAM22242.1 - 0.21 11.3 2.7 5.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Killer toxin-resistance protein 1 ATPase PF06745.13 GAM22242.1 - 0.38 10.1 4.8 0.17 11.2 1.0 2.2 2 0 0 2 2 2 0 KaiC Arfaptin PF06456.13 GAM22242.1 - 5.4 6.5 7.6 2.7 7.5 1.5 2.7 3 0 0 3 3 3 0 Arfaptin-like domain Stm1_N PF09598.10 GAM22243.1 - 0.095 13.6 11.3 0.2 12.5 0.2 3.1 3 0 0 3 3 3 0 Stm1 CAP_N PF01213.19 GAM22243.1 - 1.1 8.7 7.5 0.2 11.1 2.3 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ECM1 PF05782.11 GAM22243.1 - 3.7 6.4 8.9 5.2 5.9 8.9 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) SUIM_assoc PF16619.5 GAM22243.1 - 6.8 6.8 17.5 2.4 8.3 0.2 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 FMN_red PF03358.15 GAM22244.1 - 2e-27 95.8 0.0 2.8e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAM22244.1 - 9.2e-07 28.8 0.0 1.2e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Filo_VP35 PF02097.15 GAM22244.1 - 0.18 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 Ank_2 PF12796.7 GAM22245.1 - 6.7e-48 161.2 15.9 4.2e-09 36.9 0.2 7.3 2 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM22245.1 - 6.7e-44 147.7 17.8 4.1e-08 33.6 0.1 10.8 4 3 9 13 13 13 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM22245.1 - 3.3e-43 145.2 22.4 0.00011 22.5 0.0 16.5 5 3 13 18 18 18 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM22245.1 - 5.7e-21 72.4 15.4 0.27 11.9 0.0 15.4 15 3 3 18 18 18 4 Ankyrin repeat DUF5049 PF16468.5 GAM22245.1 - 8.4e-14 51.2 0.7 5.1 7.1 0.0 12.7 9 3 7 16 16 16 2 Domain of unknown function (DUF5049) Ank PF00023.30 GAM22245.1 - 1.4e-08 34.8 5.4 7.7 7.2 0.0 10.2 3 3 5 8 8 8 1 Ankyrin repeat Cas_Csy1 PF09611.10 GAM22245.1 - 0.0049 16.0 1.7 1.8 7.6 0.0 4.2 2 1 2 5 5 5 1 CRISPR-associated protein (Cas_Csy1) Peptidase_C12 PF01088.21 GAM22246.1 - 1.7e-60 204.4 0.1 2.1e-60 204.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 TetR_C_8 PF14278.6 GAM22246.1 - 0.16 12.1 2.1 4 7.6 0.0 2.9 2 1 1 3 3 3 0 Transcriptional regulator C-terminal region PPR PF01535.20 GAM22248.1 - 0.0031 17.7 0.1 6.5 7.2 0.0 3.3 2 0 0 2 2 2 2 PPR repeat GCFC PF07842.12 GAM22249.1 - 9.1e-56 189.5 5.9 1.6e-55 188.7 5.9 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 GAM22249.1 - 8.2e-09 35.8 18.4 8.2e-09 35.8 18.4 3.5 2 1 1 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.23 GAM22249.1 - 3.5e-08 33.2 1.3 9.6e-08 31.8 1.3 1.8 1 0 0 1 1 1 1 G-patch domain CN_hydrolase PF00795.22 GAM22250.1 - 4.6e-61 206.4 0.0 5.2e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3875 PF12991.7 GAM22250.1 - 0.031 14.2 0.7 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3875) Peptidase_S8 PF00082.22 GAM22251.1 - 2.2e-43 148.7 0.0 3.3e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family ABC_transp_aux PF09822.9 GAM22251.1 - 0.0025 17.3 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system PARP PF00644.20 GAM22252.1 - 7.5e-41 139.9 0.0 1.3e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 GAM22252.1 - 1.2e-37 129.1 0.4 2.2e-37 128.2 0.4 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain PADR1 PF08063.12 GAM22252.1 - 6.9e-19 67.4 2.0 6.9e-19 67.4 2.0 2.1 2 0 0 2 2 2 1 PADR1 (NUC008) domain WGR PF05406.15 GAM22252.1 - 8.4e-16 57.8 0.3 3.1e-15 56.0 0.3 2.0 1 0 0 1 1 1 1 WGR domain zf-PARP PF00645.18 GAM22252.1 - 1.9e-12 47.8 0.2 5.5e-12 46.4 0.2 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region FNIP PF05725.12 GAM22253.1 - 1.9e-72 239.2 22.7 8e-14 51.5 0.2 7.1 5 1 4 9 9 9 8 FNIP Repeat Ank_2 PF12796.7 GAM22254.1 - 0.00026 21.5 2.4 3 8.5 0.0 5.8 5 1 0 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM22254.1 - 0.13 12.8 1.2 5.1e+02 1.8 0.0 6.5 5 0 0 5 5 5 0 Ankyrin repeat zf-C2H2 PF00096.26 GAM22255.1 - 0.088 13.3 3.4 0.088 13.3 3.4 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type XAP5 PF04921.14 GAM22255.1 - 1.4 8.7 5.0 2.1 8.1 5.0 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator RRN3 PF05327.11 GAM22255.1 - 1.7 7.1 7.2 2.1 6.8 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 GAM22255.1 - 3.1 5.8 11.4 3.8 5.5 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Lsm_interact PF05391.11 GAM22255.1 - 4.5 6.9 5.7 0.38 10.3 0.6 1.9 2 0 0 2 2 2 0 Lsm interaction motif hNIFK_binding PF12196.8 GAM22255.1 - 4.7 6.8 6.5 1.5 8.3 1.6 2.5 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK ABC_tran PF00005.27 GAM22256.1 - 1.8e-50 171.0 0.0 5.1e-26 91.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 GAM22256.1 - 4.2e-42 144.5 61.4 6.9e-23 81.3 29.2 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 GAM22256.1 - 3.5e-19 69.7 0.0 2.9e-07 30.6 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM22256.1 - 0.00028 20.4 0.0 2.2 7.7 0.0 3.6 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM22256.1 - 0.00044 19.9 1.5 0.06 13.1 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 GAM22256.1 - 0.0039 16.9 1.7 1.2 8.8 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain AAA_23 PF13476.6 GAM22256.1 - 0.0049 17.4 1.9 3.2 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 GAM22256.1 - 0.0063 16.2 1.3 0.97 9.0 0.2 2.6 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 GAM22256.1 - 0.0083 16.3 0.0 0.82 9.9 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 GAM22256.1 - 0.07 13.0 0.3 3 7.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 GAM22256.1 - 0.093 12.8 0.2 10 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Cofilin_ADF PF00241.20 GAM22257.1 - 8.7e-35 119.2 0.0 1.3e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Rhomboid PF01694.22 GAM22258.1 - 7.1e-24 84.5 8.2 1.1e-23 83.8 8.2 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 GAM22258.1 - 0.036 14.6 0.1 0.11 13.0 0.1 1.9 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) FUSC-like PF12805.7 GAM22258.1 - 0.88 8.6 5.5 0.081 12.0 0.6 1.7 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DUF702 PF05142.12 GAM22259.1 - 1.7e-05 25.3 8.7 1.7e-05 25.3 8.7 2.5 3 1 1 4 4 4 1 Domain of unknown function (DUF702) Rad4 PF03835.15 GAM22259.1 - 0.055 13.1 2.3 0.15 11.7 2.3 1.7 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain DUF3530 PF12048.8 GAM22259.1 - 0.41 10.0 6.6 0.051 13.0 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Pox_Ag35 PF03286.14 GAM22259.1 - 7.6 6.3 15.9 2.2 8.0 12.2 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Kelch_1 PF01344.25 GAM22260.1 - 0.015 14.9 0.1 0.046 13.3 0.1 1.8 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.6 GAM22260.1 - 0.11 12.8 0.3 0.3 11.5 0.2 1.8 2 0 0 2 2 2 0 Kelch motif LRR_8 PF13855.6 GAM22261.1 - 1.3e-20 72.8 14.7 6.2e-09 35.5 0.7 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAM22261.1 - 6.4e-12 45.5 9.8 3.4e-06 27.3 1.1 4.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAM22261.1 - 0.00024 20.9 6.3 1.3 9.3 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 GAM22261.1 - 0.0058 16.2 1.2 0.012 15.2 1.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 GAM22261.1 - 0.38 11.5 16.5 7 7.6 0.1 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat rhaM PF05336.13 GAM22262.1 - 7.1e-27 93.6 1.0 7.9e-27 93.4 1.0 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase HEPN_AbiV PF18728.1 GAM22262.1 - 0.0053 16.9 0.4 0.33 11.1 0.0 2.0 2 0 0 2 2 2 2 AbiV PPR_2 PF13041.6 GAM22263.1 - 0.0053 16.9 0.1 3.8 7.8 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family Rgp1 PF08737.10 GAM22264.1 - 3.5e-38 131.9 6.3 1.9e-25 90.0 0.3 3.6 2 1 2 4 4 4 2 Rgp1 TFIIA PF03153.13 GAM22264.1 - 1.6 8.7 19.0 0.039 13.9 8.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.22 GAM22265.1 - 9.2e-93 311.5 0.3 1e-92 311.3 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 EGF_2 PF07974.13 GAM22266.1 - 3.9e-06 27.1 13.2 8.6e-06 26.0 13.2 1.6 1 0 0 1 1 1 1 EGF-like domain TIG PF01833.24 GAM22266.1 - 5.3e-05 23.2 69.9 0.00043 20.3 1.2 10.3 10 1 0 11 11 11 8 IPT/TIG domain Laminin_EGF PF00053.24 GAM22266.1 - 1.4 9.1 9.4 2.9 8.1 9.4 1.5 1 0 0 1 1 1 0 Laminin EGF domain TIG PF01833.24 GAM22267.1 - 6.5e-55 183.2 100.3 4e-10 39.6 0.5 15.1 14 1 1 15 15 15 12 IPT/TIG domain DNase_II PF03265.15 GAM22267.1 - 3.1e-30 105.6 1.2 1.9e-18 66.9 2.1 2.4 2 0 0 2 2 2 2 Deoxyribonuclease II SdrD_B PF17210.3 GAM22267.1 - 0.0065 16.7 0.1 0.0065 16.7 0.1 2.8 4 0 0 4 4 4 1 SdrD B-like domain RXT2_N PF08595.11 GAM22268.1 - 0.019 15.0 2.5 0.04 14.0 2.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 GAM22268.1 - 0.19 12.1 8.7 0.41 11.1 8.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 GAM22268.1 - 0.22 11.1 1.8 0.48 10.1 1.8 1.5 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 GAM22268.1 - 0.45 10.2 8.9 0.73 9.5 8.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 GAM22268.1 - 0.82 9.5 4.2 1.2 8.9 4.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 GAM22268.1 - 0.94 7.7 4.8 1.4 7.2 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein FSA_C PF10479.9 GAM22268.1 - 1.8 6.6 4.8 2.2 6.3 4.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 GAM22268.1 - 1.9 6.6 15.6 2.4 6.2 15.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RRN3 PF05327.11 GAM22268.1 - 3.9 5.9 5.2 5.8 5.3 5.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Utp14 PF04615.13 GAM22268.1 - 5.6 5.4 7.0 8.8 4.8 7.0 1.2 1 0 0 1 1 1 0 Utp14 protein zf-C2H2_aberr PF17017.5 GAM22268.1 - 6 7.0 18.3 14 5.8 0.3 4.4 3 1 1 4 4 4 0 Aberrant zinc-finger FOXP-CC PF16159.5 GAM22268.1 - 6.7 7.4 11.6 2.9 8.6 1.4 3.2 2 1 0 3 3 3 0 FOXP coiled-coil domain CENP-B_dimeris PF09026.10 GAM22268.1 - 6.9 7.1 19.1 19 5.7 19.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 GAM22268.1 - 7.1 4.7 7.8 12 4.0 7.8 1.2 1 0 0 1 1 1 0 Nop14-like family Methyltransf_11 PF08241.12 GAM22270.1 - 9.3e-17 61.5 0.0 1.9e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM22270.1 - 1.5e-13 51.2 0.0 6.9e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM22270.1 - 3.8e-07 30.8 0.0 8.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM22270.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM22270.1 - 2e-06 27.3 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAM22270.1 - 0.0002 21.2 0.0 0.00034 20.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAM22270.1 - 0.00095 19.1 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 Hypothetical methyltransferase RrnaAD PF00398.20 GAM22270.1 - 0.009 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 GAM22270.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Catalase-rel PF06628.12 GAM22270.1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Catalase-related immune-responsive AAA PF00004.29 GAM22271.1 - 7.6e-50 168.7 0.1 1.3e-34 119.5 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM22271.1 - 1.4e-13 50.4 0.1 1.2e-07 31.4 0.1 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 GAM22271.1 - 6.1e-11 43.0 0.2 0.00027 21.4 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAM22271.1 - 5.3e-07 30.0 0.0 0.00054 20.3 0.0 3.5 2 2 1 3 3 3 1 AAA domain RuvB_N PF05496.12 GAM22271.1 - 4e-06 26.7 0.0 0.00099 18.9 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 GAM22271.1 - 6.3e-06 26.2 0.1 0.0036 17.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM22271.1 - 2.2e-05 25.0 0.0 0.0028 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAM22271.1 - 3.6e-05 23.8 0.1 0.00048 20.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAM22271.1 - 4.7e-05 23.6 0.0 0.00039 20.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ATPase_2 PF01637.18 GAM22271.1 - 5.4e-05 23.2 0.2 0.33 10.8 0.0 3.3 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 GAM22271.1 - 5.9e-05 22.4 0.0 0.07 12.3 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 GAM22271.1 - 0.0001 22.1 0.0 0.021 14.6 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 GAM22271.1 - 0.00013 21.3 0.1 0.0093 15.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 GAM22271.1 - 0.00026 21.3 0.1 0.2 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAM22271.1 - 0.00047 20.3 0.0 0.011 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAM22271.1 - 0.00083 19.7 0.0 1.1 9.7 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Mg_chelatase PF01078.21 GAM22271.1 - 0.0011 18.4 0.0 0.19 11.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GAM22271.1 - 0.0029 17.2 0.2 2.8 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 GAM22271.1 - 0.0037 16.6 0.6 0.25 10.6 0.0 3.3 3 1 0 4 4 4 1 KaiC Vps4_C PF09336.10 GAM22271.1 - 0.0042 17.0 0.0 0.086 12.8 0.0 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain NACHT PF05729.12 GAM22271.1 - 0.0085 16.0 0.3 2.4 8.0 0.0 3.7 2 2 2 4 4 4 1 NACHT domain Sigma54_activat PF00158.26 GAM22271.1 - 0.0085 15.8 0.1 0.15 11.8 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 GAM22271.1 - 0.011 15.4 0.3 0.47 10.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain Bac_DnaA PF00308.18 GAM22271.1 - 0.017 15.0 0.2 0.96 9.2 0.0 3.1 2 2 0 2 2 2 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 GAM22271.1 - 0.023 13.8 0.0 5.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 GAM22271.1 - 0.035 14.1 0.0 0.87 9.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 GAM22271.1 - 0.036 14.0 0.1 1.2 9.0 0.0 2.9 2 1 0 3 3 3 0 Rad17 P-loop domain AAA_7 PF12775.7 GAM22271.1 - 0.043 13.3 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Zot PF05707.12 GAM22271.1 - 0.048 13.3 0.1 0.92 9.1 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) PhoH PF02562.16 GAM22271.1 - 0.059 12.8 0.0 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 GAM22271.1 - 0.098 11.8 0.0 15 4.7 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain Zeta_toxin PF06414.12 GAM22271.1 - 0.11 11.8 0.1 4 6.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 GAM22271.1 - 0.15 12.6 0.1 22 5.6 0.0 2.7 2 1 0 2 2 2 0 ABC transporter zf-C2H2_aberr PF17017.5 GAM22273.1 - 0.054 13.6 0.9 0.054 13.6 0.9 3.9 4 1 1 5 5 5 0 Aberrant zinc-finger Zip PF02535.22 GAM22274.1 - 0.58 9.3 6.4 0.57 9.3 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ALMT PF11744.8 GAM22274.1 - 4.8 5.9 12.8 6.1 5.6 12.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Velvet PF11754.8 GAM22274.1 - 8.1 6.3 11.5 14 5.6 11.4 1.4 1 1 0 1 1 1 0 Velvet factor Methyltransf_25 PF13649.6 GAM22275.1 - 0.00085 20.0 0.1 0.0028 18.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM22275.1 - 0.26 12.0 0.0 0.26 12.0 0.0 2.7 3 1 0 3 3 3 0 Methyltransferase domain SLX9 PF15341.6 GAM22278.1 - 1.7e-18 67.3 12.8 1.7e-18 67.3 12.8 2.3 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 SUIM_assoc PF16619.5 GAM22278.1 - 0.0071 16.4 2.7 0.0071 16.4 2.7 3.3 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 PRP1_N PF06424.12 GAM22278.1 - 1.7 9.0 19.7 0.036 14.5 10.7 2.6 2 1 1 3 3 3 0 PRP1 splicing factor, N-terminal PhyH PF05721.13 GAM22279.1 - 7.7e-27 94.9 0.1 1e-26 94.6 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4508 PF14969.6 GAM22280.1 - 0.011 15.9 0.0 0.11 12.7 0.0 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4508) HEAT_EZ PF13513.6 GAM22281.1 - 8.2e-29 99.6 10.1 8.5e-12 45.3 0.0 9.2 9 0 0 9 9 8 3 HEAT-like repeat HEAT_2 PF13646.6 GAM22281.1 - 1.6e-15 57.2 0.0 0.0018 18.6 0.0 6.5 4 2 3 7 7 7 4 HEAT repeats HEAT PF02985.22 GAM22281.1 - 5.1e-15 54.3 12.1 0.021 15.1 0.0 10.5 12 0 0 12 12 10 3 HEAT repeat Vac14_Fab1_bd PF12755.7 GAM22281.1 - 6.6e-13 49.1 0.5 0.077 13.6 0.0 6.0 3 2 2 5 5 5 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAM22281.1 - 2.7e-10 40.5 4.3 0.033 14.2 0.0 4.8 3 1 2 5 5 5 4 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 GAM22281.1 - 6.1e-07 29.5 4.4 0.031 14.2 0.0 5.2 6 1 1 7 7 6 2 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 GAM22281.1 - 0.00017 20.3 10.3 0.68 8.4 0.3 4.2 3 1 0 3 3 3 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 GAM22281.1 - 0.00021 20.7 2.1 2 7.7 0.4 4.7 3 2 0 4 4 4 1 V-ATPase subunit H MMS19_C PF12460.8 GAM22281.1 - 0.00022 20.5 8.7 0.29 10.2 0.4 4.5 3 2 1 4 4 4 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 GAM22281.1 - 0.00072 19.7 0.4 2.9 8.1 0.0 4.0 3 1 0 3 3 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 GAM22281.1 - 0.00073 19.5 22.4 2.6 8.2 0.0 7.5 9 0 0 9 9 7 2 Armadillo/beta-catenin-like repeat RNA_pol_3_Rpc31 PF11705.8 GAM22281.1 - 0.0066 16.7 10.4 0.01 16.1 10.4 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 IBN_N PF03810.19 GAM22281.1 - 0.0067 16.3 0.0 0.03 14.2 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3437 PF11919.8 GAM22281.1 - 0.01 15.7 0.0 0.92 9.5 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) Tti2 PF10521.9 GAM22281.1 - 0.012 15.1 11.3 0.54 9.8 0.2 5.4 3 2 2 5 5 5 0 Tti2 family TIP120 PF08623.10 GAM22281.1 - 0.021 14.6 3.1 0.32 10.8 0.3 4.0 5 0 0 5 5 5 0 TATA-binding protein interacting (TIP20) RRN3 PF05327.11 GAM22281.1 - 0.077 11.5 9.7 0.1 11.1 8.7 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 GAM22281.1 - 0.095 12.1 10.7 0.14 11.6 10.7 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 GAM22281.1 - 0.11 12.1 9.4 0.2 11.2 9.4 1.4 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 GAM22281.1 - 0.14 10.4 9.2 0.22 9.7 9.2 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GAM22281.1 - 0.21 9.6 18.2 0.54 8.3 18.2 1.6 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 GAM22281.1 - 0.51 10.7 1.6 0.95 9.9 1.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sporozoite_P67 PF05642.11 GAM22281.1 - 0.68 7.9 2.5 1 7.4 2.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4820 PF16091.5 GAM22281.1 - 0.75 9.1 3.1 1.4 8.3 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 GAM22281.1 - 1.9 8.2 5.7 4.9 6.8 5.7 1.7 1 0 0 1 1 1 0 FAM176 family CobT PF06213.12 GAM22281.1 - 3.1 7.1 12.9 5.2 6.4 12.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 GAM22281.1 - 6.5 4.9 10.7 11 4.2 10.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 GAM22281.1 - 7 5.7 9.6 12 5.0 9.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2462 PF09495.10 GAM22282.1 - 0.00016 22.3 8.2 0.00016 22.3 8.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) Gelsolin PF00626.22 GAM22283.1 - 2.9e-22 78.4 0.3 1.5e-07 31.2 0.0 6.1 5 0 0 5 5 5 4 Gelsolin repeat SSP160 PF06933.11 GAM22283.1 - 0.79 7.8 6.3 1.7 6.8 6.3 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ADK PF00406.22 GAM22284.1 - 3.2e-58 196.1 0.0 4e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAM22284.1 - 1.4e-22 80.6 0.0 3.1e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 GAM22284.1 - 4.4e-17 61.8 0.0 8.8e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid RuvB_N PF05496.12 GAM22284.1 - 0.0045 16.7 0.0 0.03 14.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Hydin_ADK PF17213.3 GAM22284.1 - 0.013 15.8 0.1 0.78 10.0 0.0 2.4 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 GAM22284.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAM22284.1 - 0.056 14.0 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAM22284.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain BORCS6 PF10157.9 GAM22285.1 - 3e-09 37.3 16.0 3e-09 37.3 16.0 3.4 2 2 0 2 2 2 1 BLOC-1-related complex sub-unit 6 Med3 PF11593.8 GAM22285.1 - 0.002 17.4 17.2 0.002 17.4 17.2 3.3 2 2 0 2 2 2 1 Mediator complex subunit 3 fungal Hydrophobin_2 PF06766.11 GAM22285.1 - 0.077 13.0 0.2 0.21 11.6 0.2 1.7 1 0 0 1 1 1 0 Fungal hydrophobin E2F_CC-MB PF16421.5 GAM22286.1 - 1.1e-27 96.2 1.5 9.1e-27 93.3 0.3 2.6 2 0 0 2 2 2 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 GAM22286.1 - 7.1e-20 70.8 0.2 1.7e-19 69.6 0.1 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain PBP1_TM PF14812.6 GAM22286.1 - 0.16 12.4 2.1 0.41 11.1 2.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dak1 PF02733.17 GAM22287.1 - 2.4e-110 368.3 2.9 3.2e-110 367.9 2.9 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 GAM22287.1 - 2.2e-45 154.7 0.0 4.9e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 DAK2 domain ASCH PF04266.14 GAM22287.1 - 9.4e-13 48.7 0.0 1.8e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 ASCH domain SapB_1 PF05184.15 GAM22287.1 - 0.13 12.3 1.3 26 4.9 0.1 3.5 3 0 0 3 3 3 0 Saposin-like type B, region 1 C2 PF00168.30 GAM22288.1 - 1.3e-16 60.7 0.1 3.8e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 C2 domain GRAM PF02893.20 GAM22288.1 - 6.1e-08 32.6 4.0 1.1e-07 31.7 0.2 2.7 2 0 0 2 2 2 1 GRAM domain Membr_traf_MHD PF10540.9 GAM22288.1 - 5.9e-06 26.5 1.7 0.018 15.2 0.0 4.0 3 1 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain Baculo_PEP_C PF04513.12 GAM22288.1 - 2.5 8.2 7.9 1.3 9.1 2.6 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SPC25 PF06703.11 GAM22289.1 - 4.8e-36 124.0 0.0 6.2e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Caps_synth_CapC PF14102.6 GAM22289.1 - 0.011 16.1 0.9 0.059 13.8 0.2 2.0 2 0 0 2 2 2 0 Capsule biosynthesis CapC 7tm_3 PF00003.22 GAM22289.1 - 0.034 13.9 0.0 0.039 13.7 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR BLACT_WH PF17778.1 GAM22290.1 - 8.9e-09 35.2 0.1 1.6e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 GAM22290.1 - 6.1e-06 26.4 1.2 1.8e-05 24.9 1.2 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM22290.1 - 4.4e-05 23.1 0.2 6.7e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1993 PF09351.10 GAM22291.1 - 6 7.0 11.5 0.55 10.4 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) Mitofilin PF09731.9 GAM22292.1 - 3.7e-38 131.8 40.2 1.1e-37 130.2 40.2 1.7 1 1 0 1 1 1 1 Mitochondrial inner membrane protein DUF4366 PF14283.6 GAM22292.1 - 0.0018 18.3 0.0 0.0018 18.3 0.0 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4366) TPR_14 PF13428.6 GAM22292.1 - 0.094 13.6 1.0 1.4 9.9 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat NifU PF01106.17 GAM22292.1 - 0.094 12.9 0.0 0.39 10.9 0.0 2.1 1 0 0 1 1 1 0 NifU-like domain PHD PF00628.29 GAM22294.1 - 1.1e-10 41.3 27.2 7.3e-09 35.4 9.4 2.6 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 GAM22294.1 - 0.0017 17.9 6.2 0.0017 17.9 6.2 2.4 2 0 0 2 2 2 1 PHD-finger FancD2 PF14631.6 GAM22294.1 - 7.6 3.8 19.6 0.0033 14.9 6.1 1.9 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease PP-binding PF00550.25 GAM22295.1 - 2.1e-11 44.0 0.1 2.6e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GAM22295.1 - 0.00086 19.5 0.4 0.0015 18.7 0.4 1.4 1 1 0 1 1 1 1 Acyl-carrier LRR_6 PF13516.6 GAM22296.1 - 2.3e-18 64.6 21.4 0.00016 21.5 0.1 9.8 9 0 0 9 9 9 5 Leucine Rich repeat PK PF00224.21 GAM22296.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain LRR_4 PF12799.7 GAM22296.1 - 0.018 15.4 43.9 0.073 13.5 3.8 8.7 6 2 3 9 9 9 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM22296.1 - 0.096 13.3 26.0 3.5 8.6 0.0 9.7 8 3 1 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 GAM22296.1 - 0.28 11.0 36.8 0.32 10.8 3.6 8.2 5 2 1 7 7 7 0 Leucine rich repeat PET117 PF15786.5 GAM22297.1 - 0.0042 17.3 0.6 0.032 14.5 0.0 2.8 2 2 0 2 2 2 1 PET assembly of cytochrome c oxidase, mitochondrial PPR PF01535.20 GAM22297.1 - 0.15 12.4 0.1 4 7.9 0.0 3.1 3 0 0 3 3 3 0 PPR repeat PhoU PF01895.19 GAM22297.1 - 0.2 12.1 1.5 0.46 11.0 0.0 2.4 3 0 0 3 3 3 0 PhoU domain FKBP_N PF01346.18 GAM22297.1 - 1.7 9.7 13.4 1.4 9.9 2.6 3.0 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Thg1 PF04446.12 GAM22298.1 - 1.7e-52 176.7 0.2 2.3e-52 176.2 0.2 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 GAM22298.1 - 1.1e-43 148.3 1.0 2.8e-43 146.9 1.0 1.6 1 1 0 1 1 1 1 Thg1 C terminal domain Kelch_6 PF13964.6 GAM22299.1 - 7.3e-10 38.8 11.1 9e-05 22.6 0.0 4.8 4 2 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAM22299.1 - 1.1e-06 28.1 4.1 0.77 9.4 0.1 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 GAM22299.1 - 0.0086 16.0 1.0 21 5.3 0.0 3.7 3 0 0 3 3 3 0 Kelch motif Baculo_PEP_C PF04513.12 GAM22299.1 - 0.055 13.5 12.1 0.045 13.8 10.2 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACDC PF14733.6 GAM22299.1 - 0.19 12.0 5.4 0.25 11.7 2.5 2.7 2 1 1 3 3 3 0 AP2-coincident C-terminal Kelch_4 PF13418.6 GAM22299.1 - 0.28 11.2 13.3 2.6 8.1 0.2 5.0 6 0 0 6 6 6 0 Galactose oxidase, central domain DUF3823_C PF18003.1 GAM22299.1 - 0.29 11.9 3.2 0.86 10.3 3.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3823_C) Alpha-2-MRAP_C PF06401.11 GAM22299.1 - 0.45 10.4 2.2 0.51 10.3 0.3 1.9 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Kelch_5 PF13854.6 GAM22299.1 - 0.47 10.5 10.0 1.7 8.7 0.3 4.1 4 0 0 4 4 4 0 Kelch motif Phage_sheath_1C PF17482.2 GAM22299.1 - 0.47 10.4 6.0 0.21 11.5 2.3 2.1 2 0 0 2 2 2 0 Phage tail sheath C-terminal domain Kelch_6 PF13964.6 GAM22300.1 - 2.4e-13 49.8 1.7 1.4e-05 25.2 0.0 3.7 1 1 2 3 3 3 2 Kelch motif Kelch_4 PF13418.6 GAM22300.1 - 1.8e-08 34.2 0.3 3.6e-05 23.7 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM22300.1 - 1.4e-07 31.0 0.1 0.017 14.7 0.0 2.7 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 GAM22300.1 - 4.4e-05 23.6 0.1 0.41 11.0 0.0 3.4 2 1 1 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM22300.1 - 0.0009 19.1 0.0 0.22 11.6 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 GAM22300.1 - 0.00091 19.2 1.0 5.7 7.0 0.0 3.3 3 0 0 3 3 3 2 Kelch motif BTB PF00651.31 GAM22301.1 - 1.4e-18 67.2 0.2 3.3e-18 65.9 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 GAM22301.1 - 3.1e-06 27.3 0.9 5.7e-06 26.5 0.2 1.9 2 0 0 2 2 2 1 MATH domain BACK PF07707.15 GAM22301.1 - 3.3e-06 27.1 0.0 9.5e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 BTB And C-terminal Kelch Ribosomal_L34e PF01199.18 GAM22302.1 - 2.1e-41 140.1 5.7 2.1e-41 140.1 5.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L34e Zn-ribbon_8 PF09723.10 GAM22302.1 - 0.019 15.1 1.0 0.046 13.8 0.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 GAM22302.1 - 0.059 13.4 1.0 5.1 7.2 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbons Nkap_C PF06047.11 GAM22302.1 - 0.071 13.2 0.9 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain Glyco_transf_10 PF00852.19 GAM22303.1 - 4.7e-37 127.4 5.8 7.3e-37 126.8 2.8 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 GAM22303.1 - 1.9e-06 28.3 2.1 2.2e-06 28.1 0.1 2.1 2 1 0 2 2 2 1 Fucosyltransferase, N-terminal BRAP2 PF07576.12 GAM22303.1 - 1.4 9.2 5.8 9.1 6.6 0.3 2.7 3 0 0 3 3 3 0 BRCA1-associated protein 2 RMI1_N PF08585.12 GAM22304.1 - 9.6e-23 81.1 2.0 7.7e-22 78.1 0.0 2.6 1 1 2 3 3 3 1 RecQ mediated genome instability protein RMI1_C PF16099.5 GAM22304.1 - 1.1e-06 28.6 0.1 2.7e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Ecl1 PF12855.7 GAM22304.1 - 0.39 11.9 4.5 0.55 11.4 0.3 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins PPTA PF01239.22 GAM22305.1 - 2.3e-18 65.3 9.3 3.6e-06 26.5 1.4 5.5 6 0 0 6 6 6 4 Protein prenyltransferase alpha subunit repeat TRM PF02005.16 GAM22306.1 - 1.6e-126 422.5 0.1 2.1e-126 422.1 0.1 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase zf_CCCH_4 PF18345.1 GAM22306.1 - 0.00045 20.2 1.1 0.0026 17.8 0.2 2.7 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 GAM22306.1 - 0.0007 19.4 4.5 0.0011 18.8 1.4 2.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAM22306.1 - 0.0012 19.6 0.9 0.0031 18.2 0.9 1.7 1 0 0 1 1 1 1 Torus domain Met_10 PF02475.16 GAM22306.1 - 0.0054 16.5 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 GAM22306.1 - 0.035 13.5 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SNF2_N PF00176.23 GAM22307.1 - 5.7e-72 242.4 0.1 5.7e-72 242.4 0.1 3.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM22307.1 - 3.9e-20 72.2 0.1 8.3e-19 68.0 0.0 3.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 GAM22307.1 - 5.3e-20 71.3 1.2 1.5e-19 69.8 0.3 2.4 2 0 0 2 2 2 1 Bromodomain HSA PF07529.13 GAM22307.1 - 5.2e-15 55.5 11.6 5.2e-15 55.5 11.6 4.6 2 1 2 4 4 4 1 HSA RPN5_C PF18098.1 GAM22307.1 - 0.12 12.5 0.2 0.33 11.1 0.2 1.8 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain Peptidase_S8 PF00082.22 GAM22308.1 - 2.7e-39 135.2 5.9 4e-39 134.6 5.9 1.3 1 0 0 1 1 1 1 Subtilase family FANCI_S1-cap PF14674.6 GAM22309.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 FANCI solenoid 1 cap SRP19 PF01922.17 GAM22310.1 - 1.3e-27 96.6 0.0 2.1e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein TPR_MLP1_2 PF07926.12 GAM22311.1 - 0.025 14.6 0.7 0.052 13.6 0.7 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 GAM22311.1 - 0.03 14.0 1.0 0.044 13.5 1.0 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_1 PF00170.21 GAM22311.1 - 0.13 12.4 2.1 0.3 11.2 2.1 1.6 1 0 0 1 1 1 0 bZIP transcription factor ZapB PF06005.12 GAM22311.1 - 0.16 12.4 3.1 0.29 11.6 3.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 GAM22311.1 - 0.26 11.4 1.2 0.44 10.7 0.7 1.7 1 1 0 1 1 1 0 Basic region leucine zipper Nkap_C PF06047.11 GAM22312.1 - 1.7e-45 153.3 3.0 1.7e-45 153.3 3.0 2.5 3 0 0 3 3 3 1 NF-kappa-B-activating protein C-terminal domain RCC1 PF00415.18 GAM22313.1 - 9.7e-38 128.6 3.1 6.6e-12 45.9 0.0 7.1 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM22313.1 - 5.4e-29 99.4 11.9 2.7e-09 36.6 0.1 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Ribosomal_L26 PF16906.5 GAM22314.1 - 2.9e-36 123.8 3.3 3.9e-36 123.4 3.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 GAM22314.1 - 1.7e-07 30.9 2.5 5.1e-07 29.4 2.5 1.8 1 0 0 1 1 1 1 KOW motif Urm1 PF09138.11 GAM22315.1 - 4.7e-33 113.4 0.1 5.4e-33 113.2 0.1 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 GAM22315.1 - 0.00032 21.3 0.0 0.00052 20.6 0.0 1.4 1 1 0 1 1 1 1 ThiS family DnaJ PF00226.31 GAM22316.1 - 7.8e-07 29.1 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 GAM22316.1 - 1e-05 25.6 0.1 1.3e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 Pam16 Cro PF09048.10 GAM22316.1 - 0.044 13.8 0.4 0.086 12.9 0.0 1.6 2 0 0 2 2 2 0 Cro Mito_carr PF00153.27 GAM22317.1 - 1.2e-62 207.9 4.2 2.6e-22 78.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rad52_Rad22 PF04098.15 GAM22318.1 - 4.7e-07 29.8 0.0 1.1e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.22 GAM22318.1 - 2.7e-06 27.1 0.0 5.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM22318.1 - 0.00027 20.5 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.9 GAM22318.1 - 0.091 12.4 8.4 0.15 11.7 8.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 GAM22318.1 - 2.1 9.1 7.8 4.3 8.1 7.8 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein BK_channel_a PF03493.18 GAM22319.1 - 6.8e-22 77.5 0.2 1.1e-20 73.6 0.1 2.8 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 GAM22319.1 - 2e-14 53.3 6.8 8.5e-14 51.3 6.8 2.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 GAM22319.1 - 3.3e-11 42.9 21.7 5.5e-10 38.9 21.7 2.3 1 1 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 GAM22319.1 - 1.6e-06 28.3 0.0 0.00047 20.4 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain Castor_Poll_mid PF06241.12 GAM22319.1 - 0.00077 19.4 0.0 0.49 10.4 0.0 3.3 3 1 0 3 3 3 1 Castor and Pollux, part of voltage-gated ion channel Mito_fiss_reg PF05308.11 GAM22319.1 - 0.51 10.4 6.7 0.35 10.9 0.8 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator RRN3 PF05327.11 GAM22319.1 - 1.1 7.7 4.7 1.9 6.9 4.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 STE3 PF02076.15 GAM22320.1 - 0.042 13.0 1.0 0.11 11.7 0.3 1.8 2 0 0 2 2 2 0 Pheromone A receptor CaKB PF03185.15 GAM22320.1 - 0.06 13.0 4.2 4.2 7.0 0.5 3.1 2 1 1 3 3 3 0 Calcium-activated potassium channel, beta subunit VKOR PF07884.14 GAM22320.1 - 0.46 10.7 4.2 10 6.3 0.0 2.5 3 0 0 3 3 3 0 Vitamin K epoxide reductase family RasGEF_N PF00618.20 GAM22321.1 - 3 8.1 15.2 0.4 10.9 0.5 4.9 4 0 0 4 4 4 0 RasGEF N-terminal motif Nup188 PF10487.9 GAM22322.1 - 9.9e-17 60.2 9.7 1.2e-16 59.8 9.7 1.1 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Pkinase PF00069.25 GAM22323.1 - 2.4e-45 155.0 0.5 2.4e-45 155.0 0.5 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22323.1 - 2.3e-25 89.3 0.0 3.5e-24 85.5 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM22323.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4746 PF15928.5 GAM22323.1 - 0.17 11.3 8.3 0.31 10.4 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Plasmodium_Vir PF05795.11 GAM22323.1 - 0.23 10.8 3.7 0.6 9.5 3.7 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Spt20 PF12090.8 GAM22323.1 - 0.49 10.0 26.2 0.021 14.4 18.8 2.3 2 0 0 2 2 2 0 Spt20 family Roughex PF06020.11 GAM22323.1 - 0.54 9.3 11.8 0.84 8.7 11.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Lin-8 PF03353.15 GAM22323.1 - 0.83 9.2 10.8 3 7.3 8.9 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 GAM22323.1 - 1 8.0 9.5 1.7 7.3 9.5 1.3 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 GAM22323.1 - 7.8 6.4 15.9 0.1 12.6 7.6 2.1 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) PB1 PF00564.24 GAM22324.1 - 1.5e-14 53.7 0.2 2.5e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 PB1 domain DUF3454 PF11936.8 GAM22324.1 - 0.015 15.6 3.1 0.015 15.6 3.1 4.7 3 1 0 4 4 4 0 Domain of unknown function (DUF3454) Acetyltransf_1 PF00583.25 GAM22325.1 - 7.7e-14 51.9 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM22325.1 - 3.1e-11 43.6 0.2 7.2e-11 42.4 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM22325.1 - 1.9e-10 40.8 0.3 5.1e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM22325.1 - 1.6e-06 28.0 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAM22325.1 - 0.0098 16.0 0.2 0.022 14.9 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAM22325.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GATA PF00320.27 GAM22326.1 - 5.1e-15 54.8 5.4 1.4e-14 53.4 5.4 1.8 1 0 0 1 1 1 1 GATA zinc finger MAP70 PF07058.11 GAM22326.1 - 0.099 11.4 0.0 0.099 11.4 0.0 1.6 2 0 0 2 2 2 0 Microtubule-associated protein 70 GlcNAc PF11397.8 GAM22327.1 - 4.1e-88 296.2 0.0 1.6e-87 294.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) CH PF00307.31 GAM22330.1 - 1.4e-15 57.4 0.0 9.5e-08 32.2 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain Ras_bdg_2 PF14847.6 GAM22330.1 - 0.015 15.7 0.7 1.9 8.9 0.0 3.5 3 0 0 3 3 3 0 Ras-binding domain of Byr2 PQ-loop PF04193.14 GAM22331.1 - 5.5e-19 67.7 8.6 1.7e-13 50.1 1.5 3.2 4 0 0 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 GAM22331.1 - 0.012 16.5 2.8 2.1 9.1 0.3 2.5 2 0 0 2 2 2 0 ER lumen protein retaining receptor zf-C2H2_jaz PF12171.8 GAM22332.1 - 5.5e-07 29.7 2.4 1.7e-06 28.2 2.4 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM22332.1 - 4e-06 27.0 3.1 1.1e-05 25.7 3.1 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GAM22332.1 - 0.0042 17.0 0.8 0.0094 15.9 0.8 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger LYRIC PF15686.5 GAM22332.1 - 0.0081 15.8 4.0 0.012 15.2 4.0 1.2 1 0 0 1 1 1 1 Lysine-rich CEACAM1 co-isolated protein family zf-LYAR PF08790.11 GAM22332.1 - 0.0096 15.8 1.5 0.024 14.5 1.5 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 GAM22332.1 - 0.018 15.3 2.2 0.059 13.7 2.2 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAM22332.1 - 0.022 15.6 0.4 0.098 13.5 0.4 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM22332.1 - 0.56 10.8 3.3 0.78 10.3 1.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Cupin_8 PF13621.6 GAM22333.1 - 1.2e-50 172.7 0.4 1.9e-50 172.0 0.0 1.5 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 GAM22333.1 - 1.5e-07 31.2 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 GAM22333.1 - 0.0046 17.4 0.0 0.0099 16.3 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Rax2 PF12768.7 GAM22334.1 - 0.043 13.3 3.3 0.056 12.9 0.0 2.5 2 1 0 2 2 2 0 Cortical protein marker for cell polarity FixQ PF05545.11 GAM22334.1 - 0.081 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Syndecan PF01034.20 GAM22334.1 - 0.11 12.4 1.5 0.22 11.4 1.5 1.4 1 0 0 1 1 1 0 Syndecan domain Candida_ALS PF05792.13 GAM22335.1 - 0.15 12.7 4.5 0.82 10.3 4.5 2.3 1 0 0 1 1 1 0 Candida agglutinin-like (ALS) FixQ PF05545.11 GAM22335.1 - 0.15 12.0 0.2 0.31 11.0 0.2 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Syndecan PF01034.20 GAM22335.1 - 0.2 11.6 1.6 0.39 10.7 1.6 1.4 1 0 0 1 1 1 0 Syndecan domain DnaJ PF00226.31 GAM22336.1 - 5.3e-24 84.1 0.7 6.7e-24 83.8 0.7 1.1 1 0 0 1 1 1 1 DnaJ domain CsiD PF08943.10 GAM22336.1 - 0.081 12.0 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 CsiD DnaJ_C PF01556.18 GAM22337.1 - 2.8e-35 121.6 0.6 3.4e-35 121.3 0.6 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 GAM22337.1 - 8.2e-14 51.7 20.8 1.4e-13 50.9 20.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAM22337.1 - 3.1e-05 23.8 12.7 0.00017 21.5 1.4 2.8 2 1 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 GAM22337.1 - 7.8e-05 22.7 7.3 0.0048 16.9 2.0 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 GAM22337.1 - 0.098 12.3 7.8 0.32 10.6 1.3 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 MCM_OB PF17207.3 GAM22337.1 - 0.16 11.8 7.1 0.095 12.6 1.1 2.1 1 1 1 2 2 2 0 MCM OB domain zinc_ribbon_9 PF14369.6 GAM22337.1 - 0.17 12.2 6.2 8 6.8 0.0 3.4 3 1 0 3 3 3 0 zinc-ribbon zf-RING_10 PF16685.5 GAM22337.1 - 0.2 11.8 7.0 0.13 12.4 0.7 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 GAM22337.1 - 0.81 9.6 8.4 0.26 11.2 1.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 GAM22337.1 - 1.4 9.0 12.8 54 3.9 12.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 GAM22337.1 - 6.1 7.3 11.2 4.2 7.8 0.3 3.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-RING_5 PF14634.6 GAM22337.1 - 8 6.5 11.3 4.1 7.5 2.5 2.3 2 0 0 2 2 2 0 zinc-RING finger domain RhoGEF PF00621.20 GAM22338.1 - 3.8e-50 170.7 1.8 6.8e-50 169.8 1.8 1.4 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 GAM22338.1 - 7.6e-21 74.0 7.6 7.6e-21 74.0 7.6 2.3 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 GAM22338.1 - 9.6e-07 29.3 0.0 2.9e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 GAM22338.1 - 0.0056 16.9 5.8 0.0056 16.9 5.8 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger zf-B_box PF00643.24 GAM22338.1 - 5.5 7.2 11.6 1.2 9.3 7.0 2.2 2 0 0 2 2 2 0 B-box zinc finger zf-MYND PF01753.18 GAM22339.1 - 1.2e-07 31.7 16.1 2e-07 31.0 16.1 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 GAM22339.1 - 0.053 13.6 5.8 0.098 12.8 5.8 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3624 PF12292.8 GAM22339.1 - 0.38 11.2 6.0 0.62 10.5 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) DUF1451 PF07295.11 GAM22339.1 - 0.65 10.0 4.9 0.99 9.4 4.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain HEPN_Swt1 PF18731.1 GAM22340.1 - 0.018 15.4 0.1 0.018 15.4 0.1 2.9 2 1 0 2 2 2 0 Swt1-like HEPN TFIIA PF03153.13 GAM22340.1 - 0.02 14.9 26.8 0.026 14.6 26.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_20 PF00728.22 GAM22342.1 - 3.5e-81 273.3 1.1 4.4e-81 273.0 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAM22342.1 - 9.1e-18 65.2 0.3 6.4e-17 62.5 0.3 2.1 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAM22342.1 - 0.00015 22.6 0.0 0.00025 21.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Peptidase_M8 PF01457.16 GAM22343.1 - 3.4e-43 148.2 3.3 1.4e-42 146.1 3.3 1.8 1 1 0 1 1 1 1 Leishmanolysin Coatomer_WDAD PF04053.14 GAM22344.1 - 2.4e-06 26.9 0.5 0.05 12.6 0.1 3.1 3 0 0 3 3 3 2 Coatomer WD associated region WD40 PF00400.32 GAM22344.1 - 0.00081 20.2 5.0 0.019 15.8 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat FlxA PF14282.6 GAM22344.1 - 0.053 13.5 0.4 0.15 12.1 0.4 1.7 1 0 0 1 1 1 0 FlxA-like protein SF3A2 PF16835.5 GAM22345.1 - 1.2e-33 115.4 0.0 1.8e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 GAM22345.1 - 4.3e-06 26.9 0.9 7.3e-06 26.2 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 GAM22345.1 - 0.00017 21.6 0.1 0.00025 20.9 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Big_10 PF17964.1 GAM22346.1 - 0.023 14.7 1.2 0.05 13.6 1.2 1.5 1 0 0 1 1 1 0 Bacterial Ig domain IF4E PF01652.18 GAM22347.1 - 2.5e-38 131.4 1.5 3.6e-38 130.8 1.0 1.4 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Caldesmon PF02029.15 GAM22347.1 - 0.0046 15.8 3.9 0.0064 15.3 3.9 1.2 1 0 0 1 1 1 1 Caldesmon AAA_32 PF13654.6 GAM22347.1 - 0.46 9.2 9.2 0.57 8.9 3.6 2.4 3 0 0 3 3 3 0 AAA domain TcpS PF17456.2 GAM22347.1 - 1 9.4 10.0 0.059 13.4 4.7 1.7 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S Bac_small_YrzI PF09501.10 GAM22347.1 - 2.8 8.1 11.2 2.9 8.1 5.1 3.0 1 1 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Acyltransferase PF01553.21 GAM22349.1 - 1.4e-05 24.7 0.2 0.0001 21.9 0.1 2.2 2 1 0 2 2 2 1 Acyltransferase RTTN_N PF14726.6 GAM22350.1 - 0.32 11.8 2.5 1.3e+02 3.5 0.0 5.1 6 0 0 6 6 6 0 Rotatin, an armadillo repeat protein, centriole functioning LapA_dom PF06305.11 GAM22351.1 - 3.3 7.6 4.7 3.1 7.7 0.2 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Glyco_hydro_14 PF01373.17 GAM22352.1 - 1.9e-114 382.8 1.1 2.2e-114 382.6 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 UPF0029 PF01205.19 GAM22353.1 - 2.2e-30 105.1 1.3 3.5e-30 104.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 GAM22353.1 - 8.1e-14 51.9 1.6 3.3e-13 50.0 0.7 2.3 2 1 0 2 2 2 1 RWD domain Ribosomal_L39 PF00832.20 GAM22354.1 - 8.7e-23 79.7 10.6 1e-22 79.5 10.6 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Sec10 PF07393.11 GAM22355.1 - 3.6e-102 343.0 31.7 6.9e-53 180.1 10.6 2.9 2 1 1 3 3 3 2 Exocyst complex component Sec10 DUF1664 PF07889.12 GAM22355.1 - 0.0013 18.8 4.8 0.0018 18.3 0.7 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) IFT20 PF14931.6 GAM22355.1 - 0.061 13.5 7.5 0.42 10.8 1.2 3.1 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 ArdA PF07275.11 GAM22355.1 - 0.22 12.1 0.9 5.3 7.6 0.1 2.9 2 1 1 3 3 3 0 Antirestriction protein (ArdA) DUF948 PF06103.11 GAM22355.1 - 0.7 10.2 4.1 11 6.4 0.5 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Sec7_N PF12783.7 GAM22355.1 - 1.2 9.0 7.6 1.1 9.2 1.4 2.9 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal FliJ PF02050.16 GAM22355.1 - 1.5 9.0 9.3 7.8 6.7 6.6 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein Syntaxin-6_N PF09177.11 GAM22355.1 - 2.3 8.8 11.4 0.31 11.6 0.8 3.9 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Laminin_II PF06009.12 GAM22355.1 - 8.1 6.5 8.6 2.9 7.9 1.3 2.8 1 1 1 2 2 2 0 Laminin Domain II DUF16 PF01519.16 GAM22355.1 - 9.4 6.8 8.3 2.5 8.6 1.1 3.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 WD40 PF00400.32 GAM22356.1 - 1e-16 61.0 9.8 4.1e-06 27.4 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM22356.1 - 5.7e-09 36.2 0.5 0.0045 17.3 0.1 4.3 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GAM22356.1 - 0.001 18.7 0.2 0.029 13.9 0.1 2.6 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.8 GAM22356.1 - 0.0064 15.2 2.5 0.27 9.8 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 CCDC74_C PF14917.6 GAM22356.1 - 0.015 15.8 4.2 0.027 15.0 4.2 1.3 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal GreA_GreB_N PF03449.15 GAM22356.1 - 0.18 12.0 2.1 0.59 10.3 2.1 1.8 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal TMP_2 PF06791.13 GAM22356.1 - 0.49 10.0 3.1 0.35 10.5 0.6 1.9 2 0 0 2 2 2 0 Prophage tail length tape measure protein CENP-H PF05837.12 GAM22356.1 - 0.59 10.6 7.7 0.11 12.9 3.7 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF1690 PF07956.11 GAM22356.1 - 0.62 10.5 4.7 1.2 9.5 4.7 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) PQQ_3 PF13570.6 GAM22356.1 - 1.2 9.7 7.8 4.1 8.0 0.1 4.3 6 0 0 6 6 5 0 PQQ-like domain DivIC PF04977.15 GAM22356.1 - 1.8 8.4 4.0 1.6 8.5 1.0 2.3 2 0 0 2 2 2 0 Septum formation initiator KIX_2 PF16987.5 GAM22358.1 - 3.3e-07 30.2 2.0 3.3e-07 30.2 2.0 2.9 3 0 0 3 3 3 1 KIX domain Med15 PF09606.10 GAM22358.1 - 6.8e-07 28.4 13.3 2.6e-05 23.2 7.9 4.1 2 1 2 4 4 4 2 ARC105 or Med15 subunit of Mediator complex non-fungal Spherulin4 PF12138.8 GAM22358.1 - 0.39 10.3 3.6 0.56 9.8 1.5 2.1 2 1 0 2 2 2 0 Spherulation-specific family 4 DUF1129 PF06570.11 GAM22358.1 - 1 8.8 3.9 2 7.9 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) eIF-3_zeta PF05091.12 GAM22358.1 - 4.6 6.1 16.2 8.6 5.2 16.2 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 GAM22358.1 - 7.5 5.2 13.2 14 4.3 13.2 1.4 1 0 0 1 1 1 0 Presenilin DUF2201 PF09967.9 GAM22359.1 - 5.1e-05 23.4 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 VWA-like domain (DUF2201) VWA_CoxE PF05762.14 GAM22359.1 - 0.00066 19.1 0.1 0.0052 16.2 0.0 2.3 2 1 0 2 2 2 1 VWA domain containing CoxE-like protein VWA PF00092.28 GAM22359.1 - 0.001 19.4 0.1 0.092 13.0 0.1 2.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Tfb5 PF06331.12 GAM22360.1 - 3.7e-14 52.5 0.1 4.4e-14 52.2 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Ank_2 PF12796.7 GAM22361.1 - 8e-11 42.4 5.4 7.6e-05 23.2 0.1 5.6 3 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM22361.1 - 0.00011 22.4 9.8 7.5 7.5 0.0 7.8 11 0 0 11 11 11 2 Ankyrin repeat Ank_4 PF13637.6 GAM22361.1 - 0.00033 21.1 9.5 0.084 13.5 0.0 6.5 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM22361.1 - 0.004 17.4 3.1 7.9 6.9 0.1 5.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 GAM22361.1 - 0.27 11.2 26.3 1.1 9.3 3.7 6.5 4 3 1 6 6 6 0 Domain of unknown function (DUF3447) Ank PF00023.30 GAM22361.1 - 2.7 8.6 4.7 43 4.8 0.0 4.8 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 GAM22362.1 - 4.4e-09 36.8 10.4 0.001 19.6 0.1 5.2 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM22362.1 - 1.5e-07 31.8 4.0 0.084 13.5 0.0 7.5 6 2 4 10 10 10 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM22362.1 - 4.3e-07 29.7 6.0 11 7.0 0.1 9.0 10 0 0 10 10 10 1 Ankyrin repeat DUF3447 PF11929.8 GAM22362.1 - 0.0028 17.6 7.6 0.11 12.5 0.6 4.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.6 GAM22362.1 - 0.053 13.9 1.9 39 4.7 0.3 4.4 3 2 2 5 5 5 0 Ankyrin repeats (many copies) PAP2 PF01569.21 GAM22363.1 - 8e-25 87.2 1.3 8e-25 87.2 1.3 1.9 2 1 0 2 2 2 1 PAP2 superfamily FtsX PF02687.21 GAM22363.1 - 0.12 12.8 1.9 1.1 9.8 0.1 2.5 2 1 0 2 2 2 0 FtsX-like permease family PfkB PF00294.24 GAM22364.1 - 1e-13 51.3 0.0 6.8e-11 42.0 0.0 2.3 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Dus PF01207.17 GAM22365.1 - 2.9e-71 240.1 0.0 3.8e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Secretin_N_2 PF07655.13 GAM22365.1 - 4.4 7.9 11.3 10 6.8 10.8 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain PH_3 PF14593.6 GAM22366.1 - 2.7e-12 46.7 0.1 4.1e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 PH domain PH PF00169.29 GAM22366.1 - 1.2e-11 45.1 0.0 1.6e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM22366.1 - 0.0003 21.2 0.6 0.0053 17.2 0.6 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAM22366.1 - 0.0041 17.4 0.0 0.0056 16.9 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 GAM22366.1 - 0.13 12.6 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain LRR_6 PF13516.6 GAM22368.1 - 7.6e-07 28.7 33.7 4.3 7.6 0.1 10.6 11 0 0 11 11 11 6 Leucine Rich repeat LRR_1 PF00560.33 GAM22368.1 - 8e-05 22.7 34.4 10 7.1 0.9 12.2 14 0 0 14 14 14 1 Leucine Rich Repeat LRR_4 PF12799.7 GAM22368.1 - 8.7e-05 22.8 38.8 0.0034 17.8 0.4 8.8 5 2 5 10 10 10 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM22368.1 - 0.0014 18.3 26.2 0.01 15.6 0.4 7.2 6 3 0 6 6 6 3 Leucine rich repeat Proteasome PF00227.26 GAM22369.1 - 3.4e-33 114.7 0.0 4.4e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Mito_carr PF00153.27 GAM22370.1 - 1.4e-57 191.6 3.1 4.6e-24 84.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S9 PF00380.19 GAM22370.1 - 0.012 16.2 0.2 0.048 14.2 0.0 2.0 1 1 1 2 2 2 0 Ribosomal protein S9/S16 RAP1 PF07218.11 GAM22370.1 - 0.11 10.8 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BSD PF03909.17 GAM22371.1 - 3.1e-05 23.9 0.0 7.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 BSD domain ERCC3_RAD25_C PF16203.5 GAM22372.1 - 3.2e-116 386.8 0.1 5.1e-116 386.2 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 GAM22372.1 - 3.6e-38 130.6 0.0 7.2e-38 129.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM22372.1 - 2e-13 50.7 0.0 5e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM22372.1 - 6.2e-11 42.6 0.7 8.7e-10 38.9 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 GAM22372.1 - 9.2e-09 34.5 0.0 3e-08 32.8 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 GAM22372.1 - 0.0083 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Phosducin PF02114.16 GAM22373.1 - 6.7e-07 28.5 0.6 7.2e-07 28.4 0.6 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 GAM22373.1 - 1.4e-06 28.2 0.1 2.3e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Peptidase_M4 PF01447.18 GAM22373.1 - 0.045 14.2 0.1 0.068 13.7 0.1 1.2 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain Thioredoxin_2 PF13098.6 GAM22373.1 - 0.047 14.1 0.5 0.18 12.2 0.5 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain DarA_N PF18788.1 GAM22373.1 - 0.066 13.3 1.7 0.28 11.3 0.7 2.1 2 0 0 2 2 2 0 Defence against restriction A N-terminal Fasciclin PF02469.22 GAM22373.1 - 0.07 13.3 0.4 0.15 12.3 0.2 1.6 2 1 0 2 2 2 0 Fasciclin domain Mito_carr PF00153.27 GAM22374.1 - 3e-53 177.7 0.6 2.3e-22 78.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 GAM22374.1 - 0.034 14.5 2.0 10 6.5 0.0 3.5 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Iso_dh PF00180.20 GAM22375.1 - 4e-87 292.6 1.8 5e-87 292.3 1.8 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Acetyltransf_14 PF03421.16 GAM22375.1 - 0.067 13.2 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase IQ PF00612.27 GAM22377.1 - 1e-08 34.2 8.9 6.4e-05 22.4 4.0 2.3 2 0 0 2 2 2 2 IQ calmodulin-binding motif Rhamno_transf PF11316.8 GAM22377.1 - 0.04 13.3 2.0 0.058 12.8 2.0 1.2 1 0 0 1 1 1 0 Putative rhamnosyl transferase Rsc14 PF08586.10 GAM22377.1 - 0.29 11.9 6.2 1.1 10.1 0.3 2.3 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit E1-E2_ATPase PF00122.20 GAM22379.1 - 6.7e-21 74.6 0.0 1.6e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 GAM22379.1 - 1.5e-19 71.2 0.1 1.6e-09 38.4 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM22379.1 - 3.8e-05 23.7 0.0 0.00013 22.0 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) NOZZLE PF08744.10 GAM22379.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Plant transcription factor NOZZLE Hydrolase_3 PF08282.12 GAM22379.1 - 0.0018 18.1 6.0 0.028 14.1 0.1 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAM22379.1 - 0.02 15.0 0.4 4.9 7.2 0.1 3.3 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF4083 PF13314.6 GAM22379.1 - 0.26 11.3 2.1 1 9.3 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Guanylate_cyc PF00211.20 GAM22380.1 - 3.5e-22 78.9 1.1 1.6e-11 44.2 0.0 2.8 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 GAM22380.1 - 1.7e-12 48.0 0.0 4.3e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM22380.1 - 0.00028 21.2 0.0 0.0025 18.1 0.0 2.6 1 1 0 2 2 2 1 AAA domain TPR_12 PF13424.6 GAM22380.1 - 0.0009 19.5 1.5 0.21 11.9 0.0 4.0 4 1 2 6 6 6 2 Tetratricopeptide repeat Mucin PF01456.17 GAM22380.1 - 2.9 7.9 8.7 1.1 9.3 4.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Med11 PF10280.9 GAM22382.1 - 0.0039 17.6 0.1 0.011 16.2 0.1 1.8 1 0 0 1 1 1 1 Mediator complex protein TFIIA PF03153.13 GAM22382.1 - 0.45 10.5 9.2 0.67 9.9 9.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TSA PF03249.13 GAM22382.1 - 1.7 7.4 4.5 2.7 6.7 4.5 1.3 1 0 0 1 1 1 0 Type specific antigen DUF3439 PF11921.8 GAM22382.1 - 1.8 8.6 7.4 5.7 6.9 4.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SUIM_assoc PF16619.5 GAM22382.1 - 3.2 7.9 18.2 0.41 10.7 7.8 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Kelch_4 PF13418.6 GAM22383.1 - 4.2e-44 148.3 10.4 4.4e-09 36.2 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM22383.1 - 8e-37 124.8 10.7 7e-09 35.8 0.2 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM22383.1 - 1.6e-36 123.4 14.8 7.9e-10 38.7 0.0 6.3 3 2 3 6 6 6 5 Kelch motif Kelch_5 PF13854.6 GAM22383.1 - 2e-34 117.0 13.3 4.4e-08 32.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 GAM22383.1 - 3.2e-34 116.3 12.5 4e-07 29.5 0.0 6.4 6 1 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAM22383.1 - 5e-29 99.2 5.0 2.9e-05 23.9 0.1 5.9 6 0 0 6 6 6 5 Kelch motif K-box PF01486.17 GAM22383.1 - 0.0049 17.0 11.4 0.0049 17.0 11.4 3.0 3 0 0 3 3 3 1 K-box region Ank_2 PF12796.7 GAM22384.1 - 4.4e-05 24.0 0.7 0.35 11.5 0.1 3.9 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM22384.1 - 0.0088 16.5 0.0 57 4.8 0.0 5.4 6 0 0 6 6 6 0 Ankyrin repeat Ank_4 PF13637.6 GAM22384.1 - 0.015 15.9 0.4 18 6.1 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Orbi_VP3 PF01700.16 GAM22384.1 - 0.13 10.2 0.5 0.3 9.0 0.0 1.7 2 0 0 2 2 2 0 Orbivirus VP3 (T2) protein Ras PF00071.22 GAM22385.1 - 2.4e-18 66.2 0.0 9.6e-17 61.0 0.0 2.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAM22385.1 - 3.4e-13 49.9 0.0 3.3e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM22385.1 - 3.6e-07 29.8 0.1 9.5e-06 25.2 0.1 2.2 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM22385.1 - 7.2e-06 26.1 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM22385.1 - 0.031 14.2 0.0 0.72 9.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 GAM22385.1 - 0.035 13.6 0.1 0.052 13.1 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 GAM22385.1 - 0.045 13.8 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Dynamin family YIF1 PF03878.15 GAM22386.1 - 4.9e-79 265.2 4.9 4.9e-79 265.2 4.9 1.4 2 0 0 2 2 2 1 YIF1 Yip1 PF04893.17 GAM22386.1 - 3.9e-05 23.4 6.5 6.8e-05 22.7 6.5 1.4 1 0 0 1 1 1 1 Yip1 domain ubiquitin PF00240.23 GAM22387.1 - 2.1e-27 94.6 0.2 2.3e-27 94.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM22387.1 - 4.3e-17 61.7 0.2 4.7e-17 61.6 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAM22387.1 - 1.1e-05 25.8 0.1 3.3e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAM22387.1 - 0.00017 21.4 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain VWA_2 PF13519.6 GAM22388.1 - 3.9e-07 30.7 0.0 1.2e-06 29.2 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Ras PF00071.22 GAM22388.1 - 6.7e-07 29.0 0.1 0.0002 21.0 0.0 2.6 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAM22388.1 - 0.043 14.0 0.0 2.2 8.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Phage_C PF12025.8 GAM22389.1 - 0.13 12.1 0.1 9.4 6.2 0.0 2.6 2 1 0 2 2 2 0 Phage protein C PQ-loop PF04193.14 GAM22390.1 - 0.051 13.4 0.3 0.051 13.4 0.3 2.4 3 0 0 3 3 3 0 PQ loop repeat ECF_trnsprt PF12822.7 GAM22390.1 - 6.9 6.7 12.1 0.26 11.4 3.8 2.5 3 0 0 3 3 3 0 ECF transporter, substrate-specific component FAM75 PF14650.6 GAM22391.1 - 0.41 10.2 1.9 0.64 9.5 1.9 1.2 1 0 0 1 1 1 0 FAM75 family EGF_2 PF07974.13 GAM22392.1 - 0.031 14.7 17.7 0.075 13.4 17.7 1.7 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 GAM22392.1 - 0.28 11.9 9.3 0.9 10.3 9.3 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Methyltransf_21 PF05050.12 GAM22393.1 - 0.044 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase FkbM domain EGF_2 PF07974.13 GAM22393.1 - 0.19 12.1 15.9 0.44 11.0 15.9 1.6 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 GAM22393.1 - 0.56 10.6 10.1 1.3 9.4 10.1 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 GAM22393.1 - 6.9 6.8 12.5 1 9.5 8.5 1.8 2 0 0 2 2 2 0 Tenascin EGF domain FA_hydroxylase PF04116.13 GAM22394.1 - 3.1e-24 85.8 9.3 3.1e-24 85.8 9.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily EB PF01683.18 GAM22395.1 - 0.0041 17.4 4.4 0.011 16.1 4.4 1.6 1 0 0 1 1 1 1 EB module I-EGF_1 PF18372.1 GAM22395.1 - 0.15 12.2 7.8 0.31 11.2 7.8 1.5 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 GAM22395.1 - 0.15 12.4 17.3 0.33 11.4 17.3 1.5 1 0 0 1 1 1 0 EGF-like domain TMEM154 PF15102.6 GAM22395.1 - 7.7 6.4 6.7 0.63 9.9 0.1 2.4 3 0 0 3 3 3 0 TMEM154 protein family EB PF01683.18 GAM22396.1 - 0.00069 19.9 4.7 0.0016 18.7 4.7 1.6 1 0 0 1 1 1 1 EB module TMEM154 PF15102.6 GAM22396.1 - 0.0019 18.1 1.3 0.0056 16.6 1.3 1.7 1 0 0 1 1 1 1 TMEM154 protein family EGF_2 PF07974.13 GAM22396.1 - 0.0092 16.3 19.8 0.028 14.8 19.8 1.8 1 0 0 1 1 1 1 EGF-like domain Sigma_reg_N PF13800.6 GAM22396.1 - 3.2 8.1 5.8 9 6.7 2.2 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal I-EGF_1 PF18372.1 GAM22396.1 - 5.9 7.1 16.0 1.3 9.1 10.1 2.4 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 DUF4052 PF13261.6 GAM22397.1 - 0.15 11.9 1.7 0.12 12.2 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4052) EB PF01683.18 GAM22398.1 - 0.00014 22.1 4.1 0.0003 21.0 4.1 1.5 1 0 0 1 1 1 1 EB module EGF_2 PF07974.13 GAM22398.1 - 0.5 10.8 18.7 1.3 9.4 18.7 1.8 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 GAM22398.1 - 0.57 10.9 6.9 1.9 9.2 6.9 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF CotE PF10628.9 GAM22398.1 - 0.66 9.6 4.8 0.2 11.3 0.5 2.1 2 0 0 2 2 2 0 Outer spore coat protein E (CotE) EGF PF00008.27 GAM22398.1 - 3.2 8.1 10.3 11 6.4 10.3 1.9 1 0 0 1 1 1 0 EGF-like domain Ribosomal_L22e PF01776.17 GAM22399.1 - 2.6e-18 66.4 0.1 3e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Snf7 PF03357.21 GAM22400.1 - 1.5e-28 99.6 26.7 1.7e-28 99.4 26.7 1.1 1 0 0 1 1 1 1 Snf7 PIEZO PF15917.5 GAM22400.1 - 0.097 12.1 12.8 0.032 13.7 10.1 1.5 1 1 0 1 1 1 0 Piezo DUF1722 PF08349.11 GAM22400.1 - 0.19 12.0 5.3 0.1 12.9 2.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) Snapin_Pallidin PF14712.6 GAM22400.1 - 0.63 10.5 15.5 0.095 13.1 8.9 2.6 1 1 2 3 3 3 0 Snapin/Pallidin Alkyl_sulf_dimr PF14863.6 GAM22400.1 - 1.6 9.2 11.9 4.5 7.7 3.3 2.3 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation CCDC84 PF14968.6 GAM22400.1 - 2.2 7.8 10.9 2.8 7.5 10.9 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 YlqD PF11068.8 GAM22400.1 - 2.3 8.6 20.3 0.16 12.3 10.2 2.2 1 1 1 2 2 2 0 YlqD protein Prefoldin_2 PF01920.20 GAM22400.1 - 2.4 8.1 21.4 4.9 7.1 5.6 3.1 1 1 2 3 3 3 0 Prefoldin subunit DUF3371 PF11851.8 GAM22400.1 - 5.7 8.0 11.3 14 6.8 11.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3371) Peroxin-13_N PF04088.13 GAM22401.1 - 4.5e-21 75.6 2.6 4.5e-21 75.6 2.6 2.6 2 1 1 3 3 3 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 GAM22401.1 - 1.7e-14 53.2 0.0 3.8e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM22401.1 - 5.9e-14 51.4 0.0 1.1e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM22401.1 - 1.4e-13 50.5 0.0 2.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Coilin_N PF15862.5 GAM22401.1 - 0.009 15.8 0.0 0.087 12.6 0.0 2.1 1 1 1 2 2 2 1 Coilin N-terminus PRP21_like_P PF12230.8 GAM22402.1 - 4.2e-41 141.2 19.1 1.9e-40 139.0 19.1 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 GAM22402.1 - 5.5e-35 119.1 4.2 3.1e-17 62.3 0.1 2.5 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 GAM22402.1 - 7e-10 38.5 0.6 1.5e-09 37.5 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 GAM22402.1 - 0.00048 20.5 0.6 0.0016 18.8 0.6 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain zf_UBZ PF18439.1 GAM22402.1 - 0.0019 17.7 1.0 0.0047 16.5 1.0 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger UN_NPL4 PF11543.8 GAM22402.1 - 0.14 12.7 0.1 0.39 11.2 0.1 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-Di19 PF05605.12 GAM22402.1 - 0.2 12.0 0.2 0.38 11.1 0.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Mito_carr PF00153.27 GAM22403.1 - 4.2e-65 215.7 3.8 3.3e-21 75.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UPF0154 PF03672.13 GAM22403.1 - 0.014 15.4 0.2 0.045 13.8 0.2 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Serine_protease PF18405.1 GAM22403.1 - 0.015 14.5 3.7 1.9 7.6 0.0 3.4 2 1 2 4 4 4 0 Gammaproteobacterial serine protease DUF3899 PF13038.6 GAM22403.1 - 0.13 12.8 0.6 17 6.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) ATG11 PF10377.9 GAM22404.1 - 1.6e-09 37.9 0.1 1.6e-09 37.9 0.1 4.8 4 0 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.12 GAM22404.1 - 0.0001 21.6 2.2 0.0001 21.6 2.2 9.5 2 2 1 5 5 5 2 Autophagy protein Apg17 Tis11B_N PF04553.12 GAM22404.1 - 0.034 14.7 2.7 0.42 11.2 0.4 3.2 2 0 0 2 2 2 0 Tis11B like protein, N terminus ATG_C PF09333.11 GAM22404.1 - 1.2 9.6 4.1 56 4.2 0.2 3.9 5 0 0 5 5 5 0 Autophagy-related protein C terminal domain Histone PF00125.24 GAM22405.1 - 3.5e-11 43.6 0.1 6.1e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAM22405.1 - 1.8e-09 37.7 0.2 2.9e-08 33.9 0.0 2.2 1 1 2 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone_H2A_C PF16211.5 GAM22405.1 - 4.5e-06 26.3 0.7 1.6e-05 24.5 0.7 2.0 1 1 0 1 1 1 1 C-terminus of histone H2A Dmrt1 PF12374.8 GAM22405.1 - 0.096 13.1 1.2 0.096 13.1 1.2 1.8 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 TMCO5 PF14992.6 GAM22406.1 - 0.3 10.6 1.7 0.56 9.7 1.7 1.5 1 0 0 1 1 1 0 TMCO5 family Metal_hydrol PF10118.9 GAM22406.1 - 2.5 7.8 4.4 0.56 9.9 0.3 1.9 2 0 0 2 2 2 0 Predicted metal-dependent hydrolase DUF3391 PF11871.8 GAM22407.1 - 0.075 13.6 1.2 0.19 12.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) AJAP1_PANP_C PF15298.6 GAM22407.1 - 0.94 9.7 16.7 2.3 8.4 12.9 2.3 2 0 0 2 2 2 0 AJAP1/PANP C-terminus CPSF100_C PF13299.6 GAM22407.1 - 6.8 6.9 8.5 2.9 8.0 1.0 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Thiolase_N PF00108.23 GAM22408.1 - 2.8e-81 272.7 3.1 3.8e-81 272.3 3.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM22408.1 - 4.2e-47 158.8 0.8 9.6e-47 157.7 0.8 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAM22408.1 - 0.001 18.7 0.1 0.0029 17.2 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAM22408.1 - 0.0093 15.8 0.6 1.6 8.7 0.1 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CopK PF11525.8 GAM22408.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Copper resistance protein K Myosin_N PF02736.19 GAM22408.1 - 0.19 11.6 1.8 0.38 10.6 1.8 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain RasGEF PF00617.19 GAM22409.1 - 1.9e-54 184.5 0.3 6.4e-54 182.8 0.3 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM22409.1 - 7.2e-20 71.2 0.6 7.2e-20 71.2 0.6 3.4 3 0 0 3 3 3 1 RasGEF N-terminal motif HNF-1_N PF04814.13 GAM22410.1 - 0.11 13.1 2.6 0.15 12.6 2.6 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus FSA_C PF10479.9 GAM22410.1 - 0.14 10.3 6.4 0.16 10.1 6.4 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Allexi_40kDa PF05549.11 GAM22410.1 - 0.19 11.2 6.3 0.27 10.7 5.4 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF3439 PF11921.8 GAM22410.1 - 0.39 10.7 6.4 0.62 10.0 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TetR_C_8 PF14278.6 GAM22411.1 - 0.13 12.4 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region ABC2_membrane_3 PF12698.7 GAM22412.1 - 1.9e-56 191.7 56.4 4e-31 108.4 23.2 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 GAM22412.1 - 1.6e-47 161.5 0.0 6.6e-23 81.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAM22412.1 - 3.4e-16 60.0 0.5 7.9e-07 29.2 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM22412.1 - 0.00071 19.1 0.0 8.9 5.7 0.0 3.6 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 GAM22412.1 - 0.0039 17.4 0.0 0.32 11.3 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 GAM22412.1 - 0.019 14.7 0.2 0.86 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 GAM22412.1 - 0.041 13.2 0.1 10 5.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin UCR_6-4kD PF08997.10 GAM22412.1 - 0.057 13.4 1.3 0.48 10.4 0.9 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein AAA_23 PF13476.6 GAM22412.1 - 0.061 13.8 1.3 3.5 8.1 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAM22412.1 - 0.077 12.7 1.6 6.9 6.5 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC2_membrane PF01061.24 GAM22412.1 - 0.08 12.3 44.4 0.0066 15.9 16.2 3.5 3 1 1 4 4 4 0 ABC-2 type transporter RsgA_GTPase PF03193.16 GAM22412.1 - 0.11 12.4 0.7 7.2 6.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase ABC2_membrane_2 PF12679.7 GAM22412.1 - 0.27 10.5 31.2 1 8.6 7.0 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein SRP54 PF00448.22 GAM22412.1 - 0.6 9.7 5.6 0.67 9.6 0.4 2.6 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF2070 PF09843.9 GAM22412.1 - 9.4 4.4 27.6 0.068 11.5 11.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Pro-kuma_activ PF09286.11 GAM22413.1 - 1e-21 77.7 0.1 2.4e-21 76.5 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM22413.1 - 1.4e-07 31.1 1.0 2.4e-07 30.3 1.0 1.2 1 0 0 1 1 1 1 Subtilase family DUF2486 PF10667.9 GAM22414.1 - 3.1 7.9 9.1 0.16 12.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) ABC_membrane PF00664.23 GAM22415.1 - 4.7e-56 190.4 39.4 7.9e-31 107.7 13.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM22415.1 - 2.1e-46 157.8 0.2 2.7e-27 96.0 0.0 3.2 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.19 GAM22415.1 - 1.3e-08 34.5 1.3 0.0019 17.7 0.1 4.0 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAM22415.1 - 0.00045 20.2 0.1 0.15 12.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAM22415.1 - 0.0013 18.8 3.7 0.92 9.6 0.1 3.5 4 0 0 4 4 4 2 50S ribosome-binding GTPase AAA_25 PF13481.6 GAM22415.1 - 0.002 17.7 0.0 0.15 11.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 GAM22415.1 - 0.0031 17.4 1.7 15 5.3 0.1 3.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM22415.1 - 0.026 14.3 8.8 1.8 8.3 0.0 4.1 5 0 0 5 5 5 0 P-loop containing region of AAA domain AAA_7 PF12775.7 GAM22415.1 - 0.037 13.5 0.9 8.1 5.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 GAM22415.1 - 0.041 14.3 0.8 6.8 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 GAM22415.1 - 0.063 12.2 1.8 4.9 6.0 0.2 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 GAM22415.1 - 0.085 13.3 4.8 2.2 8.8 0.2 3.2 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 GAM22415.1 - 0.096 11.6 0.3 9.7 5.1 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 GAM22415.1 - 0.15 12.4 0.4 21 5.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAM22415.1 - 0.3 10.8 1.1 25 4.5 0.2 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 GAM22415.1 - 0.32 11.0 6.3 0.17 11.9 0.2 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 GAM22415.1 - 0.6 9.4 2.3 11 5.2 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin Ank_2 PF12796.7 GAM22416.1 - 1.3e-32 112.2 1.1 2.6e-09 37.5 0.0 6.4 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM22416.1 - 1.1e-25 89.6 1.9 3.4e-07 30.7 0.0 7.3 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM22416.1 - 4.4e-25 87.4 3.5 7.2e-07 29.4 0.0 7.3 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM22416.1 - 3.5e-23 79.2 5.5 0.0011 19.3 0.0 10.1 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 GAM22416.1 - 2.7e-22 78.2 8.3 0.00062 20.1 0.2 9.2 9 1 0 9 9 9 6 Ankyrin repeat Nanovirus_C8 PF05629.11 GAM22416.1 - 0.26 11.4 0.7 1.1 9.4 0.0 2.2 3 0 0 3 3 3 0 Nanovirus component 8 (C8) protein FNIP PF05725.12 GAM22417.1 - 8.7e-59 195.5 26.1 1.8e-14 53.6 0.6 7.4 3 2 2 8 8 8 7 FNIP Repeat DUF1769 PF08588.10 GAM22417.1 - 0.028 14.6 0.3 25 5.2 0.0 3.8 5 1 1 6 6 6 0 Protein of unknown function (DUF1769) Terpene_synth PF01397.21 GAM22417.1 - 0.093 12.4 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain ComR_TPR PF18710.1 GAM22419.1 - 0.019 14.6 0.9 1.2 8.7 0.0 2.0 1 1 1 2 2 2 0 ComR tetratricopeptide DUF5388 PF17363.2 GAM22419.1 - 0.02 15.1 0.4 6.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5388) NAPRTase_N PF17767.1 GAM22419.1 - 0.061 13.7 1.2 0.28 11.6 0.3 2.3 1 1 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DNA_pol_B_2 PF03175.13 GAM22420.1 - 5.7e-07 28.8 1.1 8.5e-07 28.2 1.1 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral PPR_2 PF13041.6 GAM22420.1 - 0.079 13.2 0.2 0.59 10.4 0.0 2.4 2 0 0 2 2 2 0 PPR repeat family VCX_VCY PF15231.6 GAM22421.1 - 0.18 12.5 3.1 1.7 9.4 1.0 2.2 1 1 1 2 2 2 0 Variable charge X/Y family zf-RING_5 PF14634.6 GAM22422.1 - 0.019 14.9 2.0 0.028 14.4 1.2 1.7 2 0 0 2 2 2 0 zinc-RING finger domain RFXA_RFXANK_bdg PF15289.6 GAM22422.1 - 0.4 11.0 2.8 3.1 8.1 0.1 2.5 2 1 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain DAAD PF18752.1 GAM22424.1 - 1e-09 38.7 2.4 1.4e-09 38.2 2.4 1.3 1 0 0 1 1 1 1 Dictyosteliid AID/APOBEC-like Deaminase NAD1 PF18778.1 GAM22424.1 - 0.0021 18.2 0.3 0.0034 17.5 0.3 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 SNAD4 PF18750.1 GAM22424.1 - 0.0094 16.1 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 GAM22424.1 - 0.018 15.1 0.1 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 APOBEC2 Hema_esterase PF03996.15 GAM22425.1 - 0.075 12.8 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Hemagglutinin esterase SP_C-Propep PF08999.10 GAM22426.1 - 0.0003 20.5 1.7 0.00039 20.2 1.7 1.4 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide ABC_tran PF00005.27 GAM22430.1 - 4.2e-50 169.8 0.0 3.2e-25 89.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 GAM22430.1 - 1.3e-44 152.7 49.0 4.4e-24 85.2 22.7 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 GAM22430.1 - 2.7e-18 66.8 0.0 1e-06 28.8 0.0 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM22430.1 - 0.00099 18.8 2.8 0.058 13.1 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 GAM22430.1 - 0.0019 18.0 0.0 0.9 9.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain SRP54 PF00448.22 GAM22430.1 - 0.0021 17.7 0.5 1.1 8.8 0.1 2.6 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 GAM22430.1 - 0.029 14.6 0.0 2.3 8.5 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 GAM22430.1 - 0.034 14.6 5.1 2.5 8.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 GAM22430.1 - 0.042 13.7 0.5 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 GAM22430.1 - 0.058 13.3 0.0 3.5 7.5 0.0 2.6 3 0 0 3 3 3 0 Rad17 P-loop domain Oxysterol_BP PF01237.18 GAM22431.1 - 1.6e-51 175.3 2.3 1.5e-48 165.6 2.3 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein FNIP PF05725.12 GAM22432.1 - 1.2e-106 348.7 47.7 8.9e-14 51.4 2.3 13.5 7 4 7 15 15 15 15 FNIP Repeat HlyIII PF03006.20 GAM22433.1 - 5.4e-45 153.8 19.4 6.7e-45 153.5 19.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 GAM22433.1 - 0.024 14.7 0.0 0.1 12.7 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF962) PhoLip_ATPase_C PF16212.5 GAM22433.1 - 4.7 6.9 16.2 0.4 10.4 4.8 2.6 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal RWP-RK PF02042.15 GAM22434.1 - 9e-24 83.2 0.2 2.7e-23 81.7 0.0 2.0 2 0 0 2 2 2 1 RWP-RK domain HlyD_2 PF12700.7 GAM22434.1 - 0.16 10.6 5.2 0.25 10.0 5.2 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF4094 PF13334.6 GAM22434.1 - 1.1 9.7 8.3 19 5.8 2.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) NAT PF04768.13 GAM22435.1 - 4.6e-34 117.5 0.2 1.2e-33 116.2 0.0 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 GAM22435.1 - 1.1e-07 31.7 0.1 3e-07 30.3 0.1 1.8 1 1 0 1 1 1 1 Amino acid kinase family GCN5L1 PF06320.13 GAM22435.1 - 0.044 13.9 1.8 0.11 12.7 0.1 2.4 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF953 PF06110.11 GAM22436.1 - 1.3e-15 57.1 0.0 1.4e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 GAM22436.1 - 0.002 18.1 0.1 0.0036 17.3 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 GAM22436.1 - 0.014 15.2 0.2 0.025 14.3 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin Glyco_hydro_38N PF01074.22 GAM22437.1 - 1.5e-66 224.7 6.2 2.6e-66 224.0 6.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 GAM22437.1 - 3.1e-15 56.1 0.1 6.3e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 GAM22437.1 - 4.6e-06 26.9 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 GAM22437.1 - 5.9e-05 23.1 0.0 0.0002 21.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF3987 PF13148.6 GAM22437.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) GRAM PF02893.20 GAM22438.1 - 1.5e-06 28.1 0.0 3.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Cob_adeno_trans PF01923.18 GAM22438.1 - 0.34 11.0 4.1 0.28 11.3 1.5 1.9 2 0 0 2 2 2 0 Cobalamin adenosyltransferase ZapB PF06005.12 GAM22438.1 - 6 7.4 16.3 5.7 7.5 11.2 2.7 2 1 0 2 2 2 0 Cell division protein ZapB Alpha-amylase_C PF02806.18 GAM22439.1 - 8.9e-24 83.8 0.1 2.6e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 GAM22439.1 - 6.6e-17 61.6 0.1 1.5e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 GAM22439.1 - 1.9e-13 50.7 0.9 1.1e-12 48.3 0.2 2.4 1 1 1 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 GAM22439.1 - 0.098 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain RasGAP PF00616.19 GAM22440.1 - 6.8e-32 110.9 2.6 3e-19 69.6 0.1 4.0 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase DUF547 PF04784.14 GAM22440.1 - 3.1e-23 82.1 0.0 9.2e-23 80.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DUF5525 PF17663.1 GAM22442.1 - 0.29 9.1 3.8 0.49 8.4 3.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Neisseria_TspB PF05616.13 GAM22442.1 - 0.39 9.2 2.2 0.55 8.7 2.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DAG1 PF05454.11 GAM22443.1 - 0.014 14.8 1.8 0.015 14.7 1.8 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF2606 PF10794.9 GAM22443.1 - 0.17 11.6 0.2 0.24 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) DUF4407 PF14362.6 GAM22443.1 - 0.41 10.0 3.8 0.55 9.5 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) T3SS_needle_reg PF09025.10 GAM22444.1 - 0.0075 16.2 0.3 0.024 14.6 0.3 1.8 1 0 0 1 1 1 1 YopR, type III needle-polymerisation regulator Mucin PF01456.17 GAM22444.1 - 1.3 9.0 21.8 2.9 7.9 21.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein WRC PF08879.10 GAM22445.1 - 0.024 14.3 2.2 0.024 14.3 2.2 2.8 1 1 1 2 2 2 0 WRC DUF1936 PF09151.10 GAM22445.1 - 1.6 8.7 5.0 3.7 7.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) DNA_pol_B_2 PF03175.13 GAM22446.1 - 9.9e-06 24.7 0.6 4e-05 22.7 0.6 1.9 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF4449 PF14613.6 GAM22448.1 - 3.7e-06 27.1 4.7 8e-06 26.1 4.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) PALP PF00291.25 GAM22449.1 - 2.2e-66 224.3 0.0 4.8e-66 223.2 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 GAM22449.1 - 2e-17 63.4 0.0 1.3e-09 38.4 0.0 3.4 2 1 0 2 2 2 2 CBS domain Zn_clus PF00172.18 GAM22450.1 - 0.034 14.3 6.7 0.062 13.4 6.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_65m PF03632.15 GAM22451.1 - 3.1e-53 181.0 1.6 1e-44 153.0 2.3 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain DUF2152 PF10222.9 GAM22451.1 - 4e-12 45.3 0.0 1.5e-10 40.1 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2152) Glyco_hydro_63 PF03200.16 GAM22452.1 - 7.2e-162 539.6 7.5 6e-161 536.5 7.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 GAM22452.1 - 1.4e-50 172.5 1.8 2.8e-50 171.5 1.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain HHV-1_VABD PF16852.5 GAM22452.1 - 0.028 14.4 0.1 5.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Herpes viral adaptor-to-host cellular mRNA binding domain TRAM_LAG1_CLN8 PF03798.16 GAM22453.1 - 4.6e-36 124.4 34.6 4.6e-36 124.4 34.6 1.8 2 0 0 2 2 2 1 TLC domain Glft2_N PF17994.1 GAM22453.1 - 0.076 12.9 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 Galactofuranosyltransferase 2 N-terminal DUF4834 PF16118.5 GAM22453.1 - 0.1 13.6 0.2 0.1 13.6 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Podoplanin PF05808.11 GAM22453.1 - 0.41 10.7 2.3 0.61 10.2 2.3 1.2 1 0 0 1 1 1 0 Podoplanin TIG PF01833.24 GAM22454.1 - 1.2e-08 34.9 29.5 0.00012 22.1 2.7 4.8 4 2 2 6 6 6 3 IPT/TIG domain AbiJ_NTD4 PF18863.1 GAM22454.1 - 0.094 13.2 0.4 7.7 7.0 0.1 2.3 2 0 0 2 2 2 0 AbiJ N-terminal domain 4 EGF_2 PF07974.13 GAM22455.1 - 0.0021 18.4 11.3 0.0043 17.4 11.3 1.5 1 0 0 1 1 1 1 EGF-like domain DUF3040 PF11239.8 GAM22455.1 - 0.023 15.0 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) EB PF01683.18 GAM22455.1 - 0.4 11.0 6.8 0.91 9.9 6.8 1.5 1 0 0 1 1 1 0 EB module Par3_HAL_N_term PF12053.8 GAM22456.1 - 0.00077 19.6 0.0 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins 1-cysPrx_C PF10417.9 GAM22456.1 - 0.094 12.6 0.1 0.29 11.0 0.1 1.9 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin SNARE PF05739.19 GAM22457.1 - 1.8e-05 24.7 0.7 4.8e-05 23.3 0.7 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 GAM22457.1 - 0.00041 20.1 15.7 0.001 18.8 1.4 2.4 2 0 0 2 2 2 2 Syntaxin ZFYVE21_C PF16696.5 GAM22457.1 - 0.08 12.8 2.5 0.15 11.9 2.5 1.4 1 0 0 1 1 1 0 Zinc finger FYVE domain-containing protein 21 C-terminus Kinesin PF00225.23 GAM22458.1 - 3.4e-108 361.5 5.4 3.4e-108 361.5 5.4 3.0 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 GAM22458.1 - 5.5e-29 101.0 10.7 1.4e-28 99.7 0.1 3.6 3 0 0 3 3 3 2 Microtubule binding MMR_HSR1 PF01926.23 GAM22458.1 - 0.019 15.0 0.3 0.82 9.8 0.0 3.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Response_reg PF00072.24 GAM22459.1 - 2.3e-21 76.0 0.1 2.3e-21 76.0 0.1 1.4 2 0 0 2 2 2 1 Response regulator receiver domain Med3 PF11593.8 GAM22459.1 - 0.0037 16.5 1.0 0.0037 16.5 1.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Cyclin PF08613.11 GAM22460.1 - 0.0045 17.4 3.6 0.014 15.8 3.6 1.9 1 1 0 1 1 1 1 Cyclin CDT1 PF08839.11 GAM22460.1 - 0.085 13.1 0.3 0.11 12.8 0.3 1.1 1 0 0 1 1 1 0 DNA replication factor CDT1 like Abhydrolase_1 PF00561.20 GAM22461.1 - 3.3e-08 33.5 0.1 6.9e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold PIGA PF08288.12 GAM22461.1 - 0.016 15.8 0.0 0.043 14.4 0.0 1.7 1 0 0 1 1 1 0 PIGA (GPI anchor biosynthesis) RAM PF15320.6 GAM22461.1 - 6.9 7.3 7.1 15 6.3 7.1 1.5 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Pro_isomerase PF00160.21 GAM22462.1 - 2.2e-48 164.5 1.9 2.6e-48 164.3 1.9 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HemN_C PF06969.16 GAM22463.1 - 6e-09 35.8 0.1 1.1e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 HemN C-terminal domain Radical_SAM PF04055.21 GAM22463.1 - 8.5e-09 36.0 0.0 1.7e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily TAXi_N PF14543.6 GAM22464.1 - 8.4e-15 55.5 1.7 8.4e-15 55.5 1.7 2.6 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp PF00026.23 GAM22464.1 - 5.6e-13 49.0 3.0 6.4e-12 45.5 3.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAM22464.1 - 3.1e-10 40.1 0.0 1e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal CBM49 PF09478.10 GAM22464.1 - 1.5e-08 34.8 2.7 0.00046 20.4 0.3 2.6 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 gag-asp_proteas PF13975.6 GAM22464.1 - 0.018 15.6 0.1 5.9 7.5 0.0 3.6 2 2 0 2 2 2 0 gag-polyprotein putative aspartyl protease Response_reg PF00072.24 GAM22465.1 - 8.1e-19 67.9 0.0 2.4e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain DDE_Tnp_1_7 PF13843.6 GAM22466.1 - 6.6e-05 22.4 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 TFIIA PF03153.13 GAM22467.1 - 1.8 8.5 17.2 2 8.3 17.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VPS9 PF02204.18 GAM22469.1 - 1.6e-07 31.5 0.0 3.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PA14 PF07691.12 GAM22470.1 - 5.3e-09 36.0 0.1 9.4e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 GAM22470.1 - 0.0021 17.9 6.7 0.0021 17.9 6.7 13.8 14 2 0 14 14 14 6 Dictyostelium (slime mold) repeat zf-B_box PF00643.24 GAM22472.1 - 0.023 14.8 1.6 0.093 12.9 1.6 2.0 1 0 0 1 1 1 0 B-box zinc finger FliT PF05400.13 GAM22472.1 - 0.16 12.8 1.1 1.1 10.2 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein FliT GLE1 PF07817.13 GAM22472.1 - 3.4 6.8 10.2 0.4 9.9 4.9 2.0 2 0 0 2 2 2 0 GLE1-like protein Velvet PF11754.8 GAM22472.1 - 5.9 6.8 8.1 0.85 9.5 4.2 1.5 2 0 0 2 2 2 0 Velvet factor Kelch_6 PF13964.6 GAM22473.1 - 2.5e-07 30.7 3.6 0.00013 22.2 0.0 3.5 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 GAM22473.1 - 8.1e-06 25.7 2.0 0.0015 18.5 0.1 3.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM22473.1 - 1.2e-05 24.8 0.8 0.056 13.0 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 GAM22473.1 - 0.0014 18.9 0.1 0.11 12.9 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM22473.1 - 0.007 16.3 0.9 12 6.1 0.0 3.5 3 1 0 3 3 3 2 Kelch motif FHA PF00498.26 GAM22474.1 - 2.3e-11 43.8 0.3 6.1e-11 42.5 0.3 1.8 1 0 0 1 1 1 1 FHA domain Kelch_6 PF13964.6 GAM22475.1 - 1.5e-10 40.9 4.8 1.4e-05 25.2 0.0 4.6 3 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 GAM22475.1 - 4.6e-07 29.3 1.9 3.3e-05 23.4 0.0 3.6 3 1 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 GAM22475.1 - 3.7e-06 26.8 2.9 0.00012 22.0 0.0 3.3 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM22475.1 - 0.0065 16.7 0.0 1.9 8.9 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM22475.1 - 0.0066 16.4 1.1 0.063 13.3 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Herpes_UL24 PF01646.16 GAM22476.1 - 0.039 13.9 0.1 0.047 13.7 0.1 1.2 1 0 0 1 1 1 0 Herpes virus proteins UL24 and UL76 Kelch_4 PF13418.6 GAM22477.1 - 1.7e-05 24.7 1.4 0.24 11.4 0.1 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM22477.1 - 0.00032 20.9 4.2 0.14 12.5 0.1 3.3 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.25 GAM22477.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.9 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 GAM22478.1 - 3.4e-07 30.3 1.0 0.008 16.4 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 GAM22478.1 - 0.00016 21.6 6.1 0.0016 18.4 0.1 3.2 4 0 0 4 4 3 1 Galactose oxidase, central domain FliT PF05400.13 GAM22478.1 - 0.00036 21.3 1.6 0.088 13.6 0.1 2.3 2 0 0 2 2 2 1 Flagellar protein FliT Kelch_1 PF01344.25 GAM22478.1 - 0.0018 17.8 0.8 0.75 9.4 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 GAM22478.1 - 0.0047 16.9 0.9 0.93 9.6 0.1 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 GAM22478.1 - 0.0098 15.8 2.1 5.5 7.1 0.0 3.3 4 0 0 4 4 3 2 Kelch motif Baculo_PEP_C PF04513.12 GAM22478.1 - 0.012 15.7 0.5 0.012 15.7 0.5 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GLE1 PF07817.13 GAM22478.1 - 0.033 13.4 3.4 0.052 12.8 3.4 1.3 1 0 0 1 1 1 0 GLE1-like protein RyR PF02026.16 GAM22478.1 - 0.037 14.2 1.2 0.098 12.9 1.2 1.8 1 0 0 1 1 1 0 RyR domain Lge1 PF11488.8 GAM22478.1 - 0.32 11.2 3.5 1 9.6 1.7 2.7 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 Syntaxin PF00804.25 GAM22478.1 - 0.42 10.3 7.8 0.29 10.8 2.8 2.1 1 1 1 2 2 2 0 Syntaxin DUF1043 PF06295.12 GAM22478.1 - 0.57 10.2 6.0 0.13 12.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF948 PF06103.11 GAM22478.1 - 3.1 8.1 6.9 9 6.6 0.9 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 GAM22478.1 - 3.5 7.7 5.5 35 4.5 0.7 3.0 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain RecG_N PF17190.4 GAM22478.1 - 6.6 7.5 7.3 11 6.8 0.4 3.0 1 1 1 3 3 3 0 RecG N-terminal helical domain CotJB PF12652.7 GAM22478.1 - 6.7 7.0 6.2 21 5.4 0.1 2.9 3 0 0 3 3 3 0 CotJB protein AATF-Che1 PF13339.6 GAM22478.1 - 7 7.3 8.0 26 5.5 1.0 2.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Snapin_Pallidin PF14712.6 GAM22478.1 - 9.2 6.8 10.8 1.3 9.5 2.9 2.4 2 0 0 2 2 2 0 Snapin/Pallidin PQ-loop PF04193.14 GAM22479.1 - 1.7e-39 133.4 19.4 4.9e-21 74.3 7.9 3.1 3 0 0 3 3 3 2 PQ loop repeat DDE_Tnp_4 PF13359.6 GAM22480.1 - 3.6e-16 59.2 0.0 6.3e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM22480.1 - 1.8e-08 34.3 0.3 3.3e-07 30.2 0.3 2.2 1 1 0 1 1 1 1 Transposase DDE domain PA14 PF07691.12 GAM22481.1 - 4.8e-12 45.9 0.1 8.5e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 GAM22481.1 - 5e-05 23.1 8.5 5e-05 23.1 8.5 13.4 16 0 0 16 16 16 8 Dictyostelium (slime mold) repeat Ribo_biogen_C PF04034.13 GAM22482.1 - 5.7e-53 178.0 0.0 8.7e-53 177.4 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 GAM22482.1 - 1.7e-13 50.1 0.0 3.7e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF1082 PF06449.11 GAM22482.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) Nop14 PF04147.12 GAM22482.1 - 0.9 7.7 64.4 1.3 7.2 64.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAM22482.1 - 2.7 7.3 61.9 0.06 12.8 55.2 1.7 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 GAM22482.1 - 4.1 6.6 54.6 0.063 12.6 47.7 1.4 2 0 0 2 2 2 0 BUD22 Cation_efflux PF01545.21 GAM22483.1 - 8.2e-44 149.7 0.0 1.1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 GAM22483.1 - 8.1 5.6 29.4 5.2 6.2 0.6 3.2 2 1 0 2 2 2 0 ZIP Zinc transporter PPR_2 PF13041.6 GAM22484.1 - 6.1e-24 84.0 0.0 5.1e-08 33.0 0.0 4.4 3 1 1 4 4 4 4 PPR repeat family PPR PF01535.20 GAM22484.1 - 6e-20 70.0 1.7 8.6e-06 25.7 0.0 6.1 6 0 0 6 6 6 4 PPR repeat PPR_3 PF13812.6 GAM22484.1 - 2.2e-16 59.7 0.6 4.6e-08 33.0 0.0 4.9 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAM22484.1 - 7.9e-16 57.5 0.0 4.9e-06 26.1 0.0 6.0 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 GAM22484.1 - 2.9e-08 33.3 0.2 0.016 14.6 0.0 3.1 1 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP HrpB1_HrpK PF09613.10 GAM22484.1 - 0.00063 19.4 0.1 0.0032 17.1 0.0 2.1 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) Ran_BP1 PF00638.18 GAM22485.1 - 4.6e-15 55.9 0.1 1.2e-14 54.7 0.1 1.6 1 0 0 1 1 1 1 RanBP1 domain Dicty_CTDC PF00526.18 GAM22486.1 - 3.4e-84 276.2 183.8 1.5e-12 47.2 8.4 12.6 11 2 0 12 12 12 11 Dictyostelium (slime mold) repeat DUF4674 PF15719.5 GAM22487.1 - 0.033 14.2 1.4 0.034 14.2 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) ATG101 PF07855.12 GAM22488.1 - 7.4e-35 120.2 2.3 9e-35 119.9 2.3 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 CppA_C PF14507.6 GAM22488.1 - 0.06 14.1 0.5 0.093 13.5 0.5 1.3 1 0 0 1 1 1 0 CppA C-terminal Coiled PF05710.12 GAM22489.1 - 1.4e-06 29.0 22.2 2e-06 28.5 22.2 1.3 1 1 0 1 1 1 1 Coiled coil UCH PF00443.29 GAM22490.1 - 5.1e-07 29.4 1.1 5.1e-07 29.4 1.1 4.4 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase AAA_7 PF12775.7 GAM22490.1 - 3.5e-06 26.6 0.5 0.65 9.5 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_22 PF13401.6 GAM22490.1 - 8.8e-06 26.0 0.0 0.43 10.9 0.0 5.8 5 0 0 5 5 5 1 AAA domain AAA PF00004.29 GAM22490.1 - 0.00011 22.7 2.2 0.065 13.7 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM22490.1 - 0.012 15.9 0.0 5.5 7.4 0.0 3.9 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 GAM22490.1 - 0.046 12.8 0.0 0.31 10.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 GAM22490.1 - 0.1 12.6 0.3 88 3.1 0.0 4.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) DUF1206 PF06724.11 GAM22491.1 - 3.9e-13 49.3 21.0 9.2e-06 25.7 0.9 3.2 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) Ndc1_Nup PF09531.10 GAM22491.1 - 0.33 9.6 5.0 0.046 12.4 0.3 1.7 1 1 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF4293 PF14126.6 GAM22491.1 - 1.8 8.8 7.0 0.28 11.4 2.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) XPA_C PF05181.12 GAM22492.1 - 0.0001 22.2 0.1 0.00027 20.8 0.1 1.8 1 0 0 1 1 1 1 XPA protein C-terminus DUF4158 PF13700.6 GAM22492.1 - 0.092 12.6 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) RUN PF02759.19 GAM22493.1 - 0.048 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 RUN domain Secretin_N_2 PF07655.13 GAM22493.1 - 0.5 10.9 9.2 1 9.9 9.2 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain EVI2A PF05399.11 GAM22493.1 - 8.6 5.9 7.5 13 5.3 7.5 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) AAA PF00004.29 GAM22494.1 - 7.1e-09 36.2 2.4 3.8e-05 24.1 0.0 4.3 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAM22494.1 - 2.2e-07 30.6 5.7 0.6 9.6 0.0 5.5 5 0 0 5 5 5 3 P-loop containing dynein motor region AAA_22 PF13401.6 GAM22494.1 - 2.7e-06 27.7 0.1 0.39 11.0 0.0 6.0 7 1 0 7 7 5 1 AAA domain UCH PF00443.29 GAM22494.1 - 1.9e-05 24.3 0.2 1.9e-05 24.3 0.2 2.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase AAA_16 PF13191.6 GAM22494.1 - 0.00063 20.2 0.0 2.9 8.2 0.0 4.0 3 1 0 3 3 3 2 AAA ATPase domain T2SSE PF00437.20 GAM22494.1 - 0.0023 17.0 0.0 0.36 9.8 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_6 PF12774.7 GAM22494.1 - 0.004 16.2 0.0 1.2 8.0 0.0 3.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region IstB_IS21 PF01695.17 GAM22494.1 - 0.012 15.3 0.0 4.2 7.1 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 GAM22494.1 - 0.014 15.3 0.1 3.3 7.6 0.0 3.9 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_19 PF13245.6 GAM22494.1 - 0.016 15.5 0.0 18 5.7 0.0 4.5 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.6 GAM22494.1 - 0.048 13.4 0.0 6.2 6.5 0.0 3.2 3 1 0 3 3 3 0 AAA domain TRAPP PF04051.16 GAM22494.1 - 0.063 13.0 0.0 2.4 7.9 0.0 3.2 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component DUF2177 PF09945.9 GAM22494.1 - 0.072 13.2 1.2 0.16 12.1 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) Ank_2 PF12796.7 GAM22495.1 - 2.9e-30 104.7 29.1 2.2e-11 44.2 0.6 3.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM22495.1 - 1.1e-25 89.6 7.7 1.7e-06 28.5 0.1 5.9 5 1 1 6 6 6 5 Ankyrin repeats (many copies) RGS PF00615.19 GAM22495.1 - 5e-23 81.6 0.2 9.4e-18 64.6 0.0 2.9 3 0 0 3 3 3 2 Regulator of G protein signaling domain Ank_5 PF13857.6 GAM22495.1 - 2.9e-19 68.9 5.8 5e-05 23.5 0.3 4.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM22495.1 - 7e-19 66.0 1.9 0.0052 17.2 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 GAM22495.1 - 2.4e-16 59.3 5.0 0.039 14.4 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat SOG2 PF10428.9 GAM22495.1 - 4.2 6.5 27.4 6.1 5.9 27.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FNIP PF05725.12 GAM22496.1 - 7.6e-25 86.8 0.6 4.7e-10 39.5 0.0 5.7 6 0 0 6 6 6 3 FNIP Repeat SdrD_B PF17210.3 GAM22498.1 - 3.8e-24 85.1 56.9 5.8e-05 23.3 0.2 11.3 5 4 6 11 11 11 8 SdrD B-like domain CooC_C PF15976.5 GAM22498.1 - 5.1e-06 26.4 0.0 13 5.9 0.0 6.5 7 0 0 7 7 7 1 CS1-pili formation C-terminal DUF3823 PF12866.7 GAM22498.1 - 0.00026 21.2 8.9 7.8 6.9 0.1 6.9 7 0 0 7 7 7 1 Protein of unknown function (DUF3823) N-terminal domain Phage_FRD3 PF05798.11 GAM22498.1 - 0.00067 19.9 0.0 35 4.8 0.0 5.2 6 0 0 6 6 6 0 Bacteriophage FRD3 protein DUF2141 PF09912.9 GAM22498.1 - 0.0013 18.6 6.4 2.4 8.1 0.2 7.2 8 1 0 8 8 8 1 Uncharacterized protein conserved in bacteria (DUF2141) Kunitz_BPTI PF00014.23 GAM22498.1 - 0.32 11.3 5.2 7.9 6.8 0.2 4.8 7 0 0 7 7 7 0 Kunitz/Bovine pancreatic trypsin inhibitor domain MIF4G PF02854.19 GAM22501.1 - 0.00041 20.0 1.1 0.0013 18.4 0.7 1.9 1 1 0 1 1 1 1 MIF4G domain TFIIA PF03153.13 GAM22503.1 - 0.0011 19.0 23.9 0.0014 18.8 23.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 GAM22503.1 - 0.0038 16.2 15.6 0.0046 16.0 15.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) ALMT PF11744.8 GAM22503.1 - 0.98 8.2 7.0 1.6 7.5 7.0 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter PepSY_TM PF03929.16 GAM22503.1 - 1.2 8.8 3.2 1.6 8.3 3.2 1.2 1 0 0 1 1 1 0 PepSY-associated TM region TERB2 PF15101.6 GAM22503.1 - 2 8.5 13.7 3.7 7.5 13.7 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4407 PF14362.6 GAM22503.1 - 2 7.7 13.2 4 6.7 13.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ndc1_Nup PF09531.10 GAM22503.1 - 2.7 6.6 9.0 2.8 6.5 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 GAM22503.1 - 4.5 5.9 8.2 5 5.8 8.2 1.2 1 0 0 1 1 1 0 Presenilin Ank_4 PF13637.6 GAM22506.1 - 5.9e-11 42.7 1.0 0.00049 20.6 0.1 3.4 2 2 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM22506.1 - 7.5e-10 38.9 2.4 3e-05 24.2 0.1 4.1 1 1 4 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM22506.1 - 1.7e-08 34.9 1.3 5.8e-07 30.0 0.3 2.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM22506.1 - 0.0059 17.0 0.3 1.3e+02 3.7 0.0 4.6 6 0 0 6 6 6 0 Ankyrin repeat Defensin_propep PF00879.18 GAM22507.1 - 0.1 12.9 0.6 0.13 12.5 0.6 1.2 1 0 0 1 1 1 0 Defensin propeptide WAP PF00095.21 GAM22507.1 - 2 8.8 35.1 0.24 11.8 13.4 2.3 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' ADH_N PF08240.12 GAM22508.1 - 1.5e-28 98.8 4.4 2.5e-28 98.1 4.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM22508.1 - 1.2e-17 64.1 0.1 4.3e-17 62.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 GAM22508.1 - 0.0068 16.2 0.2 0.013 15.3 0.2 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 GAM22508.1 - 0.0078 15.6 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.19 GAM22508.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AlaDh_PNT_C PF01262.21 GAM22508.1 - 0.034 13.4 0.2 0.058 12.7 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Alpha_L_fucos PF01120.17 GAM22509.1 - 8.4e-51 173.5 0.6 1e-50 173.2 0.6 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 GAM22509.1 - 2.5e-16 60.0 0.1 4.4e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain FAD-oxidase_C PF02913.19 GAM22510.1 - 2.3e-59 201.1 0.0 2.9e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAM22510.1 - 3.1e-38 130.6 0.3 5.2e-38 129.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain CH PF00307.31 GAM22511.1 - 8.1e-78 257.7 1.6 2.2e-21 76.1 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM22511.1 - 3.8e-10 39.5 0.7 0.0009 19.0 0.1 3.6 4 0 0 4 4 4 2 CAMSAP CH domain CH_2 PF06294.11 GAM22511.1 - 0.024 14.7 0.0 0.32 11.1 0.0 2.8 3 0 0 3 3 3 0 CH-like domain in sperm protein FAM176 PF14851.6 GAM22513.1 - 1.6 8.4 7.3 0.3 10.8 0.8 2.2 2 1 0 2 2 2 0 FAM176 family Ank_2 PF12796.7 GAM22514.1 - 0.0011 19.5 8.8 1 10.0 0.0 6.0 5 2 1 6 6 6 3 Ankyrin repeats (3 copies) DUF1937 PF09152.10 GAM22514.1 - 0.08 13.8 0.1 0.21 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) Ank_2 PF12796.7 GAM22515.1 - 4.9e-10 39.9 2.4 0.0024 18.4 0.1 5.3 5 0 0 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM22515.1 - 2.9e-07 30.9 2.6 0.094 13.3 0.0 6.9 8 0 0 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM22515.1 - 2.8e-05 24.2 3.7 12 6.8 0.0 7.5 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 GAM22515.1 - 0.00015 22.0 7.6 30 5.1 0.0 7.8 8 0 0 8 8 8 1 Ankyrin repeats (many copies) Luciferase_N PF05295.11 GAM22516.1 - 0.015 15.3 0.2 0.037 14.1 0.2 1.6 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain Ank_2 PF12796.7 GAM22516.1 - 0.038 14.6 0.0 0.21 12.2 0.0 2.0 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Pox_A_type_inc PF04508.12 GAM22516.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat CBS PF00571.28 GAM22518.1 - 0.017 15.5 0.2 0.03 14.8 0.2 1.5 1 1 0 1 1 1 0 CBS domain Homoserine_dh PF00742.19 GAM22519.1 - 6.1e-48 163.0 0.1 1.6e-47 161.6 0.1 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase AA_kinase PF00696.28 GAM22519.1 - 1.3e-38 132.9 0.0 2.4e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family NAD_binding_3 PF03447.16 GAM22519.1 - 1.7e-16 60.9 0.0 4.3e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.6 GAM22519.1 - 3.2e-08 33.2 6.8 1.2e-06 28.2 0.3 3.0 3 0 0 3 3 3 2 ACT domain ACT PF01842.25 GAM22519.1 - 5.9e-08 32.4 1.6 2e-06 27.4 0.1 2.8 2 0 0 2 2 2 1 ACT domain CorA PF01544.18 GAM22520.1 - 5.8e-54 183.4 2.1 7.5e-54 183.0 2.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein NCD1 PF04904.13 GAM22520.1 - 0.11 12.5 0.2 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) DnaJ PF00226.31 GAM22521.1 - 2.9e-17 62.5 0.0 5.3e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.27 GAM22521.1 - 5.9e-12 45.4 0.8 0.0039 17.1 0.0 3.4 2 1 0 3 3 3 3 Mitochondrial carrier protein Ank_4 PF13637.6 GAM22522.1 - 0.0091 16.6 15.6 49 4.7 0.0 9.0 10 1 2 12 12 12 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM22522.1 - 0.014 15.7 1.2 33 5.0 0.0 5.7 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank PF00023.30 GAM22522.1 - 0.031 14.7 0.2 1.4e+02 3.2 0.0 5.4 4 0 0 4 4 4 0 Ankyrin repeat SDA1 PF05285.12 GAM22522.1 - 0.096 12.1 8.2 0.21 11.0 8.2 1.5 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 GAM22522.1 - 0.097 12.0 4.4 0.2 10.9 4.4 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GAM22522.1 - 1.3 7.2 13.4 2.3 6.3 13.4 1.3 1 0 0 1 1 1 0 Nop14-like family Ank_3 PF13606.6 GAM22522.1 - 1.4 9.7 17.8 1e+02 4.0 0.1 9.6 12 0 0 12 12 12 0 Ankyrin repeat RRN3 PF05327.11 GAM22522.1 - 1.6 7.2 8.9 3.1 6.2 8.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 GAM22522.1 - 1.6 6.7 22.8 4.2 5.3 22.8 1.6 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 GAM22522.1 - 5.4 6.7 9.3 14 5.4 9.3 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4645 PF15488.6 GAM22523.1 - 0.028 13.9 0.1 0.03 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) DSPc PF00782.20 GAM22524.1 - 8.3e-29 100.1 0.0 1.5e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM22524.1 - 0.0013 18.3 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAM22524.1 - 0.034 14.1 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 GAM22524.1 - 0.18 11.9 1.9 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 Inositol hexakisphosphate Pyr_redox_2 PF07992.14 GAM22525.1 - 4.2e-41 141.1 0.3 3.7e-37 128.1 0.1 2.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM22525.1 - 1.8e-18 66.9 1.4 4.3e-10 40.0 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM22525.1 - 1.5e-08 34.3 0.0 0.0002 20.7 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM22525.1 - 1.5e-06 28.1 0.0 0.0061 16.2 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAM22525.1 - 8e-05 22.7 0.1 1.5 8.8 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAM22525.1 - 0.00022 20.5 0.0 0.22 10.6 0.0 2.4 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 GAM22525.1 - 0.0018 17.2 0.2 0.028 13.3 0.0 2.5 2 1 1 3 3 3 1 Tryptophan halogenase TrkA_N PF02254.18 GAM22525.1 - 0.0048 17.1 0.3 0.24 11.7 0.0 2.9 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_8 PF13450.6 GAM22525.1 - 0.0059 16.8 0.0 0.032 14.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM22525.1 - 0.0062 15.8 0.0 0.31 10.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAM22525.1 - 0.0071 15.4 0.1 1.5 7.8 0.0 2.9 4 0 0 4 4 4 1 Lycopene cyclase protein DUF1188 PF06690.11 GAM22525.1 - 0.0082 15.7 0.0 0.018 14.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) HI0933_like PF03486.14 GAM22525.1 - 0.013 14.2 0.0 0.076 11.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 GAM22525.1 - 0.016 14.5 0.3 0.051 12.8 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 GAM22525.1 - 0.04 14.4 0.1 1.7 9.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.21 GAM22525.1 - 0.08 12.3 0.1 3.1 7.1 0.0 2.6 3 0 0 3 3 3 0 ThiF family Adap_comp_sub PF00928.21 GAM22527.1 - 6e-21 75.0 0.1 9e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAM22527.1 - 0.0016 18.4 0.2 0.0039 17.1 0.2 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GRP PF07172.11 GAM22527.1 - 0.16 12.6 17.6 0.29 11.8 17.6 1.4 1 0 0 1 1 1 0 Glycine rich protein family DUF719 PF05334.13 GAM22527.1 - 6.1 7.0 7.0 2.7 8.2 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF719) PH PF00169.29 GAM22528.1 - 7.1e-14 52.2 0.5 2.4e-13 50.5 0.5 2.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM22528.1 - 0.00062 20.0 0.1 0.0014 18.9 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Lung_7-TM_R PF06814.13 GAM22529.1 - 1.4e-11 44.2 18.4 4e-11 42.7 18.4 1.7 1 1 0 1 1 1 1 Lung seven transmembrane receptor Bac_export_2 PF01312.19 GAM22529.1 - 0.74 9.0 7.5 0.67 9.1 6.7 1.5 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family Pro-kuma_activ PF09286.11 GAM22530.1 - 5.3e-28 98.1 0.1 9.7e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM22530.1 - 0.026 13.8 0.9 0.046 13.0 0.9 1.3 1 0 0 1 1 1 0 Subtilase family Lipase_3 PF01764.25 GAM22531.1 - 8.3e-29 100.3 0.0 1.1e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GAM22531.1 - 4.7e-05 23.0 0.2 0.00015 21.4 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 GAM22531.1 - 0.029 15.0 0.0 0.048 14.3 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 GAM22531.1 - 0.047 13.4 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ion_trans_2 PF07885.16 GAM22531.1 - 0.051 13.5 1.3 0.44 10.5 0.1 2.4 2 0 0 2 2 2 0 Ion channel Abhydrolase_3 PF07859.13 GAM22531.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acyltransferase PF01553.21 GAM22532.1 - 3.9e-13 49.2 0.0 6.2e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase WD40 PF00400.32 GAM22533.1 - 7.4e-27 93.1 21.8 5.6e-05 23.8 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM22533.1 - 0.00014 22.1 0.3 1.7 9.0 0.0 3.2 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAM22533.1 - 0.078 11.7 0.6 0.47 9.1 0.0 2.1 2 1 0 2 2 2 0 Nup133 N terminal like DUF1921 PF09081.10 GAM22533.1 - 0.13 12.5 0.1 7.7 6.8 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1921) PQ-loop PF04193.14 GAM22534.1 - 6.2e-20 70.7 14.0 1.8e-12 46.8 4.2 4.1 4 1 1 5 5 5 2 PQ loop repeat DUF3687 PF12459.8 GAM22534.1 - 0.044 13.3 0.3 0.044 13.3 0.3 3.5 4 0 0 4 4 4 0 D-Ala-teichoic acid biosynthesis protein DUF2116 PF09889.9 GAM22534.1 - 0.44 10.6 2.1 0.6 10.1 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) MtN3_slv PF03083.16 GAM22534.1 - 0.72 9.9 24.1 0.29 11.2 8.4 3.8 4 0 0 4 4 4 0 Sugar efflux transporter for intercellular exchange PAP2_3 PF14378.6 GAM22535.1 - 1.3e-13 51.1 3.3 1.3e-13 51.1 3.3 2.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 GAM22535.1 - 5.1e-05 23.1 9.7 5.1e-05 23.1 9.7 2.7 2 1 1 3 3 3 2 PAP2 superfamily UPF0242 PF06785.11 GAM22535.1 - 0.18 11.9 2.3 0.32 11.1 2.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spore_III_AB PF09548.10 GAM22536.1 - 0.022 14.9 0.3 0.022 14.9 0.3 2.7 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Rpp20 PF12328.8 GAM22536.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.5 2 1 1 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P RabGAP-TBC PF00566.18 GAM22537.1 - 4.6e-41 140.8 4.8 4.6e-41 140.8 4.8 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Mucin PF01456.17 GAM22537.1 - 0.011 15.7 29.2 1.5 8.8 0.1 2.6 2 1 0 2 2 2 0 Mucin-like glycoprotein Macoilin PF09726.9 GAM22537.1 - 3.2 6.2 29.2 0.13 10.8 9.9 2.2 2 0 0 2 2 2 0 Macoilin family TFIIA PF03153.13 GAM22537.1 - 6 6.8 25.5 0.78 9.7 13.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ras PF00071.22 GAM22538.1 - 3.3e-58 195.9 0.6 3.9e-58 195.6 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM22538.1 - 2.6e-33 114.8 0.3 6.8e-33 113.4 0.0 1.7 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM22538.1 - 1.4e-14 53.9 0.1 1.8e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM22538.1 - 2.7e-09 36.9 0.2 4.1e-09 36.2 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAM22538.1 - 3.9e-07 29.7 0.2 5e-07 29.3 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM22538.1 - 5.1e-05 23.3 0.0 8.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM22538.1 - 0.016 15.1 0.2 6.2 6.7 0.1 2.5 1 1 2 3 3 3 0 RsgA GTPase ATPase_2 PF01637.18 GAM22538.1 - 0.024 14.6 0.0 0.063 13.2 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea G-alpha PF00503.20 GAM22538.1 - 0.034 13.3 0.1 0.3 10.2 0.1 2.0 1 1 0 1 1 1 0 G-protein alpha subunit ABC_transp_aux PF09822.9 GAM22538.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 ABC-type uncharacterized transport system AAA_25 PF13481.6 GAM22538.1 - 0.083 12.5 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAM22538.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain ETF PF01012.21 GAM22539.1 - 2.1e-45 154.8 1.7 2.7e-45 154.5 1.7 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TPP_enzyme_M PF00205.22 GAM22539.1 - 0.03 14.1 0.2 0.072 12.8 0.1 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Dynamin_M PF01031.20 GAM22540.1 - 1.2e-104 349.6 0.8 2.1e-104 348.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 GAM22540.1 - 9.4e-59 198.2 5.7 3e-58 196.6 0.0 2.9 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 GAM22540.1 - 2.1e-33 114.4 2.6 7.2e-33 112.6 2.6 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAM22540.1 - 3.8e-05 23.7 0.1 0.00036 20.6 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM22540.1 - 0.15 11.6 1.6 21 4.6 0.1 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B CH PF00307.31 GAM22541.1 - 1.2e-13 51.2 0.0 3.3e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain RhoGEF PF00621.20 GAM22541.1 - 8.3e-09 35.9 1.7 1.3e-08 35.3 0.0 2.3 3 0 0 3 3 3 1 RhoGEF domain IQ_SEC7_PH PF16453.5 GAM22541.1 - 8e-07 29.1 0.1 2.3e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 GAM22541.1 - 6.5e-06 26.0 0.5 6.5e-06 26.0 0.5 2.1 1 1 1 2 2 2 1 Pleckstrin homology domain PH PF00169.29 GAM22541.1 - 1.1e-05 25.9 0.1 4.1e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 PH domain ACP_PD PF04336.12 GAM22541.1 - 0.052 14.0 0.3 0.16 12.4 0.3 1.8 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase CAMSAP_CH PF11971.8 GAM22541.1 - 0.096 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain Adenine_glyco PF03352.13 GAM22541.1 - 0.98 9.2 4.3 0.38 10.5 1.6 1.7 2 0 0 2 2 2 0 Methyladenine glycosylase IBR PF01485.21 GAM22542.1 - 7.2e-11 42.2 57.5 5.3e-06 26.6 8.1 5.0 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 GAM22542.1 - 1.2e-07 32.0 0.1 3.6e-07 30.5 0.1 1.8 1 0 0 1 1 1 1 RWD domain zf-RING_5 PF14634.6 GAM22542.1 - 0.00018 21.4 8.9 0.00018 21.4 8.9 5.2 4 1 1 5 5 5 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM22542.1 - 0.00034 20.6 8.4 0.00034 20.6 8.4 4.5 4 0 0 4 4 4 2 RING-type zinc-finger zf-RING_2 PF13639.6 GAM22542.1 - 0.0012 19.2 7.8 0.0012 19.2 7.8 4.8 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 GAM22542.1 - 0.0068 16.2 7.0 0.0068 16.2 7.0 5.4 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 GAM22542.1 - 0.019 15.1 5.1 0.019 15.1 5.1 4.4 4 1 0 4 4 4 0 Zinc-binding RING-finger Hexapep PF00132.24 GAM22543.1 - 2.4e-10 39.7 6.4 6.5e-05 22.5 0.0 4.1 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAM22543.1 - 9.3e-07 28.5 0.2 0.0023 17.6 0.0 2.8 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 GAM22543.1 - 0.14 11.1 0.2 0.53 9.2 0.1 1.8 2 0 0 2 2 2 0 L-fucokinase RNA_pol_Rpb8 PF03870.15 GAM22544.1 - 1.5e-47 161.3 0.2 1.7e-47 161.1 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 GAM22544.1 - 0.00026 21.0 0.1 0.0045 17.0 0.1 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase, subunit G Lipase_3 PF01764.25 GAM22545.1 - 1.1e-18 67.5 0.0 5.3e-18 65.2 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) Pox_RNA_Pol_19 PF05320.12 GAM22545.1 - 0.38 10.7 4.2 1.4 8.9 4.2 2.0 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit BSP_II PF05432.11 GAM22545.1 - 1.5 8.4 12.3 2.4 7.8 1.0 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TIG PF01833.24 GAM22546.1 - 4.3e-49 164.5 193.5 1.6e-07 31.3 5.1 18.5 15 3 3 18 18 18 16 IPT/TIG domain PLAT PF01477.23 GAM22546.1 - 4.3 7.9 7.2 1.1 9.8 0.1 3.8 4 0 0 4 4 4 0 PLAT/LH2 domain Menin PF05053.13 GAM22548.1 - 0.023 13.1 7.1 0.035 12.5 7.1 1.2 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 GAM22548.1 - 0.13 11.0 5.7 0.21 10.3 5.7 1.2 1 0 0 1 1 1 0 Presenilin PI3K_1B_p101 PF10486.9 GAM22548.1 - 0.6 7.8 7.5 1 7.1 7.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 GAM22548.1 - 1 7.8 13.4 1.6 7.2 13.4 1.1 1 0 0 1 1 1 0 Macoilin family SRAP PF02586.14 GAM22549.1 - 1.8e-22 80.0 0.1 2.4e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) SOG2 PF10428.9 GAM22550.1 - 0.24 10.5 18.4 0.26 10.5 18.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein RTX_C PF08339.10 GAM22550.1 - 0.73 9.9 4.4 1.1 9.3 4.4 1.3 1 0 0 1 1 1 0 RTX C-terminal domain QWRF PF04484.12 GAM22550.1 - 6.2 6.5 15.3 7.1 6.3 15.3 1.1 1 0 0 1 1 1 0 QWRF family XPG_N PF00752.17 GAM22551.1 - 1.7e-08 34.8 0.1 1.9e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain DUF4611 PF15387.6 GAM22551.1 - 0.33 11.2 3.4 0.64 10.3 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Uso1_p115_C PF04871.13 GAM22551.1 - 4.8 7.6 7.5 20 5.6 7.9 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FMN_red PF03358.15 GAM22552.1 - 3.8e-28 98.2 0.0 4.7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAM22552.1 - 1.3e-05 25.1 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold AgrD PF05931.11 GAM22552.1 - 0.013 15.5 0.0 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 Staphylococcal AgrD protein Prefoldin_2 PF01920.20 GAM22553.1 - 4.7e-19 68.3 14.1 4.7e-19 68.3 14.1 2.1 1 1 1 2 2 2 1 Prefoldin subunit HNHc_6 PF16784.5 GAM22553.1 - 0.028 14.0 0.3 0.042 13.4 0.3 1.3 1 0 0 1 1 1 0 Putative HNHc nuclease Tup_N PF08581.10 GAM22553.1 - 0.056 13.8 12.0 3.2 8.1 1.6 3.4 1 1 2 3 3 3 0 Tup N-terminal DUF2203 PF09969.9 GAM22553.1 - 0.29 11.9 7.0 0.21 12.3 5.1 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF501 PF04417.12 GAM22553.1 - 0.48 10.2 5.1 2.2 8.1 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) COG2 PF06148.11 GAM22553.1 - 0.48 10.5 12.2 1.5 8.9 2.5 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.7 GAM22553.1 - 0.5 10.5 20.3 0.42 10.8 6.4 2.2 2 0 0 2 2 2 0 Tropomyosin like MCU PF04678.13 GAM22553.1 - 2.6 8.1 7.4 1.9 8.6 2.3 2.1 1 1 1 2 2 2 0 Mitochondrial calcium uniporter DUF948 PF06103.11 GAM22553.1 - 6.5 7.1 11.3 1.2 9.5 1.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Sugar_tr PF00083.24 GAM22554.1 - 3.1e-91 306.5 38.2 3.3e-90 303.1 38.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM22554.1 - 1.1e-30 106.8 62.6 6.6e-25 87.8 31.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TIMELESS PF04821.14 GAM22555.1 - 2.8e-45 154.7 5.1 2.8e-45 154.7 5.1 2.2 2 0 0 2 2 2 1 Timeless protein RRM_1 PF00076.22 GAM22556.1 - 1.2e-09 37.9 0.1 1.4e-06 28.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1062 PF06353.12 GAM22556.1 - 0.12 13.2 0.0 0.21 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) Ank_2 PF12796.7 GAM22557.1 - 5.2e-06 27.0 4.7 0.019 15.6 0.0 5.3 6 0 0 6 6 6 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM22557.1 - 0.00063 20.0 0.6 1.5e+02 3.5 0.0 6.4 6 0 0 6 6 6 0 Ankyrin repeat KbaA PF14089.6 GAM22557.1 - 0.15 11.9 0.1 2 8.2 0.1 2.3 1 1 0 1 1 1 0 KinB-signalling pathway activation in sporulation DUF3447 PF11929.8 GAM22557.1 - 9.2 6.3 7.4 1.2 9.1 0.1 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF3447) DUF1411 PF07199.11 GAM22558.1 - 0.15 11.7 0.2 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) Excalibur PF05901.11 GAM22558.1 - 2.1 9.0 6.4 25 5.6 1.4 3.2 2 1 0 2 2 2 0 Excalibur calcium-binding domain Kelch_6 PF13964.6 GAM22560.1 - 6.7e-13 48.4 7.6 0.0001 22.4 0.0 5.0 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM22560.1 - 3.8e-10 39.6 0.3 8e-05 22.6 0.0 3.8 3 0 0 3 3 3 3 Galactose oxidase, central domain zf-B_box PF00643.24 GAM22560.1 - 1.4e-06 28.3 7.8 1.4e-06 28.3 7.8 2.0 2 0 0 2 2 2 1 B-box zinc finger Kelch_1 PF01344.25 GAM22560.1 - 0.00052 19.5 3.3 0.012 15.2 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAM22560.1 - 0.036 14.1 1.7 63 3.8 0.1 3.9 3 0 0 3 3 3 0 Kelch motif SPATA9 PF15824.5 GAM22560.1 - 0.039 13.2 0.0 0.1 11.8 0.0 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 LIP PF03583.14 GAM22560.1 - 0.043 13.1 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase FliT PF05400.13 GAM22560.1 - 0.2 12.5 0.4 0.36 11.7 0.4 1.4 1 0 0 1 1 1 0 Flagellar protein FliT AIF_C PF14721.6 GAM22560.1 - 0.35 11.2 4.9 0.75 10.2 4.9 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Presenilin PF01080.17 GAM22560.1 - 1.1 8.0 3.8 1.6 7.4 3.8 1.2 1 0 0 1 1 1 0 Presenilin Q_salvage PF10343.9 GAM22561.1 - 2.5e-85 286.5 0.0 3.6e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 GAM22561.1 - 0.002 16.9 0.0 0.59 8.8 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1688) Lipase_3 PF01764.25 GAM22562.1 - 5.6e-24 84.6 0.0 7e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 GAM22562.1 - 0.0092 15.7 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein TFIIB PF00382.19 GAM22563.1 - 1.1e-25 89.5 0.1 1.5e-15 57.0 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 GAM22563.1 - 1.6e-09 37.1 1.1 2.9e-09 36.3 1.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 GAM22563.1 - 0.0013 18.8 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 Cyclin, C-terminal domain Yopt PF09467.10 GAM22563.1 - 0.017 15.1 1.8 0.074 13.1 0.0 2.7 3 0 0 3 3 3 0 Hypothetical protein Yopt HTH_Tnp_ISL3 PF13542.6 GAM22563.1 - 0.017 14.5 0.1 0.056 12.9 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Skp1_POZ PF03931.15 GAM22564.1 - 7.5e-07 29.2 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 GAM22564.1 - 0.0013 19.0 0.8 0.0034 17.6 0.2 1.9 1 1 1 2 2 2 1 BTB/POZ domain Aminotran_5 PF00266.19 GAM22565.1 - 1.3e-11 44.1 0.0 2.6e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Abhydrolase_6 PF12697.7 GAM22565.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Aminotran_1_2 PF00155.21 GAM22566.1 - 4.9e-94 315.5 0.0 5.5e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Myb_DNA-bind_6 PF13921.6 GAM22566.1 - 0.13 12.6 0.0 2.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Glyco_hydro_38N PF01074.22 GAM22567.1 - 4.5e-39 134.5 0.3 4.5e-39 134.5 0.3 2.5 2 1 1 3 3 3 1 Glycosyl hydrolases family 38 N-terminal domain SARAF PF06682.12 GAM22567.1 - 0.054 13.1 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis His_biosynth PF00977.21 GAM22567.1 - 0.06 12.8 2.4 0.18 11.2 2.4 1.8 1 0 0 1 1 1 0 Histidine biosynthesis protein Mago_nashi PF02792.14 GAM22567.1 - 1.9 8.6 4.9 1.1 9.3 0.3 2.8 2 1 0 2 2 2 0 Mago nashi protein Elf1 PF05129.13 GAM22568.1 - 2.9e-30 104.1 2.6 3.4e-30 103.9 2.6 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.19 GAM22568.1 - 0.19 11.8 3.2 0.14 12.3 1.6 1.6 1 1 0 1 1 1 0 Ribosomal L37ae protein family FNIP PF05725.12 GAM22569.1 - 1.5e-64 213.9 30.1 5e-16 58.6 2.1 8.6 4 2 4 9 9 9 9 FNIP Repeat LRR_8 PF13855.6 GAM22569.1 - 0.011 15.4 2.7 20 5.0 0.0 5.0 5 2 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 GAM22569.1 - 6.6 7.7 15.1 82 4.4 0.1 6.8 7 2 1 8 8 8 0 Leucine Rich Repeat Ribosomal_S15 PF00312.22 GAM22570.1 - 1.5e-11 44.3 0.1 1.9e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 HicB PF05534.12 GAM22570.1 - 0.027 14.3 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 HicB family G-alpha PF00503.20 GAM22571.1 - 1.3e-56 192.3 15.9 2.5e-56 191.4 15.9 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM22571.1 - 5.3e-07 29.3 0.0 1.3e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family zf-C3HC PF07967.13 GAM22572.1 - 5.5e-32 110.6 2.9 1.4e-29 102.8 0.1 3.4 3 0 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.10 GAM22572.1 - 2e-11 43.9 12.1 7.7e-07 29.2 0.3 4.6 4 1 0 4 4 4 2 Rsm1-like DUF3219 PF11514.8 GAM22572.1 - 0.11 12.6 0.0 0.9 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3219) Put_Phosphatase PF06888.12 GAM22572.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Putative Phosphatase DUF3740 PF12548.8 GAM22572.1 - 0.23 11.9 0.1 0.23 11.9 0.1 2.2 3 0 0 3 3 3 0 Sulfatase protein BIR PF00653.21 GAM22572.1 - 0.42 11.3 2.8 7.8 7.2 0.1 2.8 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Stc1 PF12898.7 GAM22572.1 - 1.2 9.7 4.7 0.75 10.4 0.2 2.8 2 1 0 2 2 2 0 Stc1 domain Ribosomal_S26e PF01283.19 GAM22573.1 - 2.3e-47 159.9 8.2 2.6e-47 159.7 8.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 GAM22573.1 - 0.28 11.8 4.3 1.7 9.3 4.5 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Ribosomal_L19e PF01280.20 GAM22574.1 - 1.3e-29 103.1 7.5 1.6e-19 70.4 0.0 3.0 2 1 1 3 3 3 2 Ribosomal protein L19e Zn_ribbon_SprT PF17283.2 GAM22574.1 - 0.37 10.7 1.9 1.3 9.0 0.9 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Phe_tRNA-synt_N PF02912.18 GAM22575.1 - 0.11 12.4 0.4 0.25 11.3 0.4 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Glyco_hydro_38N PF01074.22 GAM22576.1 - 1.2e-69 234.8 0.7 2.2e-69 234.0 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAM22576.1 - 3.1e-21 76.4 0.1 5.1e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAM22576.1 - 3.4e-15 56.0 2.1 7e-15 55.0 2.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain MIT PF04212.18 GAM22577.1 - 1.8e-10 40.8 2.7 4.3e-10 39.5 2.7 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain ECH_1 PF00378.20 GAM22577.1 - 0.008 15.5 0.1 0.035 13.4 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase BRO1 PF03097.18 GAM22577.1 - 0.027 13.3 0.6 0.088 11.6 0.1 1.8 2 0 0 2 2 2 0 BRO1-like domain TPR_2 PF07719.17 GAM22577.1 - 0.035 14.2 0.6 0.035 14.2 0.6 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM22577.1 - 0.041 13.6 0.3 0.095 12.4 0.3 1.6 1 0 0 1 1 1 0 TPR repeat Mitoc_L55 PF09776.9 GAM22577.1 - 0.096 12.4 0.1 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 PspB PF06667.12 GAM22577.1 - 0.15 12.1 0.2 0.38 10.8 0.2 1.6 1 0 0 1 1 1 0 Phage shock protein B Ank_2 PF12796.7 GAM22579.1 - 0.036 14.7 0.2 1.1 9.9 0.1 2.2 1 1 2 3 3 3 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM22579.1 - 0.18 12.4 0.9 45 5.1 0.1 3.7 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 GAM22580.1 - 0.00057 20.4 0.1 0.0013 19.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM22580.1 - 0.0014 19.1 0.1 0.0045 17.5 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM22580.1 - 0.13 12.9 0.0 1.6 9.6 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat UPF0556 PF10572.9 GAM22580.1 - 0.15 11.5 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0556 Pkinase PF00069.25 GAM22581.1 - 3.6e-53 180.6 0.0 5.4e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22581.1 - 4.6e-35 121.2 0.0 7.8e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM22581.1 - 8.7e-05 21.5 0.0 0.00048 19.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAM22581.1 - 0.0063 15.9 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like SUIM_assoc PF16619.5 GAM22581.1 - 0.01 15.9 0.0 0.028 14.5 0.0 1.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Kdo PF06293.14 GAM22581.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUDE_C PF04880.13 GAM22581.1 - 0.7 10.3 8.6 1.4 9.3 8.6 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Cytadhesin_P30 PF07271.11 GAM22581.1 - 1.8 8.1 7.1 3.1 7.3 7.1 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 Connexin PF00029.19 GAM22582.1 - 0.0093 15.8 0.4 0.012 15.4 0.4 1.1 1 0 0 1 1 1 1 Connexin CCDC106 PF15794.5 GAM22582.1 - 0.027 14.2 0.3 0.037 13.7 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Herpes_BLRF2 PF05812.12 GAM22582.1 - 0.034 14.3 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein T4SS PF07996.11 GAM22582.1 - 0.14 12.5 3.4 0.17 12.3 3.4 1.3 1 1 0 1 1 1 0 Type IV secretion system proteins Apis_Csd PF11671.8 GAM22582.1 - 0.23 11.5 8.9 0.32 11.0 8.9 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein YabA PF06156.13 GAM22582.1 - 2.7 8.7 9.3 38 5.0 9.3 2.1 1 1 0 1 1 1 0 Initiation control protein YabA PI3Ka PF00613.20 GAM22583.1 - 5.8e-59 198.6 1.2 9.6e-59 197.9 1.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 GAM22583.1 - 3.6e-55 187.5 0.0 1.4e-53 182.3 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 GAM22583.1 - 7.8e-24 84.2 0.0 2.4e-23 82.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 GAM22583.1 - 9.3e-14 51.5 1.1 4.8e-09 36.3 0.0 3.5 3 0 0 3 3 3 2 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 GAM22583.1 - 0.0035 16.7 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) HEAT_2 PF13646.6 GAM22583.1 - 0.051 14.0 0.1 0.17 12.3 0.1 1.8 1 0 0 1 1 1 0 HEAT repeats WD40 PF00400.32 GAM22584.1 - 4.5e-55 182.4 28.5 2.3e-07 31.4 0.2 10.3 10 0 0 10 10 10 9 WD domain, G-beta repeat Utp13 PF08625.11 GAM22584.1 - 6.8e-41 139.5 2.7 1.6e-40 138.3 2.7 1.7 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 GAM22584.1 - 1.5e-23 82.8 10.0 6.2e-06 26.4 0.1 7.6 4 3 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM22584.1 - 2.9e-11 42.7 16.5 0.00093 18.0 0.1 7.7 2 2 6 8 8 8 4 Nucleoporin Nup120/160 WD40_like PF17005.5 GAM22584.1 - 4.7e-06 26.1 9.7 0.081 12.2 0.1 4.7 2 1 1 3 3 3 2 WD40-like domain Hira PF07569.11 GAM22584.1 - 2.8e-05 24.0 6.6 0.078 12.7 0.0 5.5 5 1 1 6 6 6 2 TUP1-like enhancer of split Nucleoporin_N PF08801.11 GAM22584.1 - 4.7e-05 22.3 16.2 2.7 6.6 0.5 7.3 3 2 3 7 7 7 4 Nup133 N terminal like BBS2_Mid PF14783.6 GAM22584.1 - 0.00014 21.8 1.8 19 5.4 0.0 5.9 4 1 4 8 8 8 0 Ciliary BBSome complex subunit 2, middle region UTP15_C PF09384.10 GAM22584.1 - 0.037 13.7 1.9 0.079 12.6 1.9 1.5 1 0 0 1 1 1 0 UTP15 C terminal DDR_swiveling PF18427.1 GAM22584.1 - 0.12 12.4 0.1 0.37 10.8 0.1 1.8 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain CENP-B_dimeris PF09026.10 GAM22585.1 - 0.015 15.6 4.6 0.061 13.7 4.6 1.9 1 1 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_A24 PF01478.18 GAM22586.1 - 1.4 9.3 9.6 1.4 9.4 4.2 2.3 2 0 0 2 2 2 0 Type IV leader peptidase family DUF3099 PF11298.8 GAM22586.1 - 3.9 7.7 9.7 6.9 6.9 2.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3099) TBCC PF07986.12 GAM22587.1 - 2.8e-25 88.4 10.7 5.1e-25 87.5 10.7 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 GAM22587.1 - 0.13 11.9 5.8 0.29 10.8 5.8 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal NUDIX PF00293.28 GAM22588.1 - 8.7e-12 45.2 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Seipin PF06775.14 GAM22589.1 - 1.2e-44 152.8 2.4 1.9e-44 152.1 2.4 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DIOX_N PF14226.6 GAM22591.1 - 5.7e-09 36.7 0.0 1.2e-08 35.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal TH1 PF04858.13 GAM22593.1 - 2.5e-83 280.7 6.4 1.8e-53 182.1 0.7 3.0 1 1 1 2 2 2 2 TH1 protein LXG PF04740.12 GAM22593.1 - 0.012 15.4 0.8 0.17 11.6 0.8 2.3 1 1 0 1 1 1 0 LXG domain of WXG superfamily Baculo_19 PF04798.12 GAM22593.1 - 0.022 14.5 1.0 0.33 10.7 0.4 2.4 2 0 0 2 2 2 0 Baculovirus 19 kDa protein conserved region Talin_middle PF09141.10 GAM22593.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Talin, middle domain TH1 PF04858.13 GAM22594.1 - 4.1e-29 101.7 0.0 4.3e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 TH1 protein PRCC PF10253.9 GAM22594.1 - 0.064 14.0 12.1 0.068 14.0 12.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 GAM22594.1 - 0.069 12.3 14.5 0.078 12.2 14.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4135 PF13575.6 GAM22594.1 - 0.1 11.9 0.2 0.12 11.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Ndc1_Nup PF09531.10 GAM22594.1 - 0.96 8.1 6.0 0.93 8.1 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 GAM22594.1 - 1.1 9.1 6.6 1.2 9.1 6.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med13_C PF06333.12 GAM22594.1 - 1.5 8.0 13.2 1.9 7.7 13.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain TFIIA PF03153.13 GAM22594.1 - 2.3 8.1 13.1 2.6 8.0 13.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 GAM22594.1 - 8.1 6.0 16.3 12 5.4 16.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF4405 PF14358.6 GAM22595.1 - 0.00099 19.6 0.1 0.0025 18.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4405) Vps26 PF03643.15 GAM22595.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 zf-RING_2 PF13639.6 GAM22596.1 - 0.032 14.6 3.1 0.032 14.6 3.1 1.8 2 0 0 2 2 2 0 Ring finger domain Form_Nir_trans PF01226.17 GAM22596.1 - 0.047 13.0 4.8 0.069 12.5 4.8 1.2 1 0 0 1 1 1 0 Formate/nitrite transporter Phage_holin_3_6 PF07332.11 GAM22596.1 - 0.049 13.7 4.4 0.086 12.9 4.4 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 GAM22596.1 - 0.059 12.1 0.1 0.081 11.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) U-box PF04564.15 GAM22596.1 - 0.068 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 U-box domain SseC PF04888.12 GAM22596.1 - 0.14 11.7 2.3 0.23 11.0 2.3 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family FNIP PF05725.12 GAM22597.1 - 1.9e-56 188.0 33.3 1.1e-08 35.1 0.0 12.8 4 3 8 13 13 13 11 FNIP Repeat Rtt106_N PF18215.1 GAM22597.1 - 0.034 13.9 0.2 29 4.5 0.0 4.2 4 0 0 4 4 4 0 Histone chaperone Rtt106 N-terminal domain DUF1505 PF07403.11 GAM22598.1 - 0.21 11.8 0.1 0.21 11.8 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1505) tRNA-synt_1e PF01406.19 GAM22599.1 - 1.9e-114 382.1 0.1 3.4e-114 381.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAM22599.1 - 7.1e-07 28.3 1.2 0.00047 19.0 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 GAM22599.1 - 0.0025 16.7 1.5 0.0028 16.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1 PF00133.22 GAM22599.1 - 0.0043 15.4 0.0 0.013 13.8 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) AAA-ATPase_like PF09820.9 GAM22599.1 - 0.0083 15.6 0.3 0.021 14.2 0.3 1.6 1 0 0 1 1 1 1 Predicted AAA-ATPase FNIP PF05725.12 GAM22600.1 - 6e-52 173.6 47.2 1.6e-16 60.2 0.4 8.9 3 2 8 11 11 11 11 FNIP Repeat TPR_12 PF13424.6 GAM22601.1 - 6.5e-10 39.2 3.8 0.00031 21.0 2.3 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAM22601.1 - 6.8e-09 35.0 3.3 8.1e-06 25.2 0.3 3.1 3 0 0 3 3 3 2 SHNi-TPR TPR_2 PF07719.17 GAM22601.1 - 1e-06 28.4 1.6 0.0057 16.7 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM22601.1 - 0.0011 19.0 7.8 0.67 10.3 0.2 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM22601.1 - 0.011 15.5 5.8 1.4 8.9 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Holin_BhlA PF10960.8 GAM22601.1 - 0.012 15.6 0.1 0.037 14.0 0.1 1.9 1 0 0 1 1 1 0 BhlA holin family Mucin PF01456.17 GAM22601.1 - 0.014 15.4 7.1 0.014 15.4 7.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2225 PF09986.9 GAM22601.1 - 0.023 14.4 1.6 0.04 13.6 1.2 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 GAM22601.1 - 0.041 14.1 1.4 1.8 8.9 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAM22601.1 - 0.68 9.7 2.7 2.1 8.1 0.2 2.8 3 0 0 3 3 3 0 TPR repeat T2SSC PF11356.8 GAM22601.1 - 5.1 7.0 7.6 1.3 8.9 3.5 2.1 2 0 0 2 2 2 0 Type II secretion system protein C Dicty_REP PF05086.12 GAM22601.1 - 5.3 4.9 15.7 0.097 10.6 0.3 2.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Alba PF01918.21 GAM22602.1 - 2.1e-11 43.4 0.1 3.4e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Alba NAC PF01849.18 GAM22603.1 - 5e-18 64.8 0.1 1.3e-17 63.5 0.1 1.8 1 0 0 1 1 1 1 NAC domain Fer4_15 PF13459.6 GAM22603.1 - 0.37 11.6 3.4 1 10.2 0.0 2.7 3 1 0 3 3 3 0 4Fe-4S single cluster domain Mucin PF01456.17 GAM22603.1 - 1 9.3 17.2 0.65 10.0 10.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Stm1_N PF09598.10 GAM22603.1 - 1.6 9.6 9.0 5.7 7.9 0.5 2.7 2 1 1 3 3 3 0 Stm1 DUF3306 PF11748.8 GAM22603.1 - 7.7 7.4 10.0 8.3 7.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Aminotran_1_2 PF00155.21 GAM22604.1 - 2.7e-83 280.2 0.0 3e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PsiB PF06290.11 GAM22604.1 - 0.087 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) KORA PF16509.5 GAM22604.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor WD40 PF00400.32 GAM22605.1 - 2.9e-18 65.9 24.3 3.3e-07 30.9 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat WD40_like PF17005.5 GAM22605.1 - 2.1e-08 33.8 0.3 4.7e-05 22.9 0.2 3.5 3 1 0 3 3 3 2 WD40-like domain BBS2_Mid PF14783.6 GAM22605.1 - 1.2e-05 25.3 0.1 4.9 7.2 0.0 4.0 3 1 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 GAM22605.1 - 2.6e-05 24.4 1.5 0.28 11.5 0.0 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM22605.1 - 0.00026 20.1 0.6 0.00066 18.7 0.0 2.0 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIA PF03153.13 GAM22605.1 - 6.8 6.6 16.2 10 6.0 16.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP PF05725.12 GAM22606.1 - 1.4e-94 310.0 12.2 6.4e-17 61.4 0.0 10.5 4 3 2 11 11 11 11 FNIP Repeat GCV_T_C PF08669.11 GAM22606.1 - 0.14 12.1 0.0 14 5.7 0.0 3.5 3 1 0 3 3 3 0 Glycine cleavage T-protein C-terminal barrel domain E1-E2_ATPase PF00122.20 GAM22607.1 - 2.8e-49 167.1 1.0 2.8e-49 167.1 1.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM22607.1 - 3.1e-43 148.5 0.1 5.4e-43 147.7 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAM22607.1 - 6.1e-22 77.8 10.2 1.4e-10 41.5 0.1 4.4 4 0 0 4 4 4 2 Heavy-metal-associated domain HAD PF12710.7 GAM22607.1 - 0.00064 20.2 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAM22607.1 - 0.0053 16.5 10.8 0.033 13.9 0.1 4.6 4 2 0 5 5 5 2 haloacid dehalogenase-like hydrolase TctB PF07331.11 GAM22607.1 - 1.1 9.5 18.7 0.057 13.7 1.6 3.3 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family Oleosin PF01277.17 GAM22608.1 - 0.0013 18.5 0.1 0.003 17.3 0.1 1.6 1 0 0 1 1 1 1 Oleosin LapA_dom PF06305.11 GAM22608.1 - 0.0028 17.4 1.0 0.0058 16.4 1.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain EGF_2 PF07974.13 GAM22608.1 - 0.014 15.8 12.0 0.026 14.9 12.0 1.5 1 0 0 1 1 1 0 EGF-like domain Vpu PF00558.19 GAM22608.1 - 0.059 13.1 2.0 0.1 12.4 2.0 1.4 1 0 0 1 1 1 0 Vpu protein EGF PF00008.27 GAM22608.1 - 2.8 8.3 7.7 5.6 7.4 7.7 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 GAM22609.1 - 0.03 14.7 11.9 0.053 13.9 11.9 1.4 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.24 GAM22609.1 - 0.18 11.9 6.0 0.051 13.6 0.9 2.9 3 0 0 3 3 3 0 IPT/TIG domain EGF PF00008.27 GAM22609.1 - 0.38 11.1 8.7 0.72 10.2 8.7 1.5 1 0 0 1 1 1 0 EGF-like domain Cadherin-like PF12733.7 GAM22609.1 - 0.88 10.1 12.1 3.3 8.3 0.7 4.8 3 2 1 4 4 4 0 Cadherin-like beta sandwich domain SOG2 PF10428.9 GAM22611.1 - 3.9 6.6 26.2 0.34 10.1 12.5 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein EVI2A PF05399.11 GAM22611.1 - 9.7 5.7 22.7 6.2 6.3 3.9 2.1 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) YchF-GTPase_C PF06071.13 GAM22612.1 - 2e-34 117.6 0.2 7e-34 115.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 GAM22612.1 - 4.4e-22 78.3 0.0 1e-21 77.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM22612.1 - 1.1e-06 28.2 0.0 2.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 GAM22612.1 - 0.04 12.9 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Filamin PF00630.19 GAM22613.1 - 5.2e-124 406.2 11.9 6e-23 81.6 0.1 6.2 6 0 0 6 6 6 6 Filamin/ABP280 repeat CH PF00307.31 GAM22613.1 - 1.4e-44 150.7 0.6 4e-23 81.7 0.8 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain Invasin_D3 PF09134.10 GAM22613.1 - 7.3e-27 93.5 7.7 0.0045 17.3 0.0 6.3 6 0 0 6 6 6 6 Invasin, domain 3 YtkA PF13115.6 GAM22613.1 - 1.6e-11 44.7 8.3 0.075 13.6 0.0 6.3 6 0 0 6 6 6 5 YtkA-like Y_Y_Y PF07495.13 GAM22613.1 - 3.3e-09 36.6 2.6 0.36 10.8 0.0 5.8 5 0 0 5 5 5 4 Y_Y_Y domain CAMSAP_CH PF11971.8 GAM22613.1 - 1.5e-07 31.2 0.1 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain DUF5060 PF16586.5 GAM22613.1 - 2.2e-06 27.9 1.0 3.7 8.0 0.0 5.1 5 0 0 5 5 5 2 Domain of unknown function (DUF5060) Big_6 PF17936.1 GAM22613.1 - 2.7e-05 24.3 17.7 0.91 9.8 0.1 7.1 7 1 1 8 8 8 2 Bacterial Ig domain Big_1 PF02369.16 GAM22613.1 - 0.00035 20.5 10.4 1.3 9.0 0.6 5.9 6 0 0 6 6 6 2 Bacterial Ig-like domain (group 1) Neurexophilin PF06312.12 GAM22613.1 - 0.15 11.5 3.4 93 2.4 0.0 4.7 6 0 0 6 6 6 0 Neurexophilin He_PIG PF05345.12 GAM22613.1 - 2.3 8.5 23.0 5.4 7.3 0.3 7.1 8 0 0 8 8 8 0 Putative Ig domain Cadherin_5 PF17892.1 GAM22613.1 - 2.8 8.0 18.7 1.9 8.5 0.3 5.5 6 0 0 6 6 6 0 Cadherin-like domain Glyco_hydro2_C5 PF18565.1 GAM22613.1 - 7.6 6.4 12.3 14 5.6 0.0 5.2 6 0 0 6 6 6 0 Glycoside hydrolase family 2 C-terminal domain 5 Dicty_REP PF05086.12 GAM22615.1 - 0.0049 14.9 7.3 0.0053 14.8 7.3 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein SprA-related PF12118.8 GAM22615.1 - 0.13 11.4 7.0 0.15 11.2 7.0 1.1 1 0 0 1 1 1 0 SprA-related family NAM-associated PF14303.6 GAM22615.1 - 0.14 12.9 6.5 0.2 12.4 6.5 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Mucin PF01456.17 GAM22615.1 - 0.17 11.8 19.0 0.2 11.6 19.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SWI-SNF_Ssr4 PF08549.10 GAM22615.1 - 0.31 9.6 7.8 0.31 9.6 7.8 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Sporozoite_P67 PF05642.11 GAM22615.1 - 0.47 8.5 7.7 0.57 8.2 7.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 GAM22615.1 - 0.6 8.2 21.7 0.73 8.0 21.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 rve PF00665.26 GAM22618.1 - 0.00091 19.4 0.1 0.0014 18.8 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GAM22618.1 - 0.035 14.2 0.2 0.091 12.9 0.2 1.8 1 0 0 1 1 1 0 Integrase zinc binding domain SdrD_B PF17210.3 GAM22619.1 - 6.7e-11 42.4 17.7 1.2e-05 25.5 1.2 3.8 4 0 0 4 4 4 3 SdrD B-like domain SpaA PF17802.1 GAM22619.1 - 5.4 7.4 12.9 37 4.7 2.3 3.7 2 2 0 2 2 2 0 Prealbumin-like fold domain Histone PF00125.24 GAM22621.1 - 6.1e-48 162.5 3.9 7e-48 162.3 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAM22621.1 - 2.9e-05 24.1 0.7 6.7e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAM22621.1 - 3.4e-05 24.1 0.1 6.5e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 GAM22621.1 - 0.00087 19.9 1.3 0.0012 19.5 1.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 GAM22621.1 - 0.034 14.2 0.2 0.068 13.3 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Metallophos PF00149.28 GAM22622.1 - 1.1e-18 68.5 6.9 2.1e-18 67.6 6.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GAM22622.1 - 7.1e-17 61.8 0.5 1.7e-16 60.5 0.5 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 GAM22622.1 - 1.1e-16 61.5 2.3 2.3e-16 60.4 0.6 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 GAM22622.1 - 0.002 18.3 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-RING_2 PF13639.6 GAM22623.1 - 3.7e-10 40.0 9.8 3.7e-10 40.0 9.8 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM22623.1 - 1.7e-09 37.4 9.6 3.5e-09 36.3 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM22623.1 - 4.7e-09 36.0 10.1 1.2e-08 34.7 10.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM22623.1 - 6.3e-07 29.6 7.3 2.1e-06 27.9 7.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAM22623.1 - 1.5e-06 28.0 6.9 1.5e-06 28.0 6.9 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM22623.1 - 2.8e-06 27.3 5.3 7e-06 26.0 5.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAM22623.1 - 4.2e-05 23.3 7.5 0.00012 21.9 7.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAM22623.1 - 0.0018 18.2 9.0 0.0046 16.9 9.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 GAM22623.1 - 0.0037 17.1 2.0 0.0088 15.9 2.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 GAM22623.1 - 0.0052 16.9 9.3 0.014 15.6 9.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 GAM22623.1 - 0.041 13.9 2.9 0.085 12.9 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 GAM22623.1 - 0.32 11.1 5.7 0.86 9.8 5.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-MIZ PF02891.20 GAM22623.1 - 0.81 9.5 7.5 1.5 8.6 7.5 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Clat_adaptor_s PF01217.20 GAM22624.1 - 7.7e-57 191.2 0.7 8.5e-57 191.1 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain 6PF2K PF01591.18 GAM22625.1 - 1.8e-80 269.4 0.0 2.6e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAM22625.1 - 8.2e-36 123.5 0.0 1.2e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAM22625.1 - 1e-05 25.7 0.0 3.2e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AIP3 PF03915.13 GAM22625.1 - 0.0039 16.4 0.2 0.0055 15.8 0.2 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 AAA PF00004.29 GAM22625.1 - 0.12 12.8 0.0 0.62 10.5 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FNIP PF05725.12 GAM22626.1 - 1.2e-21 76.5 4.4 2.1e-06 27.8 0.1 6.0 5 2 1 6 6 6 4 FNIP Repeat LRR_6 PF13516.6 GAM22626.1 - 4.6 7.5 5.6 23 5.4 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeat MFS_1 PF07690.16 GAM22627.1 - 6.9e-29 100.9 20.7 1.3e-27 96.7 5.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 GAM22627.1 - 1.1e-17 63.7 5.1 9.6e-17 60.6 0.3 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Ank_2 PF12796.7 GAM22628.1 - 1.7e-09 38.1 0.4 0.00022 21.8 0.0 3.5 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM22628.1 - 7.7e-05 23.2 0.2 1.6 9.4 0.1 4.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM22628.1 - 0.00023 21.4 0.2 1.3 9.4 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM22628.1 - 0.00098 19.4 0.0 6.4 7.7 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat UPF0052 PF01933.18 GAM22629.1 - 0.0014 18.0 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Ank_2 PF12796.7 GAM22629.1 - 0.0015 19.1 0.3 0.033 14.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM22629.1 - 0.012 16.0 0.4 3.4 8.5 0.1 4.0 3 0 0 3 3 3 0 Ankyrin repeat SWIRM-assoc_2 PF16496.5 GAM22631.1 - 1.3e-58 198.9 0.9 1.3e-58 198.9 0.9 6.9 4 1 3 7 7 7 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 GAM22631.1 - 8.4e-22 77.3 0.6 2.4e-21 75.9 0.6 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 GAM22631.1 - 8.5e-17 60.9 5.1 8.5e-17 60.9 5.1 2.2 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 GAM22631.1 - 4.3e-08 33.2 0.0 7.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM22631.1 - 0.00057 20.1 0.1 0.0018 18.5 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain p450 PF00067.22 GAM22632.1 - 1.1e-82 278.3 0.1 4.8e-61 206.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Es2 PF09751.9 GAM22633.1 - 4.8e-40 138.6 13.5 4.8e-40 138.6 13.5 3.0 2 1 0 2 2 2 1 Nuclear protein Es2 EXS PF03124.14 GAM22634.1 - 8.7e-91 304.7 25.5 1.2e-90 304.2 25.5 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 GAM22634.1 - 1.2e-23 84.7 7.7 1e-11 45.4 2.5 3.2 1 1 2 3 3 3 3 SPX domain McrBC PF10117.9 GAM22634.1 - 0.049 12.8 3.9 0.022 13.9 1.6 1.5 2 0 0 2 2 2 0 McrBC 5-methylcytosine restriction system component DNA_pol_B PF00136.21 GAM22637.1 - 1.3e-97 327.4 1.7 2.4e-97 326.6 1.7 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAM22637.1 - 3.4e-24 85.6 0.2 7.3e-11 41.8 0.1 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GAM22637.1 - 4.3e-15 55.9 6.3 1.3e-14 54.4 6.3 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta zf-UDP PF14569.6 GAM22637.1 - 0.16 12.1 1.2 0.54 10.4 1.1 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger Homeodomain PF00046.29 GAM22638.1 - 0.00015 21.6 1.1 0.00052 19.8 1.1 2.0 1 0 0 1 1 1 1 Homeodomain Pkinase_Tyr PF07714.17 GAM22640.1 - 2e-50 171.5 0.0 3.6e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase COR PF16095.5 GAM22640.1 - 6.2e-48 163.2 0.0 1e-47 162.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Pkinase PF00069.25 GAM22640.1 - 5e-37 127.7 0.0 1.4e-36 126.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Roc PF08477.13 GAM22640.1 - 9.4e-20 71.0 0.1 2.9e-14 53.3 0.0 2.5 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase LRR_4 PF12799.7 GAM22640.1 - 3.3e-14 52.8 23.3 0.00031 21.0 0.5 6.0 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) Ras PF00071.22 GAM22640.1 - 6.1e-10 38.9 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Ras family LRR_8 PF13855.6 GAM22640.1 - 7.8e-10 38.4 6.1 3.1e-09 36.5 1.3 4.8 4 2 1 5 5 5 3 Leucine rich repeat Arf PF00025.21 GAM22640.1 - 0.00042 19.8 0.0 0.02 14.4 0.1 2.6 2 0 0 2 2 2 1 ADP-ribosylation factor family LRR_1 PF00560.33 GAM22640.1 - 0.0017 18.6 11.1 22 6.1 0.1 7.4 6 1 1 7 7 7 0 Leucine Rich Repeat MMR_HSR1 PF01926.23 GAM22640.1 - 0.0022 18.0 0.3 0.0055 16.8 0.3 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAM22640.1 - 0.0049 16.1 0.7 0.01 15.0 0.7 1.5 1 0 0 1 1 1 1 G-protein alpha subunit TniB PF05621.11 GAM22640.1 - 0.026 13.9 0.0 0.062 12.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 GAM22640.1 - 0.15 12.3 0.1 0.4 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain LRR_9 PF14580.6 GAM22640.1 - 0.81 9.2 12.0 0.23 11.0 0.5 3.1 1 1 2 3 3 3 0 Leucine-rich repeat Cytochrom_NNT PF03264.14 GAM22641.1 - 0.028 14.1 0.3 0.033 13.9 0.3 1.1 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region TraK PF06586.11 GAM22641.1 - 0.051 13.3 0.3 0.061 13.0 0.3 1.1 1 0 0 1 1 1 0 TraK protein Nop52 PF05997.12 GAM22642.1 - 1.3e-40 139.6 0.6 1.3e-40 139.6 0.6 1.6 2 0 0 2 2 2 1 Nucleolar protein,Nop52 BUD22 PF09073.10 GAM22642.1 - 0.0043 16.4 5.7 0.0056 16.1 5.7 1.1 1 0 0 1 1 1 1 BUD22 Sigma70_ner PF04546.13 GAM22642.1 - 0.028 14.3 10.1 0.055 13.3 10.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Dicty_REP PF05086.12 GAM22642.1 - 0.041 11.9 7.8 0.068 11.2 7.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nop14 PF04147.12 GAM22642.1 - 0.05 11.8 14.7 0.07 11.3 14.7 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 GAM22642.1 - 0.084 12.4 12.6 0.16 11.5 12.6 1.4 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 GAM22642.1 - 0.15 10.1 14.5 0.23 9.6 14.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi SH3-RhoG_link PF16609.5 GAM22642.1 - 0.3 10.8 3.1 0.51 10.0 3.1 1.3 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region SCIMP PF15050.6 GAM22642.1 - 0.56 10.7 4.4 3.5 8.1 3.8 2.3 2 0 0 2 2 2 0 SCIMP protein YL1 PF05764.13 GAM22642.1 - 1 9.5 13.7 1.9 8.5 13.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein RRN3 PF05327.11 GAM22642.1 - 1.1 7.7 10.9 2.1 6.8 10.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 GAM22642.1 - 1.4 8.2 13.7 2 7.8 13.7 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 GAM22642.1 - 2.1 7.6 13.2 2.9 7.1 13.2 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4589 PF15252.6 GAM22642.1 - 8.3 6.3 8.8 13 5.7 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) WD40 PF00400.32 GAM22643.1 - 2.9e-20 72.2 4.7 8.5e-05 23.3 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM22643.1 - 1.1e-05 25.7 0.0 0.75 10.1 0.0 4.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAM22643.1 - 5.9e-05 22.0 1.1 0.026 13.3 0.3 2.1 1 1 1 2 2 2 2 Nup133 N terminal like PD40 PF07676.12 GAM22643.1 - 0.073 13.0 0.2 1.9 8.5 0.0 3.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF4291 PF14124.6 GAM22644.1 - 2.6e-71 239.2 6.7 3e-71 239.0 6.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Nop PF01798.18 GAM22645.1 - 3.1e-68 229.7 0.1 5.6e-68 228.9 0.1 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 GAM22645.1 - 1.1e-28 100.6 3.7 2.7e-28 99.3 3.7 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain Ank_2 PF12796.7 GAM22646.1 - 9e-27 93.5 11.5 1.9e-08 34.7 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM22646.1 - 3.1e-22 78.4 6.8 0.00077 19.7 0.0 5.7 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM22646.1 - 8e-21 74.1 5.4 8.3e-06 26.3 0.1 5.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM22646.1 - 1.3e-11 43.7 2.6 0.78 10.5 0.0 5.7 5 1 1 6 6 6 4 Ankyrin repeat DUF5049 PF16468.5 GAM22646.1 - 6.5e-08 32.4 0.4 6.4 6.8 0.0 6.3 3 1 4 7 7 7 2 Domain of unknown function (DUF5049) Ank PF00023.30 GAM22646.1 - 0.00037 20.8 0.1 13 6.5 0.0 4.5 4 1 0 4 4 4 1 Ankyrin repeat DUF1843 PF08898.10 GAM22646.1 - 0.003 18.0 2.9 1.8 9.2 0.1 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1843) Sushi_2 PF09014.10 GAM22646.1 - 0.02 14.8 0.1 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain APP_Cu_bd PF12924.7 GAM22646.1 - 0.06 14.1 1.6 32 5.4 0.1 4.0 4 0 0 4 4 4 0 Copper-binding of amyloid precursor, CuBD EnY2 PF10163.9 GAM22647.1 - 2.6e-29 101.4 0.9 3.1e-29 101.2 0.9 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Trans_reg_C PF00486.28 GAM22647.1 - 0.044 13.9 0.1 0.41 10.8 0.0 2.2 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal Beta-lactamase PF00144.24 GAM22647.1 - 0.18 11.0 0.0 0.21 10.8 0.0 1.0 1 0 0 1 1 1 0 Beta-lactamase Kelch_4 PF13418.6 GAM22648.1 - 6.5e-05 22.8 0.2 0.014 15.4 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM22648.1 - 0.0011 19.2 0.0 0.28 11.6 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 GAM22648.1 - 0.0026 18.0 0.4 2.8 8.3 0.1 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM22648.1 - 0.0067 16.4 0.1 0.31 11.1 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 GAM22648.1 - 0.015 14.9 0.4 0.74 9.5 0.1 2.5 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.6 GAM22648.1 - 0.03 14.3 0.1 0.096 12.7 0.1 1.9 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 GAM22649.1 - 3.8e-08 33.4 0.9 5.5e-06 26.5 0.0 2.5 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM22649.1 - 3.3e-07 30.4 0.2 0.0049 17.1 0.0 2.7 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 GAM22649.1 - 9.7e-07 28.3 0.0 4.8e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 GAM22649.1 - 6.4e-06 26.1 0.0 0.04 13.9 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM22649.1 - 9e-06 25.6 0.4 0.023 14.7 0.1 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 GAM22649.1 - 0.026 14.5 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Ribosomal_L35Ae PF01247.18 GAM22650.1 - 2.4e-37 127.0 0.1 2.7e-37 126.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 GAM22650.1 - 0.059 13.6 0.0 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain Sec16_C PF12931.7 GAM22651.1 - 3.3e-10 40.1 0.2 1e-08 35.2 0.2 2.8 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 GAM22651.1 - 8.2e-08 32.8 11.4 0.2 12.6 0.2 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM22651.1 - 0.0054 17.0 1.0 0.37 11.1 0.1 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Sec16 PF12932.7 GAM22651.1 - 0.074 13.7 0.7 0.68 10.5 1.2 2.4 2 1 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region Prp18 PF02840.15 GAM22651.1 - 0.077 13.0 0.1 0.077 13.0 0.1 2.2 2 0 0 2 2 2 0 Prp18 domain LVIVD PF08309.11 GAM22651.1 - 0.26 10.6 1.7 0.64 9.4 0.1 2.4 3 0 0 3 3 3 0 LVIVD repeat CBM49 PF09478.10 GAM22652.1 - 1.6e-17 63.6 0.2 2.1e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 GST_C_3 PF14497.6 GAM22653.1 - 7.6e-19 67.7 0.1 1.6e-18 66.7 0.1 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM22653.1 - 1.3e-10 41.5 0.0 2.2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM22653.1 - 0.00021 21.4 0.1 0.00037 20.7 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM22653.1 - 0.0021 18.4 0.0 0.0045 17.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM22653.1 - 0.0043 17.1 0.0 0.0087 16.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DEAD PF00270.29 GAM22654.1 - 1.6e-44 151.8 1.6 4.4e-44 150.3 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM22654.1 - 1e-30 106.3 3.1 3.9e-30 104.5 0.2 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Ribosomal_60s PF00428.19 GAM22654.1 - 0.032 14.8 0.7 0.077 13.6 0.2 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein AAA_22 PF13401.6 GAM22654.1 - 0.051 13.9 2.5 11 6.3 0.4 3.2 2 2 0 2 2 2 0 AAA domain XRN_M PF17846.1 GAM22654.1 - 0.053 12.5 5.8 0.085 11.8 5.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Copine PF07002.16 GAM22655.1 - 1.1e-61 208.1 0.1 2.3e-61 207.0 0.0 1.5 2 0 0 2 2 2 1 Copine C2 PF00168.30 GAM22655.1 - 3.9e-24 84.9 0.0 5.1e-13 49.2 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 GAM22655.1 - 2.1e-07 31.2 0.0 3.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 GAM22655.1 - 0.00035 20.9 0.1 0.00064 20.0 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1512 PF07431.12 GAM22655.1 - 0.069 12.1 0.7 1 8.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) DUF3871 PF12987.7 GAM22655.1 - 0.07 11.9 0.2 0.27 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3871) Glyco_transf_22 PF03901.17 GAM22656.1 - 1.7e-101 340.5 36.9 2.2e-101 340.2 36.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Secretin_N_2 PF07655.13 GAM22657.1 - 0.019 15.5 24.0 0.28 11.7 7.6 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain PAT1 PF09770.9 GAM22657.1 - 0.17 10.1 34.1 0.21 9.8 34.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YfhO PF09586.10 GAM22657.1 - 4.4 5.4 29.2 5.1 5.2 29.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO HABP4_PAI-RBP1 PF04774.15 GAM22657.1 - 6.2 7.7 16.8 4 8.3 3.6 2.3 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Acetyltransf_2 PF00797.17 GAM22657.1 - 6.9 6.4 15.2 2.4 7.9 8.2 2.2 2 0 0 2 2 2 0 N-acetyltransferase DUF4834 PF16118.5 GAM22657.1 - 9.1 7.3 29.5 0.48 11.4 2.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) UCH PF00443.29 GAM22658.1 - 6e-54 183.2 6.7 6e-54 183.2 6.7 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAM22658.1 - 6.3e-16 58.5 21.7 6.3e-16 58.5 21.7 3.7 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GAM22658.1 - 6.7e-11 42.3 22.8 6.7e-11 42.3 22.8 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Myc_N PF01056.18 GAM22658.1 - 4.9 6.9 12.2 0.25 11.2 4.7 2.4 3 0 0 3 3 3 0 Myc amino-terminal region AMMECR1 PF01871.17 GAM22659.1 - 2.4e-49 167.2 0.0 2.8e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 CBS PF00571.28 GAM22660.1 - 6.6e-08 32.9 0.8 0.002 18.5 0.1 2.6 2 0 0 2 2 2 2 CBS domain DHHA1 PF02272.19 GAM22660.1 - 5.3e-05 23.7 0.0 0.00015 22.2 0.0 1.8 1 0 0 1 1 1 1 DHHA1 domain Gln-synt_C PF00120.24 GAM22661.1 - 3.4e-92 309.1 0.0 4e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 GAM22661.1 - 0.0013 18.5 0.0 0.0036 17.1 0.0 1.7 2 0 0 2 2 2 1 Glutamine synthetase N-terminal domain ubiquitin PF00240.23 GAM22662.1 - 4.6e-09 35.9 0.1 8.2e-09 35.1 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAM22662.1 - 1.3e-06 28.2 0.3 4.5e-06 26.4 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAM22662.1 - 0.00012 22.4 0.1 0.00046 20.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain UN_NPL4 PF11543.8 GAM22662.1 - 0.047 14.2 0.0 0.061 13.8 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Ubiquitin_4 PF18036.1 GAM22662.1 - 0.088 12.9 0.5 0.62 10.2 0.5 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain TOBE_2 PF08402.10 GAM22662.1 - 0.12 12.5 0.0 0.88 9.8 0.0 2.0 2 0 0 2 2 2 0 TOBE domain Porphobil_deam PF01379.20 GAM22663.1 - 1.4e-78 263.1 0.0 1.8e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 GAM22663.1 - 4.9e-21 74.9 0.1 8.9e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF5639 PF18690.1 GAM22663.1 - 0.033 14.4 0.0 0.082 13.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5639) YxiJ PF14176.6 GAM22663.1 - 0.16 12.5 0.0 22 5.6 0.0 2.2 2 0 0 2 2 2 0 YxiJ-like protein Met_synt_B12 PF02965.17 GAM22664.1 - 5.6e-119 396.6 0.0 1.1e-118 395.7 0.0 1.5 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 GAM22664.1 - 1.9e-77 260.7 0.0 4.2e-77 259.6 0.0 1.6 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 GAM22664.1 - 6.7e-57 193.0 1.4 1.3e-56 192.0 0.4 2.1 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 GAM22664.1 - 4.7e-23 81.4 0.1 2.9e-22 78.9 0.0 2.5 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 GAM22664.1 - 3.6e-19 69.0 0.4 7e-18 64.8 0.4 2.9 3 0 0 3 3 3 1 B12 binding domain OKR_DC_1_N PF03709.15 GAM22664.1 - 0.051 13.8 0.3 2 8.7 0.1 3.0 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF4973 PF16343.5 GAM22664.1 - 0.08 13.0 0.3 3.8 7.6 0.3 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4973) SNF2_N PF00176.23 GAM22666.1 - 2.1e-44 151.7 0.7 1.1e-43 149.3 0.3 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM22666.1 - 1.6e-14 54.2 0.0 1.6e-14 54.2 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM22666.1 - 2e-10 40.9 0.1 2e-10 40.9 0.1 4.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 GAM22666.1 - 2.4e-06 26.7 0.3 2.4e-06 26.7 0.3 1.8 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 WD40 PF00400.32 GAM22668.1 - 1.3e-17 63.8 12.9 6e-07 30.1 0.3 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.11 GAM22668.1 - 2.2e-13 50.5 0.3 4.9e-08 33.1 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 GAM22668.1 - 2.8e-12 46.8 1.2 0.032 14.5 0.1 5.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 GAM22668.1 - 0.045 12.1 0.0 0.096 11.0 0.0 1.4 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Alginate_exp PF13372.6 GAM22668.1 - 0.047 12.4 0.0 0.076 11.7 0.0 1.2 1 0 0 1 1 1 0 Alginate export LTV PF04180.14 GAM22669.1 - 1.4e-05 25.0 48.2 0.00053 19.8 10.7 3.7 1 1 2 3 3 3 2 Low temperature viability protein ArfGap PF01412.18 GAM22670.1 - 1.3e-42 144.5 0.2 1.3e-42 144.5 0.2 3.1 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf DDE_3 PF13358.6 GAM22672.1 - 3.1e-23 82.2 0.1 5.1e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease eIF-5_eIF-2B PF01873.17 GAM22672.1 - 0.027 14.3 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain found in IF2B/IF5 TFIIF_alpha PF05793.12 GAM22673.1 - 0.11 11.1 0.2 0.14 10.7 0.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sortilin-Vps10 PF15902.5 GAM22674.1 - 1.6e-57 195.3 3.8 2.3e-57 194.8 3.8 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 GAM22674.1 - 3.8e-28 98.9 1.3 6.1e-28 98.3 1.3 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 GAM22674.1 - 3.3e-08 32.3 13.7 0.23 11.6 0.1 6.4 6 0 0 6 6 6 3 BNR/Asp-box repeat BNR_6 PF15899.5 GAM22674.1 - 4.6e-05 23.1 11.8 2.4 8.4 0.0 5.3 5 0 0 5 5 5 4 BNR-Asp box repeat PH PF00169.29 GAM22675.1 - 3.9e-08 33.7 3.0 3.1e-07 30.9 0.4 3.1 2 1 0 2 2 2 1 PH domain PH_13 PF16652.5 GAM22675.1 - 0.002 18.0 0.5 0.013 15.3 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.6 GAM22675.1 - 0.0045 16.8 0.2 0.021 14.6 0.2 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 GAM22675.1 - 0.026 15.0 0.1 0.086 13.3 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain rve_3 PF13683.6 GAM22675.1 - 0.13 12.1 0.0 6.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Integrase core domain DUF5097 PF17020.5 GAM22675.1 - 0.23 11.8 1.3 9.4 6.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5097) Acyl_transf_1 PF00698.21 GAM22676.1 - 3.2e-26 92.6 0.0 6.1e-26 91.7 0.0 1.4 1 1 0 1 1 1 1 Acyl transferase domain DUF599 PF04654.12 GAM22677.1 - 9.6e-56 188.5 14.4 1.1e-55 188.3 14.4 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 DUF900 PF05990.12 GAM22678.1 - 1.1e-22 80.7 0.1 1.6e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 GAM22678.1 - 0.018 15.7 0.0 0.029 15.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2433 PF10360.9 GAM22679.1 - 0.033 14.3 0.4 1 9.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) Minor_tail_Z PF06763.11 GAM22679.1 - 0.18 11.6 2.1 0.29 10.9 2.1 1.2 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) Img2 PF05046.14 GAM22680.1 - 3.8e-16 59.1 0.0 6.3e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) 2-Hacid_dh_C PF02826.19 GAM22681.1 - 3.3e-53 179.7 0.0 5.1e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAM22681.1 - 3e-23 81.9 0.1 3.5e-23 81.7 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAM22681.1 - 8.5e-07 29.3 0.1 1.6e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 GAM22681.1 - 0.00024 21.2 2.1 0.00066 19.8 1.9 1.8 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DpaA_N PF16924.5 GAM22681.1 - 0.02 14.9 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain IlvN PF07991.12 GAM22681.1 - 0.024 14.2 0.0 0.054 13.1 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox_2 PF07992.14 GAM22681.1 - 0.04 13.2 0.1 0.059 12.6 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 GAM22681.1 - 0.089 13.3 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain DUF383 PF04063.14 GAM22682.1 - 1.2e-36 126.2 1.2 3.5e-36 124.7 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 GAM22682.1 - 1.6e-21 75.9 0.3 5.1e-21 74.3 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.9 GAM22682.1 - 0.0022 16.6 0.3 0.0038 15.8 0.3 1.4 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Symplekin_C PF12295.8 GAM22682.1 - 0.031 14.4 0.1 0.071 13.2 0.1 1.6 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal Cnd1 PF12717.7 GAM22682.1 - 0.052 13.6 0.4 0.052 13.6 0.4 2.1 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.6 GAM22682.1 - 0.058 13.8 0.1 0.31 11.4 0.1 2.2 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 GAM22682.1 - 0.19 12.0 0.6 18 5.7 0.0 3.2 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Pept_tRNA_hydro PF01195.19 GAM22683.1 - 5e-31 108.0 0.0 5.1e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase ELO PF01151.18 GAM22684.1 - 7.9e-61 205.7 25.9 9.2e-61 205.5 25.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Mak16 PF04874.14 GAM22685.1 - 0.0081 16.7 0.0 0.076 13.6 0.0 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region ANAPC4_WD40 PF12894.7 GAM22685.1 - 0.0095 16.2 0.0 0.42 10.9 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-rbx1 PF12678.7 GAM22685.1 - 0.011 16.0 1.2 0.056 13.7 1.2 2.2 1 0 0 1 1 1 0 RING-H2 zinc finger domain WD40_like PF17005.5 GAM22685.1 - 0.015 14.6 0.1 0.035 13.5 0.1 1.5 1 0 0 1 1 1 0 WD40-like domain SUIM_assoc PF16619.5 GAM22685.1 - 0.027 14.5 24.6 0.22 11.6 0.2 5.5 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 zf-RING_11 PF17123.5 GAM22685.1 - 0.028 14.2 1.5 0.089 12.6 1.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger WD40 PF00400.32 GAM22685.1 - 0.068 14.1 0.1 0.69 10.9 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Prok-RING_1 PF14446.6 GAM22685.1 - 0.078 12.9 3.6 0.2 11.6 3.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Clathrin PF00637.20 GAM22685.1 - 0.18 11.7 1.2 1 9.3 0.4 2.3 1 1 1 2 2 2 0 Region in Clathrin and VPS zf-RING_UBOX PF13445.6 GAM22685.1 - 4.2 7.5 8.0 10 6.2 8.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 GAM22685.1 - 4.7 7.6 11.1 0.59 10.5 6.3 2.1 2 0 0 2 2 2 0 Ring finger domain Arf PF00025.21 GAM22686.1 - 1.3e-78 262.4 0.1 1.5e-78 262.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM22686.1 - 4.1e-15 56.1 0.0 5.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM22686.1 - 7.9e-15 54.7 0.0 9.7e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAM22686.1 - 3.4e-14 52.8 2.2 2e-10 40.4 0.7 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GAM22686.1 - 1.1e-12 47.9 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAM22686.1 - 4.7e-12 45.8 0.0 5.8e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM22686.1 - 7.4e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAM22686.1 - 0.009 15.3 0.7 0.027 13.8 0.7 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Peptidase_M8 PF01457.16 GAM22687.1 - 1.8e-52 178.7 0.8 2.5e-52 178.3 0.8 1.1 1 0 0 1 1 1 1 Leishmanolysin ECH_1 PF00378.20 GAM22688.1 - 1.9e-54 184.7 0.0 2.2e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM22688.1 - 6.1e-40 137.7 1.0 1.8e-34 119.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF5382 PF17354.2 GAM22688.1 - 0.19 10.5 0.1 0.32 9.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5382) Abhydrolase_1 PF00561.20 GAM22689.1 - 6.3e-06 26.0 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM22689.1 - 0.00034 20.0 0.0 0.0005 19.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAM22689.1 - 0.00057 19.7 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAM22689.1 - 0.018 15.7 0.0 0.023 15.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 GAM22689.1 - 0.053 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF3089 PF11288.8 GAM22689.1 - 0.088 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) BSD PF03909.17 GAM22691.1 - 4.6e-11 42.6 0.2 4.6e-11 42.6 0.2 2.4 2 0 0 2 2 2 1 BSD domain Cwf_Cwc_15 PF04889.12 GAM22691.1 - 0.087 12.5 9.6 0.18 11.5 9.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DcuA_DcuB PF03605.14 GAM22691.1 - 0.22 10.4 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF902 PF06001.13 GAM22692.1 - 0.055 14.0 3.0 0.12 12.8 3.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) SelR PF01641.18 GAM22693.1 - 2.8e-52 175.9 0.6 3.1e-52 175.7 0.6 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 GAM22693.1 - 0.0031 17.7 1.5 0.0074 16.5 1.5 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 GAM22693.1 - 0.013 15.2 0.5 0.11 12.2 0.1 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Mss51 PF13824.6 GAM22693.1 - 1.1 9.4 5.5 3.4 7.8 0.2 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 RasGEF PF00617.19 GAM22694.1 - 2e-56 191.0 1.7 2e-56 191.0 0.2 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM22694.1 - 1.4e-24 86.3 5.2 2.9e-24 85.3 1.1 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif CDP-OH_P_transf PF01066.21 GAM22695.1 - 1e-16 61.4 0.1 1e-16 61.4 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ORMDL PF04061.14 GAM22696.1 - 1.3e-44 151.3 4.8 1.5e-44 151.1 4.8 1.0 1 0 0 1 1 1 1 ORMDL family DUF2162 PF09930.9 GAM22696.1 - 0.0013 18.2 0.5 0.0015 18.0 0.5 1.1 1 0 0 1 1 1 1 Predicted transporter (DUF2162) Rer1 PF03248.13 GAM22696.1 - 0.011 15.5 2.1 0.23 11.2 0.8 2.2 2 0 0 2 2 2 0 Rer1 family TMEM208_SND2 PF05620.11 GAM22696.1 - 0.084 12.7 2.3 0.14 12.0 2.3 1.4 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 YdjM PF04307.14 GAM22696.1 - 1.1 8.5 7.5 1.5 8.1 7.4 1.3 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase ERO1 PF04137.15 GAM22697.1 - 3.1e-111 372.0 0.5 4.6e-111 371.4 0.5 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RNase_H PF00075.24 GAM22697.1 - 0.017 15.3 0.2 0.045 13.9 0.1 1.8 2 0 0 2 2 2 0 RNase H WAC_Acf1_DNA_bd PF10537.9 GAM22698.1 - 1.2e-27 96.4 1.5 4.2e-27 94.6 1.5 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 GAM22698.1 - 6.4e-17 61.6 2.4 1.6e-16 60.4 2.4 1.7 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 GAM22698.1 - 7.3e-13 48.8 0.9 7.3e-13 48.8 0.9 4.3 2 2 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 GAM22698.1 - 0.0013 18.2 0.0 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 SAP PF02037.27 GAM22699.1 - 5e-12 45.3 0.4 1.3e-11 44.0 0.2 1.8 2 0 0 2 2 2 1 SAP domain Dicty_REP PF05086.12 GAM22699.1 - 0.21 9.5 0.9 0.24 9.4 0.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNA_pol_Rpc4 PF05132.14 GAM22699.1 - 0.38 11.2 3.7 0.53 10.7 3.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zn_Tnp_IS91 PF14319.6 GAM22699.1 - 0.4 10.7 12.2 1.6 8.8 7.5 2.5 1 1 1 2 2 2 0 Transposase zinc-binding domain DUF1178 PF06676.11 GAM22699.1 - 0.93 9.9 4.5 18 5.7 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) HypA PF01155.19 GAM22699.1 - 1.3 9.1 7.9 24 5.0 5.4 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_ligase_ZBD PF03119.16 GAM22699.1 - 9.2 6.4 9.8 1.7 8.8 0.2 2.9 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain TTD PF12148.8 GAM22700.1 - 0.00067 19.6 0.1 0.0017 18.2 0.0 1.6 1 1 1 2 2 2 1 Tandem tudor domain within UHRF1 Agenet PF05641.12 GAM22700.1 - 0.017 15.5 0.0 0.036 14.5 0.0 1.5 1 1 0 1 1 1 0 Agenet domain BetaGal_dom4_5 PF13364.6 GAM22700.1 - 0.018 15.6 0.0 0.027 15.1 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain DUF669 PF05037.13 GAM22700.1 - 0.032 14.4 3.0 3.4 7.8 0.2 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF669) SdrD_B PF17210.3 GAM22702.1 - 1.6e-27 96.0 8.0 3e-12 46.7 0.4 4.3 4 0 0 4 4 4 4 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM22702.1 - 1.5e-08 34.8 0.2 0.19 12.0 0.0 3.7 4 0 0 4 4 4 3 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 GAM22702.1 - 0.0003 20.9 0.1 0.74 9.9 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2012) FlgD_ig PF13860.6 GAM22702.1 - 0.00031 20.6 0.3 1.7 8.6 0.2 3.0 2 1 0 2 2 2 2 FlgD Ig-like domain bMG3 PF11974.8 GAM22702.1 - 0.0013 18.7 0.3 3.6 7.7 0.0 3.8 4 0 0 4 4 4 1 Bacterial alpha-2-macroglobulin MG3 domain SpaA PF17802.1 GAM22702.1 - 0.032 14.5 2.9 13 6.2 2.6 3.1 2 1 0 2 2 2 0 Prealbumin-like fold domain DUF4082 PF13313.6 GAM22702.1 - 0.036 14.1 0.7 2.4 8.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4082) LOR PF04525.12 GAM22702.1 - 0.07 12.7 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 0 LURP-one-related Y_Y_Y PF07495.13 GAM22702.1 - 0.1 12.6 2.8 0.94 9.5 0.1 3.2 3 0 0 3 3 3 0 Y_Y_Y domain WD40 PF00400.32 GAM22704.1 - 2.3e-45 151.7 22.7 6e-08 33.2 0.0 8.1 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 GAM22704.1 - 4.6e-15 55.2 2.6 9.3e-15 54.3 2.6 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 GAM22704.1 - 1.5e-08 34.8 6.5 0.061 13.6 0.1 5.6 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAM22704.1 - 1.8e-08 34.4 0.1 0.5 10.4 0.0 4.6 2 2 1 4 4 4 3 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 GAM22704.1 - 2.8e-08 33.5 1.3 0.002 17.5 0.2 2.6 1 1 1 2 2 2 2 WD40-like domain F-box PF00646.33 GAM22704.1 - 3e-05 23.8 4.3 8.9e-05 22.3 4.3 1.8 1 0 0 1 1 1 1 F-box domain Frtz PF11768.8 GAM22704.1 - 0.00068 18.1 1.8 0.27 9.5 0.0 3.3 1 1 3 4 4 4 3 WD repeat-containing and planar cell polarity effector protein Fritz UbiA PF01040.18 GAM22705.1 - 1.7e-22 80.0 23.4 2.3e-22 79.5 23.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family MBOAT PF03062.19 GAM22706.1 - 1.3e-27 97.1 33.8 1.7e-27 96.7 33.8 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 GAM22706.1 - 0.0039 17.4 6.8 0.0049 17.1 5.0 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Ras PF00071.22 GAM22707.1 - 3.3e-43 147.1 0.7 3.8e-43 146.9 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM22707.1 - 3e-26 92.0 1.2 6e-26 91.0 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM22707.1 - 5.3e-14 52.1 0.2 6.3e-14 51.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM22707.1 - 2e-10 40.4 0.1 2.6e-10 40.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM22707.1 - 1.7e-05 24.9 0.1 2.5e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM22707.1 - 2.5e-05 24.2 1.3 0.013 15.4 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAM22707.1 - 0.00065 19.2 0.0 0.0019 17.7 0.0 1.6 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAM22707.1 - 0.0011 18.5 0.3 0.0022 17.6 0.2 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAM22707.1 - 0.0057 16.2 0.3 0.008 15.7 0.3 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B CPT PF07931.12 GAM22707.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MeaB PF03308.16 GAM22707.1 - 0.025 13.6 0.2 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAM22707.1 - 0.097 13.1 0.2 0.34 11.3 0.3 1.9 1 1 1 2 2 2 0 AAA ATPase domain ICL PF00463.21 GAM22708.1 - 1.9e-104 350.1 1.9 6.5e-55 186.6 0.1 2.1 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 GAM22708.1 - 6.2e-16 58.6 0.0 9.2e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pkinase PF00069.25 GAM22709.1 - 4e-60 203.4 0.1 1.2e-59 201.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22709.1 - 9.8e-23 80.7 0.0 1.8e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM22709.1 - 9.2e-08 31.7 0.0 3.4e-07 29.9 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 GAM22709.1 - 0.047 13.0 0.1 0.094 12.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAM22709.1 - 0.27 10.9 2.4 1.5 8.4 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Ndc1_Nup PF09531.10 GAM22709.1 - 0.7 8.5 7.0 0.98 8.0 7.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Porin_3 PF01459.22 GAM22710.1 - 8.2e-24 84.5 2.9 3.5e-19 69.3 0.2 2.0 2 0 0 2 2 2 2 Eukaryotic porin STATa_Ig PF18214.1 GAM22711.1 - 0.0001 22.3 0.5 0.0002 21.4 0.5 1.5 1 0 0 1 1 1 1 STATa Immunoglobulin-like domain RasGAP PF00616.19 GAM22712.1 - 5.5e-36 124.2 0.1 3.4e-22 79.2 0.0 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 GAM22712.1 - 1.5e-21 76.6 0.0 4.8e-21 75.0 0.0 1.9 2 0 0 2 2 2 1 C2 domain Vitellogenin_N PF01347.22 GAM22712.1 - 0.047 12.1 0.0 0.053 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region SSP160 PF06933.11 GAM22712.1 - 1.6 6.9 6.1 2.3 6.3 6.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RtcB PF01139.17 GAM22713.1 - 9.3e-149 496.1 0.0 1.1e-148 495.9 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB AAA PF00004.29 GAM22715.1 - 1.4e-40 138.7 0.3 2.4e-38 131.6 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM22715.1 - 8.8e-11 41.4 0.2 3.2e-10 39.7 0.2 2.0 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 GAM22715.1 - 4.5e-06 26.5 0.0 6.1e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 GAM22715.1 - 1.5e-05 24.9 0.3 5e-05 23.2 0.3 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 GAM22715.1 - 0.00011 22.1 0.2 0.0097 15.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAM22715.1 - 0.00019 21.7 1.6 0.014 15.7 0.1 3.3 3 1 0 4 4 2 1 AAA domain AAA_2 PF07724.14 GAM22715.1 - 0.00032 20.9 0.0 0.012 15.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAM22715.1 - 0.00045 20.6 1.5 0.056 13.8 0.0 4.1 4 1 0 5 5 5 1 AAA ATPase domain AAA_5 PF07728.14 GAM22715.1 - 0.00065 19.7 0.1 0.012 15.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAM22715.1 - 0.0022 17.8 0.0 0.0065 16.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAM22715.1 - 0.0026 17.2 0.7 0.012 15.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GAM22715.1 - 0.0028 17.7 0.0 0.017 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 GAM22715.1 - 0.0028 16.9 0.5 0.01 15.1 0.1 2.0 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 GAM22715.1 - 0.003 17.7 0.1 0.021 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM22715.1 - 0.014 15.9 0.0 0.039 14.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 GAM22715.1 - 0.015 15.0 1.6 4.9 6.8 0.0 4.1 4 0 0 4 4 4 0 Guanylate kinase AAA_7 PF12775.7 GAM22715.1 - 0.025 14.1 0.1 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 GAM22715.1 - 0.038 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein TniB PF05621.11 GAM22715.1 - 0.052 13.0 0.0 14 5.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 GAM22715.1 - 0.057 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GAM22715.1 - 0.084 13.3 0.0 0.35 11.3 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 GAM22715.1 - 0.094 13.0 0.3 0.37 11.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAM22715.1 - 0.12 12.1 0.1 0.38 10.4 0.1 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain DHR-2 PF06920.13 GAM22716.1 - 8.7e-86 288.6 14.9 8.7e-86 288.6 14.9 2.2 2 1 0 2 2 2 1 Dock homology region 2 DOCK_N PF16172.5 GAM22716.1 - 9.2e-58 196.0 2.3 3.7e-57 193.9 0.0 3.1 4 0 0 4 4 4 1 DOCK N-terminus DOCK-C2 PF14429.6 GAM22716.1 - 6.3e-43 146.9 3.6 6e-41 140.4 1.3 3.2 3 0 0 3 3 3 2 C2 domain in Dock180 and Zizimin proteins WD40 PF00400.32 GAM22717.1 - 9.5e-11 42.1 5.7 0.6 11.1 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat His_Phos_1 PF00300.22 GAM22718.1 - 6.5e-35 120.6 0.0 1.1e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pro_isomerase PF00160.21 GAM22718.1 - 2e-13 50.9 0.0 2.2e-12 47.5 0.0 2.2 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Macoilin PF09726.9 GAM22719.1 - 0.022 13.3 3.3 0.024 13.2 3.3 1.1 1 0 0 1 1 1 0 Macoilin family CENP-L PF13092.6 GAM22719.1 - 0.14 12.4 0.6 0.18 12.0 0.6 1.4 1 1 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 UPF0449 PF15136.6 GAM22719.1 - 1.8 9.1 6.8 1.2 9.7 1.5 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 FF PF01846.19 GAM22720.1 - 5.7e-42 141.7 22.6 1.4e-09 38.0 0.4 6.8 6 0 0 6 6 6 6 FF domain WW PF00397.26 GAM22720.1 - 1.6e-20 72.8 12.6 1.5e-11 44.2 2.8 2.9 2 0 0 2 2 2 2 WW domain Lipase_GDSL_2 PF13472.6 GAM22720.1 - 0.16 12.4 0.0 1.5 9.2 0.0 2.4 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Pet127 PF08634.10 GAM22721.1 - 7.5e-85 284.7 2.9 1.1e-84 284.2 2.9 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 COX4 PF02936.14 GAM22722.1 - 0.014 15.4 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV ATP-synt_F PF01990.17 GAM22723.1 - 1.4e-30 105.4 0.6 1.7e-30 105.1 0.6 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit LPAM_2 PF13627.6 GAM22723.1 - 0.011 15.5 0.7 0.019 14.8 0.7 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DXP_synthase_N PF13292.6 GAM22723.1 - 0.046 12.9 0.1 0.051 12.8 0.1 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DSPc PF00782.20 GAM22724.1 - 3.5e-30 104.5 0.0 6.1e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM22724.1 - 0.00097 18.8 0.1 0.0021 17.6 0.1 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 GAM22724.1 - 0.044 13.4 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) EIF_2_alpha PF07541.12 GAM22725.1 - 1.6e-35 121.7 0.0 3.2e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 GAM22725.1 - 1e-11 45.0 2.0 1.9e-11 44.1 2.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain EXS PF03124.14 GAM22726.1 - 2.3e-67 227.7 38.6 3.3e-67 227.1 38.6 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 GAM22726.1 - 6.2e-23 82.3 3.3 1.3e-10 41.8 0.0 3.1 1 1 2 3 3 3 3 SPX domain DEAD PF00270.29 GAM22727.1 - 2.6e-17 63.2 0.0 2.6e-17 63.2 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM22727.1 - 1.2e-16 61.1 0.0 1.2e-16 61.1 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM22727.1 - 2.3e-05 24.7 0.0 0.00012 22.3 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SAM_3 PF18016.1 GAM22727.1 - 0.025 14.4 0.1 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DDHD PF02862.17 GAM22727.1 - 2.9 8.0 12.0 8.3 6.5 8.1 3.2 3 0 0 3 3 3 0 DDHD domain C12orf66_like PF09404.10 GAM22728.1 - 7.6e-46 156.8 6.4 7.4e-37 127.2 0.7 2.2 2 0 0 2 2 2 2 KICSTOR complex C12orf66 like MBD_C PF14048.6 GAM22728.1 - 0.33 11.7 2.5 2.5 8.9 0.5 2.3 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 CH PF00307.31 GAM22729.1 - 1e-14 54.6 0.1 3.8e-14 52.8 0.0 2.1 2 0 0 2 2 1 1 Calponin homology (CH) domain SBF2 PF12335.8 GAM22729.1 - 3.2e-09 36.8 0.1 3.2e-09 36.8 0.1 2.8 3 0 0 3 3 2 1 Myotubularin protein zinc_ribbon_2 PF13240.6 GAM22729.1 - 2.2e-05 24.0 8.3 0.00055 19.6 3.6 2.7 2 0 0 2 2 2 1 zinc-ribbon domain Atg14 PF10186.9 GAM22729.1 - 0.00033 19.9 16.4 0.00073 18.7 0.9 2.5 3 0 0 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 APG17 PF04108.12 GAM22729.1 - 0.00066 18.9 4.5 0.00066 18.9 4.5 2.5 3 0 0 3 3 2 1 Autophagy protein Apg17 DZR PF12773.7 GAM22729.1 - 0.0013 18.7 9.7 0.0099 15.9 1.5 2.5 2 0 0 2 2 2 1 Double zinc ribbon Lipoprotein_7 PF01540.16 GAM22729.1 - 0.0021 17.4 0.1 0.0021 17.4 0.1 2.4 2 0 0 2 2 2 1 Adhesin lipoprotein Vps23_core PF09454.10 GAM22729.1 - 0.0022 17.9 1.3 0.0082 16.1 0.6 2.2 2 0 0 2 2 2 1 Vps23 core domain LRRFIP PF09738.9 GAM22729.1 - 0.0032 17.0 2.8 0.0032 17.0 2.8 2.8 2 1 0 2 2 1 1 LRRFIP family CENP-Q PF13094.6 GAM22729.1 - 0.0091 16.2 2.0 0.0091 16.2 2.0 3.0 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Exonuc_VII_L PF02601.15 GAM22729.1 - 0.0097 15.5 16.0 0.049 13.2 1.5 2.8 3 0 0 3 3 3 2 Exonuclease VII, large subunit CDC24 PF06395.11 GAM22729.1 - 0.012 15.8 0.1 0.14 12.4 0.0 2.6 2 0 0 2 2 2 0 CDC24 Calponin CAMSAP_CH PF11971.8 GAM22729.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain zinc_ribbon_15 PF17032.5 GAM22729.1 - 0.022 15.5 3.9 0.025 15.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon family DGF-1_C PF11040.8 GAM22729.1 - 0.091 12.8 0.1 0.43 10.6 0.1 2.2 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Pedibin PF08182.11 GAM22729.1 - 0.14 12.0 2.9 4.6 7.1 0.4 3.1 2 0 0 2 2 2 0 Pedibin/Hym-346 family ADIP PF11559.8 GAM22729.1 - 1.6 8.8 38.6 6.3 6.9 9.9 3.5 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 GAM22729.1 - 2.1 6.8 16.4 0.68 8.5 4.4 2.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A SlyX PF04102.12 GAM22729.1 - 2.2 9.0 31.4 9 7.0 9.4 4.6 3 1 0 3 3 3 0 SlyX GAS PF13851.6 GAM22729.1 - 2.2 7.6 34.1 0.14 11.5 9.7 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding PocR PF10114.9 GAM22729.1 - 2.3 8.0 4.3 3.9 7.2 0.3 2.7 2 0 0 2 2 2 0 Sensory domain found in PocR DUF1664 PF07889.12 GAM22729.1 - 3 7.9 27.0 9 6.4 8.7 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FliD_C PF07195.12 GAM22729.1 - 3 7.2 19.9 0.2 11.0 4.3 2.6 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 C-terminus Phage_GPO PF05929.11 GAM22729.1 - 3.1 7.4 17.9 0.028 14.1 1.1 2.9 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4718 PF15842.5 GAM22729.1 - 3.9 7.2 9.1 4.6 7.0 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) NOB1_Zn_bind PF08772.11 GAM22729.1 - 3.9 7.7 9.0 0.93 9.7 1.1 2.7 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Lebercilin PF15619.6 GAM22729.1 - 4.1 7.0 41.8 0.35 10.5 14.4 3.3 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Striatin PF08232.12 GAM22729.1 - 4.4 7.9 19.9 2.1 9.0 5.7 3.4 3 0 0 3 3 3 0 Striatin family HMMR_N PF15905.5 GAM22729.1 - 4.8 6.6 39.5 0.21 11.0 12.6 2.6 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 GAM22729.1 - 7 6.8 32.3 0.4 10.9 6.7 3.2 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 GAM22729.1 - 7.2 6.5 14.6 5.7 6.9 3.3 4.0 2 1 2 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Kelch_4 PF13418.6 GAM22730.1 - 1.1e-13 50.9 7.3 0.0012 18.8 0.0 5.1 4 2 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM22730.1 - 1.3e-13 50.7 14.5 6.9e-06 26.2 0.1 4.9 4 2 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAM22730.1 - 7.9e-13 47.8 8.1 7.9e-06 25.4 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 GAM22730.1 - 2e-06 27.9 4.4 0.073 13.4 0.0 5.2 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM22730.1 - 1.1e-05 25.3 7.9 0.015 15.3 0.8 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAM22730.1 - 4.8e-05 23.2 8.2 0.027 14.5 0.6 4.0 4 0 0 4 4 4 2 Kelch motif Sec23_trunk PF04811.15 GAM22731.1 - 1.3e-43 149.3 0.0 2.2e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAM22731.1 - 5.7e-19 67.8 0.1 1.5e-18 66.5 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAM22731.1 - 7.7e-16 58.6 0.0 2.1e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAM22731.1 - 5.3e-14 52.0 4.6 1.1e-13 51.0 4.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAM22731.1 - 1.4e-05 24.9 0.0 6.1e-05 22.8 0.0 2.1 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L4 PF00573.22 GAM22732.1 - 4.7e-37 127.5 0.1 7.8e-37 126.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 GAM22732.1 - 3.6e-23 81.4 3.7 5.4e-22 77.7 3.2 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Cnd1 PF12717.7 GAM22734.1 - 0.045 13.8 2.2 0.091 12.8 0.2 2.1 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Ras PF00071.22 GAM22735.1 - 0.014 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Ras family RHS_repeat PF05593.14 GAM22736.1 - 1.2e-23 83.2 52.3 4.3e-05 23.9 0.1 15.1 12 3 3 15 15 15 12 RHS Repeat Aldedh PF00171.22 GAM22737.1 - 4.4e-130 434.3 0.2 5.2e-130 434.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Arena_RNA_pol PF06317.11 GAM22737.1 - 0.18 9.0 0.2 0.24 8.5 0.2 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Senescence PF06911.12 GAM22738.1 - 9.4e-29 101.0 6.5 9.4e-29 101.0 6.5 1.9 2 0 0 2 2 2 1 Senescence-associated protein PH PF00169.29 GAM22738.1 - 5.1e-09 36.6 0.2 2.1e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 PH domain PDEase_I PF00233.19 GAM22739.1 - 1.8e-86 289.8 8.0 1.8e-86 289.8 8.0 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 GAM22739.1 - 8.7e-26 90.3 0.8 1.9e-25 89.2 0.8 1.6 1 0 0 1 1 1 1 Response regulator receiver domain IlvC PF01450.19 GAM22739.1 - 0.047 14.0 0.4 0.095 13.0 0.4 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain FtsJ PF01728.19 GAM22739.1 - 0.11 12.6 0.1 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase FNIP PF05725.12 GAM22740.1 - 1.9e-56 188.0 36.1 1.8e-13 50.4 0.2 9.7 6 2 4 10 10 10 9 FNIP Repeat Pam16 PF03656.13 GAM22741.1 - 2.7e-16 59.7 0.0 3.2e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Pam16 DNA_binding_1 PF01035.20 GAM22742.1 - 1.3e-25 89.4 0.0 1.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 GAM22742.1 - 0.011 16.5 0.0 0.1 13.4 0.0 2.2 1 1 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Proteasom_Rpn13 PF04683.13 GAM22743.1 - 1.1e-19 70.7 0.2 1.3e-19 70.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor FNIP PF05725.12 GAM22744.1 - 7.2e-40 134.9 9.2 1.6e-11 44.2 0.1 5.4 2 1 3 6 6 6 6 FNIP Repeat DUF1769 PF08588.10 GAM22744.1 - 0.016 15.4 3.1 29 4.9 0.0 4.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1769) RCC1 PF00415.18 GAM22745.1 - 1.9e-85 281.3 19.0 3.2e-14 53.3 0.4 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM22745.1 - 3.5e-44 147.8 29.8 6.5e-08 32.2 0.2 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 GAM22745.1 - 1.4e-23 83.2 5.1 1.2e-14 54.5 0.3 3.1 3 0 0 3 3 3 2 BTB/POZ domain RPAP1_N PF08621.10 GAM22745.1 - 0.16 11.8 0.0 0.7 9.7 0.0 2.1 1 0 0 1 1 1 0 RPAP1-like, N-terminal DUF4213 PF13938.6 GAM22745.1 - 5.4 7.3 5.4 2.7 8.3 0.1 3.1 4 1 1 5 5 5 0 Putative heavy-metal chelation CH PF00307.31 GAM22746.1 - 2.7e-15 56.5 0.1 6.1e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 GAM22746.1 - 0.12 12.7 0.3 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 CDC24 Calponin Utp14 PF04615.13 GAM22746.1 - 0.18 10.3 7.4 0.25 9.9 7.4 1.3 1 0 0 1 1 1 0 Utp14 protein vATP-synt_AC39 PF01992.16 GAM22748.1 - 8.1e-117 390.5 0.6 9.1e-117 390.3 0.6 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Sec62 PF03839.16 GAM22749.1 - 0.00084 18.9 7.1 0.0015 18.1 3.0 2.2 2 0 0 2 2 2 1 Translocation protein Sec62 Pkr1 PF08636.10 GAM22749.1 - 0.004 17.3 2.0 0.0064 16.6 2.0 1.3 1 0 0 1 1 1 1 ER protein Pkr1 DUF4813 PF16072.5 GAM22749.1 - 1.3 8.7 19.3 1.4 8.6 7.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) PA26 PF04636.13 GAM22749.1 - 1.8 7.4 6.1 2.5 6.9 6.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GREB1 PF15782.5 GAM22749.1 - 5.5 4.0 16.2 6.9 3.6 16.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 GAM22749.1 - 5.6 6.8 29.0 7.8 6.4 29.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SdrD_B PF17210.3 GAM22750.1 - 7.1e-92 303.2 157.5 1.4e-10 41.4 0.8 16.4 14 2 3 17 17 17 12 SdrD B-like domain DUF2012 PF09430.10 GAM22750.1 - 1.4e-11 44.5 0.0 14 5.8 0.0 10.9 12 0 0 12 12 12 2 Protein of unknown function (DUF2012) GP17 PF17420.2 GAM22750.1 - 1.2e-06 28.6 10.2 22 5.3 0.0 8.4 9 0 0 9 9 9 2 Superinfection exclusion gene product 17 Y_Y_Y PF07495.13 GAM22750.1 - 0.0051 16.7 12.2 3.2 7.8 0.1 6.9 7 0 0 7 7 7 2 Y_Y_Y domain Inh PF02974.14 GAM22750.1 - 0.098 12.7 11.3 76 3.5 0.0 7.6 9 0 0 9 9 9 0 Protease inhibitor Inh DUF1769 PF08588.10 GAM22750.1 - 0.65 10.2 6.8 12 6.2 0.1 5.5 7 0 0 7 7 7 0 Protein of unknown function (DUF1769) MazG_C PF18722.1 GAM22750.1 - 0.75 9.3 12.8 89 2.5 0.0 6.1 6 0 0 6 6 6 0 MazG C-terminal domain SdrD_B PF17210.3 GAM22751.1 - 3.2e-70 233.5 53.1 1.1e-11 45.0 2.6 7.3 7 0 0 7 7 7 7 SdrD B-like domain SpaA PF17802.1 GAM22751.1 - 4.5e-15 55.7 31.1 0.067 13.5 0.1 7.5 7 0 0 7 7 7 7 Prealbumin-like fold domain DUF2012 PF09430.10 GAM22751.1 - 7.8e-07 29.3 0.0 6.3 6.9 0.0 6.0 7 0 0 7 7 7 2 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 GAM22751.1 - 6.2e-06 26.4 9.5 19 5.6 0.0 8.5 8 0 0 8 8 8 1 Carboxypeptidase regulatory-like domain GP17 PF17420.2 GAM22751.1 - 1.5e-05 25.1 10.9 7.7 6.8 0.0 6.9 7 0 0 7 7 7 2 Superinfection exclusion gene product 17 MazG_C PF18722.1 GAM22751.1 - 0.0024 17.4 2.0 6 6.3 0.0 4.2 4 0 0 4 4 4 1 MazG C-terminal domain Y_Y_Y PF07495.13 GAM22751.1 - 0.095 12.7 13.8 1.3 9.1 0.1 7.0 9 0 0 9 9 9 0 Y_Y_Y domain Inh PF02974.14 GAM22751.1 - 1.3 9.2 5.0 31 4.7 0.0 4.6 5 0 0 5 5 5 0 Protease inhibitor Inh Peptidase_M24 PF00557.24 GAM22752.1 - 5e-56 189.7 0.0 6.8e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAM22752.1 - 7.7e-34 116.1 0.0 1.2e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 GAM22752.1 - 0.087 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) HTH_37 PF13744.6 GAM22752.1 - 0.096 12.7 0.3 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain PNTB PF02233.16 GAM22753.1 - 1.9e-176 587.6 21.6 1.9e-176 587.6 21.6 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 GAM22753.1 - 2.8e-74 249.0 1.0 5.9e-74 248.0 1.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 GAM22753.1 - 3.2e-45 153.8 0.1 6.3e-45 152.8 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 GAM22753.1 - 1.1e-30 105.8 4.9 1.1e-30 105.8 4.9 3.7 3 1 1 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 GAM22753.1 - 0.00066 19.1 3.1 0.1 12.0 0.1 3.5 4 0 0 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 GAM22753.1 - 0.032 14.2 0.1 0.33 11.0 0.2 2.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase F420_oxidored PF03807.17 GAM22753.1 - 0.12 13.0 2.8 0.32 11.6 0.0 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF3392 PF11872.8 GAM22753.1 - 0.42 10.9 2.3 0.65 10.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) Ribosomal_S6e PF01092.19 GAM22754.1 - 6.2e-53 178.1 0.0 1.1e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Herpes_BLLF1 PF05109.13 GAM22754.1 - 2.8 5.8 9.2 3.6 5.5 9.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) AAR2 PF05282.11 GAM22755.1 - 5e-97 325.5 0.2 7e-97 325.0 0.2 1.2 1 0 0 1 1 1 1 AAR2 protein Androgen_recep PF02166.16 GAM22755.1 - 0.72 8.6 3.1 1.4 7.7 3.1 1.4 1 0 0 1 1 1 0 Androgen receptor DUF2043 PF09740.9 GAM22756.1 - 1.2e-25 90.3 0.0 3.7e-25 88.7 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2043) SSP160 PF06933.11 GAM22756.1 - 0.25 9.5 1.3 0.36 9.0 1.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ank_2 PF12796.7 GAM22757.1 - 8.2e-05 23.1 0.1 0.0018 18.8 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM22757.1 - 0.0075 16.7 0.5 2.7 8.9 0.1 4.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 GAM22757.1 - 0.0097 16.5 0.2 0.094 13.3 0.1 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) 7tm_2 PF00002.24 GAM22761.1 - 6.1e-07 29.0 19.7 6.5e-07 28.9 18.5 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 GAM22761.1 - 0.0012 18.9 1.4 0.0012 18.9 1.4 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Frizzled PF01534.17 GAM22761.1 - 0.003 16.7 13.3 0.0046 16.0 13.3 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region PH PF00169.29 GAM22762.1 - 4e-18 65.8 0.2 5.7e-18 65.3 0.2 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM22762.1 - 4.4e-05 23.7 0.0 6.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAM22762.1 - 0.00014 22.2 3.4 0.005 17.2 3.4 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 GAM22762.1 - 0.0018 18.6 0.2 0.013 15.9 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 GAM22762.1 - 0.016 15.5 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain IML1 PF12257.8 GAM22764.1 - 1.2e-110 369.1 0.1 1.9e-110 368.5 0.1 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 GAM22764.1 - 5.6e-18 64.8 0.3 1.7e-17 63.2 0.3 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGEF PF00621.20 GAM22765.1 - 1.7e-38 132.7 1.5 1.9e-37 129.2 0.1 2.5 2 0 0 2 2 2 1 RhoGEF domain Synaptobrevin PF00957.21 GAM22766.1 - 6.9e-31 105.9 3.5 1e-30 105.4 3.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAM22766.1 - 5.3e-24 84.1 0.0 9.1e-24 83.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RhoGEF PF00621.20 GAM22767.1 - 1.5e-16 61.1 0.1 1.8e-16 60.9 0.1 1.0 1 0 0 1 1 1 1 RhoGEF domain Gag_p30 PF02093.16 GAM22767.1 - 0.065 12.8 0.0 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 Gag P30 core shell protein EcoEI_R_C PF08463.10 GAM22767.1 - 0.084 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal CBP_BcsF PF11120.8 GAM22768.1 - 1 9.5 5.2 0.41 10.8 0.8 2.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF Lactamase_B_2 PF12706.7 GAM22769.1 - 4e-21 75.4 0.0 8.8e-19 67.8 0.1 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 GAM22769.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 GAM22769.1 - 0.002 18.2 0.9 0.015 15.3 0.8 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily FH2 PF02181.23 GAM22770.1 - 1e-80 271.7 0.3 1e-80 271.7 0.3 2.9 3 0 0 3 3 3 1 Formin Homology 2 Domain DUF3361 PF11841.8 GAM22770.1 - 1.8e-06 27.9 0.0 7.4e-06 26.0 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Drf_FH3 PF06367.16 GAM22770.1 - 0.0011 18.7 1.8 0.0011 18.7 1.8 2.7 3 1 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 GAM22770.1 - 0.27 10.8 5.1 0.31 10.6 0.0 3.2 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain SOAR PF16533.5 GAM22770.1 - 0.53 10.3 5.6 0.54 10.3 2.0 2.6 2 0 0 2 2 2 0 STIM1 Orai1-activating region FlaC_arch PF05377.11 GAM22770.1 - 3.6 8.1 7.8 1.1e+02 3.4 0.0 5.0 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) SdrD_B PF17210.3 GAM22771.1 - 0.0064 16.7 0.5 0.024 14.9 0.1 2.0 2 0 0 2 2 2 1 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM22771.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain AAA_5 PF07728.14 GAM22771.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Kelch_6 PF13964.6 GAM22772.1 - 2.4e-10 40.3 3.9 3.2e-06 27.2 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 GAM22772.1 - 1.6e-09 37.2 2.9 2.2e-06 27.1 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 GAM22772.1 - 1.5e-05 24.9 6.4 0.012 15.6 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM22772.1 - 1.6e-05 24.7 1.6 0.044 13.8 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 GAM22772.1 - 0.00017 21.8 0.4 0.53 10.6 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM22772.1 - 0.0032 17.4 8.5 0.32 11.0 1.1 3.1 3 0 0 3 3 3 2 Kelch motif Disulph_isomer PF06491.11 GAM22772.1 - 0.041 14.0 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Disulphide isomerase RPN5_C PF18098.1 GAM22772.1 - 0.14 12.2 2.2 0.38 10.9 2.2 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain THOC7 PF05615.13 GAM22773.1 - 4.4e-24 85.2 4.3 4.4e-24 85.2 4.3 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 Glu-tRNAGln PF02686.15 GAM22773.1 - 0.027 14.8 2.7 1.4 9.3 0.1 3.1 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit SOAR PF16533.5 GAM22773.1 - 0.16 12.0 4.4 0.44 10.5 0.4 2.7 1 1 1 2 2 2 0 STIM1 Orai1-activating region Tup_N PF08581.10 GAM22773.1 - 0.3 11.4 13.6 0.14 12.5 3.0 2.4 2 0 0 2 2 2 0 Tup N-terminal Zwint PF15556.6 GAM22773.1 - 0.35 10.3 11.1 0.071 12.6 3.3 2.3 1 1 1 2 2 2 0 ZW10 interactor Jnk-SapK_ap_N PF09744.9 GAM22773.1 - 0.86 9.8 13.9 0.49 10.6 10.8 2.0 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 GAM22773.1 - 4.2 7.9 16.7 1.2e+03 0.0 16.7 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Csm1_N PF18504.1 GAM22773.1 - 5 7.5 12.8 3.8 7.9 1.0 3.3 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF3430 PF11912.8 GAM22774.1 - 7.8e-20 71.8 12.0 9.7e-20 71.5 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Fer4 PF00037.27 GAM22775.1 - 1.1e-14 53.6 16.9 9.8e-09 34.7 5.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 GAM22775.1 - 6e-13 49.2 10.8 9.2e-13 48.6 10.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 GAM22775.1 - 1.3e-10 42.1 6.6 3.2e-05 24.8 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 GAM22775.1 - 7e-10 38.9 22.2 7.8e-07 29.1 13.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 GAM22775.1 - 9.3e-10 38.5 4.4 0.00012 22.1 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAM22775.1 - 5e-09 36.2 10.7 8.4e-09 35.5 10.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAM22775.1 - 3.9e-07 29.9 18.2 0.00036 20.5 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 GAM22775.1 - 1.3e-06 28.7 21.1 0.00025 21.5 12.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 GAM22775.1 - 1.4e-06 28.0 12.8 0.0027 17.7 2.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 GAM22775.1 - 2.1e-05 24.7 11.5 0.00033 20.9 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 GAM22775.1 - 0.00049 20.6 12.7 0.037 14.6 13.7 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 GAM22775.1 - 0.01 16.4 15.0 0.44 11.1 2.9 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 GAM22775.1 - 0.01 16.0 8.4 0.46 10.7 0.8 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 GAM22775.1 - 0.037 14.2 6.5 1.1 9.5 0.4 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.7 GAM22775.1 - 0.052 14.5 16.5 0.09 13.8 4.3 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 GAM22775.1 - 0.31 11.2 6.0 1.8 8.7 0.7 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 GAM22775.1 - 0.44 11.4 11.7 1.7 9.5 1.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain LRR_4 PF12799.7 GAM22776.1 - 1.9e-06 28.1 29.8 0.094 13.2 3.7 7.2 5 2 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM22776.1 - 1.3 8.8 26.4 6.2 6.7 0.1 7.1 5 1 0 6 6 6 0 Leucine rich repeat TPR_2 PF07719.17 GAM22777.1 - 1.3e-05 25.0 5.7 0.0094 16.0 0.3 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM22777.1 - 0.00021 21.9 1.8 0.35 11.8 0.1 4.3 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM22777.1 - 0.00039 20.1 2.8 0.32 10.9 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM22777.1 - 0.00085 19.3 2.0 0.078 13.2 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM22777.1 - 0.0016 18.9 2.6 0.1 13.1 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM22777.1 - 0.0026 18.0 1.7 3.1 8.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF5588 PF17826.1 GAM22777.1 - 0.11 11.3 0.3 0.6 8.9 0.3 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5588) TPR_7 PF13176.6 GAM22777.1 - 0.19 11.8 1.8 7.2 6.9 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM22777.1 - 4.7 8.1 6.9 12 6.8 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RasGEF PF00617.19 GAM22778.1 - 1.2e-58 198.2 6.1 1.5e-58 197.9 2.5 2.4 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM22778.1 - 1.4e-23 83.1 0.2 7.8e-23 80.7 0.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif DUF3501 PF12007.8 GAM22778.1 - 0.0065 16.5 0.9 0.033 14.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3501) LisH_TPL PF17814.1 GAM22778.1 - 0.073 12.7 0.2 0.073 12.7 0.2 2.8 3 0 0 3 3 3 0 LisH-like dimerisation domain AAA_lid_11 PF18198.1 GAM22778.1 - 0.073 12.9 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain TIG PF01833.24 GAM22779.1 - 7.5e-21 74.0 24.3 8.1e-10 38.6 0.3 4.6 3 1 1 4 4 4 4 IPT/TIG domain OST_IS PF18246.1 GAM22779.1 - 0.058 13.7 2.3 5.3 7.4 0.1 4.2 5 0 0 5 5 5 0 Oligosaccharyltransferase Insert domain GATA PF00320.27 GAM22780.1 - 3.2e-13 49.0 6.0 5.6e-13 48.2 6.0 1.4 1 0 0 1 1 1 1 GATA zinc finger PRESAN PF09687.10 GAM22780.1 - 0.15 12.6 0.1 0.28 11.7 0.1 1.4 1 0 0 1 1 1 0 Plasmodium RESA N-terminal DUF3923 PF13061.6 GAM22782.1 - 0.8 9.8 13.9 0.39 10.8 9.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3923) DUF5090 PF17009.5 GAM22782.1 - 7.5 6.5 12.9 7.8 6.4 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DOT1 PF08123.13 GAM22783.1 - 1.6e-29 102.9 0.0 2.8e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 GAM22783.1 - 1.7e-05 25.4 0.2 6.8e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM22783.1 - 0.023 14.5 1.3 0.087 12.7 1.3 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAM22783.1 - 0.03 14.1 1.0 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAM22783.1 - 0.03 15.0 0.5 0.077 13.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAM22783.1 - 0.41 11.4 2.7 1.1 10.0 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain DUF4820 PF16091.5 GAM22783.1 - 6.7 6.0 11.8 2.7 7.3 4.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RhoGEF PF00621.20 GAM22785.1 - 2.9e-35 122.1 3.1 2.9e-35 122.1 3.1 3.0 3 1 0 3 3 3 1 RhoGEF domain FYVE PF01363.21 GAM22785.1 - 1.5e-20 73.1 6.6 3.2e-20 72.0 6.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 GAM22785.1 - 9.8e-08 32.5 0.1 2.6e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 GAM22785.1 - 1.4e-06 28.2 0.4 1.4e-06 28.2 0.4 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain FYVE_2 PF02318.16 GAM22785.1 - 0.27 11.4 11.5 0.061 13.5 7.0 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger VWA_2 PF13519.6 GAM22786.1 - 6.7e-07 29.9 0.0 1.7e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain ubiquitin PF00240.23 GAM22786.1 - 2.7e-06 27.0 0.1 5.8e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Ras PF00071.22 GAM22786.1 - 0.0076 15.9 0.7 0.7 9.5 0.0 3.0 2 1 1 3 3 3 1 Ras family PduV-EutP PF10662.9 GAM22786.1 - 0.036 13.8 0.1 0.091 12.5 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation OKR_DC_1_N PF03709.15 GAM22786.1 - 0.081 13.2 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Pex14_N PF04695.13 GAM22786.1 - 0.5 11.0 5.6 1.6 9.4 5.6 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP1 PF08601.10 GAM22786.1 - 4.5 6.9 8.5 8.8 5.9 8.5 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 RRM_5 PF13893.6 GAM22787.1 - 2.5e-39 133.7 0.1 1.3e-24 86.2 0.2 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GAM22787.1 - 1.1e-23 82.9 0.0 1.9e-06 27.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 GAM22787.1 - 2.5e-12 46.8 0.1 1.8e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 GAM22787.1 - 3.8e-05 23.5 0.1 0.0056 16.5 0.1 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 GAM22787.1 - 0.0035 17.4 0.0 0.66 10.1 0.0 3.2 4 0 0 4 4 4 1 Limkain b1 WD40 PF00400.32 GAM22788.1 - 3.8e-33 113.0 8.4 3.5e-06 27.6 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 GAM22788.1 - 4.9e-05 22.8 0.0 0.0031 16.9 0.0 2.4 2 0 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 GAM22788.1 - 0.00012 22.3 0.3 3.8 7.9 0.0 4.1 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NOA36 PF06524.12 GAM22788.1 - 0.0019 17.6 5.7 0.0019 17.6 5.7 3.3 2 1 1 3 3 3 1 NOA36 protein Mitoc_L55 PF09776.9 GAM22788.1 - 0.11 12.2 1.9 0.37 10.5 1.9 1.9 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 SDA1 PF05285.12 GAM22788.1 - 0.42 10.0 51.9 0.46 9.8 34.7 2.1 2 0 0 2 2 2 0 SDA1 Archease PF01951.16 GAM22789.1 - 1.8e-39 135.1 2.2 2.2e-39 134.9 2.2 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Pkinase PF00069.25 GAM22790.1 - 4.3e-73 245.9 0.0 7.8e-73 245.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22790.1 - 1e-33 116.8 0.0 1.9e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM22790.1 - 2.2e-06 27.2 0.0 5.9e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like SIN1_PH PF16979.5 GAM22790.1 - 0.012 15.9 0.8 0.11 12.8 0.8 2.4 1 1 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Peptidase_C1 PF00112.23 GAM22791.1 - 4e-50 170.9 2.6 5.1e-50 170.6 2.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAM22791.1 - 0.11 11.3 0.6 0.25 10.0 0.4 1.7 1 1 1 2 2 2 0 Peptidase C1-like family WW PF00397.26 GAM22792.1 - 2.8e-11 43.3 7.6 3.2e-05 23.9 1.1 2.5 2 0 0 2 2 2 2 WW domain RPEL PF02755.15 GAM22792.1 - 5.3e-05 22.8 0.1 5.3e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 RPEL repeat START PF01852.19 GAM22793.1 - 1.3e-06 28.0 0.0 3.1e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 START domain QRPTase_C PF01729.19 GAM22794.1 - 1.9e-54 184.0 0.1 2.3e-54 183.7 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 GAM22794.1 - 3.6e-18 65.4 0.0 7e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF3449 PF11931.8 GAM22796.1 - 6.3e-64 215.2 3.4 6.3e-64 215.2 3.4 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 GAM22796.1 - 6.3e-21 74.7 5.3 1.7e-20 73.3 5.3 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 GAM22796.1 - 1.4e-09 38.0 7.5 7.6e-08 32.5 2.7 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 GAM22796.1 - 5.3e-09 35.8 0.2 1.6e-08 34.3 0.2 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 GAM22796.1 - 3.1e-08 33.7 2.3 3.1e-08 33.7 2.3 2.9 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAM22796.1 - 0.0069 16.7 7.8 0.065 13.6 0.2 3.4 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAM22796.1 - 0.0089 16.8 2.6 3.7 8.7 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger LssY_C PF14067.6 GAM22796.1 - 0.066 12.8 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 LssY C-terminus Desulfoferrod_N PF06397.12 GAM22796.1 - 0.18 11.5 0.6 0.36 10.5 0.6 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zf-C2H2_6 PF13912.6 GAM22796.1 - 4.2 7.5 8.9 0.75 9.9 2.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2076 PF09849.9 GAM22797.1 - 4.3e-06 27.0 2.0 5.1e-06 26.7 2.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF2613 PF11021.8 GAM22797.1 - 0.0023 18.0 1.1 0.0023 18.0 1.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2613) CHCH PF06747.13 GAM22797.1 - 0.0033 17.5 2.6 0.0045 17.1 2.6 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 GAM22797.1 - 0.0063 16.8 0.4 0.0095 16.2 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 FNIP PF05725.12 GAM22800.1 - 7.5e-92 301.3 32.3 1.6e-10 41.0 0.1 7.6 3 1 10 13 13 13 12 FNIP Repeat DUF5087 PF17006.5 GAM22801.1 - 7.8e-06 25.6 3.1 2.1e-05 24.3 3.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5087) FNIP PF05725.12 GAM22802.1 - 6.6e-60 199.0 11.1 1e-14 54.4 0.3 8.7 6 2 5 12 12 12 8 FNIP Repeat Glyco_hydro_16 PF00722.21 GAM22804.1 - 6e-19 68.2 0.9 6e-19 68.2 0.9 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 GAM22804.1 - 8.1e-07 27.8 0.8 8.1e-07 27.8 0.8 2.4 1 1 1 2 2 2 1 Beta-glucan synthesis-associated protein (SKN1) SOG2 PF10428.9 GAM22804.1 - 3.1 6.9 27.2 3.7 6.7 27.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RIFIN PF02009.16 GAM22804.1 - 7.2 6.4 8.8 11 5.8 8.8 1.2 1 0 0 1 1 1 0 Rifin DUF572 PF04502.13 GAM22804.1 - 7.9 6.0 12.3 11 5.5 12.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 GAM22804.1 - 9.1 3.3 13.6 12 2.8 13.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Band_7 PF01145.25 GAM22805.1 - 1.2e-12 48.2 0.0 1.2e-12 48.2 0.0 2.4 2 1 0 2 2 2 1 SPFH domain / Band 7 family DUF2407_C PF13373.6 GAM22805.1 - 0.018 15.2 0.5 0.13 12.4 0.0 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain RRM_1 PF00076.22 GAM22806.1 - 3e-08 33.4 0.0 9.6e-08 31.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 4HBT PF03061.22 GAM22806.1 - 4.2e-08 33.4 0.1 0.0039 17.5 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily Pkinase PF00069.25 GAM22807.1 - 1.3e-78 264.1 0.2 1.5e-78 263.8 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22807.1 - 7.1e-36 123.8 0.1 9.4e-36 123.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM22807.1 - 3.1e-11 43.1 0.1 7.4e-10 38.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 GAM22807.1 - 1.9e-05 24.1 0.1 2.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM22807.1 - 6.5e-05 21.9 0.1 0.00097 18.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 GAM22807.1 - 0.00042 20.0 0.5 0.00067 19.3 0.5 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAM22807.1 - 0.00058 19.9 0.0 0.03 14.2 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 GAM22807.1 - 0.0042 16.7 0.4 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 GAM22807.1 - 0.014 14.3 0.5 0.021 13.7 0.5 1.3 1 1 0 1 1 1 0 Haspin like kinase domain FNIP PF05725.12 GAM22808.1 - 4.1e-23 81.3 17.8 2.1e-13 50.2 0.6 7.2 7 0 0 7 7 7 3 FNIP Repeat LRR_4 PF12799.7 GAM22808.1 - 0.0045 17.4 7.2 3.2 8.3 0.0 6.0 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) Metallophos PF00149.28 GAM22809.1 - 1.9e-36 126.5 0.2 3.1e-36 125.8 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM22809.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RabGAP-TBC PF00566.18 GAM22810.1 - 3.8e-28 98.6 3.9 3.8e-28 98.6 3.9 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.32 GAM22812.1 - 1.5e-06 28.8 14.4 0.0013 19.5 0.4 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM22812.1 - 3.4e-06 27.3 0.6 3.4 8.0 0.0 4.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NigD_C PF17415.2 GAM22812.1 - 0.081 13.0 0.1 2.8 8.1 0.0 2.5 1 1 1 2 2 2 0 NigD-like C-terminal beta sandwich domain Dicty_REP PF05086.12 GAM22812.1 - 0.13 10.2 11.2 0.23 9.4 11.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Retinal PF15449.6 GAM22812.1 - 0.63 7.7 15.2 0.85 7.3 15.2 1.1 1 0 0 1 1 1 0 Retinal protein MAP65_ASE1 PF03999.12 GAM22812.1 - 1.3 7.6 9.8 1.8 7.2 9.8 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Nucleo_P87 PF07267.11 GAM22812.1 - 2 7.2 7.2 2.6 6.8 7.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box-like PF12937.7 GAM22813.1 - 1.1e-06 28.4 0.5 3.8e-06 26.7 0.5 2.0 1 0 0 1 1 1 1 F-box-like Cullin PF00888.22 GAM22813.1 - 1.6e-05 23.8 7.6 2e-05 23.4 3.0 2.7 1 1 1 2 2 2 1 Cullin family F-box PF00646.33 GAM22813.1 - 0.072 13.0 0.4 0.25 11.3 0.4 1.9 1 0 0 1 1 1 0 F-box domain PIP5K PF01504.18 GAM22814.1 - 7.4e-79 264.8 0.6 7.4e-79 264.8 0.6 3.6 4 0 0 4 4 4 1 Phosphatidylinositol-4-phosphate 5-Kinase Ank_4 PF13637.6 GAM22814.1 - 4.8e-30 103.6 1.2 7e-12 45.6 0.0 5.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM22814.1 - 5e-25 87.9 0.7 3.8e-11 43.4 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM22814.1 - 1.6e-24 85.6 2.5 2.1e-08 34.2 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM22814.1 - 1.5e-20 72.7 1.2 0.0028 18.0 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 GAM22814.1 - 2.5e-17 61.2 0.4 0.0011 19.3 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat EF-hand_7 PF13499.6 GAM22814.1 - 6.1e-14 52.2 1.1 4.7e-06 27.0 0.7 3.6 3 0 0 3 3 3 2 EF-hand domain pair C1_1 PF00130.22 GAM22814.1 - 2.1e-12 46.7 5.8 3.6e-12 46.0 5.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_1 PF00036.32 GAM22814.1 - 2.7e-10 39.0 3.8 0.0034 16.8 0.8 3.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GAM22814.1 - 2.7e-10 39.3 5.1 0.0046 16.8 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 GAM22814.1 - 3.2e-05 23.7 4.9 0.12 12.2 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair NADPH_Ox PF08414.10 GAM22814.1 - 0.0033 17.7 1.0 0.012 15.9 0.1 2.5 2 0 0 2 2 2 1 Respiratory burst NADPH oxidase EF-hand_5 PF13202.6 GAM22814.1 - 0.042 13.4 7.3 0.26 10.9 1.2 3.5 4 0 0 4 4 4 0 EF hand C1_2 PF03107.16 GAM22814.1 - 0.054 13.8 3.2 0.12 12.7 3.2 1.6 1 0 0 1 1 1 0 C1 domain AIG1 PF04548.16 GAM22814.1 - 4 6.7 9.1 0.31 10.4 0.3 2.3 2 0 0 2 2 2 0 AIG1 family Trypan_PARP PF05887.11 GAM22814.1 - 4.3 7.3 6.4 0.42 10.6 1.4 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SPARC_Ca_bdg PF10591.9 GAM22814.1 - 9.7 6.5 15.8 0.5 10.7 0.1 4.1 4 0 0 4 4 3 0 Secreted protein acidic and rich in cysteine Ca binding region FAD_binding_3 PF01494.19 GAM22815.1 - 7.7e-24 84.6 0.0 1.8e-23 83.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAM22815.1 - 7.3e-05 22.9 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAM22815.1 - 0.00025 20.4 0.2 0.003 16.8 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM22815.1 - 0.00027 20.7 0.0 0.67 9.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 GAM22815.1 - 0.0032 16.6 0.0 0.063 12.3 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase GIDA PF01134.22 GAM22815.1 - 0.011 14.9 0.2 0.02 14.0 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAM22815.1 - 0.041 13.1 0.1 7.6 5.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HORMA PF02301.18 GAM22816.1 - 2.2e-24 86.3 0.1 4.9e-24 85.1 0.1 1.5 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 GAM22816.1 - 0.00052 19.9 0.7 0.0018 18.2 0.5 2.0 1 1 1 2 2 2 1 Bacterial HORMA domain 2 ATG101 PF07855.12 GAM22816.1 - 0.022 14.8 0.0 0.26 11.3 0.0 2.0 1 1 0 1 1 1 0 Autophagy-related protein 101 DUF2791 PF10923.8 GAM22816.1 - 0.1 11.5 0.1 0.17 10.7 0.1 1.4 1 1 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) IMPa_N_2 PF18650.1 GAM22816.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain zf-CHY PF05495.12 GAM22817.1 - 7.2e-20 71.3 24.8 7.2e-20 71.3 24.8 3.7 2 1 1 3 3 3 1 CHY zinc finger zinc_ribbon_6 PF14599.6 GAM22817.1 - 6.1e-19 67.8 1.2 6.1e-19 67.8 1.2 4.5 2 1 2 4 4 4 1 Zinc-ribbon zf-RING_2 PF13639.6 GAM22817.1 - 8.8e-09 35.6 5.1 8.8e-09 35.6 5.1 5.4 3 2 3 6 6 6 1 Ring finger domain zf-C3HC4 PF00097.25 GAM22817.1 - 2e-07 30.8 5.8 2e-07 30.8 5.8 5.2 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM22817.1 - 5.9e-07 29.4 2.0 5.9e-07 29.4 2.0 4.2 4 2 1 5 5 5 1 RING-type zinc-finger zf-RING_4 PF14570.6 GAM22817.1 - 9.3e-05 22.1 3.5 9.3e-05 22.1 3.5 4.8 2 2 1 3 3 3 1 RING/Ubox like zinc-binding domain TFIIA PF03153.13 GAM22817.1 - 0.1 12.6 4.4 0.12 12.3 4.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mito_carr PF00153.27 GAM22818.1 - 6.6e-73 240.7 4.5 6.4e-24 83.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein EGF_MSP1_1 PF12946.7 GAM22818.1 - 0.25 11.4 0.3 3.2 7.9 0.1 2.4 2 0 0 2 2 2 0 MSP1 EGF domain 1 Mob1_phocein PF03637.17 GAM22819.1 - 3.3e-74 248.5 0.0 4e-74 248.3 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family SF1-HH PF16275.5 GAM22820.1 - 3.8e-35 120.6 0.2 3.8e-35 120.6 0.2 2.6 3 1 0 3 3 3 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 GAM22820.1 - 2.9e-10 39.8 0.1 6.5e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 KH domain CBM49 PF09478.10 GAM22821.1 - 3.2e-17 62.6 0.1 4.6e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 UPF0164 PF03687.13 GAM22821.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) VPS9 PF02204.18 GAM22822.1 - 5.6e-25 87.6 0.1 1.7e-24 86.0 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH PF00169.29 GAM22822.1 - 0.016 15.7 0.0 0.049 14.1 0.0 1.9 1 0 0 1 1 1 0 PH domain Pkinase PF00069.25 GAM22823.1 - 3.5e-66 223.3 0.0 4.7e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22823.1 - 4.2e-46 157.3 0.0 6.5e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAM22823.1 - 1.4e-15 57.3 0.0 1.4e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 GAM22823.1 - 0.00011 21.2 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAM22823.1 - 0.0058 16.0 0.0 0.013 14.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAM22823.1 - 0.13 11.2 0.0 0.67 8.8 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain PH PF00169.29 GAM22824.1 - 2.1e-11 44.2 0.1 9.2e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 PH domain DUF4139 PF13598.6 GAM22824.1 - 1.6e-07 31.3 0.0 0.019 14.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4139) SAM_1 PF00536.30 GAM22824.1 - 4.6e-07 30.2 0.0 9.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM22824.1 - 9.6e-06 25.6 0.0 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 GAM22824.1 - 4.9e-05 23.7 0.7 0.0007 20.0 0.7 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 GAM22824.1 - 0.065 13.6 0.0 0.21 12.0 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain ATP-synt_ab PF00006.25 GAM22825.1 - 4.1e-68 229.2 0.0 6.1e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAM22825.1 - 7.8e-11 42.3 0.4 1.4e-10 41.5 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Rad10 PF03834.14 GAM22825.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Ribosomal_L18A PF01775.17 GAM22826.1 - 2.7e-49 166.3 3.0 3.5e-49 165.9 3.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Acetyltransf_9 PF13527.7 GAM22827.1 - 1.6e-06 28.2 0.0 3.1e-05 24.1 0.0 2.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM22827.1 - 0.045 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CN_hydrolase PF00795.22 GAM22828.1 - 1.6e-39 135.9 0.0 2.2e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 GAM22828.1 - 4e-26 91.6 0.0 1.3e-25 89.9 0.0 1.8 2 0 0 2 2 2 1 NAD synthase GHL6 PF14871.6 GAM22829.1 - 5.1e-11 42.9 0.0 9.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 zf-CCHC PF00098.23 GAM22829.1 - 1.4e-08 34.4 8.5 0.00079 19.4 0.8 2.7 2 0 0 2 2 2 2 Zinc knuckle Glyco_hydro_42M PF08532.10 GAM22829.1 - 0.00018 21.1 0.0 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain zf-CCHC_4 PF14392.6 GAM22829.1 - 0.0016 18.2 5.5 0.055 13.2 1.3 2.6 2 0 0 2 2 2 2 Zinc knuckle DUF4015 PF13200.6 GAM22829.1 - 0.002 17.3 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative glycosyl hydrolase domain zf-CCHC_2 PF13696.6 GAM22829.1 - 0.017 15.0 2.0 0.017 15.0 2.0 2.3 2 0 0 2 2 2 0 Zinc knuckle Anti-TRAP PF15777.5 GAM22829.1 - 0.21 11.6 1.6 0.92 9.5 0.3 2.7 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-C2H2_10 PF16588.5 GAM22829.1 - 9.3 6.1 7.6 1 9.2 2.2 2.0 2 0 0 2 2 2 0 C2H2 zinc-finger Ras PF00071.22 GAM22830.1 - 2.2e-59 199.7 0.0 2.6e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM22830.1 - 1.3e-19 70.6 0.0 1.8e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM22830.1 - 2.6e-10 40.0 0.0 2.8e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM22830.1 - 8e-07 28.8 0.2 2.2e-06 27.3 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM22830.1 - 0.00094 19.1 0.0 1.7 8.5 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM22830.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase TPP_enzyme_M PF00205.22 GAM22830.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Gtr1_RagA PF04670.12 GAM22830.1 - 0.15 11.4 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region EF-hand_7 PF13499.6 GAM22832.1 - 3.6e-12 46.6 0.0 1.2e-10 41.7 0.0 3.2 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_13 PF17958.1 GAM22832.1 - 9e-12 44.6 0.0 2e-09 37.1 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 GAM22832.1 - 9.3e-06 24.8 3.1 0.013 15.0 0.1 3.6 4 0 0 4 4 3 2 EF hand Apt1 PF10351.9 GAM22832.1 - 0.00012 21.1 10.5 0.00018 20.5 10.5 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain EF-hand_6 PF13405.6 GAM22832.1 - 0.0002 21.0 0.6 0.87 9.7 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain Macoilin PF09726.9 GAM22832.1 - 0.00021 20.1 9.2 0.00028 19.6 9.2 1.2 1 0 0 1 1 1 1 Macoilin family Presenilin PF01080.17 GAM22832.1 - 0.00054 18.8 3.3 0.0008 18.3 3.3 1.2 1 0 0 1 1 1 1 Presenilin EF-hand_5 PF13202.6 GAM22832.1 - 0.0032 16.9 0.5 0.22 11.1 0.0 2.7 2 0 0 2 2 2 1 EF hand CDC45 PF02724.14 GAM22832.1 - 0.012 13.9 7.8 0.018 13.4 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 GAM22832.1 - 0.035 13.9 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Connexin PI3K_1B_p101 PF10486.9 GAM22832.1 - 0.052 11.3 9.2 0.082 10.7 9.2 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit EF-hand_8 PF13833.6 GAM22832.1 - 0.072 12.9 2.7 0.56 10.1 0.1 3.1 3 0 0 3 3 2 0 EF-hand domain pair DUF2207 PF09972.9 GAM22832.1 - 0.084 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Neur_chan_memb PF02932.16 GAM22832.1 - 0.15 12.1 3.9 0.25 11.4 3.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NAM-associated PF14303.6 GAM22832.1 - 0.29 11.8 16.3 0.54 11.0 16.3 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RR_TM4-6 PF06459.12 GAM22832.1 - 1.4 8.7 11.4 2.3 8.0 11.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 GAM22832.1 - 1.5 8.0 7.8 2.3 7.3 7.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Smg8_Smg9 PF10220.9 GAM22832.1 - 4.8 5.4 12.5 6.9 4.8 12.5 1.1 1 0 0 1 1 1 0 Smg8_Smg9 SprA-related PF12118.8 GAM22832.1 - 5 6.2 18.8 7.6 5.6 18.8 1.1 1 0 0 1 1 1 0 SprA-related family DUF5427 PF10310.9 GAM22832.1 - 5.1 5.9 17.2 7.8 5.3 17.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Dsh_C PF12316.8 GAM22832.1 - 7.3 6.9 26.5 14 6.0 26.5 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Raftlin PF15250.6 GAM22832.1 - 8.7 5.0 11.0 18 3.9 11.0 1.5 1 0 0 1 1 1 0 Raftlin DSPc PF00782.20 GAM22833.1 - 5.8e-34 116.8 1.8 9.7e-34 116.0 1.8 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAM22833.1 - 4.7e-06 26.8 0.1 1.2e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Rhodanese PF00581.20 GAM22833.1 - 9.9e-06 26.0 0.1 0.0093 16.5 0.0 2.6 3 0 0 3 3 3 2 Rhodanese-like domain Y_phosphatase PF00102.27 GAM22833.1 - 4.8e-05 23.0 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 GAM22833.1 - 0.035 13.8 0.1 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 GAM22833.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 GAM22833.1 - 0.13 12.2 0.1 0.78 9.7 0.1 2.1 2 1 0 2 2 2 0 Tyrosine phosphatase family SKA1 PF07160.12 GAM22834.1 - 0.0011 18.9 1.2 0.0011 18.9 1.2 2.7 2 1 1 3 3 3 1 Spindle and kinetochore-associated protein 1 Dor1 PF04124.12 GAM22834.1 - 0.0018 17.0 1.7 0.002 16.9 0.4 1.6 2 0 0 2 2 2 1 Dor1-like family Phage_lysis PF03245.13 GAM22834.1 - 0.1 12.7 0.7 0.23 11.6 0.7 1.6 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein FlxA PF14282.6 GAM22834.1 - 0.31 11.0 7.8 0.11 12.4 1.9 3.1 2 1 1 3 3 3 0 FlxA-like protein MscS_porin PF12795.7 GAM22834.1 - 0.33 10.5 3.6 0.7 9.4 3.6 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Hyccin PF09790.9 GAM22835.1 - 3.9e-41 141.2 5.9 1.4e-40 139.4 5.9 1.8 1 1 0 1 1 1 1 Hyccin RasGAP PF00616.19 GAM22836.1 - 1.1e-33 116.8 2.4 1.9e-22 80.0 0.0 3.7 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase BAR_3 PF16746.5 GAM22836.1 - 5.6e-11 42.6 13.0 5.6e-11 42.6 13.0 2.5 3 1 0 3 3 3 1 BAR domain of APPL family BAR PF03114.18 GAM22836.1 - 0.00052 19.7 5.8 0.00052 19.7 5.8 3.0 2 1 1 3 3 3 1 BAR domain HMG-CoA_red PF00368.18 GAM22836.1 - 0.058 12.4 2.3 0.1 11.6 2.3 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase Spore_coat_CotO PF14153.6 GAM22836.1 - 0.71 9.8 10.4 0.11 12.4 2.2 2.4 2 0 0 2 2 2 0 Spore coat protein CotO TFIIA PF03153.13 GAM22836.1 - 4.2 7.3 14.4 7.5 6.4 4.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ABC_tran_Xtn PF12848.7 GAM22836.1 - 6.5 6.9 17.9 0.34 11.0 9.9 2.6 2 0 0 2 2 2 0 ABC transporter HisKA PF00512.25 GAM22836.1 - 9 6.4 6.7 16 5.6 0.6 3.6 3 1 1 4 4 4 0 His Kinase A (phospho-acceptor) domain PPR_2 PF13041.6 GAM22837.1 - 1.7e-37 127.3 13.3 1.4e-08 34.8 0.1 8.1 4 3 4 8 8 8 7 PPR repeat family PPR_3 PF13812.6 GAM22837.1 - 3.2e-27 94.4 9.9 6.8e-08 32.5 0.1 5.9 4 2 2 6 6 6 6 Pentatricopeptide repeat domain PPR PF01535.20 GAM22837.1 - 1.2e-23 81.6 6.7 3.5e-08 33.1 0.2 6.7 6 0 0 6 6 6 5 PPR repeat PPR_long PF17177.4 GAM22837.1 - 1e-19 70.8 0.2 4.3e-10 39.3 0.0 3.4 2 2 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAM22837.1 - 4.4e-16 58.3 4.1 0.00074 19.2 0.0 6.8 7 0 0 7 7 7 4 PPR repeat TPR_19 PF14559.6 GAM22837.1 - 0.00045 20.7 0.0 5 7.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 GAM22837.1 - 0.014 15.1 0.0 0.95 9.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Exog_C PF18026.1 GAM22837.1 - 0.056 13.5 4.5 4 7.6 0.0 4.6 4 1 1 5 5 5 0 Endo/exonuclease (EXOG) C-terminal domain BTAD PF03704.17 GAM22837.1 - 0.13 12.7 0.0 1.8 9.0 0.1 2.4 2 0 0 2 2 2 0 Bacterial transcriptional activator domain DUF1955 PF09205.10 GAM22837.1 - 0.13 11.9 5.7 0.14 11.9 0.0 3.1 4 1 0 4 4 4 0 Domain of unknown function (DUF1955) Hemocyanin_N PF03722.14 GAM22837.1 - 0.56 10.7 6.4 0.4 11.2 1.0 3.1 1 1 3 4 4 4 0 Hemocyanin, all-alpha domain Aldedh PF00171.22 GAM22838.1 - 1.1e-119 400.0 0.0 1.4e-119 399.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAM22838.1 - 6.2e-05 22.2 0.0 9.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Not1 PF04054.15 GAM22840.1 - 3.9e-146 486.7 4.4 3.9e-146 486.7 4.4 3.3 4 0 0 4 4 4 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 GAM22840.1 - 6.7e-80 267.7 4.0 4.4e-79 265.0 4.0 2.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 GAM22840.1 - 1.1e-57 194.3 0.7 1.1e-57 194.3 0.7 2.9 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 GAM22840.1 - 3.1e-54 182.9 0.3 1.5e-53 180.7 0.3 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 GAM22840.1 - 3.3e-29 101.9 3.6 3.3e-29 101.9 3.6 3.2 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat ADH_zinc_N PF00107.26 GAM22841.1 - 1.4e-22 80.1 0.0 2.6e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM22841.1 - 3.5e-11 42.9 0.0 9.5e-11 41.6 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM22841.1 - 9.2e-10 39.7 0.0 3e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAM22841.1 - 5.3e-05 22.6 0.4 9.1e-05 21.8 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 GAM22841.1 - 0.0017 17.8 0.5 0.0025 17.3 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme adh_short PF00106.25 GAM22841.1 - 0.017 14.6 0.4 0.029 13.8 0.4 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF2855 PF11017.8 GAM22841.1 - 0.15 11.8 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Rad52_Rad22 PF04098.15 GAM22842.1 - 9.5e-28 97.0 0.0 1.5e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Serglycin PF04360.12 GAM22842.1 - 0.064 13.2 5.5 0.11 12.4 5.5 1.4 1 0 0 1 1 1 0 Serglycin CdiA_C_tRNase PF18664.1 GAM22842.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain Metallophos PF00149.28 GAM22843.1 - 4e-15 56.9 0.7 7.5e-15 56.0 0.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM22843.1 - 5.3e-09 36.5 1.2 1.1e-08 35.4 1.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 GAM22843.1 - 0.0027 17.1 0.2 0.0057 16.0 0.1 1.5 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily NIF3 PF01784.18 GAM22843.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) DUF2340 PF10209.9 GAM22844.1 - 1.5e-42 144.8 1.2 1.9e-42 144.5 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DENN PF02141.21 GAM22845.1 - 4.9e-50 170.1 3.3 4.9e-50 170.1 3.3 2.2 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 GAM22845.1 - 9.9e-12 45.4 0.5 5.2e-11 43.1 0.5 2.4 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 GAM22845.1 - 1.1e-07 31.7 1.5 1.1e-07 31.7 1.5 2.3 2 0 0 2 2 2 1 dDENN domain SPA PF08616.10 GAM22845.1 - 0.0095 15.9 3.4 0.012 15.5 0.3 2.7 3 0 0 3 3 3 1 Stabilization of polarity axis Avl9 PF09794.9 GAM22845.1 - 1.2 7.7 6.0 0.084 11.6 0.1 2.1 3 0 0 3 3 3 0 Transport protein Avl9 CSTF_C PF14304.6 GAM22845.1 - 1.6 8.4 3.8 12 5.6 0.1 2.8 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal CBS PF00571.28 GAM22846.1 - 4.7e-33 113.4 1.9 1.5e-11 44.5 0.1 4.2 4 0 0 4 4 4 4 CBS domain Recep_L_domain PF01030.24 GAM22846.1 - 0.097 12.8 1.1 0.16 12.1 0.2 1.8 2 0 0 2 2 2 0 Receptor L domain IFRD PF05004.13 GAM22847.1 - 5.3e-17 61.9 12.8 1.9e-15 56.8 12.8 2.1 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) SDA1 PF05285.12 GAM22847.1 - 0.0073 15.8 10.6 0.009 15.5 10.6 1.2 1 0 0 1 1 1 1 SDA1 TetR_C_6 PF13977.6 GAM22847.1 - 0.042 14.1 0.5 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal PPP4R2 PF09184.11 GAM22847.1 - 0.074 12.6 8.4 0.14 11.7 8.4 1.5 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 GAM22847.1 - 0.62 8.1 19.4 1.2 7.1 19.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GAM22847.1 - 0.64 8.2 17.9 0.94 7.6 17.9 1.2 1 0 0 1 1 1 0 Nop14-like family Tub_N PF16322.5 GAM22847.1 - 1 9.7 10.4 2 8.8 10.4 1.5 1 0 0 1 1 1 0 Tubby N-terminal Zip PF02535.22 GAM22847.1 - 1.1 8.4 3.0 1.6 7.9 3.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ThrE PF06738.12 GAM22848.1 - 5.9e-60 202.6 28.1 2.3e-52 177.8 4.3 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAM22848.1 - 4.4e-09 36.6 35.3 9.7e-07 29.0 14.1 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE TruB_C_2 PF16198.5 GAM22848.1 - 0.099 12.8 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain Myb_DNA-binding PF00249.31 GAM22849.1 - 7.9e-06 26.0 0.1 1.6e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3915 PF13054.6 GAM22849.1 - 2.3 8.2 34.4 8.1 6.5 16.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) Sel1 PF08238.12 GAM22850.1 - 9.5e-45 150.0 45.8 5.7e-07 30.0 0.2 11.7 13 0 0 13 13 13 10 Sel1 repeat TMEM51 PF15345.6 GAM22850.1 - 0.068 13.0 0.1 0.068 13.0 0.1 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 Antimicrobial17 PF08129.11 GAM22850.1 - 0.079 13.0 0.2 0.31 11.1 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta enterocin family TPR_19 PF14559.6 GAM22850.1 - 3.9 8.1 14.7 14 6.3 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat B-block_TFIIIC PF04182.12 GAM22852.1 - 2.4e-12 46.8 6.7 7.7e-11 42.0 0.8 4.7 5 0 0 5 5 5 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 GAM22852.1 - 0.00014 21.3 3.9 18 5.0 0.0 6.5 7 0 0 7 7 7 3 Winged helix-turn-helix DNA-binding DNA_pol_A_exo1 PF01612.20 GAM22853.1 - 0.0022 17.7 0.1 0.0036 17.0 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease CAP PF00188.26 GAM22854.1 - 0.86 10.5 5.1 0.17 12.7 0.7 2.0 1 1 1 2 2 2 0 Cysteine-rich secretory protein family NUDIX PF00293.28 GAM22855.1 - 1.5e-12 47.7 0.0 2.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.12 GAM22855.1 - 1.1 9.6 4.5 7.4 7.0 0.3 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Pep1_7 PF17232.2 GAM22856.1 - 2.8 8.5 8.0 0.18 12.3 1.5 2.2 2 1 0 2 2 2 0 Elicitor peptide 1-7 Vps5 PF09325.10 GAM22857.1 - 1e-54 185.6 5.1 1e-54 185.6 5.1 1.6 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 GAM22857.1 - 5.1e-24 84.4 0.3 1.9e-23 82.6 0.1 2.1 2 0 0 2 2 2 1 PX domain Apolipoprotein PF01442.18 GAM22857.1 - 0.0099 15.8 2.3 0.02 14.8 2.3 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain SbsC_C PF18058.1 GAM22857.1 - 0.028 14.7 1.4 0.079 13.2 1.4 1.8 1 0 0 1 1 1 0 SbsC C-terminal domain ACCA PF03255.14 GAM22857.1 - 0.16 11.8 2.5 0.22 11.4 1.3 1.8 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Uds1 PF15456.6 GAM22857.1 - 0.17 12.0 4.0 0.68 10.1 4.0 2.0 1 1 0 1 1 1 0 Up-regulated During Septation BAR PF03114.18 GAM22857.1 - 0.25 11.0 12.6 0.012 15.3 6.3 2.1 3 1 0 3 3 3 0 BAR domain MinC_N PF05209.13 GAM22858.1 - 4.1e-05 23.5 0.1 5.2e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain MinC_C PF03775.16 GAM22859.1 - 4.7e-29 100.4 0.1 6.9e-29 99.8 0.1 1.3 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain FapA PF03961.13 GAM22859.1 - 0.0041 15.8 0.4 0.0052 15.5 0.4 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A GyrI-like PF06445.15 GAM22860.1 - 2.4e-30 105.9 0.1 2.7e-30 105.7 0.1 1.0 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 GAM22860.1 - 6.8e-10 39.3 0.0 8.2e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Integron-associated effector binding protein Solute_trans_a PF03619.16 GAM22861.1 - 1.1e-37 130.0 8.8 1.5e-37 129.6 8.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Radical_SAM_C PF16199.5 GAM22862.1 - 4e-32 110.1 0.0 7.7e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 GAM22862.1 - 2.2e-19 70.4 0.0 9.7e-19 68.3 0.0 2.1 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 GAM22862.1 - 1.3e-12 48.0 0.1 2.3e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM22862.1 - 2e-06 27.7 0.1 5.1e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM22862.1 - 0.00062 20.2 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM22862.1 - 0.025 14.5 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein TPT PF03151.16 GAM22863.1 - 5.9e-30 104.6 28.9 7e-30 104.4 28.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAM22863.1 - 2.9e-09 37.2 44.1 4.8e-06 26.8 16.6 2.5 2 1 0 2 2 2 2 EamA-like transporter family DUF2681 PF10883.8 GAM22863.1 - 0.031 14.7 4.0 0.031 14.7 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) 7TMR-DISM_7TM PF07695.11 GAM22863.1 - 0.71 9.7 49.7 0.23 11.3 15.1 2.6 1 1 2 3 3 3 0 7TM diverse intracellular signalling DUF4834 PF16118.5 GAM22863.1 - 2 9.5 4.7 0.51 11.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Fra10Ac1 PF09725.9 GAM22864.1 - 3.3e-35 120.9 2.7 8.8e-35 119.5 2.7 1.7 1 1 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 PBP1_TM PF14812.6 GAM22864.1 - 6.7 7.2 21.6 1.6 9.1 8.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNARE_assoc PF09335.11 GAM22865.1 - 0.00015 22.2 1.6 0.00015 22.2 1.6 2.8 4 1 0 4 4 4 1 SNARE associated Golgi protein TFIID-18kDa PF02269.16 GAM22865.1 - 0.15 12.1 0.3 0.33 11.0 0.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TUG-UBL1 PF11470.8 GAM22866.1 - 0.00034 20.8 0.1 0.0037 17.4 0.0 2.6 2 0 0 2 2 2 1 TUG ubiquitin-like domain RA PF00788.23 GAM22866.1 - 0.0025 18.4 0.0 0.019 15.6 0.0 2.5 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain FERM_N PF09379.10 GAM22866.1 - 0.0036 17.2 0.1 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 FERM N-terminal domain Tn7_Tnp_TnsA_C PF08721.11 GAM22866.1 - 6.2 7.5 28.7 0.22 12.2 1.9 6.3 3 1 3 6 6 6 0 TnsA endonuclease C terminal SseB PF07179.12 GAM22866.1 - 8.5 6.7 10.7 0.65 10.3 1.7 2.8 2 0 0 2 2 2 0 SseB protein N-terminal domain RhoGEF PF00621.20 GAM22867.1 - 1.2e-37 130.0 7.7 2e-37 129.2 7.7 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAM22867.1 - 0.00023 21.6 0.1 0.00089 19.7 0.1 2.0 1 0 0 1 1 1 1 PH domain NAD_binding_4 PF07993.12 GAM22868.1 - 1.9e-53 181.3 0.0 3.4e-53 180.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAM22868.1 - 1.8e-34 119.1 0.0 2.6e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAM22868.1 - 1.7e-09 37.5 0.0 3.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAM22868.1 - 5.3e-06 26.7 0.1 1.8e-05 25.0 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 GAM22868.1 - 2.6e-05 23.4 0.3 7e-05 22.0 0.3 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM22868.1 - 0.0084 15.5 0.1 0.091 12.1 0.1 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM22868.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAM22868.1 - 0.013 14.6 0.1 0.99 8.4 0.0 2.8 2 1 0 2 2 2 0 RmlD substrate binding domain DDE_2 PF02914.15 GAM22868.1 - 0.045 13.5 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage Mu transposase NAD_binding_4 PF07993.12 GAM22869.1 - 1.2e-53 181.9 0.0 1.7e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAM22869.1 - 1.1e-43 149.4 0.0 4e-43 147.6 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAM22869.1 - 1.6e-09 37.6 0.0 3.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM22869.1 - 2.6e-07 29.9 0.0 8.6e-07 28.2 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 GAM22869.1 - 0.00027 21.2 0.1 0.00067 20.0 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 GAM22869.1 - 0.00033 20.2 0.0 0.0012 18.3 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM22869.1 - 0.00047 19.3 0.1 0.052 12.6 0.0 3.0 2 1 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAM22869.1 - 0.095 11.8 0.0 0.23 10.6 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAM22869.1 - 0.11 12.4 0.1 8.1 6.3 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H-binding AMP-binding_C PF13193.6 GAM22869.1 - 0.13 13.3 0.0 0.49 11.4 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain FNIP PF05725.12 GAM22870.1 - 1.7e-79 261.8 21.7 6e-10 39.1 0.0 9.3 6 2 0 9 9 9 8 FNIP Repeat CTK3 PF12243.8 GAM22873.1 - 1.1e-11 44.8 0.5 2.4e-11 43.7 0.5 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 GAM22873.1 - 4.3e-11 43.5 0.1 1.6e-10 41.7 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CpXC PF14353.6 GAM22873.1 - 2.8 8.0 5.9 0.24 11.5 0.1 2.2 2 2 0 2 2 2 0 CpXC protein LINES_N PF14694.6 GAM22874.1 - 2.1e-12 47.2 2.0 4.5e-12 46.1 2.0 1.5 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 GAM22874.1 - 2.4e-08 33.3 1.9 2.1e-05 23.9 0.3 2.9 2 0 0 2 2 2 2 Lines C-terminus FUSC_2 PF13515.6 GAM22875.1 - 0.00046 20.3 11.7 0.00062 19.9 10.9 1.6 1 1 0 1 1 1 1 Fusaric acid resistance protein-like DUF3021 PF11457.8 GAM22875.1 - 0.11 12.8 19.9 0.33 11.3 19.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) FUSC_2 PF13515.6 GAM22876.1 - 2e-12 47.3 13.9 2.7e-12 46.9 13.2 1.5 1 1 0 1 1 1 1 Fusaric acid resistance protein-like ALMT PF11744.8 GAM22876.1 - 6.9e-10 38.4 6.4 1.1e-09 37.7 6.4 1.3 1 0 0 1 1 1 1 Aluminium activated malate transporter FUSC PF04632.12 GAM22876.1 - 0.0001 21.0 0.0 0.00015 20.5 0.0 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein family ORC2 PF04084.14 GAM22877.1 - 2e-87 293.2 0.4 2.6e-87 292.9 0.4 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 RhoGAP PF00620.27 GAM22878.1 - 7e-13 48.7 0.1 1.7e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain DHHW PF14286.6 GAM22878.1 - 0.98 8.7 0.0 0.98 8.7 0.0 2.4 2 0 0 2 2 2 0 DHHW protein DUF948 PF06103.11 GAM22878.1 - 1 9.7 3.1 10 6.5 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SOG2 PF10428.9 GAM22878.1 - 2.8 7.1 38.5 4.4 6.4 38.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_M73 PF12389.8 GAM22879.1 - 0.018 14.9 1.8 0.022 14.6 0.1 1.9 2 0 0 2 2 2 0 Camelysin metallo-endopeptidase TGS PF02824.21 GAM22879.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 TGS domain BSP_II PF05432.11 GAM22879.1 - 0.3 10.7 5.2 0.53 9.9 5.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DNA_pol_B_3 PF08408.10 GAM22879.1 - 0.52 10.5 3.6 0.59 10.3 0.7 2.3 2 0 0 2 2 2 0 DNA polymerase family B viral insert DUF3484 PF11983.8 GAM22879.1 - 1.6 9.9 7.3 0.54 11.4 0.5 2.8 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch DUF3720 PF12517.8 GAM22879.1 - 3.4 8.7 11.1 3.8 8.5 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) ECH_2 PF16113.5 GAM22880.1 - 1.6e-119 399.3 0.0 1.9e-119 399.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAM22880.1 - 1.2e-24 87.0 0.0 8e-24 84.3 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase TPT PF03151.16 GAM22881.1 - 7.9e-14 51.7 28.0 4.3e-11 42.7 18.5 2.1 1 1 1 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 GAM22881.1 - 0.026 14.7 29.3 0.29 11.3 10.9 2.9 2 1 0 2 2 2 0 EamA-like transporter family Lipoprotein_17 PF04200.12 GAM22881.1 - 0.13 12.6 2.4 0.29 11.5 2.4 1.6 1 0 0 1 1 1 0 Lipoprotein associated domain Band_3_cyto PF07565.13 GAM22881.1 - 0.27 11.0 4.0 0.47 10.2 4.0 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MCM_bind PF09739.9 GAM22881.1 - 0.4 9.1 7.0 0.54 8.6 7.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor UDPGP PF01704.18 GAM22882.1 - 2.9e-185 615.8 0.3 3.6e-185 615.5 0.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NST1 PF13945.6 GAM22883.1 - 1.1e-45 156.1 18.0 1.1e-45 156.1 18.0 7.0 5 2 2 7 7 7 1 Salt tolerance down-regulator Polysacc_deac_1 PF01522.21 GAM22883.1 - 3.4 7.6 9.4 0.66 9.9 4.4 2.5 2 0 0 2 2 2 0 Polysaccharide deacetylase tRNA-synt_2 PF00152.20 GAM22884.1 - 1.1e-92 310.5 0.2 1.3e-92 310.3 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAM22884.1 - 1.6e-09 37.6 0.6 3.8e-09 36.4 0.1 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAM22884.1 - 0.05 13.1 0.0 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Neuropeptide_S PF14993.6 GAM22885.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 Neuropeptide S precursor protein YpsA PF06908.11 GAM22886.1 - 0.041 13.9 1.7 0.079 12.9 1.7 1.6 1 1 0 1 1 1 0 YspA SLOG family DUF4692 PF15763.5 GAM22886.1 - 0.8 10.2 5.4 1.5 9.3 5.1 1.5 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Pkinase PF00069.25 GAM22887.1 - 2.2e-73 246.9 0.0 2.9e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22887.1 - 6.9e-35 120.6 0.0 9.5e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 GAM22887.1 - 2.3e-22 79.5 0.5 5.3e-22 78.3 0.5 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM22887.1 - 1.2e-07 32.1 3.5 4.8e-06 26.9 3.5 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAM22887.1 - 3.4e-07 30.5 0.2 7.3e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase_C PF00433.24 GAM22887.1 - 0.00043 20.9 1.2 0.00085 20.0 1.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_6 PF15406.6 GAM22887.1 - 0.0048 17.2 0.0 0.0087 16.3 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Haspin_kinase PF12330.8 GAM22887.1 - 0.0086 15.1 0.8 0.011 14.6 0.8 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM22887.1 - 0.014 15.3 0.0 0.03 14.3 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 GAM22887.1 - 0.018 14.7 0.1 3.1 7.4 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PH_9 PF15410.6 GAM22887.1 - 0.03 14.7 0.7 0.36 11.2 0.1 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain Kinase-like PF14531.6 GAM22887.1 - 0.034 13.5 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 GAM22887.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phosphorylase PF00343.20 GAM22888.1 - 0 1047.2 1.1 0 1047.0 1.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase PCI PF01399.27 GAM22889.1 - 2.4e-22 79.4 2.2 9.7e-22 77.5 0.1 2.7 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 GAM22889.1 - 9.8e-15 54.4 0.7 2.4e-14 53.1 0.7 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain VHL_C PF17211.3 GAM22889.1 - 0.06 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 VHL box domain ERp29 PF07749.12 GAM22889.1 - 8.1 7.4 8.8 0.53 11.2 0.3 3.3 3 1 1 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain G-alpha PF00503.20 GAM22890.1 - 1e-95 320.9 3.1 1.3e-95 320.6 3.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM22890.1 - 7.1e-14 51.6 0.1 9.4e-10 38.2 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAM22890.1 - 0.00013 22.2 0.8 0.53 10.5 0.0 3.0 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAM22890.1 - 0.00044 19.7 0.3 0.11 11.9 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM22890.1 - 0.00086 19.4 0.2 2.7 8.1 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase HTH_51 PF18558.1 GAM22890.1 - 0.0025 17.7 0.2 0.0067 16.3 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain AAA_16 PF13191.6 GAM22890.1 - 0.16 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain zf-4CXXC_R1 PF10497.9 GAM22891.1 - 0.00084 19.5 9.4 0.0039 17.4 9.4 2.2 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Ibs_toxin PF13956.6 GAM22893.1 - 0.18 11.9 0.9 0.3 11.1 0.9 1.3 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Sugarporin_N PF11471.8 GAM22893.1 - 0.31 11.0 1.6 4.7 7.3 1.6 2.2 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Ctf8 PF09696.10 GAM22894.1 - 6e-08 33.1 0.8 6e-08 33.1 0.8 2.0 2 1 1 3 3 3 1 Ctf8 TFIIF_alpha PF05793.12 GAM22894.1 - 1.2 7.6 8.8 1.6 7.2 8.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bromodomain PF00439.25 GAM22895.1 - 2.2e-15 56.5 0.1 5.3e-15 55.2 0.1 1.7 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 GAM22895.1 - 6.9e-06 25.9 1.2 6.9e-06 25.9 1.2 2.4 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 GAM22895.1 - 0.00057 19.4 2.4 0.00057 19.4 2.4 2.1 2 0 0 2 2 2 1 PHD-finger SPX PF03105.19 GAM22895.1 - 0.66 9.8 13.9 1 9.2 13.9 1.3 1 0 0 1 1 1 0 SPX domain SANTA PF09133.10 GAM22895.1 - 0.85 10.1 4.2 41 4.8 0.0 2.6 2 0 0 2 2 2 0 SANTA (SANT Associated) DUF3573 PF12097.8 GAM22895.1 - 4.5 6.0 6.5 7.9 5.2 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Cauli_AT PF03233.13 GAM22895.1 - 5.7 6.8 7.4 2.2 8.2 3.1 2.3 2 0 0 2 2 2 0 Aphid transmission protein G6PD_C PF02781.16 GAM22896.1 - 4.5e-111 370.7 0.0 6.3e-111 370.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GAM22896.1 - 3.9e-54 184.0 0.1 7.1e-54 183.1 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GSIII_N PF12437.8 GAM22897.1 - 5.9e-70 234.1 0.0 1e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 GAM22897.1 - 4.7e-40 136.1 0.2 1.1e-39 134.9 0.2 1.7 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 GAM22897.1 - 1.5e-18 66.9 0.0 2.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain AATase PF07247.12 GAM22898.1 - 1.5e-17 63.3 0.1 2.5e-17 62.6 0.1 1.3 2 0 0 2 2 2 1 Alcohol acetyltransferase Condensation PF00668.20 GAM22898.1 - 1.3e-10 40.6 0.4 1.6e-08 33.6 0.2 2.2 2 0 0 2 2 2 2 Condensation domain CUE PF02845.16 GAM22899.1 - 9.6e-08 31.6 0.1 2.5e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 CUE domain DUF489 PF04356.12 GAM22899.1 - 0.11 12.5 0.7 3.1 7.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF489) DUF1296 PF06972.11 GAM22899.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) DUF3439 PF11921.8 GAM22899.1 - 2 8.4 28.1 2.7 8.0 8.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Tmpp129 PF10272.9 GAM22900.1 - 9.2e-10 38.3 16.9 5.8e-09 35.7 15.8 2.2 1 1 1 2 2 2 1 Putative transmembrane protein precursor Menin PF05053.13 GAM22900.1 - 0.12 10.7 7.1 0.23 9.8 7.1 1.4 1 0 0 1 1 1 0 Menin DHHW PF14286.6 GAM22900.1 - 2.3 7.4 7.7 4.1 6.6 7.7 1.3 1 0 0 1 1 1 0 DHHW protein Suf PF05843.14 GAM22900.1 - 7.6 6.4 14.2 1.1 9.2 8.2 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PGAP1 PF07819.13 GAM22901.1 - 1.1e-71 241.2 0.0 2e-71 240.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 GAM22901.1 - 0.016 15.1 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 GAM22901.1 - 0.017 15.7 0.0 0.053 14.1 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Med3 PF11593.8 GAM22901.1 - 0.027 13.7 2.7 0.059 12.6 2.7 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal polyprenyl_synt PF00348.17 GAM22902.1 - 5.1e-70 235.4 0.1 7.5e-70 234.9 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 GAM22902.1 - 0.025 14.2 0.2 0.025 14.2 0.2 1.8 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Pkinase_Tyr PF07714.17 GAM22903.1 - 2.4e-60 204.0 0.0 4.5e-60 203.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM22903.1 - 1.2e-51 175.7 0.0 1.2e-51 175.7 0.0 1.9 2 0 0 2 2 1 1 Protein kinase domain SH2 PF00017.24 GAM22903.1 - 2.1e-11 43.7 1.5 4.1e-11 42.8 0.0 2.3 2 0 0 2 2 1 1 SH2 domain APH PF01636.23 GAM22903.1 - 0.044 13.7 0.0 0.044 13.7 0.0 2.3 2 0 0 2 2 1 0 Phosphotransferase enzyme family TFIIA PF03153.13 GAM22903.1 - 0.06 13.4 36.0 0.1 12.6 36.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 GAM22903.1 - 0.27 10.0 14.3 0.36 9.6 14.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain AbiH PF14253.6 GAM22903.1 - 0.32 10.8 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Sin_N PF04801.13 GAM22903.1 - 0.37 10.0 22.4 0.56 9.4 22.4 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region Macoilin PF09726.9 GAM22903.1 - 0.93 8.0 13.7 1.3 7.5 13.7 1.2 1 0 0 1 1 1 0 Macoilin family Sec62 PF03839.16 GAM22903.1 - 1.4 8.4 11.1 2.4 7.6 11.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 GAM22903.1 - 1.4 7.6 22.4 2 7.1 22.4 1.2 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 GAM22903.1 - 1.6 7.5 16.0 2.8 6.7 16.0 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Spore_coat_CotO PF14153.6 GAM22903.1 - 1.7 8.6 26.7 3.2 7.7 26.7 1.4 1 0 0 1 1 1 0 Spore coat protein CotO SRP-alpha_N PF04086.13 GAM22903.1 - 1.9 8.3 26.9 3.6 7.4 26.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Zip PF02535.22 GAM22903.1 - 2 7.6 12.4 3.1 6.9 12.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Endostatin PF06482.11 GAM22903.1 - 2.2 7.7 15.5 4.7 6.6 15.5 1.6 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CDC45 PF02724.14 GAM22903.1 - 2.2 6.4 13.5 3.2 6.0 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.11 GAM22903.1 - 4.1 5.8 17.3 5.5 5.3 17.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Otopetrin PF03189.13 GAM22903.1 - 4.9 5.9 6.4 0.91 8.3 3.2 1.5 2 0 0 2 2 2 0 Otopetrin Ndc1_Nup PF09531.10 GAM22903.1 - 6.2 5.4 15.2 9.3 4.8 15.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PNISR PF15996.5 GAM22903.1 - 7.4 6.8 22.9 12 6.1 22.9 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SLC12 PF03522.15 GAM22903.1 - 10 5.1 18.9 19 4.2 18.9 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Ank_4 PF13637.6 GAM22904.1 - 4.5e-44 148.3 9.5 1.2e-11 44.9 0.1 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM22904.1 - 1.1e-43 147.7 0.1 9.9e-15 54.9 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM22904.1 - 1.1e-37 127.6 0.8 5.8e-10 39.2 0.0 4.9 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM22904.1 - 5.5e-31 103.1 0.3 2.5e-06 27.4 0.0 6.1 5 0 0 5 5 5 5 Ankyrin repeat DHHC PF01529.20 GAM22904.1 - 5.1e-30 104.3 9.6 5.1e-30 104.3 9.6 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.30 GAM22904.1 - 9.5e-28 95.4 6.2 7.8e-07 29.3 0.1 6.7 6 1 0 6 6 6 4 Ankyrin repeat VCH_CASS14 PF18315.1 GAM22904.1 - 0.15 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain IGFBP PF00219.18 GAM22904.1 - 1.7 9.4 8.9 3.2 8.5 5.5 2.4 2 0 0 2 2 2 0 Insulin-like growth factor binding protein CAF1 PF04857.20 GAM22906.1 - 8.1e-70 235.5 12.8 2.8e-69 233.7 12.8 1.7 1 1 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 GAM22906.1 - 0.00019 21.2 0.1 0.084 12.6 0.1 2.4 2 0 0 2 2 2 2 3'-5' exonuclease zf-CCCH_4 PF18044.1 GAM22906.1 - 0.016 15.0 1.6 0.024 14.5 1.6 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 GAM22906.1 - 0.035 14.0 0.3 0.053 13.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Myosin_head PF00063.21 GAM22908.1 - 2.6e-280 931.5 4.7 3.2e-280 931.2 4.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAM22908.1 - 1.5e-38 132.3 4.6 2.9e-38 131.4 4.6 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 GAM22908.1 - 1e-09 37.3 5.4 0.00029 20.4 0.0 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif RsgA_GTPase PF03193.16 GAM22908.1 - 0.0069 16.3 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 GAM22908.1 - 0.092 13.0 0.0 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAM22908.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Notch PF00066.17 GAM22910.1 - 1.3e-38 131.1 107.2 1.9e-07 31.4 5.7 7.6 7 1 0 7 7 7 6 LNR domain TMEM154 PF15102.6 GAM22911.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family PulG PF11773.8 GAM22911.1 - 0.064 13.1 0.5 0.064 13.1 0.5 1.8 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin Cadherin_C_2 PF16492.5 GAM22911.1 - 0.075 13.8 3.4 0.21 12.3 2.3 2.2 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Orf78 PF06024.12 GAM22911.1 - 0.098 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) EphA2_TM PF14575.6 GAM22911.1 - 0.21 12.5 4.1 0.38 11.7 4.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 GAM22911.1 - 0.68 9.6 4.4 0.19 11.3 1.1 1.8 2 0 0 2 2 2 0 Baculovirus 11 kDa family HemY_N PF07219.13 GAM22911.1 - 2.2 8.5 3.8 1.5 9.0 1.3 1.8 2 0 0 2 2 2 0 HemY protein N-terminus Syndecan PF01034.20 GAM22911.1 - 7.2 6.6 7.2 13 5.7 7.2 1.4 1 0 0 1 1 1 0 Syndecan domain UPF0556 PF10572.9 GAM22912.1 - 1.1e-13 50.9 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 ADK_lid PF05191.14 GAM22913.1 - 0.00035 20.5 0.1 0.00049 20.0 0.1 1.2 1 0 0 1 1 1 1 Adenylate kinase, active site lid RRM_1 PF00076.22 GAM22914.1 - 0.057 13.2 0.0 0.8 9.6 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3Ka PF00613.20 GAM22915.1 - 2e-25 89.3 3.2 1.4e-23 83.2 2.5 2.7 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 GAM22915.1 - 8.8e-19 68.3 8.3 1e-16 61.6 0.8 3.8 3 1 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 GAM22915.1 - 8.1e-15 54.7 9.1 8.1e-15 54.7 9.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger DUF4135 PF13575.6 GAM22915.1 - 1.6e-05 24.4 0.0 2.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) BET PF17035.5 GAM22915.1 - 0.074 13.2 0.0 0.32 11.2 0.0 2.1 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation FYVE_2 PF02318.16 GAM22915.1 - 1 9.6 12.7 2.9 8.1 9.0 3.1 2 1 1 3 3 3 0 FYVE-type zinc finger DZR PF12773.7 GAM22915.1 - 1.3 9.1 7.0 1.7e+02 2.4 7.2 2.6 1 1 1 2 2 2 0 Double zinc ribbon NUDE_C PF04880.13 GAM22915.1 - 2.9 8.3 8.3 6.6 7.2 8.3 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF4615 PF15393.6 GAM22916.1 - 2.7e-10 41.0 13.3 2.7e-10 41.0 13.3 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4615) SSP160 PF06933.11 GAM22916.1 - 0.6 8.2 8.3 0.73 8.0 8.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sh_2 PF17512.2 GAM22916.1 - 3.3 7.5 7.5 1.2 8.9 4.6 1.7 2 0 0 2 2 2 0 Metapneumovirus Small hydrophobic protein UQ_con PF00179.26 GAM22917.1 - 3.8e-46 156.2 0.1 1.2e-44 151.4 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme TPR_1 PF00515.28 GAM22918.1 - 5.5e-18 64.0 6.0 4.3e-07 29.5 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM22918.1 - 1.6e-16 59.1 2.9 7.7e-07 28.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat SGTA_dimer PF16546.5 GAM22918.1 - 1.9e-14 53.1 0.1 4.6e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 GAM22918.1 - 5.8e-14 51.0 5.7 4.9e-06 26.2 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM22918.1 - 8.1e-12 44.7 8.5 3.5e-05 23.9 1.6 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM22918.1 - 5.5e-10 38.8 11.7 0.00037 20.1 0.2 3.5 1 1 2 3 3 3 3 TPR repeat TPR_14 PF13428.6 GAM22918.1 - 1.1e-07 32.1 0.0 0.0029 18.3 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM22918.1 - 4.1e-07 30.5 0.6 2.9e-06 27.8 0.6 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM22918.1 - 9.3e-07 29.3 0.6 4.1e-06 27.2 0.2 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM22918.1 - 1.3e-06 28.0 0.9 0.11 12.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM22918.1 - 5.9e-06 26.6 2.4 0.0083 16.7 0.1 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM22918.1 - 2.5e-05 24.5 1.2 9.4e-05 22.6 1.0 2.1 2 1 0 2 2 1 1 Tetratricopeptide repeat DUF3856 PF12968.7 GAM22918.1 - 0.0014 18.7 4.0 0.025 14.7 1.9 2.9 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) STI1 PF17830.1 GAM22918.1 - 0.0035 17.2 9.5 0.013 15.5 9.5 2.0 1 1 0 1 1 1 1 STI1 domain TPR_10 PF13374.6 GAM22918.1 - 0.0075 16.1 3.9 1.4 8.9 1.9 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM22918.1 - 0.01 15.1 0.3 0.021 14.1 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Duffy_binding PF05424.11 GAM22918.1 - 0.014 15.4 0.2 0.023 14.7 0.2 1.4 1 0 0 1 1 1 0 Duffy binding domain TOM20_plant PF06552.12 GAM22918.1 - 0.054 13.2 0.6 0.31 10.8 0.3 2.4 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DUF627 PF04781.12 GAM22918.1 - 0.064 13.3 1.1 0.59 10.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF627) ANAPC3 PF12895.7 GAM22918.1 - 0.082 13.1 2.4 0.16 12.3 2.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 PUMA PF15826.5 GAM22918.1 - 0.093 12.9 0.3 0.97 9.6 0.0 2.1 2 0 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Wzy_C_2 PF11846.8 GAM22918.1 - 0.097 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF2281 PF10047.9 GAM22918.1 - 0.098 13.4 0.1 0.33 11.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) TPR_20 PF14561.6 GAM22918.1 - 0.14 12.5 1.1 0.7 10.3 0.3 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAM22918.1 - 0.18 12.0 0.0 0.97 9.6 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat GerD PF17898.1 GAM22918.1 - 1.8 8.5 6.9 1.4 8.9 4.4 2.2 2 1 0 2 2 2 0 Spore germination GerD central core domain TPR_14 PF13428.6 GAM22919.1 - 3.2e-10 40.0 13.8 0.41 11.6 0.0 8.4 7 3 3 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM22919.1 - 7.4e-10 39.2 9.3 0.19 12.3 0.0 6.9 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM22919.1 - 3e-05 24.6 3.1 0.15 12.7 0.0 4.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM22919.1 - 3.2e-05 24.0 0.5 0.051 14.0 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM22919.1 - 0.00086 19.3 12.1 13 6.3 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM22919.1 - 0.037 14.1 21.5 1.3 9.3 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat PknG_TPR PF16918.5 GAM22919.1 - 0.06 12.1 0.2 4.9 5.8 0.1 2.5 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat GRIM-19 PF06212.12 GAM22921.1 - 6.7e-16 58.4 0.0 1.9e-15 57.0 0.0 1.6 1 1 1 2 2 2 1 GRIM-19 protein Coiled PF05710.12 GAM22922.1 - 0.0098 16.7 5.7 0.012 16.4 5.7 1.2 1 0 0 1 1 1 1 Coiled coil TMEM40 PF15817.5 GAM22922.1 - 0.14 11.9 0.2 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 40 family DUF3482 PF11981.8 GAM22922.1 - 0.51 9.7 2.1 0.54 9.6 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Phosphonate-bd PF12974.7 GAM22923.1 - 3.8e-20 72.5 0.0 6.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 GAM22923.1 - 0.0028 17.6 0.0 0.0068 16.4 0.0 1.7 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 GAM22923.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 WD40 PF00400.32 GAM22924.1 - 4.2e-46 154.0 9.4 3.3e-08 34.1 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM22924.1 - 2e-14 53.6 0.1 0.0054 17.0 0.0 5.4 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM22924.1 - 6.8e-07 28.6 0.0 0.37 9.7 0.0 3.7 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 GAM22924.1 - 0.00012 21.5 0.3 2.1 7.6 0.0 3.2 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 GAM22924.1 - 0.01 14.2 0.0 0.093 11.0 0.0 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 GAM22924.1 - 0.026 13.2 1.1 0.87 8.2 0.1 3.2 3 1 1 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 GAM22924.1 - 0.065 12.5 0.1 2.5 7.4 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain PD40 PF07676.12 GAM22924.1 - 0.11 12.5 0.4 8 6.5 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat EGF_2 PF07974.13 GAM22925.1 - 0.00093 19.5 16.0 0.00093 19.5 16.0 2.0 2 0 0 2 2 2 1 EGF-like domain EB PF01683.18 GAM22925.1 - 0.0022 18.3 2.4 0.0049 17.1 2.4 1.5 1 0 0 1 1 1 1 EB module EGF_Tenascin PF18720.1 GAM22925.1 - 0.024 14.7 8.3 0.05 13.7 8.3 1.5 1 0 0 1 1 1 0 Tenascin EGF domain EphA2_TM PF14575.6 GAM22925.1 - 0.14 13.0 2.1 0.35 11.8 2.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Abhydrolase_1 PF00561.20 GAM22926.1 - 8.9e-18 64.9 0.1 1.7e-11 44.3 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM22926.1 - 2.8e-16 59.5 0.0 1.5e-10 40.8 0.0 2.4 1 1 2 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GAM22926.1 - 1.1e-09 38.4 0.0 1.8e-05 24.7 0.0 3.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAM22926.1 - 4.3e-09 36.1 0.0 1.2e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 GAM22926.1 - 2.5e-08 33.8 0.0 8.7e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF818 PF05677.12 GAM22926.1 - 7.6e-07 28.4 0.0 1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) AXE1 PF05448.12 GAM22926.1 - 8.1e-07 28.0 0.1 0.0097 14.6 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 GAM22926.1 - 5.7e-06 26.4 0.0 0.034 14.0 0.0 2.1 1 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 GAM22926.1 - 7e-05 23.5 0.0 0.00011 22.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 GAM22926.1 - 0.00048 19.9 0.0 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 GAM22926.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.20 GAM22926.1 - 0.0016 18.1 0.0 0.0048 16.6 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 GAM22926.1 - 0.0043 16.9 0.0 0.0092 15.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 GAM22926.1 - 0.0061 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.7 GAM22926.1 - 0.011 15.5 0.0 0.43 10.3 0.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 GAM22926.1 - 0.023 14.4 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Peptidase_S28 PF05577.12 GAM22926.1 - 0.024 13.4 0.0 0.054 12.3 0.0 1.4 1 1 0 1 1 1 0 Serine carboxypeptidase S28 Lipase_3 PF01764.25 GAM22926.1 - 0.038 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) GSu_C4xC__C2xCH PF09698.10 GAM22926.1 - 0.049 14.4 0.3 0.086 13.6 0.3 1.4 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) DUF2974 PF11187.8 GAM22926.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 GAM22926.1 - 0.19 11.8 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Sterol_MT_C PF08498.10 GAM22927.1 - 1e-20 73.8 0.0 1.8e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GAM22927.1 - 7.4e-16 58.6 0.0 1.8e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAM22927.1 - 1.4e-15 57.3 0.0 2.5e-15 56.5 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 GAM22927.1 - 5.1e-15 56.0 0.0 1.2e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM22927.1 - 1.8e-14 53.8 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM22927.1 - 7.9e-13 48.6 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM22927.1 - 9.9e-07 29.4 0.0 2.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM22927.1 - 1.5e-05 24.5 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 GAM22927.1 - 4.2e-05 23.4 0.0 6.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 GAM22927.1 - 0.058 13.4 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 GAM22927.1 - 0.063 13.4 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 GAM22927.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MBOAT_2 PF13813.6 GAM22927.1 - 0.12 12.7 0.1 12 6.2 0.0 2.3 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family CHCH PF06747.13 GAM22928.1 - 7.7e-05 22.7 4.1 0.00011 22.2 4.1 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 GAM22928.1 - 0.0076 16.5 2.7 0.012 15.9 2.7 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 GAM22928.1 - 0.046 13.7 4.3 0.07 13.2 4.3 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX6B PF02297.17 GAM22928.1 - 0.062 13.5 0.6 0.25 11.6 0.6 1.9 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb PCI PF01399.27 GAM22929.1 - 3.2e-25 88.7 3.2 4.3e-25 88.3 0.9 2.4 2 0 0 2 2 2 1 PCI domain TPR_8 PF13181.6 GAM22929.1 - 0.0028 17.8 8.5 0.95 9.8 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM22929.1 - 0.0044 17.0 0.4 22 5.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM22929.1 - 0.013 15.3 3.3 0.61 10.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM22929.1 - 0.031 13.9 0.6 2.8 7.7 0.1 3.5 3 0 0 3 3 3 0 TPR repeat DpnI_C PF17726.1 GAM22929.1 - 0.068 13.3 1.9 0.63 10.2 0.1 2.8 2 0 0 2 2 2 0 Dam-replacing HTH domain TPR_2 PF07719.17 GAM22929.1 - 0.22 11.7 4.3 4 7.8 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 GAM22930.1 - 3.5e-12 45.9 0.0 5.4e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM22930.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pkinase PF00069.25 GAM22931.1 - 7.6e-60 202.5 0.0 1.2e-59 201.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22931.1 - 1.9e-39 135.5 0.0 2.8e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM22931.1 - 0.018 13.8 0.0 0.018 13.8 0.0 3.8 2 1 0 2 2 2 0 Fungal protein kinase DUF3419 PF11899.8 GAM22932.1 - 2.5e-17 63.2 0.0 5.3e-17 62.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_12 PF08242.12 GAM22932.1 - 0.0014 19.4 0.0 0.27 12.0 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM22932.1 - 0.0023 18.6 0.0 0.087 13.5 0.0 3.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM22932.1 - 0.016 15.8 0.0 0.053 14.2 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain CheR PF01739.18 GAM22932.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PBS_linker_poly PF00427.21 GAM22932.1 - 0.12 12.4 0.3 5.8 7.0 0.0 3.0 2 1 1 3 3 3 0 Phycobilisome Linker polypeptide WW PF00397.26 GAM22933.1 - 6e-20 71.0 6.4 4.6e-11 42.6 0.2 2.5 2 0 0 2 2 2 2 WW domain Arm PF00514.23 GAM22933.1 - 7.3e-18 63.9 49.6 0.00014 21.8 0.2 15.4 17 0 0 17 17 17 7 Armadillo/beta-catenin-like repeat FYVE PF01363.21 GAM22933.1 - 7.1e-14 51.7 11.3 1.9e-13 50.3 11.3 1.8 1 0 0 1 1 1 1 FYVE zinc finger HEAT_2 PF13646.6 GAM22933.1 - 0.0036 17.7 7.9 3.8 8.0 0.1 6.7 7 1 0 7 7 7 1 HEAT repeats V-ATPase_H_C PF11698.8 GAM22933.1 - 0.0037 17.3 0.1 0.0037 17.3 0.1 6.3 6 3 3 9 9 9 1 V-ATPase subunit H DUF3361 PF11841.8 GAM22933.1 - 0.0066 16.4 1.5 0.0066 16.4 1.5 8.0 7 4 2 10 10 10 3 Domain of unknown function (DUF3361) HEAT_EZ PF13513.6 GAM22933.1 - 0.013 16.0 5.6 7 7.3 0.3 5.9 4 1 1 5 5 5 0 HEAT-like repeat HEAT PF02985.22 GAM22933.1 - 0.49 10.8 16.5 14 6.2 0.1 8.2 8 0 0 8 8 8 0 HEAT repeat Atx10homo_assoc PF09759.9 GAM22933.1 - 0.52 10.4 13.8 1.3 9.1 0.7 5.8 5 1 1 6 6 6 0 Spinocerebellar ataxia type 10 protein domain Fez1 PF06818.15 GAM22934.1 - 0.0005 20.6 23.3 0.0005 20.6 23.3 6.1 3 2 1 5 5 5 1 Fez1 DUF724 PF05266.14 GAM22934.1 - 0.0054 16.6 15.6 0.0054 16.6 15.6 8.5 4 2 4 8 8 8 2 Protein of unknown function (DUF724) FliJ PF02050.16 GAM22934.1 - 0.015 15.5 5.1 0.015 15.5 5.1 7.8 4 1 4 8 8 8 0 Flagellar FliJ protein KicB PF03882.14 GAM22934.1 - 0.028 14.6 0.5 0.14 12.4 0.5 2.2 1 0 0 1 1 1 0 MukF winged-helix domain DUF3800 PF12686.7 GAM22934.1 - 0.046 14.3 2.8 16 6.2 2.8 4.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) PI3K_P85_iSH2 PF16454.5 GAM22934.1 - 0.52 9.9 0.0 0.52 9.9 0.0 9.3 5 2 4 9 9 9 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Transthyretin PF00576.21 GAM22934.1 - 0.63 10.7 2.9 3.4 8.4 0.1 3.3 2 0 0 2 2 2 0 HIUase/Transthyretin family ATG16 PF08614.11 GAM22934.1 - 3.6 7.8 118.9 0.14 12.4 27.5 7.6 3 3 4 7 7 7 0 Autophagy protein 16 (ATG16) NDT80_PhoG PF05224.12 GAM22935.1 - 0.07 13.3 13.8 0.082 13.1 13.8 1.1 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family DUF1635 PF07795.11 GAM22935.1 - 1.8 8.4 7.0 1.9 8.3 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SNF2_N PF00176.23 GAM22936.1 - 2.5e-25 88.9 0.0 4.6e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM22936.1 - 2.4e-12 47.2 0.0 9.6e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM22936.1 - 4.8e-07 29.9 0.5 1.5e-05 25.1 0.0 3.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 GAM22936.1 - 0.0058 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain DDDD PF10161.9 GAM22936.1 - 1.4 8.8 6.1 4.9 7.0 6.1 2.0 1 0 0 1 1 1 0 Putative mitochondrial precursor protein FNIP PF05725.12 GAM22937.1 - 1.1e-18 67.1 3.9 3.5e-08 33.5 0.0 6.2 4 2 1 6 6 6 4 FNIP Repeat Arf PF00025.21 GAM22938.1 - 7.9e-42 142.7 0.0 9.7e-30 103.3 0.1 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAM22938.1 - 5.9e-08 32.9 0.1 1.3e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM22938.1 - 0.0025 17.4 0.1 0.0052 16.4 0.1 1.6 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 GAM22938.1 - 0.0027 17.2 0.0 0.015 14.7 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA PF00004.29 GAM22938.1 - 0.011 16.1 0.0 0.066 13.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAM22938.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAM22938.1 - 0.046 13.6 0.1 1.4 8.8 0.1 2.3 1 1 0 1 1 1 0 NACHT domain SRP54 PF00448.22 GAM22938.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Dicty_REP PF05086.12 GAM22938.1 - 1.7 6.5 10.7 2.6 5.9 10.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Retinal PF15449.6 GAM22938.1 - 8.1 4.1 20.0 11 3.7 20.0 1.0 1 0 0 1 1 1 0 Retinal protein SUIM_assoc PF16619.5 GAM22939.1 - 1.1e-05 25.4 14.9 0.015 15.3 1.8 2.6 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GAM22939.1 - 3.7e-05 23.5 21.8 0.00031 20.4 3.3 2.2 2 0 0 2 2 2 2 Spt20 family Rad60-SLD_2 PF13881.6 GAM22939.1 - 5.7e-05 23.2 0.1 0.00028 21.0 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2722 PF10846.8 GAM22939.1 - 0.00076 18.5 17.5 0.0025 16.9 1.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) TFIIA PF03153.13 GAM22939.1 - 0.0013 18.9 16.0 0.0091 16.0 3.4 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit COG4 PF08318.12 GAM22939.1 - 0.0031 16.6 1.8 0.0046 16.1 1.8 1.2 1 0 0 1 1 1 1 COG4 transport protein DUF4834 PF16118.5 GAM22939.1 - 0.0048 17.8 8.7 0.11 13.5 0.3 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) GET2 PF08690.10 GAM22939.1 - 0.05 13.3 5.7 0.071 12.8 5.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Comm PF15957.5 GAM22939.1 - 0.067 13.5 1.2 0.74 10.2 0.1 2.4 2 0 0 2 2 2 0 Commissureless Mlh1_C PF16413.5 GAM22939.1 - 0.099 12.0 3.9 3.9 6.8 0.1 2.1 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus CSG2 PF16965.5 GAM22939.1 - 0.12 11.3 3.9 0.73 8.7 1.4 2.1 2 0 0 2 2 2 0 Ceramide synthase regulator PAP2_3 PF14378.6 GAM22939.1 - 0.16 11.6 8.2 1 9.0 4.7 2.8 2 1 1 3 3 3 0 PAP2 superfamily TERB2 PF15101.6 GAM22939.1 - 0.22 11.5 11.0 1.3 9.1 2.4 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 GTA_holin_3TM PF11351.8 GAM22939.1 - 0.27 11.8 3.8 1.4 9.5 0.2 2.5 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release DUF702 PF05142.12 GAM22939.1 - 0.72 10.3 8.5 3.6 8.1 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF3371 PF11851.8 GAM22939.1 - 0.74 10.9 10.6 4.5 8.4 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Porph_ging PF09697.10 GAM22939.1 - 1.4 9.5 4.6 1.4 9.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) RLL PF10036.9 GAM22939.1 - 1.5 8.7 9.6 3 7.6 0.9 2.2 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DUF2367 PF10164.9 GAM22939.1 - 3.2 8.3 6.7 3.1 8.3 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) CPSF100_C PF13299.6 GAM22939.1 - 3.7 7.7 5.7 27 4.9 0.2 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Roughex PF06020.11 GAM22939.1 - 4 6.4 8.9 0.86 8.6 0.6 2.1 2 0 0 2 2 2 0 Drosophila roughex protein MPM1 PF17234.2 GAM22939.1 - 5.7 7.2 14.2 0.66 10.2 1.9 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 ANAPC_CDC26 PF10471.9 GAM22939.1 - 6.6 7.6 32.0 0.33 11.8 7.2 2.7 3 0 0 3 3 2 0 Anaphase-promoting complex APC subunit CDC26 Ribonuclease_T2 PF00445.18 GAM22940.1 - 2.9e-49 167.8 0.0 3.4e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family WD40 PF00400.32 GAM22942.1 - 4.6e-37 125.4 22.4 2e-05 25.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM22942.1 - 4e-12 46.3 0.0 0.092 13.0 0.0 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM22942.1 - 0.00016 21.1 0.0 0.00052 19.4 0.0 2.1 1 1 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 GAM22942.1 - 0.083 11.5 0.1 8.5 4.9 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 CRF PF00473.17 GAM22942.1 - 0.64 10.1 2.0 1.2 9.3 2.0 1.3 1 0 0 1 1 1 0 Corticotropin-releasing factor family Adap_comp_sub PF00928.21 GAM22943.1 - 1e-90 303.7 0.2 1.3e-90 303.3 0.2 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAM22943.1 - 6.7e-10 39.1 1.3 1.2e-09 38.3 1.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 GAM22943.1 - 0.0098 15.4 0.2 0.022 14.2 0.1 1.6 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain Longin PF13774.6 GAM22943.1 - 0.019 15.0 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain Glyco_hydro_2_C PF02836.17 GAM22943.1 - 0.044 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Sec1 PF00995.23 GAM22944.1 - 1e-20 74.5 1.4 5.9e-20 72.0 1.4 1.9 1 1 0 1 1 1 1 Sec1 family Ribosomal_S3Ae PF01015.18 GAM22945.1 - 1.7e-83 279.2 7.0 2.1e-83 278.9 7.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF3130 PF11328.8 GAM22945.1 - 0.0045 17.2 0.8 3.6 7.9 0.3 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3130 Abhydro_lipase PF04083.16 GAM22945.1 - 0.014 14.9 0.0 0.052 13.1 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ank_2 PF12796.7 GAM22946.1 - 3.6e-30 104.4 5.6 1.2e-11 45.0 0.2 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAM22946.1 - 3.5e-20 71.5 4.3 4.1e-05 23.8 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 GAM22946.1 - 3.9e-20 71.9 2.8 1.1e-06 29.1 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM22946.1 - 4.3e-17 60.5 2.0 0.00055 20.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GAM22946.1 - 4.6e-16 58.7 4.0 1e-08 35.2 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) CBM49 PF09478.10 GAM22947.1 - 4.1e-17 62.3 1.8 7.9e-17 61.4 1.1 1.8 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 TRAP_beta PF05753.14 GAM22947.1 - 0.015 14.7 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) GH115_C PF17829.1 GAM22947.1 - 0.09 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain DUF908 PF06012.12 GAM22948.1 - 0.0074 15.7 4.3 0.0078 15.7 4.3 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) NST1 PF13945.6 GAM22948.1 - 1.9 8.5 15.2 2.7 8.0 15.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator EVI2A PF05399.11 GAM22948.1 - 5.5 6.5 14.1 7.7 6.0 14.1 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) GST_C_3 PF14497.6 GAM22950.1 - 5.1e-21 74.7 0.1 6.6e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM22950.1 - 1.8e-08 34.4 0.0 2.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM22950.1 - 0.00063 19.7 0.0 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 GAM22950.1 - 0.1 12.4 0.1 0.35 10.7 0.0 1.9 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain CPSF73-100_C PF11718.8 GAM22951.1 - 2.1e-60 203.9 3.3 4.7e-60 202.8 3.3 1.6 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 GAM22951.1 - 2.6e-29 101.7 0.8 6e-29 100.5 0.0 2.1 2 1 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 GAM22951.1 - 9.9e-20 70.8 0.0 9.9e-20 70.8 0.0 3.6 4 1 0 4 4 4 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 GAM22951.1 - 1.3e-17 64.4 0.0 2.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 GAM22951.1 - 1.4e-15 57.0 0.1 3.8e-15 55.6 0.1 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 GAM22951.1 - 2.9e-08 33.5 0.8 2.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 GAM22951.1 - 8.2e-07 28.5 0.0 2.6e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 GAM22951.1 - 4.6e-06 26.6 0.0 2.3e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Myc_N PF01056.18 GAM22951.1 - 0.015 15.3 1.7 0.015 15.3 1.7 1.8 2 0 0 2 2 2 0 Myc amino-terminal region Cyclin PF08613.11 GAM22952.1 - 1.4e-05 25.6 7.2 1.4e-05 25.6 7.2 4.3 2 2 0 2 2 2 1 Cyclin TMEM234 PF10639.9 GAM22952.1 - 0.016 15.2 0.5 6.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Putative transmembrane family 234 DUF3523 PF12037.8 GAM22952.1 - 2.6 7.4 7.9 4.8 6.5 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) PP2C_2 PF13672.6 GAM22953.1 - 0.0019 17.9 0.1 0.46 10.1 0.0 3.0 2 1 1 3 3 3 2 Protein phosphatase 2C Maf PF02545.14 GAM22953.1 - 0.02 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Maf-like protein SpoIIE PF07228.12 GAM22953.1 - 0.074 13.0 0.1 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) CBS PF00571.28 GAM22954.1 - 2.9e-26 91.7 2.9 2.1e-09 37.7 0.0 4.0 4 0 0 4 4 4 3 CBS domain CsgG PF03783.14 GAM22955.1 - 0.015 14.6 0.1 0.029 13.7 0.1 1.5 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG PH_8 PF15409.6 GAM22955.1 - 0.037 14.3 0.3 0.1 12.9 0.3 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Citrate_synt PF00285.21 GAM22956.1 - 3.6e-23 82.2 0.0 3e-18 66.0 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 GAM22956.1 - 6.4e-09 35.8 0.0 1.3e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 GAM22956.1 - 0.00076 20.1 0.0 0.0016 19.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 GAM22956.1 - 0.002 17.9 0.0 0.044 13.6 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain SoxG PF04268.12 GAM22956.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family FNIP PF05725.12 GAM22957.1 - 4.2e-63 209.3 16.2 1.6e-11 44.1 2.0 8.6 6 2 1 8 8 8 7 FNIP Repeat Telomerase_RBD PF12009.8 GAM22957.1 - 0.091 12.9 0.1 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Telomerase ribonucleoprotein complex - RNA binding domain DUF1769 PF08588.10 GAM22957.1 - 0.22 11.7 1.5 8.7 6.6 0.0 4.2 5 1 0 5 5 5 0 Protein of unknown function (DUF1769) Acetyltransf_1 PF00583.25 GAM22958.1 - 2e-15 57.0 0.0 2.7e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM22958.1 - 1.1e-10 41.8 0.0 1.7e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM22958.1 - 1.3e-08 34.7 0.1 2.3e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAM22958.1 - 3.3e-08 33.5 0.1 5.1e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAM22958.1 - 0.0023 17.6 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM22958.1 - 0.0052 16.9 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAM22958.1 - 0.032 14.9 0.0 0.041 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM22958.1 - 0.07 13.3 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM22958.1 - 0.093 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SSP160 PF06933.11 GAM22958.1 - 0.41 8.8 4.7 0.45 8.6 4.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Erf4 PF10256.9 GAM22959.1 - 0.014 15.5 0.1 0.023 14.8 0.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family AAA PF00004.29 GAM22960.1 - 3.7e-99 328.3 0.0 4.4e-49 166.3 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM22960.1 - 5.1e-24 83.8 5.9 3.7e-11 42.6 0.4 3.2 2 2 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 GAM22960.1 - 1.8e-20 72.9 0.3 4.8e-20 71.5 0.3 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 GAM22960.1 - 3.3e-15 56.2 0.0 2.8e-06 27.2 0.0 3.2 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAM22960.1 - 2.3e-13 50.6 0.0 7.7e-07 29.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAM22960.1 - 3.1e-13 50.5 1.0 0.00014 22.3 0.0 4.1 3 2 0 3 3 2 2 AAA ATPase domain AAA_5 PF07728.14 GAM22960.1 - 1.2e-11 44.8 0.1 3.8e-06 26.9 0.0 3.4 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAM22960.1 - 8e-11 42.3 0.0 4.5e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAM22960.1 - 1.5e-10 41.5 0.2 0.0035 17.6 0.1 3.9 2 2 1 3 3 3 2 AAA domain CDC48_2 PF02933.17 GAM22960.1 - 7.1e-10 38.5 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 GAM22960.1 - 4.6e-09 36.4 0.0 0.0005 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 GAM22960.1 - 1.1e-08 34.9 0.3 6.4e-06 26.1 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 GAM22960.1 - 2.6e-08 33.4 0.0 0.0025 17.1 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 GAM22960.1 - 1e-07 31.5 0.5 0.0096 15.3 0.1 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAM22960.1 - 1.1e-07 32.5 0.0 0.015 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAM22960.1 - 1.1e-07 32.1 0.0 0.0078 16.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 GAM22960.1 - 4.5e-07 30.0 0.3 0.058 13.3 0.1 3.4 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 GAM22960.1 - 1.1e-06 28.5 0.1 0.055 13.2 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein Viral_helicase1 PF01443.18 GAM22960.1 - 1.5e-06 28.1 0.0 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 GAM22960.1 - 1.9e-06 28.4 0.0 0.015 15.8 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.18 GAM22960.1 - 2.7e-06 27.4 0.0 0.015 15.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_25 PF13481.6 GAM22960.1 - 2.8e-06 27.0 1.6 0.95 9.0 0.0 4.0 2 2 0 4 4 4 1 AAA domain AAA_28 PF13521.6 GAM22960.1 - 4.7e-06 26.9 0.0 0.18 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 GAM22960.1 - 5.6e-06 25.7 0.1 0.031 13.4 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NACHT PF05729.12 GAM22960.1 - 7.9e-06 25.9 0.1 0.31 10.9 0.0 3.4 3 1 0 4 4 4 2 NACHT domain AAA_7 PF12775.7 GAM22960.1 - 9.5e-06 25.2 0.1 0.11 12.0 0.0 3.0 3 1 0 3 3 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAM22960.1 - 1.2e-05 24.7 0.0 0.086 12.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.6 GAM22960.1 - 1.5e-05 25.4 0.0 0.23 11.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 GAM22960.1 - 2.8e-05 24.1 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GAM22960.1 - 3.6e-05 23.5 0.0 0.36 10.5 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain ATPase PF06745.13 GAM22960.1 - 3.6e-05 23.2 0.1 2.9 7.2 0.0 3.4 3 0 0 3 3 3 1 KaiC AAA_24 PF13479.6 GAM22960.1 - 3.9e-05 23.5 0.1 0.098 12.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain Rad17 PF03215.15 GAM22960.1 - 4.7e-05 23.4 0.0 0.44 10.4 0.0 2.6 2 1 0 2 2 2 2 Rad17 P-loop domain NB-ARC PF00931.22 GAM22960.1 - 6.7e-05 22.2 0.0 0.24 10.5 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DUF815 PF05673.13 GAM22960.1 - 0.00015 21.0 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 GAM22960.1 - 0.00021 21.4 0.0 0.47 10.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 GAM22960.1 - 0.00039 20.3 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 GAM22960.1 - 0.0011 19.0 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cytidylate_kin2 PF13189.6 GAM22960.1 - 0.0022 18.1 0.0 0.52 10.4 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family PhoH PF02562.16 GAM22960.1 - 0.0057 16.1 0.3 1.9 7.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein NTPase_1 PF03266.15 GAM22960.1 - 0.0062 16.5 0.1 5.3 6.9 0.0 3.5 3 0 0 3 3 3 0 NTPase SKI PF01202.22 GAM22960.1 - 0.0067 16.6 0.3 6.5 6.9 0.0 2.9 3 0 0 3 3 3 0 Shikimate kinase AAA_19 PF13245.6 GAM22960.1 - 0.0069 16.7 0.6 7.4 6.9 0.1 3.3 3 1 1 4 4 2 0 AAA domain TniB PF05621.11 GAM22960.1 - 0.0072 15.8 0.0 1.7 8.0 0.0 3.6 5 0 0 5 5 4 1 Bacterial TniB protein PduV-EutP PF10662.9 GAM22960.1 - 0.012 15.3 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.6 GAM22960.1 - 0.012 15.4 0.0 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain UFD1 PF03152.14 GAM22960.1 - 0.022 14.3 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 AAA_23 PF13476.6 GAM22960.1 - 0.023 15.2 0.0 12 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAM22960.1 - 0.027 13.7 0.0 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 GAM22960.1 - 0.036 13.3 0.2 1.7 7.8 0.0 3.0 2 2 1 4 4 4 0 KAP family P-loop domain AFG1_ATPase PF03969.16 GAM22960.1 - 0.042 12.8 0.0 4.7 6.0 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Adeno_IVa2 PF02456.15 GAM22960.1 - 0.079 11.7 0.0 11 4.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Cytidylate_kin PF02224.18 GAM22960.1 - 0.086 12.6 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_30 PF13604.6 GAM22960.1 - 0.12 12.1 0.1 21 4.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Hid1 PF12722.7 GAM22961.1 - 2.2e-125 419.7 20.6 3e-106 356.5 12.9 2.8 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 GAM22961.1 - 4.2e-121 405.4 12.0 5e-121 405.1 12.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein FNIP PF05725.12 GAM22962.1 - 1.3e-54 182.1 15.9 8.8e-12 45.0 0.1 9.5 8 2 3 11 11 11 8 FNIP Repeat FNIP PF05725.12 GAM22963.1 - 3e-62 206.6 19.2 1.2e-11 44.5 0.0 8.9 4 3 2 9 9 9 9 FNIP Repeat Coiled PF05710.12 GAM22964.1 - 0.0034 18.2 10.7 0.0043 17.8 10.7 1.2 1 0 0 1 1 1 1 Coiled coil UbiA PF01040.18 GAM22965.1 - 3.7e-46 157.5 14.2 3.7e-46 157.5 14.2 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family DUF3484 PF11983.8 GAM22965.1 - 0.16 13.1 3.9 0.34 12.1 3.9 1.5 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch DUF443 PF04276.12 GAM22965.1 - 1 9.1 4.9 0.66 9.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF443) TFIIA PF03153.13 GAM22965.1 - 3.8 7.4 9.9 5.3 6.9 9.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PP2C PF00481.21 GAM22966.1 - 1.8e-67 227.7 0.1 1.8e-67 227.7 0.1 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C G-alpha PF00503.20 GAM22966.1 - 1.6e-38 132.8 0.0 1.6e-38 132.8 0.0 2.0 2 0 0 2 2 2 1 G-protein alpha subunit AF-4 PF05110.13 GAM22966.1 - 0.091 10.8 25.4 0.14 10.3 25.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Herpes_UL6 PF01763.16 GAM22966.1 - 0.7 8.3 7.1 1.1 7.7 7.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like TMEM119 PF15724.5 GAM22966.1 - 0.72 9.9 14.6 1.6 8.7 14.6 1.6 1 0 0 1 1 1 0 TMEM119 family Hamartin PF04388.12 GAM22966.1 - 0.89 8.1 15.0 1.3 7.6 15.0 1.2 1 0 0 1 1 1 0 Hamartin protein TMEM247 PF15444.6 GAM22966.1 - 1.6 8.7 10.7 4.2 7.3 10.7 1.8 1 0 0 1 1 1 0 Transmembrane protein 247 V_ATPase_I PF01496.19 GAM22966.1 - 5.2 4.9 6.7 9.4 4.0 6.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 GAM22966.1 - 5.9 6.9 12.4 12 5.9 12.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3915 PF13054.6 GAM22966.1 - 6.3 6.8 10.5 20 5.2 10.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) GAGA_bind PF06217.12 GAM22966.1 - 7.2 6.8 18.9 13 6.0 18.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Pkinase PF00069.25 GAM22967.1 - 3.2e-66 223.4 0.1 1.6e-44 152.2 0.5 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22967.1 - 1.8e-27 96.3 0.0 5.5e-22 78.3 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAM22967.1 - 3.1e-06 26.7 0.1 1.4e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAM22967.1 - 0.00012 22.1 0.1 0.0018 18.3 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM22967.1 - 0.00016 20.8 1.5 0.00022 20.3 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 GAM22967.1 - 0.0013 17.8 0.0 0.0037 16.4 0.0 1.7 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 GAM22967.1 - 0.0017 17.2 0.1 0.0017 17.2 0.1 2.2 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAM22967.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IL11 PF07400.11 GAM22967.1 - 0.092 12.4 0.4 0.2 11.3 0.4 1.5 1 0 0 1 1 1 0 Interleukin 11 FSA_C PF10479.9 GAM22967.1 - 0.35 9.0 5.6 0.66 8.0 5.6 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Transketolase_C PF02780.20 GAM22968.1 - 6.7e-43 145.5 0.1 1.2e-42 144.7 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 GAM22968.1 - 9.1e-40 136.2 0.0 1.3e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 GAM22968.1 - 0.019 15.2 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II TRAPPC-Trs85 PF12739.7 GAM22969.1 - 3.7e-53 181.0 4.5 2.2e-47 161.9 3.3 2.4 1 1 1 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 GAM22969.1 - 1.4e-06 26.0 1.1 2.4e-06 25.3 1.1 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 GAM22969.1 - 0.00033 20.9 0.1 0.00081 19.6 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Transglut_C PF00927.22 GAM22969.1 - 0.0098 16.0 0.1 11 6.3 0.0 4.0 2 1 1 3 3 3 1 Transglutaminase family, C-terminal ig like domain TPR_2 PF07719.17 GAM22969.1 - 0.017 15.2 1.5 0.12 12.5 0.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM22969.1 - 0.051 13.3 0.8 0.46 10.2 0.3 2.6 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 GAM22969.1 - 0.077 13.7 0.1 1.1 10.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM22969.1 - 0.094 13.2 0.6 13 6.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 GAM22969.1 - 3.1 7.5 5.1 1.7 8.3 0.9 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 FNIP PF05725.12 GAM22970.1 - 1e-77 256.0 38.7 9.3e-15 54.5 0.4 11.7 9 3 2 11 11 11 10 FNIP Repeat Ribosomal_S17e PF00833.18 GAM22970.1 - 2e-55 185.9 1.0 3.6e-55 185.1 1.0 1.4 1 0 0 1 1 1 1 Ribosomal S17 LRR_4 PF12799.7 GAM22970.1 - 0.053 14.0 18.1 0.13 12.7 0.7 6.0 6 2 1 7 7 7 0 Leucine Rich repeats (2 copies) MFS_1 PF07690.16 GAM22972.1 - 2.3e-17 63.0 41.1 2.3e-17 63.0 41.1 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM22972.1 - 4.3e-10 38.7 31.5 1.2e-09 37.3 30.9 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein Pkinase PF00069.25 GAM22973.1 - 4.9e-77 258.8 0.0 6.5e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM22973.1 - 3.8e-37 128.0 0.0 5.7e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAM22973.1 - 5.5e-05 23.8 0.3 5.5e-05 23.8 0.3 2.5 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 GAM22973.1 - 0.00013 21.4 0.1 0.0025 17.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAM22973.1 - 0.00026 20.1 2.0 0.00048 19.2 2.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 GAM22973.1 - 0.0047 16.6 0.2 2.7 7.6 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 GAM22973.1 - 0.0057 15.5 0.0 0.0057 15.5 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAM22973.1 - 0.027 14.4 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAM22973.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIOX PF05153.15 GAM22974.1 - 3.7e-119 396.8 5.7 4.3e-119 396.6 5.7 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 GAM22974.1 - 0.075 13.2 0.0 0.32 11.2 0.0 2.0 3 0 0 3 3 3 0 HD domain WD40 PF00400.32 GAM22975.1 - 9.6e-50 165.5 22.0 5.9e-09 36.4 0.1 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM22975.1 - 7.2e-26 90.3 2.7 1.6e-06 28.3 0.1 6.9 2 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM22975.1 - 9.5e-11 41.9 0.4 0.00034 20.6 0.1 3.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 GAM22975.1 - 1.5e-09 37.5 1.0 2.9e-09 36.6 1.0 1.5 1 0 0 1 1 1 1 LisH SpoIIP PF07454.11 GAM22975.1 - 0.00022 20.8 5.6 0.00036 20.1 5.6 1.3 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) WD40_like PF17005.5 GAM22975.1 - 0.0017 17.8 0.0 2.4 7.4 0.0 3.3 3 1 0 3 3 3 2 WD40-like domain Zip PF02535.22 GAM22975.1 - 0.033 13.4 3.0 0.043 13.0 3.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RAB3GAP2_N PF14655.6 GAM22975.1 - 0.042 13.1 0.0 0.96 8.6 0.0 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CSG2 PF16965.5 GAM22975.1 - 0.052 12.5 2.6 0.076 11.9 2.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator SLC12 PF03522.15 GAM22975.1 - 0.12 11.4 8.1 0.16 10.9 8.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 GAM22975.1 - 0.18 9.7 8.4 0.24 9.3 8.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPR3 PF03666.13 GAM22975.1 - 0.23 10.2 14.9 0.34 9.6 14.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 GAM22975.1 - 0.27 9.3 4.8 0.33 9.0 4.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec62 PF03839.16 GAM22975.1 - 0.36 10.3 14.2 0.55 9.7 14.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CDC45 PF02724.14 GAM22975.1 - 0.45 8.8 16.1 0.61 8.3 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 GAM22975.1 - 0.71 10.2 19.4 1.3 9.3 19.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PTPRCAP PF15713.5 GAM22975.1 - 0.84 9.9 10.1 1.5 9.1 10.1 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RPN2_C PF18004.1 GAM22975.1 - 0.99 9.3 18.9 2.1 8.3 18.9 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SAPS PF04499.15 GAM22975.1 - 2 7.1 11.1 2.6 6.7 11.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 GAM22975.1 - 3 6.5 11.2 4.3 6.0 11.2 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GAM22975.1 - 4 7.2 14.4 6 6.6 14.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 COQ9 PF08511.11 GAM22978.1 - 6.4e-31 106.0 1.1 1.2e-30 105.1 1.1 1.5 1 0 0 1 1 1 1 COQ9 Macoilin PF09726.9 GAM22978.1 - 0.16 10.5 2.9 0.17 10.4 2.9 1.1 1 0 0 1 1 1 0 Macoilin family KOG2701 PF09762.9 GAM22979.1 - 5.8e-63 212.3 0.0 5.8e-63 212.3 0.0 3.4 3 1 1 4 4 4 1 Coiled-coil domain-containing protein (DUF2037) UBA_2 PF08587.11 GAM22979.1 - 0.039 14.1 0.3 0.26 11.4 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) MAPKK1_Int PF08923.10 GAM22979.1 - 0.044 13.6 0.2 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Mitogen-activated protein kinase kinase 1 interacting ECH_2 PF16113.5 GAM22979.1 - 0.49 9.8 7.5 0.24 10.9 0.3 2.6 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase DUF1843 PF08898.10 GAM22979.1 - 1.7 9.2 5.9 1 9.9 1.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF2730 PF10805.8 GAM22979.1 - 2.7 8.1 6.8 6.8 6.8 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Ribosomal_L30 PF00327.20 GAM22980.1 - 8e-13 48.1 0.3 1.2e-12 47.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Gal11_ABD1 PF18535.1 GAM22980.1 - 0.07 13.2 0.6 6.8 6.9 0.0 2.5 2 1 1 3 3 3 0 Gal11 activator-binding domain (ABD1) VHS PF00790.19 GAM22981.1 - 1.5e-23 83.2 0.0 3.3e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 GAM22981.1 - 2.3e-12 47.0 3.8 3.2e-12 46.6 2.2 2.1 2 0 0 2 2 2 1 GAT domain RabGAP-TBC PF00566.18 GAM22982.1 - 7.4e-32 110.7 2.7 7.4e-32 110.7 2.7 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 GAM22983.1 - 9.8e-12 45.0 0.2 9.8e-12 45.0 0.2 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Tir_receptor_C PF07489.11 GAM22983.1 - 2.3 8.2 5.6 3.2 7.7 5.6 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus BCL_N PF04714.13 GAM22984.1 - 8e-07 29.0 0.6 2.1e-06 27.7 0.6 1.8 1 0 0 1 1 1 1 BCL7, N-terminal conserver region DUF3439 PF11921.8 GAM22984.1 - 0.52 10.3 6.4 0.37 10.8 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SAC3_GANP PF03399.16 GAM22985.1 - 1.6e-25 90.1 7.8 1.4e-23 83.8 7.8 2.6 1 1 0 1 1 1 1 SAC3/GANP family IMUP PF15761.5 GAM22985.1 - 3.5 8.4 10.2 0.11 13.1 1.5 2.9 3 0 0 3 3 3 0 Immortalisation up-regulated protein TIG PF01833.24 GAM22986.1 - 2e-63 210.5 151.0 9.7e-09 35.2 1.8 17.0 12 4 5 17 17 17 13 IPT/TIG domain EGF_2 PF07974.13 GAM22986.1 - 0.0021 18.4 11.2 0.0021 18.4 11.2 2.1 2 0 0 2 2 2 1 EGF-like domain EB PF01683.18 GAM22986.1 - 0.21 11.9 2.7 0.66 10.3 2.7 1.8 1 0 0 1 1 1 0 EB module EGF PF00008.27 GAM22986.1 - 1.3 9.4 11.1 2.7 8.4 8.2 2.7 2 0 0 2 2 2 0 EGF-like domain DHHC PF01529.20 GAM22987.1 - 1e-32 113.1 15.6 1e-32 113.1 15.6 2.8 2 2 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 GAM22987.1 - 7.6 6.7 7.9 16 5.7 7.9 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger CBS PF00571.28 GAM22989.1 - 2.2e-28 98.4 0.7 1.9e-11 44.2 0.0 4.2 4 0 0 4 4 4 4 CBS domain SGT1 PF07093.11 GAM22989.1 - 0.019 13.4 0.1 0.027 12.9 0.1 1.1 1 0 0 1 1 1 0 SGT1 protein RGS PF00615.19 GAM22990.1 - 2.4e-44 150.4 14.9 6e-17 62.0 0.2 5.1 5 1 1 6 6 6 3 Regulator of G protein signaling domain RGS-like PF09128.11 GAM22990.1 - 2.2e-12 47.1 7.3 1.2e-05 25.1 0.0 4.4 4 0 0 4 4 4 2 Regulator of G protein signalling-like domain THP2 PF09432.10 GAM22990.1 - 0.052 13.6 4.7 0.079 13.0 2.7 2.3 2 0 0 2 2 2 0 Tho complex subunit THP2 DUF1492 PF07374.11 GAM22990.1 - 0.24 11.6 2.3 0.62 10.3 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) DUF1002 PF06207.11 GAM22990.1 - 0.47 10.0 5.6 0.88 9.1 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) CH PF00307.31 GAM22991.1 - 9.7e-44 148.0 15.3 4.4e-13 49.4 0.2 5.9 5 0 0 5 5 5 5 Calponin homology (CH) domain PH PF00169.29 GAM22991.1 - 7.3e-16 58.6 0.4 6.3e-15 55.6 0.1 2.6 2 0 0 2 2 2 1 PH domain FERM_f0 PF16511.5 GAM22991.1 - 9.4e-13 48.3 0.3 1e-08 35.4 0.0 2.9 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM FERM_N PF09379.10 GAM22991.1 - 0.0014 18.5 0.2 0.14 12.1 0.1 3.1 2 0 0 2 2 2 1 FERM N-terminal domain Mcp5_PH PF12814.7 GAM22991.1 - 0.033 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.6 GAM22991.1 - 0.04 14.3 4.4 0.098 13.1 0.1 3.9 4 0 0 4 4 4 0 Pleckstrin homology domain CAMSAP_CH PF11971.8 GAM22991.1 - 0.053 13.4 0.0 0.79 9.6 0.0 3.0 3 0 0 3 3 3 0 CAMSAP CH domain SecY PF00344.20 GAM22992.1 - 1.8e-74 250.8 13.6 2.2e-74 250.5 13.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 GAM22992.1 - 3.2e-18 65.3 0.6 1e-17 63.7 0.1 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p QCR10 PF09796.9 GAM22992.1 - 4.5 7.4 6.5 3.5 7.8 0.1 3.6 4 0 0 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Usp PF00582.26 GAM22993.1 - 6e-05 23.6 2.4 0.00023 21.7 0.1 2.5 2 1 0 2 2 2 1 Universal stress protein family DUF733 PF05306.11 GAM22993.1 - 0.33 11.3 3.8 0.27 11.6 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF733) CBS PF00571.28 GAM22994.1 - 2.5e-18 66.2 4.9 1.4e-05 25.4 0.1 3.5 3 0 0 3 3 3 3 CBS domain G-alpha PF00503.20 GAM22995.1 - 1.1e-114 383.4 5.8 1.2e-114 383.2 5.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM22995.1 - 6.7e-14 51.7 0.4 7.2e-10 38.6 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM22995.1 - 0.0002 20.8 2.6 0.032 13.6 0.6 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM22995.1 - 0.0024 18.1 1.4 2 8.6 0.1 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAM22995.1 - 0.0078 16.3 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase NABP PF07990.12 GAM22995.1 - 0.089 12.3 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Cullin_binding PF03556.15 GAM22996.1 - 2.4e-28 99.0 0.6 3.5e-28 98.5 0.6 1.2 1 0 0 1 1 1 1 Cullin binding FNIP PF05725.12 GAM22997.1 - 5.9e-79 260.0 27.5 1.1e-11 44.6 0.1 12.3 7 1 6 14 14 14 13 FNIP Repeat Spc7 PF08317.11 GAM22997.1 - 0.0034 16.3 19.2 0.0051 15.7 19.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3552 PF12072.8 GAM22997.1 - 0.012 15.0 29.8 0.11 12.0 13.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF4349 PF14257.6 GAM22997.1 - 0.033 13.6 3.7 0.062 12.7 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Exonuc_VII_L PF02601.15 GAM22997.1 - 0.067 12.8 7.2 0.1 12.1 7.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MscS_porin PF12795.7 GAM22997.1 - 0.17 11.4 11.2 0.27 10.7 11.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain UPF0242 PF06785.11 GAM22997.1 - 6.7 6.8 19.3 11 6.1 19.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DDE_Tnp_4 PF13359.6 GAM22998.1 - 2.3e-23 82.6 0.4 1.2e-21 77.1 0.3 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM22998.1 - 2.7e-08 33.7 1.9 4.7e-08 32.9 1.9 1.4 1 1 0 1 1 1 1 Transposase DDE domain FNIP PF05725.12 GAM22999.1 - 6.8e-71 234.2 39.8 2.6e-13 49.9 0.6 10.5 5 3 7 13 13 13 13 FNIP Repeat DUF1769 PF08588.10 GAM22999.1 - 0.094 12.9 7.4 27 5.1 0.2 6.0 4 2 2 6 6 6 0 Protein of unknown function (DUF1769) DUF1741 PF08427.10 GAM23000.1 - 1.9e-62 211.0 2.1 4.1e-62 209.9 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) CHASE6_C PF17150.4 GAM23000.1 - 0.22 12.2 0.8 3.3 8.4 0.3 2.4 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain Spore_III_AB PF09548.10 GAM23001.1 - 0.18 11.9 0.0 0.18 11.9 0.0 1.0 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Aldo_ket_red PF00248.21 GAM23002.1 - 1.3e-44 152.5 0.0 7.5e-43 146.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family EGF PF00008.27 GAM23003.1 - 0.00023 21.4 11.3 0.00023 21.4 11.3 2.0 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 GAM23003.1 - 0.00024 21.4 11.3 0.00051 20.4 11.3 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 GAM23003.1 - 0.00086 19.8 7.0 0.0027 18.3 7.0 1.9 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_CA PF07645.15 GAM23003.1 - 0.98 9.7 8.7 0.97 9.7 6.4 2.1 2 0 0 2 2 2 0 Calcium-binding EGF domain Ribosomal_S13 PF00416.22 GAM23004.1 - 2e-51 173.7 5.1 2.3e-51 173.5 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 GAM23004.1 - 0.042 12.6 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Choline_transpo PF04515.12 GAM23005.1 - 1.8e-60 204.9 39.3 1.8e-60 204.9 39.3 2.3 1 1 1 2 2 2 1 Plasma-membrane choline transporter DUF4231 PF14015.6 GAM23005.1 - 0.054 14.0 0.2 0.054 14.0 0.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) DUF3399 PF11879.8 GAM23006.1 - 0.034 14.5 0.8 0.039 14.3 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) Coiled PF05710.12 GAM23006.1 - 0.034 15.0 5.4 0.041 14.7 5.1 1.3 1 1 0 1 1 1 0 Coiled coil Myosin_TH1 PF06017.13 GAM23007.1 - 5.8e-06 26.1 0.3 0.00023 20.9 0.3 2.2 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding RasGEF PF00617.19 GAM23008.1 - 6.6e-55 186.0 6.1 1.8e-54 184.6 1.5 3.1 3 0 0 3 3 3 1 RasGEF domain LRR_8 PF13855.6 GAM23008.1 - 4.4e-31 106.4 23.6 1.6e-09 37.4 2.8 7.0 4 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAM23008.1 - 7.6e-26 89.8 20.4 0.0004 20.7 0.0 8.3 4 2 3 7 7 7 6 Leucine Rich repeats (2 copies) RasGEF_N PF00618.20 GAM23008.1 - 3.1e-16 59.5 0.6 5.8e-14 52.2 0.1 3.4 2 0 0 2 2 2 1 RasGEF N-terminal motif Drf_GBD PF06371.13 GAM23008.1 - 6.5e-14 51.9 0.1 2.3e-13 50.1 0.1 1.9 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain FERM_f0 PF16511.5 GAM23008.1 - 4.8e-08 33.2 0.0 0.02 15.2 0.0 3.8 3 0 0 3 3 3 2 N-terminal or F0 domain of Talin-head FERM Drf_FH3 PF06367.16 GAM23008.1 - 1.2e-07 31.5 0.1 2.8e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 Diaphanous FH3 Domain FERM_N PF09379.10 GAM23008.1 - 0.015 15.2 0.2 1.2 9.1 0.0 3.3 2 1 0 2 2 2 0 FERM N-terminal domain LRR_1 PF00560.33 GAM23008.1 - 0.018 15.5 16.1 15 6.6 0.0 8.6 8 1 0 8 8 8 0 Leucine Rich Repeat dCMP_cyt_deam_1 PF00383.23 GAM23009.1 - 4.9e-23 80.9 1.7 7.3e-23 80.4 1.7 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAM23009.1 - 6.2e-22 77.8 2.9 2.2e-21 76.0 2.9 1.8 1 1 0 1 1 1 1 MafB19-like deaminase TTc_toxin_rep PF18807.1 GAM23009.1 - 0.027 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Tripartite Tc toxins repeat Inv-AAD PF18785.1 GAM23009.1 - 0.057 13.3 0.5 0.12 12.2 0.5 1.7 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase Bd3614-deam PF14439.6 GAM23009.1 - 0.72 9.9 10.4 0.23 11.5 4.5 2.7 2 1 0 2 2 2 0 Bd3614-like deaminase Hemerythrin PF01814.23 GAM23010.1 - 6e-15 56.0 1.9 5.4e-11 43.2 1.0 1.7 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain DUF1186 PF06685.11 GAM23010.1 - 0.0044 16.4 0.5 0.0074 15.7 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1186) TcdB_N PF12918.7 GAM23010.1 - 0.013 15.8 1.8 0.064 13.5 0.1 2.3 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Occludin_ELL PF07303.13 GAM23010.1 - 0.018 15.7 1.6 4.3 8.1 0.1 2.2 2 0 0 2 2 2 0 Occludin homology domain Pro-kuma_activ PF09286.11 GAM23014.1 - 2e-26 93.0 0.4 2.5e-26 92.7 0.4 1.1 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF1980 PF09323.10 GAM23014.1 - 0.056 13.3 0.4 0.085 12.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2140 PF09911.9 GAM23014.1 - 0.089 12.3 1.2 0.17 11.4 0.4 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Peptidase_C11 PF03415.14 GAM23015.1 - 0.00065 19.2 0.5 0.2 11.1 0.0 2.0 2 0 0 2 2 2 2 Clostripain family FNIP PF05725.12 GAM23016.1 - 7.7e-32 109.2 13.3 1.5e-08 34.7 0.8 5.0 5 0 0 5 5 5 4 FNIP Repeat Glyco_hydro_65C PF03633.15 GAM23016.1 - 0.019 14.9 0.1 29 4.7 0.0 4.4 5 0 0 5 5 5 0 Glycosyl hydrolase family 65, C-terminal domain FNIP PF05725.12 GAM23017.1 - 2.8e-44 149.0 26.3 1.6e-11 44.2 1.7 4.6 1 1 5 6 6 6 6 FNIP Repeat Glyco_hydro_65C PF03633.15 GAM23017.1 - 0.034 14.1 0.0 14 5.7 0.0 4.0 4 0 0 4 4 4 0 Glycosyl hydrolase family 65, C-terminal domain SCF PF02404.15 GAM23017.1 - 0.059 12.7 0.2 0.14 11.4 0.1 1.6 2 0 0 2 2 2 0 Stem cell factor FNIP PF05725.12 GAM23019.1 - 7.5e-30 102.8 22.6 3.7e-09 36.6 0.4 5.3 1 1 6 7 7 7 7 FNIP Repeat tRNA-synt_1 PF00133.22 GAM23020.1 - 1.2e-209 697.5 0.7 1.2e-209 697.5 0.7 2.7 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM23020.1 - 7.6e-40 136.4 0.2 7.6e-40 136.4 0.2 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM23020.1 - 2.4e-14 52.9 0.3 7.2e-07 28.3 0.1 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAM23020.1 - 1.1e-06 28.3 0.0 1.1e-06 28.3 0.0 3.2 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAM23020.1 - 0.09 12.1 5.7 0.24 10.7 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain SOBP PF15279.6 GAM23020.1 - 6.7 7.2 7.9 11 6.5 7.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PGI PF00342.19 GAM23021.1 - 9e-237 786.4 0.0 1e-236 786.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase SOR_SNZ PF01680.17 GAM23022.1 - 1.3e-110 368.0 5.9 2.3e-110 367.2 5.9 1.4 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 GAM23022.1 - 7.1e-07 28.8 0.9 7.1e-07 28.8 0.9 2.7 3 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG IGPS PF00218.21 GAM23022.1 - 0.0012 18.1 1.2 0.89 8.7 0.0 3.2 3 1 0 3 3 3 2 Indole-3-glycerol phosphate synthase NanE PF04131.14 GAM23022.1 - 0.0031 16.7 1.9 0.16 11.1 0.0 3.0 2 1 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.17 GAM23022.1 - 0.0054 15.9 3.2 0.33 10.0 0.1 2.8 3 1 0 3 3 3 2 Dihydrouridine synthase (Dus) OMPdecase PF00215.24 GAM23022.1 - 0.02 14.5 0.0 2 8.0 0.0 2.5 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TetR_C_27 PF17935.1 GAM23022.1 - 0.025 14.6 0.1 0.071 13.2 0.0 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Lsm_C PF14894.6 GAM23022.1 - 0.98 9.2 5.3 16 5.3 0.1 3.8 3 1 1 4 4 4 0 Lsm C-terminal SNO PF01174.19 GAM23023.1 - 1.7e-40 138.9 0.1 2.1e-40 138.6 0.1 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 GAM23023.1 - 3.7e-08 33.2 0.0 5.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 GAM23023.1 - 0.013 15.3 0.1 0.045 13.5 0.1 1.8 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 GAM23023.1 - 0.03 14.0 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 Ribosomal_L11_N PF03946.14 GAM23024.1 - 1.6e-18 66.3 0.5 2.7e-18 65.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 GAM23024.1 - 1.7e-16 60.5 0.2 3.2e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Oleosin PF01277.17 GAM23025.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Oleosin zf-UBR PF02207.20 GAM23026.1 - 1.6e-17 63.4 13.1 1.6e-17 63.4 13.1 3.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 GAM23026.1 - 1.6e-05 24.6 0.2 4.5e-05 23.1 0.2 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 GAM23026.1 - 0.013 15.9 0.2 0.013 15.9 0.2 3.8 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4 PF00097.25 GAM23026.1 - 0.019 14.8 0.3 0.019 14.8 0.3 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Amidohydro_3 PF07969.11 GAM23027.1 - 2e-18 67.1 0.9 4.3e-11 42.9 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 GAM23027.1 - 4.3e-18 65.7 0.3 8.1e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family SHOCT PF09851.9 GAM23027.1 - 0.1 12.3 0.0 0.61 9.9 0.0 2.3 2 0 0 2 2 2 0 Short C-terminal domain DUF4213 PF13938.6 GAM23027.1 - 5.4 7.3 5.5 22 5.4 0.2 3.5 3 1 0 3 3 3 0 Putative heavy-metal chelation DEAD PF00270.29 GAM23028.1 - 1.4e-22 80.3 0.0 2.9e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM23028.1 - 5.3e-16 58.9 0.0 1.1e-13 51.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GAM23028.1 - 1.4e-10 41.7 2.5 1.9e-10 41.3 0.6 2.3 2 0 0 2 2 2 1 RecQ zinc-binding Adenine_glyco PF03352.13 GAM23028.1 - 0.062 13.1 0.5 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Methyladenine glycosylase MaoC_dehydratas PF01575.19 GAM23029.1 - 2e-24 85.5 0.0 2.8e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GAM23029.1 - 2.4e-05 24.5 0.0 3.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase JAB PF01398.21 GAM23030.1 - 8.2e-21 74.2 0.0 8.2e-21 74.2 0.0 4.1 3 1 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 GAM23030.1 - 4.8e-17 62.2 1.4 4.8e-17 62.2 1.4 3.4 3 1 1 4 4 4 1 USP8 dimerisation domain Prok-JAB PF14464.6 GAM23030.1 - 1.8e-05 24.5 0.9 8.3e-05 22.3 0.0 2.7 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain E3_UFM1_ligase PF09743.9 GAM23031.1 - 8e-100 333.9 9.8 8e-100 333.9 9.8 2.3 3 0 0 3 3 3 1 E3 UFM1-protein ligase 1 FeoC PF09012.10 GAM23031.1 - 0.074 13.1 0.0 0.48 10.5 0.0 2.5 2 0 0 2 2 2 0 FeoC like transcriptional regulator UPF0061 PF02696.14 GAM23031.1 - 0.54 9.0 6.6 0.36 9.6 3.8 2.0 1 1 1 2 2 2 0 Uncharacterized ACR, YdiU/UPF0061 family zf-UBR PF02207.20 GAM23032.1 - 9.6e-11 41.7 7.5 9.6e-11 41.7 7.5 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) PrmA PF06325.13 GAM23032.1 - 0.14 11.5 0.7 0.31 10.4 0.7 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2283 PF10049.9 GAM23033.1 - 0.0018 18.5 0.3 0.0028 17.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2283) ProQ_C PF17516.2 GAM23033.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 ProQ C-terminal domain HEAT PF02985.22 GAM23034.1 - 2e-44 145.8 18.8 0.00015 21.7 0.0 14.0 15 0 0 15 15 15 11 HEAT repeat HEAT_2 PF13646.6 GAM23034.1 - 1.1e-36 125.0 0.0 3.4e-09 37.0 0.0 7.3 2 1 4 7 7 7 7 HEAT repeats Adaptin_N PF01602.20 GAM23034.1 - 1.2e-11 43.9 8.9 0.0017 17.0 0.5 4.6 2 1 2 4 4 4 4 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 GAM23034.1 - 4.7e-09 36.7 0.3 0.19 12.3 0.0 6.5 4 2 3 7 7 7 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 GAM23034.1 - 8.8e-09 35.3 0.6 0.025 14.1 0.0 4.4 2 1 2 4 4 4 2 CLASP N terminal Cnd1 PF12717.7 GAM23034.1 - 3.4e-08 33.7 8.0 0.0013 18.8 0.7 5.3 2 1 4 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAM23034.1 - 4e-07 30.4 6.4 0.17 12.5 0.0 7.4 6 2 2 8 8 8 2 HEAT-like repeat RTP1_C1 PF10363.9 GAM23034.1 - 6.8e-06 26.2 2.0 1.6 9.0 0.1 4.4 4 1 1 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 GAM23034.1 - 0.0023 17.9 1.3 29 4.9 0.0 5.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat IFRD PF05004.13 GAM23034.1 - 0.045 12.9 6.0 0.35 9.9 0.2 4.0 3 2 2 5 5 5 0 Interferon-related developmental regulator (IFRD) tRNA-synt_His PF13393.6 GAM23034.1 - 0.14 11.4 2.0 0.58 9.4 0.3 2.4 3 0 0 3 3 3 0 Histidyl-tRNA synthetase UCR_UQCRX_QCR9 PF05365.12 GAM23035.1 - 3.3e-22 78.2 0.7 4.1e-22 77.9 0.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Pkinase PF00069.25 GAM23036.1 - 2.2e-64 217.4 0.3 1.5e-63 214.6 0.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM23036.1 - 6.2e-29 101.1 1.6 3.2e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 GAM23036.1 - 8.6e-05 23.2 0.2 0.00022 21.8 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 GAM23036.1 - 0.00021 21.3 0.2 0.11 12.4 0.4 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM23036.1 - 0.0024 16.9 0.3 0.0048 15.9 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain DUF3987 PF13148.6 GAM23036.1 - 0.0077 15.3 0.7 0.054 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) Seadorna_VP7 PF07387.11 GAM23036.1 - 0.0085 15.2 0.3 0.018 14.1 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Kinase-like PF14531.6 GAM23036.1 - 0.022 14.1 0.0 0.54 9.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like GRIP PF01465.20 GAM23037.1 - 9e-13 47.9 0.4 2.6e-12 46.5 0.4 1.9 1 0 0 1 1 1 1 GRIP domain Rab_bind PF16704.5 GAM23037.1 - 0.00068 19.6 5.6 0.00068 19.6 5.6 3.8 3 0 0 3 3 3 1 Rab binding domain SNARE PF05739.19 GAM23037.1 - 0.48 10.5 2.6 2 8.5 0.5 3.2 2 0 0 2 2 2 0 SNARE domain Ant_C PF05586.11 GAM23037.1 - 0.86 10.2 0.0 0.86 10.2 0.0 4.4 4 1 1 5 5 5 0 Anthrax receptor C-terminus region ADH_zinc_N_2 PF13602.6 GAM23038.1 - 1.4e-17 65.0 0.0 2.9e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM23038.1 - 1.9e-08 34.1 0.0 2.9e-07 30.3 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAM23038.1 - 3.1e-08 33.7 0.0 5.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NUC130_3NT PF08158.12 GAM23038.1 - 0.041 14.2 0.0 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 NUC130/3NT domain DapB_N PF01113.20 GAM23038.1 - 0.11 12.6 0.2 0.45 10.7 0.2 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 GAM23038.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SAM_1 PF00536.30 GAM23040.1 - 0.0031 17.9 0.0 0.0069 16.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM23040.1 - 0.0051 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FAM176 PF14851.6 GAM23040.1 - 0.065 12.9 0.9 0.13 11.9 0.9 1.4 1 0 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 GAM23040.1 - 0.069 12.7 3.8 0.13 11.8 3.8 1.4 1 0 0 1 1 1 0 PPP4R2 HasA PF06438.12 GAM23040.1 - 0.07 12.8 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Heme-binding protein A (HasA) Med13_C PF06333.12 GAM23040.1 - 0.1 11.9 0.6 0.15 11.3 0.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain SWIB PF02201.18 GAM23040.1 - 0.1 12.5 0.6 2.2 8.3 0.0 2.8 3 0 0 3 3 3 0 SWIB/MDM2 domain Cwf_Cwc_15 PF04889.12 GAM23040.1 - 0.14 11.8 6.2 0.23 11.1 6.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4609 PF15382.6 GAM23040.1 - 0.16 11.8 0.1 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) CENP-B_dimeris PF09026.10 GAM23040.1 - 0.66 10.4 14.3 1.6 9.2 14.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 GAM23040.1 - 5.4 6.8 7.4 12 5.7 7.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region ILEI PF15711.5 GAM23041.1 - 1.2e-22 80.2 0.3 1.6e-14 54.1 0.0 3.2 3 0 0 3 3 3 3 Interleukin-like EMT inducer DUF3767 PF12597.8 GAM23043.1 - 1.5e-12 47.2 0.0 2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Rpr2 PF04032.16 GAM23044.1 - 0.24 11.7 16.1 17 5.8 0.4 3.6 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_L37ae PF01780.19 GAM23044.1 - 0.32 11.1 15.0 0.15 12.2 0.8 2.6 3 0 0 3 3 3 0 Ribosomal L37ae protein family zf-C2HC5 PF06221.13 GAM23044.1 - 0.65 10.0 6.9 0.24 11.4 2.1 2.2 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type OrfB_Zn_ribbon PF07282.11 GAM23044.1 - 1.4 8.9 14.5 3 7.8 4.3 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain FYVE PF01363.21 GAM23044.1 - 2.5 8.3 15.7 4.3 7.5 6.4 2.7 1 1 1 2 2 2 0 FYVE zinc finger DUF1451 PF07295.11 GAM23044.1 - 6.7 6.7 7.7 8.6 6.4 1.5 2.4 2 0 0 2 2 2 0 Zinc-ribbon containing domain CBS PF00571.28 GAM23045.1 - 7.3e-28 96.8 0.3 6.7e-15 55.3 0.2 2.5 2 0 0 2 2 2 2 CBS domain FNIP PF05725.12 GAM23046.1 - 5.5e-14 52.1 2.6 2.7e-05 24.2 0.0 6.3 5 1 0 5 5 5 4 FNIP Repeat F-box_5 PF18511.1 GAM23046.1 - 1.5e-07 30.9 0.4 4e-07 29.5 0.2 1.9 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 GAM23046.1 - 0.0015 18.4 0.9 0.0033 17.3 0.1 2.0 2 0 0 2 2 2 1 F-box-like ADP_ribosyl_GH PF03747.14 GAM23047.1 - 1.8e-40 139.5 0.0 2.1e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase PaREP1 PF05942.11 GAM23047.1 - 0.046 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family DDE_Tnp_4 PF13359.6 GAM23049.1 - 2.3e-23 82.6 0.4 1.2e-21 77.1 0.3 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM23049.1 - 2.7e-08 33.7 1.9 4.7e-08 32.9 1.9 1.4 1 1 0 1 1 1 1 Transposase DDE domain ADP_ribosyl_GH PF03747.14 GAM23050.1 - 6.7e-15 55.6 0.0 8.1e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Pigment_DH PF06324.11 GAM23050.1 - 0.076 13.1 0.5 0.23 11.6 0.5 1.8 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) Kelch_6 PF13964.6 GAM23051.1 - 1.1e-12 47.7 9.5 5.3e-06 26.5 0.0 4.9 4 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAM23051.1 - 1.3e-08 34.7 22.1 5.1e-06 26.4 0.0 6.8 6 2 1 7 7 7 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM23051.1 - 4.1e-08 32.7 8.9 0.00031 20.3 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 GAM23051.1 - 4.8e-05 23.2 3.0 0.004 17.1 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 GAM23051.1 - 0.00029 21.1 2.5 15 6.1 0.0 5.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Baculo_PEP_C PF04513.12 GAM23051.1 - 0.042 13.9 0.2 0.092 12.8 0.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 GAM23051.1 - 0.062 13.3 1.8 0.17 11.9 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Kelch_5 PF13854.6 GAM23051.1 - 0.76 9.8 11.3 1.4 9.0 0.1 4.0 4 0 0 4 4 4 0 Kelch motif zf-B_box PF00643.24 GAM23051.1 - 2.5 8.3 16.8 0.081 13.1 8.6 2.5 2 0 0 2 2 2 0 B-box zinc finger SANT_DAMP1_like PF16282.5 GAM23052.1 - 2.9e-28 97.9 4.8 2.9e-28 97.9 4.8 2.0 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 GAM23052.1 - 0.0056 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DMAP1 PF05499.12 GAM23052.1 - 0.0097 15.8 0.5 0.0097 15.8 0.5 4.5 2 2 1 4 4 4 1 DNA methyltransferase 1-associated protein 1 (DMAP1) RNA_lig_T4_1 PF09511.10 GAM23053.1 - 2.1e-37 129.1 0.2 6.9e-37 127.4 0.0 1.9 2 0 0 2 2 2 1 RNA ligase PA14 PF07691.12 GAM23054.1 - 4.3e-10 39.6 0.8 9.1e-10 38.5 0.8 1.5 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 GAM23054.1 - 2.4e-09 36.9 45.4 3.2e-06 26.9 6.8 13.8 13 3 0 13 13 13 7 Dictyostelium (slime mold) repeat Amidohydro_3 PF07969.11 GAM23055.1 - 2.7 7.3 8.7 2.9 7.3 7.2 1.7 1 1 0 1 1 1 0 Amidohydrolase family MAD PF05557.13 GAM23055.1 - 7.9 4.7 121.6 2.7 6.2 42.4 4.2 1 1 3 4 4 4 0 Mitotic checkpoint protein Acetyltransf_1 PF00583.25 GAM23056.1 - 4.4e-14 52.7 0.1 5.8e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM23056.1 - 1.8e-10 41.1 0.2 2.8e-10 40.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM23056.1 - 3.6e-08 33.4 0.1 4.8e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_C39 PF03412.15 GAM23056.1 - 0.028 14.2 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 Peptidase C39 family Cys_rich_CPXG PF14255.6 GAM23056.1 - 0.062 13.2 2.2 8.6 6.3 0.3 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG Acetyltransf_3 PF13302.7 GAM23056.1 - 0.078 13.7 0.0 0.11 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Epimerase PF01370.21 GAM23057.1 - 1.7e-21 76.8 0.1 2.7e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM23057.1 - 1.9e-11 43.5 0.5 1.5e-10 40.6 0.5 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAM23057.1 - 4.8e-11 42.9 0.0 9.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAM23057.1 - 4.6e-10 39.4 0.0 7.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAM23057.1 - 1.2e-05 24.5 0.1 2.2e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DnaB PF00772.21 GAM23057.1 - 0.0024 17.9 0.1 0.043 13.9 0.0 2.3 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain NAD_binding_4 PF07993.12 GAM23057.1 - 0.033 13.4 0.8 0.37 9.9 0.8 2.4 1 1 0 1 1 1 0 Male sterility protein KR PF08659.10 GAM23057.1 - 0.039 13.9 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF1731 PF08338.11 GAM23057.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) PX PF00787.24 GAM23058.1 - 1.6e-19 70.0 0.9 2.1e-19 69.6 0.9 1.2 1 0 0 1 1 1 1 PX domain PQ-loop PF04193.14 GAM23059.1 - 5.3e-08 32.5 21.4 0.00085 19.0 5.8 2.5 2 0 0 2 2 2 2 PQ loop repeat Otopetrin PF03189.13 GAM23059.1 - 5.3e-06 25.5 0.1 4.3e-05 22.5 0.0 1.9 1 1 1 2 2 2 1 Otopetrin PGA2 PF07543.12 GAM23059.1 - 0.17 11.9 0.1 0.17 11.9 0.1 2.7 2 1 0 2 2 1 0 Protein trafficking PGA2 Zip PF02535.22 GAM23059.1 - 0.25 10.5 14.2 2.4 7.3 0.1 3.1 1 1 1 2 2 2 0 ZIP Zinc transporter V_ATPase_I PF01496.19 GAM23059.1 - 0.42 8.5 11.7 23 2.7 0.0 3.0 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 GAM23059.1 - 0.48 9.1 0.0 0.48 9.1 0.0 2.9 3 0 0 3 3 3 0 Presenilin SpoIIIAH PF12685.7 GAM23059.1 - 1.6 8.5 31.1 0.36 10.6 0.2 3.3 2 1 1 3 3 3 0 SpoIIIAH-like protein DUF4551 PF15087.6 GAM23059.1 - 2.6 6.8 17.4 0.29 9.9 8.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Neur_chan_memb PF02932.16 GAM23059.1 - 2.9 7.9 10.6 9.2 6.3 5.5 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 GAM23059.1 - 3.5 7.3 18.7 12 5.6 8.2 3.7 2 2 0 2 2 2 0 Connexin BUD22 PF09073.10 GAM23059.1 - 6 6.1 40.1 0.14 11.5 20.6 2.0 2 0 0 2 2 2 0 BUD22 Methyltransf_23 PF13489.6 GAM23060.1 - 4.3e-16 59.2 0.0 5.2e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM23060.1 - 5.7e-16 58.7 0.0 6.9e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM23060.1 - 3.9e-14 53.1 0.0 5.5e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM23060.1 - 7.3e-13 49.1 0.0 1.1e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM23060.1 - 7.9e-13 48.9 0.0 1.2e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM23060.1 - 4.1e-08 32.8 0.0 5.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAM23060.1 - 3e-05 23.6 0.0 6.7e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 GAM23060.1 - 0.097 12.3 0.0 0.29 10.7 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW NNMT_PNMT_TEMT PF01234.17 GAM23060.1 - 0.1 11.8 0.0 0.29 10.3 0.0 1.6 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_2 PF00891.18 GAM23060.1 - 0.12 11.7 0.0 0.4 9.9 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain Gelsolin PF00626.22 GAM23062.1 - 6.1e-33 112.6 0.0 7e-11 41.9 0.1 4.1 4 0 0 4 4 4 3 Gelsolin repeat VHP PF02209.19 GAM23062.1 - 2.7e-12 46.5 2.5 5.8e-12 45.5 2.5 1.6 1 0 0 1 1 1 1 Villin headpiece domain DUF1921 PF09081.10 GAM23062.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) STI1 PF17830.1 GAM23062.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 STI1 domain PEPCK_GTP PF00821.18 GAM23063.1 - 1.2e-175 583.6 0.1 1.5e-175 583.2 0.1 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 GAM23063.1 - 1.5e-102 341.8 0.0 1.9e-102 341.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain TPR_2 PF07719.17 GAM23064.1 - 1.2e-12 46.9 15.2 0.2 11.8 0.0 9.8 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAM23064.1 - 2.3e-10 39.8 11.2 0.0091 15.8 0.1 8.4 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM23064.1 - 1.1e-09 38.2 9.8 27 5.9 0.0 9.1 4 1 5 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM23064.1 - 1.2e-09 38.6 18.6 0.0033 17.9 0.1 8.2 8 1 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM23064.1 - 4.8e-08 32.6 10.9 0.046 13.9 0.0 7.9 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM23064.1 - 1.8e-07 31.3 13.7 1.8 8.9 0.1 7.1 5 3 2 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM23064.1 - 7.2e-07 28.8 8.9 0.19 11.4 0.1 5.7 6 1 1 7 7 7 3 TPR repeat ANAPC3 PF12895.7 GAM23064.1 - 2.9e-05 24.2 15.2 0.072 13.3 0.2 5.7 3 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GAM23064.1 - 7.2e-05 22.1 5.3 0.012 14.8 0.1 5.0 2 1 2 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM23064.1 - 0.00019 21.5 0.2 0.0036 17.4 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM23064.1 - 0.0023 18.0 0.4 1.7 8.8 0.0 3.6 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 GAM23064.1 - 0.0032 18.1 1.9 54 4.6 0.0 5.9 6 2 1 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM23064.1 - 0.0033 17.4 5.3 65 3.9 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM23064.1 - 0.025 15.2 6.2 1.1e+02 3.7 0.3 7.2 9 0 0 9 9 7 0 Tetratricopeptide repeat Porin_3 PF01459.22 GAM23065.1 - 1.6e-12 47.5 0.5 2.3e-12 47.0 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic porin MDM10 PF12519.8 GAM23065.1 - 1e-08 34.5 2.2 5.4e-08 32.1 2.1 2.0 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Candida_ALS_N PF11766.8 GAM23065.1 - 0.011 15.0 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding PGM_PMM_I PF02878.16 GAM23066.1 - 1.4e-35 122.0 0.4 2.2e-35 121.3 0.4 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GAM23066.1 - 1.3e-27 96.3 0.0 2.3e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAM23066.1 - 5.2e-13 49.5 0.0 1.2e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 GAM23066.1 - 1.7e-05 24.9 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SH3_9 PF14604.6 GAM23067.1 - 1.5e-21 76.0 1.0 2.6e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAM23067.1 - 3.8e-21 74.4 0.5 5e-15 54.8 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 GAM23067.1 - 3.5e-18 65.0 0.3 1.4e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 GAM23067.1 - 2.1e-10 40.7 0.8 6e-10 39.3 0.1 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 GAM23067.1 - 0.58 9.5 9.3 0.87 8.9 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Beach PF02138.18 GAM23068.1 - 5.7e-120 399.9 0.5 5.7e-120 399.9 0.5 2.5 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 GAM23068.1 - 2.6e-14 53.1 4.3 4.4e-14 52.4 0.0 2.8 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 GAM23068.1 - 7.1e-09 36.2 19.7 0.0041 17.9 1.3 7.0 6 1 0 6 6 6 3 WD domain, G-beta repeat Mucin PF01456.17 GAM23068.1 - 0.0011 19.0 2.2 0.0011 19.0 2.2 4.8 7 0 0 7 7 7 1 Mucin-like glycoprotein TFIIA PF03153.13 GAM23068.1 - 0.0026 17.8 19.2 0.0026 17.8 19.2 6.1 6 1 0 6 6 6 1 Transcription factor IIA, alpha/beta subunit WD40_like PF17005.5 GAM23068.1 - 0.0051 16.2 0.0 0.07 12.4 0.0 2.4 2 0 0 2 2 2 1 WD40-like domain PepSY_TM PF03929.16 GAM23068.1 - 0.024 14.3 7.1 0.49 10.0 0.0 2.6 2 0 0 2 2 2 0 PepSY-associated TM region NPH3 PF03000.14 GAM23068.1 - 0.16 11.5 13.2 0.0057 16.3 4.1 3.1 3 0 0 3 3 3 0 NPH3 family DUF3419 PF11899.8 GAM23069.1 - 8.3e-18 64.7 0.0 1.8e-17 63.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 GAM23069.1 - 0.003 18.2 0.0 0.19 12.4 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM23069.1 - 0.0048 17.6 0.0 1.3 9.8 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain AAA_assoc_C PF09821.9 GAM23069.1 - 0.042 14.4 0.6 11 6.6 0.0 2.7 2 1 0 2 2 2 0 C-terminal AAA-associated domain Methyltransf_11 PF08241.12 GAM23069.1 - 0.13 12.9 0.0 0.57 10.9 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain DUF1084 PF06454.11 GAM23070.1 - 1.1e-17 64.3 19.7 2e-16 60.2 19.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Ank_2 PF12796.7 GAM23072.1 - 6.7e-39 132.4 32.4 2.8e-09 37.4 0.3 6.9 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM23072.1 - 2.8e-38 129.5 23.9 0.0044 17.3 0.1 14.8 3 2 12 15 15 15 11 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM23072.1 - 5.1e-38 129.0 17.0 7.1e-06 26.5 0.0 10.4 5 4 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM23072.1 - 1e-17 62.4 10.4 5 8.0 0.0 13.7 14 2 2 16 16 16 3 Ankyrin repeat Ank PF00023.30 GAM23072.1 - 1.2e-07 31.8 7.9 25 5.6 0.1 10.3 4 4 4 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 GAM23072.1 - 1.4e-06 28.1 11.4 6 6.8 0.0 10.6 5 5 9 14 14 14 1 Domain of unknown function (DUF5049) AhpC-TSA PF00578.21 GAM23072.1 - 0.00029 20.8 0.0 12 5.8 0.0 4.8 4 2 1 5 5 5 2 AhpC/TSA family PyrI PF01948.18 GAM23072.1 - 0.049 13.9 0.2 4.1 7.7 0.0 3.8 3 2 3 6 6 6 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain Bunya_G2 PF03563.13 GAM23072.1 - 0.53 9.5 3.1 6.8 5.9 0.0 3.8 3 1 1 5 5 5 0 Bunyavirus glycoprotein G2 BRCT_2 PF16589.5 GAM23073.1 - 1.1e-09 38.6 0.1 2.3e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAM23073.1 - 4.4e-08 33.4 0.2 9.1e-08 32.4 0.2 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 GAM23073.1 - 0.0016 18.7 0.6 0.0094 16.2 0.4 2.3 2 1 0 2 2 2 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 GAM23073.1 - 0.0022 17.9 0.3 0.0042 17.0 0.3 1.5 1 0 0 1 1 1 1 twin BRCT domain Mitoc_L55 PF09776.9 GAM23073.1 - 0.048 13.4 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Peptidase_M28 PF04389.17 GAM23074.1 - 1.5e-10 41.1 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 GAM23074.1 - 2.6e-08 33.6 0.0 5.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Nicastrin Pex2_Pex12 PF04757.14 GAM23075.1 - 1.3e-58 198.2 11.1 1.6e-58 198.0 11.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 GAM23075.1 - 0.00013 21.8 2.4 0.0002 21.2 2.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM23075.1 - 0.0034 17.2 4.8 0.0056 16.5 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM23075.1 - 0.023 15.0 4.8 0.039 14.3 4.8 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 GAM23075.1 - 0.098 12.5 4.0 0.17 11.7 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM23075.1 - 0.36 10.9 9.0 0.79 9.8 9.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAM23075.1 - 0.64 10.2 7.0 1.1 9.4 7.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF5089 PF17002.5 GAM23076.1 - 0.065 13.1 5.9 0.13 12.1 5.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) FERM_f0 PF16511.5 GAM23077.1 - 1.8e-25 89.1 3.7 1.2e-15 57.6 0.0 4.6 5 0 0 5 5 5 3 N-terminal or F0 domain of Talin-head FERM RhoGAP PF00620.27 GAM23077.1 - 9.6e-16 58.0 0.4 9.6e-15 54.7 0.1 2.3 2 0 0 2 2 2 1 RhoGAP domain Ank_2 PF12796.7 GAM23078.1 - 1.9e-09 38.0 2.3 1e-05 26.0 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM23078.1 - 3.7e-07 30.6 2.9 0.015 15.9 0.1 4.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM23078.1 - 4e-07 29.8 1.5 5.6 7.9 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAM23078.1 - 2.2e-06 27.8 3.0 0.045 14.1 0.0 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Viral_helicase1 PF01443.18 GAM23078.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cullin_Nedd8 PF10557.9 GAM23079.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.7 1 1 1 2 2 2 0 Cullin protein neddylation domain DUF4660 PF15559.6 GAM23080.1 - 0.029 14.7 0.3 0.064 13.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) CSN8_PSD8_EIF3K PF10075.9 GAM23082.1 - 0.057 13.4 0.9 0.085 12.8 0.9 1.3 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Coiled PF05710.12 GAM23083.1 - 0.00062 20.5 11.7 0.00077 20.2 11.7 1.1 1 0 0 1 1 1 1 Coiled coil WH1 PF00568.23 GAM23084.1 - 1.6e-21 76.3 0.1 2.4e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 GAM23084.1 - 5.1e-18 65.2 0.1 1.3e-17 63.9 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 GAM23084.1 - 1.5e-07 31.0 0.6 3.2e-07 29.9 0.6 1.5 1 0 0 1 1 1 1 WH2 motif DCP1 PF06058.13 GAM23084.1 - 0.0073 16.2 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family DUF3484 PF11983.8 GAM23084.1 - 0.011 16.8 0.9 0.022 15.9 0.9 1.5 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Ribosomal_60s PF00428.19 GAM23084.1 - 0.02 15.5 6.1 0.02 15.5 6.1 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF1084 PF06454.11 GAM23085.1 - 6.7e-05 22.4 25.5 0.0031 16.9 25.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) 7tm_1 PF00001.21 GAM23085.1 - 0.015 14.6 15.8 0.021 14.2 15.8 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF368 PF04018.13 GAM23085.1 - 0.95 9.0 14.6 0.097 12.2 6.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF368) Siva PF05458.12 GAM23086.1 - 0.28 10.9 29.5 0.27 10.9 28.6 1.8 1 1 0 1 1 1 0 Cd27 binding protein (Siva) SMC_hinge PF06470.13 GAM23086.1 - 2.9 8.2 5.1 14 6.1 5.0 1.9 1 1 0 1 1 1 0 SMC proteins Flexible Hinge Domain Menin PF05053.13 GAM23086.1 - 6.3 5.0 11.3 7.4 4.8 11.3 1.1 1 0 0 1 1 1 0 Menin zf-ZPR1 PF03367.13 GAM23087.1 - 1.4e-109 363.0 0.0 1.4e-54 184.2 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 GAM23087.1 - 0.0015 18.5 0.5 0.29 11.2 0.0 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HAGH_C PF16123.5 GAM23087.1 - 0.052 14.1 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus DUF1912 PF08930.10 GAM23087.1 - 0.099 12.8 0.7 7.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) zf-Mss51 PF13824.6 GAM23087.1 - 0.28 11.3 2.4 7.9 6.7 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_RNApol_7kD PF03604.13 GAM23087.1 - 7.2 6.4 9.8 61 3.4 0.1 4.1 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit RasGEF PF00617.19 GAM23088.1 - 2.8e-54 184.0 1.7 1.1e-53 182.0 1.7 2.2 1 0 0 1 1 1 1 RasGEF domain LRR_8 PF13855.6 GAM23088.1 - 8.6e-28 95.9 48.8 1.1e-09 37.8 0.6 7.0 2 1 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 GAM23088.1 - 7.3e-25 86.6 30.5 2.1e-05 24.8 0.2 8.7 4 2 6 10 10 10 9 Leucine Rich repeats (2 copies) Drf_GBD PF06371.13 GAM23088.1 - 4.3e-17 62.3 0.4 1.2e-16 60.9 0.4 1.8 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain RasGEF_N PF00618.20 GAM23088.1 - 3.5e-13 49.7 1.3 2.2e-12 47.2 0.6 2.8 1 1 1 2 2 2 1 RasGEF N-terminal motif Drf_FH3 PF06367.16 GAM23088.1 - 1.5e-08 34.5 0.0 4.3e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain LRR_6 PF13516.6 GAM23088.1 - 0.0073 16.3 17.0 1.9 8.8 0.1 7.6 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.33 GAM23088.1 - 0.0088 16.5 17.3 7.6 7.5 0.1 8.7 8 1 0 8 8 8 1 Leucine Rich Repeat HSP20 PF00011.21 GAM23089.1 - 1.9e-11 44.0 9.0 1.4e-07 31.6 0.1 3.3 2 1 1 4 4 4 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM23089.1 - 0.0033 16.9 0.0 0.051 13.1 0.0 2.3 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Patched PF02460.18 GAM23089.1 - 0.0095 14.1 7.2 0.01 14.0 7.2 1.1 1 0 0 1 1 1 1 Patched family DUF3523 PF12037.8 GAM23089.1 - 9.7 5.5 48.4 2.5 7.4 44.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) DUF4347 PF14252.6 GAM23090.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) PI3K_rbd PF00794.18 GAM23092.1 - 3.9e-10 39.9 0.0 7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain RBD PF02196.15 GAM23092.1 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain RA PF00788.23 GAM23092.1 - 0.096 13.3 0.3 0.22 12.2 0.0 1.8 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain FNIP PF05725.12 GAM23093.1 - 2.8e-56 187.4 40.4 4.4e-13 49.2 2.9 8.8 4 3 3 9 9 9 8 FNIP Repeat DUF1769 PF08588.10 GAM23093.1 - 0.0051 17.0 2.6 9.2 6.6 0.3 4.8 4 2 1 5 5 5 2 Protein of unknown function (DUF1769) Pap_E4 PF02711.14 GAM23094.1 - 0.013 16.4 4.2 0.013 16.4 4.2 2.0 2 0 0 2 2 2 0 E4 protein DUF3446 PF11928.8 GAM23094.1 - 0.5 10.7 14.7 0.071 13.4 9.1 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF5470 PF17564.2 GAM23094.1 - 1.1 9.5 5.6 0.44 10.8 1.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5470) Ephrin_rec_like PF07699.13 GAM23095.1 - 7.8e-14 51.2 61.1 9.9e-08 31.6 7.2 6.9 1 1 8 9 9 9 9 Putative ephrin-receptor like VSP PF03302.13 GAM23095.1 - 0.00033 19.6 43.5 0.00049 19.1 14.8 2.8 1 1 2 3 3 3 2 Giardia variant-specific surface protein NCD3G PF07562.14 GAM23095.1 - 0.0047 16.9 54.3 0.025 14.5 4.6 6.1 4 1 3 7 7 7 5 Nine Cysteines Domain of family 3 GPCR RNA_pol_Rpb4 PF03874.16 GAM23096.1 - 5.5e-21 75.2 0.5 8.3e-21 74.6 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 rve PF00665.26 GAM23099.1 - 3.7e-10 40.0 0.0 6.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Peptidase_C48 PF02902.19 GAM23101.1 - 3.1e-08 33.7 0.0 9.2e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Mucin PF01456.17 GAM23101.1 - 0.01 15.8 19.6 0.02 14.9 19.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RBB1NT PF08169.11 GAM23101.1 - 0.051 13.7 0.1 0.16 12.2 0.1 1.9 1 0 0 1 1 1 0 RBB1NT (NUC162) domain Totivirus_coat PF05518.11 GAM23101.1 - 1.3 7.0 7.2 1.8 6.5 7.2 1.2 1 0 0 1 1 1 0 Totivirus coat protein WRC PF08879.10 GAM23102.1 - 0.073 12.8 7.9 0.068 12.9 3.8 2.6 1 1 1 2 2 2 0 WRC DUF1936 PF09151.10 GAM23102.1 - 1.6 8.7 5.0 3.7 7.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) AAA_16 PF13191.6 GAM23105.1 - 0.019 15.4 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAM23105.1 - 0.029 14.6 0.0 0.2 12.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain HTH_Mga PF08280.11 GAM23105.1 - 0.12 12.4 0.2 9.4 6.4 0.0 3.0 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Mito_carr PF00153.27 GAM23106.1 - 0.034 14.1 0.1 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial carrier protein DnaJ PF00226.31 GAM23106.1 - 0.066 13.4 0.5 0.25 11.5 0.5 2.0 1 1 0 1 1 1 0 DnaJ domain DUF2569 PF10754.9 GAM23106.1 - 0.56 10.6 6.1 4.6 7.7 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DnaJ PF00226.31 GAM23107.1 - 1.6e-07 31.3 1.6 6.9e-07 29.3 1.6 2.0 1 1 0 1 1 1 1 DnaJ domain RPT PF13446.6 GAM23107.1 - 0.0012 18.7 0.3 0.0026 17.7 0.3 1.5 1 0 0 1 1 1 1 A repeated domain in UCH-protein Mito_carr PF00153.27 GAM23107.1 - 0.0028 17.5 0.3 0.27 11.2 0.0 2.8 2 1 0 2 2 2 1 Mitochondrial carrier protein ABC2_membrane PF01061.24 GAM23108.1 - 1.6e-32 112.6 15.9 2.8e-32 111.9 15.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAM23108.1 - 2.9e-25 89.4 0.0 4.5e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM23108.1 - 5.9e-05 23.0 0.1 0.051 13.4 0.3 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM23108.1 - 0.00036 20.2 0.1 0.00088 19.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 GAM23108.1 - 0.00045 20.0 0.0 0.00072 19.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM23108.1 - 0.0025 18.4 0.0 0.0044 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM23108.1 - 0.0053 17.1 0.0 0.0088 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 GAM23108.1 - 0.0065 15.9 0.0 0.12 11.8 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAM23108.1 - 0.0076 16.2 0.5 0.016 15.1 0.2 1.6 2 0 0 2 2 1 1 RsgA GTPase AAA_25 PF13481.6 GAM23108.1 - 0.01 15.4 0.2 0.018 14.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM23108.1 - 0.089 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 GAM23108.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_22 PF13401.6 GAM23108.1 - 0.14 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAM23108.1 - 0.15 12.5 0.3 0.37 11.3 0.1 1.7 1 1 1 2 2 2 0 AAA domain Myosin_TH1 PF06017.13 GAM23109.1 - 1.5e-07 31.3 0.2 0.00019 21.2 0.2 2.2 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding Carm_PH PF17888.1 GAM23109.1 - 0.0065 16.8 0.1 0.017 15.5 0.1 1.6 1 0 0 1 1 1 1 Carmil pleckstrin homology domain SMN PF06003.12 GAM23110.1 - 2.6e-06 26.9 13.1 2.6e-06 26.9 13.1 2.9 1 1 2 3 3 3 1 Survival motor neuron protein (SMN) RTT107_BRCT_5 PF16770.5 GAM23110.1 - 1.8 8.5 6.1 0.33 10.9 1.7 2.0 1 1 1 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF3439 PF11921.8 GAM23110.1 - 3.6 7.6 10.6 0.21 11.6 4.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Miga PF10265.9 GAM23110.1 - 3.7 6.4 9.1 5 6.0 9.1 1.2 1 0 0 1 1 1 0 Mitoguardin Ribosomal_S13 PF00416.22 GAM23111.1 - 2e-51 173.7 5.1 2.3e-51 173.5 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 GAM23111.1 - 0.042 12.6 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4369 PF14289.6 GAM23112.1 - 0.055 14.0 0.1 0.055 14.0 0.1 4.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4369) DUF748 PF05359.11 GAM23112.1 - 0.1 12.7 13.6 0.18 12.0 0.5 5.0 3 2 1 4 4 4 0 Domain of Unknown Function (DUF748) SecY PF00344.20 GAM23114.1 - 1.8e-74 250.8 13.6 2.2e-74 250.5 13.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 GAM23114.1 - 3.2e-18 65.3 0.6 1e-17 63.7 0.1 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p QCR10 PF09796.9 GAM23114.1 - 4.5 7.4 6.5 3.5 7.8 0.1 3.6 4 0 0 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) GST_C PF00043.25 GAM23115.1 - 2.9e-14 53.1 0.0 5.4e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM23115.1 - 4.9e-12 46.0 0.0 1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM23115.1 - 8.6e-11 41.7 0.2 2.6e-09 36.9 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM23115.1 - 3.7e-09 36.7 0.0 7.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM23115.1 - 5.2e-08 33.2 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM23115.1 - 2.2e-07 31.1 0.0 4.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAM23115.1 - 0.11 12.4 0.0 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ribosomal_L17 PF01196.19 GAM23116.1 - 1.6e-30 105.8 1.2 2.3e-30 105.3 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 CBS PF00571.28 GAM23117.1 - 3e-22 78.8 0.8 7.9e-08 32.6 0.1 3.3 3 0 0 3 3 3 3 CBS domain Peptidase_A3 PF02160.15 GAM23117.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 1 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) zf-B_box PF00643.24 GAM23118.1 - 5.2e-05 23.3 8.3 9.4e-05 22.5 8.3 1.4 1 0 0 1 1 1 1 B-box zinc finger RIG-I_C-RD PF11648.8 GAM23118.1 - 1 9.6 6.5 1.7 8.9 1.5 2.3 2 0 0 2 2 2 0 C-terminal domain of RIG-I Acyl_transf_3 PF01757.22 GAM23119.1 - 1.9e-26 93.0 43.9 3e-26 92.3 43.9 1.3 1 0 0 1 1 1 1 Acyltransferase family SET PF00856.28 GAM23121.1 - 0.053 13.9 0.0 0.069 13.5 0.0 1.3 1 0 0 1 1 1 0 SET domain Peptidase_C48 PF02902.19 GAM23122.1 - 0.079 12.8 0.4 2.9 7.7 0.1 2.3 2 0 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain PROL5-SMR PF15621.6 GAM23122.1 - 4.9 7.7 15.0 0.17 12.4 5.3 2.8 1 1 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Dimer_Tnp_hAT PF05699.14 GAM23123.1 - 2.5e-12 46.4 0.0 7.4e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Chon_Sulph_att PF06566.11 GAM23124.1 - 0.035 14.0 0.4 0.059 13.2 0.4 1.4 1 1 0 1 1 1 0 Chondroitin sulphate attachment domain Thioredoxin_6 PF13848.6 GAM23124.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain LANC_like PF05147.13 GAM23125.1 - 1.6e-58 198.0 0.7 2e-58 197.7 0.7 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein zf-C3HC4_3 PF13920.6 GAM23126.1 - 1.5e-09 37.6 10.6 2.1e-09 37.1 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM23126.1 - 4.1e-07 30.2 14.5 6.4e-07 29.6 14.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM23126.1 - 4.3e-06 26.5 13.8 8.8e-06 25.5 13.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM23126.1 - 5.2e-06 26.4 12.8 0.00011 22.2 7.4 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 GAM23126.1 - 2.4e-05 24.2 11.7 7e-05 22.7 11.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAM23126.1 - 3.4e-05 23.6 11.6 0.00034 20.4 12.2 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM23126.1 - 4.2e-05 23.3 11.9 8e-05 22.4 11.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAM23126.1 - 0.0043 17.2 10.7 0.1 12.8 11.7 2.5 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAM23126.1 - 0.0053 16.6 6.2 0.0097 15.8 6.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GAM23126.1 - 0.013 15.7 13.3 0.073 13.4 13.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Baculo_p48 PF04878.13 GAM23126.1 - 0.023 13.7 1.3 0.027 13.4 1.3 1.2 1 0 0 1 1 1 0 Baculovirus P48 protein zf-HIT PF04438.16 GAM23126.1 - 0.028 14.3 7.7 0.22 11.4 2.2 2.2 2 0 0 2 2 2 0 HIT zinc finger DUF2371 PF10177.9 GAM23126.1 - 0.086 13.0 1.2 0.12 12.6 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) UPF0542 PF15086.6 GAM23126.1 - 0.23 11.4 1.8 0.46 10.4 1.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 FYVE PF01363.21 GAM23126.1 - 0.25 11.5 13.6 1.3 9.2 8.2 2.8 1 1 1 2 2 2 0 FYVE zinc finger zf-RING_4 PF14570.6 GAM23126.1 - 0.27 11.1 10.2 0.56 10.0 10.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 GAM23126.1 - 1.6 8.5 13.9 6.2 6.7 10.1 2.7 2 1 0 2 2 2 0 RING-like zinc finger RecR PF02132.15 GAM23126.1 - 7.2 6.3 13.6 4.5 6.9 1.4 3.0 1 1 1 2 2 2 0 RecR protein DNA_repr_REX1B PF14966.6 GAM23127.1 - 1.7e-26 92.7 4.3 2.3e-25 89.1 1.0 2.1 2 0 0 2 2 2 2 DNA repair REX1-B DUF4407 PF14362.6 GAM23127.1 - 0.77 9.1 3.9 0.69 9.2 2.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DASH_Dad3 PF08656.10 GAM23127.1 - 0.78 9.9 6.1 8.7 6.5 6.1 2.5 1 1 0 1 1 1 0 DASH complex subunit Dad3 UPF0139 PF03669.13 GAM23128.1 - 1.2e-28 98.8 0.0 1.3e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Dpy19 PF10034.9 GAM23128.1 - 0.018 13.3 0.1 0.019 13.2 0.1 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation LisH PF08513.11 GAM23129.1 - 0.00014 21.7 0.9 0.00014 21.7 0.9 2.0 2 0 0 2 2 2 1 LisH Arm_3 PF16186.5 GAM23130.1 - 3.1e-14 52.3 0.5 5.7e-14 51.4 0.5 1.4 1 0 0 1 1 1 1 Atypical Arm repeat Arm PF00514.23 GAM23130.1 - 2.7e-06 27.2 0.2 5.3e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat SIL1 PF16782.5 GAM23130.1 - 0.0028 16.9 0.0 0.003 16.8 0.0 1.0 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 MYEOV2 PF15004.6 GAM23130.1 - 0.0094 16.4 0.5 0.12 12.8 0.2 2.1 2 0 0 2 2 2 1 Myeloma-overexpressed-like V-ATPase_H_C PF11698.8 GAM23130.1 - 0.065 13.4 0.1 0.14 12.3 0.1 1.5 1 1 0 1 1 1 0 V-ATPase subunit H Arm PF00514.23 GAM23131.1 - 7.1e-09 35.4 0.1 0.00051 20.0 0.0 2.1 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat YniB PF14002.6 GAM23132.1 - 0.018 14.8 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 YniB-like protein IBB PF01749.20 GAM23133.1 - 1.4e-13 51.0 1.2 1.9e-13 50.6 1.2 1.2 1 0 0 1 1 1 1 Importin beta binding domain DUF1564 PF07600.11 GAM23133.1 - 0.0075 16.0 0.2 0.011 15.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1564) Peptidase_S46 PF10459.9 GAM23133.1 - 0.38 9.4 2.7 0.41 9.2 2.7 1.0 1 0 0 1 1 1 0 Peptidase S46 SdrD_B PF17210.3 GAM23134.1 - 2.6e-15 56.6 14.3 5e-06 26.7 0.2 8.6 5 2 2 8 8 8 5 SdrD B-like domain DUF1933 PF09147.10 GAM23134.1 - 0.00018 21.2 1.1 9.9 5.7 0.0 5.3 6 1 1 7 7 7 2 Domain of unknown function (DUF1933) zf-4CXXC_R1 PF10497.9 GAM23135.1 - 5.3e-10 39.4 15.6 5.3e-10 39.4 15.6 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PWWP PF00855.17 GAM23135.1 - 2.2e-06 27.9 0.0 2.2e-06 27.9 0.0 2.9 3 0 0 3 3 3 1 PWWP domain JmjC PF02373.22 GAM23135.1 - 2.6e-05 24.6 1.2 0.00023 21.5 0.0 3.1 3 0 0 3 3 3 1 JmjC domain, hydroxylase PA26 PF04636.13 GAM23135.1 - 0.95 8.3 7.2 0.74 8.7 0.2 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Spem1 PF15670.5 GAM23135.1 - 3.5 7.1 11.9 1.9 8.0 1.0 3.0 2 0 0 2 2 2 0 Spermatid maturation protein 1 Menin PF05053.13 GAM23135.1 - 7.4 4.8 24.5 0.27 9.5 14.1 2.2 2 0 0 2 2 2 0 Menin Hydrolase PF00702.26 GAM23136.1 - 7.5e-41 140.7 0.0 1.3e-40 139.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAM23136.1 - 5.3e-40 136.9 1.1 5.3e-40 136.9 1.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAM23136.1 - 1.6e-06 28.1 0.2 6.6e-05 22.8 0.6 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAM23136.1 - 2.9e-06 27.6 0.8 0.0014 19.0 0.1 3.2 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.7 GAM23136.1 - 0.00035 21.0 0.0 0.0014 19.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3487 PF11990.8 GAM23136.1 - 6.5 6.7 7.4 2.3 8.1 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3487) Pkinase PF00069.25 GAM23138.1 - 3.3e-63 213.5 0.0 6.6e-63 212.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM23138.1 - 4.2e-43 147.5 0.0 6.7e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM23138.1 - 0.00076 18.9 0.1 0.0022 17.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAM23138.1 - 0.00094 18.1 0.0 0.00094 18.1 0.0 3.0 2 1 0 3 3 3 1 Fungal protein kinase APH PF01636.23 GAM23138.1 - 0.0036 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM23138.1 - 0.016 14.2 0.4 0.016 14.2 0.4 2.5 2 1 0 2 2 2 0 Haspin like kinase domain UCR_TM PF02921.14 GAM23138.1 - 0.3 11.6 0.1 0.3 11.6 0.1 2.5 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region DUF4307 PF14155.6 GAM23139.1 - 0.077 12.8 2.5 0.12 12.2 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) UAA PF08449.11 GAM23140.1 - 1.3e-38 133.0 27.7 2.1e-38 132.3 27.7 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAM23140.1 - 3e-07 30.7 14.2 3e-07 30.7 14.2 2.9 3 0 0 3 3 3 2 EamA-like transporter family FA_hydroxylase PF04116.13 GAM23140.1 - 9.5 6.6 9.0 1.7 9.0 0.1 3.1 3 1 0 4 4 4 0 Fatty acid hydroxylase superfamily Glyco_hydro_9 PF00759.19 GAM23141.1 - 2.3e-126 422.6 9.8 2.7e-126 422.3 9.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM49 PF09478.10 GAM23141.1 - 3.4e-15 56.1 0.1 6.4e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 PT PF04886.12 GAM23141.1 - 1.5e-05 24.4 53.8 3.1e-05 23.4 26.6 2.3 1 1 1 2 2 2 2 PT repeat DUF4106 PF13388.6 GAM23141.1 - 0.027 13.7 11.1 0.042 13.1 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) FAM75 PF14650.6 GAM23141.1 - 8.8 5.8 12.5 13 5.2 12.5 1.1 1 0 0 1 1 1 0 FAM75 family CBM49 PF09478.10 GAM23142.1 - 2.1e-11 44.0 1.3 2.1e-11 44.0 1.3 2.5 1 1 2 3 3 3 1 Carbohydrate binding domain CBM49 SPX PF03105.19 GAM23142.1 - 0.029 14.3 9.1 0.028 14.4 9.1 1.0 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 GAM23142.1 - 0.6 8.6 13.2 0.62 8.6 13.2 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 GAM23142.1 - 0.71 8.6 10.2 0.81 8.4 10.2 1.1 1 0 0 1 1 1 0 Presenilin MAP65_ASE1 PF03999.12 GAM23142.1 - 6 5.4 11.5 5.8 5.5 11.5 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF1387 PF07139.11 GAM23142.1 - 8.5 6.0 13.5 10 5.7 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Glyco_hydro_9 PF00759.19 GAM23143.1 - 1.1e-95 321.5 1.5 1.3e-95 321.3 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 FNIP PF05725.12 GAM23144.1 - 9.6e-89 291.3 21.0 6.6e-16 58.2 0.3 8.0 4 1 7 12 12 12 10 FNIP Repeat Ras PF00071.22 GAM23145.1 - 2e-59 199.8 0.0 2.4e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM23145.1 - 9e-21 74.3 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM23145.1 - 1.7e-09 37.4 0.0 2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM23145.1 - 2.9e-06 27.0 0.3 2.5e-05 23.9 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM23145.1 - 0.00011 22.3 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM23145.1 - 0.00011 22.1 0.2 0.51 10.2 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase ATP_bind_1 PF03029.17 GAM23145.1 - 0.012 15.4 0.8 0.14 11.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 GAM23145.1 - 0.033 13.5 0.0 0.07 12.4 0.0 1.6 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 GAM23145.1 - 0.045 13.3 0.1 0.26 10.8 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B ParA PF10609.9 GAM23145.1 - 0.2 11.1 0.4 0.78 9.1 0.1 1.9 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase RhoGEF PF00621.20 GAM23146.1 - 1.8e-44 152.2 10.0 2.9e-42 145.0 0.7 3.1 3 0 0 3 3 3 2 RhoGEF domain SUIM_assoc PF16619.5 GAM23146.1 - 0.00073 19.6 8.3 0.00073 19.6 8.3 3.2 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 IQ PF00612.27 GAM23146.1 - 0.0013 18.4 1.0 0.0027 17.4 1.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif SURF6 PF04935.12 GAM23146.1 - 0.5 10.1 14.5 0.084 12.7 9.6 2.1 2 0 0 2 2 2 0 Surfeit locus protein 6 PNISR PF15996.5 GAM23146.1 - 3.5 7.9 18.1 0.14 12.4 8.5 2.4 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR ANAPC_CDC26 PF10471.9 GAM23146.1 - 5.2 8.0 20.9 0.22 12.4 10.1 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Epimerase PF01370.21 GAM23147.1 - 1.5e-09 37.7 0.3 1.6e-07 31.1 0.3 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM23147.1 - 3.3e-07 30.4 0.0 5.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM23147.1 - 7.8e-07 28.9 2.0 0.00019 21.0 0.2 2.2 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.25 GAM23147.1 - 7.8e-05 22.2 0.2 0.00019 21.0 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 GAM23147.1 - 0.0001 21.9 0.0 0.0021 17.5 0.0 2.4 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 GAM23147.1 - 0.00011 22.1 4.5 0.004 17.1 2.2 2.5 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAM23147.1 - 0.00016 21.7 0.5 0.00037 20.6 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAM23147.1 - 0.00022 21.5 0.8 0.0063 16.8 0.1 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 GAM23147.1 - 0.00042 20.5 0.2 0.001 19.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 GAM23147.1 - 0.01 15.0 0.1 0.017 14.2 0.1 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAM23147.1 - 0.013 14.6 0.1 0.06 12.5 0.1 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AlaDh_PNT_C PF01262.21 GAM23147.1 - 0.018 14.3 2.4 0.023 14.0 0.1 2.2 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 GAM23147.1 - 0.03 14.6 0.4 0.03 14.6 0.4 1.7 2 0 0 2 2 2 0 TrkA-N domain DFP PF04127.15 GAM23147.1 - 0.032 14.1 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DapB_N PF01113.20 GAM23147.1 - 0.075 13.1 0.1 0.17 12.0 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PS_Dcarbxylase PF02666.15 GAM23148.1 - 8.5e-61 205.0 0.0 1e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase AIRS_C PF02769.22 GAM23149.1 - 1.1e-23 84.1 0.0 1.6e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 GAM23149.1 - 6.5e-08 33.1 0.0 1.3e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain LolA_like PF17131.4 GAM23150.1 - 1.3 8.8 2.4 1.5 8.5 2.4 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein ELYS PF13934.6 GAM23151.1 - 4.9e-25 88.8 3.2 1.3e-24 87.4 3.2 1.6 1 0 0 1 1 1 1 Nuclear pore complex assembly ELYS-bb PF16687.5 GAM23151.1 - 9.8e-20 70.6 1.4 3e-15 55.8 0.2 2.3 2 0 0 2 2 2 2 beta-propeller of ELYS nucleoporin PIP5K PF01504.18 GAM23152.1 - 5.9e-65 219.2 0.3 1.7e-64 217.7 0.3 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Orthopox_F7 PF05813.12 GAM23152.1 - 0.15 12.2 0.1 0.38 10.9 0.1 1.7 1 0 0 1 1 1 0 Orthopoxvirus F7 protein dDENN PF03455.19 GAM23152.1 - 4.5 7.3 11.4 0.26 11.3 0.8 3.4 3 0 0 3 3 3 0 dDENN domain Reticulon PF02453.17 GAM23153.1 - 4.3e-29 101.5 11.3 4.3e-29 101.5 11.3 1.8 2 0 0 2 2 2 1 Reticulon Apolipoprotein PF01442.18 GAM23153.1 - 8.3e-05 22.5 4.4 0.00015 21.7 4.4 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GAM23153.1 - 0.001 19.6 7.9 0.0031 18.0 7.8 1.9 1 0 0 1 1 1 1 YtxH-like protein DUF2884 PF11101.8 GAM23153.1 - 0.0019 17.8 0.6 0.094 12.2 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2884) REF PF05755.12 GAM23153.1 - 0.0073 16.1 1.5 0.0073 16.1 1.5 2.0 1 1 2 3 3 3 1 Rubber elongation factor protein (REF) phiKZ_IP PF12699.7 GAM23153.1 - 0.035 13.2 0.2 0.035 13.2 0.2 1.4 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins DUF883 PF05957.13 GAM23153.1 - 0.056 14.0 3.3 0.13 12.9 3.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Sec8_exocyst PF04048.14 GAM23153.1 - 0.067 13.1 1.2 0.13 12.1 1.2 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain ApoLp-III PF07464.11 GAM23153.1 - 0.11 12.6 10.1 0.074 13.1 8.1 1.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) MT0933_antitox PF14013.6 GAM23153.1 - 0.15 12.3 8.2 3.3 8.1 3.6 2.5 2 0 0 2 2 2 0 MT0933-like antitoxin protein APG17 PF04108.12 GAM23153.1 - 0.16 11.0 2.9 0.14 11.3 1.2 1.6 2 0 0 2 2 2 0 Autophagy protein Apg17 Sec5 PF15469.6 GAM23153.1 - 0.19 11.5 1.9 0.5 10.1 0.6 2.0 2 0 0 2 2 2 0 Exocyst complex component Sec5 MgtE PF01769.16 GAM23153.1 - 2.3 8.6 8.8 0.19 12.1 1.9 2.1 2 0 0 2 2 2 0 Divalent cation transporter Phasin PF05597.11 GAM23153.1 - 2.5 8.1 7.8 5.4 7.0 7.8 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.12 GAM23153.1 - 6.7 6.8 8.4 6.7 6.8 6.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_S5 PF00333.20 GAM23154.1 - 3.2e-17 62.3 2.2 5.9e-17 61.4 2.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain ATAD4 PF15321.6 GAM23154.1 - 0.69 11.3 0.1 0.69 11.3 0.1 2.5 2 1 1 3 3 3 0 ATPase family AAA domain containing 4 PLA2_B PF01735.18 GAM23155.1 - 0.046 12.1 0.1 0.046 12.1 0.1 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Presenilin PF01080.17 GAM23156.1 - 0.39 9.4 5.6 0.67 8.6 5.4 1.6 1 1 0 1 1 1 0 Presenilin PI3K_1B_p101 PF10486.9 GAM23157.1 - 0.28 8.9 1.1 0.31 8.8 1.1 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Amnionless PF14828.6 GAM23157.1 - 0.53 9.0 2.7 0.62 8.8 2.7 1.0 1 0 0 1 1 1 0 Amnionless TUDOR PF00567.24 GAM23158.1 - 5.2e-09 36.2 0.1 3.3e-08 33.6 0.0 2.3 3 0 0 3 3 3 1 Tudor domain SMN PF06003.12 GAM23158.1 - 2.5e-06 26.9 3.9 2.5e-06 26.9 3.9 2.2 1 1 2 3 3 3 1 Survival motor neuron protein (SMN) Agenet PF05641.12 GAM23158.1 - 0.00019 21.8 0.1 0.00047 20.6 0.1 1.7 1 0 0 1 1 1 1 Agenet domain DUF2730 PF10805.8 GAM23158.1 - 0.039 14.0 1.5 0.039 14.0 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) RskA PF10099.9 GAM23158.1 - 0.053 13.8 3.1 0.034 14.4 1.4 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA AAA_23 PF13476.6 GAM23158.1 - 0.18 12.3 14.8 0.84 10.1 1.6 2.3 2 0 0 2 2 2 0 AAA domain Ribosomal_S17_N PF16205.5 GAM23158.1 - 0.59 10.5 3.5 1.2 9.5 3.5 1.5 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal Meiotic_rec114 PF03525.14 GAM23158.1 - 0.91 8.4 11.6 1.8 7.5 11.6 1.4 1 1 0 1 1 1 0 Meiotic recombination protein rec114 IFT20 PF14931.6 GAM23158.1 - 1 9.6 9.6 0.096 12.9 2.2 2.2 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Allexi_40kDa PF05549.11 GAM23158.1 - 6.3 6.2 14.4 0.37 10.3 5.4 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein HAD_2 PF13419.6 GAM23159.1 - 1.9e-12 47.7 0.1 2.4e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM23159.1 - 1e-07 32.5 0.0 1.6e-05 25.3 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM23159.1 - 4.1e-05 23.6 0.0 6.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 GAM23159.1 - 0.051 13.4 0.0 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Acid Phosphatase Ras PF00071.22 GAM23160.1 - 1.7e-60 203.3 0.1 2e-60 203.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM23160.1 - 5.3e-34 117.0 0.0 7.2e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM23160.1 - 2.7e-15 56.3 0.0 3.4e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAM23160.1 - 2.1e-05 24.5 0.1 0.093 12.6 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GAM23160.1 - 0.00022 20.6 0.1 0.00027 20.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM23160.1 - 0.0011 19.0 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM23160.1 - 0.0043 16.6 0.1 0.024 14.2 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAM23160.1 - 0.023 14.1 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GAM23160.1 - 0.024 14.2 0.0 0.12 11.9 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 GAM23160.1 - 0.055 13.9 0.0 0.07 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 GAM23160.1 - 0.073 12.5 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 GAM23160.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM23160.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 GAM23160.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 GAM23160.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_transf_41 PF13844.6 GAM23161.1 - 2.1e-53 181.4 0.6 7.1e-28 97.3 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_20 PF14561.6 GAM23161.1 - 0.017 15.4 0.2 3.2 8.2 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat ZZ PF00569.17 GAM23162.1 - 1.5e-12 47.1 4.9 2.4e-12 46.5 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 GAM23162.1 - 1.7e-10 40.9 0.1 3.7e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM23162.1 - 3.7e-05 23.9 0.4 0.00018 21.7 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain C1_2 PF03107.16 GAM23162.1 - 0.034 14.5 2.8 0.07 13.5 2.8 1.5 1 0 0 1 1 1 0 C1 domain RNA_polI_A34 PF08208.11 GAM23162.1 - 0.085 12.9 20.8 0.24 11.5 1.8 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 OrsD PF12013.8 GAM23162.1 - 0.17 12.3 0.1 0.17 12.3 0.1 2.9 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF3446 PF11928.8 GAM23162.1 - 0.36 11.2 24.9 0.27 11.6 16.9 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Romo1 PF10247.9 GAM23163.1 - 9.4e-16 57.9 12.0 1.2e-15 57.6 12.0 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 PRIMA1 PF16101.5 GAM23163.1 - 0.086 12.9 0.8 0.11 12.6 0.8 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GAM23163.1 - 0.93 8.9 4.0 1.1 8.7 4.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ABC_membrane PF00664.23 GAM23164.1 - 2.9e-51 174.7 27.7 2.9e-51 174.7 27.7 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region Peptidase_S8 PF00082.22 GAM23164.1 - 1.3e-48 165.8 4.2 9.7e-48 162.9 3.2 2.4 2 0 0 2 2 2 1 Subtilase family ABC_tran PF00005.27 GAM23164.1 - 5.7e-32 111.1 0.4 1.6e-31 109.6 0.0 2.0 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 GAM23164.1 - 6.7e-07 29.0 5.2 5.2e-05 22.8 7.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM23164.1 - 0.001 19.0 2.4 0.56 10.0 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAM23164.1 - 0.0049 17.1 0.1 0.018 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain ECR1_N PF14382.6 GAM23164.1 - 0.0058 16.4 0.2 0.025 14.4 0.1 2.1 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region Protocadherin PF08374.11 GAM23164.1 - 0.0064 16.5 3.6 0.19 11.7 0.0 2.9 2 0 0 2 2 2 1 Protocadherin AAA_29 PF13555.6 GAM23164.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 GAM23164.1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 GAM23164.1 - 0.067 13.1 0.2 1.1 9.2 0.0 2.7 3 0 0 3 3 3 0 NTPase AAA_15 PF13175.6 GAM23164.1 - 0.096 12.4 0.1 0.096 12.4 0.1 2.7 2 1 0 2 2 1 0 AAA ATPase domain AAA_16 PF13191.6 GAM23164.1 - 0.19 12.1 0.0 0.58 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain TMEM154 PF15102.6 GAM23164.1 - 0.4 10.6 2.8 0.98 9.3 0.0 2.7 2 0 0 2 2 2 0 TMEM154 protein family CDC45 PF02724.14 GAM23164.1 - 4.9 5.3 15.1 8.9 4.5 15.1 1.3 1 0 0 1 1 1 0 CDC45-like protein RSN1_7TM PF02714.15 GAM23165.1 - 6.5e-68 229.0 24.5 6.5e-68 229.0 24.5 2.4 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAM23165.1 - 1.7e-37 128.5 4.9 1.7e-37 128.5 4.9 3.7 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAM23165.1 - 6.5e-20 72.1 0.0 9.3e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF3439 PF11921.8 GAM23166.1 - 0.34 10.9 5.2 0.81 9.7 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Nucleoside_tran PF01733.18 GAM23167.1 - 1.3e-32 113.4 23.4 2.1e-32 112.7 16.1 2.8 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 GAM23167.1 - 2.1e-06 26.9 33.1 4.6e-05 22.5 8.1 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily YfhO PF09586.10 GAM23167.1 - 0.29 9.3 22.6 0.29 9.3 7.2 2.2 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF3611 PF12263.8 GAM23167.1 - 3 7.7 12.1 0.053 13.4 1.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) RhoGAP PF00620.27 GAM23168.1 - 2.9e-36 124.6 0.1 6.2e-36 123.5 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain Reg_prop PF07494.11 GAM23168.1 - 0.0056 16.7 1.6 18 6.0 0.0 5.2 5 0 0 5 5 5 1 Two component regulator propeller Zip PF02535.22 GAM23168.1 - 0.25 10.5 4.0 0.4 9.9 4.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.12 GAM23168.1 - 0.55 9.6 17.1 0.96 8.8 17.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Raftlin PF15250.6 GAM23168.1 - 1.6 7.4 11.9 2.4 6.8 11.9 1.3 1 0 0 1 1 1 0 Raftlin DUF2052 PF09747.9 GAM23168.1 - 1.8 8.6 13.3 3.1 7.9 13.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF572 PF04502.13 GAM23168.1 - 2.6 7.6 22.4 4.2 6.9 22.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Menin PF05053.13 GAM23168.1 - 3.6 5.8 11.5 6.2 5.1 11.5 1.3 1 0 0 1 1 1 0 Menin Tim54 PF11711.8 GAM23168.1 - 3.8 6.2 11.7 7 5.3 11.7 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.15 GAM23168.1 - 5.9 5.6 12.0 9.5 4.9 12.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EAP30 PF04157.16 GAM23169.1 - 5.5e-72 241.9 0.9 6.2e-72 241.7 0.9 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Activator-TraM PF11657.8 GAM23169.1 - 0.11 12.4 0.9 0.24 11.2 0.9 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM zf-B_box PF00643.24 GAM23170.1 - 2.8e-09 37.0 6.8 5.6e-09 36.0 6.8 1.5 1 0 0 1 1 1 1 B-box zinc finger MtlR PF05068.12 GAM23170.1 - 0.013 15.5 0.2 0.026 14.5 0.2 1.5 1 0 0 1 1 1 0 Mannitol repressor DUF515 PF04415.12 GAM23170.1 - 0.34 9.2 3.5 0.51 8.7 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Kelch_6 PF13964.6 GAM23170.1 - 3.5 8.1 6.3 14 6.1 0.1 3.4 4 0 0 4 4 4 0 Kelch motif IBR PF01485.21 GAM23170.1 - 4.7 7.5 8.1 2.4 8.5 5.1 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain CBFD_NFYB_HMF PF00808.23 GAM23171.1 - 5.2e-15 55.5 0.7 8.8e-15 54.8 0.7 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YL1 PF05764.13 GAM23171.1 - 0.0016 18.6 9.5 0.0031 17.7 9.5 1.5 1 0 0 1 1 1 1 YL1 nuclear protein BSP_II PF05432.11 GAM23171.1 - 0.037 13.7 8.7 0.098 12.3 8.7 1.7 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 GAM23171.1 - 0.045 12.1 7.3 0.073 11.4 7.3 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 GAM23171.1 - 0.17 11.8 40.0 1.2 9.0 20.7 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 GAM23171.1 - 0.33 10.7 17.2 0.23 11.2 14.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 GAM23171.1 - 1.6 7.3 27.6 0.027 13.1 19.2 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.12 GAM23171.1 - 1.8 7.8 12.7 3.2 7.0 12.7 1.4 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 GAM23171.1 - 4.9 5.6 10.5 9.6 4.6 10.5 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 GAM23171.1 - 7 5.9 27.2 0.058 12.7 15.0 2.5 2 1 0 2 2 2 0 BUD22 BAR PF03114.18 GAM23172.1 - 1.1e-05 25.2 8.0 6.4e-05 22.7 8.0 1.9 1 1 0 1 1 1 1 BAR domain GATA PF00320.27 GAM23173.1 - 1.3e-15 56.7 3.8 2.5e-15 55.7 3.8 1.5 1 0 0 1 1 1 1 GATA zinc finger TPR_12 PF13424.6 GAM23174.1 - 6.8e-38 128.8 10.9 3.8e-13 49.5 0.5 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat DUF4062 PF13271.6 GAM23174.1 - 4.8e-14 52.5 0.0 4.8e-14 52.5 0.0 3.1 2 1 0 2 2 1 1 Domain of unknown function (DUF4062) TPR_10 PF13374.6 GAM23174.1 - 1.1e-13 50.5 15.1 6.4e-05 22.7 0.2 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM23174.1 - 8.6e-10 38.0 16.2 0.054 13.6 0.0 7.2 8 0 0 8 8 6 4 Tetratricopeptide repeat NACHT PF05729.12 GAM23174.1 - 1.5e-09 38.0 0.0 1.5e-09 38.0 0.0 3.0 2 1 0 2 2 1 1 NACHT domain TPR_1 PF00515.28 GAM23174.1 - 1.9e-09 37.0 18.7 0.0037 17.0 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TIG PF01833.24 GAM23174.1 - 7.7e-09 35.5 2.2 2e-08 34.2 2.2 1.7 1 0 0 1 1 1 1 IPT/TIG domain TPR_8 PF13181.6 GAM23174.1 - 5.5e-08 32.4 17.0 0.051 13.8 0.1 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM23174.1 - 7.9e-07 28.7 6.3 1.5 9.0 0.0 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 GAM23174.1 - 1.9e-06 28.3 0.0 1.9e-06 28.3 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain KAP_NTPase PF07693.14 GAM23174.1 - 0.024 13.9 0.1 0.024 13.9 0.1 3.3 3 1 0 3 3 2 0 KAP family P-loop domain TPR_14 PF13428.6 GAM23174.1 - 0.027 15.3 2.6 78 4.5 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_22 PF13401.6 GAM23174.1 - 0.035 14.4 0.0 0.035 14.4 0.0 3.3 3 0 0 3 3 2 0 AAA domain RsgA_GTPase PF03193.16 GAM23174.1 - 0.04 13.8 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 1 0 RsgA GTPase AAA_29 PF13555.6 GAM23174.1 - 0.061 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain BRCT PF00533.26 GAM23174.1 - 0.18 12.2 0.2 1.3 9.5 0.2 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain ABC_tran PF00005.27 GAM23174.1 - 0.2 12.2 0.0 0.2 12.2 0.0 3.7 2 1 0 2 2 1 0 ABC transporter AAA_33 PF13671.6 GAM23174.1 - 0.74 10.0 0.0 0.74 10.0 0.0 3.8 3 0 0 3 3 2 0 AAA domain TatD_DNase PF01026.21 GAM23175.1 - 7e-43 146.8 0.0 1.9e-42 145.4 0.0 1.7 2 0 0 2 2 2 1 TatD related DNase Amidohydro_2 PF04909.14 GAM23175.1 - 0.014 15.2 0.0 0.087 12.6 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase Astro_capsid_p PF12226.8 GAM23175.1 - 0.026 13.7 8.1 0.042 13.0 8.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TT_ORF2 PF02957.15 GAM23175.1 - 0.061 14.2 4.6 0.19 12.7 4.6 1.8 1 0 0 1 1 1 0 TT viral ORF2 RPA_interact_C PF14768.6 GAM23175.1 - 0.14 12.7 1.0 28 5.4 0.2 2.6 2 0 0 2 2 2 0 Replication protein A interacting C-terminal FCP1_C PF09309.10 GAM23175.1 - 0.2 11.5 17.7 0.055 13.4 10.0 2.2 2 0 0 2 2 2 0 FCP1, C-terminal Pox_Ag35 PF03286.14 GAM23175.1 - 0.31 10.8 16.3 0.39 10.5 11.9 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.6 GAM23175.1 - 0.81 9.3 14.0 0.5 10.0 7.5 2.3 2 0 0 2 2 2 0 FAM176 family GST_C_3 PF14497.6 GAM23176.1 - 1.3e-18 67.0 0.0 2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM23176.1 - 7.5e-07 29.4 0.0 1.6e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM23176.1 - 4.5e-06 26.8 0.1 1.6e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM23176.1 - 0.0098 15.9 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM23176.1 - 0.015 15.7 0.1 0.046 14.1 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.13 GAM23176.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain EB PF01683.18 GAM23177.1 - 0.0032 17.7 1.7 0.0072 16.6 1.7 1.6 1 0 0 1 1 1 1 EB module PRKCSH-like PF12999.7 GAM23177.1 - 0.26 11.1 2.4 0.5 10.1 2.4 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like CorA PF01544.18 GAM23178.1 - 1.1e-44 152.9 6.3 1.7e-44 152.3 6.3 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1129 PF06570.11 GAM23178.1 - 0.041 13.4 0.1 0.077 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4212 PF13937.6 GAM23178.1 - 4.1 7.9 6.5 0.79 10.1 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Copper-bind PF00127.20 GAM23179.1 - 0.00078 19.8 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family SecM PF06558.12 GAM23179.1 - 0.047 13.8 0.1 0.066 13.3 0.1 1.3 1 1 0 1 1 1 0 Secretion monitor precursor protein (SecM) PH_8 PF15409.6 GAM23179.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Ank_2 PF12796.7 GAM23180.1 - 6.5e-11 42.7 2.0 0.00033 21.2 0.0 5.1 5 1 1 6 6 6 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM23180.1 - 5.8e-06 26.7 11.4 0.87 10.2 0.0 6.3 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM23180.1 - 5.1e-05 23.5 5.9 6.4 7.2 0.1 5.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM23180.1 - 0.0002 21.5 7.6 5.8 7.8 0.0 6.7 7 0 0 7 7 7 1 Ankyrin repeat EamA PF00892.20 GAM23181.1 - 1.2e-11 45.0 35.0 3.4e-06 27.3 6.1 2.9 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 GAM23181.1 - 2.3e-08 33.6 6.9 2.3e-08 33.6 6.9 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 GAM23181.1 - 6.7e-07 29.1 15.5 2.6e-06 27.2 11.1 2.5 2 1 0 2 2 2 1 Solute carrier family 35 TPT PF03151.16 GAM23181.1 - 0.0082 15.5 10.0 0.013 14.9 10.0 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF2208 PF09973.9 GAM23181.1 - 0.04 13.5 7.9 0.39 10.3 0.1 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2208) GWT1 PF06423.12 GAM23181.1 - 0.36 10.9 11.3 1.1 9.4 0.8 3.2 2 1 1 4 4 4 0 GWT1 SHMT PF00464.19 GAM23182.1 - 9.5e-184 610.6 0.0 1.1e-183 610.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 GAM23182.1 - 0.0004 19.7 0.0 0.0017 17.7 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 GAM23182.1 - 0.0015 17.6 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Macro PF01661.21 GAM23182.1 - 0.018 15.1 0.0 0.057 13.5 0.0 1.9 1 0 0 1 1 1 0 Macro domain Aminotran_1_2 PF00155.21 GAM23182.1 - 0.13 11.4 0.0 0.45 9.6 0.0 2.0 1 1 0 1 1 1 0 Aminotransferase class I and II FNIP PF05725.12 GAM23183.1 - 2.2e-58 194.2 2.6 8e-11 41.9 0.0 8.0 3 3 8 12 12 12 11 FNIP Repeat HEAT PF02985.22 GAM23184.1 - 1.5e-19 68.3 5.8 2.5e-05 24.2 0.0 10.7 10 1 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 GAM23184.1 - 8.1e-16 58.2 0.0 2.3e-08 34.3 0.0 5.9 5 0 0 5 5 5 2 HEAT-like repeat IBN_N PF03810.19 GAM23184.1 - 7e-14 51.5 0.8 2.8e-13 49.6 0.8 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 GAM23184.1 - 1e-12 48.4 1.6 0.0074 16.9 0.0 6.6 4 3 2 6 6 5 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 GAM23184.1 - 2.7e-12 46.9 0.1 0.0016 18.8 0.0 6.9 4 2 2 6 6 6 3 HEAT repeats CLASP_N PF12348.8 GAM23184.1 - 1.2e-08 34.8 0.5 0.36 10.3 0.0 5.2 4 1 0 4 4 4 2 CLASP N terminal Arm PF00514.23 GAM23184.1 - 5.8e-08 32.5 1.2 0.0004 20.3 0.0 4.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 GAM23184.1 - 8.1e-08 32.5 3.2 0.0012 18.9 0.0 4.4 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 GAM23184.1 - 0.0001 21.6 6.5 0.019 14.1 0.3 3.9 3 2 0 3 3 3 2 RNAPII transcription regulator C-terminal Sec7_N PF12783.7 GAM23184.1 - 0.00015 21.7 3.3 0.029 14.3 0.9 3.8 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal MMS19_N PF14500.6 GAM23184.1 - 0.00087 18.9 1.5 0.29 10.7 0.0 4.0 4 1 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II Proteasom_PSMB PF10508.9 GAM23184.1 - 0.0014 17.2 0.2 0.0014 17.2 0.2 2.3 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit UME PF08064.13 GAM23184.1 - 0.0054 16.6 0.2 1.4 8.9 0.0 4.6 6 0 0 6 6 6 1 UME (NUC010) domain DUF577 PF04510.12 GAM23184.1 - 0.029 14.3 0.1 2.1 8.2 0.1 3.4 2 1 0 2 2 2 0 Family of unknown function (DUF577) FNIP PF05725.12 GAM23185.1 - 1.4e-110 361.2 40.2 9.4e-13 48.1 0.4 12.3 8 2 5 13 13 13 13 FNIP Repeat Kelch_6 PF13964.6 GAM23185.1 - 6.2e-05 23.1 0.4 0.0017 18.5 0.0 3.0 2 1 1 3 3 3 1 Kelch motif Kelch_4 PF13418.6 GAM23185.1 - 7.6e-05 22.6 0.0 0.00033 20.6 0.0 2.2 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM23185.1 - 0.04 13.9 0.2 11 6.1 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 GAM23186.1 - 1.9e-08 34.3 2.8 0.00055 20.1 0.0 4.2 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM23186.1 - 2.3e-06 27.5 4.3 6.2e-05 22.9 0.1 3.3 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM23186.1 - 0.005 16.4 7.0 0.018 14.7 0.0 4.1 5 0 0 5 5 5 1 Kelch motif LOH1CR12 PF10158.9 GAM23187.1 - 0.0058 16.6 1.9 0.0075 16.3 1.2 1.6 1 1 1 2 2 2 1 Tumour suppressor protein FliT PF05400.13 GAM23187.1 - 0.042 14.7 0.7 0.082 13.7 0.2 1.8 2 0 0 2 2 2 0 Flagellar protein FliT ARTD15_N PF18084.1 GAM23187.1 - 0.14 12.5 0.3 0.56 10.5 0.0 2.0 2 0 0 2 2 2 0 ARTD15 N-terminal domain HSP20 PF00011.21 GAM23188.1 - 1.3e-19 70.2 0.0 6.4e-19 68.0 0.0 2.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM23188.1 - 2.4e-10 39.8 0.0 5.2e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Cation_ATPase_C PF00689.21 GAM23189.1 - 3.2e-36 124.8 8.5 3.2e-36 124.8 8.5 3.2 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAM23189.1 - 7.5e-36 123.3 0.1 7.5e-36 123.3 0.1 3.7 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 GAM23189.1 - 4.7e-17 63.0 2.6 8.1e-16 58.9 2.6 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM23189.1 - 1.2e-08 34.5 0.0 2.9e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM23189.1 - 1.2e-08 35.0 3.8 3.7e-05 23.6 1.3 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM23189.1 - 3.5e-08 33.4 0.0 2.5e-06 27.5 0.0 3.2 3 0 0 3 3 3 1 Cation transport ATPase (P-type) TMEM40 PF15817.5 GAM23189.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Transmembrane protein 40 family Phage_holin_2_3 PF16080.5 GAM23189.1 - 0.31 10.8 1.9 0.96 9.3 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DUF962 PF06127.11 GAM23189.1 - 0.57 10.3 3.0 0.75 9.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF962) GpcrRhopsn4 PF10192.9 GAM23190.1 - 3.4e-75 252.8 18.6 3.4e-75 252.8 18.6 1.6 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 GAM23190.1 - 0.018 14.3 17.8 0.063 12.5 17.8 2.0 1 1 0 1 1 1 0 Lung seven transmembrane receptor DUF2569 PF10754.9 GAM23190.1 - 0.027 14.9 0.3 0.027 14.9 0.3 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2569) DUF2427 PF10348.9 GAM23190.1 - 0.11 12.3 6.7 0.27 11.0 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) UFD1 PF03152.14 GAM23192.1 - 3.4e-66 222.0 0.0 4.2e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 bZIP_1 PF00170.21 GAM23194.1 - 0.00023 21.2 9.8 0.00023 21.2 9.8 3.2 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 GAM23194.1 - 0.0022 18.0 11.8 0.0022 18.0 11.8 5.2 5 0 0 5 5 5 1 Basic region leucine zipper TIG PF01833.24 GAM23195.1 - 9e-93 304.5 341.2 9.7e-14 51.2 5.6 25.0 23 1 1 24 24 24 20 IPT/TIG domain Qn_am_d_aIII PF09099.10 GAM23195.1 - 2.1e-05 24.8 4.6 0.019 15.4 0.1 6.6 7 0 0 7 7 7 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain III CHCH PF06747.13 GAM23198.1 - 0.0009 19.3 1.7 0.0024 18.0 1.7 1.7 1 1 1 2 2 2 1 CHCH domain MTCP1 PF08991.10 GAM23198.1 - 0.019 15.2 0.8 0.03 14.6 0.8 1.4 1 1 0 1 1 1 0 Mature-T-Cell Proliferation I type CX9C PF16860.5 GAM23198.1 - 0.021 14.8 1.6 0.036 14.1 1.6 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, EST1_DNA_bind PF10373.9 GAM23198.1 - 0.036 13.5 0.1 0.039 13.4 0.1 1.0 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Dicty_CTDC PF00526.18 GAM23199.1 - 1.3e-16 60.2 191.3 3.8e-08 33.1 10.0 14.3 15 1 0 15 15 15 10 Dictyostelium (slime mold) repeat PA14 PF07691.12 GAM23199.1 - 2.9e-07 30.4 0.0 4.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Integrin_b_cyt PF08725.11 GAM23199.1 - 2.9 7.7 5.5 0.34 10.6 1.1 1.8 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Ras PF00071.22 GAM23203.1 - 5.5e-57 191.9 0.2 6.8e-57 191.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM23203.1 - 6.4e-20 71.6 0.0 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM23203.1 - 2.5e-09 36.8 0.0 3.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM23203.1 - 6.9e-05 22.5 0.3 0.00019 21.1 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM23203.1 - 0.00081 19.3 1.5 0.42 10.5 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM23203.1 - 0.0018 18.3 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAM23203.1 - 0.0076 15.4 0.1 0.38 9.9 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit FERM_M PF00373.18 GAM23204.1 - 1.3e-45 154.6 13.0 1.5e-24 86.7 0.2 3.5 3 0 0 3 3 3 2 FERM central domain FERM_N PF09379.10 GAM23204.1 - 1.3e-24 85.9 1.0 2.6e-13 49.7 0.0 3.7 3 0 0 3 3 3 2 FERM N-terminal domain FERM_f0 PF16511.5 GAM23204.1 - 2.1e-10 40.8 8.0 2.2e-05 24.7 0.2 4.7 4 0 0 4 4 4 3 N-terminal or F0 domain of Talin-head FERM IRS PF02174.17 GAM23204.1 - 3.3e-05 23.7 0.5 0.0065 16.3 0.0 2.8 3 0 0 3 3 3 1 PTB domain (IRS-1 type) ACBP PF00887.19 GAM23204.1 - 0.00023 21.3 0.0 0.039 14.2 0.0 2.9 2 0 0 2 2 2 1 Acyl CoA binding protein Rad60-SLD PF11976.8 GAM23204.1 - 0.053 13.4 3.1 1.1 9.1 0.4 3.3 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like DUF3439 PF11921.8 GAM23204.1 - 0.43 10.5 9.8 1.1 9.2 9.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ubiquitin PF00240.23 GAM23204.1 - 0.55 10.0 6.6 11 5.9 0.9 3.6 4 0 0 4 4 4 0 Ubiquitin family Tir_receptor_C PF07489.11 GAM23204.1 - 1.3 8.9 12.3 0.045 13.7 6.1 1.7 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Sugar_tr PF00083.24 GAM23205.1 - 1.1e-84 284.9 41.4 1.9e-45 155.6 20.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAM23205.1 - 8.3e-34 117.1 39.9 2.3e-27 95.8 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM23205.1 - 5.6e-10 38.4 34.2 2.8e-09 36.0 14.7 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein MFS_4 PF06779.14 GAM23205.1 - 1.4e-07 31.2 16.3 8e-06 25.4 17.2 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Rick_17kDa_Anti PF05433.15 GAM23205.1 - 0.032 14.1 9.1 0.15 11.9 9.1 2.2 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 GAM23205.1 - 5 7.2 13.5 0.19 11.8 1.6 3.2 3 1 0 3 3 3 0 Glycine zipper Gly-zipper_YMGG PF13441.6 GAM23205.1 - 5.1 6.9 11.7 38 4.1 8.0 2.9 2 1 0 2 2 2 0 YMGG-like Gly-zipper Kelch_4 PF13418.6 GAM23206.1 - 3.6e-08 33.3 1.8 2.2e-05 24.3 0.1 3.7 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM23206.1 - 2.9e-07 30.5 5.0 0.0025 18.0 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 GAM23206.1 - 0.0046 16.5 1.6 0.02 14.5 0.0 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAM23206.1 - 0.081 12.9 1.0 10 6.3 0.0 3.4 4 0 0 4 4 4 0 Kelch motif DUF2850 PF11012.8 GAM23206.1 - 0.21 11.9 0.8 4.1 7.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2850) PEGA PF08308.11 GAM23207.1 - 3.3e-05 23.7 0.1 0.00035 20.4 0.0 2.8 2 0 0 2 2 2 1 PEGA domain Sde2_N_Ubi PF13019.6 GAM23208.1 - 7.9e-28 97.3 4.8 7.9e-28 97.3 4.8 2.0 1 1 1 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Latarcin PF10279.9 GAM23208.1 - 0.00063 20.1 1.2 0.0015 18.8 0.5 2.0 1 1 0 1 1 1 1 Latarcin precursor Mucin PF01456.17 GAM23208.1 - 0.029 14.3 12.2 0.025 14.5 11.0 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Macoilin PF09726.9 GAM23208.1 - 0.066 11.8 6.7 0.086 11.4 6.7 1.1 1 0 0 1 1 1 0 Macoilin family FSA_C PF10479.9 GAM23208.1 - 0.12 10.5 3.3 0.16 10.1 3.3 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3439 PF11921.8 GAM23208.1 - 0.31 11.0 5.8 0.61 10.1 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 GAM23208.1 - 1.5 7.0 15.1 1.9 6.6 15.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pkinase PF00069.25 GAM23209.1 - 8.8e-26 90.8 0.0 1.8e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GAM23209.1 - 2.8e-15 56.4 7.0 4.3e-06 27.3 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 GAM23209.1 - 1.6e-10 40.7 0.0 2.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 GAM23209.1 - 1.5e-06 28.4 0.0 0.025 14.9 0.0 4.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PBP_sp32 PF07222.12 GAM23209.1 - 0.034 13.6 1.5 0.084 12.3 1.5 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sigma70_ner PF04546.13 GAM23209.1 - 0.066 13.1 5.8 0.22 11.4 4.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Chromo PF00385.24 GAM23210.1 - 1.9e-13 50.1 4.7 1.7e-11 43.8 1.2 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 GAM23210.1 - 2.6e-10 40.3 0.9 4.6e-08 33.0 0.1 2.3 2 0 0 2 2 2 2 Chromo shadow domain DDE_Tnp_1 PF01609.21 GAM23210.1 - 0.092 12.4 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain GAGA_bind PF06217.12 GAM23210.1 - 0.37 11.0 4.7 0.46 10.7 4.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family WGG PF10273.9 GAM23211.1 - 4.8e-23 81.6 0.1 1e-22 80.6 0.1 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 TFIIA PF03153.13 GAM23211.1 - 0.0017 18.5 12.8 0.0022 18.1 12.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RRP7 PF12923.7 GAM23211.1 - 0.0084 16.2 0.8 0.0084 16.2 0.8 2.1 2 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain USP8_interact PF08941.10 GAM23211.1 - 0.18 11.6 4.1 0.22 11.3 4.1 1.2 1 0 0 1 1 1 0 USP8 interacting CAF20 PF17052.5 GAM23211.1 - 0.36 11.0 5.3 3.5 7.8 0.6 2.4 2 0 0 2 2 2 0 Cap associated factor Herpes_TAF50 PF03326.13 GAM23211.1 - 7.1 5.2 14.8 9.3 4.8 14.8 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Methyltransf_23 PF13489.6 GAM23212.1 - 9.9e-20 71.0 0.0 1.5e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM23212.1 - 2e-18 66.8 0.1 3.5e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM23212.1 - 2.5e-13 50.6 0.0 4.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM23212.1 - 4e-13 49.9 0.1 7.1e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM23212.1 - 7.6e-13 48.5 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAM23212.1 - 1.2e-09 37.9 0.0 1.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 GAM23212.1 - 1.4e-05 24.7 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 GAM23212.1 - 0.0002 20.8 0.0 0.00028 20.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 GAM23212.1 - 0.00027 21.0 0.4 0.00062 19.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAM23212.1 - 0.00064 19.3 0.1 0.0021 17.6 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 GAM23212.1 - 0.0013 17.7 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 GAM23212.1 - 0.0035 16.8 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 GAM23212.1 - 0.0079 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 GAM23212.1 - 0.038 13.6 0.1 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Coatomer_E PF04733.14 GAM23212.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit Ion_trans PF00520.31 GAM23213.1 - 0.22 10.7 2.8 1.4 8.1 0.2 2.1 2 0 0 2 2 2 0 Ion transport protein DUF1201 PF06716.11 GAM23213.1 - 1 9.5 5.2 4.2 7.5 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Pkinase_Tyr PF07714.17 GAM23214.1 - 3.7e-60 203.4 0.1 9.1e-60 202.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GAM23214.1 - 7.9e-52 176.2 0.0 3e-51 174.3 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain RGS PF00615.19 GAM23214.1 - 2.6e-19 69.6 5.1 2.6e-19 69.6 5.1 2.4 3 0 0 3 3 3 1 Regulator of G protein signaling domain Haspin_kinase PF12330.8 GAM23214.1 - 0.00028 20.0 0.0 0.00028 20.0 0.0 4.2 4 1 0 4 4 4 1 Haspin like kinase domain APH PF01636.23 GAM23214.1 - 0.00071 19.6 2.4 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAM23214.1 - 0.0016 17.8 0.0 0.0016 17.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like GpcrRhopsn4 PF10192.9 GAM23214.1 - 0.0065 15.9 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain RIO1 PF01163.22 GAM23214.1 - 0.0078 15.8 0.1 0.0078 15.8 0.1 3.3 4 0 0 4 4 4 2 RIO1 family DUF2232 PF09991.9 GAM23214.1 - 0.3 10.2 0.3 0.73 9.0 0.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ank_2 PF12796.7 GAM23215.1 - 2.4e-07 31.2 1.9 2.8e-05 24.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM23215.1 - 4.9e-07 30.2 0.5 4.7e-05 23.9 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM23215.1 - 2.6e-05 24.4 0.2 0.33 11.3 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) CNOT1_HEAT PF16418.5 GAM23215.1 - 0.0046 17.0 0.5 2.3 8.3 0.0 2.5 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 HEAT repeat SUIM_assoc PF16619.5 GAM23215.1 - 0.018 15.1 0.1 0.046 13.8 0.1 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ank_3 PF13606.6 GAM23215.1 - 0.048 14.2 1.6 32 5.6 0.0 4.6 5 0 0 5 5 5 0 Ankyrin repeat CobU PF02283.16 GAM23215.1 - 0.12 12.0 0.4 0.32 10.5 0.1 1.9 1 1 1 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase NIF PF03031.18 GAM23216.1 - 2.7e-17 63.0 0.4 8.2e-17 61.4 0.4 1.8 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 GAM23216.1 - 2.6e-13 50.1 0.1 1.2e-12 48.0 0.1 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAM23216.1 - 5.3e-08 32.7 0.1 1.2e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 GAM23216.1 - 0.0025 18.2 0.0 0.012 16.0 0.0 2.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 GAM23216.1 - 0.76 9.7 4.8 0.51 10.2 0.1 2.8 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain bZIP_1 PF00170.21 GAM23217.1 - 4.2e-06 26.8 3.9 4.2e-06 26.8 3.9 3.8 4 0 0 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 GAM23217.1 - 3.8e-05 23.7 7.0 3.8e-05 23.7 7.0 4.6 5 0 0 5 5 5 1 Basic region leucine zipper NADH_dhqG_C PF09326.11 GAM23217.1 - 5.6 7.7 0.0 5.6 7.7 0.0 4.2 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase subunit G, C-terminal SAE2 PF08573.10 GAM23218.1 - 3.9e-09 37.6 5.1 7.8e-06 27.0 0.1 4.8 2 2 1 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus DsbG_N PF18257.1 GAM23218.1 - 0.035 14.2 4.2 0.32 11.2 2.7 2.9 3 1 0 3 3 3 0 Disulfide isomerase DsbG N-terminal SWIB PF02201.18 GAM23218.1 - 0.058 13.3 1.3 0.17 11.8 0.1 2.3 2 0 0 2 2 2 0 SWIB/MDM2 domain DWNN PF08783.11 GAM23219.1 - 1.6e-13 50.7 3.0 9.6e-13 48.2 0.1 2.7 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 GAM23219.1 - 1.3e-10 40.9 10.4 2.3e-10 40.1 10.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GAM23219.1 - 0.00066 19.6 3.6 0.00066 19.6 3.6 1.9 2 0 0 2 2 2 1 Zinc knuckle Eapp_C PF10238.9 GAM23219.1 - 0.0069 16.5 1.5 0.0069 16.5 1.5 3.0 1 1 2 3 3 3 1 E2F-associated phosphoprotein Gti1_Pac2 PF09729.9 GAM23219.1 - 0.037 14.1 0.4 0.072 13.2 0.1 1.6 2 0 0 2 2 2 0 Gti1/Pac2 family zf-C3HC4 PF00097.25 GAM23219.1 - 0.18 11.7 10.6 0.48 10.3 10.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 GAM23219.1 - 0.27 11.3 12.7 2.9 8.0 2.0 3.2 2 1 1 3 3 3 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 GAM23219.1 - 1.1 9.5 9.2 3 8.1 9.2 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAM23219.1 - 2.7 8.4 11.0 0.18 12.1 5.7 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf_UBZ PF18439.1 GAM23219.1 - 4.6 6.9 6.7 22 4.8 0.3 3.4 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger AD PF09793.9 GAM23220.1 - 9.6e-24 83.3 0.0 1.5e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain PEP-utilisers_N PF05524.13 GAM23220.1 - 0.029 14.6 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Cyt-b5 PF00173.28 GAM23221.1 - 2.8e-19 69.0 0.0 6.6e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zip PF02535.22 GAM23221.1 - 0.056 12.7 3.2 0.072 12.3 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 GAM23221.1 - 2.8 7.3 14.6 2.5 7.4 13.3 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF3591 PF12157.8 GAM23222.1 - 3.3e-145 484.1 0.0 3.3e-145 484.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 GAM23222.1 - 2.9e-15 56.1 0.4 1.1e-14 54.2 0.4 2.0 1 0 0 1 1 1 1 Bromodomain TBP-binding PF09247.11 GAM23222.1 - 4.4e-05 23.6 1.5 4.4e-05 23.6 1.5 2.3 2 0 0 2 2 2 1 TATA box-binding protein binding SUIM_assoc PF16619.5 GAM23222.1 - 0.0022 18.0 0.0 1.4 9.0 0.0 4.6 4 1 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 AAA_2 PF07724.14 GAM23223.1 - 7.2e-58 195.5 0.0 2.8e-53 180.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAM23223.1 - 4.6e-36 122.9 0.9 4.6e-36 122.9 0.9 2.6 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 GAM23223.1 - 6.1e-27 94.6 0.0 1.6e-14 54.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 GAM23223.1 - 7.8e-22 77.2 5.9 9.2e-13 48.1 0.3 2.9 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component ClpB_D2-small PF10431.9 GAM23223.1 - 5.5e-21 74.4 0.1 5.5e-21 74.4 0.1 3.2 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAM23223.1 - 6.3e-19 68.3 0.2 4.4e-12 46.2 0.0 3.5 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM23223.1 - 1.1e-11 45.4 9.1 1.9e-06 28.3 0.1 5.2 4 3 1 6 6 6 2 AAA ATPase domain Sigma54_activat PF00158.26 GAM23223.1 - 3.1e-10 40.0 0.0 1.9e-06 27.7 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 GAM23223.1 - 5.1e-09 36.5 0.0 0.019 15.2 0.0 4.4 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 GAM23223.1 - 6.3e-08 32.6 0.0 0.0076 16.0 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 GAM23223.1 - 1.2e-06 28.6 0.0 0.046 13.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 GAM23223.1 - 3.3e-06 26.9 0.5 0.1 12.3 0.0 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 GAM23223.1 - 3.7e-06 26.5 0.0 0.0055 16.1 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 GAM23223.1 - 9.4e-06 26.2 0.0 0.079 13.5 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAM23223.1 - 1.7e-05 24.4 0.0 0.036 13.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 GAM23223.1 - 5.8e-05 23.1 0.0 0.2 11.6 0.0 2.8 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 GAM23223.1 - 9.4e-05 22.8 0.0 1.2 9.6 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_33 PF13671.6 GAM23223.1 - 0.00041 20.5 0.0 0.6 10.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 GAM23223.1 - 0.00049 19.7 0.1 0.12 11.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 GAM23223.1 - 0.00071 19.4 0.0 0.46 10.4 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 GAM23223.1 - 0.00097 19.1 8.9 0.38 10.6 0.1 4.6 4 2 1 6 6 5 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 GAM23223.1 - 0.00098 19.4 0.5 4.4 7.5 0.0 3.6 4 0 0 4 4 3 0 AAA domain TsaE PF02367.17 GAM23223.1 - 0.00099 19.1 0.1 3.3 7.7 0.0 3.2 4 0 0 4 4 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 GAM23223.1 - 0.001 19.3 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GAM23223.1 - 0.0021 18.0 0.0 5.7 6.8 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase Zeta_toxin PF06414.12 GAM23223.1 - 0.0022 17.3 0.0 0.26 10.6 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 GAM23223.1 - 0.0023 17.7 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAM23223.1 - 0.0028 17.1 0.0 1.9 7.8 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta2 PF13177.6 GAM23223.1 - 0.0038 17.0 0.0 0.052 13.3 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit ABC_tran PF00005.27 GAM23223.1 - 0.0051 17.3 0.5 1.7 9.1 0.0 3.9 4 1 0 4 4 3 1 ABC transporter DUF87 PF01935.17 GAM23223.1 - 0.0059 16.7 6.3 0.33 11.0 0.0 4.0 4 0 0 4 4 4 1 Helicase HerA, central domain ResIII PF04851.15 GAM23223.1 - 0.013 15.5 0.0 1.1 9.2 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 GAM23223.1 - 0.017 15.7 15.6 0.086 13.3 0.0 3.9 2 2 0 2 2 1 0 AAA domain SRP54 PF00448.22 GAM23223.1 - 0.038 13.6 0.1 11 5.5 0.0 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 GAM23223.1 - 0.039 14.3 0.2 0.85 9.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 GAM23223.1 - 0.042 12.9 0.1 0.19 10.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 GAM23223.1 - 0.074 12.5 0.0 1.2 8.5 0.0 2.8 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.6 GAM23223.1 - 0.086 12.6 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rx_N PF18052.1 GAM23223.1 - 0.087 13.1 3.9 2.1 8.7 4.7 2.7 2 0 0 2 2 2 0 Rx N-terminal domain NodS PF05401.11 GAM23223.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) FTA4 PF13093.6 GAM23223.1 - 0.25 11.2 7.3 0.18 11.7 4.9 2.0 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RhoGAP PF00620.27 GAM23225.1 - 6.7e-35 120.2 0.7 2.4e-34 118.4 0.1 2.3 2 0 0 2 2 2 1 RhoGAP domain RhoGEF PF00621.20 GAM23225.1 - 6e-30 104.8 7.0 8.1e-30 104.4 2.2 2.9 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 GAM23225.1 - 3e-06 27.7 0.3 6.3e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 PH domain IQ PF00612.27 GAM23225.1 - 0.003 17.2 0.2 0.0082 15.9 0.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH_10 PF15411.6 GAM23225.1 - 0.054 13.8 0.3 0.18 12.1 0.3 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain VASt PF16016.5 GAM23226.1 - 1.8e-15 57.6 1.7 1.8e-15 57.6 1.7 2.8 3 1 0 3 3 3 1 VAD1 Analog of StAR-related lipid transfer domain ATG16 PF08614.11 GAM23226.1 - 0.014 15.7 6.6 0.014 15.7 6.6 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4145 PF13643.6 GAM23226.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) DUF4164 PF13747.6 GAM23226.1 - 0.12 12.6 2.4 0.18 12.1 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF4011 PF13195.6 GAM23226.1 - 0.69 9.8 6.4 0.75 9.7 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Androgen_recep PF02166.16 GAM23226.1 - 1.1 8.0 15.1 0.47 9.3 12.9 1.4 1 1 0 1 1 1 0 Androgen receptor FtsJ PF01728.19 GAM23227.1 - 1e-29 103.9 0.0 1.7e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase YtxH PF12732.7 GAM23227.1 - 0.19 12.3 0.0 0.57 10.7 0.0 1.8 2 0 0 2 2 2 0 YtxH-like protein DUF4834 PF16118.5 GAM23228.1 - 0.0065 17.4 0.2 0.014 16.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Profilin PF00235.19 GAM23229.1 - 2.8e-07 30.8 0.0 3.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Profilin Na_K-ATPase PF00287.18 GAM23229.1 - 0.0045 16.2 0.1 0.0053 16.0 0.1 1.1 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain Rbsn PF11464.8 GAM23229.1 - 0.056 13.2 0.1 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 Rabenosyn Rab binding domain BRCT_2 PF16589.5 GAM23230.1 - 1.5e-13 50.9 0.0 1.1e-09 38.6 0.0 3.0 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain CSRNP_N PF16019.5 GAM23230.1 - 0.019 14.9 0.6 0.019 14.9 0.6 3.0 3 0 0 3 3 3 0 Cysteine/serine-rich nuclear protein N-terminus LIG3_BRCT PF16759.5 GAM23230.1 - 0.16 12.3 1.6 5.2 7.4 0.0 3.5 4 0 0 4 4 4 0 DNA ligase 3 BRCT domain Coiled PF05710.12 GAM23231.1 - 0.036 14.9 6.2 0.043 14.6 6.2 1.1 1 0 0 1 1 1 0 Coiled coil Xpo1 PF08389.12 GAM23232.1 - 4.8e-36 124.1 1.1 4.8e-36 124.1 1.1 4.3 4 1 1 5 5 5 1 Exportin 1-like protein DUF3385 PF11865.8 GAM23232.1 - 0.27 11.1 0.1 0.27 11.1 0.1 4.3 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) Epimerase PF01370.21 GAM23233.1 - 1e-24 87.3 0.0 3.9e-24 85.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM23233.1 - 1e-17 64.6 0.1 5.1e-08 32.7 0.0 3.1 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAM23233.1 - 3.8e-17 62.3 0.0 4.1e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 GAM23233.1 - 7.3e-11 41.6 0.0 4.9e-05 22.5 0.0 2.9 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAM23233.1 - 9.8e-09 34.7 0.0 0.00011 21.5 0.0 2.7 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAM23233.1 - 4.3e-06 26.7 0.0 0.03 14.2 0.0 3.0 3 0 0 3 3 3 2 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAM23233.1 - 2.2e-05 23.7 0.0 6e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 GAM23233.1 - 0.0085 15.7 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 GAM23233.1 - 0.019 15.4 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM23233.1 - 0.14 12.2 0.0 0.71 10.0 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 GAM23233.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 KR domain IMUP PF15761.5 GAM23233.1 - 2.4 8.9 16.9 0.84 10.4 2.7 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein FKBP_C PF00254.28 GAM23234.1 - 6.1e-36 122.6 0.1 7e-36 122.4 0.1 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase G-alpha PF00503.20 GAM23235.1 - 2.4e-100 336.1 5.8 3e-100 335.8 5.8 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM23235.1 - 1.1e-12 47.7 0.5 2e-08 33.9 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM23235.1 - 0.023 14.8 0.1 8.5 6.5 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 GAM23235.1 - 0.028 14.6 0.0 8.9 6.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 GAM23235.1 - 0.057 13.0 0.2 0.26 10.8 0.2 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAM23235.1 - 0.065 12.7 0.9 3.1 7.2 0.1 2.8 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit Nucleoporin2 PF04096.14 GAM23236.1 - 5.7e-43 146.6 0.0 1.2e-42 145.5 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin autopeptidase ApoL PF05461.11 GAM23236.1 - 0.011 15.1 0.7 0.017 14.5 0.7 1.2 1 0 0 1 1 1 0 Apolipoprotein L HTH_55 PF18622.1 GAM23237.1 - 2.5 8.5 5.4 1e+02 3.3 0.1 5.1 2 2 2 5 5 5 0 RctB helix turn helix domain TIG PF01833.24 GAM23238.1 - 2e-98 322.6 82.5 1.5e-14 53.8 3.6 13.3 11 0 0 11 11 11 11 IPT/TIG domain SdrD_B PF17210.3 GAM23238.1 - 0.00012 22.3 1.5 0.00012 22.3 1.5 3.9 3 0 0 3 3 3 1 SdrD B-like domain TIG PF01833.24 GAM23239.1 - 8e-69 227.7 109.1 1.2e-09 38.1 0.6 17.8 19 1 0 19 19 19 13 IPT/TIG domain DNase_II PF03265.15 GAM23239.1 - 5.6e-40 137.6 0.6 9.1e-23 81.0 0.3 2.6 2 0 0 2 2 2 2 Deoxyribonuclease II SdrD_B PF17210.3 GAM23239.1 - 1.8e-22 79.7 7.5 8.9e-10 38.8 0.1 4.9 4 0 0 4 4 4 3 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM23239.1 - 5.8e-06 26.5 28.4 8.5e-06 26.0 3.0 5.8 7 0 0 7 7 7 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 GAM23239.1 - 6.8e-05 22.8 1.5 0.47 10.5 0.0 3.8 3 1 0 3 3 3 2 CarboxypepD_reg-like domain DUF2012 PF09430.10 GAM23239.1 - 0.0031 17.6 0.1 2.7 8.1 0.1 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2012) SpaA PF17802.1 GAM23239.1 - 0.31 11.4 8.0 0.99 9.8 0.4 3.6 3 0 0 3 3 3 0 Prealbumin-like fold domain Acyl_CoA_thio PF02551.15 GAM23240.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA thioesterase Lipase_3 PF01764.25 GAM23241.1 - 2.9e-31 108.2 0.0 3.9e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GAM23241.1 - 2.3e-06 27.3 0.0 3.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 GAM23241.1 - 0.0041 17.8 0.3 0.007 17.0 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 GAM23241.1 - 0.021 14.8 0.1 0.042 13.8 0.1 1.6 1 1 0 1 1 1 0 Cutinase PGAP1 PF07819.13 GAM23241.1 - 0.05 13.3 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Complex1_51K PF01512.17 GAM23241.1 - 0.097 12.5 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit DIL PF01843.19 GAM23242.1 - 6.3e-11 42.5 3.6 1.5e-10 41.2 3.6 1.6 1 0 0 1 1 1 1 DIL domain NT-C2 PF10358.9 GAM23242.1 - 3e-09 36.8 0.0 6.8e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF4911 PF16256.5 GAM23242.1 - 0.077 13.0 0.0 0.31 11.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Pirin PF02678.16 GAM23243.1 - 8.4e-37 125.5 1.1 2.2e-36 124.1 0.7 1.9 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 GAM23243.1 - 6.2e-31 106.8 0.1 1.4e-29 102.5 0.0 2.4 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 GAM23243.1 - 0.0046 16.6 1.1 0.88 9.3 0.4 2.4 2 0 0 2 2 2 2 Cupin domain Ribosomal_S25 PF03297.15 GAM23244.1 - 1.7e-35 121.3 2.2 1.9e-35 121.1 2.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Rrf2 PF02082.20 GAM23244.1 - 0.12 12.7 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator ANAPC4_WD40 PF12894.7 GAM23245.1 - 3.6e-10 40.0 1.7 0.0043 17.3 0.1 3.9 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM23245.1 - 6.8e-09 36.2 17.0 0.0026 18.6 0.9 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 GAM23245.1 - 0.00034 20.6 3.9 0.32 10.9 0.0 4.1 3 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A LytB_WW PF18342.1 GAM23245.1 - 0.0073 16.4 0.1 6.4 7.0 0.0 3.3 3 0 0 3 3 3 1 Endo-beta-N-acetylglucosaminidase LytB WW domain SnoaL_2 PF12680.7 GAM23245.1 - 0.096 13.3 0.2 0.22 12.2 0.2 1.6 1 0 0 1 1 1 0 SnoaL-like domain DPPIV_N PF00930.21 GAM23245.1 - 0.39 9.4 3.7 0.45 9.2 2.1 1.9 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Dynamitin PF04912.14 GAM23246.1 - 4.8e-100 335.6 15.0 5.5e-100 335.4 15.0 1.0 1 0 0 1 1 1 1 Dynamitin FAM76 PF16046.5 GAM23246.1 - 3.9 6.7 8.7 3.9 6.7 2.5 2.2 2 0 0 2 2 2 0 FAM76 protein APC_N_CC PF16689.5 GAM23246.1 - 4.4 7.5 9.2 1.1 9.4 2.1 3.3 3 1 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain UQ_con PF00179.26 GAM23247.1 - 0.044 13.4 0.1 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme BioW PF03744.13 GAM23247.1 - 0.14 11.7 0.8 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 6-carboxyhexanoate--CoA ligase FNIP PF05725.12 GAM23248.1 - 4e-14 52.5 10.6 3.3e-05 24.0 0.3 6.8 4 3 1 6 6 6 5 FNIP Repeat LRR_8 PF13855.6 GAM23248.1 - 0.71 9.7 6.3 29 4.5 0.1 4.1 3 1 0 3 3 3 0 Leucine rich repeat TLD PF07534.16 GAM23250.1 - 6.5e-33 113.9 1.0 1.2e-32 113.1 1.0 1.4 1 0 0 1 1 1 1 TLD FH2 PF02181.23 GAM23251.1 - 9.2e-84 281.7 12.7 1.9e-83 280.6 12.7 1.6 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 GAM23251.1 - 2.6e-15 56.5 0.6 2.6e-15 56.5 0.6 3.3 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 GAM23251.1 - 5.8e-11 42.3 0.7 5.8e-11 42.3 0.7 2.5 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain FHA PF00498.26 GAM23251.1 - 4.9e-09 36.4 0.1 4.3e-08 33.4 0.0 2.5 2 0 0 2 2 2 1 FHA domain DUF5071 PF16804.5 GAM23251.1 - 0.033 14.4 1.1 5.9 7.2 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF5071) DUF2400 PF09674.10 GAM23251.1 - 2.3 8.2 5.3 7.5 6.5 1.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2400) Fmp27_WPPW PF10359.9 GAM23252.1 - 0.00075 18.5 0.2 0.00075 18.5 0.2 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Chorion_2 PF03964.15 GAM23252.1 - 0.0061 17.4 1.5 0.0061 17.4 1.5 2.9 2 1 0 2 2 2 1 Chorion family 2 Cluap1 PF10234.9 GAM23252.1 - 0.14 11.5 9.1 0.23 10.8 9.1 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 ASD2 PF08687.11 GAM23252.1 - 0.33 10.5 7.9 0.087 12.4 5.0 1.6 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Prominin PF05478.11 GAM23252.1 - 6 4.7 9.5 3.7 5.4 5.8 1.9 2 0 0 2 2 2 0 Prominin Bud13 PF09736.9 GAM23253.1 - 4.7e-45 153.5 15.6 4.7e-45 153.5 15.6 3.7 3 1 1 4 4 4 1 Pre-mRNA-splicing factor of RES complex PI3Ka PF00613.20 GAM23254.1 - 6.5e-55 185.4 4.0 6.5e-55 185.4 4.0 1.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 GAM23254.1 - 1.3e-54 185.6 0.0 1.1e-51 176.1 0.0 2.8 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 GAM23254.1 - 3.9e-34 117.5 0.0 8.5e-34 116.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 CBM49 PF09478.10 GAM23255.1 - 2.2e-11 43.9 0.3 3.1e-11 43.4 0.3 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM49 PF09478.10 GAM23256.1 - 1.1e-11 44.9 0.4 1.5e-11 44.4 0.4 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 NAD_binding_5 PF07994.12 GAM23257.1 - 6.3e-143 476.0 0.0 7.3e-143 475.8 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 GAM23257.1 - 5.5e-48 161.8 0.3 1.1e-47 160.8 0.3 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DNA_pol_A_exo1 PF01612.20 GAM23258.1 - 4.3e-38 130.8 0.5 5.9e-38 130.3 0.5 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 GAM23258.1 - 1.3e-07 31.5 0.0 6.5e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 HRDC domain Aminotran_1_2 PF00155.21 GAM23260.1 - 8e-40 137.1 0.0 1.1e-39 136.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAM23260.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Leo1 PF04004.13 GAM23261.1 - 6.4e-40 136.7 0.2 6.4e-40 136.7 0.2 3.9 3 1 1 4 4 4 1 Leo1-like protein CD34_antigen PF06365.12 GAM23262.1 - 0.0048 16.5 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 CD34/Podocalyxin family EphA2_TM PF14575.6 GAM23262.1 - 0.049 14.5 0.1 0.092 13.6 0.1 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.11 GAM23262.1 - 0.2 11.6 0.4 0.52 10.3 0.1 1.8 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 IPTL-CTERM PF18203.1 GAM23262.1 - 0.3 11.0 4.8 0.77 9.7 4.8 1.7 1 0 0 1 1 1 0 IPTL-CTERM motif Adeno_E3_CR2 PF02439.15 GAM23262.1 - 0.32 10.8 0.9 0.59 9.9 0.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Peptidase_C1 PF00112.23 GAM23263.1 - 5e-48 164.1 0.9 5e-48 164.1 0.9 2.0 1 1 1 2 2 2 1 Papain family cysteine protease CAP PF00188.26 GAM23263.1 - 5e-09 37.1 5.8 1.2e-08 35.8 5.8 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF445 PF04286.12 GAM23264.1 - 0.03 14.1 0.4 0.066 13.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Helicase_C PF00271.31 GAM23265.1 - 9.4e-26 90.3 0.0 2.4e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM23265.1 - 1.5e-25 90.0 1.0 3.3e-25 88.8 1.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM23265.1 - 0.00012 22.2 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAM23265.1 - 0.089 13.1 0.1 0.29 11.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain Guanylate_cyc PF00211.20 GAM23266.1 - 1.9e-83 278.6 1.4 7.6e-45 152.8 0.3 3.0 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 GAM23266.1 - 0.0078 15.7 0.1 0.0078 15.7 0.1 3.1 3 1 0 3 3 3 2 Heme NO binding associated Ank_2 PF12796.7 GAM23267.1 - 3.6e-09 37.1 0.1 3.8e-07 30.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM23267.1 - 6.8e-08 32.9 0.0 0.00022 21.7 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM23267.1 - 7.3e-07 29.3 0.0 2.2e-05 24.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM23267.1 - 9.2e-06 25.9 0.1 0.00028 21.2 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 GAM23267.1 - 0.0002 21.5 0.1 0.021 15.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Peptidase_M1 PF01433.20 GAM23269.1 - 5.5e-11 42.5 0.1 5.5e-11 42.5 0.1 2.7 3 0 0 3 3 3 1 Peptidase family M1 domain MaoC_dehydratas PF01575.19 GAM23270.1 - 8.1e-21 73.9 0.0 9.3e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GAM23270.1 - 3.4e-06 27.2 0.0 4.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 GAM23270.1 - 0.071 13.5 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 Thioesterase superfamily Myb_DNA-binding PF00249.31 GAM23271.1 - 4.3e-10 39.6 0.0 9.8e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM23271.1 - 9.9e-05 22.5 2.5 0.00011 22.3 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM23271.1 - 0.058 13.3 0.1 0.058 13.3 0.1 2.3 3 0 0 3 3 3 0 Myb DNA-binding like DUF3452 PF11934.8 GAM23271.1 - 3.6 7.1 5.1 0.49 9.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) Y_phosphatase2 PF03162.13 GAM23272.1 - 2.4e-55 186.6 0.0 2.8e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GAM23272.1 - 0.0094 15.9 0.0 0.028 14.4 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAM23272.1 - 0.18 11.3 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase tRNA_int_endo PF01974.17 GAM23273.1 - 8.2e-23 80.3 0.0 2e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 GAM23273.1 - 2.7e-08 33.4 1.4 5.7e-06 25.9 0.4 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain E1-E2_ATPase PF00122.20 GAM23274.1 - 4.7e-49 166.4 4.1 6.5e-49 165.9 1.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAM23274.1 - 8.6e-18 65.4 0.2 2.7e-17 63.8 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM23274.1 - 1.7e-12 46.8 0.0 3.5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM23274.1 - 0.0016 18.2 2.0 0.0027 17.5 0.1 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM23274.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) OHA PF14418.6 GAM23275.1 - 0.1 12.4 0.0 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 OST-HTH Associated domain UPF0086 PF01868.16 GAM23276.1 - 2.4e-28 97.9 0.0 7e-28 96.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Methyltransf_15 PF09445.10 GAM23277.1 - 2.6e-36 124.7 0.1 4.7e-36 123.8 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 GAM23277.1 - 4.3e-06 26.6 0.2 0.00018 21.2 0.2 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 GAM23277.1 - 7.8e-06 25.6 0.0 2.1e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 GAM23277.1 - 0.0011 19.7 0.0 0.0023 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 GAM23277.1 - 0.051 13.0 5.2 0.068 12.6 0.0 2.4 2 1 0 2 2 2 0 RRNA methyltransferase AviRa Methyltransf_11 PF08241.12 GAM23277.1 - 0.063 13.9 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 GAM23277.1 - 0.087 12.2 0.1 0.087 12.2 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 GAM23277.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein PTPRCAP PF15713.5 GAM23277.1 - 0.17 12.2 12.5 0.28 11.5 12.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 GAM23277.1 - 0.59 8.4 15.8 0.77 8.0 15.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 GAM23277.1 - 1.6 8.7 10.7 2.4 8.2 10.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region hDGE_amylase PF14701.6 GAM23279.1 - 3.5e-159 530.6 0.2 5e-159 530.1 0.2 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 GAM23279.1 - 8.4e-108 360.7 0.0 1.4e-107 360.0 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 GAM23279.1 - 1.2e-62 211.8 0.0 1.9e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 GAM23279.1 - 8.5e-06 25.8 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme HOOK PF05622.12 GAM23281.1 - 0.00034 18.9 28.0 0.00044 18.6 28.0 1.2 1 0 0 1 1 1 1 HOOK protein PKcGMP_CC PF16808.5 GAM23281.1 - 0.013 15.3 3.5 0.013 15.3 3.5 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TSC22 PF01166.18 GAM23281.1 - 0.056 13.8 2.5 0.056 13.8 2.5 4.0 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF4407 PF14362.6 GAM23281.1 - 0.44 9.8 23.1 0.59 9.4 23.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 GAM23281.1 - 0.67 10.1 30.3 1.2 9.3 1.2 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_CLD PF14073.6 GAM23281.1 - 3.6 7.6 35.2 0.46 10.5 23.4 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 SlyX PF04102.12 GAM23281.1 - 3.9 8.2 32.7 0.5 11.0 0.8 3.8 2 1 1 3 3 3 0 SlyX DUF2849 PF11011.8 GAM23281.1 - 5.8 7.7 7.6 1.2 9.8 0.3 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF2849) ANAPC4_WD40 PF12894.7 GAM23282.1 - 0.0013 19.0 0.2 0.021 15.1 0.1 3.0 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Dscam_C PF12355.8 GAM23283.1 - 0.037 15.0 0.6 0.057 14.4 0.6 1.2 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Dicty_spore_N PF04562.12 GAM23284.1 - 4.7e-13 49.8 9.8 4.7e-13 49.8 9.8 3.6 3 1 0 3 3 3 1 Dictyostelium spore coat protein, N terminus NCD3G PF07562.14 GAM23284.1 - 0.0044 16.9 4.0 0.0044 16.9 4.0 3.7 4 0 0 4 4 4 2 Nine Cysteines Domain of family 3 GPCR CytochromB561_N PF09786.9 GAM23285.1 - 1.4e-08 34.2 13.2 1.4e-08 34.2 13.2 3.1 1 1 0 2 2 2 1 Cytochrome B561, N terminal Ank_2 PF12796.7 GAM23286.1 - 1.1e-17 64.3 0.4 1.2e-13 51.4 0.1 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) ACBP PF00887.19 GAM23286.1 - 5e-17 61.9 0.0 1.1e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Ank PF00023.30 GAM23286.1 - 3.4e-14 52.5 0.5 1.9e-06 28.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAM23286.1 - 7.4e-13 48.5 0.3 3.9e-08 33.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM23286.1 - 1.3e-12 48.0 0.2 3.9e-07 30.5 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM23286.1 - 1.6e-10 40.3 0.1 0.00073 19.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Jak1_Phl PF17887.1 GAM23286.1 - 0.19 11.7 5.9 0.36 10.8 0.0 2.6 1 1 1 3 3 3 0 Jak1 pleckstrin homology-like domain SSP160 PF06933.11 GAM23286.1 - 0.27 9.4 2.8 0.32 9.1 2.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 GAM23286.1 - 0.58 8.1 4.2 0.71 7.8 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4834 PF16118.5 GAM23286.1 - 0.63 11.0 3.7 1.1 10.3 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RR_TM4-6 PF06459.12 GAM23286.1 - 5.2 6.8 7.7 6.2 6.6 7.1 1.3 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1996 PF09362.10 GAM23288.1 - 4.4e-29 102.1 0.0 8.9e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF4512 PF14975.6 GAM23288.1 - 0.64 10.8 3.5 1.3 9.8 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Mucin PF01456.17 GAM23288.1 - 2.8 7.9 22.8 5 7.1 22.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 GAM23288.1 - 9.2 6.7 10.7 5.5 7.4 8.5 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PolC_DP2 PF03833.13 GAM23290.1 - 0.019 12.8 0.4 0.023 12.6 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 CR6_interact PF10147.9 GAM23290.1 - 0.026 14.2 0.6 0.039 13.7 0.6 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 CBM49 PF09478.10 GAM23292.1 - 8.6e-17 61.2 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Ank_2 PF12796.7 GAM23293.1 - 4.8e-42 142.4 35.0 1.5e-09 38.3 0.3 5.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM23293.1 - 1.7e-40 136.9 14.5 3.8e-08 33.7 0.0 8.2 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM23293.1 - 2.5e-37 126.4 22.2 0.0027 18.0 0.0 13.1 2 1 13 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM23293.1 - 2.8e-21 73.3 9.0 1.1 10.0 0.0 13.0 13 2 2 15 15 15 3 Ankyrin repeat DUF5049 PF16468.5 GAM23293.1 - 5.8e-08 32.5 4.0 5.9 6.9 0.1 9.5 5 3 7 12 12 12 1 Domain of unknown function (DUF5049) Ank PF00023.30 GAM23293.1 - 7.5e-08 32.5 8.5 17 6.1 0.1 9.8 3 2 2 6 6 6 1 Ankyrin repeat Phage_Cox PF10743.9 GAM23293.1 - 0.048 13.8 0.0 20 5.4 0.0 4.3 4 2 3 7 7 7 0 Regulatory phage protein cox Ret2_MD PF18528.1 GAM23293.1 - 0.14 12.5 0.2 7 7.1 0.0 3.3 3 2 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain zf_CCCH_5 PF18384.1 GAM23293.1 - 1.4 9.1 4.5 43 4.3 0.0 4.8 6 0 0 6 6 6 0 Unkempt Zinc finger domain 1 (Znf1) TLD PF07534.16 GAM23294.1 - 3.5e-39 134.2 3.1 1.2e-38 132.5 3.1 2.0 1 0 0 1 1 1 1 TLD LysM PF01476.20 GAM23294.1 - 1.9e-06 27.8 0.7 8.3e-06 25.8 0.0 2.5 3 0 0 3 3 3 1 LysM domain Spt20 PF12090.8 GAM23294.1 - 0.0028 17.3 10.8 0.0028 17.3 10.8 2.0 2 0 0 2 2 2 1 Spt20 family Zip PF02535.22 GAM23294.1 - 3.2 6.9 14.5 0.089 12.0 5.5 2.5 3 0 0 3 3 3 0 ZIP Zinc transporter CFIA_Pcf11 PF11526.8 GAM23294.1 - 5.5 7.5 26.4 0.8 10.2 2.6 3.6 3 0 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 DUF4419 PF14388.6 GAM23295.1 - 3.7e-78 263.0 0.4 1.3e-68 231.6 0.5 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) GrpE PF01025.19 GAM23295.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 GrpE DUF4419 PF14388.6 GAM23296.1 - 4e-93 312.2 0.1 4.6e-93 312.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) GrpE PF01025.19 GAM23296.1 - 0.22 11.2 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 GrpE DUF2009 PF09418.10 GAM23297.1 - 2.6e-197 656.4 0.1 3.6e-197 655.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 GAM23297.1 - 1.4e-05 25.1 4.8 2.5e-05 24.3 4.8 1.4 1 0 0 1 1 1 1 B-box zinc finger Flag1_repress PF03614.13 GAM23297.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Repressor of phase-1 flagellin zf-piccolo PF05715.13 GAM23297.1 - 0.1 12.7 5.7 0.83 9.8 5.5 2.5 2 1 0 2 2 2 0 Piccolo Zn-finger Laminin_EGF PF00053.24 GAM23297.1 - 0.29 11.3 11.8 0.57 10.4 11.8 1.4 1 0 0 1 1 1 0 Laminin EGF domain CENP-B_dimeris PF09026.10 GAM23297.1 - 1.5 9.3 7.8 5.7 7.4 0.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain IBR PF01485.21 GAM23297.1 - 3.1 8.1 8.5 10 6.4 8.5 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF3439 PF11921.8 GAM23298.1 - 2 8.4 22.7 0.44 10.5 8.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HPS3_Mid PF14762.6 GAM23299.1 - 9.6e-38 129.9 1.3 1.9e-37 129.0 1.3 1.5 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.6 GAM23299.1 - 7.7e-31 107.3 0.0 2.6e-30 105.6 0.0 1.9 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3 HPS3_C PF14763.6 GAM23299.1 - 1.9e-05 24.2 0.8 0.00011 21.7 0.2 2.1 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3, C-terminal Sec1 PF00995.23 GAM23300.1 - 2.7e-70 238.2 4.9 2.7e-70 238.2 4.9 1.7 2 0 0 2 2 2 1 Sec1 family MAGE_N PF12440.8 GAM23300.1 - 3.3 8.4 6.3 27 5.5 0.6 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal HSP20 PF00011.21 GAM23301.1 - 3e-22 78.7 0.5 3.9e-22 78.3 0.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM23301.1 - 4e-07 29.5 0.0 6.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Ank_2 PF12796.7 GAM23302.1 - 1.4e-08 35.2 4.2 0.057 14.0 0.9 5.4 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM23302.1 - 0.00081 19.9 4.2 0.37 11.4 0.1 5.1 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM23302.1 - 0.0035 17.7 9.1 44 5.1 0.0 7.9 9 0 0 9 9 9 1 Ankyrin repeat Ribosomal_L13 PF00572.18 GAM23303.1 - 1e-11 45.2 0.1 1.2e-09 38.4 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 UPF0220 PF05255.11 GAM23304.1 - 3e-33 114.7 1.5 3.4e-33 114.5 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) MscL PF01741.18 GAM23304.1 - 0.0094 16.2 0.2 0.013 15.8 0.2 1.3 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL TMEM240 PF15207.6 GAM23304.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 TMEM240 family Lysine_decarbox PF03641.14 GAM23305.1 - 4.5e-42 143.3 0.0 5.6e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 GAM23305.1 - 6.2e-20 71.4 0.1 7.1e-20 71.2 0.1 1.1 1 0 0 1 1 1 1 SLOG cluster4 family DAGK_cat PF00781.24 GAM23305.1 - 0.057 13.0 0.3 7.5 6.2 0.1 2.2 1 1 1 2 2 2 0 Diacylglycerol kinase catalytic domain Amino_oxidase PF01593.24 GAM23306.1 - 1.3e-42 146.6 0.1 1.5e-41 143.2 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM23306.1 - 2.5e-08 34.0 0.0 6.5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAM23306.1 - 0.0081 15.5 0.3 0.014 14.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAM23306.1 - 0.024 15.2 0.1 0.049 14.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IF3_C PF00707.22 GAM23306.1 - 0.056 13.4 0.0 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain Pyr_redox_2 PF07992.14 GAM23306.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM23306.1 - 0.082 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPR_14 PF13428.6 GAM23307.1 - 4.9e-15 54.9 1.2 1.4e-05 25.5 0.2 4.6 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAM23307.1 - 6.6e-14 52.2 7.8 4.4e-06 27.1 0.8 3.2 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM23307.1 - 2e-13 49.7 3.6 0.00024 21.2 0.4 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM23307.1 - 3.6e-09 36.1 8.8 0.14 12.4 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM23307.1 - 3e-08 33.8 10.0 0.0003 21.0 0.3 4.0 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM23307.1 - 2.5e-07 30.3 9.2 0.15 12.3 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM23307.1 - 2.6e-07 31.2 1.2 0.023 15.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM23307.1 - 2.6e-05 23.9 2.7 2.3 8.4 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM23307.1 - 3.1e-05 23.3 3.4 0.027 13.7 0.9 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.6 GAM23307.1 - 0.00016 21.9 3.3 0.00023 21.5 1.8 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM23307.1 - 0.003 17.3 5.7 0.62 10.0 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAM23307.1 - 0.0052 16.8 2.1 0.095 12.7 0.9 2.9 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 ANAPC3 PF12895.7 GAM23307.1 - 0.0077 16.4 0.9 3.2 8.0 0.9 2.6 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 GAM23307.1 - 0.011 14.8 0.1 0.069 12.1 0.1 1.9 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.20 GAM23307.1 - 0.013 15.7 0.1 1.6 9.2 0.0 3.4 3 0 0 3 3 3 0 PPR repeat Sel1 PF08238.12 GAM23307.1 - 0.021 15.5 1.9 0.16 12.7 0.1 2.7 2 0 0 2 2 2 0 Sel1 repeat TPR_11 PF13414.6 GAM23307.1 - 0.047 13.4 0.2 0.047 13.4 0.2 3.1 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 GAM23307.1 - 0.071 13.3 1.0 0.35 11.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM23307.1 - 0.096 13.4 7.7 53 4.8 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3560 PF12083.8 GAM23307.1 - 0.19 11.9 5.4 5.5 7.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) TPR_10 PF13374.6 GAM23307.1 - 0.3 11.0 8.2 0.67 9.9 0.4 3.5 5 0 0 5 5 4 0 Tetratricopeptide repeat DEAD PF00270.29 GAM23308.1 - 1.1e-36 126.3 0.4 3e-36 124.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM23308.1 - 4.1e-23 81.8 0.0 1.5e-22 80.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM23308.1 - 1.7e-11 44.4 0.0 6.3e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAM23308.1 - 0.00016 21.4 0.2 0.0004 20.1 0.0 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 GAM23308.1 - 0.011 16.1 1.8 0.26 11.5 0.7 3.0 2 1 0 2 2 2 0 AAA domain NPAT_C PF15712.5 GAM23308.1 - 0.085 11.5 1.2 0.12 11.0 0.1 1.6 2 0 0 2 2 2 0 NPAT C terminus Kelch_6 PF13964.6 GAM23309.1 - 0.00041 20.5 2.3 0.094 13.0 0.3 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAM23309.1 - 0.0048 16.8 1.0 0.021 14.8 0.1 2.5 2 0 0 2 2 2 1 Kelch motif DUF1664 PF07889.12 GAM23309.1 - 0.01 15.9 2.2 0.01 15.9 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RPW8 PF05659.11 GAM23309.1 - 0.041 13.6 1.3 0.09 12.5 1.3 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Med15_fungi PF05397.12 GAM23309.1 - 0.16 12.2 3.6 0.51 10.6 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 15 LAGLIDADG_WhiA PF14527.6 GAM23309.1 - 0.19 11.8 1.4 2.7 8.1 0.0 2.3 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain Swm2 PF17083.5 GAM23309.1 - 0.25 11.4 6.4 0.32 11.0 3.7 2.2 2 1 0 2 2 2 0 Nucleolar protein Swm2 LOH1CR12 PF10158.9 GAM23309.1 - 0.34 10.9 4.6 0.19 11.8 1.5 2.1 2 0 0 2 2 2 0 Tumour suppressor protein Kelch_4 PF13418.6 GAM23310.1 - 0.00051 20.0 4.0 6.2 6.9 0.2 4.9 4 1 1 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM23310.1 - 0.00095 19.1 0.3 0.22 11.5 0.1 3.6 3 0 0 3 3 3 1 Kelch motif FlgN PF05130.12 GAM23310.1 - 0.017 15.7 0.9 1.1 9.8 1.9 2.2 2 0 0 2 2 2 0 FlgN protein DUF1664 PF07889.12 GAM23310.1 - 0.13 12.3 3.4 0.25 11.4 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Kelch_6 PF13964.6 GAM23310.1 - 0.19 12.1 6.1 0.25 11.7 0.2 3.8 3 1 1 4 4 4 0 Kelch motif Snapin_Pallidin PF14712.6 GAM23310.1 - 0.24 11.8 4.4 0.48 10.9 4.4 1.4 1 0 0 1 1 1 0 Snapin/Pallidin RPW8 PF05659.11 GAM23310.1 - 0.27 10.9 2.1 0.66 9.7 0.8 2.2 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Kelch_1 PF01344.25 GAM23310.1 - 0.43 10.2 1.7 3.9 7.1 0.0 3.2 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 GAM23311.1 - 0.015 15.3 6.9 2.6 8.1 0.0 5.2 6 0 0 6 6 6 0 Galactose oxidase, central domain Colicin_E5 PF12106.8 GAM23311.1 - 0.08 13.2 0.9 0.19 12.1 0.4 1.9 2 0 0 2 2 2 0 Colicin E5 ribonuclease domain Kelch_6 PF13964.6 GAM23311.1 - 0.082 13.2 5.2 36 4.9 0.0 4.8 4 1 1 5 5 5 0 Kelch motif CENP-Q PF13094.6 GAM23311.1 - 0.32 11.2 1.6 0.63 10.2 1.6 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit RPW8 PF05659.11 GAM23311.1 - 0.38 10.4 3.0 0.6 9.8 1.3 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PRESAN PF09687.10 GAM23311.1 - 1 9.9 8.6 0.22 12.1 4.1 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal DUF1664 PF07889.12 GAM23311.1 - 1.5 8.8 9.4 0.74 9.9 5.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 GAM23311.1 - 2.4 8.6 8.4 0.39 11.2 4.4 1.8 2 0 0 2 2 2 0 Snapin/Pallidin CEL_III_C PF18054.1 GAM23311.1 - 3.9 7.5 7.3 3.1 7.9 4.9 2.1 2 0 0 2 2 2 0 CEL-III C-terminal ILEI PF15711.5 GAM23312.1 - 4.1e-51 171.4 5.2 1.5e-13 51.0 0.0 4.4 4 0 0 4 4 4 4 Interleukin-like EMT inducer Peptidase_C14 PF00656.22 GAM23312.1 - 0.0092 16.0 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 Caspase domain CyRPA PF18638.1 GAM23312.1 - 0.088 11.9 0.8 0.15 11.2 0.8 1.3 1 0 0 1 1 1 0 Cysteine-Rich Protective Antigen 6 bladed domain KAP_NTPase PF07693.14 GAM23314.1 - 0.078 12.2 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Remorin_C PF03763.13 GAM23317.1 - 0.0038 17.1 0.1 0.0072 16.2 0.1 1.4 1 0 0 1 1 1 1 Remorin, C-terminal region IL3 PF02059.15 GAM23317.1 - 0.02 14.9 0.5 0.14 12.2 0.1 2.4 2 1 0 2 2 2 0 Interleukin-3 Stathmin PF00836.19 GAM23317.1 - 0.049 13.6 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Stathmin family TPR_1 PF00515.28 GAM23318.1 - 7.7e-32 107.8 9.9 1.5e-05 24.6 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAM23318.1 - 1.6e-27 93.4 5.0 0.00013 21.8 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAM23318.1 - 4.7e-18 64.6 9.9 1.8e-07 30.7 0.1 5.3 5 1 1 6 6 6 4 TPR repeat TPR_8 PF13181.6 GAM23318.1 - 2.3e-13 49.2 4.9 0.032 14.4 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM23318.1 - 1.7e-10 41.0 0.2 0.062 13.6 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM23318.1 - 1.7e-10 41.3 0.0 0.013 16.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM23318.1 - 3.8e-10 39.7 0.3 0.045 14.6 0.0 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM23318.1 - 1.1e-08 35.1 0.0 0.016 15.3 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM23318.1 - 3.7e-08 33.2 1.7 0.00091 19.4 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM23318.1 - 0.015 15.8 10.1 0.41 11.2 0.0 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat DXP_synthase_N PF13292.6 GAM23318.1 - 0.018 14.2 5.5 0.046 12.9 5.5 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF357 PF04010.13 GAM23318.1 - 0.093 12.8 0.2 12 6.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF357) DUF4175 PF13779.6 GAM23318.1 - 1.2 6.9 33.1 2.2 6.1 33.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 GAM23318.1 - 1.2 9.0 37.0 0.38 10.7 29.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 GAM23318.1 - 5.3 7.1 17.3 0.71 10.0 8.5 2.5 3 0 0 3 3 3 0 DDHD domain TERB2 PF15101.6 GAM23318.1 - 6 6.9 16.9 17 5.3 16.9 1.8 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pex14_N PF04695.13 GAM23318.1 - 6.2 7.5 26.8 1.9 9.1 16.6 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_19 PF14559.6 GAM23319.1 - 0.0015 19.0 5.3 4.9 7.7 0.1 5.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM23319.1 - 0.011 15.8 5.4 0.03 14.4 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM23319.1 - 0.011 16.3 1.7 0.43 11.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 GAM23320.1 - 4.7e-16 58.9 13.9 0.00035 21.3 2.5 6.9 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM23320.1 - 0.00037 20.7 0.1 2.7 8.4 0.0 3.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAM23320.1 - 0.052 12.1 0.0 2 6.9 0.0 2.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain PQQ PF01011.21 GAM23320.1 - 0.1 12.6 0.4 31 4.7 0.0 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat Ric8 PF10165.9 GAM23321.1 - 8.9e-23 81.0 0.1 2.8e-22 79.4 0.1 1.7 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Bot1p PF12298.8 GAM23322.1 - 1.7e-07 31.6 0.0 2.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-S22 PF10245.9 GAM23322.1 - 0.021 14.6 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 DGCR6 PF07324.11 GAM23323.1 - 1.3e-09 37.9 3.6 1.3e-09 37.9 3.6 1.7 2 0 0 2 2 2 1 DiGeorge syndrome critical region 6 (DGCR6) protein SR-25 PF10500.9 GAM23323.1 - 9.8e-05 22.1 6.9 9.8e-05 22.1 6.9 2.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein NARP1 PF12569.8 GAM23323.1 - 5.1 5.9 13.5 6.9 5.4 7.2 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Pkinase_Tyr PF07714.17 GAM23324.1 - 3.6e-56 190.3 0.0 5.6e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM23324.1 - 1.3e-52 178.8 0.0 2.6e-52 177.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAM23324.1 - 0.00022 20.2 2.1 0.0012 17.7 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM23324.1 - 0.00024 20.1 0.2 0.00024 20.1 0.2 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 GAM23324.1 - 0.018 14.3 0.3 0.05 12.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 GAM23324.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 GAM23324.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.13 GAM23324.1 - 0.48 10.4 14.6 0.67 9.9 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.12 GAM23324.1 - 3.4 5.5 5.4 4.7 5.1 5.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein His_Phos_1 PF00300.22 GAM23325.1 - 4.8e-22 78.6 0.0 5.7e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1517 PF07466.11 GAM23325.1 - 0.053 13.6 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) RVT_1 PF00078.27 GAM23326.1 - 1.6e-40 138.9 0.0 2.8e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GAM23326.1 - 0.026 14.1 0.4 0.058 12.9 0.4 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family SHMT PF00464.19 GAM23327.1 - 0.0065 15.1 0.1 0.0089 14.7 0.1 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Ribosomal_S3Ae PF01015.18 GAM23327.1 - 0.03 13.9 0.6 0.059 12.9 0.6 1.4 1 0 0 1 1 1 0 Ribosomal S3Ae family DUF4504 PF14953.6 GAM23328.1 - 8.6e-20 71.2 2.9 1.1e-19 70.8 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) DUF5332 PF17266.2 GAM23328.1 - 0.026 14.2 6.7 0.12 12.1 6.7 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5332) DUF4646 PF15496.6 GAM23328.1 - 0.083 13.5 0.0 2.6 8.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) DUF3472 PF11958.8 GAM23329.1 - 3.2e-10 40.8 0.4 3.2e-10 40.8 0.4 2.3 3 1 0 3 3 3 1 Domain of unknown function (DUF3472) RicinB_lectin_2 PF14200.6 GAM23329.1 - 0.015 16.0 3.2 0.015 16.0 3.2 4.7 3 1 2 5 5 5 0 Ricin-type beta-trefoil lectin domain-like YbfN PF13982.6 GAM23329.1 - 0.042 14.1 2.8 0.61 10.4 0.5 2.3 2 0 0 2 2 2 0 YbfN-like lipoprotein GPI-anchored PF10342.9 GAM23329.1 - 0.043 14.6 0.8 0.043 14.6 0.8 2.9 2 1 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Kelch_6 PF13964.6 GAM23331.1 - 1.2e-08 34.9 2.8 0.0061 16.8 0.1 4.1 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAM23331.1 - 0.012 15.5 0.0 0.08 12.9 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.6 GAM23331.1 - 0.045 13.8 1.9 0.79 9.8 0.0 3.6 5 0 0 5 5 5 0 Galactose oxidase, central domain PQ-loop PF04193.14 GAM23332.1 - 1.3e-24 85.7 13.1 2.1e-13 49.8 2.1 2.6 2 0 0 2 2 2 2 PQ loop repeat HEAT_EZ PF13513.6 GAM23333.1 - 5.8e-37 125.7 9.9 5.4e-17 61.9 0.0 10.8 11 0 0 11 11 11 4 HEAT-like repeat HEAT PF02985.22 GAM23333.1 - 3e-31 104.8 11.8 0.0001 22.2 0.0 11.3 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 GAM23333.1 - 5.7e-23 81.1 0.0 8.2e-06 26.1 0.0 6.8 5 2 2 7 7 7 5 HEAT repeats Cnd1 PF12717.7 GAM23333.1 - 3.6e-17 62.9 4.8 2e-06 27.9 0.0 5.5 4 2 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAM23333.1 - 9.8e-13 47.7 2.5 0.072 13.2 0.0 6.8 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 GAM23333.1 - 3.2e-11 43.0 2.8 5e-10 39.2 0.1 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 GAM23333.1 - 2.8e-10 40.7 0.2 0.11 13.1 0.0 6.9 5 2 4 9 9 9 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 GAM23333.1 - 2.5e-07 29.6 13.6 7.4e-05 21.5 0.9 4.6 4 2 0 4 4 4 2 Adaptin N terminal region MMS19_C PF12460.8 GAM23333.1 - 0.00029 20.1 0.9 0.00029 20.1 0.9 3.9 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal UME PF08064.13 GAM23333.1 - 0.00036 20.4 2.2 0.53 10.2 0.0 4.5 4 1 1 5 5 4 1 UME (NUC010) domain Tti2 PF10521.9 GAM23333.1 - 0.00042 19.9 3.2 1.9 8.0 0.1 4.7 2 1 2 4 4 4 2 Tti2 family DUF3385 PF11865.8 GAM23333.1 - 0.0007 19.5 5.2 0.066 13.1 0.0 5.3 4 2 1 5 5 5 1 Domain of unknown function (DUF3385) Xpo1 PF08389.12 GAM23333.1 - 0.0059 16.7 4.5 0.19 11.8 0.1 4.4 4 1 1 5 5 5 1 Exportin 1-like protein DUF3437 PF11919.8 GAM23333.1 - 0.016 15.1 0.8 2.4 8.1 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) MMS19_N PF14500.6 GAM23333.1 - 0.018 14.6 0.2 6.9 6.2 0.0 3.6 3 2 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_PBS PF03130.16 GAM23333.1 - 0.019 15.6 0.0 0.66 10.8 0.0 3.7 4 0 0 4 4 2 0 PBS lyase HEAT-like repeat DUF3689 PF12463.8 GAM23333.1 - 0.024 14.0 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) RTP1_C1 PF10363.9 GAM23333.1 - 0.088 13.0 3.2 22 5.3 0.0 4.6 4 2 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 BK_channel_a PF03493.18 GAM23334.1 - 5.9e-22 77.7 0.5 1.8e-20 73.0 0.0 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 GAM23334.1 - 4.6e-14 52.1 3.9 9.8e-14 51.1 3.9 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 GAM23334.1 - 7.6e-08 31.9 19.7 1.3e-07 31.1 15.4 2.7 2 1 0 2 2 2 1 Ion transport protein TrkA_N PF02254.18 GAM23334.1 - 0.00012 22.3 0.0 0.029 14.6 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain Castor_Poll_mid PF06241.12 GAM23334.1 - 0.0005 20.0 0.2 0.028 14.4 0.1 3.2 2 1 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel Sclerostin PF05463.11 GAM23334.1 - 2.5 7.8 5.2 4.7 6.9 0.1 2.3 2 0 0 2 2 2 0 Sclerostin (SOST) DUF3592 PF12158.8 GAM23335.1 - 0.0034 17.5 4.5 0.032 14.3 4.5 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3592) UL20 PF17582.2 GAM23335.1 - 0.02 14.2 0.0 0.02 14.2 0.0 2.1 2 0 0 2 2 2 0 Cytomegalovirus UL20 Dicty_REP PF05086.12 GAM23336.1 - 0.012 13.7 5.5 0.014 13.5 5.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF778 PF05608.12 GAM23336.1 - 0.051 13.9 0.0 0.16 12.3 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF778) DUF3439 PF11921.8 GAM23336.1 - 0.55 10.2 10.6 1 9.4 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAM23336.1 - 1.7 8.6 12.9 2.8 7.9 12.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase PF00069.25 GAM23337.1 - 7.8e-43 146.7 0.0 7.8e-43 146.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM23337.1 - 1.5e-19 70.3 0.0 1.5e-19 70.3 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase DUF1081 PF06448.11 GAM23337.1 - 0.087 13.2 8.7 0.23 11.9 8.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) TFIIA PF03153.13 GAM23337.1 - 1.8 8.4 37.2 3.6 7.5 37.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 GAM23337.1 - 5.7 6.4 18.3 12 5.4 18.3 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RabGAP-TBC PF00566.18 GAM23338.1 - 5.2e-44 150.5 0.1 5.2e-44 150.5 0.1 2.6 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF4337 PF14235.6 GAM23338.1 - 0.41 10.8 4.0 0.64 10.1 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2951 PF11166.8 GAM23338.1 - 2.1 8.6 8.3 5.4 7.3 8.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) WD40 PF00400.32 GAM23339.1 - 4.4e-34 116.0 10.9 2.9e-06 27.9 0.2 6.8 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM23339.1 - 6.5e-17 61.6 0.0 3.6e-07 30.4 0.0 5.3 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 GAM23339.1 - 6.2e-12 44.9 0.2 1.2e-11 44.1 0.2 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 GAM23339.1 - 5.8e-10 38.6 0.8 5.3e-05 22.3 0.0 3.8 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAM23339.1 - 1.8e-09 36.8 0.5 0.85 8.2 0.3 4.9 1 1 2 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 GAM23339.1 - 0.00034 20.0 0.1 0.0006 19.2 0.1 1.4 1 0 0 1 1 1 1 WD40-like domain Hira PF07569.11 GAM23339.1 - 0.0071 16.1 0.4 2.3 7.9 0.1 3.8 4 1 0 4 4 4 1 TUP1-like enhancer of split Nucleoporin_N PF08801.11 GAM23339.1 - 0.02 13.7 0.6 1.4 7.6 0.0 3.0 1 1 1 3 3 3 0 Nup133 N terminal like PALB2_WD40 PF16756.5 GAM23339.1 - 0.066 12.1 0.0 1.3 7.8 0.0 2.7 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain EF-hand_1 PF00036.32 GAM23340.1 - 5.7e-24 81.8 8.2 7.1e-06 25.2 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 GAM23340.1 - 7.6e-24 81.6 2.5 2.4e-06 27.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 GAM23340.1 - 6.9e-21 74.5 6.2 1.9e-10 41.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM23340.1 - 2.6e-19 67.8 9.5 3.1e-05 23.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAM23340.1 - 1.1e-13 50.8 0.4 0.026 14.4 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM23340.1 - 3.1e-06 27.5 0.3 0.24 11.7 0.0 3.2 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GAM23340.1 - 0.00019 21.7 0.2 0.016 15.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 GAM23340.1 - 0.0046 16.9 4.4 0.041 13.8 0.2 3.2 2 2 2 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 GAM23340.1 - 0.044 13.7 4.2 9.6 6.2 0.0 4.0 4 0 0 4 4 4 0 EF hand EGF_2 PF07974.13 GAM23341.1 - 0.0011 19.3 13.6 0.0021 18.4 13.6 1.5 1 0 0 1 1 1 1 EGF-like domain RasGEF PF00617.19 GAM23342.1 - 6.1e-62 208.9 0.2 1.5e-61 207.6 0.2 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM23342.1 - 4.9e-26 91.0 0.5 4.9e-26 91.0 0.5 3.9 4 0 0 4 4 4 1 RasGEF N-terminal motif TFIIA PF03153.13 GAM23342.1 - 0.63 10.0 42.7 1.2 9.0 42.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP_M PF14637.6 GAM23343.1 - 5.9e-54 183.5 0.2 1.6e-53 182.0 0.0 1.9 2 0 0 2 2 2 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 GAM23343.1 - 1.2e-18 67.4 0.1 7.7e-18 64.8 0.0 2.2 2 0 0 2 2 2 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 GAM23343.1 - 1.7e-09 38.9 4.6 1.7e-09 38.9 4.6 4.0 3 2 1 4 4 4 2 Folliculin-interacting protein N-terminus Longin_2 PF18639.1 GAM23343.1 - 0.022 14.6 0.1 0.055 13.3 0.1 1.6 1 1 0 1 1 1 0 Yeast longin domain MecA PF05389.12 GAM23343.1 - 0.84 9.2 8.9 4 7.0 3.0 2.4 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Spt20 PF12090.8 GAM23343.1 - 1.1 8.9 29.9 0.017 14.7 13.5 2.6 2 0 0 2 2 2 0 Spt20 family DUF4484 PF14831.6 GAM23343.1 - 1.3 9.1 6.5 1.8 8.6 1.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4484) Suf PF05843.14 GAM23343.1 - 1.4 8.8 23.0 0.6 10.0 4.8 2.9 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) DUF3464 PF11947.8 GAM23343.1 - 1.6 8.4 8.0 0.11 12.3 0.7 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 TFIIA PF03153.13 GAM23343.1 - 4.5 7.2 31.8 1 9.3 16.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Stevor PF17410.2 GAM23344.1 - 0.0025 17.4 0.1 0.0052 16.4 0.1 1.5 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame EGF_2 PF07974.13 GAM23344.1 - 0.058 13.8 14.5 0.12 12.8 14.5 1.6 1 0 0 1 1 1 0 EGF-like domain SKG6 PF08693.10 GAM23344.1 - 0.16 11.4 7.1 0.33 10.4 7.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF PF00008.27 GAM23344.1 - 7.9 6.9 10.3 21 5.6 10.3 1.7 1 0 0 1 1 1 0 EGF-like domain DUF4448 PF14610.6 GAM23345.1 - 0.028 14.2 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EGF_2 PF07974.13 GAM23345.1 - 5.1 7.6 15.6 11 6.5 15.6 1.6 1 0 0 1 1 1 0 EGF-like domain Glyco_transf_10 PF00852.19 GAM23346.1 - 1.4e-35 122.6 1.3 1.4e-35 122.6 1.3 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 GAM23346.1 - 8.4e-07 29.4 1.5 1.8e-06 28.4 0.2 2.1 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Ribosomal_L34e PF01199.18 GAM23347.1 - 2.1e-41 140.1 5.7 2.1e-41 140.1 5.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L34e Zn-ribbon_8 PF09723.10 GAM23347.1 - 0.019 15.1 1.0 0.046 13.8 0.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 GAM23347.1 - 0.059 13.4 1.0 5.1 7.2 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbons Nkap_C PF06047.11 GAM23347.1 - 0.066 13.3 0.8 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain SKIP_SNW PF02731.15 GAM23348.1 - 5.1e-67 224.5 6.2 5.1e-67 224.5 6.2 2.6 3 0 0 3 3 3 1 SKIP/SNW domain EF-hand_1 PF00036.32 GAM23349.1 - 2.5e-22 76.7 9.0 6.1e-08 31.7 0.1 5.1 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 GAM23349.1 - 7.1e-19 68.0 2.5 3.9e-10 40.0 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM23349.1 - 1.4e-18 65.1 6.7 1.5e-07 30.8 0.1 5.7 4 2 2 6 6 6 4 EF-hand domain EF-hand_9 PF14658.6 GAM23349.1 - 1.5e-11 44.5 0.2 5.6e-08 33.0 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAM23349.1 - 3.4e-10 39.6 9.3 6.7e-05 22.7 0.2 4.9 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 GAM23349.1 - 9.7e-10 37.5 6.4 7.6e-06 25.2 0.2 4.8 5 0 0 5 5 5 2 EF hand EF-hand_14 PF17959.1 GAM23349.1 - 0.0051 17.1 0.7 0.3 11.4 0.6 2.7 1 1 0 1 1 1 1 EF-hand domain Caleosin PF05042.13 GAM23349.1 - 0.043 13.7 0.1 0.46 10.4 0.0 2.3 2 1 1 3 3 3 0 Caleosin related protein Aminotran_5 PF00266.19 GAM23350.1 - 2.3e-49 168.3 0.0 2.7e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V SWIRM PF04433.17 GAM23352.1 - 5.2e-26 90.8 0.2 1.4e-25 89.5 0.2 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 GAM23352.1 - 2.6e-13 49.7 2.9 2.6e-13 49.7 2.9 1.9 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 GAM23352.1 - 3.1e-09 36.9 0.0 5.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM23352.1 - 1.6e-05 25.0 0.3 3.8e-05 23.8 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM23352.1 - 0.085 12.8 0.9 0.24 11.3 0.1 2.2 2 0 0 2 2 2 0 Myb DNA-binding like Mucin PF01456.17 GAM23352.1 - 0.2 11.6 39.5 0.034 14.1 10.9 2.6 3 0 0 3 3 3 0 Mucin-like glycoprotein Pex14_N PF04695.13 GAM23352.1 - 6.7 7.3 22.2 0.14 12.8 9.8 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3439 PF11921.8 GAM23352.1 - 6.8 6.7 34.7 0.096 12.7 10.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) KH_6 PF15985.5 GAM23353.1 - 3.1e-11 43.4 0.1 5.3e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 GAM23353.1 - 0.00018 21.4 0.0 0.00054 19.8 0.0 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain AIDA PF16168.5 GAM23353.1 - 0.074 13.1 0.6 0.18 11.9 0.2 1.9 2 0 0 2 2 2 0 Adhesin of bacterial autotransporter system, probable stalk DUF2505 PF10698.9 GAM23354.1 - 0.00014 22.0 0.0 0.00033 20.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2505) PRELI PF04707.14 GAM23354.1 - 0.098 12.5 0.3 0.15 11.9 0.3 1.3 1 0 0 1 1 1 0 PRELI-like family FtsJ PF01728.19 GAM23355.1 - 1.7e-48 165.1 0.0 2.1e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 GAM23355.1 - 0.00018 21.3 0.0 0.0016 18.3 0.0 2.1 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GAM23355.1 - 0.023 14.5 0.0 0.27 11.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 GAM23355.1 - 0.027 14.1 0.0 0.87 9.2 0.0 2.7 3 0 0 3 3 3 0 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 GAM23355.1 - 0.038 13.3 0.0 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAM23355.1 - 0.14 12.9 0.1 0.67 10.7 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain LMBR1 PF04791.16 GAM23356.1 - 1.5e-72 245.2 40.7 1.3e-51 176.1 14.5 2.6 2 1 1 3 3 3 2 LMBR1-like membrane protein DBB PF14545.6 GAM23356.1 - 0.073 13.0 0.2 0.77 9.7 0.0 2.3 2 0 0 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, RRM_1 PF00076.22 GAM23358.1 - 1.2e-05 25.1 0.2 8.3e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Muted PF14942.6 GAM23358.1 - 0.68 10.3 8.9 0.63 10.4 7.0 1.8 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein RNA_ligase PF09414.10 GAM23359.1 - 1.3e-18 67.8 0.0 2e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 RNA ligase GlcNAc PF11397.8 GAM23360.1 - 3.5e-89 299.7 0.0 2.3e-76 257.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) SR-25 PF10500.9 GAM23360.1 - 0.21 11.2 2.1 0.32 10.6 2.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RE_TaqI PF09573.10 GAM23361.1 - 0.013 15.3 0.3 0.014 15.2 0.3 1.2 1 0 0 1 1 1 0 TaqI restriction endonuclease DUF5448 PF17526.2 GAM23361.1 - 0.022 14.9 0.6 0.029 14.5 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5448) Uds1 PF15456.6 GAM23361.1 - 0.94 9.6 7.4 5.6 7.1 7.4 1.9 1 1 0 1 1 1 0 Up-regulated During Septation RhoGEF PF00621.20 GAM23362.1 - 6.1e-44 150.4 4.4 2.3e-43 148.5 4.4 2.1 1 0 0 1 1 1 1 RhoGEF domain PX PF00787.24 GAM23362.1 - 9.2e-19 67.5 1.9 1.8e-18 66.6 0.7 2.2 2 0 0 2 2 2 1 PX domain CH PF00307.31 GAM23362.1 - 0.094 12.9 2.5 0.36 11.0 0.1 3.3 4 0 0 4 4 4 0 Calponin homology (CH) domain COMPASS-Shg1 PF05205.12 GAM23362.1 - 7.1 7.4 9.3 14 6.5 0.8 3.2 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 Big_1 PF02369.16 GAM23363.1 - 1.4 9.0 12.0 4.2 7.4 4.8 3.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Bact_lectin PF18483.1 GAM23364.1 - 5.2e-21 75.6 0.1 5.2e-21 75.6 0.1 1.6 2 0 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 GAM23364.1 - 1.6e-18 67.1 0.2 5.5e-18 65.4 0.0 1.8 2 0 0 2 2 2 1 Legume lectin domain DUF3439 PF11921.8 GAM23364.1 - 0.0036 17.3 3.3 0.0083 16.1 3.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.11 GAM23364.1 - 0.95 7.6 5.0 1.3 7.1 5.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Methyltransf_25 PF13649.6 GAM23365.1 - 4.2e-10 40.2 0.0 1.4e-09 38.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM23365.1 - 8.5e-10 38.6 0.0 1.6e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAM23365.1 - 1.6e-09 37.6 0.1 2.5e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAM23365.1 - 6.6e-08 33.1 0.0 2.3e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAM23365.1 - 1.9e-07 30.3 0.1 2.5e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 GAM23365.1 - 9.7e-07 28.8 0.0 4.8e-06 26.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 GAM23365.1 - 8.3e-05 22.5 0.0 0.00019 21.4 0.0 1.7 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.14 GAM23365.1 - 0.00017 21.2 0.1 0.00027 20.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAM23365.1 - 0.00053 20.7 0.0 0.0013 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAM23365.1 - 0.0019 18.0 0.1 0.0032 17.2 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase CMAS PF02353.20 GAM23365.1 - 0.0038 16.5 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 GAM23365.1 - 0.0045 16.9 0.1 0.0078 16.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 GAM23365.1 - 0.01 15.3 0.3 0.78 9.1 0.2 2.7 2 1 0 2 2 2 0 Tellurite resistance protein TehB PCMT PF01135.19 GAM23365.1 - 0.023 14.5 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UBX PF00789.20 GAM23366.1 - 7e-15 55.0 0.0 1.4e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Ubiquitin_2 PF14560.6 GAM23366.1 - 0.0066 16.9 0.1 0.38 11.2 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 GAM23366.1 - 0.0082 15.9 3.9 0.013 15.2 0.0 3.2 4 0 0 4 4 4 1 Ubiquitin family Thioredoxin_7 PF13899.6 GAM23366.1 - 0.0093 16.1 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like GCD14 PF08704.10 GAM23366.1 - 2.2 7.9 13.6 0.037 13.7 3.8 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Na_trans_assoc PF06512.13 GAM23366.1 - 4.2 7.6 13.0 4.2 7.6 0.8 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated IPPT PF01715.17 GAM23367.1 - 3.4e-54 184.1 5.4 1.3e-53 182.2 5.4 1.9 1 1 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.8 GAM23367.1 - 3e-07 30.6 2.2 6.3e-07 29.5 2.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM23367.1 - 5.6e-06 26.6 1.5 1.2e-05 25.5 1.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type IPT PF01745.16 GAM23367.1 - 1.9e-05 24.1 0.0 4.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase AAA_18 PF13238.6 GAM23367.1 - 0.0004 20.9 6.3 0.0033 18.0 0.0 3.2 3 1 0 3 3 3 1 AAA domain Hpr_kinase_C PF07475.12 GAM23367.1 - 0.00048 19.7 2.4 0.00092 18.8 0.2 2.2 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain AAA_33 PF13671.6 GAM23367.1 - 0.0014 18.8 3.1 0.0051 17.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 GAM23367.1 - 0.004 17.5 0.1 0.038 14.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase HARP PF07443.13 GAM23367.1 - 0.012 15.2 0.2 0.029 14.0 0.2 1.5 1 0 0 1 1 1 0 HepA-related protein (HARP) AAA_16 PF13191.6 GAM23367.1 - 0.036 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAM23367.1 - 0.042 14.1 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 GAM23367.1 - 0.046 13.6 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 IstB_IS21 PF01695.17 GAM23367.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 GAM23367.1 - 0.11 12.9 0.9 0.49 10.8 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 GAM23367.1 - 0.22 11.8 0.1 0.22 11.8 0.1 3.4 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain ABC_tran PF00005.27 GAM23367.1 - 0.39 11.2 0.0 0.39 11.2 0.0 2.5 2 1 0 2 2 1 0 ABC transporter DUF3439 PF11921.8 GAM23367.1 - 1.8 8.5 12.7 3.9 7.4 12.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ribosomal_S11 PF00411.19 GAM23368.1 - 7.9e-33 113.1 0.2 1.1e-32 112.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L18p PF00861.22 GAM23368.1 - 0.1 13.0 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Phage_glycop_gL PF11108.8 GAM23369.1 - 0.074 13.1 0.0 0.074 13.1 0.0 1.2 1 0 0 1 1 1 0 Viral glycoprotein L Glyco_hydro_18 PF00704.28 GAM23370.1 - 0.0017 18.2 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 7tm_3 PF00003.22 GAM23371.1 - 6.1e-37 127.6 28.5 6.1e-37 127.6 28.5 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 GAM23371.1 - 1.2e-14 54.0 0.5 1.8e-14 53.4 0.5 1.1 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Claudin_2 PF13903.6 GAM23371.1 - 0.0014 18.4 2.1 0.0014 18.4 2.1 3.4 2 1 1 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction Rax2 PF12768.7 GAM23371.1 - 0.049 13.1 1.5 0.22 10.9 1.5 2.1 1 1 0 1 1 1 0 Cortical protein marker for cell polarity MAP17 PF15807.5 GAM23371.1 - 6.5 7.0 6.7 0.33 11.2 0.5 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4460 PF14687.6 GAM23372.1 - 3.2e-05 24.0 0.1 3.2e-05 24.0 0.1 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4460) TraV PF09676.10 GAM23372.1 - 1.6 9.7 13.5 5.5 8.0 4.2 3.1 3 0 0 3 3 3 0 Type IV conjugative transfer system lipoprotein (TraV) RR_TM4-6 PF06459.12 GAM23372.1 - 3.8 7.3 16.6 5.3 6.8 1.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TP53IP5 PF15331.6 GAM23372.1 - 4.9 7.2 14.9 5.5 7.1 2.1 2.4 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Spt20 PF12090.8 GAM23372.1 - 5.9 6.4 26.5 0.73 9.4 6.0 2.5 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 GAM23372.1 - 7.4 5.2 15.4 3.4 6.3 1.3 2.2 2 0 0 2 2 2 0 Presenilin DUF2572 PF10833.8 GAM23373.1 - 1.1 9.0 7.6 1.9 8.2 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) WD40 PF00400.32 GAM23375.1 - 1.4e-11 44.7 0.9 0.0018 19.1 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40_like PF17005.5 GAM23375.1 - 0.00015 21.3 5.3 0.02 14.3 2.5 2.3 1 1 1 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 GAM23375.1 - 0.00066 19.9 0.1 0.072 13.4 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 GAM23376.1 - 3.3e-53 180.8 0.0 8.4e-53 179.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM23376.1 - 1.1e-37 129.8 0.0 2.5e-37 128.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.27 GAM23376.1 - 5.6e-31 107.4 0.2 1.6e-30 105.9 0.2 1.8 1 0 0 1 1 1 1 RhoGAP domain Kinase-like PF14531.6 GAM23376.1 - 0.00042 19.7 0.0 0.00095 18.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 GAM23376.1 - 0.0013 19.2 0.4 0.0088 16.5 0.0 2.5 2 1 0 2 2 2 1 PH domain ABC_tran_Xtn PF12848.7 GAM23376.1 - 0.02 14.9 3.4 0.056 13.5 3.4 1.7 1 0 0 1 1 1 0 ABC transporter FTA2 PF13095.6 GAM23376.1 - 0.11 12.1 0.5 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 GAM23377.1 - 4.7e-16 58.4 0.1 7.1e-16 57.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAM23377.1 - 0.029 14.5 0.1 0.053 13.6 0.1 1.3 1 0 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.6 GAM23377.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Myb_DNA-binding PF00249.31 GAM23378.1 - 2e-32 111.1 12.3 1.2e-14 54.2 0.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM23378.1 - 6.8e-29 99.9 2.8 5.5e-15 55.4 0.2 3.5 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 GAM23378.1 - 0.00049 20.1 4.5 0.32 11.0 0.1 2.6 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 GAM23378.1 - 0.22 11.7 8.7 7.6 6.8 1.4 3.3 1 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 DUF4588 PF15251.6 GAM23378.1 - 1.4 8.6 9.0 0.14 11.9 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) FNIP PF05725.12 GAM23379.1 - 3.6e-61 203.1 12.6 1.9e-16 60.0 0.1 7.4 7 1 0 7 7 7 6 FNIP Repeat Phage_min_tail PF05939.13 GAM23379.1 - 0.23 11.9 0.0 1.2 9.5 0.0 2.0 1 1 1 2 2 2 0 Phage minor tail protein LPMO_10 PF03067.15 GAM23380.1 - 7.2e-26 92.0 0.2 7.2e-26 92.0 0.2 2.2 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading GMC_oxred_N PF00732.19 GAM23381.1 - 9.8e-45 153.2 0.1 1.7e-44 152.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM23381.1 - 1.3e-20 74.4 0.4 4e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 GAM23381.1 - 1.9e-06 27.8 0.0 4.3e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM23381.1 - 6.5e-06 25.5 0.5 0.00011 21.4 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAM23381.1 - 2.5e-05 24.4 0.2 7.5e-05 22.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAM23381.1 - 0.00024 20.5 0.7 0.00038 19.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAM23381.1 - 0.0017 17.7 0.2 0.0036 16.6 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAM23381.1 - 0.0026 17.1 0.1 0.01 15.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM23381.1 - 0.023 13.4 1.7 0.048 12.4 1.7 1.5 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 GAM23381.1 - 0.035 13.2 0.1 0.075 12.1 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 GAM23381.1 - 0.082 12.5 2.0 0.16 11.6 2.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 GAM23381.1 - 0.14 11.4 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM23381.1 - 0.95 8.7 3.5 1.7 7.9 3.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Mito_carr PF00153.27 GAM23382.1 - 7.4e-67 221.3 5.5 4.6e-22 77.8 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAM23382.1 - 0.0027 16.9 0.6 0.73 8.9 0.0 2.8 3 1 0 3 3 3 2 Gammaproteobacterial serine protease Cyt-b5 PF00173.28 GAM23384.1 - 8.2e-19 67.5 0.2 1.2e-18 67.1 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Aph-1 PF06105.12 GAM23385.1 - 7.3e-69 231.7 15.2 8.9e-69 231.4 15.2 1.0 1 0 0 1 1 1 1 Aph-1 protein MRP-S25 PF13741.6 GAM23385.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 FYVE PF01363.21 GAM23386.1 - 1.5e-19 69.8 8.8 3.2e-19 68.8 8.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.23 GAM23386.1 - 2.3e-13 49.7 2.6 0.015 15.3 0.0 5.7 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat FYVE_2 PF02318.16 GAM23386.1 - 0.0087 16.3 6.9 0.022 14.9 6.9 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger STAG PF08514.11 GAM23386.1 - 0.01 15.7 0.1 0.038 13.9 0.1 1.9 1 1 1 2 2 2 0 STAG domain Arm_2 PF04826.13 GAM23386.1 - 0.02 14.4 16.6 1.1 8.6 0.1 3.9 1 1 2 3 3 3 0 Armadillo-like DZR PF12773.7 GAM23386.1 - 0.88 9.6 8.9 4.4 7.4 1.3 2.7 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.6 GAM23386.1 - 9.2 6.3 14.6 27 4.8 14.6 1.8 1 1 0 1 1 1 0 zinc-RING finger domain GTP_EFTU PF00009.27 GAM23387.1 - 1.9e-55 187.4 0.0 2.8e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM23387.1 - 1.6e-37 128.2 0.3 7.1e-37 126.1 0.0 2.2 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAM23387.1 - 9.9e-15 54.7 0.3 2.6e-14 53.4 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM23387.1 - 3.8e-05 23.7 0.1 0.00091 19.3 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GAM23387.1 - 0.02 14.8 1.0 0.046 13.6 0.2 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 tRNA-synt_1b PF00579.25 GAM23388.1 - 3.8e-21 75.7 0.0 2e-20 73.3 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) Dus PF01207.17 GAM23390.1 - 3.7e-54 183.9 0.0 6.2e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 GAM23390.1 - 2.4e-09 36.9 9.5 3e-07 30.2 0.2 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAM23390.1 - 5.5e-07 29.4 10.6 3.9e-05 23.6 0.7 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GAM23390.1 - 9.1e-07 28.5 7.3 3.5e-05 23.5 0.8 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 GAM23390.1 - 0.084 13.4 3.8 1.7 9.2 0.5 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger adh_short PF00106.25 GAM23391.1 - 1.8e-12 47.1 0.0 2.6e-10 40.1 0.1 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAM23391.1 - 3.2e-08 33.4 0.0 2.7e-07 30.4 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase FNIP PF05725.12 GAM23392.1 - 4.6e-43 145.1 16.1 9.4e-14 51.3 1.1 5.6 3 2 2 5 5 5 5 FNIP Repeat VRR_NUC PF08774.11 GAM23393.1 - 1.6e-20 73.2 0.0 3.5e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain PAP1 PF08601.10 GAM23393.1 - 1.7 8.3 18.4 3 7.5 18.4 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Ecl1 PF12855.7 GAM23393.1 - 4.5 8.4 19.0 9.2 7.4 19.0 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Thioredoxin PF00085.20 GAM23394.1 - 5.1e-33 113.2 0.1 1.6e-15 56.9 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 GAM23394.1 - 2.1e-10 40.8 0.3 1.3e-07 31.7 0.0 3.9 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 GAM23394.1 - 2.3e-06 28.0 2.7 0.067 13.7 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAM23394.1 - 0.0004 20.5 0.1 0.73 10.1 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 GAM23394.1 - 0.002 18.4 0.3 3.5 8.0 0.0 3.8 2 1 1 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 GAM23394.1 - 0.0051 16.7 0.1 0.97 9.4 0.0 2.8 2 1 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 GAM23394.1 - 0.0076 16.0 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 Redoxin Glutaredoxin PF00462.24 GAM23394.1 - 0.14 12.4 1.9 24 5.2 0.9 2.9 2 1 0 2 2 2 0 Glutaredoxin Peptidase_S49_N PF08496.10 GAM23394.1 - 1.1 9.3 5.2 0.91 9.6 3.4 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal O-antigen_lig PF13425.6 GAM23394.1 - 1.8 7.3 4.4 2.7 6.7 4.4 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein UPF0172 PF03665.13 GAM23394.1 - 1.8 8.6 5.0 1.6 8.7 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) SprA-related PF12118.8 GAM23394.1 - 5.3 6.1 12.2 10 5.1 12.2 1.4 1 0 0 1 1 1 0 SprA-related family Glyco_hydro_47 PF01532.20 GAM23395.1 - 2.8e-110 369.3 1.4 4e-110 368.9 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4419 PF14388.6 GAM23396.1 - 1.5e-82 277.4 0.3 1.9e-82 277.1 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) SepSecS PF05889.13 GAM23397.1 - 4.9e-128 427.1 0.0 5.9e-128 426.9 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 GAM23397.1 - 0.0069 15.7 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase zf-RING_2 PF13639.6 GAM23398.1 - 7e-13 48.7 7.1 1e-12 48.1 7.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAM23398.1 - 5.3e-09 35.7 3.8 1e-08 34.7 3.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAM23398.1 - 3.1e-07 30.1 8.3 4.8e-07 29.5 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM23398.1 - 6.5e-07 29.5 9.5 2.6e-06 27.6 9.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAM23398.1 - 3e-06 27.0 3.7 4.6e-06 26.4 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM23398.1 - 3.8e-06 26.7 8.7 6.8e-06 25.9 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM23398.1 - 5.1e-05 23.2 5.6 9e-05 22.4 5.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAM23398.1 - 8.4e-05 22.5 1.0 0.00013 22.0 1.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 GAM23398.1 - 0.00082 19.0 3.2 0.0014 18.2 3.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAM23398.1 - 0.0018 18.2 5.5 0.0032 17.4 5.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAM23398.1 - 0.0036 17.1 5.3 0.0062 16.4 5.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 GAM23398.1 - 0.017 15.1 6.3 0.048 13.7 6.2 1.8 1 1 0 1 1 1 0 Zinc-finger zf-RING_10 PF16685.5 GAM23398.1 - 0.034 14.3 2.6 0.054 13.6 2.6 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zinc_ribbon_5 PF13719.6 GAM23398.1 - 0.044 13.6 2.3 5.4 6.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.6 GAM23398.1 - 0.059 13.2 5.3 0.12 12.2 5.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 GAM23398.1 - 0.07 13.3 3.6 0.16 12.1 3.6 1.7 1 1 0 1 1 1 0 RING-variant domain UPF0547 PF10571.9 GAM23398.1 - 0.19 11.8 0.2 0.19 11.8 0.2 1.7 2 0 0 2 2 1 0 Uncharacterised protein family UPF0547 zf-C3HC4_4 PF15227.6 GAM23398.1 - 0.33 11.1 5.3 0.94 9.7 5.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 GAM23398.1 - 0.33 11.2 8.3 4.9 7.4 8.3 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 GAM23398.1 - 0.97 9.8 7.5 1.9 8.8 7.5 1.6 1 1 0 1 1 1 0 RING-like domain zf-P11 PF03854.14 GAM23398.1 - 1.5 8.6 7.0 7.9 6.2 7.0 2.1 1 1 1 2 2 2 0 P-11 zinc finger Hist_deacetyl PF00850.19 GAM23399.1 - 1.8e-71 241.2 1.3 3e-71 240.4 0.0 2.0 2 0 0 2 2 2 1 Histone deacetylase domain GvpG PF05120.12 GAM23399.1 - 0.44 10.6 2.4 1.3 9.1 2.4 1.7 1 0 0 1 1 1 0 Gas vesicle protein G zf-C3HC4_2 PF13923.6 GAM23399.1 - 2.2 8.2 6.1 5.4 7.0 3.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EamA PF00892.20 GAM23400.1 - 8.5e-13 48.7 34.6 2e-06 28.0 1.4 3.2 3 0 0 3 3 3 3 EamA-like transporter family zf-C2H2_assoc PF16606.5 GAM23400.1 - 1.6 9.0 4.0 1.3 9.3 1.5 2.0 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers Ank_4 PF13637.6 GAM23401.1 - 8.2e-39 131.5 21.0 3.3e-06 27.5 0.3 10.7 6 3 6 12 12 12 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM23401.1 - 5.5e-37 126.2 24.9 6.7e-07 29.8 1.4 6.5 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM23401.1 - 2.1e-34 117.1 29.8 8e-05 22.9 0.2 14.4 2 1 13 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM23401.1 - 4.4e-24 81.9 21.6 0.46 11.2 0.0 14.6 11 3 5 16 16 15 8 Ankyrin repeat DUF5049 PF16468.5 GAM23401.1 - 4.2e-12 45.8 5.6 0.12 12.2 0.0 10.2 8 3 6 14 14 14 2 Domain of unknown function (DUF5049) Ank PF00023.30 GAM23401.1 - 0.00017 21.9 17.5 27 5.4 0.0 10.4 4 2 3 7 7 7 0 Ankyrin repeat DUF1843 PF08898.10 GAM23401.1 - 0.024 15.1 1.6 9.1 6.9 0.0 4.6 6 0 0 6 6 5 0 Domain of unknown function (DUF1843) UPF0489 PF12640.7 GAM23401.1 - 0.027 14.7 0.4 0.23 11.7 0.3 2.4 1 1 0 1 1 1 0 UPF0489 domain DUF3322 PF11795.8 GAM23401.1 - 0.12 12.4 0.1 15 5.6 0.0 3.7 4 2 0 4 4 4 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) FaeA PF04703.12 GAM23401.1 - 0.13 12.6 0.6 5.8 7.4 0.0 3.7 4 0 0 4 4 4 0 FaeA-like protein DUF2790 PF10976.8 GAM23401.1 - 0.33 11.0 4.6 14 5.7 0.0 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF2790) DUF1027 PF06265.11 GAM23401.1 - 0.51 10.4 1.7 7.5 6.6 0.0 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1027) Synaptobrevin PF00957.21 GAM23402.1 - 5.5e-26 90.2 6.3 7.5e-26 89.8 6.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAM23402.1 - 4.8e-16 58.6 0.0 7.3e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain EVI2A PF05399.11 GAM23402.1 - 0.025 14.2 0.2 0.032 13.8 0.2 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Cellulase-like PF12876.7 GAM23402.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Sugar-binding cellulase-like PPO1_KFDV PF12143.8 GAM23403.1 - 0.025 14.7 0.5 0.25 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF_B2219) Sipho_Gp157 PF05565.11 GAM23403.1 - 0.17 11.9 5.9 0.33 10.9 5.9 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 CTU2 PF10288.9 GAM23403.1 - 0.48 10.7 0.1 0.48 10.7 0.1 4.1 4 1 0 4 4 4 0 Cytoplasmic tRNA 2-thiolation protein 2 Zn-C2H2_12 PF18112.1 GAM23403.1 - 1.5 9.4 4.7 2.7 8.5 1.3 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain HIGH_NTase1 PF05636.11 GAM23403.1 - 3.2 6.9 9.4 0.33 10.1 3.8 1.8 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase Peptidase_S30 PF01577.16 GAM23403.1 - 4.1 7.0 7.9 1.2 8.7 4.8 1.7 2 0 0 2 2 2 0 Potyvirus P1 protease ParA PF10609.9 GAM23404.1 - 1.5e-101 339.0 0.1 1.8e-101 338.7 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAM23404.1 - 7.4e-10 39.0 0.0 3.8e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAM23404.1 - 3.2e-07 30.5 0.2 5.7e-06 26.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 GAM23404.1 - 2.3e-06 27.0 0.9 1.4e-05 24.4 0.5 2.3 1 1 1 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 GAM23404.1 - 9.9e-05 21.9 0.1 0.17 11.3 0.0 2.5 2 1 1 3 3 3 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 GAM23404.1 - 0.00036 20.5 0.3 0.015 15.2 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MipZ PF09140.11 GAM23404.1 - 0.00077 18.8 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 GAM23404.1 - 0.0026 17.4 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAM23404.1 - 0.035 14.5 0.6 0.79 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase CBP_BcsQ PF06564.12 GAM23404.1 - 0.047 13.2 0.1 0.25 10.8 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ NACHT PF05729.12 GAM23404.1 - 0.052 13.5 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 GAM23404.1 - 0.059 12.3 0.1 0.089 11.8 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 GAM23404.1 - 0.059 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CLP1_P PF16575.5 GAM23404.1 - 0.13 12.1 0.3 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 GAM23404.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SIS_2 PF13580.6 GAM23404.1 - 0.14 12.2 0.0 1.9 8.5 0.0 2.5 1 1 1 2 2 2 0 SIS domain Zn_Tnp_IS1595 PF12760.7 GAM23404.1 - 0.72 9.9 3.0 0.75 9.8 0.0 2.4 3 0 0 3 3 2 0 Transposase zinc-ribbon domain MFS_1 PF07690.16 GAM23405.1 - 8.5e-15 54.5 35.5 8.5e-15 54.5 35.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAM23405.1 - 2.4e-06 27.1 23.9 3.2e-06 26.7 23.9 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ETRAMP PF09716.10 GAM23405.1 - 0.053 13.6 0.5 3.6 7.7 0.0 3.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Peptidase_S10 PF00450.22 GAM23406.1 - 0.079 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase DUF3224 PF11528.8 GAM23406.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) Peptidase_C48 PF02902.19 GAM23407.1 - 2.6e-41 141.8 2.0 2.6e-41 141.8 2.0 2.7 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain RNA_pol_Rpb2_6 PF00562.28 GAM23408.1 - 2.3e-109 366.1 3.6 3.7e-109 365.4 2.6 1.8 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAM23408.1 - 6.4e-30 104.2 0.0 1.1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 GAM23408.1 - 2.4e-27 94.9 0.0 4.6e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 GAM23408.1 - 4.5e-23 81.5 0.1 1.1e-22 80.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 GAM23408.1 - 4e-18 65.2 0.0 1.1e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 GAM23408.1 - 4.3e-15 55.8 0.0 7.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Pkinase PF00069.25 GAM23409.1 - 2.7e-68 230.2 0.0 5.1e-68 229.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM23409.1 - 4.1e-57 193.4 0.0 7.2e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM23409.1 - 0.00016 20.6 2.6 0.00016 20.6 2.6 4.0 3 2 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 GAM23409.1 - 0.0003 20.2 0.0 0.00053 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PBD PF00786.28 GAM23409.1 - 0.0034 17.7 0.1 0.013 15.9 0.1 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain TSC22 PF01166.18 GAM23409.1 - 0.11 12.8 0.2 0.43 10.9 0.2 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family AAA_25 PF13481.6 GAM23409.1 - 0.14 11.7 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.15 GAM23409.1 - 1.8 9.0 12.6 1.9 8.9 1.0 3.5 4 0 0 4 4 4 0 Fez1 Abhydrolase_6 PF12697.7 GAM23410.1 - 6.1e-18 66.2 0.5 8.3e-18 65.8 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM23410.1 - 3.7e-17 62.4 0.1 2.1e-16 59.9 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM23410.1 - 2.4e-14 53.6 0.3 6.3e-12 45.7 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ndr PF03096.14 GAM23410.1 - 0.00034 19.4 0.1 0.0007 18.4 0.1 1.5 2 0 0 2 2 2 1 Ndr family DLH PF01738.18 GAM23410.1 - 0.0012 18.5 0.0 0.16 11.5 0.1 3.1 2 1 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.20 GAM23410.1 - 0.0046 17.1 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.7 GAM23410.1 - 0.026 14.3 0.1 0.14 11.9 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.11 GAM23410.1 - 0.041 13.2 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.13 GAM23410.1 - 0.056 13.1 0.0 0.73 9.4 0.0 2.3 3 0 0 3 3 3 0 Serine hydrolase (FSH1) LIP PF03583.14 GAM23410.1 - 0.086 12.2 0.2 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase PGAP1 PF07819.13 GAM23410.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 GAM23410.1 - 0.091 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1100 PF06500.11 GAM23410.1 - 0.11 11.3 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_4 PF08386.10 GAM23410.1 - 0.14 12.3 0.0 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein UPF0227 PF05728.12 GAM23410.1 - 0.15 12.0 0.0 0.71 9.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) BAAT_C PF08840.11 GAM23410.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal CLTH PF10607.9 GAM23411.1 - 1.6e-32 112.4 0.3 2.6e-32 111.7 0.3 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 GAM23411.1 - 2e-22 79.5 0.2 3.1e-22 78.9 0.2 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 GAM23411.1 - 0.00016 21.5 0.0 0.00047 20.0 0.0 1.8 1 0 0 1 1 1 1 LisH Nucleolin_bd PF16725.5 GAM23411.1 - 0.0036 16.9 0.1 0.0076 15.9 0.1 1.5 1 0 0 1 1 1 1 Nucleolin binding domain DUF5582 PF17819.1 GAM23411.1 - 0.074 13.5 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5582) NT-C2 PF10358.9 GAM23412.1 - 8.1e-23 80.8 5.4 8.1e-23 80.8 5.4 2.1 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.19 GAM23412.1 - 5e-20 71.7 0.6 5e-20 71.7 0.6 3.1 3 0 0 3 3 3 1 DIL domain HMMR_N PF15905.5 GAM23412.1 - 0.00041 19.9 25.3 0.00041 19.9 25.3 6.9 2 1 5 7 7 7 1 Hyaluronan mediated motility receptor N-terminal MAD PF05557.13 GAM23412.1 - 0.0016 16.9 31.8 0.0016 16.9 31.8 5.3 1 1 3 4 4 4 2 Mitotic checkpoint protein DUF2064 PF09837.9 GAM23412.1 - 0.18 11.7 0.7 0.85 9.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) ATG16 PF08614.11 GAM23412.1 - 1.5 9.0 153.7 0.3 11.3 17.2 7.5 1 1 6 7 7 7 0 Autophagy protein 16 (ATG16) DUF3439 PF11921.8 GAM23412.1 - 1.7 8.6 11.9 6.6 6.7 11.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Golgin_A5 PF09787.9 GAM23412.1 - 3.6 7.0 143.2 0.7 9.3 30.5 6.4 2 1 5 7 7 7 0 Golgin subfamily A member 5 MBOAT PF03062.19 GAM23413.1 - 1.3e-22 80.6 30.1 2.4e-22 79.8 30.1 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 GAM23413.1 - 0.008 16.4 9.1 0.023 15.0 9.1 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Cpn60_TCP1 PF00118.24 GAM23414.1 - 2.9e-76 257.1 0.7 3.9e-76 256.7 0.7 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L27e PF01777.18 GAM23415.1 - 4.1e-28 97.6 5.8 4.1e-28 97.6 5.8 1.5 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 GAM23415.1 - 4.8e-05 23.1 0.1 0.00027 20.8 0.0 2.1 2 0 0 2 2 2 1 KOW motif Cofilin_ADF PF00241.20 GAM23416.1 - 2.4e-31 108.1 0.0 2.7e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AMP-binding PF00501.28 GAM23417.1 - 4e-74 249.7 0.0 5.3e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAM23417.1 - 8.5e-32 110.3 0.2 1.5e-31 109.5 0.2 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 GAM23417.1 - 2e-08 34.0 0.1 3.9e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM23417.1 - 1.7e-06 27.3 2.3 7e-06 25.2 1.8 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 GAM23417.1 - 1.4e-05 25.1 0.3 2.5e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAM23417.1 - 0.00036 20.0 1.9 0.00084 18.8 1.9 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM23417.1 - 0.00081 18.6 0.2 0.0017 17.5 0.2 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 GAM23417.1 - 0.0082 17.1 0.0 0.025 15.5 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 GAM23417.1 - 0.033 14.5 0.0 0.081 13.3 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site NmrA PF05368.13 GAM23417.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Bact_lectin PF18483.1 GAM23418.1 - 2.5e-19 70.1 1.9 3.3e-19 69.7 1.9 1.0 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 GAM23418.1 - 5.6e-14 52.3 0.0 8.4e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Legume lectin domain Lectin_legB PF00139.19 GAM23419.1 - 7.5e-13 48.6 0.0 9.3e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Legume lectin domain Bact_lectin PF18483.1 GAM23419.1 - 1.5e-10 41.4 0.1 1.9e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 Bacterial lectin Galanin PF01296.18 GAM23419.1 - 0.099 12.6 0.3 0.24 11.4 0.3 1.6 1 0 0 1 1 1 0 Galanin CBFB_NFYA PF02045.15 GAM23420.1 - 8.8e-26 90.3 5.8 8.8e-26 90.3 5.8 3.2 3 0 0 3 3 3 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Androgen_recep PF02166.16 GAM23420.1 - 0.00051 19.0 4.2 0.00051 19.0 4.2 2.9 2 1 0 3 3 3 1 Androgen receptor Gp_dh_C PF02800.20 GAM23421.1 - 1.6e-67 226.0 0.0 2.3e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAM23421.1 - 3.1e-37 127.0 0.2 1.4e-36 124.9 0.1 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM23421.1 - 0.015 15.4 0.0 0.049 13.8 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Trypsin_2 PF13365.6 GAM23422.1 - 0.0026 18.6 0.0 0.0045 17.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Asp PF00026.23 GAM23423.1 - 2.9e-36 125.5 0.0 7.5e-36 124.1 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM23423.1 - 8.1e-21 75.0 2.4 1.3e-20 74.4 2.4 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAM23423.1 - 3.6e-11 43.1 0.0 5.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Arm PF00514.23 GAM23424.1 - 1.6e-13 50.1 16.8 0.0001 22.2 0.5 6.2 6 1 1 7 7 7 4 Armadillo/beta-catenin-like repeat FeS_assembly_P PF01883.19 GAM23425.1 - 1.2e-09 38.2 0.0 2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein UAE_UbL PF14732.6 GAM23425.1 - 0.08 13.6 0.8 0.15 12.7 0.2 1.7 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain zf-FCS PF06467.14 GAM23425.1 - 0.28 11.1 1.6 0.4 10.7 0.5 1.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Ribosom_S12_S23 PF00164.25 GAM23426.1 - 6.2e-48 161.2 0.7 8.2e-48 160.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 RhoGEF PF00621.20 GAM23427.1 - 4.5e-50 170.4 2.8 8.9e-50 169.4 2.8 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAM23427.1 - 0.0026 18.2 0.2 0.0071 16.8 0.2 1.8 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 GAM23428.1 - 5.9e-66 222.4 0.0 9.4e-66 221.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SPRY PF00622.28 GAM23428.1 - 4.9e-63 210.6 14.4 6.2e-22 78.0 0.1 6.1 5 0 0 5 5 5 3 SPRY domain Pkinase PF00069.25 GAM23428.1 - 2.6e-47 161.4 0.0 5.4e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.17 GAM23428.1 - 2.3e-16 59.7 0.0 5e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAM23428.1 - 1.9e-15 57.0 0.0 4.3e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SUIM_assoc PF16619.5 GAM23428.1 - 0.047 13.8 0.0 0.047 13.8 0.0 14.2 11 2 2 13 13 13 0 Unstructured region C-term to UIM in Ataxin3 SAP18 PF06487.12 GAM23431.1 - 4.7e-27 94.9 0.1 7.2e-27 94.3 0.1 1.5 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Mucin PF01456.17 GAM23431.1 - 0.0084 16.1 10.2 0.014 15.4 10.2 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Clat_adaptor_s PF01217.20 GAM23431.1 - 0.062 13.2 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Gag_p17 PF00540.18 GAM23431.1 - 0.12 12.3 0.1 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 gag gene protein p17 (matrix protein) E1-E2_ATPase PF00122.20 GAM23432.1 - 2.3e-33 115.2 0.0 2.3e-33 115.2 0.0 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 GAM23432.1 - 1.2e-17 64.9 0.0 1.2e-11 45.3 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 GAM23432.1 - 2.9e-09 37.1 0.3 1.6e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 GAM23432.1 - 0.00021 21.3 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAM23432.1 - 0.028 14.1 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus RbsD_FucU PF05025.13 GAM23432.1 - 0.096 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family LIM PF00412.22 GAM23433.1 - 2.1e-62 207.2 56.1 2.2e-16 59.8 1.3 5.2 5 0 0 5 5 5 5 LIM domain FNIP PF05725.12 GAM23434.1 - 2e-26 91.9 5.7 1.7e-12 47.3 0.2 4.3 3 1 1 4 4 4 4 FNIP Repeat Glyco_hydro_18 PF00704.28 GAM23435.1 - 7.8e-23 81.7 1.8 7.8e-23 81.7 1.8 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 zf-RVT PF13966.6 GAM23436.1 - 0.02 15.6 3.5 0.036 14.8 0.3 2.7 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase Lectin_C PF00059.21 GAM23436.1 - 0.11 13.2 0.1 0.23 12.2 0.1 1.5 1 0 0 1 1 1 0 Lectin C-type domain DUF525 PF04379.14 GAM23437.1 - 8.4e-23 80.4 0.1 1.8e-22 79.4 0.1 1.6 1 0 0 1 1 1 1 ApaG domain SMI1_KNR4 PF09346.10 GAM23437.1 - 0.00079 19.8 0.3 0.0016 18.8 0.3 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) F-box PF00646.33 GAM23437.1 - 0.0035 17.2 0.2 0.0084 16.0 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM23437.1 - 0.27 11.2 3.3 1.2 9.1 0.6 2.9 3 0 0 3 3 3 0 F-box-like Podoplanin PF05808.11 GAM23438.1 - 3.1 7.9 7.2 4.5 7.4 7.2 1.3 1 0 0 1 1 1 0 Podoplanin PIG-U PF06728.13 GAM23439.1 - 1.8e-111 372.9 44.9 2.4e-111 372.5 44.9 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Orf78 PF06024.12 GAM23439.1 - 0.04 14.2 0.1 0.04 14.2 0.1 2.8 3 0 0 3 3 3 0 Orf78 (ac78) Cullin PF00888.22 GAM23440.1 - 6.3e-188 626.3 15.2 6.3e-188 626.3 15.2 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 GAM23440.1 - 1.5e-29 101.8 2.2 9.6e-29 99.2 2.5 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain GlutR_dimer PF00745.20 GAM23440.1 - 0.022 15.2 4.6 0.76 10.3 0.0 4.1 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain ALS_ss_C PF10369.9 GAM23440.1 - 0.033 14.4 0.5 0.12 12.6 0.5 2.0 1 0 0 1 1 1 0 Small subunit of acetolactate synthase WAC_Acf1_DNA_bd PF10537.9 GAM23440.1 - 0.087 13.3 1.3 15 6.2 0.2 3.4 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal Mt_ATP-synt_D PF05873.12 GAM23440.1 - 0.54 10.1 7.9 6.6 6.6 0.9 3.0 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DDE_Tnp_4 PF13359.6 GAM23441.1 - 2.3e-23 82.6 0.4 1.2e-21 77.1 0.3 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM23441.1 - 2.7e-08 33.7 1.9 4.7e-08 32.9 1.9 1.4 1 1 0 1 1 1 1 Transposase DDE domain Dicty_REP PF05086.12 GAM23442.1 - 5 5.0 6.4 7.6 4.4 6.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Rieske PF00355.26 GAM23443.1 - 5.8e-13 48.6 0.0 1.1e-12 47.8 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 GAM23443.1 - 7.1e-09 36.0 0.0 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region VCBS PF13517.6 GAM23444.1 - 0.0015 19.0 0.1 0.0051 17.4 0.1 1.9 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAM23444.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 FG-GAP repeat BBS1 PF14779.6 GAM23444.1 - 0.064 12.7 0.0 0.94 8.9 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 GAM23444.1 - 0.084 12.9 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Sld5 PF05916.11 GAM23445.1 - 4.4e-19 69.0 0.1 6.1e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein Peptidase_M28 PF04389.17 GAM23446.1 - 4.8e-36 124.3 0.1 7.6e-36 123.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 GAM23446.1 - 0.00063 19.3 0.0 0.00086 18.8 0.0 1.3 1 0 0 1 1 1 1 Nicastrin DUF3418 PF11898.8 GAM23447.1 - 0.097 11.3 0.0 0.2 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Hydantoinase_B PF02538.14 GAM23449.1 - 6.5e-216 717.7 2.4 6.7e-215 714.4 0.4 2.0 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 GAM23449.1 - 3.7e-101 338.2 0.0 6.1e-101 337.5 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAM23449.1 - 4.9e-42 143.6 0.0 5.8e-40 136.9 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region ThiS PF02597.20 GAM23449.1 - 0.03 15.0 0.0 0.11 13.2 0.0 1.9 2 0 0 2 2 2 0 ThiS family Myb_DNA-binding PF00249.31 GAM23451.1 - 6.9e-28 96.6 4.0 1.5e-11 44.3 0.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM23451.1 - 5.7e-23 80.9 1.2 1.3e-12 47.7 0.1 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GAM23451.1 - 0.0006 20.1 12.2 0.0088 16.4 0.0 3.9 3 1 1 4 4 4 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAM23451.1 - 0.049 13.8 0.9 6.5 7.0 0.1 3.2 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 RhoGEF PF00621.20 GAM23452.1 - 6.3e-40 137.3 6.7 6.3e-40 137.3 6.7 4.2 3 1 1 4 4 4 1 RhoGEF domain IQ PF00612.27 GAM23452.1 - 0.0022 17.6 1.8 0.0062 16.2 1.8 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cnd3 PF12719.7 GAM23453.1 - 3.5e-44 151.2 7.5 3.5e-44 151.2 7.5 3.4 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain DUF4811 PF16069.5 GAM23453.1 - 0.0063 16.4 1.8 0.0063 16.4 1.8 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4811) GATA PF00320.27 GAM23454.1 - 8.3e-11 41.3 1.8 1.5e-10 40.5 1.8 1.4 1 0 0 1 1 1 1 GATA zinc finger AT_hook PF02178.19 GAM23454.1 - 0.5 10.4 7.5 0.95 9.6 7.5 1.5 1 0 0 1 1 1 0 AT hook motif EB PF01683.18 GAM23456.1 - 2.3 8.6 73.3 0.1 12.9 4.6 7.8 3 1 3 6 6 6 0 EB module Prenyltrans PF00432.21 GAM23460.1 - 5.7e-43 144.3 6.9 1.2e-11 44.1 0.1 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 GAM23460.1 - 0.011 14.9 0.0 0.32 10.0 0.0 2.2 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain Histone_H2A_C PF16211.5 GAM23460.1 - 0.19 11.5 0.0 0.6 9.9 0.0 1.9 2 0 0 2 2 2 0 C-terminus of histone H2A Fcf2 PF08698.11 GAM23461.1 - 3.8e-21 75.3 2.5 3.8e-21 75.3 2.5 2.1 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing TIG PF01833.24 GAM23462.1 - 7.2e-17 61.3 48.0 1.2e-06 28.5 1.5 6.3 4 2 2 6 6 6 4 IPT/TIG domain IL6Ra-bind PF09240.10 GAM23462.1 - 0.077 13.4 0.1 31 5.1 0.0 3.5 3 0 0 3 3 3 0 Interleukin-6 receptor alpha chain, binding N2227 PF07942.12 GAM23463.1 - 1.4e-52 178.6 0.1 2e-33 115.8 0.1 2.3 1 1 1 2 2 2 2 N2227-like protein Methyltransf_23 PF13489.6 GAM23463.1 - 3e-05 23.9 0.2 0.001 18.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM23463.1 - 5.4e-05 23.9 1.9 0.00084 20.0 0.0 3.2 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM23463.1 - 0.0002 22.0 0.0 0.00078 20.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM23463.1 - 0.0012 18.6 1.1 0.003 17.4 0.0 2.0 2 2 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM23463.1 - 0.01 15.2 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1631 PF07793.11 GAM23463.1 - 0.023 13.1 0.6 0.03 12.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Methyltransf_25 PF13649.6 GAM23463.1 - 0.039 14.6 0.0 0.19 12.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain TFIIA PF03153.13 GAM23463.1 - 0.15 12.0 14.3 0.21 11.6 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 GAM23463.1 - 1.4 8.2 7.9 2 7.7 7.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Rap_GAP PF02145.15 GAM23464.1 - 7.8e-60 201.6 0.1 1.4e-59 200.8 0.0 1.4 2 0 0 2 2 2 1 Rap/ran-GAP RasGAP PF00616.19 GAM23465.1 - 1.5e-27 96.7 1.2 1.9e-14 53.9 0.0 3.2 3 0 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 GAM23465.1 - 7.3e-15 55.3 0.6 1.4e-13 51.2 0.7 2.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF4419 PF14388.6 GAM23466.1 - 1.1e-66 225.3 0.8 1.2e-66 225.2 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DnaJ_CXXCXGXG PF00684.19 GAM23467.1 - 0.00012 22.3 18.0 0.026 14.9 1.6 3.3 1 1 1 2 2 2 2 DnaJ central domain zf-rbx1 PF12678.7 GAM23467.1 - 0.19 12.0 9.0 0.31 11.3 3.1 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain Anti-TRAP PF15777.5 GAM23467.1 - 1.6 8.7 14.2 42 4.2 12.9 3.2 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 GAM23467.1 - 2.6 8.3 18.5 23 5.3 1.0 4.5 2 2 1 3 3 3 0 Family of unknown function (DUF5351) HSP70 PF00012.20 GAM23468.1 - 1.8e-248 825.6 5.6 2.1e-248 825.4 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM23468.1 - 9.2e-17 60.8 0.2 1.6e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 GAM23468.1 - 0.012 15.1 0.0 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 GAM23468.1 - 0.016 15.0 0.0 0.053 13.2 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain 6PGD PF00393.19 GAM23468.1 - 0.067 12.6 1.0 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 6-phosphogluconate dehydrogenase, C-terminal domain DUF1542 PF07564.11 GAM23468.1 - 0.73 10.0 10.3 33 4.7 5.0 3.6 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1542) ERCC4 PF02732.15 GAM23471.1 - 1.3e-16 61.2 0.6 4.3e-16 59.5 0.1 2.3 2 0 0 2 2 2 1 ERCC4 domain Glyco_hydro_59M PF17387.2 GAM23471.1 - 0.032 14.4 0.1 1.2 9.3 0.0 2.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 central domain FERM_f0 PF16511.5 GAM23471.1 - 0.099 13.0 0.1 0.27 11.6 0.1 1.8 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM AnmK PF03702.14 GAM23472.1 - 2.2e-146 487.7 0.2 2.5e-146 487.5 0.2 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase ATP_bind_1 PF03029.17 GAM23473.1 - 1.8e-78 263.7 0.0 1.8e-78 263.7 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 GAM23473.1 - 3.7e-08 33.1 0.1 6.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 GAM23473.1 - 7.9e-06 25.6 0.0 0.028 14.0 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 GAM23473.1 - 1.7e-05 24.3 0.0 0.0071 15.8 0.0 2.9 2 1 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 GAM23473.1 - 1.8e-05 24.1 1.4 0.00069 18.9 0.0 2.6 2 1 1 3 3 3 1 G-protein alpha subunit FeoB_N PF02421.18 GAM23473.1 - 2.1e-05 24.1 0.0 0.00091 18.8 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 GAM23473.1 - 0.00022 21.6 0.0 0.0004 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAM23473.1 - 0.00023 21.2 0.0 0.0021 18.1 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM23473.1 - 0.00082 19.3 1.3 1.1 9.1 0.0 3.2 4 0 0 4 4 4 2 RsgA GTPase NACHT PF05729.12 GAM23473.1 - 0.0014 18.6 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FtsK_SpoIIIE PF01580.18 GAM23473.1 - 0.0016 17.9 0.7 0.12 11.7 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 GAM23473.1 - 0.0016 18.7 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 GAM23473.1 - 0.002 17.8 0.0 0.028 14.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 GAM23473.1 - 0.0021 18.6 0.1 0.026 15.1 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 GAM23473.1 - 0.0046 16.7 0.2 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 GAM23473.1 - 0.0059 15.6 0.0 2.5 7.0 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 GAM23473.1 - 0.0061 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 GAM23473.1 - 0.0069 16.1 0.4 0.059 13.1 0.0 2.6 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 GAM23473.1 - 0.0085 15.3 0.5 0.027 13.7 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain Ras PF00071.22 GAM23473.1 - 0.0094 15.6 0.0 2.4 7.7 0.0 2.6 2 1 0 2 2 2 1 Ras family NTPase_1 PF03266.15 GAM23473.1 - 0.011 15.6 0.0 0.083 12.8 0.0 2.1 1 1 0 1 1 1 0 NTPase AAA_33 PF13671.6 GAM23473.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 GAM23473.1 - 0.014 15.6 0.0 0.24 11.6 0.0 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase KAP_NTPase PF07693.14 GAM23473.1 - 0.034 13.4 0.0 0.15 11.3 0.0 1.9 1 1 0 1 1 1 0 KAP family P-loop domain Pox_A32 PF04665.12 GAM23473.1 - 0.037 13.5 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_5 PF07728.14 GAM23473.1 - 0.038 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 GAM23473.1 - 0.042 13.3 6.9 0.36 10.3 0.0 3.2 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.18 GAM23473.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_pol_3_Rpc31 PF11705.8 GAM23473.1 - 0.051 13.8 12.4 0.096 12.9 12.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AAA_19 PF13245.6 GAM23473.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAM23473.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM23473.1 - 0.13 12.8 0.1 0.56 10.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter APS_kinase PF01583.20 GAM23473.1 - 0.14 12.1 0.0 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_25 PF13481.6 GAM23473.1 - 0.19 11.3 0.0 9.7 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAM23473.1 - 0.22 10.9 0.1 0.44 9.9 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FtsX_ECD PF18075.1 GAM23473.1 - 1.8 9.3 4.8 1.6 9.4 2.9 1.9 2 0 0 2 2 1 0 FtsX extracellular domain DTW PF03942.15 GAM23474.1 - 5.1e-24 85.1 0.0 1.8e-23 83.3 0.0 1.9 1 1 1 2 2 2 1 DTW domain zf-B_box PF00643.24 GAM23474.1 - 0.041 14.0 3.5 0.082 13.1 3.5 1.5 1 0 0 1 1 1 0 B-box zinc finger zinc_ribbon_9 PF14369.6 GAM23474.1 - 2.3 8.5 5.2 40 4.6 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon FNIP PF05725.12 GAM23475.1 - 3.5e-45 151.9 32.8 5e-09 36.2 1.0 6.0 2 1 5 8 8 8 7 FNIP Repeat LRR_8 PF13855.6 GAM23475.1 - 0.0036 17.0 4.2 0.24 11.2 2.8 3.6 2 1 1 3 3 3 2 Leucine rich repeat RHSP PF07999.11 GAM23476.1 - 0.0019 17.1 0.1 1.3 7.8 0.0 2.1 2 0 0 2 2 2 2 Retrotransposon hot spot protein NACHT PF05729.12 GAM23476.1 - 0.031 14.2 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 GAM23476.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.18 GAM23476.1 - 0.1 12.0 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 GAM23476.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 GAM23476.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_C48 PF02902.19 GAM23478.1 - 2.3e-08 34.2 0.0 2.7e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 GAM23478.1 - 0.025 14.3 0.0 0.054 13.1 0.0 1.6 1 1 0 1 1 1 0 Adenovirus endoprotease Phage_GPO PF05929.11 GAM23479.1 - 1 8.9 9.4 9 5.8 7.9 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3349 PF11829.8 GAM23479.1 - 2 9.2 5.9 0.61 10.9 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3349) DUF572 PF04502.13 GAM23479.1 - 2.5 7.6 14.7 4.5 6.8 14.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF489 PF04356.12 GAM23479.1 - 3.3 7.7 6.9 1.7 8.6 4.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF489) DUF4800 PF16057.5 GAM23479.1 - 5.9 6.1 10.5 5.2 6.3 1.7 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4800) Med22 PF06179.12 GAM23480.1 - 6.1e-21 74.6 11.1 9.1e-21 74.1 11.1 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Herpes_pp85 PF04637.12 GAM23480.1 - 0.027 12.9 4.7 0.028 12.9 4.7 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SR-25 PF10500.9 GAM23480.1 - 7.5 6.1 15.0 11 5.5 15.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC2_membrane PF01061.24 GAM23481.1 - 1.2e-75 253.6 34.9 1.3e-41 142.4 13.5 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAM23481.1 - 4.9e-44 150.2 0.4 1.1e-21 77.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 GAM23481.1 - 1.5e-08 35.2 0.0 0.0038 17.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM23481.1 - 5.8e-08 32.8 0.2 0.0001 22.2 0.1 2.6 2 1 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAM23481.1 - 1.2e-07 31.4 0.0 0.0012 18.5 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 GAM23481.1 - 2e-07 31.1 0.0 0.1 12.4 0.0 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAM23481.1 - 4.9e-07 30.1 0.0 0.035 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 GAM23481.1 - 3e-06 27.3 0.6 0.014 15.3 0.1 2.7 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_28 PF13521.6 GAM23481.1 - 4.3e-06 27.1 0.1 0.33 11.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 GAM23481.1 - 6.2e-06 26.8 0.0 0.043 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAM23481.1 - 3.9e-05 23.8 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 GAM23481.1 - 8.9e-05 22.0 0.3 3.9 6.8 0.0 3.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 GAM23481.1 - 0.00013 22.4 0.1 0.98 9.8 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 GAM23481.1 - 0.00047 19.4 39.5 0.003 16.7 16.1 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein MMR_HSR1 PF01926.23 GAM23481.1 - 0.0013 18.8 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 GAM23481.1 - 0.004 16.4 0.1 1.8 7.8 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 GAM23481.1 - 0.0043 17.4 0.0 2.8 8.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 GAM23481.1 - 0.0052 16.4 0.0 6.2 6.3 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 GAM23481.1 - 0.0054 17.3 0.0 0.063 13.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAM23481.1 - 0.0064 15.6 0.0 2 7.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein PDR_CDR PF06422.12 GAM23481.1 - 0.0068 16.3 3.7 0.06 13.3 0.1 2.9 2 0 0 2 2 2 1 CDR ABC transporter AAA_14 PF13173.6 GAM23481.1 - 0.013 15.6 0.0 8.8 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAM23481.1 - 0.018 15.0 0.0 7.6 6.4 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 GAM23481.1 - 0.02 14.8 0.2 9.1 6.2 0.3 2.4 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 GAM23481.1 - 0.027 14.7 0.3 25 5.1 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 GAM23481.1 - 0.028 14.3 0.4 13 5.7 0.0 3.5 4 0 0 4 4 3 0 NTPase AAA_5 PF07728.14 GAM23481.1 - 0.028 14.4 0.1 7.6 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 GAM23481.1 - 0.034 13.9 0.0 2.6 7.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 GAM23481.1 - 0.038 13.7 0.0 0.45 10.2 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 GAM23481.1 - 0.038 13.7 0.1 2.7 7.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain PDR_assoc PF08370.11 GAM23481.1 - 0.053 13.3 2.5 2.3 8.0 0.1 3.0 2 0 0 2 2 2 0 Plant PDR ABC transporter associated TniB PF05621.11 GAM23481.1 - 0.062 12.7 0.1 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 GAM23481.1 - 0.062 12.8 0.1 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 GAM23481.1 - 0.068 13.1 0.1 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SbcCD_C PF13558.6 GAM23481.1 - 0.12 12.7 0.0 2.9 8.2 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 GAM23481.1 - 0.12 11.9 0.6 3 7.4 0.1 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 GAM23481.1 - 0.14 11.8 0.0 7.8 6.2 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAM23481.1 - 0.2 11.0 1.1 6.1 6.2 0.1 2.7 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 GAM23481.1 - 0.2 11.6 0.1 8.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ArgJ PF01960.18 GAM23482.1 - 3e-141 470.5 13.9 3.4e-141 470.3 13.9 1.0 1 0 0 1 1 1 1 ArgJ family ATG_C PF09333.11 GAM23482.1 - 0.09 13.1 0.2 2.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Alpha_L_fucos PF01120.17 GAM23483.1 - 9.4e-53 179.9 0.1 1.2e-52 179.5 0.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 GAM23483.1 - 9.1e-16 58.2 0.0 2.7e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 Alpha-L-fucosidase C-terminal domain CENP-B_dimeris PF09026.10 GAM23484.1 - 0.017 15.5 2.4 0.64 10.4 2.7 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PhoLip_ATPase_N PF16209.5 GAM23485.1 - 5.7e-25 86.8 6.3 9.3e-25 86.1 6.3 1.3 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 GAM23485.1 - 6.3e-07 29.1 0.3 2.9e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Dynactin PF12455.8 GAM23486.1 - 2.8e-33 115.4 7.5 2.8e-33 115.4 7.5 5.3 3 2 3 6 6 6 1 Dynein associated protein CAP_GLY PF01302.25 GAM23486.1 - 2.6e-23 81.8 0.6 4.3e-23 81.1 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain VanY PF02557.17 GAM23486.1 - 0.024 14.4 0.6 0.18 11.6 0.6 2.5 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DUF2804 PF10974.8 GAM23487.1 - 5.2e-98 328.6 1.5 8e-98 328.0 1.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2804) DLIC PF05783.11 GAM23489.1 - 7.9e-104 348.1 1.1 8.9e-104 347.9 1.1 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 GAM23489.1 - 0.0052 17.0 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ribosomal_L28e PF01778.17 GAM23490.1 - 3.4e-29 101.9 0.5 4.5e-29 101.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Tma16 PF11176.8 GAM23491.1 - 4.2e-32 111.0 4.4 5.6e-32 110.6 4.4 1.2 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Pox_EPC_I2-L1 PF12575.8 GAM23492.1 - 0.031 14.5 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Rep_fac-A_3 PF08661.11 GAM23492.1 - 0.11 12.8 0.0 0.48 10.8 0.0 2.2 2 1 0 2 2 2 0 Replication factor A protein 3 HECT PF00632.25 GAM23493.1 - 1e-89 301.1 2.1 3e-89 299.5 0.1 2.5 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 GAM23493.1 - 7.5e-09 35.7 1.1 1.5e-08 34.8 1.1 1.5 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A SET PF00856.28 GAM23494.1 - 8e-15 55.6 0.2 2.5e-14 54.0 0.2 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 GAM23494.1 - 4.3e-05 23.5 12.6 4.3e-05 23.5 12.6 2.9 3 0 0 3 3 3 1 MYND finger SAF PF08666.12 GAM23494.1 - 0.24 12.1 0.0 41 4.9 0.0 2.3 2 0 0 2 2 2 0 SAF domain DUF1084 PF06454.11 GAM23495.1 - 3.3e-13 49.7 24.8 2.2e-12 46.9 24.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) AWPM-19 PF05512.11 GAM23495.1 - 0.077 13.2 1.4 0.15 12.3 0.1 2.1 2 1 1 3 3 3 0 AWPM-19-like family DUF2116 PF09889.9 GAM23495.1 - 0.11 12.4 0.0 0.11 12.4 0.0 4.0 6 0 0 6 6 6 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Str_synth PF03088.16 GAM23496.1 - 3.8e-20 71.8 0.4 6.4e-18 64.7 0.0 4.0 3 1 1 4 4 4 1 Strictosidine synthase SGL PF08450.12 GAM23496.1 - 1.3e-18 67.4 0.0 2.7e-18 66.5 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 GAM23496.1 - 3.9e-07 29.8 0.3 0.53 10.4 0.0 5.8 5 0 0 5 5 5 1 NHL repeat Arylesterase PF01731.20 GAM23496.1 - 1.6e-05 25.0 0.2 0.00022 21.3 0.0 2.9 4 0 0 4 4 4 1 Arylesterase NUDIX PF00293.28 GAM23497.1 - 1.5e-08 34.8 0.0 2.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Epimerase PF01370.21 GAM23498.1 - 7.4e-53 179.5 0.0 9.9e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM23498.1 - 2e-14 53.7 1.5 2.6e-14 53.4 0.0 1.8 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM23498.1 - 7e-05 22.1 3.1 0.00043 19.5 0.0 2.7 2 2 1 3 3 3 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAM23498.1 - 0.0003 20.0 0.1 0.00077 18.7 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAM23498.1 - 0.00087 18.5 1.4 0.0035 16.5 0.0 2.0 1 1 0 2 2 2 1 Male sterility protein SelK_SelG PF10961.8 GAM23499.1 - 2.5e-15 56.9 16.9 7.8e-15 55.3 17.0 1.6 1 1 1 2 2 2 1 Selenoprotein SelK_SelG GRP PF07172.11 GAM23499.1 - 1.1 10.0 28.0 1.6 9.5 28.0 1.2 1 0 0 1 1 1 0 Glycine rich protein family CH PF00307.31 GAM23500.1 - 9.9e-15 54.7 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain DZR PF12773.7 GAM23500.1 - 5e-05 23.2 0.4 5e-05 23.2 0.4 1.6 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.6 GAM23500.1 - 0.00041 19.6 3.9 0.0037 16.6 4.3 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 GAM23500.1 - 0.00054 19.6 6.2 0.0011 18.6 6.2 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 GAM23500.1 - 0.029 15.1 0.0 0.047 14.4 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon family zf-NADH-PPase PF09297.11 GAM23500.1 - 0.54 10.0 9.9 3 7.6 2.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain N6-adenineMlase PF10237.9 GAM23501.1 - 7.4e-45 152.6 0.4 9.1e-45 152.3 0.4 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 GAM23501.1 - 0.0043 16.7 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 XAP5 PF04921.14 GAM23502.1 - 1.8e-78 263.8 11.7 1.8e-78 263.8 11.7 2.4 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF913 PF06025.12 GAM23502.1 - 0.39 9.6 10.4 0.62 9.0 10.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ndc1_Nup PF09531.10 GAM23502.1 - 6.3 5.3 8.3 8.1 5.0 8.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_hydro_47 PF01532.20 GAM23503.1 - 1.5e-135 452.6 0.4 1.9e-135 452.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 GAM23503.1 - 0.5 9.8 4.2 56 3.1 1.4 3.8 2 1 1 3 3 3 0 Glycosyl hydrolase family 76 Phosducin PF02114.16 GAM23504.1 - 1.9e-27 95.9 4.6 5e-27 94.5 4.6 1.6 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 GAM23504.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin EF-1_beta_acid PF10587.9 GAM23504.1 - 0.023 15.1 7.9 0.023 15.1 7.9 3.4 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region DUF4407 PF14362.6 GAM23504.1 - 0.25 10.7 2.6 0.32 10.3 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM60A PF15396.6 GAM23504.1 - 2.2 8.3 6.3 3.5 7.6 6.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF1770 PF08589.10 GAM23504.1 - 3.3 8.7 7.7 0.61 11.1 2.8 2.1 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) CSRNP_N PF16019.5 GAM23504.1 - 5.7 6.8 10.2 11 5.8 10.2 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Presenilin PF01080.17 GAM23504.1 - 7.5 5.2 5.4 9.9 4.8 5.4 1.2 1 0 0 1 1 1 0 Presenilin RWD PF05773.22 GAM23505.1 - 2.6e-20 72.9 0.1 5.5e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 GAM23505.1 - 2.9e-08 34.1 0.2 2.9e-08 34.1 0.2 2.9 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Peptidase_M3 PF01432.20 GAM23506.1 - 2.7e-129 432.4 0.1 3.8e-129 431.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M32 PF02074.15 GAM23506.1 - 0.014 14.2 2.7 1.5 7.5 0.0 3.8 4 0 0 4 4 4 0 Carboxypeptidase Taq (M32) metallopeptidase HD_4 PF13328.6 GAM23507.1 - 6.6e-19 68.2 0.3 8.8e-19 67.8 0.3 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 GAM23507.1 - 0.00039 20.6 2.4 0.0007 19.8 2.4 1.4 1 0 0 1 1 1 1 HD domain DUF5399 PF17377.2 GAM23507.1 - 0.0091 15.8 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5399) B_solenoid_ydck PF18836.1 GAM23507.1 - 0.15 12.0 2.7 1.2 9.2 0.0 2.8 3 0 0 3 3 3 0 Beta solenoid repeat from YDCK Peptidase_C15 PF01470.17 GAM23508.1 - 5.9e-16 59.2 0.2 2.5e-13 50.6 0.1 2.0 1 1 1 2 2 2 2 Pyroglutamyl peptidase Ribonuc_P_40 PF08584.11 GAM23508.1 - 0.04 13.2 0.2 0.057 12.7 0.2 1.2 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit DUF4978 PF16349.5 GAM23508.1 - 0.093 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4978) VWA_2 PF13519.6 GAM23510.1 - 4.9e-07 30.4 0.0 0.0059 17.2 0.0 3.4 2 1 1 3 3 3 2 von Willebrand factor type A domain Sec23_trunk PF04811.15 GAM23510.1 - 0.00028 20.5 0.2 0.024 14.2 0.2 2.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GAM23510.1 - 0.00071 20.3 2.2 0.00073 20.2 0.1 2.2 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAM23510.1 - 0.0084 16.1 0.7 0.023 14.7 0.7 1.8 1 1 0 1 1 1 1 Sec23/Sec24 zinc finger VWA_CoxE PF05762.14 GAM23510.1 - 0.031 13.7 0.9 0.41 10.0 0.0 2.7 3 0 0 3 3 3 0 VWA domain containing CoxE-like protein Aldolase_II PF00596.21 GAM23511.1 - 1e-27 97.3 0.0 1e-13 51.6 0.0 2.1 1 1 1 2 2 2 2 Class II Aldolase and Adducin N-terminal domain NitrOD1 PF18549.1 GAM23511.1 - 0.014 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 Na_Ca_ex PF01699.24 GAM23512.1 - 1.2e-23 83.7 32.7 1.8e-14 53.9 6.8 4.0 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 GAM23512.1 - 3.1e-13 50.2 8.8 3.1e-13 50.2 8.8 5.4 5 0 0 5 5 5 1 Inner membrane component domain YjcZ_2 PF09680.10 GAM23513.1 - 5.6 6.7 6.5 1.7 8.4 2.9 2.0 2 0 0 2 2 2 0 Family of unknown function Peptidase_C54 PF03416.19 GAM23514.1 - 1.3e-91 306.8 0.3 1.3e-91 306.8 0.3 1.8 2 0 0 2 2 2 1 Peptidase family C54 Dabb PF07876.12 GAM23514.1 - 0.061 14.0 1.3 1.5 9.5 0.1 2.5 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain EFP_N PF08207.12 GAM23515.1 - 1.4e-09 37.9 0.2 3.2e-09 36.7 0.2 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Peptidase_M24 PF00557.24 GAM23516.1 - 1.8e-22 80.0 0.0 3.6e-22 79.1 0.0 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 zf-RING_2 PF13639.6 GAM23517.1 - 1.6e-12 47.6 5.7 2.6e-12 46.9 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAM23517.1 - 4.7e-11 42.2 3.9 4.7e-11 42.2 3.9 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAM23517.1 - 5.2e-08 32.6 5.3 8.6e-08 31.9 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM23517.1 - 5.3e-07 29.4 4.9 1.1e-06 28.4 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM23517.1 - 4.9e-06 26.5 3.0 1.6e-05 24.8 1.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAM23517.1 - 1.4e-05 25.2 8.7 4.7e-05 23.6 8.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAM23517.1 - 9.3e-05 22.3 3.9 0.00015 21.7 3.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAM23517.1 - 0.0022 18.0 1.1 0.005 16.9 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GAM23517.1 - 0.0029 17.4 2.8 0.0054 16.6 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAM23517.1 - 0.028 14.0 3.9 0.06 13.0 3.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 GAM23517.1 - 0.11 12.5 2.7 0.29 11.2 2.7 1.7 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 GAM23517.1 - 0.16 12.2 8.1 5.1 7.4 8.1 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 GAM23517.1 - 0.25 11.2 4.8 0.52 10.2 4.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GAM23517.1 - 0.37 11.0 2.5 0.7 10.1 2.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 ROK PF00480.20 GAM23518.1 - 9.2e-54 182.9 0.1 1.1e-53 182.6 0.1 1.1 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 GAM23518.1 - 0.036 13.1 0.2 0.057 12.4 0.2 1.3 1 0 0 1 1 1 0 Glucokinase SAM_3 PF18016.1 GAM23518.1 - 0.099 12.5 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Frag1 PF10277.9 GAM23519.1 - 4.6e-18 65.6 16.8 5.1e-18 65.4 16.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4401 PF14351.6 GAM23519.1 - 0.0013 18.1 8.0 0.0015 17.9 8.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) DUF1129 PF06570.11 GAM23519.1 - 0.0014 18.2 4.8 0.0018 17.8 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Chs7 PF12271.8 GAM23519.1 - 0.029 13.7 9.2 0.039 13.3 9.2 1.1 1 0 0 1 1 1 0 Chitin synthase export chaperone MFS_1 PF07690.16 GAM23519.1 - 0.68 8.8 15.0 0.027 13.4 2.8 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF2721 PF11026.8 GAM23519.1 - 3 7.7 8.0 5.5 6.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) FNIP PF05725.12 GAM23520.1 - 2.6e-43 145.9 42.9 3e-09 36.9 2.9 8.1 4 2 5 9 9 9 9 FNIP Repeat Ank_3 PF13606.6 GAM23521.1 - 0.0014 19.0 2.1 17 6.4 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 GAM23521.1 - 0.0026 18.3 2.9 0.3 11.7 0.1 4.1 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM23521.1 - 0.17 12.5 3.4 18 6.0 0.0 5.0 6 1 0 6 6 6 0 Ankyrin repeats (many copies) Methyltransf_11 PF08241.12 GAM23522.1 - 1.4e-19 70.5 0.0 2.4e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM23522.1 - 1.1e-16 61.3 0.0 1.8e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM23522.1 - 4.3e-11 43.4 0.0 8.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM23522.1 - 5.7e-11 42.4 0.0 1.4e-10 41.1 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM23522.1 - 3.2e-10 40.1 0.0 4.2e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM23522.1 - 1.8e-06 27.5 0.0 5.3e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family N6_N4_Mtase PF01555.18 GAM23522.1 - 0.001 18.8 0.0 0.4 10.3 0.0 2.3 2 1 0 2 2 2 2 DNA methylase Methyltransf_8 PF05148.15 GAM23522.1 - 0.0019 18.1 0.0 0.0035 17.2 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 GAM23522.1 - 0.0027 17.2 0.0 0.043 13.3 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_24 PF13578.6 GAM23522.1 - 0.018 16.1 0.0 0.034 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 GAM23522.1 - 0.022 14.9 0.0 0.047 13.8 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase NodS PF05401.11 GAM23522.1 - 0.023 14.3 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 GAM23522.1 - 0.032 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 GAM23522.1 - 0.034 13.4 0.0 0.086 12.1 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 GAM23522.1 - 0.047 13.2 0.0 0.19 11.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.12 GAM23522.1 - 0.093 12.5 0.0 1.9 8.2 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_9 PF08003.11 GAM23522.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) ThiF PF00899.21 GAM23523.1 - 1.7e-95 319.1 0.0 1.8e-65 220.7 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GAM23523.1 - 4.8e-76 256.0 4.2 7.5e-76 255.4 4.2 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 GAM23523.1 - 3.4e-26 91.2 0.1 8.2e-26 90.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 GAM23523.1 - 2.7e-14 53.6 0.0 7.6e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 GAM23523.1 - 4.6e-12 46.0 0.0 1.4e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle vWF_A PF12450.8 GAM23523.1 - 0.02 14.8 0.1 5.3 7.1 0.0 2.8 2 0 0 2 2 2 0 von Willebrand factor Shikimate_DH PF01488.20 GAM23523.1 - 0.024 14.7 0.4 0.33 11.0 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Gln-synt_C PF00120.24 GAM23524.1 - 5.8e-80 268.9 0.0 7.5e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 GAM23524.1 - 4.5e-05 23.2 0.0 9.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain TraF_2 PF13729.6 GAM23524.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Lipase_3 PF01764.25 GAM23525.1 - 2.8e-20 72.6 0.1 6.8e-20 71.4 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) DUF1350 PF07082.11 GAM23525.1 - 0.13 11.5 0.7 0.25 10.6 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1350) Mitofilin PF09731.9 GAM23525.1 - 0.19 10.5 3.4 0.3 9.9 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Dynamin_M PF01031.20 GAM23526.1 - 8.7e-104 346.7 0.8 2e-103 345.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 GAM23526.1 - 3.7e-61 206.1 0.3 5.6e-60 202.2 0.0 2.5 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 GAM23526.1 - 2.8e-32 110.7 3.1 2.8e-32 110.7 3.1 2.6 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAM23526.1 - 7.5e-05 22.8 0.1 0.00046 20.2 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM23526.1 - 0.12 12.7 0.0 2 8.7 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain FeoB_N PF02421.18 GAM23526.1 - 0.2 11.2 1.0 12 5.4 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B AIG1 PF04548.16 GAM23526.1 - 1.1 8.5 5.6 5.8 6.2 0.1 3.4 3 0 0 3 3 3 0 AIG1 family DUF5101 PF17031.5 GAM23526.1 - 1.2 9.3 4.7 1.7 8.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5101) DUF4166 PF13761.6 GAM23527.1 - 6.8e-25 87.9 0.1 1.8e-24 86.5 0.0 1.9 2 0 0 2 2 1 1 Domain of unknown function (DUF4166) DUF1731 PF08338.11 GAM23527.1 - 6.6e-12 45.1 0.0 1.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 GAM23527.1 - 4.1e-08 33.0 0.0 3.6e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family FAD_binding_2 PF00890.24 GAM23527.1 - 5.8e-06 25.7 0.3 1.8e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 GAM23527.1 - 2.7e-05 23.6 10.3 0.00062 19.1 0.3 3.9 3 1 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 GAM23527.1 - 4.4e-05 23.6 3.5 0.00028 21.0 0.6 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM23527.1 - 0.0003 20.5 1.2 0.0003 20.5 1.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Glyco_transf_4 PF13439.6 GAM23527.1 - 0.0026 17.8 0.2 0.019 15.0 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Pyr_redox_2 PF07992.14 GAM23527.1 - 0.013 14.8 1.5 0.11 11.7 1.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.6 GAM23527.1 - 0.015 15.7 0.1 0.015 15.7 0.1 3.0 3 1 0 4 4 4 0 Glycosyl transferase 4-like domain SE PF08491.10 GAM23527.1 - 0.019 14.0 0.0 0.045 12.8 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.14 GAM23527.1 - 0.059 12.2 0.6 0.12 11.2 0.6 1.5 1 0 0 1 1 1 0 Tryptophan halogenase KR PF08659.10 GAM23527.1 - 0.064 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 KR domain Lycopene_cycl PF05834.12 GAM23527.1 - 0.18 10.8 0.5 0.44 9.5 0.5 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 GAM23527.1 - 0.34 10.1 2.2 0.27 10.5 0.4 1.6 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 GAM23527.1 - 0.39 10.0 1.3 0.99 8.7 0.4 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GAM23527.1 - 1 9.9 5.0 0.48 11.0 1.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RhoGEF PF00621.20 GAM23528.1 - 2.7e-41 141.8 6.3 2.7e-41 141.8 6.3 2.1 3 0 0 3 3 3 1 RhoGEF domain IQ_SEC7_PH PF16453.5 GAM23528.1 - 2.6e-08 33.9 0.2 2.6e-08 33.9 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 GAM23528.1 - 2e-05 24.5 0.9 2e-05 24.5 0.9 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 GAM23528.1 - 2.3e-05 24.8 1.1 4.6e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 PH domain IQ PF00612.27 GAM23528.1 - 0.046 13.5 4.8 0.11 12.3 4.8 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif PsbK PF02533.15 GAM23528.1 - 0.25 11.5 1.7 0.49 10.6 1.7 1.5 1 0 0 1 1 1 0 Photosystem II 4 kDa reaction centre component FNIP PF05725.12 GAM23529.1 - 8.2e-12 45.1 10.1 0.00022 21.3 0.1 5.5 5 0 0 5 5 5 5 FNIP Repeat TPR_2 PF07719.17 GAM23532.1 - 6.6e-06 25.9 0.0 1.9e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM23532.1 - 2.2e-05 24.1 0.1 4.7e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Cgr1 PF03879.14 GAM23533.1 - 2e-11 44.2 20.4 2e-11 44.2 20.4 2.6 2 1 0 2 2 2 1 Cgr1 family Ras PF00071.22 GAM23534.1 - 1.1e-56 190.9 0.2 1.4e-56 190.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM23534.1 - 1.8e-32 112.1 0.1 7.1e-32 110.1 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM23534.1 - 3.8e-13 49.3 0.0 6e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM23534.1 - 2.5e-06 27.5 0.1 2e-05 24.7 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM23534.1 - 0.00068 19.2 0.1 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 GAM23534.1 - 0.0013 18.6 0.3 0.0046 16.8 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 GAM23534.1 - 0.0015 18.0 0.2 0.0028 17.1 0.2 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_25 PF13481.6 GAM23534.1 - 0.021 14.4 0.0 4.2 6.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain UPF0270 PF06794.12 GAM23534.1 - 0.029 14.4 0.1 0.052 13.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) AAA_14 PF13173.6 GAM23534.1 - 0.036 14.1 0.1 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAM23534.1 - 0.094 13.0 0.0 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAM23534.1 - 0.19 12.1 0.0 0.28 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 GAM23534.1 - 0.19 12.1 1.7 5 7.6 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) CH PF00307.31 GAM23535.1 - 1.1e-36 125.3 0.3 4.7e-17 62.2 0.2 2.0 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM23535.1 - 6.4e-11 41.9 0.0 0.0003 20.5 0.0 2.2 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 GAM23535.1 - 1.8e-05 24.8 0.1 0.016 15.3 0.0 2.2 2 0 0 2 2 2 2 CH-like domain in sperm protein Pur_ac_phosph_N PF16656.5 GAM23536.1 - 1.3e-17 64.1 0.1 3.9e-17 62.6 0.1 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 GAM23536.1 - 2.4e-06 28.2 0.0 4.9e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAP2_3 PF14378.6 GAM23537.1 - 2.2e-15 56.9 3.9 2.2e-15 56.9 3.9 2.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 GAM23537.1 - 6.4e-07 29.2 12.1 1.2e-06 28.3 5.0 2.6 2 0 0 2 2 2 2 PAP2 superfamily UPF0242 PF06785.11 GAM23537.1 - 0.0041 17.3 1.7 0.0077 16.4 1.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Phage_holin_3_6 PF07332.11 GAM23538.1 - 8.9 6.4 12.1 3.4 7.8 0.2 2.9 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Taxilin PF09728.9 GAM23539.1 - 9.2e-41 140.0 53.1 9.2e-41 140.0 53.1 2.2 1 1 1 2 2 2 1 Myosin-like coiled-coil protein BLOC1_2 PF10046.9 GAM23539.1 - 0.0059 16.9 3.9 0.0059 16.9 3.9 6.0 4 2 2 6 6 5 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 GAM23539.1 - 0.036 12.9 53.9 0.044 12.7 15.2 3.3 1 1 1 3 3 3 0 Spc7 kinetochore protein SlyX PF04102.12 GAM23539.1 - 0.053 14.1 1.1 0.053 14.1 1.1 5.7 4 2 0 5 5 5 0 SlyX DUF1664 PF07889.12 GAM23539.1 - 0.097 12.7 36.9 0.068 13.2 2.4 4.5 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 GAM23539.1 - 0.36 11.4 54.5 0.2 12.2 16.0 4.0 1 1 2 3 3 3 0 Apg6 coiled-coil region GAS PF13851.6 GAM23539.1 - 0.5 9.7 61.5 0.4 10.0 13.8 4.3 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding MAD PF05557.13 GAM23539.1 - 0.57 8.5 54.2 0.26 9.6 8.8 2.6 1 1 1 2 2 2 0 Mitotic checkpoint protein TPR_MLP1_2 PF07926.12 GAM23539.1 - 1.7 8.7 48.8 0.052 13.6 12.9 3.7 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DivIVA PF05103.13 GAM23539.1 - 1.8 8.7 52.4 0.19 11.8 9.1 5.3 2 1 3 6 6 6 0 DivIVA protein ERM PF00769.19 GAM23539.1 - 2.2 8.1 63.0 1.3 8.8 7.3 3.5 1 1 2 3 3 3 0 Ezrin/radixin/moesin family WEMBL PF05701.11 GAM23539.1 - 9.8 4.7 47.9 1.7 7.2 34.5 2.8 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Sec39 PF08314.11 GAM23540.1 - 1.7e-21 76.5 9.7 4.4e-11 42.0 3.2 4.3 2 1 0 2 2 2 2 Secretory pathway protein Sec39 Nbas_N PF15492.6 GAM23540.1 - 2.1e-15 56.8 0.0 1.5e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 GAM23540.1 - 0.017 15.4 0.0 0.19 12.0 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Blt1 PF12754.7 GAM23540.1 - 0.076 13.3 2.5 0.19 12.0 2.5 1.6 1 0 0 1 1 1 0 Blt1 N-terminal domain DUF2407_C PF13373.6 GAM23540.1 - 0.076 13.2 0.7 0.3 11.2 0.7 2.0 1 0 0 1 1 1 0 DUF2407 C-terminal domain Glyco_tran_28_C PF04101.16 GAM23540.1 - 0.16 12.0 1.7 0.43 10.5 1.7 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain CENP-B_dimeris PF09026.10 GAM23540.1 - 2.8 8.4 8.1 2.3 8.7 1.2 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Actin PF00022.19 GAM23541.1 - 1.3e-110 369.8 0.0 4.4e-110 368.1 0.0 1.7 1 1 0 1 1 1 1 Actin Kelch_6 PF13964.6 GAM23542.1 - 5.1e-06 26.6 1.0 0.0014 18.9 0.2 2.8 2 1 1 3 3 3 2 Kelch motif Kelch_3 PF13415.6 GAM23542.1 - 0.00011 22.3 0.2 0.63 10.4 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM23542.1 - 0.021 14.8 0.2 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.6 GAM23542.1 - 0.025 14.6 0.1 0.041 13.9 0.1 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 GAM23542.1 - 0.047 13.7 0.1 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM23542.1 - 0.12 12.0 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.6 GAM23543.1 - 1.5e-11 44.1 5.9 0.0034 17.6 0.2 5.2 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.6 GAM23543.1 - 8.5e-07 28.9 2.5 0.017 15.2 0.2 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM23543.1 - 5.4e-06 25.9 3.6 0.062 12.9 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 GAM23543.1 - 0.00014 21.8 3.0 0.015 15.2 0.2 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAM23543.1 - 0.006 16.5 0.3 0.37 10.8 0.1 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 GAM23543.1 - 0.014 15.7 0.8 18 5.8 0.0 4.5 5 1 0 5 5 5 0 Galactose oxidase, central domain DpaA_N PF16924.5 GAM23543.1 - 0.046 13.8 0.6 0.22 11.6 0.2 2.3 1 1 1 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain Baculo_p47 PF05112.12 GAM23543.1 - 0.081 12.5 6.5 0.039 13.5 4.4 1.5 2 0 0 2 2 2 0 Baculovirus P47 protein DUF5074 PF16819.5 GAM23543.1 - 0.12 12.5 0.4 6.7 6.8 0.3 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF5074) Desmo_N PF06771.11 GAM23543.1 - 0.15 12.4 1.4 0.34 11.3 1.4 1.6 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus Med30 PF11315.8 GAM23543.1 - 0.18 12.0 4.0 0.74 10.0 4.0 2.0 1 1 0 1 1 1 0 Mediator complex subunit 30 Kelch_6 PF13964.6 GAM23544.1 - 4.9e-12 45.7 4.1 0.00014 22.1 0.0 3.9 3 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 GAM23544.1 - 7.2e-08 31.9 0.3 0.0027 17.2 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 GAM23544.1 - 9.4e-08 32.0 0.8 0.045 13.8 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM23544.1 - 2.8e-07 30.7 0.2 0.34 11.3 0.0 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM23544.1 - 0.0063 16.4 1.8 0.31 11.1 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 GAM23544.1 - 0.056 13.5 4.8 0.18 11.9 0.3 3.0 3 0 0 3 3 3 0 Kelch motif SdrD_B PF17210.3 GAM23545.1 - 2.9e-73 243.3 178.8 1.3e-10 41.5 2.1 16.8 14 1 3 17 17 17 11 SdrD B-like domain Y_Y_Y PF07495.13 GAM23545.1 - 3.2e-11 43.0 7.2 0.094 12.7 0.1 9.4 11 0 0 11 11 11 3 Y_Y_Y domain DUF2012 PF09430.10 GAM23545.1 - 2.1e-08 34.3 0.0 12 6.0 0.0 8.0 8 0 0 8 8 8 2 Protein of unknown function (DUF2012) DUF2141 PF09912.9 GAM23545.1 - 4.4e-06 26.6 2.1 48 3.9 0.0 9.1 11 0 0 11 11 11 0 Uncharacterized protein conserved in bacteria (DUF2141) Nuc_N PF14448.6 GAM23545.1 - 2.1e-05 24.3 0.3 7.1 6.6 0.0 5.0 5 0 0 5 5 5 2 Nuclease N terminal DUF1439 PF07273.12 GAM23545.1 - 0.035 13.9 4.1 38 4.1 0.0 6.2 8 0 0 8 8 8 0 Protein of unknown function (DUF1439) DUF1508 PF07411.12 GAM23545.1 - 0.11 12.3 0.1 14 5.6 0.0 4.7 7 0 0 7 7 7 0 Domain of unknown function (DUF1508) GP17 PF17420.2 GAM23545.1 - 0.48 10.6 1.6 57 4.0 0.0 4.2 4 0 0 4 4 4 0 Superinfection exclusion gene product 17 Cas_NE0113 PF09623.10 GAM23546.1 - 0.098 12.3 0.2 0.32 10.7 0.1 1.8 2 0 0 2 2 2 0 CRISPR-associated protein NE0113 (Cas_NE0113) WD40 PF00400.32 GAM23547.1 - 1.2e-25 89.3 28.7 2.8e-05 24.8 0.5 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 GAM23547.1 - 2.3e-08 33.7 0.4 2.3e-08 33.7 0.4 2.6 2 1 0 3 3 3 1 WD40-like domain F-box-like PF12937.7 GAM23547.1 - 9.4e-08 31.8 0.6 5e-07 29.5 0.6 2.2 1 1 0 1 1 1 1 F-box-like Nup160 PF11715.8 GAM23547.1 - 1.4e-06 27.2 17.3 0.00078 18.2 0.7 5.6 3 2 3 6 6 6 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 GAM23547.1 - 3.1e-05 23.9 0.3 0.93 9.6 0.1 3.8 2 2 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region F-box PF00646.33 GAM23547.1 - 0.0022 17.8 9.2 0.014 15.3 0.1 3.2 3 0 0 3 3 3 2 F-box domain ANAPC4_WD40 PF12894.7 GAM23547.1 - 0.0047 17.2 0.9 11 6.4 0.0 3.5 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SSP160 PF06933.11 GAM23547.1 - 0.063 11.5 11.1 0.092 10.9 11.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PQQ_3 PF13570.6 GAM23547.1 - 0.065 13.7 0.0 42 4.8 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain F-box-like_2 PF13013.6 GAM23547.1 - 0.081 12.9 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 F-box-like domain FAM104 PF15434.6 GAM23547.1 - 9.9 6.8 7.4 7.4 7.2 4.1 2.3 2 1 0 2 2 2 0 Family 104 PH PF00169.29 GAM23548.1 - 2.4e-17 63.3 1.2 2.2e-14 53.8 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_3 PF14593.6 GAM23548.1 - 1.2e-05 25.3 0.1 2.8e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM23548.1 - 4.8e-05 23.6 0.3 0.00013 22.1 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 GAM23548.1 - 0.037 13.8 0.0 0.095 12.5 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Vac14_Fig4_bd PF11916.8 GAM23548.1 - 0.062 13.0 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding PH_9 PF15410.6 GAM23548.1 - 0.12 12.8 0.7 0.46 10.9 0.0 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 GAM23548.1 - 0.13 12.7 15.5 0.18 12.2 0.6 4.3 4 1 0 4 4 4 0 Pleckstrin homology domain DUF966 PF06136.13 GAM23548.1 - 2.5 7.8 24.5 7.2 6.2 24.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF966) Ints3 PF10189.9 GAM23549.1 - 1.5e-86 289.4 0.3 1.5e-86 289.4 0.3 2.1 2 0 0 2 2 2 1 Integrator complex subunit 3 FlhC PF05280.11 GAM23549.1 - 0.045 13.5 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Serglycin PF04360.12 GAM23549.1 - 0.15 12.0 1.8 0.24 11.3 0.4 2.1 2 0 0 2 2 2 0 Serglycin Lung_7-TM_R PF06814.13 GAM23550.1 - 6.3e-10 38.8 22.4 9.7e-10 38.2 22.4 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3246 PF11596.8 GAM23550.1 - 0.18 11.2 7.7 0.27 10.6 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CENP-B_dimeris PF09026.10 GAM23550.1 - 0.91 9.9 9.9 2.3 8.6 9.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3245 PF11595.8 GAM23550.1 - 3.3 8.2 6.5 5.2 7.5 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) TFIIF_alpha PF05793.12 GAM23550.1 - 5.4 5.5 9.6 7.8 5.0 9.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.12 GAM23550.1 - 8.7 5.6 11.8 13 5.0 11.8 1.1 1 0 0 1 1 1 0 NOA36 protein SNase PF00565.17 GAM23551.1 - 7.8e-57 190.4 1.6 4.1e-14 53.0 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 GAM23551.1 - 3.6e-13 49.6 0.0 7.7e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Tudor domain DUF2080 PF09853.9 GAM23551.1 - 0.017 14.8 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) DUF4050 PF13259.6 GAM23552.1 - 0.0018 18.7 15.6 0.0098 16.2 15.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) FAM199X PF15814.5 GAM23552.1 - 0.049 12.7 11.4 0.051 12.6 11.4 1.1 1 0 0 1 1 1 0 Protein family FAM199X Macoilin PF09726.9 GAM23552.1 - 0.076 11.6 13.0 0.081 11.5 13.0 1.0 1 0 0 1 1 1 0 Macoilin family FSA_C PF10479.9 GAM23552.1 - 0.43 8.7 9.2 0.47 8.5 9.2 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FAM76 PF16046.5 GAM23552.1 - 0.71 9.2 8.7 0.86 8.9 8.7 1.0 1 0 0 1 1 1 0 FAM76 protein Presenilin PF01080.17 GAM23552.1 - 0.73 8.5 6.9 0.8 8.4 6.9 1.0 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 GAM23552.1 - 0.96 8.2 7.7 1.1 8.0 7.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4698 PF15769.5 GAM23552.1 - 2 7.4 8.6 2.3 7.2 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) MMU163 PF17119.5 GAM23552.1 - 2.5 7.2 10.5 3.1 6.9 10.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis SSP160 PF06933.11 GAM23552.1 - 2.6 6.1 21.5 3.1 5.9 21.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 EF-hand_6 PF13405.6 GAM23553.1 - 1.4e-22 77.6 7.6 2.4e-05 23.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 GAM23553.1 - 5.6e-22 75.6 8.0 1.6e-05 24.1 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAM23553.1 - 2.5e-21 75.9 6.0 1.3e-10 41.5 0.3 2.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM23553.1 - 5.2e-19 66.8 11.3 1e-05 24.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAM23553.1 - 5.5e-18 64.6 5.3 1.4e-05 24.9 0.1 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM23553.1 - 3.4e-06 27.3 0.9 0.098 13.0 0.2 2.8 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 GAM23553.1 - 0.00012 21.8 3.7 2.2 8.2 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 GAM23553.1 - 0.00016 21.9 0.1 0.65 10.4 0.0 3.0 1 1 2 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 GAM23553.1 - 0.0017 18.2 1.8 0.085 12.8 0.1 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 GAM23553.1 - 0.0048 17.7 0.2 9.3 7.2 0.0 2.9 1 1 2 3 3 3 2 EF-hand domain TerB PF05099.13 GAM23553.1 - 0.019 14.9 0.1 0.26 11.3 0.0 2.3 1 1 2 3 3 3 0 Tellurite resistance protein TerB NADPH_Ox PF08414.10 GAM23553.1 - 0.026 14.9 0.2 1.1 9.6 0.0 2.3 1 1 0 2 2 2 0 Respiratory burst NADPH oxidase EF-hand_2 PF09068.11 GAM23553.1 - 0.053 13.7 0.0 17 5.6 0.0 2.7 2 2 1 3 3 3 0 EF hand Caleosin PF05042.13 GAM23553.1 - 0.11 12.4 0.7 55 3.6 0.0 3.2 2 2 1 3 3 3 0 Caleosin related protein EF-hand_3 PF09069.11 GAM23553.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand Poxvirus PF06227.12 GAM23553.1 - 0.16 11.8 0.1 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 dsDNA Poxvirus PROCN PF08083.11 GAM23554.1 - 4.7e-224 743.6 11.1 4.1e-151 503.3 3.8 2.3 2 0 0 2 2 2 2 PROCN (NUC071) domain PRP8_domainIV PF12134.8 GAM23554.1 - 7.6e-124 411.8 0.6 1.4e-123 411.0 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core PRO8NT PF08082.11 GAM23554.1 - 2.8e-82 274.1 3.9 7.1e-82 272.8 3.9 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U6-snRNA_bdg PF10596.9 GAM23554.1 - 1.6e-81 271.9 3.6 8.5e-57 191.5 0.3 2.7 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 GAM23554.1 - 4.8e-71 237.1 0.1 9.6e-71 236.1 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 GAM23554.1 - 4.3e-46 155.8 0.9 1.1e-45 154.5 0.6 1.9 2 0 0 2 2 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 GAM23554.1 - 1.5e-45 153.4 0.9 4.7e-45 151.9 0.9 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.16 GAM23554.1 - 1.3e-17 64.5 1.6 3e-16 60.1 2.5 2.7 2 1 0 2 2 2 1 Hom_end-associated Hint Intein_splicing PF14890.6 GAM23554.1 - 5.1e-16 58.8 0.2 5.5e-09 36.1 0.0 4.0 3 1 0 3 3 3 2 Intein splicing domain JAB PF01398.21 GAM23554.1 - 5e-09 36.2 0.0 1.5e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4423 PF14394.6 GAM23554.1 - 5.5e-06 26.2 0.1 1.3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) Vint PF14623.6 GAM23554.1 - 0.0011 18.8 0.4 2.8 7.7 0.0 3.4 3 0 0 3 3 3 1 Hint-domain Hint PF01079.20 GAM23554.1 - 0.0016 18.0 0.1 0.73 9.3 0.0 2.7 2 0 0 2 2 2 2 Hint module Phage_TAC_8 PF10666.9 GAM23554.1 - 0.0036 17.6 0.3 1.3 9.2 0.2 3.3 3 0 0 3 3 3 1 Phage tail assembly chaperone protein Gp14 ()A118 CtsR_C PF17727.1 GAM23554.1 - 0.063 13.4 0.1 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain WD40 PF00400.32 GAM23555.1 - 7e-16 58.3 18.2 8.4e-05 23.3 0.1 5.9 6 1 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 GAM23555.1 - 2.8e-07 29.6 7.4 0.051 12.2 0.1 4.4 2 2 3 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAM23555.1 - 3.9e-05 23.9 2.9 0.67 10.3 0.1 4.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GAM23555.1 - 0.033 13.8 0.4 0.06 12.9 0.4 1.3 1 0 0 1 1 1 0 PQQ-like domain LRAT PF04970.13 GAM23555.1 - 0.033 14.5 1.7 0.11 12.8 0.4 2.0 2 0 0 2 2 2 0 Lecithin retinol acyltransferase eIF3g PF12353.8 GAM23556.1 - 7e-23 81.4 2.3 1.2e-22 80.6 2.3 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 GAM23556.1 - 2e-19 69.2 0.0 3.8e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM23556.1 - 0.0015 18.1 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM23556.1 - 0.037 14.0 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CDC27 PF09507.10 GAM23558.1 - 0.023 14.1 11.9 0.026 13.9 11.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.12 GAM23558.1 - 0.13 11.9 16.1 0.17 11.6 16.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 GAM23558.1 - 2.3 7.9 10.3 4.1 7.1 10.3 1.5 1 1 0 1 1 1 0 FAM176 family V_ATPase_I PF01496.19 GAM23558.1 - 3 5.7 4.0 4.5 5.1 4.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_pol_phi PF04931.13 GAM23558.1 - 6.3 4.8 12.3 9.4 4.2 12.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Rhodanese PF00581.20 GAM23559.1 - 2.1e-26 92.5 0.0 3.7e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Lin-8 PF03353.15 GAM23560.1 - 0.096 12.2 17.5 0.65 9.5 1.0 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist NLPC_P60 PF00877.19 GAM23560.1 - 5.3 7.1 12.3 23 5.1 12.3 2.1 1 1 0 1 1 1 0 NlpC/P60 family DUF5126 PF17166.4 GAM23561.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) PA26 PF04636.13 GAM23562.1 - 0.016 14.1 0.1 0.016 14.1 0.1 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Stealth_CR4 PF17103.5 GAM23563.1 - 3.4e-23 81.3 0.1 6.4e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 GAM23563.1 - 3.5e-05 23.6 1.0 7.2e-05 22.6 1.0 1.6 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 EF-hand_1 PF00036.32 GAM23563.1 - 0.0032 16.9 0.2 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 GAM23563.1 - 0.01 15.3 0.1 0.028 13.9 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 GAM23563.1 - 0.032 14.7 0.0 0.085 13.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 GAM23563.1 - 0.11 12.4 0.3 0.66 10.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Bcr-Abl_Oligo PF09036.10 GAM23563.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain IMUP PF15761.5 GAM23563.1 - 1.7 9.4 9.7 3.7 8.3 9.7 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF3439 PF11921.8 GAM23563.1 - 1.8 8.6 8.9 4.1 7.4 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SR-25 PF10500.9 GAM23563.1 - 3.1 7.3 8.4 7.2 6.2 8.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Stealth_CR2 PF11380.8 GAM23564.1 - 6e-46 155.1 0.0 1.4e-45 153.9 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Notch PF00066.17 GAM23564.1 - 9.3e-13 48.4 34.5 1.6e-06 28.5 12.5 2.5 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 GAM23564.1 - 2.9e-10 39.7 0.4 6.6e-10 38.6 0.4 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 GAM23564.1 - 0.004 17.0 0.4 0.01 15.7 0.4 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Ole-e-6 PF09253.10 GAM23564.1 - 3.3 7.7 17.0 5.9 6.9 3.0 2.5 2 0 0 2 2 2 0 Pollen allergen ole e 6 Pyr_redox_2 PF07992.14 GAM23565.1 - 1e-40 139.9 0.1 1.6e-40 139.2 0.1 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM23565.1 - 1.3e-16 60.9 3.8 4.2e-12 46.5 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM23565.1 - 9e-09 35.0 0.1 0.0003 20.1 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM23565.1 - 3.4e-07 30.4 0.0 4.3e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAM23565.1 - 1.2e-05 24.4 0.2 0.00089 18.2 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.24 GAM23565.1 - 1.8e-05 24.5 1.6 0.001 18.7 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 GAM23565.1 - 2e-05 25.0 0.5 0.24 11.9 0.0 2.6 2 1 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.6 GAM23565.1 - 6.6e-05 22.2 0.0 0.016 14.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 GAM23565.1 - 0.00029 20.1 1.0 0.00062 19.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 GAM23565.1 - 0.00031 19.9 0.3 0.48 9.5 0.1 3.5 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAM23565.1 - 0.00041 19.7 0.2 0.041 13.1 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 GAM23565.1 - 0.0006 19.1 1.1 0.031 13.5 0.0 2.5 2 1 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 GAM23565.1 - 0.0014 17.5 3.5 0.018 13.8 0.1 2.9 4 0 0 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.21 GAM23565.1 - 0.002 17.4 0.3 0.68 9.2 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 GAM23565.1 - 0.0038 16.3 0.7 0.89 8.5 0.2 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 GAM23565.1 - 0.006 16.2 0.4 0.77 9.3 0.1 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 GAM23565.1 - 0.011 15.8 1.9 3.5 7.6 0.1 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 GAM23565.1 - 0.015 15.5 1.4 1.2 9.4 0.3 2.5 2 0 0 2 2 2 0 TrkA-N domain FAD_oxidored PF12831.7 GAM23565.1 - 0.018 14.4 1.0 0.07 12.5 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Phage_30_8 PF06019.11 GAM23565.1 - 0.063 13.2 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Phage GP30.8 protein Amino_oxidase PF01593.24 GAM23565.1 - 0.081 12.2 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAM23566.1 - 9.6e-48 162.9 1.9 1.2e-47 162.5 1.9 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM23566.1 - 6.4e-18 65.1 0.6 2.5e-14 53.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM23566.1 - 2.7e-10 40.0 0.5 1.9e-07 30.7 0.3 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM23566.1 - 4.7e-09 36.0 0.1 0.001 18.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAM23566.1 - 3.6e-07 30.1 1.7 0.0018 17.9 0.0 3.9 3 1 2 5 5 5 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM23566.1 - 6.7e-07 29.4 0.1 0.0031 17.7 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAM23566.1 - 9.6e-07 28.3 0.1 0.00017 20.8 0.0 2.4 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 GAM23566.1 - 2.5e-06 26.8 0.2 0.058 12.4 0.0 3.0 2 1 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 GAM23566.1 - 7.5e-06 24.9 0.7 0.27 9.9 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein Trp_halogenase PF04820.14 GAM23566.1 - 4.4e-05 22.5 0.3 0.09 11.6 0.0 2.6 2 0 0 2 2 2 2 Tryptophan halogenase TrkA_N PF02254.18 GAM23566.1 - 9.2e-05 22.7 1.4 1.2 9.4 0.1 3.3 3 0 0 3 3 3 2 TrkA-N domain NAD_binding_7 PF13241.6 GAM23566.1 - 9.5e-05 22.8 0.6 0.21 12.0 0.1 2.7 2 1 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_9 PF13454.6 GAM23566.1 - 0.00025 21.1 1.4 1.9 8.4 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 GAM23566.1 - 0.00098 19.4 0.3 0.99 9.7 0.1 2.5 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 GAM23566.1 - 0.0032 16.6 1.0 0.16 11.0 0.1 2.9 3 0 0 3 3 3 1 FAD binding domain DUF1188 PF06690.11 GAM23566.1 - 0.0036 16.9 0.1 0.048 13.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) Thi4 PF01946.17 GAM23566.1 - 0.0038 16.5 0.1 0.66 9.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Zeta_toxin PF06414.12 GAM23566.1 - 0.0051 16.1 0.0 0.02 14.2 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin DUF2368 PF10166.9 GAM23566.1 - 0.15 11.6 0.1 0.69 9.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) FAD_oxidored PF12831.7 GAM23566.1 - 0.18 11.1 0.9 5.3 6.3 0.1 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase DUF812 PF05667.11 GAM23567.1 - 1.3e-175 585.8 26.8 1.3e-175 585.8 26.8 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF812) ANAPC4 PF12896.7 GAM23567.1 - 0.011 15.2 0.9 0.011 15.2 0.9 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 TSC22 PF01166.18 GAM23567.1 - 0.98 9.8 5.9 6.1 7.2 2.2 3.9 3 0 0 3 3 3 0 TSC-22/dip/bun family ALIX_LYPXL_bnd PF13949.6 GAM23567.1 - 2.3 7.4 37.4 0.61 9.3 0.7 3.5 1 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV Mvb12 PF09452.10 GAM23567.1 - 3.3 8.2 8.5 1.5 9.3 2.2 3.2 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 GAS PF13851.6 GAM23567.1 - 3.5 6.9 44.2 1.1 8.6 13.7 3.3 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 GAM23567.1 - 5.3 6.6 41.2 0.086 12.5 30.1 3.0 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF5600 PF18150.1 GAM23567.1 - 9.1 6.9 10.9 0.42 11.2 0.4 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF5600) Phage_holin_3_1 PF05106.12 GAM23568.1 - 0.048 14.1 1.6 0.86 10.1 0.1 2.5 2 1 0 2 2 2 0 Phage holin family (Lysis protein S) DUF3391 PF11871.8 GAM23568.1 - 0.21 12.1 0.0 0.3 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) TMEM135_C_rich PF15982.5 GAM23569.1 - 8e-25 88.0 0.3 1.3e-24 87.4 0.3 1.2 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 FMN_dh PF01070.18 GAM23570.1 - 9.4e-133 442.5 0.0 1.1e-132 442.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 GAM23570.1 - 6.1e-08 32.0 0.8 3.6e-07 29.5 0.3 2.3 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 GAM23570.1 - 1.4e-07 31.1 1.8 0.00055 19.3 0.2 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 GAM23570.1 - 5e-07 29.4 1.5 7.8e-07 28.8 1.5 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 GAM23570.1 - 3.7e-05 23.0 0.1 7.2e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 GAM23570.1 - 0.00017 21.1 0.7 0.0063 16.0 0.1 2.5 2 1 1 3 3 3 1 Histidine biosynthesis protein Dus PF01207.17 GAM23570.1 - 0.0003 20.0 0.8 0.0034 16.5 0.6 2.4 2 1 1 3 3 3 1 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 GAM23570.1 - 0.0015 18.0 0.1 0.048 13.1 0.0 2.4 1 1 1 2 2 2 1 Glycerol-3-phosphate responsive antiterminator DHO_dh PF01180.21 GAM23570.1 - 0.0018 17.5 0.1 0.015 14.5 0.0 2.3 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase DHDPS PF00701.22 GAM23570.1 - 0.021 13.6 0.0 0.11 11.2 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family TMP-TENI PF02581.17 GAM23570.1 - 0.15 11.4 0.1 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase tRNA-synt_2 PF00152.20 GAM23571.1 - 2.6e-77 260.0 0.0 3.8e-77 259.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAM23571.1 - 7.9e-09 35.4 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAM23571.1 - 5.9e-06 26.0 0.0 0.0087 15.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) GST_C_3 PF14497.6 GAM23572.1 - 3e-20 72.3 0.0 6.7e-20 71.1 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM23572.1 - 2.3e-07 30.9 0.0 8.6e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM23572.1 - 3.1e-07 30.6 0.0 5.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM23572.1 - 2.6e-06 27.3 0.0 7.8e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain FliP PF00813.20 GAM23573.1 - 0.0024 17.8 5.2 0.0037 17.2 5.2 1.2 1 0 0 1 1 1 1 FliP family CTNNB1_binding PF08347.11 GAM23573.1 - 0.0027 17.9 2.4 0.0036 17.5 2.4 1.2 1 0 0 1 1 1 1 N-terminal CTNNB1 binding DDHD PF02862.17 GAM23573.1 - 0.0032 17.7 4.0 0.004 17.4 4.0 1.2 1 0 0 1 1 1 1 DDHD domain HSP20 PF00011.21 GAM23573.1 - 0.0065 16.6 0.6 0.035 14.3 0.0 2.4 2 1 0 2 2 2 1 Hsp20/alpha crystallin family AAA_23 PF13476.6 GAM23573.1 - 0.021 15.3 10.5 0.031 14.8 10.5 1.3 1 0 0 1 1 1 0 AAA domain EPL1 PF10513.9 GAM23573.1 - 0.022 15.1 8.1 0.03 14.7 8.1 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Suf PF05843.14 GAM23573.1 - 0.024 14.6 9.6 0.029 14.3 9.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SMYLE_N PF18615.1 GAM23573.1 - 0.037 13.6 7.9 0.047 13.3 7.9 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF572 PF04502.13 GAM23573.1 - 0.049 13.3 8.5 0.065 12.9 8.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CSG2 PF16965.5 GAM23573.1 - 0.053 12.5 2.3 0.07 12.1 2.3 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator CLN3 PF02487.17 GAM23573.1 - 0.12 11.5 7.5 0.16 11.0 7.5 1.2 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 GAM23573.1 - 0.19 11.7 5.9 0.24 11.4 5.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MMR1 PF08505.10 GAM23573.1 - 0.47 10.7 15.4 0.63 10.3 15.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Kei1 PF08552.11 GAM23573.1 - 0.52 10.2 6.0 0.76 9.6 6.0 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RR_TM4-6 PF06459.12 GAM23573.1 - 0.55 10.0 10.6 0.75 9.6 10.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ORC_WH_C PF18137.1 GAM23573.1 - 0.57 10.2 10.4 1 9.5 10.4 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal LMBR1 PF04791.16 GAM23573.1 - 0.72 8.7 5.5 0.85 8.5 5.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.9 GAM23573.1 - 0.74 8.0 24.1 0.92 7.7 24.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TERB2 PF15101.6 GAM23573.1 - 0.95 9.5 15.1 2 8.5 15.1 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PepSY_TM PF03929.16 GAM23573.1 - 1 8.9 4.5 1.3 8.6 4.5 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Sec62 PF03839.16 GAM23573.1 - 1.1 8.8 9.2 1.5 8.3 9.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 GAM23573.1 - 1.1 8.0 13.8 1.4 7.6 13.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4638 PF15472.6 GAM23573.1 - 1.4 8.6 10.0 2 8.1 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Membralin PF09746.9 GAM23573.1 - 1.8 7.5 7.2 2.4 7.1 7.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein UPF0560 PF10577.9 GAM23573.1 - 1.9 6.9 17.2 2.4 6.5 17.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ECH_2 PF16113.5 GAM23573.1 - 1.9 7.9 8.0 2.8 7.4 8.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Exonuc_VII_L PF02601.15 GAM23573.1 - 2.1 7.8 17.6 3 7.3 17.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM60A PF15396.6 GAM23573.1 - 4 7.4 10.0 5.6 6.9 10.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Gti1_Pac2 PF09729.9 GAM23573.1 - 4.2 7.4 12.6 6.6 6.8 12.6 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family ALMT PF11744.8 GAM23573.1 - 4.4 6.0 12.2 5.8 5.6 12.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 GAM23573.1 - 4.6 7.1 40.4 6.4 6.7 40.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APC_u15 PF16636.5 GAM23573.1 - 7.4 7.1 21.6 17 5.9 21.6 1.6 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 CPSF100_C PF13299.6 GAM23573.1 - 8.5 6.5 12.5 15 5.7 12.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF5352 PF17303.2 GAM23574.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.8 3 1 0 3 3 3 0 Family of unknown function (DUF5352) Pkinase PF00069.25 GAM23575.1 - 7.2e-50 169.8 0.5 4.9e-43 147.4 0.3 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM23575.1 - 8e-37 126.9 0.9 3.2e-33 115.1 0.6 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM23575.1 - 6.6e-06 25.2 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM23575.1 - 0.0024 16.9 0.2 0.0036 16.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM23575.1 - 0.029 14.3 0.0 9.1 6.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 GAM23575.1 - 0.055 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM23575.1 - 0.085 12.2 0.1 0.28 10.5 0.1 1.8 2 0 0 2 2 2 0 Kinase-like Myosin_head PF00063.21 GAM23577.1 - 3.4e-219 729.5 0.2 9.7e-179 595.8 0.1 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_16 PF13191.6 GAM23577.1 - 0.001 19.5 0.0 0.0032 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM23577.1 - 0.025 14.9 0.0 0.063 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 GAM23577.1 - 0.056 12.4 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.26 GAM23577.1 - 0.086 12.5 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 GAM23577.1 - 0.12 12.9 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 GAM23577.1 - 0.16 11.1 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 GAM23577.1 - 0.21 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Pkinase_Tyr PF07714.17 GAM23578.1 - 9.1e-52 175.9 0.0 1.6e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM23578.1 - 6.1e-44 150.4 0.0 1e-43 149.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 GAM23578.1 - 2e-34 119.1 0.0 3.6e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 GAM23578.1 - 4.5e-25 88.2 0.1 1e-24 87.0 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM23578.1 - 5.7e-13 48.8 0.1 1.1e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 GAM23578.1 - 1.7e-06 27.6 0.1 3.4e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_8 PF13855.6 GAM23578.1 - 1.2e-05 25.0 1.2 3.5e-05 23.5 1.2 1.9 1 0 0 1 1 1 1 Leucine rich repeat Gtr1_RagA PF04670.12 GAM23578.1 - 0.00025 20.5 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region LRR_4 PF12799.7 GAM23578.1 - 0.00053 20.3 2.8 0.043 14.3 2.2 3.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) MMR_HSR1 PF01926.23 GAM23578.1 - 0.0009 19.3 0.0 0.0028 17.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 GAM23578.1 - 0.002 17.9 0.2 0.0045 16.8 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 GAM23578.1 - 0.0076 16.8 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 GAM23578.1 - 0.022 14.6 0.1 0.083 12.8 0.1 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 GAM23578.1 - 0.038 14.3 0.1 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 GAM23578.1 - 0.051 13.3 0.1 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 GAM23578.1 - 0.12 11.9 0.1 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 GAM23578.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 GAM23578.1 - 0.15 11.3 0.4 0.29 10.4 0.4 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 GAM23578.1 - 0.19 12.1 0.0 0.45 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 GAM23578.1 - 0.23 10.5 0.4 0.65 9.1 0.1 1.8 2 0 0 2 2 2 0 MCM P-loop domain SPX PF03105.19 GAM23578.1 - 4.7 7.0 12.0 8.2 6.2 12.0 1.3 1 0 0 1 1 1 0 SPX domain Peptidase_C39_2 PF13529.6 GAM23579.1 - 6.4e-10 39.8 0.0 2.6e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase_C39 like family Guanylate_cyc_2 PF09778.9 GAM23579.1 - 0.00099 18.5 0.2 0.0044 16.4 0.2 2.0 1 1 0 1 1 1 1 Guanylylate cyclase Peptidase_C70 PF12385.8 GAM23579.1 - 0.035 14.1 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 GAM23579.1 - 0.077 12.8 0.1 0.14 11.9 0.0 1.4 2 0 0 2 2 2 0 Peptidase C39 family Gar1 PF04410.14 GAM23580.1 - 1.5e-14 54.0 0.0 2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region SH3BGR PF04908.15 GAM23581.1 - 2.3e-15 56.5 0.1 3.4e-15 56.0 0.1 1.3 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 GAM23581.1 - 2.1e-10 40.7 0.0 2.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 GAM23581.1 - 0.11 12.9 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RhoGAP PF00620.27 GAM23582.1 - 5.1e-36 123.8 0.3 1.4e-35 122.3 0.3 1.7 1 0 0 1 1 1 1 RhoGAP domain BAR_3 PF16746.5 GAM23582.1 - 2.1e-15 57.1 8.4 2.1e-15 57.1 8.4 2.3 3 0 0 3 3 3 1 BAR domain of APPL family BAR PF03114.18 GAM23582.1 - 7.3e-09 35.6 7.8 2e-08 34.2 7.8 1.7 1 1 0 1 1 1 1 BAR domain BAR_2 PF10455.9 GAM23582.1 - 5.9e-05 22.3 9.7 7.2e-05 22.1 8.9 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Nod1 PF17114.5 GAM23582.1 - 0.011 15.8 0.2 0.026 14.7 0.2 1.6 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 DUF4208 PF13907.6 GAM23582.1 - 1.4 9.4 5.6 0.41 11.1 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) TPR_MLP1_2 PF07926.12 GAM23582.1 - 1.5 8.9 7.9 0.17 12.0 0.9 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DSPc PF00782.20 GAM23583.1 - 2.7e-10 40.2 11.4 3.2e-06 27.0 0.0 3.4 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain tRNA-synt_1 PF00133.22 GAM23584.1 - 5.9e-13 47.9 0.0 6.9e-13 47.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GAM23584.1 - 4.8e-10 38.7 0.0 6e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAM23585.1 - 1.1e-36 126.3 0.0 2.5e-36 125.2 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM23585.1 - 4.7e-13 49.4 0.6 2.9e-12 46.8 0.6 2.3 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM23585.1 - 1.7e-08 33.6 0.2 2.9e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAM23585.1 - 7.2e-06 25.6 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain PhyH PF05721.13 GAM23586.1 - 3.2e-07 30.8 0.0 8.1e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 GAM23586.1 - 0.00082 18.2 0.4 2.9 6.6 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 GAM23586.1 - 0.0018 19.1 0.0 0.0036 18.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 GAM23586.1 - 0.029 14.8 0.0 0.13 12.7 0.0 1.9 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase NIF PF03031.18 GAM23587.1 - 2.2e-24 86.0 1.2 4.3e-24 85.1 1.2 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 GAM23587.1 - 1.8e-07 30.8 0.0 4.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 GAM23587.1 - 0.046 13.8 0.2 0.15 12.1 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain Mucin PF01456.17 GAM23587.1 - 0.29 11.1 17.4 0.43 10.6 17.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Arf PF00025.21 GAM23588.1 - 2.1e-77 258.5 0.1 2.5e-77 258.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM23588.1 - 1.5e-14 54.2 0.0 2.2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM23588.1 - 1.7e-14 53.7 0.0 2e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAM23588.1 - 1.4e-13 50.8 1.9 9.3e-10 38.2 0.5 2.6 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.22 GAM23588.1 - 2.7e-12 46.6 0.0 3e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAM23588.1 - 1.4e-11 44.2 0.0 1.7e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM23588.1 - 2.4e-05 24.4 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAM23588.1 - 0.0051 16.1 0.8 0.025 13.9 0.4 1.9 1 1 1 2 2 2 1 6-phosphofructo-2-kinase Pkinase_Tyr PF07714.17 GAM23589.1 - 4.6e-59 199.8 0.0 6.7e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM23589.1 - 1.7e-51 175.1 0.0 2.7e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAM23589.1 - 3.6e-07 29.3 0.0 6.1e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Cbl_N2 PF02761.14 GAM23589.1 - 6.4e-06 26.8 0.1 2.4e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain SH2 PF00017.24 GAM23589.1 - 0.0004 20.4 0.0 0.00088 19.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 GAM23589.1 - 0.055 13.4 0.2 0.61 10.0 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3439 PF11921.8 GAM23589.1 - 0.064 13.2 2.1 0.14 12.1 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 GAM23589.1 - 0.14 10.3 6.3 0.2 9.8 6.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_UL25 PF01499.16 GAM23589.1 - 0.17 10.3 0.7 0.27 9.7 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Hydrolase_4 PF12146.8 GAM23591.1 - 2.2e-09 36.9 0.4 4.2e-06 26.2 0.3 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM23591.1 - 9.6e-08 31.8 0.0 0.0041 16.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1749 PF08538.10 GAM23591.1 - 0.00023 20.3 0.0 0.00031 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.16 GAM23591.1 - 0.00025 20.9 0.7 0.032 14.1 0.0 2.8 1 1 2 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 GAM23591.1 - 0.00043 20.0 0.0 0.8 9.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 GAM23591.1 - 0.0016 18.0 0.1 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 GAM23591.1 - 0.006 17.2 0.0 0.013 16.1 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 GAM23591.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PAE PF03283.13 GAM23591.1 - 0.024 13.8 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase DUF2974 PF11187.8 GAM23591.1 - 0.047 13.3 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pterin_4a PF01329.19 GAM23592.1 - 7.7e-23 80.5 0.1 1.5e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Cullin PF00888.22 GAM23593.1 - 1.8e-139 466.2 22.3 2.4e-139 465.8 22.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAM23593.1 - 2.5e-24 85.1 1.0 6.3e-24 83.8 1.0 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain RGS PF00615.19 GAM23593.1 - 0.0061 16.8 7.4 0.67 10.2 3.1 3.6 2 1 0 2 2 2 2 Regulator of G protein signaling domain TIG PF01833.24 GAM23594.1 - 4e-15 55.6 24.6 1e-06 28.7 1.3 4.8 4 0 0 4 4 4 3 IPT/TIG domain SKG6 PF08693.10 GAM23594.1 - 0.029 13.8 1.5 0.065 12.7 1.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_8 PF13855.6 GAM23594.1 - 0.068 12.9 9.7 0.021 14.6 2.9 3.5 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 GAM23594.1 - 5.7 7.5 22.6 3.1 8.3 4.2 5.3 3 1 2 6 6 6 0 Leucine Rich repeats (2 copies) Peptidase_M16_C PF05193.21 GAM23595.1 - 1.3e-11 44.8 0.1 8.5e-10 38.9 0.0 2.4 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAM23595.1 - 1.1e-08 35.2 0.0 6.5e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) FANCI_S2 PF14676.6 GAM23595.1 - 0.065 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 FANCI solenoid 2 Fe-S_biosyn PF01521.20 GAM23596.1 - 2.2e-15 56.8 0.3 2.5e-15 56.6 0.3 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Receptor_IA-2 PF11548.8 GAM23596.1 - 0.11 12.4 0.1 6.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 Adhesin_Dr PF04619.12 GAM23596.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Dr-family adhesin ParB PF08775.10 GAM23597.1 - 0.031 14.7 0.2 1.2 9.6 0.1 2.3 1 1 1 2 2 2 0 ParB family LRR_9 PF14580.6 GAM23598.1 - 1.4e-19 70.3 32.3 4.4e-13 49.1 3.3 4.2 2 1 2 4 4 4 3 Leucine-rich repeat LRR_4 PF12799.7 GAM23598.1 - 3.7e-19 68.5 33.9 0.00023 21.5 4.7 5.7 4 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM23598.1 - 6.4e-19 67.5 38.1 7.2e-08 32.1 3.7 5.0 2 1 1 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 GAM23598.1 - 0.074 13.1 37.7 3.5 7.9 0.2 9.0 8 1 1 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.33 GAM23598.1 - 0.09 13.4 17.8 69 4.6 1.7 8.1 8 1 0 8 8 8 0 Leucine Rich Repeat Abhydrolase_1 PF00561.20 GAM23599.1 - 6.6e-31 107.9 0.0 8.9e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM23599.1 - 6.3e-09 35.5 0.0 2e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM23599.1 - 3.2e-08 34.5 0.0 4.7e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 GAM23599.1 - 0.00038 20.5 0.0 0.00063 19.8 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 GAM23599.1 - 0.028 13.9 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 GAM23599.1 - 0.087 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 HSP70 PF00012.20 GAM23600.1 - 2.7e-260 864.7 8.8 3.1e-260 864.5 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM23600.1 - 6.2e-15 54.8 0.2 2.2e-13 49.7 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GAM23600.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pex19 PF04614.12 GAM23600.1 - 0.0066 16.3 4.0 0.013 15.3 4.0 1.4 1 0 0 1 1 1 1 Pex19 protein family DDR PF08841.10 GAM23600.1 - 0.0074 15.3 0.2 0.093 11.7 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 GAM23600.1 - 0.021 14.3 0.1 6.2 6.2 0.0 2.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 GAM23600.1 - 0.045 13.0 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF1894 PF08979.11 GAM23600.1 - 0.052 13.9 0.0 13 6.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1894) TarH PF02203.15 GAM23600.1 - 0.26 11.2 5.0 0.53 10.2 5.0 1.5 1 0 0 1 1 1 0 Tar ligand binding domain homologue TBCA PF02970.16 GAM23600.1 - 1.1 9.6 12.5 0.42 11.0 9.3 1.9 2 0 0 2 2 2 0 Tubulin binding cofactor A Membralin PF09746.9 GAM23600.1 - 1.7 7.6 3.3 3.1 6.7 3.3 1.3 1 0 0 1 1 1 0 Tumour-associated protein Atg14 PF10186.9 GAM23600.1 - 5.4 6.0 9.0 1.7 7.7 5.9 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Anoctamin PF04547.12 GAM23601.1 - 1e-18 67.5 17.9 3.4e-18 65.7 17.9 1.8 1 1 0 1 1 1 1 Calcium-activated chloride channel TMC PF07810.13 GAM23601.1 - 7.5e-10 39.4 0.0 7.5e-10 39.4 0.0 2.4 2 1 1 3 3 3 1 TMC domain RSN1_7TM PF02714.15 GAM23601.1 - 9.4e-05 21.8 12.8 0.00051 19.5 12.8 2.0 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RRM_1 PF00076.22 GAM23602.1 - 5.7e-83 272.8 0.3 4e-22 77.8 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAM23602.1 - 8e-20 70.8 0.8 4.2e-19 68.5 0.5 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 GAM23602.1 - 5e-11 42.3 0.1 0.003 17.1 0.0 4.3 2 1 3 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM23602.1 - 2.2e-08 33.9 0.1 0.6 10.1 0.0 4.3 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 GAM23602.1 - 3.2e-07 30.3 0.0 0.019 14.9 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAM23602.1 - 2.5e-05 24.3 0.0 4.6 7.4 0.1 4.8 4 1 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 GAM23602.1 - 0.00037 20.5 0.1 4.3 7.4 0.0 3.9 4 0 0 4 4 4 2 RNA binding motif DUF4523 PF15023.6 GAM23602.1 - 0.00051 19.9 0.0 1.1 9.0 0.0 3.4 3 1 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 GAM23602.1 - 0.00064 19.5 0.0 14 5.7 0.0 4.0 4 0 0 4 4 4 1 Occluded RNA-recognition motif SET_assoc PF11767.8 GAM23602.1 - 0.0083 15.8 0.1 4.8 6.9 0.0 4.0 4 0 0 4 4 4 1 Histone lysine methyltransferase SET associated OB_RNB PF08206.11 GAM23602.1 - 0.021 14.5 1.3 32 4.3 0.0 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain MukB_hinge PF16330.5 GAM23602.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 MukB hinge domain RNA12 PF10443.9 GAM23603.1 - 1.9e-10 40.1 0.1 6.9e-07 28.3 0.1 2.5 2 0 0 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 GAM23603.1 - 0.00021 21.3 1.1 0.0043 17.0 0.0 3.3 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 GAM23603.1 - 0.0046 17.4 3.1 1 9.8 0.0 3.6 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) DNA_pol3_theta PF06440.11 GAM23603.1 - 0.0068 16.0 0.5 0.018 14.7 0.5 1.7 1 0 0 1 1 1 1 DNA polymerase III, theta subunit Syntaxin_2 PF14523.6 GAM23603.1 - 0.0095 16.3 1.3 0.039 14.3 1.3 2.1 1 0 0 1 1 1 1 Syntaxin-like protein AAA_22 PF13401.6 GAM23603.1 - 0.019 15.2 0.0 0.075 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM23603.1 - 0.024 14.8 0.0 0.25 11.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 GAM23603.1 - 0.028 14.6 0.0 5.3 7.3 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 GAM23603.1 - 0.028 13.9 0.0 0.67 9.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region M PF02370.16 GAM23603.1 - 0.044 14.3 1.1 0.14 12.8 1.1 1.9 1 0 0 1 1 1 0 M protein repeat AAA_16 PF13191.6 GAM23603.1 - 0.11 12.8 0.1 0.95 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_S10 PF00450.22 GAM23603.1 - 0.12 11.7 1.3 0.42 10.0 0.1 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase eIF3_N PF09440.10 GAM23604.1 - 1.1e-13 51.7 3.9 3e-12 47.1 3.9 2.7 1 1 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 GAM23604.1 - 5.7e-09 36.4 0.8 1.6e-08 35.0 0.2 2.1 2 0 0 2 2 2 1 PCI domain DUF4686 PF15742.5 GAM23604.1 - 0.0066 15.6 0.9 0.0066 15.6 0.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4686) TPR_19 PF14559.6 GAM23604.1 - 0.012 16.2 1.9 2.8 8.5 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fmp27_WPPW PF10359.9 GAM23604.1 - 0.015 14.2 0.2 0.025 13.5 0.2 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TerD PF02342.18 GAM23604.1 - 0.04 13.4 0.3 5.8 6.4 0.1 2.4 2 0 0 2 2 2 0 TerD domain NUDE_C PF04880.13 GAM23604.1 - 0.043 14.3 0.2 0.075 13.5 0.2 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region RPN7 PF10602.9 GAM23604.1 - 0.043 13.5 1.2 4.3 7.0 0.1 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 GAM23604.1 - 0.072 13.4 0.9 5.4 7.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM23604.1 - 0.093 13.0 1.3 7.2 7.1 0.8 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat UbiD PF01977.16 GAM23604.1 - 0.1 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase TPR_14 PF13428.6 GAM23604.1 - 0.19 12.6 0.5 23 6.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM23604.1 - 0.42 10.8 2.4 5.6 7.3 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ATG16 PF08614.11 GAM23604.1 - 0.89 9.8 12.9 4.5 7.4 0.1 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) TPR_6 PF13174.6 GAM23604.1 - 1.5 9.6 5.1 1.9 9.3 1.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAM23604.1 - 6.4 7.2 6.4 22 5.5 1.2 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Arf PF00025.21 GAM23605.1 - 5.8e-40 136.6 0.0 1.9e-39 134.9 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAM23605.1 - 2.8e-10 40.0 0.0 3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM23605.1 - 3.5e-09 36.9 0.0 4.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAM23605.1 - 1e-08 34.7 2.0 6.7e-05 22.2 0.3 2.8 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAM23605.1 - 1.3e-07 31.2 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM23605.1 - 1.8e-07 30.7 0.1 2.9e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM23605.1 - 7.2e-06 26.1 0.1 1.5e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 GAM23605.1 - 0.0072 16.1 0.2 0.014 15.2 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) B_lectin PF01453.24 GAM23606.1 - 5.5e-16 59.0 0.3 0.00019 21.9 0.0 4.1 2 2 2 4 4 4 4 D-mannose binding lectin BofC_C PF08955.10 GAM23606.1 - 0.0016 18.4 0.0 1 9.4 0.0 3.2 3 0 0 3 3 3 2 BofC C-terminal domain AbrB-like PF14250.6 GAM23606.1 - 0.02 15.0 1.8 1 9.5 0.0 3.7 2 2 3 5 5 5 0 AbrB-like transcriptional regulator DAO PF01266.24 GAM23607.1 - 3.5e-37 128.8 0.0 4e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase LBP_C PF17386.2 GAM23607.1 - 0.037 13.9 0.0 0.17 11.8 0.0 2.1 3 0 0 3 3 3 0 Lacto-N-biose phosphorylase C-terminal domain AAA_23 PF13476.6 GAM23608.1 - 1.6e-14 54.9 6.3 1.6e-14 54.9 6.3 3.6 1 1 2 3 3 3 1 AAA domain SMC_N PF02463.19 GAM23608.1 - 3.5e-10 39.7 8.8 1.7e-09 37.5 8.8 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Metallophos PF00149.28 GAM23608.1 - 0.00043 20.8 1.1 0.0009 19.8 0.1 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AAA_21 PF13304.6 GAM23608.1 - 0.00058 19.8 4.9 0.0075 16.1 0.1 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM23608.1 - 0.037 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAM23608.1 - 0.13 12.4 0.3 1.4 9.0 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase DEAD PF00270.29 GAM23608.1 - 0.31 10.8 4.0 9.7 5.9 0.0 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase YjbH PF06082.11 GAM23608.1 - 2.1 7.0 7.3 3.4 6.3 7.3 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Bcr-Abl_Oligo PF09036.10 GAM23608.1 - 3.2 7.8 5.5 8.1 6.5 0.0 3.9 3 1 1 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain ApoO PF09769.9 GAM23608.1 - 3.3 7.7 4.1 7.3 6.6 0.7 2.5 2 0 0 2 2 2 0 Apolipoprotein O ABC_tran PF00005.27 GAM23608.1 - 5.3 7.6 15.3 3.5 8.2 0.1 4.1 3 1 0 3 3 3 0 ABC transporter HTH_3 PF01381.22 GAM23609.1 - 3.3e-14 52.7 0.1 5.6e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 GAM23609.1 - 2.6e-05 24.1 0.1 4.4e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 GAM23609.1 - 0.00014 22.1 0.0 0.00038 20.7 0.0 1.6 1 1 1 2 2 2 1 Helix-turn-helix domain MBF1 PF08523.10 GAM23609.1 - 0.0087 16.5 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_37 PF13744.6 GAM23609.1 - 0.011 15.7 0.2 0.014 15.4 0.2 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 GAM23609.1 - 0.031 14.4 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Ribosomal_L15e PF00827.17 GAM23610.1 - 1.6e-91 305.2 4.6 1.8e-91 305.0 4.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 DPM2 PF07297.12 GAM23611.1 - 3.2e-30 104.2 3.5 3.5e-30 104.1 3.5 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 GAM23611.1 - 0.24 11.3 4.5 0.3 11.0 4.5 1.1 1 0 0 1 1 1 0 PIG-P PH PF00169.29 GAM23612.1 - 2.8e-17 63.1 0.1 5.4e-17 62.2 0.1 1.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 GAM23612.1 - 1.2e-07 32.1 1.2 1.9e-05 25.0 1.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 GAM23612.1 - 3e-06 27.3 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 PH domain HMA PF00403.26 GAM23612.1 - 0.00025 21.4 0.0 0.00038 20.8 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain PH_8 PF15409.6 GAM23612.1 - 0.0009 19.5 0.1 0.0014 18.9 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 GAM23612.1 - 0.0048 17.2 0.0 0.0078 16.5 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 GAM23612.1 - 0.013 15.4 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain ZipA_C PF04354.13 GAM23612.1 - 0.053 13.4 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain FNIP PF05725.12 GAM23615.1 - 7.6e-60 198.8 0.4 4.2e-09 36.4 0.1 8.3 5 2 2 8 8 8 8 FNIP Repeat Asparaginase PF00710.20 GAM23616.1 - 1.1e-64 217.5 0.0 2.6e-64 216.3 0.0 1.6 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 GAM23616.1 - 1.2e-31 109.3 0.0 2.4e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain DUF5535 PF17687.1 GAM23616.1 - 0.034 14.3 0.1 0.69 10.1 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5535) tRNA-synt_1c PF00749.21 GAM23617.1 - 3e-93 312.1 0.0 4.2e-93 311.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF4449 PF14613.6 GAM23617.1 - 0.072 13.2 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DnaJ PF00226.31 GAM23617.1 - 0.092 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain PHP PF02811.19 GAM23618.1 - 4.1e-10 40.2 0.0 4.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 PHP domain TFIIA_gamma_C PF02751.14 GAM23620.1 - 9.5e-24 83.3 2.8 1.6e-23 82.6 2.8 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 GAM23620.1 - 3.2e-22 78.3 0.8 4.5e-22 77.8 0.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Ist1 PF03398.14 GAM23623.1 - 2e-47 161.2 3.8 2.6e-47 160.8 3.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway LydB PF16084.5 GAM23623.1 - 0.053 13.3 0.0 0.18 11.6 0.0 1.8 1 1 1 2 2 2 0 LydA-holin antagonist Gag_p19 PF02228.16 GAM23623.1 - 0.078 13.4 0.3 17 6.0 0.0 2.4 2 0 0 2 2 2 0 Major core protein p19 ABC_tran PF00005.27 GAM23624.1 - 2.6e-56 189.9 0.2 1.3e-26 93.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAM23624.1 - 1.7e-18 67.5 7.1 2.7e-07 30.7 0.9 4.5 2 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 GAM23624.1 - 3.9e-12 46.0 6.1 1.2e-10 41.3 1.6 2.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 GAM23624.1 - 2.1e-10 40.4 3.2 0.00012 21.6 0.2 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM23624.1 - 8.3e-08 31.9 2.0 0.0022 17.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 GAM23624.1 - 1.7e-06 28.6 0.6 0.018 15.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GAM23624.1 - 1.8e-05 25.2 0.0 0.23 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 GAM23624.1 - 1.9e-05 24.7 0.1 0.054 13.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.6 GAM23624.1 - 0.00025 21.2 4.7 9.9 6.5 0.0 4.7 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 GAM23624.1 - 0.0003 20.7 0.5 0.53 10.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 GAM23624.1 - 0.00035 20.8 0.0 0.81 9.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAM23624.1 - 0.00057 20.2 0.3 0.34 11.2 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.6 GAM23624.1 - 0.00061 20.3 21.4 0.00088 19.8 0.2 3.9 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAM23624.1 - 0.00071 18.8 0.0 0.37 9.9 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 GAM23624.1 - 0.00079 19.4 0.2 1.5 8.7 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 GAM23624.1 - 0.0011 19.2 0.6 0.35 11.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 GAM23624.1 - 0.0018 18.5 2.7 0.39 10.8 0.1 3.8 4 0 0 4 4 4 1 Helicase HerA, central domain AAA PF00004.29 GAM23624.1 - 0.0025 18.2 0.2 1.5 9.2 0.0 3.5 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 GAM23624.1 - 0.0028 16.4 1.3 2.4 6.7 0.1 3.6 3 2 0 4 4 4 1 AAA domain AAA_15 PF13175.6 GAM23624.1 - 0.0034 17.2 12.0 0.016 15.0 0.7 2.9 4 0 0 4 4 3 2 AAA ATPase domain RNA_helicase PF00910.22 GAM23624.1 - 0.0035 17.7 0.1 4.8 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 GAM23624.1 - 0.0036 17.0 0.7 2.4 7.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 GAM23624.1 - 0.0075 16.3 0.0 5.9 6.9 0.0 3.4 4 0 0 4 4 3 0 AAA domain MeaB PF03308.16 GAM23624.1 - 0.0096 14.9 0.1 1.6 7.7 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 GAM23624.1 - 0.0099 15.9 0.0 0.61 10.1 0.0 2.7 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.12 GAM23624.1 - 0.011 15.0 0.1 1.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin G-alpha PF00503.20 GAM23624.1 - 0.014 14.5 0.2 0.5 9.5 0.1 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_30 PF13604.6 GAM23624.1 - 0.022 14.5 0.0 8.9 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 GAM23624.1 - 0.024 14.2 0.1 28 4.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 GAM23624.1 - 0.025 14.5 0.3 4.9 7.0 0.0 3.7 3 1 0 3 3 3 0 NTPase Roc PF08477.13 GAM23624.1 - 0.027 14.7 0.8 9.4 6.5 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MukB PF04310.12 GAM23624.1 - 0.035 13.9 0.2 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal KAP_NTPase PF07693.14 GAM23624.1 - 0.04 13.2 0.3 5.4 6.2 0.0 2.5 2 1 0 3 3 2 0 KAP family P-loop domain DUF815 PF05673.13 GAM23624.1 - 0.047 12.8 0.1 1.1 8.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_27 PF13514.6 GAM23624.1 - 0.053 13.1 0.5 2.4 7.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 GAM23624.1 - 0.059 13.3 0.9 2 8.3 0.0 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 GAM23624.1 - 0.06 13.3 0.1 15 5.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 GAM23624.1 - 0.069 12.7 0.5 6.1 6.4 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 GAM23624.1 - 0.1 11.9 0.5 12 5.2 0.0 2.8 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Adeno_IVa2 PF02456.15 GAM23624.1 - 0.11 11.3 0.1 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein Ploopntkinase3 PF18751.1 GAM23624.1 - 0.11 12.4 0.1 8.4 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Cytidylate_kin PF02224.18 GAM23624.1 - 0.14 11.9 0.1 8.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Rad17 PF03215.15 GAM23624.1 - 0.14 12.0 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain CLP1_P PF16575.5 GAM23624.1 - 0.15 11.9 0.1 14 5.4 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 GAM23624.1 - 0.16 11.7 0.0 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 GAM23624.1 - 0.43 11.0 2.9 27 5.2 0.1 3.3 3 1 0 3 3 2 0 AAA domain Nup160 PF11715.8 GAM23625.1 - 1e-32 113.5 5.4 2.9e-32 112.0 5.4 1.8 1 1 0 1 1 1 1 Nucleoporin Nup120/160 CcmE PF03100.15 GAM23625.1 - 1.3e-10 41.4 0.1 3.2e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 CcmE TPR_1 PF00515.28 GAM23625.1 - 0.0011 18.6 0.4 0.39 10.6 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat PFU PF09070.11 GAM23625.1 - 0.015 15.6 0.2 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 PFU (PLAA family ubiquitin binding) TPR_7 PF13176.6 GAM23625.1 - 0.022 14.8 0.1 12 6.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM23625.1 - 0.044 14.1 0.0 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM23625.1 - 0.056 13.7 1.6 0.35 11.1 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAM23625.1 - 0.096 12.9 1.9 0.92 9.9 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_45 PF14947.6 GAM23625.1 - 0.26 11.3 3.2 0.48 10.5 0.6 2.9 2 0 0 2 2 2 0 Winged helix-turn-helix PPR PF01535.20 GAM23625.1 - 0.87 10.0 2.9 8.8 6.8 0.1 3.6 4 0 0 4 4 4 0 PPR repeat RasGEF PF00617.19 GAM23627.1 - 2.9e-52 177.4 1.3 5.8e-52 176.5 1.3 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM23627.1 - 2.7e-20 72.5 0.5 2.7e-20 72.5 0.5 2.9 3 0 0 3 3 3 1 RasGEF N-terminal motif AA_kinase PF00696.28 GAM23628.1 - 3.8e-43 147.8 0.1 4.4e-43 147.6 0.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family Rep-A_N PF04057.12 GAM23628.1 - 0.07 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain DUF1712 PF08217.11 GAM23629.1 - 2.3e-62 211.4 13.1 4.9e-51 174.0 7.7 3.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) Peptidase_M8 PF01457.16 GAM23630.1 - 1.5e-75 254.9 8.5 1.9e-75 254.6 8.5 1.1 1 0 0 1 1 1 1 Leishmanolysin Frataxin_Cyay PF01491.16 GAM23631.1 - 1.4e-33 115.2 0.0 1.7e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain ILEI PF15711.5 GAM23632.1 - 6.3e-12 45.8 0.0 1e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Interleukin-like EMT inducer SRP9-21 PF05486.12 GAM23635.1 - 4.6e-08 33.3 1.7 2.2e-06 28.0 1.7 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) MitMem_reg PF13012.6 GAM23636.1 - 3.4e-24 85.4 0.4 6.6e-24 84.5 0.4 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAM23636.1 - 5.9e-22 77.9 0.0 9.5e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RRM_1 PF00076.22 GAM23637.1 - 4.8e-24 84.0 0.0 2.6e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 GAM23637.1 - 3.6e-18 65.3 0.8 3.6e-18 65.3 0.8 2.4 2 0 0 2 2 2 1 Surp module CTD_bind PF04818.13 GAM23637.1 - 2.1e-12 47.6 0.0 1.1e-11 45.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_5 PF13893.6 GAM23637.1 - 1.8e-07 30.8 0.0 0.00025 20.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM23637.1 - 1.2e-06 28.2 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif CTK3 PF12243.8 GAM23637.1 - 2.5e-06 27.5 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 RRM_3 PF08777.11 GAM23637.1 - 0.00018 21.5 0.0 0.038 14.0 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif NnrS PF05940.12 GAM23638.1 - 0.00014 21.3 3.5 0.00017 21.1 3.5 1.1 1 0 0 1 1 1 1 NnrS protein Tetraspanin PF00335.20 GAM23638.1 - 0.0031 17.2 8.3 0.0059 16.3 8.4 1.5 1 1 0 1 1 1 1 Tetraspanin family FAM70 PF14967.6 GAM23638.1 - 0.0071 15.8 1.8 0.01 15.3 1.8 1.2 1 0 0 1 1 1 1 FAM70 protein DUF2892 PF11127.8 GAM23638.1 - 0.045 13.8 3.6 0.045 13.8 3.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) FeoB_associated PF12669.7 GAM23638.1 - 0.092 13.2 0.5 0.092 13.2 0.5 2.6 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein TMCCDC2 PF15844.5 GAM23638.1 - 0.3 11.0 3.9 0.2 11.6 2.3 1.5 1 1 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 SUR7 PF06687.12 GAM23638.1 - 0.52 9.9 6.6 0.62 9.7 6.6 1.2 1 0 0 1 1 1 0 SUR7/PalI family PrgI PF12666.7 GAM23638.1 - 9.8 7.0 10.4 31 5.3 8.3 2.3 1 1 1 2 2 2 0 PrgI family protein AAA_16 PF13191.6 GAM23639.1 - 0.068 13.6 0.1 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain STATa_Ig PF18214.1 GAM23640.1 - 1.1e-48 164.2 1.7 1.1e-48 164.2 1.7 1.7 2 0 0 2 2 2 1 STATa Immunoglobulin-like domain EF-hand_12 PF17901.1 GAM23640.1 - 9.7e-40 134.9 0.8 2.4e-39 133.6 0.8 1.7 1 0 0 1 1 1 1 EF-hand fold domain Dict-STAT-coil PF09267.10 GAM23640.1 - 3.6e-28 98.2 10.6 3.6e-28 98.2 10.6 2.2 2 1 0 2 2 2 1 Dictyostelium STAT, coiled coil SH2 PF00017.24 GAM23640.1 - 4.4e-12 45.9 0.0 1e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 GAM23640.1 - 0.025 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 SH2 domain Cbl_N3 PF02762.14 GAM23640.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain DUF2457 PF10446.9 GAM23641.1 - 1.5 7.9 24.3 2.8 7.0 24.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) YjbH PF06082.11 GAM23641.1 - 2.7 6.7 24.5 3.2 6.5 24.5 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Atrophin-1 PF03154.15 GAM23641.1 - 8.3 4.6 45.4 10 4.2 45.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family dUTPase PF00692.19 GAM23642.1 - 4.8e-10 39.2 0.0 1.3e-07 31.4 0.0 2.1 1 1 1 2 2 2 2 dUTPase DCD PF06559.11 GAM23642.1 - 0.00039 19.3 0.0 0.23 10.2 0.0 2.0 1 1 1 2 2 2 2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Ig_mannosidase PF17753.1 GAM23642.1 - 0.015 15.0 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Ig-fold domain Mgm101p PF06420.12 GAM23643.1 - 1.6e-74 249.1 0.0 2.3e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Cellulose_synt PF03552.14 GAM23644.1 - 5.4e-23 81.4 11.7 2.5e-14 52.8 1.3 3.9 3 1 1 4 4 4 3 Cellulose synthase Glyco_trans_2_3 PF13632.6 GAM23644.1 - 1.2e-22 80.8 0.1 1.2e-22 80.8 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAM23644.1 - 1.4e-15 57.8 0.0 4.3e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAM23644.1 - 2.1e-10 40.7 0.0 2.6e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAM23644.1 - 1.1e-07 31.6 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Pkinase PF00069.25 GAM23645.1 - 5.7e-65 219.3 0.0 1.2e-64 218.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM23645.1 - 1.8e-46 158.5 0.0 3.3e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAM23645.1 - 3.5e-08 33.7 0.2 1.4e-07 31.8 0.2 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain CH PF00307.31 GAM23645.1 - 7e-08 32.6 1.6 1.1e-07 32.0 0.1 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain C1_1 PF00130.22 GAM23645.1 - 1.2e-07 31.5 4.7 2.3e-07 30.6 4.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SBF2 PF12335.8 GAM23645.1 - 1e-06 28.6 0.8 1e-06 28.6 0.8 2.3 2 0 0 2 2 2 1 Myotubularin protein Kinase-like PF14531.6 GAM23645.1 - 0.0018 17.7 0.0 0.0084 15.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Fez1 PF06818.15 GAM23645.1 - 0.09 13.2 10.4 1.6 9.2 4.3 2.5 2 0 0 2 2 2 0 Fez1 PHD_4 PF16866.5 GAM23645.1 - 0.12 12.5 1.5 0.39 10.8 1.5 1.9 1 0 0 1 1 1 0 PHD-finger TMCO5 PF14992.6 GAM23645.1 - 0.47 10.0 11.9 1.6 8.2 8.7 2.9 2 1 1 3 3 3 0 TMCO5 family DivIVA PF05103.13 GAM23645.1 - 0.49 10.5 7.4 2 8.5 0.3 2.4 2 0 0 2 2 2 0 DivIVA protein PHD PF00628.29 GAM23645.1 - 0.71 9.8 4.0 1.7 8.6 4.0 1.6 1 0 0 1 1 1 0 PHD-finger DUF4763 PF15960.5 GAM23645.1 - 1.6 8.0 15.0 0.95 8.7 8.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4763) GAS PF13851.6 GAM23645.1 - 3.9 6.8 14.1 3.4 7.0 5.2 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FliJ PF02050.16 GAM23645.1 - 4.8 7.4 10.4 0.37 11.0 0.6 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein DivIC PF04977.15 GAM23645.1 - 4.8 7.0 8.3 8.3 6.3 1.1 2.8 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 GAM23645.1 - 5.9 7.6 10.5 12 6.6 1.7 2.8 2 0 0 2 2 2 0 SlyX GHL15 PF14885.6 GAM23646.1 - 5.4e-19 69.2 3.6 5.4e-19 69.2 3.6 1.5 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase family 15 DEC-1_N PF04625.13 GAM23646.1 - 0.34 9.9 3.4 0.48 9.4 3.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SdrD_B PF17210.3 GAM23647.1 - 4.6e-12 46.1 13.7 0.00012 22.2 0.6 7.8 7 1 1 8 8 8 4 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM23647.1 - 9e-06 25.9 0.1 0.025 14.8 0.0 7.9 6 1 0 6 6 6 4 Carboxypeptidase regulatory-like domain Y_Y_Y PF07495.13 GAM23647.1 - 0.002 18.0 2.8 13 5.9 0.1 4.4 4 0 0 4 4 4 2 Y_Y_Y domain Pox_RNA_pol PF03293.14 GAM23647.1 - 0.027 14.2 0.1 34 4.1 0.0 3.7 3 0 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Telomerase_RBD PF12009.8 GAM23648.1 - 1.2e-13 51.4 11.1 2e-11 44.1 7.7 3.5 2 1 0 2 2 2 2 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 GAM23648.1 - 8.9e-13 48.3 0.9 7.7e-09 35.4 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) COX6C PF02937.15 GAM23649.1 - 0.0092 16.1 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc DUF3951 PF13131.6 GAM23649.1 - 0.11 12.7 1.5 0.4 10.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) zf-TRAF PF02176.18 GAM23650.1 - 5.1e-11 43.1 7.1 5.1e-11 43.1 7.1 3.9 2 2 2 4 4 4 2 TRAF-type zinc finger MATH PF00917.26 GAM23650.1 - 2e-07 31.2 0.1 2e-07 31.2 0.1 2.5 3 1 0 3 3 3 1 MATH domain zf-C3HC4_2 PF13923.6 GAM23650.1 - 6.3e-06 25.9 11.1 6.3e-06 25.9 11.1 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM23650.1 - 7.6e-05 23.0 9.3 7.6e-05 23.0 9.3 4.0 3 1 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 GAM23650.1 - 0.00025 21.0 7.1 0.00025 21.0 7.1 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAM23650.1 - 0.001 19.2 10.2 0.001 19.2 10.2 3.3 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-TRAF_2 PF15965.5 GAM23650.1 - 0.0047 17.4 8.0 0.0047 17.4 8.0 3.3 1 1 2 3 3 3 2 TRAF-like zinc-finger PKcGMP_CC PF16808.5 GAM23650.1 - 0.019 14.8 0.9 0.041 13.7 0.4 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RasGEF PF00617.19 GAM23651.1 - 1.3e-54 185.1 2.6 1.3e-54 185.1 2.6 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM23651.1 - 1.4e-16 60.6 0.3 1.4e-16 60.6 0.3 2.8 4 0 0 4 4 4 1 RasGEF N-terminal motif FERM_f0 PF16511.5 GAM23651.1 - 7e-12 45.5 0.0 0.0046 17.2 0.0 3.9 3 0 0 3 3 3 3 N-terminal or F0 domain of Talin-head FERM YukD PF08817.10 GAM23651.1 - 8e-06 26.5 0.0 0.042 14.6 0.0 3.0 2 0 0 2 2 2 2 WXG100 protein secretion system (Wss), protein YukD FERM_N PF09379.10 GAM23651.1 - 5e-05 23.2 0.0 0.04 13.9 0.0 3.3 3 0 0 3 3 3 1 FERM N-terminal domain ubiquitin PF00240.23 GAM23651.1 - 0.00089 19.0 0.0 26 4.7 0.0 4.9 5 0 0 5 5 5 0 Ubiquitin family RA PF00788.23 GAM23651.1 - 0.0026 18.3 0.0 4.6 7.9 0.0 3.9 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Rad60-SLD PF11976.8 GAM23651.1 - 0.019 14.8 1.0 5.7 6.8 0.0 4.6 6 0 0 6 6 6 0 Ubiquitin-2 like Rad60 SUMO-like Ras_bdg_2 PF14847.6 GAM23651.1 - 0.046 14.1 0.1 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 Ras-binding domain of Byr2 PQ-loop PF04193.14 GAM23653.1 - 2.7e-09 36.6 1.8 2.7e-09 36.6 1.8 2.4 2 0 0 2 2 2 1 PQ loop repeat UDG PF03167.19 GAM23654.1 - 1e-18 67.8 0.0 1.9e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ANAPC8 PF04049.13 GAM23654.1 - 7.4 6.6 0.0 7.4 6.6 0.0 3.4 3 1 0 3 3 3 0 Anaphase promoting complex subunit 8 / Cdc23 tRNA-synt_2 PF00152.20 GAM23655.1 - 5.8e-46 157.0 0.6 8.1e-46 156.5 0.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Ion_trans_N PF08412.10 GAM23655.1 - 0.013 15.1 0.3 0.029 14.0 0.3 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal tRNA-synt_2d PF01409.20 GAM23655.1 - 0.064 12.7 0.8 9.3 5.6 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Amidohydro_2 PF04909.14 GAM23656.1 - 9.1e-17 61.8 0.0 1.4e-16 61.2 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase Consortin_C PF15281.6 GAM23656.1 - 0.055 13.5 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Consortin C-terminus LRR_6 PF13516.6 GAM23656.1 - 0.18 11.9 0.0 0.53 10.5 0.0 1.8 1 0 0 1 1 1 0 Leucine Rich repeat tRNA-synt_2 PF00152.20 GAM23657.1 - 4.1e-75 252.8 0.1 6.1e-75 252.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAM23657.1 - 4.5e-07 29.8 0.1 8e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAM23657.1 - 0.00039 20.0 1.6 0.9 9.0 0.2 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Roughex PF06020.11 GAM23657.1 - 0.27 10.3 4.3 0.53 9.3 4.3 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Complex1_LYR PF05347.15 GAM23658.1 - 7.2e-15 54.8 0.2 9.9e-15 54.3 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAM23658.1 - 1.4e-05 25.7 0.6 1.7e-05 25.5 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 GAM23658.1 - 0.0045 17.6 0.0 0.0054 17.3 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Pkinase PF00069.25 GAM23659.1 - 3e-67 226.8 0.0 4.4e-67 226.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM23659.1 - 2.6e-46 158.0 0.0 4e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM23659.1 - 8.3e-06 24.8 0.8 4e-05 22.6 0.0 2.2 2 1 1 3 3 3 1 Fungal protein kinase APH PF01636.23 GAM23659.1 - 0.00043 20.3 0.0 0.016 15.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM23659.1 - 0.0088 15.0 0.1 0.023 13.7 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM23659.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 GAM23659.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lung_7-TM_R PF06814.13 GAM23660.1 - 4.9e-09 35.8 13.5 4.9e-09 35.8 13.5 2.3 2 0 0 2 2 2 1 Lung seven transmembrane receptor NmrA PF05368.13 GAM23661.1 - 8.2e-22 77.9 0.4 2.8e-20 72.9 0.4 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM23661.1 - 8.5e-08 32.3 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM23661.1 - 7e-05 22.0 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family EB PF01683.18 GAM23662.1 - 0.0016 18.7 64.2 0.0031 17.8 9.1 6.4 2 2 4 6 6 6 5 EB module Colipase PF01114.18 GAM23662.1 - 0.034 13.8 1.1 0.034 13.8 1.1 4.6 2 1 2 4 4 4 0 Colipase, N-terminal domain FNIP PF05725.12 GAM23663.1 - 6.3e-118 384.8 29.8 4.3e-14 52.4 0.4 10.1 2 2 12 15 15 15 15 FNIP Repeat T2SSM_b PF10741.9 GAM23664.1 - 0.13 12.1 0.0 0.91 9.4 0.0 1.9 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DDE_Tnp_4 PF13359.6 GAM23665.1 - 5.9e-15 55.3 0.2 1.8e-13 50.5 0.2 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM23665.1 - 5.1e-05 23.0 2.6 8e-05 22.4 2.6 1.4 1 1 0 1 1 1 1 Transposase DDE domain HD_2 PF12917.7 GAM23666.1 - 0.0063 16.3 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Ank_2 PF12796.7 GAM23669.1 - 8.9e-05 23.0 0.3 1.6 9.4 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM23669.1 - 0.045 14.3 0.0 3.5e+02 2.4 0.0 5.5 5 0 0 5 5 5 0 Ankyrin repeat SPT6_acidic PF14632.6 GAM23670.1 - 0.22 12.1 8.5 2.2 8.9 2.7 2.1 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Oxidored_FMN PF00724.20 GAM23671.1 - 3.5e-73 246.8 0.0 4.1e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 GAM23671.1 - 0.0079 15.3 0.0 0.017 14.2 0.0 1.5 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF620 PF04788.12 GAM23671.1 - 0.077 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF620) Lipase_3 PF01764.25 GAM23672.1 - 4.1e-31 107.8 0.0 5.3e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GAM23672.1 - 0.00012 21.7 0.0 0.0084 15.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) PGAP1 PF07819.13 GAM23672.1 - 0.0057 16.4 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAM23672.1 - 0.076 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 GAM23672.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 GAM23673.1 - 5.6e-28 97.6 0.0 8e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GAM23673.1 - 7.9e-06 25.6 0.0 1.8e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.14 GAM23673.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) FERM_N PF09379.10 GAM23674.1 - 0.04 13.9 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 FERM N-terminal domain TIG PF01833.24 GAM23675.1 - 1.5e-10 41.0 22.4 3.2e-07 30.3 3.4 3.8 4 0 0 4 4 4 3 IPT/TIG domain RasGEF PF00617.19 GAM23676.1 - 2.1e-34 119.2 0.7 3.7e-34 118.5 0.1 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM23676.1 - 1.4e-19 70.3 0.4 4.2e-19 68.7 0.4 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Ecm29 PF13001.7 GAM23676.1 - 0.014 14.2 0.3 0.02 13.6 0.3 1.1 1 0 0 1 1 1 0 Proteasome stabiliser Pox_D5 PF03288.16 GAM23676.1 - 0.39 11.2 2.4 0.72 10.4 0.2 2.3 2 1 0 2 2 2 0 Poxvirus D5 protein-like Lyase_1 PF00206.20 GAM23677.1 - 6.6e-51 173.6 0.0 8.8e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 GAM23677.1 - 8.7e-46 154.7 0.3 2e-45 153.6 0.1 1.8 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal RasGEF PF00617.19 GAM23678.1 - 2.2e-42 145.2 0.8 4.9e-42 144.1 0.2 1.9 2 0 0 2 2 2 1 RasGEF domain GRAM PF02893.20 GAM23678.1 - 3.7e-16 59.0 0.1 1.2e-15 57.4 0.1 1.9 1 0 0 1 1 1 1 GRAM domain RhoGAP PF00620.27 GAM23678.1 - 7.6e-08 32.3 0.3 2.8e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain RasGEF_N PF00618.20 GAM23678.1 - 0.00046 20.4 0.1 0.00046 20.4 0.1 2.8 3 0 0 3 3 3 1 RasGEF N-terminal motif CMV_1a PF12467.8 GAM23678.1 - 1 9.7 3.5 0.97 9.8 0.0 2.4 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Ank_2 PF12796.7 GAM23679.1 - 0.00011 22.7 0.1 0.0046 17.5 0.0 3.3 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM23679.1 - 0.0094 16.4 0.1 15 6.5 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 GAM23679.1 - 0.035 14.7 0.2 1.7 9.3 0.0 3.7 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM23679.1 - 0.041 14.2 0.0 0.18 12.1 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) WD40 PF00400.32 GAM23680.1 - 4.5e-19 68.4 3.1 9.8e-06 26.2 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM23680.1 - 4.4e-07 30.1 0.0 3.2 8.1 0.2 4.4 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain NUP214 PF16755.5 GAM23680.1 - 0.0001 21.7 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Nup160 PF11715.8 GAM23680.1 - 0.0012 17.6 2.5 0.36 9.4 0.0 3.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 GAM23680.1 - 0.009 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Myb_DNA-binding PF00249.31 GAM23682.1 - 4.1e-05 23.7 0.3 0.00018 21.6 0.0 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain SOBP PF15279.6 GAM23682.1 - 0.00018 22.2 41.5 0.00018 22.2 41.5 4.3 1 1 2 4 4 4 1 Sine oculis-binding protein 7tm_2 PF00002.24 GAM23683.1 - 0.0013 18.0 9.9 0.0013 18.0 9.9 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) UL45 PF05473.12 GAM23683.1 - 0.37 10.4 2.5 0.29 10.7 0.3 1.9 2 1 1 3 3 3 0 UL45 protein, carbohydrate-binding C-type lectin-like GPR_Gpa2_C PF11970.8 GAM23683.1 - 6.4 6.9 9.2 0.23 11.6 2.2 2.3 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term FNIP PF05725.12 GAM23684.1 - 2.9e-56 187.4 17.6 2.8e-12 46.6 0.1 8.5 5 2 3 8 8 8 7 FNIP Repeat Ribosomal_60s PF00428.19 GAM23685.1 - 1.7e-23 83.0 16.5 2e-23 82.8 16.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DSPc PF00782.20 GAM23686.1 - 1.8e-28 99.0 0.0 2.7e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM23686.1 - 0.00011 21.9 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 GAM23686.1 - 0.0014 18.9 0.1 0.0097 16.2 0.1 2.1 2 1 0 2 2 2 1 Rit1 DUSP-like domain Glyco_hydro_30C PF17189.4 GAM23686.1 - 0.089 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain G-alpha PF00503.20 GAM23687.1 - 3.6e-105 352.0 2.3 4.9e-105 351.6 2.3 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM23687.1 - 2.7e-16 59.5 2.4 2.2e-12 46.8 0.8 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAM23687.1 - 6.6e-06 26.3 0.2 0.025 14.8 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAM23687.1 - 2.6e-05 23.7 0.5 0.021 14.2 0.3 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Ras PF00071.22 GAM23687.1 - 0.00077 19.1 0.6 0.096 12.3 0.2 2.8 2 1 0 2 2 2 1 Ras family AAA_24 PF13479.6 GAM23687.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAM23687.1 - 0.1 12.7 0.0 12 6.0 0.1 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase Sigma54_activat PF00158.26 GAM23687.1 - 0.15 11.8 0.2 0.71 9.6 0.1 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 GAM23687.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Forkhead PF00250.18 GAM23689.1 - 0.0027 17.9 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 Forkhead domain Phage_holin_2_1 PF04971.12 GAM23690.1 - 0.099 12.7 0.6 0.27 11.3 0.6 1.7 1 0 0 1 1 1 0 Bacteriophage P21 holin S MinE PF03776.14 GAM23691.1 - 0.015 15.3 0.0 0.047 13.7 0.0 1.8 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE DUF5643 PF18705.1 GAM23691.1 - 1.1 9.3 6.5 0.15 12.0 1.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5643) DUF2072 PF09845.9 GAM23691.1 - 2.7 8.2 6.5 2.1 8.6 0.6 2.8 3 0 0 3 3 3 0 Zn-ribbon containing protein Mak16 PF04874.14 GAM23691.1 - 9.5 6.9 6.9 25 5.5 0.3 2.5 2 0 0 2 2 2 0 Mak16 protein C-terminal region Glyco_hydro_25 PF01183.20 GAM23692.1 - 2.4e-12 47.4 0.0 2.6e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Glyco_hydro_25 PF01183.20 GAM23693.1 - 3.1e-12 47.1 0.1 3.4e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 SOBP PF15279.6 GAM23694.1 - 0.86 10.2 27.5 1 9.9 17.8 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein TFIIA PF03153.13 GAM23694.1 - 2 8.3 60.2 0.13 12.2 47.3 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nop25 PF09805.9 GAM23694.1 - 5.1 7.6 25.2 5 7.6 4.3 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) RVT_3 PF13456.6 GAM23695.1 - 1.3 8.9 4.6 4.4 7.1 0.1 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like Ndc80_HEC PF03801.13 GAM23697.1 - 1.8e-39 134.9 0.9 1.8e-39 134.9 0.9 3.7 3 2 0 3 3 3 1 HEC/Ndc80p family UPF0242 PF06785.11 GAM23697.1 - 0.00015 22.0 25.0 0.00015 22.0 25.0 3.2 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 GAM23697.1 - 0.015 15.5 24.5 0.015 15.5 24.5 3.9 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Ank_4 PF13637.6 GAM23698.1 - 1.2e-37 127.7 3.7 9.8e-05 22.8 0.0 9.6 7 1 3 10 10 10 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM23698.1 - 8e-31 106.5 10.4 4.4e-07 30.4 0.4 6.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM23698.1 - 4e-28 97.1 5.1 0.0041 17.4 0.0 10.5 4 3 7 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM23698.1 - 2.6e-16 58.1 0.7 2.2 9.1 0.0 12.1 12 1 1 13 13 13 2 Ankyrin repeat Ank PF00023.30 GAM23698.1 - 2.5e-07 30.8 2.0 48 4.6 0.0 9.6 7 4 2 9 9 9 0 Ankyrin repeat DUF5049 PF16468.5 GAM23698.1 - 3.9e-07 29.9 0.2 5.1 7.1 0.0 7.3 6 1 4 10 10 10 2 Domain of unknown function (DUF5049) DUF3447 PF11929.8 GAM23698.1 - 6.5e-07 29.2 1.1 0.93 9.5 0.0 5.1 3 2 1 5 5 5 2 Domain of unknown function (DUF3447) SH3BGR PF04908.15 GAM23699.1 - 3e-08 33.7 0.1 3.3e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 GAM23699.1 - 6.7e-08 32.6 0.0 9.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin RhoGAP PF00620.27 GAM23700.1 - 4.9e-35 120.6 0.1 1.2e-34 119.4 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain BAR_3 PF16746.5 GAM23700.1 - 3.7e-15 56.3 2.7 1e-14 54.9 2.7 1.8 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 GAM23700.1 - 4e-06 26.7 2.5 7e-06 25.9 2.5 1.4 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 GAM23700.1 - 0.0043 16.2 5.2 0.16 11.0 4.1 2.4 1 1 1 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking Arfaptin PF06456.13 GAM23700.1 - 0.013 15.1 0.8 0.013 15.1 0.8 1.6 2 0 0 2 2 2 0 Arfaptin-like domain Nod1 PF17114.5 GAM23700.1 - 0.02 15.0 0.1 0.052 13.7 0.1 1.7 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 DUF778 PF05608.12 GAM23700.1 - 0.091 13.1 2.3 6.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF778) DUF2796 PF10986.8 GAM23700.1 - 5.8 6.8 20.9 1.1e+02 2.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) CNOT11 PF10155.9 GAM23701.1 - 1.3e-44 151.4 6.4 3.6e-44 149.9 6.4 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 SUIM_assoc PF16619.5 GAM23701.1 - 1.2 9.3 27.4 1.6 8.8 9.9 3.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Ammonium_transp PF00909.21 GAM23702.1 - 1.7e-62 211.4 13.8 5.1e-58 196.7 11.6 2.9 1 1 1 2 2 2 2 Ammonium Transporter Family FNIP PF05725.12 GAM23703.1 - 1.1e-73 243.2 33.5 1.3e-14 54.1 2.4 9.6 4 3 3 9 9 9 9 FNIP Repeat SIR2_2 PF13289.6 GAM23704.1 - 0.027 14.6 0.1 0.06 13.5 0.1 1.5 1 0 0 1 1 1 0 SIR2-like domain FNIP PF05725.12 GAM23705.1 - 1.6e-103 338.6 58.5 8.5e-14 51.4 5.1 11.3 8 3 2 11 11 11 10 FNIP Repeat ZapB PF06005.12 GAM23705.1 - 0.019 15.4 3.1 0.043 14.3 3.1 1.6 1 0 0 1 1 1 0 Cell division protein ZapB SKA2 PF16740.5 GAM23705.1 - 0.069 12.9 0.2 0.19 11.5 0.2 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DHR10 PF18595.1 GAM23705.1 - 0.2 11.7 2.4 0.35 10.9 2.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain LRR_4 PF12799.7 GAM23705.1 - 0.59 10.6 18.6 4.1 8.0 0.6 7.0 6 1 2 8 8 8 0 Leucine Rich repeats (2 copies) DivIC PF04977.15 GAM23705.1 - 1.8 8.4 3.6 6.5 6.6 3.5 1.9 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 GAM23705.1 - 2.7 8.1 8.2 11 6.2 1.5 2.5 1 1 1 2 2 2 0 Basic region leucine zipper RmlD_sub_bind PF04321.17 GAM23706.1 - 7.9e-54 182.7 0.0 9.4e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 GAM23706.1 - 2.8e-20 72.8 0.0 3.8e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM23706.1 - 2.8e-12 46.4 0.0 1.2e-11 44.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAM23706.1 - 7.4e-11 42.0 0.1 1.2e-10 41.4 0.1 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAM23706.1 - 5.7e-06 25.5 0.1 8.6e-06 24.9 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAM23706.1 - 7e-06 25.4 0.0 0.00041 19.6 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.25 GAM23706.1 - 0.02 14.3 0.0 0.055 12.9 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase FNIP PF05725.12 GAM23707.1 - 8.6e-104 339.5 35.5 9.2e-14 51.3 0.1 12.4 5 2 7 14 14 14 14 FNIP Repeat ZapB PF06005.12 GAM23707.1 - 0.031 14.7 6.6 0.066 13.7 6.6 1.5 1 0 0 1 1 1 0 Cell division protein ZapB UPF0242 PF06785.11 GAM23707.1 - 0.061 13.4 5.1 0.063 13.4 3.8 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MAD PF05557.13 GAM23707.1 - 0.13 10.6 5.3 0.18 10.1 5.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Ead_Ea22 PF13935.6 GAM23707.1 - 0.16 12.6 1.5 0.28 11.8 1.5 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein LRR_4 PF12799.7 GAM23707.1 - 0.2 12.1 21.1 3.5 8.2 0.1 7.3 3 3 6 9 9 9 0 Leucine Rich repeats (2 copies) SlyX PF04102.12 GAM23707.1 - 0.36 11.5 3.4 1.1 9.9 2.9 2.1 2 0 0 2 2 2 0 SlyX Cep57_CLD_2 PF14197.6 GAM23707.1 - 0.41 10.8 8.1 0.89 9.7 8.1 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 GAM23707.1 - 0.71 9.7 8.7 0.95 9.3 2.2 2.3 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 GAM23707.1 - 4.9 7.3 6.4 24 5.1 6.0 2.1 1 1 1 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 GAM23707.1 - 5 7.6 5.4 10 6.5 5.4 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) bZIP_2 PF07716.15 GAM23707.1 - 7.9 6.7 13.3 8.8 6.5 2.2 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Acyl_transf_3 PF01757.22 GAM23708.1 - 1.4e-10 40.8 34.3 1.7e-10 40.5 34.3 1.1 1 0 0 1 1 1 1 Acyltransferase family FNIP PF05725.12 GAM23709.1 - 1.1e-73 243.1 30.4 6.7e-12 45.4 0.1 10.8 6 2 6 12 12 12 12 FNIP Repeat Tho2 PF11262.8 GAM23709.1 - 0.0089 15.3 2.7 0.017 14.3 2.7 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Macoilin PF09726.9 GAM23709.1 - 0.011 14.4 6.3 0.014 14.0 6.3 1.1 1 0 0 1 1 1 0 Macoilin family PikAIV_N PF18605.1 GAM23709.1 - 0.17 11.5 9.7 0.57 9.8 0.3 2.6 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain AAA_23 PF13476.6 GAM23709.1 - 0.17 12.4 6.8 0.24 11.9 6.8 1.3 1 0 0 1 1 1 0 AAA domain HOOK PF05622.12 GAM23709.1 - 0.44 8.6 10.9 0.58 8.2 10.9 1.1 1 0 0 1 1 1 0 HOOK protein PRKG1_interact PF15898.5 GAM23709.1 - 0.59 11.1 7.0 20 6.1 3.3 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain YlqD PF11068.8 GAM23709.1 - 0.96 9.8 8.2 3.3 8.1 8.2 1.9 1 1 0 1 1 1 0 YlqD protein ZapB PF06005.12 GAM23709.1 - 1.2 9.7 14.5 97 3.5 14.5 2.5 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 GAM23709.1 - 1.4 9.0 9.0 0.71 10.0 1.6 2.7 2 1 1 3 3 3 0 Basic region leucine zipper YabA PF06156.13 GAM23709.1 - 2.5 8.8 11.2 8.1 7.2 5.2 2.3 1 1 1 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 GAM23709.1 - 5 7.2 10.7 10 6.1 10.7 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NRBF2 PF08961.10 GAM23709.1 - 9.1 5.8 10.0 9.7 5.7 3.2 2.2 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator FNIP PF05725.12 GAM23710.1 - 1.3e-71 236.5 35.2 3.5e-10 39.9 0.1 10.9 4 2 8 13 13 13 13 FNIP Repeat Macoilin PF09726.9 GAM23710.1 - 0.0039 15.8 6.7 0.0049 15.5 6.7 1.1 1 0 0 1 1 1 1 Macoilin family Rootletin PF15035.6 GAM23710.1 - 0.0064 16.5 8.7 0.0093 16.0 8.7 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DHR10 PF18595.1 GAM23710.1 - 0.057 13.5 10.9 0.1 12.7 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain PikAIV_N PF18605.1 GAM23710.1 - 0.12 12.0 6.4 2.1 8.0 0.2 2.5 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain bZIP_2 PF07716.15 GAM23710.1 - 0.13 12.4 8.0 1.7 8.8 1.7 2.6 1 1 1 2 2 2 0 Basic region leucine zipper DUF5082 PF16888.5 GAM23710.1 - 0.2 11.9 8.7 3.4 8.0 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DivIC PF04977.15 GAM23710.1 - 0.53 10.1 8.3 2.2 8.1 0.4 2.5 1 1 1 2 2 2 0 Septum formation initiator UPF0242 PF06785.11 GAM23710.1 - 0.95 9.5 11.1 1.8 8.6 11.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAUS-augmin3 PF14932.6 GAM23710.1 - 1.2 8.7 11.8 1.7 8.1 11.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Cnn_1N PF07989.11 GAM23710.1 - 1.3 9.2 12.5 2.5 8.3 12.5 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 GAM23710.1 - 1.6 9.2 12.1 2.6 8.6 12.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 GAM23710.1 - 1.9 9.0 14.9 20 5.7 14.9 2.3 1 1 0 1 1 1 0 Cell division protein ZapB NRBF2 PF08961.10 GAM23710.1 - 2.2 7.8 12.8 3.5 7.2 2.6 2.2 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 GAM23710.1 - 5 7.8 11.3 39 5.0 11.2 2.2 1 1 0 1 1 1 0 Initiation control protein YabA FNIP PF05725.12 GAM23711.1 - 1.6e-68 226.6 37.5 6e-11 42.3 0.2 12.7 10 4 2 13 13 13 9 FNIP Repeat MAD PF05557.13 GAM23711.1 - 0.0018 16.7 2.0 0.0018 16.7 2.0 1.5 2 0 0 2 2 2 1 Mitotic checkpoint protein Leu_zip PF15294.6 GAM23711.1 - 0.013 15.0 4.4 0.024 14.1 4.4 1.3 1 0 0 1 1 1 0 Leucine zipper Macoilin PF09726.9 GAM23711.1 - 0.016 13.8 1.8 0.022 13.4 1.8 1.1 1 0 0 1 1 1 0 Macoilin family MIF4G_like_2 PF09090.11 GAM23711.1 - 0.028 13.9 0.7 0.057 12.9 0.7 1.4 1 0 0 1 1 1 0 MIF4G like Tho2 PF11262.8 GAM23711.1 - 0.03 13.5 3.8 0.053 12.7 3.8 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 UPF0242 PF06785.11 GAM23711.1 - 0.045 13.9 3.0 0.098 12.8 3.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 GAM23711.1 - 0.083 12.2 4.3 0.12 11.7 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VGPC1_C PF16799.5 GAM23711.1 - 0.094 12.7 8.0 0.16 12.0 5.6 2.2 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 NRBF2 PF08961.10 GAM23711.1 - 0.1 12.2 10.6 0.29 10.7 0.8 2.2 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Jnk-SapK_ap_N PF09744.9 GAM23711.1 - 0.14 12.4 8.8 0.29 11.3 8.8 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF2959 PF11172.8 GAM23711.1 - 0.17 12.0 3.6 0.58 10.3 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) bZIP_2 PF07716.15 GAM23711.1 - 0.18 11.9 9.8 0.29 11.3 0.4 2.8 3 0 0 3 3 2 0 Basic region leucine zipper PRKG1_interact PF15898.5 GAM23711.1 - 0.2 12.5 5.2 4.5 8.2 1.6 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain SHE3 PF17078.5 GAM23711.1 - 0.26 11.0 8.3 0.43 10.3 8.3 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF5082 PF16888.5 GAM23711.1 - 0.27 11.5 6.6 3.1 8.1 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) YlqD PF11068.8 GAM23711.1 - 0.47 10.8 5.5 1.4 9.3 5.5 1.8 1 0 0 1 1 1 0 YlqD protein HAUS-augmin3 PF14932.6 GAM23711.1 - 0.52 9.8 5.2 0.86 9.1 5.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TMCO5 PF14992.6 GAM23711.1 - 0.53 9.8 8.1 0.84 9.2 8.1 1.2 1 0 0 1 1 1 0 TMCO5 family Peptidase_U57 PF05582.12 GAM23711.1 - 0.64 9.2 2.2 0.97 8.6 2.2 1.1 1 0 0 1 1 1 0 YabG peptidase U57 PikAIV_N PF18605.1 GAM23711.1 - 0.72 9.5 9.4 2.1 8.0 1.0 2.4 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain ZapB PF06005.12 GAM23711.1 - 0.91 10.0 15.9 79 3.8 15.9 2.4 1 1 0 1 1 1 0 Cell division protein ZapB Med30 PF11315.8 GAM23711.1 - 0.91 9.7 5.9 1.7 8.9 5.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 30 DivIC PF04977.15 GAM23711.1 - 1.1 9.1 11.9 1.1 9.1 0.6 2.6 2 1 0 2 2 2 0 Septum formation initiator Atg14 PF10186.9 GAM23711.1 - 1.4 7.9 6.0 2.5 7.1 6.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KLRAQ PF10205.9 GAM23711.1 - 1.9 8.8 8.3 1.4 9.2 5.8 1.9 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Seadorna_VP6 PF07407.11 GAM23711.1 - 2.1 7.2 3.6 4.1 6.2 3.0 1.6 1 1 1 2 2 2 0 Seadornavirus VP6 protein FlaC_arch PF05377.11 GAM23711.1 - 2.2 8.7 4.9 22 5.5 0.2 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 GAM23711.1 - 5.7 7.0 12.6 9.1 6.3 4.8 2.3 2 0 0 2 2 2 0 Prefoldin subunit YabA PF06156.13 GAM23711.1 - 8.5 7.1 11.4 1.3e+02 3.2 11.4 2.3 1 1 0 1 1 1 0 Initiation control protein YabA FNIP PF05725.12 GAM23712.1 - 1.4e-74 246.0 34.6 1.5e-09 37.9 0.0 11.4 9 1 3 12 12 11 11 FNIP Repeat BLOC1_2 PF10046.9 GAM23712.1 - 0.0018 18.6 2.6 0.0033 17.7 2.6 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 SKA2 PF16740.5 GAM23712.1 - 0.0028 17.4 0.2 0.0057 16.4 0.2 1.4 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 YlqD PF11068.8 GAM23712.1 - 0.0035 17.7 2.2 0.0071 16.7 2.2 1.4 1 0 0 1 1 1 1 YlqD protein Spc7 PF08317.11 GAM23712.1 - 0.008 15.1 1.0 0.013 14.4 1.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein bZIP_2 PF07716.15 GAM23712.1 - 0.0082 16.2 1.8 0.0082 16.2 1.8 2.0 2 0 0 2 2 1 1 Basic region leucine zipper CLZ PF16526.5 GAM23712.1 - 0.0086 16.4 1.3 0.023 15.0 1.3 1.7 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4795 PF16043.5 GAM23712.1 - 0.013 15.1 0.9 0.023 14.3 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) AAA_23 PF13476.6 GAM23712.1 - 0.022 15.3 3.0 0.03 14.8 3.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1690 PF07956.11 GAM23712.1 - 0.055 13.9 3.1 0.098 13.1 3.1 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) TPR_MLP1_2 PF07926.12 GAM23712.1 - 0.063 13.3 3.9 0.1 12.6 3.9 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 GAM23712.1 - 0.068 13.4 2.9 0.13 12.5 2.9 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LRR_5 PF13306.6 GAM23712.1 - 0.07 13.1 0.1 0.97 9.4 0.1 2.7 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) DUF16 PF01519.16 GAM23712.1 - 0.079 13.4 3.2 0.17 12.4 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 SEP PF08059.13 GAM23712.1 - 0.12 13.0 0.0 16 6.1 0.0 4.0 4 0 0 4 4 4 0 SEP domain ZapD PF07072.11 GAM23712.1 - 0.13 12.0 0.7 0.24 11.1 0.7 1.3 1 0 0 1 1 1 0 Cell division protein CortBP2 PF09727.9 GAM23712.1 - 0.14 12.1 5.7 0.22 11.4 5.7 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 Ran-binding PF05508.11 GAM23712.1 - 0.15 11.0 5.2 0.32 9.9 5.2 1.5 1 1 0 1 1 1 0 RanGTP-binding protein DUF3450 PF11932.8 GAM23712.1 - 0.16 11.3 2.5 0.27 10.5 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 GAM23712.1 - 0.18 12.1 0.3 0.34 11.2 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 GAM23712.1 - 0.19 11.8 3.0 0.33 11.0 3.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med21 PF11221.8 GAM23712.1 - 0.26 11.5 5.6 3.1 8.0 4.0 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex ABC_tran_CTD PF16326.5 GAM23712.1 - 0.28 11.5 2.1 0.56 10.5 2.1 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 GAM23712.1 - 0.52 10.8 4.0 1.5 9.3 4.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 GAM23712.1 - 0.54 10.1 2.0 1.2 8.9 2.0 1.6 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 GAM23712.1 - 0.55 10.7 8.2 1.1 9.7 8.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB FNIP PF05725.12 GAM23713.1 - 3.6e-73 241.5 17.4 2.2e-10 40.5 0.0 10.9 8 2 3 11 11 11 11 FNIP Repeat Leu_zip PF15294.6 GAM23713.1 - 0.00011 21.8 9.2 0.00017 21.2 9.2 1.1 1 0 0 1 1 1 1 Leucine zipper Tho2 PF11262.8 GAM23713.1 - 0.00061 19.1 6.0 0.001 18.3 6.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 FPP PF05911.11 GAM23713.1 - 0.001 17.4 7.6 0.0013 17.0 7.6 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Rootletin PF15035.6 GAM23713.1 - 0.0013 18.8 9.0 0.0022 18.0 9.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion OmpH PF03938.14 GAM23713.1 - 0.0029 18.0 6.1 0.0045 17.3 6.1 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) APG6_N PF17675.1 GAM23713.1 - 0.017 15.6 11.3 0.029 14.9 11.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region STAT_alpha PF01017.20 GAM23713.1 - 0.021 14.7 8.4 0.038 13.9 8.4 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain FlxA PF14282.6 GAM23713.1 - 0.032 14.2 10.0 0.066 13.2 10.0 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF4407 PF14362.6 GAM23713.1 - 0.045 13.1 2.3 0.069 12.5 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) End3 PF12761.7 GAM23713.1 - 0.057 13.6 8.3 0.11 12.6 8.3 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Cep57_MT_bd PF06657.13 GAM23713.1 - 0.088 13.3 5.6 0.2 12.1 5.6 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 YlqD PF11068.8 GAM23713.1 - 0.11 12.9 7.6 0.21 12.0 7.6 1.4 1 0 0 1 1 1 0 YlqD protein ADIP PF11559.8 GAM23713.1 - 0.13 12.4 12.9 0.28 11.2 12.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HAUS-augmin3 PF14932.6 GAM23713.1 - 0.14 11.7 10.7 0.22 11.1 10.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Cluap1 PF10234.9 GAM23713.1 - 0.16 11.3 8.4 0.24 10.8 8.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 bZIP_2 PF07716.15 GAM23713.1 - 0.18 11.9 12.8 1.7 8.8 1.6 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 GAM23713.1 - 0.18 11.6 14.6 2.5 7.9 2.6 2.4 1 1 1 2 2 2 0 Septum formation initiator FapA PF03961.13 GAM23713.1 - 0.2 10.3 9.1 0.29 9.7 9.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2203 PF09969.9 GAM23713.1 - 0.21 12.3 3.4 0.37 11.5 3.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HALZ PF02183.18 GAM23713.1 - 0.28 11.4 8.7 3.5 7.9 2.4 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper CtIP_N PF10482.9 GAM23713.1 - 0.45 10.6 10.0 2.1 8.4 0.5 2.4 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain TMPIT PF07851.13 GAM23713.1 - 0.5 9.6 5.6 0.78 8.9 5.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 GAM23713.1 - 0.63 10.7 7.9 1.4 9.6 7.9 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Fungal_TACC PF12709.7 GAM23713.1 - 0.7 10.4 10.7 3.4 8.2 10.4 2.2 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Uso1_p115_C PF04871.13 GAM23713.1 - 0.71 10.3 11.5 1.2 9.6 11.5 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.12 GAM23713.1 - 0.71 10.3 19.8 0.5 10.8 6.4 2.4 1 1 1 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 GAM23713.1 - 0.95 9.6 12.0 2.3 8.4 5.5 2.5 1 1 1 2 2 2 0 bZIP transcription factor DUF4140 PF13600.6 GAM23713.1 - 1.6 9.2 8.9 4.4 7.8 5.0 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA_23 PF13476.6 GAM23713.1 - 1.6 9.2 13.0 2.5 8.5 13.0 1.3 1 0 0 1 1 1 0 AAA domain GIT_CC PF16559.5 GAM23713.1 - 4 7.4 9.3 3.3 7.7 3.7 2.4 1 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fzo_mitofusin PF04799.13 GAM23713.1 - 4.1 6.9 9.8 2.3 7.7 6.0 2.0 1 1 1 2 2 2 0 fzo-like conserved region Cep57_CLD_2 PF14197.6 GAM23713.1 - 4.3 7.5 14.9 1.5e+02 2.6 14.6 2.4 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 FlaC_arch PF05377.11 GAM23713.1 - 5.1 7.6 10.4 15 6.1 5.7 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 GAM23713.1 - 6.6 6.9 14.6 23 5.2 14.6 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 GAM23713.1 - 7.6 6.6 16.3 20 5.2 16.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 GAM23713.1 - 8.7 6.2 14.5 37 4.2 14.5 1.8 1 1 0 1 1 1 0 Axonemal dynein light chain AAA PF00004.29 GAM23714.1 - 2.8e-91 302.8 0.0 2.8e-44 150.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM23714.1 - 1.2e-27 95.4 1.9 1.1e-15 57.1 0.8 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 GAM23714.1 - 7.6e-15 55.0 0.0 1.1e-06 28.5 0.0 3.1 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAM23714.1 - 5.5e-10 39.9 0.2 0.00015 22.2 0.1 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 GAM23714.1 - 7.7e-10 38.9 0.1 5e-05 23.3 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GAM23714.1 - 3.2e-08 33.2 0.0 0.00033 20.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_2 PF07724.14 GAM23714.1 - 3.3e-07 30.6 0.0 0.013 15.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAM23714.1 - 4.5e-07 30.2 0.5 0.16 12.2 0.1 4.3 2 2 1 4 4 4 1 AAA domain RNA_helicase PF00910.22 GAM23714.1 - 1.6e-06 28.4 0.0 0.027 14.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 GAM23714.1 - 3e-06 27.3 0.0 0.011 15.7 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_14 PF13173.6 GAM23714.1 - 4.9e-06 26.6 0.0 0.0033 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAM23714.1 - 4.9e-06 26.7 0.0 0.041 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GAM23714.1 - 5.9e-06 25.8 0.2 0.059 12.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAM23714.1 - 1.8e-05 25.3 0.0 0.028 15.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 GAM23714.1 - 0.00011 21.9 0.0 0.46 10.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 GAM23714.1 - 0.00013 21.4 0.2 0.26 10.6 0.0 2.7 3 0 0 3 3 2 2 KaiC AAA_7 PF12775.7 GAM23714.1 - 0.00017 21.2 0.0 0.14 11.7 0.0 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 GAM23714.1 - 0.00017 21.2 0.5 1.9 8.1 0.0 3.6 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 GAM23714.1 - 0.00025 21.6 0.0 0.019 15.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_3 PF07726.11 GAM23714.1 - 0.00044 20.1 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 GAM23714.1 - 0.0011 19.0 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GAM23714.1 - 0.0015 18.3 0.0 0.25 11.0 0.0 3.2 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 GAM23714.1 - 0.0017 18.1 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 GAM23714.1 - 0.0037 17.4 0.0 5.4 7.1 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 GAM23714.1 - 0.0054 17.0 0.0 3.9 7.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAM23714.1 - 0.0081 16.1 1.8 2 8.3 0.0 4.3 4 1 1 5 5 5 1 NACHT domain DUF815 PF05673.13 GAM23714.1 - 0.0087 15.2 0.0 2.2 7.4 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 GAM23714.1 - 0.013 15.3 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 GAM23714.1 - 0.017 15.1 0.0 2.1 8.4 0.0 2.9 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain Zeta_toxin PF06414.12 GAM23714.1 - 0.02 14.2 0.1 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 GAM23714.1 - 0.021 14.7 0.1 1.6 8.6 0.0 3.0 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 GAM23714.1 - 0.042 12.9 0.0 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 GAM23714.1 - 0.071 12.6 0.1 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_17 PF13207.6 GAM23714.1 - 0.11 13.0 0.1 12 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAM23714.1 - 0.11 12.2 0.0 0.93 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf-CCHC PF00098.23 GAM23715.1 - 6.7e-08 32.3 2.0 1.1e-07 31.6 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle RRM_1 PF00076.22 GAM23715.1 - 9.4e-08 31.8 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.6 GAM23715.1 - 0.00097 18.8 2.8 0.013 15.2 0.6 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 GAM23715.1 - 0.061 13.2 0.6 0.1 12.5 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Astro_capsid_p PF12226.8 GAM23715.1 - 4.6 6.3 6.9 7.9 5.5 6.9 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Ribosomal_S10 PF00338.22 GAM23716.1 - 1.4e-24 86.1 0.2 1.7e-24 85.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DCP2 PF05026.13 GAM23717.1 - 7.5e-31 106.3 2.8 7.5e-31 106.3 2.8 3.3 4 0 0 4 4 4 1 Dcp2, box A domain NUDIX PF00293.28 GAM23717.1 - 4.3e-13 49.4 0.0 8.3e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Spt20 PF12090.8 GAM23717.1 - 0.00018 21.2 13.2 0.00018 21.2 13.2 3.1 3 1 1 4 4 4 1 Spt20 family EPL1 PF10513.9 GAM23717.1 - 0.17 12.3 16.7 0.032 14.6 1.1 3.0 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF3365 PF11845.8 GAM23717.1 - 0.56 10.5 5.6 2.4 8.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) V_ATPase_I PF01496.19 GAM23717.1 - 0.82 7.5 14.6 0.015 13.3 2.6 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family YfhO PF09586.10 GAM23717.1 - 3.4 5.8 6.9 6.1 4.9 6.9 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO EMC3_TMCO1 PF01956.16 GAM23717.1 - 6.9 6.4 11.8 6.5 6.5 1.5 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Pkinase_Tyr PF07714.17 GAM23718.1 - 4.7e-59 199.8 0.0 7.1e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM23718.1 - 4.9e-51 173.6 0.0 7.7e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAM23718.1 - 1.7e-06 27.1 0.0 2.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Cbl_N2 PF02761.14 GAM23718.1 - 1.7e-05 25.5 0.1 5.3e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain SH2 PF00017.24 GAM23718.1 - 0.00031 20.8 0.0 0.00083 19.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 GAM23718.1 - 0.03 14.2 0.0 0.078 12.9 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family MRG PF05712.13 GAM23719.1 - 4.4e-41 140.4 2.9 4.4e-41 140.4 2.9 2.2 2 1 0 2 2 2 1 MRG Tudor-knot PF11717.8 GAM23719.1 - 2.1e-08 33.9 3.7 5.3e-08 32.6 3.7 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GAM23719.1 - 0.0043 16.9 2.2 0.011 15.6 1.7 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Ndc1_Nup PF09531.10 GAM23719.1 - 0.052 12.2 3.0 0.053 12.2 3.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 GAM23719.1 - 0.1 11.5 12.8 0.019 13.9 9.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) PWWP PF00855.17 GAM23719.1 - 0.11 12.9 2.1 0.3 11.5 2.1 1.8 1 0 0 1 1 1 0 PWWP domain Dicty_REP PF05086.12 GAM23719.1 - 0.11 10.4 6.7 0.15 10.0 6.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 GAM23719.1 - 0.11 12.4 3.1 0.21 11.6 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Inj_translocase PF16928.5 GAM23719.1 - 0.16 11.4 5.1 12 5.3 3.5 2.3 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome MarC PF01914.17 GAM23719.1 - 0.3 10.5 0.3 0.47 9.8 0.3 1.2 1 0 0 1 1 1 0 MarC family integral membrane protein DDHD PF02862.17 GAM23719.1 - 0.5 10.5 7.5 0.78 9.9 7.5 1.3 1 0 0 1 1 1 0 DDHD domain SSP160 PF06933.11 GAM23719.1 - 0.79 7.8 3.8 0.98 7.5 3.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Endostatin PF06482.11 GAM23719.1 - 1.2 8.6 9.6 1.9 7.9 9.6 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Neur_chan_memb PF02932.16 GAM23719.1 - 1.3 9.0 5.2 1.9 8.5 5.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 GAM23719.1 - 1.7 7.4 7.9 2 7.1 7.9 1.2 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 GAM23719.1 - 2.2 7.0 8.4 2.7 6.7 8.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Mucin PF01456.17 GAM23719.1 - 3.2 7.7 12.2 5 7.1 12.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Androgen_recep PF02166.16 GAM23719.1 - 6.1 5.6 8.9 0.19 10.5 2.7 1.5 2 0 0 2 2 2 0 Androgen receptor Ist1 PF03398.14 GAM23720.1 - 5.8e-52 175.9 3.1 7.8e-52 175.5 3.1 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Cyt-b5 PF00173.28 GAM23721.1 - 2.1e-14 53.4 0.0 4.9e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 GAM23721.1 - 6.7e-13 49.1 40.5 2e-12 47.5 16.3 3.5 2 2 0 2 2 2 1 Fatty acid desaturase Abhydrolase_1 PF00561.20 GAM23722.1 - 5.3e-10 39.4 0.6 8.6e-09 35.4 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM23722.1 - 0.00024 21.8 0.0 0.00035 21.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Spt20 PF12090.8 GAM23722.1 - 0.036 13.7 15.0 2.6 7.6 12.8 2.2 2 0 0 2 2 2 0 Spt20 family Hydrolase_4 PF12146.8 GAM23722.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Presenilin PF01080.17 GAM23722.1 - 9.1 4.9 6.1 13 4.5 6.1 1.1 1 0 0 1 1 1 0 Presenilin TPR_1 PF00515.28 GAM23723.1 - 3e-11 42.6 5.1 5.4e-05 22.8 0.6 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM23723.1 - 6.3e-10 38.4 6.8 3.6e-05 23.6 0.6 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM23723.1 - 2.5e-09 36.6 8.5 2.1e-06 27.3 3.4 2.5 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 GAM23723.1 - 4.2e-09 36.9 0.3 6.7e-09 36.3 0.3 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM23723.1 - 1.7e-08 34.0 2.1 0.0043 17.2 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM23723.1 - 1.3e-06 28.5 1.9 0.017 15.4 0.3 2.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM23723.1 - 2.9e-06 27.6 0.6 0.0043 17.7 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM23723.1 - 3.2e-06 26.8 1.2 0.045 13.8 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM23723.1 - 0.0005 20.2 0.1 0.0011 19.0 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM23723.1 - 0.0023 18.4 1.8 0.0053 17.2 1.6 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM23723.1 - 0.011 15.6 3.5 0.62 10.0 0.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HCNGP PF07818.13 GAM23723.1 - 0.045 14.4 0.0 0.045 14.4 0.0 2.1 2 0 0 2 2 2 0 HCNGP-like protein MIT PF04212.18 GAM23723.1 - 0.058 13.5 0.8 0.058 13.5 0.8 2.8 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 GAM23723.1 - 0.068 13.8 1.0 6 7.7 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5113 PF17140.4 GAM23723.1 - 1.5 8.6 5.6 5.2 6.8 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5113) TPR_17 PF13431.6 GAM23723.1 - 5.3 7.6 6.8 4.6 7.9 1.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat GAS PF13851.6 GAM23724.1 - 0.00025 20.4 14.5 0.00043 19.7 14.5 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Sec34 PF04136.15 GAM23724.1 - 0.00027 20.9 6.6 0.00027 20.9 6.6 1.6 1 1 1 2 2 2 1 Sec34-like family Fib_alpha PF08702.10 GAM23724.1 - 0.00027 21.1 7.2 0.00052 20.2 7.2 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family CENP-Q PF13094.6 GAM23724.1 - 0.0012 19.1 2.0 0.0016 18.6 2.0 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.12 GAM23724.1 - 0.0036 17.3 3.0 0.0062 16.6 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Atg14 PF10186.9 GAM23724.1 - 0.0052 15.9 3.1 0.007 15.5 3.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 GAM23724.1 - 0.0061 14.6 4.6 0.0072 14.3 4.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Yuri_gagarin PF15934.5 GAM23724.1 - 0.016 15.1 6.9 0.023 14.6 6.9 1.2 1 0 0 1 1 1 0 Yuri gagarin Spc29 PF17082.5 GAM23724.1 - 0.019 14.8 9.8 0.016 15.1 7.8 1.8 2 1 0 2 2 2 0 Spindle Pole Component 29 Mod_r PF07200.13 GAM23724.1 - 0.022 14.9 11.1 0.038 14.1 11.1 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF3450 PF11932.8 GAM23724.1 - 0.071 12.4 8.3 0.13 11.5 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SlyX PF04102.12 GAM23724.1 - 0.079 13.6 4.1 4.6 7.9 0.2 2.4 1 1 1 2 2 2 0 SlyX TMF_TATA_bd PF12325.8 GAM23724.1 - 0.11 12.7 9.3 0.16 12.2 8.5 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding JIP_LZII PF16471.5 GAM23724.1 - 0.12 12.6 5.7 0.24 11.6 5.5 1.7 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II FapA PF03961.13 GAM23724.1 - 0.12 11.0 5.1 0.14 10.7 5.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPR_MLP1_2 PF07926.12 GAM23724.1 - 0.14 12.3 13.6 0.72 9.9 13.2 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 GAM23724.1 - 0.15 12.1 3.9 0.26 11.3 3.9 1.3 1 0 0 1 1 1 0 Laminin Domain II HemX PF04375.14 GAM23724.1 - 0.17 11.2 4.0 0.24 10.7 4.0 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF5339 PF17274.2 GAM23724.1 - 0.36 11.7 8.1 0.68 10.8 7.1 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5339) CENP-H PF05837.12 GAM23724.1 - 0.46 10.9 5.8 0.77 10.2 5.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMPIT PF07851.13 GAM23724.1 - 0.52 9.5 9.5 0.75 9.0 9.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein ZapB PF06005.12 GAM23724.1 - 1.1 9.7 10.3 2.6 8.5 10.3 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DUF4407 PF14362.6 GAM23724.1 - 1.7 7.9 4.3 2.2 7.6 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cep57_CLD_2 PF14197.6 GAM23724.1 - 2.8 8.1 8.9 10 6.3 8.9 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 ACCA PF03255.14 GAM23724.1 - 7.7 6.4 8.7 1.3 8.9 5.1 1.5 2 0 0 2 2 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DivIC PF04977.15 GAM23724.1 - 9.9 6.0 10.5 0.88 9.4 2.4 2.4 1 1 1 2 2 2 0 Septum formation initiator Rad9 PF04139.13 GAM23725.1 - 9e-53 179.3 5.0 1.2e-52 178.8 5.0 1.2 1 0 0 1 1 1 1 Rad9 PCNA_N PF00705.18 GAM23725.1 - 0.0078 15.9 1.7 0.016 14.9 0.8 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain DPM2 PF07297.12 GAM23727.1 - 1.1e-17 64.1 0.1 1.2e-17 64.0 0.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) LapA_dom PF06305.11 GAM23727.1 - 0.029 14.2 0.2 0.029 14.2 0.2 1.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Ribosomal_L15e PF00827.17 GAM23728.1 - 7.4e-91 303.1 4.6 9.2e-91 302.8 4.6 1.1 1 0 0 1 1 1 1 Ribosomal L15 DUF4438 PF14505.6 GAM23729.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) Phospholip_B PF04916.13 GAM23730.1 - 1.7e-153 512.1 12.4 2e-153 511.8 12.4 1.0 1 0 0 1 1 1 1 Phospholipase B E2F_TDP PF02319.20 GAM23731.1 - 1.4e-26 92.4 0.8 1.9e-14 53.4 0.1 2.8 1 1 1 2 2 2 2 E2F/DP family winged-helix DNA-binding domain NOA36 PF06524.12 GAM23731.1 - 0.38 10.0 11.8 0.78 9.0 11.8 1.5 1 0 0 1 1 1 0 NOA36 protein 4HBT PF03061.22 GAM23732.1 - 0.0042 17.4 0.0 0.021 15.2 0.0 1.9 1 1 0 1 1 1 1 Thioesterase superfamily tRNA_int_endo PF01974.17 GAM23733.1 - 2.8e-19 69.0 0.0 5.8e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain CDRT4 PF15213.6 GAM23733.1 - 0.14 12.8 1.0 0.3 11.7 1.0 1.6 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Spt20 PF12090.8 GAM23733.1 - 1.7 8.2 17.8 0.015 14.9 8.0 2.3 3 0 0 3 3 3 0 Spt20 family HTH_3 PF01381.22 GAM23734.1 - 3.6e-15 55.7 0.1 5.8e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 GAM23734.1 - 4.7e-06 26.9 0.0 1.5e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 GAM23734.1 - 1.2e-05 25.3 0.2 4e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 GAM23734.1 - 0.00081 19.3 0.1 0.001 19.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 GAM23734.1 - 0.0012 18.9 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA MBF1 PF08523.10 GAM23734.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Multiprotein bridging factor 1 B_lectin PF01453.24 GAM23736.1 - 8.4e-17 61.6 0.6 4.1e-05 24.1 0.0 4.2 2 2 1 4 4 4 3 D-mannose binding lectin AbrB-like PF14250.6 GAM23736.1 - 0.00015 21.8 3.2 8.3 6.6 0.0 4.8 3 2 2 5 5 5 3 AbrB-like transcriptional regulator BofC_C PF08955.10 GAM23736.1 - 0.0011 19.0 0.0 4.6 7.4 0.0 3.3 3 0 0 3 3 3 2 BofC C-terminal domain zf-CHY PF05495.12 GAM23737.1 - 4.7e-14 52.6 14.3 6.9e-14 52.1 14.3 1.3 1 0 0 1 1 1 1 CHY zinc finger Zn_ribbon_SprT PF17283.2 GAM23737.1 - 0.0035 17.2 0.5 0.0035 17.2 0.5 2.6 3 0 0 3 3 3 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 GAM23737.1 - 0.0093 16.1 2.8 0.0093 16.1 2.8 2.6 2 1 0 2 2 2 1 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 GAM23737.1 - 0.0099 15.8 10.8 0.14 12.1 6.2 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 GAM23737.1 - 0.01 16.0 1.4 0.01 16.0 1.4 2.1 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf_UBZ PF18439.1 GAM23737.1 - 0.04 13.5 7.5 2.3 7.9 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 GAM23737.1 - 0.089 12.5 0.2 0.089 12.5 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 GAM23737.1 - 0.097 12.7 6.7 0.85 9.7 0.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 GAM23737.1 - 0.13 12.2 9.4 0.53 10.2 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 GAM23737.1 - 0.14 11.6 0.3 0.14 11.6 0.3 4.3 5 0 0 5 5 5 0 zinc-ribbon domain Elf1 PF05129.13 GAM23737.1 - 0.15 12.2 10.3 0.23 11.6 10.3 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_9 PF14369.6 GAM23737.1 - 0.45 10.8 0.1 0.45 10.8 0.1 3.3 3 1 0 3 3 3 0 zinc-ribbon UPF0547 PF10571.9 GAM23737.1 - 0.52 10.5 0.2 0.52 10.5 0.2 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DZR PF12773.7 GAM23737.1 - 0.6 10.2 13.3 14 5.8 13.3 2.8 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 GAM23737.1 - 2.4 8.2 12.7 0.3 11.1 2.9 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS91 PF14319.6 GAM23737.1 - 3.2 7.9 16.0 0.89 9.6 8.7 2.6 1 1 1 2 2 2 0 Transposase zinc-binding domain zinc_ribbon_10 PF10058.9 GAM23737.1 - 5.3 6.8 10.9 0.17 11.7 1.4 2.4 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein ABC_tran PF00005.27 GAM23738.1 - 1e-32 113.5 0.0 2.6e-32 112.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAM23738.1 - 2e-32 112.9 17.0 2.7e-32 112.5 17.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GAM23738.1 - 4.9e-07 29.4 0.6 5.7e-05 22.7 0.0 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DEAD PF00270.29 GAM23738.1 - 0.0018 18.1 0.0 0.0047 16.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_23 PF13476.6 GAM23738.1 - 0.0046 17.5 0.6 0.0094 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAM23738.1 - 0.015 15.0 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAM23738.1 - 0.016 15.5 0.6 0.2 11.9 0.1 2.8 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAM23738.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 GAM23738.1 - 0.025 14.4 0.6 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 GAM23738.1 - 0.031 14.3 0.0 0.086 12.9 0.0 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_5 PF07728.14 GAM23738.1 - 0.032 14.2 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 GAM23738.1 - 0.043 13.9 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 GAM23738.1 - 0.062 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 GAM23738.1 - 0.21 11.1 0.0 0.54 9.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SURF6 PF04935.12 GAM23739.1 - 1.9e-27 96.4 47.1 1.9e-27 96.4 47.1 2.4 1 1 1 2 2 2 1 Surfeit locus protein 6 RNA_pol_3_Rpc31 PF11705.8 GAM23739.1 - 0.011 16.0 31.9 0.011 16.0 31.9 2.5 2 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2380 PF09533.10 GAM23739.1 - 0.14 11.8 0.2 0.28 10.8 0.2 1.5 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) TFIIA PF03153.13 GAM23739.1 - 3.2 7.7 43.8 0.058 13.4 34.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MGC-24 PF05283.11 GAM23739.1 - 5.8 7.4 19.6 17 5.8 19.6 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HECT PF00632.25 GAM23740.1 - 2.5e-42 145.4 0.0 4.7e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.19 GAM23740.1 - 2.1e-20 73.5 6.0 4.4e-16 59.6 0.4 3.7 4 0 0 4 4 4 2 Filamin/ABP280 repeat Invasin_D3 PF09134.10 GAM23740.1 - 0.0033 17.7 0.0 0.28 11.5 0.0 3.6 3 0 0 3 3 3 1 Invasin, domain 3 DUF5626 PF18540.1 GAM23740.1 - 0.025 15.1 1.1 0.025 15.1 1.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5626) zf-MYND PF01753.18 GAM23741.1 - 8.4e-10 38.6 8.3 1.4e-09 37.9 8.3 1.4 1 0 0 1 1 1 1 MYND finger Med3 PF11593.8 GAM23741.1 - 0.024 13.9 5.4 0.031 13.5 5.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-HIT PF04438.16 GAM23741.1 - 6.1 6.8 9.5 17 5.4 9.5 1.8 1 0 0 1 1 1 0 HIT zinc finger GTP_EFTU PF00009.27 GAM23742.1 - 3.8e-63 212.6 0.0 5.5e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAM23742.1 - 2.4e-29 101.6 0.0 4.5e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 GAM23742.1 - 2.5e-20 72.3 0.0 9.4e-20 70.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAM23742.1 - 8.4e-16 58.1 0.1 2.6e-15 56.6 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAM23742.1 - 9e-14 51.3 0.1 3.5e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAM23742.1 - 0.0042 17.1 0.0 0.0095 16.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAD_M PF08527.10 GAM23742.1 - 0.006 16.3 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain zf-C3Hc3H PF13891.6 GAM23743.1 - 7e-17 61.6 4.3 1.3e-16 60.7 4.3 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain Citrate_synt PF00285.21 GAM23743.1 - 0.0028 16.8 0.1 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Citrate synthase, C-terminal domain RRXRR PF14239.6 GAM23744.1 - 0.021 14.7 0.3 0.039 13.8 0.2 1.4 1 1 0 1 1 1 0 RRXRR protein Pkinase PF00069.25 GAM23745.1 - 1.1e-71 241.3 0.0 1.7e-71 240.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM23745.1 - 2.8e-41 141.5 0.0 4.2e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM23745.1 - 0.00033 19.7 0.3 0.00056 19.0 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM23745.1 - 0.00076 18.9 0.0 0.0018 17.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM23745.1 - 0.0083 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM23745.1 - 0.016 14.0 0.1 0.058 12.2 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 GAM23745.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SgrT PF15894.5 GAM23746.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT RCC1 PF00415.18 GAM23747.1 - 1.4e-51 172.8 15.1 1.6e-11 44.6 0.4 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM23747.1 - 2.4e-31 106.8 41.0 6.7e-11 41.7 0.1 8.7 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat DUF1459 PF07312.11 GAM23747.1 - 0.49 10.7 1.8 53 4.1 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1459) Pkinase PF00069.25 GAM23749.1 - 5.3e-69 232.5 0.0 5.3e-69 232.5 0.0 3.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM23749.1 - 4.9e-31 107.9 0.0 4.9e-31 107.9 0.0 2.7 3 0 0 3 3 3 1 Protein tyrosine kinase Exonuc_VII_L PF02601.15 GAM23749.1 - 0.0042 16.7 30.6 0.011 15.3 21.5 2.3 2 0 0 2 2 2 2 Exonuclease VII, large subunit Plasmodium_Vir PF05795.11 GAM23749.1 - 0.41 10.0 0.0 0.41 10.0 0.0 3.5 2 2 1 3 3 3 0 Plasmodium vivax Vir protein Laminin_EGF PF00053.24 GAM23750.1 - 2.1 8.6 21.3 1.6 8.9 3.0 2.5 1 1 1 2 2 2 0 Laminin EGF domain ADK PF00406.22 GAM23751.1 - 3e-50 170.3 0.0 3.5e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAM23751.1 - 1.9e-35 122.3 0.0 2.3e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM23751.1 - 9.6e-10 39.1 0.0 1.3e-09 38.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAM23751.1 - 4.3e-06 27.0 0.0 1.2e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 GAM23751.1 - 0.00012 21.9 0.0 0.46 10.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.12 GAM23751.1 - 0.00092 18.5 0.1 0.0024 17.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.6 GAM23751.1 - 0.042 14.2 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAM23751.1 - 0.068 13.6 0.1 0.14 12.6 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 GAM23752.1 - 7.3e-39 133.2 0.0 1e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM23752.1 - 5.9e-07 30.0 0.3 4.6e-05 23.9 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAM23752.1 - 0.00017 21.3 0.0 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAM23752.1 - 0.00022 21.2 0.0 0.00054 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAM23752.1 - 0.0006 19.1 0.0 0.00081 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 GAM23752.1 - 0.001 19.2 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 GAM23752.1 - 0.0014 17.9 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 GAM23752.1 - 0.0017 18.6 0.2 0.065 13.5 0.1 2.2 1 1 0 2 2 2 1 AAA domain TsaE PF02367.17 GAM23752.1 - 0.002 18.1 0.1 0.0098 15.9 0.0 1.9 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 GAM23752.1 - 0.0028 17.5 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein ATPase_2 PF01637.18 GAM23752.1 - 0.0031 17.5 0.0 0.018 15.0 0.0 1.8 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 GAM23752.1 - 0.0037 17.6 0.0 0.0064 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 GAM23752.1 - 0.0044 17.1 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAM23752.1 - 0.0044 16.8 0.0 0.01 15.6 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.27 GAM23752.1 - 0.016 15.8 0.1 0.044 14.3 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 GAM23752.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 GAM23752.1 - 0.02 14.8 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 GAM23752.1 - 0.027 15.0 0.0 0.045 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAM23752.1 - 0.03 14.1 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 GAM23752.1 - 0.073 12.0 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 GAM23752.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 GAM23752.1 - 0.095 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GAM23752.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 GAM23752.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain Kinesin PF00225.23 GAM23752.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.5 1 1 0 1 1 1 0 Kinesin motor domain Sigma54_activat PF00158.26 GAM23752.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 GAM23752.1 - 0.19 11.6 0.8 0.33 10.9 0.0 1.8 3 0 0 3 3 2 0 NACHT domain Zeta_toxin PF06414.12 GAM23752.1 - 0.21 10.8 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 GAM23752.1 - 0.22 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain CoA_transf_3 PF02515.17 GAM23753.1 - 2.7e-81 273.5 0.0 4.1e-81 272.9 0.0 1.3 1 1 0 1 1 1 1 CoA-transferase family III LRR_8 PF13855.6 GAM23754.1 - 1.7e-07 30.8 10.8 1.7e-06 27.6 0.8 4.3 4 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 GAM23754.1 - 0.00015 22.0 11.8 0.034 14.6 0.1 6.9 4 2 2 7 7 7 1 Leucine Rich repeats (2 copies) RVT_1 PF00078.27 GAM23755.1 - 1.9e-37 129.0 0.0 2.7e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2-oxoacid_dh PF00198.23 GAM23756.1 - 8.3e-84 280.7 0.0 1.3e-83 280.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAM23756.1 - 5.9e-20 70.9 0.0 1.2e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAM23756.1 - 1.6e-12 47.5 0.1 3.7e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Ribosomal_60s PF00428.19 GAM23756.1 - 0.0017 18.9 9.8 0.27 11.9 2.3 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein OAD_gamma PF04277.13 GAM23756.1 - 1.8 9.2 7.5 3.9 8.1 1.1 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF3597 PF12200.8 GAM23756.1 - 4.4 7.9 7.7 17 6.0 3.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) MMR_HSR1 PF01926.23 GAM23757.1 - 7.1e-10 39.0 0.1 3.8e-09 36.6 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM23757.1 - 2.5e-06 27.5 0.1 2.5e-05 24.3 0.1 2.2 1 1 0 1 1 1 1 RsgA GTPase Roc PF08477.13 GAM23757.1 - 0.0021 18.3 0.2 1.3 9.2 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 GAM23757.1 - 0.0033 16.8 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 Septin Ras PF00071.22 GAM23757.1 - 0.012 15.2 0.1 5.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.18 GAM23757.1 - 0.013 15.0 0.3 0.14 11.7 0.0 2.4 3 0 0 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.23 GAM23757.1 - 0.014 15.5 5.1 0.2 11.7 0.2 3.0 2 1 1 3 3 3 0 Dynamin family ATPase_2 PF01637.18 GAM23757.1 - 0.036 14.0 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 GAM23757.1 - 0.043 14.3 0.3 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ESM4 PF15952.5 GAM23757.1 - 0.053 13.9 3.1 0.085 13.3 2.3 1.6 2 0 0 2 2 2 0 Enhancer of split M4 family CobU PF02283.16 GAM23757.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase UPF0172 PF03665.13 GAM23757.1 - 0.11 12.5 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Ribosomal_L28 PF00830.19 GAM23758.1 - 2.3e-17 62.9 0.0 3.8e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L28 family MIF4G PF02854.19 GAM23759.1 - 7.5e-32 110.7 17.8 1.5e-13 50.9 2.6 4.2 4 1 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 GAM23759.1 - 2.8e-11 44.3 10.5 2.8e-11 44.3 10.5 7.3 6 3 2 8 8 8 1 Up-frameshift suppressor 2 NAC PF01849.18 GAM23760.1 - 1.6e-18 66.4 0.0 2.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 NAC domain CSTF1_dimer PF16699.5 GAM23760.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain cobW PF02492.19 GAM23761.1 - 2.7e-53 180.2 0.3 3.7e-53 179.7 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAM23761.1 - 2.7e-18 65.7 0.0 4.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 GAM23761.1 - 3e-06 27.2 1.4 0.0066 16.4 0.5 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM23761.1 - 0.0073 16.4 0.1 0.025 14.6 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 GAM23761.1 - 0.016 15.7 3.7 0.66 10.4 0.5 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 GAM23761.1 - 0.016 14.3 0.1 0.039 13.0 0.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 GAM23761.1 - 0.039 13.7 1.0 0.098 12.4 0.9 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 GAM23761.1 - 0.064 13.3 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Erythro_esteras PF05139.14 GAM23761.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Erythromycin esterase Fur_reg_FbpB PF13040.6 GAM23761.1 - 0.12 11.9 0.7 0.34 10.5 0.7 1.7 1 0 0 1 1 1 0 Fur-regulated basic protein B dNK PF01712.19 GAM23761.1 - 0.15 11.9 1.7 0.98 9.2 0.1 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase ABC_tran PF00005.27 GAM23761.1 - 0.35 11.4 2.1 2.8 8.4 2.1 2.2 1 1 0 1 1 1 0 ABC transporter Yip1 PF04893.17 GAM23762.1 - 1.2e-13 51.1 10.4 1.2e-13 51.1 10.4 1.5 1 1 1 2 2 2 1 Yip1 domain YIF1 PF03878.15 GAM23762.1 - 0.037 13.6 11.8 0.26 10.8 11.8 2.0 1 1 0 1 1 1 0 YIF1 DUF2070 PF09843.9 GAM23762.1 - 3 6.0 5.9 3.9 5.6 5.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1700 PF08006.11 GAM23762.1 - 7.6 6.0 10.2 3.2 7.2 7.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) Glutaredoxin PF00462.24 GAM23764.1 - 0.00043 20.4 0.0 0.0009 19.4 0.0 1.6 1 1 0 1 1 1 1 Glutaredoxin MctB PF11382.8 GAM23764.1 - 0.063 13.0 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Rft-1 PF04506.13 GAM23765.1 - 2.1e-122 409.5 20.6 2.6e-122 409.2 20.6 1.0 1 0 0 1 1 1 1 Rft protein Viral_Beta_CD PF04530.12 GAM23765.1 - 0.049 13.9 1.9 0.07 13.4 0.2 2.2 2 0 0 2 2 2 0 Viral Beta C/D like family RasGAP PF00616.19 GAM23766.1 - 2.9e-11 43.5 0.0 0.00012 21.9 0.0 2.3 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase ROS_MUCR PF05443.11 GAM23766.1 - 0.12 12.4 0.0 0.37 10.8 0.2 1.8 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Macoilin PF09726.9 GAM23766.1 - 1.9 7.0 9.1 2.5 6.6 9.1 1.1 1 0 0 1 1 1 0 Macoilin family AIG1 PF04548.16 GAM23767.1 - 9.9e-23 80.6 0.0 2.1e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GAM23767.1 - 5.9e-10 39.2 0.0 5.9e-10 39.2 0.0 1.7 2 0 0 2 2 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM23767.1 - 1.9e-05 24.6 0.1 3.7e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 GAM23767.1 - 0.00021 21.4 4.9 0.016 15.2 0.1 3.1 2 1 1 3 3 3 2 Dynamin family Septin PF00735.18 GAM23767.1 - 0.00022 20.6 0.3 0.0008 18.8 0.3 1.9 1 1 0 1 1 1 1 Septin AAA_16 PF13191.6 GAM23767.1 - 0.00095 19.6 0.0 0.0051 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Miga PF10265.9 GAM23767.1 - 0.005 15.9 0.3 0.0068 15.4 0.3 1.1 1 0 0 1 1 1 1 Mitoguardin AAA_7 PF12775.7 GAM23767.1 - 0.0058 16.2 0.0 0.034 13.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region FeoB_N PF02421.18 GAM23767.1 - 0.014 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B T2SSE PF00437.20 GAM23767.1 - 0.018 14.1 0.1 0.031 13.3 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.13 GAM23767.1 - 0.019 14.1 0.2 0.058 12.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 GAM23767.1 - 0.021 15.3 0.1 0.092 13.3 0.1 2.0 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 GAM23767.1 - 0.047 13.0 0.3 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 GAM23767.1 - 0.054 12.8 0.1 0.092 12.1 0.1 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sigma54_activat PF00158.26 GAM23767.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 GAM23767.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TniB PF05621.11 GAM23767.1 - 0.19 11.1 0.2 1.4 8.2 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein GATA PF00320.27 GAM23768.1 - 2.5e-14 52.6 3.3 2.5e-14 52.6 3.3 1.9 2 0 0 2 2 2 1 GATA zinc finger Urocanase PF01175.18 GAM23768.1 - 0.19 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain Sad1_UNC PF07738.13 GAM23769.1 - 1.6e-30 105.8 0.6 1.6e-30 105.8 0.6 3.0 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal HHH_6 PF14579.6 GAM23769.1 - 0.079 13.2 0.9 12 6.3 0.1 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix motif MpPF26 PF07666.11 GAM23769.1 - 9.1 6.4 8.0 1.5 8.9 0.5 2.5 2 0 0 2 2 2 0 M penetrans paralogue family 26 MMM1 PF10296.9 GAM23771.1 - 2.4e-14 53.1 1.2 2.4e-14 53.1 1.2 2.3 1 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 GPHR_N PF12537.8 GAM23771.1 - 0.0066 16.5 1.2 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF2681 PF10883.8 GAM23771.1 - 0.0082 16.5 2.9 0.0082 16.5 2.9 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2681) TFIIA PF03153.13 GAM23771.1 - 0.017 15.2 30.5 0.14 12.1 17.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 GAM23771.1 - 0.026 14.3 5.0 0.24 11.1 0.3 2.2 2 0 0 2 2 2 0 Connexin DUF4834 PF16118.5 GAM23771.1 - 0.031 15.2 1.3 0.031 15.2 1.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) HemY_N PF07219.13 GAM23771.1 - 0.41 10.9 0.0 0.41 10.9 0.0 1.7 2 0 0 2 2 2 0 HemY protein N-terminus DUF2852 PF11014.8 GAM23771.1 - 0.5 10.5 0.1 0.5 10.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) EMC3_TMCO1 PF01956.16 GAM23771.1 - 2.7 7.7 8.7 1.1 9.0 1.4 3.0 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like Serinc PF03348.15 GAM23771.1 - 3.2 6.6 5.4 1.5 7.7 0.1 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) Imm9 PF15587.6 GAM23772.1 - 0.062 13.0 0.4 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 9 Dicty_CTDC PF00526.18 GAM23773.1 - 1.1e-14 54.0 42.6 2.3e-08 33.7 1.1 15.0 15 2 1 16 16 16 6 Dictyostelium (slime mold) repeat PA14 PF07691.12 GAM23773.1 - 1.7e-09 37.7 0.0 2.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF3318 PF11780.8 GAM23773.1 - 0.34 10.9 0.2 0.54 10.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Keratin_assoc PF09775.9 GAM23775.1 - 2.5e-29 101.5 5.6 3.9e-29 100.9 5.6 1.3 1 1 0 1 1 1 1 Keratinocyte-associated protein 2 Peptidase_M50B PF13398.6 GAM23775.1 - 0.23 11.1 7.7 0.07 12.8 4.7 1.6 1 1 0 1 1 1 0 Peptidase M50B-like DMT_YdcZ PF04657.13 GAM23775.1 - 0.29 11.4 7.1 0.16 12.2 1.5 2.1 1 1 1 2 2 2 0 Putative inner membrane exporter, YdcZ RseC_MucC PF04246.12 GAM23775.1 - 0.34 10.8 3.0 5.5 7.0 0.9 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ABC2_membrane_3 PF12698.7 GAM23775.1 - 0.44 9.6 11.3 0.56 9.2 11.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Flp_Fap PF04964.14 GAM23775.1 - 0.44 10.4 3.8 0.91 9.4 0.0 2.7 3 0 0 3 3 3 0 Flp/Fap pilin component DUF2892 PF11127.8 GAM23775.1 - 1.4 9.0 4.7 2.6 8.1 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2892) PRIMA1 PF16101.5 GAM23776.1 - 3.7 7.6 11.4 0.21 11.6 6.1 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 FNIP PF05725.12 GAM23777.1 - 1.1e-66 220.8 32.8 2e-11 43.9 0.1 10.4 8 3 0 10 10 10 8 FNIP Repeat F-box PF00646.33 GAM23777.1 - 0.2 11.6 4.8 0.26 11.2 0.8 2.8 3 0 0 3 3 3 0 F-box domain DUF1769 PF08588.10 GAM23777.1 - 0.87 9.8 5.6 21 5.4 0.1 5.6 8 1 1 9 9 9 0 Protein of unknown function (DUF1769) CK_II_beta PF01214.18 GAM23778.1 - 1.9e-80 269.0 0.0 2.3e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 GAM23778.1 - 0.017 15.2 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases DUF3326 PF11805.8 GAM23778.1 - 0.2 10.5 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) DUF1765 PF08578.10 GAM23779.1 - 1.6e-24 86.7 0.8 2.4e-23 82.9 0.5 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) SAT PF16073.5 GAM23779.1 - 2.2 7.9 4.7 4.2 7.0 4.7 1.4 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis SPX PF03105.19 GAM23779.1 - 9.6 6.0 27.7 0.67 9.8 4.7 2.2 2 0 0 2 2 2 0 SPX domain ACC_central PF08326.12 GAM23780.1 - 4.2e-174 580.7 6.3 5.5e-174 580.3 6.3 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 GAM23780.1 - 1.5e-160 535.1 0.0 2.4e-160 534.4 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 GAM23780.1 - 1.4e-49 168.4 0.0 2.7e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAM23780.1 - 1.5e-28 99.6 0.0 4e-28 98.2 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAM23780.1 - 7.7e-20 71.0 0.0 2.2e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAM23780.1 - 4.2e-12 45.7 0.1 9.1e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 GAM23780.1 - 0.00089 18.9 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAM23780.1 - 0.0015 18.1 0.1 0.0049 16.4 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 GAM23780.1 - 0.0032 17.5 0.0 0.009 16.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain BORCS7 PF16088.5 GAM23780.1 - 0.17 12.2 3.2 0.51 10.6 3.2 1.8 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 Herpes_UL14 PF03580.14 GAM23780.1 - 0.17 12.1 2.1 0.3 11.3 0.2 2.3 2 0 0 2 2 2 0 Herpesvirus UL14-like protein DUF4477 PF14780.6 GAM23780.1 - 0.88 9.2 2.7 3.4 7.2 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) ALG11_N PF15924.5 GAM23781.1 - 0.05 13.7 0.5 0.092 12.8 0.1 1.6 1 1 0 1 1 1 0 ALG11 mannosyltransferase N-terminus BTG PF07742.12 GAM23781.1 - 0.084 12.7 0.4 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 BTG family DUF4810 PF16068.5 GAM23781.1 - 0.45 11.1 4.4 0.64 10.6 1.3 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4810) HECT PF00632.25 GAM23782.1 - 1.1e-59 202.4 0.1 2.5e-59 201.3 0.1 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 GAM23782.1 - 2.7e-18 66.2 0.3 7.4e-18 64.8 0.3 1.9 1 0 0 1 1 1 1 SPRY domain PH PF00169.29 GAM23782.1 - 1.4e-16 60.9 0.2 5.2e-16 59.1 0.2 2.1 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 GAM23782.1 - 1.1e-09 38.7 1.3 3.5e-09 37.1 1.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain CUB PF00431.20 GAM23782.1 - 0.00011 22.5 0.0 1 9.7 0.0 4.1 4 0 0 4 4 4 2 CUB domain PH_11 PF15413.6 GAM23782.1 - 0.092 13.2 3.4 0.11 12.9 0.4 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain FNIP PF05725.12 GAM23784.1 - 0.00082 19.5 0.0 0.0035 17.5 0.0 2.1 1 1 1 2 2 2 1 FNIP Repeat FNIP PF05725.12 GAM23785.1 - 1.9e-05 24.7 0.8 0.0056 16.8 0.0 3.7 4 0 0 4 4 4 2 FNIP Repeat LRR_6 PF13516.6 GAM23788.1 - 0.0004 20.2 0.8 2.9 8.2 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeat FNIP PF05725.12 GAM23789.1 - 2.6e-13 49.9 6.9 9.3e-07 28.9 0.2 7.0 6 1 1 7 7 7 5 FNIP Repeat LRR_6 PF13516.6 GAM23790.1 - 0.32 11.2 7.7 6.6 7.1 0.3 3.5 4 0 0 4 4 4 0 Leucine Rich repeat FNIP PF05725.12 GAM23792.1 - 7.3e-15 54.9 0.6 9.5e-08 32.1 0.3 2.4 2 0 0 2 2 2 2 FNIP Repeat DUF4832 PF16116.5 GAM23792.1 - 0.14 12.0 0.1 0.33 10.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4832) FNIP PF05725.12 GAM23793.1 - 3.3e-48 161.6 13.6 2.1e-15 56.6 0.5 5.2 3 1 3 6 6 6 6 FNIP Repeat TIP41 PF04176.13 GAM23794.1 - 1.5e-59 200.3 0.1 2.1e-59 199.9 0.1 1.2 1 0 0 1 1 1 1 TIP41-like family Dicty_CTDC PF00526.18 GAM23795.1 - 3.4e-10 39.6 34.5 2.7e-05 24.0 10.4 15.9 13 3 1 14 14 14 6 Dictyostelium (slime mold) repeat PA14 PF07691.12 GAM23795.1 - 2e-06 27.7 0.0 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain SH3_19 PF18597.1 GAM23795.1 - 1.5 8.7 8.3 9.7 6.1 0.3 4.0 3 0 0 3 3 3 0 Myosin X N-terminal SH3 domain SelP_N PF04592.14 GAM23796.1 - 0.032 13.6 11.3 0.031 13.7 11.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 GAM23796.1 - 0.1 11.8 2.0 0.089 12.0 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Bmp PF02608.14 GAM23797.1 - 1.1e-18 67.3 2.0 1.4e-18 66.9 2.0 1.1 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like 7tm_3 PF00003.22 GAM23798.1 - 6.6e-41 140.6 16.7 8.6e-41 140.2 16.7 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR T4SS_CagC PF16943.5 GAM23798.1 - 0.49 10.6 4.4 0.34 11.1 1.6 2.1 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system 7tm_3 PF00003.22 GAM23799.1 - 2.1e-40 138.9 18.4 3.3e-40 138.3 18.4 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 GAM23799.1 - 1.7e-15 56.8 0.3 1.7e-15 56.8 0.3 2.4 2 1 1 3 3 3 1 ABC transporter substrate-binding protein PnrA-like DUF4271 PF14093.6 GAM23799.1 - 0.092 12.7 20.6 0.063 13.2 4.4 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4271) DMT_YdcZ PF04657.13 GAM23799.1 - 0.47 10.7 16.2 0.48 10.7 1.5 3.0 3 0 0 3 3 3 0 Putative inner membrane exporter, YdcZ MAP17 PF15807.5 GAM23799.1 - 2.8 8.2 7.4 9.5 6.5 0.3 3.3 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Suf PF05843.14 GAM23800.1 - 4.8e-85 286.1 0.1 4.8e-85 286.1 0.1 6.5 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) HAT PF02184.16 GAM23800.1 - 3.4e-07 30.1 0.3 0.022 14.7 0.0 2.8 2 0 0 2 2 2 2 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 GAM23800.1 - 6.5e-06 26.5 0.0 0.39 11.7 0.0 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM23800.1 - 4.8e-05 23.8 0.1 0.0074 16.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM23800.1 - 0.0029 17.6 0.8 0.82 9.9 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM23800.1 - 0.011 16.3 1.5 11 6.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM23800.1 - 0.018 15.2 0.1 0.29 11.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras_bdg_2 PF14847.6 GAM23800.1 - 0.036 14.4 0.5 0.22 11.9 0.1 2.5 2 0 0 2 2 2 0 Ras-binding domain of Byr2 LIM PF00412.22 GAM23801.1 - 1.5e-09 37.9 4.6 3e-09 37.0 4.6 1.5 1 0 0 1 1 1 1 LIM domain OTU PF02338.19 GAM23802.1 - 6.2e-19 68.7 0.6 1.4e-18 67.6 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 GAM23802.1 - 5e-07 29.4 2.2 0.012 15.1 0.2 2.8 1 1 0 2 2 2 2 Peptidase C65 Otubain SR-25 PF10500.9 GAM23802.1 - 0.11 12.1 11.3 0.19 11.3 11.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Patched PF02460.18 GAM23802.1 - 2.3 6.2 5.4 3.3 5.7 5.4 1.2 1 0 0 1 1 1 0 Patched family EF-hand_1 PF00036.32 GAM23803.1 - 1.4e-19 68.1 5.4 7.8e-06 25.1 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAM23803.1 - 3.3e-17 62.7 3.7 6.1e-10 39.4 0.4 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GAM23803.1 - 2e-15 55.3 3.8 1.2e-05 24.8 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 GAM23803.1 - 2.6e-09 36.8 6.1 0.00043 20.1 0.9 4.6 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GAM23803.1 - 3.9e-07 29.3 10.2 0.00012 21.4 0.1 4.5 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 GAM23803.1 - 3.6e-05 24.0 0.0 0.0018 18.6 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 GAM23803.1 - 0.00061 20.1 0.2 0.33 11.3 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region M16C_assoc PF08367.11 GAM23803.1 - 0.00068 18.9 1.0 0.0011 18.2 0.9 1.5 1 1 0 1 1 1 1 Peptidase M16C associated Dockerin_1 PF00404.18 GAM23803.1 - 0.028 14.6 0.4 0.4 10.9 0.2 2.6 1 1 2 3 3 3 0 Dockerin type I domain EF-hand_11 PF08976.11 GAM23803.1 - 0.038 14.9 0.6 6.3 7.7 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain UPF0220 PF05255.11 GAM23804.1 - 0.014 14.9 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Chromo PF00385.24 GAM23806.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DNase_II PF03265.15 GAM23807.1 - 1.1e-26 93.9 2.5 3.4e-14 52.9 2.8 2.4 2 0 0 2 2 2 2 Deoxyribonuclease II TIG PF01833.24 GAM23807.1 - 5.8e-21 74.4 12.7 7.9e-08 32.3 2.2 3.7 3 0 0 3 3 3 3 IPT/TIG domain PGM_PMM_I PF02878.16 GAM23808.1 - 1.4e-28 99.3 0.0 3.8e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 GAM23808.1 - 2.4e-22 79.5 0.0 5e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 GAM23808.1 - 3.6e-18 65.8 0.0 7.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 GAM23808.1 - 1.8e-06 28.0 0.3 4e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2179 PF10035.9 GAM23808.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF1682 PF07946.14 GAM23809.1 - 5.3e-83 278.9 3.8 8.3e-83 278.3 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Orf78 PF06024.12 GAM23809.1 - 1 9.7 3.8 1.4 9.3 0.1 2.5 2 0 0 2 2 2 0 Orf78 (ac78) CLN3 PF02487.17 GAM23809.1 - 7.5 5.5 8.3 1.8 7.5 0.2 2.3 2 0 0 2 2 2 0 CLN3 protein zf-RING_2 PF13639.6 GAM23810.1 - 8.1e-06 26.1 9.8 8.1e-06 26.1 9.8 7.0 5 2 2 7 7 7 1 Ring finger domain zf-RING_UBOX PF13445.6 GAM23810.1 - 7.1e-05 22.8 5.6 7.1e-05 22.8 5.6 6.6 7 1 0 7 7 7 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAM23810.1 - 0.0012 19.1 8.4 0.0012 19.1 8.4 6.0 3 2 1 6 6 6 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAM23810.1 - 0.0033 17.4 9.6 0.0033 17.4 9.6 7.3 6 3 0 6 6 6 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAM23810.1 - 0.0054 16.6 10.0 0.0054 16.6 10.0 7.5 6 3 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAM23810.1 - 0.0092 15.7 9.5 0.0092 15.7 9.5 4.7 5 0 0 5 5 5 1 RING-like zinc finger C2 PF00168.30 GAM23811.1 - 4.7e-18 65.4 0.1 9.5e-18 64.4 0.1 1.5 1 0 0 1 1 1 1 C2 domain zf-RING_UBOX PF13445.6 GAM23811.1 - 0.0014 18.6 3.9 0.0014 18.6 3.9 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAM23811.1 - 0.072 13.1 7.5 0.18 11.8 7.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 GAM23811.1 - 0.67 9.9 11.5 0.084 12.8 7.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L13e PF01294.18 GAM23812.1 - 4.8e-72 241.6 6.9 7.2e-72 241.0 6.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Use1 PF09753.9 GAM23812.1 - 0.12 12.0 3.8 0.2 11.4 3.8 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 D-ser_dehydrat PF14031.6 GAM23813.1 - 9.8e-19 67.8 0.1 4.2e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 GAM23813.1 - 9e-18 64.7 0.0 1.3e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain KIX_2 PF16987.5 GAM23814.1 - 0.053 13.5 0.4 0.15 12.1 0.1 1.9 2 1 1 3 3 3 0 KIX domain P_C10 PF14974.6 GAM23814.1 - 0.055 13.6 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein C10 DUF3877 PF12993.7 GAM23814.1 - 0.055 13.3 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Band_7 PF01145.25 GAM23814.1 - 0.1 12.6 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 SPFH domain / Band 7 family SAPIS-gp6 PF16722.5 GAM23815.1 - 0.015 15.7 0.6 0.06 13.8 0.6 2.1 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Ras PF00071.22 GAM23816.1 - 6.3e-50 168.9 0.0 7.5e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM23816.1 - 1e-22 80.6 0.0 1.8e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM23816.1 - 6.9e-07 28.9 0.0 9.3e-07 28.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family CEBP_ZZ PF16366.5 GAM23817.1 - 0.067 13.4 0.4 0.16 12.2 0.4 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF2619 PF10942.8 GAM23817.1 - 0.069 13.2 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2619) zf-C3HC4_2 PF13923.6 GAM23817.1 - 0.083 12.8 0.2 0.083 12.8 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Xpo1 PF08389.12 GAM23818.1 - 0.0026 17.8 0.9 0.0026 17.8 0.9 2.5 2 0 0 2 2 2 1 Exportin 1-like protein UCH PF00443.29 GAM23819.1 - 2.7e-43 148.3 7.1 2.7e-43 148.3 7.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM23819.1 - 1e-22 81.2 10.5 1e-22 81.2 10.5 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 GAM23819.1 - 0.01 15.4 10.6 0.63 9.5 0.2 4.1 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PH PF00169.29 GAM23821.1 - 4.4e-09 36.8 0.0 8.4e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 GAM23821.1 - 5.9e-05 23.3 0.0 9.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAM23821.1 - 0.00018 21.7 0.0 0.00027 21.1 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 GAM23821.1 - 0.024 14.7 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 PH domain Chorion_3 PF05387.11 GAM23821.1 - 0.035 13.7 10.5 0.046 13.4 10.5 1.2 1 0 0 1 1 1 0 Chorion family 3 PH_11 PF15413.6 GAM23821.1 - 0.063 13.7 0.2 0.11 12.9 0.2 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain CLZ PF16526.5 GAM23822.1 - 0.038 14.3 2.7 0.038 14.3 2.7 5.4 3 1 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2383 PF09537.10 GAM23822.1 - 0.04 14.3 17.5 0.18 12.2 3.9 4.4 3 2 1 4 4 4 0 Domain of unknown function (DUF2383) LST1 PF05083.13 GAM23822.1 - 0.62 10.4 3.3 0.7 10.2 1.0 2.3 2 0 0 2 2 2 0 LST-1 protein DUF1818 PF08848.11 GAM23822.1 - 6.5 6.9 10.1 0.62 10.2 3.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1818) DUF3573 PF12097.8 GAM23822.1 - 9.7 4.9 6.5 9.4 4.9 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Sulfotransfer_2 PF03567.14 GAM23823.1 - 5.2e-11 42.9 0.1 2.6e-09 37.4 0.1 2.4 1 1 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 GAM23823.1 - 2.3e-07 30.1 1.7 9.5e-06 24.7 1.7 2.6 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase ABC_membrane_3 PF13748.6 GAM23823.1 - 0.63 9.2 2.7 0.89 8.7 0.5 2.0 2 0 0 2 2 2 0 ABC transporter transmembrane region G-alpha PF00503.20 GAM23824.1 - 7.5e-107 357.5 14.5 7.5e-107 357.5 14.5 1.5 2 0 0 2 2 2 1 G-protein alpha subunit PH PF00169.29 GAM23824.1 - 4.3e-14 52.9 0.7 1.6e-13 51.1 0.5 2.1 2 0 0 2 2 2 1 PH domain Arf PF00025.21 GAM23824.1 - 4.2e-12 45.9 1.8 2.6e-08 33.5 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAM23824.1 - 0.00078 19.7 0.2 2.9 8.1 0.0 3.1 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 GAM23824.1 - 0.0051 16.2 0.1 0.015 14.8 0.1 1.8 2 0 0 2 2 2 1 Bacterial TniB protein Gtr1_RagA PF04670.12 GAM23824.1 - 0.0068 15.8 8.6 0.013 14.9 0.4 3.0 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region ProRS-C_1 PF09180.11 GAM23825.1 - 4.1e-23 81.4 0.8 4.1e-23 81.4 0.8 2.0 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 GAM23825.1 - 2.3e-18 66.8 0.0 4.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAM23825.1 - 2.2e-15 56.6 0.0 5.4e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain OPA3 PF07047.12 GAM23826.1 - 1.3e-29 102.5 0.2 1.7e-29 102.1 0.2 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Yuri_gagarin PF15934.5 GAM23826.1 - 0.00079 19.3 0.1 0.001 18.9 0.1 1.1 1 0 0 1 1 1 1 Yuri gagarin His_Phos_2 PF00328.22 GAM23826.1 - 0.012 15.0 0.2 0.014 14.8 0.2 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Allexi_40kDa PF05549.11 GAM23826.1 - 0.019 14.5 0.2 0.025 14.1 0.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF3837 PF12939.7 GAM23826.1 - 0.063 13.7 0.2 0.11 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) SlyX PF04102.12 GAM23826.1 - 0.098 13.3 0.1 0.18 12.4 0.1 1.4 1 0 0 1 1 1 0 SlyX bZIP_2 PF07716.15 GAM23826.1 - 0.2 11.8 3.9 0.35 11.0 3.9 1.4 1 0 0 1 1 1 0 Basic region leucine zipper zf-HIT PF04438.16 GAM23827.1 - 4.8e-09 35.9 10.7 8.6e-09 35.1 10.7 1.4 1 0 0 1 1 1 1 HIT zinc finger NOA36 PF06524.12 GAM23827.1 - 1.5 8.1 11.8 3.1 7.0 2.2 2.1 2 0 0 2 2 2 0 NOA36 protein AMP-binding PF00501.28 GAM23828.1 - 2.2e-25 89.1 0.0 4e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme DUF4383 PF14325.6 GAM23828.1 - 0.047 14.0 0.5 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) DEAD PF00270.29 GAM23828.1 - 0.11 12.2 0.6 0.98 9.2 0.5 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase CBS PF00571.28 GAM23828.1 - 0.14 12.6 0.8 64 4.1 0.1 3.5 3 0 0 3 3 3 0 CBS domain N2227 PF07942.12 GAM23830.1 - 4.6e-92 308.1 0.2 5.7e-92 307.8 0.2 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 GAM23830.1 - 0.00024 21.7 0.0 0.0019 18.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM23830.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAM23830.1 - 0.037 14.8 0.0 0.12 13.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAM23830.1 - 0.11 13.3 0.0 1.1 10.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain DUF5579 PF17742.1 GAM23830.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5579) Complex1_LYR_2 PF13233.6 GAM23831.1 - 3.2e-12 47.0 0.2 4.6e-12 46.5 0.2 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAM23831.1 - 1.3e-06 28.4 0.8 1.5e-06 28.1 0.1 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) ECM1 PF05782.11 GAM23833.1 - 0.084 11.8 4.1 0.12 11.2 4.1 1.3 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Septin PF00735.18 GAM23834.1 - 8.9e-06 25.2 0.1 1.8e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 GAM23834.1 - 9.5e-06 25.6 0.2 0.055 13.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM23834.1 - 0.021 14.9 0.1 0.06 13.4 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DHHW PF14286.6 GAM23834.1 - 0.077 12.3 0.3 0.14 11.4 0.3 1.3 1 0 0 1 1 1 0 DHHW protein AAA_16 PF13191.6 GAM23834.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAM23834.1 - 0.13 12.5 0.0 0.63 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAM23835.1 - 0.0055 16.8 0.0 0.015 15.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 GAM23835.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAM23835.1 - 0.023 14.6 0.0 3.8 7.4 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 GAM23835.1 - 0.045 14.0 0.0 0.27 11.5 0.0 2.3 1 1 2 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 GAM23835.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase ApoA-II PF04711.13 GAM23835.1 - 0.3 11.3 1.1 6.9 6.9 0.1 2.5 2 1 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) RsgA_GTPase PF03193.16 GAM23836.1 - 0.0021 18.0 0.0 0.58 10.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM23836.1 - 0.006 16.6 0.0 0.023 14.8 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase ubiquitin PF00240.23 GAM23836.1 - 0.032 14.0 0.8 0.074 12.8 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin family AAA_29 PF13555.6 GAM23836.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Striatin PF08232.12 GAM23837.1 - 0.074 13.6 0.2 0.14 12.7 0.2 1.4 1 0 0 1 1 1 0 Striatin family AAA_11 PF13086.6 GAM23838.1 - 1.6e-72 244.4 5.3 1.7e-35 123.1 1.6 2.9 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.6 GAM23838.1 - 2.8e-55 187.1 0.0 7.8e-55 185.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAM23838.1 - 6.5e-10 39.0 0.3 0.0013 18.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAM23838.1 - 1.4e-08 35.2 1.9 0.0034 17.7 0.1 3.1 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 GAM23838.1 - 4.6e-07 29.8 0.0 0.0044 16.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 GAM23838.1 - 0.003 16.9 0.9 0.49 9.6 0.0 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 GAM23838.1 - 0.01 15.8 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAM23838.1 - 0.012 15.9 0.4 0.13 12.6 0.1 2.9 4 1 0 4 4 4 0 AAA domain UvrD-helicase PF00580.21 GAM23838.1 - 0.014 15.0 1.0 0.44 10.0 0.0 2.8 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 GAM23838.1 - 0.019 14.4 0.1 0.74 9.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 GAM23838.1 - 0.029 14.7 0.0 0.084 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 GAM23838.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RINGv PF12906.7 GAM23839.1 - 2e-05 24.6 14.5 2e-05 24.6 14.5 3.3 2 1 0 2 2 2 1 RING-variant domain FOXO-TAD PF16676.5 GAM23840.1 - 0.1 13.0 0.3 16 6.0 0.1 2.4 2 0 0 2 2 2 0 Transactivation domain of FOXO protein family Cbl_N2 PF02761.14 GAM23841.1 - 2.1e-16 60.4 2.2 2.3e-16 60.3 0.2 2.0 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain zf-C3HC4_3 PF13920.6 GAM23841.1 - 1e-13 50.9 12.5 1.8e-13 50.1 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH2 PF00017.24 GAM23841.1 - 1.3e-07 31.6 0.0 5e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 SH2 domain Prok-RING_4 PF14447.6 GAM23841.1 - 0.0001 22.1 12.6 0.0002 21.2 12.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Cbl_N3 PF02762.14 GAM23841.1 - 0.005 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain TFIIA PF03153.13 GAM23841.1 - 0.017 15.2 8.7 0.52 10.3 0.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 GAM23841.1 - 0.065 12.8 19.6 0.78 9.3 3.9 3.1 3 0 0 3 3 3 0 Spt20 family zf-RING_5 PF14634.6 GAM23841.1 - 0.1 12.6 14.4 0.19 11.7 14.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 GAM23841.1 - 0.13 12.6 14.2 0.26 11.6 14.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 GAM23841.1 - 0.86 9.5 14.3 1.6 8.6 14.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DEP PF00610.21 GAM23843.1 - 3.5e-06 27.0 0.0 1.4e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PP2C_2 PF13672.6 GAM23843.1 - 0.0028 17.3 0.0 0.16 11.6 0.1 2.5 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 GAM23843.1 - 0.098 12.6 0.1 0.92 9.4 0.0 2.3 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DAP3 PF10236.9 GAM23844.1 - 2.5e-28 99.2 0.2 2.7e-26 92.5 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 GAM23844.1 - 0.00028 20.9 0.0 0.0015 18.5 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 GAM23844.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 GAM23844.1 - 0.13 11.9 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 GAM23845.1 - 1.4e-05 25.6 1.5 3.2e-05 24.5 0.1 2.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAM23845.1 - 0.00014 21.2 0.0 0.00034 19.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 GAM23845.1 - 0.0016 18.6 0.1 0.0053 16.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAM23845.1 - 0.002 18.4 0.1 0.0049 17.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 GAM23845.1 - 0.0075 16.6 0.1 0.13 12.7 0.1 3.1 2 1 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 GAM23845.1 - 0.02 14.8 0.2 0.091 12.7 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase Rad17 PF03215.15 GAM23845.1 - 0.03 14.2 0.2 0.1 12.5 0.2 1.9 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_16 PF13191.6 GAM23845.1 - 0.053 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 GAM23845.1 - 0.073 12.8 1.1 0.44 10.3 0.1 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 GAM23845.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 GAM23845.1 - 0.14 11.9 0.2 0.48 10.1 0.2 2.1 1 1 0 1 1 1 0 Cytidylate kinase AAA_25 PF13481.6 GAM23845.1 - 0.34 10.5 0.7 0.67 9.5 0.7 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM23845.1 - 0.83 10.2 7.8 0.2 12.2 1.5 2.7 2 1 0 2 2 2 0 ABC transporter CbiA PF01656.23 GAM23845.1 - 6.2 6.9 5.2 1.4 9.0 1.2 1.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cofilin_ADF PF00241.20 GAM23846.1 - 2e-15 56.7 0.0 3.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 GAM23846.1 - 1e-14 53.9 0.2 2.5e-14 52.6 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM23846.1 - 1.2e-13 50.7 0.5 2.3e-13 49.8 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 GAM23846.1 - 1.4e-13 50.3 0.0 7.8e-13 47.9 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Macoilin PF09726.9 GAM23847.1 - 0.043 12.4 3.3 0.049 12.2 3.3 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 GAM23847.1 - 0.35 10.4 13.1 0.47 10.0 13.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LRR_9 PF14580.6 GAM23848.1 - 4.7e-67 224.9 3.0 5.5e-67 224.6 3.0 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 GAM23848.1 - 6.8e-11 42.2 30.9 0.00011 22.5 5.4 3.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM23848.1 - 8.2e-08 31.9 12.0 2.4e-07 30.4 5.1 3.0 1 1 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 GAM23848.1 - 0.0097 15.9 6.5 17 5.8 0.0 4.8 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 GAM23848.1 - 1.4 9.8 12.6 41 5.3 0.0 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat VWA PF00092.28 GAM23849.1 - 5.5e-09 36.5 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM23849.1 - 2.7e-08 34.4 0.1 7.4e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain LRR_8 PF13855.6 GAM23850.1 - 1.5e-21 75.9 17.0 3.7e-09 36.2 0.9 3.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAM23850.1 - 2.3e-21 75.5 25.0 1e-06 28.9 1.4 5.8 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) C2 PF00168.30 GAM23850.1 - 8.9e-17 61.3 0.0 1.9e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain LRR_1 PF00560.33 GAM23850.1 - 1.6e-05 24.8 18.1 8.2 7.4 0.0 8.6 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 GAM23850.1 - 0.0037 17.2 18.6 13 6.1 0.2 7.8 8 0 0 8 8 8 1 Leucine Rich repeat LRR_9 PF14580.6 GAM23850.1 - 0.0066 16.0 15.2 0.57 9.7 0.4 3.9 3 1 1 4 4 4 3 Leucine-rich repeat AIP3 PF03915.13 GAM23850.1 - 0.011 14.9 0.1 0.016 14.4 0.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 EGF_2 PF07974.13 GAM23851.1 - 4.7e-05 23.7 15.0 0.00011 22.5 15.0 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 GAM23851.1 - 0.0008 19.4 8.9 0.0023 17.9 8.9 1.9 1 0 0 1 1 1 1 Tenascin EGF domain EGF_alliinase PF04863.13 GAM23851.1 - 3.1 8.3 8.1 14 6.2 6.7 2.6 2 1 0 2 2 2 0 Alliinase EGF-like domain TFIIA PF03153.13 GAM23852.1 - 7.3 6.5 29.1 16 5.3 29.1 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydrolase_6 PF13344.6 GAM23853.1 - 2.8e-21 75.5 0.0 1.4e-20 73.3 0.0 2.2 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM23853.1 - 9.1e-16 57.7 0.1 2.6e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 GAM23853.1 - 0.042 13.9 0.0 0.82 9.7 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM23853.1 - 0.11 12.7 0.0 6.5 7.0 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Myb_DNA-binding PF00249.31 GAM23855.1 - 0.0044 17.2 0.0 0.0096 16.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SUV3_C PF12513.8 GAM23856.1 - 6.3e-12 45.2 0.1 1.9e-11 43.7 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 GAM23856.1 - 7e-11 42.4 0.0 2.3e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 GAM23856.1 - 6.3e-07 29.2 0.0 1.6e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DUF5096 PF17019.5 GAM23856.1 - 0.042 13.6 0.3 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5096) SR-25 PF10500.9 GAM23856.1 - 0.73 9.4 6.0 1.6 8.3 6.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Complex1_LYR PF05347.15 GAM23857.1 - 2.5e-13 49.9 0.1 3.2e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 GAM23857.1 - 0.0018 18.8 0.0 0.0022 18.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 GAM23857.1 - 0.0056 17.4 0.1 0.0071 17.1 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Chromo PF00385.24 GAM23858.1 - 4.2e-05 23.4 2.0 8.2e-05 22.4 2.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.19 GAM23858.1 - 0.0048 16.6 1.6 0.012 15.4 1.6 1.7 1 0 0 1 1 1 1 AT hook motif SLC12 PF03522.15 GAM23858.1 - 0.36 9.8 5.7 0.52 9.3 5.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 GAM23858.1 - 0.61 8.3 10.9 0.77 8.0 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 GAM23858.1 - 1.6 8.4 15.5 2.3 7.8 15.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 GAM23858.1 - 2.3 6.3 14.3 3 6.0 14.3 1.1 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 GAM23858.1 - 3.9 6.2 21.5 5.8 5.7 21.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 GAM23858.1 - 9.2 4.7 20.2 11 4.5 20.2 1.1 1 0 0 1 1 1 0 Macoilin family ABC_tran PF00005.27 GAM23859.1 - 1.2e-20 74.5 1.3 5.3e-14 52.9 0.0 2.7 3 0 0 3 3 3 2 ABC transporter GerD PF17898.1 GAM23859.1 - 0.03 14.3 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 Spore germination GerD central core domain Apt1 PF10351.9 GAM23860.1 - 0.061 12.2 11.1 0.082 11.8 11.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Utp14 PF04615.13 GAM23860.1 - 0.23 10.0 3.2 0.23 10.0 3.2 1.1 1 0 0 1 1 1 0 Utp14 protein DUF2970 PF11174.8 GAM23860.1 - 0.33 10.8 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) TMEM154 PF15102.6 GAM23860.1 - 0.4 10.6 0.0 0.4 10.6 0.0 4.3 3 1 1 4 4 4 0 TMEM154 protein family SPX PF03105.19 GAM23860.1 - 0.83 9.5 13.3 0.94 9.3 13.3 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 GAM23860.1 - 1.2 7.6 12.8 1.5 7.3 12.8 1.3 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 GAM23860.1 - 5.3 4.0 14.4 5.4 4.0 14.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CFIA_Pcf11 PF11526.8 GAM23861.1 - 0.0022 18.4 15.8 0.0023 18.4 15.8 1.0 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 Secretin_N_2 PF07655.13 GAM23861.1 - 2.1 8.9 25.0 2.5 8.7 25.0 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Orf78 PF06024.12 GAM23861.1 - 5.8 7.3 14.0 7.3 6.9 14.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) PIG-X PF08320.12 GAM23862.1 - 7.3e-29 101.2 3.4 6.4e-27 94.8 3.4 2.3 1 1 0 1 1 1 1 PIG-X / PBN1 Pkinase_Tyr PF07714.17 GAM23863.1 - 3.1e-61 206.9 0.0 4.6e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM23863.1 - 1.4e-52 178.7 0.0 2.9e-52 177.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 GAM23863.1 - 4.9e-08 33.5 0.1 0.24 12.3 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM23863.1 - 0.00064 20.0 0.0 0.23 11.8 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_fungal PF17667.1 GAM23863.1 - 0.0023 16.8 0.1 0.0042 15.9 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Nup160 PF11715.8 GAM23863.1 - 0.029 13.0 0.1 0.11 11.1 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ribosomal_60s PF00428.19 GAM23864.1 - 9.4e-23 80.6 16.3 1.2e-22 80.3 16.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.8 GAM23864.1 - 2.8 6.4 10.5 3 6.3 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) G-alpha PF00503.20 GAM23865.1 - 1.4e-100 336.9 6.1 2.3e-100 336.2 6.1 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM23865.1 - 5e-15 55.4 1.8 7.3e-11 41.8 0.7 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM23865.1 - 5.4e-05 22.7 0.4 0.024 14.0 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM23865.1 - 5.8e-05 23.3 0.4 0.13 12.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RPW8 PF05659.11 GAM23866.1 - 0.0059 16.3 6.1 0.6 9.8 0.0 3.2 1 1 2 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 AKNA PF12443.8 GAM23866.1 - 0.013 16.1 1.8 0.034 14.8 0.9 2.2 1 1 0 1 1 1 0 AT-hook-containing transcription factor DivIVA PF05103.13 GAM23866.1 - 0.028 14.5 1.6 0.028 14.5 1.6 2.7 2 1 1 3 3 3 0 DivIVA protein DUF713 PF05218.14 GAM23866.1 - 0.12 12.1 7.4 0.026 14.2 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF713) DivIC PF04977.15 GAM23866.1 - 0.18 11.6 11.0 1 9.1 0.4 3.5 3 1 1 4 4 4 0 Septum formation initiator WEMBL PF05701.11 GAM23866.1 - 0.32 9.6 12.2 0.71 8.5 12.1 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light TACC_C PF05010.14 GAM23866.1 - 0.45 10.3 10.9 0.2 11.4 5.7 2.1 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FlaC_arch PF05377.11 GAM23866.1 - 0.86 10.0 6.4 5.6 7.4 0.3 3.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 GAM23866.1 - 0.99 9.6 12.7 0.77 10.0 7.7 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 GAM23866.1 - 1 9.6 9.0 1 9.6 4.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Plk4_PB2 PF18409.1 GAM23866.1 - 1.2 9.8 5.0 1.9 9.2 1.5 2.8 2 2 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 YabA PF06156.13 GAM23866.1 - 1.3 9.7 10.0 38 5.0 5.8 3.3 2 1 1 3 3 3 0 Initiation control protein YabA DUF948 PF06103.11 GAM23866.1 - 1.8 8.9 5.4 3.3 8.0 2.7 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 GAM23866.1 - 1.8 7.1 9.1 0.95 8.0 6.8 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fez1 PF06818.15 GAM23866.1 - 2.5 8.5 10.0 6.6 7.1 10.2 1.6 1 1 0 1 1 1 0 Fez1 Prominin PF05478.11 GAM23866.1 - 3.5 5.5 8.3 1.2 7.0 3.6 2.1 1 1 0 2 2 2 0 Prominin Sec34 PF04136.15 GAM23866.1 - 3.7 7.4 9.3 3.3 7.6 0.9 2.9 2 1 0 3 3 3 0 Sec34-like family PRKG1_interact PF15898.5 GAM23866.1 - 4.7 8.2 10.5 3.2 8.7 6.6 2.4 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 GAM23866.1 - 7.1 6.7 11.5 1.8 8.6 7.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 GAM23866.1 - 7.2 7.0 13.0 0.65 10.4 6.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Proteasome PF00227.26 GAM23867.1 - 1.2e-32 113.0 0.0 1.4e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Herpes_Helicase PF02689.14 GAM23867.1 - 0.19 9.6 0.0 0.29 9.0 0.0 1.2 1 0 0 1 1 1 0 Helicase Endonuclease_5 PF04493.14 GAM23868.1 - 1.9e-65 220.3 0.0 2.5e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 GAM23868.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF99 Ecl1 PF12855.7 GAM23868.1 - 0.015 16.5 4.9 0.022 15.9 4.9 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins MGC-24 PF05283.11 GAM23868.1 - 1.3 9.5 8.2 0.29 11.6 4.8 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SSP160 PF06933.11 GAM23868.1 - 1.5 6.9 12.9 2.2 6.4 12.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 GAM23868.1 - 2.5 8.1 9.4 5.7 6.9 9.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FSA_C PF10479.9 GAM23868.1 - 7.4 4.6 7.0 13 3.8 7.0 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ank_2 PF12796.7 GAM23869.1 - 6.3e-12 45.9 13.1 0.064 13.8 0.1 10.4 8 3 4 12 12 12 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM23869.1 - 2.7e-08 33.9 11.8 1.7 9.1 1.0 10.1 10 2 1 11 11 11 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM23869.1 - 0.00083 19.6 12.9 16 6.4 0.0 10.5 13 0 0 13 13 13 1 Ankyrin repeat Ank_4 PF13637.6 GAM23869.1 - 0.0019 18.7 11.7 21 5.8 0.4 8.3 9 0 0 9 9 9 2 Ankyrin repeats (many copies) Cwf_Cwc_15 PF04889.12 GAM23869.1 - 0.0085 15.9 1.3 0.0085 15.9 1.3 1.7 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Glyoxalase PF00903.25 GAM23870.1 - 3.9e-09 36.8 0.1 2.5e-07 31.0 0.1 2.8 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAM23870.1 - 0.00031 21.0 0.0 0.81 10.0 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 GAM23870.1 - 0.023 14.9 0.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal BcrAD_BadFG PF01869.20 GAM23872.1 - 1.6e-39 136.0 0.1 1.8e-39 135.9 0.1 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 GAM23872.1 - 2.8e-05 23.7 0.1 0.0029 17.2 0.2 2.1 2 0 0 2 2 2 2 ROK family Hydant_A_N PF05378.13 GAM23872.1 - 0.079 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Myb_DNA-binding PF00249.31 GAM23873.1 - 0.0009 19.4 0.2 0.0023 18.1 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM23873.1 - 0.0048 17.1 0.2 0.019 15.2 0.2 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAM23874.1 - 1.1e-07 31.9 0.0 3.8e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain ASXH PF13919.6 GAM23875.1 - 2.5e-05 24.3 0.3 0.00061 19.8 0.1 2.8 1 1 0 1 1 1 1 Asx homology domain NAD_binding_10 PF13460.6 GAM23876.1 - 1.1e-10 41.8 0.1 2.5e-09 37.3 0.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAM23876.1 - 2.7e-10 40.2 0.1 1.6e-08 34.4 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 GAM23876.1 - 0.00063 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 GAM23876.1 - 0.0011 18.0 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM23876.1 - 0.0011 18.5 0.1 0.0022 17.5 0.0 1.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAM23876.1 - 0.0063 16.6 0.4 0.018 15.1 0.2 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 GAM23876.1 - 0.017 14.6 0.2 0.069 12.6 0.1 1.9 1 1 1 2 2 2 0 short chain dehydrogenase Aa_trans PF01490.18 GAM23877.1 - 3.7e-12 45.7 32.3 7.2e-12 44.7 32.3 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAM23877.1 - 8.3e-08 31.7 17.5 8.3e-08 31.7 17.5 2.4 1 1 1 2 2 2 2 Tryptophan/tyrosine permease family Dicty_spore_N PF04562.12 GAM23878.1 - 4.3e-39 133.7 52.5 3.1e-22 79.4 21.5 4.8 4 1 0 4 4 4 2 Dictyostelium spore coat protein, N terminus Pho88 PF10032.9 GAM23879.1 - 4.3e-35 120.6 0.2 7.6e-35 119.8 0.2 1.4 1 1 0 1 1 1 1 Phosphate transport (Pho88) RPN6_N PF18055.1 GAM23880.1 - 2.7e-25 89.0 1.9 8.7e-24 84.1 0.5 2.7 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 GAM23880.1 - 8.7e-19 68.0 0.8 1.5e-17 64.0 0.1 3.0 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 GAM23880.1 - 0.00049 19.8 0.2 0.00049 19.8 0.2 2.2 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 GAM23880.1 - 0.014 15.6 1.5 2.2 8.6 0.2 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat RasGEF PF00617.19 GAM23882.1 - 9e-55 185.6 0.4 1.4e-52 178.5 0.0 2.8 2 0 0 2 2 2 1 RasGEF domain LRR_8 PF13855.6 GAM23882.1 - 1.5e-36 124.0 38.0 6.5e-10 38.6 2.1 6.7 3 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 GAM23882.1 - 2.4e-31 107.2 30.1 3.7e-06 27.2 0.2 8.0 6 1 1 7 7 7 7 Leucine Rich repeats (2 copies) RasGEF_N PF00618.20 GAM23882.1 - 2.6e-24 85.5 2.8 3e-24 85.3 0.7 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif LRR_1 PF00560.33 GAM23882.1 - 0.00062 20.0 26.8 31 5.6 0.0 11.0 10 2 0 10 10 10 0 Leucine Rich Repeat LRR_5 PF13306.6 GAM23882.1 - 0.011 15.6 2.6 0.78 9.7 0.1 3.0 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) IQ PF00612.27 GAM23882.1 - 0.027 14.3 15.9 0.1 12.4 5.9 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif Importin_rep_6 PF18829.1 GAM23882.1 - 0.067 13.3 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Importin repeat 6 SNF2_N PF00176.23 GAM23882.1 - 0.1 11.3 0.1 0.16 10.6 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain LRR_6 PF13516.6 GAM23882.1 - 0.17 12.0 26.2 2.4 8.4 0.1 8.7 9 0 0 9 9 9 0 Leucine Rich repeat Oxysterol_BP PF01237.18 GAM23883.1 - 1e-104 350.3 0.7 1.4e-104 349.9 0.7 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Wzt_C PF14524.6 GAM23883.1 - 0.061 13.3 0.0 0.28 11.2 0.0 1.9 1 1 1 2 2 2 0 Wzt C-terminal domain GDP_Man_Dehyd PF16363.5 GAM23884.1 - 2.8e-153 510.2 0.0 3.1e-153 510.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAM23884.1 - 3.3e-72 242.8 0.0 4.2e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM23884.1 - 0.0091 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 GAM23884.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family PI3_PI4_kinase PF00454.27 GAM23885.1 - 2.9e-52 178.0 0.1 9.2e-52 176.3 0.1 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 GAM23885.1 - 6.6e-43 147.1 14.1 2.3e-35 122.3 2.8 3.0 3 0 0 3 3 3 2 NUC194 domain FAT PF02259.23 GAM23885.1 - 2.7e-15 56.5 3.5 2.7e-15 56.5 3.5 2.3 2 0 0 2 2 2 1 FAT domain FATC PF02260.20 GAM23885.1 - 2.1e-11 43.4 0.5 5.4e-11 42.1 0.5 1.7 1 0 0 1 1 1 1 FATC domain RXT2_N PF08595.11 GAM23885.1 - 0.016 15.3 7.0 0.19 11.7 3.7 2.9 2 0 0 2 2 2 0 RXT2-like, N-terminal PHD20L1_u1 PF16660.5 GAM23885.1 - 0.38 11.5 3.6 1.1 10.0 2.0 2.6 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 TPR_2 PF07719.17 GAM23885.1 - 0.57 10.4 3.1 9.1 6.7 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat CobT PF06213.12 GAM23885.1 - 0.57 9.5 11.3 1.2 8.5 11.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF5520 PF17658.1 GAM23885.1 - 0.66 9.0 3.6 1.2 8.2 3.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5520) Vfa1 PF08432.10 GAM23885.1 - 0.93 9.8 7.1 3.9 7.8 7.1 2.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CLASP_N PF12348.8 GAM23885.1 - 1.1 8.8 6.8 5.8 6.4 0.1 4.2 4 0 0 4 4 4 0 CLASP N terminal NOA36 PF06524.12 GAM23885.1 - 1.5 8.0 13.4 3.1 7.0 13.4 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3276 PF11680.8 GAM23885.1 - 2.1 8.5 10.9 6.7 6.9 10.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Endotoxin_C PF03944.14 GAM23886.1 - 0.073 13.4 0.0 0.097 13.0 0.0 1.1 1 0 0 1 1 1 0 delta endotoxin Endotoxin_N PF03945.14 GAM23887.1 - 5.1e-37 127.7 3.8 6.4e-37 127.4 3.8 1.1 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.14 GAM23889.1 - 1.3e-44 152.6 4.0 2.1e-44 151.9 4.0 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain DIL PF01843.19 GAM23890.1 - 1.5e-21 76.6 0.9 4.1e-21 75.2 0.1 2.2 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 GAM23890.1 - 8.9e-07 28.2 3.6 0.00063 19.3 0.2 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif UPF0242 PF06785.11 GAM23890.1 - 0.0017 18.5 4.6 0.004 17.3 4.6 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 GAM23890.1 - 0.0053 15.9 8.1 0.013 14.6 8.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 GAM23890.1 - 0.01 16.0 4.0 0.052 13.7 4.0 2.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Geminin PF07412.12 GAM23890.1 - 0.017 14.9 0.2 0.017 14.9 0.2 2.0 2 0 0 2 2 2 0 Geminin Cep57_CLD_2 PF14197.6 GAM23890.1 - 0.02 15.0 3.4 0.07 13.2 3.4 1.9 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 GAM23890.1 - 0.056 13.5 5.3 0.12 12.4 5.3 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Uds1 PF15456.6 GAM23890.1 - 0.091 12.9 6.6 0.25 11.5 6.6 1.7 1 0 0 1 1 1 0 Up-regulated During Septation Spectrin PF00435.21 GAM23890.1 - 0.17 12.4 2.6 0.38 11.2 2.6 1.6 1 0 0 1 1 1 0 Spectrin repeat DUF4201 PF13870.6 GAM23890.1 - 0.25 11.1 10.5 1.5 8.5 3.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Flu_B_M2 PF04772.12 GAM23890.1 - 0.28 11.4 2.9 1.8 8.8 0.1 3.1 3 0 0 3 3 3 0 Influenza B matrix protein 2 (BM2) YabA PF06156.13 GAM23890.1 - 0.3 11.8 4.9 1.1 10.0 2.8 2.8 2 0 0 2 2 2 0 Initiation control protein YabA DHR10 PF18595.1 GAM23890.1 - 0.31 11.1 8.7 0.86 9.7 8.7 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain TolA_bind_tri PF16331.5 GAM23890.1 - 1.6 8.9 11.5 3.1 7.9 9.7 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation KLRAQ PF10205.9 GAM23890.1 - 2.6 8.3 14.1 0.12 12.6 7.4 2.3 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Methyltransf_11 PF08241.12 GAM23891.1 - 4.1e-20 72.2 0.0 5.9e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM23891.1 - 5.8e-18 65.4 0.0 9.8e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM23891.1 - 3.6e-14 52.8 0.0 4.8e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM23891.1 - 4.5e-14 53.0 0.0 8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM23891.1 - 9e-14 51.6 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM23891.1 - 2.1e-09 37.1 0.0 3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 GAM23891.1 - 0.0004 19.8 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 GAM23891.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Aminotran_3 PF00202.21 GAM23892.1 - 6.2e-78 262.2 0.0 8.2e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAM23892.1 - 5.8e-05 22.4 0.0 0.00074 18.8 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class I and II Peptidase_S10 PF00450.22 GAM23893.1 - 3.8e-118 395.5 0.4 4.3e-118 395.3 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase_Tyr PF07714.17 GAM23894.1 - 7.1e-55 186.1 0.0 1.1e-54 185.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM23894.1 - 3.7e-50 170.7 0.0 1.1e-49 169.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Serglycin PF04360.12 GAM23894.1 - 4 7.4 11.1 1.2 9.1 0.7 2.6 2 0 0 2 2 2 0 Serglycin Kelch_6 PF13964.6 GAM23895.1 - 1.1e-39 133.5 3.1 9.2e-08 32.1 0.0 7.0 3 2 4 7 7 7 5 Kelch motif Kelch_1 PF01344.25 GAM23895.1 - 1.8e-33 113.9 3.8 3.6e-09 36.0 0.0 6.7 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 GAM23895.1 - 5.9e-29 99.8 5.6 1.7e-05 24.7 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM23895.1 - 9.2e-29 98.9 8.2 3.4e-05 23.7 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAM23895.1 - 1.2e-25 89.3 4.4 0.00081 19.6 0.0 7.7 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM23895.1 - 1.2e-21 75.7 7.1 6.4e-05 22.8 0.0 6.5 7 1 0 7 7 7 4 Kelch motif F-box-like PF12937.7 GAM23895.1 - 3.9e-08 33.1 0.0 7.5e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM23895.1 - 4.4e-07 29.6 0.0 7.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAM23895.1 - 0.0015 18.4 0.1 0.0034 17.2 0.1 1.6 1 0 0 1 1 1 1 F-box Elongin_A PF06881.11 GAM23895.1 - 0.022 15.3 0.1 0.039 14.5 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A V-SNARE_C PF12352.8 GAM23896.1 - 1.8e-05 24.9 4.1 3.7e-05 23.9 4.1 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec34 PF04136.15 GAM23896.1 - 0.016 15.1 0.7 0.33 10.8 0.3 2.2 1 1 1 2 2 2 0 Sec34-like family DUF5316 PF17247.2 GAM23896.1 - 0.062 13.3 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5316) DUF2967 PF11179.8 GAM23896.1 - 0.25 9.4 0.5 0.33 9.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) GAPES2 PF17156.4 GAM23897.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Topoisom_I PF01028.20 GAM23898.1 - 4.6e-93 310.7 3.0 4.6e-93 310.7 3.0 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 GAM23898.1 - 6.4e-89 297.1 2.5 6.4e-89 297.1 2.5 3.1 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 GAM23898.1 - 1.4e-30 105.0 0.3 4.6e-30 103.4 0.3 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain Methyltransf_12 PF08242.12 GAM23899.1 - 3e-17 63.2 0.0 2e-16 60.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM23899.1 - 3.7e-17 62.6 0.0 8.4e-17 61.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM23899.1 - 1.1e-14 54.8 0.0 3.4e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM23899.1 - 1.3e-13 51.0 0.0 4.7e-13 49.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM23899.1 - 8.3e-13 48.8 0.0 2.2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM23899.1 - 1.4e-07 31.1 0.0 4.5e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 GAM23899.1 - 8.1e-06 25.3 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_8 PF05148.15 GAM23899.1 - 5.6e-05 23.1 0.1 0.00034 20.5 0.1 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 GAM23899.1 - 0.00015 21.3 0.0 0.00036 20.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 GAM23899.1 - 0.0016 17.9 2.0 0.017 14.6 0.0 3.2 1 1 1 2 2 2 1 Putative methyltransferase DUF938 PF06080.12 GAM23899.1 - 0.012 15.4 0.0 0.029 14.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Met_10 PF02475.16 GAM23899.1 - 0.014 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein LMBR1 PF04791.16 GAM23900.1 - 6.4e-41 140.8 38.6 3.2e-31 108.8 10.1 2.0 1 1 0 2 2 2 2 LMBR1-like membrane protein ASC PF00858.24 GAM23900.1 - 0.26 10.2 0.5 0.79 8.6 0.1 2.0 3 0 0 3 3 3 0 Amiloride-sensitive sodium channel IMPDH PF00478.25 GAM23901.1 - 5.7e-132 439.9 4.1 6.7e-132 439.7 4.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 GAM23901.1 - 2.2e-13 50.4 0.1 7.9e-08 32.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 GAM23901.1 - 7.2e-10 38.8 4.3 3.7e-06 26.6 2.5 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 GAM23901.1 - 1.9e-06 27.2 1.6 1.7e-05 24.0 1.9 2.1 2 1 0 2 2 2 1 FMN-dependent dehydrogenase ThiG PF05690.14 GAM23901.1 - 0.00032 20.1 0.1 0.00067 19.0 0.1 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 GAM23901.1 - 0.00045 19.7 1.7 0.0014 18.1 0.3 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.17 GAM23901.1 - 0.032 13.4 0.4 0.064 12.4 0.4 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 GAM23901.1 - 0.034 13.3 0.4 0.094 11.9 0.4 1.7 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase PcrB PF01884.17 GAM23901.1 - 0.052 13.0 1.1 24 4.3 0.0 3.9 4 0 0 4 4 4 0 PcrB family GST_C_3 PF14497.6 GAM23903.1 - 1.7e-19 69.8 0.0 3.6e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM23903.1 - 2.3e-09 37.5 0.0 4.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM23903.1 - 4.3e-08 33.3 0.0 7.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM23903.1 - 1.1e-05 25.3 0.1 2.3e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAM23903.1 - 0.0003 20.5 0.1 0.0024 17.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM23903.1 - 0.026 15.0 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Cortex-I_coil PF09304.10 GAM23904.1 - 1.9e-38 130.9 22.2 1.9e-38 130.9 22.2 2.9 1 1 0 2 2 2 1 Cortexillin I, coiled coil CH PF00307.31 GAM23904.1 - 1.2e-19 70.5 0.0 5e-17 62.0 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain DUF1902 PF08972.11 GAM23904.1 - 0.042 13.9 0.4 2.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) PIG-S PF10510.9 GAM23904.1 - 0.22 10.3 4.8 0.29 9.9 4.8 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein CENP-F_leu_zip PF10473.9 GAM23904.1 - 4.3 7.4 33.4 0.033 14.2 10.6 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Band_7 PF01145.25 GAM23904.1 - 5.3 7.0 6.8 11 6.0 6.8 1.5 1 0 0 1 1 1 0 SPFH domain / Band 7 family LMBR1 PF04791.16 GAM23904.1 - 7.2 5.4 7.2 11 4.8 7.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CH PF00307.31 GAM23905.1 - 1.2e-13 51.1 0.0 1.4e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM23905.1 - 0.037 13.9 0.0 0.091 12.6 0.0 1.6 1 1 0 1 1 1 0 CAMSAP CH domain RIFIN PF02009.16 GAM23906.1 - 0.27 11.1 2.3 0.4 10.5 2.3 1.3 1 0 0 1 1 1 0 Rifin FNIP PF05725.12 GAM23907.1 - 2.1e-58 194.2 25.2 5.8e-14 52.0 0.2 6.8 6 2 1 7 7 7 6 FNIP Repeat LRR_8 PF13855.6 GAM23907.1 - 0.0037 17.0 1.3 0.027 14.2 0.0 3.1 3 1 0 3 3 3 1 Leucine rich repeat Crystallin PF00525.18 GAM23907.1 - 0.093 12.9 1.1 0.63 10.3 0.1 2.9 2 1 2 4 4 4 0 Alpha crystallin A chain, N terminal Ras PF00071.22 GAM23908.1 - 8.1e-57 191.3 0.0 9.4e-57 191.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM23908.1 - 1.7e-20 73.4 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM23908.1 - 3.4e-09 36.4 0.0 4.5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM23908.1 - 0.0006 19.4 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM23908.1 - 0.0018 18.2 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase DUF3776 PF12618.8 GAM23908.1 - 0.022 15.3 0.1 0.037 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) Syntaxin-18_N PF10496.9 GAM23908.1 - 0.025 14.8 0.1 0.062 13.6 0.1 1.7 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus LcrG PF07216.12 GAM23908.1 - 0.088 12.7 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 LcrG protein AAA_25 PF13481.6 GAM23908.1 - 0.093 12.3 0.0 0.45 10.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAM23908.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase eIF2A PF08662.11 GAM23909.1 - 5.6e-56 189.5 7.4 1.3e-51 175.2 0.6 4.2 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 GAM23909.1 - 6.9e-06 25.8 0.2 6.9e-06 25.8 0.2 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 GAM23909.1 - 9.4e-05 22.6 0.6 0.43 10.9 0.0 5.1 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Methyltr_RsmF_N PF17125.5 GAM23909.1 - 0.013 16.0 1.5 7.8 7.1 0.1 4.1 2 2 2 4 4 4 0 N-terminal domain of 16S rRNA methyltransferase RsmF IKI3 PF04762.12 GAM23909.1 - 0.013 13.5 0.0 0.053 11.5 0.0 1.8 1 1 1 2 2 2 0 IKI3 family DUF943 PF06092.12 GAM23909.1 - 0.026 14.2 0.1 0.24 11.0 0.0 2.6 3 0 0 3 3 3 0 Enterobacterial putative membrane protein (DUF943) Glyco_transf_10 PF00852.19 GAM23910.1 - 2.6e-37 128.2 0.1 4.7e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Laminin_G_3 PF13385.6 GAM23910.1 - 6.9e-17 62.0 0.1 1.4e-16 61.0 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF2418 PF10332.9 GAM23911.1 - 3.3e-15 56.4 1.3 7e-15 55.3 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Dicty_CAR PF05462.11 GAM23912.1 - 0.00039 19.7 15.1 0.00051 19.3 15.1 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor LSM PF01423.22 GAM23913.1 - 4e-19 68.1 0.0 5e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM23913.1 - 0.018 15.1 0.0 0.025 14.7 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain FNIP PF05725.12 GAM23914.1 - 2.2e-51 171.7 36.8 1.6e-12 47.3 1.3 8.1 4 2 3 8 8 8 7 FNIP Repeat DUF393 PF04134.12 GAM23915.1 - 1.3e-25 90.9 0.0 1.7e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Melibiase_2 PF16499.5 GAM23916.1 - 2.4e-102 341.9 3.8 2.9e-102 341.7 3.8 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 GAM23916.1 - 1.5e-15 57.0 1.2 2.2e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 GAM23916.1 - 3.7e-07 30.3 0.0 7.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 GAM23916.1 - 2e-05 23.7 0.0 4.8e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Melibiase MDM31_MDM32 PF08118.11 GAM23918.1 - 8.8e-93 311.7 2.3 1.4e-45 156.0 0.0 3.3 2 1 1 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins GPCR_chapero_1 PF11904.8 GAM23920.1 - 1.7e-50 172.2 0.3 2.6e-50 171.6 0.3 1.3 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 GAM23920.1 - 6.1e-06 26.7 0.1 2.9e-05 24.6 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM23920.1 - 0.0001 22.8 0.1 0.00021 21.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM23920.1 - 0.0042 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM23920.1 - 0.0077 16.7 0.1 0.12 13.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 GAM23920.1 - 0.094 13.2 0.4 0.23 12.0 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat DJ-1_PfpI PF01965.24 GAM23922.1 - 9.8e-49 165.3 0.0 1.1e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAM23922.1 - 0.00024 20.9 0.0 0.00055 19.7 0.0 1.7 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase PF00117.28 GAM23922.1 - 0.0003 20.6 0.0 0.0006 19.6 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Catalase_C PF18011.1 GAM23922.1 - 0.005 16.5 0.0 0.0076 15.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal domain found in long catalases GATase_3 PF07685.14 GAM23922.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.3 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 GAM23922.1 - 0.037 13.8 0.0 0.061 13.1 0.0 1.4 1 1 0 1 1 1 0 Peptidase C26 SNO PF01174.19 GAM23922.1 - 0.057 13.3 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family GATase_5 PF13507.6 GAM23922.1 - 0.21 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MEDS PF14417.6 GAM23923.1 - 0.094 12.5 0.0 0.18 11.7 0.0 1.3 1 1 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain EMP70 PF02990.16 GAM23924.1 - 4e-117 392.1 16.7 4e-117 392.1 16.7 1.2 1 1 0 1 1 1 1 Endomembrane protein 70 2OG-FeII_Oxy_3 PF13640.6 GAM23925.1 - 1.3e-08 35.6 0.0 2.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NAPRTase PF04095.16 GAM23925.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Adaptin_N PF01602.20 GAM23927.1 - 6.7e-66 222.9 9.3 1.2e-65 222.0 9.3 1.5 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.6 GAM23927.1 - 1.8e-12 47.5 0.0 5.7e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.7 GAM23927.1 - 3.4e-09 37.0 0.7 2.3e-08 34.2 0.0 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Coatomer_b_Cpla PF14806.6 GAM23927.1 - 0.00078 19.4 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform UME PF08064.13 GAM23927.1 - 0.25 11.3 3.0 0.69 9.9 0.1 3.0 3 1 0 3 3 3 0 UME (NUC010) domain Virul_fac_BrkB PF03631.15 GAM23928.1 - 2.3e-05 24.1 0.1 2.3e-05 24.1 0.1 1.7 2 0 0 2 2 2 1 Virulence factor BrkB GPR_Gpa2_C PF11970.8 GAM23928.1 - 0.00075 19.5 1.4 0.00075 19.5 1.4 2.3 3 1 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF996 PF06195.13 GAM23928.1 - 0.0082 16.4 1.7 0.0082 16.4 1.7 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF996) 7tm_1 PF00001.21 GAM23928.1 - 0.016 14.6 8.4 0.035 13.4 8.4 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2207 PF09972.9 GAM23928.1 - 0.34 9.6 4.7 0.089 11.5 1.6 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 GAM23928.1 - 2.5 8.2 9.1 3.1 7.9 0.9 2.4 2 1 0 2 2 2 0 DHHC palmitoyltransferase Cofilin_ADF PF00241.20 GAM23929.1 - 1.1e-08 34.9 0.2 1.4e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein ETC_C1_NDUFA5 PF04716.14 GAM23930.1 - 7.2e-22 77.0 0.3 1e-21 76.5 0.3 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Pox_mRNA-cap PF03341.13 GAM23930.1 - 0.02 14.2 0.1 0.025 13.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus mRNA capping enzyme, small subunit HECT PF00632.25 GAM23931.1 - 3e-71 240.4 1.1 5.3e-71 239.6 0.6 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.19 GAM23931.1 - 9e-18 65.0 0.4 1.7e-10 41.6 0.2 3.0 3 0 0 3 3 3 2 Filamin/ABP280 repeat Neurexophilin PF06312.12 GAM23931.1 - 0.0058 16.1 0.6 0.014 14.9 0.6 1.5 1 0 0 1 1 1 1 Neurexophilin Invasin_D3 PF09134.10 GAM23931.1 - 0.21 11.9 2.2 0.47 10.8 0.0 2.7 4 0 0 4 4 4 0 Invasin, domain 3 CASP_C PF08172.12 GAM23932.1 - 1.8e-62 211.0 8.6 1.8e-62 211.0 8.6 4.7 1 1 3 4 4 4 1 CASP C terminal ATG16 PF08614.11 GAM23932.1 - 0.0009 19.5 20.4 0.0009 19.5 20.4 6.1 2 1 4 6 6 6 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 GAM23932.1 - 0.002 18.2 8.2 0.002 18.2 8.2 5.8 4 1 2 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 GAM23932.1 - 0.017 15.5 50.1 0.038 14.4 2.3 8.1 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 GAM23932.1 - 0.018 14.7 70.3 0.011 15.5 30.5 4.7 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 GAM23932.1 - 0.042 13.3 0.0 0.042 13.3 0.0 5.9 4 1 1 5 5 5 0 Golgin subfamily A member 5 CENP-H PF05837.12 GAM23932.1 - 0.12 12.8 0.1 0.12 12.8 0.1 6.0 4 1 2 6 6 6 0 Centromere protein H (CENP-H) MAD PF05557.13 GAM23932.1 - 1.4 7.2 69.6 0.017 13.5 33.0 3.0 2 1 1 3 3 3 0 Mitotic checkpoint protein KASH_CCD PF14662.6 GAM23932.1 - 2.3 8.0 76.3 0.11 12.3 23.9 4.9 3 1 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH MFS_1 PF07690.16 GAM23933.1 - 1.1e-19 70.6 40.7 9.5e-12 44.5 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 GAM23933.1 - 4.5e-16 59.0 13.6 4.5e-16 59.0 13.6 3.3 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 GAM23933.1 - 5e-05 22.3 27.6 0.00044 19.2 10.2 3.9 2 2 1 4 4 4 2 MFS_1 like family Ubie_methyltran PF01209.18 GAM23934.1 - 2.1e-16 60.0 0.0 5.7e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAM23934.1 - 1.9e-15 57.3 0.0 3.4e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM23934.1 - 4.5e-14 52.9 0.0 7.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM23934.1 - 1.9e-11 44.0 0.0 6.7e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM23934.1 - 2.4e-10 40.5 0.0 3.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM23934.1 - 4.2e-09 37.1 0.0 8.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 GAM23934.1 - 0.0022 17.2 0.0 0.0045 16.1 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 GAM23934.1 - 0.0053 16.3 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 GAM23934.1 - 0.0077 16.0 0.0 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 GAM23934.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 GAM23934.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 GAM23934.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAM23935.1 - 1.3e-16 61.0 0.0 2.2e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM23935.1 - 3.7e-16 59.6 0.0 5.7e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM23935.1 - 5.7e-16 58.6 0.0 4e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAM23935.1 - 5.4e-10 39.3 0.0 9.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM23935.1 - 3e-08 34.3 0.0 5.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM23935.1 - 5.6e-07 29.5 0.0 8.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAM23935.1 - 0.006 16.0 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 GAM23935.1 - 0.035 13.2 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 GAM23935.1 - 0.044 13.3 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 GAM23935.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_32 PF13679.6 GAM23935.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 GAM23935.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_25 PF13649.6 GAM23936.1 - 1.9e-16 60.6 0.0 3.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM23936.1 - 1.9e-16 60.5 0.0 3.7e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM23936.1 - 5.8e-13 48.7 0.0 7.8e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAM23936.1 - 6.8e-11 42.2 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM23936.1 - 7.6e-11 42.1 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM23936.1 - 3.2e-09 37.4 0.0 6.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 GAM23936.1 - 0.0017 17.5 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase TehB PF03848.14 GAM23936.1 - 0.0025 17.3 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 GAM23936.1 - 0.005 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAM23936.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 GAM23936.1 - 0.034 13.9 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 GAM23936.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF1870 PF08965.10 GAM23937.1 - 0.21 11.6 2.4 0.51 10.4 0.1 2.3 2 1 0 3 3 3 0 Domain of unknown function (DUF1870) DUF179 PF02622.15 GAM23938.1 - 2.4e-33 115.3 0.0 3.2e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 dsrm PF00035.26 GAM23939.1 - 0.0014 19.3 0.0 0.0036 18.0 0.0 1.7 1 1 0 1 1 1 1 Double-stranded RNA binding motif eRF1_2 PF03464.15 GAM23940.1 - 1.2e-44 151.8 0.0 1.9e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAM23940.1 - 1.3e-35 122.3 0.0 3e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 GAM23940.1 - 1.7e-19 70.1 0.0 2.7e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 GAM23940.1 - 4.3e-08 33.5 0.0 6.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 GAM23940.1 - 3e-07 30.8 0.0 4.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor GST_C_3 PF14497.6 GAM23941.1 - 4.8e-19 68.4 0.0 7.9e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM23941.1 - 7.8e-11 42.2 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM23941.1 - 1e-07 32.0 0.0 1.6e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM23941.1 - 1e-05 25.8 0.0 2.8e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM23941.1 - 0.012 15.6 0.1 0.024 14.6 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain E1-E2_ATPase PF00122.20 GAM23942.1 - 9.8e-46 155.6 3.2 2.9e-45 154.0 3.2 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAM23942.1 - 2.6e-41 141.3 3.2 2.6e-41 141.3 3.2 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAM23942.1 - 1.2e-22 81.2 0.1 1.7e-12 48.1 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM23942.1 - 2.1e-15 56.1 0.0 5.3e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAM23942.1 - 1e-06 28.7 0.1 0.058 13.5 0.0 3.0 2 1 1 3 3 3 2 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM23942.1 - 2e-05 24.4 1.8 0.0019 18.0 0.3 3.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAM23942.1 - 0.07 13.5 0.0 0.5 10.7 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3040 PF11239.8 GAM23942.1 - 0.22 11.8 5.0 0.12 12.6 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF1772 PF08592.11 GAM23942.1 - 0.42 10.9 0.0 0.42 10.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Mito_carr PF00153.27 GAM23943.1 - 9.2e-63 208.2 1.9 6.8e-21 74.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase_Tyr PF07714.17 GAM23944.1 - 8.4e-60 202.2 0.0 1.6e-59 201.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM23944.1 - 1.1e-47 162.7 0.0 2.2e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 GAM23944.1 - 9.7e-27 94.0 0.0 2.3e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 GAM23944.1 - 2.5e-08 34.1 0.0 1.5e-07 31.6 0.0 2.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase PQQ_3 PF13570.6 GAM23944.1 - 0.033 14.7 0.0 0.22 12.1 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain FNIP PF05725.12 GAM23945.1 - 8.2e-61 202.0 27.9 1.1e-14 54.3 0.2 9.4 4 2 4 10 10 10 10 FNIP Repeat DUF1769 PF08588.10 GAM23945.1 - 0.0032 17.6 6.8 6.8 7.0 0.0 5.2 5 1 1 6 6 6 3 Protein of unknown function (DUF1769) BLOC1S3 PF15753.5 GAM23945.1 - 0.083 13.0 3.9 0.18 11.9 3.9 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 TFIIA PF03153.13 GAM23945.1 - 9.1 6.2 19.7 16 5.3 19.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP PF05725.12 GAM23946.1 - 1.6e-50 169.0 39.8 1.6e-14 53.8 0.9 9.8 7 3 3 10 10 10 9 FNIP Repeat DUF1769 PF08588.10 GAM23946.1 - 0.0019 18.3 5.6 0.22 11.8 0.0 5.3 4 2 3 7 7 7 1 Protein of unknown function (DUF1769) LRR_1 PF00560.33 GAM23946.1 - 0.13 12.9 10.2 32 5.6 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat FNIP PF05725.12 GAM23947.1 - 4.8e-05 23.4 1.8 0.0091 16.1 0.5 3.0 1 1 1 2 2 2 2 FNIP Repeat Tyrosinase PF00264.20 GAM23948.1 - 4.8e-34 118.6 5.7 9.8e-34 117.6 5.7 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase Complex1_LYR PF05347.15 GAM23950.1 - 4.2e-13 49.1 1.4 5.8e-13 48.7 1.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAM23950.1 - 0.0065 17.2 0.6 0.0092 16.7 0.5 1.3 1 1 0 1 1 1 1 Complex1_LYR-like GalP_UDP_tr_C PF02744.17 GAM23951.1 - 0.0073 16.0 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain p450 PF00067.22 GAM23952.1 - 1.3e-101 340.7 0.0 1.6e-101 340.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3522 PF12036.8 GAM23954.1 - 3.2e-46 158.0 8.6 4.1e-46 157.6 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) MMM1 PF10296.9 GAM23955.1 - 1.5e-11 43.9 1.3 2.7e-08 33.2 0.1 3.1 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 UBA PF00627.31 GAM23956.1 - 6e-10 38.8 0.5 6e-10 38.8 0.5 1.7 2 0 0 2 2 2 1 UBA/TS-N domain Rhomboid PF01694.22 GAM23956.1 - 0.00013 22.0 8.2 0.00016 21.7 8.2 1.1 1 0 0 1 1 1 1 Rhomboid family E3_UbLigase_EDD PF11547.8 GAM23956.1 - 0.0095 15.6 0.3 0.021 14.5 0.3 1.6 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD TssN PF17555.2 GAM23956.1 - 0.062 12.7 4.8 0.094 12.1 4.8 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN UBA_3 PF09288.10 GAM23956.1 - 0.099 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain UBA_4 PF14555.6 GAM23956.1 - 0.11 12.4 0.2 0.25 11.2 0.2 1.6 1 0 0 1 1 1 0 UBA-like domain Actin PF00022.19 GAM23957.1 - 4.6e-32 111.1 0.0 2.8e-25 88.8 0.0 3.0 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 GAM23957.1 - 1.1e-08 34.7 5.4 0.0002 20.6 0.0 3.1 3 0 0 3 3 3 2 Putative actin-like family FtsA PF14450.6 GAM23957.1 - 0.98 9.9 0.0 0.98 9.9 0.0 3.1 3 1 0 3 3 3 0 Cell division protein FtsA MHC_II_beta PF00969.19 GAM23957.1 - 2 8.6 3.8 8.3 6.6 2.2 2.4 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain SecE PF00584.20 GAM23958.1 - 5.4e-17 61.5 0.1 6.1e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CbtB PF09489.10 GAM23958.1 - 0.085 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) RIBIOP_C PF04950.12 GAM23959.1 - 1.4e-85 287.3 0.3 1.4e-85 287.3 0.3 2.5 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAM23959.1 - 5.4e-31 106.5 1.6 1.2e-30 105.4 0.0 2.6 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 GAM23959.1 - 2.1e-06 27.4 0.7 0.00024 20.7 0.0 3.0 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM23959.1 - 1.4e-05 25.1 0.3 8.9e-05 22.5 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 GAM23959.1 - 0.0037 17.0 0.1 0.01 15.6 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 GAM23959.1 - 0.0048 17.2 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAM23959.1 - 0.0056 17.1 0.0 0.023 15.1 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAM23959.1 - 0.0065 16.6 0.0 0.0065 16.6 0.0 2.5 3 0 0 3 3 1 1 AAA domain AAA_14 PF13173.6 GAM23959.1 - 0.022 14.8 1.2 0.052 13.6 0.0 2.3 2 0 0 2 2 1 0 AAA domain FeoB_N PF02421.18 GAM23959.1 - 0.053 13.1 0.1 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 GAM23959.1 - 0.1 12.9 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 GAM23959.1 - 0.27 11.8 0.0 0.27 11.8 0.0 3.2 3 0 0 3 3 3 0 ABC transporter Pkinase_Tyr PF07714.17 GAM23960.1 - 9.7e-50 169.3 0.0 1.6e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM23960.1 - 3.2e-45 154.6 0.0 5.4e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 GAM23960.1 - 2.9e-26 91.5 6.2 2.4e-06 28.0 0.0 6.5 3 2 4 7 7 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM23960.1 - 2.8e-25 88.7 3.5 1e-09 38.9 0.7 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM23960.1 - 8e-21 73.8 2.1 5.3e-07 29.8 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM23960.1 - 8.7e-20 68.7 2.8 0.00097 19.4 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 GAM23960.1 - 3.7e-18 65.1 1.3 0.0021 18.4 0.4 5.7 5 0 0 5 5 5 3 Ankyrin repeat SAM_1 PF00536.30 GAM23960.1 - 3.4e-12 46.6 0.2 1e-11 45.1 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM23960.1 - 1.9e-10 40.7 0.2 4.3e-10 39.6 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Alpha-2-MRAP_C PF06401.11 GAM23960.1 - 0.011 15.7 0.5 0.011 15.7 0.5 1.7 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Haspin_kinase PF12330.8 GAM23960.1 - 0.025 13.5 5.3 2.1 7.2 5.2 2.5 1 1 0 1 1 1 0 Haspin like kinase domain Radical_SAM_N PF08497.10 GAM23960.1 - 0.13 11.5 0.2 0.24 10.6 0.2 1.3 1 0 0 1 1 1 0 Radical SAM N-terminal APH PF01636.23 GAM23960.1 - 0.19 11.6 0.1 0.4 10.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FNIP PF05725.12 GAM23961.1 - 1.8e-57 191.2 16.3 1.2e-13 50.9 0.1 8.3 5 2 2 8 8 8 7 FNIP Repeat ATP-synt_10 PF05176.14 GAM23963.1 - 5.7e-34 117.5 0.0 7.8e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein UbiA PF01040.18 GAM23964.1 - 1.4e-27 96.6 11.2 1.9e-27 96.2 11.2 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family DHHC PF01529.20 GAM23964.1 - 7.9 6.6 9.5 0.49 10.5 1.0 2.8 1 1 0 2 2 2 0 DHHC palmitoyltransferase CTP_transf_like PF01467.26 GAM23965.1 - 3.1e-30 105.3 0.1 6.4e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 GAM23965.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5639) WD40 PF00400.32 GAM23966.1 - 3.8e-14 52.9 12.3 8.1e-07 29.7 0.3 5.5 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM23966.1 - 0.031 14.6 0.8 0.57 10.5 0.1 3.0 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAM23966.1 - 0.039 14.5 0.0 0.27 11.8 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain Ebp2 PF05890.12 GAM23967.1 - 4.5e-73 246.1 39.6 4.5e-73 246.1 39.6 2.7 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF2547 PF10818.8 GAM23970.1 - 0.75 10.8 5.5 0.2 12.6 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) DUF2756 PF10956.8 GAM23970.1 - 1.1 9.7 7.5 0.38 11.3 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) Endonuclease_NS PF01223.23 GAM23971.1 - 8.7e-37 127.1 2.0 5.9e-21 75.3 3.3 2.2 1 1 1 2 2 2 2 DNA/RNA non-specific endonuclease Exog_C PF18026.1 GAM23971.1 - 0.0011 18.9 0.1 0.0021 18.1 0.1 1.5 1 0 0 1 1 1 1 Endo/exonuclease (EXOG) C-terminal domain PIP5K PF01504.18 GAM23972.1 - 5.3e-95 317.8 0.1 1e-94 316.8 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase V-SNARE_C PF12352.8 GAM23973.1 - 3e-15 56.3 3.7 3.8e-15 55.9 2.3 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAM23973.1 - 7.3e-07 29.0 0.4 7.3e-07 29.0 0.4 2.5 2 1 0 3 3 3 1 Sec20 DUF3853 PF12964.7 GAM23973.1 - 0.041 14.0 0.1 0.089 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Rx_N PF18052.1 GAM23973.1 - 0.054 13.8 3.6 0.97 9.8 0.0 2.8 1 1 0 2 2 2 0 Rx N-terminal domain NPV_P10 PF05531.12 GAM23973.1 - 0.09 13.3 5.9 10 6.7 0.6 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Imm42 PF15593.6 GAM23973.1 - 0.41 11.1 7.8 0.061 13.8 3.6 1.7 2 1 0 2 2 2 0 Immunity protein 42 DUF5094 PF17015.5 GAM23973.1 - 1.2 9.2 14.4 0.68 10.0 9.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5094) FapA PF03961.13 GAM23973.1 - 2.4 6.7 12.1 0.48 9.0 7.7 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A Sporozoite_P67 PF05642.11 GAM23973.1 - 4.7 5.2 8.7 7.1 4.6 8.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1899 PF08953.11 GAM23974.1 - 3.8e-42 142.0 4.4 1.4e-20 72.9 0.1 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF1899) WD40_4 PF16300.5 GAM23974.1 - 4.7e-29 100.0 1.4 3.5e-17 62.0 0.3 2.5 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 GAM23974.1 - 1.7e-26 92.0 13.1 0.00094 20.0 0.0 9.3 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM23974.1 - 9.2e-08 32.3 0.5 0.23 11.8 0.0 6.0 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1652 PF07865.11 GAM23974.1 - 0.00079 19.2 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1652) eIF2A PF08662.11 GAM23974.1 - 0.0018 18.2 0.1 4.7 7.0 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IgG_binding_B PF01378.17 GAM23974.1 - 0.021 14.9 0.2 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 B domain IKI3 PF04762.12 GAM23974.1 - 0.039 12.0 1.8 0.19 9.7 0.0 2.4 2 1 1 3 3 3 0 IKI3 family PH PF00169.29 GAM23975.1 - 3.4e-16 59.7 0.6 4.7e-16 59.2 0.6 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM23975.1 - 3.3e-10 40.3 0.3 4.7e-10 39.8 0.3 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAM23975.1 - 0.00027 21.1 1.6 0.0021 18.3 0.4 2.1 1 1 1 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 GAM23975.1 - 0.0013 19.1 0.1 0.0023 18.3 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGAP PF00620.27 GAM23976.1 - 4.6e-25 88.2 1.7 8.2e-25 87.4 0.7 1.9 2 0 0 2 2 2 1 RhoGAP domain GPP34 PF05719.11 GAM23977.1 - 1.2e-05 25.4 0.0 1.5e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Mob1_phocein PF03637.17 GAM23977.1 - 0.0016 18.5 0.3 0.003 17.6 0.3 1.5 1 0 0 1 1 1 1 Mob1/phocein family Ferrochelatase PF00762.19 GAM23977.1 - 0.0037 16.4 0.1 0.0053 15.9 0.1 1.3 1 0 0 1 1 1 1 Ferrochelatase RNase_J_C PF17770.1 GAM23977.1 - 0.23 12.5 2.5 0.75 10.9 0.2 2.4 1 1 2 3 3 3 0 Ribonuclease J C-terminal domain MIEAP PF16026.5 GAM23977.1 - 0.42 10.8 2.7 0.78 9.9 2.6 1.5 1 1 0 1 1 1 0 Mitochondria-eating protein RRM_1 PF00076.22 GAM23978.1 - 8.1e-11 41.6 0.1 1.5e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 GAM23978.1 - 9.8e-06 25.5 3.4 2.5e-05 24.1 3.4 1.8 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 GAM23978.1 - 0.00042 21.0 0.0 0.00042 21.0 0.0 2.4 2 0 0 2 2 2 1 Torus domain zf-CCCH PF00642.24 GAM23978.1 - 0.0014 18.5 1.9 0.0014 18.5 1.9 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 GAM23978.1 - 0.0073 16.5 0.7 0.0073 16.5 0.7 1.9 2 0 0 2 2 2 1 Zinc-finger containing family DUF3445 PF11927.8 GAM23978.1 - 0.023 14.3 0.5 0.036 13.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) FYVE PF01363.21 GAM23978.1 - 0.037 14.2 0.9 0.037 14.2 0.9 2.2 2 0 0 2 2 2 0 FYVE zinc finger RRM_3 PF08777.11 GAM23978.1 - 0.039 14.0 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 RNA binding motif zf-CCCH_4 PF18044.1 GAM23978.1 - 0.056 13.3 4.0 0.15 11.9 4.0 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger DUF4834 PF16118.5 GAM23978.1 - 0.21 12.6 3.8 0.47 11.5 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Menin PF05053.13 GAM23978.1 - 0.21 9.9 6.3 0.29 9.5 6.3 1.1 1 0 0 1 1 1 0 Menin DUF3306 PF11748.8 GAM23978.1 - 0.43 11.5 5.2 1.4 9.8 4.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) ALMT PF11744.8 GAM23978.1 - 0.62 8.8 2.7 0.88 8.3 2.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Spt20 PF12090.8 GAM23978.1 - 0.75 9.4 12.8 1.3 8.5 12.8 1.4 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 GAM23978.1 - 1.8 7.2 6.7 2.6 6.7 6.7 1.1 1 0 0 1 1 1 0 Presenilin BPS1 PF05633.11 GAM23979.1 - 4.2 6.3 5.1 0.76 8.7 0.5 1.8 2 0 0 2 2 2 0 Protein BYPASS1-related tRNA-synt_1 PF00133.22 GAM23980.1 - 1.8e-185 617.7 0.0 3.9e-184 613.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM23980.1 - 1.4e-26 93.3 0.2 2.4e-26 92.5 0.2 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM23980.1 - 1.2e-18 67.0 0.1 3.4e-09 35.9 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAM23980.1 - 6.9e-11 42.0 0.0 1.7e-06 27.7 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAM23980.1 - 1.6e-06 27.7 0.0 0.089 12.1 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 GAM23980.1 - 0.029 13.7 0.1 0.093 12.0 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) tRNA-synt_1d PF00750.19 GAM23980.1 - 0.034 13.1 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) MIT PF04212.18 GAM23981.1 - 2.9e-24 84.9 14.2 2.5e-13 49.9 1.8 2.3 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain LIM PF00412.22 GAM23981.1 - 0.0023 18.1 0.3 0.0043 17.2 0.3 1.4 1 0 0 1 1 1 1 LIM domain TOM20_plant PF06552.12 GAM23981.1 - 0.91 9.2 4.0 1.9 8.2 4.0 1.5 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_2 PF07719.17 GAM23981.1 - 3.8 7.9 9.4 1.9 8.8 1.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat CbiQ PF02361.16 GAM23982.1 - 0.41 10.2 17.9 0.53 9.9 17.9 1.1 1 0 0 1 1 1 0 Cobalt transport protein DUF334 PF03904.13 GAM23982.1 - 0.55 9.7 8.7 0.7 9.4 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Tetraspanin PF00335.20 GAM23982.1 - 0.91 9.2 27.2 2.1 8.0 24.3 2.4 1 1 2 3 3 3 0 Tetraspanin family Nop53 PF07767.11 GAM23983.1 - 9e-33 114.2 37.0 1.2e-32 113.8 37.0 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF1659 PF07872.11 GAM23983.1 - 0.89 9.3 3.2 0.65 9.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) FA_desaturase PF00487.24 GAM23984.1 - 4.5e-16 59.5 21.3 2.4e-14 53.8 21.3 2.3 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 GAM23984.1 - 1.4e-07 31.7 0.0 2.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) LRR_4 PF12799.7 GAM23985.1 - 0.0037 17.6 19.5 0.049 14.1 0.1 5.1 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAM23985.1 - 0.0088 16.0 0.1 0.0088 16.0 0.1 7.5 8 0 0 8 8 8 3 Leucine Rich repeat F-box PF00646.33 GAM23985.1 - 0.027 14.4 0.2 0.62 10.0 0.0 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 GAM23985.1 - 0.063 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like BORCS8 PF10167.9 GAM23986.1 - 5.9e-33 113.2 5.4 5.9e-33 113.2 5.4 1.8 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 8 Spem1 PF15670.5 GAM23986.1 - 0.086 12.4 5.3 0.023 14.3 1.3 1.9 1 1 1 2 2 2 0 Spermatid maturation protein 1 Nre_C PF04895.12 GAM23986.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.8 1 1 0 1 1 1 0 Archaeal Nre, C-terminal DHC PF09626.10 GAM23986.1 - 1.3 9.9 6.6 1.5 9.8 0.4 3.2 2 2 2 4 4 4 0 Dihaem cytochrome c SWI-SNF_Ssr4 PF08549.10 GAM23986.1 - 8.7 4.8 15.6 9.8 4.7 15.6 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) BLOC1_2 PF10046.9 GAM23987.1 - 4e-05 23.8 3.7 4e-05 23.8 3.7 4.8 2 2 1 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Motilin_ghrelin PF04644.12 GAM23987.1 - 0.059 13.2 0.9 2.8 7.8 0.4 2.8 2 0 0 2 2 2 0 Motilin/ghrelin ERM PF00769.19 GAM23987.1 - 0.076 12.8 53.6 0.15 11.9 23.4 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF812 PF05667.11 GAM23987.1 - 0.11 11.4 51.4 0.098 11.5 32.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Fez1 PF06818.15 GAM23987.1 - 0.15 12.5 51.5 1.5 9.3 21.2 2.4 1 1 1 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 GAM23987.1 - 0.36 10.8 61.5 0.065 13.2 21.5 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 GAM23987.1 - 0.48 10.2 46.8 0.29 10.9 9.1 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF724) MAD PF05557.13 GAM23987.1 - 0.87 7.9 56.6 3.2 6.0 25.8 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Leu_zip PF15294.6 GAM23987.1 - 2.2 7.8 54.5 2.2 7.7 17.4 3.2 1 1 2 3 3 3 0 Leucine zipper CALCOCO1 PF07888.11 GAM23987.1 - 2.4 6.9 51.4 0.52 9.1 46.5 1.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3138 PF11336.8 GAM23987.1 - 4.4 5.8 9.3 0.25 9.9 3.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF4055 PF13264.6 GAM23987.1 - 6.6 6.9 14.3 0.85 9.8 0.6 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4055) TACC_C PF05010.14 GAM23987.1 - 6.7 6.4 51.1 0.067 13.0 9.6 3.3 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spc7 PF08317.11 GAM23987.1 - 7.9 5.3 61.3 1 8.2 22.0 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein ParBc PF02195.18 GAM23988.1 - 0.67 10.3 3.0 1 9.7 0.5 2.4 2 1 1 3 3 3 0 ParB-like nuclease domain Allexi_40kDa PF05549.11 GAM23988.1 - 1.4 8.4 18.8 0.79 9.2 6.8 3.3 3 1 0 3 3 3 0 Allexivirus 40kDa protein DUF5560 PF17715.1 GAM23988.1 - 3.3 7.1 7.4 2.2 7.7 1.0 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5560) Yos1 PF08571.10 GAM23989.1 - 1.2e-19 70.3 2.9 1.4e-19 70.1 2.9 1.1 1 0 0 1 1 1 1 Yos1-like Apolipoprotein PF01442.18 GAM23990.1 - 0.00043 20.2 3.0 0.00055 19.9 3.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 GAM23990.1 - 0.00063 20.2 1.9 0.078 13.5 1.7 2.4 1 1 0 1 1 1 1 YtxH-like protein Pex19 PF04614.12 GAM23990.1 - 0.23 11.2 9.7 0.34 10.6 9.7 1.3 1 0 0 1 1 1 0 Pex19 protein family Peptidase_C1 PF00112.23 GAM23991.1 - 3.8e-72 242.9 3.6 3.8e-72 242.9 3.6 1.6 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM23991.1 - 6.5e-12 45.7 6.3 1.1e-11 44.9 6.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAM23991.1 - 1.8e-05 23.7 0.5 0.026 13.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_M32 PF02074.15 GAM23991.1 - 0.041 12.7 1.0 0.058 12.2 1.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DEAD PF00270.29 GAM23992.1 - 2.1e-51 174.2 0.0 5.4e-51 172.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM23992.1 - 3.3e-22 78.9 0.1 1.1e-21 77.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 GAM23992.1 - 1.5e-11 44.4 8.5 1.5e-11 44.4 8.5 4.0 4 1 1 5 5 5 1 DBP10CT (NUC160) domain Alba PF01918.21 GAM23993.1 - 2.7e-10 39.9 0.0 5.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 GAM23993.1 - 1.3e-05 25.2 0.1 0.018 15.0 0.0 2.7 1 1 1 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P FSA_C PF10479.9 GAM23993.1 - 0.0085 14.3 3.3 0.0087 14.2 3.3 1.1 1 0 0 1 1 1 1 Fragile site-associated protein C-terminus SSP160 PF06933.11 GAM23993.1 - 0.061 11.5 16.7 0.079 11.2 16.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3123 PF11321.8 GAM23993.1 - 0.18 12.5 4.9 0.066 13.9 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Sporozoite_P67 PF05642.11 GAM23993.1 - 0.74 7.8 7.1 0.86 7.6 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MGC-24 PF05283.11 GAM23993.1 - 3.6 8.0 12.5 0.3 11.5 7.3 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PRR18 PF15671.5 GAM23993.1 - 8.4 6.2 11.6 14 5.4 11.6 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 Mucin PF01456.17 GAM23993.1 - 9.6 6.2 28.1 18 5.3 28.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein adh_short PF00106.25 GAM23994.1 - 2.3e-33 115.3 0.1 4.7e-33 114.3 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM23994.1 - 4.6e-22 78.7 0.0 7.6e-22 78.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM23994.1 - 6.1e-05 23.0 0.1 9.9e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAM23994.1 - 0.033 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 GAM23994.1 - 0.077 12.9 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Ldh_1_N PF00056.23 GAM23994.1 - 0.17 12.0 0.5 0.9 9.6 0.3 2.2 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Branch_AA_trans PF05525.13 GAM23994.1 - 0.42 9.4 3.1 4.1 6.2 0.1 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport protein DSPc PF00782.20 GAM23995.1 - 4.8e-28 97.6 0.9 1e-27 96.6 0.9 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 GAM23995.1 - 2.1e-06 28.2 0.5 0.00038 20.9 0.2 3.0 2 1 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.6 GAM23995.1 - 0.00026 21.1 0.0 0.00057 20.0 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 GAM23995.1 - 0.024 14.2 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 GAM23995.1 - 0.03 14.6 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain Gp-FAR-1 PF05823.12 GAM23995.1 - 0.056 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Pilin_GH PF16734.5 GAM23995.1 - 0.082 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Type IV pilin-like G and H, putative Apolipoprotein PF01442.18 GAM23997.1 - 4.1e-18 66.0 49.3 2.6e-08 34.0 9.5 5.7 3 2 2 5 5 5 4 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 GAM23997.1 - 6.1e-07 29.6 72.4 0.17 11.9 14.4 8.0 4 2 4 8 8 8 4 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 GAM23997.1 - 7.5e-05 22.8 44.7 0.035 14.1 4.4 6.9 3 2 3 7 7 7 3 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 GAM23997.1 - 0.0007 19.6 20.2 1.9 8.4 2.8 8.0 4 3 3 8 8 7 2 Apolipoprotein O Prominin PF05478.11 GAM23997.1 - 0.00091 17.3 52.5 0.0057 14.7 3.5 5.2 3 2 1 4 4 4 2 Prominin Syntaxin_2 PF14523.6 GAM23997.1 - 0.0093 16.3 1.8 0.0093 16.3 1.8 8.0 4 3 3 7 7 7 1 Syntaxin-like protein CorA PF01544.18 GAM23997.1 - 0.011 15.1 1.7 0.011 15.1 1.7 3.9 3 1 1 4 4 4 0 CorA-like Mg2+ transporter protein DUF883 PF05957.13 GAM23997.1 - 0.025 15.2 43.5 4.8 7.9 3.6 9.3 3 2 6 10 10 10 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.10 GAM23997.1 - 0.064 13.4 17.5 1.8 8.7 0.0 6.8 3 2 2 7 7 7 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Coat_F PF07875.12 GAM23997.1 - 0.068 13.4 1.2 5.8 7.2 0.1 3.1 2 0 0 2 2 2 0 Coat F domain UPF0147 PF03685.13 GAM23997.1 - 0.089 12.9 0.1 0.089 12.9 0.1 5.0 5 1 0 5 5 5 0 Uncharacterised protein family (UPF0147) YtxH PF12732.7 GAM23997.1 - 0.19 12.2 69.0 1.7 9.3 7.0 10.9 2 2 3 5 5 4 0 YtxH-like protein DUF842 PF05811.13 GAM23997.1 - 0.22 11.2 23.7 0.74 9.5 0.6 5.5 4 1 1 5 5 5 0 Eukaryotic protein of unknown function (DUF842) CdvA PF18822.1 GAM23997.1 - 0.38 10.6 49.2 0.31 10.9 1.9 8.3 4 3 4 8 8 8 0 CdvA-like coiled-coil domain DUF2884 PF11101.8 GAM23997.1 - 1.3 8.5 44.7 0.021 14.3 13.4 4.8 3 1 0 4 4 4 0 Protein of unknown function (DUF2884) Phasin PF05597.11 GAM23997.1 - 2.5 8.1 52.9 0.4 10.7 0.4 7.9 4 3 5 9 9 9 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ImmE5 PF11480.8 GAM23997.1 - 3.7 8.1 6.1 3.4 8.2 0.0 3.8 3 0 0 3 3 3 0 Colicin-E5 Imm protein PIN_8 PF18476.1 GAM23997.1 - 5.1 6.9 53.4 1.5 8.6 4.0 6.2 3 2 2 6 6 6 0 PIN like domain DUF3619 PF12279.8 GAM23997.1 - 6.7 7.1 8.8 0.98 9.8 0.6 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3619) AtuA PF07287.11 GAM23998.1 - 7.4e-35 120.3 0.0 9e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Njmu-R1 PF15053.6 GAM23999.1 - 1.1e-27 97.1 10.8 5.6e-25 88.2 1.1 3.3 2 2 1 3 3 3 3 Mjmu-R1-like protein family DUF961 PF06125.11 GAM23999.1 - 0.075 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) BiPBP_C PF06832.12 GAM24000.1 - 0.0032 17.5 0.0 6 7.0 0.0 3.5 3 0 0 3 3 3 1 Penicillin-Binding Protein C-terminus Family Y_Y_Y PF07495.13 GAM24000.1 - 0.038 14.0 3.0 2.1 8.4 0.0 4.6 5 0 0 5 5 5 0 Y_Y_Y domain GAD-like PF08887.11 GAM24000.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 GAD-like domain DUF5011 PF16403.5 GAM24000.1 - 1.3 9.2 4.8 14 5.9 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5011) DUF2861 PF11060.8 GAM24002.1 - 0.13 11.8 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2861) BclA_C PF18573.1 GAM24002.1 - 1.7 8.6 9.3 0.18 11.7 0.6 3.5 4 0 0 4 4 4 0 BclA C-terminal domain FNIP PF05725.12 GAM24003.1 - 8.5e-09 35.4 6.3 1.7e-05 24.9 1.0 5.2 5 2 1 6 6 6 3 FNIP Repeat FNIP PF05725.12 GAM24004.1 - 0.065 13.4 3.2 1 9.6 0.0 2.9 3 1 0 3 3 3 0 FNIP Repeat Ins_allergen_rp PF06757.13 GAM24006.1 - 0.029 14.3 0.7 0.16 11.9 0.2 2.1 1 1 1 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification TIG PF01833.24 GAM24007.1 - 6.6e-11 42.1 37.1 0.00013 22.0 2.9 6.3 6 0 0 6 6 6 4 IPT/TIG domain EGF_2 PF07974.13 GAM24007.1 - 0.0031 17.8 16.0 0.008 16.5 16.0 1.7 1 0 0 1 1 1 1 EGF-like domain DUF1285 PF06938.11 GAM24007.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1285) I-EGF_1 PF18372.1 GAM24007.1 - 0.14 12.3 7.7 0.33 11.1 7.7 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Phage_holin_3_6 PF07332.11 GAM24007.1 - 0.18 11.9 0.1 0.29 11.2 0.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III EGF PF00008.27 GAM24007.1 - 0.21 11.9 11.0 0.51 10.7 11.0 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 GAM24007.1 - 0.6 10.2 14.1 0.34 11.0 10.9 2.3 2 0 0 2 2 2 0 Tenascin EGF domain hEGF PF12661.7 GAM24007.1 - 0.67 10.7 9.5 2.9 8.7 9.5 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF Kelch_6 PF13964.6 GAM24009.1 - 6.9e-09 35.7 4.0 9.7e-06 25.7 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM24009.1 - 1.6e-08 34.4 0.6 4.5e-05 23.4 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM24009.1 - 5.5e-05 22.7 0.7 0.0021 17.6 0.1 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 GAM24009.1 - 0.023 14.7 10.0 0.86 9.7 0.5 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.6 GAM24009.1 - 0.03 14.6 2.3 0.81 10.0 0.0 4.0 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM24009.1 - 0.62 10.1 5.5 1.3 9.1 0.1 3.3 4 0 0 4 4 4 0 Kelch motif FNIP PF05725.12 GAM24010.1 - 9.4e-60 198.5 23.2 7.3e-12 45.3 0.1 8.0 2 2 7 10 10 10 9 FNIP Repeat DUF1769 PF08588.10 GAM24010.1 - 0.012 15.8 3.2 7.3 6.9 0.1 4.9 4 2 1 5 5 5 0 Protein of unknown function (DUF1769) F-box-like PF12937.7 GAM24010.1 - 0.11 12.4 0.2 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 F-box-like Acyl-CoA_dh_1 PF00441.24 GAM24011.1 - 1.6e-46 158.2 0.4 2.3e-46 157.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAM24011.1 - 2.6e-29 102.2 0.0 5.4e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAM24011.1 - 3.5e-28 97.6 0.0 9.1e-28 96.3 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM24011.1 - 2e-19 70.2 0.0 3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HhH-GPD PF00730.25 GAM24011.1 - 0.038 14.4 0.0 0.11 13.0 0.0 1.7 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein HpaB_N PF11794.8 GAM24011.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal AhpC-TSA_2 PF13911.6 GAM24012.1 - 1.3e-18 67.2 0.0 2.4e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 GAM24012.1 - 6.9e-05 22.8 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAM24012.1 - 0.021 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Redoxin Flu_NS2 PF00601.19 GAM24012.1 - 0.14 12.5 0.6 0.29 11.4 0.6 1.4 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) YdjO PF14169.6 GAM24013.1 - 0.013 15.2 0.7 0.049 13.4 0.0 2.3 1 1 1 2 2 2 0 Cold-inducible protein YdjO Sugar_tr PF00083.24 GAM24014.1 - 7.5e-96 321.7 34.9 8.3e-95 318.3 34.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM24014.1 - 8.7e-40 136.7 62.1 1.1e-30 106.8 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MDD_C PF18376.1 GAM24015.1 - 1.1e-70 237.2 0.2 1.7e-70 236.6 0.2 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 GAM24015.1 - 3.6e-06 27.1 4.8 7.5e-06 26.1 4.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Metallophos PF00149.28 GAM24016.1 - 2.7e-14 54.1 0.6 3.4e-14 53.8 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM24016.1 - 3.5e-10 40.3 2.4 2.1e-09 37.8 2.4 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 GAM24016.1 - 3.9e-08 32.9 0.0 2.3e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily PTPS PF01242.19 GAM24017.1 - 7.5e-34 116.3 0.3 8.5e-34 116.2 0.3 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Kelch_1 PF01344.25 GAM24018.1 - 1.2e-31 108.0 14.3 1.6e-08 34.0 0.1 6.4 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 GAM24018.1 - 4.2e-31 106.2 19.7 2.4e-07 30.8 0.0 7.6 6 2 2 8 8 8 5 Kelch motif Kelch_2 PF07646.15 GAM24018.1 - 2.3e-28 97.1 7.2 4e-05 23.4 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GAM24018.1 - 2.7e-28 97.7 9.1 3.6e-05 23.7 0.4 6.7 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM24018.1 - 7.9e-25 86.4 12.5 2.1e-05 24.4 0.0 6.7 6 0 0 6 6 6 5 Kelch motif BTB PF00651.31 GAM24018.1 - 2.5e-24 85.7 2.2 9.9e-23 80.5 0.5 2.5 1 1 1 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 GAM24018.1 - 3.2e-23 81.5 22.9 2.3e-07 30.9 0.1 7.7 8 0 0 8 8 8 5 Galactose oxidase, central domain BACK PF07707.15 GAM24018.1 - 0.019 15.0 1.5 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 BTB And C-terminal Kelch RNA_pol_Rbc25 PF08292.12 GAM24018.1 - 0.13 12.6 0.2 0.59 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Pkinase_Tyr PF07714.17 GAM24019.1 - 2.7e-55 187.5 0.0 3.5e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM24019.1 - 1.4e-43 149.1 0.0 2.1e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 GAM24019.1 - 0.05 13.0 0.1 0.42 9.9 0.1 2.0 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM24019.1 - 0.065 12.2 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain SAP PF02037.27 GAM24020.1 - 0.0023 17.6 0.1 0.0048 16.6 0.1 1.5 1 0 0 1 1 1 1 SAP domain BUD22 PF09073.10 GAM24020.1 - 0.032 13.6 12.5 0.041 13.2 12.5 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GAM24020.1 - 0.06 11.6 13.2 0.072 11.3 13.2 1.0 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 GAM24020.1 - 0.08 13.1 11.4 0.11 12.6 11.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 GAM24020.1 - 0.16 11.3 12.7 0.2 11.0 12.7 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 GAM24020.1 - 0.43 8.8 8.1 0.51 8.6 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAM24020.1 - 1.7 6.7 17.2 2.2 6.3 17.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi IFT57 PF10498.9 GAM24020.1 - 2 7.3 10.3 2.9 6.8 10.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Roughex PF06020.11 GAM24020.1 - 2.7 7.0 11.1 3.6 6.6 11.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SURF2 PF05477.11 GAM24020.1 - 3.3 7.3 8.5 4.6 6.9 8.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TRAP_alpha PF03896.16 GAM24020.1 - 4.8 6.3 9.6 7.3 5.7 9.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Chromo PF00385.24 GAM24021.1 - 1.5e-14 53.7 0.5 1.5e-14 53.7 0.5 2.6 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GAM24021.1 - 0.00033 20.8 0.0 0.00074 19.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Peptidase_M24_C PF16188.5 GAM24021.1 - 0.066 13.3 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 RT_RNaseH PF17917.1 GAM24022.1 - 4.6e-23 81.5 0.4 1.5e-22 79.8 0.1 2.0 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAM24022.1 - 1.7e-20 72.9 0.6 4.6e-20 71.5 0.1 2.0 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAM24022.1 - 3e-10 40.0 0.7 5.6e-10 39.1 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 GAM24024.1 - 1.8e-23 82.8 0.1 2.8e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAM24024.1 - 5.9e-21 74.4 0.1 8.7e-21 73.8 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAM24025.1 - 0.00022 20.8 0.0 0.00022 20.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 GAM24026.1 - 1.5e-53 181.8 0.0 1.9e-52 178.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24026.1 - 6.6e-53 179.6 0.0 9.9e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RA PF00788.23 GAM24026.1 - 0.0005 20.6 0.0 0.0034 18.0 0.0 2.5 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Dicty_REP PF05086.12 GAM24026.1 - 0.014 13.4 13.0 0.027 12.5 13.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase_fungal PF17667.1 GAM24026.1 - 0.019 13.8 0.0 0.019 13.8 0.0 1.9 3 1 0 3 3 3 0 Fungal protein kinase APH PF01636.23 GAM24026.1 - 0.17 11.8 0.0 0.57 10.1 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3439 PF11921.8 GAM24026.1 - 6.3 6.8 15.5 20 5.2 12.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Hpt PF01627.23 GAM24027.1 - 2.6e-09 37.2 0.0 4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Hpt domain PPR_1 PF12854.7 GAM24027.1 - 0.0005 19.7 0.4 0.0005 19.7 0.4 1.8 2 0 0 2 2 2 1 PPR repeat PPR PF01535.20 GAM24027.1 - 0.029 14.6 0.2 0.029 14.6 0.2 2.1 2 0 0 2 2 2 0 PPR repeat Utp14 PF04615.13 GAM24027.1 - 0.33 9.5 18.5 0.36 9.4 18.5 1.1 1 0 0 1 1 1 0 Utp14 protein Hamartin PF04388.12 GAM24027.1 - 2.6 6.6 24.7 3.1 6.4 24.7 1.1 1 0 0 1 1 1 0 Hamartin protein MAJIN PF15077.6 GAM24027.1 - 8.9 6.0 15.2 15 5.3 15.2 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein SEC-C PF02810.15 GAM24028.1 - 1.2e-07 31.5 4.0 2.4e-07 30.5 4.0 1.5 1 0 0 1 1 1 1 SEC-C motif PseudoU_synth_2 PF00849.22 GAM24029.1 - 3.2e-13 50.1 0.5 1.5e-12 47.9 0.0 2.4 2 1 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 GAM24029.1 - 2e-06 27.4 0.1 5.5e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 S4 domain Nitr_red_assoc PF09655.10 GAM24029.1 - 1.9 9.1 5.4 2.1 9.0 3.1 2.1 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) PhoLip_ATPase_C PF16212.5 GAM24030.1 - 1.4e-63 215.0 22.7 1.4e-63 215.0 22.7 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM24030.1 - 2.7e-25 87.8 5.3 2.7e-25 87.8 5.3 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAM24030.1 - 5.6e-13 48.8 0.0 2e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM24030.1 - 6.3e-13 49.5 0.0 2.8e-06 27.8 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAM24030.1 - 3.7e-08 33.1 0.0 1.5e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAM24030.1 - 0.003 17.3 0.2 0.025 14.3 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.32 GAM24031.1 - 1.9 8.2 3.7 1.8 8.3 1.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 GAM24031.1 - 2 8.3 7.1 0.27 11.1 1.6 2.2 2 0 0 2 2 2 0 EF-hand domain pair PLDc_2 PF13091.6 GAM24032.1 - 1.5e-37 128.5 0.0 3.9e-23 81.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAM24032.1 - 3.1e-09 36.6 0.8 2.6e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif ArfGap PF01412.18 GAM24032.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf PPP4R2 PF09184.11 GAM24032.1 - 1.1 8.8 7.9 1.9 8.0 7.9 1.3 1 0 0 1 1 1 0 PPP4R2 GCP_N_terminal PF17681.1 GAM24033.1 - 1.1e-73 248.5 2.0 9.7e-73 245.5 0.0 2.9 3 0 0 3 3 3 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAM24033.1 - 3.4e-69 233.7 8.9 3.4e-69 233.7 8.9 2.2 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal DUF382 PF04037.13 GAM24033.1 - 0.049 13.8 2.2 0.36 11.0 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF382) 2OG-FeII_Oxy_3 PF13640.6 GAM24034.1 - 0.0022 18.8 0.0 0.0044 17.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Caprin-1_C PF12287.8 GAM24034.1 - 0.09 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Daxx PF03344.15 GAM24036.1 - 0.062 13.4 0.2 0.17 12.0 0.1 1.8 2 0 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain 2OG-FeII_Oxy_3 PF13640.6 GAM24037.1 - 0.0049 17.7 0.0 0.011 16.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 GAM24038.1 - 0.0037 17.8 2.0 0.29 11.8 0.5 4.2 3 2 1 5 5 5 1 Ankyrin repeats (3 copies) RYDR_ITPR PF01365.21 GAM24038.1 - 0.026 14.0 0.2 0.085 12.3 0.1 1.9 1 1 0 1 1 1 0 RIH domain LAGLIDADG_1 PF00961.19 GAM24038.1 - 0.11 13.5 1.4 21 6.1 0.0 3.5 3 0 0 3 3 3 0 LAGLIDADG endonuclease Peptidase_M66 PF10462.9 GAM24039.1 - 7.2e-80 268.2 1.0 9.3e-80 267.8 1.0 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_5 PF13688.6 GAM24039.1 - 0.0034 17.6 0.0 0.019 15.1 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Metallopep PF12044.8 GAM24039.1 - 0.0046 15.6 0.2 0.0072 15.0 0.2 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_4 PF13583.6 GAM24039.1 - 0.0055 16.4 0.1 0.0099 15.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAM24039.1 - 0.0055 17.2 0.1 0.014 15.9 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAM24039.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Matrixin ECSCR PF15820.5 GAM24039.1 - 0.14 12.0 0.2 0.28 11.0 0.2 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator 2OG-FeII_Oxy_3 PF13640.6 GAM24040.1 - 1.3e-08 35.7 0.0 6.6e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SDA1 PF05285.12 GAM24040.1 - 0.0049 16.3 13.9 0.0077 15.7 13.9 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 GAM24040.1 - 0.32 9.2 7.7 0.51 8.6 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 GAM24040.1 - 3 7.4 17.2 7.4 6.1 17.2 1.6 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 GAM24040.1 - 4.4 6.5 20.8 7.4 5.8 20.8 1.3 1 0 0 1 1 1 0 BUD22 2OG-FeII_Oxy_3 PF13640.6 GAM24041.1 - 6e-08 33.5 0.0 1.7e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DNA_pol_phi PF04931.13 GAM24041.1 - 0.0047 15.1 16.4 0.0085 14.3 16.4 1.3 1 0 0 1 1 1 1 DNA polymerase phi BSP_II PF05432.11 GAM24041.1 - 0.0056 16.4 10.9 0.0099 15.6 10.9 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF2457 PF10446.9 GAM24041.1 - 0.052 12.7 17.6 0.1 11.7 17.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 GAM24041.1 - 0.06 11.6 8.0 0.086 11.1 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GAM24041.1 - 0.075 11.8 1.1 0.11 11.2 1.1 1.1 1 0 0 1 1 1 0 Presenilin Nucleopor_Nup85 PF07575.13 GAM24041.1 - 0.12 11.0 0.1 0.17 10.4 0.1 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin BUD22 PF09073.10 GAM24041.1 - 0.25 10.7 16.3 0.44 9.8 15.3 1.7 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 GAM24041.1 - 0.62 9.4 15.6 1.1 8.6 15.6 1.3 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 GAM24041.1 - 1 7.8 9.9 0.6 8.6 7.6 1.6 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 FRQ PF09421.10 GAM24041.1 - 1.2 7.1 11.2 1.7 6.5 11.2 1.1 1 0 0 1 1 1 0 Frequency clock protein Nop14 PF04147.12 GAM24041.1 - 3.1 5.9 15.6 5.7 5.0 15.6 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 GAM24041.1 - 6.6 6.6 23.2 0.26 11.3 17.3 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit 2OG-FeII_Oxy_3 PF13640.6 GAM24042.1 - 5e-08 33.7 0.0 1.3e-07 32.4 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CDC45 PF02724.14 GAM24042.1 - 0.71 8.1 4.8 1.1 7.5 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GAM24042.1 - 1.1 7.7 6.9 1.6 7.1 6.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF393 PF04134.12 GAM24043.1 - 0.04 15.3 0.6 0.52 11.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF393 2OG-FeII_Oxy_3 PF13640.6 GAM24044.1 - 1.1e-07 32.6 0.0 2.7e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 GAM24045.1 - 2.4e-08 34.7 0.0 9e-08 32.9 0.0 2.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sporozoite_P67 PF05642.11 GAM24045.1 - 0.044 11.9 6.0 0.07 11.2 6.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 GAM24045.1 - 0.54 9.5 19.8 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 BUD22 TLP-20 PF06088.11 GAM24045.1 - 6 6.7 15.7 0.35 10.7 9.8 2.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) 2OG-FeII_Oxy_3 PF13640.6 GAM24046.1 - 1.3e-08 35.6 0.0 2.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2711 PF10924.8 GAM24046.1 - 0.044 13.4 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) NOA36 PF06524.12 GAM24046.1 - 3.8 6.8 5.7 6.7 5.9 5.7 1.3 1 0 0 1 1 1 0 NOA36 protein 2OG-FeII_Oxy_3 PF13640.6 GAM24047.1 - 3e-08 34.5 0.0 9.1e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SDA1 PF05285.12 GAM24047.1 - 0.15 11.5 27.1 0.24 10.8 27.1 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 GAM24047.1 - 1.1 8.0 6.3 1.6 7.4 6.3 1.2 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GAM24047.1 - 1.8 7.8 26.4 2.5 7.3 23.1 2.1 2 0 0 2 2 2 0 BUD22 2OG-FeII_Oxy_3 PF13640.6 GAM24048.1 - 3.7e-08 34.2 0.0 9.4e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VGLL4 PF15245.6 GAM24048.1 - 0.16 12.0 0.1 0.31 11.1 0.1 1.3 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 2OG-FeII_Oxy_3 PF13640.6 GAM24050.1 - 6.5e-08 33.4 0.0 1.6e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AbrB_C PF18277.1 GAM24050.1 - 0.061 13.0 0.1 0.49 10.1 0.0 2.6 2 0 0 2 2 2 0 AbrB C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 GAM24051.1 - 4.1e-08 34.0 0.0 2e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1687 PF07955.11 GAM24051.1 - 0.0066 16.9 0.0 0.058 13.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1687) BUD22 PF09073.10 GAM24051.1 - 3.9 6.7 6.7 3.1 7.0 5.1 1.5 2 0 0 2 2 2 0 BUD22 TIG PF01833.24 GAM24052.1 - 3.8e-12 46.1 58.2 8.2e-08 32.2 2.4 7.5 4 1 2 6 6 6 4 IPT/TIG domain RIFIN PF02009.16 GAM24052.1 - 1.1 9.1 2.7 1.9 8.3 2.7 1.3 1 0 0 1 1 1 0 Rifin PRR18 PF15671.5 GAM24052.1 - 2.6 7.9 10.7 5.9 6.7 10.7 1.5 1 0 0 1 1 1 0 Proline-rich protein family 18 TMEM154 PF15102.6 GAM24052.1 - 4 7.3 10.3 13 5.6 10.3 2.0 1 0 0 1 1 1 0 TMEM154 protein family TIG PF01833.24 GAM24053.1 - 3.1e-16 59.2 33.7 1.5e-06 28.1 3.1 6.6 3 2 3 6 6 6 6 IPT/TIG domain Kelch_6 PF13964.6 GAM24054.1 - 5.1e-35 118.6 12.9 1.2e-06 28.6 0.5 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 GAM24054.1 - 2.1e-34 117.3 20.2 1.6e-09 37.6 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM24054.1 - 1.2e-31 108.3 25.3 1.2e-07 31.9 0.0 7.4 8 0 0 8 8 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM24054.1 - 4e-31 106.5 8.8 9.1e-08 31.9 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 GAM24054.1 - 2.7e-29 100.0 19.2 4.2e-06 26.5 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 GAM24054.1 - 1.3e-26 91.9 10.6 4.7e-08 32.5 0.1 6.4 6 0 0 6 6 6 5 Kelch motif SAM_2 PF07647.17 GAM24054.1 - 1.6e-15 56.9 0.2 3.1e-15 56.0 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAM24054.1 - 3.7e-13 49.7 0.2 6.3e-13 49.0 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Raftlin PF15250.6 GAM24054.1 - 1.3 7.6 5.4 2.3 6.9 5.4 1.2 1 0 0 1 1 1 0 Raftlin Dicty_REP PF05086.12 GAM24054.1 - 2.3 6.1 14.2 3.4 5.5 14.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Asp PF00026.23 GAM24054.1 - 2.7 7.3 9.7 0.37 10.2 0.1 3.3 3 2 1 4 4 4 0 Eukaryotic aspartyl protease WD40 PF00400.32 GAM24055.1 - 6.9e-62 203.9 22.7 2.1e-10 41.0 0.5 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM24055.1 - 1.3e-18 67.1 1.7 1.1e-05 25.7 0.0 4.7 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM24055.1 - 1.1e-10 40.8 4.7 0.027 13.1 0.0 5.3 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAM24055.1 - 7.3e-06 25.0 1.3 0.016 14.0 0.0 3.3 3 1 1 4 4 4 2 Nup133 N terminal like Ge1_WD40 PF16529.5 GAM24055.1 - 7.1e-05 21.9 8.3 0.53 9.2 0.1 4.6 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 GAM24055.1 - 0.00039 20.3 0.2 0.00074 19.4 0.2 1.5 1 0 0 1 1 1 1 LisH FapA PF03961.13 GAM24055.1 - 0.056 12.1 1.2 0.081 11.5 1.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF241 PF03087.14 GAM24055.1 - 0.25 11.1 0.5 0.53 10.1 0.5 1.5 1 0 0 1 1 1 0 Arabidopsis protein of unknown function LSM PF01423.22 GAM24056.1 - 4.9e-13 48.6 1.1 4.9e-13 48.6 1.1 1.3 2 0 0 2 2 2 1 LSM domain DAHP_snth_FXD PF18152.1 GAM24056.1 - 0.015 15.1 0.2 0.023 14.5 0.1 1.5 1 1 0 1 1 1 0 DAHP synthase ferredoxin-like domain fn3 PF00041.21 GAM24057.1 - 0.071 13.5 0.2 0.47 10.8 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III domain EGF_2 PF07974.13 GAM24057.1 - 3.5 8.1 14.0 8.6 6.8 14.0 1.7 1 0 0 1 1 1 0 EGF-like domain Metallophos PF00149.28 GAM24058.1 - 5.5e-36 125.0 0.1 9.8e-36 124.2 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 GAM24058.1 - 0.0094 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5378) PPP5 PF08321.12 GAM24058.1 - 0.089 13.1 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 PPP5 TPR repeat region dCMP_cyt_deam_1 PF00383.23 GAM24059.1 - 4.1e-13 49.1 0.1 1.1e-12 47.7 0.1 1.8 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAM24059.1 - 8.8e-09 35.2 0.2 1.3e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 GAM24059.1 - 0.056 13.5 0.2 4 7.5 0.2 2.3 1 1 0 1 1 1 0 Bd3614-like deaminase Cys_rich_KTR PF14205.6 GAM24059.1 - 0.22 11.4 2.1 0.32 10.8 0.4 2.2 2 1 0 2 2 2 0 Cysteine-rich KTR PhnA_Zn_Ribbon PF08274.12 GAM24059.1 - 0.26 11.3 2.0 69 3.5 0.0 3.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon PAP_assoc PF03828.19 GAM24060.1 - 1.2e-07 31.8 0.4 3.4e-07 30.4 0.4 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAM24060.1 - 2.7e-07 30.8 0.0 7.3e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAM24060.1 - 0.0018 18.3 0.0 0.0047 17.0 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase TIM PF00121.18 GAM24061.1 - 8.4e-90 300.4 0.1 9.5e-90 300.2 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 GAM24061.1 - 0.033 13.6 0.0 2.3 7.7 0.0 2.1 1 1 1 2 2 2 0 CutC family ECH_1 PF00378.20 GAM24061.1 - 0.14 11.4 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF1084 PF06454.11 GAM24062.1 - 2.3e-09 37.1 19.5 4.6e-09 36.0 19.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) EGF_2 PF07974.13 GAM24062.1 - 1.3 9.4 15.7 0.17 12.3 11.6 1.7 2 0 0 2 2 2 0 EGF-like domain DUF1129 PF06570.11 GAM24062.1 - 3.9 6.9 11.6 0.039 13.4 3.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) HMG_CoA_synt_C PF08540.10 GAM24063.1 - 2e-86 290.1 0.5 3e-86 289.5 0.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 GAM24063.1 - 1.6e-85 285.3 0.2 2.5e-85 284.7 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Beta-lactamase PF00144.24 GAM24064.1 - 4.5e-59 200.3 0.0 6.8e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Methyltransf_25 PF13649.6 GAM24065.1 - 1.1e-18 67.7 0.0 2.3e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM24065.1 - 1.3e-18 67.2 0.0 2.3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 GAM24065.1 - 1.3e-17 64.2 0.0 3e-17 63.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM24065.1 - 1e-15 57.8 0.0 1.3e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM24065.1 - 3e-11 43.4 0.0 5.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM24065.1 - 2.2e-10 41.2 0.0 3.5e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAM24065.1 - 0.0026 17.6 0.0 0.0063 16.3 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 GAM24065.1 - 0.0043 17.1 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM24065.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TrkA_N PF02254.18 GAM24065.1 - 0.036 14.3 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain CMAS PF02353.20 GAM24065.1 - 0.069 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 GAM24065.1 - 0.16 11.4 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase ODAPH PF15848.5 GAM24065.1 - 0.18 12.2 0.1 9.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Odontogenesis associated phosphoprotein Phosphorylase PF00343.20 GAM24066.1 - 0 1048.6 0.1 0 1048.3 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase TAF6_C PF07571.13 GAM24067.1 - 1e-30 105.9 0.3 2.7e-30 104.6 0.1 1.9 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 GAM24067.1 - 3.8e-30 103.8 0.2 6.8e-30 103.0 0.2 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 GAM24067.1 - 0.0035 17.7 0.4 0.0066 16.8 0.4 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAM24067.1 - 0.014 15.7 0.7 0.03 14.6 0.1 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Serglycin PF04360.12 GAM24067.1 - 0.2 11.6 2.2 0.22 11.4 1.0 1.7 2 0 0 2 2 2 0 Serglycin Homeobox_KN PF05920.11 GAM24068.1 - 6.7e-09 35.5 1.1 1.2e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 GAM24068.1 - 1.8e-07 30.9 0.1 1.8e-07 30.9 0.1 2.8 3 0 0 3 3 3 1 Homeodomain DDE_Tnp_IS240 PF13610.6 GAM24068.1 - 0.0061 16.8 1.9 0.013 15.8 1.9 1.5 1 0 0 1 1 1 1 DDE domain Thioredoxin_11 PF18078.1 GAM24068.1 - 1.8 8.7 6.6 6.5 6.9 1.3 2.4 2 0 0 2 2 2 0 Thioredoxin-like SNTX domain 2Fe-2S_thioredx PF01257.19 GAM24069.1 - 9.6e-58 194.1 0.1 1.3e-57 193.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Osmo_CC PF08946.10 GAM24070.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.6 3 1 0 3 3 3 0 Osmosensory transporter coiled coil OrfB_IS605 PF01385.19 GAM24070.1 - 0.49 10.6 3.6 2.3 8.5 3.4 2.2 1 1 0 1 1 1 0 Probable transposase Carboxyl_trans PF01039.22 GAM24071.1 - 3.1e-192 639.6 0.1 3.6e-192 639.4 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain LSM PF01423.22 GAM24072.1 - 2.5e-06 27.1 0.1 3.2e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain Cytidylate_kin2 PF13189.6 GAM24074.1 - 0.0031 17.7 0.2 3.1 7.9 0.0 2.4 2 0 0 2 2 2 2 Cytidylate kinase-like family Cytidylate_kin PF02224.18 GAM24074.1 - 0.0042 16.8 1.2 0.18 11.5 0.1 2.4 2 1 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 GAM24074.1 - 0.013 15.9 1.4 0.019 15.4 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAM24074.1 - 0.071 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 GAM24074.1 - 0.08 13.5 0.3 0.19 12.3 0.1 2.0 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 GAM24074.1 - 0.15 11.9 0.5 5.4 6.8 0.1 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Ndc1_Nup PF09531.10 GAM24075.1 - 0.00047 19.0 0.6 0.00056 18.7 0.6 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup GLYCAM-1 PF05242.11 GAM24075.1 - 0.027 14.6 0.7 0.047 13.8 0.7 1.4 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) DUF1178 PF06676.11 GAM24075.1 - 0.095 13.1 2.3 0.16 12.4 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Polysacc_deac_1 PF01522.21 GAM24075.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase DUF2722 PF10846.8 GAM24075.1 - 0.12 11.3 7.5 0.17 10.8 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 GAM24075.1 - 0.31 11.0 11.8 0.43 10.5 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 GAM24075.1 - 3.1 7.3 17.0 5.2 6.6 17.0 1.3 1 0 0 1 1 1 0 Spt20 family YjbH PF06082.11 GAM24075.1 - 3.4 6.4 5.5 7.9 5.1 2.3 2.1 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH Hydrolase_4 PF12146.8 GAM24077.1 - 1.1e-66 224.5 0.3 1.9e-66 223.8 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM24077.1 - 3.4e-11 44.2 0.0 5.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAM24077.1 - 5.7e-11 42.6 0.6 5.6e-08 32.7 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 GAM24077.1 - 2.5e-05 24.1 0.2 0.00011 22.0 0.0 1.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 GAM24077.1 - 8.5e-05 22.1 0.8 0.017 14.6 0.0 3.3 4 0 0 4 4 4 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 GAM24077.1 - 0.00022 21.1 0.1 4.1 7.1 0.0 3.2 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase AXE1 PF05448.12 GAM24077.1 - 0.0014 17.4 0.0 0.018 13.7 0.0 2.4 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 GAM24077.1 - 0.0063 16.4 1.3 0.02 14.8 0.0 2.4 2 2 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 GAM24077.1 - 0.025 14.2 0.3 0.038 13.6 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Thioesterase PF00975.20 GAM24077.1 - 0.026 14.7 1.1 0.03 14.4 0.1 1.6 2 0 0 2 2 2 0 Thioesterase domain Asp_protease PF09668.10 GAM24079.1 - 1.5e-53 179.8 0.1 2.5e-53 179.1 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GAM24079.1 - 4.8e-19 68.7 0.0 1.1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 GAM24079.1 - 1.2e-10 41.0 0.9 3.7e-10 39.4 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin family Asp_protease_2 PF13650.6 GAM24079.1 - 1.2e-08 35.5 0.0 2.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease UBA_4 PF14555.6 GAM24079.1 - 0.0049 16.7 0.1 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain RVP PF00077.20 GAM24079.1 - 0.0086 16.4 0.0 0.03 14.6 0.0 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 GAM24079.1 - 0.043 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease CsiD PF08943.10 GAM24079.1 - 0.045 12.9 0.1 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 CsiD Ubiquitin_4 PF18036.1 GAM24079.1 - 0.045 13.8 0.1 0.27 11.3 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain DUF3347 PF11827.8 GAM24079.1 - 0.08 13.1 3.5 0.15 12.3 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) UBA PF00627.31 GAM24079.1 - 0.098 12.6 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 UBA/TS-N domain TBK1_ULD PF18396.1 GAM24079.1 - 0.56 10.2 7.5 0.78 9.7 1.1 3.1 3 0 0 3 3 3 0 TANK binding kinase 1 ubiquitin-like domain FNIP PF05725.12 GAM24080.1 - 2.8e-44 149.0 13.5 3.4e-15 55.9 0.4 5.1 2 1 2 6 6 6 5 FNIP Repeat DUF1769 PF08588.10 GAM24080.1 - 0.037 14.2 1.8 28 5.0 0.1 4.5 3 2 3 6 6 6 0 Protein of unknown function (DUF1769) TetR_C_5 PF08360.11 GAM24080.1 - 0.096 12.9 0.3 0.22 11.7 0.3 1.5 1 0 0 1 1 1 0 QacR-like protein, C-terminal region TIG PF01833.24 GAM24081.1 - 1e-41 140.9 137.8 9.4e-08 32.0 7.5 16.0 13 3 3 16 16 16 13 IPT/TIG domain Ank_2 PF12796.7 GAM24084.1 - 3.1e-07 30.9 0.1 0.0018 18.8 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM24084.1 - 2.1e-06 28.2 0.1 2.8 8.6 0.0 5.3 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM24084.1 - 0.0013 19.0 1.0 4.6 8.1 0.0 5.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 GAM24084.1 - 0.013 15.8 2.5 0.73 10.2 0.0 4.6 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM24086.1 - 5.7e-15 55.7 14.3 5.4e-05 23.7 0.3 4.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM24086.1 - 2.8e-12 46.9 15.1 0.0094 16.5 0.3 6.6 3 3 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM24086.1 - 6.5e-11 41.5 14.1 2.2 9.1 0.0 8.9 6 2 3 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 GAM24086.1 - 1.8e-09 37.6 13.0 0.18 12.1 0.1 7.8 5 3 4 9 9 9 4 Ankyrin repeats (many copies) DUF5049 PF16468.5 GAM24086.1 - 0.0014 18.4 1.2 11 6.0 0.0 4.8 4 1 1 5 5 5 1 Domain of unknown function (DUF5049) DUF3447 PF11929.8 GAM24086.1 - 0.0064 16.4 3.4 1.3 9.1 0.0 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Phage_TAC_2 PF06894.11 GAM24086.1 - 0.035 13.9 0.3 2.1 8.2 0.1 2.7 3 0 0 3 3 3 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G DUF4087 PF13316.6 GAM24086.1 - 0.048 14.2 0.0 4 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4087) Ank PF00023.30 GAM24086.1 - 0.35 11.4 9.5 12 6.6 0.1 5.5 6 2 0 6 6 6 0 Ankyrin repeat Ank_5 PF13857.6 GAM24087.1 - 0.00059 20.1 0.2 1.1 9.7 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM24087.1 - 0.013 15.9 0.1 0.77 10.5 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Noc2 PF03715.13 GAM24088.1 - 3.2e-101 338.5 3.6 3.2e-101 338.5 3.6 2.3 4 0 0 4 4 4 1 Noc2p family CDC27 PF09507.10 GAM24088.1 - 0.0069 15.8 11.4 0.0069 15.8 11.4 3.8 2 1 1 3 3 3 1 DNA polymerase subunit Cdc27 FAM176 PF14851.6 GAM24089.1 - 0.093 12.4 3.3 0.11 12.2 3.3 1.1 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 GAM24089.1 - 4 7.9 11.0 0.86 10.0 8.0 1.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Metallophos PF00149.28 GAM24090.1 - 1.9e-09 38.3 0.1 1.8e-08 35.2 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM24090.1 - 6.4e-05 23.2 0.0 0.00018 21.7 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3487 PF11990.8 GAM24090.1 - 0.011 15.6 0.3 0.011 15.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) PIG-P PF08510.12 GAM24090.1 - 0.95 9.4 9.3 4.8 7.1 6.4 2.7 2 0 0 2 2 2 0 PIG-P DUF5504 PF17608.2 GAM24090.1 - 4.2 7.5 8.0 21 5.2 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5504) Syntaxin-6_N PF09177.11 GAM24091.1 - 2.2e-23 82.7 1.9 7e-23 81.1 0.2 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal Use1 PF09753.9 GAM24091.1 - 1.5e-05 24.9 4.3 3.1e-05 23.8 3.8 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 GAM24091.1 - 2.7e-05 24.1 1.4 2.7e-05 24.1 1.4 1.8 2 0 0 2 2 2 1 SNARE domain CHDCT2 PF08074.11 GAM24091.1 - 0.01 16.0 0.9 1.4 9.0 0.2 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Phage_holin_2_1 PF04971.12 GAM24091.1 - 0.031 14.3 0.1 0.06 13.3 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF16 PF01519.16 GAM24091.1 - 0.04 14.4 3.1 0.48 10.9 3.1 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 EMP24_GP25L PF01105.24 GAM24091.1 - 0.054 13.4 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD XhlA PF10779.9 GAM24091.1 - 0.11 12.8 1.3 0.89 9.8 0.1 2.7 2 1 0 2 2 2 0 Haemolysin XhlA CorA PF01544.18 GAM24091.1 - 1.8 7.8 5.2 3.8 6.7 1.7 2.4 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein adh_short PF00106.25 GAM24092.1 - 3.9e-39 134.1 0.0 5.1e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM24092.1 - 1.4e-22 80.4 0.0 1.8e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM24092.1 - 8.5e-10 38.8 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM24092.1 - 0.0043 16.2 0.2 0.0058 15.8 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 GAM24092.1 - 0.021 14.7 0.6 0.032 14.1 0.6 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 GAM24092.1 - 0.097 12.1 0.2 0.18 11.2 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 GAM24092.1 - 0.16 12.7 0.1 0.3 11.8 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain SSrecog PF03531.14 GAM24092.1 - 0.18 11.7 0.1 0.63 10.0 0.0 1.9 2 0 0 2 2 2 0 Structure-specific recognition protein (SSRP1) adh_short PF00106.25 GAM24093.1 - 1.5e-39 135.5 0.1 2e-39 135.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM24093.1 - 5.3e-23 81.8 0.2 7.4e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM24093.1 - 7.4e-11 42.3 0.1 1.1e-10 41.7 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF218 PF02698.17 GAM24093.1 - 0.035 14.1 0.5 0.07 13.2 0.3 1.7 1 1 0 1 1 1 0 DUF218 domain Mo25 PF08569.11 GAM24094.1 - 6.8e-133 443.1 14.4 7.7e-133 442.9 14.4 1.0 1 0 0 1 1 1 1 Mo25-like HMA PF00403.26 GAM24095.1 - 3.4e-12 46.6 1.6 4e-12 46.4 1.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 GAM24095.1 - 0.015 15.7 0.1 0.091 13.1 0.0 1.9 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Cullin_binding PF03556.15 GAM24096.1 - 1.9e-29 102.5 1.0 2.7e-29 102.0 1.0 1.2 1 0 0 1 1 1 1 Cullin binding Macoilin PF09726.9 GAM24096.1 - 0.03 12.9 5.6 0.032 12.8 5.6 1.2 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 GAM24096.1 - 0.13 10.9 3.9 0.15 10.8 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 GAM24096.1 - 0.19 10.5 6.7 0.2 10.4 6.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain MSP1_C PF07462.11 GAM24096.1 - 0.74 8.4 5.9 1.3 7.7 5.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Presenilin PF01080.17 GAM24096.1 - 1.6 7.4 4.2 1.8 7.2 4.2 1.1 1 0 0 1 1 1 0 Presenilin GET2 PF08690.10 GAM24096.1 - 4.4 6.9 10.5 8.4 6.0 10.5 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Nucleotid_trans PF03407.16 GAM24097.1 - 0.004 17.2 0.1 0.0074 16.3 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_8 PF01501.20 GAM24097.1 - 0.0082 15.7 1.5 0.025 14.1 1.5 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 DUF1462 PF07315.11 GAM24097.1 - 0.039 14.2 0.3 0.75 10.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1462) YorP PF09629.10 GAM24097.1 - 0.55 10.5 2.8 8.2 6.7 0.1 2.7 3 0 0 3 3 3 0 YorP protein UCH PF00443.29 GAM24098.1 - 6.1e-67 225.8 0.0 1.6e-65 221.1 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAM24098.1 - 5.8e-19 68.5 0.0 5.8e-19 68.5 0.0 3.5 5 0 0 5 5 5 1 DUSP domain zf_UBZ PF18439.1 GAM24098.1 - 4.2 7.1 9.4 0.26 10.9 0.2 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Sec3_C PF09763.9 GAM24098.1 - 5.5 5.2 14.8 0.24 9.8 3.2 2.6 2 0 0 2 2 2 0 Exocyst complex component Sec3 Abhydrolase_1 PF00561.20 GAM24099.1 - 5e-18 65.7 0.7 1.7e-17 63.9 0.6 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM24099.1 - 3.9e-14 52.5 0.0 6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM24099.1 - 2.2e-13 51.4 0.0 2.9e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 GAM24099.1 - 0.0045 16.1 0.0 0.0087 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.20 GAM24099.1 - 0.018 14.7 0.2 0.11 12.1 0.1 2.2 2 1 0 2 2 2 0 Putative esterase SapB_1 PF05184.15 GAM24100.1 - 0.00076 19.5 0.5 0.00076 19.5 0.5 2.0 2 0 0 2 2 2 1 Saposin-like type B, region 1 Prok-RING_4 PF14447.6 GAM24100.1 - 0.0078 16.1 1.0 0.12 12.3 0.2 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Linocin_M18 PF04454.12 GAM24100.1 - 0.042 13.1 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase SapB_2 PF03489.17 GAM24100.1 - 0.14 12.3 15.4 0.5 10.5 0.0 5.1 4 1 0 4 4 4 0 Saposin-like type B, region 2 zf-ANAPC11 PF12861.7 GAM24100.1 - 0.77 9.8 5.4 5.7 7.1 0.0 3.0 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger GST_N_4 PF17172.4 GAM24101.1 - 3.1e-19 69.5 0.0 6.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GAM24101.1 - 1.8e-15 56.5 0.0 3.7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM24101.1 - 2.4e-09 37.1 0.1 4.2e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 GAM24101.1 - 3.8e-08 33.7 0.0 7.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 GAM24101.1 - 3.1e-06 27.5 0.0 1.7e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM24101.1 - 0.00018 21.6 0.0 0.00029 21.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM24101.1 - 0.00036 20.7 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4119 PF13494.6 GAM24101.1 - 0.0033 17.5 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF4119) GST_C_5 PF16865.5 GAM24101.1 - 0.11 13.1 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM24101.1 - 0.13 12.6 0.1 1.3 9.3 0.1 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TIG PF01833.24 GAM24102.1 - 1.1e-05 25.4 6.1 1.1e-05 25.4 6.1 4.7 4 0 0 4 4 4 1 IPT/TIG domain Qn_am_d_aIII PF09099.10 GAM24102.1 - 0.47 10.9 22.9 7.9 6.9 0.2 7.8 6 2 0 6 6 6 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Sec7 PF01369.20 GAM24103.1 - 1.6e-61 207.2 0.2 3e-61 206.3 0.2 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 GAM24103.1 - 2e-10 41.1 10.0 1.9e-08 34.8 0.8 3.4 4 0 0 4 4 4 2 PH domain PH_11 PF15413.6 GAM24103.1 - 0.0032 17.9 6.8 0.037 14.5 0.2 2.8 3 0 0 3 3 3 2 Pleckstrin homology domain Calreticulin PF00262.18 GAM24104.1 - 6.4e-81 272.0 15.1 3.9e-59 200.4 4.6 2.6 2 1 1 3 3 3 2 Calreticulin family MDM10 PF12519.8 GAM24104.1 - 1.9 7.3 4.5 3 6.6 4.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 RPN7 PF10602.9 GAM24105.1 - 5.3e-46 156.5 1.1 5.9e-37 127.0 1.1 2.6 1 1 1 2 2 2 2 26S proteasome subunit RPN7 PCI PF01399.27 GAM24105.1 - 1.5e-17 64.0 2.6 1.5e-17 64.0 0.8 2.0 2 0 0 2 2 2 1 PCI domain TPR_1 PF00515.28 GAM24105.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat GCH_III PF05165.12 GAM24105.1 - 0.015 14.6 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase III NRBF2 PF08961.10 GAM24105.1 - 0.025 14.2 0.4 0.051 13.2 0.0 1.6 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator TPR_7 PF13176.6 GAM24105.1 - 0.025 14.6 0.0 0.082 13.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM24105.1 - 0.12 12.5 0.0 0.4 10.9 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribonuc_red_lgC PF02867.15 GAM24106.1 - 8.2e-185 615.3 0.0 1.1e-184 614.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAM24106.1 - 7.4e-21 73.9 0.0 1.7e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAM24106.1 - 6.5e-15 55.5 0.0 1.5e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain RabGAP-TBC PF00566.18 GAM24107.1 - 2.1e-27 96.2 8.6 2.8e-25 89.2 8.6 3.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TRAP_beta PF05753.14 GAM24108.1 - 2.4e-38 131.3 0.2 3e-38 131.0 0.2 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) Smg8_Smg9 PF10220.9 GAM24109.1 - 8.9e-60 203.0 14.5 2.2e-36 125.6 2.0 4.0 3 1 1 4 4 4 3 Smg8_Smg9 Ndc1_Nup PF09531.10 GAM24109.1 - 0.0022 16.8 6.7 0.0033 16.2 6.7 1.3 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 GAM24109.1 - 0.0029 17.7 17.7 0.0061 16.6 17.7 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 GAM24109.1 - 0.097 11.2 11.2 0.16 10.5 11.2 1.3 1 0 0 1 1 1 0 Macoilin family PYRIN PF02758.16 GAM24109.1 - 0.36 11.0 0.0 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain SOG2 PF10428.9 GAM24109.1 - 0.61 9.2 24.1 0.97 8.6 24.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 GAM24109.1 - 0.92 8.2 13.9 1.9 7.1 13.9 1.5 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 GAM24109.1 - 4.1 5.7 12.3 6.1 5.1 12.3 1.1 1 0 0 1 1 1 0 Menin Suf PF05843.14 GAM24109.1 - 5.9 6.8 13.8 14 5.6 13.8 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Dicty_REP PF05086.12 GAM24110.1 - 0.00053 18.1 9.5 0.00053 18.1 9.5 4.5 3 1 0 4 4 4 1 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.25 GAM24111.1 - 6.9e-67 225.6 0.0 1e-66 225.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24111.1 - 1.5e-51 175.1 0.0 2.8e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM24111.1 - 1.5e-06 27.2 0.2 3.3e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Mst1_SARAH PF11629.8 GAM24111.1 - 0.028 14.5 0.6 0.066 13.3 0.6 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 RFXA_RFXANK_bdg PF15289.6 GAM24111.1 - 8.5 6.7 7.6 1.9 8.8 4.1 1.7 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain RasGAP PF00616.19 GAM24112.1 - 1.9e-30 106.1 9.6 4.3e-23 82.1 0.1 3.8 2 2 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase MAD PF05557.13 GAM24112.1 - 0.0016 16.9 10.3 0.0016 16.9 10.3 1.5 2 0 0 2 2 2 1 Mitotic checkpoint protein DUF2884 PF11101.8 GAM24112.1 - 0.075 12.5 4.1 1.2 8.6 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) XLF PF09302.11 GAM24112.1 - 0.15 12.2 7.2 0.054 13.7 2.8 2.4 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component HAUS5 PF14817.6 GAM24112.1 - 0.29 9.9 11.4 0.37 9.5 10.0 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 YlqD PF11068.8 GAM24112.1 - 1.9 8.9 12.3 0.55 10.6 7.0 2.6 2 0 0 2 2 2 0 YlqD protein AAA_23 PF13476.6 GAM24112.1 - 8 6.9 23.6 47 4.4 20.7 3.1 2 1 0 2 2 2 0 AAA domain Arf PF00025.21 GAM24113.1 - 2e-45 154.4 0.0 2.4e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAM24113.1 - 5.5e-20 71.6 0.0 6.8e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24113.1 - 8e-17 61.6 0.0 1.1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAM24113.1 - 1.9e-10 40.5 0.1 2.6e-07 30.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAM24113.1 - 2.1e-10 40.3 0.0 3.2e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM24113.1 - 3.8e-09 36.6 0.0 5.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAM24113.1 - 1.4e-07 31.1 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 GAM24113.1 - 0.03 13.8 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 GAM24113.1 - 0.049 13.2 0.7 0.076 12.5 0.3 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 GAM24113.1 - 0.083 12.9 0.1 1.5 8.9 0.1 2.1 1 1 1 2 2 2 0 Dynamin family VPS9 PF02204.18 GAM24114.1 - 1.2e-19 70.4 0.2 1.6e-18 66.9 0.2 2.7 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 GAM24114.1 - 5.5e-19 68.2 3.4 7.6e-19 67.8 1.1 2.4 2 0 0 2 2 2 1 PX domain Ras PF00071.22 GAM24114.1 - 1.3e-09 37.9 0.0 2.5e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Ras family DUF5601 PF18151.1 GAM24114.1 - 0.0031 17.8 3.3 0.004 17.4 0.4 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF5601) DMA PF03474.14 GAM24114.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif CUE PF02845.16 GAM24114.1 - 0.039 13.7 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 CUE domain Roc PF08477.13 GAM24114.1 - 0.078 13.2 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FNIP PF05725.12 GAM24115.1 - 2.6e-82 270.8 42.5 2.6e-12 46.7 0.2 10.7 6 2 2 10 10 10 10 FNIP Repeat Pro-rich_19 PF15455.6 GAM24115.1 - 0.12 11.5 0.2 0.18 10.9 0.2 1.2 1 0 0 1 1 1 0 Proline-rich 19 Pro_isomerase PF00160.21 GAM24116.1 - 6.1e-41 140.3 0.0 6.1e-41 140.3 0.0 2.1 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Dicty_REP PF05086.12 GAM24116.1 - 0.034 12.1 20.8 0.046 11.7 20.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mitofilin PF09731.9 GAM24116.1 - 0.066 12.1 21.2 0.087 11.7 21.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.9 GAM24116.1 - 0.6 8.6 15.0 0.74 8.3 15.0 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_C1 PF00112.23 GAM24117.1 - 5.1e-42 144.4 1.9 7.4e-42 143.9 1.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 GAM24117.1 - 0.0044 17.8 0.8 0.043 14.7 0.0 2.6 3 0 0 3 3 3 1 Cysteine-rich secretory protein family Response_reg PF00072.24 GAM24118.1 - 2.8e-20 72.6 0.1 3e-20 72.5 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.6 GAM24119.1 - 3.3e-34 118.7 0.0 1.3e-33 116.8 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain HATPase_c PF02518.26 GAM24119.1 - 2.1e-28 99.0 0.3 6.7e-28 97.4 0.3 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 GAM24119.1 - 1.2e-20 74.0 0.0 3e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain HisKA PF00512.25 GAM24119.1 - 8.4e-17 61.0 0.2 2.9e-16 59.3 0.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pkinase_Tyr PF07714.17 GAM24119.1 - 1.8e-14 53.7 0.0 1e-13 51.2 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase GAF PF01590.26 GAM24119.1 - 1.3e-09 38.8 0.0 5.6e-09 36.7 0.0 2.2 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.6 GAM24119.1 - 1.4e-06 28.6 0.0 3.1e-05 24.3 0.0 2.6 2 0 0 2 2 2 1 GAF domain AAA_22 PF13401.6 GAM24119.1 - 0.00051 20.3 0.0 0.0045 17.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain GAF_3 PF13492.6 GAM24119.1 - 0.0083 16.5 0.0 0.026 14.8 0.0 2.0 2 0 0 2 2 1 1 GAF domain DUF815 PF05673.13 GAM24119.1 - 0.038 13.2 0.4 2.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 GAM24119.1 - 0.061 13.2 0.1 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 GAM24119.1 - 0.085 12.8 0.2 2.4 8.0 0.1 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 GAM24119.1 - 0.099 13.2 0.2 0.41 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAM24119.1 - 0.14 12.6 0.1 1.1 9.7 0.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HATPase_c_3 PF13589.6 GAM24119.1 - 0.16 11.8 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zeta_toxin PF06414.12 GAM24119.1 - 0.16 11.3 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PUA PF01472.20 GAM24120.1 - 1.1e-07 31.7 0.1 1.2e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 GAM24121.1 - 1.5e-26 92.9 0.3 1.8e-26 92.6 0.3 1.0 1 0 0 1 1 1 1 Pre-PUA-like domain DUF1947 PF09183.10 GAM24121.1 - 0.011 16.0 0.7 0.065 13.5 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1947) LRR_4 PF12799.7 GAM24122.1 - 3.9 8.0 8.3 15 6.2 1.3 4.8 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) Peptidase_C1 PF00112.23 GAM24123.1 - 8.6e-50 169.8 5.0 1.7e-49 168.9 5.0 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 GAM24123.1 - 3.2e-05 22.9 0.4 0.0048 15.7 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family CAP PF00188.26 GAM24123.1 - 1.9 9.4 9.4 0.23 12.3 4.2 2.1 2 1 0 2 2 2 0 Cysteine-rich secretory protein family Inhibitor_I29 PF08246.12 GAM24124.1 - 4.7e-13 49.3 2.1 1.1e-12 48.2 2.1 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) RhoGAP PF00620.27 GAM24125.1 - 1.9e-33 115.5 0.1 1.9e-33 115.5 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain BAR_3 PF16746.5 GAM24125.1 - 2.8e-06 27.2 1.2 2.8e-06 27.2 1.2 2.2 2 0 0 2 2 2 1 BAR domain of APPL family RED_N PF07808.13 GAM24125.1 - 3.4 7.2 11.3 3.6 7.1 7.4 2.4 2 0 0 2 2 2 0 RED-like protein N-terminal region BAR PF03114.18 GAM24126.1 - 3.2e-06 27.0 0.4 4.1e-06 26.6 0.4 1.1 1 0 0 1 1 1 1 BAR domain Hemocyanin_C PF03723.14 GAM24126.1 - 0.038 13.3 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Hemocyanin, ig-like domain TMP-TENI PF02581.17 GAM24126.1 - 0.13 11.6 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Thiamine monophosphate synthase p450 PF00067.22 GAM24127.1 - 1.9e-75 254.4 0.0 2.3e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VIT PF08487.10 GAM24128.1 - 1.7e-31 108.7 0.7 4.5e-31 107.4 0.7 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 GAM24128.1 - 1.2e-28 100.0 0.0 7e-28 97.5 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 GAM24128.1 - 5.6e-12 46.3 1.1 3.2e-11 43.8 0.0 2.6 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM24128.1 - 8e-10 39.3 0.0 4.6e-09 36.9 0.0 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain VIT_2 PF13757.6 GAM24128.1 - 0.00043 20.1 0.1 0.0018 18.1 0.1 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.9 GAM24128.1 - 0.0023 18.1 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF1828 PF08861.10 GAM24128.1 - 0.027 14.7 0.1 7 7.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF1828 VWA_CoxE PF05762.14 GAM24128.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Phage_Mu_Gam PF07352.12 GAM24128.1 - 1.9 8.4 5.9 14 5.6 0.2 3.0 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein FNIP PF05725.12 GAM24129.1 - 1.1e-16 60.7 11.9 4.6e-06 26.7 0.0 6.0 4 2 1 6 6 6 4 FNIP Repeat EHD_N PF16880.5 GAM24129.1 - 0.031 14.2 0.4 0.072 13.0 0.4 1.6 1 0 0 1 1 1 0 N-terminal EH-domain containing protein GFA PF04828.14 GAM24131.1 - 1e-05 25.8 1.8 1e-05 25.8 1.8 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ank_5 PF13857.6 GAM24132.1 - 1.7e-17 63.2 2.1 6.4e-09 35.9 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAM24132.1 - 1.1e-13 50.9 0.1 4.5e-07 30.0 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 GAM24132.1 - 8.8e-13 48.5 0.2 1.3e-05 25.7 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM24132.1 - 1.7e-11 44.5 0.0 4.8e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM24132.1 - 1.7e-10 40.2 0.3 0.00052 20.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat RA PF00788.23 GAM24132.1 - 1.6e-07 31.8 0.0 2.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pet191_N PF10203.9 GAM24133.1 - 0.031 14.6 6.0 2 8.8 0.1 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Pribosyltran_N PF13793.6 GAM24134.1 - 2.1e-43 146.9 0.6 2.9e-42 143.3 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAM24134.1 - 5.2e-33 114.6 8.7 6.4e-31 107.8 2.7 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAM24134.1 - 1.4e-11 44.1 1.8 2.1e-11 43.6 0.3 2.0 3 0 0 3 3 3 1 Phosphoribosyl transferase domain L51_S25_CI-B8 PF05047.16 GAM24135.1 - 1.1e-10 41.2 0.1 1.6e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Lipase_GDSL_3 PF14606.6 GAM24135.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Epimerase PF01370.21 GAM24136.1 - 3.1e-20 72.7 0.2 4.6e-20 72.1 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM24136.1 - 1.8e-17 63.4 0.2 2.4e-16 59.7 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 GAM24136.1 - 4.2e-17 62.1 0.0 5.6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM24136.1 - 7.2e-12 45.4 0.3 1.1e-11 44.7 0.1 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAM24136.1 - 8e-12 45.4 0.5 3.1e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 GAM24136.1 - 8.2e-07 28.8 0.5 1.3e-06 28.2 0.5 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 GAM24136.1 - 7.5e-05 22.0 0.8 0.00012 21.4 0.2 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 GAM24136.1 - 0.00044 20.2 0.2 0.0018 18.2 0.2 2.0 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 GAM24136.1 - 0.00092 18.4 0.3 0.0017 17.5 0.3 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 GAM24136.1 - 0.011 16.0 0.3 0.043 14.1 0.2 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 GAM24136.1 - 0.02 15.3 0.2 0.047 14.1 0.2 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAM24136.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus EZH2_N PF18601.1 GAM24136.1 - 0.14 12.5 0.3 0.33 11.3 0.3 1.6 1 0 0 1 1 1 0 EZH2 N-terminal domain IncD PF17628.2 GAM24137.1 - 0.26 11.1 2.8 0.74 9.6 0.3 2.0 1 1 1 2 2 2 0 Inclusion membrane protein D TMEM213 PF15192.6 GAM24137.1 - 6 6.9 17.1 0.56 10.2 1.5 3.0 1 1 2 3 3 3 0 TMEM213 family PLDc PF00614.22 GAM24143.1 - 0.11 12.7 0.4 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Phospholipase D Active site motif Cdh1_DBD_1 PF18196.1 GAM24144.1 - 0.023 15.0 0.2 0.075 13.3 0.2 1.8 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 zf-CDGSH PF09360.10 GAM24145.1 - 1.3e-12 47.8 6.4 4e-08 33.4 1.4 3.3 3 2 0 3 3 3 2 Iron-binding zinc finger CDGSH type Phage_H_T_join PF05521.11 GAM24145.1 - 0.028 14.9 0.3 0.042 14.4 0.3 1.3 1 0 0 1 1 1 0 Phage head-tail joining protein Tub_N PF16322.5 GAM24145.1 - 0.2 12.1 5.5 0.25 11.7 5.5 1.1 1 0 0 1 1 1 0 Tubby N-terminal Myc_N PF01056.18 GAM24145.1 - 7 6.4 8.9 8.8 6.1 8.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region UDG PF03167.19 GAM24146.1 - 7.6e-25 87.7 0.0 1.3e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Dicty_REP PF05086.12 GAM24146.1 - 0.0015 16.7 12.1 0.0018 16.4 12.1 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein SDA1 PF05285.12 GAM24146.1 - 2.3 7.5 19.2 3.3 7.1 19.2 1.2 1 0 0 1 1 1 0 SDA1 PAF PF15715.5 GAM24146.1 - 3 8.5 17.6 6.6 7.3 17.6 1.6 1 1 0 1 1 1 0 PCNA-associated factor histone like domain ORC6 PF05460.13 GAM24146.1 - 3.3 6.9 9.9 4.8 6.3 9.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RhoGEF PF00621.20 GAM24147.1 - 1.6e-45 155.6 1.3 1.6e-45 155.6 1.3 2.0 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 GAM24147.1 - 2.1e-16 59.8 10.5 4.7e-16 58.7 10.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 GAM24147.1 - 2.4e-11 44.1 0.2 7.1e-11 42.5 0.2 1.8 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 GAM24147.1 - 0.00026 21.0 1.9 0.0003 20.8 0.1 2.0 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 GAM24147.1 - 0.00028 20.7 3.0 0.00028 20.7 3.0 3.0 3 1 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 GAM24147.1 - 0.0043 17.1 0.9 0.01 15.9 0.1 2.1 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 GAM24147.1 - 0.072 12.9 0.0 0.28 11.0 0.0 2.0 1 1 0 1 1 1 0 PH domain Na_Ca_ex PF01699.24 GAM24148.1 - 1.3e-14 54.4 31.9 2.7e-10 40.4 14.8 2.4 2 1 0 2 2 2 2 Sodium/calcium exchanger protein YukC PF10140.9 GAM24148.1 - 0.098 11.5 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF4956 PF16316.5 GAM24148.1 - 1 9.0 5.9 0.83 9.3 3.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) FNIP PF05725.12 GAM24149.1 - 2.6e-58 194.0 20.7 8.3e-11 41.9 0.0 9.7 7 1 2 10 10 10 8 FNIP Repeat FAM177 PF14774.6 GAM24150.1 - 3.3e-15 56.5 0.9 4.8e-15 56.0 0.9 1.3 1 0 0 1 1 1 1 FAM177 family Spt20 PF12090.8 GAM24150.1 - 0.0016 18.1 8.7 0.0018 18.0 8.7 1.1 1 0 0 1 1 1 1 Spt20 family Protamine_P2 PF00841.19 GAM24150.1 - 0.04 14.4 1.8 0.04 14.4 1.8 2.1 2 0 0 2 2 2 0 Sperm histone P2 CDK2AP PF09806.9 GAM24150.1 - 2.8 7.9 10.9 6.9 6.7 4.0 2.0 1 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Androgen_recep PF02166.16 GAM24150.1 - 9.4 5.0 14.8 2.5 6.8 12.1 1.4 2 0 0 2 2 2 0 Androgen receptor RNA_pol PF00940.19 GAM24151.1 - 1.4e-168 561.0 0.0 4.4e-168 559.4 0.0 1.8 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 GAM24151.1 - 1.2e-41 143.3 0.0 1.9e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal CRIM PF16978.5 GAM24152.1 - 5.2e-05 23.4 0.0 0.0018 18.4 0.0 2.4 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 GAM24152.1 - 0.0023 18.2 1.3 0.0096 16.2 1.3 2.1 1 1 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology ubiquitin PF00240.23 GAM24152.1 - 0.036 13.8 0.2 5.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin family DPBB_1 PF03330.18 GAM24153.1 - 2.4e-10 40.5 0.4 4.8e-09 36.4 0.4 2.3 1 1 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 GAM24153.1 - 0.006 16.7 0.4 0.012 15.7 0.4 1.5 1 0 0 1 1 1 1 Cerato-platanin Aspzincin_M35 PF14521.6 GAM24153.1 - 0.1 13.2 0.2 0.15 12.6 0.2 1.2 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Ribosomal_L1 PF00687.21 GAM24154.1 - 6e-30 104.5 1.4 2e-29 102.8 1.4 1.9 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family G10 PF01125.17 GAM24155.1 - 3.9e-05 23.4 37.4 0.00062 19.5 18.8 2.4 2 0 0 2 2 2 2 G10 protein cobW PF02492.19 GAM24156.1 - 1.3e-08 34.7 2.5 0.0012 18.5 0.3 2.6 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 GAM24156.1 - 0.01 15.4 0.1 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAM24156.1 - 0.011 16.2 0.0 0.038 14.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 GAM24156.1 - 0.028 14.3 0.1 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 GAM24156.1 - 0.076 13.0 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAM24156.1 - 0.11 12.5 0.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase CobW_C PF07683.14 GAM24156.1 - 0.15 12.0 0.0 0.5 10.3 0.0 1.9 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain AAA_28 PF13521.6 GAM24156.1 - 0.19 11.9 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gcd10p PF04189.13 GAM24157.1 - 2.7e-55 187.6 0.1 2.7e-55 187.6 0.1 2.5 3 0 0 3 3 3 1 Gcd10p family Ribosomal_S8 PF00410.19 GAM24157.1 - 2.6 8.0 6.2 0.36 10.8 1.1 2.3 2 1 0 2 2 2 0 Ribosomal protein S8 DUF2577 PF10844.8 GAM24157.1 - 9.2 6.6 13.4 0.55 10.5 4.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2577) Ku_N PF03731.15 GAM24158.1 - 8.4e-27 94.3 0.1 1.1e-26 93.9 0.1 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 GAM24159.1 - 1e-54 185.4 0.0 2.2e-54 184.3 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 GAM24159.1 - 1.4e-14 54.4 5.0 1.4e-14 54.4 5.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 GAM24159.1 - 1.9e-12 47.7 1.0 1.9e-12 47.7 1.0 3.1 2 1 0 2 2 2 1 Ku70/Ku80 C-terminal arm zf-CCHH PF10283.9 GAM24159.1 - 4.8e-09 36.0 4.1 7.8e-09 35.4 4.1 1.4 1 0 0 1 1 1 1 PBZ domain HeH PF12949.7 GAM24159.1 - 0.04 13.6 0.2 0.1 12.4 0.2 1.7 1 0 0 1 1 1 0 HeH/LEM domain DUF4518 PF15008.6 GAM24159.1 - 0.14 11.3 2.7 0.39 9.9 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) Mucin PF01456.17 GAM24159.1 - 3.9 7.5 22.0 0.43 10.6 16.9 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Dynamin_N PF00350.23 GAM24162.1 - 2.2e-21 76.7 2.8 4e-20 72.6 0.0 2.6 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAM24162.1 - 1.2e-05 25.3 0.0 5.3e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 GAM24162.1 - 0.082 12.5 0.2 9 5.9 0.0 2.7 1 1 1 2 2 2 0 Ras family ABC_tran PF00005.27 GAM24162.1 - 0.13 12.8 4.3 0.18 12.3 0.0 3.1 3 0 0 3 3 3 0 ABC transporter AAA_16 PF13191.6 GAM24162.1 - 0.41 11.0 4.7 0.89 9.9 0.0 3.5 3 1 1 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 GAM24162.1 - 5.9 7.3 0.0 5.9 7.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain SNARE_assoc PF09335.11 GAM24164.1 - 4.9e-30 104.5 4.7 4.9e-30 104.5 4.7 1.9 2 1 1 3 3 3 1 SNARE associated Golgi protein TMEM154 PF15102.6 GAM24164.1 - 0.00091 19.2 0.3 0.0017 18.3 0.3 1.4 1 0 0 1 1 1 1 TMEM154 protein family Hexapep_loop PF18776.1 GAM24164.1 - 0.068 12.8 0.5 0.16 11.6 0.5 1.6 1 0 0 1 1 1 0 Hexapeptide repeat including loop DUF2976 PF11190.8 GAM24164.1 - 0.28 11.0 5.8 3.7 7.4 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF1772 PF08592.11 GAM24164.1 - 0.29 11.4 4.3 2.7 8.3 4.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF1129 PF06570.11 GAM24164.1 - 0.49 9.9 8.3 0.31 10.5 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) RseC_MucC PF04246.12 GAM24164.1 - 8.9 6.3 6.0 7.8 6.5 0.3 2.4 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC TIG PF01833.24 GAM24165.1 - 9.4e-06 25.6 6.5 0.00018 21.5 1.0 2.7 2 0 0 2 2 2 2 IPT/TIG domain Lectin_C PF00059.21 GAM24165.1 - 1.8e-05 25.4 0.4 5.8e-05 23.8 0.2 2.0 2 1 0 2 2 2 1 Lectin C-type domain TIG PF01833.24 GAM24166.1 - 1.4e-10 41.1 19.3 2.3e-07 30.8 6.9 3.4 3 1 1 4 4 4 2 IPT/TIG domain DUF2093 PF09866.9 GAM24166.1 - 0.014 14.9 0.6 0.026 13.9 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) EGF_2 PF07974.13 GAM24166.1 - 0.024 15.0 7.7 0.053 13.9 7.7 1.6 1 0 0 1 1 1 0 EGF-like domain I-EGF_1 PF18372.1 GAM24166.1 - 0.028 14.5 6.3 0.068 13.3 6.3 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EB PF01683.18 GAM24166.1 - 0.05 13.9 4.4 0.1 12.9 4.4 1.6 1 0 0 1 1 1 0 EB module hEGF PF12661.7 GAM24166.1 - 0.58 10.9 3.9 1.7 9.4 3.9 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 GAM24166.1 - 0.58 10.3 9.5 0.84 9.8 5.2 2.6 2 0 0 2 2 2 0 Tenascin EGF domain Coiled PF05710.12 GAM24168.1 - 8.5e-06 26.5 11.1 1.1e-05 26.1 11.1 1.2 1 0 0 1 1 1 1 Coiled coil UPF0126 PF03458.13 GAM24168.1 - 0.71 9.8 7.0 1 9.3 5.9 1.7 1 1 1 2 2 2 0 UPF0126 domain TPR_1 PF00515.28 GAM24169.1 - 1.7e-21 75.1 4.3 0.00045 19.9 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAM24169.1 - 8e-19 66.2 8.2 7e-05 22.6 0.0 6.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM24169.1 - 1.9e-18 65.8 8.4 0.00063 19.4 0.3 6.5 3 3 3 6 6 6 4 TPR repeat TPR_17 PF13431.6 GAM24169.1 - 1e-15 56.9 16.2 3.5e-05 23.9 0.5 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAM24169.1 - 4.1e-15 55.2 4.0 0.0013 19.4 0.1 6.3 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAM24169.1 - 2.2e-14 53.8 1.3 2.2e-05 25.0 0.2 4.5 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM24169.1 - 1.4e-12 47.9 13.8 0.00048 20.6 0.6 5.2 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_20 PF14561.6 GAM24169.1 - 2.2e-12 47.1 6.8 0.0039 17.5 0.2 5.5 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAM24169.1 - 8.3e-10 38.1 9.5 0.011 15.9 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM24169.1 - 1.9e-09 36.8 4.4 1.9 8.7 0.0 5.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAM24169.1 - 8.3e-07 29.1 0.2 0.018 15.2 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM24169.1 - 9.7e-07 28.9 2.4 0.008 16.4 0.0 3.4 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAM24169.1 - 1.4e-06 28.5 7.6 0.0047 17.2 1.1 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM24169.1 - 5.4e-05 23.6 4.2 6.7 7.6 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat ChAPs PF09295.10 GAM24169.1 - 0.0013 17.8 0.7 0.087 11.8 0.0 2.2 1 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 GAM24169.1 - 0.006 16.4 11.3 7.8 6.5 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAM24169.1 - 0.0064 15.7 2.3 0.56 9.4 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 GAM24169.1 - 0.0094 16.4 1.4 0.44 11.0 0.1 3.2 3 0 0 3 3 3 1 Bacterial transcriptional activator domain DUF4248 PF14053.6 GAM24169.1 - 0.0098 15.9 0.5 0.21 11.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4248) NARP1 PF12569.8 GAM24169.1 - 0.038 12.9 2.0 0.16 10.9 0.2 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 MIT PF04212.18 GAM24169.1 - 0.04 14.0 5.0 43 4.3 0.0 5.4 6 1 1 7 7 5 0 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.14 GAM24169.1 - 0.05 13.0 0.4 0.56 9.6 0.1 2.3 2 0 0 2 2 2 0 Coatomer epsilon subunit DUF4082 PF13313.6 GAM24169.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) FNIP PF05725.12 GAM24170.1 - 3.3e-33 113.6 6.1 2.8e-13 49.8 0.5 5.4 4 1 1 6 6 6 5 FNIP Repeat Ery_res_leader2 PF08057.11 GAM24170.1 - 0.045 14.1 0.2 7.6 7.4 0.1 3.4 3 0 0 3 3 3 0 Erythromycin resistance leader peptide FNIP PF05725.12 GAM24171.1 - 7.6e-05 22.8 2.6 0.0027 17.9 0.1 2.6 1 1 1 2 2 2 2 FNIP Repeat Cid2 PF09774.9 GAM24172.1 - 8.2e-09 36.1 3.6 1.1e-08 35.6 3.6 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 CCDC24 PF15669.5 GAM24172.1 - 0.0015 18.4 1.5 0.0018 18.2 1.5 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family SR-25 PF10500.9 GAM24172.1 - 0.0041 16.8 6.6 0.0042 16.7 6.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Kinesin PF00225.23 GAM24173.1 - 1.3e-93 313.6 1.9 1.3e-93 313.6 1.9 3.3 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAM24173.1 - 4.7e-19 68.8 5.6 3.6e-18 65.9 0.1 3.2 3 0 0 3 3 3 2 Microtubule binding Viral_helicase1 PF01443.18 GAM24174.1 - 0.084 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Snf7 PF03357.21 GAM24175.1 - 5e-15 55.5 15.6 5e-15 55.5 15.6 1.5 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 GAM24175.1 - 0.00032 20.7 7.0 0.00051 20.0 7.0 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SAS4 PF15460.6 GAM24175.1 - 0.032 14.3 0.4 0.032 14.3 0.4 2.7 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 AdoHcyase PF05221.17 GAM24176.1 - 1.3e-134 448.1 0.0 6.2e-74 248.8 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 GAM24176.1 - 2.1e-84 281.5 4.7 3.3e-84 280.9 4.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAM24176.1 - 1.1e-06 28.2 0.1 2.4e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GAM24176.1 - 0.0063 16.1 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 GAM24176.1 - 0.023 14.4 0.3 0.038 13.7 0.3 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.18 GAM24176.1 - 0.03 14.2 0.2 0.055 13.3 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_10 PF00852.19 GAM24177.1 - 6.4e-26 91.1 0.6 9.8e-26 90.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Laminin_G_3 PF13385.6 GAM24177.1 - 3.7e-23 82.3 0.0 7.7e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TFCD_C PF12612.8 GAM24178.1 - 1.3e-28 100.2 0.8 8.2e-28 97.5 0.1 2.8 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 GAM24178.1 - 1.4e-07 31.1 0.4 0.51 10.7 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 GAM24178.1 - 1.2e-05 25.6 0.4 0.71 10.3 0.0 4.7 4 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 GAM24178.1 - 0.0074 16.3 1.3 1.7 8.7 0.1 4.2 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAM24178.1 - 0.073 13.1 0.8 51 4.1 0.1 4.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF5634 PF18681.1 GAM24180.1 - 0.096 13.1 0.1 0.26 11.7 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5634) dUTPase PF00692.19 GAM24181.1 - 0.005 16.5 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 dUTPase GTP_EFTU PF00009.27 GAM24182.1 - 5.2e-64 215.4 0.8 7.9e-64 214.8 0.8 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAM24182.1 - 7.2e-24 83.6 0.0 1.5e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 GAM24182.1 - 8.9e-21 73.8 0.0 2.4e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 GAM24182.1 - 3.9e-12 46.4 2.1 1.3e-11 44.7 0.5 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 GAM24182.1 - 2.3e-11 43.5 0.0 5.2e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 GAM24182.1 - 8.2e-06 25.7 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 GAM24182.1 - 2.8e-05 24.2 0.2 0.00014 21.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase OAS1_C PF10421.9 GAM24183.1 - 3e-10 39.9 0.9 5.3e-10 39.1 0.9 1.3 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NFRKB_winged PF14465.6 GAM24183.1 - 0.015 15.5 2.1 7.7 6.8 0.2 3.0 2 1 1 3 3 3 0 NFRKB Winged Helix-like Glucodextran_B PF09136.10 GAM24184.1 - 0.13 12.6 0.0 16 5.9 0.0 2.9 3 0 0 3 3 3 0 Glucodextranase, domain B ILEI PF15711.5 GAM24185.1 - 1.7e-06 28.4 0.9 3.4e-06 27.4 0.9 1.5 1 1 0 1 1 1 1 Interleukin-like EMT inducer F-box-like PF12937.7 GAM24185.1 - 0.048 13.6 0.4 0.24 11.3 0.6 2.0 2 0 0 2 2 2 0 F-box-like Peptidase_M1 PF01433.20 GAM24186.1 - 1.7e-44 152.0 0.0 3e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 GAM24186.1 - 5.5e-39 132.8 0.4 1.2e-38 131.6 0.1 1.8 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 GAM24186.1 - 1.2e-17 64.7 0.7 2.6e-17 63.6 0.7 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Trp_dioxygenase PF03301.13 GAM24187.1 - 8.1e-115 383.8 6.7 1e-114 383.5 6.7 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase DNA_pol_A PF00476.20 GAM24188.1 - 2e-73 247.6 2.0 2.2e-72 244.2 0.0 3.3 3 1 0 3 3 3 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 GAM24188.1 - 1.7e-40 138.5 0.0 4.9e-40 137.0 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 GAM24188.1 - 1.3e-26 93.0 0.5 7.4e-26 90.6 0.1 2.6 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_A_exo1 PF01612.20 GAM24188.1 - 3e-11 43.3 0.0 7.1e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease HHH_5 PF14520.6 GAM24188.1 - 0.0069 17.0 0.0 0.028 15.0 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain Spt20 PF12090.8 GAM24188.1 - 0.016 14.8 24.8 0.041 13.5 24.8 1.6 1 0 0 1 1 1 0 Spt20 family DUF2122 PF09895.9 GAM24188.1 - 0.074 13.4 0.1 0.36 11.2 0.0 2.2 2 0 0 2 2 2 0 RecB-family nuclease (DUF2122) HHH PF00633.23 GAM24188.1 - 0.096 12.6 0.1 0.96 9.4 0.1 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif TERB2 PF15101.6 GAM24188.1 - 1.5 8.9 11.1 3.6 7.6 11.1 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ndc1_Nup PF09531.10 GAM24188.1 - 5.5 5.6 11.7 9.2 4.8 11.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.13 GAM24188.1 - 6.4 6.5 8.9 13 5.5 8.9 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MRP-S34 PF16053.5 GAM24189.1 - 9.3e-09 35.0 0.1 1.5e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S34 Myb_DNA-binding PF00249.31 GAM24190.1 - 9.3e-24 83.4 7.7 2.6e-13 49.9 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM24190.1 - 4.6e-19 68.4 3.7 1.3e-11 44.6 0.7 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain PHD PF00628.29 GAM24190.1 - 0.0022 17.9 7.2 0.01 15.7 7.2 2.2 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 GAM24190.1 - 0.026 14.4 0.8 0.1 12.5 0.8 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 RPA43_OB PF17875.1 GAM24190.1 - 0.066 13.8 14.5 0.64 10.6 0.9 2.9 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I DUF2681 PF10883.8 GAM24190.1 - 0.59 10.6 27.3 2.1 8.8 27.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CDC45 PF02724.14 GAM24190.1 - 1.2 7.3 17.3 1.8 6.8 6.0 2.2 2 0 0 2 2 2 0 CDC45-like protein PAS PF00989.25 GAM24190.1 - 1.7 8.6 7.1 51 3.9 0.0 2.5 2 0 0 2 2 2 0 PAS fold SDA1 PF05285.12 GAM24190.1 - 2.5 7.4 19.8 2.4 7.5 9.7 2.2 2 0 0 2 2 2 0 SDA1 NOA36 PF06524.12 GAM24190.1 - 7.5 5.8 23.2 0.019 14.3 9.1 2.7 3 0 0 3 3 3 0 NOA36 protein STAS PF01740.21 GAM24192.1 - 2e-18 66.2 0.0 2.5e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 STAS domain EcoRI_methylase PF13651.6 GAM24192.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI STAS_2 PF13466.6 GAM24192.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 STAS domain IMS PF00817.20 GAM24193.1 - 2.4e-39 134.7 0.0 4.4e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 GAM24193.1 - 0.00058 20.5 0.1 0.0023 18.6 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 GAM24193.1 - 0.0013 18.9 0.1 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 IMS family HHH motif DUF2583 PF10762.9 GAM24193.1 - 0.083 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) SmpA_OmlA PF04355.13 GAM24193.1 - 0.085 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 SmpA / OmlA family PilA4 PF18682.1 GAM24194.1 - 0.0014 19.0 0.3 0.062 13.7 0.1 2.6 1 1 1 2 2 2 1 Pilin A4 HGD-D PF06050.13 GAM24194.1 - 0.31 10.8 3.6 0.32 10.7 2.2 1.8 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component SIR2 PF02146.17 GAM24194.1 - 1.3 9.0 8.6 0.054 13.4 0.9 2.2 2 1 0 2 2 2 0 Sir2 family UQ_con PF00179.26 GAM24195.1 - 4.8e-47 159.1 0.0 5.4e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM24195.1 - 0.00088 19.0 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GAM24195.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 UEV domain G8 PF10162.9 GAM24196.1 - 1.2e-25 90.0 0.1 2.9e-25 88.7 0.1 1.7 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 GAM24196.1 - 1.3 8.9 20.8 0.041 13.7 5.2 4.0 1 1 2 3 3 3 0 Right handed beta helix region Mito_carr PF00153.27 GAM24197.1 - 3e-71 235.4 1.4 2.7e-23 81.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GAM24197.1 - 3.6e-25 88.2 9.1 1.9e-13 50.7 0.6 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAM24197.1 - 1.4e-22 77.5 13.5 1.1e-05 24.6 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_5 PF13202.6 GAM24197.1 - 2.7e-22 77.2 14.5 4.7e-06 25.9 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 GAM24197.1 - 2.1e-20 70.9 7.8 1e-05 25.1 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 GAM24197.1 - 6.3e-15 54.8 6.2 5.7e-05 22.9 0.3 4.4 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM24197.1 - 8e-13 48.7 2.5 8.7e-07 29.3 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 GAM24197.1 - 1.6e-06 27.9 2.0 0.072 13.0 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 GAM24197.1 - 0.074 13.4 0.2 12 6.3 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 GAM24197.1 - 0.078 12.9 6.5 1.1 9.2 0.3 3.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF4051 PF13260.6 GAM24199.1 - 0.046 13.5 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Cnd1 PF12717.7 GAM24200.1 - 0.0085 16.1 1.0 0.031 14.3 1.0 1.9 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 GAM24200.1 - 0.015 15.3 0.0 0.04 14.0 0.0 1.8 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAM24200.1 - 0.017 15.5 0.0 0.087 13.2 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 GAM24200.1 - 0.018 15.6 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 HEAT-like repeat HEAT PF02985.22 GAM24200.1 - 0.062 13.6 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 HEAT repeat RTP1_C1 PF10363.9 GAM24200.1 - 0.15 12.2 0.2 1.5 9.0 0.2 2.3 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 GAM24200.1 - 0.16 12.4 0.2 0.6 10.5 0.0 2.1 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RRM_1 PF00076.22 GAM24201.1 - 4.6e-16 58.4 0.3 1.2e-15 57.1 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM24201.1 - 0.063 13.4 0.1 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 GAM24201.1 - 0.084 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nop14 PF04147.12 GAM24201.1 - 0.39 8.9 35.3 0.12 10.6 32.0 1.8 2 0 0 2 2 2 0 Nop14-like family Hamartin PF04388.12 GAM24201.1 - 0.54 8.9 18.3 0.96 8.0 18.3 1.4 1 0 0 1 1 1 0 Hamartin protein CDC27 PF09507.10 GAM24201.1 - 0.88 8.9 51.7 0.95 8.8 50.2 1.8 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 BUD22 PF09073.10 GAM24201.1 - 1.5 8.1 45.5 2.4 7.4 45.5 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAM24201.1 - 3.6 5.8 19.7 5.9 5.1 19.7 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 GAM24202.1 - 2.4 8.1 25.9 4.4 7.2 25.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSase_L_D2 PF02786.17 GAM24203.1 - 2.9e-76 255.7 0.2 1e-75 253.9 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAM24203.1 - 8.7e-47 158.2 0.0 2.2e-46 156.9 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAM24203.1 - 4.9e-37 126.3 0.0 1.3e-36 124.9 0.0 1.8 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAM24203.1 - 3.5e-15 55.6 2.2 3.5e-15 55.6 2.2 2.7 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 GAM24203.1 - 3.5e-12 46.3 0.0 7.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAM24203.1 - 3.7e-12 46.1 0.0 1.6e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 GAM24203.1 - 6.1e-06 26.0 0.2 0.0019 18.0 0.1 2.9 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 GAM24203.1 - 1.7e-05 24.9 0.1 4.5e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain RnfC_N PF13375.6 GAM24203.1 - 4.7e-05 23.3 0.1 0.00015 21.6 0.1 1.9 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 GAM24203.1 - 0.00045 20.9 0.1 0.29 11.9 0.1 2.9 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 GAM24203.1 - 0.0017 18.2 0.0 0.0033 17.2 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 GAM24203.1 - 0.0046 16.6 0.0 0.024 14.2 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GCV_H PF01597.19 GAM24203.1 - 0.0062 16.4 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein ATPgrasp_ST PF14397.6 GAM24203.1 - 0.037 13.3 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp NQRA PF05896.11 GAM24203.1 - 0.038 13.4 0.1 0.093 12.2 0.1 1.6 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_D23 PF16576.5 GAM24203.1 - 0.07 12.3 0.1 0.85 8.8 0.0 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 GAM24203.1 - 0.091 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain PTS_EIIA_1 PF00358.20 GAM24203.1 - 0.095 12.5 0.1 0.63 9.8 0.1 2.2 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Spermine_synth PF01564.17 GAM24204.1 - 7.9e-06 25.4 0.1 1.4e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_31 PF13847.6 GAM24204.1 - 0.0023 17.7 0.1 0.0028 17.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 GAM24204.1 - 0.031 14.4 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 GAM24204.1 - 0.068 13.9 0.0 0.19 12.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox_2 PF07992.14 GAM24205.1 - 2.9e-30 105.5 0.6 1.3e-15 57.4 0.1 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM24205.1 - 1.9e-07 30.5 0.8 0.0012 18.0 0.1 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 GAM24205.1 - 1.1e-06 29.1 0.1 0.0049 17.4 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 GAM24205.1 - 1e-05 25.3 0.0 3.4e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 GAM24205.1 - 0.0014 17.9 1.7 0.23 10.7 0.2 3.2 2 1 2 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAM24205.1 - 0.0024 18.3 0.0 0.62 10.5 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 GAM24205.1 - 0.0025 17.5 0.4 0.011 15.3 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM24205.1 - 0.02 15.1 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Malic_M PF03949.15 GAM24205.1 - 0.042 13.1 0.2 7.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Mqo PF06039.15 GAM24205.1 - 0.084 11.4 0.0 0.72 8.3 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 GAM24205.1 - 0.15 11.3 1.2 8.5 5.5 0.0 2.9 3 0 0 3 3 3 0 FAD binding domain Abhydrolase_1 PF00561.20 GAM24206.1 - 0.00045 19.9 0.0 0.039 13.6 0.0 2.8 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAM24206.1 - 0.0014 18.5 0.0 0.069 12.9 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAM24206.1 - 0.0024 17.2 0.0 0.0088 15.3 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM24206.1 - 0.0026 17.3 0.0 0.32 10.4 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 GAM24206.1 - 0.012 14.5 0.0 0.57 9.1 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF1515 PF07439.11 GAM24207.1 - 0.76 9.8 3.2 0.9 9.6 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Z1 PF10593.9 GAM24207.1 - 1.3 8.5 7.6 1.6 8.2 7.6 1.1 1 0 0 1 1 1 0 Z1 domain COPR5 PF15340.6 GAM24207.1 - 1.4 9.5 8.1 0.58 10.8 0.2 2.1 1 1 1 2 2 2 0 Cooperator of PRMT5 family Borrelia_P83 PF05262.11 GAM24207.1 - 2.7 6.4 17.5 3.1 6.2 17.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Asp-B-Hydro_N PF05279.11 GAM24207.1 - 4.7 7.2 20.0 6.1 6.8 20.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Clat_adaptor_s PF01217.20 GAM24209.1 - 5.1e-20 71.9 2.9 6.6e-20 71.5 2.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1365 PF07103.11 GAM24209.1 - 0.048 13.3 0.1 0.057 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1365) AMP-binding PF00501.28 GAM24210.1 - 1.4e-70 238.0 0.0 1.7e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM24210.1 - 6.2e-11 43.1 0.0 1.4e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 GAM24211.1 - 2.1e-52 178.1 0.1 7.1e-51 173.1 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24211.1 - 3.6e-21 75.6 0.2 7.9e-13 48.3 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM24211.1 - 0.00036 19.6 0.9 0.00079 18.5 0.9 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM24211.1 - 0.00081 18.8 0.0 0.12 11.6 0.0 2.9 2 1 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 GAM24211.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 GAM24211.1 - 0.12 11.7 0.1 0.3 10.4 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM24211.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ThiG PF05690.14 GAM24211.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG adh_short_C2 PF13561.6 GAM24212.1 - 1.3e-49 168.9 0.1 1.9e-49 168.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM24212.1 - 7.6e-47 159.3 0.0 1.3e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM24212.1 - 8.9e-09 35.5 0.0 1.6e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM24212.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 GAM24212.1 - 0.025 14.5 0.2 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3953 PF13129.6 GAM24212.1 - 0.032 14.0 0.4 0.1 12.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) Epimerase PF01370.21 GAM24212.1 - 0.067 12.6 0.2 0.23 10.9 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cytochrom_C1 PF02167.15 GAM24213.1 - 4.2e-89 298.0 0.0 4.9e-89 297.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 GAM24213.1 - 0.0023 18.2 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 GAM24213.1 - 0.21 12.8 1.3 0.5 11.5 0.8 1.8 2 1 0 2 2 2 0 Cytochrome c UQ_con PF00179.26 GAM24214.1 - 1.5e-14 53.8 0.0 1.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAM24214.1 - 0.08 13.2 0.0 0.089 13.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain Ldh_1_C PF02866.18 GAM24215.1 - 1.6e-34 119.3 0.0 2.6e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAM24215.1 - 1.1e-30 106.6 0.1 1.7e-30 106.0 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain G-alpha PF00503.20 GAM24216.1 - 1.2e-98 330.6 9.4 1.6e-98 330.1 9.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM24216.1 - 6.9e-17 61.4 3.0 6.2e-10 38.8 0.2 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM24216.1 - 6.9e-06 25.6 2.3 0.00094 18.6 0.6 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM24216.1 - 0.0044 17.1 0.6 0.23 11.5 0.0 2.9 2 1 1 3 3 3 1 50S ribosome-binding GTPase TniB PF05621.11 GAM24216.1 - 0.013 15.0 0.3 0.028 13.8 0.3 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 GAM24216.1 - 0.013 15.8 3.3 2.6 8.3 0.1 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 GAM24216.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L13 PF00572.18 GAM24216.1 - 0.36 11.1 4.9 13 6.1 1.0 2.8 2 1 0 2 2 2 0 Ribosomal protein L13 Ribosomal_S8 PF00410.19 GAM24217.1 - 4.1e-18 65.5 0.0 5.7e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 BBS2_Mid PF14783.6 GAM24218.1 - 0.00013 22.0 0.6 5.7 7.0 0.0 4.4 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region FNIP PF05725.12 GAM24219.1 - 2.5e-63 210.0 11.6 1.3e-16 60.5 0.7 5.4 5 0 0 5 5 5 5 FNIP Repeat Metallophos_C PF14008.6 GAM24220.1 - 1.1e-17 64.6 0.3 3.5e-17 63.0 0.3 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 GAM24220.1 - 5.6e-17 62.9 0.5 1e-16 62.1 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GAM24220.1 - 4.3e-16 59.3 4.5 4.3e-16 59.3 4.5 2.9 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain RIFIN PF02009.16 GAM24220.1 - 0.8 9.5 1.6 1.2 9.0 1.6 1.3 1 0 0 1 1 1 0 Rifin DUF908 PF06012.12 GAM24220.1 - 2.2 7.6 13.5 3.6 6.9 13.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Rap_GAP PF02145.15 GAM24222.1 - 8.4e-64 214.5 0.4 8.4e-64 214.5 0.4 2.0 2 0 0 2 2 2 1 Rap/ran-GAP AAA_11 PF13086.6 GAM24222.1 - 0.0021 17.9 6.5 0.0048 16.7 6.5 1.6 1 0 0 1 1 1 1 AAA domain SET PF00856.28 GAM24222.1 - 0.063 13.7 0.3 0.16 12.4 0.2 1.8 2 0 0 2 2 2 0 SET domain SprA-related PF12118.8 GAM24222.1 - 0.13 11.4 12.7 0.04 13.1 4.5 2.2 2 0 0 2 2 2 0 SprA-related family DUF2151 PF10221.9 GAM24222.1 - 0.37 9.3 9.2 0.66 8.5 9.2 1.4 1 0 0 1 1 1 0 Cell cycle and development regulator DUF853 PF05872.12 GAM24222.1 - 0.7 8.4 6.4 1.1 7.8 6.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) NPR3 PF03666.13 GAM24222.1 - 0.71 8.6 10.6 1.5 7.5 10.6 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 GAM24222.1 - 0.93 9.3 15.9 1.9 8.2 15.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 GAM24222.1 - 1.3 7.4 15.5 2 6.8 15.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein FGF-BP1 PF06473.12 GAM24222.1 - 1.8 8.3 13.7 3.9 7.2 13.7 1.5 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) RPN2_C PF18004.1 GAM24222.1 - 2 8.3 21.1 3.1 7.7 19.0 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Connexin PF00029.19 GAM24222.1 - 2.3 7.9 10.9 4.7 6.9 10.9 1.4 1 0 0 1 1 1 0 Connexin Vfa1 PF08432.10 GAM24222.1 - 3.1 8.1 22.6 1.9 8.8 17.9 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SR-25 PF10500.9 GAM24222.1 - 4.5 6.8 36.8 0.45 10.1 0.4 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 GAM24222.1 - 5.1 6.2 4.4 8.4 5.5 4.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter NARP1 PF12569.8 GAM24222.1 - 7.9 5.3 15.6 15 4.4 15.6 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.14 GAM24222.1 - 8.2 4.6 18.1 0.22 9.8 11.5 1.6 2 0 0 2 2 2 0 CDC45-like protein Kelch_4 PF13418.6 GAM24223.1 - 1.1e-09 38.1 0.2 0.029 14.4 0.1 3.8 3 0 0 3 3 3 3 Galactose oxidase, central domain zf-B_box PF00643.24 GAM24223.1 - 1.5e-08 34.6 4.0 1.5e-08 34.6 4.0 2.5 2 0 0 2 2 2 1 B-box zinc finger Kelch_1 PF01344.25 GAM24223.1 - 5e-07 29.2 0.0 0.00076 19.0 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 GAM24223.1 - 2.2e-06 27.8 0.2 0.052 13.9 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 GAM24223.1 - 4.1e-05 23.4 1.0 0.42 10.7 0.0 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 GAM24223.1 - 0.00066 19.9 0.1 0.81 10.0 0.0 3.4 3 1 0 3 3 3 1 Galactose oxidase, central domain Plasmid_RAQPRD PF09686.10 GAM24223.1 - 0.18 12.0 0.3 0.39 11.0 0.3 1.5 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF1043 PF06295.12 GAM24223.1 - 0.69 9.9 2.9 2.8 8.0 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Acetyltransf_10 PF13673.7 GAM24224.1 - 7.1e-13 48.6 0.0 7.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM24224.1 - 5.6e-12 45.9 0.0 6.7e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM24224.1 - 1.3e-07 31.9 0.0 1.9e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM24224.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 GAM24224.1 - 0.0025 18.0 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAM24224.1 - 0.018 15.7 0.0 0.022 15.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM24224.1 - 0.044 13.9 0.1 0.17 12.0 0.1 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 GAM24224.1 - 0.068 12.9 0.1 0.19 11.5 0.1 1.7 1 1 1 2 2 2 0 GNAT acetyltransferase, Mec-17 ATPase-cat_bd PF12156.8 GAM24225.1 - 0.00096 19.8 0.1 0.001 19.7 0.1 1.1 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase Maelstrom PF13017.6 GAM24225.1 - 0.0095 15.6 0.3 0.0095 15.6 0.3 1.1 1 0 0 1 1 1 1 piRNA pathway germ-plasm component IGFL PF14653.6 GAM24225.1 - 0.011 15.6 0.3 0.012 15.6 0.3 1.1 1 0 0 1 1 1 0 Insulin growth factor-like family BRCT_3 PF18428.1 GAM24225.1 - 0.062 13.4 0.0 0.062 13.4 0.0 1.1 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain FNIP PF05725.12 GAM24226.1 - 1.8e-10 40.8 12.1 0.00087 19.4 0.1 5.5 5 1 0 5 5 5 3 FNIP Repeat LRR_8 PF13855.6 GAM24226.1 - 0.037 13.8 6.3 0.87 9.4 0.1 4.4 4 0 0 4 4 4 0 Leucine rich repeat PH_12 PF16457.5 GAM24226.1 - 0.038 14.5 1.0 2.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain LRR_4 PF12799.7 GAM24226.1 - 0.049 14.1 19.2 6.6 7.3 0.1 6.6 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) BCIP PF13862.6 GAM24227.1 - 0.079 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 p21-C-terminal region-binding protein RCC1 PF00415.18 GAM24228.1 - 4.6e-38 129.6 14.4 2.4e-08 34.5 0.0 8.4 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM24228.1 - 5.7e-29 99.3 35.5 2e-06 27.4 0.1 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Profilin PF00235.19 GAM24228.1 - 7.8e-09 35.9 1.4 4.5e-08 33.4 1.4 2.1 1 1 0 1 1 1 1 Profilin Kelch_4 PF13418.6 GAM24228.1 - 0.0014 18.6 3.1 11 6.1 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Reg_prop PF07494.11 GAM24228.1 - 0.08 13.2 0.2 12 6.5 0.0 4.1 4 0 0 4 4 4 0 Two component regulator propeller GMC_oxred_N PF00732.19 GAM24229.1 - 9.6e-41 140.1 0.0 1.9e-40 139.1 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM24229.1 - 3e-21 76.5 0.0 5.6e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAM24229.1 - 0.0031 16.6 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAM24229.1 - 0.015 14.6 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TMEM240 PF15207.6 GAM24229.1 - 0.12 12.1 0.0 0.75 9.5 0.0 2.0 2 0 0 2 2 2 0 TMEM240 family RabGAP-TBC PF00566.18 GAM24230.1 - 8.3e-45 153.1 5.1 8.3e-45 153.1 5.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Glyco_hydro_20 PF00728.22 GAM24231.1 - 8.6e-85 285.2 1.2 1.1e-84 284.9 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAM24231.1 - 7.9e-15 55.7 0.0 1.8e-13 51.3 0.0 2.3 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAM24231.1 - 0.00044 21.0 0.3 0.0038 18.0 0.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 SR-25 PF10500.9 GAM24233.1 - 0.0059 16.2 10.0 0.0086 15.7 10.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 GAM24233.1 - 0.011 15.8 26.5 0.017 15.1 26.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ETRAMP PF09716.10 GAM24233.1 - 0.022 14.8 0.1 0.033 14.3 0.1 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Connexin PF00029.19 GAM24233.1 - 0.65 9.7 4.0 0.16 11.7 0.7 1.5 2 0 0 2 2 2 0 Connexin Peptidase_S49_N PF08496.10 GAM24233.1 - 1.1 9.3 8.6 1.9 8.5 8.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1115 PF06544.12 GAM24233.1 - 1.9 8.6 8.8 14 5.8 7.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1115) CxC6 PF18721.1 GAM24233.1 - 2.2 8.6 7.0 0.12 12.7 1.4 1.8 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Conotoxin PF02950.17 GAM24233.1 - 2.4 9.3 4.2 3.1 8.9 1.6 2.2 2 0 0 2 2 2 0 Conotoxin Alk_phosphatase PF00245.20 GAM24233.1 - 7.3 5.4 8.5 0.68 8.8 1.0 2.4 2 1 1 3 3 3 0 Alkaline phosphatase zf-RING_2 PF13639.6 GAM24234.1 - 3.7e-11 43.2 5.9 4.6e-11 42.9 4.7 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAM24234.1 - 6.2e-09 35.4 3.7 1.2e-08 34.5 3.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAM24234.1 - 1.8e-07 30.8 5.2 1.8e-07 30.8 5.2 2.3 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM24234.1 - 6.3e-07 29.6 9.2 1.1e-05 25.6 9.4 2.7 1 1 1 2 2 2 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 GAM24234.1 - 9.1e-06 25.2 5.7 2.1e-05 24.0 5.7 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 GAM24234.1 - 5.3e-05 23.0 7.2 0.00024 20.9 7.4 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAM24234.1 - 0.00013 22.0 4.6 0.00037 20.5 4.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 GAM24234.1 - 0.0006 19.7 5.3 0.0016 18.4 5.1 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM24234.1 - 0.00083 19.3 4.6 0.002 18.1 4.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 GAM24234.1 - 0.0066 16.6 3.6 0.015 15.5 3.6 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Nse PF11789.8 GAM24234.1 - 0.026 14.3 5.1 0.069 13.0 5.1 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 GAM24234.1 - 0.065 13.2 5.6 0.24 11.4 5.6 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 RINGv PF12906.7 GAM24234.1 - 0.1 12.8 2.7 0.26 11.4 2.7 1.7 1 0 0 1 1 1 0 RING-variant domain SMYLE_N PF18615.1 GAM24234.1 - 0.54 9.8 22.5 0.0091 15.6 12.4 2.1 1 1 2 3 3 3 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DNA_pol_phi PF04931.13 GAM24234.1 - 5.5 5.0 13.3 1.8 6.6 10.8 1.5 2 0 0 2 2 2 0 DNA polymerase phi Methyltr_RsmB-F PF01189.17 GAM24235.1 - 8.1e-75 250.9 0.0 1.9e-74 249.6 0.0 1.7 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 GAM24235.1 - 1.4e-09 38.3 0.0 4e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 GAM24235.1 - 5.6e-05 23.3 0.0 0.0027 17.8 0.0 2.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.16 GAM24235.1 - 0.00093 19.0 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 GAM24235.1 - 0.026 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 GAM24235.1 - 0.06 14.1 0.0 0.24 12.1 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 GAM24236.1 - 4e-69 232.9 0.6 7.6e-69 232.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24236.1 - 8.1e-47 159.7 0.0 1.7e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAM24236.1 - 6.6e-14 52.0 0.5 6.6e-14 52.0 0.5 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 GAM24236.1 - 4.1e-06 25.8 0.0 4.1e-06 25.8 0.0 2.6 2 1 0 2 2 2 1 Fungal protein kinase DUF572 PF04502.13 GAM24236.1 - 0.001 18.8 28.0 0.0014 18.4 27.1 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF1356 PF07092.12 GAM24236.1 - 0.048 12.9 0.8 0.47 9.7 0.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1356) PAC4 PF16093.5 GAM24236.1 - 0.1 12.8 0.8 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Chromo PF00385.24 GAM24237.1 - 4.9e-13 48.8 0.8 4.9e-13 48.8 0.8 2.6 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain PBP1_TM PF14812.6 GAM24237.1 - 0.002 18.4 6.7 0.002 18.4 6.7 4.4 2 1 2 4 4 4 2 Transmembrane domain of transglycosylase PBP1 at N-terminal Mtf2_C PF14061.6 GAM24237.1 - 0.12 12.5 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 CENP-B_dimeris PF09026.10 GAM24237.1 - 0.69 10.3 39.6 0.12 12.8 4.6 4.3 4 0 0 4 4 4 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 GAM24237.1 - 1.1 7.2 53.5 0.06 11.5 10.0 2.4 2 1 1 3 3 3 0 DNA polymerase phi BUD22 PF09073.10 GAM24237.1 - 8.2 5.7 69.8 2.3 7.4 21.2 2.1 1 1 1 2 2 2 0 BUD22 ATG_C PF09333.11 GAM24239.1 - 1.1e-13 51.3 4.2 2.3e-06 27.9 0.0 3.0 3 1 1 4 4 4 2 Autophagy-related protein C terminal domain VPS13_C PF16909.5 GAM24239.1 - 2.8e-05 24.0 8.5 0.016 15.0 1.1 3.2 2 1 1 3 3 3 3 Vacuolar-sorting-associated 13 protein C-terminal zf-B_box PF00643.24 GAM24239.1 - 0.00077 19.6 4.2 0.0017 18.5 4.2 1.5 1 0 0 1 1 1 1 B-box zinc finger MMR1 PF08505.10 GAM24239.1 - 1.3 9.3 27.4 0.026 14.8 11.7 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein XRN_M PF17846.1 GAM24239.1 - 2.6 6.9 15.8 3.8 6.3 4.5 2.2 2 0 0 2 2 2 0 Xrn1 helical domain Spt20 PF12090.8 GAM24239.1 - 6.2 6.4 27.5 0.25 10.9 14.6 2.3 2 0 0 2 2 2 0 Spt20 family Lactamase_B_4 PF13691.6 GAM24240.1 - 1.4e-11 43.9 0.1 1.6e-10 40.5 0.0 2.5 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 GAM24240.1 - 1.8e-11 44.0 0.1 4.9e-08 32.7 0.3 2.9 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAM24240.1 - 0.15 12.1 0.1 0.44 10.5 0.1 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily adh_short_C2 PF13561.6 GAM24241.1 - 1.9e-47 161.8 0.0 2.5e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM24241.1 - 6e-44 149.8 0.0 8e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM24241.1 - 1.2e-13 51.4 0.0 1.6e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAM24241.1 - 0.00013 21.3 0.2 0.0037 16.6 0.1 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 GAM24241.1 - 0.00028 20.4 0.0 0.0016 17.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NDUF_C2 PF06374.11 GAM24242.1 - 8.1e-05 22.7 0.8 0.00045 20.3 0.2 1.9 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) BST2 PF16716.5 GAM24243.1 - 0.0095 16.5 1.3 0.0095 16.5 1.3 3.9 3 0 0 3 3 3 1 Bone marrow stromal antigen 2 YrbL-PhoP_reg PF10707.9 GAM24243.1 - 0.19 11.3 5.5 0.79 9.2 0.0 2.9 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Metallophos_2 PF12850.7 GAM24244.1 - 3.5e-22 79.4 0.3 4.4e-22 79.0 0.3 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 GAM24244.1 - 0.00051 20.6 1.2 1.2 9.6 0.1 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase PH PF00169.29 GAM24245.1 - 1.7e-12 47.7 0.0 4.1e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 PH domain 2-oxoacid_dh PF00198.23 GAM24246.1 - 2.2e-69 233.4 0.1 3.1e-69 233.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 GAM24246.1 - 1.9e-10 40.9 0.0 2.6e-09 37.3 0.0 2.4 2 0 0 2 2 2 1 e3 binding domain MGC-24 PF05283.11 GAM24246.1 - 9 6.7 11.9 23 5.4 11.9 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mito_carr PF00153.27 GAM24247.1 - 2.2e-66 219.8 3.8 2.2e-24 85.2 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein AvrE_T3Es PF11725.8 GAM24247.1 - 0.19 8.9 0.8 0.26 8.5 0.8 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) NIF3 PF01784.18 GAM24248.1 - 2.2e-64 217.4 0.0 2.8e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) NTP_transf_3 PF12804.7 GAM24248.1 - 0.11 12.9 0.0 0.47 10.8 0.0 1.9 2 0 0 2 2 2 0 MobA-like NTP transferase domain CDK5_activator PF03261.15 GAM24249.1 - 0.011 15.3 6.7 0.013 15.1 6.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein NADH_u_ox_C PF12853.7 GAM24249.1 - 0.022 14.7 2.0 0.022 14.7 2.0 2.0 2 1 0 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF4200 PF13863.6 GAM24249.1 - 0.035 14.5 23.1 0.3 11.5 23.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) FPP PF05911.11 GAM24249.1 - 0.16 10.1 17.5 0.19 9.9 17.5 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil UPF0242 PF06785.11 GAM24249.1 - 0.38 10.8 23.0 0.1 12.7 16.4 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ATP-synt_E PF05680.12 GAM24249.1 - 1.3 9.5 8.5 0.92 9.9 4.8 2.2 1 1 1 2 2 2 0 ATP synthase E chain DUF948 PF06103.11 GAM24249.1 - 1.6 9.0 6.8 0.45 10.8 1.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 GAM24249.1 - 2.4 8.2 9.0 1.6 8.8 4.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TLE_N PF03920.15 GAM24249.1 - 3.1 7.9 11.1 7.3 6.7 4.8 2.3 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Fez1 PF06818.15 GAM24249.1 - 3.5 8.0 18.3 7.3 7.0 18.3 1.4 1 1 0 1 1 1 0 Fez1 Exonuc_VII_L PF02601.15 GAM24249.1 - 6.3 6.3 9.4 7.7 6.0 9.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PEPCK_ATP PF01293.20 GAM24250.1 - 4.6e-27 94.8 0.3 6e-14 51.6 0.0 2.7 2 1 0 2 2 2 2 Phosphoenolpyruvate carboxykinase Rax2 PF12768.7 GAM24250.1 - 0.027 14.0 0.3 0.051 13.0 0.3 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity CTC1 PF15489.6 GAM24251.1 - 6.9e-05 20.6 0.0 0.00029 18.5 0.0 1.9 1 1 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 Ank_2 PF12796.7 GAM24252.1 - 0.00055 20.5 0.1 0.16 12.6 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Tricorn_C1 PF14684.6 GAM24252.1 - 0.057 13.5 0.5 0.14 12.3 0.5 1.6 1 0 0 1 1 1 0 Tricorn protease C1 domain Ank_4 PF13637.6 GAM24252.1 - 0.081 13.5 2.8 62 4.3 0.0 4.7 4 2 0 5 5 5 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM24252.1 - 0.11 12.9 2.8 32 5.0 0.1 5.1 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM24252.1 - 1 10.2 7.8 14 6.6 0.0 5.7 7 0 0 7 7 7 0 Ankyrin repeat Sortilin-Vps10 PF15902.5 GAM24253.1 - 2.4e-23 82.7 0.4 7.1e-05 21.8 0.0 5.8 3 2 1 5 5 5 5 Sortilin, neurotensin receptor 3, BNR PF02012.20 GAM24253.1 - 2.5e-10 38.8 42.0 1.6 9.0 0.1 9.9 9 0 0 9 9 9 8 BNR/Asp-box repeat BNR_2 PF13088.6 GAM24253.1 - 7.3e-08 32.0 11.3 0.007 15.7 2.3 6.2 3 2 1 4 4 4 2 BNR repeat-like domain BNR_6 PF15899.5 GAM24253.1 - 2.5e-07 30.1 8.5 1.5 9.1 0.0 8.2 9 0 0 9 9 9 2 BNR-Asp box repeat PSII_BNR PF14870.6 GAM24253.1 - 2.8e-07 30.1 15.6 0.065 12.5 1.1 6.0 2 2 3 5 5 5 3 Photosynthesis system II assembly factor YCF48 BNR_3 PF13859.6 GAM24253.1 - 0.33 10.2 14.4 17 4.6 0.0 6.1 5 1 1 6 6 6 0 BNR repeat-like domain DUF5041 PF16444.5 GAM24254.1 - 0.23 11.7 2.0 1.2 9.3 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5041) DivIC PF04977.15 GAM24254.1 - 0.69 9.7 8.9 1.5 8.6 8.9 1.5 1 0 0 1 1 1 0 Septum formation initiator TFIIA PF03153.13 GAM24254.1 - 2.2 8.2 20.0 3.7 7.5 20.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM PF10378.9 GAM24254.1 - 3.4 7.5 10.0 3.8 7.3 2.5 2.8 1 1 1 2 2 2 0 Putative RRM domain UQ_con PF00179.26 GAM24255.1 - 5.2e-42 142.8 0.0 5.9e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM24255.1 - 0.00056 19.6 0.0 0.0006 19.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Ras PF00071.22 GAM24256.1 - 8.4e-57 191.3 0.0 9.8e-57 191.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24256.1 - 8.7e-23 80.8 0.0 1.5e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24256.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family RGS PF00615.19 GAM24257.1 - 8.2e-17 61.6 3.9 2.2e-12 47.3 0.3 2.5 2 1 0 2 2 2 2 Regulator of G protein signaling domain RGS-like PF09128.11 GAM24257.1 - 0.0073 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain Sec3_C PF09763.9 GAM24258.1 - 6.7e-146 487.5 18.6 8.5e-146 487.2 18.6 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 OGG_N PF07934.12 GAM24258.1 - 0.025 14.7 1.7 3.7 7.7 0.0 3.0 2 0 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain DUF4294 PF14127.6 GAM24258.1 - 0.1 12.5 8.6 0.052 13.5 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) HBM PF16591.5 GAM24258.1 - 0.21 11.0 6.0 1.1 8.6 0.2 2.9 2 1 1 3 3 3 0 Helical bimodular sensor domain Ank_2 PF12796.7 GAM24259.1 - 1.7e-32 111.9 3.1 5.8e-21 74.9 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM24259.1 - 8.4e-32 109.2 5.6 1.1e-10 41.9 0.0 5.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM24259.1 - 1.6e-27 95.2 4.3 4.2e-10 39.7 0.9 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM24259.1 - 1e-25 89.0 9.8 2.6e-07 30.8 0.1 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 GAM24259.1 - 4.6e-24 81.9 4.1 7.5e-06 25.9 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Bromodomain PF00439.25 GAM24259.1 - 1.3e-22 79.6 2.6 2.7e-22 78.6 2.6 1.6 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 GAM24259.1 - 1.4e-19 70.4 0.2 1.4e-19 70.4 0.2 2.6 3 0 0 3 3 3 1 BTB/POZ domain BET PF17035.5 GAM24259.1 - 1.8e-10 40.8 4.2 3.1e-10 40.1 2.3 2.2 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation DUF2179 PF10035.9 GAM24259.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) BACK PF07707.15 GAM24259.1 - 0.88 9.7 3.0 10 6.3 0.0 3.2 3 1 1 4 4 4 0 BTB And C-terminal Kelch HNF-1_N PF04814.13 GAM24259.1 - 6.1 7.4 15.8 0.26 11.9 4.2 2.9 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Ras PF00071.22 GAM24261.1 - 3e-53 179.7 0.0 1.7e-52 177.3 0.0 2.2 2 0 0 2 2 2 1 Ras family BTB PF00651.31 GAM24261.1 - 1e-34 119.1 7.2 2.5e-19 69.5 0.2 3.4 2 1 0 2 2 2 2 BTB/POZ domain Roc PF08477.13 GAM24261.1 - 7.2e-20 71.4 0.0 2.6e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24261.1 - 4.8e-05 22.9 0.0 0.00023 20.7 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family BTB_3 PF16017.5 GAM24261.1 - 0.00041 20.4 1.5 0.4 10.8 0.1 3.0 3 0 0 3 3 3 2 BTB/POZ domain BACK PF07707.15 GAM24261.1 - 0.00099 19.2 0.7 0.017 15.2 0.1 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch GTP_EFTU PF00009.27 GAM24261.1 - 0.0043 16.6 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM24261.1 - 0.016 15.3 0.0 2.3 8.3 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase Ribosomal_S17 PF00366.20 GAM24261.1 - 0.074 13.2 0.0 0.3 11.2 0.0 2.1 1 0 0 1 1 1 0 Ribosomal protein S17 Translin PF01997.16 GAM24262.1 - 2.9e-57 194.0 8.0 3.2e-57 193.8 8.0 1.0 1 0 0 1 1 1 1 Translin family LktC PF06261.11 GAM24262.1 - 0.00029 20.8 0.4 0.00029 20.8 0.4 2.0 2 2 1 3 3 3 1 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Galactosyl_T PF01762.21 GAM24262.1 - 0.0029 17.4 1.7 0.0048 16.7 1.6 1.5 1 1 0 1 1 1 1 Galactosyltransferase Rad17 PF03215.15 GAM24263.1 - 4.5e-25 88.7 0.4 1.2e-24 87.3 0.4 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain T2SSE PF00437.20 GAM24263.1 - 0.0017 17.4 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 GAM24263.1 - 0.0018 18.8 0.0 0.009 16.5 0.0 2.2 1 0 0 1 1 1 1 ABC transporter AAA_assoc_2 PF16193.5 GAM24263.1 - 0.0027 18.0 0.0 0.0078 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 GAM24263.1 - 0.0038 16.6 0.1 0.025 14.0 0.1 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 GAM24263.1 - 0.022 15.0 0.1 0.11 12.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 GAM24263.1 - 0.025 14.6 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 GAM24263.1 - 0.049 13.3 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAM24263.1 - 0.054 13.9 0.1 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAM24263.1 - 0.079 13.5 0.3 1.5 9.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Chalcone_2 PF16035.5 GAM24264.1 - 6.4e-24 84.9 0.8 2.2e-23 83.1 0.8 1.8 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 GAM24264.1 - 0.0014 18.8 0.2 0.03 14.5 0.2 2.1 1 1 0 1 1 1 1 Chalcone isomerase-like Ras PF00071.22 GAM24265.1 - 6.5e-31 107.1 0.0 7.5e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24265.1 - 6.3e-24 84.5 0.0 9.5e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24265.1 - 5.5e-13 48.7 0.0 7.4e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM24265.1 - 1.9e-06 27.4 0.0 2.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM24265.1 - 7.8e-06 26.0 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 GAM24265.1 - 0.00033 20.1 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein SRPRB PF09439.10 GAM24265.1 - 0.017 14.6 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GAM24265.1 - 0.034 13.7 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 GAM24265.1 - 0.057 13.7 0.1 0.083 13.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM24265.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Gln-synt_N PF03951.19 GAM24265.1 - 0.078 12.7 0.1 9 6.1 0.0 2.3 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain AAA_28 PF13521.6 GAM24265.1 - 0.081 13.2 0.1 0.2 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 GAM24265.1 - 0.11 11.7 0.9 4.2 6.4 0.1 2.5 1 1 2 3 3 3 0 G-protein alpha subunit AAA_16 PF13191.6 GAM24265.1 - 0.11 12.9 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 GAM24265.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 GAM24265.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 NTPase EGF_2 PF07974.13 GAM24266.1 - 1.3e-07 31.8 30.5 0.00048 20.4 8.9 2.6 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 GAM24266.1 - 2.2e-05 24.7 25.9 0.0016 18.7 6.9 2.5 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 GAM24266.1 - 0.032 14.9 22.4 0.049 14.3 2.2 3.0 3 0 0 3 3 3 0 Human growth factor-like EGF Laminin_EGF PF00053.24 GAM24266.1 - 2.3 8.4 20.9 5.2 7.3 10.3 2.4 1 1 1 2 2 2 0 Laminin EGF domain Asn_synthase PF00733.21 GAM24267.1 - 1.1e-09 38.4 0.1 1.6e-06 28.1 0.1 2.3 1 1 0 1 1 1 1 Asparagine synthase Ras PF00071.22 GAM24268.1 - 1.4e-55 187.3 0.0 1.6e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24268.1 - 4.8e-22 78.4 0.0 7.7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24268.1 - 1.6e-09 37.5 0.0 2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM24268.1 - 5.5e-05 22.8 0.0 0.00021 20.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TPR_1 PF00515.28 GAM24269.1 - 2.5e-05 23.9 3.2 0.00013 21.6 0.0 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM24269.1 - 5.3e-05 23.0 0.4 0.0013 18.7 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM24269.1 - 0.00013 22.1 0.2 0.58 10.7 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM24269.1 - 0.00034 21.1 0.5 0.0049 17.3 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM24269.1 - 0.00089 19.3 0.1 0.0047 17.0 0.1 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM24269.1 - 0.0019 18.3 0.0 0.0066 16.6 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM24269.1 - 0.0082 16.9 0.0 0.027 15.3 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM24269.1 - 0.0092 16.6 0.0 0.11 13.2 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM24269.1 - 0.018 15.3 0.2 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAM24269.1 - 0.026 14.8 0.1 0.14 12.5 0.1 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_15 PF13429.6 GAM24269.1 - 0.037 13.3 0.0 0.099 11.8 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat FNIP PF05725.12 GAM24270.1 - 1.1e-61 204.7 22.3 1.4e-14 54.0 0.2 7.1 4 1 2 7 7 7 7 FNIP Repeat DUF1769 PF08588.10 GAM24270.1 - 0.028 14.6 0.6 5.5 7.3 0.0 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1769) DUF167 PF02594.16 GAM24271.1 - 4.2e-22 78.0 0.2 5.3e-22 77.7 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 HSDR_N_2 PF13588.6 GAM24271.1 - 0.065 13.2 0.1 0.094 12.7 0.1 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) WD40 PF00400.32 GAM24272.1 - 8.6e-12 45.4 9.3 0.085 13.8 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM24272.1 - 0.00047 20.4 0.1 1.8 8.9 0.0 3.4 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NTF2 PF02136.20 GAM24273.1 - 4.9e-20 72.3 0.3 1.2e-19 71.0 0.3 1.7 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 GAM24273.1 - 3.4e-06 26.8 0.1 7e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.10 GAM24273.1 - 0.00023 20.6 12.1 0.00023 20.6 12.1 2.2 2 0 0 2 2 2 1 BUD22 YdjM PF04307.14 GAM24273.1 - 1 8.7 3.0 4.2 6.7 0.1 2.1 2 0 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase Ssl1 PF04056.14 GAM24274.1 - 5e-70 235.2 0.7 6.8e-70 234.8 0.7 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 GAM24274.1 - 1.5e-15 57.2 24.5 3.7e-15 55.9 11.1 2.9 2 1 0 2 2 2 2 TFIIH C1-like domain VWA_2 PF13519.6 GAM24274.1 - 3.5e-10 40.5 0.1 6.1e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF717 PF05338.12 GAM24274.1 - 0.13 12.4 1.3 0.18 12.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF717) UPF0547 PF10571.9 GAM24274.1 - 0.14 12.2 16.2 1.9 8.6 4.7 3.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc_ribbon_15 PF17032.5 GAM24274.1 - 2.9 8.7 16.8 0.16 12.8 9.4 2.3 2 0 0 2 2 2 0 zinc-ribbon family zf-C3HC4_3 PF13920.6 GAM24274.1 - 6.4 6.7 24.9 0.11 12.4 9.2 3.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SRR1 PF07985.12 GAM24275.1 - 1.5e-15 56.9 0.1 2.4e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 SRR1 Mon1 PF03164.14 GAM24277.1 - 7.6e-14 51.6 13.3 8.1e-13 48.2 3.6 2.4 2 0 0 2 2 2 2 Trafficking protein Mon1 PG_binding_1 PF01471.18 GAM24277.1 - 8.6e-11 41.9 0.1 1.8e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Vasculin PF15337.6 GAM24277.1 - 0.45 11.4 5.4 0.53 11.2 0.7 3.3 2 1 0 2 2 2 0 Vascular protein family Vasculin-like 1 Lon_C PF05362.13 GAM24278.1 - 3.8e-67 225.8 0.0 6.9e-67 225.0 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 GAM24278.1 - 2.9e-23 82.8 0.0 7.2e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM24278.1 - 2e-06 27.8 0.0 4.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAM24278.1 - 6.3e-06 26.4 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) LON_substr_bdg PF02190.16 GAM24278.1 - 2.7e-05 24.2 0.0 9.6e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 GAM24278.1 - 5.8e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 GAM24278.1 - 0.00031 19.8 0.0 0.00071 18.6 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 GAM24278.1 - 0.002 18.4 0.4 0.25 11.6 0.4 2.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 GAM24278.1 - 0.0029 18.1 0.0 0.0029 18.1 0.0 2.6 3 0 0 3 3 2 1 AAA domain MCM PF00493.23 GAM24278.1 - 0.0042 16.2 0.0 0.013 14.6 0.0 1.8 1 1 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 GAM24278.1 - 0.0048 17.3 0.5 0.037 14.4 0.1 2.4 2 1 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 GAM24278.1 - 0.0062 16.9 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 GAM24278.1 - 0.008 15.9 0.0 0.031 14.0 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 GAM24278.1 - 0.029 14.2 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAM24278.1 - 0.03 14.1 0.0 0.16 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAM24278.1 - 0.032 14.1 0.4 2.1 8.3 0.1 2.5 1 1 1 2 2 2 0 NTPase AAA_18 PF13238.6 GAM24278.1 - 0.035 14.6 0.0 0.074 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM24278.1 - 0.05 14.1 1.8 0.37 11.3 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 GAM24278.1 - 0.055 13.8 0.2 0.44 10.9 0.1 2.5 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 GAM24278.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 GAM24278.1 - 0.074 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 GAM24278.1 - 0.11 11.6 1.4 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain ClpB_D2-small PF10431.9 GAM24278.1 - 0.11 12.5 0.1 0.48 10.5 0.1 2.0 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein DUF1751 PF08551.10 GAM24279.1 - 2.5e-23 82.5 5.1 6e-23 81.3 5.1 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 GAM24279.1 - 3.8e-08 33.4 10.4 3.8e-08 33.4 10.4 1.6 2 0 0 2 2 2 1 Rhomboid family Androgen_recep PF02166.16 GAM24279.1 - 0.11 11.4 4.3 0.13 11.1 4.3 1.1 1 0 0 1 1 1 0 Androgen receptor Med3 PF11593.8 GAM24279.1 - 0.67 9.1 9.6 0.85 8.7 9.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2967 PF11179.8 GAM24279.1 - 5.7 4.9 10.6 7 4.6 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Arf PF00025.21 GAM24281.1 - 1.4e-29 102.8 0.0 1.7e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAM24281.1 - 3.4e-06 26.6 0.9 6.8e-06 25.6 0.9 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM24281.1 - 3.5e-06 27.1 0.7 3e-05 24.1 0.7 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 GAM24281.1 - 2.8e-05 23.8 0.1 6e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAM24281.1 - 3.4e-05 24.0 0.3 0.00015 22.0 0.3 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 GAM24281.1 - 8.2e-05 22.3 0.3 0.24 10.9 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 GAM24281.1 - 0.0009 18.5 2.4 0.19 10.8 0.3 2.4 2 1 0 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 GAM24281.1 - 0.0023 17.5 0.1 1.9 8.0 0.1 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 GAM24281.1 - 0.0051 16.7 0.1 0.0099 15.8 0.1 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea MobB PF03205.14 GAM24281.1 - 0.012 15.5 0.5 0.022 14.6 0.1 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.18 GAM24281.1 - 0.022 14.3 0.2 0.49 9.9 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 GAM24281.1 - 0.036 13.5 0.1 0.12 11.8 0.0 1.8 3 0 0 3 3 3 0 Bacterial TniB protein AAA_14 PF13173.6 GAM24281.1 - 0.059 13.4 0.1 0.1 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAM24281.1 - 0.11 12.8 0.4 1 9.6 0.4 2.0 1 1 0 1 1 1 0 AAA domain Arv1 PF04161.13 GAM24282.1 - 2e-48 165.4 7.2 2.5e-48 165.0 7.2 1.2 1 0 0 1 1 1 1 Arv1-like family DZR PF12773.7 GAM24282.1 - 0.054 13.5 0.2 0.091 12.8 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_L3 PF00297.22 GAM24283.1 - 7.2e-17 61.4 3.7 4.1e-15 55.6 1.7 2.5 2 1 0 2 2 2 1 Ribosomal protein L3 MFS_1 PF07690.16 GAM24284.1 - 5.4e-44 150.5 59.9 1.5e-35 122.8 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAM24284.1 - 0.011 14.1 9.9 0.027 12.7 1.6 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SR-25 PF10500.9 GAM24284.1 - 1.2 8.7 4.9 0.62 9.6 1.9 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 GAM24285.1 - 0.069 11.9 6.9 0.1 11.4 6.9 1.1 1 0 0 1 1 1 0 Presenilin DUF5327 PF17261.2 GAM24285.1 - 7.1 7.5 18.0 5.6 7.8 9.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Na_H_Exchanger PF00999.21 GAM24286.1 - 7.1e-43 146.8 35.3 2.4e-24 85.8 13.5 2.1 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.12 GAM24286.1 - 1.4e-05 25.0 6.2 1.4e-05 25.0 6.2 2.2 2 1 1 3 3 3 1 Predicted Permease Membrane Region DUF2781 PF10914.8 GAM24286.1 - 0.56 10.6 4.4 0.37 11.2 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2781) Tweety PF04906.13 GAM24287.1 - 2.6e-12 46.1 5.2 3.4e-08 32.6 1.0 2.1 1 1 1 2 2 2 2 Tweety Tetraspanin PF00335.20 GAM24287.1 - 0.006 16.3 1.6 0.075 12.7 0.1 2.3 2 0 0 2 2 2 1 Tetraspanin family Amastin PF07344.11 GAM24287.1 - 0.0062 16.4 6.7 0.035 13.9 0.7 2.3 2 0 0 2 2 2 2 Amastin surface glycoprotein DUF2207 PF09972.9 GAM24287.1 - 0.027 13.2 3.9 1.4 7.6 3.9 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Wzy_C PF04932.15 GAM24287.1 - 0.04 13.5 1.1 0.55 9.8 0.1 2.3 2 0 0 2 2 2 0 O-Antigen ligase Shisa PF13908.6 GAM24287.1 - 0.059 13.6 1.8 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator EpmC PF04315.12 GAM24287.1 - 0.07 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Elongation factor P hydroxylase DUF4131 PF13567.6 GAM24287.1 - 0.29 10.8 2.5 0.89 9.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_L14 PF00238.19 GAM24288.1 - 1.4e-30 105.9 0.1 1.6e-30 105.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e EF-hand_1 PF00036.32 GAM24289.1 - 9.4e-09 34.2 0.0 0.00083 18.7 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAM24289.1 - 1.8e-08 33.6 0.0 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAM24289.1 - 2.6e-08 33.6 0.0 1.8e-05 24.5 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM24289.1 - 7.9e-08 31.5 0.0 7.9e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAM24289.1 - 7.6e-07 29.5 0.0 1.1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair CvfB_WH PF17783.1 GAM24289.1 - 0.25 11.2 0.1 0.41 10.5 0.1 1.2 1 0 0 1 1 1 0 CvfB-like winged helix domain Sulf_transp PF04143.14 GAM24290.1 - 1e-51 176.3 21.0 1.3e-51 176.0 21.0 1.1 1 0 0 1 1 1 1 Sulphur transport Y_Y_Y PF07495.13 GAM24293.1 - 0.0048 16.8 15.6 0.045 13.7 0.5 4.5 4 0 0 4 4 4 2 Y_Y_Y domain CarboxypepD_reg PF13620.6 GAM24293.1 - 0.014 15.6 1.9 3.7 7.9 0.0 3.6 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain TcfC PF16967.5 GAM24293.1 - 0.098 12.2 0.0 0.71 9.4 0.0 2.3 2 0 0 2 2 2 0 E-set like domain SKG6 PF08693.10 GAM24293.1 - 0.28 10.6 2.5 0.63 9.5 2.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RNA_helicase PF00910.22 GAM24294.1 - 0.00061 20.1 0.0 0.0018 18.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase RHSP PF07999.11 GAM24294.1 - 0.0014 17.5 0.0 0.036 12.9 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon hot spot protein GvpG PF05120.12 GAM24294.1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G NACHT PF05729.12 GAM24294.1 - 0.098 12.6 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain SHOCT PF09851.9 GAM24294.1 - 0.23 11.2 3.1 0.42 10.4 3.1 1.5 1 0 0 1 1 1 0 Short C-terminal domain DPBB_1 PF03330.18 GAM24295.1 - 1.6e-05 25.1 0.8 0.00061 20.0 0.7 2.8 2 1 0 2 2 2 1 Lytic transglycolase PHD PF00628.29 GAM24296.1 - 1.2e-05 25.1 21.2 5.4e-05 23.0 5.3 3.0 3 0 0 3 3 3 2 PHD-finger Prok-RING_1 PF14446.6 GAM24296.1 - 0.0029 17.5 2.6 0.0029 17.5 2.6 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 GAM24296.1 - 0.01 15.7 2.9 0.01 15.7 2.9 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HDA2-3 PF11496.8 GAM24296.1 - 0.017 14.3 3.0 0.062 12.4 2.8 1.8 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.6 GAM24296.1 - 0.13 11.8 12.8 0.3 10.7 2.4 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 GAM24296.1 - 0.23 11.6 14.8 0.16 12.1 11.2 2.7 1 1 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 GAM24296.1 - 6.4 6.4 19.1 0.91 9.1 11.5 2.9 2 1 1 3 3 3 0 PHD-finger SUIM_assoc PF16619.5 GAM24297.1 - 0.071 13.2 0.4 0.071 13.2 0.4 5.8 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 BLOC1_2 PF10046.9 GAM24297.1 - 0.24 11.7 6.4 0.77 10.1 6.4 1.9 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Peptidase_C65 PF10275.9 GAM24297.1 - 0.98 8.8 7.4 2.5 7.5 7.4 1.6 1 0 0 1 1 1 0 Peptidase C65 Otubain Herpes_LAMP2 PF06126.11 GAM24297.1 - 4.3 5.9 4.9 7.4 5.1 4.9 1.3 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 CMV_1a PF12467.8 GAM24297.1 - 10 6.5 9.0 40 4.5 9.0 2.0 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family CH PF00307.31 GAM24298.1 - 2.5e-83 275.4 0.5 1.8e-21 76.4 0.0 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_1 PF00036.32 GAM24298.1 - 3.6e-13 48.0 6.4 2e-07 30.1 0.7 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAM24298.1 - 1.5e-11 44.6 2.0 2.7e-11 43.7 1.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GAM24298.1 - 4.9e-11 42.3 3.5 2.3e-10 40.1 1.7 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM24298.1 - 7.7e-11 41.0 3.1 2.3e-05 23.9 0.6 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAM24298.1 - 2.4e-10 39.4 5.9 1.9e-05 24.0 1.0 2.9 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.8 GAM24298.1 - 7.7e-05 22.5 0.0 2 8.3 0.0 3.8 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_9 PF14658.6 GAM24298.1 - 0.008 16.5 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 GAM24298.1 - 0.066 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAM24298.1 - 0.14 12.1 0.4 0.35 10.8 0.4 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Senescence PF06911.12 GAM24299.1 - 0.0024 18.2 0.1 0.0028 18.0 0.1 1.1 1 0 0 1 1 1 1 Senescence-associated protein Coiled PF05710.12 GAM24299.1 - 2.7 8.9 13.0 3.9 8.4 13.0 1.4 1 1 0 1 1 1 0 Coiled coil HiaBD2 PF15403.6 GAM24300.1 - 0.0013 19.1 0.2 0.0018 18.6 0.2 1.3 1 0 0 1 1 1 1 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Coiled PF05710.12 GAM24300.1 - 0.15 12.9 10.3 0.28 12.0 10.3 1.5 1 1 0 1 1 1 0 Coiled coil Big_3_5 PF16640.5 GAM24302.1 - 0.031 14.4 0.8 0.031 14.4 0.8 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) TIG PF01833.24 GAM24304.1 - 0.00041 20.4 20.1 0.0007 19.6 3.5 4.4 3 2 0 3 3 3 3 IPT/TIG domain TPR_19 PF14559.6 GAM24305.1 - 0.065 13.7 0.1 0.21 12.1 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_transf_10 PF00852.19 GAM24306.1 - 8.8e-34 116.8 0.2 1.4e-33 116.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Laminin_G_3 PF13385.6 GAM24306.1 - 2.1e-18 66.9 0.1 6.1e-18 65.4 0.0 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Glyco_tran_10_N PF17039.5 GAM24306.1 - 0.00084 19.8 0.1 0.0024 18.3 0.1 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Sialidase PF02973.16 GAM24306.1 - 0.0061 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Sialidase, N-terminal domain Snf7 PF03357.21 GAM24307.1 - 5.8e-12 45.6 19.7 7.5e-12 45.2 19.3 1.4 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 GAM24307.1 - 0.00019 21.4 6.8 0.00028 20.9 6.8 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF4363 PF14276.6 GAM24307.1 - 1.7 8.8 6.4 7.6 6.7 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) DUF836 PF05768.14 GAM24308.1 - 0.026 14.9 1.0 0.032 14.7 1.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TPR_1 PF00515.28 GAM24309.1 - 5.8e-20 70.2 3.2 0.0016 18.1 0.1 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAM24309.1 - 7.9e-19 66.2 3.3 9.3e-05 22.3 0.0 5.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAM24309.1 - 2.7e-14 52.4 13.8 4.8e-05 23.4 0.5 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM24309.1 - 1e-13 50.7 4.7 0.00091 18.9 0.3 5.3 2 2 3 5 5 5 3 TPR repeat TPR_14 PF13428.6 GAM24309.1 - 5.5e-13 48.6 0.4 0.018 15.8 0.0 5.6 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.6 GAM24309.1 - 1.5e-12 47.6 4.5 0.0039 17.5 0.0 5.9 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM24309.1 - 2.1e-11 44.3 0.4 4.7e-05 24.0 0.1 4.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM24309.1 - 1.3e-09 37.5 3.8 0.11 12.7 0.0 5.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM24309.1 - 1.5e-09 38.2 5.2 0.00058 20.3 0.4 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM24309.1 - 1.2e-08 34.4 1.6 5.3 7.3 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAM24309.1 - 1.1e-05 25.6 6.7 0.0068 16.7 1.0 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM24309.1 - 2e-05 25.0 2.8 4.1 8.2 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM24309.1 - 6.8e-05 22.9 0.1 0.023 14.8 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM24309.1 - 0.00038 20.6 2.5 0.22 11.8 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 GAM24309.1 - 0.0036 17.7 1.7 0.14 12.6 0.2 3.2 3 0 0 3 3 3 1 Bacterial transcriptional activator domain ChAPs PF09295.10 GAM24309.1 - 0.039 13.0 1.2 0.58 9.1 0.1 2.2 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4082 PF13313.6 GAM24309.1 - 0.041 13.9 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) TPR_10 PF13374.6 GAM24309.1 - 0.076 12.9 10.5 10 6.2 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 GAM24309.1 - 0.092 12.8 1.3 53 4.0 0.0 3.8 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 GAM24310.1 - 3.3e-38 126.7 36.3 0.028 14.5 0.6 19.6 20 0 0 20 20 20 9 Tetratricopeptide repeat TPR_14 PF13428.6 GAM24310.1 - 3.5e-34 114.6 13.9 0.038 14.8 0.0 18.6 15 5 5 20 20 19 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAM24310.1 - 1.4e-28 99.2 7.5 5.6e-05 23.7 0.0 12.3 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAM24310.1 - 5.2e-28 95.7 36.6 0.01 15.6 0.7 17.4 19 0 0 19 19 18 7 Tetratricopeptide repeat TPR_8 PF13181.6 GAM24310.1 - 1.2e-26 90.6 41.7 0.061 13.6 0.3 18.2 21 0 0 21 21 16 8 Tetratricopeptide repeat TPR_19 PF14559.6 GAM24310.1 - 2.9e-23 82.2 42.5 1.2e-05 25.7 0.1 15.7 15 3 3 19 19 15 6 Tetratricopeptide repeat TPR_7 PF13176.6 GAM24310.1 - 2.1e-18 64.9 14.0 0.27 11.3 0.0 13.3 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAM24310.1 - 3.9e-17 62.3 44.5 0.0044 17.3 0.5 13.8 11 4 6 17 17 15 8 Tetratricopeptide repeat TPR_17 PF13431.6 GAM24310.1 - 9.5e-16 57.0 30.1 0.057 13.8 0.1 13.7 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM24310.1 - 6.3e-15 54.6 11.3 2.1e-05 24.1 0.3 11.6 13 1 1 14 14 14 3 TPR repeat TPR_6 PF13174.6 GAM24310.1 - 1.6e-10 40.9 41.6 0.18 12.5 0.0 15.5 19 0 0 19 19 15 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM24310.1 - 1.5e-08 34.7 42.3 0.019 15.2 0.1 10.1 11 1 0 11 11 10 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 GAM24310.1 - 2.9e-07 30.5 2.4 2.8 8.2 0.0 8.4 8 2 2 10 10 10 1 Tetratricopeptide repeat BTAD PF03704.17 GAM24310.1 - 0.0031 18.0 11.6 1.8 9.0 0.1 6.0 4 2 0 5 5 5 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 GAM24310.1 - 0.004 17.0 18.4 3.7 7.5 0.0 10.6 12 0 0 12 12 11 1 Tetratricopeptide repeat PPR_2 PF13041.6 GAM24310.1 - 0.0073 16.5 0.3 6.1 7.1 0.2 4.1 4 0 0 4 4 3 1 PPR repeat family TPR_20 PF14561.6 GAM24310.1 - 0.009 16.3 11.7 0.76 10.2 0.0 7.0 7 1 0 7 7 6 1 Tetratricopeptide repeat Thymidylate_kin PF02223.17 GAM24310.1 - 0.015 15.0 0.6 0.068 12.8 0.2 2.3 1 1 1 2 2 2 0 Thymidylate kinase ChAPs PF09295.10 GAM24310.1 - 0.015 14.3 14.4 0.019 14.0 0.9 3.9 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.20 GAM24310.1 - 0.017 15.3 0.0 9 6.8 0.1 4.5 4 0 0 4 4 3 0 PPR repeat Synaptobrevin PF00957.21 GAM24310.1 - 0.064 13.0 0.1 0.32 10.8 0.1 2.3 1 0 0 1 1 1 0 Synaptobrevin DUF2225 PF09986.9 GAM24310.1 - 2.4 7.8 14.6 5.9 6.6 0.2 5.0 4 2 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF4042 PF13251.6 GAM24311.1 - 4.5e-35 121.0 1.3 4.5e-35 121.0 1.3 4.4 5 1 1 6 6 6 1 Domain of unknown function (DUF4042) HEAT PF02985.22 GAM24311.1 - 3.7e-20 70.3 4.8 0.0044 17.1 0.3 9.1 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 GAM24311.1 - 1.6e-14 54.0 0.3 0.033 14.7 0.0 7.7 9 0 0 9 9 9 3 HEAT-like repeat HEAT_2 PF13646.6 GAM24311.1 - 9.9e-13 48.3 0.0 0.00038 20.8 0.0 6.0 3 2 2 5 5 5 4 HEAT repeats Arm PF00514.23 GAM24311.1 - 0.017 15.1 16.6 1.4 9.1 0.0 7.5 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 GAM24311.1 - 0.058 13.4 13.0 0.32 11.0 1.1 5.6 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 LRR_8 PF13855.6 GAM24313.1 - 4.6e-13 48.7 60.2 0.00011 21.8 5.4 8.2 3 2 7 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 GAM24313.1 - 1.7e-08 34.6 64.2 0.00028 21.2 3.1 9.7 6 1 4 10 10 10 7 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 GAM24313.1 - 0.00046 20.4 0.6 0.0013 19.0 0.6 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 GAM24313.1 - 0.0095 16.3 1.4 0.0095 16.3 1.4 11.8 13 2 0 13 13 13 1 Leucine Rich Repeat LRR_9 PF14580.6 GAM24313.1 - 0.62 9.5 7.2 0.081 12.4 1.1 2.6 2 1 0 2 2 2 0 Leucine-rich repeat Cortexin PF11057.8 GAM24313.1 - 1.7 8.6 4.2 1.5 8.7 0.5 2.8 2 0 0 2 2 2 0 Cortexin of kidney Furin-like_2 PF15913.5 GAM24313.1 - 3.9 7.7 10.7 0.088 13.0 3.1 2.0 2 0 0 2 2 2 0 Furin-like repeat, cysteine-rich Actin PF00022.19 GAM24314.1 - 1.3e-113 379.7 0.0 1e-112 376.7 0.0 1.9 1 1 0 1 1 1 1 Actin Arf PF00025.21 GAM24315.1 - 5e-60 201.9 0.0 5.6e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GAM24315.1 - 1.3e-12 47.5 0.2 2.3e-09 36.9 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 GAM24315.1 - 5.7e-10 39.5 0.0 1.2e-09 38.4 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM24315.1 - 7.5e-10 38.5 0.0 9.4e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAM24315.1 - 1.8e-08 34.2 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 GAM24315.1 - 4.7e-07 29.9 0.0 1.4e-06 28.4 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAM24315.1 - 3.2e-05 23.4 0.0 3.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM24315.1 - 0.14 11.7 0.0 6 6.4 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 GAM24315.1 - 0.16 11.7 0.0 0.47 10.2 0.0 1.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Metallophos PF00149.28 GAM24316.1 - 3.7e-39 135.3 0.1 5e-39 134.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 GAM24316.1 - 0.035 13.8 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain AAA_22 PF13401.6 GAM24317.1 - 0.072 13.4 0.1 2 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain CLU PF13236.6 GAM24318.1 - 7.7e-59 199.2 0.0 1.6e-58 198.2 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAM24318.1 - 4e-07 30.2 0.0 4e-07 30.2 0.0 2.6 4 0 0 4 4 4 1 Translation initiation factor eIF3 subunit 135 TPR_17 PF13431.6 GAM24318.1 - 7.6e-07 29.1 1.1 0.05 14.0 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM24318.1 - 0.0025 18.3 0.0 1 9.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM24318.1 - 0.0067 17.2 0.0 0.14 13.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM24318.1 - 0.0093 15.7 5.3 0.19 11.6 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAM24318.1 - 0.011 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_7 PF13176.6 GAM24318.1 - 0.013 15.5 0.2 0.079 13.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM24318.1 - 0.015 15.4 5.1 0.25 11.6 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM24318.1 - 0.043 14.0 0.2 0.2 11.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM24318.1 - 0.2 12.0 1.2 10 6.5 0.2 3.1 1 1 3 4 4 4 0 Tetratricopeptide repeat Cyclin_N PF00134.23 GAM24319.1 - 0.019 14.7 0.2 0.036 13.8 0.2 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain RF-1 PF00472.20 GAM24320.1 - 6.2e-18 64.8 0.1 8.7e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 RF-1 domain Evr1_Alr PF04777.13 GAM24323.1 - 2e-28 98.8 2.2 4.8e-28 97.6 2.2 1.7 1 0 0 1 1 1 1 Erv1 / Alr family Macoilin PF09726.9 GAM24323.1 - 0.12 11.0 3.4 0.12 10.9 3.4 1.0 1 0 0 1 1 1 0 Macoilin family TM2 PF05154.16 GAM24324.1 - 3.2e-21 75.4 10.9 4.4e-21 74.9 10.9 1.2 1 0 0 1 1 1 1 TM2 domain Suf PF05843.14 GAM24324.1 - 6.9 6.6 9.8 8.1 6.3 9.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AAA_33 PF13671.6 GAM24325.1 - 4.8e-12 46.2 0.0 9e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAM24325.1 - 0.0011 19.2 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM24325.1 - 0.0016 18.9 0.0 0.0024 18.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 GAM24325.1 - 0.029 13.9 0.0 0.96 8.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_PrkA PF08298.11 GAM24325.1 - 0.052 12.5 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain Renin_r PF07850.14 GAM24326.1 - 0.0063 17.1 1.3 0.0084 16.7 0.3 1.7 2 0 0 2 2 2 1 Renin receptor-like protein Thr_synth_N PF14821.6 GAM24326.1 - 0.052 13.7 0.1 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 Threonine synthase N terminus DUF4190 PF13828.6 GAM24326.1 - 0.057 13.2 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) SAND PF01342.21 GAM24326.1 - 0.14 11.9 0.6 0.24 11.1 0.6 1.3 1 0 0 1 1 1 0 SAND domain COX16 PF14138.6 GAM24326.1 - 3.9 8.0 7.5 3.1 8.4 0.7 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 BCAS3 PF12490.8 GAM24327.1 - 1.9e-08 34.1 0.8 0.0019 17.8 0.1 2.7 1 1 1 2 2 2 2 Breast carcinoma amplified sequence 3 Dicty_spore_N PF04562.12 GAM24330.1 - 6.6e-08 33.2 21.1 1e-07 32.6 21.1 1.3 1 0 0 1 1 1 1 Dictyostelium spore coat protein, N terminus PHD PF00628.29 GAM24331.1 - 6.4e-16 58.0 27.2 3e-09 36.6 3.7 4.3 3 1 1 4 4 4 2 PHD-finger DUF501 PF04417.12 GAM24331.1 - 0.019 14.8 5.2 0.053 13.3 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF501) MMPL PF03176.15 GAM24331.1 - 0.13 11.2 5.0 0.19 10.6 5.0 1.2 1 0 0 1 1 1 0 MMPL family Tho2 PF11262.8 GAM24331.1 - 4.1 6.5 17.5 0.71 9.0 13.3 1.8 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Presenilin PF01080.17 GAM24331.1 - 6 5.5 22.8 0.13 11.1 10.6 2.2 2 0 0 2 2 2 0 Presenilin LMBR1 PF04791.16 GAM24331.1 - 6.4 5.6 7.1 11 4.8 7.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Indigoidine_A PF04227.12 GAM24333.1 - 1e-125 419.0 5.2 2.1e-125 417.9 5.2 1.6 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 GAM24333.1 - 6.2e-35 120.9 0.2 1.1e-34 120.2 0.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Pox_MCEL PF03291.16 GAM24334.1 - 7.3e-78 262.0 0.2 1.3e-77 261.1 0.2 1.3 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 GAM24334.1 - 2.2e-07 31.5 0.0 6.6e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM24334.1 - 9.3e-05 23.0 0.0 0.0002 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM24334.1 - 0.0055 16.1 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAM24334.1 - 0.0068 17.1 0.0 0.0068 17.1 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase domain TFIIA PF03153.13 GAM24334.1 - 0.016 15.2 19.3 0.021 14.8 19.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NNMT_PNMT_TEMT PF01234.17 GAM24334.1 - 0.037 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Pkinase PF00069.25 GAM24335.1 - 3.1e-68 230.0 1.8 3.5e-68 229.8 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24335.1 - 6.5e-39 133.8 0.1 1.3e-38 132.8 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM24335.1 - 5.4e-08 32.5 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM24335.1 - 0.0006 19.2 0.1 0.0014 18.0 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM24335.1 - 0.0029 17.6 0.0 0.2 11.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family PT-TG PF14449.6 GAM24335.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Pre-toxin TG PPP4R2 PF09184.11 GAM24335.1 - 0.18 11.4 16.7 0.023 14.3 10.0 2.1 2 0 0 2 2 2 0 PPP4R2 FTA2 PF13095.6 GAM24335.1 - 0.2 11.3 0.1 0.2 11.3 0.1 2.5 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DNA_pol_phi PF04931.13 GAM24335.1 - 1.2 7.2 12.0 1.9 6.5 12.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 GAM24335.1 - 3.8 7.8 7.4 11 6.3 7.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TFIIA PF03153.13 GAM24335.1 - 5 7.0 34.4 3.9 7.4 12.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 GAM24335.1 - 5.9 6.9 15.2 0.23 11.5 7.0 2.5 3 0 0 3 3 3 0 RXT2-like, N-terminal COQ7 PF03232.13 GAM24336.1 - 2.4e-69 232.5 0.1 3.1e-69 232.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 GAM24336.1 - 2.5e-06 27.9 0.1 5.4e-06 26.9 0.1 1.5 1 1 0 1 1 1 1 Rubrerythrin Avl9 PF09794.9 GAM24336.1 - 0.0016 17.2 0.7 0.0028 16.4 0.7 1.3 1 0 0 1 1 1 1 Transport protein Avl9 Ferritin_2 PF13668.6 GAM24336.1 - 0.017 15.3 0.4 0.85 9.8 0.0 2.2 1 1 1 2 2 2 0 Ferritin-like domain NTP_transferase PF00483.23 GAM24336.1 - 0.031 13.8 0.1 0.031 13.8 0.1 1.4 2 0 0 2 2 2 0 Nucleotidyl transferase TIG PF01833.24 GAM24337.1 - 2.2e-22 78.9 61.9 2e-07 31.0 6.0 7.6 8 0 0 8 8 8 5 IPT/TIG domain Lectin_C PF00059.21 GAM24337.1 - 3.1e-05 24.7 0.0 9.6e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Lectin C-type domain EGF_2 PF07974.13 GAM24337.1 - 0.00072 19.9 12.5 0.002 18.5 12.5 1.8 1 0 0 1 1 1 1 EGF-like domain LapA_dom PF06305.11 GAM24337.1 - 0.011 15.5 0.4 0.027 14.3 0.4 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM154 PF15102.6 GAM24337.1 - 0.13 12.2 2.4 0.16 11.9 1.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family I-EGF_1 PF18372.1 GAM24337.1 - 0.29 11.2 7.7 1.1 9.4 7.7 2.1 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Glycos_transf_2 PF00535.26 GAM24338.1 - 1.3e-36 126.0 0.0 1.5e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAM24338.1 - 1.7e-13 51.0 0.0 2.1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAM24338.1 - 4.1e-05 23.1 0.0 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 GAM24338.1 - 0.0013 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7N PF13733.6 GAM24338.1 - 0.022 14.4 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 adh_short PF00106.25 GAM24339.1 - 3.4e-46 157.2 0.1 5.2e-46 156.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM24339.1 - 1.6e-33 116.2 0.1 2.2e-33 115.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM24339.1 - 4.5e-11 43.0 0.2 6.6e-11 42.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM24339.1 - 0.00011 21.7 0.2 0.00051 19.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM24339.1 - 0.00013 21.2 0.1 0.00021 20.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 GAM24339.1 - 0.0071 15.8 0.0 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.15 GAM24339.1 - 0.12 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F-box PF00646.33 GAM24340.1 - 1.2e-06 28.2 0.1 1.4e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM24340.1 - 0.022 14.6 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 F-box-like M-factor PF03855.13 GAM24340.1 - 0.22 11.7 3.8 0.33 11.1 3.8 1.3 1 0 0 1 1 1 0 M-factor Pyr_redox_2 PF07992.14 GAM24342.1 - 5.1e-44 150.7 0.0 9.2e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 GAM24342.1 - 2.4e-09 36.1 1.2 0.00079 18.8 0.3 2.7 2 0 0 2 2 2 2 EF hand Pyr_redox PF00070.27 GAM24342.1 - 9e-08 32.6 0.0 4.1e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 GAM24342.1 - 2.2e-07 31.2 0.1 0.034 14.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM24342.1 - 4.4e-07 29.3 4.5 0.015 15.2 0.3 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 GAM24342.1 - 1.5e-05 24.2 3.8 0.063 12.8 0.1 2.7 2 0 0 2 2 2 2 EF hand IMUP PF15761.5 GAM24342.1 - 0.0048 17.6 2.2 0.0086 16.8 2.2 1.3 1 0 0 1 1 1 1 Immortalisation up-regulated protein EspB_PE PF18625.1 GAM24342.1 - 0.082 13.4 0.3 0.19 12.2 0.3 1.6 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain EF-hand_8 PF13833.6 GAM24342.1 - 0.17 11.8 1.2 1.6 8.6 0.2 2.5 2 0 0 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM24342.1 - 0.17 12.2 1.1 1.5 9.2 1.1 2.2 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Ldh_1_N PF00056.23 GAM24343.1 - 5.2e-34 117.3 0.3 9.5e-34 116.5 0.3 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 GAM24343.1 - 7.4e-34 117.1 0.0 2.2e-33 115.6 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sec1 PF00995.23 GAM24344.1 - 3.7e-131 439.2 8.5 4.2e-131 439.0 8.5 1.0 1 0 0 1 1 1 1 Sec1 family Rotavirus_VP7 PF05868.11 GAM24344.1 - 0.05 13.0 1.4 0.069 12.5 0.1 1.8 2 0 0 2 2 2 0 Rotavirus major outer capsid protein VP7 V-ATPase_H_C PF11698.8 GAM24344.1 - 0.066 13.3 0.9 0.21 11.7 0.9 1.8 1 0 0 1 1 1 0 V-ATPase subunit H B12-binding PF02310.19 GAM24344.1 - 0.075 13.1 0.0 0.61 10.1 0.0 2.3 1 1 1 2 2 2 0 B12 binding domain NOG1_N PF17835.1 GAM24344.1 - 0.28 11.1 4.0 29 4.6 0.1 3.5 2 1 1 3 3 3 0 NOG1 N-terminal helical domain Pkinase_Tyr PF07714.17 GAM24346.1 - 1.6e-69 234.1 0.0 2.8e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM24346.1 - 2.3e-64 217.3 0.0 3.8e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 GAM24346.1 - 4.5e-05 22.6 0.8 0.0021 17.0 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 GAM24346.1 - 0.00017 21.0 0.0 0.00074 18.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like NLPC_P60 PF00877.19 GAM24347.1 - 1.5e-12 47.4 0.6 2e-12 47.1 0.6 1.2 1 0 0 1 1 1 1 NlpC/P60 family DUF1175 PF06672.11 GAM24347.1 - 0.04 13.6 0.0 0.16 11.6 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) MCM PF00493.23 GAM24348.1 - 2e-95 318.2 0.0 3e-95 317.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAM24348.1 - 2.1e-33 114.8 0.3 3.8e-33 114.0 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAM24348.1 - 8.4e-24 83.8 0.5 2.7e-23 82.2 0.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 GAM24348.1 - 2.9e-08 33.4 0.0 3.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 GAM24348.1 - 0.00052 20.6 0.3 0.002 18.7 0.3 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Sigma54_activat PF00158.26 GAM24348.1 - 0.0012 18.5 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 GAM24348.1 - 0.0015 18.4 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM24348.1 - 0.028 14.4 0.0 0.093 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Macoilin PF09726.9 GAM24348.1 - 0.78 8.2 11.2 1.2 7.7 11.2 1.2 1 0 0 1 1 1 0 Macoilin family DUF4196 PF13846.6 GAM24348.1 - 8.1 6.7 18.8 0.45 10.7 12.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) SLC12 PF03522.15 GAM24348.1 - 9.6 5.1 12.9 18 4.2 12.9 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Sulfate_transp PF00916.20 GAM24350.1 - 6.9e-98 327.9 31.9 9.9e-98 327.4 31.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAM24350.1 - 1.1e-07 31.5 0.0 2.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAM24350.1 - 0.0045 17.4 7.6 0.0045 17.4 7.6 3.5 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily tRNA-synt_1d PF00750.19 GAM24351.1 - 5.8e-103 344.5 3.1 7.4e-103 344.1 3.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAM24351.1 - 2.3e-25 89.1 0.2 5e-25 88.0 0.2 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 GAM24351.1 - 3.9e-08 33.8 1.2 8.4e-08 32.7 0.3 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 GAM24351.1 - 0.063 12.6 0.1 0.18 11.1 0.0 1.8 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain CAP PF00188.26 GAM24353.1 - 1.2e-09 39.1 1.4 1.3e-09 38.9 0.2 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family SSP160 PF06933.11 GAM24353.1 - 0.15 10.2 4.5 0.22 9.7 4.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 GAM24353.1 - 0.24 11.4 5.6 0.52 10.3 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FNIP PF05725.12 GAM24354.1 - 5.1e-35 119.4 25.4 1.1e-12 47.9 0.0 8.3 5 3 3 8 8 8 7 FNIP Repeat GST_N_3 PF13417.6 GAM24355.1 - 2.3e-11 43.9 0.0 4.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM24355.1 - 4e-10 39.9 0.0 9.9e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM24355.1 - 1.1e-09 38.4 0.0 2.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM24355.1 - 1.1e-08 35.1 0.1 1.8e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM24355.1 - 1.4e-06 28.4 0.1 2.1e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM24355.1 - 7.6e-05 22.7 0.1 0.00016 21.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NMO PF03060.15 GAM24356.1 - 4.9e-39 134.6 0.0 3.7e-37 128.5 0.0 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 GAM24356.1 - 2.2e-05 23.8 0.1 3.4e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 GAM24356.1 - 0.00019 20.6 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 GAM24356.1 - 0.00072 19.1 0.0 0.002 17.6 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein IMPDH PF00478.25 GAM24356.1 - 0.0015 17.6 0.3 0.0021 17.1 0.3 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Trp_syntA PF00290.20 GAM24356.1 - 0.0097 14.8 0.1 0.046 12.6 0.1 1.8 2 0 0 2 2 2 1 Tryptophan synthase alpha chain DUF561 PF04481.12 GAM24356.1 - 0.03 13.5 0.2 0.042 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) G3P_antiterm PF04309.12 GAM24356.1 - 0.16 11.4 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Stm1_N PF09598.10 GAM24358.1 - 0.012 16.5 0.4 0.05 14.5 0.4 1.9 1 1 0 1 1 1 0 Stm1 AMP-binding PF00501.28 GAM24359.1 - 2.4e-86 290.0 0.0 2.9e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GAM24359.1 - 6.5e-21 74.0 1.9 9.8e-21 73.4 1.0 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 GAM24359.1 - 1.6e-20 73.8 0.1 5e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1967 PF09269.11 GAM24359.1 - 0.099 12.6 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Elongin_A PF06881.11 GAM24360.1 - 1.1e-17 64.4 0.2 1.8e-17 63.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ATP11 PF06644.11 GAM24360.1 - 0.0029 17.4 2.5 0.0039 17.0 2.5 1.1 1 0 0 1 1 1 1 ATP11 protein bacHORMA_1 PF18138.1 GAM24360.1 - 0.019 14.9 1.2 0.024 14.5 1.2 1.2 1 0 0 1 1 1 0 Bacterial HORMA domain family 1 DUF684 PF05075.14 GAM24360.1 - 0.11 11.5 1.7 0.18 10.7 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF684) Exonuc_VII_L PF02601.15 GAM24361.1 - 0.065 12.8 5.7 0.085 12.4 5.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BORG_CEP PF14957.6 GAM24361.1 - 0.21 12.8 6.3 0.34 12.1 6.3 1.2 1 0 0 1 1 1 0 Cdc42 effector VIT1 PF01988.19 GAM24361.1 - 0.24 11.3 0.4 0.63 9.9 0.4 1.8 1 0 0 1 1 1 0 VIT family EPL1 PF10513.9 GAM24361.1 - 0.29 11.5 12.0 0.49 10.8 12.0 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like PTPRCAP PF15713.5 GAM24361.1 - 0.79 10.0 13.5 1.3 9.3 13.5 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Borrelia_P83 PF05262.11 GAM24361.1 - 0.83 8.1 11.4 1.1 7.6 11.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIA PF03153.13 GAM24361.1 - 3.2 7.7 25.4 4.3 7.2 25.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 GAM24361.1 - 6.1 5.5 8.2 11 4.7 8.2 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Hydin_ADK PF17213.3 GAM24361.1 - 7.6 6.8 8.6 12 6.2 8.6 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF2370 PF10176.9 GAM24361.1 - 8.9 5.9 0.0 8.9 5.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2370) SLBP_RNA_bind PF15247.6 GAM24362.1 - 1.3e-28 98.9 1.4 1.3e-28 98.9 1.4 2.6 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain La PF05383.17 GAM24363.1 - 1.8e-15 56.7 0.0 4.9e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 La domain DUF2724 PF10893.8 GAM24363.1 - 0.059 13.2 0.2 0.059 13.2 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2724) SCVP PF17619.2 GAM24363.1 - 1.7 9.5 6.8 1.1 10.1 0.4 3.5 2 0 0 2 2 2 0 Secreted clade V proteins Thioredoxin PF00085.20 GAM24364.1 - 1e-19 70.4 0.0 1.2e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 GAM24364.1 - 0.00017 21.4 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 GAM24364.1 - 0.00051 20.2 0.0 0.0007 19.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 GAM24364.1 - 0.00098 18.9 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAM24364.1 - 0.0036 17.2 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 GAM24364.1 - 0.0041 17.4 0.0 0.0093 16.3 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GAM24364.1 - 0.012 16.1 0.1 0.074 13.5 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain OST3_OST6 PF04756.13 GAM24364.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family ADH_N_2 PF16884.5 GAM24365.1 - 5.2e-30 103.5 0.0 8.9e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 GAM24365.1 - 2.8e-21 75.9 0.0 4.3e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAM24365.1 - 7e-12 46.5 0.0 1.4e-11 45.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RecA PF00154.21 GAM24366.1 - 1.4e-130 434.5 0.2 1.8e-130 434.1 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 GAM24366.1 - 1.8e-14 53.6 0.1 7.1e-14 51.7 0.1 1.8 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 GAM24366.1 - 4.7e-09 35.9 1.1 5.2e-07 29.3 0.5 3.3 2 1 0 2 2 2 1 KaiC AAA_22 PF13401.6 GAM24366.1 - 0.00097 19.4 0.2 0.014 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 GAM24366.1 - 0.0016 18.4 2.1 0.0033 17.4 0.0 2.4 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA PF00004.29 GAM24366.1 - 0.0017 18.8 1.3 0.0076 16.7 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAM24366.1 - 0.0023 17.7 0.5 0.005 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAM24366.1 - 0.0069 16.0 1.6 0.016 14.8 0.3 2.2 2 1 0 2 2 2 1 AAA domain CobU PF02283.16 GAM24366.1 - 0.0093 15.5 0.0 0.024 14.2 0.0 1.7 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase ABC_tran PF00005.27 GAM24366.1 - 0.02 15.4 1.6 0.04 14.4 0.0 2.3 3 0 0 3 3 3 0 ABC transporter AAA_16 PF13191.6 GAM24366.1 - 0.052 13.9 0.2 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain TK PF00265.18 GAM24366.1 - 0.054 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase AAA_14 PF13173.6 GAM24366.1 - 0.088 12.8 0.1 0.46 10.5 0.0 2.3 2 1 1 3 3 3 0 AAA domain WD40 PF00400.32 GAM24368.1 - 2.1e-26 91.6 3.2 9e-09 35.8 0.4 6.6 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM24368.1 - 7.6e-21 74.2 0.3 0.0017 18.6 0.0 6.4 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM24368.1 - 4.2e-07 30.0 0.2 0.00032 20.6 0.0 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAM24368.1 - 0.00039 19.2 0.8 0.0022 16.7 0.1 2.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 GAM24368.1 - 0.00064 19.1 0.0 0.78 9.0 0.1 3.0 2 1 1 3 3 3 2 WD40-like domain IKI3 PF04762.12 GAM24368.1 - 0.0027 15.8 0.2 0.026 12.6 0.2 2.2 2 0 0 2 2 2 1 IKI3 family CDK2AP PF09806.9 GAM24368.1 - 0.0032 17.6 3.0 0.0054 16.8 3.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein PD40 PF07676.12 GAM24368.1 - 0.0033 17.3 0.1 0.42 10.6 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat SR-25 PF10500.9 GAM24368.1 - 0.51 9.9 9.0 0.75 9.4 9.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF508 PF04370.12 GAM24368.1 - 1.3 8.8 5.1 2.3 7.9 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Herpes_capsid PF06112.11 GAM24368.1 - 8 6.5 27.4 14 5.7 27.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SSP160 PF06933.11 GAM24369.1 - 0.0058 14.9 2.6 0.0055 15.0 2.6 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Med3 PF11593.8 GAM24369.1 - 0.28 10.4 6.0 0.25 10.5 6.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Endotoxin_N PF03945.14 GAM24370.1 - 3.4e-41 141.4 3.0 5.6e-41 140.7 3.0 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Med2 PF11214.8 GAM24370.1 - 0.2 11.8 3.9 1.1 9.4 0.3 2.8 3 0 0 3 3 3 0 Mediator complex subunit 2 KRBA1 PF15287.6 GAM24371.1 - 0.16 11.7 0.1 0.16 11.7 0.1 3.9 4 0 0 4 4 4 0 KRBA1 family repeat F-box-like PF12937.7 GAM24372.1 - 3.1e-06 27.0 0.4 3.1e-06 27.0 0.4 2.3 2 1 0 2 2 2 1 F-box-like BTK PF00779.19 GAM24372.1 - 8.9e-05 22.2 0.7 0.00022 21.0 0.7 1.7 1 0 0 1 1 1 1 BTK motif F-box PF00646.33 GAM24372.1 - 0.00044 20.1 0.1 0.0015 18.3 0.1 2.0 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 GAM24372.1 - 0.00086 19.8 0.2 0.0016 19.0 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A RNA_polI_A34 PF08208.11 GAM24373.1 - 4.8e-14 52.9 116.2 2.2e-09 37.7 71.2 3.2 1 1 2 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 CDC27 PF09507.10 GAM24373.1 - 0.074 12.4 84.6 0.097 12.0 84.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RIFIN PF02009.16 GAM24374.1 - 0.0034 17.3 0.5 0.0058 16.6 0.5 1.4 1 0 0 1 1 1 1 Rifin PRR18 PF15671.5 GAM24374.1 - 0.11 12.3 17.5 0.21 11.5 14.2 2.3 2 0 0 2 2 2 0 Proline-rich protein family 18 TMEM154 PF15102.6 GAM24374.1 - 5.5 6.9 11.3 10 6.0 11.3 1.4 1 0 0 1 1 1 0 TMEM154 protein family UPF1_Zn_bind PF09416.10 GAM24375.1 - 5.5e-66 221.2 3.9 1.3e-65 220.0 3.9 1.7 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 GAM24375.1 - 3.3e-59 199.9 0.0 6.1e-59 199.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM24375.1 - 2e-45 155.7 10.3 5.3e-27 95.3 0.1 3.2 2 1 1 3 3 3 2 AAA domain DUF5599 PF18141.1 GAM24375.1 - 5.8e-25 87.3 0.1 1.5e-24 86.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 GAM24375.1 - 2.9e-12 46.7 0.0 3.7e-11 43.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM24375.1 - 1.4e-10 41.7 0.3 6.5e-10 39.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 GAM24375.1 - 0.0029 17.4 0.1 0.0059 16.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 GAM24375.1 - 0.0093 15.2 6.0 0.014 14.6 0.0 3.0 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 GAM24375.1 - 0.0095 15.1 0.0 0.51 9.4 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase ResIII PF04851.15 GAM24375.1 - 0.012 15.6 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 GAM24375.1 - 0.038 13.4 0.0 0.091 12.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 GAM24375.1 - 0.045 13.7 0.1 0.088 12.8 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain ATPase PF06745.13 GAM24375.1 - 0.046 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF3126 PF11324.8 GAM24375.1 - 0.09 12.6 0.0 0.63 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3126) Rad17 PF03215.15 GAM24375.1 - 0.091 12.7 0.5 0.23 11.4 0.1 1.9 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_22 PF13401.6 GAM24375.1 - 0.093 13.0 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAM24375.1 - 0.13 12.8 0.2 0.99 10.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 GAM24375.1 - 0.15 12.1 0.1 1 9.3 0.0 2.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 GAM24375.1 - 0.16 12.4 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 GAM24375.1 - 0.26 11.1 0.7 0.51 10.2 0.0 1.9 2 0 0 2 2 1 0 Helicase Zip PF02535.22 GAM24375.1 - 7.9 5.6 6.3 13 4.9 6.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Erf4 PF10256.9 GAM24376.1 - 0.017 15.2 0.2 0.023 14.8 0.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family zf-C2H2 PF00096.26 GAM24378.1 - 1 10.0 3.8 0.68 10.5 0.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type PGP_phosphatase PF09419.10 GAM24379.1 - 5.9e-43 146.4 0.0 7.6e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase PF00702.26 GAM24379.1 - 5.2e-07 30.2 0.0 0.0026 18.1 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAM24379.1 - 6.7e-07 29.3 0.0 1.4e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 GAM24379.1 - 0.0019 18.3 0.0 0.018 15.1 0.0 2.1 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase PCI PF01399.27 GAM24380.1 - 3.6e-16 59.6 0.2 9.4e-16 58.2 0.2 1.8 1 0 0 1 1 1 1 PCI domain WD40 PF00400.32 GAM24381.1 - 2.7e-12 47.0 10.6 7.1e-05 23.5 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat F-box-like PF12937.7 GAM24381.1 - 5.8e-10 38.9 0.4 1.6e-09 37.5 0.1 2.0 2 0 0 2 2 2 1 F-box-like START PF01852.19 GAM24381.1 - 2.2e-07 30.5 0.1 7e-06 25.6 0.0 2.6 3 0 0 3 3 3 1 START domain F-box PF00646.33 GAM24381.1 - 6e-06 26.0 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAM24381.1 - 0.00092 19.1 0.0 0.0028 17.5 0.0 1.8 1 0 0 1 1 1 1 F-box Glyoxalase PF00903.25 GAM24382.1 - 5.5e-22 78.3 1.2 5.1e-16 59.0 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAM24382.1 - 6e-10 39.4 0.1 0.0012 19.1 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 GAM24382.1 - 2e-05 24.8 0.1 0.00011 22.3 0.1 1.9 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 GAM24382.1 - 4.3e-05 23.7 0.1 0.35 11.0 0.0 4.1 4 1 0 4 4 4 2 Glyoxalase-like domain DNA_primase_S PF01896.19 GAM24382.1 - 0.022 14.8 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 DNA primase small subunit CDK2AP PF09806.9 GAM24384.1 - 3.6 7.6 8.4 0.64 10.0 1.2 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein GATA PF00320.27 GAM24386.1 - 1.2e-16 60.0 5.9 1.2e-16 60.0 5.9 1.9 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAM24386.1 - 0.16 11.5 2.3 0.34 10.5 2.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Senescence PF06911.12 GAM24386.1 - 0.52 10.6 5.8 0.15 12.3 1.8 2.0 2 0 0 2 2 2 0 Senescence-associated protein DUF4407 PF14362.6 GAM24386.1 - 2.3 7.5 14.3 2.1 7.7 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NLPC_P60 PF00877.19 GAM24387.1 - 1.1e-11 44.7 0.1 1.1e-11 44.7 0.1 1.6 2 0 0 2 2 2 1 NlpC/P60 family DUF1175 PF06672.11 GAM24387.1 - 0.028 14.1 0.3 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1175) DUF5397 PF17375.2 GAM24387.1 - 0.13 12.0 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5397) Ibs_toxin PF13956.6 GAM24387.1 - 6.4 6.9 6.1 11 6.2 6.1 1.3 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system AAA_6 PF12774.7 GAM24388.1 - 2.4e-134 447.5 0.0 1.3e-133 445.0 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 GAM24388.1 - 4.1e-115 385.6 11.9 4.1e-115 385.6 11.9 3.9 5 1 0 5 5 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 GAM24388.1 - 2e-112 376.2 13.6 2e-112 376.2 13.6 5.8 8 0 0 8 8 7 2 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 GAM24388.1 - 2.7e-73 245.7 0.0 2.7e-73 245.7 0.0 4.8 6 0 0 6 6 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 GAM24388.1 - 3.8e-71 239.5 0.0 2.8e-70 236.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 GAM24388.1 - 3e-51 174.5 5.2 3.1e-51 174.4 1.9 2.9 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 GAM24388.1 - 5.2e-45 153.2 0.0 8.8e-37 126.4 0.0 4.5 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 GAM24388.1 - 1.5e-42 145.9 14.8 3.2e-42 144.8 14.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 GAM24388.1 - 6.1e-38 130.2 0.0 2.8e-37 128.0 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 GAM24388.1 - 4.3e-33 114.2 0.0 1.4e-13 51.0 0.0 6.1 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 GAM24388.1 - 5.4e-28 97.5 0.0 8.5e-27 93.6 0.0 3.3 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 GAM24388.1 - 4.8e-21 75.2 0.0 3.9e-20 72.3 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 GAM24388.1 - 2.3e-14 53.8 0.1 0.0014 19.0 0.0 6.2 6 0 0 6 6 5 4 AAA domain AAA PF00004.29 GAM24388.1 - 1.1e-12 48.5 0.0 0.0012 19.3 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM24388.1 - 1e-08 35.8 0.1 1 9.7 0.0 7.1 7 0 0 7 7 6 1 AAA ATPase domain AAA_33 PF13671.6 GAM24388.1 - 1.2e-08 35.2 0.0 0.17 12.1 0.0 5.1 4 0 0 4 4 4 2 AAA domain AAA_lid_1 PF17857.1 GAM24388.1 - 1.5e-08 34.7 0.0 7.7e-08 32.5 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain Rad17 PF03215.15 GAM24388.1 - 0.0002 21.4 0.7 3.7 7.4 0.0 4.9 5 0 0 5 5 4 1 Rad17 P-loop domain AAA_30 PF13604.6 GAM24388.1 - 0.00027 20.7 0.1 5.5 6.7 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAM24388.1 - 0.00054 19.7 0.0 2.5 7.9 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_19 PF13245.6 GAM24388.1 - 0.00064 20.1 0.4 0.24 11.7 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 GAM24388.1 - 0.0017 18.9 4.4 19 5.8 0.0 5.9 6 0 0 6 6 5 0 AAA domain T2SSE PF00437.20 GAM24388.1 - 0.0019 17.3 0.0 0.15 11.1 0.0 2.9 3 0 0 3 3 2 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 GAM24388.1 - 0.0029 17.0 2.8 0.7 9.2 0.0 3.5 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAM24388.1 - 0.0037 17.0 0.6 1.7 8.3 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 GAM24388.1 - 0.0061 16.3 0.0 18 5.0 0.0 4.7 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 GAM24388.1 - 0.0085 15.5 0.0 17 4.6 0.0 4.5 4 0 0 4 4 4 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 GAM24388.1 - 0.027 14.8 0.1 76 3.8 0.0 4.4 4 0 0 4 4 3 0 RNA helicase AAA_25 PF13481.6 GAM24388.1 - 0.061 12.9 0.0 0.38 10.3 0.0 2.4 1 0 0 1 1 1 0 AAA domain UPF0489 PF12640.7 GAM24388.1 - 0.094 12.9 2.1 0.25 11.5 0.7 2.4 2 0 0 2 2 2 0 UPF0489 domain Plasmid_RAQPRD PF09686.10 GAM24388.1 - 7.6 6.8 6.9 28 5.0 0.0 4.6 3 0 0 3 3 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) MMS1_N PF10433.9 GAM24389.1 - 6e-41 140.6 9.4 6e-41 140.6 9.4 2.2 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAM24389.1 - 2e-15 57.0 3.3 2.5e-15 56.6 1.2 2.3 4 0 0 4 4 4 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 GAM24389.1 - 0.0063 16.8 0.0 20 5.5 0.0 4.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Frizzled PF01534.17 GAM24390.1 - 4.1e-15 55.7 18.1 6.1e-15 55.1 18.1 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 GAM24390.1 - 3.8e-05 24.3 4.9 3.8e-05 24.3 4.9 1.7 2 0 0 2 2 2 1 Fz domain 7tm_1 PF00001.21 GAM24390.1 - 0.0014 18.0 13.3 0.0022 17.4 11.8 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Cas9_a PF18470.1 GAM24390.1 - 0.16 11.5 0.4 0.27 10.7 0.4 1.2 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain PHO4 PF01384.20 GAM24390.1 - 1.5 7.8 7.0 0.31 10.0 3.2 1.8 1 1 1 2 2 2 0 Phosphate transporter family Isochorismatase PF00857.20 GAM24391.1 - 1.3e-25 90.5 1.5 3.3e-25 89.3 1.5 1.5 1 1 0 1 1 1 1 Isochorismatase family Mito_carr PF00153.27 GAM24392.1 - 1.8e-70 232.9 2.1 9.4e-27 92.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein VKOR PF07884.14 GAM24392.1 - 0.058 13.6 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Vitamin K epoxide reductase family Nramp PF01566.18 GAM24393.1 - 5.6e-124 413.7 12.2 5.6e-124 413.7 12.2 1.9 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein RWP-RK PF02042.15 GAM24394.1 - 2.8e-06 27.2 0.2 7.8e-06 25.8 0.2 1.8 1 0 0 1 1 1 1 RWP-RK domain Stealth_CR4 PF17103.5 GAM24394.1 - 0.08 12.8 1.8 0.24 11.3 0.9 2.2 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 DUF1232 PF06803.12 GAM24395.1 - 0.03 14.1 0.2 0.048 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) FAD_binding_7 PF03441.14 GAM24395.1 - 0.065 12.7 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase PhyH PF05721.13 GAM24396.1 - 1.2e-49 169.5 0.0 1.4e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Mito_carr PF00153.27 GAM24397.1 - 1.5e-64 213.9 2.5 3e-20 71.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.25 GAM24398.1 - 1.1e-16 61.1 0.1 1.4e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM24398.1 - 1.2e-08 35.2 0.1 2.2e-08 34.4 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM24398.1 - 2.6e-07 30.6 0.0 3.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM24398.1 - 1.7e-05 24.7 0.0 4.8e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 GAM24398.1 - 0.00013 22.6 0.0 0.00016 22.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM24398.1 - 0.0031 17.7 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 GAM24398.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_15 PF17013.5 GAM24398.1 - 0.096 12.1 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase cNMP_binding PF00027.29 GAM24399.1 - 2.3e-26 91.7 0.1 8e-12 45.1 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 GAM24399.1 - 3e-08 33.4 0.1 5.5e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAM24399.1 - 4e-06 27.0 0.3 7.8e-06 26.0 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 GAM24399.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain VPS9 PF02204.18 GAM24400.1 - 3.2e-13 49.8 0.0 1.4e-12 47.7 0.0 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 GAM24400.1 - 1.8e-06 27.8 0.9 8.4e-06 25.6 0.9 2.1 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DASH_Spc19 PF08287.11 GAM24400.1 - 3.3 7.6 8.2 3.8 7.4 0.4 3.0 3 0 0 3 3 3 0 Spc19 VPS9 PF02204.18 GAM24401.1 - 6.9e-11 42.3 0.4 3.7e-10 39.9 0.0 2.5 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Tektin PF03148.14 GAM24401.1 - 0.019 13.7 0.7 0.029 13.1 0.7 1.2 1 0 0 1 1 1 0 Tektin family Mob1_phocein PF03637.17 GAM24403.1 - 2.3e-79 265.3 0.2 2.7e-79 265.1 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family zf-B_box PF00643.24 GAM24404.1 - 7.8e-09 35.6 6.5 1.4e-08 34.7 6.5 1.3 1 0 0 1 1 1 1 B-box zinc finger Dynactin_p22 PF07426.11 GAM24404.1 - 0.00097 19.0 1.7 0.0091 15.9 0.2 2.2 1 1 1 2 2 2 1 Dynactin subunit p22 Csm2_III-A PF03750.13 GAM24404.1 - 0.0015 19.3 1.4 0.0045 17.8 1.2 1.7 1 1 1 2 2 2 1 Csm2 Type III-A RPW8 PF05659.11 GAM24404.1 - 0.0039 16.9 0.8 0.016 14.9 0.3 2.0 1 1 1 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Sec20 PF03908.13 GAM24404.1 - 0.0096 15.8 0.3 0.025 14.5 0.3 1.7 1 0 0 1 1 1 1 Sec20 CEBP_ZZ PF16366.5 GAM24404.1 - 0.25 11.6 4.5 0.46 10.7 4.5 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 GAM24404.1 - 0.51 10.6 4.6 1.1 9.5 4.6 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ribosomal_S19 PF00203.21 GAM24406.1 - 4e-33 113.1 0.3 5.8e-33 112.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Nup84_Nup100 PF04121.13 GAM24407.1 - 6.4e-166 553.5 19.5 8.9e-166 553.1 19.5 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 NDUF_B7 PF05676.13 GAM24407.1 - 0.053 13.2 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CH PF00307.31 GAM24408.1 - 1.2e-40 138.0 8.3 1.7e-16 60.4 0.4 5.3 6 0 0 6 6 6 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM24408.1 - 1.7e-05 24.6 0.4 0.0016 18.2 0.2 3.1 2 0 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.11 GAM24408.1 - 0.00044 20.3 0.1 0.011 15.8 0.1 3.1 2 0 0 2 2 2 1 CH-like domain in sperm protein SAM_2 PF07647.17 GAM24408.1 - 0.12 12.5 2.5 2 8.6 0.1 2.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DASH_Dam1 PF08653.10 GAM24408.1 - 0.34 10.7 3.4 2.4 8.0 0.4 3.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 zf-C3HC4 PF00097.25 GAM24409.1 - 1.4e-05 24.9 21.1 1.4e-05 24.9 21.1 3.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM24409.1 - 8.2e-05 22.5 18.3 8.2e-05 22.5 18.3 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAM24409.1 - 0.00031 20.5 21.5 0.00031 20.5 21.5 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM24409.1 - 0.0017 18.3 18.9 0.0017 18.3 18.9 3.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAM24409.1 - 0.0024 17.7 17.7 0.0024 17.7 17.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAM24409.1 - 0.003 17.7 21.8 0.003 17.7 21.8 3.0 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GAM24409.1 - 0.0096 16.2 20.3 0.0096 16.2 20.3 3.4 2 1 0 2 2 2 1 Ring finger domain Profilin PF00235.19 GAM24410.1 - 6.6e-41 139.5 0.3 7.4e-41 139.4 0.3 1.0 1 0 0 1 1 1 1 Profilin GSAP-16 PF14959.6 GAM24411.1 - 2.9e-22 78.6 1.1 8.1e-22 77.2 0.4 2.1 2 0 0 2 2 2 1 gamma-Secretase-activating protein C-term RWP-RK PF02042.15 GAM24412.1 - 1.1e-24 86.2 0.1 1.9e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain GREB1 PF15782.5 GAM24412.1 - 0.063 10.4 13.5 0.077 10.1 13.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HTH_17 PF12728.7 GAM24412.1 - 0.084 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PAT1 PF09770.9 GAM24412.1 - 0.94 7.7 24.9 1.4 7.1 24.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 GAM24412.1 - 5.7 5.6 11.0 7.2 5.3 11.0 1.2 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 GAM24412.1 - 6 5.6 11.6 8.1 5.1 11.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DivIC PF04977.15 GAM24412.1 - 6.8 6.5 17.2 1.4 8.8 0.4 2.4 2 0 0 2 2 2 0 Septum formation initiator EGF_2 PF07974.13 GAM24415.1 - 3.6e-05 24.1 7.3 6.6e-05 23.2 7.3 1.5 1 0 0 1 1 1 1 EGF-like domain TMEM210 PF15195.6 GAM24415.1 - 0.0089 16.4 1.1 0.018 15.4 1.1 1.6 1 0 0 1 1 1 1 TMEM210 family EGF PF00008.27 GAM24415.1 - 0.17 12.2 8.1 0.35 11.2 8.1 1.5 1 0 0 1 1 1 0 EGF-like domain BING4CT PF08149.11 GAM24416.1 - 3.3e-31 106.9 0.8 4.2e-30 103.4 0.0 3.2 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 GAM24416.1 - 2.8e-08 34.3 0.1 0.0054 17.6 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM24416.1 - 6.3e-05 23.2 0.0 0.13 12.6 0.0 3.8 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM24416.1 - 0.00072 19.0 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain PQQ_2 PF13360.6 GAM24416.1 - 0.003 17.2 0.0 0.0084 15.7 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain FixO PF02433.15 GAM24416.1 - 0.075 12.5 1.7 0.17 11.3 1.7 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO SDA1 PF05285.12 GAM24416.1 - 0.24 10.8 30.2 0.014 14.8 14.0 2.1 2 0 0 2 2 2 0 SDA1 DNA_pol_phi PF04931.13 GAM24416.1 - 1.6 6.7 20.2 3 5.9 20.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi CPSF100_C PF13299.6 GAM24416.1 - 4.3 7.5 14.0 0.32 11.2 2.4 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Nop25 PF09805.9 GAM24417.1 - 8.5e-10 39.2 59.6 4.3e-09 37.0 47.9 4.1 2 1 0 3 3 3 1 Nucleolar protein 12 (25kDa) Nop14 PF04147.12 GAM24417.1 - 0.061 11.5 34.4 0.084 11.1 34.4 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GAM24417.1 - 9.2 5.5 44.5 0.062 12.6 31.9 2.1 2 0 0 2 2 2 0 BUD22 Cupin_8 PF13621.6 GAM24418.1 - 9.8e-22 77.9 2.8 1.9e-21 76.9 0.1 2.4 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 GAM24418.1 - 7.6e-12 45.7 3.1 1.1e-07 32.2 0.0 2.9 3 0 0 3 3 3 2 JmjC domain, hydroxylase Cupin_4 PF08007.12 GAM24418.1 - 4.2e-06 26.5 0.1 1.2e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 Cupin superfamily protein MPM1 PF17234.2 GAM24418.1 - 0.0092 16.3 1.7 0.0092 16.3 1.7 2.3 1 1 1 2 2 2 1 Mitochondrial peculiar membrane protein 1 Cupin_2 PF07883.11 GAM24418.1 - 0.019 14.6 0.0 0.07 12.9 0.0 1.9 2 0 0 2 2 2 0 Cupin domain DUF4407 PF14362.6 GAM24418.1 - 0.042 13.2 2.2 0.079 12.3 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1168 PF06658.12 GAM24418.1 - 0.053 13.3 9.9 0.35 10.7 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) PcfK PF14058.6 GAM24418.1 - 0.14 12.4 5.7 0.37 11.1 0.2 2.4 2 0 0 2 2 2 0 PcfK-like protein SPA PF08616.10 GAM24419.1 - 2.2e-12 46.9 0.1 4.5e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 GAM24419.1 - 4.1e-09 35.6 2.1 4.6e-09 35.5 0.1 2.2 2 1 0 2 2 2 1 Transport protein Avl9 DENN PF02141.21 GAM24419.1 - 0.00019 21.5 2.5 0.00061 19.8 0.4 2.8 2 1 0 2 2 2 1 DENN (AEX-3) domain Afi1 PF07792.12 GAM24419.1 - 0.0081 16.6 0.2 0.0081 16.6 0.2 2.6 3 0 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking F-box-like PF12937.7 GAM24420.1 - 4.2e-09 36.2 0.1 9.7e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM24420.1 - 3.6e-08 33.1 0.2 8.4e-08 31.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAM24420.1 - 0.00057 19.7 0.1 0.0013 18.6 0.1 1.6 1 0 0 1 1 1 1 F-box Secretin_N_2 PF07655.13 GAM24420.1 - 0.87 10.2 19.9 1.4 9.5 1.7 3.6 4 0 0 4 4 4 0 Secretin N-terminal domain R3H-assoc PF13902.6 GAM24421.1 - 3.5e-16 59.8 0.7 3.5e-16 59.8 0.7 1.7 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 GAM24421.1 - 0.069 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 R3H domain Glyco_hydro_9 PF00759.19 GAM24422.1 - 1.7e-128 429.6 5.4 2.1e-128 429.3 5.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 ATG16 PF08614.11 GAM24423.1 - 1.2e-41 143.2 20.5 1.5e-41 142.8 20.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 GAM24423.1 - 1.2e-33 114.5 31.6 2e-07 31.6 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM24423.1 - 5.9e-14 52.1 1.0 0.011 16.0 0.1 6.3 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM24423.1 - 7.4e-05 22.2 0.1 0.00096 18.6 0.0 2.6 2 0 0 2 2 2 1 WD40-like domain PALB2_WD40 PF16756.5 GAM24423.1 - 0.00031 19.8 1.8 0.71 8.7 0.2 3.3 2 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 GAM24423.1 - 0.019 13.9 4.5 2.8 6.8 0.0 3.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAM24423.1 - 0.037 14.0 1.4 0.31 11.0 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SNARE_assoc PF09335.11 GAM24424.1 - 6.8e-28 97.6 4.0 6.8e-28 97.6 4.0 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF1772 PF08592.11 GAM24424.1 - 0.089 13.1 2.1 0.94 9.8 0.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) Opy2 PF09463.10 GAM24425.1 - 0.036 14.4 42.3 0.95 9.8 11.0 5.0 1 1 3 4 4 4 0 Opy2 protein DUF1459 PF07312.11 GAM24425.1 - 0.061 13.5 7.7 1 9.6 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) TILa PF12714.7 GAM24425.1 - 4 7.5 28.8 0.36 10.8 2.1 3.9 2 2 2 4 4 4 0 TILa domain FNIP PF05725.12 GAM24426.1 - 3.5e-47 158.3 9.8 6.6e-11 42.2 1.1 5.8 3 1 2 6 6 6 5 FNIP Repeat LRR_8 PF13855.6 GAM24426.1 - 0.17 11.7 5.8 1.1 9.1 0.1 3.7 3 1 0 3 3 3 0 Leucine rich repeat ATP-grasp_2 PF08442.10 GAM24427.1 - 2.5e-74 249.2 0.5 3.6e-74 248.7 0.5 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 GAM24427.1 - 2.5e-27 95.6 2.6 5.5e-27 94.5 2.6 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 GAM24427.1 - 4.4e-12 45.9 0.2 6.6e-12 45.4 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAM24427.1 - 0.0004 20.2 0.5 0.00089 19.1 0.5 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 GAM24427.1 - 0.075 12.6 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain RA PF00788.23 GAM24427.1 - 0.14 12.8 0.0 0.53 11.0 0.0 1.9 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Peripla_BP_3 PF13377.6 GAM24427.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Kelch_1 PF01344.25 GAM24428.1 - 3.7e-21 74.4 8.2 4.9e-05 22.8 0.2 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 GAM24428.1 - 2.6e-15 56.1 11.5 0.0027 18.0 0.1 6.4 3 1 3 6 6 6 4 Kelch motif Kelch_4 PF13418.6 GAM24428.1 - 5.1e-14 52.0 7.7 0.085 12.9 0.1 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain zf-B_box PF00643.24 GAM24428.1 - 1.9e-07 31.1 10.8 3.9e-07 30.1 10.8 1.4 1 0 0 1 1 1 1 B-box zinc finger Kelch_2 PF07646.15 GAM24428.1 - 1.8e-06 27.7 9.2 0.12 12.4 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 GAM24428.1 - 0.006 16.9 0.0 0.006 16.9 0.0 5.5 6 1 0 6 6 6 1 Galactose oxidase, central domain GPS2_interact PF15784.5 GAM24428.1 - 0.0062 17.0 0.4 0.0062 17.0 0.4 3.4 3 1 0 3 3 3 1 G-protein pathway suppressor 2-interacting domain Kelch_5 PF13854.6 GAM24428.1 - 0.043 13.8 17.4 0.31 11.1 0.3 4.2 5 0 0 5 5 5 0 Kelch motif Auxin_repressed PF05564.12 GAM24428.1 - 0.59 10.8 11.6 2.5 8.8 4.0 2.6 2 0 0 2 2 2 0 Dormancy/auxin associated protein FNIP PF05725.12 GAM24429.1 - 7.6e-56 186.0 26.2 7.9e-13 48.4 0.7 6.5 3 1 5 8 8 8 7 FNIP Repeat GDP_Man_Dehyd PF16363.5 GAM24430.1 - 4.4e-29 101.9 0.0 5.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAM24430.1 - 7.2e-28 97.7 0.0 9.9e-28 97.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM24430.1 - 1.3e-18 67.0 0.0 2.3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAM24430.1 - 1.6e-11 43.9 0.1 2.4e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAM24430.1 - 3.2e-08 33.0 0.0 4.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAM24430.1 - 6.8e-06 25.4 0.0 0.00025 20.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 GAM24430.1 - 8.6e-06 25.8 0.1 5.7e-05 23.1 0.0 2.2 2 1 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 GAM24430.1 - 0.00012 22.4 0.1 0.00032 20.9 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAM24430.1 - 0.00037 20.0 0.4 0.0011 18.5 0.2 1.9 2 1 0 2 2 2 1 short chain dehydrogenase CBP_BcsR PF10945.8 GAM24430.1 - 0.044 13.3 0.1 0.092 12.2 0.1 1.6 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR zf-Di19 PF05605.12 GAM24431.1 - 1.3e-18 67.0 1.6 2.3e-18 66.2 1.6 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding SUIM_assoc PF16619.5 GAM24431.1 - 0.08 13.0 5.3 0.19 11.8 4.2 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PyrI_C PF02748.15 GAM24431.1 - 0.098 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Di19_C PF14571.6 GAM24431.1 - 0.12 12.9 14.7 0.061 13.9 9.1 2.9 2 1 1 3 3 3 0 Stress-induced protein Di19, C-terminal Spt20 PF12090.8 GAM24431.1 - 0.15 11.6 10.6 0.36 10.4 10.6 1.6 1 0 0 1 1 1 0 Spt20 family zf-UBR PF02207.20 GAM24431.1 - 0.34 11.1 3.0 0.64 10.2 3.0 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zinc_ribbon_10 PF10058.9 GAM24431.1 - 0.36 10.6 3.1 5.7 6.7 0.3 2.7 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein CDC45 PF02724.14 GAM24431.1 - 1.5 7.1 15.1 0.039 12.2 6.9 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF3947 PF13135.6 GAM24431.1 - 2.8 8.2 9.8 2.6 8.3 6.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) TCP PF03634.13 GAM24431.1 - 6.7 7.2 8.9 7.3 7.1 7.4 1.8 2 0 0 2 2 2 0 TCP family transcription factor Bap31 PF05529.12 GAM24432.1 - 5.3e-24 84.6 7.5 9.3e-24 83.8 7.5 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 GAM24432.1 - 3e-10 39.9 8.7 3e-10 39.9 8.7 2.3 1 1 1 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF3450 PF11932.8 GAM24432.1 - 0.00019 20.8 5.1 0.00035 20.0 5.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HALZ PF02183.18 GAM24432.1 - 0.00022 21.4 9.9 0.067 13.4 1.3 2.7 1 1 0 2 2 2 2 Homeobox associated leucine zipper YabA PF06156.13 GAM24432.1 - 0.00039 21.0 7.6 0.0011 19.6 7.3 1.8 1 1 0 1 1 1 1 Initiation control protein YabA Scaffolding_pro PF11418.8 GAM24432.1 - 0.00059 20.3 1.3 0.0012 19.4 1.1 1.6 1 1 0 1 1 1 1 Phi29 scaffolding protein CENP-F_leu_zip PF10473.9 GAM24432.1 - 0.0018 18.3 8.3 0.0025 17.9 8.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 GAM24432.1 - 0.0023 18.1 2.8 0.0028 17.8 2.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Sec34 PF04136.15 GAM24432.1 - 0.0059 16.5 6.9 0.48 10.3 0.2 2.2 1 1 1 2 2 2 2 Sec34-like family FapA PF03961.13 GAM24432.1 - 0.01 14.5 2.9 0.01 14.4 2.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 GAM24432.1 - 0.013 15.3 12.2 0.11 12.3 0.3 3.0 2 1 1 3 3 3 0 Septum formation initiator DUF948 PF06103.11 GAM24432.1 - 0.035 14.4 1.9 0.035 14.4 1.9 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 GAM24432.1 - 0.052 12.9 11.1 0.1 12.0 11.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fzo_mitofusin PF04799.13 GAM24432.1 - 0.082 12.5 4.1 0.15 11.6 4.1 1.5 1 0 0 1 1 1 0 fzo-like conserved region V-ATPase_G PF03179.15 GAM24432.1 - 0.094 13.3 8.6 0.15 12.6 8.6 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit KELK PF15796.5 GAM24432.1 - 0.16 12.5 11.1 0.47 10.9 11.0 1.9 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Seryl_tRNA_N PF02403.22 GAM24432.1 - 0.33 11.2 11.7 1.2 9.4 9.3 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 GAM24432.1 - 0.63 10.5 10.5 0.54 10.7 0.3 2.3 1 1 1 2 2 2 0 Cell division protein ZapB DUF4337 PF14235.6 GAM24432.1 - 0.77 9.9 5.9 1.3 9.1 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) APG6_N PF17675.1 GAM24432.1 - 1.9 9.0 14.7 0.84 10.2 10.7 2.1 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 GAM24432.1 - 3.5 6.9 8.2 6.4 6.0 8.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.32 GAM24433.1 - 4.5e-09 36.8 9.8 0.35 11.8 0.1 8.7 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM24433.1 - 1.1e-06 28.8 0.0 0.24 11.7 0.0 5.7 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAM24433.1 - 0.012 15.6 0.3 2.6 8.1 0.1 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat EMC3_TMCO1 PF01956.16 GAM24433.1 - 6.7 6.4 6.9 59 3.3 0.0 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like LRR_6 PF13516.6 GAM24434.1 - 7.7e-14 50.5 27.8 0.0033 17.3 0.0 9.2 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 GAM24434.1 - 3.6e-07 29.8 1.5 5.5 7.9 0.0 7.0 7 1 0 7 7 7 2 Leucine Rich Repeat Carm_PH PF17888.1 GAM24434.1 - 1.7e-05 25.1 0.3 6.3e-05 23.3 0.3 1.9 1 0 0 1 1 1 1 Carmil pleckstrin homology domain CARMIL_C PF16000.5 GAM24434.1 - 0.00067 19.4 23.3 0.11 12.0 16.4 2.3 2 0 0 2 2 2 2 CARMIL C-terminus Myosin_TH1 PF06017.13 GAM24434.1 - 0.0022 17.7 0.5 0.0022 17.7 0.5 2.6 3 0 0 3 3 3 1 Unconventional myosin tail, actin- and lipid-binding LRR_4 PF12799.7 GAM24434.1 - 0.0053 17.1 31.0 0.02 15.3 1.0 7.0 6 2 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM24434.1 - 0.14 11.9 12.9 0.33 10.7 2.4 5.1 4 2 0 4 4 4 0 Leucine rich repeat Lipase_GDSL_2 PF13472.6 GAM24435.1 - 3.1e-14 53.8 0.1 1e-13 52.0 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CE2_N PF17996.1 GAM24435.1 - 1.3e-13 50.8 0.0 3.4e-13 49.5 0.0 1.6 1 1 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL PF00657.22 GAM24435.1 - 1.5e-09 38.1 0.0 3.2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4183 PF13799.6 GAM24435.1 - 0.0027 17.5 0.5 0.017 15.0 0.6 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4183) CN_hydrolase PF00795.22 GAM24436.1 - 1.9e-51 174.9 0.0 2.4e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Y1_Tnp PF01797.16 GAM24436.1 - 0.1 12.7 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Transposase IS200 like ABC_tran PF00005.27 GAM24437.1 - 6.5e-25 88.2 0.0 1.4e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAM24437.1 - 5.1e-20 71.9 34.5 9.8e-20 70.9 34.5 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAM24437.1 - 1.4e-09 38.2 0.0 3.7e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAM24437.1 - 0.11 12.0 0.1 9.2 5.6 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM24437.1 - 0.16 12.5 0.4 0.41 11.1 0.4 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAM24437.1 - 1.2 9.0 4.4 0.37 10.6 0.2 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.7 GAM24437.1 - 2.5 7.3 15.1 1.8 7.8 12.9 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein DS PF01916.17 GAM24438.1 - 2.5e-132 440.5 0.0 2.9e-132 440.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Laterosporulin PF17861.1 GAM24439.1 - 0.026 14.9 0.2 0.1 13.1 0.2 2.0 1 0 0 1 1 1 0 Laterosporulin defensin-like peptide Na_Ca_ex PF01699.24 GAM24440.1 - 2.4e-12 47.1 11.1 3.1e-12 46.7 11.1 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Na_H_Exchanger PF00999.21 GAM24440.1 - 0.025 13.4 7.4 0.0069 15.2 4.3 1.5 1 1 0 1 1 1 0 Sodium/hydrogen exchanger family Wzy_C PF04932.15 GAM24440.1 - 0.32 10.6 4.5 0.12 12.0 1.7 1.8 1 1 0 1 1 1 0 O-Antigen ligase MARVEL PF01284.23 GAM24440.1 - 1.1 9.3 11.9 0.2 11.7 2.6 2.4 2 0 0 2 2 2 0 Membrane-associating domain Ribosomal_S9 PF00380.19 GAM24442.1 - 6.7e-33 113.8 0.1 1.2e-32 112.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF3482 PF11981.8 GAM24442.1 - 0.29 10.5 1.5 0.59 9.5 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Cytochrom_C PF00034.21 GAM24442.1 - 1.1 10.5 5.8 0.33 12.1 1.8 2.3 2 0 0 2 2 2 0 Cytochrome c GWT1 PF06423.12 GAM24443.1 - 0.1 12.7 4.4 0.59 10.3 3.6 2.2 2 1 0 2 2 2 0 GWT1 Claudin_3 PF06653.11 GAM24443.1 - 0.32 10.9 11.5 0.99 9.3 11.5 1.8 1 1 0 1 1 1 0 Tight junction protein, Claudin-like MARVEL PF01284.23 GAM24443.1 - 0.51 10.4 9.3 0.34 10.9 6.5 2.1 1 1 1 2 2 2 0 Membrane-associating domain Acyl-CoA_dh_M PF02770.19 GAM24444.1 - 3.7e-18 65.5 0.1 1.1e-17 64.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAM24444.1 - 4.5e-10 39.9 0.6 1.4e-09 38.4 0.1 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 GAM24444.1 - 4e-09 36.3 0.0 6.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase GSDH PF07995.11 GAM24445.1 - 1.3e-10 41.1 0.1 2.2e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase RIFIN PF02009.16 GAM24445.1 - 0.19 11.6 7.2 0.28 11.0 7.2 1.2 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 GAM24445.1 - 1.8 7.9 7.2 2.5 7.4 7.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CBM_10 PF02013.16 GAM24445.1 - 1.8 9.1 8.5 5.5 7.6 0.9 3.2 2 1 0 2 2 2 0 Cellulose or protein binding domain SOG2 PF10428.9 GAM24445.1 - 3.5 6.7 26.4 4.9 6.2 26.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GRAM PF02893.20 GAM24446.1 - 2.8e-13 49.8 0.2 5.5e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 GRAM domain V-SNARE_C PF12352.8 GAM24446.1 - 2.2e-07 31.1 7.4 9.7e-06 25.8 1.4 2.7 2 1 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 GAM24446.1 - 0.00015 21.7 2.6 0.011 15.7 0.1 2.5 2 0 0 2 2 2 2 SNARE domain DUF5089 PF17002.5 GAM24446.1 - 0.027 14.3 5.8 0.26 11.1 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) NPV_P10 PF05531.12 GAM24446.1 - 0.076 13.5 0.4 35 4.9 0.3 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FliJ PF02050.16 GAM24446.1 - 4.5 7.5 6.3 4.6 7.5 0.2 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein DUF1870 PF08965.10 GAM24447.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) ubiquitin PF00240.23 GAM24448.1 - 9.6e-133 432.1 19.9 1.3e-32 111.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 GAM24448.1 - 4.1e-61 202.7 20.9 1e-14 54.1 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAM24448.1 - 2.6e-21 75.8 9.8 0.0012 19.3 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 GAM24448.1 - 4.5e-15 55.4 3.1 0.058 13.3 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAM24448.1 - 1e-14 54.7 6.5 0.046 14.1 0.0 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM24448.1 - 1.3e-13 51.1 1.6 0.22 11.7 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAM24448.1 - 5e-12 46.3 0.8 0.61 10.7 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAM24448.1 - 4.5e-06 26.6 21.6 25 5.0 0.0 7.9 8 0 0 8 8 8 0 Ubiquitin-like domain DUF2870 PF11069.8 GAM24448.1 - 5.1e-06 26.8 0.0 30 5.1 0.0 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 GAM24448.1 - 5.2e-06 26.0 0.5 2.2 7.6 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase Big_3_3 PF13750.6 GAM24448.1 - 1.4e-05 24.8 0.0 19 4.9 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) DUF969 PF06149.12 GAM24448.1 - 6.5e-05 22.4 0.1 20 4.5 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF969) Big_7 PF17957.1 GAM24448.1 - 0.00013 22.7 0.1 69 4.3 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 GAM24448.1 - 0.00018 21.6 2.3 11 6.2 0.0 3.9 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_5 PF13710.6 GAM24448.1 - 0.00035 20.3 2.8 33 4.4 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.7 GAM24448.1 - 0.00038 20.6 1.5 49 4.2 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF3435 PF11917.8 GAM24448.1 - 0.0005 19.1 0.2 25 3.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3435) Corona_NS2A PF05213.12 GAM24448.1 - 0.0014 18.0 0.1 42 3.4 0.0 3.9 4 0 0 4 4 4 0 Coronavirus NS2A protein ORF11CD3 PF10549.9 GAM24448.1 - 0.0032 17.5 0.0 92 3.3 0.0 4.6 4 0 0 4 4 4 0 ORF11CD3 domain Raf1_HTH PF18579.1 GAM24448.1 - 0.004 16.8 0.2 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain NEAT PF05031.12 GAM24448.1 - 0.0045 17.6 2.6 3.8 8.1 0.4 3.0 1 1 2 3 3 3 3 Iron Transport-associated domain Imm12 PF15560.6 GAM24448.1 - 0.005 16.8 1.5 76 3.3 0.0 4.0 4 0 0 4 4 4 0 Immunity protein 12 YcgR_2 PF12945.7 GAM24448.1 - 0.014 15.5 6.3 56 4.0 0.1 4.2 4 0 0 4 4 4 0 Flagellar protein YcgR ACT_4 PF13291.6 GAM24448.1 - 0.022 15.3 0.3 2.3e+02 2.4 0.0 4.1 4 0 0 4 4 4 0 ACT domain Myosin_N PF02736.19 GAM24448.1 - 0.12 12.2 5.5 1.1e+02 2.8 0.0 5.3 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain Phage-tail_1 PF09097.10 GAM24448.1 - 0.28 10.9 0.6 2e+02 1.6 0.0 3.6 4 0 0 4 4 4 0 Baseplate structural protein, domain 1 ProRS-C_2 PF09181.10 GAM24448.1 - 1.1 9.5 4.6 2.3e+02 2.0 0.0 3.9 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 GAM24448.1 - 2.3 8.1 8.7 1.3e+02 2.5 0.1 4.2 4 0 0 4 4 4 0 FlgD Ig-like domain PH_15 PF17339.2 GAM24448.1 - 5.4 7.0 6.3 1.1e+02 2.8 0.1 3.5 4 0 0 4 4 4 0 PH domain ALAD PF00490.21 GAM24449.1 - 1.8e-122 408.5 0.0 2e-122 408.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Patatin PF01734.22 GAM24450.1 - 6.9e-13 49.2 0.1 1.6e-12 48.0 0.1 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase PH PF00169.29 GAM24450.1 - 1.1e-08 35.5 1.8 2.6e-08 34.3 1.8 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM24450.1 - 1.6 9.2 7.1 12 6.4 7.1 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Response_reg PF00072.24 GAM24451.1 - 3.7e-14 52.8 0.0 7.7e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain LRR_4 PF12799.7 GAM24451.1 - 2.8e-05 24.4 26.8 0.72 10.4 0.7 6.8 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM24451.1 - 0.0047 16.7 21.8 0.1 12.4 2.4 5.3 4 1 2 6 6 6 4 Leucine rich repeat LRR_6 PF13516.6 GAM24451.1 - 2.2 8.6 36.6 5.4 7.3 1.3 9.5 11 0 0 11 11 11 0 Leucine Rich repeat LRR_1 PF00560.33 GAM24451.1 - 2.6 8.9 29.8 6.5 7.7 0.3 8.6 8 1 0 8 8 8 0 Leucine Rich Repeat EMC3_TMCO1 PF01956.16 GAM24452.1 - 4.1e-38 130.8 13.3 5e-38 130.5 9.1 2.3 2 1 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like GST_N_3 PF13417.6 GAM24453.1 - 2.2e-12 47.2 0.0 3.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM24453.1 - 1.2e-11 44.7 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM24453.1 - 1.2e-10 41.6 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM24453.1 - 1.6e-08 34.6 0.0 2.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM24453.1 - 0.00019 21.6 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAM24453.1 - 0.0076 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 GAM24453.1 - 0.031 14.3 0.0 0.075 13.1 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain NUC153 PF08159.12 GAM24453.1 - 0.086 12.7 1.0 38 4.2 0.0 3.4 3 0 0 3 3 3 0 NUC153 domain Ank_5 PF13857.6 GAM24454.1 - 0.0021 18.3 1.3 0.78 10.1 0.0 3.7 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM24454.1 - 0.005 17.4 0.3 0.015 15.8 0.1 1.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Raco_middle PF17651.1 GAM24454.1 - 0.018 14.7 0.1 0.054 13.2 0.1 1.7 2 0 0 2 2 2 0 RACo middle region Ank_4 PF13637.6 GAM24454.1 - 0.031 14.9 0.2 1.6 9.4 0.1 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) LRR_8 PF13855.6 GAM24456.1 - 9.2e-14 51.0 17.0 4.4e-09 36.0 5.6 4.3 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 GAM24456.1 - 4.6e-10 39.6 23.9 1.9e-05 24.9 2.7 4.7 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM24456.1 - 0.00032 20.9 18.9 11 7.0 0.0 7.4 7 1 1 8 8 8 2 Leucine Rich Repeat RasGEF PF00617.19 GAM24457.1 - 3.3e-35 121.9 0.1 8.1e-35 120.6 0.1 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM24457.1 - 4.4e-05 23.7 5.0 4.4e-05 23.7 5.0 3.1 2 1 0 2 2 2 1 RasGEF N-terminal motif DUF2888 PF11135.8 GAM24458.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) RasGEF PF00617.19 GAM24461.1 - 1.6e-33 116.4 0.1 2.7e-33 115.6 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM24461.1 - 0.0017 18.6 0.3 0.0056 16.9 0.1 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Actin PF00022.19 GAM24462.1 - 2.4e-22 79.1 0.0 4.5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Actin AIG1 PF04548.16 GAM24462.1 - 6.7e-08 32.1 2.1 7.1e-08 32.0 0.1 2.0 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 GAM24462.1 - 3.2e-06 27.2 0.4 9e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAM24462.1 - 0.0041 17.7 2.8 0.0063 17.0 0.1 2.2 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 GAM24462.1 - 0.0077 16.2 1.2 0.012 15.5 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 GAM24462.1 - 0.013 14.7 3.2 0.015 14.6 0.3 2.2 2 0 0 2 2 2 0 Septin HSP70 PF00012.20 GAM24462.1 - 0.025 12.8 1.7 0.38 8.9 0.0 2.2 2 0 0 2 2 2 0 Hsp70 protein G-alpha PF00503.20 GAM24462.1 - 0.08 12.1 1.3 0.87 8.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit GTP_EFTU_D3 PF03143.17 GAM24462.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain AAA_18 PF13238.6 GAM24462.1 - 0.26 11.8 2.1 0.96 10.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain UPF0242 PF06785.11 GAM24462.1 - 0.53 10.4 9.8 0.94 9.5 9.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus p450 PF00067.22 GAM24463.1 - 6.6e-64 216.3 0.0 7.3e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_3 PF13606.6 GAM24464.1 - 0.0018 18.6 0.9 3.3 8.6 0.4 4.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 GAM24464.1 - 0.2 12.3 2.7 4 8.1 0.2 3.3 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 GAM24465.1 - 5.4e-07 30.1 13.4 0.19 12.4 0.0 8.5 9 2 1 10 10 10 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM24465.1 - 0.27 11.9 10.5 3.8e+02 2.2 0.0 9.5 12 0 0 12 12 12 0 Ankyrin repeat MBA1 PF07961.11 GAM24468.1 - 0.019 14.0 0.7 0.022 13.8 0.7 1.1 1 0 0 1 1 1 0 MBA1-like protein Tim44 PF04280.15 GAM24468.1 - 0.037 14.1 0.1 6.1 6.9 0.1 2.2 1 1 1 2 2 2 0 Tim44-like domain CBM49 PF09478.10 GAM24469.1 - 2.1e-27 95.3 0.1 4.4e-15 55.7 0.1 2.2 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 GhoS PF11080.8 GAM24470.1 - 0.026 14.5 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 Endoribonuclease GhoS DNA_ligase_A_M PF01068.21 GAM24471.1 - 2.5e-47 161.2 0.0 7.3e-47 159.6 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAM24471.1 - 2.8e-36 125.4 0.4 2.8e-36 125.4 0.4 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 GAM24471.1 - 1.6e-20 73.5 0.0 3.8e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 GAM24471.1 - 4.6e-14 52.6 0.7 5.6e-10 39.5 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAM24471.1 - 1.4e-12 47.8 1.4 2.5e-09 37.4 0.2 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 GAM24471.1 - 1.2e-10 41.4 0.3 2.4e-10 40.3 0.3 1.6 1 0 0 1 1 1 1 DNA ligase IV RNA_ligase PF09414.10 GAM24471.1 - 4e-09 37.0 0.2 1.5e-08 35.2 0.0 2.1 3 0 0 3 3 3 1 RNA ligase mRNA_cap_enzyme PF01331.19 GAM24471.1 - 1.9e-05 24.6 5.2 0.003 17.4 0.0 3.5 4 0 0 4 4 4 2 mRNA capping enzyme, catalytic domain LIG3_BRCT PF16759.5 GAM24471.1 - 0.013 15.7 0.4 0.047 14.0 0.1 2.1 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain EF-hand_1 PF00036.32 GAM24472.1 - 2.5e-12 45.4 0.7 1.9e-06 27.0 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAM24472.1 - 7.3e-11 42.4 0.2 1.8e-10 41.1 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM24472.1 - 3.3e-09 36.0 0.1 4.1e-05 23.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAM24472.1 - 2.3e-08 33.8 0.3 7.1e-06 25.8 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair VWA PF00092.28 GAM24472.1 - 2.4e-07 31.2 0.0 6.1e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM24472.1 - 4.5e-07 30.5 0.0 4.2e-06 27.3 0.0 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain WWE PF02825.20 GAM24472.1 - 2.3e-06 28.1 0.0 5.2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 WWE domain EF-hand_9 PF14658.6 GAM24472.1 - 1.8e-05 25.0 0.0 4.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 GAM24472.1 - 0.00029 20.2 0.0 0.00075 18.9 0.0 1.7 1 0 0 1 1 1 1 EF hand Sigma70_ner PF04546.13 GAM24472.1 - 0.016 15.1 0.5 0.029 14.3 0.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.13 GAM24472.1 - 0.023 14.8 0.8 0.023 14.8 0.8 1.8 2 0 0 2 2 2 0 YL1 nuclear protein ABC2_membrane_3 PF12698.7 GAM24472.1 - 0.055 12.6 0.0 0.055 12.6 0.0 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein PBP1_TM PF14812.6 GAM24472.1 - 0.23 11.8 2.4 0.52 10.7 2.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribonuc_red_sm PF00268.21 GAM24473.1 - 1.1e-117 392.5 2.2 1.2e-117 392.3 2.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain KTSC PF13619.6 GAM24473.1 - 0.043 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 KTSC domain Phage_SSB PF16773.5 GAM24474.1 - 0.015 15.4 0.8 0.055 13.5 0.8 2.0 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein F-box-like PF12937.7 GAM24474.1 - 0.023 14.6 0.1 0.08 12.9 0.1 1.9 1 0 0 1 1 1 0 F-box-like His_biosynth PF00977.21 GAM24474.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF4637 PF15470.6 GAM24474.1 - 5.7 6.6 10.9 18 5.0 10.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PhoLip_ATPase_C PF16212.5 GAM24475.1 - 2e-76 257.0 26.7 2e-76 257.0 26.7 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM24475.1 - 1.9e-23 81.9 0.4 6.7e-23 80.2 0.4 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 GAM24475.1 - 2.1e-14 53.4 1.5 6.3e-14 51.9 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAM24475.1 - 2.1e-12 47.0 0.0 4.6e-11 42.7 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM24475.1 - 2.1e-07 31.4 0.0 0.019 15.3 0.0 3.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAM24475.1 - 0.00072 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 GAM24476.1 - 0.0001 22.8 0.9 2.2 8.9 0.0 3.8 2 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM24476.1 - 0.00014 22.1 2.8 30 5.6 0.0 6.3 7 0 0 7 7 7 0 Ankyrin repeat Glutaminase PF04960.15 GAM24476.1 - 0.00072 18.8 0.2 0.0014 17.9 0.2 1.3 1 0 0 1 1 1 1 Glutaminase Ank_4 PF13637.6 GAM24476.1 - 0.0051 17.4 0.6 61 4.4 0.0 4.7 4 2 0 4 4 4 0 Ankyrin repeats (many copies) LINES_C PF14695.6 GAM24476.1 - 0.046 13.2 0.1 0.14 11.7 0.1 1.9 1 1 0 1 1 1 0 Lines C-terminus PTE PF02126.18 GAM24476.1 - 0.05 13.0 0.3 0.11 11.9 0.3 1.6 1 1 0 1 1 1 0 Phosphotriesterase family Ank_2 PF12796.7 GAM24477.1 - 3.6e-09 37.1 1.1 0.071 13.7 0.0 4.7 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM24477.1 - 5.4e-05 23.7 6.8 12 6.6 0.0 6.6 4 2 4 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM24477.1 - 0.0047 17.2 0.3 11 6.5 0.0 4.6 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM24477.1 - 0.015 15.8 2.9 84 4.3 0.0 6.7 7 0 0 7 7 7 0 Ankyrin repeat BCS1_N PF08740.11 GAM24478.1 - 5.8e-14 52.5 0.8 8e-14 52.0 0.8 1.2 1 0 0 1 1 1 1 BCS1 N terminal FAD_binding_1 PF00667.20 GAM24479.1 - 2e-33 115.8 1.3 2.6e-33 115.5 0.0 1.8 3 0 0 3 3 3 1 FAD binding domain Oxidored-like PF09791.9 GAM24479.1 - 1.2e-14 53.7 3.3 1.2e-14 53.7 3.3 2.0 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal NAD_binding_1 PF00175.21 GAM24479.1 - 2.8e-14 53.7 3.7 2.6e-13 50.6 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAM24479.1 - 0.0084 16.2 1.2 0.043 13.9 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SNF5 PF04855.12 GAM24479.1 - 0.015 15.1 3.6 0.81 9.4 0.0 2.3 2 0 0 2 2 2 0 SNF5 / SMARCB1 / INI1 MPM1 PF17234.2 GAM24479.1 - 0.14 12.5 5.5 0.71 10.1 4.8 2.1 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF2722 PF10846.8 GAM24479.1 - 1.4 7.8 12.2 0.12 11.2 5.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) SIR2_2 PF13289.6 GAM24479.1 - 1.5 8.9 4.1 0.33 11.1 0.2 1.8 2 0 0 2 2 2 0 SIR2-like domain CTU2 PF10288.9 GAM24479.1 - 3.1 8.1 7.5 0.26 11.5 0.8 2.4 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 CAP PF00188.26 GAM24480.1 - 2.7e-10 41.1 1.2 2.7e-10 41.1 1.2 2.8 3 1 0 3 3 3 1 Cysteine-rich secretory protein family CAP PF00188.26 GAM24481.1 - 0.00048 21.0 0.0 0.003 18.4 0.0 2.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family RIFIN PF02009.16 GAM24481.1 - 0.007 16.3 4.4 0.0091 15.9 4.4 1.1 1 0 0 1 1 1 1 Rifin SOG2 PF10428.9 GAM24481.1 - 0.13 11.4 32.6 0.18 10.9 32.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Suf PF05843.14 GAM24481.1 - 0.73 9.8 3.9 0.98 9.3 3.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Allantoicase PF03561.15 GAM24482.1 - 2.4e-99 329.2 0.0 1.3e-49 167.9 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Rhomboid PF01694.22 GAM24483.1 - 2.5e-37 128.2 14.1 2.5e-37 128.2 14.1 1.5 2 0 0 2 2 2 1 Rhomboid family Ribosomal_L6 PF00347.23 GAM24484.1 - 3.2e-22 79.0 7.4 2.6e-13 50.4 2.2 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 DUF1738 PF08401.11 GAM24484.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) DUF1108 PF06531.11 GAM24484.1 - 0.1 12.9 1.4 1.2 9.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1108) ADK PF00406.22 GAM24485.1 - 5.1e-46 156.5 0.0 7.3e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAM24485.1 - 4.5e-23 82.2 0.0 9.8e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 GAM24485.1 - 4.6e-14 52.1 0.2 1.2e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 GAM24485.1 - 1.3e-06 28.6 0.1 7.4e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM24485.1 - 2.3e-06 28.2 0.1 1.9e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 GAM24485.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase Thymidylate_kin PF02223.17 GAM24485.1 - 0.19 11.4 4.6 2.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase AAA_28 PF13521.6 GAM24485.1 - 0.3 11.3 2.4 0.18 12.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 GAM24485.1 - 0.43 10.8 8.1 8.7 6.6 0.0 2.7 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain TraB PF01963.17 GAM24486.1 - 9.8e-08 32.2 0.0 7.5e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 TraB family DUF2642 PF10842.8 GAM24486.1 - 0.14 12.1 0.3 0.56 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) TraB PF01963.17 GAM24487.1 - 1.9e-06 28.0 0.0 2.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 TraB family Cofac_haem_bdg PF04187.13 GAM24487.1 - 0.19 11.7 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN RRM_1 PF00076.22 GAM24488.1 - 2.2e-14 53.0 0.0 6.1e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CPBP PF02517.16 GAM24489.1 - 1.4e-17 63.8 5.5 1.4e-17 63.8 5.5 2.0 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Velvet PF11754.8 GAM24489.1 - 0.00092 19.2 3.1 0.00097 19.2 3.1 1.2 1 0 0 1 1 1 1 Velvet factor DDHD PF02862.17 GAM24489.1 - 0.0031 17.7 3.2 0.0039 17.4 3.2 1.2 1 0 0 1 1 1 1 DDHD domain Pex14_N PF04695.13 GAM24489.1 - 0.012 16.2 12.7 0.03 15.0 12.7 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4407 PF14362.6 GAM24489.1 - 0.017 14.5 9.7 0.027 13.8 8.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4760 PF15956.5 GAM24489.1 - 0.071 13.2 3.8 0.48 10.5 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4760) Macoilin PF09726.9 GAM24489.1 - 0.099 11.2 8.4 0.12 10.9 8.4 1.2 1 0 0 1 1 1 0 Macoilin family Pox_Ag35 PF03286.14 GAM24489.1 - 0.15 11.9 10.9 0.22 11.3 10.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Vma12 PF11712.8 GAM24489.1 - 0.21 11.7 1.4 0.46 10.6 1.4 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Tim54 PF11711.8 GAM24489.1 - 0.34 9.6 10.3 0.46 9.2 10.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 GAM24489.1 - 0.37 10.5 6.6 0.73 9.5 6.6 1.6 1 0 0 1 1 1 0 Connexin PTPRCAP PF15713.5 GAM24489.1 - 0.52 10.6 15.1 0.72 10.1 15.1 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RPN2_C PF18004.1 GAM24489.1 - 0.57 10.1 17.3 0.8 9.6 17.3 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Dicty_REP PF05086.12 GAM24489.1 - 0.61 8.0 13.8 0.78 7.6 13.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EMC3_TMCO1 PF01956.16 GAM24489.1 - 0.66 9.7 7.0 0.13 12.0 2.2 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Spt20 PF12090.8 GAM24489.1 - 0.76 9.3 38.7 1.3 8.6 38.7 1.3 1 0 0 1 1 1 0 Spt20 family SAPS PF04499.15 GAM24489.1 - 0.81 8.4 11.0 1.1 7.9 11.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Afi1 PF07792.12 GAM24489.1 - 0.94 10.0 13.2 1.6 9.2 13.2 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking VIT1 PF01988.19 GAM24489.1 - 1.1 9.1 4.1 2.7 7.8 1.7 2.2 2 0 0 2 2 2 0 VIT family eIF-3_zeta PF05091.12 GAM24489.1 - 1.3 7.9 17.1 1.8 7.5 17.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TraS PF10624.9 GAM24489.1 - 1.8 8.5 6.0 0.3 11.0 1.6 1.9 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS Suf PF05843.14 GAM24489.1 - 1.8 8.5 12.8 2.9 7.8 12.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ALMT PF11744.8 GAM24489.1 - 1.9 7.2 11.9 3.3 6.4 11.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Pannexin_like PF12534.8 GAM24489.1 - 2.3 7.2 8.5 4.1 6.4 8.5 1.4 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 SPATA3 PF15662.5 GAM24489.1 - 3.4 8.3 13.2 4.9 7.7 13.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family TFIIA PF03153.13 GAM24489.1 - 3.5 7.5 33.6 4.8 7.1 33.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 GAM24489.1 - 4.2 7.3 12.0 6.9 6.6 12.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PPL5 PF18168.1 GAM24489.1 - 4.3 6.5 13.2 6.6 5.9 13.2 1.3 1 0 0 1 1 1 0 Prim-pol family 5 SpoIIP PF07454.11 GAM24489.1 - 4.4 6.7 15.9 6.2 6.2 15.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2157 PF09925.9 GAM24489.1 - 4.9 6.9 9.0 40 4.0 9.0 2.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) FAM60A PF15396.6 GAM24489.1 - 7.7 6.5 12.3 12 5.9 12.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Plasmodium_Vir PF05795.11 GAM24489.1 - 7.7 5.8 9.8 11 5.3 9.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PAT1 PF09770.9 GAM24489.1 - 7.8 4.6 23.5 9.6 4.3 23.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CCSAP PF15748.5 GAM24489.1 - 8.1 6.5 21.4 11 6.0 21.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Band_3_cyto PF07565.13 GAM24489.1 - 8.3 6.1 15.4 13 5.5 15.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4746 PF15928.5 GAM24489.1 - 9.4 5.6 16.0 14 5.0 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Piwi PF02171.17 GAM24490.1 - 3.6e-77 259.6 0.1 5.9e-77 258.9 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 GAM24490.1 - 8.4e-23 80.7 0.9 1.8e-22 79.6 0.9 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 GAM24490.1 - 1.4e-05 24.6 0.0 3.8e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain Aldo_ket_red PF00248.21 GAM24491.1 - 1.2e-56 192.1 0.1 1.5e-54 185.2 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family YqhG PF11079.8 GAM24491.1 - 0.0017 17.4 0.1 0.0024 16.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein YqhG of unknown function Pkinase PF00069.25 GAM24492.1 - 3.4e-42 144.7 0.1 4.6e-15 55.7 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24492.1 - 2.2e-22 79.6 0.0 1.2e-07 31.3 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 GAM24492.1 - 0.00043 19.7 0.0 0.00095 18.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIC3 PF15361.6 GAM24492.1 - 0.01 16.3 1.7 0.019 15.4 0.1 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 SDA1 PF05285.12 GAM24492.1 - 0.042 13.3 12.4 0.075 12.4 12.4 1.3 1 0 0 1 1 1 0 SDA1 FTA2 PF13095.6 GAM24492.1 - 0.071 12.7 0.2 2.9 7.5 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DNA_pol_phi PF04931.13 GAM24492.1 - 3.9 5.4 23.7 6.1 4.8 23.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GAM24492.1 - 6.8 5.1 15.1 1 7.8 1.1 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 GAM24492.1 - 9.8 4.3 17.7 2.6 6.2 3.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Metallophos PF00149.28 GAM24494.1 - 1.7e-12 48.3 0.2 2.8e-12 47.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1496 PF07383.12 GAM24494.1 - 0.067 12.8 0.4 1.2 8.8 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1496) HD_5 PF13487.6 GAM24495.1 - 0.12 12.6 0.9 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 HD domain His_Phos_1 PF00300.22 GAM24496.1 - 3.4e-17 62.8 0.1 3.7e-15 56.1 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_C80 PF11713.8 GAM24496.1 - 0.014 15.6 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase C80 family Coiled PF05710.12 GAM24497.1 - 0.15 12.9 15.8 0.2 12.5 15.8 1.3 1 1 0 1 1 1 0 Coiled coil Cyclin_N PF00134.23 GAM24499.1 - 2.9e-41 140.2 1.4 2.9e-41 140.2 1.4 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAM24499.1 - 3.7e-35 120.6 0.9 7.8e-35 119.5 0.9 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ank_2 PF12796.7 GAM24500.1 - 3.9e-48 162.0 18.0 7.9e-13 48.8 0.5 5.5 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) SIR2 PF02146.17 GAM24500.1 - 4e-43 147.4 0.0 1.3e-42 145.7 0.0 1.8 2 0 0 2 2 2 1 Sir2 family Ank_5 PF13857.6 GAM24500.1 - 1e-41 140.4 11.5 1.9e-08 34.4 0.0 6.6 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM24500.1 - 1.3e-39 132.9 20.5 2.4e-05 24.6 0.4 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 GAM24500.1 - 3.8e-36 123.0 17.0 6e-08 33.1 0.2 7.5 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM24500.1 - 2.1e-35 116.7 14.2 0.00051 20.3 0.0 9.8 9 1 0 9 9 9 7 Ankyrin repeat Glyco_hydro_16 PF00722.21 GAM24501.1 - 1e-41 142.3 0.3 7.5e-26 90.7 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 SKN1 PF03935.15 GAM24501.1 - 1e-18 67.1 8.1 3.3e-06 25.8 0.3 4.1 3 1 1 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) Ank_2 PF12796.7 GAM24502.1 - 2.9e-27 95.1 33.9 2.1e-07 31.4 0.5 7.1 3 3 8 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM24502.1 - 3.9e-23 81.5 17.1 1.2e-06 28.9 0.1 9.8 10 0 0 10 10 10 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM24502.1 - 1.4e-22 79.4 20.3 7.7e-05 22.9 0.1 11.8 7 2 6 13 13 13 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM24502.1 - 2.3e-09 36.7 15.3 11 6.9 0.0 12.1 13 1 1 14 14 14 2 Ankyrin repeat Ank PF00023.30 GAM24502.1 - 0.0052 17.2 6.7 72 4.1 0.1 7.9 8 1 0 8 8 8 0 Ankyrin repeat FNIP PF05725.12 GAM24503.1 - 1.7e-56 188.2 0.9 2.7e-12 46.7 0.0 10.3 6 2 7 13 13 13 11 FNIP Repeat LRR_5 PF13306.6 GAM24503.1 - 0.032 14.2 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 GAM24503.1 - 0.04 14.3 5.8 0.11 13.0 0.5 4.2 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) MFS_2 PF13347.6 GAM24504.1 - 1.7e-98 330.0 34.3 2e-98 329.8 34.3 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 GAM24504.1 - 3.9e-20 72.1 44.6 3.4e-15 55.8 27.5 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF4519 PF15012.6 GAM24504.1 - 0.11 12.7 1.8 0.37 11.0 1.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Bact_lectin PF18483.1 GAM24505.1 - 1.7e-21 77.1 0.2 2.7e-21 76.5 0.2 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 GAM24505.1 - 1.7e-17 63.8 0.1 2.6e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 Legume lectin domain Gin PF10764.9 GAM24505.1 - 0.08 12.9 0.2 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin zf-CCCH PF00642.24 GAM24506.1 - 9.7e-12 44.5 13.0 6.3e-07 29.2 1.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAM24506.1 - 3.3e-05 23.8 11.7 0.00036 20.5 1.0 2.5 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 GAM24506.1 - 0.00026 20.8 0.0 0.0018 18.1 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 GAM24506.1 - 0.00082 20.0 1.4 0.72 10.6 0.1 2.4 2 0 0 2 2 2 2 Torus domain RRM_3 PF08777.11 GAM24506.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif zf-CCCH_3 PF15663.5 GAM24506.1 - 0.2 11.9 1.1 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger containing family Mito_carr PF00153.27 GAM24507.1 - 8.6e-60 198.7 3.6 6.8e-19 67.6 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF4201 PF13870.6 GAM24508.1 - 0.00015 21.6 10.5 0.00019 21.2 10.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) ADIP PF11559.8 GAM24508.1 - 0.00032 20.8 15.9 0.00037 20.6 15.9 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 GAM24508.1 - 0.0018 18.6 16.2 0.43 10.9 3.9 3.2 2 1 1 3 3 3 2 Csm1 N-terminal domain DUF812 PF05667.11 GAM24508.1 - 0.0038 16.2 17.4 0.0064 15.4 17.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF812) TcpS PF17456.2 GAM24508.1 - 0.0056 16.7 6.0 0.0072 16.4 6.0 1.2 1 0 0 1 1 1 1 Toxin-coregulated pilus protein S ERM PF00769.19 GAM24508.1 - 0.0078 16.1 10.0 0.0099 15.7 10.0 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 GAM24508.1 - 0.013 15.5 10.6 0.016 15.3 10.6 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 GAM24508.1 - 0.015 15.6 9.0 0.44 10.9 0.4 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family APG6_N PF17675.1 GAM24508.1 - 0.021 15.4 14.7 0.05 14.1 14.7 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 GAM24508.1 - 0.033 14.3 6.8 0.033 14.3 6.8 2.1 1 1 1 2 2 2 0 TolA binding protein trimerisation DivIC PF04977.15 GAM24508.1 - 0.033 14.0 17.6 0.27 11.0 5.3 3.0 1 1 2 3 3 3 0 Septum formation initiator DUF641 PF04859.12 GAM24508.1 - 0.04 14.3 12.3 0.99 9.8 6.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Syntaxin-6_N PF09177.11 GAM24508.1 - 0.057 14.0 11.1 0.12 12.9 9.9 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.7 GAM24508.1 - 0.063 13.4 14.8 0.053 13.7 9.9 2.2 1 1 1 2 2 2 0 Tropomyosin like Golgin_A5 PF09787.9 GAM24508.1 - 0.08 12.4 12.6 0.1 12.1 12.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 SKA1 PF07160.12 GAM24508.1 - 0.086 12.7 10.0 0.12 12.2 10.0 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 bZIP_1 PF00170.21 GAM24508.1 - 0.09 12.9 13.2 0.15 12.2 1.8 3.0 2 1 1 3 3 3 0 bZIP transcription factor TMF_TATA_bd PF12325.8 GAM24508.1 - 0.092 13.0 11.6 0.46 10.7 11.6 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 GAM24508.1 - 0.094 13.4 11.5 1.4 9.6 5.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 GAM24508.1 - 0.1 11.9 14.0 0.12 11.6 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) End3 PF12761.7 GAM24508.1 - 0.1 12.8 11.9 0.14 12.3 11.9 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 ABC_tran_CTD PF16326.5 GAM24508.1 - 0.11 12.8 10.6 3.1 8.1 10.6 2.6 1 1 0 1 1 1 0 ABC transporter C-terminal domain Interferon PF00143.19 GAM24508.1 - 0.17 12.1 7.3 0.2 11.8 7.3 1.1 1 0 0 1 1 1 0 Interferon alpha/beta domain HemX PF04375.14 GAM24508.1 - 0.18 11.0 15.4 0.11 11.8 12.6 1.8 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Fez1 PF06818.15 GAM24508.1 - 0.21 12.0 13.5 0.13 12.7 5.4 2.0 1 1 1 2 2 2 0 Fez1 Atg14 PF10186.9 GAM24508.1 - 0.42 9.7 10.1 0.53 9.3 10.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 GAM24508.1 - 0.42 10.9 12.2 0.34 11.2 7.9 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Jnk-SapK_ap_N PF09744.9 GAM24508.1 - 0.59 10.3 13.0 0.62 10.3 11.2 1.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3573 PF12097.8 GAM24508.1 - 0.6 8.9 5.3 0.6 8.9 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TMF_DNA_bd PF12329.8 GAM24508.1 - 0.78 9.8 17.5 0.37 10.8 10.8 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.12 GAM24508.1 - 0.89 10.1 13.8 6.1 7.4 13.9 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 GAM24508.1 - 1 9.2 12.8 0.31 10.8 9.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMPIT PF07851.13 GAM24508.1 - 1.3 8.2 9.2 1.4 8.0 9.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 GAM24508.1 - 1.4 6.7 9.2 1.6 6.5 9.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 GAM24508.1 - 1.7 9.1 13.9 4.8 7.6 13.8 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) LMBR1 PF04791.16 GAM24508.1 - 1.8 7.4 7.2 1.8 7.4 7.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein ZapB PF06005.12 GAM24508.1 - 2 8.9 13.7 10 6.7 13.7 2.1 1 1 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 GAM24508.1 - 2.5 8.4 8.5 1.5 9.1 0.3 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 GAM24508.1 - 2.8 8.4 14.1 5.8 7.4 0.7 3.0 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 GAM24508.1 - 3.3 7.8 14.7 4.2 7.4 14.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cep57_CLD_2 PF14197.6 GAM24508.1 - 3.3 7.9 10.6 4.4 7.5 4.4 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DASH_Dam1 PF08653.10 GAM24508.1 - 3.8 7.4 6.3 19 5.2 0.2 2.7 1 1 2 3 3 3 0 DASH complex subunit Dam1 DUF4407 PF14362.6 GAM24508.1 - 3.9 6.8 9.7 5.5 6.2 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 GAM24508.1 - 4.3 8.0 12.9 7 7.3 0.8 3.1 1 1 1 3 3 3 0 SlyX Fib_alpha PF08702.10 GAM24508.1 - 5.9 7.1 15.0 10 6.3 14.9 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ACCA PF03255.14 GAM24508.1 - 6.9 6.5 10.4 4.2 7.3 6.7 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Swi5 PF07061.11 GAM24508.1 - 7.7 6.7 14.3 1.2e+02 2.8 11.0 2.9 1 1 1 2 2 2 0 Swi5 Rhodanese PF00581.20 GAM24509.1 - 0.00025 21.5 0.0 0.00045 20.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain zf-C3H1 PF10650.9 GAM24510.1 - 0.00011 21.8 1.1 0.00019 21.1 1.1 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain DUF3439 PF11921.8 GAM24510.1 - 2.9 7.9 18.2 0.43 10.6 3.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Vps51 PF08700.11 GAM24512.1 - 2.6e-12 46.6 1.9 2.6e-12 46.6 1.9 3.0 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 GAM24512.1 - 0.79 9.9 9.0 0.18 11.9 0.3 3.8 3 1 0 3 3 3 0 Golgi transport complex subunit 5 BNIP2 PF12496.8 GAM24512.1 - 1.3 9.4 5.1 1.1 9.7 0.0 3.3 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 E2F_TDP PF02319.20 GAM24513.1 - 1.5e-16 60.2 1.0 1.2e-07 31.6 0.3 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DUF4923 PF16270.5 GAM24513.1 - 0.48 10.2 2.6 0.24 11.2 0.3 1.6 2 0 0 2 2 2 0 Lipocalin-like domain (DUF4923) ABA_GPCR PF12430.8 GAM24514.1 - 8.8e-39 133.1 7.6 8.8e-39 133.1 7.6 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 GAM24514.1 - 4.4e-21 74.7 0.2 1.4e-20 73.1 0.1 1.9 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Ribosomal_S7e PF01251.18 GAM24514.1 - 0.039 13.7 0.5 0.074 12.8 0.2 1.5 1 1 0 1 1 1 0 Ribosomal protein S7e K-box PF01486.17 GAM24514.1 - 0.16 12.2 4.1 0.35 11.1 1.1 2.2 2 0 0 2 2 2 0 K-box region fn3 PF00041.21 GAM24515.1 - 2.5e-06 27.7 13.0 3.8e-05 24.0 3.9 3.8 3 1 0 3 3 3 2 Fibronectin type III domain RGI_lyase PF18370.1 GAM24515.1 - 0.066 13.5 0.5 0.19 12.1 0.5 1.7 1 0 0 1 1 1 0 Rhamnogalacturonan I lyases beta-sheet domain Rhodanese PF00581.20 GAM24516.1 - 7.4e-13 49.0 0.0 2e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain SRP68 PF16969.5 GAM24518.1 - 6.4e-105 352.3 12.7 7.3e-105 352.1 12.7 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 DUF4709 PF15821.5 GAM24518.1 - 0.033 14.5 0.7 0.17 12.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) ACP_PD PF04336.12 GAM24518.1 - 0.033 14.6 0.3 0.53 10.7 0.1 2.6 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase SfLAP PF11139.8 GAM24518.1 - 0.16 11.4 0.3 0.3 10.5 0.3 1.4 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein Peroxin-3 PF04882.12 GAM24519.1 - 2.5e-23 82.8 3.3 9.6e-22 77.6 3.3 2.2 1 1 0 1 1 1 1 Peroxin-3 DUF5411 PF17424.2 GAM24519.1 - 0.0026 17.7 0.1 0.0069 16.4 0.1 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5411) CSTF_C PF14304.6 GAM24519.1 - 0.031 13.9 1.1 9 6.0 0.0 3.0 2 1 0 2 2 2 0 Transcription termination and cleavage factor C-terminal PH_3 PF14593.6 GAM24520.1 - 1.8e-15 56.9 0.8 4.6e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 PH domain PH PF00169.29 GAM24520.1 - 3.2e-07 30.8 0.5 8.9e-07 29.4 0.1 2.1 2 0 0 2 2 2 1 PH domain Lip_prot_lig_C PF10437.9 GAM24520.1 - 0.033 14.2 0.2 0.09 12.8 0.2 1.7 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus PH_6 PF15406.6 GAM24520.1 - 0.035 14.4 0.0 0.22 11.8 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain HLH PF00010.26 GAM24520.1 - 0.067 13.2 3.8 0.18 11.8 1.8 2.7 3 0 0 3 3 3 0 Helix-loop-helix DNA-binding domain Mre11_DNA_bind PF04152.14 GAM24521.1 - 7.4e-39 133.8 0.2 2.6e-38 132.0 0.0 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 GAM24521.1 - 1.3e-14 55.2 2.3 2.8e-14 54.1 2.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_M18 PF02127.15 GAM24522.1 - 1e-150 502.3 0.0 4.1e-150 500.4 0.0 1.8 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 GAM24522.1 - 7.2e-06 25.2 0.1 0.00086 18.4 0.1 2.3 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase zf-UBR PF02207.20 GAM24523.1 - 5.6e-09 36.0 12.1 5.6e-09 36.0 12.1 3.1 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-C3HC4_2 PF13923.6 GAM24523.1 - 0.00095 19.0 0.5 0.00095 19.0 0.5 3.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM24523.1 - 0.0022 17.9 0.6 0.0022 17.9 0.6 4.2 4 1 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAM24523.1 - 0.013 15.4 0.9 0.013 15.4 0.9 3.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF3439 PF11921.8 GAM24523.1 - 8 6.5 29.4 1.4 8.9 14.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Methyltransf_23 PF13489.6 GAM24524.1 - 9.9e-08 32.0 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM24524.1 - 8e-07 29.7 0.0 2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM24524.1 - 4e-06 27.5 0.9 8.7e-05 23.2 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM24524.1 - 0.00013 21.8 0.0 0.00033 20.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM24524.1 - 0.00015 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 GAM24524.1 - 0.0038 17.9 0.0 0.011 16.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 GAM24524.1 - 0.036 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase TehB PF03848.14 GAM24524.1 - 0.053 12.9 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB KIF1B PF12423.8 GAM24524.1 - 0.067 13.6 0.0 0.26 11.7 0.0 2.1 1 0 0 1 1 1 0 Kinesin protein 1B Methyltransf_32 PF13679.6 GAM24524.1 - 0.11 12.4 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain YcxB PF14317.6 GAM24524.1 - 0.15 11.8 0.1 0.8 9.4 0.0 2.3 2 0 0 2 2 2 0 YcxB-like protein Mto2_bdg PF12808.7 GAM24525.1 - 0.68 10.3 12.8 0.054 13.8 6.9 2.1 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Tsc35 PF15079.6 GAM24525.1 - 0.92 9.1 8.6 1.4 8.4 8.6 1.2 1 0 0 1 1 1 0 Testis-specific protein 35 DUF5094 PF17015.5 GAM24525.1 - 1.1 9.4 9.4 2 8.5 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) CRT-like PF08627.10 GAM24526.1 - 4e-145 482.9 22.7 4.8e-145 482.7 22.7 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 GAM24526.1 - 9.2e-09 35.2 4.0 9.2e-09 35.2 4.0 2.3 2 0 0 2 2 2 1 Solute carrier family 35 EamA PF00892.20 GAM24526.1 - 0.00025 21.2 12.3 0.00025 21.2 12.3 3.2 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 GAM24526.1 - 0.00053 19.3 7.7 0.00053 19.3 7.7 2.1 2 0 0 2 2 2 1 UAA transporter family TIG PF01833.24 GAM24527.1 - 2e-06 27.8 51.5 0.00055 20.0 1.2 8.1 5 2 1 7 7 7 5 IPT/TIG domain GTP_EFTU PF00009.27 GAM24528.1 - 4e-22 78.7 0.2 6.1e-21 74.9 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM24528.1 - 1.9e-20 73.3 0.1 5e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAM24528.1 - 0.0001 22.6 2.0 0.00023 21.5 2.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 GAM24528.1 - 0.034 14.0 1.4 0.034 14.0 1.4 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AAA PF00004.29 GAM24528.1 - 0.087 13.3 2.3 13 6.2 0.0 3.0 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) RhoGEF PF00621.20 GAM24529.1 - 6.2e-51 173.2 3.8 6.2e-51 173.2 3.8 2.9 4 1 0 4 4 4 1 RhoGEF domain IQ PF00612.27 GAM24529.1 - 4.4e-05 22.9 0.6 0.00013 21.5 0.6 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH PF00169.29 GAM24529.1 - 0.0001 22.8 2.0 0.00014 22.3 0.0 2.3 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 GAM24529.1 - 0.0013 18.7 0.1 0.006 16.6 0.1 2.1 1 0 0 1 1 1 1 PH domain CDC45 PF02724.14 GAM24529.1 - 0.062 11.6 18.3 0.13 10.5 18.3 1.5 1 0 0 1 1 1 0 CDC45-like protein Androgen_recep PF02166.16 GAM24529.1 - 2.8 6.7 9.3 4.3 6.1 9.3 1.3 1 0 0 1 1 1 0 Androgen receptor KCNQ2_u3 PF16642.5 GAM24529.1 - 7.9 7.6 8.6 3.4 8.7 5.1 2.3 1 1 1 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 FSH1 PF03959.13 GAM24530.1 - 1e-47 162.6 0.1 1.9e-47 161.7 0.1 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF924 PF06041.11 GAM24530.1 - 3.8e-39 134.7 0.6 8.4e-39 133.6 0.3 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF924) LRR_6 PF13516.6 GAM24530.1 - 1.9e-10 39.9 28.7 0.07 13.2 0.2 9.6 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.33 GAM24530.1 - 0.078 13.6 6.3 29 5.8 0.0 5.7 7 0 0 7 7 7 0 Leucine Rich Repeat SpoU_sub_bind PF08032.12 GAM24530.1 - 0.12 12.7 0.0 19 5.6 0.0 3.1 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding zf-C4H2 PF10146.9 GAM24530.1 - 0.14 12.4 0.5 0.38 11.0 0.5 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein TPR_1 PF00515.28 GAM24531.1 - 2.3e-16 58.8 16.9 2.1e-07 30.5 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAM24531.1 - 1.7e-13 49.5 15.3 0.00037 20.4 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM24531.1 - 1e-09 38.5 9.7 8.8e-05 22.7 0.3 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM24531.1 - 6.8e-09 36.2 4.9 0.01 16.5 0.2 4.4 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM24531.1 - 1e-08 34.7 6.4 0.0077 16.4 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM24531.1 - 1.2e-07 32.0 7.7 0.0082 16.9 0.0 4.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM24531.1 - 1.5e-07 31.3 4.5 4.5e-05 23.5 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM24531.1 - 3.1e-06 27.3 6.1 0.0093 16.1 1.1 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM24531.1 - 1.5e-05 24.6 6.7 0.014 15.1 0.4 4.3 4 0 0 4 4 4 2 TPR repeat TPR_6 PF13174.6 GAM24531.1 - 4.1e-05 23.9 14.0 0.0061 17.1 0.0 6.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM24531.1 - 4.3e-05 23.9 12.5 0.063 13.8 3.0 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM24531.1 - 0.069 13.2 9.6 2 8.6 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM24531.1 - 0.092 13.0 7.7 3.4 8.0 0.4 3.2 3 2 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Serglycin PF04360.12 GAM24531.1 - 0.25 11.3 4.3 0.14 12.1 1.9 1.7 2 0 0 2 2 2 0 Serglycin rve_2 PF13333.6 GAM24531.1 - 0.27 11.5 2.8 2.9 8.1 0.1 2.7 2 0 0 2 2 2 0 Integrase core domain TPR_10 PF13374.6 GAM24531.1 - 0.4 10.6 12.8 3.2 7.7 1.1 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat HLH PF00010.26 GAM24532.1 - 0.0011 18.9 0.4 0.0034 17.3 0.4 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 GAM24533.1 - 2.2e-29 102.5 30.1 2.7e-28 98.9 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAM24533.1 - 8.5e-18 64.1 11.5 8.5e-18 64.1 11.5 1.9 1 1 1 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 GAM24533.1 - 4.9e-08 32.4 10.3 1.4e-06 27.6 5.1 2.7 2 2 0 2 2 2 2 PUCC protein Sugar_tr PF00083.24 GAM24533.1 - 2e-07 30.2 22.5 8.1e-05 21.7 11.1 2.4 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 GAM24533.1 - 0.09 11.2 6.4 0.16 10.4 5.3 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector PI3_PI4_kinase PF00454.27 GAM24534.1 - 7.9e-41 140.5 0.3 8.6e-30 104.4 0.2 3.0 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAM24534.1 - 7.6e-24 84.1 0.1 2.1e-23 82.7 0.1 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Carbpep_Y_N PF05388.11 GAM24534.1 - 0.091 13.3 0.7 0.39 11.3 0.7 2.1 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide Pyr_redox_2 PF07992.14 GAM24535.1 - 8.8e-57 192.6 0.0 1.1e-56 192.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM24535.1 - 2.4e-11 44.0 0.0 2.6e-09 37.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase IF-2 PF11987.8 GAM24535.1 - 0.085 13.0 0.0 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 Translation-initiation factor 2 DAO PF01266.24 GAM24535.1 - 0.12 12.0 0.0 0.31 10.6 0.0 1.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase Ras PF00071.22 GAM24536.1 - 1.2e-14 54.2 0.8 3.4e-06 26.8 0.0 2.7 3 0 0 3 3 3 2 Ras family Roc PF08477.13 GAM24536.1 - 3.4e-10 40.2 5.4 6.9e-06 26.3 0.0 3.6 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24536.1 - 1.5e-07 31.0 0.1 0.0097 15.4 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Secretin_N_2 PF07655.13 GAM24536.1 - 0.0053 17.3 5.6 0.0053 17.3 5.6 6.6 4 2 2 6 6 6 1 Secretin N-terminal domain MMR_HSR1 PF01926.23 GAM24536.1 - 0.18 11.9 5.1 0.1 12.7 0.4 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 GAM24536.1 - 1.1 9.5 10.5 1 9.6 0.1 3.4 4 0 0 4 4 4 0 AAA domain Med2 PF11214.8 GAM24536.1 - 6.1 7.1 18.6 0.28 11.4 2.2 4.3 4 0 0 4 4 4 0 Mediator complex subunit 2 Filament PF00038.21 GAM24537.1 - 0.0076 15.9 43.9 0.1 12.1 10.5 4.0 2 1 1 3 3 3 3 Intermediate filament protein DUF2048 PF09752.9 GAM24537.1 - 1.5 7.8 8.7 0.12 11.5 3.6 1.7 2 0 0 2 2 2 0 Abhydrolase domain containing 18 DUF948 PF06103.11 GAM24537.1 - 5.9 7.2 24.9 0.41 10.9 4.2 4.9 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF543 PF04418.12 GAM24538.1 - 0.021 14.8 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF543) DUF2207 PF09972.9 GAM24538.1 - 8 5.1 7.8 8.9 4.9 7.8 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FNIP PF05725.12 GAM24539.1 - 2e-47 159.1 23.3 9.7e-12 44.9 0.5 7.1 2 1 0 6 6 6 5 FNIP Repeat DUF3987 PF13148.6 GAM24539.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Apt1 PF10351.9 GAM24539.1 - 2.6 6.8 11.9 3.5 6.4 11.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 GAM24539.1 - 6.4 6.6 13.7 9.3 6.1 13.7 1.1 1 0 0 1 1 1 0 SPX domain PIG-L PF02585.17 GAM24540.1 - 1.7e-28 99.8 0.0 2.5e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF364 PF04016.12 GAM24540.1 - 0.16 11.6 0.1 0.54 9.8 0.0 1.8 3 0 0 3 3 3 0 Putative heavy-metal chelation zf-C3HC4_3 PF13920.6 GAM24541.1 - 6.9e-10 38.6 5.8 1.1e-09 38.0 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM24541.1 - 4.2e-09 36.1 6.8 8.9e-09 35.1 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM24541.1 - 1.3e-07 31.3 6.8 2.9e-07 30.3 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM24541.1 - 6.4e-07 29.1 6.5 2.5e-06 27.3 6.7 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAM24541.1 - 6.9e-07 29.5 7.2 1.5e-06 28.4 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAM24541.1 - 3.7e-06 26.8 6.1 8.1e-06 25.7 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM24541.1 - 8.7e-06 25.7 4.1 8.7e-06 25.7 4.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 GAM24541.1 - 0.0033 17.5 4.6 0.01 16.0 4.6 1.8 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 GAM24541.1 - 0.028 14.6 9.0 0.065 13.4 9.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAM24541.1 - 0.079 13.3 5.3 0.34 11.2 5.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 GAM24541.1 - 0.38 10.6 5.9 2.2 8.1 6.3 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 GAM24541.1 - 0.69 9.8 3.3 1.8 8.5 3.3 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 GAM24541.1 - 1.7 8.4 9.3 11 5.8 9.2 2.2 1 1 1 2 2 2 0 P-11 zinc finger Pkinase PF00069.25 GAM24546.1 - 9.2e-69 231.7 0.0 1.9e-68 230.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24546.1 - 2.7e-55 187.5 0.0 5.6e-55 186.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM24546.1 - 7.6e-06 25.0 3.4 7.6e-06 25.0 3.4 3.8 3 2 0 3 3 3 1 Fungal protein kinase Clat_adaptor_s PF01217.20 GAM24547.1 - 4.7e-54 182.2 2.3 5.4e-54 182.0 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ParE_toxin PF05016.15 GAM24547.1 - 0.062 13.9 0.1 0.14 12.8 0.0 1.5 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE polyprenyl_synt PF00348.17 GAM24548.1 - 1.5e-92 309.3 0.0 1.9e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Metallophos PF00149.28 GAM24549.1 - 3.8e-35 122.2 0.0 6.1e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 GAM24549.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Polyketide_cyc2 PF10604.9 GAM24550.1 - 5e-11 43.1 0.1 6e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 GAM24550.1 - 0.095 12.9 0.1 0.13 12.5 0.1 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ABC_membrane PF00664.23 GAM24551.1 - 1.2e-53 182.6 42.2 1.6e-33 116.5 17.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM24551.1 - 4.7e-49 166.4 0.0 6.3e-29 101.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM24551.1 - 4.9e-11 42.5 0.1 0.00019 21.0 0.0 3.6 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAM24551.1 - 0.00011 22.2 0.2 0.022 14.7 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 GAM24551.1 - 0.00011 22.2 1.0 0.33 11.1 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 GAM24551.1 - 0.00067 19.5 0.0 1.4 8.6 0.0 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM24551.1 - 0.0015 18.2 1.4 0.86 9.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 GAM24551.1 - 0.002 17.7 0.1 0.27 10.7 0.1 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 GAM24551.1 - 0.018 14.8 0.0 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 GAM24551.1 - 0.023 15.0 0.6 1.9 8.7 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAM24551.1 - 0.023 15.1 0.5 0.11 12.9 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 GAM24551.1 - 0.028 14.9 8.9 0.25 11.8 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.6 GAM24551.1 - 0.033 13.8 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 GAM24551.1 - 0.063 13.4 0.1 0.063 13.4 0.1 2.3 2 1 1 3 3 3 0 Helicase HerA, central domain T2SSE PF00437.20 GAM24551.1 - 0.068 12.2 0.1 7.4 5.5 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 GAM24551.1 - 0.072 13.6 0.1 8.3 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAM24551.1 - 0.18 11.5 0.0 7.7 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain PAP_assoc PF03828.19 GAM24552.1 - 2.1e-08 34.3 0.9 8.7e-08 32.3 0.9 2.1 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAM24552.1 - 4.6e-06 26.8 0.0 1.1e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAM24552.1 - 0.0004 20.4 0.1 0.0011 19.0 0.1 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase TIG PF01833.24 GAM24553.1 - 0.00011 22.2 3.5 0.00024 21.1 1.7 2.5 2 0 0 2 2 2 1 IPT/TIG domain EGF_2 PF07974.13 GAM24553.1 - 0.00034 20.9 13.7 0.00078 19.8 13.7 1.7 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 GAM24553.1 - 0.011 15.9 6.1 0.011 15.9 6.1 1.9 2 0 0 2 2 2 0 Laminin EGF domain Nucleoporin_N PF08801.11 GAM24554.1 - 1e-52 179.4 3.1 1e-52 179.4 3.1 2.6 2 1 0 2 2 2 1 Nup133 N terminal like IBR PF01485.21 GAM24555.1 - 9.8e-19 67.3 52.9 5e-14 52.3 6.0 4.6 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 GAM24555.1 - 4.1e-06 26.5 2.2 4.1e-06 26.5 2.2 5.1 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM24555.1 - 3.9e-05 23.4 2.9 3.9e-05 23.4 2.9 4.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM24555.1 - 0.00094 19.2 2.6 0.00094 19.2 2.6 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAM24555.1 - 0.001 19.4 5.4 0.001 19.4 5.4 4.7 3 1 1 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.6 GAM24555.1 - 0.011 15.5 3.4 0.011 15.5 3.4 4.1 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 DUF382 PF04037.13 GAM24556.1 - 2.8e-50 169.7 0.5 2.8e-50 169.7 0.5 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 GAM24556.1 - 8.7e-22 76.7 3.7 1.9e-21 75.7 3.7 1.6 1 0 0 1 1 1 1 PSP Astro_capsid_N PF03115.14 GAM24556.1 - 0.044 12.4 10.4 0.081 11.6 10.4 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RabGAP-TBC PF00566.18 GAM24557.1 - 2.7e-22 79.5 6.9 3.8e-14 52.9 0.3 6.7 3 2 2 5 5 5 2 Rab-GTPase-TBC domain Pkinase PF00069.25 GAM24558.1 - 8.7e-68 228.5 0.0 1.3e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24558.1 - 5.9e-53 179.8 0.0 8.3e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM24558.1 - 1.4e-07 30.7 0.0 3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM24558.1 - 0.0054 15.7 0.2 0.13 11.2 0.2 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Abi_2 PF07751.11 GAM24558.1 - 0.018 15.3 2.9 0.069 13.4 0.1 2.3 2 0 0 2 2 2 0 Abi-like protein Nop14 PF04147.12 GAM24558.1 - 0.81 7.8 18.5 1.2 7.3 18.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 GAM24558.1 - 1.2 8.2 23.3 1.7 7.7 23.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 GAM24558.1 - 1.3 8.3 18.8 1.8 7.8 18.8 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAM24558.1 - 2.5 6.3 11.5 3.8 5.7 11.5 1.3 1 0 0 1 1 1 0 CDC45-like protein RasGAP PF00616.19 GAM24559.1 - 4.8e-28 98.3 0.1 1.1e-22 80.7 0.1 5.5 3 2 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase Arf PF00025.21 GAM24560.1 - 1e-46 158.6 0.1 1.2e-46 158.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAM24560.1 - 1.9e-22 79.6 0.0 2.3e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24560.1 - 8.8e-18 64.7 0.0 1.2e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAM24560.1 - 3.5e-12 46.2 0.0 4.7e-12 45.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM24560.1 - 2.9e-10 39.9 0.0 3.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM24560.1 - 5.9e-10 39.2 0.0 8.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAM24560.1 - 2.4e-09 36.9 0.2 4.1e-06 26.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 GAM24560.1 - 0.034 13.6 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 GAM24560.1 - 0.048 13.4 0.0 2.2 8.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 GAM24560.1 - 0.071 13.2 0.3 1.4 9.0 0.3 2.1 1 1 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 GAM24560.1 - 0.083 12.4 1.0 0.15 11.5 0.1 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B DNase_II PF03265.15 GAM24561.1 - 2.1e-66 224.4 9.1 2.7e-66 224.1 9.1 1.1 1 0 0 1 1 1 1 Deoxyribonuclease II DUF3978 PF13123.6 GAM24561.1 - 0.18 11.5 1.2 0.77 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3978) IlvGEDA_leader PF08046.11 GAM24561.1 - 0.93 9.0 2.5 1.7 8.1 2.5 1.4 1 0 0 1 1 1 0 IlvGEDA operon leader peptide EGF_2 PF07974.13 GAM24562.1 - 0.081 13.3 12.6 0.19 12.1 12.6 1.6 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 GAM24562.1 - 6 7.3 10.0 15 6.0 10.0 1.7 1 0 0 1 1 1 0 EGF-like domain LRR_1 PF00560.33 GAM24562.1 - 6.3 7.8 7.4 4.7 8.1 0.2 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Hydrolase_4 PF12146.8 GAM24563.1 - 1.8e-66 223.9 0.0 2.2e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM24563.1 - 5.6e-13 49.1 0.2 1e-10 41.7 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM24563.1 - 7.2e-12 46.4 0.0 1e-11 45.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GAM24563.1 - 8.3e-05 22.5 0.1 3.4 7.4 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAM24563.1 - 0.00015 21.3 0.4 0.013 14.9 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 GAM24563.1 - 0.00041 20.1 0.0 0.0015 18.2 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 GAM24563.1 - 0.00045 20.0 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 GAM24563.1 - 0.003 17.7 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PhoPQ_related PF10142.9 GAM24563.1 - 0.009 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_3 PF07859.13 GAM24563.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 GAM24563.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.12 GAM24563.1 - 0.058 12.1 0.1 0.48 9.1 0.0 2.1 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 GAM24563.1 - 0.15 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.13 GAM24563.1 - 0.22 10.0 0.2 24 3.3 0.0 2.8 3 0 0 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II TFIIA PF03153.13 GAM24564.1 - 0.00028 21.0 25.6 0.00028 21.0 25.6 3.2 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit DUF1461 PF07314.11 GAM24564.1 - 0.24 11.3 1.7 0.61 10.0 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) CCSAP PF15748.5 GAM24564.1 - 1.1 9.3 55.9 1.6 8.9 19.2 3.5 3 0 0 3 3 3 0 Centriole, cilia and spindle-associated Methyltransf_23 PF13489.6 GAM24565.1 - 2.3e-24 86.1 0.1 5.1e-24 85.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM24565.1 - 0.019 15.6 1.1 0.32 11.7 0.1 3.0 3 1 0 3 3 3 0 Methyltransferase domain Lar_restr_allev PF14354.6 GAM24565.1 - 0.037 14.4 0.6 0.09 13.2 0.6 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Methyltransf_12 PF08242.12 GAM24565.1 - 0.079 13.7 0.9 0.83 10.4 0.0 2.9 3 2 1 4 4 4 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAM24565.1 - 0.12 12.2 0.2 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain zf-Mss51 PF13824.6 GAM24565.1 - 0.16 12.1 2.0 0.37 10.9 2.0 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-piccolo PF05715.13 GAM24565.1 - 0.23 11.6 2.4 0.39 10.9 1.6 1.8 2 0 0 2 2 2 0 Piccolo Zn-finger TF_Zn_Ribbon PF08271.12 GAM24565.1 - 0.28 10.7 1.5 0.68 9.5 1.5 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding SSP160 PF06933.11 GAM24565.1 - 2 6.5 17.8 2.7 6.1 17.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ribonuc_red_lgC PF02867.15 GAM24566.1 - 5.7e-184 612.5 0.0 7.4e-184 612.1 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAM24566.1 - 2.7e-21 75.3 0.0 7.5e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAM24566.1 - 5.9e-14 52.4 0.0 2e-13 50.7 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain FNIP PF05725.12 GAM24567.1 - 3.4e-65 216.0 37.8 1.7e-13 50.5 0.2 9.1 8 1 1 9 9 9 8 FNIP Repeat Glyco_hydro_65C PF03633.15 GAM24567.1 - 0.12 12.3 2.7 12 5.9 0.0 4.3 5 0 0 5 5 5 0 Glycosyl hydrolase family 65, C-terminal domain LRR_4 PF12799.7 GAM24567.1 - 5.7 7.5 16.9 14 6.3 0.2 6.7 4 3 3 7 7 7 0 Leucine Rich repeats (2 copies) Fibroin_P25 PF07294.11 GAM24568.1 - 0.45 10.5 6.5 0.64 10.1 0.1 2.6 3 0 0 3 3 3 0 Fibroin P25 Pentapeptide_4 PF13599.6 GAM24568.1 - 0.54 10.5 11.6 0.17 12.1 0.4 3.6 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) Ank_4 PF13637.6 GAM24570.1 - 5.5e-06 26.8 0.4 2.2 8.9 0.0 7.7 9 0 0 9 9 9 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM24570.1 - 1.6e-05 24.9 10.4 58 4.7 0.0 11.3 14 0 0 14 14 14 1 Ankyrin repeat RNase_T PF00929.24 GAM24571.1 - 9.9e-07 29.5 0.0 5.5e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Exonuclease ZapB PF06005.12 GAM24571.1 - 0.031 14.7 9.1 0.31 11.5 9.1 2.6 1 1 0 1 1 1 0 Cell division protein ZapB Sec20 PF03908.13 GAM24571.1 - 0.058 13.3 1.1 0.33 10.9 1.1 2.4 1 0 0 1 1 1 0 Sec20 Fez1 PF06818.15 GAM24571.1 - 0.11 13.0 3.0 0.27 11.6 3.0 1.7 1 0 0 1 1 1 0 Fez1 UPF0242 PF06785.11 GAM24571.1 - 0.12 12.4 6.2 0.27 11.3 6.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 GAM24571.1 - 0.14 12.4 6.5 0.087 13.1 2.9 2.7 2 0 0 2 2 1 0 Homeobox associated leucine zipper GvpL_GvpF PF06386.11 GAM24571.1 - 0.26 11.2 1.4 0.55 10.1 1.4 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_1 PF00170.21 GAM24571.1 - 0.29 11.3 5.3 0.27 11.4 1.7 2.5 1 1 1 2 2 2 0 bZIP transcription factor Mod_r PF07200.13 GAM24571.1 - 0.31 11.1 9.0 1 9.5 9.0 1.9 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Jnk-SapK_ap_N PF09744.9 GAM24571.1 - 0.42 10.8 6.9 1.4 9.1 6.9 1.9 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Shugoshin_N PF07558.11 GAM24571.1 - 0.51 10.2 4.6 1.8 8.5 0.1 3.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Rootletin PF15035.6 GAM24571.1 - 0.59 10.1 9.5 0.47 10.5 7.0 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cnn_1N PF07989.11 GAM24571.1 - 0.62 10.3 7.1 3.6 7.8 7.1 2.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 TMPIT PF07851.13 GAM24571.1 - 1.1 8.5 3.2 2.1 7.5 3.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF812 PF05667.11 GAM24571.1 - 1.3 7.8 8.9 0.35 9.7 4.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) NRBF2 PF08961.10 GAM24571.1 - 1.6 8.3 12.7 2.2 7.8 9.2 2.6 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Ax_dynein_light PF10211.9 GAM24571.1 - 1.8 8.5 8.0 21 5.0 6.6 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain YabA PF06156.13 GAM24571.1 - 1.9 9.2 12.9 1.1 9.9 8.4 2.5 2 0 0 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 GAM24571.1 - 2 8.2 8.4 10 6.0 2.7 2.8 1 1 1 2 2 2 0 Septum formation initiator NOA36 PF06524.12 GAM24571.1 - 2.5 7.3 13.9 16 4.7 14.8 1.8 2 0 0 2 2 2 0 NOA36 protein Sec7 PF01369.20 GAM24574.1 - 2.9e-62 209.6 0.9 5.5e-62 208.7 0.9 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 GAM24574.1 - 2.1e-12 47.4 3.5 2e-08 34.7 0.2 3.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 GAM24574.1 - 0.0036 17.7 6.6 0.088 13.2 0.1 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain HAD_2 PF13419.6 GAM24575.1 - 3.7e-07 30.4 0.1 5.3e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Motile_Sperm PF00635.26 GAM24575.1 - 0.046 13.6 0.3 0.61 10.0 0.0 2.5 3 0 0 3 3 3 0 MSP (Major sperm protein) domain Trans_reg_C PF00486.28 GAM24575.1 - 0.15 12.2 0.1 0.7 10.0 0.0 2.1 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal NAPRTase_N PF17767.1 GAM24576.1 - 2.6e-38 131.2 0.0 7.1e-38 129.8 0.0 1.8 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 GAM24576.1 - 1.2e-32 112.6 0.0 2.1e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 GAM24576.1 - 2e-08 34.2 0.0 7.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family UCH PF00443.29 GAM24578.1 - 4e-76 255.9 0.1 5e-76 255.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM24578.1 - 1.6e-09 37.8 1.0 0.058 13.0 0.2 3.6 3 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAM24579.1 - 1.2e-18 67.5 0.0 3e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 DUSP domain Pex14_N PF04695.13 GAM24579.1 - 6.2 7.5 9.1 2.1 9.0 5.6 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kelch_6 PF13964.6 GAM24580.1 - 3e-15 55.9 2.6 0.00027 21.1 0.0 3.9 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAM24580.1 - 2.8e-11 43.3 3.0 0.015 15.3 0.1 3.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM24580.1 - 2.8e-10 39.6 3.3 0.0032 17.0 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 GAM24580.1 - 1.5e-08 34.7 0.2 0.82 10.0 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM24580.1 - 0.00053 19.9 0.6 6.6 6.9 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 GAM24580.1 - 0.0017 18.3 1.7 1.5 8.9 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Cullin_binding PF03556.15 GAM24581.1 - 1.8e-28 99.4 0.8 2.8e-28 98.8 0.4 1.5 2 0 0 2 2 2 1 Cullin binding HMA PF00403.26 GAM24582.1 - 2.9e-12 46.9 1.4 3.8e-12 46.5 1.4 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 GAM24582.1 - 0.014 15.7 0.1 0.036 14.4 0.0 1.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Mo25 PF08569.11 GAM24583.1 - 2.6e-132 441.2 19.8 2.9e-132 441.0 19.8 1.0 1 0 0 1 1 1 1 Mo25-like ECH_2 PF16113.5 GAM24583.1 - 0.11 12.0 0.4 0.25 10.8 0.4 1.6 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF2408 PF10303.9 GAM24583.1 - 1.4 9.5 5.9 0.23 12.0 1.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) VPS9 PF02204.18 GAM24584.1 - 6.8e-29 100.1 0.1 2.4e-28 98.4 0.1 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 GAM24584.1 - 5.4e-19 68.3 4.9 1.3e-18 67.1 0.7 2.9 2 1 0 2 2 2 1 PX domain Ras PF00071.22 GAM24584.1 - 5.7e-10 39.0 0.0 1.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Ras family DUF5601 PF18151.1 GAM24584.1 - 0.002 18.4 1.9 0.028 14.7 0.2 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) Roc PF08477.13 GAM24584.1 - 0.003 17.7 0.0 0.0088 16.3 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DMA PF03474.14 GAM24584.1 - 0.35 10.5 1.3 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 DMRTA motif RED_N PF07808.13 GAM24585.1 - 3.6e-21 75.8 1.8 3.6e-21 75.8 1.8 4.5 2 1 2 4 4 4 2 RED-like protein N-terminal region Ras PF00071.22 GAM24586.1 - 1.1e-50 171.4 0.1 1.3e-50 171.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24586.1 - 9.1e-18 64.6 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24586.1 - 6.3e-10 38.8 0.0 8.4e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM24586.1 - 6.5e-06 25.8 0.0 1.6e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM24586.1 - 3.1e-05 23.9 0.1 0.036 14.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAM24586.1 - 0.0017 17.9 0.0 0.012 15.2 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 GAM24586.1 - 0.004 17.2 0.0 0.006 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAM24586.1 - 0.0084 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RhoGAP PF00620.27 GAM24587.1 - 2e-36 125.1 0.3 4.6e-36 123.9 0.3 1.6 1 0 0 1 1 1 1 RhoGAP domain BAR_3 PF16746.5 GAM24587.1 - 0.00024 20.9 2.0 0.00024 20.9 2.0 2.3 2 1 0 2 2 2 1 BAR domain of APPL family BAR PF03114.18 GAM24587.1 - 0.0006 19.5 1.4 0.056 13.1 0.7 2.3 1 1 1 2 2 2 2 BAR domain CENP-F_leu_zip PF10473.9 GAM24587.1 - 0.03 14.3 1.9 0.063 13.3 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Linker_histone PF00538.19 GAM24587.1 - 0.041 14.3 0.9 0.12 12.7 0.9 1.8 1 0 0 1 1 1 0 linker histone H1 and H5 family DUF643 PF04867.12 GAM24587.1 - 4.8 7.8 7.0 0.59 10.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF643) Ank_3 PF13606.6 GAM24588.1 - 0.0022 18.3 0.0 0.31 11.7 0.0 3.8 4 1 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 GAM24588.1 - 0.0094 16.5 0.0 0.55 10.9 0.0 2.9 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAM24588.1 - 0.053 14.0 0.1 27 5.4 0.0 3.2 2 1 0 2 2 2 0 Ankyrin repeat MapZ_C2 PF18708.1 GAM24588.1 - 0.16 12.3 0.0 1.5 9.1 0.0 2.1 1 1 1 2 2 2 0 MapZ extracellular C-terminal domain 2 Ocnus PF05005.15 GAM24590.1 - 1.9e-10 40.9 0.2 4.7e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Janus/Ocnus family (Ocnus) CENP-B_dimeris PF09026.10 GAM24590.1 - 0.0034 17.7 1.7 0.0057 17.0 1.7 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain RXT2_N PF08595.11 GAM24590.1 - 0.0057 16.7 0.7 0.0086 16.1 0.7 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 GAM24590.1 - 0.19 11.4 3.5 0.25 11.1 3.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ank_4 PF13637.6 GAM24591.1 - 7.9e-17 61.4 0.2 2.1e-09 37.8 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM24591.1 - 1.7e-12 47.8 0.1 4.1e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM24591.1 - 2.4e-12 46.8 0.9 1.2e-08 35.1 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAM24591.1 - 5.2e-12 45.6 0.9 1.1e-08 35.1 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 GAM24591.1 - 2.2e-11 42.9 0.7 0.00013 22.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat RA PF00788.23 GAM24591.1 - 6.5e-07 29.9 0.0 9.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Sigma70_r4 PF04545.16 GAM24592.1 - 0.051 13.1 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 L51_S25_CI-B8 PF05047.16 GAM24594.1 - 1.5e-11 44.0 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pkinase PF00069.25 GAM24595.1 - 2.3e-36 125.5 0.6 1e-20 74.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24595.1 - 1.4e-11 44.2 0.1 7.7e-08 31.9 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 GAM24595.1 - 0.00024 20.5 0.1 0.00047 19.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GAM24595.1 - 0.016 14.8 0.2 0.03 13.9 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 GAM24595.1 - 0.08 12.5 0.2 0.26 10.8 0.0 1.9 3 0 0 3 3 3 0 RIO1 family TMEM208_SND2 PF05620.11 GAM24596.1 - 6.2e-48 162.7 0.3 7e-48 162.6 0.3 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF2663 PF10864.8 GAM24596.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) Beta-lactamase2 PF13354.6 GAM24597.1 - 3.1e-22 79.2 0.0 2.1e-21 76.4 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase enzyme family CRIM PF16978.5 GAM24598.1 - 0.0013 18.8 0.4 0.055 13.6 0.0 3.1 3 1 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 GAM24598.1 - 0.044 14.0 3.5 2.2 8.6 3.5 2.8 1 1 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology ubiquitin PF00240.23 GAM24598.1 - 0.11 12.3 0.2 5.7 6.8 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin family LRR_4 PF12799.7 GAM24599.1 - 4.8e-12 45.9 41.5 8.2e-05 22.9 0.8 8.4 4 3 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM24599.1 - 1.1e-11 44.3 33.5 1.4e-05 24.7 5.3 5.8 5 1 0 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 GAM24599.1 - 2.1e-09 36.7 39.0 0.019 15.0 0.2 10.2 12 0 0 12 12 12 6 Leucine Rich repeat RhoGEF PF00621.20 GAM24602.1 - 5e-50 170.3 3.3 1.1e-49 169.2 3.3 1.6 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 GAM24602.1 - 1.2e-17 63.8 12.7 2.3e-17 62.9 12.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 GAM24602.1 - 1.3e-12 48.1 2.9 2.4e-12 47.3 0.8 2.2 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 GAM24602.1 - 1.3e-06 28.4 0.3 2.7e-06 27.4 0.3 1.5 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 GAM24602.1 - 0.0028 17.5 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 GAM24602.1 - 0.0052 16.6 9.2 0.0081 16.0 3.3 3.5 2 2 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 GAM24602.1 - 0.016 15.3 0.5 0.06 13.5 0.5 1.9 1 0 0 1 1 1 0 PH domain Dynamin_N PF00350.23 GAM24603.1 - 2.1e-16 60.4 2.5 3e-16 59.9 0.1 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAM24603.1 - 1.3e-06 28.5 0.0 5.3e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 GAM24603.1 - 0.01 16.4 16.0 0.018 15.5 0.0 4.1 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 GAM24603.1 - 0.025 14.3 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM24603.1 - 0.026 14.4 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 GAM24603.1 - 0.051 14.1 0.0 0.051 14.1 0.0 3.3 4 0 0 4 4 4 0 ABC transporter IstB_IS21 PF01695.17 GAM24603.1 - 0.058 13.1 0.0 2.2 8.0 0.0 2.4 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 GAM24603.1 - 0.21 11.7 3.6 2.2 8.4 0.0 3.8 3 1 0 3 3 3 0 AAA domain SR-25 PF10500.9 GAM24603.1 - 1.6 8.3 16.9 1.3 8.6 1.7 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein 7tm_2 PF00002.24 GAM24604.1 - 3.5e-26 92.0 12.4 4.5e-26 91.6 12.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 GAM24604.1 - 1.3e-20 73.7 8.3 2.2e-20 73.0 8.3 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Frizzled PF01534.17 GAM24604.1 - 1.3e-09 37.5 22.1 3.4e-06 26.4 5.1 2.9 1 1 2 3 3 3 3 Frizzled/Smoothened family membrane region Ocular_alb PF02101.15 GAM24604.1 - 2.7e-08 33.2 9.5 2.7e-08 33.2 9.5 2.1 2 1 0 3 3 3 1 Ocular albinism type 1 protein SR-25 PF10500.9 GAM24605.1 - 0.082 12.5 20.5 0.054 13.1 16.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Miga PF10265.9 GAM24605.1 - 0.92 8.4 11.4 0.51 9.3 9.7 1.4 1 1 0 1 1 1 0 Mitoguardin DNA_pol_phi PF04931.13 GAM24605.1 - 2.4 6.1 14.9 3.3 5.7 14.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 GAM24605.1 - 2.9 6.3 10.4 4.2 5.8 10.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MCM PF00493.23 GAM24606.1 - 4.5e-72 241.8 0.1 8.1e-72 240.9 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAM24606.1 - 1.6e-20 73.2 0.7 3.6e-20 72.1 0.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAM24606.1 - 8.9e-18 64.5 0.4 1.8e-17 63.5 0.4 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 GAM24606.1 - 1.2e-07 31.3 0.2 0.00034 20.1 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAM24606.1 - 8e-07 29.1 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 GAM24606.1 - 0.007 16.8 0.3 0.035 14.5 0.1 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAM24606.1 - 0.013 15.3 0.1 0.22 11.2 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 GAM24606.1 - 0.045 13.5 0.3 0.09 12.5 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAM24606.1 - 0.07 13.5 0.2 0.21 11.9 0.2 1.8 1 0 0 1 1 1 0 AAA ATPase domain VWC PF00093.18 GAM24607.1 - 3.1 8.2 6.8 10 6.5 0.3 2.5 2 0 0 2 2 2 0 von Willebrand factor type C domain zf-C3HC4_3 PF13920.6 GAM24608.1 - 1.7e-09 37.3 6.5 3.1e-09 36.5 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM24608.1 - 6.4e-07 29.6 8.7 1.4e-06 28.6 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAM24608.1 - 1.7e-06 27.9 8.5 0.0011 19.0 2.7 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 GAM24608.1 - 3.6e-06 26.7 4.6 7.7e-05 22.5 5.4 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM24608.1 - 5.2e-06 26.3 7.1 1.6e-05 24.8 7.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM24608.1 - 5.9e-06 26.0 6.8 5.9e-06 26.0 6.8 2.0 2 1 1 3 3 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM24608.1 - 4.8e-05 23.1 7.7 0.00011 22.0 7.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAM24608.1 - 0.0013 18.8 7.1 0.01 16.0 1.8 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FHIPEP PF00771.20 GAM24608.1 - 0.0078 14.7 0.0 0.0078 14.7 0.0 1.7 2 0 0 2 2 2 1 FHIPEP family DUF743 PF05332.11 GAM24608.1 - 0.063 13.3 1.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF743) zf-RING_6 PF14835.6 GAM24608.1 - 0.11 12.4 5.0 0.22 11.4 5.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Phage_int_SAM_6 PF18644.1 GAM24608.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Phage integrase SAM-like domain zf-RING_4 PF14570.6 GAM24608.1 - 0.19 11.5 7.5 0.61 9.9 7.6 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 GAM24608.1 - 0.24 11.5 3.5 0.83 9.7 3.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pex14_N PF04695.13 GAM24608.1 - 0.9 10.2 12.3 2 9.1 3.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-Di19 PF05605.12 GAM24608.1 - 1 9.7 5.4 11 6.4 0.2 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding SPG4 PF17325.2 GAM24608.1 - 1.6 9.8 8.6 0.71 11.0 0.9 2.4 2 0 0 2 2 2 0 Stationary phase protein 4 DUF1980 PF09323.10 GAM24608.1 - 2.6 7.9 9.7 1.3 8.9 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) RecR PF02132.15 GAM24608.1 - 2.7 7.6 6.3 21 4.8 0.1 2.6 2 0 0 2 2 2 0 RecR protein zf-rbx1 PF12678.7 GAM24608.1 - 5.9 7.3 16.7 0.16 12.3 8.8 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain Med15 PF09606.10 GAM24608.1 - 6.4 5.3 39.4 10 4.7 39.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ank_5 PF13857.6 GAM24610.1 - 0.091 13.1 0.1 65 4.0 0.0 4.3 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM24611.1 - 0.0006 20.3 0.0 0.12 13.0 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Cation_efflux PF01545.21 GAM24613.1 - 1.3e-46 158.9 7.1 1.3e-46 158.9 7.1 2.7 2 1 0 2 2 2 1 Cation efflux family RNA_binding PF01877.17 GAM24613.1 - 0.11 12.8 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 RNA binding Fe_hyd_lg_C PF02906.14 GAM24614.1 - 9.1e-79 264.5 0.0 1.4e-78 263.9 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain CABIT PF12736.7 GAM24614.1 - 0.088 12.1 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, NDUF_B7 PF05676.13 GAM24616.1 - 1.5e-31 107.9 3.3 2e-31 107.5 3.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Mitoc_L55 PF09776.9 GAM24616.1 - 0.036 13.8 0.4 0.095 12.4 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 Band_7 PF01145.25 GAM24617.1 - 4e-24 85.6 0.4 6e-24 85.0 0.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 GAM24617.1 - 0.00092 18.4 0.5 0.0012 17.9 0.5 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial SH3_9 PF14604.6 GAM24618.1 - 1.1e-26 92.4 0.9 4.9e-13 48.7 0.3 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAM24618.1 - 5.6e-24 83.5 0.7 1.4e-14 53.4 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 GAM24618.1 - 9.8e-21 73.2 0.2 5.2e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 GAM24618.1 - 2.3e-06 27.8 0.1 8.5e-06 26.0 0.1 2.0 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DIT1_PvcA PF05141.12 GAM24618.1 - 0.53 9.7 6.0 1 8.8 6.0 1.5 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF4407 PF14362.6 GAM24618.1 - 5.5 6.3 8.0 8.6 5.6 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RIFIN PF02009.16 GAM24620.1 - 0.17 11.7 8.9 0.29 11.0 8.9 1.3 1 0 0 1 1 1 0 Rifin Rap_GAP PF02145.15 GAM24621.1 - 4.5e-64 215.4 0.6 3.6e-63 212.5 0.0 2.8 3 0 0 3 3 3 1 Rap/ran-GAP PH PF00169.29 GAM24621.1 - 6.6e-27 94.1 10.7 7.4e-17 61.8 1.1 3.8 3 0 0 3 3 3 3 PH domain PH_6 PF15406.6 GAM24621.1 - 9.6e-06 25.9 0.0 3.2e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAM24621.1 - 6.3e-05 23.3 27.0 0.00044 20.6 3.2 6.0 5 1 1 6 6 6 2 Pleckstrin homology domain PH_9 PF15410.6 GAM24621.1 - 0.026 14.9 1.8 0.15 12.4 1.8 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain PH_10 PF15411.6 GAM24621.1 - 0.031 14.5 2.7 0.094 13.0 0.1 3.2 2 1 1 3 3 3 0 Pleckstrin homology domain BORCS6 PF10157.9 GAM24622.1 - 0.0099 16.1 6.4 0.039 14.2 6.4 2.0 1 1 0 1 1 1 1 BLOC-1-related complex sub-unit 6 RQC PF09382.10 GAM24623.1 - 1.1e-18 67.1 0.2 4.8e-18 65.0 0.1 2.2 2 0 0 2 2 2 1 RQC domain DEAD PF00270.29 GAM24623.1 - 5.8e-18 65.3 0.0 1.8e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM24623.1 - 1e-17 64.5 0.0 1.5e-15 57.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 GAM24623.1 - 2e-14 54.1 2.8 7.2e-14 52.3 2.8 2.1 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 GAM24623.1 - 1.1e-10 41.4 0.0 2.3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 HRDC domain DUF3450 PF11932.8 GAM24623.1 - 0.075 12.3 3.9 0.15 11.3 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-C3HC4_3 PF13920.6 GAM24624.1 - 3.2e-12 46.1 12.1 3.2e-12 46.1 12.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM24624.1 - 0.0003 20.6 11.3 0.00065 19.5 11.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAM24624.1 - 0.0012 19.1 13.3 0.0012 19.1 13.3 2.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 GAM24624.1 - 0.0026 17.6 13.6 0.0026 17.6 13.6 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM24624.1 - 0.0063 16.4 12.1 0.0063 16.4 12.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM24624.1 - 0.0064 16.3 13.8 0.017 15.0 13.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.9 GAM24624.1 - 0.084 13.2 7.6 0.15 12.4 7.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-C3HC4_4 PF15227.6 GAM24624.1 - 0.13 12.4 7.2 1.9 8.7 7.9 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Rhodanese PF00581.20 GAM24625.1 - 4e-10 40.2 0.0 5.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Baculo_11_kDa PF06143.11 GAM24625.1 - 0.055 13.0 0.1 0.098 12.3 0.1 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Ras PF00071.22 GAM24626.1 - 3.6e-33 114.5 0.0 4.4e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24626.1 - 1.8e-16 60.4 0.0 2.7e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24626.1 - 0.00024 20.6 0.1 0.00038 19.9 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM24626.1 - 0.0061 16.1 0.0 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgoMid PF16487.5 GAM24626.1 - 0.09 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Mid domain of argonaute Pkinase PF00069.25 GAM24627.1 - 6.2e-69 232.3 0.0 6.2e-69 232.3 0.0 3.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24627.1 - 1.5e-48 165.4 0.0 1.5e-48 165.4 0.0 2.9 4 0 0 4 4 4 1 Protein tyrosine kinase adh_short_C2 PF13561.6 GAM24629.1 - 2.9e-65 220.1 0.4 3.3e-65 219.9 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAM24629.1 - 5.4e-52 176.1 2.6 6.2e-52 175.9 2.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM24629.1 - 1.4e-13 51.2 0.6 2e-13 50.6 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM24629.1 - 1.7e-05 24.4 0.9 6e-05 22.6 0.9 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM24629.1 - 0.00068 18.7 1.4 0.0036 16.3 1.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAM24629.1 - 0.0048 16.1 0.8 0.0083 15.3 0.8 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein ATP_bind_2 PF03668.15 GAM24629.1 - 0.1 11.9 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family p450 PF00067.22 GAM24630.1 - 8.9e-69 232.4 0.1 1.2e-68 232.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Coiled PF05710.12 GAM24631.1 - 0.02 15.7 0.4 0.021 15.7 0.4 1.2 1 0 0 1 1 1 0 Coiled coil Sec7 PF01369.20 GAM24632.1 - 2.7e-59 199.9 4.8 4.3e-59 199.3 2.6 2.6 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 GAM24632.1 - 2.4e-27 95.8 2.1 2.4e-27 95.8 2.1 4.3 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAM24632.1 - 3.2e-25 87.8 3.6 5.2e-19 67.9 0.1 5.0 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) SUIM_assoc PF16619.5 GAM24632.1 - 0.45 10.6 32.1 0.066 13.3 2.4 4.4 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF853 PF05872.12 GAM24632.1 - 0.91 8.0 4.0 2.3 6.7 4.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SRP14 PF02290.15 GAM24638.1 - 1.7e-23 82.8 1.2 2e-23 82.6 0.2 1.5 1 1 1 2 2 2 1 Signal recognition particle 14kD protein FHA_2 PF17913.1 GAM24639.1 - 2.4e-08 34.1 0.0 5.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain FHA PF00498.26 GAM24639.1 - 0.0021 18.4 0.1 0.0057 17.0 0.1 1.7 1 0 0 1 1 1 1 FHA domain zf-CCHH PF10283.9 GAM24639.1 - 0.01 15.8 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 PBZ domain TAFII28 PF04719.14 GAM24640.1 - 4.8e-33 113.1 0.2 1.1e-32 112.0 0.2 1.6 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Porin_3 PF01459.22 GAM24642.1 - 5.9e-09 35.8 0.2 9.2e-09 35.2 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic porin Fn3_assoc PF13287.6 GAM24643.1 - 9.6e-05 22.5 6.5 2.1 8.5 0.5 5.2 4 0 0 4 4 4 2 Fn3 associated CHB_HEX_C_1 PF13290.6 GAM24643.1 - 0.00079 19.4 19.2 0.12 12.4 0.4 5.7 6 0 0 6 6 6 3 Chitobiase/beta-hexosaminidase C-terminal domain DUF2501 PF10696.9 GAM24643.1 - 0.093 13.0 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) zf-CCHC PF00098.23 GAM24644.1 - 0.012 15.7 21.2 0.042 13.9 1.2 3.7 3 1 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.6 GAM24644.1 - 0.018 15.0 12.8 1.1 9.2 0.5 3.6 2 1 1 3 3 3 0 Zinc knuckle ELMO_CED12 PF04727.13 GAM24645.1 - 4.8e-36 124.5 0.1 1.2e-35 123.2 0.1 1.7 1 0 0 1 1 1 1 ELMO/CED-12 family MyTH4 PF00784.17 GAM24645.1 - 0.021 15.3 0.7 0.27 11.7 0.1 2.9 2 0 0 2 2 2 0 MyTH4 domain RdRP PF05183.12 GAM24646.1 - 3.1e-100 336.5 0.0 2e-60 205.1 0.0 2.2 2 0 0 2 2 2 2 RNA dependent RNA polymerase Helicase_C PF00271.31 GAM24646.1 - 1.1e-18 67.6 0.4 3.6e-18 65.9 0.4 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM24646.1 - 6e-17 62.2 0.0 1.4e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM24646.1 - 7.2e-14 51.9 0.2 2e-13 50.5 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 GAM24646.1 - 0.007 15.1 0.3 0.013 14.2 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 GAM24646.1 - 0.045 13.4 0.1 0.089 12.4 0.1 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase FNIP PF05725.12 GAM24647.1 - 7.1e-58 192.5 14.5 5.5e-12 45.6 0.0 9.2 6 3 1 9 9 9 6 FNIP Repeat LRR_4 PF12799.7 GAM24647.1 - 0.16 12.5 17.8 6.4 7.3 4.9 6.7 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) Presenilin PF01080.17 GAM24648.1 - 1.6 7.4 7.8 3.1 6.5 7.8 1.4 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 GAM24648.1 - 9.9 4.3 12.8 16 3.6 12.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Dimer_Tnp_hAT PF05699.14 GAM24649.1 - 7.7e-13 48.0 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 GAM24649.1 - 0.00034 20.9 0.7 0.001 19.4 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) RVT_1 PF00078.27 GAM24650.1 - 7.2e-24 84.5 0.8 2.1e-23 83.0 0.4 2.0 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 GAM24650.1 - 2.5e-07 31.1 0.1 6.2e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAM24650.1 - 1.4e-05 25.7 0.0 3.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RACo_linker PF17650.1 GAM24650.1 - 0.044 13.6 0.1 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 RACo linker region RVP PF00077.20 GAM24650.1 - 0.046 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 GAM24650.1 - 0.081 12.7 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Aspartyl protease Formyl_trans_N PF00551.19 GAM24652.1 - 0.061 13.1 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 Formyl transferase zf_UBZ PF18439.1 GAM24652.1 - 0.17 11.5 0.2 0.23 11.1 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Plk4_PB1 PF18190.1 GAM24657.1 - 0.095 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 Med16 PF11635.8 GAM24657.1 - 0.1 10.5 0.0 0.12 10.3 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 16 Zip PF02535.22 GAM24658.1 - 0.0079 15.5 0.6 0.018 14.3 0.6 1.6 1 0 0 1 1 1 1 ZIP Zinc transporter YfhD PF14151.6 GAM24658.1 - 0.066 13.4 3.2 0.17 12.0 3.2 1.6 1 0 0 1 1 1 0 YfhD-like protein TT_ORF2 PF02957.15 GAM24658.1 - 0.84 10.6 4.0 1.4 9.8 4.0 1.4 1 0 0 1 1 1 0 TT viral ORF2 UCH PF00443.29 GAM24659.1 - 8e-61 205.8 1.6 1.2e-60 205.2 1.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM24659.1 - 2.2e-14 53.8 14.4 2.2e-14 53.8 14.4 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAM24659.1 - 1.6e-07 31.6 16.6 1.6e-07 31.6 16.6 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 GAM24660.1 - 1.8e-12 47.3 5.0 4.4e-12 46.1 5.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAM24660.1 - 3.3e-09 36.6 4.3 8.5e-09 35.2 4.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM24660.1 - 1e-08 34.9 5.0 2.9e-08 33.4 5.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM24660.1 - 2.3e-08 33.7 2.7 4.4e-08 32.9 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAM24660.1 - 1.1e-07 31.5 1.5 3e-07 30.1 1.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAM24660.1 - 1.8e-07 30.9 5.3 3.7e-07 29.9 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM24660.1 - 5.5e-06 26.3 2.3 2e-05 24.5 2.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAM24660.1 - 5.7e-05 22.9 3.1 0.00016 21.5 3.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAM24660.1 - 0.00097 19.4 6.4 0.00097 19.4 6.4 3.6 3 2 1 4 4 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 GAM24660.1 - 0.01 15.6 6.1 0.019 14.8 6.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GAM24660.1 - 0.85 9.8 5.2 2.6 8.3 5.2 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 GAM24661.1 - 8.9e-61 205.5 0.0 2.2e-60 204.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24661.1 - 1.3e-44 152.5 0.0 5.9e-44 150.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM24661.1 - 0.00056 19.3 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAM24661.1 - 0.002 18.1 0.0 0.0066 16.4 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM24661.1 - 0.0041 16.0 2.5 0.006 15.4 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase PHD PF00628.29 GAM24662.1 - 1.9e-14 53.3 26.0 2.1e-07 30.7 5.0 3.5 3 0 0 3 3 3 3 PHD-finger PRCC PF10253.9 GAM24662.1 - 0.049 14.4 0.2 0.049 14.4 0.2 2.9 2 1 1 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting FANCL_C PF11793.8 GAM24662.1 - 6.9 6.9 20.6 3 8.1 7.5 3.5 2 1 1 3 3 3 0 FANCL C-terminal domain UQ_con PF00179.26 GAM24663.1 - 2.6e-44 150.3 0.0 4.3e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM24663.1 - 0.072 12.8 0.1 0.23 11.2 0.0 2.0 2 1 0 2 2 2 0 Prokaryotic E2 family B Cwf_Cwc_15 PF04889.12 GAM24663.1 - 0.46 10.2 11.7 0.84 9.3 11.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GAM24663.1 - 0.71 8.0 10.6 0.9 7.7 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAM24663.1 - 2.5 7.5 10.3 3.2 7.1 10.3 1.2 1 0 0 1 1 1 0 SDA1 EBV-NA3 PF05009.12 GAM24663.1 - 3.3 7.2 6.4 5.6 6.4 6.4 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF5423 PF17461.2 GAM24663.1 - 7.4 5.3 9.6 0.27 10.0 2.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5423) Macoilin PF09726.9 GAM24663.1 - 8.3 4.8 6.9 11 4.4 6.9 1.2 1 0 0 1 1 1 0 Macoilin family Ribosomal_L29 PF00831.23 GAM24664.1 - 3.2e-14 52.6 2.0 3.2e-14 52.6 2.0 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein YgaB PF14182.6 GAM24664.1 - 0.0055 17.1 2.4 0.13 12.7 0.2 2.6 2 1 1 3 3 3 1 YgaB-like protein Nup54_57_C PF18570.1 GAM24664.1 - 0.028 14.0 2.7 1.3 8.6 0.1 2.6 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Snapin_Pallidin PF14712.6 GAM24664.1 - 0.07 13.5 5.5 0.23 11.9 1.5 2.2 1 1 1 2 2 2 0 Snapin/Pallidin Ins_P5_2-kin PF06090.12 GAM24665.1 - 1.6e-82 277.6 0.3 1.8e-82 277.4 0.3 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Sen15 PF09631.10 GAM24665.1 - 0.044 14.1 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Sen15 protein GrpB PF04229.14 GAM24665.1 - 0.057 13.6 0.3 0.72 10.0 0.0 2.3 2 0 0 2 2 2 0 GrpB protein Zn_ribbon_SprT PF17283.2 GAM24665.1 - 0.082 12.8 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain RicinB_lectin_2 PF14200.6 GAM24666.1 - 9.7e-16 58.3 9.2 2.2e-07 31.5 1.9 5.1 4 2 1 5 5 5 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 GAM24666.1 - 0.035 14.4 6.5 0.32 11.3 0.4 4.2 3 2 0 4 4 4 0 Ricin-type beta-trefoil lectin domain DUF3314 PF11771.8 GAM24668.1 - 0.07 13.3 0.0 0.076 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) Kinesin PF00225.23 GAM24669.1 - 7.8e-108 360.3 2.2 7.8e-108 360.3 2.2 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAM24669.1 - 3.6e-28 98.4 0.1 3.5e-27 95.2 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 GAM24669.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.5 4 1 0 4 4 4 0 AAA domain Nrap_D3 PF17404.2 GAM24669.1 - 0.53 10.4 4.1 0.49 10.5 1.1 2.6 2 0 0 2 2 2 0 Nrap protein domain 3 AAA_16 PF13191.6 GAM24669.1 - 3.4 8.0 0.0 3.4 8.0 0.0 4.1 2 1 1 3 3 3 0 AAA ATPase domain GPP34 PF05719.11 GAM24670.1 - 3.1e-15 56.7 0.0 3.9e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) STT3_PglB_C PF18527.1 GAM24670.1 - 0.48 10.6 3.4 0.57 10.3 0.0 2.6 3 0 0 3 3 3 0 STT3/PglB C-terminal beta-barrel domain zf-UBR PF02207.20 GAM24671.1 - 1.5e-15 57.1 12.6 1.5e-15 57.1 12.6 3.1 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.6 GAM24671.1 - 0.0061 16.5 0.3 0.0061 16.5 0.3 3.5 3 0 0 3 3 3 1 zinc-RING finger domain Dehydrin PF00257.19 GAM24671.1 - 0.049 14.2 0.5 0.095 13.3 0.5 1.3 1 0 0 1 1 1 0 Dehydrin Ras PF00071.22 GAM24672.1 - 2.7e-49 166.9 0.4 3.2e-49 166.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24672.1 - 9e-29 100.1 0.3 2.1e-28 98.9 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24672.1 - 5.4e-19 68.3 0.0 6.4e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM24672.1 - 4.1e-08 32.9 0.1 5.6e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM24672.1 - 2.1e-05 24.6 0.0 5.2e-05 23.3 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM24672.1 - 5.6e-05 22.8 0.1 0.00051 19.6 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAM24672.1 - 0.0059 16.1 0.1 0.014 14.8 0.0 1.7 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 GAM24672.1 - 0.006 16.9 0.0 0.081 13.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 GAM24672.1 - 0.01 15.5 0.5 0.022 14.5 0.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAM24672.1 - 0.015 15.4 0.1 0.068 13.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAM24672.1 - 0.021 14.9 0.0 0.034 14.2 0.0 1.4 1 1 0 1 1 1 0 Dynamin family Exo_endo_phos PF03372.23 GAM24673.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.23 GAM24674.1 - 3.3e-05 23.5 0.1 4.1e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GTP_EFTU PF00009.27 GAM24675.1 - 8.5e-41 139.6 0.0 1.1e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM24675.1 - 1e-26 93.4 0.1 6e-26 90.9 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 GAM24675.1 - 2e-05 24.6 0.0 0.00012 22.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAM24675.1 - 0.0012 18.9 0.1 0.46 10.5 0.0 2.3 1 1 0 2 2 2 2 Dynamin family PduV-EutP PF10662.9 GAM24675.1 - 0.019 14.7 0.2 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D2 PF03144.25 GAM24675.1 - 0.059 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Glyco_hydro_57 PF03065.15 GAM24676.1 - 0.081 12.1 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Ceramidase_alk PF04734.13 GAM24678.1 - 1.3e-221 736.7 0.2 1.5e-221 736.4 0.2 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 GAM24678.1 - 5.8e-52 175.9 0.9 1.1e-51 175.0 0.8 1.6 2 0 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Kinesin PF00225.23 GAM24679.1 - 1.1e-110 369.7 0.0 2.5e-110 368.5 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAM24679.1 - 2.9e-27 95.4 0.6 7.9e-27 94.0 0.6 1.8 1 0 0 1 1 1 1 Microtubule binding IstB_IS21 PF01695.17 GAM24679.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein COMP PF11598.8 GAM24679.1 - 0.23 12.0 4.1 2 9.0 0.1 2.7 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Fib_alpha PF08702.10 GAM24679.1 - 0.57 10.4 12.2 2.5 8.3 4.1 3.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 GAM24679.1 - 2.3 8.3 4.7 0.86 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ResIII PF04851.15 GAM24679.1 - 7.3 6.6 8.5 3.9 7.4 0.2 3.3 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit FapA PF03961.13 GAM24679.1 - 8.7 4.8 15.7 2 7.0 8.1 2.2 1 1 0 2 2 2 0 Flagellar Assembly Protein A Peptidase_M8 PF01457.16 GAM24680.1 - 6.2e-68 229.8 3.0 1e-67 229.1 3.0 1.3 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M15_3 PF08291.11 GAM24683.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.3 1 1 0 1 1 1 0 Peptidase M15 AAA_16 PF13191.6 GAM24684.1 - 0.0014 19.1 0.1 0.01 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 GAM24684.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Bromo_TP_like PF17027.5 GAM24684.1 - 0.49 10.5 3.3 1.2 9.3 3.3 1.6 1 0 0 1 1 1 0 Histone-fold protein DUF3377 PF11857.8 GAM24686.1 - 1.2 9.1 3.4 2.6 8.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Serglycin PF04360.12 GAM24689.1 - 0.33 10.9 8.3 0.23 11.4 5.6 1.9 2 0 0 2 2 2 0 Serglycin Kelch_4 PF13418.6 GAM24690.1 - 9.7e-13 47.9 3.3 0.0075 16.3 0.0 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM24690.1 - 1.7e-12 47.2 6.9 0.0051 17.1 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAM24690.1 - 3.6e-08 32.9 5.2 0.015 14.9 0.0 5.3 5 1 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 GAM24690.1 - 5.4e-08 32.9 0.6 0.17 12.2 0.0 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM24690.1 - 0.00029 20.8 2.2 0.25 11.4 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAM24690.1 - 0.0011 18.9 5.3 1.9 8.6 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 GAM24691.1 - 3.2e-08 33.6 3.4 0.013 15.7 0.2 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 GAM24691.1 - 1.7e-06 28.0 2.7 0.093 12.7 0.1 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Baculo_PEP_C PF04513.12 GAM24691.1 - 2.8e-06 27.4 2.2 4.3e-06 26.8 2.2 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_1 PF01344.25 GAM24691.1 - 1.2e-05 24.8 0.4 0.47 10.1 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAM24691.1 - 6.7e-05 22.7 0.9 0.32 11.0 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 GAM24691.1 - 0.00022 21.4 0.0 14 6.1 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain DUF1664 PF07889.12 GAM24691.1 - 0.15 12.1 0.9 0.27 11.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Kelch_5 PF13854.6 GAM24691.1 - 0.29 11.2 4.5 5.3 7.2 0.2 3.2 2 1 1 3 3 3 0 Kelch motif Kelch_6 PF13964.6 GAM24692.1 - 2.1e-12 46.9 6.5 0.00014 22.0 0.1 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAM24692.1 - 8.1e-09 35.4 3.2 0.0009 19.2 0.1 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM24692.1 - 3e-07 29.9 7.0 0.00058 19.4 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 GAM24692.1 - 1.8e-06 27.8 4.0 0.074 13.1 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 GAM24692.1 - 0.0001 22.5 1.3 1.3 9.4 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM24692.1 - 0.00056 19.8 6.7 0.12 12.4 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Baculo_PEP_C PF04513.12 GAM24692.1 - 0.0016 18.5 3.0 0.0032 17.5 3.0 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_6 PF13964.6 GAM24693.1 - 2.8e-14 52.8 5.9 5.8e-05 23.2 0.1 4.3 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAM24693.1 - 7.8e-12 44.6 1.9 3.3e-05 23.4 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM24693.1 - 6.2e-11 42.1 2.2 0.00038 20.4 0.1 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM24693.1 - 1.2e-08 35.1 0.3 0.047 14.0 0.0 4.7 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM24693.1 - 2.6e-05 24.0 0.7 0.28 11.2 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Baculo_PEP_C PF04513.12 GAM24693.1 - 4.4e-05 23.5 3.6 0.00012 22.1 3.6 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus zf-B_box PF00643.24 GAM24693.1 - 0.0025 17.9 6.2 0.0046 17.1 6.2 1.4 1 0 0 1 1 1 1 B-box zinc finger Kelch_5 PF13854.6 GAM24693.1 - 0.0028 17.6 1.7 0.66 10.0 0.1 2.7 3 0 0 3 3 3 2 Kelch motif Herpes_UL14 PF03580.14 GAM24693.1 - 0.53 10.5 5.5 12 6.1 5.5 2.5 1 1 0 1 1 1 0 Herpesvirus UL14-like protein DUF1664 PF07889.12 GAM24693.1 - 0.98 9.5 5.9 2 8.5 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) zf-B_box PF00643.24 GAM24694.1 - 1.1e-11 44.7 25.7 5.8e-06 26.4 9.5 2.4 2 0 0 2 2 2 2 B-box zinc finger Kelch_6 PF13964.6 GAM24694.1 - 6.5e-11 42.1 6.4 0.00022 21.4 0.0 5.0 4 1 1 5 5 4 2 Kelch motif Baculo_PEP_C PF04513.12 GAM24694.1 - 2.5e-09 37.3 15.3 9.5e-06 25.7 4.8 2.7 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_1 PF01344.25 GAM24694.1 - 1.1e-08 34.5 9.5 0.0053 16.3 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM24694.1 - 1.4e-08 34.6 9.8 0.0005 20.0 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM24694.1 - 7.2e-07 29.3 0.7 0.084 13.2 0.0 4.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM24694.1 - 1.7e-05 24.6 1.6 0.44 10.6 0.1 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 GAM24694.1 - 0.00045 20.1 8.6 0.18 11.8 0.2 4.4 5 0 0 5 5 4 1 Kelch motif HAUS-augmin3 PF14932.6 GAM24694.1 - 0.0027 17.3 13.7 0.063 12.8 3.3 2.5 2 1 0 2 2 2 2 HAUS augmin-like complex subunit 3 OmpH PF03938.14 GAM24694.1 - 0.01 16.2 5.4 0.32 11.3 1.0 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Apolipoprotein PF01442.18 GAM24694.1 - 0.016 15.1 3.8 0.13 12.2 0.9 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Rogdi_lz PF10259.9 GAM24694.1 - 0.016 14.7 4.9 0.25 10.8 0.5 2.3 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein GSH_synth_ATP PF03917.17 GAM24694.1 - 0.018 13.9 0.0 1.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic glutathione synthase, ATP binding domain PP-binding_2 PF14573.6 GAM24694.1 - 0.019 15.2 0.5 1.8 8.9 0.1 2.9 2 0 0 2 2 2 0 Acyl-carrier GAS PF13851.6 GAM24694.1 - 0.028 13.8 12.2 0.019 14.3 5.4 2.8 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding Peptidase_M75 PF09375.10 GAM24694.1 - 0.043 13.3 2.8 0.51 9.7 0.2 2.2 2 0 0 2 2 2 0 Imelysin IBR PF01485.21 GAM24694.1 - 0.047 13.9 10.8 1.6 9.0 3.6 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DUF2630 PF10944.8 GAM24694.1 - 0.055 13.9 8.4 1.2 9.6 0.3 4.1 4 0 0 4 4 3 0 Protein of unknown function (DUF2630) ApoLp-III PF07464.11 GAM24694.1 - 0.067 13.3 8.1 0.29 11.2 0.3 2.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) RPW8 PF05659.11 GAM24694.1 - 0.073 12.8 9.5 4.3 7.0 0.1 4.8 2 2 4 6 6 6 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 LRR_10 PF18805.1 GAM24694.1 - 0.088 12.5 0.1 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeat Exonuc_VII_L PF02601.15 GAM24694.1 - 0.13 11.8 9.4 0.31 10.6 3.4 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2130 PF09903.9 GAM24694.1 - 0.14 11.4 15.7 0.48 9.6 3.2 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Gp-FAR-1 PF05823.12 GAM24694.1 - 0.18 12.2 2.2 6.8 7.0 0.2 2.6 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) A_deaminase_N PF08451.11 GAM24694.1 - 0.23 11.8 2.6 5.8 7.3 0.2 2.5 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal DUF349 PF03993.12 GAM24694.1 - 0.26 11.6 4.5 7.4 6.9 0.9 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF2203 PF09969.9 GAM24694.1 - 0.41 11.4 8.8 1.4 9.6 0.8 3.3 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) CNDH2_C PF16858.5 GAM24694.1 - 0.64 9.8 14.9 0.53 10.1 4.1 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF1664 PF07889.12 GAM24694.1 - 0.94 9.5 21.2 1.1 9.3 2.8 4.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 GAM24694.1 - 1 10.3 9.2 9.1 7.3 0.8 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain FYVE PF01363.21 GAM24694.1 - 1.3 9.3 6.2 11 6.3 0.4 2.5 2 0 0 2 2 2 0 FYVE zinc finger zf-piccolo PF05715.13 GAM24694.1 - 1.6 8.9 8.9 14 5.9 2.2 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger DHR-2 PF06920.13 GAM24694.1 - 1.6 7.2 9.5 4.5 5.8 1.0 2.4 2 0 0 2 2 2 0 Dock homology region 2 zf-UBR PF02207.20 GAM24694.1 - 2.6 8.3 22.9 1.9 8.7 5.9 3.1 2 2 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) zf-RING_14 PF17978.1 GAM24694.1 - 2.8 8.4 9.0 5.7 7.4 1.7 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain NPV_P10 PF05531.12 GAM24694.1 - 2.8 8.5 17.4 31 5.1 0.0 4.7 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FYVE_2 PF02318.16 GAM24694.1 - 3.5 7.9 13.9 1.5 9.0 0.8 3.2 3 0 0 3 3 2 0 FYVE-type zinc finger DUF1640 PF07798.11 GAM24694.1 - 3.7 7.6 18.6 1.6 8.7 2.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Occludin_ELL PF07303.13 GAM24694.1 - 3.8 8.3 9.0 1.9 9.3 1.3 3.2 2 1 2 4 4 4 0 Occludin homology domain TMPIT PF07851.13 GAM24694.1 - 4 6.6 10.8 7.8 5.6 3.0 2.3 2 0 0 2 2 2 0 TMPIT-like protein LMBR1 PF04791.16 GAM24694.1 - 4.4 6.1 9.9 3.9 6.3 2.7 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein Spectrin PF00435.21 GAM24694.1 - 5.8 7.5 12.8 19 5.8 4.2 2.8 2 0 0 2 2 2 0 Spectrin repeat Snapin_Pallidin PF14712.6 GAM24694.1 - 6.1 7.3 9.1 19 5.7 0.4 3.0 2 1 0 2 2 2 0 Snapin/Pallidin PTPA PF03095.15 GAM24694.1 - 7.3 5.9 13.6 8.3 5.8 2.2 3.4 2 2 2 4 4 4 0 Phosphotyrosyl phosphate activator (PTPA) protein Kelch_4 PF13418.6 GAM24695.1 - 1.3e-09 37.9 2.9 0.0017 18.4 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM24695.1 - 9.6e-09 35.2 6.8 0.0054 17.0 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 GAM24695.1 - 1.1e-07 31.3 0.8 0.3 10.7 0.0 4.6 4 0 0 4 4 4 2 Kelch motif zf-B_box PF00643.24 GAM24695.1 - 1.4e-06 28.3 9.8 2.6e-06 27.5 9.8 1.4 1 0 0 1 1 1 1 B-box zinc finger Baculo_PEP_C PF04513.12 GAM24695.1 - 3.9e-05 23.7 0.7 7.4e-05 22.8 0.7 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_5 PF13854.6 GAM24695.1 - 0.00029 20.7 1.8 0.14 12.2 0.1 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 GAM24695.1 - 0.00049 20.3 0.3 1.8 8.9 0.0 4.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM24695.1 - 0.026 14.5 4.2 5.3 7.2 0.1 3.8 4 0 0 4 4 4 0 Kelch motif CdvA PF18822.1 GAM24695.1 - 0.061 13.2 0.3 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 CdvA-like coiled-coil domain RPW8 PF05659.11 GAM24695.1 - 0.079 12.6 1.8 2.5 7.8 0.0 3.2 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CAP_N PF01213.19 GAM24695.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PepSY_TM PF03929.16 GAM24696.1 - 0.097 12.3 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 PepSY-associated TM region GATA PF00320.27 GAM24697.1 - 2.6e-16 58.9 6.8 5.6e-16 57.9 6.8 1.6 1 0 0 1 1 1 1 GATA zinc finger BioY PF02632.14 GAM24698.1 - 5.3e-38 130.1 16.0 9.7e-38 129.3 16.0 1.4 1 0 0 1 1 1 1 BioY family ubiquitin PF00240.23 GAM24698.1 - 0.00043 20.0 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Neur_chan_memb PF02932.16 GAM24698.1 - 0.053 13.6 1.6 0.087 12.9 0.1 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3792 PF12670.7 GAM24698.1 - 0.72 10.0 19.0 0.15 12.3 12.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) Kelch_6 PF13964.6 GAM24699.1 - 1.1e-14 54.0 4.9 6.2e-05 23.1 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM24699.1 - 3.9e-11 42.8 3.6 0.0007 19.6 0.1 5.4 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM24699.1 - 6.3e-08 32.1 1.6 0.016 14.8 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 GAM24699.1 - 2e-07 31.1 0.4 0.63 10.4 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM24699.1 - 0.00025 20.9 0.8 1.5 8.9 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Baculo_PEP_C PF04513.12 GAM24699.1 - 0.0018 18.4 1.0 0.0033 17.5 1.0 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_2 PF07646.15 GAM24699.1 - 0.0082 16.1 0.9 2.5 8.2 0.0 3.1 3 0 0 3 3 3 1 Kelch motif GSH_synth_ATP PF03917.17 GAM24699.1 - 0.083 11.7 0.0 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain Csm2_III-A PF03750.13 GAM24699.1 - 0.16 12.8 1.1 0.36 11.7 1.1 1.5 1 0 0 1 1 1 0 Csm2 Type III-A DUF1664 PF07889.12 GAM24699.1 - 1.7 8.7 4.7 2.1 8.4 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Kelch_6 PF13964.6 GAM24700.1 - 1.5e-08 34.6 1.6 4.6e-05 23.6 0.1 3.9 2 1 1 3 3 3 2 Kelch motif Kelch_4 PF13418.6 GAM24700.1 - 1.6e-07 31.2 3.2 1.4e-06 28.2 0.3 3.2 2 1 1 3 3 3 1 Galactose oxidase, central domain zf-B_box PF00643.24 GAM24700.1 - 1.2e-05 25.4 9.8 2.6e-05 24.3 9.8 1.6 1 0 0 1 1 1 1 B-box zinc finger Kelch_1 PF01344.25 GAM24700.1 - 3.5e-05 23.3 7.3 0.0001 21.8 0.1 3.7 4 0 0 4 4 4 1 Kelch motif Baculo_PEP_C PF04513.12 GAM24700.1 - 0.00057 20.0 0.3 0.001 19.1 0.3 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_3 PF13415.6 GAM24700.1 - 0.00057 20.1 0.5 1.9 8.9 0.0 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain IpaB_EvcA PF03278.13 GAM24700.1 - 0.0026 17.5 0.4 0.0058 16.3 0.4 1.6 1 0 0 1 1 1 1 IpaB/EvcA family Kelch_2 PF07646.15 GAM24700.1 - 0.003 17.5 0.1 0.003 17.5 0.1 2.3 3 0 0 3 3 3 1 Kelch motif DUF1664 PF07889.12 GAM24700.1 - 0.012 15.7 3.7 0.53 10.3 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CAP_N PF01213.19 GAM24700.1 - 0.26 10.8 0.1 0.37 10.2 0.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Kelch_6 PF13964.6 GAM24701.1 - 1.5e-09 37.8 1.3 1.6e-05 25.0 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 GAM24701.1 - 8.1e-08 31.7 2.3 0.00058 19.4 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM24701.1 - 1.9e-07 30.9 3.2 7.4e-05 22.7 0.1 3.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM24701.1 - 0.00035 20.4 0.3 0.32 11.0 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 GAM24701.1 - 0.0014 18.9 0.2 0.28 11.5 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM24701.1 - 0.027 14.4 0.1 14 5.8 0.0 2.7 2 0 0 2 2 2 0 Kelch motif CorA PF01544.18 GAM24701.1 - 0.11 11.8 1.8 0.16 11.3 1.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PA14 PF07691.12 GAM24702.1 - 1.7e-13 50.6 0.4 2.9e-13 49.8 0.4 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 GAM24702.1 - 1e-09 38.1 47.1 1e-05 25.3 8.0 15.4 14 3 2 16 16 16 6 Dictyostelium (slime mold) repeat Profilin PF00235.19 GAM24705.1 - 0.017 15.4 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Profilin TAL_FSA PF00923.19 GAM24707.1 - 1.4e-91 306.9 0.1 1.6e-91 306.7 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Med21 PF11221.8 GAM24707.1 - 0.14 12.5 0.3 0.37 11.0 0.0 1.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex FNIP PF05725.12 GAM24708.1 - 2.2e-36 123.7 20.5 5.2e-12 45.7 0.0 5.5 3 1 3 6 6 6 6 FNIP Repeat COMM_domain PF07258.14 GAM24709.1 - 2.6e-17 62.7 0.1 5e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 COMM domain HHH_4 PF14490.6 GAM24709.1 - 0.018 15.0 0.0 6 6.9 0.0 2.6 1 1 1 2 2 2 0 Helix-hairpin-helix containing domain Ntox24 PF15529.6 GAM24709.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 24 WD40 PF00400.32 GAM24710.1 - 3.2e-48 160.7 23.7 8.8e-09 35.9 0.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM24710.1 - 1.2e-17 64.0 6.3 0.0018 18.6 0.1 7.2 2 1 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM24710.1 - 6.1e-06 25.4 0.3 0.16 10.9 0.0 3.8 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 GAM24710.1 - 0.012 14.7 6.0 0.31 10.0 0.1 3.6 3 1 0 4 4 4 0 Coatomer WD associated region WD40_like PF17005.5 GAM24710.1 - 0.013 14.8 0.2 0.22 10.8 0.1 2.6 1 1 0 2 2 2 0 WD40-like domain LisH_TPL PF17814.1 GAM24710.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 LisH-like dimerisation domain Kelch_1 PF01344.25 GAM24711.1 - 9.9e-11 41.1 2.5 0.0011 18.5 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM24711.1 - 2.9e-09 36.8 5.7 6.7e-06 26.0 0.0 5.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM24711.1 - 5.6e-08 32.8 7.3 0.24 11.8 0.0 5.0 6 0 0 6 6 6 3 Kelch motif zf-B_box PF00643.24 GAM24711.1 - 9.9e-08 32.0 6.1 2.1e-07 31.0 6.1 1.6 1 0 0 1 1 1 1 B-box zinc finger Kelch_2 PF07646.15 GAM24711.1 - 1.3e-06 28.2 1.1 0.37 10.9 0.0 3.7 2 1 1 3 3 3 3 Kelch motif Kelch_3 PF13415.6 GAM24711.1 - 4.5e-05 23.6 4.0 0.071 13.4 0.0 5.2 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM24711.1 - 6.8e-05 22.8 2.6 0.0087 16.0 0.0 3.3 3 0 0 3 3 3 1 Kelch motif RPW8 PF05659.11 GAM24711.1 - 0.046 13.4 1.2 0.57 9.9 0.8 2.4 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 AAA_5 PF07728.14 GAM24711.1 - 0.086 12.8 0.1 0.26 11.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DDE_Tnp_4 PF13359.6 GAM24712.1 - 2.3e-23 82.6 0.4 1.2e-21 77.1 0.3 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM24712.1 - 2.7e-08 33.7 1.9 4.7e-08 32.9 1.9 1.4 1 1 0 1 1 1 1 Transposase DDE domain Dicty_REP PF05086.12 GAM24713.1 - 4.9 5.0 6.4 7.6 4.4 6.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MFS_1 PF07690.16 GAM24715.1 - 6.3e-27 94.4 40.9 6.3e-27 94.4 40.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM24715.1 - 1.1e-08 34.4 26.3 7.3e-08 31.7 0.6 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter DBR1 PF05011.13 GAM24716.1 - 7.4e-19 68.5 0.8 1.1e-18 68.0 0.1 1.6 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 GAM24716.1 - 7.2e-08 33.2 0.3 1.1e-07 32.6 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2639 PF11121.8 GAM24716.1 - 0.0087 16.1 0.0 0.029 14.4 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2639) Metallophos_2 PF12850.7 GAM24716.1 - 0.012 15.8 0.0 0.051 13.8 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Kelch_4 PF13418.6 GAM24717.1 - 3.2e-13 49.5 3.5 4.8e-07 29.7 0.2 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM24717.1 - 1.6e-11 44.0 10.8 0.00021 21.4 0.1 5.0 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 GAM24717.1 - 1.6e-11 43.6 8.8 3.6e-05 23.3 0.1 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 GAM24717.1 - 2.3e-08 33.7 4.8 0.0045 16.9 0.1 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAM24717.1 - 6.2e-07 29.6 2.9 0.073 13.4 0.0 4.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM24717.1 - 0.0086 16.1 3.5 0.59 10.2 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 GAM24718.1 - 1.7e-11 44.0 3.1 0.0099 16.1 0.1 4.6 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAM24718.1 - 4.4e-09 36.2 11.8 5.6e-05 23.1 0.3 5.0 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM24718.1 - 3.3e-08 33.0 4.3 0.021 14.4 0.1 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 GAM24718.1 - 3.2e-06 26.9 1.2 0.51 10.4 0.0 4.3 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 GAM24718.1 - 2.8e-05 24.3 2.1 1.9 8.8 0.1 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM24718.1 - 0.061 13.3 3.4 5.4 7.1 0.1 3.6 3 0 0 3 3 3 0 Kelch motif CENP-B_dimeris PF09026.10 GAM24718.1 - 0.14 12.5 5.3 0.45 10.9 5.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 GAM24718.1 - 0.2 11.2 3.5 0.35 10.4 3.5 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting TFIIE-A_C PF11521.8 GAM24718.1 - 3.7 7.9 7.1 0.19 12.1 1.4 1.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha FAM176 PF14851.6 GAM24718.1 - 9.6 5.9 9.5 0.63 9.7 2.3 2.1 2 0 0 2 2 2 0 FAM176 family Kelch_6 PF13964.6 GAM24719.1 - 1.1e-11 44.5 7.1 7.4e-05 22.9 0.0 4.2 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAM24719.1 - 1.7e-10 40.7 5.3 0.00033 20.6 0.2 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM24719.1 - 2.3e-08 34.1 1.2 0.15 12.4 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM24719.1 - 5.9e-08 32.2 2.7 0.0094 15.5 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAM24719.1 - 8.1e-07 28.8 0.9 1 9.5 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 GAM24719.1 - 2.4e-06 27.4 4.1 0.17 11.9 0.1 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 GAM24720.1 - 4.8e-11 42.5 4.2 0.0042 17.3 0.2 4.3 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM24720.1 - 2.3e-10 40.3 9.0 0.00025 21.0 0.3 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM24720.1 - 9.1e-09 34.8 6.3 0.073 12.7 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 GAM24720.1 - 9e-07 28.6 1.6 0.23 11.5 0.1 4.0 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 GAM24720.1 - 3.7e-06 27.1 1.7 3.4 8.0 0.0 5.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM24720.1 - 7e-06 25.9 1.7 0.13 12.3 0.1 3.6 3 0 0 3 3 3 3 Kelch motif zf-B_box PF00643.24 GAM24720.1 - 1.1e-05 25.4 11.4 2e-05 24.6 11.4 1.4 1 0 0 1 1 1 1 B-box zinc finger DUF1796 PF08795.10 GAM24720.1 - 0.4 10.6 4.4 0.81 9.6 4.4 1.5 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) DUF5449 PF17528.2 GAM24721.1 - 0.054 13.3 0.1 0.058 13.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5449) AlphaC_C PF17480.2 GAM24721.1 - 0.07 13.2 0.8 0.09 12.8 0.8 1.2 1 0 0 1 1 1 0 AlphaC C-terminal Kelch_6 PF13964.6 GAM24722.1 - 7.4e-12 45.1 3.0 0.024 14.9 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAM24722.1 - 1.2e-09 37.5 4.1 0.00019 20.9 0.0 4.4 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM24722.1 - 2.1e-08 34.0 0.5 2.8e-05 24.0 0.1 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM24722.1 - 1e-06 28.9 0.7 0.06 13.7 0.0 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM24722.1 - 1e-06 28.5 2.0 0.93 9.6 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 GAM24722.1 - 0.0017 18.3 2.0 0.11 12.6 0.0 3.2 3 0 0 3 3 3 1 Kelch motif MAP65_ASE1 PF03999.12 GAM24723.1 - 8.7e-62 209.7 34.6 1.5e-61 208.9 34.6 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Cortex-I_coil PF09304.10 GAM24723.1 - 0.011 16.0 3.2 0.011 16.0 3.2 4.1 4 2 1 5 5 5 0 Cortexillin I, coiled coil Dpoe2NT PF12213.8 GAM24723.1 - 0.027 14.7 1.1 0.15 12.4 0.5 2.7 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal Orthopox_A5L PF06193.11 GAM24723.1 - 6.2 6.2 10.1 3.2 7.1 0.2 3.5 3 0 0 3 3 3 0 Orthopoxvirus A5L protein-like DUF19 PF01579.18 GAM24723.1 - 7.3 6.4 8.9 0.41 10.4 0.2 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF19) UPF0240 PF06784.11 GAM24725.1 - 1.2e-07 32.0 5.3 1.3e-07 31.9 2.9 2.3 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0240) MRP-L20 PF12824.7 GAM24725.1 - 0.0017 18.5 2.4 0.0028 17.8 0.7 2.2 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit L20 CUE PF02845.16 GAM24726.1 - 0.0025 17.5 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 CUE domain Baculo_PEP_C PF04513.12 GAM24726.1 - 0.017 15.1 3.0 0.017 15.1 3.0 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus UBA_4 PF14555.6 GAM24726.1 - 0.033 14.0 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain YtxH PF12732.7 GAM24726.1 - 0.32 11.6 4.9 0.78 10.3 0.1 3.0 2 1 0 3 3 3 0 YtxH-like protein Atg14 PF10186.9 GAM24726.1 - 0.36 9.9 19.1 0.0099 15.0 12.7 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF29 PF01724.16 GAM24726.1 - 0.41 10.9 10.4 7.2 6.8 10.3 2.5 1 1 0 1 1 1 0 Domain of unknown function DUF29 AI-2E_transport PF01594.16 GAM24726.1 - 0.42 9.7 0.7 0.68 9.0 0.7 1.3 1 0 0 1 1 1 0 AI-2E family transporter ArAE_2_N PF10337.9 GAM24726.1 - 2.4 7.1 4.7 0.61 9.0 1.6 1.6 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal DUF3347 PF11827.8 GAM24726.1 - 8.2 6.6 9.8 3.8 7.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) 4HBT PF03061.22 GAM24727.1 - 0.00029 21.1 0.2 0.0014 19.0 0.1 1.9 1 1 1 2 2 2 1 Thioesterase superfamily DUF2807 PF10988.8 GAM24727.1 - 0.0083 15.9 1.9 0.016 15.0 1.9 1.5 1 1 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain MCM PF00493.23 GAM24728.1 - 2.7e-89 298.1 0.0 5.3e-89 297.1 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 GAM24728.1 - 2.6e-28 98.2 1.1 5.3e-28 97.3 1.1 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 GAM24728.1 - 8.1e-26 90.3 0.7 1.5e-25 89.5 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 GAM24728.1 - 1.3e-10 41.1 0.1 1.1e-06 28.2 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAM24728.1 - 2.5e-08 34.0 0.0 9.1e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAM24728.1 - 2.9e-05 23.9 0.0 0.0002 21.2 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM24728.1 - 0.00014 22.3 0.0 0.0042 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF2624 PF11116.8 GAM24728.1 - 0.0031 18.4 0.8 0.31 11.9 0.0 2.9 2 1 0 3 3 2 1 Protein of unknown function (DUF2624) NTPase_1 PF03266.15 GAM24728.1 - 0.035 14.0 2.1 1.1 9.2 0.3 3.2 3 0 0 3 3 3 0 NTPase AAA_29 PF13555.6 GAM24728.1 - 0.052 13.3 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain TniB PF05621.11 GAM24728.1 - 0.061 12.7 0.1 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 GAM24728.1 - 0.088 13.2 0.1 0.74 10.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAM24728.1 - 0.1 13.0 1.3 54 4.2 0.1 3.5 3 0 0 3 3 3 0 RNA helicase Sigma54_activat PF00158.26 GAM24728.1 - 0.11 12.2 0.0 0.61 9.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 GAM24728.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DED PF01335.21 GAM24728.1 - 0.32 11.3 2.9 0.62 10.4 0.0 2.8 3 0 0 3 3 3 0 Death effector domain ADH_zinc_N PF00107.26 GAM24729.1 - 8e-18 64.7 0.0 1.4e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM24729.1 - 4.3e-10 39.4 0.0 8.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM24729.1 - 2e-06 28.9 0.0 4.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.25 GAM24729.1 - 0.022 14.2 0.3 0.035 13.5 0.3 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme MS_channel PF00924.18 GAM24729.1 - 0.037 13.6 1.0 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel ADH_N_2 PF16884.5 GAM24729.1 - 0.092 12.7 0.1 0.36 10.7 0.1 2.0 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Pkinase_Tyr PF07714.17 GAM24730.1 - 1.1e-94 316.6 0.0 2.4e-56 190.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAM24730.1 - 1.1e-80 270.8 4.7 2.1e-51 174.8 0.0 2.8 3 1 0 3 3 3 2 Protein kinase domain FHA_2 PF17913.1 GAM24730.1 - 6.4e-05 23.1 0.2 0.0043 17.2 0.0 3.4 3 0 0 3 3 3 1 FHA domain PIP49_C PF12260.8 GAM24730.1 - 0.081 12.6 0.2 6.2 6.4 0.0 2.7 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Peptidase_S24 PF00717.23 GAM24731.1 - 7.2e-10 38.7 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 GAM24731.1 - 4.1e-06 26.6 0.0 1.3e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 CrgA PF06781.12 GAM24731.1 - 0.0081 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Cell division protein CrgA Peroxin-13_N PF04088.13 GAM24731.1 - 0.036 14.3 0.1 0.048 13.9 0.1 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Orf78 PF06024.12 GAM24731.1 - 0.11 12.7 0.1 0.17 12.2 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Peptidase_C78 PF07910.13 GAM24732.1 - 2.1e-50 171.1 0.2 4.6e-50 170.0 0.2 1.6 1 0 0 1 1 1 1 Peptidase family C78 PhyH PF05721.13 GAM24732.1 - 1.1e-07 32.4 0.0 1.9e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Peptidase_C54 PF03416.19 GAM24732.1 - 0.016 14.6 5.1 0.18 11.2 1.2 3.5 3 1 1 4 4 4 0 Peptidase family C54 PAPS_reduct PF01507.19 GAM24733.1 - 6.7e-19 68.6 0.2 5.5e-13 49.3 0.2 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family ABC2_membrane PF01061.24 GAM24734.1 - 2e-32 112.3 15.1 3.5e-32 111.5 15.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAM24734.1 - 7.7e-27 94.5 0.1 1.6e-26 93.5 0.0 1.6 2 0 0 2 2 1 1 ABC transporter T2SSE PF00437.20 GAM24734.1 - 2.4e-06 26.8 0.1 5e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 GAM24734.1 - 0.00061 19.7 0.1 0.0015 18.4 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 GAM24734.1 - 0.0091 15.7 0.3 0.022 14.5 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 GAM24734.1 - 0.012 15.6 0.1 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.6 GAM24734.1 - 0.014 15.8 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 GAM24734.1 - 0.016 15.0 0.1 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 GAM24734.1 - 0.026 14.3 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAM24734.1 - 0.031 14.6 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 GAM24734.1 - 0.034 14.7 2.3 0.54 10.7 0.3 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAM24734.1 - 0.048 13.6 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 GAM24734.1 - 0.088 12.9 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 GAM24734.1 - 0.12 12.6 0.7 0.19 11.9 0.1 1.6 2 0 0 2 2 1 0 AAA domain Septin PF00735.18 GAM24734.1 - 0.13 11.6 1.2 8.8 5.5 0.1 2.1 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 GAM24734.1 - 0.13 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAM24734.1 - 0.2 11.4 0.1 0.37 10.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain SIR2 PF02146.17 GAM24735.1 - 9.2e-57 191.8 0.0 2.4e-56 190.5 0.0 1.7 1 0 0 1 1 1 1 Sir2 family zf-C3HC4_3 PF13920.6 GAM24735.1 - 0.019 14.8 2.9 0.019 14.8 2.9 2.8 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-UBP PF02148.19 GAM24735.1 - 0.037 14.3 0.6 0.037 14.3 0.6 3.1 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein TPP_enzyme_M PF00205.22 GAM24735.1 - 0.081 12.7 0.1 0.52 10.0 0.0 2.3 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF3973 PF13119.6 GAM24735.1 - 0.22 11.6 1.3 0.52 10.5 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) EF-1_beta_acid PF10587.9 GAM24735.1 - 0.57 10.7 2.1 1.2 9.7 2.1 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region zinc_ribbon_9 PF14369.6 GAM24735.1 - 3.8 7.8 10.7 0.81 10.0 1.0 3.6 4 0 0 4 4 4 0 zinc-ribbon P_C PF06640.11 GAM24736.1 - 0.24 11.5 2.2 0.31 11.2 2.2 1.1 1 0 0 1 1 1 0 P protein C-terminus Histone PF00125.24 GAM24737.1 - 2.1e-05 24.9 0.8 0.12 12.7 0.2 2.3 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAM24737.1 - 0.12 12.7 0.1 2.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Spore_permease PF03845.13 GAM24738.1 - 0.076 11.8 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Spore germination protein EGF_2 PF07974.13 GAM24738.1 - 0.19 12.1 16.9 0.49 10.8 16.9 1.7 1 0 0 1 1 1 0 EGF-like domain Cytomega_UL20A PF05984.12 GAM24738.1 - 0.28 11.5 1.7 0.5 10.7 0.1 2.3 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein I-EGF_1 PF18372.1 GAM24738.1 - 6.1 7.0 14.7 0.56 10.3 9.3 2.1 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 RVT_1 PF00078.27 GAM24739.1 - 9.6e-12 44.9 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 GAM24739.1 - 3.7e-05 23.4 1.6 9.7e-05 22.0 1.6 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Forkhead PF00250.18 GAM24739.1 - 0.02 15.2 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 Forkhead domain CAP PF00188.26 GAM24741.1 - 3.1e-15 57.1 0.7 4.1e-15 56.7 0.1 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family RIFIN PF02009.16 GAM24741.1 - 0.0023 17.9 1.0 0.0026 17.7 1.0 1.2 1 0 0 1 1 1 1 Rifin NPR3 PF03666.13 GAM24741.1 - 0.0082 15.0 1.0 0.011 14.5 1.0 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 SOG2 PF10428.9 GAM24741.1 - 0.041 13.1 18.5 0.051 12.8 18.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MCM_bind PF09739.9 GAM24741.1 - 0.58 8.5 4.1 0.8 8.1 4.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Apt1 PF10351.9 GAM24741.1 - 1.2 7.9 7.3 1.8 7.3 7.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hamartin PF04388.12 GAM24741.1 - 2 7.0 16.5 2.1 6.9 16.5 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 GAM24741.1 - 4.5 5.7 7.6 4.7 5.7 7.6 1.2 1 0 0 1 1 1 0 Macoilin family DUF1180 PF06679.12 GAM24741.1 - 8.1 6.8 12.0 6.3 7.2 10.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) AAA_11 PF13086.6 GAM24742.1 - 6.2e-18 65.5 0.0 2.4e-08 34.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 GAM24742.1 - 1.1e-15 57.8 0.1 3e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM24742.1 - 4.1e-12 46.2 0.0 8.1e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM24742.1 - 1.3e-09 38.6 0.2 3.9e-09 37.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GAM24742.1 - 8.2e-06 25.7 0.2 0.097 12.4 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 GAM24742.1 - 2.7e-05 24.0 0.1 6.9e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 GAM24742.1 - 0.0004 20.1 0.0 0.00088 19.1 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 GAM24742.1 - 0.0026 17.7 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Helicase_RecD PF05127.14 GAM24742.1 - 0.0089 15.9 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 GAM24742.1 - 0.062 13.6 0.1 0.45 10.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 GAM24742.1 - 0.063 12.7 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 GAM24742.1 - 0.069 13.5 0.0 0.32 11.4 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain SCAPER_N PF16501.5 GAM24742.1 - 0.14 12.1 0.0 9.8 6.3 0.0 3.0 3 0 0 3 3 3 0 S phase cyclin A-associated protein in the endoplasmic reticulum FKS1_dom1 PF14288.6 GAM24742.1 - 0.37 11.1 6.5 0.73 10.2 0.1 3.4 3 0 0 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Rap_GAP PF02145.15 GAM24743.1 - 1e-48 165.3 0.6 2.8e-48 163.9 0.1 2.1 2 0 0 2 2 2 1 Rap/ran-GAP Cellulase PF00150.18 GAM24744.1 - 1.2e-35 123.3 6.1 1.7e-35 122.8 6.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM49 PF09478.10 GAM24744.1 - 7.7e-10 39.0 2.1 7.7e-10 39.0 2.1 3.0 3 1 0 3 3 3 1 Carbohydrate binding domain CBM49 Mucin-like PF16058.5 GAM24744.1 - 8.5e-06 25.8 76.8 6.4e-05 23.0 39.7 2.4 1 1 1 2 2 2 2 Mucin-like Utp14 PF04615.13 GAM24744.1 - 4 5.9 5.8 5.3 5.5 5.8 1.2 1 0 0 1 1 1 0 Utp14 protein TFIIA PF03153.13 GAM24744.1 - 7.2 6.5 9.3 10 6.0 9.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NIF PF03031.18 GAM24745.1 - 6.7e-54 181.9 0.4 9.6e-54 181.4 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PP2C PF00481.21 GAM24746.1 - 3e-60 204.0 0.0 5.5e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAM24746.1 - 0.061 13.0 0.3 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein phosphatase 2C Glyco_hydr_30_2 PF14587.6 GAM24747.1 - 6.8e-13 48.9 7.4 6.8e-13 48.9 7.4 1.7 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 GAM24747.1 - 0.00054 20.1 1.0 0.00054 20.1 1.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Amino_oxidase PF01593.24 GAM24748.1 - 3.2e-61 208.0 0.0 9.4e-61 206.5 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM24748.1 - 4.8e-15 55.5 0.1 9.3e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM24748.1 - 7.2e-09 35.7 0.0 9.1e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAM24748.1 - 1.9e-06 27.2 0.9 0.034 13.2 0.1 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAM24748.1 - 3.6e-06 26.3 0.0 5.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAM24748.1 - 3.3e-05 22.8 0.1 0.0077 15.0 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 GAM24748.1 - 0.00014 21.3 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM24748.1 - 0.00038 19.8 0.0 0.00068 18.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 GAM24748.1 - 0.00054 19.3 0.1 0.0087 15.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM24748.1 - 0.0019 17.5 1.7 0.14 11.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM24748.1 - 0.0034 17.9 1.2 0.025 15.1 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM24748.1 - 0.012 14.8 1.2 1.5 7.8 0.1 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAM24748.1 - 0.028 13.6 0.3 0.097 11.9 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain DUF2204 PF09970.9 GAM24748.1 - 0.055 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Snapin_Pallidin PF14712.6 GAM24750.1 - 5.8e-22 77.9 0.4 5.8e-22 77.9 0.4 1.9 2 0 0 2 2 2 1 Snapin/Pallidin DUF489 PF04356.12 GAM24750.1 - 0.0038 17.3 0.4 0.0064 16.5 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF489) GCN5L1 PF06320.13 GAM24750.1 - 0.014 15.5 0.0 0.014 15.5 0.0 2.4 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) FapA PF03961.13 GAM24750.1 - 0.04 12.5 0.2 0.04 12.5 0.2 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A TssO PF17561.2 GAM24750.1 - 0.08 13.0 0.3 0.08 13.0 0.3 2.9 3 0 0 3 3 3 0 Type VI secretion system, TssO NifU_N PF01592.16 GAM24751.1 - 2.1e-52 176.7 0.1 2.8e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Acetyltransf_1 PF00583.25 GAM24753.1 - 1.9e-07 31.3 0.0 2.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM24753.1 - 2.7e-05 24.5 0.0 4.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM24753.1 - 0.00059 19.8 0.0 0.00091 19.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM24753.1 - 0.00061 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 GAM24753.1 - 0.0093 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 GAM24753.1 - 0.18 11.9 0.0 0.58 10.2 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ACOX PF01756.19 GAM24754.1 - 2.3e-06 27.3 0.4 2.9e-06 26.9 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA oxidase MAAL_N PF05034.13 GAM24754.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus BRCT PF00533.26 GAM24755.1 - 3.6e-10 40.1 0.8 7.7e-10 39.0 0.8 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM24755.1 - 1.9e-06 28.2 0.1 1.9e-06 28.2 0.1 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 GAM24755.1 - 0.00042 20.2 1.0 0.00091 19.1 0.1 2.0 2 0 0 2 2 2 1 twin BRCT domain DUF3246 PF11596.8 GAM24755.1 - 0.0045 16.5 8.1 0.009 15.5 7.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3246) CUE PF02845.16 GAM24755.1 - 0.012 15.2 0.0 1.7 8.4 0.1 2.5 2 0 0 2 2 2 0 CUE domain LIG3_BRCT PF16759.5 GAM24755.1 - 0.036 14.3 0.1 0.19 12.1 0.1 2.3 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain NPH-II PF12011.8 GAM24755.1 - 0.4 10.5 2.4 8.3 6.3 0.0 3.0 3 0 0 3 3 3 0 RNA helicase NPH-II TERB2 PF15101.6 GAM24755.1 - 5.7 6.9 12.0 9.5 6.2 10.8 1.9 1 1 1 2 2 2 0 Telomere-associated protein TERB2 Rap_GAP PF02145.15 GAM24756.1 - 4.9e-58 195.8 0.7 9.2e-58 194.8 0.7 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Peptidase_S49_N PF08496.10 GAM24756.1 - 0.012 15.7 3.4 0.037 14.1 3.4 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rib_recp_KP_reg PF05104.12 GAM24756.1 - 5.4 8.0 27.4 17 6.4 14.2 3.6 3 0 0 3 3 3 0 Ribosome receptor lysine/proline rich region DUF4710 PF15828.5 GAM24757.1 - 0.14 12.3 0.8 0.86 9.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) FNIP PF05725.12 GAM24759.1 - 9.4e-37 124.9 14.7 2.4e-11 43.6 0.0 6.4 4 2 1 5 5 5 5 FNIP Repeat AftA_C PF12249.8 GAM24760.1 - 0.0072 16.0 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 Arabinofuranosyltransferase A C terminal AAA_22 PF13401.6 GAM24760.1 - 0.026 14.8 0.0 0.052 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAM24760.1 - 0.097 13.0 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CDC45 PF02724.14 GAM24760.1 - 0.25 9.6 2.3 0.33 9.2 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_1b PF00579.25 GAM24761.1 - 1.4e-61 208.4 0.0 1.7e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RCC1 PF00415.18 GAM24762.1 - 1e-79 262.9 18.0 2.4e-15 56.9 0.2 8.9 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM24762.1 - 2e-38 129.4 28.5 6.6e-07 29.0 0.5 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Retro_M PF02813.14 GAM24762.1 - 0.0058 17.0 0.3 2.7 8.5 0.0 3.8 5 0 0 5 5 5 1 Retroviral M domain RhoGEF PF00621.20 GAM24763.1 - 6.6e-40 137.3 2.8 6.6e-40 137.3 2.8 1.7 2 0 0 2 2 2 1 RhoGEF domain FAM199X PF15814.5 GAM24763.1 - 0.044 12.9 8.4 0.091 11.8 8.4 1.5 1 0 0 1 1 1 0 Protein family FAM199X FNIP PF05725.12 GAM24764.1 - 6.6e-72 237.5 6.7 1.2e-12 47.7 0.1 10.4 6 3 3 10 10 10 9 FNIP Repeat Adeno_PX PF05829.12 GAM24764.1 - 0.18 11.7 0.1 3.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Adenovirus late L2 mu core protein (Protein X) Utp21 PF04192.12 GAM24765.1 - 7.4e-56 189.3 6.2 7.4e-56 189.3 6.2 2.0 1 1 1 2 2 2 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 GAM24765.1 - 1.7e-15 57.1 2.1 7.4e-05 23.0 0.0 5.8 3 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM24765.1 - 4e-15 55.9 19.9 5.9e-05 23.8 0.1 9.8 10 0 0 10 10 10 4 WD domain, G-beta repeat WD40_like PF17005.5 GAM24765.1 - 2.4e-06 27.1 4.6 0.00019 20.8 0.1 3.0 3 0 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 GAM24765.1 - 0.00071 19.5 1.1 0.37 10.6 0.0 3.7 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Herpes_TAF50 PF03326.13 GAM24765.1 - 0.054 12.2 1.6 0.085 11.5 1.6 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Ge1_WD40 PF16529.5 GAM24765.1 - 0.62 9.0 7.4 12 4.7 0.0 5.0 5 2 1 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PSI PF01437.25 GAM24766.1 - 1.8e-05 25.2 10.7 3e-05 24.5 10.7 1.4 1 0 0 1 1 1 1 Plexin repeat Orf78 PF06024.12 GAM24766.1 - 0.03 14.6 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) PLDc_2 PF13091.6 GAM24768.1 - 5e-14 52.3 0.0 3.9e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAM24768.1 - 1.3e-05 25.1 0.5 0.24 11.6 0.4 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif GST_C_3 PF14497.6 GAM24769.1 - 1e-21 77.0 0.1 1.5e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM24769.1 - 2.3e-10 40.5 0.1 7.4e-10 38.9 0.0 1.7 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM24769.1 - 3.8e-07 30.3 0.0 7.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM24769.1 - 4.2e-06 26.7 0.1 1.5e-05 24.9 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 GAM24769.1 - 0.012 15.4 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAM24769.1 - 0.067 13.8 0.0 2.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM24769.1 - 0.076 13.4 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ins134_P3_kin PF05770.11 GAM24770.1 - 7.5e-46 156.2 0.5 1.1e-45 155.7 0.5 1.2 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 GAM24770.1 - 6.1e-07 29.7 0.0 1.5e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Pkinase PF00069.25 GAM24771.1 - 1.4e-58 198.3 0.0 2.5e-58 197.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24771.1 - 1.2e-35 123.0 0.0 2.3e-35 122.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM24771.1 - 1.1e-12 47.9 0.2 2.1e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Spore_coat_CotO PF14153.6 GAM24771.1 - 0.009 16.0 7.2 0.016 15.1 7.2 1.3 1 0 0 1 1 1 1 Spore coat protein CotO APH PF01636.23 GAM24771.1 - 0.014 15.3 0.1 0.69 9.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAM24771.1 - 0.095 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 GAM24771.1 - 0.29 9.9 0.0 0.29 9.9 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase DUF5385 PF17359.2 GAM24771.1 - 1.1 8.7 5.1 0.35 10.4 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Sporozoite_P67 PF05642.11 GAM24771.1 - 1.3 7.1 9.7 1.7 6.6 9.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spt20 PF12090.8 GAM24771.1 - 7.6 6.1 21.2 22 4.6 21.2 1.8 1 1 0 1 1 1 0 Spt20 family ABC_tran PF00005.27 GAM24772.1 - 1.5e-27 96.8 0.0 2.5e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM24772.1 - 2.9e-06 27.3 1.9 0.0011 18.9 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAM24772.1 - 0.0009 19.2 0.1 0.0022 17.9 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 GAM24772.1 - 0.0013 19.2 0.1 0.0019 18.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 GAM24772.1 - 0.0021 17.8 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain SbcCD_C PF13558.6 GAM24772.1 - 0.0094 16.2 0.2 0.24 11.7 0.2 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 GAM24772.1 - 0.06 13.3 0.6 3.5 7.5 0.1 2.3 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 GAM24772.1 - 0.093 12.5 0.0 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Cullin PF00888.22 GAM24774.1 - 1.2e-11 43.9 0.4 1.5e-11 43.7 0.4 1.0 1 0 0 1 1 1 1 Cullin family EF-hand_2 PF09068.11 GAM24774.1 - 0.076 13.2 1.2 0.13 12.4 1.2 1.3 1 0 0 1 1 1 0 EF hand RHH_8 PF17723.1 GAM24775.1 - 0.0066 16.6 0.7 0.41 10.8 0.0 2.8 2 0 0 2 2 2 2 Ribbon-Helix-Helix transcriptional regulator family Fibrillarin PF01269.17 GAM24776.1 - 1.9e-99 331.4 0.0 2.2e-99 331.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 GAM24776.1 - 0.00053 19.7 0.0 0.00083 19.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 GAM24776.1 - 0.16 12.0 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Na_Ca_ex PF01699.24 GAM24777.1 - 8.1e-15 55.1 30.3 1.2e-07 31.8 18.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MWFE PF15879.5 GAM24777.1 - 0.042 14.0 0.2 0.64 10.2 0.0 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit COX7a PF02238.15 GAM24777.1 - 0.046 14.1 0.1 0.046 14.1 0.1 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII DUF2157 PF09925.9 GAM24777.1 - 2.3 8.0 9.0 4 7.2 5.3 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) SH3_2 PF07653.17 GAM24778.1 - 1.1e-13 50.6 0.1 1.7e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAM24778.1 - 8.1e-12 44.8 0.3 1.2e-11 44.2 0.3 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM24778.1 - 3.3e-09 36.2 0.2 4.9e-09 35.7 0.2 1.3 1 0 0 1 1 1 1 SH3 domain DZR PF12773.7 GAM24778.1 - 0.0045 17.0 1.4 0.0086 16.1 1.4 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_3 PF13920.6 GAM24778.1 - 0.07 13.0 1.3 0.1 12.5 1.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 GAM24778.1 - 0.36 10.6 4.7 0.64 9.8 4.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF4551 PF15087.6 GAM24778.1 - 2.6 6.8 6.3 3.5 6.4 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CCDC92 PF14916.6 GAM24780.1 - 0.0017 18.1 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Tetraspanin PF00335.20 GAM24781.1 - 6e-27 94.8 13.9 7.6e-27 94.5 13.9 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF3810 PF12725.7 GAM24781.1 - 0.00038 19.9 0.4 0.0007 19.0 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3810) DUF2809 PF10990.8 GAM24781.1 - 0.0055 17.3 2.2 0.0055 17.3 2.2 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2809) EcsB PF05975.12 GAM24781.1 - 0.56 9.0 7.0 5.3 5.8 0.0 2.5 2 1 1 3 3 3 0 Bacterial ABC transporter protein EcsB DUF4131 PF13567.6 GAM24781.1 - 3.3 7.3 10.3 9 5.9 7.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3042 PF11240.8 GAM24781.1 - 7.1 6.7 5.6 31 4.7 1.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) Abhydrolase_1 PF00561.20 GAM24782.1 - 8.6e-23 81.3 0.2 8.2e-22 78.1 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM24782.1 - 6.9e-15 56.2 0.0 9.4e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM24782.1 - 1.9e-11 43.7 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 GAM24782.1 - 0.0053 15.5 0.0 0.0065 15.2 0.0 1.5 1 1 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 GAM24782.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.12 GAM24782.1 - 0.037 14.0 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.11 GAM24782.1 - 0.037 13.3 0.0 0.49 9.7 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 GAM24782.1 - 0.052 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 GAM24782.1 - 0.062 12.2 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 GAM24782.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DNA_topoisoIV PF00521.20 GAM24783.1 - 1.7e-111 373.2 16.3 8.1e-86 288.6 0.0 2.7 1 1 1 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 GAM24783.1 - 3.7e-47 159.8 1.9 3.7e-47 159.8 1.9 4.4 5 0 0 5 5 5 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 GAM24783.1 - 2.7e-21 75.8 0.3 1.2e-20 73.7 0.3 2.1 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 GAM24783.1 - 4.5e-13 49.7 0.0 1.2e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GAM24783.1 - 5.7e-06 26.5 0.1 3.5e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Toprim domain Cornichon PF03311.14 GAM24784.1 - 1.1e-33 116.2 14.7 1.3e-33 115.9 14.7 1.0 1 0 0 1 1 1 1 Cornichon protein Arm PF00514.23 GAM24785.1 - 2.2e-05 24.3 0.0 5.7e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HMA PF00403.26 GAM24785.1 - 0.00085 19.7 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain FNIP PF05725.12 GAM24786.1 - 2.1e-58 194.2 11.7 3.9e-12 46.1 0.0 9.9 6 3 4 11 11 11 10 FNIP Repeat DUF1769 PF08588.10 GAM24786.1 - 0.00021 21.4 0.4 16 5.8 0.0 4.3 2 1 2 4 4 4 3 Protein of unknown function (DUF1769) Meth_synt_2 PF01717.18 GAM24787.1 - 1.6e-153 510.7 0.0 1.9e-147 490.7 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 GAM24787.1 - 2e-105 352.8 0.0 7.1e-99 331.3 0.0 4.0 3 1 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain vWA-TerF-like PF10138.9 GAM24788.1 - 1.9e-10 41.2 0.1 2.7e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 GAM24788.1 - 1.1e-06 29.0 0.1 1.5e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM24788.1 - 3.6e-05 24.4 0.0 5.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAM24788.1 - 6.1e-05 23.0 0.0 9.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain CTP_transf_1 PF01148.20 GAM24789.1 - 4e-65 220.2 29.1 8.1e-65 219.2 29.1 1.5 1 1 0 1 1 1 1 Cytidylyltransferase family PBP1_TM PF14812.6 GAM24789.1 - 0.068 13.5 1.7 0.095 13.1 0.3 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.7 GAM24790.1 - 4.5e-07 30.4 0.0 0.00014 22.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM24790.1 - 0.0002 21.5 0.2 9.5 7.2 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 GAM24790.1 - 0.00079 19.9 0.2 3.7 8.3 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM24790.1 - 0.047 14.0 0.2 71 3.9 0.0 3.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DEAD PF00270.29 GAM24791.1 - 1.3e-15 57.6 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase SPRY PF00622.28 GAM24791.1 - 2.7e-14 53.3 0.4 5.1e-14 52.4 0.4 1.5 1 0 0 1 1 1 1 SPRY domain Acetyltransf_3 PF13302.7 GAM24792.1 - 2.1e-13 51.1 0.0 2.9e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM24792.1 - 0.00014 22.0 0.1 0.00019 21.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM24792.1 - 0.0052 17.0 0.0 0.0082 16.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family NAGidase PF07555.13 GAM24793.1 - 5.3e-15 55.5 0.0 1.9e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 beta-N-acetylglucosaminidase zf-C2HC5 PF06221.13 GAM24793.1 - 5.8e-15 55.0 8.1 1.2e-14 54.0 8.1 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type UvrD-helicase PF00580.21 GAM24793.1 - 0.00014 21.5 2.7 0.00014 21.5 2.7 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SMC_N PF02463.19 GAM24797.1 - 2.2e-49 167.9 63.8 1.2e-48 165.5 63.8 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAM24797.1 - 5.5e-22 78.3 0.2 2.6e-21 76.1 0.2 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 GAM24797.1 - 2.8e-10 40.4 12.0 2.8e-10 40.4 12.0 4.3 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 GAM24797.1 - 1.1e-07 31.9 18.3 0.00087 19.2 0.6 3.6 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM24797.1 - 0.00027 20.6 0.1 0.00096 18.8 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM24797.1 - 0.0013 19.2 49.2 0.0013 19.2 49.2 7.1 1 1 3 4 4 4 1 AAA domain Clathrin PF00637.20 GAM24798.1 - 1.7e-22 79.8 3.1 1.7e-22 79.8 3.1 4.1 2 1 2 4 4 4 1 Region in Clathrin and VPS Vps39_2 PF10367.9 GAM24798.1 - 1.8e-07 31.6 2.5 5.5e-07 30.0 2.5 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 ANAPC4_WD40 PF12894.7 GAM24798.1 - 0.0011 19.2 0.0 0.06 13.6 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-rbx1 PF12678.7 GAM24798.1 - 0.0016 18.6 3.6 0.0057 16.9 3.6 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 GAM24798.1 - 0.0027 17.7 1.9 0.011 15.8 1.9 2.0 1 0 0 1 1 1 1 Zinc-finger WD40 PF00400.32 GAM24798.1 - 0.02 15.8 1.5 0.08 13.8 0.3 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Helicase_PWI PF18149.1 GAM24798.1 - 0.021 15.0 1.8 0.29 11.3 0.7 2.7 2 0 0 2 2 2 0 N-terminal helicase PWI domain zf-ANAPC11 PF12861.7 GAM24798.1 - 0.024 14.7 0.9 0.06 13.4 0.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 GAM24798.1 - 0.18 11.6 11.8 0.27 11.0 7.7 2.8 2 0 0 2 2 2 0 RING-like zinc finger Vps39_1 PF10366.9 GAM24798.1 - 0.3 11.4 7.2 0.37 11.1 0.2 3.3 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 C1_1 PF00130.22 GAM24798.1 - 0.8 9.6 4.2 3 7.8 4.2 2.0 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RXT2_N PF08595.11 GAM24798.1 - 1.2 9.2 13.1 0.34 10.9 8.6 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal zf-RING_UBOX PF13445.6 GAM24798.1 - 2.1 8.4 7.4 0.79 9.8 1.8 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 GAM24798.1 - 5 7.1 8.8 8.6 6.3 4.1 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FNIP PF05725.12 GAM24799.1 - 6.8e-117 381.5 37.5 2.2e-14 53.3 0.1 11.8 8 2 2 12 12 12 11 FNIP Repeat LRR_5 PF13306.6 GAM24799.1 - 7.9e-05 22.6 0.3 0.77 9.7 0.0 3.8 3 0 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) Radical_SAM PF04055.21 GAM24799.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily Pyr_redox_2 PF07992.14 GAM24800.1 - 5.8e-68 229.3 8.7 5.8e-68 229.3 8.7 1.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAM24800.1 - 1.2e-39 134.9 0.1 2.8e-39 133.8 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAM24800.1 - 1.9e-20 73.2 13.6 1.8e-19 70.1 1.3 3.9 4 1 1 5 5 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM24800.1 - 1.1e-11 44.6 8.7 1.1e-08 34.7 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM24800.1 - 1.2e-09 38.0 9.1 1.4e-09 37.8 0.6 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM24800.1 - 6.7e-06 25.1 10.9 0.00022 20.1 0.3 4.0 3 1 1 4 4 4 2 HI0933-like protein GIDA PF01134.22 GAM24800.1 - 7e-06 25.4 10.3 0.00023 20.4 5.3 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 GAM24800.1 - 9e-06 25.8 6.7 0.00048 20.3 1.9 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAM24800.1 - 6.4e-05 22.2 3.5 0.00066 18.9 0.1 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 GAM24800.1 - 7.1e-05 22.2 5.7 0.0068 15.7 0.3 3.2 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 GAM24800.1 - 0.0001 21.5 3.8 0.0001 21.5 3.8 3.0 3 1 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 GAM24800.1 - 0.0028 17.6 1.6 0.0066 16.4 0.6 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 GAM24800.1 - 0.003 16.8 0.1 0.003 16.8 0.1 2.7 3 1 0 3 3 3 1 Thi4 family Lycopene_cycl PF05834.12 GAM24800.1 - 0.003 16.7 0.9 0.039 13.0 0.0 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 GAM24800.1 - 0.018 14.3 0.4 0.4 9.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase XdhC_C PF13478.6 GAM24800.1 - 0.039 14.5 0.0 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_3 PF01494.19 GAM24800.1 - 0.11 11.7 14.7 0.3 10.3 2.6 3.4 3 1 0 3 3 3 0 FAD binding domain DAO PF01266.24 GAM24800.1 - 2.4 7.6 26.9 0.69 9.4 0.8 4.1 2 2 2 4 4 4 0 FAD dependent oxidoreductase DUF3430 PF11912.8 GAM24801.1 - 1.4e-08 35.1 14.5 2.4e-08 34.3 14.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 GAM24801.1 - 5.2 7.4 15.1 7.4 6.9 0.4 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF3586) PH PF00169.29 GAM24802.1 - 6.2e-22 78.1 2.7 1.2e-21 77.2 2.7 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM24802.1 - 2.6e-07 31.0 7.1 2.6e-06 27.8 7.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 GAM24802.1 - 2.5e-05 24.3 0.5 4.6e-05 23.5 0.5 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM24802.1 - 0.00078 19.7 1.1 0.002 18.4 1.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 GAM24802.1 - 0.00083 19.7 0.4 0.0025 18.2 0.4 1.7 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PH_9 PF15410.6 GAM24802.1 - 0.011 16.1 1.7 0.26 11.6 1.7 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 GAM24802.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PRP38 PF03371.15 GAM24804.1 - 2.6e-53 180.5 0.1 3.5e-53 180.1 0.1 1.2 1 0 0 1 1 1 1 PRP38 family DUF4611 PF15387.6 GAM24805.1 - 0.67 10.2 4.7 0.19 12.0 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) F-box PF00646.33 GAM24806.1 - 0.00036 20.3 0.2 0.0025 17.6 0.2 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAM24806.1 - 0.00069 19.5 0.8 0.0022 17.8 0.3 2.0 2 0 0 2 2 2 1 F-box-like Ank_4 PF13637.6 GAM24807.1 - 8.8e-31 105.9 10.8 2.7e-07 31.0 0.0 7.8 4 1 5 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM24807.1 - 1e-29 102.9 9.3 1.8e-08 34.8 0.0 5.3 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM24807.1 - 2.8e-24 84.9 11.2 0.00027 21.2 0.0 10.1 4 4 7 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM24807.1 - 3e-16 57.8 8.3 0.6 10.8 0.0 10.3 9 2 2 11 11 11 3 Ankyrin repeat Ank PF00023.30 GAM24807.1 - 1.6e-05 25.1 1.4 54 4.5 0.1 7.5 5 2 1 6 6 6 0 Ankyrin repeat DUF5049 PF16468.5 GAM24807.1 - 3.8e-05 23.5 4.8 21 5.1 0.1 7.7 6 2 4 10 10 10 1 Domain of unknown function (DUF5049) VHL_C PF17211.3 GAM24807.1 - 0.054 13.5 0.1 57 3.8 0.0 4.5 6 0 0 6 6 6 0 VHL box domain DUF4397 PF14344.6 GAM24808.1 - 1e-11 45.6 1.8 3.5e-07 31.0 0.2 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF4397) MPC PF03650.13 GAM24809.1 - 1.5e-20 73.3 0.4 1.7e-20 73.2 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MPC PF03650.13 GAM24810.1 - 8.9e-18 64.4 0.0 1.2e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers ANTH PF07651.16 GAM24811.1 - 1.6e-48 165.1 3.3 1.6e-48 165.1 3.3 2.0 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 GAM24811.1 - 0.00049 20.2 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 ENTH domain RRM_1 PF00076.22 GAM24812.1 - 2.3e-26 91.4 4.6 7.5e-10 38.5 0.3 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cofilin_ADF PF00241.20 GAM24813.1 - 2.4e-12 46.7 0.0 2.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EF-hand_6 PF13405.6 GAM24814.1 - 3.9e-16 57.5 1.3 2.9e-06 26.8 0.1 3.7 4 2 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 GAM24814.1 - 9.1e-15 54.9 0.0 6.2e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAM24814.1 - 1.7e-13 49.0 0.7 9.8e-06 24.8 0.0 4.1 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 GAM24814.1 - 4.6e-12 45.6 0.4 3.7e-06 26.7 0.0 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 GAM24814.1 - 1.3e-06 27.7 0.4 0.016 14.7 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 GAM24814.1 - 0.00018 21.7 0.0 0.27 11.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 GAM24814.1 - 0.012 15.6 0.0 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF853 PF05872.12 GAM24814.1 - 0.021 13.4 0.0 0.023 13.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) EFhand_Ca_insen PF08726.10 GAM24814.1 - 0.03 14.4 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF2666 PF10869.8 GAM24814.1 - 0.037 14.2 0.0 1.1 9.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DAP_epimerase PF01678.19 GAM24815.1 - 7.1e-24 84.3 4.1 4.3e-15 55.9 0.1 3.1 4 0 0 4 4 4 2 Diaminopimelate epimerase Zn_Tnp_IS1595 PF12760.7 GAM24816.1 - 0.052 13.5 18.8 0.59 10.2 4.8 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TBCC_N PF16752.5 GAM24816.1 - 0.19 12.1 8.8 0.5 10.8 8.8 1.7 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Zn-ribbon_8 PF09723.10 GAM24816.1 - 0.24 11.6 10.9 2.4 8.3 0.6 3.6 3 0 0 3 3 3 0 Zinc ribbon domain DUF1451 PF07295.11 GAM24816.1 - 0.94 9.5 5.2 10 6.1 1.6 2.6 2 0 0 2 2 2 0 Zinc-ribbon containing domain OrfB_Zn_ribbon PF07282.11 GAM24816.1 - 3.2 7.8 13.8 4 7.4 3.1 2.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF2678 PF10856.8 GAM24818.1 - 6.1e-11 42.3 0.4 9.1e-11 41.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) TauE PF01925.19 GAM24818.1 - 0.0045 16.7 2.3 0.0063 16.2 2.3 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Acyl_transf_3 PF01757.22 GAM24818.1 - 0.0055 15.8 2.4 0.0072 15.4 2.4 1.2 1 0 0 1 1 1 1 Acyltransferase family AA_permease_2 PF13520.6 GAM24818.1 - 0.009 14.9 1.9 0.012 14.5 1.9 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_3_6 PF07332.11 GAM24818.1 - 0.017 15.2 4.0 0.017 15.2 4.0 1.9 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4181 PF13789.6 GAM24818.1 - 0.028 14.7 0.7 0.046 14.0 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) XK-related PF09815.9 GAM24818.1 - 0.049 12.7 1.8 0.061 12.4 1.8 1.1 1 0 0 1 1 1 0 XK-related protein DUF3290 PF11694.8 GAM24818.1 - 0.093 12.7 2.6 0.35 10.8 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3290) DUF2254 PF10011.9 GAM24818.1 - 0.17 10.7 0.4 0.24 10.2 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF2427 PF10348.9 GAM24818.1 - 0.17 11.7 1.4 0.29 10.9 1.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) SPC25 PF06703.11 GAM24818.1 - 0.23 11.2 0.3 0.38 10.5 0.3 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) YfhO PF09586.10 GAM24818.1 - 0.5 8.5 1.8 0.62 8.2 1.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2721 PF11026.8 GAM24818.1 - 0.86 9.5 5.1 0.098 12.5 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF4131 PF13567.6 GAM24818.1 - 3.9 7.1 10.0 0.96 9.1 2.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Sel1 PF08238.12 GAM24819.1 - 1.4e-23 82.7 17.7 0.00025 21.6 1.4 6.0 6 0 0 6 6 6 5 Sel1 repeat CobU PF02283.16 GAM24819.1 - 0.056 13.0 0.3 0.13 11.8 0.3 1.6 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TOM20_plant PF06552.12 GAM24819.1 - 2.3 7.9 6.4 1.4 8.6 0.0 3.4 4 1 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Coiled PF05710.12 GAM24820.1 - 0.00017 22.4 7.7 0.00019 22.2 7.7 1.1 1 0 0 1 1 1 1 Coiled coil F-box PF00646.33 GAM24821.1 - 0.016 15.1 0.4 0.17 11.8 0.1 2.6 2 0 0 2 2 2 0 F-box domain CHASE3 PF05227.13 GAM24822.1 - 0.011 15.6 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 CHASE3 domain Coiled PF05710.12 GAM24823.1 - 0.0032 18.3 4.7 0.0037 18.0 4.7 1.2 1 0 0 1 1 1 1 Coiled coil DUF1786 PF08735.10 GAM24824.1 - 0.096 11.9 0.0 0.26 10.5 0.0 1.7 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) SICA_C PF12879.7 GAM24826.1 - 0.008 16.2 0.1 0.034 14.2 0.1 1.9 1 1 0 1 1 1 1 SICA C-terminal inner membrane domain RRM_1 PF00076.22 GAM24826.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NigD_N PF12667.7 GAM24826.1 - 0.081 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 NigD-like N-terminal OB domain Adaptin_N PF01602.20 GAM24827.1 - 4.1e-06 25.6 1.1 1.1e-05 24.3 1.1 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 GAM24827.1 - 6.5e-05 22.9 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region TPR_2 PF07719.17 GAM24828.1 - 0.00021 21.2 0.1 0.5 10.6 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM24828.1 - 0.0068 16.7 0.0 0.043 14.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM24828.1 - 0.008 16.0 0.4 34 4.5 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat REJ PF02010.15 GAM24829.1 - 1.8e-47 162.2 14.7 1.6e-44 152.5 4.6 2.9 3 0 0 3 3 3 2 REJ domain Glycos_transf_2 PF00535.26 GAM24829.1 - 4.4e-24 85.2 0.1 8.5e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 TIG PF01833.24 GAM24829.1 - 3.5e-12 46.2 1.4 2.9e-11 43.3 0.5 3.2 2 0 0 2 2 2 1 IPT/TIG domain GPS PF01825.21 GAM24829.1 - 5.7e-12 46.0 7.2 1.2e-11 44.9 7.2 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Glyco_trans_4_4 PF13579.6 GAM24829.1 - 6.2e-12 46.2 0.0 1.4e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 GAM24829.1 - 6.9e-12 45.7 0.5 1.9e-11 44.3 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_tranf_2_3 PF13641.6 GAM24829.1 - 8.7e-11 42.1 1.2 4.4e-10 39.8 0.2 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GAM24829.1 - 5.6e-09 35.9 0.1 9e-08 31.9 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAM24829.1 - 0.001 18.6 0.0 0.0042 16.6 0.0 2.0 1 1 1 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_1 PF00534.20 GAM24829.1 - 0.0015 18.1 0.1 0.31 10.5 0.0 3.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAM24829.1 - 0.0039 17.6 0.0 7.6 7.0 0.0 3.1 2 1 1 3 3 3 1 Glycosyl transferases group 1 EphA2_TM PF14575.6 GAM24829.1 - 0.0081 17.0 0.0 0.018 15.9 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF2827 PF10933.8 GAM24829.1 - 0.0094 14.7 0.0 0.054 12.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2827) Glyco_transf_5 PF08323.11 GAM24829.1 - 0.011 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain Insulin_TMD PF17870.1 GAM24829.1 - 0.029 14.4 0.4 0.07 13.2 0.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment IQ PF00612.27 GAM24829.1 - 0.055 13.3 2.9 0.14 12.0 2.9 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Y_Y_Y PF07495.13 GAM24829.1 - 0.064 13.2 0.0 1.1 9.2 0.0 2.8 2 0 0 2 2 2 0 Y_Y_Y domain OSTbeta PF15048.6 GAM24829.1 - 0.065 13.4 0.3 0.16 12.1 0.3 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein V-set PF07686.17 GAM24829.1 - 0.17 12.1 0.5 7.4 6.8 0.0 3.4 3 0 0 3 3 3 0 Immunoglobulin V-set domain FAM176 PF14851.6 GAM24829.1 - 0.55 9.9 2.9 0.32 10.6 0.1 2.0 2 0 0 2 2 2 0 FAM176 family Big_5 PF13205.6 GAM24829.1 - 0.59 10.9 17.6 1.2 9.9 0.4 5.9 4 1 1 6 6 6 0 Bacterial Ig-like domain TAF4 PF05236.14 GAM24829.1 - 4.2 7.0 13.5 7.3 6.3 13.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family NPR3 PF03666.13 GAM24829.1 - 6.6 5.4 6.9 13 4.4 6.9 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AA_permease_2 PF13520.6 GAM24830.1 - 8.2e-29 100.7 57.9 1.1e-28 100.3 57.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM24830.1 - 2.3e-24 85.9 50.0 3e-24 85.5 50.0 1.0 1 0 0 1 1 1 1 Amino acid permease FNIP PF05725.12 GAM24831.1 - 2.2e-39 133.3 22.7 1.2e-13 51.0 0.6 7.3 5 2 2 7 7 7 7 FNIP Repeat ECH_1 PF00378.20 GAM24834.1 - 1.5e-70 237.4 0.3 2.1e-70 236.9 0.3 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM24834.1 - 4.5e-33 115.2 2.3 2.4e-29 102.9 0.4 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CobA_CobO_BtuR PF02572.15 GAM24834.1 - 0.074 13.3 0.1 11 6.2 0.1 3.0 3 0 0 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Peptidase_S49 PF01343.18 GAM24834.1 - 0.084 12.8 0.6 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 Fringe PF02434.16 GAM24835.1 - 5.5e-14 52.2 1.5 5.5e-13 48.9 1.5 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 GAM24835.1 - 0.00021 21.1 0.2 0.00066 19.6 0.0 1.8 2 0 0 2 2 2 1 Galactosyltransferase SpoU_methylase PF00588.19 GAM24836.1 - 1.5e-27 96.5 0.0 2.9e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family RTBV_P12 PF06361.11 GAM24836.1 - 0.53 10.7 2.8 2.9 8.3 0.0 2.9 2 1 1 3 3 3 0 Rice tungro bacilliform virus P12 protein Hexapep PF00132.24 GAM24838.1 - 6.6e-12 44.7 6.7 2.7e-06 26.9 1.1 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAM24838.1 - 3e-07 30.1 6.7 0.00087 19.0 0.2 3.7 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 GAM24838.1 - 0.0087 15.0 0.3 0.87 8.5 0.0 2.1 1 1 0 2 2 2 2 L-fucokinase Coiled PF05710.12 GAM24839.1 - 7e-05 23.6 6.6 7.9e-05 23.4 6.6 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 GAM24840.1 - 3.1e-07 31.1 9.0 3.3e-07 31.0 9.0 1.0 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 GAM24841.1 - 1.5e-06 29.0 3.9 1.6e-06 28.8 3.9 1.0 1 0 0 1 1 1 1 Coiled coil RT_RNaseH_2 PF17919.1 GAM24842.1 - 4.1e-26 90.9 0.0 1e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAM24842.1 - 6.4e-26 90.7 0.0 1.6e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAM24842.1 - 5.9e-19 68.5 0.4 1.3e-17 64.1 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GAM24842.1 - 8.9e-06 25.7 0.1 8.9e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_2 PF07727.14 GAM24842.1 - 0.0086 15.7 2.0 2.2 7.8 0.2 3.7 2 2 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GAM24842.1 - 0.095 12.9 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger FH2 PF02181.23 GAM24844.1 - 3.7e-78 263.3 6.8 3.7e-78 263.3 6.8 2.4 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 GAM24844.1 - 4.7e-42 143.7 0.3 4.7e-42 143.7 0.3 2.5 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAM24844.1 - 4.8e-21 75.3 0.2 1.7e-20 73.4 0.2 2.0 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF3361 PF11841.8 GAM24844.1 - 1.1e-05 25.4 0.3 3.8e-05 23.7 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Glyco_hydro_71 PF03659.14 GAM24845.1 - 5.9e-30 104.3 4.1 9.6e-30 103.6 4.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Cellulase PF00150.18 GAM24846.1 - 2.3e-38 132.3 0.0 3.3e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ndc1_Nup PF09531.10 GAM24846.1 - 0.14 10.8 2.7 0.18 10.5 2.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC2_membrane_3 PF12698.7 GAM24847.1 - 0.12 11.5 0.4 0.13 11.3 0.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein WD40 PF00400.32 GAM24848.1 - 2.1e-06 28.4 3.9 3.5e-05 24.5 0.4 3.2 2 1 0 2 2 2 1 WD domain, G-beta repeat CRT10 PF08728.10 GAM24848.1 - 5.7e-06 24.8 0.3 5.7e-06 24.8 0.3 3.6 2 1 0 3 3 3 1 CRT10 DUF775 PF05603.12 GAM24848.1 - 0.00039 20.0 0.5 0.98 8.9 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF775) ANAPC4_WD40 PF12894.7 GAM24848.1 - 0.00059 20.1 0.1 0.003 17.8 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM24848.1 - 0.0039 15.9 0.1 0.014 14.1 0.3 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Dicty_REP PF05086.12 GAM24848.1 - 0.01 13.9 5.2 0.015 13.3 5.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PH_8 PF15409.6 GAM24848.1 - 0.1 12.9 0.0 10 6.5 0.0 2.7 1 1 1 2 2 2 0 Pleckstrin homology domain Zip PF02535.22 GAM24848.1 - 0.2 10.8 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cwf_Cwc_15 PF04889.12 GAM24848.1 - 0.33 10.7 15.7 0.48 10.1 15.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Spt20 PF12090.8 GAM24848.1 - 1 8.9 13.1 1.6 8.3 13.1 1.2 1 0 0 1 1 1 0 Spt20 family RPN2_C PF18004.1 GAM24848.1 - 1.2 9.1 8.7 1.9 8.4 8.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 GAM24848.1 - 1.2 7.3 15.9 1.5 6.9 15.9 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GAM24848.1 - 5.1 5.1 17.9 6.9 4.6 17.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 GAM24848.1 - 6 6.4 19.1 9 5.8 19.1 1.2 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 GAM24848.1 - 7.7 5.2 6.2 11 4.7 6.2 1.2 1 0 0 1 1 1 0 Presenilin PUF PF00806.19 GAM24851.1 - 3.4e-56 183.9 11.5 6e-09 35.1 0.1 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Torus PF16131.5 GAM24851.1 - 4.9e-05 24.0 0.1 4.9e-05 24.0 0.1 4.3 3 2 0 3 3 3 1 Torus domain zf-CCCH PF00642.24 GAM24851.1 - 0.00022 21.0 3.4 0.00063 19.6 3.4 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAM24851.1 - 0.00078 19.2 4.7 0.00078 19.2 4.7 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger TFIIA PF03153.13 GAM24851.1 - 0.00079 19.5 41.8 0.00079 19.5 41.8 3.0 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf_CCCH_4 PF18345.1 GAM24851.1 - 0.0058 16.7 8.3 0.014 15.4 8.3 1.7 1 0 0 1 1 1 1 Zinc finger domain RNB PF00773.19 GAM24852.1 - 7.7e-27 94.5 7.8 7.7e-27 94.5 7.8 1.7 2 0 0 2 2 2 1 RNB domain AAA_11 PF13086.6 GAM24852.1 - 1.3e-18 67.8 0.6 9.4e-09 35.4 0.1 3.1 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.6 GAM24852.1 - 1.7e-11 44.1 0.0 5.3e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM24852.1 - 0.0032 17.2 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 GAM24852.1 - 0.005 17.4 0.8 0.038 14.5 0.0 2.7 2 2 1 3 3 3 1 AAA domain Desmo_N PF06771.11 GAM24852.1 - 0.025 14.9 0.3 0.82 10.1 0.1 3.1 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus AAA_25 PF13481.6 GAM24852.1 - 0.027 14.0 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 GAM24852.1 - 0.044 13.2 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein DUF2732 PF10809.8 GAM24852.1 - 0.17 11.8 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) PH PF00169.29 GAM24853.1 - 6.2e-19 68.4 0.0 1.9e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM24853.1 - 0.00059 20.1 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 GAM24853.1 - 0.0092 16.1 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 GAM24853.1 - 0.015 15.6 0.1 2.6 8.4 0.0 3.1 2 0 0 2 2 2 0 Pleckstrin homology domain CorA PF01544.18 GAM24853.1 - 0.067 12.5 2.0 6.3 6.0 1.6 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DDE_Tnp_IS240 PF13610.6 GAM24853.1 - 0.46 10.7 3.7 0.16 12.2 0.5 1.9 2 0 0 2 2 2 0 DDE domain DUF1674 PF07896.12 GAM24854.1 - 2.4e-18 66.3 4.0 3.7e-18 65.7 3.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) YARHG PF13308.6 GAM24854.1 - 0.011 15.6 0.2 0.016 15.1 0.2 1.3 1 0 0 1 1 1 0 YARHG domain DUF5595 PF18077.1 GAM24854.1 - 0.025 14.6 0.4 0.036 14.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) PspB PF06667.12 GAM24854.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Phage shock protein B Ank_2 PF12796.7 GAM24855.1 - 0.01 16.4 0.3 1.5 9.5 0.0 3.4 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM24855.1 - 0.036 14.4 0.1 10 6.5 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DASH_Dam1 PF08653.10 GAM24855.1 - 0.3 10.9 1.6 10 6.0 0.1 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 AAA_31 PF13614.6 GAM24856.1 - 2.6e-20 73.1 0.0 4.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 GAM24856.1 - 1e-15 57.9 0.0 1.4e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 GAM24856.1 - 2.1e-15 56.9 0.1 1.8e-14 53.8 0.1 2.2 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 GAM24856.1 - 1.2e-09 37.8 0.0 2e-09 37.1 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 GAM24856.1 - 1.5e-06 27.6 0.6 4.3e-06 26.1 0.3 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 GAM24856.1 - 2.5e-06 27.1 0.0 3.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 GAM24856.1 - 5.5e-05 22.8 0.1 0.35 10.3 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 GAM24856.1 - 0.00049 19.9 0.2 0.00094 18.9 0.2 1.5 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 GAM24856.1 - 0.001 18.7 0.4 1.1 8.8 0.2 2.3 2 1 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_7 PF12775.7 GAM24856.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region CLP1_P PF16575.5 GAM24856.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.7 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_26 PF13500.6 GAM24856.1 - 0.15 11.8 0.5 3.7 7.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 GAM24856.1 - 0.24 10.7 0.8 0.38 10.1 0.8 1.5 1 1 0 1 1 1 0 KaiC Ras PF00071.22 GAM24857.1 - 1.2e-64 216.8 0.4 1.4e-64 216.6 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24857.1 - 2.1e-36 124.7 0.1 3.8e-36 123.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24857.1 - 6.6e-16 58.3 0.0 8.2e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM24857.1 - 1.7e-06 27.5 0.0 2.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAM24857.1 - 8e-06 25.9 0.3 0.12 12.2 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAM24857.1 - 1.3e-05 24.8 0.3 3.1e-05 23.6 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM24857.1 - 4.9e-05 23.4 0.0 0.00018 21.6 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAM24857.1 - 0.00095 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 GAM24857.1 - 0.015 15.7 0.0 0.57 10.6 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 GAM24857.1 - 0.041 13.6 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM24857.1 - 0.057 13.8 0.0 0.096 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAM24857.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 GAM24857.1 - 0.063 13.0 0.2 0.38 10.5 0.2 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 GAM24857.1 - 0.086 12.8 0.0 0.1 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAM24857.1 - 0.099 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 GAM24857.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 GAM24857.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Glyco_transf_49 PF13896.6 GAM24858.1 - 1.1e-48 166.3 2.7 2.1e-38 132.5 1.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAM24858.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 FNIP PF05725.12 GAM24859.1 - 3.2e-18 65.6 12.0 0.00016 21.8 0.0 6.7 8 0 0 8 8 8 5 FNIP Repeat TPR_2 PF07719.17 GAM24860.1 - 2.2e-46 152.3 32.1 3.8e-06 26.6 0.0 18.2 20 0 0 20 20 20 8 Tetratricopeptide repeat TPR_1 PF00515.28 GAM24860.1 - 3.2e-43 143.8 31.1 1.4e-07 31.0 0.2 15.9 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_19 PF14559.6 GAM24860.1 - 4.2e-40 136.1 15.5 1.8e-09 38.0 0.0 11.5 6 2 4 12 12 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 GAM24860.1 - 1.9e-31 105.6 24.6 1.7e-05 24.7 0.0 15.7 17 0 0 17 17 14 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAM24860.1 - 1.3e-29 100.3 9.2 0.00087 19.9 0.0 14.2 9 4 7 16 16 14 7 Tetratricopeptide repeat TPR_16 PF13432.6 GAM24860.1 - 1.8e-27 95.7 12.4 1.2e-08 35.4 0.0 10.9 11 2 2 13 13 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM24860.1 - 4.3e-27 94.2 34.4 1.3e-07 31.8 0.1 12.3 11 4 2 13 13 12 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAM24860.1 - 4.9e-27 91.9 11.1 0.0032 17.4 0.0 12.5 14 0 0 14 14 12 7 Tetratricopeptide repeat TPR_17 PF13431.6 GAM24860.1 - 5.8e-27 92.1 21.6 0.058 13.8 0.0 14.3 15 0 0 15 15 14 7 Tetratricopeptide repeat TPR_11 PF13414.6 GAM24860.1 - 1.7e-22 78.8 32.6 1.3e-06 27.9 0.1 12.2 10 4 4 14 14 14 5 TPR repeat TPR_6 PF13174.6 GAM24860.1 - 2.6e-21 74.8 22.1 0.0007 20.1 0.0 12.1 15 0 0 15 15 11 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAM24860.1 - 3.9e-17 62.1 0.0 1.1e-06 28.6 0.0 5.5 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAM24860.1 - 5.1e-12 45.2 21.6 0.17 11.8 0.0 11.2 12 0 0 12 12 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM24860.1 - 1.1e-10 41.6 22.0 0.087 13.1 0.0 8.5 4 3 5 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 GAM24860.1 - 0.00026 21.0 6.1 1.3 9.5 0.0 6.2 6 0 0 6 6 5 1 PPR repeat TPR_4 PF07721.14 GAM24860.1 - 0.001 19.5 0.1 47 5.0 0.0 6.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM24860.1 - 0.0025 17.8 18.8 0.37 10.9 1.4 7.1 7 1 1 8 8 8 2 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 GAM24860.1 - 0.0032 17.8 11.3 0.16 12.3 0.0 7.0 8 2 1 10 10 6 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 GAM24860.1 - 0.0036 17.4 0.2 0.093 12.8 0.0 3.4 3 0 0 3 3 2 1 Rapsyn N-terminal myristoylation and linker region RPN7 PF10602.9 GAM24860.1 - 0.0058 16.4 0.2 0.0058 16.4 0.2 6.6 6 2 1 7 7 6 1 26S proteasome subunit RPN7 NARP1 PF12569.8 GAM24860.1 - 0.14 11.0 0.0 0.062 12.2 0.6 7.6 3 2 4 8 8 5 0 NMDA receptor-regulated protein 1 SRP-alpha_N PF04086.13 GAM24860.1 - 1.2 9.0 34.1 1.9 8.4 34.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TPR_3 PF07720.12 GAM24860.1 - 1.9 8.5 10.7 1.6 8.8 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat FNIP PF05725.12 GAM24861.1 - 7.3e-25 86.9 14.6 2.1e-07 31.0 0.1 6.8 4 3 5 9 9 9 7 FNIP Repeat FNIP PF05725.12 GAM24862.1 - 2.2e-19 69.3 16.4 4.2e-13 49.2 0.1 7.5 6 2 2 9 9 9 5 FNIP Repeat LRR_4 PF12799.7 GAM24862.1 - 0.14 12.6 12.6 9.4 6.8 0.0 5.5 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 GAM24863.1 - 1.1e-15 57.5 20.4 2.8e-10 40.2 0.0 7.4 6 2 2 9 9 9 5 FNIP Repeat FNIP PF05725.12 GAM24864.1 - 6.1e-19 67.9 7.9 8.4e-08 32.3 0.0 7.5 5 3 2 7 7 7 5 FNIP Repeat Methyltransf_4 PF02390.17 GAM24864.1 - 0.051 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MSP7_C PF12948.7 GAM24864.1 - 0.11 13.2 2.3 0.18 12.5 2.3 1.3 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain DrsE PF02635.15 GAM24865.1 - 1.2e-05 25.6 0.0 1.4e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF-like family Cofilin_ADF PF00241.20 GAM24866.1 - 2.4e-18 66.1 0.7 2.7e-18 65.9 0.7 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FNIP PF05725.12 GAM24868.1 - 4.4e-21 74.8 10.2 6.2e-14 51.9 0.2 6.1 4 2 2 6 6 6 5 FNIP Repeat FNIP PF05725.12 GAM24869.1 - 1.7e-24 85.7 2.1 4.2e-09 36.4 0.0 6.8 4 2 5 9 9 9 6 FNIP Repeat FNIP PF05725.12 GAM24870.1 - 8.2e-23 80.3 5.6 9.6e-08 32.1 0.4 6.2 4 1 1 6 6 6 4 FNIP Repeat FNIP PF05725.12 GAM24872.1 - 3.3e-12 46.3 12.6 4.9e-06 26.6 2.7 6.4 5 2 1 6 6 6 5 FNIP Repeat Pkinase PF00069.25 GAM24873.1 - 1.8e-63 214.4 0.1 2.2e-62 210.8 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24873.1 - 1.5e-28 99.8 0.2 1e-20 74.1 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 GAM24873.1 - 3.3e-05 24.5 0.0 0.0001 22.9 0.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 GAM24873.1 - 0.00023 20.2 0.8 0.00034 19.7 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM24873.1 - 0.0011 18.9 0.8 0.1 12.5 0.4 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAM24873.1 - 0.0036 16.7 0.6 0.023 14.0 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 GAM24873.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 NADPH_Ox PF08414.10 GAM24873.1 - 0.059 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase RhoGEF PF00621.20 GAM24874.1 - 2e-47 161.8 8.0 8.6e-47 159.7 8.0 2.2 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAM24874.1 - 4.6e-28 97.8 5.8 1.1e-14 54.9 0.2 4.0 4 0 0 4 4 4 3 PH domain ArfGap PF01412.18 GAM24874.1 - 3.3e-21 75.5 0.1 1.6e-20 73.3 0.1 2.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CH PF00307.31 GAM24874.1 - 4.9e-18 65.3 2.4 6.7e-18 64.9 0.1 2.5 3 0 0 3 3 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM24874.1 - 0.00021 21.1 0.0 0.00067 19.4 0.0 2.0 1 0 0 1 1 1 1 CAMSAP CH domain PH_11 PF15413.6 GAM24874.1 - 0.0012 19.3 16.4 0.0028 18.0 3.4 5.5 3 2 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 GAM24874.1 - 0.037 14.3 0.1 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 GAM24874.1 - 0.045 14.1 1.3 27 5.2 0.0 3.8 4 0 0 4 4 3 0 Plant pleckstrin homology-like region PH_13 PF16652.5 GAM24874.1 - 0.056 13.3 11.1 1.1 9.1 2.9 4.8 4 1 0 4 4 4 0 Pleckstrin homology domain CH_2 PF06294.11 GAM24874.1 - 0.12 12.5 0.8 0.63 10.2 0.0 2.7 3 0 0 3 3 2 0 CH-like domain in sperm protein PH_6 PF15406.6 GAM24874.1 - 0.34 11.2 0.0 0.34 11.2 0.0 3.0 3 0 0 3 3 2 0 Pleckstrin homology domain Velvet PF11754.8 GAM24874.1 - 0.78 9.6 7.1 16 5.4 0.1 2.9 2 1 0 2 2 2 0 Velvet factor IQ PF00612.27 GAM24874.1 - 1.8 8.6 7.5 1.3 9.0 2.2 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF2722 PF10846.8 GAM24874.1 - 2.9 6.7 16.5 1.1 8.1 8.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) G8 PF10162.9 GAM24875.1 - 2.2e-23 82.7 1.5 4.7e-23 81.6 0.7 2.0 2 0 0 2 2 2 1 G8 domain G8 PF10162.9 GAM24877.1 - 1.6e-23 83.1 0.5 4.1e-23 81.8 0.5 1.7 1 0 0 1 1 1 1 G8 domain Amnionless PF14828.6 GAM24877.1 - 0.026 13.3 0.1 0.042 12.7 0.1 1.2 1 0 0 1 1 1 0 Amnionless Beta_helix PF13229.6 GAM24877.1 - 0.65 9.8 17.0 0.14 12.0 4.3 3.7 2 1 0 3 3 3 0 Right handed beta helix region Glyoxalase PF00903.25 GAM24878.1 - 7.4e-22 77.9 2.8 6e-16 58.8 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAM24878.1 - 1.1e-10 41.7 0.2 0.00015 22.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 GAM24878.1 - 1.7e-06 28.3 0.0 3.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 GAM24878.1 - 7e-06 26.3 0.6 0.0072 16.5 0.5 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain FNIP PF05725.12 GAM24879.1 - 8.8e-19 67.4 7.4 2.8e-08 33.8 0.0 6.7 4 3 3 7 7 7 6 FNIP Repeat CM2 PF03021.14 GAM24882.1 - 0.12 12.2 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 Influenza C virus M2 protein Ank_2 PF12796.7 GAM24884.1 - 0.0084 16.7 1.8 0.49 11.0 0.2 3.2 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM24884.1 - 0.21 12.3 1.1 4.3e+02 2.1 0.0 4.8 4 0 0 4 4 4 0 Ankyrin repeat pKID PF02173.17 GAM24885.1 - 0.12 11.9 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 pKID domain HATPase_c_3 PF13589.6 GAM24886.1 - 0.0018 18.1 4.8 0.56 10.0 0.4 4.1 3 2 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Actin PF00022.19 GAM24890.1 - 2e-09 36.6 0.0 2.6e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Actin NADH_Oxid_Nqo15 PF11497.8 GAM24890.1 - 0.067 13.2 0.2 0.096 12.7 0.2 1.2 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 Blt1 PF12754.7 GAM24890.1 - 0.087 13.1 2.7 0.12 12.7 2.7 1.2 1 0 0 1 1 1 0 Blt1 N-terminal domain IFP_35_N PF07334.13 GAM24890.1 - 0.18 11.9 1.8 0.29 11.2 1.8 1.3 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Uma2 PF05685.12 GAM24893.1 - 2.1e-06 27.4 0.0 5.9e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Putative restriction endonuclease DP PF08781.10 GAM24893.1 - 0.029 14.3 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 Transcription factor DP HATPase_c_3 PF13589.6 GAM24895.1 - 0.025 14.4 0.3 0.24 11.2 0.3 2.3 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_WhiA PF02650.14 GAM24896.1 - 0.045 14.1 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 WhiA C-terminal HTH domain Chal_sti_synt_N PF00195.19 GAM24897.1 - 5.5e-28 97.9 0.2 8.7e-28 97.3 0.2 1.3 1 1 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 GAM24897.1 - 3.9e-11 43.2 0.0 8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 GAM24897.1 - 9.6e-09 34.9 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 GAM24897.1 - 0.00019 21.6 0.0 0.00095 19.3 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 GAM24897.1 - 0.00023 20.9 0.5 0.00066 19.5 0.5 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GATase1_like PF07090.11 GAM24898.1 - 0.069 12.6 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative glutamine amidotransferase Peptidase_C39 PF03412.15 GAM24899.1 - 0.0086 15.9 0.3 0.073 12.9 0.3 2.1 1 1 1 2 2 2 1 Peptidase C39 family Fn3_assoc PF13287.6 GAM24899.1 - 0.086 13.0 0.8 0.086 13.0 0.8 2.7 3 0 0 3 3 3 0 Fn3 associated DUF4470 PF14737.6 GAM24900.1 - 2.5e-08 34.0 0.0 7.8e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_1 PF00515.28 GAM24900.1 - 2.3e-06 27.2 0.5 0.026 14.3 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM24900.1 - 1.1e-05 25.2 0.2 0.016 15.3 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM24900.1 - 7e-05 22.4 1.1 0.00096 18.8 0.2 2.6 1 1 1 2 2 2 1 TPR repeat TPR_12 PF13424.6 GAM24900.1 - 7.3e-05 23.0 1.0 0.0034 17.6 0.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM24900.1 - 0.0025 17.9 0.4 2.8 8.4 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM24900.1 - 0.0043 17.5 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM24900.1 - 0.11 13.2 0.0 0.34 11.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM24900.1 - 0.15 12.3 0.6 14 6.0 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAM24900.1 - 0.36 11.3 1.6 1.1 9.8 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat PPP4R2 PF09184.11 GAM24900.1 - 0.72 9.4 16.8 1.3 8.6 16.8 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 GAM24900.1 - 0.96 8.7 21.6 1.6 8.0 21.6 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 GAM24900.1 - 1.6 8.4 20.2 4.9 6.8 20.2 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 GAM24900.1 - 7.9 6.4 14.6 14 5.6 14.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4470 PF14737.6 GAM24901.1 - 4.4e-10 39.6 0.0 1.3e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 GAM24901.1 - 2.9e-07 30.1 0.1 2.3e-05 24.0 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 GAM24901.1 - 1.8e-06 27.6 0.1 0.00016 21.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM24901.1 - 5.7e-06 25.9 0.7 0.0012 18.6 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM24901.1 - 0.035 14.9 0.0 0.14 13.1 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM24901.1 - 0.14 12.5 0.2 24 5.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM24901.1 - 0.15 12.6 0.0 0.45 11.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM24901.1 - 0.17 12.2 0.2 4.3 7.7 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4470 PF14737.6 GAM24902.1 - 5.4e-10 39.3 0.1 1.7e-09 37.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 GAM24902.1 - 2.8e-06 27.0 1.1 2.5e-05 24.1 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM24902.1 - 1e-05 25.1 1.8 9.8e-05 22.0 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAM24902.1 - 1.4e-05 24.7 0.1 3.7e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.6 GAM24902.1 - 0.00045 20.8 0.0 0.0028 18.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM24902.1 - 0.00086 19.5 0.1 0.01 16.1 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM24902.1 - 0.067 13.8 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM24902.1 - 0.07 13.7 0.0 0.25 11.9 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SnoaL_2 PF12680.7 GAM24903.1 - 1.9e-05 25.3 0.0 2.2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 GAM24903.1 - 0.0032 17.3 0.3 0.0061 16.4 0.3 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 GAM24903.1 - 0.038 14.4 0.0 0.046 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Adaptin_N PF01602.20 GAM24904.1 - 1.5e-136 456.0 24.1 2.7e-136 455.2 24.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAM24904.1 - 4.3e-25 88.6 18.0 7.7e-21 74.8 2.5 4.1 5 0 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 GAM24904.1 - 5.3e-13 49.5 0.2 1.8e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.6 GAM24904.1 - 1.1e-12 48.2 1.0 1.2e-05 25.5 0.3 4.3 2 2 1 3 3 3 2 HEAT repeats HEAT PF02985.22 GAM24904.1 - 1.7e-07 30.9 6.5 0.022 15.0 0.0 6.0 7 0 0 7 7 5 2 HEAT repeat HEAT_EZ PF13513.6 GAM24904.1 - 8.6e-07 29.3 0.8 0.17 12.4 0.0 5.1 4 1 1 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.7 GAM24904.1 - 0.0044 17.3 2.6 0.62 10.4 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion GUN4_N PF16416.5 GAM24904.1 - 0.031 14.3 0.3 0.85 9.7 0.0 3.3 3 0 0 3 3 2 0 ARM-like repeat domain, GUN4-N terminal Svf1_C PF17187.4 GAM24904.1 - 0.031 14.1 1.0 0.18 11.6 0.2 2.5 2 0 0 2 2 2 0 Svf1-like C-terminal lipocalin-like domain GAGA_bind PF06217.12 GAM24904.1 - 0.19 12.0 0.8 0.42 10.9 0.8 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family DUF760 PF05542.11 GAM24904.1 - 0.47 10.8 4.3 3.6 8.0 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF760) YL1 PF05764.13 GAM24904.1 - 3.2 7.8 16.7 8.4 6.4 16.7 1.7 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 GAM24904.1 - 3.2 5.8 18.5 6.6 4.8 18.5 1.4 1 0 0 1 1 1 0 Nop14-like family MecA PF05389.12 GAM24904.1 - 4.4 6.9 13.8 14 5.2 10.1 3.2 2 1 0 2 2 2 0 Negative regulator of genetic competence (MecA) CDC45 PF02724.14 GAM24904.1 - 7 4.8 14.9 18 3.5 14.9 1.6 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 GAM24905.1 - 5.9e-76 255.3 0.3 7.6e-76 255.0 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24905.1 - 2e-36 125.6 0.0 2.8e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM24905.1 - 2.7e-09 36.7 0.0 3.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAM24905.1 - 2.8e-07 29.8 0.7 2.8e-07 29.8 0.7 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM24905.1 - 7.4e-06 25.0 0.0 1.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAM24905.1 - 0.0019 17.6 0.1 0.0037 16.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM24905.1 - 0.0035 17.0 0.2 0.0067 16.0 0.2 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 GAM24905.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 GAM24905.1 - 0.022 15.5 2.0 0.2 12.4 2.0 2.6 1 1 0 1 1 1 0 Protein kinase C terminal domain Ammonium_transp PF00909.21 GAM24906.1 - 7.9e-106 354.1 29.3 9.1e-106 353.9 29.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family BT1 PF03092.16 GAM24906.1 - 0.0037 15.6 1.6 0.0078 14.5 1.6 1.6 1 0 0 1 1 1 1 BT1 family Adeno_E3_CR2 PF02439.15 GAM24906.1 - 1.8 8.4 6.9 10 6.0 1.4 3.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Aldose_epim PF01263.20 GAM24907.1 - 5e-50 170.5 0.1 6e-50 170.3 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase YmaF PF12788.7 GAM24908.1 - 0.024 15.1 2.0 0.067 13.7 2.0 1.8 1 0 0 1 1 1 0 YmaF family SURF1 PF02104.15 GAM24909.1 - 1e-37 130.1 0.0 1.2e-37 129.9 0.0 1.0 1 0 0 1 1 1 1 SURF1 family cobW PF02492.19 GAM24910.1 - 1e-53 181.6 0.7 1.6e-53 181.0 0.7 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAM24910.1 - 9.3e-24 83.2 0.0 2.1e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain dbPDZ_assoc PF16610.5 GAM24910.1 - 0.0067 16.6 1.6 3.6 7.9 0.6 2.6 2 0 0 2 2 2 2 Unstructured region between two PDZ domains on Dlg5 RsgA_GTPase PF03193.16 GAM24910.1 - 0.0076 16.2 5.9 0.046 13.6 0.1 3.0 3 0 0 3 3 3 1 RsgA GTPase MobB PF03205.14 GAM24910.1 - 0.0097 15.8 0.3 0.056 13.3 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 GAM24910.1 - 0.025 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 GAM24910.1 - 0.055 13.2 0.4 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 GAM24910.1 - 0.066 13.6 0.3 0.52 10.7 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain CDC45 PF02724.14 GAM24910.1 - 0.087 11.1 12.7 0.12 10.6 12.7 1.2 1 0 0 1 1 1 0 CDC45-like protein MMR_HSR1 PF01926.23 GAM24910.1 - 0.13 12.3 1.8 0.28 11.3 0.3 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 GAM24910.1 - 0.14 12.0 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 GAM24910.1 - 0.15 12.6 1.9 0.26 11.8 0.1 2.1 2 1 0 2 2 2 0 ABC transporter SH3_9 PF14604.6 GAM24911.1 - 7.2e-14 51.4 0.1 1.3e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM24911.1 - 3.6e-11 42.5 0.1 6.9e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM24911.1 - 5e-09 35.7 0.0 9.3e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DivIC PF04977.15 GAM24911.1 - 0.0084 15.9 4.2 0.0084 15.9 4.2 2.7 2 0 0 2 2 2 1 Septum formation initiator HIP1_clath_bdg PF16515.5 GAM24911.1 - 0.012 16.3 6.5 0.012 16.3 6.5 3.4 3 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Med19 PF10278.9 GAM24911.1 - 0.43 10.5 16.3 0.061 13.3 3.4 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF5320 PF17253.2 GAM24911.1 - 0.51 11.4 7.2 3.2 8.9 3.0 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5320) U1snRNP70_N PF12220.8 GAM24911.1 - 0.98 10.1 17.3 0.075 13.7 3.5 3.4 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF1664 PF07889.12 GAM24911.1 - 9.5 6.3 10.0 4 7.5 3.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ICMT PF04140.14 GAM24912.1 - 3.4e-28 97.9 0.0 6.7e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 GAM24912.1 - 1.1e-09 38.6 0.1 1.1e-09 38.6 0.1 2.9 2 2 1 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 GAM24912.1 - 0.0035 16.9 3.3 0.0036 16.9 2.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Peptidase_C54 PF03416.19 GAM24913.1 - 7.5e-86 288.0 1.1 7.5e-86 288.0 1.1 2.2 2 1 0 2 2 2 1 Peptidase family C54 SelK_SelG PF10961.8 GAM24914.1 - 0.082 13.5 0.3 0.082 13.5 0.3 1.1 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Na_Ca_ex PF01699.24 GAM24915.1 - 4.5e-22 78.6 33.8 6.8e-14 52.1 8.9 4.0 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 GAM24915.1 - 1.8e-14 54.2 12.1 1.8e-14 54.2 12.1 5.2 6 0 0 6 6 6 1 Inner membrane component domain PhoLip_ATPase_C PF16212.5 GAM24916.1 - 1.8e-51 175.3 22.6 1.8e-51 175.3 22.6 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM24916.1 - 3.5e-16 58.7 9.0 1.2e-15 57.0 9.0 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAM24916.1 - 6.2e-13 48.6 0.2 1.2e-10 41.3 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM24916.1 - 8.6e-12 45.8 0.1 0.001 19.4 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAM24916.1 - 9.9e-08 31.7 2.5 2.8e-07 30.2 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAM24916.1 - 0.00024 21.0 0.1 0.00024 21.0 0.1 3.3 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hum_adeno_E3A PF05393.11 GAM24916.1 - 0.051 13.5 0.6 0.18 11.8 0.6 2.0 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein PuR_N PF09182.10 GAM24916.1 - 0.14 12.1 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal Vfa1 PF08432.10 GAM24916.1 - 0.7 10.2 16.5 0.02 15.3 7.0 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.10 GAM24916.1 - 5.6 7.0 5.9 21 5.2 5.9 2.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkinase PF00069.25 GAM24917.1 - 3.2e-66 223.4 0.0 4e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM24917.1 - 5.9e-26 91.3 0.0 1e-25 90.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM24917.1 - 1.5e-05 24.5 0.0 2.4e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM24917.1 - 0.003 17.0 0.1 0.0045 16.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM24917.1 - 0.013 15.4 0.0 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM24917.1 - 0.021 14.4 0.1 0.04 13.5 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Mob1_phocein PF03637.17 GAM24918.1 - 6.7e-33 114.1 2.2 9.5e-33 113.6 2.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family CH PF00307.31 GAM24920.1 - 5.7e-14 52.2 0.0 5.7e-14 52.2 0.0 4.2 4 1 1 5 5 5 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM24920.1 - 0.02 14.7 0.0 0.09 12.6 0.0 2.1 1 0 0 1 1 1 0 CAMSAP CH domain GRAB PF10375.9 GAM24920.1 - 0.026 14.4 0.1 0.064 13.1 0.1 1.7 1 0 0 1 1 1 0 GRIP-related Arf-binding domain CBM49 PF09478.10 GAM24921.1 - 2.1e-14 53.6 5.0 4.9e-14 52.4 5.0 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 dCMP_cyt_deam_1 PF00383.23 GAM24921.1 - 1.5e-10 40.9 0.5 3.3e-10 39.7 0.5 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAM24921.1 - 3.3e-08 33.4 0.1 5.3e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 GAM24921.1 - 0.11 12.6 0.2 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 GAM24921.1 - 0.12 12.5 0.5 0.48 10.5 0.2 1.9 1 1 1 2 2 2 0 Bd3614-like deaminase BHD_3 PF10405.9 GAM24922.1 - 7.2e-22 77.6 0.1 1.7e-21 76.4 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 GAM24922.1 - 7e-20 71.2 0.2 7e-20 71.2 0.2 4.3 3 1 1 4 4 4 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 GAM24922.1 - 1.2e-08 34.7 0.0 7.8e-08 32.0 0.0 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 GAM24922.1 - 1.9e-06 28.7 2.2 1.9e-06 28.7 2.2 5.8 3 2 0 3 3 3 1 Rad4 beta-hairpin domain 2 T3SchapCesA PF11439.8 GAM24924.1 - 0.21 11.7 3.3 2.8 8.1 0.0 4.4 4 0 0 4 4 4 0 Type III secretion system filament chaperone CesA HK_sensor PF16750.5 GAM24924.1 - 0.41 11.0 4.0 30 5.0 0.2 4.3 4 0 0 4 4 4 0 Sensor domain of 2-component histidine kinase DUF1798 PF08807.10 GAM24924.1 - 0.52 10.5 6.3 0.39 10.9 0.4 4.0 4 0 0 4 4 4 0 Bacterial domain of unknown function (DUF1798) RecG_N PF17190.4 GAM24924.1 - 1.5 9.6 3.9 16 6.3 0.1 4.9 4 0 0 4 4 4 0 RecG N-terminal helical domain TIG PF01833.24 GAM24925.1 - 3.1e-18 65.6 45.0 0.00013 22.0 7.8 6.5 5 1 1 6 6 6 5 IPT/TIG domain Lectin_C PF00059.21 GAM24925.1 - 1.3e-05 25.9 0.0 4.4e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Lectin C-type domain EGF_2 PF07974.13 GAM24925.1 - 0.096 13.1 11.8 0.27 11.6 11.8 1.8 1 0 0 1 1 1 0 EGF-like domain DnaJ_CXXCXGXG PF00684.19 GAM24926.1 - 0.00036 20.8 21.8 0.023 15.0 21.8 3.0 1 1 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAM24926.1 - 0.055 13.4 14.2 2.5 8.1 0.1 3.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 GAM24926.1 - 0.54 10.5 19.0 7.1 6.9 1.2 4.2 2 2 1 3 3 3 0 Family of unknown function (DUF5351) Ribosomal_L20 PF00453.18 GAM24927.1 - 3e-35 120.5 1.5 3.8e-35 120.2 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 HTH_21 PF13276.6 GAM24927.1 - 0.0035 17.4 0.8 0.0061 16.7 0.8 1.4 1 0 0 1 1 1 1 HTH-like domain LSM PF01423.22 GAM24928.1 - 2e-19 69.0 2.7 3.1e-19 68.4 2.7 1.3 1 1 0 1 1 1 1 LSM domain HydF_dimer PF18128.1 GAM24928.1 - 0.032 14.3 0.3 0.068 13.3 0.2 1.7 1 1 0 1 1 1 0 Hydrogen maturase F dimerization domain HMMR_N PF15905.5 GAM24928.1 - 0.032 13.7 0.6 0.036 13.6 0.6 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Adap_comp_sub PF00928.21 GAM24929.1 - 6.4e-54 183.1 0.0 8.8e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ag332 PF04671.12 GAM24929.1 - 0.015 15.2 0.2 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Erythrocyte membrane-associated giant protein antigen 332 Clat_adaptor_s PF01217.20 GAM24929.1 - 0.072 13.0 0.1 0.17 11.8 0.1 1.6 1 1 0 1 1 1 0 Clathrin adaptor complex small chain TerD PF02342.18 GAM24930.1 - 3.5e-70 235.3 0.0 4.3e-70 235.0 0.0 1.0 1 0 0 1 1 1 1 TerD domain Ras PF00071.22 GAM24931.1 - 1.2e-54 184.3 0.0 1.4e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24931.1 - 9.6e-33 113.0 0.0 1.7e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24931.1 - 2.6e-17 62.8 0.1 2.8e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM24931.1 - 4.9e-06 26.1 0.0 6.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM24931.1 - 1.3e-05 24.9 0.2 6e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAM24931.1 - 5.2e-05 22.8 0.0 6.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAM24931.1 - 0.00021 21.2 0.1 0.11 12.3 0.1 2.5 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM24931.1 - 0.00052 20.1 0.0 0.00097 19.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 GAM24931.1 - 0.022 14.5 0.1 4 7.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 GAM24931.1 - 0.053 12.7 0.7 1.4 8.0 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit RNA_pol_Rpc4 PF05132.14 GAM24932.1 - 0.0083 16.6 0.8 0.011 16.1 0.8 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 Mak16 PF04874.14 GAM24932.1 - 6.1 7.5 24.8 9.4 6.9 24.8 1.2 1 0 0 1 1 1 0 Mak16 protein C-terminal region CobT PF06213.12 GAM24932.1 - 9.1 5.6 26.2 12 5.2 26.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2448 PF10476.9 GAM24933.1 - 0.13 12.1 1.2 0.15 11.9 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) DUF4614 PF15391.6 GAM24933.1 - 5.1 7.0 22.6 5.5 6.9 22.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Secretin_N_2 PF07655.13 GAM24933.1 - 5.7 7.5 26.4 9.4 6.9 26.4 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain CCDC106 PF15794.5 GAM24933.1 - 6.6 6.4 14.6 7.4 6.2 14.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 NPR2 PF06218.11 GAM24933.1 - 6.6 5.4 6.3 7.3 5.2 6.3 1.0 1 0 0 1 1 1 0 Nitrogen permease regulator 2 Macoilin PF09726.9 GAM24933.1 - 8.8 4.7 20.7 8.5 4.8 20.7 1.0 1 0 0 1 1 1 0 Macoilin family Peroxin-3 PF04882.12 GAM24933.1 - 8.9 5.2 13.0 11 4.9 13.0 1.0 1 0 0 1 1 1 0 Peroxin-3 Transketolase_N PF00456.21 GAM24934.1 - 7e-107 357.2 0.3 9.7e-107 356.8 0.3 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAM24934.1 - 1.6e-42 145.2 0.0 6e-42 143.3 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAM24934.1 - 6.5e-14 51.9 0.0 6.4e-13 48.7 0.0 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAM24934.1 - 4e-06 26.3 0.1 1.6e-05 24.2 0.1 2.0 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 GAM24934.1 - 0.0008 19.2 0.0 0.0059 16.4 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF3939 PF13075.6 GAM24934.1 - 0.0027 17.7 0.1 0.0052 16.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3939) E1_dh PF00676.20 GAM24934.1 - 0.0056 15.7 0.1 0.0091 15.0 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component UBA_3 PF09288.10 GAM24934.1 - 0.064 13.1 0.1 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain PT PF04886.12 GAM24938.1 - 4.3e-20 70.9 54.6 1.8e+04 -26.1 54.4 7.0 1 1 0 1 1 1 0 PT repeat Yae1_N PF09811.9 GAM24939.1 - 5.3e-42 141.2 30.2 1e-06 28.3 1.3 8.6 1 1 6 7 7 7 7 Essential protein Yae1, N terminal Dpy-30 PF05186.13 GAM24939.1 - 0.0062 16.2 23.0 2.5e+02 1.5 0.0 12.0 3 2 1 4 4 4 0 Dpy-30 motif CCDC117 PF15810.5 GAM24939.1 - 0.0083 16.4 0.1 2.5e+02 1.9 0.0 5.6 1 1 7 8 8 8 0 Coiled-coil domain-containing protein 117 Romo1 PF10247.9 GAM24939.1 - 4.4 7.7 22.2 11 6.5 0.1 6.7 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ABC_tran PF00005.27 GAM24940.1 - 4.5e-41 140.6 0.0 1.2e-22 80.9 0.0 4.8 4 2 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 GAM24940.1 - 1.7e-17 63.2 5.4 1.7e-17 63.2 5.4 5.8 5 1 0 6 6 2 1 ABC transporter AAA_21 PF13304.6 GAM24940.1 - 1e-09 38.6 10.6 0.0035 17.2 0.4 5.2 4 1 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 GAM24940.1 - 4e-07 30.1 0.6 0.0016 18.5 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM24940.1 - 2.6e-06 27.9 0.0 0.01 16.2 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM24940.1 - 5.3e-06 26.4 6.0 0.0084 16.0 0.0 3.7 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 GAM24940.1 - 8.6e-06 26.1 0.1 0.3 11.4 0.0 3.6 3 0 0 3 3 3 2 AAA domain NB-ARC PF00931.22 GAM24940.1 - 4.4e-05 22.8 1.8 0.066 12.4 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain RNA_helicase PF00910.22 GAM24940.1 - 6e-05 23.4 0.3 0.38 11.1 0.0 3.7 4 0 0 4 4 3 2 RNA helicase AAA_29 PF13555.6 GAM24940.1 - 7e-05 22.5 4.1 0.037 13.8 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_33 PF13671.6 GAM24940.1 - 9.5e-05 22.6 0.0 0.82 9.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain SRP54 PF00448.22 GAM24940.1 - 0.00012 21.8 2.1 0.81 9.3 0.0 3.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain NACHT PF05729.12 GAM24940.1 - 0.00022 21.2 0.6 0.67 9.9 0.0 3.0 3 0 0 3 3 3 2 NACHT domain NTPase_1 PF03266.15 GAM24940.1 - 0.00045 20.2 0.0 0.6 10.0 0.0 2.8 2 0 0 2 2 2 2 NTPase AAA PF00004.29 GAM24940.1 - 0.00053 20.4 0.9 0.26 11.7 0.0 3.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAM24940.1 - 0.0022 18.3 0.0 1.6 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM24940.1 - 0.0057 17.2 6.4 0.008 16.7 0.0 3.8 4 1 0 4 4 2 1 AAA domain MeaB PF03308.16 GAM24940.1 - 0.0058 15.7 0.2 2.4 7.0 0.0 2.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 GAM24940.1 - 0.0065 16.0 0.4 1.9 8.0 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_14 PF13173.6 GAM24940.1 - 0.0074 16.3 0.0 1.9 8.5 0.0 3.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAM24940.1 - 0.0078 15.4 2.5 1.1 8.3 0.0 3.0 4 0 0 4 4 4 2 Protein of unknown function (DUF815) AAA_5 PF07728.14 GAM24940.1 - 0.07 13.1 0.4 7.8 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 GAM24940.1 - 0.1 12.7 0.0 0.1 12.7 0.0 4.6 4 1 0 4 4 3 0 Helicase HerA, central domain Roc PF08477.13 GAM24940.1 - 0.58 10.4 5.9 2 8.6 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase B12D PF06522.11 GAM24941.1 - 7.5e-08 32.1 0.0 8.3e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit EPL1 PF10513.9 GAM24942.1 - 9e-13 48.9 0.2 9e-13 48.9 0.2 5.4 3 2 0 3 3 3 1 Enhancer of polycomb-like DUF4477 PF14780.6 GAM24942.1 - 0.23 11.1 1.8 0.56 9.8 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) RIC1 PF07064.13 GAM24943.1 - 1.1e-63 215.1 0.0 1.9e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 GAM24943.1 - 0.00055 20.2 0.0 0.086 13.1 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain GATA PF00320.27 GAM24944.1 - 3.5e-13 48.9 6.6 5.6e-13 48.3 6.6 1.3 1 0 0 1 1 1 1 GATA zinc finger Calpain_III PF01067.22 GAM24945.1 - 7.7e-36 123.4 0.0 7.6e-14 52.2 0.0 3.4 3 0 0 3 3 3 3 Calpain large subunit, domain III C2 PF00168.30 GAM24945.1 - 1.7e-05 25.0 0.4 1.7e-05 25.0 0.4 2.4 3 0 0 3 3 3 1 C2 domain DUF1296 PF06972.11 GAM24946.1 - 3e-05 24.1 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) HBS1_N PF08938.10 GAM24946.1 - 0.01 16.1 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus CUE PF02845.16 GAM24946.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 CUE domain SIR2_2 PF13289.6 GAM24948.1 - 5.3e-26 91.4 0.0 1.3e-25 90.1 0.0 1.7 1 0 0 1 1 1 1 SIR2-like domain RhoGAP PF00620.27 GAM24949.1 - 2.3e-34 118.4 0.3 4.7e-34 117.4 0.3 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 GAM24949.1 - 6e-27 94.2 4.1 4.8e-20 72.0 0.1 3.2 3 1 1 4 4 4 2 PH domain F-box-like PF12937.7 GAM24949.1 - 3.3e-07 30.1 2.2 3.3e-07 30.1 2.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAM24949.1 - 2.7e-06 27.1 2.1 2.7e-06 27.1 2.1 2.1 2 0 0 2 2 2 1 F-box domain PH_8 PF15409.6 GAM24949.1 - 8.8e-06 25.9 3.5 0.036 14.3 0.1 3.2 3 1 0 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.6 GAM24949.1 - 6.5e-05 23.3 5.2 0.0028 18.0 0.3 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 GAM24949.1 - 0.00091 19.3 1.2 0.009 16.1 0.0 2.8 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 GAM24949.1 - 0.0027 18.1 1.1 2.3 8.6 0.1 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain RGS12_us2 PF16611.5 GAM24949.1 - 0.064 13.7 0.0 0.064 13.7 0.0 2.9 3 0 0 3 3 3 0 Unstructured region between RBD and GoLoco Ras PF00071.22 GAM24950.1 - 1.3e-59 200.4 0.1 1.5e-59 200.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24950.1 - 2.3e-33 115.0 0.1 4.1e-33 114.1 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24950.1 - 6.2e-13 48.6 0.0 8.2e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM24950.1 - 3e-05 24.1 0.1 7.7e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM24950.1 - 0.00017 21.2 0.1 0.0057 16.2 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM24950.1 - 0.00047 20.1 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GAM24950.1 - 0.00087 18.7 0.0 0.0014 18.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 GAM24950.1 - 0.0075 16.0 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 GAM24950.1 - 0.0076 15.7 0.0 0.021 14.3 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Septin PF00735.18 GAM24950.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin MIF4G PF02854.19 GAM24951.1 - 1e-06 28.5 0.2 1e-06 28.5 0.2 2.6 3 0 0 3 3 3 1 MIF4G domain Sec7_N PF12783.7 GAM24951.1 - 0.036 14.0 0.6 0.12 12.3 0.6 1.9 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Lant_dehydr_N PF04738.13 GAM24951.1 - 0.063 11.4 0.0 0.093 10.8 0.0 1.1 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus BAR_3 PF16746.5 GAM24952.1 - 0.00028 20.7 3.8 0.00042 20.1 3.8 1.2 1 0 0 1 1 1 1 BAR domain of APPL family TMF_TATA_bd PF12325.8 GAM24952.1 - 0.018 15.3 0.2 0.018 15.3 0.2 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RIH_assoc PF08454.11 GAM24952.1 - 0.026 14.3 1.2 0.048 13.5 0.5 1.8 2 0 0 2 2 2 0 RyR and IP3R Homology associated INTS5_N PF14837.6 GAM24952.1 - 0.035 13.7 0.4 0.067 12.8 0.1 1.6 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus SPATA1_C PF15743.5 GAM24952.1 - 0.053 13.6 0.6 0.053 13.6 0.6 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus PDE4_UCR PF18100.1 GAM24952.1 - 0.37 11.4 2.7 0.55 10.9 0.3 2.1 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) PhoLip_ATPase_C PF16212.5 GAM24953.1 - 2.1e-64 217.7 35.3 2.1e-64 217.7 35.3 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM24953.1 - 7e-23 80.1 0.5 2.6e-22 78.3 0.5 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 GAM24953.1 - 3.5e-11 42.9 3.5 2.3e-10 40.3 0.0 3.1 2 2 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM24953.1 - 5.4e-11 43.2 0.0 3.1e-05 24.4 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM24953.1 - 2.5e-10 40.3 0.0 7.7e-09 35.5 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM24953.1 - 0.0045 16.8 0.1 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase COX4 PF02936.14 GAM24953.1 - 0.087 12.9 0.1 0.26 11.3 0.1 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV FtsL PF04999.13 GAM24953.1 - 4 7.5 5.8 0.75 9.8 0.1 2.8 3 0 0 3 3 3 0 Cell division protein FtsL Adaptin_N PF01602.20 GAM24954.1 - 1.6e-78 264.5 0.5 1.6e-78 264.5 0.5 1.6 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 GAM24954.1 - 3.6e-25 88.9 0.3 1.2e-22 80.6 0.0 3.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 GAM24954.1 - 8.2e-14 51.6 0.1 2.1e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 GAM24954.1 - 3e-07 30.7 0.0 0.0042 17.4 0.0 3.7 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 GAM24954.1 - 6.4e-07 29.1 0.2 0.6 10.5 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat RTP1_C1 PF10363.9 GAM24954.1 - 0.00011 22.4 0.0 0.0052 16.9 0.0 3.5 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Diphthami_syn_2 PF01902.17 GAM24955.1 - 1.2e-21 77.2 0.0 5.6e-21 75.1 0.0 1.8 1 1 0 1 1 1 1 Diphthamide synthase DUF4325 PF14213.6 GAM24955.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) WD40 PF00400.32 GAM24956.1 - 9.5e-95 307.9 70.2 1.5e-09 38.3 0.4 21.1 21 0 0 21 21 20 17 WD domain, G-beta repeat TROVE PF05731.11 GAM24956.1 - 3.4e-83 280.1 1.0 6.3e-78 262.8 1.3 3.4 1 1 1 2 2 2 2 TROVE domain ANAPC4_WD40 PF12894.7 GAM24956.1 - 9.7e-35 118.8 11.9 3.9e-07 30.3 0.1 10.9 4 3 5 11 11 10 7 Anaphase-promoting complex subunit 4 WD40 domain DUF4062 PF13271.6 GAM24956.1 - 2.9e-19 69.2 0.6 4.4e-18 65.4 0.0 3.1 3 0 0 3 3 2 1 Domain of unknown function (DUF4062) eIF2A PF08662.11 GAM24956.1 - 4e-14 53.0 19.0 0.014 15.3 0.2 8.2 4 3 3 8 8 7 5 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM24956.1 - 2.5e-13 49.7 9.5 0.21 10.5 0.0 10.8 5 3 6 12 12 12 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAM24956.1 - 5.3e-13 49.0 6.1 0.00033 20.1 0.0 6.3 5 1 2 7 7 7 4 WD40-like domain Coatomer_WDAD PF04053.14 GAM24956.1 - 5e-07 29.1 14.9 0.0053 15.9 0.2 5.2 3 3 2 5 5 5 2 Coatomer WD associated region AAA_22 PF13401.6 GAM24956.1 - 1.1e-06 29.0 0.0 8.2e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAM24956.1 - 1.4e-06 28.3 0.0 3.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain APAF1_C PF17908.1 GAM24956.1 - 6.1e-06 26.3 0.1 0.00088 19.3 0.1 3.2 1 1 0 1 1 1 1 APAF-1 helical domain AAA_16 PF13191.6 GAM24956.1 - 2.8e-05 24.6 0.2 0.0034 17.8 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain PD40 PF07676.12 GAM24956.1 - 3.7e-05 23.5 8.3 0.065 13.2 0.0 7.2 10 0 0 10 10 7 1 WD40-like Beta Propeller Repeat ATPase_2 PF01637.18 GAM24956.1 - 9.8e-05 22.4 0.0 0.00027 20.9 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Roc PF08477.13 GAM24956.1 - 0.0077 16.5 0.3 11 6.2 0.0 4.0 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase Hira PF07569.11 GAM24956.1 - 0.01 15.6 0.7 1.6 8.4 0.2 3.5 2 0 0 2 2 2 0 TUP1-like enhancer of split DUF2075 PF09848.9 GAM24956.1 - 0.046 13.0 0.7 0.094 11.9 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF4080 PF13311.6 GAM24956.1 - 0.066 13.4 2.1 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) AAA_30 PF13604.6 GAM24956.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain BBS1 PF14779.6 GAM24956.1 - 0.094 12.1 0.0 3.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 ABC_tran PF00005.27 GAM24956.1 - 0.1 13.1 0.0 0.39 11.2 0.0 2.0 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 GAM24956.1 - 0.11 12.4 0.2 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase COE1_HLH PF16423.5 GAM24956.1 - 0.13 12.0 0.2 0.34 10.7 0.2 1.6 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain Zeta_toxin PF06414.12 GAM24956.1 - 0.16 11.2 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 GAM24956.1 - 0.17 12.2 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain TFIIIC_delta PF12657.7 GAM24956.1 - 0.22 11.4 4.9 32 4.4 0.0 4.7 4 1 0 4 4 3 0 Transcription factor IIIC subunit delta N-term FoP_duplication PF13865.6 GAM24956.1 - 1.9 9.1 11.0 3.8 8.1 11.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Shisa PF13908.6 GAM24957.1 - 0.22 11.8 0.6 0.38 11.0 0.6 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1275 PF06912.11 GAM24957.1 - 0.23 11.4 7.9 0.33 10.9 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Claudin_2 PF13903.6 GAM24957.1 - 4.4 7.0 11.1 0.17 11.6 0.7 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF5383 PF17355.2 GAM24958.1 - 1.1 9.6 3.4 1.5 9.2 3.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) DEAD PF00270.29 GAM24959.1 - 7.1e-47 159.4 0.0 4.6e-45 153.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM24959.1 - 5e-26 91.2 0.2 6.3e-25 87.7 0.2 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM24959.1 - 4.8e-08 33.2 0.0 1.9e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAM24959.1 - 0.00068 19.4 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase CMS1 PF14617.6 GAM24959.1 - 0.0068 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 GAM24959.1 - 0.043 12.6 0.0 4.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Methyltransf_11 PF08241.12 GAM24960.1 - 1.4e-15 57.7 0.1 2.1e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM24960.1 - 2.2e-11 44.3 0.2 8.5e-11 42.4 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM24960.1 - 5.9e-11 42.4 0.1 8.3e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM24960.1 - 1.4e-08 34.4 0.6 2.7e-07 30.2 0.6 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 GAM24960.1 - 4.1e-05 23.3 0.0 5.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 GAM24960.1 - 8.4e-05 23.3 0.0 0.00015 22.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 GAM24960.1 - 0.00061 19.5 0.0 0.00087 19.0 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Alpha_L_fucos PF01120.17 GAM24961.1 - 3e-114 382.1 4.1 3.8e-114 381.8 4.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 GAM24961.1 - 5.3e-14 52.5 0.0 1.2e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Kelch_1 PF01344.25 GAM24962.1 - 4.8e-53 176.5 7.8 3.9e-08 32.8 0.8 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAM24962.1 - 1.2e-47 159.4 6.1 2.5e-08 34.0 0.2 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM24962.1 - 4.6e-46 154.6 10.6 2.6e-08 33.7 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM24962.1 - 5.3e-42 140.3 12.1 5.2e-09 35.7 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAM24962.1 - 2.8e-39 132.1 13.9 8.5e-10 38.6 0.0 6.3 3 2 3 6 6 6 5 Kelch motif Kelch_5 PF13854.6 GAM24962.1 - 2.5e-37 126.3 5.2 6.6e-08 32.4 0.1 6.2 6 0 0 6 6 6 5 Kelch motif PQQ_3 PF13570.6 GAM24962.1 - 0.0027 18.2 9.5 0.34 11.5 0.2 6.0 3 1 3 6 6 6 1 PQQ-like domain DUF1668 PF07893.13 GAM24962.1 - 0.043 13.2 3.0 4.1 6.6 0.1 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1668) CLN5 PF15014.6 GAM24963.1 - 3e-36 125.6 11.9 4.6e-36 125.0 11.9 1.3 1 1 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 DUF1647 PF07801.11 GAM24963.1 - 0.046 13.5 1.1 0.076 12.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) Abhydrolase_1 PF00561.20 GAM24964.1 - 2.6e-13 50.2 0.0 3.1e-12 46.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM24964.1 - 2.3e-12 46.7 0.0 9.2e-12 44.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAM24964.1 - 3.1e-08 33.6 0.6 1.4e-07 31.5 0.1 2.2 3 0 0 3 3 3 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAM24964.1 - 3.7e-07 31.0 0.0 5e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 GAM24964.1 - 0.0019 18.1 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Ndr PF03096.14 GAM24964.1 - 0.0034 16.1 0.0 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 GAM24964.1 - 0.0039 17.1 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 GAM24964.1 - 0.0039 17.0 0.0 0.016 15.0 0.0 1.9 2 1 1 3 3 3 1 Alpha/beta hydrolase family BAAT_C PF08840.11 GAM24964.1 - 0.012 15.6 0.4 0.036 14.0 0.4 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.9 GAM24964.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.3 1 1 0 1 1 1 0 Abhydrolase domain containing 18 Chlorophyllase PF07224.11 GAM24964.1 - 0.023 13.7 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.20 GAM24964.1 - 0.025 14.2 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 GAM24964.1 - 0.03 13.2 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 GAM24964.1 - 0.033 13.7 0.1 0.059 12.9 0.1 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF1749 PF08538.10 GAM24964.1 - 0.076 12.1 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Thioesterase PF00975.20 GAM24964.1 - 0.078 13.1 0.0 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain ThiJ_like PF17124.5 GAM24964.1 - 0.092 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 ThiJ/PfpI family-like PQ-loop PF04193.14 GAM24966.1 - 3.8e-14 52.2 15.8 8.6e-11 41.5 5.6 4.4 4 1 1 5 5 5 2 PQ loop repeat Methyltransf_31 PF13847.6 GAM24967.1 - 1.3e-16 60.8 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM24967.1 - 1e-13 51.2 0.1 2.8e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 GAM24967.1 - 2.2e-10 41.1 0.0 3.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAM24967.1 - 3.5e-06 26.8 0.0 7.3e-06 25.7 0.0 1.5 1 1 1 2 2 2 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 GAM24967.1 - 4.8e-06 26.4 0.0 7.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 GAM24967.1 - 5.5e-06 26.3 0.0 8.7e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM24967.1 - 1.4e-05 25.7 0.0 4.3e-05 24.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 GAM24967.1 - 4.3e-05 23.1 0.0 0.00011 21.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 GAM24967.1 - 0.00017 21.4 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 GAM24967.1 - 0.0003 21.4 0.0 0.00055 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 GAM24967.1 - 0.0007 19.0 0.0 0.00097 18.5 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_18 PF12847.7 GAM24967.1 - 0.0042 17.0 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAM24967.1 - 0.0061 16.6 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 GAM24967.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 GAM24967.1 - 0.029 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_10 PF05971.12 GAM24967.1 - 0.044 13.1 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase DOT1 PF08123.13 GAM24967.1 - 0.047 13.2 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_3 PF01596.17 GAM24967.1 - 0.047 12.9 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Ubie_methyltran PF01209.18 GAM24967.1 - 0.071 12.4 0.0 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 GAM24967.1 - 0.097 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TehB PF03848.14 GAM24967.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 GAM24967.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4164 PF13747.6 GAM24968.1 - 0.0055 17.0 2.2 0.0055 17.0 2.2 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4164) MukF_M PF17192.4 GAM24968.1 - 0.0078 16.0 1.4 0.0078 16.0 1.4 2.0 1 1 0 2 2 2 1 MukF middle domain UPF0242 PF06785.11 GAM24968.1 - 0.0095 16.1 13.6 0.015 15.4 13.6 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus IFT57 PF10498.9 GAM24968.1 - 0.091 11.7 15.8 0.053 12.5 11.2 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF5082 PF16888.5 GAM24968.1 - 0.16 12.3 12.2 1.5 9.1 3.1 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Exonuc_VII_L PF02601.15 GAM24968.1 - 0.4 10.2 9.3 0.57 9.7 9.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 GAM24968.1 - 0.56 10.3 10.6 0.04 14.0 4.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 GAM24968.1 - 0.76 10.1 26.4 2.5 8.4 11.7 2.7 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF3552 PF12072.8 GAM24968.1 - 0.82 9.1 21.4 0.26 10.7 8.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ABC_tran_CTD PF16326.5 GAM24968.1 - 0.88 9.9 16.4 7.5 6.9 3.3 3.9 2 1 2 4 4 4 0 ABC transporter C-terminal domain FliD_C PF07195.12 GAM24968.1 - 0.95 8.8 7.8 1.8 7.9 1.1 2.6 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus MDH PF02315.16 GAM24968.1 - 0.97 9.5 10.2 0.37 10.9 1.2 2.7 2 1 0 2 2 2 0 Methanol dehydrogenase beta subunit DUF5595 PF18077.1 GAM24968.1 - 3.5 7.8 12.2 0.3 11.2 0.3 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) DUF4094 PF13334.6 GAM24968.1 - 3.7 8.0 6.9 0.48 10.9 1.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Fib_alpha PF08702.10 GAM24968.1 - 7 6.8 18.8 0.038 14.2 9.6 2.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 GAM24968.1 - 9.8 6.7 17.3 22 5.6 4.6 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 DuoxA PF10204.9 GAM24969.1 - 8.3 5.3 18.4 9 5.2 18.4 1.0 1 0 0 1 1 1 0 Dual oxidase maturation factor Lactamase_B_2 PF12706.7 GAM24970.1 - 3.5e-33 114.8 0.0 6.1e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM24970.1 - 2e-14 53.8 0.0 2.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rep_fac_C PF08542.11 GAM24971.1 - 6.7e-24 84.1 0.0 2.3e-23 82.4 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 GAM24971.1 - 2.4e-13 50.2 0.0 8.4e-10 38.7 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 GAM24971.1 - 4e-13 49.9 0.0 8.5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAM24971.1 - 5.7e-07 29.6 0.0 1.8e-06 28.0 0.0 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 GAM24971.1 - 7.7e-07 29.6 0.0 0.00012 22.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 GAM24971.1 - 1.2e-06 28.6 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM24971.1 - 1.7e-06 28.4 0.1 0.0085 16.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.6 GAM24971.1 - 0.00011 22.1 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAM24971.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 GAM24971.1 - 0.0007 19.6 0.0 0.0018 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAM24971.1 - 0.0013 18.2 0.0 0.01 15.2 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAM24971.1 - 0.0014 19.1 0.0 0.0029 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM24971.1 - 0.0016 18.8 0.1 0.0096 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAM24971.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 GAM24971.1 - 0.002 18.1 0.0 0.063 13.2 0.0 2.3 2 0 0 2 2 2 1 NTPase RuvB_N PF05496.12 GAM24971.1 - 0.0034 17.2 0.0 0.0092 15.7 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 GAM24971.1 - 0.0034 17.1 0.0 0.012 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAM24971.1 - 0.0054 16.3 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 GAM24971.1 - 0.0061 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 GAM24971.1 - 0.0061 16.3 0.1 0.37 10.6 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase Arm_vescicular PF18770.1 GAM24971.1 - 0.0073 16.2 0.1 1.5 8.8 0.0 2.7 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor RNA_helicase PF00910.22 GAM24971.1 - 0.01 16.2 0.0 0.077 13.4 0.0 2.1 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 GAM24971.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_assoc_2 PF16193.5 GAM24971.1 - 0.016 15.5 0.0 0.058 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain TniB PF05621.11 GAM24971.1 - 0.018 14.5 0.0 6.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein T2SSE PF00437.20 GAM24971.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 GAM24971.1 - 0.026 14.5 0.0 5.8 6.9 0.0 2.7 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit MCM PF00493.23 GAM24971.1 - 0.039 13.0 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain DNA_pol3_delta PF06144.13 GAM24971.1 - 0.045 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_3 PF07726.11 GAM24971.1 - 0.051 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 GAM24971.1 - 0.051 14.1 0.1 0.081 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAM24971.1 - 0.057 12.6 0.1 0.57 9.4 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 GAM24971.1 - 0.059 12.9 0.1 0.17 11.4 0.1 1.8 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAM24971.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 GAM24971.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.23 GAM24971.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 GAM24971.1 - 0.12 12.8 0.0 0.38 11.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 GAM24971.1 - 0.16 12.1 0.1 0.6 10.3 0.0 1.9 1 1 0 2 2 2 0 AAA domain DUF4883 PF16224.5 GAM24972.1 - 0.0043 17.3 1.3 0.0046 17.2 1.3 1.1 1 0 0 1 1 1 1 DOmain of unknown function (DUF4883) CDC73_N PF16050.5 GAM24972.1 - 0.0083 15.5 0.1 0.0083 15.5 0.1 1.1 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal Closter_coat PF01785.17 GAM24972.1 - 0.033 13.5 0.5 0.034 13.4 0.5 1.0 1 0 0 1 1 1 0 Closterovirus coat protein DUF3215 PF11503.8 GAM24972.1 - 0.083 12.8 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3215) Nramp PF01566.18 GAM24973.1 - 1.4e-136 455.2 23.7 1.4e-136 455.2 23.7 2.0 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Phage_holin_Dp1 PF16938.5 GAM24973.1 - 4.7 7.5 11.4 3.3 8.0 1.5 3.6 3 0 0 3 3 3 0 Putative phage holin Dp-1 FNIP PF05725.12 GAM24974.1 - 1.6e-44 149.8 27.4 1.3e-17 63.7 0.5 6.1 4 2 3 7 7 7 5 FNIP Repeat FNIP PF05725.12 GAM24975.1 - 2.8e-74 245.0 32.0 2.1e-14 53.4 0.0 9.0 7 2 1 9 9 9 8 FNIP Repeat LRR_5 PF13306.6 GAM24975.1 - 1e-06 28.7 1.0 0.003 17.5 0.0 3.7 1 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) Nbl1_Borealin_N PF10444.9 GAM24975.1 - 0.0031 17.1 0.0 0.94 9.2 0.0 3.9 5 0 0 5 5 5 1 Nbl1 / Borealin N terminal LRR_4 PF12799.7 GAM24975.1 - 0.16 12.5 11.6 0.15 12.5 1.0 4.5 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) RNA_pol_Rpb1_1 PF04997.12 GAM24976.1 - 1.2e-90 304.1 2.2 1.9e-90 303.4 2.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GAM24976.1 - 1.1e-88 297.2 0.9 1.6e-88 296.6 0.9 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAM24976.1 - 3.8e-75 251.7 0.0 8.1e-75 250.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GAM24976.1 - 1.6e-36 125.6 0.0 4.5e-35 120.9 0.0 3.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAM24976.1 - 1e-32 112.3 0.1 8.3e-32 109.3 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Ala_racemase_C PF00842.21 GAM24978.1 - 0.09 12.6 0.4 0.26 11.1 0.3 1.8 1 1 0 1 1 1 0 Alanine racemase, C-terminal domain Mucin PF01456.17 GAM24978.1 - 0.89 9.5 31.3 2.3 8.2 31.3 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Plasmodium_Vir PF05795.11 GAM24978.1 - 3.3 7.0 7.1 6.1 6.2 7.1 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RIFIN PF02009.16 GAM24978.1 - 4.1 7.2 6.5 5.7 6.7 6.5 1.2 1 0 0 1 1 1 0 Rifin Response_reg PF00072.24 GAM24979.1 - 1.3e-21 76.9 0.0 2.7e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GAM24980.1 - 1.5e-27 96.3 0.1 3.2e-27 95.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAM24980.1 - 1.6e-14 53.7 0.0 4.7e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 GAM24980.1 - 1.3e-06 28.3 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 GAM24980.1 - 0.0013 19.0 0.0 0.0045 17.2 0.0 2.0 2 0 0 2 2 2 1 PAS domain HATPase_c_3 PF13589.6 GAM24980.1 - 0.05 13.4 0.2 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MctB PF11382.8 GAM24980.1 - 0.16 11.6 0.8 0.24 11.1 0.1 1.5 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB CRAL_TRIO_2 PF13716.6 GAM24981.1 - 3.4e-43 147.1 0.5 8.3e-43 145.9 0.3 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GAM24981.1 - 1e-06 28.6 1.5 1.3e-06 28.2 0.5 1.8 1 1 1 2 2 2 1 CRAL/TRIO domain DSPc PF00782.20 GAM24982.1 - 9.5e-32 109.6 0.1 9.5e-32 109.6 0.1 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM24982.1 - 0.00027 20.6 0.0 0.00027 20.6 0.0 1.9 1 1 1 2 2 2 1 Protein-tyrosine phosphatase LssY_C PF14067.6 GAM24983.1 - 0.07 12.7 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 LssY C-terminus Rad52_Rad22 PF04098.15 GAM24984.1 - 2.5e-44 150.9 0.0 4e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RNase_PH PF01138.21 GAM24985.1 - 2.4e-24 86.3 0.7 6.5e-24 84.9 0.4 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAM24985.1 - 0.041 13.9 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Met_10 PF02475.16 GAM24985.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Ras PF00071.22 GAM24986.1 - 2.1e-44 150.9 0.1 2.6e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM24986.1 - 1.5e-28 99.4 0.0 2.1e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM24986.1 - 3.2e-09 36.5 0.1 4e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM24986.1 - 1.4e-06 27.8 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 GAM24986.1 - 0.00031 20.5 0.0 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 GAM24986.1 - 0.0014 18.7 0.0 0.0021 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 GAM24986.1 - 0.0024 17.3 0.1 0.055 12.9 0.1 2.3 2 1 1 3 3 3 1 Bacterial TniB protein GTP_EFTU PF00009.27 GAM24986.1 - 0.0026 17.3 0.3 0.31 10.6 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 GAM24986.1 - 0.0029 17.2 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 GAM24986.1 - 0.0087 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 GAM24986.1 - 0.024 14.4 0.0 0.76 9.5 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 GAM24986.1 - 0.039 14.0 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4998 PF16389.5 GAM24986.1 - 0.056 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function AAA_16 PF13191.6 GAM24986.1 - 0.061 13.7 0.1 0.088 13.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 GAM24986.1 - 0.066 12.4 0.0 7.2 5.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 GAM24986.1 - 0.07 12.9 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 GAM24986.1 - 0.12 11.2 0.0 3.4 6.4 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA PF00004.29 GAM24986.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM24986.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.26 GAM24987.1 - 1.6e-28 99.1 0.3 3e-27 95.0 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme LRR_4 PF12799.7 GAM24987.1 - 1.4e-08 34.9 22.0 0.0053 17.2 0.0 8.7 4 3 6 10 10 10 5 Leucine Rich repeats (2 copies) zf-CCCH_4 PF18044.1 GAM24987.1 - 5.4e-06 26.1 2.8 2.1e-05 24.2 2.8 2.1 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 GAM24987.1 - 0.00018 22.2 0.2 0.00051 20.7 0.2 1.7 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 GAM24987.1 - 0.00021 21.2 5.0 0.00021 21.2 5.0 2.5 2 0 0 2 2 2 1 Zinc finger domain LRR_6 PF13516.6 GAM24987.1 - 0.00066 19.5 23.1 5.7 7.3 0.1 10.2 11 0 0 11 11 11 1 Leucine Rich repeat zf-CCCH PF00642.24 GAM24987.1 - 0.00096 19.0 1.5 0.0034 17.2 1.5 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_1 PF00560.33 GAM24987.1 - 0.03 14.8 22.9 5.6 7.9 0.1 10.0 10 1 0 10 10 10 0 Leucine Rich Repeat Prok-E2_B PF14461.6 GAM24987.1 - 0.091 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B TPR_17 PF13431.6 GAM24987.1 - 0.18 12.2 3.5 3.2 8.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat CLU PF13236.6 GAM24988.1 - 4.3e-58 196.8 0.0 1.1e-57 195.4 0.0 1.7 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 GAM24988.1 - 1.4e-12 48.0 0.1 1.4e-12 48.0 0.1 3.2 3 1 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 CLASP_N PF12348.8 GAM24989.1 - 9.8e-23 80.9 20.4 8.7e-08 32.0 0.4 6.4 6 0 0 6 6 6 4 CLASP N terminal HEAT PF02985.22 GAM24989.1 - 1.9e-13 49.4 7.7 0.42 11.0 0.0 9.7 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.6 GAM24989.1 - 5.6e-09 36.3 3.4 0.16 12.5 0.0 6.2 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 GAM24989.1 - 6.9e-08 32.8 5.3 9.2 6.7 0.0 9.0 8 2 2 10 10 10 1 HEAT repeats Cnd1 PF12717.7 GAM24989.1 - 8e-07 29.2 23.9 0.071 13.1 0.1 9.5 7 3 4 11 11 11 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GAM24989.1 - 4.1e-06 27.3 0.3 2.6 8.7 0.0 7.2 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 GAM24989.1 - 0.088 12.3 5.7 4.1 6.9 0.0 4.9 5 0 0 5 5 5 0 Tti2 family NUC173 PF08161.12 GAM24989.1 - 2.9 7.5 9.9 6.8 6.3 0.1 5.5 6 2 2 8 8 8 0 NUC173 domain VIT PF08487.10 GAM24990.1 - 2.9e-41 140.1 0.0 7.6e-41 138.8 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain PARP PF00644.20 GAM24990.1 - 2.4e-26 92.5 1.1 1.5e-25 90.0 1.1 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain VWA_3 PF13768.6 GAM24990.1 - 9.5e-22 77.6 0.0 2.9e-21 76.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain 14-3-3 PF00244.20 GAM24990.1 - 1.5e-20 73.7 3.0 1.5e-20 73.7 3.0 2.4 2 0 0 2 2 2 1 14-3-3 protein VWA PF00092.28 GAM24990.1 - 1.4e-14 54.7 0.0 5e-14 52.9 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 GAM24990.1 - 6e-12 45.3 0.0 1.4e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 GAM24990.1 - 6.5e-10 39.6 0.0 6.2e-09 36.5 0.0 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Ribosomal_60s PF00428.19 GAM24990.1 - 7.6e-07 29.6 13.9 0.0019 18.8 5.2 5.5 5 0 0 5 5 5 2 60s Acidic ribosomal protein BRCT PF00533.26 GAM24990.1 - 1.4e-05 25.4 0.0 3.9e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain I_LWEQ PF01608.17 GAM24990.1 - 2.2e-05 24.8 2.9 0.00013 22.2 2.9 2.5 1 0 0 1 1 1 1 I/LWEQ domain TPR_12 PF13424.6 GAM24990.1 - 9.9e-05 22.6 1.2 0.0092 16.3 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat BRCT_2 PF16589.5 GAM24990.1 - 0.00074 19.9 2.4 0.0017 18.7 0.5 2.6 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain vWA-TerF-like PF10138.9 GAM24990.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF5595 PF18077.1 GAM24990.1 - 0.12 12.5 0.1 0.39 10.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) Thg1 PF04446.12 GAM24991.1 - 1.9e-32 111.9 0.1 3.2e-32 111.2 0.1 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 GAM24991.1 - 0.0073 16.5 0.1 0.02 15.1 0.1 1.8 1 1 0 1 1 1 1 Thg1 C terminal domain Acetyltransf_3 PF13302.7 GAM24992.1 - 9.1e-18 65.3 0.0 1.7e-17 64.4 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM24992.1 - 0.0012 19.0 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ig_5 PF16681.5 GAM24992.1 - 0.068 13.6 0.7 0.16 12.4 0.1 1.9 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Myotub-related PF06602.14 GAM24993.1 - 1.1e-93 313.9 12.8 1.3e-63 215.1 0.8 3.1 2 1 1 3 3 3 2 Myotubularin-like phosphatase domain GRAM PF02893.20 GAM24993.1 - 0.0086 15.9 0.0 0.023 14.6 0.0 1.8 1 1 0 1 1 1 1 GRAM domain AP3D1 PF06375.11 GAM24993.1 - 0.0096 16.2 4.3 0.0096 16.2 4.3 2.5 2 0 0 2 2 2 1 AP-3 complex subunit delta-1 MtrB PF05440.12 GAM24993.1 - 7.3 7.1 5.4 5.3 7.5 0.3 2.8 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Glyco_transf_20 PF00982.21 GAM24994.1 - 1.9e-116 389.6 0.0 2.7e-116 389.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAM24994.1 - 1.1e-31 109.8 0.0 1.7e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Rad60-SLD PF11976.8 GAM24995.1 - 1.6e-26 92.0 1.6 5.2e-15 55.0 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAM24995.1 - 0.0004 20.1 1.6 0.016 15.0 0.1 3.3 3 0 0 3 3 3 2 Ubiquitin family CYTH PF01928.21 GAM24995.1 - 0.018 15.0 0.1 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 CYTH domain TUG-UBL1 PF11470.8 GAM24995.1 - 0.033 14.4 0.1 2.5 8.4 0.0 2.7 2 0 0 2 2 2 0 TUG ubiquitin-like domain AT_hook PF02178.19 GAM24995.1 - 0.29 11.1 4.3 0.62 10.1 4.3 1.6 1 0 0 1 1 1 0 AT hook motif RE_HpaII PF09561.10 GAM24995.1 - 0.36 10.1 5.5 0.56 9.5 5.5 1.3 1 0 0 1 1 1 0 HpaII restriction endonuclease MFS_1 PF07690.16 GAM24996.1 - 1.2e-38 132.9 32.7 2.8e-28 98.9 20.9 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 GAM24996.1 - 3e-18 65.6 14.2 3e-18 65.6 14.2 1.9 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.24 GAM24996.1 - 5.7e-13 48.5 23.4 1.5e-06 27.4 0.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 GAM24996.1 - 0.028 12.8 7.0 0.6 8.4 4.9 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF4674 PF15719.5 GAM24996.1 - 3.1 7.8 6.1 4.7 7.2 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) MFS_2 PF13347.6 GAM24997.1 - 3.2e-96 322.5 30.8 3.8e-96 322.3 30.8 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 GAM24997.1 - 1.1e-17 64.0 28.8 1.1e-17 64.0 28.8 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily AATase PF07247.12 GAM24998.1 - 0.00061 18.5 0.0 0.00079 18.1 0.0 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase zf-C3H1 PF10650.9 GAM24999.1 - 3.1e-08 33.2 0.4 5.8e-08 32.3 0.4 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain PH_18 PF18469.1 GAM24999.1 - 0.018 15.0 0.1 0.069 13.1 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain TPR_19 PF14559.6 GAM24999.1 - 0.066 13.7 0.0 2.9 8.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MADF_DNA_bdg PF10545.9 GAM24999.1 - 0.12 12.7 0.5 2.9 8.3 0.0 2.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Occludin_ELL PF07303.13 GAM24999.1 - 0.13 13.0 2.4 0.3 11.8 0.5 2.7 2 0 0 2 2 2 0 Occludin homology domain DUF489 PF04356.12 GAM24999.1 - 0.14 12.2 3.5 0.43 10.5 3.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF489) zf-CCCH PF00642.24 GAM24999.1 - 0.19 11.7 0.3 0.31 11.0 0.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_17 PF13431.6 GAM24999.1 - 1.2 9.7 3.6 4.9 7.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.10 GAM24999.1 - 3.6 6.6 15.2 0.21 10.7 0.1 4.8 5 1 1 6 6 6 0 NRDE-2, necessary for RNA interference Pkinase_Tyr PF07714.17 GAM25000.1 - 2.7e-43 148.1 0.0 4.4e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM25000.1 - 3.2e-41 141.4 0.0 5.6e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAM25000.1 - 0.00021 21.3 0.0 0.00063 19.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM25000.1 - 0.00029 19.7 0.2 0.00071 18.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAM25000.1 - 0.00032 20.1 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM25000.1 - 0.048 13.0 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 GAM25000.1 - 0.052 13.2 0.0 0.052 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 CPSF73-100_C PF11718.8 GAM25000.1 - 0.077 12.5 1.8 0.16 11.5 1.8 1.5 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term PHD PF00628.29 GAM25001.1 - 7.9e-12 44.9 11.5 2.5e-11 43.3 11.5 2.0 1 0 0 1 1 1 1 PHD-finger Syntaxin-6_N PF09177.11 GAM25001.1 - 0.035 14.7 1.5 0.035 14.7 1.5 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Ipi1_N PF12333.8 GAM25002.1 - 1.4e-14 54.5 1.9 1.4e-14 54.5 1.9 3.8 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.7 GAM25002.1 - 0.046 14.3 0.0 0.52 11.0 0.1 2.7 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF1204 PF06721.11 GAM25002.1 - 0.28 10.6 7.6 0.65 9.4 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1204) Actin PF00022.19 GAM25003.1 - 5.3e-87 292.1 0.0 4.1e-56 190.3 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 GAM25003.1 - 0.094 11.5 0.0 6.1 5.6 0.0 2.3 2 1 0 2 2 2 0 MreB/Mbl protein PH_3 PF14593.6 GAM25003.1 - 0.14 12.3 0.3 12 6.1 0.0 2.3 2 0 0 2 2 2 0 PH domain adh_short PF00106.25 GAM25004.1 - 1.4e-47 161.7 0.1 2e-47 161.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM25004.1 - 1.6e-27 96.6 0.0 2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM25004.1 - 9.1e-10 38.7 0.7 5.2e-09 36.3 0.1 2.0 1 1 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 GAM25004.1 - 0.00062 19.1 0.6 0.0027 17.0 0.1 2.2 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 GAM25004.1 - 0.0016 18.4 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 GAM25004.1 - 0.0056 16.3 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 GAM25004.1 - 0.014 14.9 0.1 0.038 13.4 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.23 GAM25004.1 - 0.039 13.9 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 GAM25004.1 - 0.078 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DFP PF04127.15 GAM25004.1 - 0.13 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RhoGAP PF00620.27 GAM25005.1 - 1.1e-22 80.5 1.5 6.9e-22 77.9 0.0 2.7 3 1 0 3 3 3 1 RhoGAP domain FCH PF00611.23 GAM25005.1 - 5e-11 42.7 0.7 5e-11 42.7 0.7 2.6 3 0 0 3 3 2 1 Fes/CIP4, and EFC/F-BAR homology domain BRE1 PF08647.11 GAM25005.1 - 0.00038 20.5 4.0 0.00038 20.5 4.0 2.9 2 1 1 3 3 3 1 BRE1 E3 ubiquitin ligase Tektin PF03148.14 GAM25005.1 - 0.00061 18.6 6.4 0.001 17.9 5.6 1.8 1 1 1 2 2 2 1 Tektin family Filament PF00038.21 GAM25005.1 - 0.0014 18.2 4.3 0.0014 18.2 4.3 1.6 2 0 0 2 2 2 1 Intermediate filament protein Tup_N PF08581.10 GAM25005.1 - 0.023 15.0 2.2 0.023 15.0 2.2 2.4 1 1 1 2 2 2 0 Tup N-terminal DUF3439 PF11921.8 GAM25005.1 - 0.028 14.4 6.2 0.088 12.8 6.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3450 PF11932.8 GAM25005.1 - 0.055 12.8 2.9 0.11 11.8 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Dynein_heavy PF03028.15 GAM25005.1 - 0.058 13.5 0.0 27 4.9 0.0 3.3 3 0 0 3 3 3 0 Dynein heavy chain region D6 P-loop domain DUF4407 PF14362.6 GAM25005.1 - 0.12 11.8 1.0 0.2 11.0 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 GAM25005.1 - 0.29 11.8 7.3 0.12 13.0 3.9 2.1 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YtxH PF12732.7 GAM25005.1 - 1.3 9.6 7.1 22 5.6 4.5 2.8 2 0 0 2 2 2 0 YtxH-like protein ZapD PF07072.11 GAM25005.1 - 2.5 7.8 5.3 5.5 6.7 2.3 2.5 2 0 0 2 2 2 0 Cell division protein FemAB PF02388.16 GAM25005.1 - 2.6 6.8 8.7 1.3 7.9 2.9 2.2 1 1 1 2 2 2 0 FemAB family DUF1043 PF06295.12 GAM25005.1 - 4.3 7.4 7.2 11 6.1 0.5 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) TPR_MLP1_2 PF07926.12 GAM25005.1 - 5.5 7.1 17.9 0.31 11.1 2.4 2.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 GAM25005.1 - 7.8 7.0 15.2 1.6 9.2 10.1 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region FNIP PF05725.12 GAM25006.1 - 1.3e-39 134.0 0.2 9.2e-11 41.7 0.0 7.9 8 1 1 9 9 9 5 FNIP Repeat LRR_5 PF13306.6 GAM25006.1 - 0.054 13.5 0.6 1.4 8.9 0.0 3.2 3 1 1 4 4 4 0 BspA type Leucine rich repeat region (6 copies) MHC_II_beta PF00969.19 GAM25006.1 - 0.088 12.9 0.8 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain SLD5_C PF16922.5 GAM25007.1 - 3.5e-11 43.1 0.0 6.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 GAM25007.1 - 0.00025 21.5 0.2 0.00037 20.9 0.2 1.5 1 0 0 1 1 1 1 GINS complex protein EspA PF03433.13 GAM25007.1 - 0.049 13.5 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 EspA-like secreted protein RCC1 PF00415.18 GAM25008.1 - 2.9e-63 210.3 8.5 2.1e-12 47.5 0.1 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM25008.1 - 1.4e-39 133.1 27.2 2.7e-09 36.6 0.1 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 GAM25008.1 - 5.9e-23 81.2 0.1 9.4e-16 58.0 0.1 2.9 2 1 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.7 GAM25008.1 - 4.3e-07 30.4 0.2 1.1e-05 25.9 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM25008.1 - 3.2e-05 24.1 0.1 0.00015 21.9 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM25008.1 - 0.0077 16.8 0.0 0.045 14.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM25008.1 - 0.011 16.2 0.0 0.12 13.0 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat SWC7 PF17330.2 GAM25008.1 - 0.018 15.1 0.0 0.067 13.3 0.0 2.0 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Ank PF00023.30 GAM25008.1 - 0.025 15.0 0.1 0.096 13.2 0.1 2.1 1 0 0 1 1 1 0 Ankyrin repeat HSF_DNA-bind PF00447.17 GAM25010.1 - 4.6e-26 91.3 0.7 4.6e-26 91.3 0.7 3.2 3 1 0 3 3 3 1 HSF-type DNA-binding ZapB PF06005.12 GAM25010.1 - 0.0093 16.4 1.6 0.0093 16.4 1.6 4.6 3 1 0 3 3 3 1 Cell division protein ZapB Plavaka PF18759.1 GAM25011.1 - 0.00058 19.2 0.9 0.0012 18.2 0.3 1.9 2 1 0 2 2 2 1 Plavaka transposase FNIP PF05725.12 GAM25012.1 - 8.5e-62 205.1 20.0 1.7e-11 44.1 0.3 7.1 5 1 2 8 8 8 7 FNIP Repeat PDZ_3 PF17815.1 GAM25013.1 - 1.5e-40 138.4 0.1 2.3e-40 137.8 0.1 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 GAM25013.1 - 9.4e-23 81.8 0.1 1.9e-22 80.7 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 GAM25013.1 - 7.8e-18 65.1 0.0 2e-17 63.8 0.0 1.7 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 GAM25013.1 - 5.7e-12 45.8 1.3 5.4e-10 39.5 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 GAM25013.1 - 3.6e-06 26.7 0.9 0.00039 20.2 0.4 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 GAM25013.1 - 0.0008 19.7 2.4 0.016 15.5 0.2 2.6 2 0 0 2 2 2 1 PDZ domain PDZ_1 PF12812.7 GAM25013.1 - 0.032 14.3 0.3 2.4 8.2 0.0 3.2 3 0 0 3 3 3 0 PDZ-like domain BORCS7 PF16088.5 GAM25014.1 - 1.5e-25 89.4 4.4 1.9e-25 89.1 4.4 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 DUF1160 PF06648.11 GAM25014.1 - 0.013 15.5 1.1 0.015 15.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) HTH_ParB PF17762.1 GAM25014.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 HTH domain found in ParB protein SRPRB PF09439.10 GAM25014.1 - 0.033 13.6 1.1 0.039 13.4 1.1 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF948 PF06103.11 GAM25014.1 - 0.13 12.6 1.8 0.37 11.1 1.8 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SNF2_N PF00176.23 GAM25015.1 - 2.3e-74 250.2 0.5 3.7e-74 249.5 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAM25015.1 - 8.7e-38 128.9 8.8 8.7e-38 128.9 6.0 2.7 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.31 GAM25015.1 - 2.6e-18 66.4 0.9 1.2e-17 64.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HAND PF09110.11 GAM25015.1 - 3.3e-11 43.9 11.2 3.3e-11 43.9 11.2 5.8 4 2 0 4 4 4 1 HAND ResIII PF04851.15 GAM25015.1 - 1.5e-09 38.1 5.0 3.5e-09 36.9 0.0 3.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GAM25015.1 - 2.8e-08 33.3 0.0 2.8e-08 33.3 0.0 3.3 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 GAM25015.1 - 7.9e-06 25.8 0.0 5.2e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase DBINO PF13892.6 GAM25015.1 - 6.2e-05 23.4 12.2 6.2e-05 23.4 12.2 4.5 3 1 2 5 5 5 1 DNA-binding domain UDPGP PF01704.18 GAM25016.1 - 3.1e-48 164.5 0.0 4e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 GAM25016.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain adh_short PF00106.25 GAM25017.1 - 5.6e-48 163.0 0.3 8e-48 162.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM25017.1 - 1.5e-35 122.9 0.1 2.1e-35 122.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM25017.1 - 5.1e-11 42.8 0.1 8.1e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM25017.1 - 1.7e-05 24.3 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 GAM25017.1 - 0.00011 21.4 0.2 0.00027 20.1 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 GAM25017.1 - 0.00034 20.2 0.1 0.00063 19.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 GAM25017.1 - 0.025 14.5 0.1 0.095 12.7 0.1 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 GAM25017.1 - 0.11 11.8 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NUDIX PF00293.28 GAM25018.1 - 1.2e-20 73.9 0.2 1.7e-20 73.4 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain Shisa PF13908.6 GAM25019.1 - 0.011 16.0 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MHYT PF03707.16 GAM25019.1 - 0.12 12.5 3.2 8.9 6.6 1.3 2.3 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat ABC2_membrane_2 PF12679.7 GAM25019.1 - 0.57 9.4 5.9 0.82 8.9 5.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Bromodomain PF00439.25 GAM25020.1 - 3.3e-16 59.1 0.0 6.8e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 GAM25020.1 - 9.3e-10 38.8 0.1 1.7e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM25020.1 - 4.5e-05 23.4 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM25020.1 - 0.00027 21.3 0.3 0.00061 20.2 0.3 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RabGAP-TBC PF00566.18 GAM25021.1 - 5.4e-35 121.0 0.1 8.1e-35 120.4 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LMBR1 PF04791.16 GAM25022.1 - 9.6 5.0 5.7 10 4.9 5.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UQ_con PF00179.26 GAM25023.1 - 1.2e-19 70.3 0.0 2.4e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.18 GAM25023.1 - 0.0038 16.5 0.2 0.0064 15.8 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others MscS_TM PF12794.7 GAM25023.1 - 0.06 12.2 0.1 0.096 11.5 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RWD PF05773.22 GAM25023.1 - 0.09 13.1 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 RWD domain RIFIN PF02009.16 GAM25023.1 - 0.21 11.4 5.9 0.52 10.1 5.8 1.6 1 1 0 1 1 1 0 Rifin FAM196 PF15265.6 GAM25023.1 - 1.5 8.3 13.1 2 7.8 13.1 1.1 1 0 0 1 1 1 0 FAM196 family DUF2547 PF10818.8 GAM25023.1 - 2.3 9.2 6.9 6.1 7.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Suf PF05843.14 GAM25023.1 - 6.5 6.7 8.2 9.5 6.1 8.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SPX PF03105.19 GAM25023.1 - 6.8 6.5 11.7 11 5.8 11.7 1.3 1 0 0 1 1 1 0 SPX domain DUF3439 PF11921.8 GAM25023.1 - 8 6.4 25.5 1.7 8.7 8.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) LRR_9 PF14580.6 GAM25024.1 - 1.7e-14 53.7 1.9 4e-14 52.5 1.9 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 GAM25024.1 - 2.3e-12 46.9 26.0 1e-05 25.8 3.3 3.2 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM25024.1 - 2e-08 33.9 12.4 4.2e-06 26.4 5.6 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 GAM25024.1 - 0.0015 18.5 4.7 3.7 7.8 0.1 4.3 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 GAM25024.1 - 0.0097 16.3 12.8 2.9 8.8 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich Repeat DUF3439 PF11921.8 GAM25024.1 - 0.019 14.9 3.0 0.035 14.1 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAM25024.1 - 0.048 13.6 13.4 0.077 13.0 13.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.9 GAM25024.1 - 2.7 6.4 16.9 3.3 6.1 16.9 1.2 1 0 0 1 1 1 0 Macoilin family Med3 PF11593.8 GAM25024.1 - 2.9 7.0 8.3 4.7 6.3 8.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MGC-24 PF05283.11 GAM25024.1 - 3.7 8.0 9.4 6.4 7.2 9.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin BAT2_N PF07001.11 GAM25024.1 - 8 6.9 17.2 14 6.0 17.2 1.3 1 0 0 1 1 1 0 BAT2 N-terminus Ribosomal_L37ae PF01780.19 GAM25025.1 - 2.8e-41 139.5 8.6 3.1e-41 139.3 8.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 GAM25025.1 - 0.0013 18.6 1.3 0.0021 18.0 1.3 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 GAM25025.1 - 0.032 14.4 2.6 0.045 13.9 2.6 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.6 GAM25025.1 - 0.059 13.8 0.2 1 9.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain C1_2 PF03107.16 GAM25025.1 - 0.08 13.3 1.9 0.45 10.9 2.1 1.8 1 1 0 1 1 1 0 C1 domain zf-C4_ClpX PF06689.13 GAM25025.1 - 0.26 11.2 0.2 0.26 11.2 0.2 2.2 3 0 0 3 3 3 0 ClpX C4-type zinc finger DUF1364 PF07102.12 GAM25025.1 - 0.27 11.1 3.6 6.5 6.7 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1364) F-box PF00646.33 GAM25026.1 - 3.3e-06 26.8 2.8 1.5e-05 24.7 2.8 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM25026.1 - 8.3e-06 25.6 0.7 1.8e-05 24.5 0.7 1.6 1 0 0 1 1 1 1 F-box-like CTD_bind PF04818.13 GAM25026.1 - 0.00061 20.6 0.1 0.011 16.6 0.1 3.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. PHAT PF09246.10 GAM25026.1 - 0.0066 16.3 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 PHAT Ank_4 PF13637.6 GAM25026.1 - 0.056 14.0 0.7 0.65 10.7 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM25026.1 - 0.088 13.4 0.0 0.39 11.3 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) bZIP_1 PF00170.21 GAM25027.1 - 1.6e-09 37.7 14.6 1.6e-09 37.7 14.6 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 GAM25027.1 - 1.1e-07 32.2 11.3 1.1e-07 32.2 11.3 3.3 3 0 0 3 3 3 1 bZIP Maf transcription factor bZIP_2 PF07716.15 GAM25027.1 - 4.8e-05 23.3 11.5 0.0002 21.4 11.5 2.2 1 0 0 1 1 1 1 Basic region leucine zipper FlaC_arch PF05377.11 GAM25027.1 - 0.44 11.0 3.9 0.32 11.4 1.3 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CCP_MauG PF03150.14 GAM25027.1 - 3.7 8.2 10.0 22 5.6 6.8 2.7 2 1 0 2 2 2 0 Di-haem cytochrome c peroxidase Thiolase_N PF00108.23 GAM25028.1 - 6e-85 284.7 0.0 9.1e-85 284.1 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAM25028.1 - 1.9e-44 150.3 1.0 4.8e-44 149.0 0.6 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAM25028.1 - 6.7e-05 22.6 0.3 0.0018 17.9 0.2 2.4 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAM25028.1 - 0.015 15.3 0.5 10 6.2 0.0 3.3 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain Glutaredoxin PF00462.24 GAM25029.1 - 2.2e-18 66.2 0.0 1.2e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 GAM25029.1 - 2.7e-13 49.8 0.2 7.1e-13 48.4 0.2 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 GAM25029.1 - 1.6e-05 25.1 0.8 0.0013 19.1 0.1 3.1 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.6 GAM25029.1 - 0.00054 20.4 0.4 0.011 16.2 0.1 2.9 1 1 2 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.21 GAM25029.1 - 0.00081 19.3 1.0 0.0099 15.8 0.1 2.8 2 2 1 3 3 3 1 AhpC/TSA family XH PF03469.14 GAM25029.1 - 0.044 13.7 0.1 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 XH domain HyaE PF07449.11 GAM25029.1 - 0.062 13.3 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DUF393 PF04134.12 GAM25030.1 - 5.6e-29 101.8 0.2 6.9e-29 101.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 DUF2428 PF10350.9 GAM25031.1 - 2.7e-78 263.0 0.0 1.6e-77 260.4 0.0 2.3 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 GAM25031.1 - 5.5e-06 26.2 1.3 0.63 10.4 0.0 6.6 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 GAM25031.1 - 0.13 12.8 1.0 1.7e+02 2.8 0.0 5.5 5 0 0 5 5 5 0 HEAT-like repeat DNA_pol_B_2 PF03175.13 GAM25032.1 - 2.3e-07 30.1 4.4 2.1e-05 23.6 4.4 2.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral AAA_16 PF13191.6 GAM25034.1 - 0.00097 19.6 0.0 0.0029 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 GAM25034.1 - 0.0077 16.6 0.1 0.097 13.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM25034.1 - 0.027 14.7 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain FNIP PF05725.12 GAM25035.1 - 3.9e-31 107.0 11.8 5.6e-15 55.2 0.0 6.7 5 2 0 5 5 5 5 FNIP Repeat 7tm_2 PF00002.24 GAM25036.1 - 1.2e-06 28.1 10.6 2.5e-06 27.0 10.6 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 GAM25036.1 - 0.00016 20.9 15.2 0.00047 19.4 15.3 1.6 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 GAM25036.1 - 0.018 15.1 0.4 0.067 13.3 0.1 2.1 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Frizzled PF01534.17 GAM25036.1 - 0.027 13.5 12.6 2.2 7.2 9.6 2.6 1 1 1 3 3 3 0 Frizzled/Smoothened family membrane region DUF1435 PF07256.12 GAM25036.1 - 5.5 7.2 8.4 14 5.9 0.8 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1435) GATA PF00320.27 GAM25037.1 - 3.8e-16 58.4 3.1 6.9e-16 57.6 3.1 1.5 1 0 0 1 1 1 1 GATA zinc finger G3P_antiterm PF04309.12 GAM25037.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator T3SS_needle_F PF09392.10 GAM25037.1 - 5.1 7.4 6.7 6.9 7.0 0.2 2.7 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Pacs-1 PF10254.9 GAM25038.1 - 7.9e-35 120.6 3.1 7.9e-35 120.6 3.1 5.2 3 1 1 4 4 4 1 PACS-1 cytosolic sorting protein Serglycin PF04360.12 GAM25038.1 - 0.82 9.6 20.0 0.044 13.7 6.5 3.8 4 0 0 4 4 4 0 Serglycin Polyketide_cyc PF03364.20 GAM25039.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF4448 PF14610.6 GAM25039.1 - 0.051 13.3 0.3 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EGF_2 PF07974.13 GAM25039.1 - 0.074 13.4 17.0 0.17 12.3 17.0 1.6 1 0 0 1 1 1 0 EGF-like domain S-l_SbsC_C PF18316.1 GAM25039.1 - 0.082 13.4 0.8 0.082 13.4 0.8 2.5 3 0 0 3 3 3 0 S-layer protein SbsC C-terminal domain SKG6 PF08693.10 GAM25039.1 - 0.15 11.5 5.9 0.3 10.5 5.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Flp1_like PF16982.5 GAM25039.1 - 6.5 6.2 10.3 37 3.8 10.2 2.3 1 1 0 1 1 1 0 Putative Flagellin, Flp1-like, domain bMG10 PF17973.1 GAM25041.1 - 1.9e-20 73.4 0.0 4.1e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M PF00207.22 GAM25041.1 - 3.5e-07 30.0 0.0 1.2e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin family MG2 PF01835.19 GAM25041.1 - 7.5e-07 29.5 0.0 4.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 MG2 domain A2M_BRD PF07703.14 GAM25041.1 - 3.9e-06 27.3 0.5 0.015 15.7 0.0 4.0 4 1 0 4 4 4 2 Alpha-2-macroglobulin bait region domain bMG3 PF11974.8 GAM25041.1 - 0.055 13.5 0.3 1.3 9.1 0.3 2.7 1 1 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Glyco_transf_20 PF00982.21 GAM25042.1 - 1e-172 575.1 0.0 3.4e-172 573.4 0.0 1.8 3 0 0 3 3 3 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAM25042.1 - 7e-37 126.8 0.0 1.5e-36 125.7 0.0 1.6 1 1 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 GAM25042.1 - 0.00028 20.5 0.1 0.0014 18.2 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 SUIM_assoc PF16619.5 GAM25042.1 - 0.017 15.2 1.4 0.038 14.1 1.4 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DRTGG PF07085.12 GAM25042.1 - 0.046 13.5 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 DRTGG domain DUF2590 PF10761.9 GAM25042.1 - 0.062 13.4 0.5 0.85 9.8 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2590) Med15 PF09606.10 GAM25042.1 - 0.083 11.6 3.0 0.11 11.1 3.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RabGAP-TBC PF00566.18 GAM25043.1 - 1.3e-55 188.4 1.7 2e-54 184.5 0.1 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 GAM25043.1 - 3.9e-25 88.0 3.0 1.8e-13 50.4 0.1 2.5 2 0 0 2 2 2 2 GRAM domain bPH_2 PF03703.14 GAM25043.1 - 0.019 15.2 0.1 0.11 12.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial PH domain HEPN_Swt1 PF18731.1 GAM25043.1 - 0.43 10.9 3.5 4.7 7.6 0.1 3.4 4 1 1 5 5 5 0 Swt1-like HEPN CBFD_NFYB_HMF PF00808.23 GAM25044.1 - 1e-09 38.5 1.1 1.9e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MPM1 PF17234.2 GAM25044.1 - 0.00086 19.6 11.2 0.0011 19.3 11.2 1.1 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 DUF4770 PF15994.5 GAM25044.1 - 0.0098 16.2 1.3 0.012 15.9 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4770) Bromo_TP PF07524.13 GAM25044.1 - 0.011 15.7 0.1 0.053 13.5 0.0 1.9 1 1 1 2 2 2 0 Bromodomain associated Afi1 PF07792.12 GAM25044.1 - 0.011 16.2 4.2 0.013 16.0 4.2 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Mucin PF01456.17 GAM25044.1 - 0.026 14.5 2.2 0.032 14.2 2.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein UBA_e1_thiolCys PF10585.9 GAM25044.1 - 0.026 14.4 9.0 0.035 14.0 9.0 1.1 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site DUF908 PF06012.12 GAM25044.1 - 0.04 13.3 3.8 0.04 13.3 3.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RNA_pol_Rpc4 PF05132.14 GAM25044.1 - 0.052 14.0 6.9 0.048 14.1 6.9 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 GAM25044.1 - 0.09 11.1 9.7 0.086 11.1 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 GAM25044.1 - 0.1 11.6 5.8 0.12 11.3 5.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 GAM25044.1 - 0.11 12.7 7.2 0.12 12.5 7.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Rtf2 PF04641.12 GAM25044.1 - 0.15 11.4 13.5 0.15 11.4 13.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DDHD PF02862.17 GAM25044.1 - 0.15 12.2 5.4 0.16 12.1 5.4 1.1 1 0 0 1 1 1 0 DDHD domain Macoilin PF09726.9 GAM25044.1 - 0.17 10.4 10.8 0.2 10.2 10.8 1.0 1 0 0 1 1 1 0 Macoilin family Histone PF00125.24 GAM25044.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.1 2 0 0 2 2 1 0 Core histone H2A/H2B/H3/H4 Na_K-ATPase PF00287.18 GAM25044.1 - 0.21 10.7 6.4 0.26 10.4 6.3 1.3 1 1 0 1 1 1 0 Sodium / potassium ATPase beta chain Vfa1 PF08432.10 GAM25044.1 - 0.32 11.3 17.7 0.39 11.0 17.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.11 GAM25044.1 - 0.42 8.7 10.7 0.47 8.5 10.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Atrophin-1 PF03154.15 GAM25044.1 - 0.46 8.7 11.5 0.58 8.4 11.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family CLN3 PF02487.17 GAM25044.1 - 0.47 9.4 2.6 0.49 9.4 2.6 1.1 1 0 0 1 1 1 0 CLN3 protein EOS1 PF12326.8 GAM25044.1 - 0.9 9.4 2.7 1.3 9.0 2.7 1.2 1 0 0 1 1 1 0 N-glycosylation protein GNAT_acetyltr_2 PF13718.6 GAM25044.1 - 1.1 8.6 5.1 1.7 8.0 5.1 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 CobT PF06213.12 GAM25044.1 - 1.2 8.5 14.7 1.4 8.3 14.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YABBY PF04690.13 GAM25044.1 - 1.9 9.0 8.1 12 6.4 3.0 2.1 2 0 0 2 2 2 0 YABBY protein Topoisom_I_N PF02919.15 GAM25044.1 - 4.1 6.8 12.2 6.6 6.2 12.2 1.4 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RP-C_C PF11800.8 GAM25044.1 - 4.5 7.3 8.3 6 6.9 8.3 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF3915 PF13054.6 GAM25044.1 - 7.2 6.6 7.8 3.7 7.6 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) Peptidase_S49_N PF08496.10 GAM25044.1 - 8 6.5 14.1 12 6.0 14.1 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal MATH PF00917.26 GAM25045.1 - 4.2e-06 26.9 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 MATH domain Mycoplasma_p37 PF06646.11 GAM25045.1 - 0.072 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 High affinity transport system protein p37 HTH_40 PF14493.6 GAM25046.1 - 0.22 12.0 1.3 19 5.8 0.3 3.1 2 2 1 3 3 3 0 Helix-turn-helix domain Beta-lactamase PF00144.24 GAM25046.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase vATP-synt_E PF01991.18 GAM25047.1 - 5.2e-67 225.1 4.4 6.1e-67 224.9 4.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.6 GAM25047.1 - 0.085 13.3 3.1 0.3 11.5 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) DivIVA PF05103.13 GAM25047.1 - 2.2 8.4 15.2 5.8 7.0 5.1 2.3 1 1 1 2 2 2 0 DivIVA protein SKG6 PF08693.10 GAM25048.1 - 0.15 11.5 2.6 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Ribonuclease_3 PF00636.26 GAM25049.1 - 0.00022 21.8 0.0 0.00059 20.4 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain FRB_dom PF08771.11 GAM25049.1 - 0.0046 17.3 1.3 0.0089 16.4 1.3 1.5 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain Ribonuclease_3 PF00636.26 GAM25050.1 - 3e-07 31.0 2.0 6.5e-07 29.9 0.0 2.4 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAM25050.1 - 0.0017 18.5 3.7 0.015 15.5 0.0 2.9 2 2 1 3 3 3 1 Ribonuclease-III-like MSA-2c PF12238.8 GAM25050.1 - 1.3 9.0 5.5 2.9 7.8 0.7 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c Ribosomal_L23 PF00276.20 GAM25051.1 - 1.7e-12 47.5 5.3 2.3e-12 47.1 5.3 1.3 1 1 0 1 1 1 1 Ribosomal protein L23 DUF2723 PF11028.8 GAM25052.1 - 2.3e-35 122.0 8.2 2.3e-35 122.0 8.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) zf-MYND PF01753.18 GAM25053.1 - 2.1e-07 30.9 11.7 2.1e-07 30.9 11.7 4.8 2 1 2 4 4 4 1 MYND finger F-box PF00646.33 GAM25054.1 - 0.0024 17.7 0.4 0.051 13.5 0.7 3.0 2 0 0 2 2 2 1 F-box domain DUF2935 PF11155.8 GAM25054.1 - 0.16 12.3 1.6 22 5.4 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) COS PF18568.1 GAM25055.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain ACOX PF01756.19 GAM25056.1 - 6.7e-18 64.9 0.0 1.2e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 GAM25056.1 - 1.8e-14 53.7 0.0 2.9e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAM25056.1 - 4.7e-08 33.4 0.0 1.1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 GAM25056.1 - 1.2e-06 29.1 0.2 2.4e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_N PF02771.16 GAM25056.1 - 0.0039 17.8 0.0 0.01 16.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Hint PF01079.20 GAM25056.1 - 0.41 10.1 1.8 3.6 7.1 0.5 2.2 2 0 0 2 2 2 0 Hint module Cut8 PF08559.10 GAM25057.1 - 5.6e-33 114.5 5.5 5.6e-33 114.5 5.5 2.6 1 1 1 2 2 2 1 Cut8, nuclear proteasome tether protein DSHCT PF08148.12 GAM25057.1 - 0.08 12.6 2.3 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 DSHCT (NUC185) domain PAT1 PF09770.9 GAM25057.1 - 0.1 10.8 35.1 0.15 10.3 35.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.11 GAM25057.1 - 6 5.2 26.8 8.8 4.7 26.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 CtaG_Cox11 PF04442.14 GAM25058.1 - 1.7e-55 187.2 0.2 1.7e-55 187.2 0.2 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF2722 PF10846.8 GAM25058.1 - 5.5e-06 25.6 4.9 6e-06 25.5 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 GAM25058.1 - 0.00077 20.1 6.1 0.0013 19.4 6.1 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Velvet PF11754.8 GAM25058.1 - 0.0015 18.5 0.7 0.0019 18.2 0.7 1.1 1 0 0 1 1 1 1 Velvet factor DDHD PF02862.17 GAM25058.1 - 0.0039 17.4 0.1 0.0039 17.4 0.1 1.1 1 0 0 1 1 1 1 DDHD domain DUF5308 PF17233.2 GAM25058.1 - 0.0041 17.4 0.5 0.0053 17.0 0.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Presenilin PF01080.17 GAM25058.1 - 0.0056 15.5 3.3 0.0074 15.1 3.3 1.1 1 0 0 1 1 1 1 Presenilin CDC45 PF02724.14 GAM25058.1 - 0.0095 14.3 2.8 0.012 14.0 2.8 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF4407 PF14362.6 GAM25058.1 - 0.017 14.5 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 GAM25058.1 - 0.025 14.4 3.4 0.035 13.9 3.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 GAM25058.1 - 0.058 13.4 3.7 0.079 12.9 3.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Connexin PF00029.19 GAM25058.1 - 0.062 13.1 0.7 0.085 12.6 0.7 1.2 1 0 0 1 1 1 0 Connexin Alba PF01918.21 GAM25058.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Alba Neur_chan_memb PF02932.16 GAM25058.1 - 0.1 12.7 4.8 0.14 12.2 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 GAM25058.1 - 0.1 12.0 7.4 0.15 11.5 7.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Serinc PF03348.15 GAM25058.1 - 0.11 11.3 0.4 0.14 11.0 0.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Orf78 PF06024.12 GAM25058.1 - 0.13 12.5 0.7 0.26 11.6 0.7 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Ureide_permease PF07168.11 GAM25058.1 - 0.15 10.8 0.2 0.2 10.3 0.2 1.1 1 0 0 1 1 1 0 Ureide permease Zip PF02535.22 GAM25058.1 - 0.16 11.2 2.3 0.21 10.8 2.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CLN3 PF02487.17 GAM25058.1 - 0.21 10.6 1.1 0.28 10.2 1.1 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4603 PF15376.6 GAM25058.1 - 0.22 8.9 6.9 0.3 8.4 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF4834 PF16118.5 GAM25058.1 - 0.59 11.1 9.2 1.5 9.9 9.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) eIF-3_zeta PF05091.12 GAM25058.1 - 0.87 8.5 10.0 1.2 8.0 10.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.7 GAM25058.1 - 0.97 7.5 6.1 1.2 7.1 6.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.13 GAM25058.1 - 1.1 8.9 5.4 1.6 8.5 5.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spt20 PF12090.8 GAM25058.1 - 1.2 8.7 25.3 1.8 8.1 25.3 1.2 1 0 0 1 1 1 0 Spt20 family FAM176 PF14851.6 GAM25058.1 - 2.7 7.7 5.2 4.9 6.8 5.2 1.4 1 0 0 1 1 1 0 FAM176 family CobT PF06213.12 GAM25058.1 - 3.4 7.0 18.2 4.8 6.5 18.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT V_ATPase_I PF01496.19 GAM25058.1 - 4.4 5.1 7.9 5.8 4.7 7.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FXR_C1 PF16096.5 GAM25058.1 - 4.6 7.5 7.3 8 6.7 7.3 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 G0-G1_switch_2 PF15103.6 GAM25058.1 - 4.9 7.6 10.5 20 5.6 7.6 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 NPR3 PF03666.13 GAM25058.1 - 10 4.8 11.4 14 4.3 11.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 UPF0121 PF03661.13 GAM25059.1 - 6.5e-26 91.2 9.3 8.5e-26 90.8 9.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Pex14_N PF04695.13 GAM25059.1 - 0.00094 19.9 11.4 0.002 18.8 11.4 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4282 PF14110.6 GAM25059.1 - 0.0019 18.9 0.8 0.0055 17.4 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) Opi1 PF08618.10 GAM25059.1 - 0.087 12.1 4.5 0.11 11.7 4.5 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 SLC12 PF03522.15 GAM25059.1 - 0.1 11.6 0.7 0.13 11.2 0.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF515 PF04415.12 GAM25059.1 - 0.11 10.8 1.9 0.16 10.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FAM60A PF15396.6 GAM25059.1 - 0.19 11.7 1.8 0.28 11.2 1.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Suf PF05843.14 GAM25059.1 - 0.36 10.8 8.0 0.51 10.3 8.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Lin-8 PF03353.15 GAM25059.1 - 1.4 8.5 7.4 1.9 8.0 7.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 GAM25059.1 - 1.8 8.5 12.7 2.4 8.1 12.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 GAM25059.1 - 2.7 8.4 7.7 4.7 7.6 7.7 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Gemini_mov PF01708.16 GAM25059.1 - 3.8 7.3 10.7 0.31 10.8 1.5 3.3 3 1 1 4 4 4 0 Geminivirus putative movement protein EGF_Tenascin PF18720.1 GAM25060.1 - 0.013 15.5 8.6 0.04 14.0 8.6 1.9 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 GAM25060.1 - 0.016 15.5 8.6 0.046 14.1 8.6 1.8 1 0 0 1 1 1 0 EGF-like domain Toxin_2 PF00451.19 GAM25060.1 - 0.69 10.3 4.3 1.5 9.2 4.3 1.6 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 TIG PF01833.24 GAM25061.1 - 6.7e-20 71.0 34.9 1e-06 28.7 1.6 5.7 4 2 1 5 5 5 4 IPT/TIG domain EGF_2 PF07974.13 GAM25061.1 - 3.9e-06 27.1 13.1 1e-05 25.8 13.1 1.7 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 GAM25061.1 - 0.0064 16.8 10.6 0.017 15.4 10.6 1.8 1 0 0 1 1 1 1 EGF-like domain CS PF04969.16 GAM25061.1 - 0.025 15.6 2.1 1.1 10.4 0.0 3.7 4 0 0 4 4 4 0 CS domain CrgA PF06781.12 GAM25061.1 - 0.041 13.9 0.1 0.099 12.7 0.1 1.6 1 0 0 1 1 1 0 Cell division protein CrgA hEGF PF12661.7 GAM25061.1 - 0.12 13.0 8.7 0.4 11.4 8.7 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 GAM25061.1 - 1.4 9.0 10.2 3.3 7.9 10.2 1.7 1 0 0 1 1 1 0 Tenascin EGF domain TIG PF01833.24 GAM25062.1 - 8.7e-08 32.1 39.8 0.00032 20.7 2.6 6.7 5 2 1 6 6 6 3 IPT/TIG domain EGF_2 PF07974.13 GAM25062.1 - 0.00015 22.1 12.7 0.00032 21.0 12.7 1.5 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 GAM25062.1 - 0.11 12.9 8.2 0.2 12.0 8.2 1.5 1 0 0 1 1 1 0 EGF-like domain DUF4215 PF13948.6 GAM25062.1 - 0.31 11.5 5.6 3 8.3 6.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) Toxin_2 PF00451.19 GAM25062.1 - 1.2 9.5 5.7 2.6 8.4 5.7 1.5 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 EGF_Tenascin PF18720.1 GAM25062.1 - 1.5 9.0 11.5 4.1 7.5 10.5 2.1 2 0 0 2 2 2 0 Tenascin EGF domain TIG PF01833.24 GAM25063.1 - 1.7e-08 34.4 53.7 0.015 15.3 1.0 7.2 4 3 3 7 7 7 5 IPT/TIG domain EGF_2 PF07974.13 GAM25063.1 - 0.00071 19.9 10.6 0.0018 18.6 10.6 1.7 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 GAM25063.1 - 0.0078 16.5 10.2 0.023 15.0 10.2 1.9 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 GAM25063.1 - 0.06 13.4 6.0 0.55 10.3 6.4 2.3 2 0 0 2 2 2 0 Tenascin EGF domain EB PF01683.18 GAM25063.1 - 0.12 12.7 6.3 0.19 12.0 4.4 2.2 2 0 0 2 2 2 0 EB module Sec3_C_2 PF15278.6 GAM25063.1 - 0.42 11.0 2.3 23 5.4 0.1 2.5 2 0 0 2 2 2 0 Sec3 exocyst complex subunit hEGF PF12661.7 GAM25063.1 - 7.3 7.4 12.9 0.26 12.0 6.1 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF IPK PF03770.16 GAM25064.1 - 1.1e-36 126.6 1.3 1.1e-36 126.6 1.3 1.9 2 1 0 2 2 2 1 Inositol polyphosphate kinase HNF-1_N PF04814.13 GAM25064.1 - 0.0065 17.1 3.7 0.44 11.1 0.1 2.9 3 0 0 3 3 3 2 Hepatocyte nuclear factor 1 (HNF-1), N terminus BBP2_2 PF10082.9 GAM25064.1 - 0.17 10.7 1.1 6 5.6 0.4 2.1 2 0 0 2 2 2 0 Putative beta-barrel porin 2 RAB3GAP2_N PF14655.6 GAM25065.1 - 3.9e-119 398.6 0.1 7.8e-119 397.6 0.0 1.5 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Zip PF02535.22 GAM25065.1 - 0.41 9.8 3.1 0.9 8.7 3.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Mcm10 PF09332.11 GAM25065.1 - 1.3 8.3 7.6 2.2 7.6 7.6 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Sporozoite_P67 PF05642.11 GAM25065.1 - 2 6.4 16.8 3.3 5.7 14.1 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen COPI_C PF06957.11 GAM25065.1 - 2.7 6.6 7.4 5.4 5.7 7.4 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus BUD22 PF09073.10 GAM25065.1 - 5 6.4 25.6 0.79 9.0 21.0 1.8 2 0 0 2 2 2 0 BUD22 Hid1 PF12722.7 GAM25065.1 - 7.3 4.6 13.1 11 4.0 13.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPRY PF00622.28 GAM25066.1 - 0.00036 20.6 0.1 0.00094 19.3 0.1 1.7 1 1 0 1 1 1 1 SPRY domain CLP1_P PF16575.5 GAM25067.1 - 0.093 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SNF2_N PF00176.23 GAM25068.1 - 2.6e-62 210.6 0.0 4.2e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM25068.1 - 7.7e-15 55.2 0.0 3.1e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.29 GAM25068.1 - 6e-10 38.9 7.8 6e-10 38.9 7.8 2.5 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_3 PF13920.6 GAM25068.1 - 1.2e-05 25.1 4.9 1.2e-05 25.1 4.9 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM25068.1 - 3.5e-05 23.7 6.0 8.5e-05 22.5 6.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAM25068.1 - 3.5e-05 23.6 7.6 3.5e-05 23.6 7.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM25068.1 - 0.00073 19.3 7.7 0.00073 19.3 7.7 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM25068.1 - 0.0037 17.6 7.7 0.0037 17.6 7.7 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 GAM25068.1 - 0.009 16.2 8.1 0.009 16.2 8.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING HAD_SAK_2 PF18143.1 GAM25068.1 - 0.039 14.3 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Prok-RING_4 PF14447.6 GAM25068.1 - 0.1 12.5 6.3 0.27 11.1 6.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAM25068.1 - 0.32 11.3 12.1 0.17 12.2 3.9 2.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAM25068.1 - 7.3 6.7 8.6 1.4 9.0 2.2 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Dynamin_N PF00350.23 GAM25069.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family FNIP PF05725.12 GAM25070.1 - 1.9e-65 216.8 25.5 7.8e-13 48.4 0.0 5.3 1 1 6 7 7 7 7 FNIP Repeat FNIP PF05725.12 GAM25071.1 - 3.7e-39 132.6 13.7 4.5e-11 42.7 0.2 6.1 3 1 2 6 6 6 6 FNIP Repeat FNIP PF05725.12 GAM25072.1 - 4.6e-45 151.5 12.2 2e-13 50.2 0.1 5.7 6 0 0 6 6 6 4 FNIP Repeat FNIP PF05725.12 GAM25073.1 - 3.6e-70 231.9 11.3 2.5e-13 49.9 0.2 6.2 1 1 5 8 8 8 8 FNIP Repeat F-box-like PF12937.7 GAM25073.1 - 9.3e-05 22.3 0.5 0.00052 19.9 0.2 2.4 2 0 0 2 2 2 1 F-box-like FNIP PF05725.12 GAM25074.1 - 1.4e-61 204.4 14.8 7.6e-15 54.8 0.4 6.9 3 1 3 8 8 8 7 FNIP Repeat Nuf2 PF03800.14 GAM25075.1 - 0.0058 16.8 0.2 0.0081 16.3 0.2 1.4 1 0 0 1 1 1 1 Nuf2 family HTH_31 PF13560.6 GAM25075.1 - 0.059 13.7 0.0 0.34 11.3 0.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 GAM25075.1 - 0.26 11.3 3.0 0.61 10.1 2.7 1.8 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain Pyridoxal_deC PF00282.19 GAM25076.1 - 7.2e-20 71.0 0.0 1.4e-19 70.0 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAM25076.1 - 7.6e-05 21.8 0.0 0.00019 20.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Inh PF02974.14 GAM25076.1 - 0.021 14.9 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 Protease inhibitor Inh Tyr-DNA_phospho PF06087.12 GAM25077.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase DUF5063 PF16702.5 GAM25077.1 - 0.07 13.5 0.9 0.14 12.6 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) Importin_rep_4 PF18808.1 GAM25077.1 - 0.083 13.2 0.2 0.21 11.9 0.2 1.6 1 0 0 1 1 1 0 Importin repeat ubiquitin PF00240.23 GAM25078.1 - 3e-34 116.6 0.4 3.9e-34 116.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 GAM25078.1 - 1.4e-30 104.9 12.6 2.1e-30 104.3 12.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 GAM25078.1 - 6.6e-16 57.9 0.4 8.8e-16 57.5 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAM25078.1 - 3.3e-05 24.3 0.1 0.00013 22.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 GAM25078.1 - 0.0048 17.2 0.1 0.0079 16.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAM25078.1 - 0.0094 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM25078.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 GAM25078.1 - 0.021 14.8 0.7 6.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 GAM25078.1 - 0.063 13.8 0.1 0.067 13.8 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Thioredoxin PF00085.20 GAM25079.1 - 1.1e-32 112.1 0.0 2.4e-15 56.4 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 GAM25079.1 - 2e-08 34.4 1.2 4.9e-06 26.6 0.3 3.4 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 GAM25079.1 - 0.00028 21.3 0.1 3.5 8.1 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAM25079.1 - 0.00049 20.2 0.1 0.39 10.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 GAM25079.1 - 0.04 14.3 0.1 23 5.4 0.0 3.7 3 1 0 3 3 3 0 Thioredoxin-like N2227 PF07942.12 GAM25080.1 - 1.5e-61 207.9 0.2 2.5e-61 207.3 0.2 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 GAM25080.1 - 0.0092 15.8 0.0 0.032 14.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM25080.1 - 0.038 14.7 0.0 0.12 13.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAM25080.1 - 0.049 14.3 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ARA70 PF12489.8 GAM25080.1 - 0.52 10.5 6.6 0.12 12.6 3.1 1.7 1 1 1 2 2 2 0 Nuclear coactivator BUD22 PF09073.10 GAM25080.1 - 1.6 8.0 8.2 2.3 7.4 8.2 1.1 1 0 0 1 1 1 0 BUD22 Ground-like PF04155.18 GAM25080.1 - 2.6 8.8 5.7 43 4.9 0.2 3.5 4 0 0 4 4 4 0 Ground-like domain Tmemb_14 PF03647.13 GAM25081.1 - 6.6e-27 94.1 9.7 7.4e-27 93.9 9.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 GAM25081.1 - 0.0081 16.4 4.2 0.01 16.1 4.2 1.1 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 zf-RING_UBOX PF13445.6 GAM25082.1 - 0.00056 19.9 4.8 0.0019 18.2 4.8 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAM25082.1 - 0.0018 18.4 4.1 0.01 16.0 4.1 2.4 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAM25082.1 - 0.0021 17.9 1.4 0.0021 17.9 1.4 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 GAM25082.1 - 0.0049 16.7 5.3 0.013 15.4 5.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM25082.1 - 0.0052 16.6 6.8 0.019 14.8 6.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM25082.1 - 0.017 15.0 5.0 0.072 13.0 5.0 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM25082.1 - 0.18 11.7 6.7 0.61 10.0 6.7 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Sina PF03145.16 GAM25082.1 - 0.21 11.5 0.2 0.21 11.5 0.2 2.5 3 1 0 3 3 3 0 Seven in absentia protein family CEP19 PF14933.6 GAM25082.1 - 0.25 11.7 3.0 3.6 7.9 0.0 2.4 2 0 0 2 2 2 0 CEP19-like protein DUF4482 PF14818.6 GAM25082.1 - 1.3 9.9 8.5 0.2 12.5 1.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) zf-rbx1 PF12678.7 GAM25082.1 - 1.7 9.0 6.7 4.2 7.7 6.0 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAM25082.1 - 2 8.8 10.3 0.66 10.4 6.2 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 GAM25082.1 - 9.3 6.3 15.1 0.16 12.0 7.6 2.0 2 0 0 2 2 1 0 zinc-RING finger domain Got1 PF04178.12 GAM25083.1 - 4.1e-30 104.5 17.3 5.8e-30 104.0 17.3 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Claudin_2 PF13903.6 GAM25083.1 - 0.0013 18.6 1.9 0.0013 18.6 1.9 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF5305 PF17231.2 GAM25083.1 - 0.25 10.7 1.7 1.2 8.5 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Wzy_C PF04932.15 GAM25083.1 - 3.9 7.1 11.1 31 4.2 10.6 2.2 1 1 0 1 1 1 0 O-Antigen ligase Alg14 PF08660.11 GAM25084.1 - 1.5e-59 200.8 0.0 2.7e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.16 GAM25084.1 - 5.2e-15 55.8 0.0 1.3e-14 54.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain FKBP_C PF00254.28 GAM25085.1 - 8.1e-36 122.2 0.0 1e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SAM35 PF10806.8 GAM25086.1 - 0.02 15.1 3.2 0.031 14.6 3.2 1.3 1 0 0 1 1 1 0 SAM35, subunit of SAM coomplex Slp PF03843.13 GAM25086.1 - 0.1 12.0 4.9 0.17 11.2 4.9 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family DUF5352 PF17303.2 GAM25086.1 - 0.11 12.3 0.6 0.14 12.0 0.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5352) Pex14_N PF04695.13 GAM25086.1 - 1.4 9.5 14.3 1.8 9.2 14.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 GAM25086.1 - 3.6 6.2 5.7 3.4 6.3 5.7 1.0 1 0 0 1 1 1 0 Presenilin EIF4E-T PF10477.9 GAM25086.1 - 5.5 5.7 17.7 5.4 5.7 17.7 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PAT1 PF09770.9 GAM25086.1 - 5.6 5.1 20.9 5.8 5.1 20.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NDT80_PhoG PF05224.12 GAM25087.1 - 1.3e-22 81.0 2.6 4.6e-21 75.9 0.1 2.6 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.6 GAM25088.1 - 1.3e-10 41.4 1.2 1.5e-10 41.2 0.1 1.7 2 0 0 2 2 2 1 Chaperone of endosialidase MRF_C1 PF13887.6 GAM25088.1 - 6.4e-10 38.0 0.8 3.7e-09 35.6 0.1 2.3 2 0 0 2 2 2 1 Myelin gene regulatory factor -C-terminal domain 1 DUF1664 PF07889.12 GAM25088.1 - 0.046 13.8 0.3 0.09 12.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF913 PF06025.12 GAM25090.1 - 0.28 10.1 7.4 0.35 9.8 7.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PEMT PF04191.13 GAM25091.1 - 1.3e-30 105.9 5.0 1.3e-30 105.9 5.0 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase Ras PF00071.22 GAM25092.1 - 6.5e-64 214.4 0.3 7.6e-64 214.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM25092.1 - 7.7e-36 122.9 0.3 1.3e-35 122.2 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM25092.1 - 2.5e-18 66.1 0.2 3e-18 65.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM25092.1 - 2e-06 27.3 0.1 2.3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAM25092.1 - 2.9e-06 27.3 0.1 0.067 13.1 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM25092.1 - 6.5e-06 26.2 0.1 4.3e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM25092.1 - 2.1e-05 24.1 0.4 9e-05 22.1 0.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAM25092.1 - 5.3e-05 22.7 0.0 8.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GAM25092.1 - 0.0018 17.8 0.0 0.5 9.9 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA PF00004.29 GAM25092.1 - 0.0022 18.4 0.0 1 9.8 0.0 2.3 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 GAM25092.1 - 0.014 14.8 0.0 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 GAM25092.1 - 0.026 14.8 0.0 0.16 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain LepB_N PF18640.1 GAM25092.1 - 0.032 13.9 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 LepB N-terminal domain AAA_29 PF13555.6 GAM25092.1 - 0.041 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM25092.1 - 0.049 14.0 0.0 0.09 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 GAM25092.1 - 0.05 12.9 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Septin NACHT PF05729.12 GAM25092.1 - 0.052 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 GAM25092.1 - 0.11 13.0 0.2 0.17 12.4 0.2 1.6 1 1 0 1 1 1 0 ABC transporter BTG PF07742.12 GAM25093.1 - 3.1e-20 72.1 0.0 5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 BTG family UBN_AB PF14075.6 GAM25094.1 - 4.6e-10 39.6 0.9 1.2e-07 31.7 0.0 5.5 2 2 1 3 3 3 2 Ubinuclein conserved middle domain HUN PF08729.10 GAM25094.1 - 1.4e-09 37.8 8.4 1.4e-09 37.8 8.4 3.3 2 0 0 2 2 2 1 HPC2 and ubinuclein domain HTH_40 PF14493.6 GAM25094.1 - 0.011 16.2 1.2 0.042 14.3 0.6 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain RhoGAP PF00620.27 GAM25096.1 - 1.2e-31 109.6 0.0 1.8e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain SKG6 PF08693.10 GAM25096.1 - 0.0072 15.7 1.4 0.013 14.9 1.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 GAM25096.1 - 0.024 14.4 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AMA-1 PF02430.15 GAM25096.1 - 0.03 13.3 0.2 0.044 12.7 0.2 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 tRNA_anti-like PF12869.7 GAM25096.1 - 0.096 12.3 0.1 4.5 6.9 0.2 2.6 2 0 0 2 2 2 0 tRNA_anti-like ECSCR PF15820.5 GAM25096.1 - 0.12 12.2 0.2 0.31 10.9 0.2 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Insulin_TMD PF17870.1 GAM25096.1 - 0.18 11.9 2.8 0.37 10.9 2.8 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ribosomal_L3 PF00297.22 GAM25097.1 - 3.7e-178 592.2 7.0 4.2e-178 592.0 7.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 E3_UFM1_ligase PF09743.9 GAM25097.1 - 0.00079 19.1 0.3 0.0011 18.6 0.3 1.2 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 Mycobact_memb PF05423.13 GAM25100.1 - 0.035 14.0 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 Mycobacterium membrane protein FNIP PF05725.12 GAM25101.1 - 1.8e-38 130.4 3.2 2.2e-07 30.9 0.0 6.7 4 3 1 6 6 6 5 FNIP Repeat Ribosomal_L30 PF00327.20 GAM25102.1 - 1.2e-20 73.1 1.2 1.2e-20 73.1 1.2 2.1 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 GAM25102.1 - 5.1e-19 68.3 9.9 5.1e-19 68.3 9.9 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Elong_Iki1 PF10483.9 GAM25103.1 - 1.6e-13 50.9 8.5 1.5e-09 37.8 8.5 3.6 1 1 0 1 1 1 1 Elongator subunit Iki1 Glyco_transf_8C PF08437.10 GAM25104.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal USP7_ICP0_bdg PF12436.8 GAM25105.1 - 1.9e-54 184.5 0.0 4.1e-54 183.4 0.0 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 GAM25105.1 - 5.2e-52 176.9 0.2 8e-52 176.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 GAM25105.1 - 1.5e-44 152.2 0.0 1e-43 149.5 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 GAM25105.1 - 7.6e-23 81.6 0.0 1.9e-22 80.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 GAM25105.1 - 7e-12 45.5 0.1 2.7e-11 43.6 0.1 2.1 1 0 0 1 1 1 1 MATH domain Ubiquitin_2 PF14560.6 GAM25105.1 - 0.023 15.2 0.0 0.071 13.6 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain ubiquitin PF00240.23 GAM25105.1 - 0.26 11.1 3.0 5.9 6.7 0.0 3.6 4 0 0 4 4 4 0 Ubiquitin family HATPase_c PF02518.26 GAM25106.1 - 1.2e-25 90.2 0.0 3.2e-25 88.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM25106.1 - 9.9e-21 74.0 0.1 4.6e-20 71.9 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAM25106.1 - 7.7e-18 64.3 0.0 1.8e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 GAM25106.1 - 1.8e-05 25.1 0.0 3.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 GAF domain PAS_4 PF08448.10 GAM25106.1 - 0.0046 17.2 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 GAM25106.1 - 0.0047 17.2 0.1 0.012 15.9 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 GAM25106.1 - 0.015 15.3 0.1 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 PAS fold DUF1043 PF06295.12 GAM25106.1 - 4.4 7.3 6.0 16 5.5 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1043) Folliculin_C PF16692.5 GAM25108.1 - 1.4e-56 191.8 1.1 2e-56 191.2 0.0 1.9 2 0 0 2 2 2 1 Folliculin C-terminal domain Folliculin PF11704.8 GAM25108.1 - 8.4e-40 136.6 0.4 8.4e-40 136.6 0.4 2.1 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport SH3_9 PF14604.6 GAM25109.1 - 7.7e-18 64.1 0.2 1.5e-17 63.1 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM25109.1 - 9.8e-14 50.8 0.0 2.3e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM25109.1 - 2.7e-13 49.3 0.1 4.8e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 GAM25109.1 - 3e-12 46.6 0.0 3e-12 46.6 0.0 3.6 4 2 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain HR1 PF02185.16 GAM25109.1 - 0.0012 18.9 4.3 0.0012 18.9 4.3 3.1 2 2 0 2 2 1 1 Hr1 repeat FapA PF03961.13 GAM25109.1 - 0.011 14.3 14.4 0.13 10.8 1.0 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A Spc7 PF08317.11 GAM25109.1 - 0.022 13.6 24.8 0.3 9.9 14.1 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein zf-C4H2 PF10146.9 GAM25109.1 - 0.043 14.1 10.5 0.06 13.6 4.0 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Vps5 PF09325.10 GAM25109.1 - 0.11 12.0 21.3 0.35 10.4 12.7 3.6 2 2 1 3 3 3 0 Vps5 C terminal like GAS PF13851.6 GAM25109.1 - 0.15 11.4 27.2 0.017 14.4 5.4 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 GAM25109.1 - 0.17 12.0 30.5 0.25 11.4 12.9 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 GAM25109.1 - 0.37 10.6 18.2 2.3 8.0 8.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 GAM25109.1 - 0.76 7.6 9.1 4.4 5.1 0.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PCRF PF03462.18 GAM25109.1 - 2.4 8.0 18.5 0.27 11.1 0.4 2.9 2 1 1 3 3 3 0 PCRF domain EzrA PF06160.12 GAM25109.1 - 3.3 5.8 25.8 2.2 6.3 3.8 2.9 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Uds1 PF15456.6 GAM25109.1 - 5.6 7.1 20.0 0.47 10.6 2.8 2.4 2 0 0 2 2 2 0 Up-regulated During Septation LRR_6 PF13516.6 GAM25110.1 - 8e-11 41.1 46.7 0.0016 18.3 0.2 12.1 12 0 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.7 GAM25110.1 - 0.0034 17.7 0.8 0.0034 17.7 0.8 8.3 4 4 3 7 7 7 2 Leucine Rich repeats (2 copies) Alpha_GJ PF03229.13 GAM25110.1 - 0.089 13.4 0.0 0.29 11.7 0.0 1.8 1 0 0 1 1 1 0 Alphavirus glycoprotein J F-box-like PF12937.7 GAM25110.1 - 0.096 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 F-box-like WD40 PF00400.32 GAM25111.1 - 5.6e-22 77.6 17.5 0.00014 22.6 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM25111.1 - 2e-08 34.4 3.7 0.014 15.7 0.5 4.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM25111.1 - 1.3e-07 31.3 3.0 0.0075 15.6 0.0 2.6 2 1 0 2 2 2 2 WD40-like domain F-box-like PF12937.7 GAM25111.1 - 4.8e-07 29.6 0.3 8.1e-07 28.8 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM25111.1 - 1.7e-05 24.5 0.2 3.7e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 GAM25111.1 - 0.00034 19.4 9.0 0.99 8.0 0.1 4.8 2 1 2 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 GAM25111.1 - 0.0017 18.4 0.8 0.16 12.0 0.0 3.3 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region F-box_4 PF15966.5 GAM25111.1 - 0.002 18.0 0.0 0.0063 16.4 0.0 1.8 1 0 0 1 1 1 1 F-box PQQ PF01011.21 GAM25111.1 - 0.0087 16.0 0.2 7.1 6.8 0.0 3.6 3 0 0 3 3 3 1 PQQ enzyme repeat 4HBT_2 PF13279.6 GAM25111.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase-like superfamily TMC PF07810.13 GAM25112.1 - 4.8e-09 36.8 0.2 4.8e-09 36.8 0.2 2.8 2 1 0 2 2 2 1 TMC domain Anoctamin PF04547.12 GAM25112.1 - 1.5e-08 33.9 21.6 7.9e-08 31.6 21.6 2.1 1 1 0 1 1 1 1 Calcium-activated chloride channel RSN1_7TM PF02714.15 GAM25112.1 - 0.092 12.0 30.0 0.02 14.2 20.7 3.1 2 2 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate Insulin_TMD PF17870.1 GAM25112.1 - 0.82 9.8 8.2 0.09 12.9 1.9 2.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment ANAPC4_WD40 PF12894.7 GAM25113.1 - 1.2e-10 41.5 0.2 0.38 11.1 0.0 6.2 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAM25113.1 - 1.7e-07 31.8 12.7 0.034 15.0 0.4 8.1 9 0 0 9 9 9 1 WD domain, G-beta repeat BBS2_N PF14781.6 GAM25113.1 - 2.7e-05 24.0 0.5 0.032 14.1 0.2 3.7 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal DUF1668 PF07893.13 GAM25113.1 - 0.0086 15.5 0.1 3.2 7.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1668) WD40_3 PF15911.5 GAM25113.1 - 0.009 16.0 0.1 0.061 13.3 0.0 2.5 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_2 PF13360.6 GAM25113.1 - 0.028 14.0 0.1 5.3 6.6 0.0 3.0 2 1 1 3 3 3 0 PQQ-like domain PAN_3 PF08277.12 GAM25113.1 - 0.039 13.8 0.1 0.6 10.0 0.2 2.6 2 0 0 2 2 2 0 PAN-like domain VID27 PF08553.10 GAM25113.1 - 0.059 12.4 0.2 0.41 9.6 0.2 2.3 2 1 0 2 2 2 0 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 GAM25113.1 - 0.096 11.6 4.6 6.2 5.7 0.1 3.8 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAM25113.1 - 0.12 12.3 0.0 19 5.4 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat COPIIcoated_ERV PF07970.12 GAM25114.1 - 3.9e-52 177.3 2.9 5.2e-52 176.9 1.3 1.8 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAM25114.1 - 1.1e-20 73.7 0.1 2.3e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pex14_N PF04695.13 GAM25114.1 - 1 10.0 9.8 0.24 12.0 6.1 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4106 PF13388.6 GAM25114.1 - 1.8 7.7 10.9 2.6 7.2 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) TMEM144 PF07857.12 GAM25115.1 - 1.8e-79 267.1 23.9 2.1e-79 266.9 23.9 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 GAM25115.1 - 4.5e-10 39.3 7.3 4.5e-10 39.3 7.3 2.7 2 1 1 3 3 3 2 Sugar transport protein DMT_YdcZ PF04657.13 GAM25115.1 - 0.0079 16.5 11.9 0.0079 16.5 11.9 2.4 2 0 0 2 2 2 1 Putative inner membrane exporter, YdcZ LRR_6 PF13516.6 GAM25116.1 - 7.2e-06 25.6 9.5 1.1 9.5 0.0 6.1 5 0 0 5 5 5 2 Leucine Rich repeat Rot1 PF10681.9 GAM25116.1 - 0.0054 16.3 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal LRR_4 PF12799.7 GAM25116.1 - 0.031 14.7 9.3 1.4 9.4 0.7 5.1 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Herpes_pp85 PF04637.12 GAM25116.1 - 0.046 12.1 4.4 0.087 11.2 4.4 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) LRR_8 PF13855.6 GAM25116.1 - 0.069 12.9 7.5 0.42 10.4 0.2 4.0 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 GAM25116.1 - 0.1 13.2 9.6 40 5.3 0.0 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat CCDC24 PF15669.5 GAM25116.1 - 0.15 11.9 3.1 0.33 10.8 3.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family NleF_casp_inhib PF16809.5 GAM25116.1 - 0.75 9.7 5.6 0.47 10.4 0.1 3.0 4 0 0 4 4 4 0 NleF caspase inhibitor PPR_3 PF13812.6 GAM25117.1 - 0.063 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Pentatricopeptide repeat domain KMP11 PF03037.16 GAM25117.1 - 0.097 13.5 0.9 1.1 10.1 0.4 2.8 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 Rap_GAP PF02145.15 GAM25118.1 - 2.4e-58 196.8 0.1 3.8e-58 196.1 0.1 1.3 1 0 0 1 1 1 1 Rap/ran-GAP RNA_POL_M_15KD PF02150.16 GAM25119.1 - 2.3e-09 37.0 2.9 2.3e-09 37.0 2.9 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 GAM25119.1 - 9.1e-08 31.8 10.5 1e-07 31.7 4.2 3.2 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) Nudix_N_2 PF14803.6 GAM25119.1 - 0.00045 20.1 0.1 0.00045 20.1 0.1 2.9 3 0 0 3 3 3 1 Nudix N-terminal Cys_rich_KTR PF14205.6 GAM25119.1 - 0.0013 18.5 10.2 0.13 12.1 0.6 3.2 2 1 1 3 3 3 2 Cysteine-rich KTR zf-RRPl_C4 PF17026.5 GAM25119.1 - 0.0029 17.7 5.8 0.034 14.2 4.8 2.3 1 1 1 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type DpnI PF06044.12 GAM25119.1 - 0.017 14.7 4.6 0.098 12.3 0.4 2.1 1 1 1 2 2 2 0 Dam-replacing family Auto_anti-p27 PF06677.12 GAM25119.1 - 0.023 14.8 8.7 0.24 11.6 2.2 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 GAM25119.1 - 0.035 14.1 8.3 0.76 9.8 0.3 2.6 2 2 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 GAM25119.1 - 0.18 11.5 12.4 0.26 11.1 2.5 2.9 2 2 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-RING_7 PF02591.15 GAM25119.1 - 0.3 11.3 5.5 10 6.4 0.0 3.6 4 0 0 4 4 3 0 C4-type zinc ribbon domain Terminase_GpA PF05876.12 GAM25119.1 - 0.34 9.4 5.3 0.078 11.5 2.2 1.5 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) CK_II_beta PF01214.18 GAM25119.1 - 0.36 10.6 7.8 2 8.2 0.1 3.1 1 1 1 2 2 2 0 Casein kinase II regulatory subunit HscB_4_cys PF18256.1 GAM25119.1 - 0.41 10.5 8.3 5.9 6.8 0.1 3.6 4 0 0 4 4 4 0 Co-chaperone HscB tetracysteine metal binding motif zf-H2C2_2 PF13465.6 GAM25119.1 - 0.44 11.1 11.2 5.7 7.5 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 GAM25119.1 - 0.48 10.4 11.9 2.9 7.9 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 GAM25119.1 - 0.68 10.0 9.4 0.68 10.0 0.2 2.9 2 1 0 2 2 2 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 GAM25119.1 - 0.72 9.9 13.8 0.3 11.1 2.7 3.1 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Trm112p PF03966.16 GAM25119.1 - 1.1 9.9 4.0 12 6.5 1.7 2.7 2 1 0 2 2 2 0 Trm112p-like protein NADH-G_4Fe-4S_3 PF10588.9 GAM25119.1 - 1.1 8.8 10.6 0.67 9.5 0.2 3.3 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zinc_ribbon_2 PF13240.6 GAM25119.1 - 1.5 8.6 12.2 1.9 8.3 0.2 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Opy2 PF09463.10 GAM25119.1 - 1.7 9.1 11.9 0.94 9.8 0.2 3.6 4 0 0 4 4 4 0 Opy2 protein zinc_ribbon_9 PF14369.6 GAM25119.1 - 1.7 8.9 12.1 5.7 7.3 0.1 3.7 3 1 0 3 3 3 0 zinc-ribbon zf-ribbon_3 PF13248.6 GAM25119.1 - 2.2 7.8 0.0 2.2 7.8 0.0 3.7 4 0 0 4 4 4 0 zinc-ribbon domain PHD PF00628.29 GAM25119.1 - 3 7.8 13.6 17 5.4 1.7 3.3 2 2 0 2 2 2 0 PHD-finger CoiA PF06054.11 GAM25119.1 - 3.2 6.8 7.8 4.3 6.4 0.0 2.9 2 1 1 3 3 3 0 Competence protein CoiA-like family PhnA_Zn_Ribbon PF08274.12 GAM25119.1 - 5.4 7.1 11.4 9.7 6.2 0.1 4.0 4 0 0 4 4 4 0 PhnA Zinc-Ribbon NOB1_Zn_bind PF08772.11 GAM25119.1 - 6.6 7.0 11.3 4.2 7.6 0.2 3.5 3 1 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-ACC PF17848.1 GAM25119.1 - 8.2 6.6 14.9 4.9 7.3 0.2 4.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain RdRP PF05183.12 GAM25120.1 - 1.2e-129 433.7 0.0 4.3e-129 431.8 0.0 2.0 2 0 0 2 2 2 1 RNA dependent RNA polymerase Helicase_C PF00271.31 GAM25120.1 - 2e-18 66.8 0.7 7.7e-18 64.9 0.7 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM25120.1 - 9.8e-17 61.5 0.1 1.7e-15 57.5 0.1 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM25120.1 - 2.7e-16 59.9 0.3 9.1e-16 58.1 0.3 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase MyTH4 PF00784.17 GAM25120.1 - 0.079 13.5 0.0 0.37 11.3 0.0 2.2 1 0 0 1 1 1 0 MyTH4 domain Mesd PF10185.9 GAM25120.1 - 0.082 12.8 2.2 2.4 8.1 0.6 2.7 2 0 0 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor TIP49 PF06068.13 GAM25121.1 - 1e-153 511.7 5.3 1e-153 511.7 5.3 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 GAM25121.1 - 7.6e-28 96.5 1.2 2.7e-27 94.7 1.2 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 GAM25121.1 - 1.8e-08 34.8 3.8 4e-05 24.0 0.1 3.1 3 1 1 4 4 4 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAM25121.1 - 1.6e-07 31.2 0.8 0.0019 18.0 0.1 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 GAM25121.1 - 7.7e-06 25.4 0.3 1.5e-05 24.5 0.3 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 GAM25121.1 - 1.9e-05 24.9 0.4 0.079 13.2 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.6 GAM25121.1 - 2.6e-05 24.6 0.4 0.00012 22.4 0.4 2.0 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAM25121.1 - 4.5e-05 23.2 0.2 0.047 13.4 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 GAM25121.1 - 6.1e-05 23.0 1.0 0.039 13.9 0.2 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM25121.1 - 0.0002 21.8 0.4 0.00084 19.8 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 GAM25121.1 - 0.00072 19.0 1.1 0.032 13.6 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 GAM25121.1 - 0.0058 16.0 0.3 0.01 15.2 0.3 1.5 1 0 0 1 1 1 1 KaiC PIF1 PF05970.14 GAM25121.1 - 0.0093 15.2 1.3 0.51 9.5 0.3 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_25 PF13481.6 GAM25121.1 - 0.012 15.2 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAM25121.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 GAM25121.1 - 0.02 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 GAM25121.1 - 0.028 13.7 0.3 0.056 12.7 0.3 1.4 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.15 GAM25121.1 - 0.04 13.9 1.0 5.1 7.1 0.2 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.6 GAM25121.1 - 0.048 14.1 1.6 0.82 10.1 0.5 3.0 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAM25121.1 - 0.054 13.0 0.5 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 GAM25121.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 GAM25121.1 - 0.086 12.8 0.1 0.27 11.2 0.1 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RVT_1 PF00078.27 GAM25122.1 - 3.7e-34 118.2 0.0 4.7e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MBOAT_2 PF13813.6 GAM25125.1 - 0.02 15.2 1.0 0.028 14.7 1.0 1.2 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Methyltransf_23 PF13489.6 GAM25126.1 - 1.1e-08 35.1 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM25126.1 - 1.7e-08 34.4 0.0 2.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM25126.1 - 2.2e-07 31.4 0.0 3.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAM25126.1 - 7.2e-07 29.1 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 GAM25126.1 - 1.2e-06 29.2 0.1 2.2e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM25126.1 - 5.3e-06 27.1 0.0 8.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 GAM25126.1 - 0.022 14.2 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB NodS PF05401.11 GAM25126.1 - 0.043 13.4 0.1 0.061 12.9 0.1 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) Beach PF02138.18 GAM25127.1 - 8e-126 419.0 2.5 1.4e-125 418.3 0.6 2.5 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.32 GAM25127.1 - 7.8e-14 51.9 14.6 0.004 17.9 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat PH_BEACH PF14844.6 GAM25127.1 - 8.8e-12 45.0 0.2 9.4e-11 41.7 0.0 3.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 GAM25127.1 - 7.3e-10 39.2 0.1 3e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily SUIM_assoc PF16619.5 GAM25127.1 - 1.2e-05 25.3 23.6 0.065 13.3 5.7 4.3 3 0 0 3 3 3 3 Unstructured region C-term to UIM in Ataxin3 DUF4800 PF16057.5 GAM25127.1 - 0.00038 19.8 4.5 0.00038 19.8 4.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) PEX11 PF05648.14 GAM25127.1 - 0.49 9.8 7.1 41 3.5 0.1 3.9 3 0 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) RhoGEF PF00621.20 GAM25129.1 - 3.5e-21 76.3 6.2 1.2e-17 64.8 0.8 3.1 2 1 1 3 3 3 2 RhoGEF domain PH PF00169.29 GAM25129.1 - 2.1e-06 28.2 0.3 1e-05 26.0 0.1 2.3 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 GAM25129.1 - 4.3e-06 26.7 0.1 2e-05 24.6 0.1 2.2 1 0 0 1 1 1 1 PH domain IQ PF00612.27 GAM25129.1 - 7.5e-06 25.3 0.1 1.6e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH_10 PF15411.6 GAM25129.1 - 0.0068 16.7 1.0 0.033 14.5 0.1 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain Ntox15 PF15604.6 GAM25129.1 - 0.042 14.0 4.2 0.19 11.9 4.2 2.1 1 0 0 1 1 1 0 Novel toxin 15 zf_C2H2_10 PF18414.1 GAM25129.1 - 0.053 13.1 0.2 0.15 11.6 0.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger zf-Di19 PF05605.12 GAM25129.1 - 0.17 12.2 0.0 0.46 10.8 0.0 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF445 PF04286.12 GAM25129.1 - 3.5 7.3 8.9 1.5 8.6 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF445) GDPD PF03009.17 GAM25130.1 - 4.7e-49 167.5 0.1 7.3e-49 166.8 0.1 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ThaI PF15514.6 GAM25130.1 - 0.14 11.8 0.1 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease ThaI CBM_20 PF00686.19 GAM25131.1 - 2.3e-14 53.1 0.1 2.3e-14 53.1 0.1 1.8 2 0 0 2 2 2 1 Starch binding domain TFIIA PF03153.13 GAM25131.1 - 0.0046 17.0 8.2 0.0055 16.8 8.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 GAM25131.1 - 0.011 16.1 3.2 0.015 15.7 3.2 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF1198 PF06711.11 GAM25131.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) YppG PF14179.6 GAM25131.1 - 0.53 11.0 15.1 1.4 9.7 15.1 1.7 1 0 0 1 1 1 0 YppG-like protein Spt20 PF12090.8 GAM25131.1 - 0.62 9.6 20.3 0.9 9.1 20.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 GAM25131.1 - 0.76 8.7 15.6 0.97 8.3 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Androgen_recep PF02166.16 GAM25131.1 - 3.5 6.4 12.2 4.9 5.9 12.2 1.2 1 0 0 1 1 1 0 Androgen receptor HEAT_2 PF13646.6 GAM25132.1 - 2.6e-30 104.7 16.3 2.3e-14 53.5 0.5 2.8 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 GAM25132.1 - 3.6e-29 98.4 3.7 3.2e-05 24.2 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 GAM25132.1 - 4e-12 45.3 6.3 0.022 15.0 0.2 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 GAM25132.1 - 1.1e-08 35.4 4.5 0.0024 18.3 0.1 4.1 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 GAM25132.1 - 0.0017 18.4 0.4 1.7 8.7 0.1 3.7 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vitellogenin_N PF01347.22 GAM25132.1 - 0.03 12.7 0.2 0.21 9.9 0.0 2.0 2 0 0 2 2 2 0 Lipoprotein amino terminal region GP57 PF17594.2 GAM25132.1 - 0.072 12.8 1.0 9.6 6.0 0.0 3.2 3 0 0 3 3 3 0 Phage Tail fiber assembly helper gene product 57 Chorismate_bind PF00425.18 GAM25132.1 - 0.1 12.1 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 chorismate binding enzyme Arm PF00514.23 GAM25132.1 - 0.44 10.6 2.0 15 5.8 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Actin PF00022.19 GAM25133.1 - 4.4e-142 473.5 0.0 4.9e-142 473.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAM25133.1 - 3.3e-05 22.9 0.0 0.0019 17.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein RCC1 PF00415.18 GAM25134.1 - 1.2e-53 179.5 22.7 1.3e-07 32.1 0.0 13.9 13 1 0 13 13 13 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM25134.1 - 5.5e-28 96.2 42.8 1.3e-06 28.0 0.7 12.9 14 0 0 14 14 14 9 Regulator of chromosome condensation (RCC1) repeat hSac2 PF12456.8 GAM25134.1 - 1.7e-13 50.3 0.6 3.2e-13 49.4 0.6 1.4 1 0 0 1 1 1 1 Inositol phosphatase Hira PF07569.11 GAM25134.1 - 0.0045 16.7 0.0 0.38 10.4 0.0 3.6 3 0 0 3 3 3 1 TUP1-like enhancer of split SNF2_N PF00176.23 GAM25136.1 - 2.5e-32 112.0 0.0 2.5e-32 112.0 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM25136.1 - 7.8e-11 42.3 0.0 7.8e-11 42.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HARP PF07443.13 GAM25136.1 - 0.066 12.9 0.4 0.26 10.9 0.0 2.2 3 0 0 3 3 3 0 HepA-related protein (HARP) DUF2126 PF09899.9 GAM25136.1 - 5.1 5.0 10.3 7.6 4.5 10.3 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF775 PF05603.12 GAM25136.1 - 6 6.3 18.4 14 5.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF775) DnaJ_C PF01556.18 GAM25137.1 - 3e-37 128.0 0.6 4.1e-37 127.5 0.6 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAM25137.1 - 5.4e-28 96.9 2.8 9e-28 96.2 2.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAM25137.1 - 1.8e-14 53.8 19.2 3.7e-14 52.8 19.2 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAM25137.1 - 6.5e-09 35.6 10.6 2.8e-05 24.0 1.6 2.9 3 0 0 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 GAM25137.1 - 0.0005 20.1 7.7 0.12 12.5 0.3 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 GAM25137.1 - 0.018 14.7 7.2 0.11 12.1 0.3 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Cytochrom_c3_2 PF14537.6 GAM25137.1 - 0.03 14.8 5.5 0.03 14.8 5.5 2.6 1 1 1 2 2 2 0 Cytochrome c3 TFIIS_C PF01096.18 GAM25137.1 - 0.094 12.6 0.4 0.094 12.6 0.4 3.6 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) PADR1 PF08063.12 GAM25137.1 - 0.12 12.1 7.1 4.1 7.3 0.1 3.6 3 0 0 3 3 3 0 PADR1 (NUC008) domain Cytochrome_C7 PF14522.6 GAM25137.1 - 0.14 12.1 11.9 1.4 8.9 11.8 2.5 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Cytochrom_CIII PF02085.16 GAM25137.1 - 0.59 10.5 9.7 0.1 12.9 4.8 2.1 1 1 1 2 2 2 0 Class III cytochrome C family DUF2072 PF09845.9 GAM25137.1 - 5.8 7.2 9.4 0.97 9.7 5.4 1.8 2 0 0 2 2 2 0 Zn-ribbon containing protein zinc-ribbons_6 PF07191.12 GAM25137.1 - 8.9 6.4 12.0 85 3.2 1.2 2.3 1 1 1 2 2 2 0 zinc-ribbons CAF1C_H4-bd PF12265.8 GAM25138.1 - 1.8e-18 66.6 1.5 7.3e-17 61.4 0.2 3.0 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GAM25138.1 - 1.8e-16 60.2 14.5 4.5e-06 27.3 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM25138.1 - 1.3e-07 31.8 1.3 0.00072 19.8 0.2 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Pes-10 PF07149.11 GAM25138.1 - 0.69 8.9 23.3 0.062 12.4 0.3 2.3 2 0 0 2 2 2 0 Pes-10 PNISR PF15996.5 GAM25138.1 - 5.6 7.2 15.7 4.3 7.6 8.3 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DEAD PF00270.29 GAM25139.1 - 1.8e-41 141.8 3.0 1.8e-40 138.6 0.6 3.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM25139.1 - 1.2e-22 80.4 0.0 7.1e-22 77.9 0.0 2.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAM25139.1 - 8.5e-16 57.9 0.7 1.1e-14 54.3 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 GAM25139.1 - 0.0032 17.7 1.0 0.23 11.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain DDE_3 PF13358.6 GAM25140.1 - 0.0096 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease eIF-5_eIF-2B PF01873.17 GAM25140.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Pkinase PF00069.25 GAM25141.1 - 3e-52 177.6 0.0 3.9e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25141.1 - 4e-36 124.6 0.0 5.6e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 GAM25141.1 - 5.1e-05 23.0 0.1 0.32 10.6 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GAM25141.1 - 0.00086 18.7 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 GAM25141.1 - 0.18 10.9 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Tubulin PF00091.25 GAM25142.1 - 4.9e-70 235.7 0.0 9.3e-70 234.8 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAM25142.1 - 5.5e-41 139.7 0.0 8.7e-41 139.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAM25142.1 - 1.1e-06 28.9 0.0 2.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 GAM25142.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 GAM25142.1 - 0.062 12.5 0.2 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 Tubulin like Pur_ac_phosph_N PF16656.5 GAM25143.1 - 1.2e-06 29.0 0.0 2.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 GAM25143.1 - 6.2e-06 26.9 0.3 1.3e-05 25.8 0.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 7TMR-DISM_7TM PF07695.11 GAM25143.1 - 6 6.7 14.5 4.6 7.1 11.0 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling EMC3_TMCO1 PF01956.16 GAM25144.1 - 2.9e-36 124.7 0.3 3.4e-36 124.5 0.3 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Synaptobrevin PF00957.21 GAM25144.1 - 0.00057 19.6 1.1 0.001 18.8 1.1 1.3 1 0 0 1 1 1 1 Synaptobrevin CHD5 PF04420.14 GAM25144.1 - 0.0091 15.9 2.5 0.034 14.0 2.5 1.8 1 1 0 1 1 1 1 CHD5-like protein DivIC PF04977.15 GAM25144.1 - 0.056 13.2 2.2 0.1 12.4 2.1 1.4 1 1 0 1 1 1 0 Septum formation initiator MutS_V PF00488.21 GAM25145.1 - 3.6e-45 154.3 0.0 1e-44 152.8 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 GAM25145.1 - 4.7e-25 88.9 0.2 1.4e-24 87.4 0.1 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 GAM25145.1 - 0.00019 21.7 0.0 0.00067 20.0 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 GAM25145.1 - 0.014 15.7 0.0 0.059 13.7 0.0 2.2 1 0 0 1 1 1 0 MutS family domain IV MSC PF09402.10 GAM25146.1 - 0.19 11.1 1.4 0.46 9.9 1.2 1.6 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain DUF3482 PF11981.8 GAM25146.1 - 0.22 10.9 0.1 0.29 10.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) RRM_1 PF00076.22 GAM25147.1 - 1.2e-55 185.2 0.4 1.3e-20 73.0 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM25147.1 - 1.3e-07 31.3 0.0 0.0046 16.5 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 GAM25147.1 - 2.6e-06 27.6 0.0 0.0025 18.0 0.0 3.1 3 0 0 3 3 3 1 BRCA1-associated protein 2 RRM_7 PF16367.5 GAM25147.1 - 1.9e-05 24.7 0.0 0.49 10.6 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 GAM25147.1 - 5.6e-05 23.1 0.0 1.2 9.2 0.0 3.5 3 1 0 3 3 3 2 RNA binding domain RRM_3 PF08777.11 GAM25147.1 - 0.00061 19.8 0.3 4.8 7.3 0.2 3.2 2 1 1 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 GAM25147.1 - 0.016 15.3 1.1 4.4 7.4 0.0 3.0 4 0 0 4 4 4 0 Limkain b1 PHM7_cyt PF14703.6 GAM25147.1 - 0.026 14.8 6.3 1.5 9.0 0.1 4.3 3 2 3 6 6 6 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 GAM25147.1 - 0.033 14.0 0.0 7.4 6.5 0.0 3.2 3 0 0 3 3 3 0 Occluded RNA-recognition motif RCC1 PF00415.18 GAM25148.1 - 1.9e-90 297.3 20.8 4.2e-17 62.5 0.1 8.5 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM25148.1 - 1.5e-38 129.8 38.5 2.2e-08 33.7 1.8 7.6 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Clathrin PF00637.20 GAM25148.1 - 4.9e-06 26.5 4.8 0.0066 16.3 0.6 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS Ycf54 PF10674.9 GAM25148.1 - 0.13 12.6 0.0 0.65 10.3 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) GGDEF PF00990.21 GAM25149.1 - 2.5e-31 108.6 0.0 4.1e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain RNA_pol_RpbG PF16992.5 GAM25149.1 - 0.04 14.0 0.2 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G FAD_binding_1 PF00667.20 GAM25150.1 - 8.4e-34 117.1 0.1 1.6e-33 116.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GAM25150.1 - 4.9e-16 59.3 0.0 1.3e-15 57.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2034 PF10356.9 GAM25151.1 - 1.2e-14 54.2 4.4 1.7e-07 30.8 0.2 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 GAM25151.1 - 5e-06 26.5 0.0 9.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease PP2C PF00481.21 GAM25152.1 - 4.5e-40 137.9 0.2 1.1e-39 136.7 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C E1_dh PF00676.20 GAM25153.1 - 8.8e-97 323.7 0.1 1.1e-96 323.3 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GAM25153.1 - 0.019 14.2 0.0 0.11 11.7 0.0 2.2 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.32 GAM25154.1 - 6.8e-17 61.5 15.9 0.00089 20.0 1.9 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Tom22 PF04281.13 GAM25154.1 - 0.00031 20.5 2.6 0.00031 20.5 2.6 2.7 2 0 0 2 2 2 1 Mitochondrial import receptor subunit Tom22 ANAPC4_WD40 PF12894.7 GAM25154.1 - 0.0017 18.6 0.0 6.3 7.2 0.0 4.3 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain TYA PF01021.19 GAM25154.1 - 0.086 13.2 2.9 0.36 11.2 2.9 2.0 1 0 0 1 1 1 0 TYA transposon protein Cwf_Cwc_15 PF04889.12 GAM25154.1 - 0.21 11.3 25.4 1.6 8.4 5.7 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 GAM25154.1 - 2 8.0 19.1 5.1 6.6 19.1 1.6 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.13 GAM25154.1 - 2.3 8.0 7.6 0.8 9.5 1.6 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.6 GAM25154.1 - 2.6 8.5 15.0 11 6.4 6.6 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SPX PF03105.19 GAM25154.1 - 3.5 7.5 13.7 5.9 6.7 13.7 1.3 1 0 0 1 1 1 0 SPX domain SAPS PF04499.15 GAM25154.1 - 4.1 6.1 6.1 6.9 5.3 6.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein YL1 PF05764.13 GAM25154.1 - 5.3 7.1 21.2 3.2 7.8 1.2 2.5 2 0 0 2 2 2 0 YL1 nuclear protein VIT1 PF01988.19 GAM25155.1 - 2.6e-49 168.0 2.2 3.3e-49 167.7 2.2 1.1 1 0 0 1 1 1 1 VIT family TRI12 PF06609.13 GAM25155.1 - 0.029 12.8 1.7 0.044 12.2 1.7 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) NAD_binding_10 PF13460.6 GAM25155.1 - 0.033 14.1 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Holin_SPP1 PF04688.13 GAM25155.1 - 0.59 10.3 2.6 11 6.3 0.0 3.2 4 0 0 4 4 4 0 SPP1 phage holin UPF0154 PF03672.13 GAM25155.1 - 1.1 9.4 4.8 0.7 10.0 0.3 3.1 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0154) Cyclin_N PF00134.23 GAM25156.1 - 0.041 13.6 0.1 0.088 12.6 0.1 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain EMP24_GP25L PF01105.24 GAM25157.1 - 4.7e-49 166.8 0.2 6e-49 166.5 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RAMP4 PF06624.12 GAM25157.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 PDEase_II PF02112.15 GAM25157.1 - 0.091 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II CBM_26 PF16824.5 GAM25157.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal carbohydrate-binding module VHP PF02209.19 GAM25158.1 - 3.2e-13 49.5 0.6 5.2e-13 48.8 0.6 1.4 1 0 0 1 1 1 1 Villin headpiece domain Ribosomal_L33 PF00471.20 GAM25159.1 - 4.9e-12 46.1 0.2 6.3e-12 45.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 ELMO_CED12 PF04727.13 GAM25160.1 - 7e-08 32.8 1.2 1.4e-07 31.8 0.2 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 GAM25160.1 - 0.0042 17.6 0.1 1.9 9.0 0.1 2.5 1 1 1 2 2 2 2 Pleckstrin homology domain DUF3091 PF11291.8 GAM25160.1 - 0.062 13.5 0.6 0.16 12.2 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) TadF PF16964.5 GAM25160.1 - 0.36 10.6 4.0 2.1 8.0 2.8 2.3 2 1 0 2 2 2 0 Putative tight adherence pilin protein F ELMO_CED12 PF04727.13 GAM25161.1 - 1e-36 126.7 0.1 2.7e-36 125.3 0.0 1.7 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.8 GAM25161.1 - 3.4e-09 36.8 0.1 7.3e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) CIDE-N PF02017.15 GAM25161.1 - 0.098 12.7 0.2 14 5.8 0.0 2.4 2 0 0 2 2 2 0 CIDE-N domain DUF1799 PF08809.11 GAM25161.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) PRCC PF10253.9 GAM25161.1 - 0.91 10.3 7.5 1.7 9.4 7.5 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting RSB_motif PF16294.5 GAM25162.1 - 1.9e-11 44.1 4.6 1.9e-11 44.1 4.6 4.1 2 1 0 2 2 2 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 GAM25162.1 - 6.6e-10 38.5 1.8 6.6e-10 38.5 1.8 2.1 2 0 0 2 2 2 1 SAP domain RRM_1 PF00076.22 GAM25162.1 - 0.0037 17.1 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HeH PF12949.7 GAM25162.1 - 0.08 12.7 0.1 0.08 12.7 0.1 2.0 2 0 0 2 2 2 0 HeH/LEM domain Cwf_Cwc_15 PF04889.12 GAM25162.1 - 0.86 9.3 40.9 0.35 10.6 33.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SSP160 PF06933.11 GAM25162.1 - 1.2 7.3 7.0 2.4 6.3 7.0 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SWI-SNF_Ssr4 PF08549.10 GAM25162.1 - 1.6 7.3 29.8 0.091 11.4 17.4 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) SRP-alpha_N PF04086.13 GAM25162.1 - 1.7 8.5 39.0 1.3 8.9 9.4 2.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal TFIIA PF03153.13 GAM25162.1 - 2.4 8.1 35.5 5.4 6.9 26.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PRCC PF10253.9 GAM25162.1 - 6 7.6 35.9 7.1 7.4 8.5 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting FNIP PF05725.12 GAM25164.1 - 3.1e-62 206.5 17.6 2.2e-17 63.0 2.1 5.8 3 2 4 7 7 7 7 FNIP Repeat SpoVR PF04293.13 GAM25164.1 - 0.021 13.5 0.2 1.2 7.8 0.0 2.5 3 0 0 3 3 3 0 SpoVR like protein DUF1769 PF08588.10 GAM25164.1 - 0.045 14.0 6.8 35 4.7 0.4 5.2 4 1 2 6 6 6 0 Protein of unknown function (DUF1769) 7tm_1 PF00001.21 GAM25166.1 - 4e-06 26.4 0.9 5.2e-06 26.0 0.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 GAM25166.1 - 0.00016 21.1 0.3 0.0002 20.7 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1265 PF06887.14 GAM25166.1 - 0.3 11.1 1.1 0.6 10.1 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) DUF4037 PF13228.6 GAM25167.1 - 1.5e-09 38.5 0.0 5.9e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4037) FNIP PF05725.12 GAM25168.1 - 2.3e-11 43.6 4.8 4.9e-06 26.6 0.4 3.8 2 1 1 3 3 3 3 FNIP Repeat Nop14 PF04147.12 GAM25169.1 - 8.6e-205 682.7 63.7 2.5e-203 677.9 63.7 2.0 1 1 0 1 1 1 1 Nop14-like family A_deaminase PF00962.22 GAM25170.1 - 1.2e-29 103.7 0.0 1.8e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 GAM25170.1 - 8.7e-14 51.6 0.2 1.8e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Pkinase_Tyr PF07714.17 GAM25173.1 - 1.3e-59 201.6 0.0 1.7e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM25173.1 - 4.7e-46 157.3 0.0 7.2e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.22 GAM25173.1 - 2.3e-20 72.6 26.7 2.3e-10 40.6 11.0 2.6 2 0 0 2 2 2 2 LIM domain Haspin_kinase PF12330.8 GAM25173.1 - 4.4e-06 25.9 0.1 0.0001 21.4 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM25173.1 - 2.1e-05 24.5 0.0 3.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAM25173.1 - 9.8e-05 21.8 0.0 0.00024 20.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAM25173.1 - 0.00025 20.0 0.1 0.00049 19.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAM25173.1 - 0.0003 20.2 0.0 0.00057 19.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM25173.1 - 0.0049 16.5 0.0 0.086 12.4 0.0 2.2 2 0 0 2 2 2 1 RIO1 family SOG2 PF10428.9 GAM25173.1 - 3.1 6.9 15.1 4.4 6.4 15.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Sulfotransfer_2 PF03567.14 GAM25174.1 - 7.4e-13 49.0 0.4 7.4e-13 49.0 0.4 1.8 2 0 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 GAM25174.1 - 9.1e-06 24.8 0.6 0.00012 21.1 0.2 2.5 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase Inhibitor_I69 PF13734.6 GAM25174.1 - 0.023 15.1 0.4 0.053 13.9 0.4 1.6 1 0 0 1 1 1 0 Spi protease inhibitor DUF1744 PF08490.12 GAM25175.1 - 5.3e-115 384.2 0.0 9.4e-115 383.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 GAM25175.1 - 5.8e-73 245.9 3.6 5.8e-73 245.9 3.6 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 GAM25175.1 - 3.2e-14 52.5 8.4 1.5e-08 33.8 3.6 4.7 4 1 0 4 4 4 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 GAM25175.1 - 3.6e-06 26.8 0.5 7e-05 22.6 0.5 2.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 GAM25175.1 - 0.00033 20.7 0.1 0.0023 18.0 0.0 2.6 2 1 0 2 2 2 1 RNase_H superfamily Phage_clamp_A PF16790.5 GAM25175.1 - 0.055 13.9 0.4 0.88 10.0 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage clamp loader A subunit Ribosomal_L37e PF01907.19 GAM25175.1 - 0.82 9.9 5.8 16 5.8 0.1 3.7 3 0 0 3 3 3 0 Ribosomal protein L37e Mob1_phocein PF03637.17 GAM25176.1 - 2.2e-51 174.3 0.1 2.9e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family FNIP PF05725.12 GAM25177.1 - 3.8e-23 81.4 1.2 1.5e-09 37.9 0.1 3.4 2 1 1 3 3 3 3 FNIP Repeat LRR_5 PF13306.6 GAM25177.1 - 0.069 13.1 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) SHR-BD PF06650.12 GAM25178.1 - 1.2e-42 146.2 7.7 1.3e-38 132.9 1.6 4.0 2 2 1 3 3 3 3 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 GAM25178.1 - 7.6e-27 94.2 3.0 1.2e-25 90.3 0.1 4.0 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 GAM25178.1 - 9.3e-07 28.5 7.9 0.00015 21.2 3.6 4.6 3 1 0 3 3 3 1 Repeating coiled region of VPS13 FAD-SLDH PF12318.8 GAM25178.1 - 0.044 13.8 0.2 0.092 12.8 0.2 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase RPE65 PF03055.15 GAM25178.1 - 0.055 12.7 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein VPS13 PF16908.5 GAM25179.1 - 1.5e-67 227.8 0.4 1.5e-67 227.8 0.4 2.6 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 GAM25179.1 - 5.6e-45 153.6 14.1 8.7e-45 153.0 5.8 3.0 3 0 0 3 3 3 2 Repeating coiled region of VPS13 Chorein_N PF12624.7 GAM25179.1 - 1.4e-38 131.6 1.4 1.4e-38 131.6 1.4 2.5 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 Ribosomal_L13e PF01294.18 GAM25180.1 - 2.9e-72 242.3 6.7 4.4e-72 241.7 6.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e Use1 PF09753.9 GAM25180.1 - 0.098 12.4 3.8 0.16 11.7 3.8 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 BRCT_3 PF18428.1 GAM25181.1 - 1.5e-16 60.3 0.0 4.1e-15 55.7 0.0 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 GAM25181.1 - 6.4e-14 52.1 5.6 8e-07 29.4 0.3 2.9 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM25181.1 - 8.4e-11 42.1 0.8 8.4e-08 32.5 0.3 3.1 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 GAM25181.1 - 0.00075 19.3 0.2 0.015 15.2 0.1 3.2 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 GAM25181.1 - 0.0041 17.1 0.5 8.7 6.4 0.0 3.6 2 2 0 2 2 2 2 twin BRCT domain LIM PF00412.22 GAM25182.1 - 1.1e-07 31.9 6.0 2.3e-07 31.0 6.0 1.5 1 0 0 1 1 1 1 LIM domain zf-C2H2_6 PF13912.6 GAM25182.1 - 0.034 14.1 1.4 0.073 13.1 1.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger c-SKI_SMAD_bind PF08782.10 GAM25182.1 - 5.7 7.2 5.8 20 5.5 5.8 2.0 1 0 0 1 1 1 0 c-SKI Smad4 binding domain Y_phosphatase2 PF03162.13 GAM25183.1 - 2.3e-62 209.4 0.0 2.6e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GAM25183.1 - 6.3e-07 29.6 0.0 8.9e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GAM25183.1 - 9.8e-05 22.2 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM25183.1 - 0.0022 17.6 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FNIP PF05725.12 GAM25184.1 - 4.2e-48 161.3 11.5 7.7e-10 38.8 0.1 5.4 2 1 3 6 6 6 6 FNIP Repeat N6_N4_Mtase PF01555.18 GAM25185.1 - 2.4e-05 24.2 0.2 0.00043 20.1 0.0 2.6 2 1 0 2 2 2 1 DNA methylase DUF3915 PF13054.6 GAM25185.1 - 0.011 15.8 4.3 0.038 14.0 4.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) SSP160 PF06933.11 GAM25185.1 - 3.5 5.7 13.9 5 5.2 13.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 EF-hand_1 PF00036.32 GAM25186.1 - 1.1e-16 59.1 6.4 1.6e-05 24.1 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 GAM25186.1 - 4.3e-16 59.1 5.2 6.8e-09 36.1 0.2 2.7 1 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM25186.1 - 3.5e-14 51.4 5.7 0.00035 20.3 0.1 4.1 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 GAM25186.1 - 2.3e-12 45.8 8.2 0.00027 20.3 0.8 3.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 GAM25186.1 - 2.8e-12 46.3 5.2 0.0001 22.0 0.3 3.3 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM25186.1 - 1.4e-06 28.5 0.1 0.0078 16.5 0.0 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GAM25186.1 - 1.8e-06 28.2 1.2 0.0089 16.3 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 GAM25186.1 - 7.8e-05 22.6 0.9 0.0031 17.4 0.0 2.7 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 GAM25186.1 - 0.00065 19.5 1.7 2.3 8.1 0.1 3.4 3 1 1 4 4 4 2 EF hand Dockerin_1 PF00404.18 GAM25186.1 - 0.00098 19.3 0.3 0.28 11.4 0.0 2.3 2 0 0 2 2 2 1 Dockerin type I domain EF-hand_11 PF08976.11 GAM25186.1 - 0.1 13.5 0.0 0.26 12.2 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain AICARFT_IMPCHas PF01808.18 GAM25187.1 - 1.3e-75 254.6 0.0 1.7e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme LpxI_C PF06230.11 GAM25187.1 - 0.032 14.1 0.1 1.9 8.3 0.1 2.7 3 0 0 3 3 3 0 LpxI C-terminal domain MGS PF02142.22 GAM25188.1 - 7.1e-26 90.2 0.0 9.3e-26 89.9 0.0 1.2 1 0 0 1 1 1 1 MGS-like domain TIG PF01833.24 GAM25189.1 - 7.4e-06 26.0 2.5 7.4e-06 26.0 2.5 4.7 5 0 0 5 5 5 2 IPT/TIG domain EGF_2 PF07974.13 GAM25189.1 - 0.0022 18.3 14.0 0.0065 16.8 14.0 1.9 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 GAM25189.1 - 0.0091 16.0 11.7 0.027 14.5 11.7 1.9 1 0 0 1 1 1 1 Tenascin EGF domain DUF1011 PF06237.12 GAM25189.1 - 5.5 7.4 8.8 0.35 11.2 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) DUF4564 PF15169.6 GAM25190.1 - 5.4e-41 140.3 0.0 6.7e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) MFS_1 PF07690.16 GAM25191.1 - 6.6e-20 71.3 36.1 6.6e-20 71.3 36.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily AIM5 PF17050.5 GAM25191.1 - 0.012 16.4 0.3 1.1 10.1 0.0 2.3 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 ABC2_membrane_3 PF12698.7 GAM25192.1 - 2.6e-35 122.1 28.2 3.7e-35 121.7 28.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 GAM25192.1 - 1.2e-32 113.0 22.3 1.1e-29 103.3 17.3 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 GAM25192.1 - 7.5e-30 104.2 0.0 1.3e-29 103.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM25192.1 - 1.1e-13 51.7 0.3 2.7e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 GAM25192.1 - 1.1e-11 44.5 11.8 1.7e-11 44.0 11.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3533 PF12051.8 GAM25192.1 - 2.2e-07 30.2 0.1 2.2e-07 30.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3533) SMC_N PF02463.19 GAM25192.1 - 0.0028 17.1 0.2 0.46 9.9 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 GAM25192.1 - 0.017 15.1 0.1 0.63 10.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM25192.1 - 0.019 15.3 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 GAM25192.1 - 0.029 14.1 0.4 6.7 6.3 0.6 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 GAM25192.1 - 0.031 14.7 0.1 0.12 12.8 0.1 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAM25192.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 GAM25192.1 - 0.044 14.1 0.3 0.29 11.4 0.3 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAM25192.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 GAM25192.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 GAM25192.1 - 0.2 12.1 0.9 0.42 11.1 0.6 1.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAM25192.1 - 0.22 11.3 0.2 5.4 6.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain GATA PF00320.27 GAM25193.1 - 6e-16 57.8 4.0 1.4e-15 56.6 4.0 1.7 1 0 0 1 1 1 1 GATA zinc finger Methyltransf_16 PF10294.9 GAM25194.1 - 3.7e-11 43.1 0.0 5.1e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase HECT PF00632.25 GAM25195.1 - 2.2e-62 211.3 0.2 1.2e-61 208.9 0.1 2.4 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 GAM25195.1 - 1.8e-17 63.5 0.2 5e-17 62.1 0.2 1.8 1 0 0 1 1 1 1 SPRY domain PH PF00169.29 GAM25195.1 - 2.4e-17 63.4 0.5 7.6e-17 61.7 0.2 2.2 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 GAM25195.1 - 1.4e-08 35.1 0.5 1.4e-08 35.1 0.5 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain CUB PF00431.20 GAM25195.1 - 0.00088 19.6 0.0 2.8 8.3 0.0 2.8 2 0 0 2 2 2 2 CUB domain PH_11 PF15413.6 GAM25195.1 - 0.087 13.3 3.9 0.062 13.7 0.2 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain PSD2 PF07624.11 GAM25195.1 - 0.096 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) SUIM_assoc PF16619.5 GAM25197.1 - 0.0011 18.9 1.1 0.0011 18.9 1.1 5.6 5 1 0 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 Oxidored_q5_N PF01059.17 GAM25197.1 - 6 7.0 7.3 10 6.3 2.0 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus DUF775 PF05603.12 GAM25198.1 - 8.9e-17 61.3 2.3 1.2e-16 60.8 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) SWIM PF04434.17 GAM25201.1 - 0.035 13.8 0.1 0.035 13.8 0.1 2.2 2 0 0 2 2 2 0 SWIM zinc finger Agenet PF05641.12 GAM25201.1 - 0.089 13.3 0.7 0.28 11.7 0.1 2.1 2 0 0 2 2 2 0 Agenet domain MRC1 PF09444.10 GAM25201.1 - 0.83 10.2 6.3 1.6 9.2 0.3 2.3 1 1 1 2 2 2 0 MRC1-like domain DUF4819 PF16090.5 GAM25202.1 - 0.046 13.8 0.1 0.09 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4819) Agenet PF05641.12 GAM25202.1 - 0.19 12.2 0.6 0.39 11.2 0.3 1.8 2 0 0 2 2 2 0 Agenet domain AAA_35 PF14516.6 GAM25207.1 - 0.032 13.1 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 GAM25207.1 - 0.076 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF745 PF05335.13 GAM25208.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) AAA_16 PF13191.6 GAM25210.1 - 0.048 14.0 0.0 0.069 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 GAM25210.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_19 PF13245.6 GAM25210.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain BRCT PF00533.26 GAM25213.1 - 1.7e-06 28.3 2.6 4.9e-06 26.8 0.4 3.0 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM25213.1 - 1.2e-05 25.6 0.3 0.0013 19.1 0.1 3.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 GAM25213.1 - 0.0001 22.1 6.8 0.00013 21.8 0.4 3.2 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain JIP_LZII PF16471.5 GAM25213.1 - 0.0058 16.8 0.1 0.0058 16.8 0.1 10.6 6 3 5 12 12 12 2 JNK-interacting protein leucine zipper II HALZ PF02183.18 GAM25213.1 - 0.049 13.9 0.3 0.049 13.9 0.3 7.3 8 0 0 8 8 8 0 Homeobox associated leucine zipper FNIP PF05725.12 GAM25217.1 - 1.8e-33 114.4 8.5 5.2e-07 29.7 0.4 10.6 5 2 4 11 11 11 10 FNIP Repeat NPHI_C PF08469.10 GAM25217.1 - 0.13 12.3 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal TruB_N PF01509.18 GAM25218.1 - 7.7e-36 123.7 0.0 1.2e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GAM25218.1 - 0.002 18.2 0.0 0.0052 16.9 0.0 1.7 1 1 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Clp_N PF02861.20 GAM25218.1 - 0.16 12.1 0.0 29 4.9 0.0 2.3 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component FNIP PF05725.12 GAM25220.1 - 4.4e-26 90.8 0.3 6.5e-05 23.0 0.0 8.4 4 1 8 12 12 12 10 FNIP Repeat F-box_5 PF18511.1 GAM25221.1 - 0.02 14.5 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box DUF3430 PF11912.8 GAM25223.1 - 1e-09 38.8 5.6 1.2e-09 38.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Kelch_1 PF01344.25 GAM25224.1 - 0.0005 19.6 6.3 7.8 6.2 0.0 4.9 5 0 0 5 5 5 3 Kelch motif DUF4547 PF15080.6 GAM25224.1 - 0.0055 16.4 0.0 0.0088 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4547) Nsp2a_N PF17896.1 GAM25224.1 - 0.027 13.7 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain Kelch_6 PF13964.6 GAM25224.1 - 0.045 14.1 5.4 9.4 6.7 0.0 3.9 3 1 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 GAM25224.1 - 0.92 9.6 8.1 1.1 9.3 0.2 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain AAA PF00004.29 GAM25225.1 - 2.4e-46 157.4 0.0 3.4e-42 144.0 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 GAM25225.1 - 6.2e-18 64.6 0.7 1.6e-17 63.4 0.7 1.7 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 GAM25225.1 - 3.8e-05 23.4 0.0 0.00014 21.6 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 GAM25225.1 - 3.8e-05 23.9 0.2 0.00014 22.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 GAM25225.1 - 0.00017 21.4 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 GAM25225.1 - 0.0011 19.5 0.9 0.0066 17.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM25225.1 - 0.0011 19.4 0.0 0.0011 19.4 0.0 2.7 4 0 0 4 4 1 1 AAA ATPase domain AAA_14 PF13173.6 GAM25225.1 - 0.0037 17.3 0.0 0.08 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAM25225.1 - 0.012 15.6 0.1 0.098 12.6 0.1 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 GAM25225.1 - 0.017 15.5 0.0 0.053 13.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 GAM25225.1 - 0.018 15.3 12.1 0.14 12.5 0.0 4.6 3 1 1 4 4 4 0 AAA domain RuvB_N PF05496.12 GAM25225.1 - 0.027 14.2 0.0 0.087 12.6 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAM25225.1 - 0.03 14.5 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAM25225.1 - 0.03 13.7 0.0 0.093 12.1 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 GAM25225.1 - 0.052 13.5 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 GAM25225.1 - 0.2 12.2 0.0 0.2 12.2 0.0 3.6 4 1 0 4 4 3 0 ABC transporter Mucin PF01456.17 GAM25225.1 - 8.2 6.4 11.3 22 5.0 11.3 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Hydrolase_3 PF08282.12 GAM25226.1 - 1.3e-58 198.8 0.1 1.4e-58 198.6 0.1 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 GAM25226.1 - 1.3e-15 57.6 0.2 2.3e-08 33.9 0.1 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 GAM25226.1 - 1.1e-08 35.6 0.4 0.0062 16.8 0.0 3.1 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 GAM25226.1 - 8.1e-06 25.1 0.1 0.045 12.9 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase HAD PF12710.7 GAM25226.1 - 2.8e-05 24.6 0.8 0.13 12.7 0.0 3.1 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase MCPVI PF02993.14 GAM25226.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Minor capsid protein VI DDE_Tnp_4 PF13359.6 GAM25228.1 - 1.2e-17 64.1 0.0 1.4e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM25228.1 - 7.8e-08 32.2 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain PHD PF00628.29 GAM25229.1 - 4.5e-24 84.1 38.3 1.2e-11 44.4 8.4 3.8 3 0 0 3 3 3 3 PHD-finger Myb_DNA-binding PF00249.31 GAM25229.1 - 1.3e-05 25.3 0.0 3.7e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain EVE PF01878.18 GAM25229.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.7 1 0 0 1 1 1 1 EVE domain PHD_2 PF13831.6 GAM25229.1 - 0.042 13.4 24.1 0.28 10.8 2.5 4.6 4 0 0 4 4 4 0 PHD-finger Myb_DNA-bind_6 PF13921.6 GAM25229.1 - 0.043 14.1 0.4 0.18 12.1 0.2 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain C1_1 PF00130.22 GAM25229.1 - 0.18 11.7 24.1 0.038 13.9 0.8 4.0 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MLANA PF14991.6 GAM25229.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.5 3 0 0 3 3 3 0 Protein melan-A Prok-RING_1 PF14446.6 GAM25229.1 - 0.2 11.6 22.9 0.37 10.7 4.8 3.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 CBM_20 PF00686.19 GAM25230.1 - 7.5e-20 70.6 0.6 1.4e-19 69.7 0.6 1.5 1 0 0 1 1 1 1 Starch binding domain Pro_isomerase PF00160.21 GAM25232.1 - 4e-50 170.1 0.7 1.6e-49 168.2 0.2 2.1 3 0 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 GAM25232.1 - 1.2e-05 25.9 0.7 0.0018 19.1 0.1 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM25232.1 - 0.009 16.3 0.0 8.4 6.8 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Kelch_5 PF13854.6 GAM25233.1 - 4e-37 125.6 7.9 1.3e-06 28.2 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAM25233.1 - 1.3e-34 117.3 9.9 1.7e-07 31.3 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 GAM25233.1 - 2.9e-34 116.4 14.0 8.4e-08 31.7 0.2 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_4 PF13418.6 GAM25233.1 - 3.3e-32 110.2 23.3 4.1e-07 29.9 1.8 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM25233.1 - 8.4e-25 86.5 10.5 2.1e-07 31.1 0.1 6.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM25233.1 - 1.4e-23 81.9 12.8 5.3e-06 26.2 0.3 7.2 7 0 0 7 7 7 5 Kelch motif F-box-like PF12937.7 GAM25233.1 - 8.2e-08 32.0 0.1 1.6e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM25233.1 - 2.6e-05 24.0 0.5 5.3e-05 23.0 0.5 1.5 1 0 0 1 1 1 1 F-box domain Complex1_LYR PF05347.15 GAM25237.1 - 9.1e-13 48.1 0.2 1.5e-12 47.3 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) AA_permease_2 PF13520.6 GAM25238.1 - 5.9e-44 150.6 47.4 6.5e-44 150.4 46.4 1.5 1 1 0 1 1 1 1 Amino acid permease CLN3 PF02487.17 GAM25239.1 - 5.8e-64 216.6 11.8 6.7e-64 216.4 11.8 1.0 1 0 0 1 1 1 1 CLN3 protein S-AdoMet_synt_C PF02773.16 GAM25240.1 - 2.7e-66 221.8 0.1 1.2e-65 219.7 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GAM25240.1 - 4.3e-48 162.5 0.0 8e-48 161.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GAM25240.1 - 4.1e-45 152.5 0.5 9.3e-45 151.4 0.5 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain F-box PF00646.33 GAM25241.1 - 0.0048 16.7 0.2 0.017 15.0 0.2 1.9 1 0 0 1 1 1 1 F-box domain DUF5371 PF17341.2 GAM25241.1 - 0.1 12.8 0.3 0.35 11.1 0.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5371) F-box-like PF12937.7 GAM25241.1 - 0.11 12.4 0.4 0.31 11.0 0.4 1.7 1 0 0 1 1 1 0 F-box-like Secretin_N_2 PF07655.13 GAM25241.1 - 0.16 12.5 8.5 0.54 10.8 8.5 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain Bin3 PF06859.12 GAM25243.1 - 2.4e-36 124.6 0.0 2.4e-36 124.6 0.0 2.0 2 0 0 2 2 2 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 GAM25243.1 - 1.2e-11 45.1 0.0 0.00015 22.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAM25243.1 - 2.3e-11 44.2 0.0 2e-05 25.1 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 GAM25243.1 - 3.6e-10 39.9 0.0 4.4e-09 36.4 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM25243.1 - 8.2e-10 39.3 2.7 0.00032 21.4 0.0 3.6 4 0 0 4 4 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 GAM25243.1 - 4.7e-08 33.0 0.2 0.00037 20.3 0.1 2.6 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 GAM25243.1 - 9e-06 25.3 0.8 0.00099 18.7 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_18 PF12847.7 GAM25243.1 - 0.0026 17.7 0.1 0.0059 16.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pex14_N PF04695.13 GAM25243.1 - 0.0028 18.4 11.1 0.14 12.8 3.6 2.4 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region PrmA PF06325.13 GAM25243.1 - 0.0073 15.7 4.4 0.034 13.5 0.1 3.4 3 1 1 4 4 4 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 GAM25243.1 - 0.023 13.6 0.0 0.06 12.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) SR-25 PF10500.9 GAM25243.1 - 0.2 11.2 28.4 0.056 13.1 14.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Methyltransf_4 PF02390.17 GAM25243.1 - 0.25 10.8 4.6 0.26 10.7 0.0 2.8 3 0 0 3 3 3 0 Putative methyltransferase CCDC53 PF10152.9 GAM25243.1 - 0.94 9.9 14.2 0.38 11.2 7.4 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3408 PF11888.8 GAM25243.1 - 4.2 7.5 18.0 3.5 7.8 10.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Macoilin PF09726.9 GAM25243.1 - 4.6 5.7 22.5 3.3 6.1 2.8 2.1 2 0 0 2 2 2 0 Macoilin family SMYLE_N PF18615.1 GAM25243.1 - 6.2 6.3 16.0 0.98 8.9 8.6 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain FAM60A PF15396.6 GAM25243.1 - 6.4 6.7 15.6 3.4 7.6 8.4 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Hydin_ADK PF17213.3 GAM25243.1 - 7 6.9 17.1 1.7 8.9 6.4 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Tim54 PF11711.8 GAM25243.1 - 8.5 5.0 14.5 0.87 8.3 6.1 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Sulfate_transp PF00916.20 GAM25244.1 - 7.8e-97 324.4 28.2 7.8e-97 324.4 28.2 1.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 GAM25244.1 - 8.4e-17 60.9 0.0 1.7e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 GAM25244.1 - 3.5e-05 24.1 0.0 6.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAM25244.1 - 2.9 8.3 20.3 0.047 14.1 5.3 3.5 2 1 1 3 3 3 0 Molybdate transporter of MFS superfamily GBP PF02263.19 GAM25245.1 - 3.4e-43 147.8 0.1 5.7e-43 147.1 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 GAM25245.1 - 0.0008 19.5 0.2 0.0044 17.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF1800 PF08811.11 GAM25245.1 - 0.057 12.4 0.1 0.08 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Dynamin_N PF00350.23 GAM25245.1 - 0.065 13.3 0.9 0.55 10.3 0.0 2.7 3 1 0 3 3 3 0 Dynamin family SLAC1 PF03595.17 GAM25247.1 - 4.9e-23 81.9 39.0 6.7e-23 81.4 39.0 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel p450 PF00067.22 GAM25248.1 - 5.2e-84 282.6 0.0 5.8e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1295 PF06966.12 GAM25249.1 - 1.4e-38 132.8 5.4 1.6e-38 132.6 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 GAM25249.1 - 9.1e-06 25.7 1.7 2e-05 24.6 1.7 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 GAM25249.1 - 8.2e-05 22.9 2.2 0.00012 22.4 0.1 2.2 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 GAM25249.1 - 0.017 15.5 0.2 0.017 15.5 0.2 2.6 2 1 1 3 3 3 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 GAM25249.1 - 0.099 11.4 4.0 0.24 10.1 3.9 1.6 1 1 1 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family Lipase_3 PF01764.25 GAM25250.1 - 3.8e-25 88.4 0.0 5.3e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GAM25250.1 - 0.01 16.5 0.0 0.014 16.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 GAM25250.1 - 0.18 11.4 0.2 1.4 8.4 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Usp PF00582.26 GAM25251.1 - 5.9e-20 72.2 0.0 8.1e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family FTHFS PF01268.19 GAM25252.1 - 8.2e-261 866.0 0.0 9.2e-261 865.9 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 GAM25252.1 - 0.1 12.6 0.1 0.83 9.7 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Endotoxin_N PF03945.14 GAM25255.1 - 1.1e-34 120.1 4.0 1.9e-34 119.3 4.0 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain AA_permease_C PF13906.6 GAM25256.1 - 6.3e-08 32.6 3.4 7.2e-08 32.4 3.4 1.1 1 0 0 1 1 1 1 C-terminus of AA_permease YL1 PF05764.13 GAM25259.1 - 2.1e-06 28.0 12.5 2.2e-06 28.0 12.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 GAM25259.1 - 3.3e-05 22.4 13.5 3.4e-05 22.4 13.5 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 GAM25259.1 - 0.00065 18.1 17.6 0.0008 17.8 17.6 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 GAM25259.1 - 0.0011 18.5 18.6 0.0012 18.3 18.6 1.1 1 0 0 1 1 1 1 SDA1 Nop53 PF07767.11 GAM25259.1 - 0.0028 17.1 10.2 0.0036 16.8 10.2 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Utp14 PF04615.13 GAM25259.1 - 0.0033 16.1 10.3 0.0037 15.9 10.3 1.2 1 0 0 1 1 1 1 Utp14 protein HC2 PF07382.11 GAM25259.1 - 0.0051 16.9 10.4 0.0064 16.6 10.4 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Mpp10 PF04006.12 GAM25259.1 - 0.064 11.7 15.0 0.079 11.4 15.0 1.1 1 0 0 1 1 1 0 Mpp10 protein Apt1 PF10351.9 GAM25259.1 - 0.08 11.8 7.2 0.096 11.5 7.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sigma70_ner PF04546.13 GAM25259.1 - 0.32 10.9 16.8 0.46 10.3 16.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 GAM25259.1 - 0.35 8.9 29.5 0.43 8.6 29.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Lin-8 PF03353.15 GAM25259.1 - 0.44 10.1 4.0 0.43 10.1 4.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PI3K_1B_p101 PF10486.9 GAM25259.1 - 0.66 7.7 2.6 0.64 7.7 2.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 GAM25259.1 - 1.1 7.9 2.3 1.2 7.8 2.3 1.0 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GAM25259.1 - 2.3 7.5 27.6 3.1 7.1 27.6 1.1 1 0 0 1 1 1 0 BUD22 DUF4637 PF15470.6 GAM25259.1 - 2.7 7.7 8.4 4.2 7.1 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF913 PF06025.12 GAM25259.1 - 3 6.8 5.2 3.7 6.4 5.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CobT PF06213.12 GAM25259.1 - 3.4 7.0 20.0 4.5 6.6 20.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SGT1 PF07093.11 GAM25259.1 - 6 5.2 13.9 7.7 4.8 13.9 1.2 1 0 0 1 1 1 0 SGT1 protein eIF-3c_N PF05470.12 GAM25259.1 - 6.5 4.9 13.0 7.6 4.7 13.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRN3 PF05327.11 GAM25259.1 - 6.6 5.1 21.8 8.6 4.8 21.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFB6 PF17110.5 GAM25259.1 - 6.8 6.4 10.8 9.5 5.9 10.8 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Rad60-SLD PF11976.8 GAM25260.1 - 2.2e-05 24.2 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAM25260.1 - 9.1e-05 22.1 0.1 0.00063 19.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family TUG-UBL1 PF11470.8 GAM25260.1 - 0.0026 18.0 0.0 0.0053 17.0 0.0 1.6 1 1 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 GAM25260.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Raf-like Ras-binding domain Cobl PF09469.10 GAM25260.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain YukD PF08817.10 GAM25260.1 - 0.12 13.0 0.1 0.3 11.8 0.1 1.7 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD RasGEF PF00617.19 GAM25262.1 - 2e-40 138.9 0.3 6.8e-40 137.1 0.3 2.0 1 0 0 1 1 1 1 RasGEF domain RhoGAP PF00620.27 GAM25262.1 - 2.9e-11 43.4 0.1 2.9e-11 43.4 0.1 2.9 3 0 0 3 3 3 1 RhoGAP domain RasGEF_N PF00618.20 GAM25262.1 - 6.1e-08 32.8 0.2 2.5e-07 30.9 0.2 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF3915 PF13054.6 GAM25262.1 - 4 7.4 11.8 16 5.5 11.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Mon1 PF03164.14 GAM25264.1 - 4e-132 441.1 16.8 4.5e-132 440.9 16.8 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 FTCD_C PF04961.12 GAM25264.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase TFIIA PF03153.13 GAM25265.1 - 0.00071 19.7 21.5 0.00071 19.7 21.5 4.3 5 0 0 5 5 5 1 Transcription factor IIA, alpha/beta subunit SPO22 PF08631.10 GAM25265.1 - 0.021 14.3 0.2 0.021 14.3 0.2 3.8 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 GAM25265.1 - 0.038 14.3 6.3 11 6.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM25265.1 - 0.13 12.1 8.5 11 6.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Kdo PF06293.14 GAM25266.1 - 4.1e-14 52.4 0.0 3.6e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 GAM25266.1 - 2e-12 47.1 0.1 3.1e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25266.1 - 4.6e-09 35.9 0.1 7.4e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM25266.1 - 2.8e-08 34.0 0.0 0.0017 18.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 GAM25266.1 - 2.9e-07 30.3 0.0 5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.20 GAM25266.1 - 3.4e-05 23.3 0.2 0.00012 21.6 0.0 1.8 1 1 1 2 2 2 1 Ecdysteroid kinase YrbL-PhoP_reg PF10707.9 GAM25266.1 - 0.00067 19.2 0.6 0.0058 16.2 0.0 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 GAM25266.1 - 0.0088 15.6 0.1 0.033 13.8 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase C6 PF01681.17 GAM25266.1 - 0.019 15.5 3.4 0.019 15.5 3.4 1.7 2 0 0 2 2 2 0 C6 domain AA_permease_2 PF13520.6 GAM25267.1 - 5.5e-58 196.8 43.0 5.5e-58 196.8 43.0 2.0 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 GAM25267.1 - 3.2e-45 154.6 41.1 3.2e-45 154.6 41.1 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 GAM25267.1 - 1.3e-21 76.4 8.5 1.3e-21 76.4 8.5 3.9 4 0 0 4 4 4 1 C-terminus of AA_permease Spore_permease PF03845.13 GAM25267.1 - 1.1e-05 24.4 13.4 1.1e-05 24.4 13.4 3.2 2 2 0 2 2 2 1 Spore germination protein Auto_anti-p27 PF06677.12 GAM25268.1 - 2.3e-25 88.4 11.3 3.4e-14 52.7 2.4 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NRBF2 PF08961.10 GAM25268.1 - 0.00031 20.4 0.7 0.00031 20.4 0.7 3.0 3 1 0 3 3 3 2 Nuclear receptor-binding factor 2, autophagy regulator Ribosomal_S27e PF01667.17 GAM25268.1 - 0.016 14.9 2.1 0.052 13.3 2.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S27 PHD PF00628.29 GAM25268.1 - 4.6 7.2 9.0 3.9 7.4 2.1 2.7 2 0 0 2 2 2 0 PHD-finger EF-hand_7 PF13499.6 GAM25269.1 - 5.2e-21 74.9 8.9 1.6e-14 54.1 0.6 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 GAM25269.1 - 4.7e-18 63.3 6.2 6.1e-05 22.3 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 GAM25269.1 - 1.1e-15 56.1 1.8 0.00014 21.5 0.1 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 GAM25269.1 - 4.3e-13 48.9 5.3 2e-05 24.4 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 GAM25269.1 - 8.4e-12 44.0 4.2 0.0041 16.6 0.1 4.0 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 GAM25269.1 - 0.00026 21.3 0.1 0.94 9.9 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain TolA_bind_tri PF16331.5 GAM25269.1 - 0.0032 17.5 9.8 0.0032 17.5 9.8 8.8 3 1 5 8 8 7 1 TolA binding protein trimerisation EF-hand_4 PF12763.7 GAM25269.1 - 0.0054 16.7 1.7 0.095 12.7 0.1 3.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand APG6_N PF17675.1 GAM25269.1 - 0.015 15.8 14.8 0.015 15.8 14.8 6.1 3 2 3 6 6 6 0 Apg6 coiled-coil region Filament PF00038.21 GAM25269.1 - 0.034 13.7 87.7 0.022 14.4 42.4 4.3 1 1 2 3 3 3 0 Intermediate filament protein SPARC_Ca_bdg PF10591.9 GAM25269.1 - 0.62 10.4 0.0 0.62 10.4 0.0 6.1 5 2 1 6 6 6 0 Secreted protein acidic and rich in cysteine Ca binding region Spc7 PF08317.11 GAM25269.1 - 0.67 8.8 99.9 0.46 9.3 24.8 4.3 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF3410 PF11890.8 GAM25269.1 - 4.2 7.2 8.8 0.41 10.5 0.8 3.6 2 1 3 5 5 5 0 Domain of unknown function (DUF3410) PH PF00169.29 GAM25270.1 - 1.3e-13 51.3 0.0 4.4e-13 49.7 0.0 2.0 1 0 0 1 1 1 1 PH domain TIM21 PF08294.11 GAM25271.1 - 6.2e-08 32.6 0.4 7.9e-08 32.3 0.4 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 GAM25271.1 - 5.8e-07 29.3 0.1 1.4e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 BUD22 PF09073.10 GAM25272.1 - 0.67 9.2 42.8 2.1 7.6 17.1 2.1 2 0 0 2 2 2 0 BUD22 dCMP_cyt_deam_1 PF00383.23 GAM25273.1 - 3.1e-16 59.1 0.6 3.8e-16 58.8 0.6 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 GAM25273.1 - 1.1e-11 45.0 0.2 1.9e-09 37.8 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region PH PF00169.29 GAM25274.1 - 1.9e-26 92.6 2.9 7.9e-14 52.0 0.4 3.8 4 0 0 4 4 4 3 PH domain PH_11 PF15413.6 GAM25274.1 - 0.00016 22.1 7.8 0.32 11.5 0.4 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 GAM25274.1 - 0.045 14.1 2.6 0.2 12.0 0.2 3.0 3 1 0 3 3 3 0 Pleckstrin homology domain tRNA_int_endo PF01974.17 GAM25274.1 - 0.082 13.0 0.0 19 5.4 0.0 2.9 2 1 0 2 2 2 0 tRNA intron endonuclease, catalytic C-terminal domain FNIP PF05725.12 GAM25276.1 - 4.6e-34 116.3 13.9 3.2e-12 46.4 0.1 6.5 5 1 1 6 6 6 5 FNIP Repeat LRR_4 PF12799.7 GAM25276.1 - 0.015 15.7 13.8 1.9 9.1 0.0 5.8 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM25276.1 - 3 8.7 8.7 61 4.8 0.1 5.7 4 2 0 4 4 4 0 Leucine Rich Repeat DDE_Tnp_4 PF13359.6 GAM25277.1 - 2.3e-23 82.6 0.4 1.2e-21 77.1 0.3 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM25277.1 - 2.7e-08 33.7 1.9 4.7e-08 32.9 1.9 1.4 1 1 0 1 1 1 1 Transposase DDE domain GSHPx PF00255.19 GAM25278.1 - 0.00035 20.1 0.1 0.00059 19.4 0.1 1.4 1 1 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 GAM25279.1 - 0.0037 16.8 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase FNIP PF05725.12 GAM25280.1 - 2e-55 184.7 0.5 9e-14 51.4 0.1 7.6 5 2 1 7 7 7 7 FNIP Repeat DUF480 PF04337.12 GAM25280.1 - 0.13 12.4 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF480 Glyco_hydr_30_2 PF14587.6 GAM25281.1 - 1.4e-12 48.0 2.9 2.9e-12 46.9 2.9 1.5 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 ZapC PF07126.12 GAM25281.1 - 0.16 11.5 1.8 0.45 10.1 1.8 1.7 1 1 0 1 1 1 0 Cell-division protein ZapC DUF3435 PF11917.8 GAM25281.1 - 0.23 10.4 0.2 0.33 9.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) GSHPx PF00255.19 GAM25282.1 - 3.2e-21 74.9 0.3 4.1e-21 74.6 0.3 1.2 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 GAM25283.1 - 9.3e-27 92.7 0.2 1.2e-26 92.4 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Pkinase_Tyr PF07714.17 GAM25284.1 - 3.5e-63 213.3 0.0 5.4e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM25284.1 - 1.1e-46 159.4 0.0 2.4e-46 158.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 GAM25284.1 - 8.1e-07 28.6 0.0 1.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM25284.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_6 PF00970.24 GAM25286.1 - 9.6e-32 109.3 0.0 1.9e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAM25286.1 - 5.7e-31 107.4 0.0 9.8e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAM25286.1 - 4.3e-06 26.9 0.0 0.00012 22.3 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Sulfate_transp PF00916.20 GAM25287.1 - 4e-102 341.8 16.4 5.2e-102 341.4 16.4 1.1 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 GAM25287.1 - 0.019 15.4 3.6 0.019 15.4 3.6 3.1 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily IF-2B PF01008.17 GAM25288.1 - 8.9e-72 241.6 0.1 1e-71 241.5 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ERCC4 PF02732.15 GAM25290.1 - 3.1e-21 76.2 0.0 5.5e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain DHHC PF01529.20 GAM25291.1 - 1.3e-27 96.5 8.7 1.3e-27 96.5 8.7 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Presenilin PF01080.17 GAM25291.1 - 0.16 10.7 6.5 0.032 13.0 1.1 1.9 2 0 0 2 2 2 0 Presenilin 60KD_IMP PF02096.20 GAM25291.1 - 2.1 8.2 5.3 0.47 10.3 1.3 2.1 2 1 0 2 2 2 0 60Kd inner membrane protein NTP_transf_2 PF01909.23 GAM25292.1 - 2.7e-08 34.0 0.0 6.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 GAM25292.1 - 9.4e-07 28.9 0.1 5.1e-06 26.6 0.1 2.4 1 1 0 1 1 1 1 Cid1 family poly A polymerase AAA_23 PF13476.6 GAM25292.1 - 0.00057 20.4 5.3 0.00057 20.4 5.3 2.9 3 1 0 3 3 3 1 AAA domain Polbeta PF18765.1 GAM25292.1 - 0.029 14.5 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 GAM25292.1 - 0.088 13.0 0.5 0.66 10.2 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase beta palm WD40 PF00400.32 GAM25293.1 - 5.3e-12 46.1 11.1 0.013 16.3 0.6 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.6 GAM25293.1 - 0.00031 20.8 0.0 0.52 10.4 0.0 3.5 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Hira PF07569.11 GAM25293.1 - 0.015 15.0 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 GAM25293.1 - 0.018 15.3 0.0 22 5.4 0.0 4.0 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM25293.1 - 0.051 12.5 0.0 0.61 9.0 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein JAB PF01398.21 GAM25294.1 - 7.4e-09 35.6 0.0 7.4e-09 35.6 0.0 2.5 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 GAM25294.1 - 0.00042 20.1 0.4 0.0013 18.5 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Menin PF05053.13 GAM25294.1 - 3.4 5.9 13.4 5 5.4 13.4 1.3 1 0 0 1 1 1 0 Menin Asp-B-Hydro_N PF05279.11 GAM25294.1 - 4 7.5 9.2 5.3 7.0 9.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RhoGEF PF00621.20 GAM25296.1 - 7.9e-24 84.9 0.1 1.6e-23 83.9 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAM25296.1 - 0.0012 19.3 0.1 0.0035 17.8 0.1 1.8 1 0 0 1 1 1 1 PH domain DZR PF12773.7 GAM25296.1 - 0.0022 18.0 16.0 0.0058 16.6 16.0 1.8 1 0 0 1 1 1 1 Double zinc ribbon PH_13 PF16652.5 GAM25296.1 - 0.088 12.6 4.7 0.96 9.2 0.1 2.4 1 1 1 2 2 2 0 Pleckstrin homology domain zinc_ribbon_2 PF13240.6 GAM25296.1 - 3.1 7.6 8.4 1.4 8.7 5.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Metallophos PF00149.28 GAM25297.1 - 3.5e-21 76.6 0.7 6.3e-21 75.8 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 GAM25297.1 - 6e-18 65.2 1.0 1.4e-17 64.1 1.0 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 GAM25297.1 - 2e-08 35.0 0.0 6.8e-08 33.3 0.0 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 GAM25297.1 - 1.3e-06 28.7 0.0 9.8e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aldedh PF00171.22 GAM25298.1 - 7e-78 262.2 0.0 8.4e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAM25298.1 - 0.0049 16.3 0.0 0.0086 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) LMP PF04778.12 GAM25298.1 - 0.18 11.7 0.6 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 LMP repeated region HAP2-GCS1 PF10699.9 GAM25300.1 - 0.11 12.6 0.6 0.34 10.9 0.1 2.2 2 0 0 2 2 2 0 Male gamete fusion factor Mago-bind PF09282.10 GAM25301.1 - 1.7e-15 56.6 1.2 1.7e-15 56.6 1.2 1.7 2 0 0 2 2 2 1 Mago binding Anoctamin PF04547.12 GAM25301.1 - 0.26 10.1 0.1 0.35 9.7 0.1 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel PH PF00169.29 GAM25302.1 - 0.044 14.3 0.1 0.31 11.6 0.0 2.3 2 0 0 2 2 2 0 PH domain AAA_14 PF13173.6 GAM25302.1 - 0.12 12.4 0.1 4.6 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AvrPto PF11592.8 GAM25303.1 - 0.00012 22.0 0.1 0.00026 21.0 0.1 1.5 1 0 0 1 1 1 1 Central core of the bacterial effector protein AvrPto Ank_2 PF12796.7 GAM25303.1 - 0.00039 20.9 0.0 6.5 7.4 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) DUF3447 PF11929.8 GAM25303.1 - 0.002 18.1 0.1 1.6 8.7 0.1 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3447) Ost5 PF05251.12 GAM25304.1 - 1.8e-20 72.9 6.1 2e-20 72.8 6.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 CAAD PF14159.6 GAM25304.1 - 0.015 15.1 0.4 0.026 14.3 0.1 1.5 1 1 1 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PEP_mutase PF13714.6 GAM25305.1 - 7.7e-53 179.4 2.3 8.9e-53 179.2 2.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAM25305.1 - 3.1e-16 59.0 0.2 5.2e-16 58.2 0.2 1.3 1 0 0 1 1 1 1 Isocitrate lyase family Peptidase_C48 PF02902.19 GAM25306.1 - 6e-11 42.6 2.7 6e-11 42.6 2.7 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.19 GAM25307.1 - 2.4e-08 34.1 0.1 5.9e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SLS PF14611.6 GAM25307.1 - 0.13 12.1 1.7 0.21 11.4 1.7 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator YL1 PF05764.13 GAM25308.1 - 5.7e-06 26.6 12.4 6.7e-06 26.4 12.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein DUF4637 PF15470.6 GAM25308.1 - 0.05 13.3 4.2 0.065 13.0 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TT_ORF2 PF02957.15 GAM25308.1 - 0.098 13.6 3.6 0.15 13.0 3.6 1.3 1 0 0 1 1 1 0 TT viral ORF2 DNA_pol_phi PF04931.13 GAM25308.1 - 0.14 10.2 11.2 0.15 10.1 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GAM25308.1 - 0.15 10.2 8.1 0.15 10.3 8.1 1.0 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 GAM25308.1 - 1.7 8.3 5.8 1.9 8.1 5.8 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RRN3 PF05327.11 GAM25308.1 - 2.1 6.8 6.9 2.2 6.7 6.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pes-10 PF07149.11 GAM25308.1 - 2.4 7.1 8.2 2.5 7.1 8.2 1.1 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 GAM25308.1 - 2.9 6.1 9.7 3.4 5.8 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 GAM25308.1 - 3.5 6.7 13.2 4.4 6.4 13.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 GAM25308.1 - 4 6.7 9.6 4.4 6.6 9.6 1.1 1 0 0 1 1 1 0 NOA36 protein Sec6 PF06046.13 GAM25309.1 - 1.9e-119 399.7 5.8 2.6e-119 399.2 5.8 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF3629 PF12302.8 GAM25309.1 - 0.0077 15.7 0.5 0.031 13.7 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3629) RIH_assoc PF08454.11 GAM25309.1 - 0.11 12.4 2.3 1.1 9.1 2.3 2.7 1 1 0 1 1 1 0 RyR and IP3R Homology associated FAM167 PF11652.8 GAM25309.1 - 0.2 12.1 1.5 0.55 10.7 0.3 2.5 2 0 0 2 2 2 0 FAM167 OSCP PF00213.18 GAM25309.1 - 0.29 11.2 12.0 0.24 11.5 3.8 3.3 3 0 0 3 3 3 0 ATP synthase delta (OSCP) subunit Sec20 PF03908.13 GAM25309.1 - 0.48 10.4 3.2 1.2 9.1 0.1 3.1 2 1 1 3 3 3 0 Sec20 FlgN PF05130.12 GAM25309.1 - 0.52 10.8 5.1 0.73 10.3 0.2 2.6 2 0 0 2 2 2 0 FlgN protein FNIP PF05725.12 GAM25310.1 - 5.3e-15 55.3 19.6 6.9e-06 26.1 0.9 6.9 7 1 0 7 7 7 4 FNIP Repeat Arf PF00025.21 GAM25311.1 - 7.7e-66 220.8 0.2 8.7e-66 220.7 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAM25311.1 - 7.4e-16 58.2 0.1 8.2e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM25311.1 - 2.3e-15 56.9 0.1 3.5e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM25311.1 - 4.8e-15 55.5 0.0 5.5e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAM25311.1 - 1.3e-11 44.3 1.8 9.4e-09 34.9 0.2 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAM25311.1 - 2.5e-08 33.6 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM25311.1 - 1.8e-07 31.2 0.0 2.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 GAM25311.1 - 0.0027 17.5 0.2 0.068 13.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 GAM25311.1 - 0.0028 18.2 0.6 0.01 16.3 0.6 1.8 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 GAM25311.1 - 0.0042 17.0 0.1 2.9 7.8 0.2 2.1 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 GAM25311.1 - 0.0055 16.6 0.3 0.62 10.0 0.0 2.7 2 1 1 3 3 3 1 RsgA GTPase SRP54 PF00448.22 GAM25311.1 - 0.01 15.5 0.8 0.043 13.4 0.3 2.0 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.27 GAM25311.1 - 0.013 15.0 1.3 0.061 12.8 0.1 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA PF00004.29 GAM25311.1 - 0.047 14.1 0.0 0.069 13.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAM25311.1 - 0.056 13.6 0.2 0.093 12.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 GAM25311.1 - 0.084 12.6 0.2 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Vmethyltransf PF01660.17 GAM25311.1 - 0.11 11.4 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Viral methyltransferase AAA_18 PF13238.6 GAM25311.1 - 0.13 12.8 0.5 0.3 11.6 0.5 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 GAM25311.1 - 0.35 10.4 1.8 4.1 7.0 0.1 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4736 PF15883.5 GAM25312.1 - 0.026 14.3 1.5 0.036 13.8 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) DUF2570 PF10828.8 GAM25312.1 - 0.029 14.2 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) VirB3 PF05101.13 GAM25312.1 - 0.096 12.9 0.2 0.096 12.9 0.2 2.4 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein Pkinase PF00069.25 GAM25313.1 - 1.2e-62 211.7 1.3 1.8e-62 211.1 1.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25313.1 - 9.3e-41 139.8 1.0 1.4e-40 139.2 1.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM25313.1 - 0.00013 20.9 0.3 0.00042 19.2 0.2 1.8 1 1 1 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM25313.1 - 0.00015 20.8 0.2 0.00025 20.1 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM25313.1 - 0.0015 18.5 0.0 0.047 13.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM25313.1 - 0.0028 17.3 1.3 0.0059 16.2 1.3 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 GAM25313.1 - 0.0064 15.9 0.7 0.018 14.4 0.2 1.8 1 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family ADP_PFK_GK PF04587.15 GAM25313.1 - 0.0097 14.5 0.2 0.015 13.9 0.2 1.2 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region FTA2 PF13095.6 GAM25313.1 - 0.036 13.7 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 GAM25313.1 - 0.05 12.9 1.3 0.18 11.1 0.2 2.3 2 1 0 2 2 2 0 Kinase-like Abhydrolase_6 PF12697.7 GAM25314.1 - 8.6e-26 91.9 0.0 1e-25 91.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM25314.1 - 2.8e-09 36.6 0.1 3.8e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM25314.1 - 3.2e-07 30.2 1.8 9.3e-06 25.5 0.4 2.8 3 1 0 3 3 3 1 alpha/beta hydrolase fold PGAP1 PF07819.13 GAM25314.1 - 1.4e-05 25.0 0.2 2.1e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAM25314.1 - 0.0022 17.5 0.1 0.0035 16.9 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.16 GAM25314.1 - 0.027 14.3 2.0 2.6 7.8 2.0 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 GAM25314.1 - 0.063 12.2 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 GAM25314.1 - 0.073 12.9 0.3 0.15 11.9 0.3 1.5 1 1 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 GAM25314.1 - 0.1 12.4 1.6 0.31 10.9 1.6 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 GAM25314.1 - 0.12 12.2 2.5 7.7 6.3 0.5 2.4 1 1 0 2 2 2 0 Alpha/beta hydrolase family Thioesterase PF00975.20 GAM25314.1 - 0.16 12.0 0.1 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain MoCF_biosynth PF00994.24 GAM25315.1 - 3.5e-55 185.6 3.8 3.1e-27 95.0 0.1 3.4 3 1 0 3 3 3 2 Probable molybdopterin binding domain MoeA_N PF03453.17 GAM25315.1 - 1.2e-40 138.8 0.6 2.3e-40 137.9 0.6 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 GAM25315.1 - 2.8e-13 49.8 0.0 5.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) GRP PF07172.11 GAM25315.1 - 0.0028 18.3 1.0 0.0028 18.3 1.0 1.8 2 0 0 2 2 2 1 Glycine rich protein family Ligase_CoA PF00549.19 GAM25315.1 - 0.071 12.9 0.7 0.15 11.9 0.7 1.5 1 0 0 1 1 1 0 CoA-ligase SelP_N PF04592.14 GAM25315.1 - 8.7 5.7 9.2 16 4.8 9.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Glyco_hydro_18 PF00704.28 GAM25316.1 - 2.8e-26 93.0 0.2 3.6e-26 92.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Nas2_N PF18265.1 GAM25317.1 - 4.2e-21 74.6 0.0 6e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 GAM25317.1 - 3.6e-07 30.4 0.1 1.2e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 GAM25317.1 - 6.8e-05 22.6 0.0 0.00069 19.4 0.0 2.4 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 GAM25317.1 - 0.00063 20.0 0.1 0.002 18.5 0.0 1.8 1 1 0 1 1 1 1 PDZ domain Hamartin PF04388.12 GAM25317.1 - 0.0089 14.7 2.7 0.0088 14.8 2.7 1.1 1 0 0 1 1 1 1 Hamartin protein DUF2057 PF09829.9 GAM25317.1 - 0.034 14.3 1.6 0.052 13.7 1.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) GRASP55_65 PF04495.14 GAM25317.1 - 0.071 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain CCDC24 PF15669.5 GAM25317.1 - 0.077 12.9 0.3 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DpnII-MboI PF18742.1 GAM25317.1 - 0.19 11.4 0.0 17 5.0 0.0 2.2 2 0 0 2 2 2 0 REase_DpnII-MboI DUF908 PF06012.12 GAM25317.1 - 0.21 10.9 3.6 0.28 10.5 3.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Herpes_pp85 PF04637.12 GAM25317.1 - 0.62 8.4 1.8 0.78 8.1 1.8 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) KIAA1328 PF15369.6 GAM25317.1 - 0.92 9.3 4.7 0.92 9.3 0.5 2.0 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 Bromodomain PF00439.25 GAM25318.1 - 5.8e-07 29.5 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain FHA PF00498.26 GAM25318.1 - 0.02 15.2 0.1 0.042 14.2 0.1 1.6 1 0 0 1 1 1 0 FHA domain Peptidase_M17 PF00883.21 GAM25319.1 - 2.3e-122 408.2 0.1 3e-122 407.8 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 GAM25319.1 - 8.3e-20 70.9 0.1 1.8e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain PDZ_2 PF13180.6 GAM25319.1 - 0.041 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Dec-1 PF04624.14 GAM25319.1 - 0.21 11.5 0.8 0.38 10.7 0.8 1.3 1 0 0 1 1 1 0 Dec-1 repeat LSM PF01423.22 GAM25320.1 - 1.9e-17 62.7 0.4 3.3e-17 61.9 0.4 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM25320.1 - 0.057 13.6 0.2 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 Ataxin 2 SM domain Hfq PF17209.3 GAM25320.1 - 0.094 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Hfq protein NAGLU_N PF12971.7 GAM25322.1 - 0.17 11.7 0.8 0.26 11.1 0.7 1.4 1 1 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF4537 PF15057.6 GAM25324.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Agenet PF05641.12 GAM25324.1 - 0.062 13.8 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 0 Agenet domain TraT PF05818.12 GAM25326.1 - 0.068 12.8 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DDE_1 PF03184.19 GAM25329.1 - 0.0037 17.0 0.0 0.0044 16.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-L PF13092.6 GAM25329.1 - 0.045 14.0 0.0 0.059 13.6 0.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 DDE_3 PF13358.6 GAM25329.1 - 0.048 13.4 0.1 0.051 13.3 0.1 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 GAM25330.1 - 2.2e-05 24.4 0.2 6.6e-05 22.9 0.1 1.8 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain Transglut_core2 PF13369.6 GAM25330.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily GCR1_C PF12550.8 GAM25331.1 - 0.00098 19.4 0.4 0.0022 18.3 0.4 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TraT PF05818.12 GAM25332.1 - 0.017 14.8 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein OPT PF03169.15 GAM25333.1 - 8.9e-126 421.0 33.2 1.1e-125 420.7 33.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4535 PF15054.6 GAM25333.1 - 0.027 14.2 0.1 0.063 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) DUF3093 PF11292.8 GAM25333.1 - 8.2 6.7 9.1 0.87 9.8 2.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) DUF1699 PF08004.11 GAM25334.1 - 0.082 12.6 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) TIG PF01833.24 GAM25335.1 - 4.6e-14 52.3 21.3 1e-07 31.9 1.5 4.3 3 0 0 3 3 3 3 IPT/TIG domain EGF_2 PF07974.13 GAM25335.1 - 3.4e-05 24.1 10.1 9.6e-05 22.7 10.1 1.8 1 0 0 1 1 1 1 EGF-like domain SKG6 PF08693.10 GAM25335.1 - 0.0094 15.3 0.7 0.024 14.1 0.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_4 PF12799.7 GAM25335.1 - 0.017 15.5 1.4 0.017 15.5 1.4 4.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) EGF_Tenascin PF18720.1 GAM25335.1 - 0.091 12.8 8.4 0.19 11.8 8.4 1.6 1 0 0 1 1 1 0 Tenascin EGF domain LRR_8 PF13855.6 GAM25335.1 - 0.12 12.1 6.5 0.22 11.3 3.5 2.9 2 1 1 3 3 3 0 Leucine rich repeat EGF PF00008.27 GAM25335.1 - 0.14 12.5 7.8 0.34 11.3 7.8 1.6 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 GAM25335.1 - 0.2 11.8 5.7 0.71 10.1 5.7 1.9 1 0 0 1 1 1 0 Laminin EGF domain hEGF PF12661.7 GAM25335.1 - 0.4 11.4 5.0 1.4 9.7 5.0 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF SlyX PF04102.12 GAM25336.1 - 0.0022 18.6 1.2 0.0046 17.6 1.2 1.5 1 0 0 1 1 1 1 SlyX Cpn60_TCP1 PF00118.24 GAM25337.1 - 3.2e-105 352.6 0.1 4e-105 352.3 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3439 PF11921.8 GAM25338.1 - 0.037 14.0 2.3 0.096 12.7 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAM25338.1 - 3.1 7.8 14.8 2.8 7.9 13.1 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Rib_5-P_isom_A PF06026.14 GAM25339.1 - 1.4e-63 213.6 0.1 1.8e-63 213.3 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 GAM25339.1 - 0.02 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain DeoRC PF00455.22 GAM25339.1 - 0.058 13.3 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Ank_3 PF13606.6 GAM25340.1 - 0.032 14.8 2.4 24 5.9 0.0 5.1 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 GAM25340.1 - 1.1 9.9 4.4 1.5e+02 3.1 0.0 5.2 5 2 2 7 7 7 0 Ankyrin repeats (many copies) TAD2 PF18521.1 GAM25340.1 - 4.3 7.5 4.7 1.5 8.9 0.5 2.5 3 0 0 3 3 3 0 Transactivation domain 2 Arrestin_N PF00339.29 GAM25341.1 - 1.7e-18 67.1 3.4 1.6e-13 50.9 0.1 3.3 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain FYVE PF01363.21 GAM25341.1 - 4.6e-18 65.1 15.3 8.4e-18 64.3 15.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger Arrestin_C PF02752.22 GAM25341.1 - 3e-17 63.3 0.8 3.1e-13 50.4 0.4 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 GAM25341.1 - 4.1e-06 26.2 1.8 0.0049 16.1 0.1 3.0 2 1 1 3 3 3 2 Rgp1 Raco_middle PF17651.1 GAM25341.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 RACo middle region FYVE_2 PF02318.16 GAM25341.1 - 0.068 13.4 9.7 0.17 12.1 9.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Lar_restr_allev PF14354.6 GAM25341.1 - 0.75 10.2 9.4 5.8 7.4 9.4 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-FCS PF06467.14 GAM25341.1 - 6 6.9 14.0 15 5.6 14.0 1.7 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Myosin_head PF00063.21 GAM25342.1 - 4.1e-249 828.4 2.1 5.1e-249 828.0 2.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAM25342.1 - 3e-38 131.4 1.1 5.2e-38 130.6 1.1 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 GAM25342.1 - 5e-18 64.4 0.3 1.4e-17 63.0 0.2 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 GAM25342.1 - 1.9e-16 59.6 0.0 4.8e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM25342.1 - 3.2e-12 45.9 0.0 7.6e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Phage_int_SAM_3 PF14659.6 GAM25342.1 - 0.0036 17.6 0.8 0.011 15.9 0.8 1.9 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain AAA_22 PF13401.6 GAM25342.1 - 0.032 14.5 0.1 0.15 12.3 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 GAM25342.1 - 0.037 14.4 0.0 0.086 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 GAM25342.1 - 0.059 13.8 0.4 0.36 11.2 0.0 2.6 3 0 0 3 3 2 0 RNA helicase NACHT PF05729.12 GAM25342.1 - 0.073 13.0 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 GAM25342.1 - 0.085 12.1 0.8 0.21 10.9 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 GAM25342.1 - 0.09 12.5 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 GAM25342.1 - 0.13 11.2 0.0 0.28 10.1 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FNIP PF05725.12 GAM25343.1 - 5.9e-40 135.2 23.5 1.5e-14 53.9 0.3 5.0 5 0 0 5 5 5 4 FNIP Repeat FNIP PF05725.12 GAM25345.1 - 2.9e-78 257.8 26.5 4.1e-13 49.3 0.0 7.2 4 1 1 7 7 7 7 FNIP Repeat LRR_8 PF13855.6 GAM25345.1 - 0.01 15.6 3.1 5.9 6.7 0.1 4.2 4 1 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 GAM25345.1 - 0.37 11.5 8.3 17 6.5 0.3 5.7 5 1 0 5 5 5 0 Leucine Rich Repeat FNIP PF05725.12 GAM25346.1 - 6.9e-105 343.0 24.3 6.9e-14 51.7 0.5 7.8 2 1 9 11 11 11 11 FNIP Repeat LRR_5 PF13306.6 GAM25346.1 - 0.00018 21.5 0.1 5.1 7.1 0.0 3.8 2 1 3 5 5 4 4 BspA type Leucine rich repeat region (6 copies) zf-CCHH PF10283.9 GAM25347.1 - 6.2e-06 26.1 0.8 1.4e-05 25.0 0.8 1.7 1 0 0 1 1 1 1 PBZ domain EGF_2 PF07974.13 GAM25348.1 - 0.0005 20.4 29.6 0.088 13.2 9.9 2.7 2 0 0 2 2 2 2 EGF-like domain SKG6 PF08693.10 GAM25348.1 - 0.68 9.4 4.4 1.5 8.3 4.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TIG PF01833.24 GAM25348.1 - 2.7 8.1 12.1 1.9 8.6 0.0 5.3 5 0 0 5 5 5 0 IPT/TIG domain hEGF PF12661.7 GAM25348.1 - 9.6 7.0 13.4 5.1 7.9 5.4 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.13 GAM25350.1 - 0.0013 19.0 28.0 0.019 15.3 10.6 2.6 2 0 0 2 2 2 2 EGF-like domain DUF3377 PF11857.8 GAM25350.1 - 0.07 13.1 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) EGF PF00008.27 GAM25350.1 - 2.5 8.5 17.7 0.92 9.9 7.3 2.7 2 0 0 2 2 2 0 EGF-like domain SKG6 PF08693.10 GAM25350.1 - 3.4 7.1 9.5 2.4 7.6 6.1 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Ank_5 PF13857.6 GAM25351.1 - 2.2e-19 69.2 1.3 3.2e-10 40.0 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM25351.1 - 6.6e-18 64.8 1.4 6.7e-13 48.9 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM25351.1 - 1.1e-14 54.7 1.2 4e-14 53.0 1.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAM25351.1 - 1.4e-14 53.8 0.4 8.3e-07 29.2 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 GAM25351.1 - 1.3e-10 40.5 0.1 0.00052 20.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat HMG-CoA_red PF00368.18 GAM25352.1 - 3.7e-153 509.9 1.1 4.4e-153 509.6 1.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase PH PF00169.29 GAM25353.1 - 2.4e-05 24.8 0.7 0.00014 22.3 0.2 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 GAM25353.1 - 3.6 8.1 6.4 5 7.6 0.7 3.2 2 1 1 3 3 3 0 Pleckstrin homology domain Mpv17_PMP22 PF04117.12 GAM25355.1 - 7.3e-14 51.7 4.6 7.5e-14 51.7 2.7 2.0 1 1 1 2 2 2 1 Mpv17 / PMP22 family TauE PF01925.19 GAM25355.1 - 0.0099 15.5 0.5 0.013 15.2 0.3 1.4 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE CNOT1_TTP_bind PF16417.5 GAM25355.1 - 0.082 12.1 0.2 0.21 10.7 0.1 1.6 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 TTP binding domain UQ_con PF00179.26 GAM25357.1 - 2.3e-51 173.1 0.0 2.6e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM25357.1 - 0.0007 19.3 0.0 0.00081 19.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAM25357.1 - 0.0027 18.0 0.4 0.0062 16.8 0.4 1.6 1 1 0 1 1 1 1 RWD domain FNIP PF05725.12 GAM25358.1 - 1.8e-64 213.6 29.4 8.2e-11 41.9 0.1 10.9 7 3 2 11 11 11 10 FNIP Repeat CbiQ PF02361.16 GAM25359.1 - 0.079 12.6 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Cobalt transport protein DNA_pol_E_B PF04042.16 GAM25360.1 - 2.9e-36 124.8 0.2 5.1e-36 124.0 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 GAM25360.1 - 2.6e-34 118.1 0.0 1.1e-33 116.1 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain DUF4811 PF16069.5 GAM25360.1 - 0.042 13.7 6.4 0.083 12.8 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) Menin PF05053.13 GAM25360.1 - 2 6.6 7.0 2.9 6.1 7.0 1.1 1 0 0 1 1 1 0 Menin ARPC4 PF05856.12 GAM25362.1 - 4.9e-76 254.0 7.6 5.8e-76 253.8 7.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) SUI1 PF01253.22 GAM25363.1 - 7.5e-22 77.7 0.2 1.5e-21 76.7 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Dicty_REP PF05086.12 GAM25363.1 - 0.069 11.1 7.5 0.072 11.1 7.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UreE_N PF02814.15 GAM25363.1 - 0.081 12.5 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain DUF966 PF06136.13 GAM25363.1 - 0.35 10.6 6.2 0.41 10.3 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.17 GAM25363.1 - 1.1 7.9 3.1 1.4 7.6 3.1 1.1 1 0 0 1 1 1 0 Presenilin Mucin PF01456.17 GAM25363.1 - 1.9 8.5 27.2 0.54 10.2 24.3 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein LMBR1 PF04791.16 GAM25364.1 - 8.3e-111 371.4 18.6 1e-110 371.1 18.6 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Hrs_helical PF12210.8 GAM25364.1 - 0.11 13.1 0.1 0.26 11.9 0.1 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Pkinase_Tyr PF07714.17 GAM25365.1 - 9.5e-63 211.9 0.0 3.6e-62 210.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GAM25365.1 - 3.6e-52 177.4 0.0 1e-51 175.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 GAM25365.1 - 7.2e-18 64.1 29.7 1.5e-10 40.7 8.6 3.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 GAM25365.1 - 3.7e-14 52.6 29.5 1.3e-05 25.4 5.7 5.3 3 1 3 6 6 5 5 Leucine Rich repeats (2 copies) APH PF01636.23 GAM25365.1 - 0.00011 22.2 0.5 0.00043 20.3 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family LRR_1 PF00560.33 GAM25365.1 - 0.00039 20.6 12.3 24 6.0 0.1 7.3 6 0 0 6 6 6 0 Leucine Rich Repeat Kinase-like PF14531.6 GAM25365.1 - 0.001 18.5 0.0 0.003 16.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like LRR_9 PF14580.6 GAM25365.1 - 0.0023 17.5 3.0 0.0054 16.3 3.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat DUF4571 PF15137.6 GAM25365.1 - 0.11 12.2 1.9 0.31 10.7 1.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4571) DUF724 PF05266.14 GAM25365.1 - 0.16 11.8 3.1 0.36 10.6 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4337 PF14235.6 GAM25365.1 - 0.61 10.2 5.3 1.3 9.1 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) LRR_6 PF13516.6 GAM25365.1 - 4.1 7.7 19.0 1.4 9.1 0.3 5.6 5 0 0 5 5 5 0 Leucine Rich repeat zf-CCCH_4 PF18044.1 GAM25366.1 - 8.1e-19 67.0 32.7 7.7e-05 22.4 1.7 4.6 4 0 0 4 4 4 4 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAM25366.1 - 1.7e-16 59.7 43.0 2e-05 24.5 4.6 4.9 4 1 0 4 4 4 4 Zinc finger domain zf-CCCH PF00642.24 GAM25366.1 - 3.6e-16 58.6 26.3 7.8e-05 22.5 1.2 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAM25366.1 - 6.9e-13 49.3 36.1 4.8e-05 24.0 2.1 5.6 4 1 2 6 6 4 4 Torus domain zf-CCCH_2 PF14608.6 GAM25366.1 - 2.1e-09 37.5 35.2 0.0022 18.4 4.6 4.7 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-C3HC4 PF00097.25 GAM25366.1 - 8.9e-08 31.9 3.9 3.9e-07 29.8 3.9 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM25366.1 - 3.9e-07 30.3 4.9 3.9e-07 30.3 4.9 3.0 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 GAM25366.1 - 6.5e-07 29.2 3.9 2.3e-06 27.4 3.9 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAM25366.1 - 0.0004 20.3 4.5 0.0013 18.7 4.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_3 PF15663.5 GAM25366.1 - 0.00055 20.1 12.1 0.44 10.8 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger containing family zf-RING_11 PF17123.5 GAM25366.1 - 0.0054 16.5 7.4 0.013 15.2 7.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAM25366.1 - 0.019 14.8 1.6 0.019 14.8 1.6 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM25366.1 - 0.078 12.9 6.8 1.5 8.7 6.8 2.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 GAM25366.1 - 0.095 12.6 0.8 0.3 11.0 0.8 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GAM25366.1 - 0.73 10.2 12.0 0.15 12.4 6.1 3.1 2 1 0 2 2 2 0 RING-H2 zinc finger domain USP19_linker PF16602.5 GAM25366.1 - 1.5 9.4 6.6 0.32 11.6 1.7 2.3 2 0 0 2 2 2 0 Linker region of USP19 deubiquitinase zf-C3HC4_4 PF15227.6 GAM25366.1 - 1.5 9.0 8.6 0.5 10.6 3.6 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING GIT_CC PF16559.5 GAM25367.1 - 0.0022 17.8 0.7 0.0022 17.8 0.7 2.2 3 0 0 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor Cwf_Cwc_15 PF04889.12 GAM25367.1 - 0.0052 16.6 10.2 0.0052 16.6 10.2 1.7 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 GAM25367.1 - 4.7 7.3 16.0 0.25 11.4 7.9 2.3 1 1 1 2 2 2 0 YL1 nuclear protein FAM76 PF16046.5 GAM25367.1 - 7.6 5.8 10.0 2 7.7 6.2 1.8 1 1 1 2 2 2 0 FAM76 protein Med3 PF11593.8 GAM25368.1 - 0.014 14.6 12.2 0.018 14.2 12.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AF-4 PF05110.13 GAM25368.1 - 0.088 10.9 26.7 0.13 10.3 26.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Dicty_REP PF05086.12 GAM25368.1 - 0.11 10.5 10.7 0.12 10.3 10.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RR_TM4-6 PF06459.12 GAM25368.1 - 0.92 9.3 12.6 1.2 8.9 12.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOBP PF15279.6 GAM25368.1 - 1.3 9.6 13.3 1.8 9.1 13.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.9 GAM25368.1 - 4.1 5.9 14.6 5.5 5.4 14.6 1.1 1 0 0 1 1 1 0 Macoilin family KIAA1328 PF15369.6 GAM25368.1 - 4.8 6.9 11.3 6.1 6.6 11.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 RAP1 PF07218.11 GAM25368.1 - 7.7 4.7 14.4 9 4.4 14.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GREB1 PF15782.5 GAM25368.1 - 8.6 3.3 13.0 10 3.1 13.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4551 PF15087.6 GAM25368.1 - 9.2 5.0 12.9 11 4.7 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TPR_17 PF13431.6 GAM25369.1 - 0.031 14.6 0.2 0.37 11.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1084 PF06454.11 GAM25371.1 - 2.5e-07 30.4 31.2 7.7e-07 28.8 31.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) UAA PF08449.11 GAM25374.1 - 1.8e-91 306.5 26.0 2.3e-91 306.1 26.0 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 GAM25374.1 - 6.2e-07 29.1 24.6 8.9e-06 25.2 5.3 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 GAM25374.1 - 3.6e-06 27.2 39.4 0.0062 16.7 8.6 3.3 2 2 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 GAM25374.1 - 0.022 14.0 28.4 0.099 11.8 28.4 2.1 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Beta_helix PF13229.6 GAM25375.1 - 4e-10 39.8 59.4 4.8e-06 26.5 18.4 4.0 1 1 2 3 3 3 3 Right handed beta helix region NosD PF05048.13 GAM25375.1 - 0.97 8.7 59.1 0.16 11.2 19.6 4.4 1 1 2 4 4 4 0 Periplasmic copper-binding protein (NosD) Cnd1 PF12717.7 GAM25376.1 - 3.2e-07 30.5 2.5 3.2e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM25376.1 - 0.00028 21.2 0.0 0.011 16.1 0.0 2.6 2 2 0 2 2 2 1 HEAT repeats HEAT PF02985.22 GAM25376.1 - 0.00032 20.7 0.0 0.29 11.5 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat DUF1902 PF08972.11 GAM25376.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) CBS PF00571.28 GAM25377.1 - 3.3e-29 101.1 1.3 1.6e-13 50.8 0.2 2.1 2 0 0 2 2 2 2 CBS domain PRC PF05239.16 GAM25377.1 - 0.042 13.9 0.0 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 PRC-barrel domain Thioredoxin_7 PF13899.6 GAM25378.1 - 3.1e-12 46.5 0.0 6.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 GAM25378.1 - 5e-12 45.8 0.1 1.5e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 GAM25378.1 - 6.6e-10 38.6 0.1 1.7e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_2 PF13098.6 GAM25378.1 - 0.0029 18.0 0.0 0.0062 17.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain PPP4R2 PF09184.11 GAM25378.1 - 0.006 16.2 17.4 0.011 15.4 17.4 1.4 1 0 0 1 1 1 1 PPP4R2 SAPS PF04499.15 GAM25378.1 - 0.0093 14.8 2.7 0.012 14.5 2.7 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein RNA_pol_3_Rpc31 PF11705.8 GAM25378.1 - 0.013 15.8 14.2 0.026 14.8 14.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CAF1-p150_C2 PF15539.6 GAM25378.1 - 0.04 13.4 7.4 0.077 12.5 7.4 1.4 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term TFIIA PF03153.13 GAM25378.1 - 0.061 13.3 16.5 0.094 12.7 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 GAM25378.1 - 0.081 11.7 0.3 0.16 10.7 0.3 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Myc_N PF01056.18 GAM25378.1 - 0.088 12.7 6.7 0.18 11.7 6.7 1.5 1 0 0 1 1 1 0 Myc amino-terminal region DUF913 PF06025.12 GAM25378.1 - 0.095 11.7 1.3 0.15 11.0 1.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GAM25378.1 - 0.18 10.6 1.9 0.24 10.2 1.9 1.2 1 0 0 1 1 1 0 Presenilin ORC6 PF05460.13 GAM25378.1 - 0.19 11.0 7.4 0.29 10.4 7.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) BUD22 PF09073.10 GAM25378.1 - 0.23 10.8 15.2 0.44 9.8 15.2 1.4 1 0 0 1 1 1 0 BUD22 Nucleo_P87 PF07267.11 GAM25378.1 - 0.27 10.0 8.2 0.4 9.5 8.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3295 PF11702.8 GAM25378.1 - 0.43 9.9 16.9 0.68 9.2 16.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Menin PF05053.13 GAM25378.1 - 0.72 8.2 6.0 1.1 7.5 6.0 1.2 1 0 0 1 1 1 0 Menin DNA_pol_phi PF04931.13 GAM25378.1 - 1.3 7.0 20.2 2 6.4 20.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 GAM25378.1 - 3.8 7.2 23.2 7.2 6.3 23.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAM25378.1 - 5 6.4 29.0 0.032 13.6 20.7 1.5 2 0 0 2 2 1 0 NOA36 protein DUF4746 PF15928.5 GAM25378.1 - 8.5 5.7 9.0 19 4.6 9.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF5403 PF17395.2 GAM25379.1 - 0.027 14.7 0.0 0.063 13.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5403) Striatin PF08232.12 GAM25379.1 - 2.8 8.5 30.4 0.072 13.7 1.8 3.5 3 0 0 3 3 3 0 Striatin family PepSY_TM PF03929.16 GAM25379.1 - 7 6.2 7.3 2.9 7.5 0.2 2.4 3 0 0 3 3 3 0 PepSY-associated TM region PHD PF00628.29 GAM25380.1 - 1e-05 25.3 19.7 3.6e-05 23.6 7.7 3.1 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.6 GAM25380.1 - 0.02 14.4 9.3 0.024 14.2 5.5 2.8 1 1 1 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 GAM25380.1 - 1.5 8.4 16.0 0.17 11.5 1.0 3.1 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Diphthamide_syn PF01866.17 GAM25381.1 - 1.7e-85 287.1 2.7 1.2e-84 284.4 2.7 1.9 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Menin PF05053.13 GAM25381.1 - 1.5 7.1 4.6 0.76 8.1 0.4 2.1 2 0 0 2 2 2 0 Menin COPI_assoc PF08507.10 GAM25382.1 - 1.1e-18 67.6 7.2 1.4e-18 67.1 7.2 1.1 1 0 0 1 1 1 1 COPI associated protein PelG PF16933.5 GAM25382.1 - 0.54 9.1 13.7 0.69 8.7 13.7 1.0 1 0 0 1 1 1 0 Putative exopolysaccharide Exporter (EPS-E) MAGE PF01454.19 GAM25383.1 - 4.6e-29 101.6 0.1 1.3e-28 100.2 0.1 1.7 1 1 0 1 1 1 1 MAGE family SCP2 PF02036.17 GAM25384.1 - 1.2e-53 179.8 2.9 9.7e-27 93.4 0.4 2.1 2 0 0 2 2 2 2 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 GAM25384.1 - 4.5e-12 46.3 0.2 5.1e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal Ribosomal_60s PF00428.19 GAM25384.1 - 0.052 14.1 2.8 0.14 12.8 2.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Y_Y_Y PF07495.13 GAM25385.1 - 0.00041 20.2 8.5 1.9 8.5 0.1 5.4 6 0 0 6 6 6 2 Y_Y_Y domain DUF2012 PF09430.10 GAM25385.1 - 0.0015 18.6 0.2 11 6.2 0.1 3.8 2 1 2 4 4 4 2 Protein of unknown function (DUF2012) TcfC PF16967.5 GAM25385.1 - 0.0067 15.9 0.1 1.2 8.7 0.0 3.4 3 0 0 3 3 3 1 E-set like domain SpaA PF17802.1 GAM25385.1 - 0.16 12.3 2.0 31 5.0 1.3 3.7 2 1 1 3 3 3 0 Prealbumin-like fold domain SprB PF13573.6 GAM25385.1 - 1.2 8.9 8.2 1.7 8.5 1.1 3.5 3 0 0 3 3 3 0 SprB repeat Acetyltransf_1 PF00583.25 GAM25386.1 - 2.5e-15 56.8 0.0 3.1e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM25386.1 - 4.7e-14 52.4 0.0 6.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM25386.1 - 5.8e-11 42.7 0.0 8.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAM25386.1 - 6.1e-06 26.3 0.0 7.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM25386.1 - 0.0017 18.5 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM25386.1 - 0.0023 17.9 0.0 0.0059 16.5 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein PanZ PF12568.8 GAM25386.1 - 0.016 14.9 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 GAM25386.1 - 0.025 14.1 0.3 0.03 13.8 0.3 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase EF-hand_7 PF13499.6 GAM25387.1 - 2.7e-09 37.3 0.0 3.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAM25387.1 - 7.7e-09 34.5 0.0 0.00041 19.7 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 GAM25387.1 - 8.1e-09 34.7 0.0 0.00025 20.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAM25387.1 - 3.7e-08 33.1 0.1 0.00028 20.7 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM25387.1 - 0.0083 15.6 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 2 EF hand Cu-binding_MopE PF11617.8 GAM25387.1 - 0.2 11.9 3.8 1.9 8.8 0.2 2.9 2 0 0 2 2 2 0 Putative metal-binding motif EF-hand_10 PF14788.6 GAM25387.1 - 0.24 11.3 0.4 0.4 10.6 0.3 1.3 1 1 0 1 1 1 0 EF hand Ribosomal_L14 PF00238.19 GAM25388.1 - 1.4e-30 105.9 0.1 1.6e-30 105.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e MRP-L46 PF11788.8 GAM25389.1 - 0.00081 20.1 1.4 0.00081 20.1 1.4 2.6 2 2 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Adaptin_binding PF10199.9 GAM25389.1 - 0.028 15.0 1.9 8 7.1 0.2 2.6 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 NUDIX PF00293.28 GAM25389.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain Na_H_Exchanger PF00999.21 GAM25390.1 - 3.3e-55 187.4 45.1 4.2e-55 187.1 45.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.12 GAM25390.1 - 0.0001 22.2 9.7 0.0001 22.2 9.7 2.9 3 0 0 3 3 3 1 Predicted Permease Membrane Region RRM_1 PF00076.22 GAM25391.1 - 1.9e-43 146.1 2.3 1.3e-13 50.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM25391.1 - 0.00025 21.1 0.3 1.4 9.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 GAM25391.1 - 0.0056 16.7 1.6 6 7.0 0.2 3.3 3 0 0 3 3 3 2 RNA binding motif PHM7_cyt PF14703.6 GAM25391.1 - 0.022 15.0 0.8 0.34 11.1 0.1 2.9 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Glutaredoxin PF00462.24 GAM25392.1 - 5.7e-18 64.9 0.0 9.6e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 GAM25392.1 - 0.021 15.0 0.0 0.039 14.1 0.0 1.6 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein TPR_1 PF00515.28 GAM25393.1 - 1.1e-12 47.1 6.4 6.5e-05 22.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAM25393.1 - 1.3e-11 43.7 2.9 0.00015 21.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM25393.1 - 1.9e-07 31.4 1.3 1.9e-07 31.4 1.3 3.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM25393.1 - 1.8e-06 28.5 0.0 5.8e-06 26.9 0.0 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM25393.1 - 5.5e-06 26.5 3.3 3e-05 24.2 3.2 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.9 GAM25393.1 - 1.5e-05 23.9 1.3 3.6e-05 22.7 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Coatomer_E PF04733.14 GAM25393.1 - 9.4e-05 22.0 5.9 0.077 12.4 0.6 2.5 1 1 1 2 2 2 2 Coatomer epsilon subunit TPR_8 PF13181.6 GAM25393.1 - 0.0001 22.2 7.9 0.19 12.0 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM25393.1 - 0.00074 19.6 0.1 0.0034 17.5 0.2 2.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM25393.1 - 0.00094 19.4 3.6 0.096 13.0 0.2 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM25393.1 - 0.002 18.6 4.6 1.7 9.4 0.1 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM25393.1 - 0.024 15.4 0.4 5.4 8.1 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM25393.1 - 0.035 14.1 1.6 1.7 8.8 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM25393.1 - 0.068 12.9 6.6 4.7 7.0 0.1 3.6 3 0 0 3 3 3 0 TPR repeat TPR_17 PF13431.6 GAM25393.1 - 0.072 13.5 4.2 24 5.6 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM25393.1 - 0.18 11.7 1.9 1.9 8.5 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 GAM25393.1 - 2.4 8.3 7.0 2.8 8.1 0.3 3.5 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain NTF2 PF02136.20 GAM25394.1 - 2.2e-15 57.3 3.1 6.9e-15 55.7 0.2 2.5 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 GAM25394.1 - 0.0026 17.5 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UFC1 PF08694.11 GAM25395.1 - 3.6e-85 283.3 0.7 4e-85 283.1 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 GAM25395.1 - 0.0029 17.9 0.0 0.0033 17.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.26 GAM25395.1 - 0.013 15.2 0.4 0.029 14.0 0.4 1.8 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Ras PF00071.22 GAM25396.1 - 5.9e-55 185.3 0.0 6.8e-55 185.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM25396.1 - 5.1e-22 78.3 0.0 7.7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM25396.1 - 1.2e-09 37.9 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM25396.1 - 0.00011 21.8 0.0 0.00042 19.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DNA_pol_A PF00476.20 GAM25397.1 - 4.9e-92 308.9 0.1 8.5e-92 308.1 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family A Symplekin_C PF12295.8 GAM25398.1 - 1.7e-46 158.6 5.5 3.8e-46 157.5 5.5 1.6 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 GAM25399.1 - 1.6e-27 96.6 0.5 1.6e-27 96.6 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) DUF4470 PF14737.6 GAM25399.1 - 0.026 14.7 1.1 7.5 6.8 0.0 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4470) SapB_1 PF05184.15 GAM25399.1 - 0.072 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 1 PP2C PF00481.21 GAM25400.1 - 8.5e-66 222.2 0.2 1.2e-65 221.8 0.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 GAM25400.1 - 9e-05 22.2 0.1 0.00024 20.8 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PCI PF01399.27 GAM25401.1 - 9.5e-18 64.6 0.0 2.8e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 PCI domain FliD_C PF07195.12 GAM25401.1 - 0.073 12.5 0.6 0.12 11.8 0.6 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus LRR_8 PF13855.6 GAM25402.1 - 3.9e-30 103.4 24.2 7.4e-11 41.7 0.5 4.7 3 1 1 4 4 4 4 Leucine rich repeat DSPc PF00782.20 GAM25402.1 - 6.2e-29 100.5 1.0 8.2e-29 100.1 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.7 GAM25402.1 - 3.4e-18 65.5 34.7 2.8e-05 24.4 3.7 6.3 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAM25402.1 - 1.7e-08 34.2 11.6 3.1e-05 23.5 1.6 3.3 2 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 GAM25402.1 - 3.1e-05 23.9 22.8 15 6.6 0.3 9.5 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_2 PF07723.13 GAM25402.1 - 0.0025 18.4 0.1 6.6 7.6 0.0 3.7 2 0 0 2 2 2 2 Leucine Rich Repeat Y_phosphatase PF00102.27 GAM25402.1 - 0.018 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF2015 PF09435.10 GAM25402.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) DUF4050 PF13259.6 GAM25402.1 - 4.4 7.6 6.2 2.2 8.6 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) LRR_6 PF13516.6 GAM25402.1 - 7.4 6.9 33.2 6.1 7.2 0.0 8.2 10 0 0 10 10 10 0 Leucine Rich repeat RRM_5 PF13893.6 GAM25404.1 - 1.9e-35 121.2 1.4 4.8e-21 74.7 0.0 4.1 2 2 2 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GAM25404.1 - 5e-35 119.1 0.0 4.6e-08 32.8 0.0 5.0 4 1 1 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 GAM25404.1 - 3.2e-12 46.5 0.0 1.2e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 GAM25404.1 - 3.7e-07 29.9 0.4 0.55 10.1 0.0 4.4 4 0 0 4 4 4 4 Occluded RNA-recognition motif RL PF17797.1 GAM25404.1 - 0.00017 21.5 0.6 0.32 11.0 0.0 4.0 4 1 0 4 4 4 1 RL domain Ank_2 PF12796.7 GAM25405.1 - 7.2e-26 90.6 10.3 3.6e-06 27.5 0.7 5.7 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM25405.1 - 8.6e-23 80.4 10.0 8.8e-06 26.2 0.2 7.1 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM25405.1 - 6.1e-21 74.2 9.5 0.024 15.0 0.1 8.2 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM25405.1 - 1.1e-15 56.1 1.1 1.2 10.0 0.0 9.8 8 2 2 10 10 10 3 Ankyrin repeat Ank PF00023.30 GAM25405.1 - 1.4e-05 25.3 1.5 6.7 7.3 0.1 5.7 3 2 0 3 3 3 2 Ankyrin repeat DUF5049 PF16468.5 GAM25405.1 - 0.0017 18.2 1.0 50 3.9 0.0 5.6 5 1 1 6 6 6 0 Domain of unknown function (DUF5049) TRI5 PF06330.11 GAM25405.1 - 0.036 12.9 0.4 5.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Trichodiene synthase (TRI5) DNTTIP1_dimer PF18192.1 GAM25405.1 - 2.1 8.8 4.4 26 5.3 0.2 3.5 3 1 1 4 4 4 0 DNTTIP1 dimerisation domain vATP-synt_E PF01991.18 GAM25409.1 - 0.25 10.7 4.9 0.34 10.3 4.9 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Med9 PF07544.13 GAM25409.1 - 0.35 11.0 7.3 0.55 10.4 7.3 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Peptidase_C48 PF02902.19 GAM25410.1 - 2.1e-08 34.3 0.2 5e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.18 GAM25410.1 - 0.03 14.0 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 Adenovirus endoprotease DEAD PF00270.29 GAM25412.1 - 1.2e-47 162.0 0.0 2.1e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM25412.1 - 1.2e-30 106.0 0.0 4.4e-30 104.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAM25412.1 - 8.8e-06 25.1 0.1 1.5e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAM25412.1 - 0.00012 22.2 0.0 0.00031 20.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM25413.1 - 3.2e-44 150.8 0.0 9.4e-44 149.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM25413.1 - 4e-24 85.1 0.5 2.9e-23 82.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAM25413.1 - 2.3e-18 66.1 0.1 6.6e-18 64.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ELMO_CED12 PF04727.13 GAM25414.1 - 4.7e-41 140.8 0.1 6.1e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family Kelch_6 PF13964.6 GAM25415.1 - 1.5e-06 28.2 7.2 0.0025 18.0 0.0 5.0 4 1 1 5 5 5 1 Kelch motif Kelch_4 PF13418.6 GAM25415.1 - 3.3e-06 27.0 5.5 0.0039 17.2 0.1 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM25415.1 - 0.0026 17.6 3.2 0.057 13.4 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 GAM25415.1 - 0.028 14.7 0.1 17 5.8 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM25415.1 - 0.4 10.3 0.0 0.4 10.3 0.0 3.9 5 0 0 5 5 5 0 Kelch motif Kelch_6 PF13964.6 GAM25416.1 - 6.4e-11 42.1 4.5 0.00059 20.0 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM25416.1 - 8.5e-07 28.9 6.9 0.018 15.0 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM25416.1 - 4.3e-05 23.0 1.1 0.37 10.4 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 GAM25416.1 - 0.00028 21.1 2.0 1.6 9.1 0.0 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM25416.1 - 0.00041 20.2 9.7 4 7.6 0.1 5.3 6 0 0 6 6 6 3 Kelch motif DUF4368 PF14287.6 GAM25416.1 - 0.028 14.7 0.0 0.086 13.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) Kelch_5 PF13854.6 GAM25416.1 - 6.7 6.8 9.5 2.5 8.2 0.2 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 GAM25417.1 - 0.00094 19.4 0.8 0.13 12.6 0.0 3.6 3 1 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAM25417.1 - 0.0024 17.8 0.1 4.9 7.3 0.0 3.3 2 1 1 3 3 3 2 Kelch motif Peptidase_S39 PF02122.15 GAM25417.1 - 0.072 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase S39 Kelch_4 PF13418.6 GAM25417.1 - 0.53 10.3 4.9 6.9 6.8 0.1 3.5 4 1 0 4 4 4 0 Galactose oxidase, central domain T3SSipB PF16535.5 GAM25418.1 - 0.015 15.7 0.2 0.021 15.3 0.2 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB GCIP PF13324.6 GAM25418.1 - 0.02 14.5 1.1 0.03 13.9 1.1 1.5 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting Baculo_PEP_C PF04513.12 GAM25418.1 - 0.026 14.5 11.3 0.04 13.9 11.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glu-tRNAGln PF02686.15 GAM25418.1 - 0.033 14.5 1.3 0.17 12.2 0.2 2.2 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Filo_VP35 PF02097.15 GAM25418.1 - 0.038 13.1 2.0 0.044 12.9 2.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 ApbA_C PF08546.11 GAM25418.1 - 0.039 14.2 0.2 0.11 12.7 0.1 1.8 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DUF3461 PF11944.8 GAM25418.1 - 0.047 13.8 3.4 0.1 12.8 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) YkyA PF10368.9 GAM25418.1 - 0.049 13.3 4.8 0.07 12.8 4.8 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF4062 PF13271.6 GAM25418.1 - 0.097 13.1 0.9 0.18 12.2 0.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4062) RPW8 PF05659.11 GAM25418.1 - 0.11 12.2 2.3 0.37 10.5 1.7 2.2 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SopA PF13981.6 GAM25418.1 - 0.13 12.7 3.9 0.2 12.1 3.9 1.3 1 0 0 1 1 1 0 SopA-like central domain DUF3450 PF11932.8 GAM25418.1 - 0.13 11.5 2.6 0.15 11.3 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) FliT PF05400.13 GAM25418.1 - 0.14 13.0 0.1 0.47 11.3 0.1 1.8 1 1 1 2 2 2 0 Flagellar protein FliT DUF1664 PF07889.12 GAM25418.1 - 0.15 12.1 5.5 0.26 11.3 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Ssu72 PF04722.13 GAM25418.1 - 0.37 10.3 5.7 0.59 9.7 5.7 1.5 1 1 0 1 1 1 0 Ssu72-like protein DUF848 PF05852.11 GAM25418.1 - 0.38 10.8 5.1 0.072 13.2 1.2 1.8 2 1 0 2 2 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF948 PF06103.11 GAM25418.1 - 2 8.7 5.5 11 6.4 5.5 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 GAM25418.1 - 3.4 8.1 7.8 5 7.6 0.5 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SBDS_C PF09377.10 GAM25418.1 - 3.5 7.7 7.0 7.8 6.5 7.1 1.4 1 1 0 1 1 1 0 SBDS protein C-terminal domain DASH_Duo1 PF08651.10 GAM25418.1 - 5.7 6.8 13.6 1.1 9.0 0.9 3.1 1 1 0 2 2 2 0 DASH complex subunit Duo1 Kelch_6 PF13964.6 GAM25419.1 - 8.6e-05 22.7 1.8 0.027 14.7 0.0 4.4 3 2 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 GAM25419.1 - 0.0071 16.3 3.2 0.28 11.2 0.1 3.1 2 1 0 2 2 2 1 Galactose oxidase, central domain PhnA PF03831.14 GAM25419.1 - 0.024 14.5 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 PhnA domain Kelch_3 PF13415.6 GAM25419.1 - 0.41 11.0 2.0 2.8 8.3 0.0 3.1 4 0 0 4 4 4 0 Galactose oxidase, central domain UPF0370 PF13980.6 GAM25420.1 - 2.2 8.4 9.8 0.16 12.0 3.2 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) Kelch_6 PF13964.6 GAM25421.1 - 4.2e-10 39.5 5.1 0.01 16.1 0.0 4.9 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM25421.1 - 0.015 15.3 13.8 3.3 7.8 0.0 4.9 4 1 0 4 4 4 0 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM25421.1 - 0.035 13.7 2.9 1.6 8.4 0.0 3.8 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.6 GAM25421.1 - 0.14 12.2 6.2 3.8 7.6 0.2 3.3 3 0 0 3 3 3 0 Kelch motif Formyl_trans_N PF00551.19 GAM25422.1 - 7e-47 159.5 0.1 8.1e-47 159.3 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase MMR_HSR1_Xtn PF16897.5 GAM25422.1 - 0.069 13.2 0.3 2.7 8.1 0.2 2.4 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain THDPS_N_2 PF14805.6 GAM25422.1 - 0.15 12.3 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Cpn60_TCP1 PF00118.24 GAM25423.1 - 2.7e-166 554.0 0.4 3e-166 553.9 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DnaJ PF00226.31 GAM25424.1 - 8.7e-23 80.2 2.9 8.7e-23 80.2 2.9 2.1 2 0 0 2 2 2 1 DnaJ domain Pox_P35 PF03213.14 GAM25424.1 - 0.02 14.1 0.2 0.034 13.4 0.2 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein Imm6 PF14434.6 GAM25424.1 - 0.1 12.5 1.2 2.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Immunity protein Imm6 Erf4 PF10256.9 GAM25425.1 - 4.1e-07 30.1 0.1 5.2e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF2207 PF09972.9 GAM25425.1 - 0.008 15.0 0.7 0.0084 14.9 0.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) MgtE PF01769.16 GAM25425.1 - 0.045 14.1 3.1 0.055 13.9 3.1 1.1 1 0 0 1 1 1 0 Divalent cation transporter Tenui_PVC2 PF06656.11 GAM25425.1 - 0.059 11.3 5.1 0.068 11.1 5.1 1.0 1 0 0 1 1 1 0 Tenuivirus PVC2 protein BPD_transp_1 PF00528.22 GAM25425.1 - 0.11 12.3 5.8 0.13 11.9 5.8 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component FUSC PF04632.12 GAM25425.1 - 0.41 9.1 1.9 0.48 8.9 1.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ac81 PF05820.11 GAM25425.1 - 0.45 10.0 5.2 0.6 9.6 5.2 1.1 1 0 0 1 1 1 0 Baculoviridae AC81 DUF805 PF05656.14 GAM25425.1 - 0.64 10.4 4.4 0.96 9.9 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Pex24p PF06398.11 GAM25425.1 - 1.7 7.5 4.3 2 7.3 4.3 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin tRNA_bind PF01588.20 GAM25426.1 - 4.7e-28 97.1 0.2 1e-27 96.1 0.2 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 GAM25426.1 - 0.038 14.0 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Utp12 PF04003.12 GAM25427.1 - 3e-05 24.3 1.9 0.0005 20.3 0.2 2.5 1 1 1 2 2 2 1 Dip2/Utp12 Family Glyco_hydro_26 PF02156.15 GAM25427.1 - 0.036 13.5 0.5 3.6 6.9 0.1 2.3 1 1 1 2 2 2 0 Glycosyl hydrolase family 26 Peptidase_C28 PF05408.11 GAM25427.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase DUF4255 PF14065.6 GAM25427.1 - 0.076 12.7 0.1 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4255) Ribosomal_L3 PF00297.22 GAM25428.1 - 3.9e-178 592.1 7.1 4.5e-178 591.9 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 E3_UFM1_ligase PF09743.9 GAM25428.1 - 0.00064 19.4 0.4 0.00093 18.9 0.4 1.2 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 GST_C_3 PF14497.6 GAM25429.1 - 1.5e-22 79.7 0.2 2.6e-22 78.8 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM25429.1 - 4.8e-08 33.2 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM25429.1 - 1.4e-07 31.7 0.0 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM25429.1 - 0.00011 22.2 0.0 0.00047 20.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM25429.1 - 0.00014 22.1 0.0 0.0003 21.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 GAM25429.1 - 0.0019 18.9 0.0 0.0038 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GAM25429.1 - 0.0047 16.7 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF3173 PF11372.8 GAM25429.1 - 0.15 11.9 0.0 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) GST_N_2 PF13409.6 GAM25429.1 - 0.16 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ArfGap PF01412.18 GAM25430.1 - 2.6e-29 101.6 0.1 2.6e-29 101.6 0.1 2.8 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf Abhydrolase_1 PF00561.20 GAM25430.1 - 2.7 7.6 9.9 24 4.4 9.5 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_L30 PF00327.20 GAM25431.1 - 3.4e-19 68.5 0.9 7.4e-19 67.4 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 GAM25431.1 - 1.1e-09 38.3 12.4 2.5e-09 37.3 12.4 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Sod_Cu PF00080.20 GAM25432.1 - 3.8e-48 163.3 1.5 5.7e-48 162.7 1.5 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF2615 PF11027.8 GAM25432.1 - 0.064 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF4969 PF16339.5 GAM25432.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) Spo7 PF03907.13 GAM25432.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Spo7-like protein SARAF PF06682.12 GAM25432.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TPR_1 PF00515.28 GAM25433.1 - 2.6e-33 112.5 27.7 3.8e-09 36.0 0.4 8.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAM25433.1 - 1.1e-32 109.4 18.8 2.7e-06 27.1 0.1 8.2 9 0 0 9 9 8 5 Tetratricopeptide repeat DnaJ PF00226.31 GAM25433.1 - 1.9e-25 88.7 1.9 5.4e-25 87.3 1.9 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 GAM25433.1 - 6.6e-21 74.6 16.3 7.4e-05 23.2 0.2 7.2 5 1 2 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.6 GAM25433.1 - 1.8e-20 71.3 16.0 0.00018 21.5 0.1 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM25433.1 - 7.9e-19 67.1 17.9 2.1e-05 24.1 0.3 7.7 5 2 3 8 8 8 4 TPR repeat TPR_16 PF13432.6 GAM25433.1 - 8.1e-14 52.0 3.0 9.4e-05 23.0 0.0 5.7 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM25433.1 - 4.5e-12 45.5 16.7 9.7e-06 25.6 0.0 8.4 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM25433.1 - 8e-12 45.3 14.1 0.0088 16.3 0.4 5.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM25433.1 - 2.4e-11 43.5 1.4 0.46 11.4 0.1 6.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM25433.1 - 1.1e-09 37.6 6.0 0.021 14.9 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAM25433.1 - 1.7e-06 27.5 10.0 0.005 16.1 6.8 3.8 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM25433.1 - 3.6e-06 27.0 0.8 0.0038 17.3 0.1 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM25433.1 - 2.1e-05 24.6 19.3 0.092 13.0 1.0 5.3 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 GAM25433.1 - 0.0026 17.8 7.5 7.4 6.7 0.2 5.9 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 GAM25433.1 - 0.0041 17.6 3.4 0.13 12.7 0.7 4.1 3 2 0 3 3 3 1 Bacterial transcriptional activator domain TPR_MalT PF17874.1 GAM25433.1 - 0.016 14.6 5.8 0.022 14.2 0.4 3.0 2 1 1 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 GAM25433.1 - 0.059 13.3 8.7 3.5 7.6 0.1 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.18 GAM25433.1 - 0.085 12.9 19.7 0.098 12.7 0.6 6.1 5 2 2 7 7 7 0 MIT (microtubule interacting and transport) domain Terminase_3C PF17288.2 GAM25433.1 - 0.089 13.2 4.7 0.21 12.0 1.0 2.8 2 1 0 2 2 2 0 Terminase RNAseH like domain TPR_6 PF13174.6 GAM25433.1 - 0.11 13.2 20.9 0.62 10.8 0.1 7.2 8 2 1 9 9 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAM25433.1 - 0.35 10.3 15.3 0.8 9.2 0.2 5.6 7 0 0 7 7 7 0 SHNi-TPR TOM20_plant PF06552.12 GAM25433.1 - 0.49 10.1 10.0 1 9.1 1.3 4.0 2 1 2 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 Rapsyn_N PF10579.9 GAM25433.1 - 0.92 9.7 3.6 53 4.0 0.0 4.1 5 0 0 5 5 3 0 Rapsyn N-terminal myristoylation and linker region Sel1 PF08238.12 GAM25433.1 - 1.4 9.7 6.1 2.6 8.9 0.1 4.1 4 0 0 4 4 3 0 Sel1 repeat Cnd3 PF12719.7 GAM25434.1 - 2.4e-16 59.8 2.6 1e-15 57.7 1.6 2.5 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 GAM25434.1 - 1.8e-06 27.7 2.3 11 6.6 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 GAM25434.1 - 9.2e-06 25.8 8.4 0.0017 18.4 0.6 5.0 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM25434.1 - 2.7e-05 24.5 0.0 0.0045 17.3 0.0 3.5 2 2 2 4 4 4 1 HEAT repeats CRF1 PF10380.9 GAM25434.1 - 0.35 11.2 4.3 0.61 10.4 3.1 2.1 1 1 1 2 2 2 0 Transcription factor CRF1 Phage_int_SAM_5 PF13102.6 GAM25434.1 - 1.3 9.4 8.7 48 4.4 0.0 4.1 4 0 0 4 4 4 0 Phage integrase SAM-like domain Spt5_N PF11942.8 GAM25434.1 - 5 8.2 13.9 15 6.7 1.3 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FNIP PF05725.12 GAM25435.1 - 1.7e-88 290.6 40.6 1.1e-12 47.9 1.5 12.4 8 2 5 13 13 13 12 FNIP Repeat DUF4746 PF15928.5 GAM25436.1 - 0.00091 18.7 6.9 0.0016 17.9 6.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) Na_trans_assoc PF06512.13 GAM25436.1 - 0.0022 18.3 1.9 0.0031 17.8 1.9 1.3 1 0 0 1 1 1 1 Sodium ion transport-associated RNA_pol_3_Rpc31 PF11705.8 GAM25436.1 - 0.0054 17.0 7.8 0.0054 17.0 7.8 1.5 2 0 0 2 2 1 1 DNA-directed RNA polymerase III subunit Rpc31 Presenilin PF01080.17 GAM25436.1 - 0.0075 15.1 1.1 0.0096 14.7 1.1 1.1 1 0 0 1 1 1 1 Presenilin Tim54 PF11711.8 GAM25436.1 - 0.015 14.1 1.4 0.025 13.4 1.4 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 2OG-FeII_Oxy_3 PF13640.6 GAM25436.1 - 0.032 15.1 0.0 0.083 13.8 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Sec62 PF03839.16 GAM25436.1 - 0.065 12.7 4.0 0.11 12.0 4.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DNA_pol_phi PF04931.13 GAM25436.1 - 0.069 11.3 5.4 0.097 10.8 5.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 GAM25436.1 - 0.091 13.2 9.5 0.24 11.8 9.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Imm5 PF14423.6 GAM25436.1 - 0.1 12.8 0.7 0.18 12.0 0.7 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 NOA36 PF06524.12 GAM25436.1 - 0.1 11.9 6.0 0.18 11.1 6.0 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 GAM25436.1 - 0.17 11.6 10.8 0.28 10.9 10.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF-3c_N PF05470.12 GAM25436.1 - 0.17 10.2 4.7 0.23 9.7 4.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FAM176 PF14851.6 GAM25436.1 - 0.56 9.9 4.5 1.3 8.7 3.5 2.1 2 0 0 2 2 2 0 FAM176 family PIEZO PF15917.5 GAM25436.1 - 3.6 7.0 5.2 6.4 6.2 5.2 1.3 1 0 0 1 1 1 0 Piezo TIG PF01833.24 GAM25437.1 - 9.6e-29 99.3 65.5 1.8e-08 34.3 8.1 8.3 8 1 1 9 9 9 5 IPT/TIG domain EGF_2 PF07974.13 GAM25437.1 - 0.056 13.8 11.3 0.1 13.0 11.3 1.4 1 0 0 1 1 1 0 EGF-like domain T4BSS_DotH_IcmK PF12293.8 GAM25437.1 - 0.29 10.4 5.6 2.5 7.3 0.0 3.2 1 1 2 3 3 3 0 Putative outer membrane core complex of type IVb secretion F5_F8_type_C PF00754.25 GAM25438.1 - 9.1e-21 74.3 0.3 1.5e-20 73.6 0.3 1.3 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.10 GAM25438.1 - 2e-17 63.1 0.6 6.3e-17 61.5 0.6 1.8 1 0 0 1 1 1 1 H-type lectin domain Choline_transpo PF04515.12 GAM25439.1 - 9.9e-79 264.9 34.8 9.9e-79 264.9 34.8 2.4 2 1 0 2 2 2 1 Plasma-membrane choline transporter VirB3 PF05101.13 GAM25439.1 - 0.14 12.4 0.0 0.14 12.4 0.0 5.5 6 3 0 6 6 6 0 Type IV secretory pathway, VirB3-like protein DUF2371 PF10177.9 GAM25439.1 - 8.9 6.5 9.1 1 9.6 0.6 3.3 3 1 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) Sec1 PF00995.23 GAM25440.1 - 3.9e-114 383.0 9.5 4.5e-114 382.8 9.5 1.0 1 0 0 1 1 1 1 Sec1 family Syja_N PF02383.18 GAM25441.1 - 7.2e-81 272.0 0.5 9.1e-81 271.6 0.5 1.1 1 0 0 1 1 1 1 SacI homology domain eRF1_2 PF03464.15 GAM25442.1 - 1.3e-42 145.3 0.0 2.3e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAM25442.1 - 2.7e-35 121.3 0.4 8.8e-35 119.6 0.1 2.0 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 GAM25442.1 - 4.7e-16 59.0 0.0 7.6e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 GAM25442.1 - 5.4e-09 36.4 0.0 1.5e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 GAM25442.1 - 1.7e-08 34.9 0.0 2.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor AA_permease_2 PF13520.6 GAM25443.1 - 1.6e-53 182.1 52.1 1.6e-53 182.1 52.1 1.6 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 GAM25443.1 - 2e-42 145.4 41.3 2e-42 145.4 41.3 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 GAM25443.1 - 4.4e-18 65.1 1.7 4.4e-18 65.1 1.7 4.0 5 0 0 5 5 5 1 C-terminus of AA_permease Spore_permease PF03845.13 GAM25443.1 - 2.1e-06 26.8 22.3 2.1e-06 26.8 22.3 3.3 3 1 0 3 3 3 1 Spore germination protein FixQ PF05545.11 GAM25443.1 - 5.3 7.1 11.6 3.4 7.7 0.7 3.8 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ SET PF00856.28 GAM25444.1 - 7e-08 33.0 0.0 7.3e-07 29.7 0.0 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 GAM25444.1 - 1.5e-05 25.0 3.4 1.5e-05 25.0 3.4 2.4 2 0 0 2 2 2 1 MYND finger Metallothio_Pro PF02069.16 GAM25444.1 - 4.1 7.7 11.8 0.32 11.3 2.9 2.6 2 0 0 2 2 2 0 Prokaryotic metallothionein FNIP PF05725.12 GAM25445.1 - 5.6e-14 52.0 15.4 6.1e-08 32.7 0.5 6.5 6 1 1 7 7 7 2 FNIP Repeat MutS_V PF00488.21 GAM25446.1 - 2e-73 246.5 0.0 3.7e-73 245.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAM25446.1 - 8.8e-30 104.4 0.3 8.8e-30 104.4 0.3 2.3 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 GAM25446.1 - 2e-28 98.9 0.5 6.2e-28 97.3 0.3 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 GAM25446.1 - 7.7e-14 52.1 0.1 4e-13 49.8 0.1 2.3 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 GAM25446.1 - 6.9e-07 29.5 2.4 2e-06 28.1 2.4 1.8 1 0 0 1 1 1 1 MutS family domain IV MatE PF01554.18 GAM25447.1 - 1.7e-05 24.5 16.7 0.019 14.6 7.3 3.7 2 2 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAM25447.1 - 0.00027 21.0 5.0 0.00027 21.0 5.0 3.3 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain FtsH_ext PF06480.15 GAM25447.1 - 0.084 13.2 0.3 0.084 13.2 0.3 2.5 2 1 0 2 2 2 0 FtsH Extracellular DNA_pol_A_exo1 PF01612.20 GAM25448.1 - 6.6e-17 61.8 0.0 1.6e-16 60.5 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Mucin PF01456.17 GAM25448.1 - 0.0041 17.1 2.6 0.0088 16.0 2.6 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein COX14 PF14880.6 GAM25448.1 - 0.016 15.0 0.1 0.05 13.4 0.1 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DUF5130 PF17174.4 GAM25448.1 - 0.052 13.8 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) Hydin_ADK PF17213.3 GAM25448.1 - 0.21 11.8 2.6 2 8.7 0.0 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF846 PF05832.12 GAM25449.1 - 1.6e-49 167.5 14.8 2e-49 167.2 14.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) VIT1 PF01988.19 GAM25449.1 - 1.2 9.0 6.0 5.8 6.7 0.1 2.1 2 0 0 2 2 2 0 VIT family Phage_holin_3_6 PF07332.11 GAM25449.1 - 4.3 7.4 10.1 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DSPc PF00782.20 GAM25450.1 - 2.3e-07 30.7 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM25450.1 - 6.7e-07 29.1 0.0 8.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 GAM25450.1 - 3.2e-05 23.6 0.0 4.8e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 GAM25450.1 - 0.00022 21.4 0.0 0.00029 21.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Ala_racemase_N PF01168.20 GAM25452.1 - 2.2e-21 76.5 0.0 2.5e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Herpes_U5 PF05999.11 GAM25452.1 - 0.15 10.8 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family PH PF00169.29 GAM25453.1 - 1.2e-31 109.3 2.9 4.7e-12 46.3 0.3 3.8 3 1 0 3 3 3 3 PH domain PH_11 PF15413.6 GAM25453.1 - 1.2e-08 35.3 5.0 0.2 12.1 0.0 4.8 3 2 0 3 3 3 3 Pleckstrin homology domain PH_9 PF15410.6 GAM25453.1 - 0.0081 16.5 0.3 0.13 12.7 0.3 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain GSHPx PF00255.19 GAM25454.1 - 0.0045 16.5 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.19 GAM25455.1 - 8.2e-17 60.7 0.2 1.1e-16 60.4 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase IFT81_CH PF18383.1 GAM25455.1 - 0.061 13.6 0.0 0.095 13.0 0.0 1.2 1 0 0 1 1 1 0 Intraflagellar transport 81 calponin homology domain HMG_box PF00505.19 GAM25456.1 - 2e-08 34.5 0.1 3.5e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAM25456.1 - 0.00015 22.3 0.2 0.00023 21.7 0.2 1.3 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 GAM25456.1 - 0.02 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain Cut8 PF08559.10 GAM25457.1 - 6e-28 98.1 39.0 3.9e-25 88.9 39.0 2.8 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein FAM222A PF15258.6 GAM25457.1 - 0.02 14.0 38.8 0.031 13.4 38.8 1.4 1 0 0 1 1 1 0 Protein family of FAM222A DUF812 PF05667.11 GAM25457.1 - 0.12 11.2 30.8 0.37 9.6 15.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Otopetrin PF03189.13 GAM25457.1 - 1.8 7.3 10.8 2.6 6.7 10.8 1.4 1 0 0 1 1 1 0 Otopetrin DUF4746 PF15928.5 GAM25457.1 - 7.2 5.9 15.6 0.39 10.1 10.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) ACOX PF01756.19 GAM25458.1 - 5.5e-18 65.1 0.0 8.6e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 GAM25458.1 - 3.7e-13 49.5 0.0 6.8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 GAM25458.1 - 1.1e-06 29.3 0.0 2.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 GAM25458.1 - 0.00016 21.9 0.0 0.00048 20.4 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAM25458.1 - 0.034 14.8 0.0 0.083 13.6 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Frizzled PF01534.17 GAM25459.1 - 0.00034 19.7 2.3 0.00063 18.9 1.3 1.9 1 1 1 2 2 2 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 GAM25459.1 - 0.00041 19.7 2.9 0.00064 19.1 2.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 GAM25459.1 - 0.021 14.9 0.1 0.054 13.6 0.1 1.8 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term MitMem_reg PF13012.6 GAM25460.1 - 2.6e-30 105.1 0.1 4.7e-30 104.3 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAM25460.1 - 4.8e-22 78.2 0.0 1e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DNA_topoisoIV PF00521.20 GAM25461.1 - 6e-115 384.5 0.8 9.6e-115 383.9 0.8 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 GAM25461.1 - 2.4e-41 141.0 3.6 2.4e-41 141.0 3.6 2.8 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 GAM25461.1 - 8.3e-23 80.7 0.8 1.9e-22 79.6 0.8 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 GAM25461.1 - 3.5e-11 43.6 0.1 9.4e-11 42.2 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GAM25461.1 - 1.1e-07 32.0 0.0 5.8e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Toprim domain gp45-slide_C PF09116.10 GAM25461.1 - 0.045 13.8 0.2 0.15 12.2 0.2 1.9 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal Nucleoporin_FG PF13634.6 GAM25461.1 - 0.12 13.2 2.7 0.51 11.2 2.7 2.1 1 0 0 1 1 1 0 Nucleoporin FG repeat region PHD PF00628.29 GAM25462.1 - 2.6e-09 36.8 7.8 2.6e-09 36.8 7.8 1.8 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 GAM25462.1 - 0.086 13.1 1.4 0.22 11.8 1.4 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain ADK_lid PF05191.14 GAM25462.1 - 8.4 6.5 7.3 0.58 10.2 1.7 2.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid Coiled PF05710.12 GAM25464.1 - 0.13 13.1 13.6 0.18 12.6 13.6 1.3 1 1 0 1 1 1 0 Coiled coil Secretin_N_2 PF07655.13 GAM25464.1 - 0.35 11.4 6.4 0.41 11.2 6.2 1.4 1 1 0 1 1 1 0 Secretin N-terminal domain RNA_pol_L_2 PF13656.6 GAM25465.1 - 9.9e-27 92.5 0.2 1.3e-26 92.1 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 GAM25465.1 - 6.5e-05 22.3 0.0 9.2e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Nuf2 PF03800.14 GAM25466.1 - 0.002 18.3 0.2 0.003 17.7 0.2 1.4 1 0 0 1 1 1 1 Nuf2 family FNIP PF05725.12 GAM25467.1 - 6.3e-46 154.3 21.5 1.1e-12 47.9 0.3 8.6 7 1 2 9 9 9 8 FNIP Repeat Lipoxygenase PF00305.19 GAM25469.1 - 4.2e-52 177.5 0.2 5.7e-52 177.1 0.2 1.0 1 0 0 1 1 1 1 Lipoxygenase HATPase_c PF02518.26 GAM25470.1 - 6.1e-27 94.3 0.0 1.4e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM25470.1 - 1.3e-19 70.5 0.1 5e-19 68.5 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAM25470.1 - 3.9e-11 42.8 0.4 1.2e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 GAM25470.1 - 4.9e-08 32.8 0.0 2e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 GAM25470.1 - 6.4e-08 32.8 0.0 1.5e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 GAM25470.1 - 1.6e-07 31.3 0.7 8e-07 29.0 0.0 2.6 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 GAM25470.1 - 0.0001 22.5 0.0 0.00056 20.1 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 GAM25470.1 - 0.055 13.8 0.0 0.18 12.1 0.0 2.0 1 0 0 1 1 1 0 PAS fold Androgen_recep PF02166.16 GAM25470.1 - 4 6.2 8.0 6.3 5.5 8.0 1.2 1 0 0 1 1 1 0 Androgen receptor Methyltransf_2 PF00891.18 GAM25471.1 - 1.4e-40 138.9 0.0 1.7e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 GAM25471.1 - 2.9e-09 36.8 0.1 8.9e-08 32.0 0.0 3.1 3 1 1 4 4 4 1 Dimerisation domain HTH_IclR PF09339.10 GAM25471.1 - 0.0028 17.4 0.0 0.066 13.0 0.0 2.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_28 PF13518.6 GAM25471.1 - 0.0065 16.6 0.0 0.069 13.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 GAM25471.1 - 0.019 14.8 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain TrmB PF01978.19 GAM25471.1 - 0.037 13.9 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_47 PF16221.5 GAM25471.1 - 0.13 11.8 0.0 1.6 8.3 0.0 2.5 2 1 0 2 2 2 0 winged helix-turn-helix HTH_24 PF13412.6 GAM25471.1 - 0.16 11.5 0.0 7.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Pkinase PF00069.25 GAM25472.1 - 4.6e-53 180.3 0.2 1.3e-52 178.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25472.1 - 6e-28 97.8 0.0 1.3e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.12 GAM25472.1 - 6.9e-06 26.0 1.1 2.6e-05 24.2 0.1 2.4 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 FTA2 PF13095.6 GAM25472.1 - 0.00021 21.0 3.5 1.5 8.4 0.1 4.0 3 1 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAM25472.1 - 0.00084 18.7 0.2 0.0021 17.4 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM25472.1 - 0.0048 16.5 0.5 0.014 15.0 0.5 1.8 1 0 0 1 1 1 1 RIO1 family Mad3_BUB1_I_2 PF17014.5 GAM25472.1 - 0.013 15.6 0.2 0.035 14.2 0.2 1.7 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein APH PF01636.23 GAM25472.1 - 0.018 15.0 0.1 0.018 15.0 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family FNIP PF05725.12 GAM25473.1 - 2.5e-44 149.2 12.7 6e-14 51.9 0.2 7.3 7 1 0 7 7 7 5 FNIP Repeat Kelch_6 PF13964.6 GAM25474.1 - 1.7e-40 136.0 10.7 1.2e-09 38.1 0.1 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 GAM25474.1 - 3.7e-38 128.9 15.2 1.4e-10 40.6 0.1 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_4 PF13418.6 GAM25474.1 - 2e-31 107.7 20.6 3e-07 30.3 0.2 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM25474.1 - 7.3e-29 98.6 12.4 1e-08 34.8 0.2 7.5 6 1 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 GAM25474.1 - 2.3e-25 88.1 11.8 0.00043 20.2 0.0 7.0 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 GAM25474.1 - 2.7e-22 78.5 13.7 1.2e-09 38.2 0.0 7.9 7 0 0 7 7 7 3 Galactose oxidase, central domain F-box-like PF12937.7 GAM25474.1 - 1.3e-05 25.0 0.1 4.5e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAM25474.1 - 0.024 14.5 0.4 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 F-box domain CH PF00307.31 GAM25475.1 - 1.8e-33 115.0 0.3 8.9e-18 64.5 0.0 3.1 2 0 0 2 2 2 2 Calponin homology (CH) domain DUF1043 PF06295.12 GAM25475.1 - 0.0088 16.0 5.3 0.0088 16.0 5.3 7.7 4 2 4 8 8 8 1 Protein of unknown function (DUF1043) Peptidase_M54 PF07998.11 GAM25475.1 - 0.22 11.5 3.0 1.3 8.9 3.0 2.4 1 1 0 1 1 1 0 Peptidase family M54 AIDA PF16168.5 GAM25476.1 - 0.011 15.8 1.4 0.022 14.9 1.4 1.6 1 0 0 1 1 1 0 Adhesin of bacterial autotransporter system, probable stalk FTA2 PF13095.6 GAM25478.1 - 7.8e-05 22.4 0.0 0.11 12.1 0.0 2.6 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 GAM25478.1 - 9.2e-05 21.9 0.1 0.0003 20.3 0.1 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 GAM25478.1 - 0.0031 16.4 0.4 0.011 14.6 0.5 1.7 1 1 1 2 2 2 1 Fungal protein kinase QCR10 PF09796.9 GAM25480.1 - 0.014 15.5 0.3 0.028 14.4 0.3 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TraL PF07178.11 GAM25480.1 - 0.032 14.7 0.2 0.076 13.5 0.2 1.5 1 0 0 1 1 1 0 TraL protein Aida_C2 PF14186.6 GAM25480.1 - 0.89 9.2 2.7 6.9 6.3 0.0 2.6 3 0 0 3 3 3 0 Cytoskeletal adhesion Cnd2 PF05786.14 GAM25482.1 - 7.4e-135 451.5 23.9 1.1e-134 450.9 23.9 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 GAM25482.1 - 1.9e-06 28.1 0.4 1.9e-06 28.1 0.4 2.8 2 1 1 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal BLOC1S3 PF15753.5 GAM25483.1 - 0.02 15.0 1.1 0.02 15.0 1.1 3.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Hamartin PF04388.12 GAM25483.1 - 0.91 8.1 19.0 1.6 7.3 19.0 1.4 1 1 0 1 1 1 0 Hamartin protein PAP1 PF08601.10 GAM25483.1 - 2.1 8.0 17.8 2.6 7.7 17.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DEAD PF00270.29 GAM25484.1 - 2.5e-42 144.6 0.4 9.7e-42 142.7 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM25484.1 - 4e-25 88.3 1.2 1e-24 87.0 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 GAM25484.1 - 0.016 14.5 3.0 0.033 13.5 0.0 2.8 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit FNIP PF05725.12 GAM25485.1 - 4.3e-90 295.7 30.0 2.3e-14 53.3 0.0 11.2 6 3 4 11 11 11 11 FNIP Repeat RRM_1 PF00076.22 GAM25486.1 - 5.7e-22 77.3 0.1 1.1e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 GAM25486.1 - 8e-15 55.1 14.3 8e-15 55.1 14.3 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_7 PF16367.5 GAM25486.1 - 0.0038 17.3 0.1 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif FlbT PF07378.11 GAM25486.1 - 0.043 13.9 1.0 0.077 13.1 1.0 1.3 1 0 0 1 1 1 0 Flagellar protein FlbT YflT PF11181.8 GAM25486.1 - 0.16 12.5 0.5 0.34 11.5 0.0 1.7 2 0 0 2 2 2 0 Heat induced stress protein YflT adh_short PF00106.25 GAM25487.1 - 5.8e-25 87.9 0.0 1.3e-24 86.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAM25487.1 - 9.2e-10 38.7 0.0 1.6e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAM25487.1 - 1.1e-06 28.4 0.0 1.9e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 GAM25487.1 - 0.00039 20.7 0.0 0.0016 18.7 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Baculo_LEF-11 PF06385.12 GAM25487.1 - 0.0054 17.2 0.1 0.01 16.3 0.1 1.5 1 0 0 1 1 1 1 Baculovirus LEF-11 protein DDE_Tnp_4 PF13359.6 GAM25487.1 - 0.0084 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Semialdhyde_dh PF01118.24 GAM25487.1 - 0.1 13.0 0.0 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAM25487.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 GAM25487.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Bromodomain PF00439.25 GAM25488.1 - 3.2e-20 72.0 0.3 8.2e-20 70.7 0.3 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 GAM25488.1 - 1.8e-08 34.3 0.1 4.7e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated Metallophos PF00149.28 GAM25490.1 - 1.8e-09 38.4 1.9 1.8e-09 38.4 1.9 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SapB_2 PF03489.17 GAM25490.1 - 0.00012 22.1 0.4 0.00039 20.5 0.4 2.0 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.15 GAM25490.1 - 0.00024 21.0 2.1 0.00052 20.0 2.1 1.6 1 0 0 1 1 1 1 Saposin-like type B, region 1 CorA PF01544.18 GAM25491.1 - 9.3e-50 169.6 5.7 9.5e-33 113.8 2.4 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein MARVEL PF01284.23 GAM25491.1 - 0.071 13.1 1.5 0.13 12.3 1.5 1.4 1 0 0 1 1 1 0 Membrane-associating domain TERB2 PF15101.6 GAM25493.1 - 0.044 13.8 0.1 0.046 13.8 0.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Rap_GAP PF02145.15 GAM25494.1 - 4.9e-59 199.0 0.3 9e-59 198.1 0.0 1.6 2 0 0 2 2 2 1 Rap/ran-GAP DUF4788 PF16032.5 GAM25494.1 - 0.14 11.0 0.9 0.3 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4788) Prenyltransf PF01255.19 GAM25495.1 - 0.00057 19.5 0.1 0.00087 18.9 0.1 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase FYVE PF01363.21 GAM25496.1 - 9.6e-07 28.9 11.4 3.2e-06 27.2 11.4 1.9 1 0 0 1 1 1 1 FYVE zinc finger Lzipper-MIP1 PF14389.6 GAM25496.1 - 6.6 7.1 55.6 0.41 11.0 4.2 7.2 5 1 2 7 7 7 0 Leucine-zipper of ternary complex factor MIP1 zf-RING_UBOX PF13445.6 GAM25497.1 - 0.0001 22.2 1.6 0.0003 20.8 1.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAM25497.1 - 0.001 19.1 4.5 0.003 17.7 4.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 GAM25497.1 - 0.0022 17.9 1.6 0.0056 16.6 1.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain PKcGMP_CC PF16808.5 GAM25497.1 - 0.0025 17.6 1.3 0.0057 16.5 1.3 1.6 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Sina PF03145.16 GAM25497.1 - 0.0033 17.4 4.8 0.9 9.5 0.1 2.4 2 0 0 2 2 2 2 Seven in absentia protein family zf-C3HC4 PF00097.25 GAM25497.1 - 0.004 17.0 4.8 0.012 15.5 4.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM25497.1 - 0.0093 15.8 4.1 0.029 14.2 4.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GAM25497.1 - 0.024 14.5 1.4 0.067 13.1 1.4 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GAM25497.1 - 0.12 12.6 3.1 0.42 10.9 3.1 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain TM2 PF05154.16 GAM25498.1 - 1.7e-21 76.2 8.2 2.6e-21 75.7 8.2 1.2 1 0 0 1 1 1 1 TM2 domain ubiquitin PF00240.23 GAM25500.1 - 3e-34 116.6 0.4 3.9e-34 116.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 GAM25500.1 - 1.4e-30 104.9 12.6 2.1e-30 104.3 12.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 GAM25500.1 - 6.6e-16 57.9 0.4 8.8e-16 57.5 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAM25500.1 - 3.3e-05 24.3 0.1 0.00013 22.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 GAM25500.1 - 0.0048 17.2 0.1 0.0079 16.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAM25500.1 - 0.0094 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM25500.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 GAM25500.1 - 0.021 14.8 0.7 6.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 GAM25500.1 - 0.063 13.8 0.1 0.067 13.8 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Orn_Arg_deC_N PF02784.16 GAM25501.1 - 5.2e-40 137.4 0.0 6.6e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 GAM25501.1 - 5.6e-11 42.5 0.0 6.6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DHR-2 PF06920.13 GAM25503.1 - 1.3e-45 156.1 8.7 7.1e-45 153.6 8.7 2.0 1 1 0 1 1 1 1 Dock homology region 2 F-box-like PF12937.7 GAM25503.1 - 3.7e-09 36.3 0.2 1.1e-08 34.8 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM25503.1 - 0.00046 20.0 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUF3246 PF11596.8 GAM25504.1 - 0.00023 20.7 7.5 0.00023 20.7 7.5 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3246) RPN7 PF10602.9 GAM25504.1 - 0.0009 19.0 3.8 1.4 8.6 0.1 4.2 4 0 0 4 4 4 2 26S proteasome subunit RPN7 TPR_8 PF13181.6 GAM25504.1 - 0.045 14.0 16.1 12 6.4 1.9 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM25504.1 - 0.18 11.9 1.0 16 5.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM25504.1 - 1.3 9.3 25.9 1.4 9.3 0.0 7.5 9 1 0 9 9 9 0 Tetratricopeptide repeat AA_permease_2 PF13520.6 GAM25505.1 - 1.9e-56 191.7 36.7 1.9e-56 191.7 36.7 2.1 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 GAM25505.1 - 2.4e-39 135.3 39.9 2.4e-39 135.3 39.9 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 GAM25505.1 - 2e-22 79.0 8.9 2e-22 79.0 8.9 3.8 4 0 0 4 4 4 1 C-terminus of AA_permease Spore_permease PF03845.13 GAM25505.1 - 0.00063 18.7 14.5 0.00063 18.7 14.5 3.2 2 2 0 2 2 2 1 Spore germination protein EF-hand_7 PF13499.6 GAM25506.1 - 3.4e-17 62.7 16.3 1.5e-11 44.6 0.4 4.4 5 0 0 5 5 4 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM25506.1 - 4.7e-16 57.3 2.4 8.8e-05 22.1 0.1 4.2 4 0 0 4 4 3 3 EF-hand domain EF-hand_1 PF00036.32 GAM25506.1 - 1.5e-15 55.5 12.6 2.2e-05 23.7 0.3 4.3 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 GAM25506.1 - 1.2e-12 47.4 2.9 3e-07 30.2 0.8 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 GAM25506.1 - 2.6e-09 36.2 8.8 0.011 15.2 0.2 4.6 4 0 0 4 4 4 3 EF hand TSC22 PF01166.18 GAM25506.1 - 6.2e-06 26.4 6.7 6.6e-05 23.1 1.8 9.6 6 3 5 11 11 11 2 TSC-22/dip/bun family EF-hand_9 PF14658.6 GAM25506.1 - 0.00081 19.7 0.7 0.033 14.5 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain Spc42p PF11544.8 GAM25506.1 - 0.0073 16.3 4.7 0.0073 16.3 4.7 6.0 4 2 1 5 5 5 1 Spindle pole body component Spc42p BLOC1_2 PF10046.9 GAM25506.1 - 0.011 16.0 7.0 0.011 16.0 7.0 8.1 3 2 4 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bacillus_PapR PF05968.11 GAM25506.1 - 0.58 10.1 2.4 0.65 9.9 0.6 2.0 2 0 0 2 2 2 0 Bacillus PapR protein Spc7 PF08317.11 GAM25506.1 - 3.5 6.4 74.6 0.28 10.0 14.5 4.8 3 1 1 4 4 4 0 Spc7 kinetochore protein Innate_immun PF12782.7 GAM25506.1 - 4.7 6.6 8.0 9.4 5.6 8.0 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family ZapB PF06005.12 GAM25506.1 - 8.5 6.9 88.3 0.1 13.1 0.4 9.7 7 3 1 8 8 8 0 Cell division protein ZapB GST_N_3 PF13417.6 GAM25508.1 - 3.2e-09 37.1 0.0 4.1e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAM25508.1 - 9.7e-09 35.5 0.1 2.6e-07 30.9 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM25508.1 - 4.5e-08 33.3 0.0 8.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM25508.1 - 1.5e-06 28.3 0.2 2.3e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM25508.1 - 4.9e-06 26.7 0.1 7.8e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM25508.1 - 0.0027 17.7 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PH PF00169.29 GAM25509.1 - 7.6e-14 52.1 0.6 1.8e-13 50.9 0.6 1.7 1 0 0 1 1 1 1 PH domain PH_10 PF15411.6 GAM25509.1 - 0.013 15.7 0.5 0.032 14.5 0.5 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 GAM25509.1 - 0.043 13.6 0.3 0.086 12.6 0.3 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Coiled PF05710.12 GAM25510.1 - 0.0082 16.9 30.8 0.03 15.2 30.8 1.8 1 1 0 1 1 1 1 Coiled coil EAF PF09816.9 GAM25511.1 - 2.8e-13 50.1 1.9 3.3e-13 49.9 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor AF-4 PF05110.13 GAM25511.1 - 0.00063 18.0 31.4 0.0016 16.7 7.5 2.1 2 0 0 2 2 2 2 AF-4 proto-oncoprotein SCAPER_N PF16501.5 GAM25512.1 - 7.3e-08 32.3 0.0 2.7e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 S phase cyclin A-associated protein in the endoplasmic reticulum zf-met PF12874.7 GAM25512.1 - 0.024 15.0 0.1 0.024 15.0 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CBM32 PF18344.1 GAM25512.1 - 0.034 14.0 0.2 0.16 11.9 0.2 2.2 1 0 0 1 1 1 0 Carbohydrate binding module family 32 zf-C2H2_jaz PF12171.8 GAM25512.1 - 0.076 13.3 2.3 0.12 12.7 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Serglycin PF04360.12 GAM25512.1 - 0.082 12.8 3.7 0.24 11.3 3.7 1.8 1 0 0 1 1 1 0 Serglycin zf-C2H2_2 PF12756.7 GAM25512.1 - 0.13 12.6 0.1 0.13 12.6 0.1 2.9 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF4326 PF14216.6 GAM25513.1 - 1.3e-23 83.5 0.1 2.2e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) MtrH PF02007.18 GAM25513.1 - 0.048 12.8 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit FGGY_N PF00370.21 GAM25515.1 - 2.4e-47 161.6 0.5 5.1e-46 157.2 0.5 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAM25515.1 - 2.2e-39 135.3 1.1 6.5e-38 130.4 0.3 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hexokinase_1 PF00349.21 GAM25515.1 - 0.017 15.1 0.2 0.58 10.0 0.1 2.4 2 0 0 2 2 2 0 Hexokinase SSP160 PF06933.11 GAM25515.1 - 5.5 5.1 17.1 9.1 4.3 17.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 2-oxoacid_dh PF00198.23 GAM25516.1 - 5.4e-78 261.6 0.0 8e-78 261.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAM25516.1 - 1.2e-38 130.8 2.5 1.5e-18 66.4 0.1 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 GAM25516.1 - 1.9e-14 53.7 0.4 5.6e-14 52.2 0.4 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GAM25516.1 - 1.6e-07 31.0 0.0 0.0064 16.3 0.0 2.8 2 0 0 2 2 2 2 Biotin-lipoyl like QRPTase_N PF02749.16 GAM25516.1 - 0.011 15.8 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain E_Pc_C PF06752.12 GAM25516.1 - 0.026 14.6 0.1 0.026 14.6 0.1 3.0 2 1 1 3 3 3 0 Enhancer of Polycomb C-terminus HlyD_3 PF13437.6 GAM25516.1 - 0.036 14.8 0.0 7.6 7.3 0.0 2.6 2 0 0 2 2 2 0 HlyD family secretion protein HlyD_2 PF12700.7 GAM25516.1 - 0.041 12.6 3.2 4.4 5.9 0.0 3.2 3 0 0 3 3 3 0 HlyD family secretion protein GCV_H PF01597.19 GAM25516.1 - 0.061 13.2 0.1 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Glycine cleavage H-protein DUF3597 PF12200.8 GAM25516.1 - 3.9 8.0 17.9 5.9 7.4 3.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Sulfate_transp PF00916.20 GAM25517.1 - 1.4e-105 353.2 19.6 2e-105 352.7 19.6 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAM25517.1 - 1.3e-21 76.4 0.1 2.5e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAM25517.1 - 0.0011 19.3 3.8 0.0011 19.3 3.8 3.3 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily WD40 PF00400.32 GAM25518.1 - 4.1e-23 81.2 27.7 1.1e-05 26.0 0.8 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM25518.1 - 3.1e-06 27.4 0.1 0.88 9.9 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Tox-ART-HYD1 PF15633.6 GAM25518.1 - 0.13 12.9 1.7 0.32 11.7 1.7 1.6 1 0 0 1 1 1 0 HYD1 signature containing ADP-ribosyltransferase Ge1_WD40 PF16529.5 GAM25518.1 - 0.18 10.8 4.2 11 4.9 1.5 3.3 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FNIP PF05725.12 GAM25519.1 - 1.3e-65 217.4 37.7 8.8e-15 54.6 0.4 7.4 5 2 4 9 9 9 7 FNIP Repeat RRM_1 PF00076.22 GAM25520.1 - 2.8e-75 248.1 1.8 2.3e-17 62.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM25520.1 - 2.3e-09 36.9 0.0 0.043 13.4 0.0 4.4 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM25520.1 - 1.6e-07 31.0 0.1 0.072 13.0 0.0 4.7 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_7 PF16367.5 GAM25520.1 - 0.00018 21.5 0.0 28 4.9 0.0 5.2 5 0 0 5 5 5 0 RNA recognition motif Nup35_RRM_2 PF14605.6 GAM25520.1 - 0.0017 18.3 0.0 8.4 6.5 0.0 4.2 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.12 GAM25520.1 - 0.0083 16.3 0.8 35 4.7 0.0 3.7 3 0 0 3 3 3 0 RNA recognition motif 2 RNA_bind PF08675.11 GAM25520.1 - 0.037 14.1 0.2 2.9 8.0 0.0 3.6 4 0 0 4 4 4 0 RNA binding domain Limkain-b1 PF11608.8 GAM25520.1 - 0.13 12.4 0.1 5.7 7.1 0.0 3.7 4 0 0 4 4 4 0 Limkain b1 TMEM208_SND2 PF05620.11 GAM25520.1 - 0.66 9.7 3.0 0.84 9.4 0.4 2.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 zf-CCCH PF00642.24 GAM25521.1 - 3.8e-09 36.2 18.8 0.00011 22.0 5.0 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SAM_1 PF00536.30 GAM25521.1 - 3.7e-07 30.5 0.4 8.4e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) zf-CCCH_4 PF18044.1 GAM25521.1 - 3e-06 26.9 5.2 3e-06 26.9 5.2 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAM25521.1 - 4e-06 26.7 18.9 0.0015 18.5 7.3 2.9 2 1 0 2 2 2 2 Zinc finger domain SAM_2 PF07647.17 GAM25521.1 - 0.00011 22.2 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-CCCH_3 PF15663.5 GAM25521.1 - 0.00068 19.8 11.5 0.0081 16.4 2.2 2.7 3 0 0 3 3 3 2 Zinc-finger containing family Torus PF16131.5 GAM25521.1 - 0.00077 20.1 0.2 0.00077 20.1 0.2 3.0 3 1 1 4 4 3 1 Torus domain SUIM_assoc PF16619.5 GAM25521.1 - 0.006 16.6 1.6 0.006 16.6 1.6 3.7 2 1 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 zf-CCCH_2 PF14608.6 GAM25521.1 - 0.019 15.5 3.4 0.019 15.5 3.4 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TFIIA PF03153.13 GAM25521.1 - 0.025 14.6 25.2 0.034 14.1 25.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 GAM25521.1 - 0.57 8.7 10.4 0.64 8.5 2.4 2.0 2 0 0 2 2 2 0 Macoilin family Reovirus_cap PF00979.17 GAM25521.1 - 0.62 9.2 7.6 1.5 7.9 7.6 1.8 1 1 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 ANAPC_CDC26 PF10471.9 GAM25521.1 - 2.7 8.9 21.0 0.74 10.7 7.7 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Linker_histone PF00538.19 GAM25522.1 - 1.2e-20 73.6 1.6 2.6e-20 72.5 0.1 2.2 1 1 1 2 2 2 1 linker histone H1 and H5 family Forkhead PF00250.18 GAM25522.1 - 0.03 14.6 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 Forkhead domain Peptidase_C39_2 PF13529.6 GAM25522.1 - 0.042 14.4 1.1 0.042 14.4 1.1 1.8 1 1 0 2 2 2 0 Peptidase_C39 like family Phage_term_smal PF05944.12 GAM25522.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Phage small terminase subunit HC2 PF07382.11 GAM25522.1 - 0.46 10.5 65.5 2.1e+02 1.9 65.5 2.0 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 FAD_binding_6 PF00970.24 GAM25523.1 - 5.3e-35 119.7 0.0 8.8e-35 119.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAM25523.1 - 1.3e-28 99.8 0.0 2.2e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAM25523.1 - 1.5e-05 25.2 0.0 0.00021 21.4 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 GAM25523.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF2644 PF10841.8 GAM25523.1 - 0.11 12.7 0.7 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) Coiled PF05710.12 GAM25524.1 - 0.0085 16.9 14.2 0.023 15.5 14.2 1.6 1 1 0 1 1 1 1 Coiled coil Hus1 PF04005.12 GAM25525.1 - 2.3e-49 168.1 4.2 7.5e-49 166.4 4.2 1.7 1 1 0 1 1 1 1 Hus1-like protein DPBB_1 PF03330.18 GAM25527.1 - 1.2e-12 47.9 1.1 1.6e-11 44.3 0.1 3.1 3 1 0 3 3 3 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GAM25527.1 - 0.00019 21.4 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.17 GAM25527.1 - 0.014 15.2 0.3 0.057 13.3 0.1 2.1 1 1 1 2 2 2 0 Barwin family Cerato-platanin PF07249.12 GAM25527.1 - 0.015 15.4 0.7 0.034 14.3 0.7 1.6 1 0 0 1 1 1 0 Cerato-platanin V-SNARE_C PF12352.8 GAM25528.1 - 2.4e-08 34.1 1.1 6.5e-08 32.7 0.9 1.9 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Mucin PF01456.17 GAM25528.1 - 2.9e-05 24.1 40.0 2.9e-05 24.1 40.0 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein Sec20 PF03908.13 GAM25528.1 - 0.00041 20.2 0.6 0.00041 20.2 0.6 2.6 2 2 0 2 2 2 1 Sec20 SpoIIIAH PF12685.7 GAM25528.1 - 0.00055 19.8 0.7 0.00055 19.8 0.7 2.5 2 1 0 2 2 1 1 SpoIIIAH-like protein V-SNARE PF05008.15 GAM25528.1 - 0.011 16.1 3.3 0.011 16.1 3.3 2.6 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus CK2S PF15011.6 GAM25528.1 - 0.039 13.9 1.0 0.039 13.9 1.0 2.1 1 1 0 2 2 2 0 Casein Kinase 2 substrate LMP PF04778.12 GAM25528.1 - 0.13 12.2 12.1 0.14 12.0 11.0 1.6 1 1 1 2 2 2 0 LMP repeated region TcdB_N PF12918.7 GAM25528.1 - 0.22 11.8 10.3 2.9 8.2 0.8 2.9 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain TelA PF05816.11 GAM25528.1 - 0.23 10.5 13.2 0.89 8.6 2.3 2.5 2 1 0 2 2 2 0 Toxic anion resistance protein (TelA) Amnionless PF14828.6 GAM25528.1 - 0.31 9.8 5.7 0.1 11.4 1.6 1.8 1 1 1 2 2 2 0 Amnionless DUF3496 PF12001.8 GAM25528.1 - 0.51 10.7 6.5 0.89 10.0 5.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3496) APG6_N PF17675.1 GAM25528.1 - 1.3 9.6 14.8 4 8.0 7.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region YlqD PF11068.8 GAM25528.1 - 2.1 8.7 10.1 0.48 10.8 1.9 2.2 2 0 0 2 2 2 0 YlqD protein LAMTOR5 PF16672.5 GAM25529.1 - 7.9e-25 86.6 0.3 8.8e-25 86.5 0.3 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 RVT_3 PF13456.6 GAM25529.1 - 0.0017 18.2 0.0 0.0022 17.8 0.0 1.2 1 1 0 1 1 1 1 Reverse transcriptase-like ThiF PF00899.21 GAM25530.1 - 7.4e-65 218.7 0.1 1.1e-64 218.2 0.1 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 GAM25530.1 - 1.7e-24 85.8 0.0 2.6e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 GAM25530.1 - 0.0011 19.5 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 GAM25530.1 - 0.0056 16.7 0.2 0.018 15.1 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 GAM25530.1 - 0.021 14.8 2.0 0.43 10.5 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site DUF1967 PF09269.11 GAM25530.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) FeoA PF04023.14 GAM25530.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 FeoA domain Xin PF08043.12 GAM25530.1 - 0.15 11.7 0.9 0.32 10.7 0.9 1.5 1 0 0 1 1 1 0 Xin repeat eIF3_subunit PF08597.10 GAM25531.1 - 2.4e-41 142.2 21.9 2.7e-41 142.1 21.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Pox_A12 PF04651.13 GAM25531.1 - 0.056 13.5 0.7 0.056 13.5 0.7 1.9 2 0 0 2 2 2 0 Poxvirus A12 protein 7TM_GPCR_Srsx PF10320.9 GAM25532.1 - 5.4e-05 22.7 0.8 0.0001 21.8 0.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx FDC-SP PF15215.6 GAM25532.1 - 0.054 14.0 5.2 0.59 10.7 1.1 2.7 2 1 0 2 2 2 0 Follicular dendritic cell secreted peptide DUF5373 PF17343.2 GAM25532.1 - 0.57 10.0 6.6 0.088 12.6 2.8 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5373) RasGEF PF00617.19 GAM25533.1 - 3.8e-48 164.0 0.4 7.9e-48 163.0 0.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM25533.1 - 2.3e-08 34.2 0.3 2.3e-08 34.2 0.3 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif RhoGAP PF00620.27 GAM25533.1 - 2.6e-05 24.1 1.8 3.8e-05 23.6 0.0 2.2 3 0 0 3 3 3 1 RhoGAP domain Fib_alpha PF08702.10 GAM25533.1 - 0.024 14.8 3.9 0.093 12.9 3.2 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Lzipper-MIP1 PF14389.6 GAM25533.1 - 0.055 13.8 3.2 0.82 10.0 0.1 3.1 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 RPEL PF02755.15 GAM25533.1 - 0.065 13.0 0.2 0.22 11.3 0.2 2.0 1 0 0 1 1 1 0 RPEL repeat SlyX PF04102.12 GAM25533.1 - 0.074 13.7 8.6 4 8.1 0.6 3.0 1 1 1 2 2 2 0 SlyX CENP-F_leu_zip PF10473.9 GAM25533.1 - 0.09 12.8 9.8 0.8 9.7 2.2 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 GAM25533.1 - 0.1 11.9 3.9 0.3 10.4 3.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spectrin PF00435.21 GAM25533.1 - 0.16 12.5 1.9 4.4 7.8 1.2 2.9 2 1 0 2 2 2 0 Spectrin repeat CLZ PF16526.5 GAM25533.1 - 0.79 10.1 5.0 4.4 7.7 0.3 2.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 GAM25533.1 - 7 7.0 12.6 4.9 7.5 0.3 3.9 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RHD3 PF05879.12 GAM25534.1 - 1.8e-195 651.3 15.3 2.1e-195 651.1 15.3 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 GAM25534.1 - 2.9e-06 26.8 0.1 7.7e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 GAM25534.1 - 1e-05 25.6 0.0 5.1e-05 23.3 0.0 2.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAM25534.1 - 0.00061 19.9 2.2 0.0011 19.1 0.1 2.5 2 1 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 GAM25534.1 - 0.0041 17.4 0.5 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAM25534.1 - 0.027 14.5 0.0 0.1 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM25534.1 - 0.027 15.0 0.8 0.078 13.5 0.0 2.1 2 1 0 2 2 2 0 ABC transporter cwf21 PF08312.12 GAM25534.1 - 0.043 14.0 2.0 4.2 7.6 0.1 3.0 2 0 0 2 2 2 0 cwf21 domain AAA_16 PF13191.6 GAM25534.1 - 0.092 13.1 0.3 0.7 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Apolipoprotein PF01442.18 GAM25534.1 - 0.46 10.3 7.8 1.8 8.4 7.7 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CdiI_2 PF18593.1 GAM25534.1 - 3.2 8.5 7.7 1 10.1 0.3 3.6 4 0 0 4 4 3 0 CdiI immunity protein Mpv17_PMP22 PF04117.12 GAM25535.1 - 4.1e-21 75.0 2.0 4.1e-21 75.0 2.0 2.5 1 1 2 3 3 3 1 Mpv17 / PMP22 family TauE PF01925.19 GAM25535.1 - 0.041 13.5 2.0 0.067 12.8 1.6 1.6 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Caveolin PF01146.17 GAM25535.1 - 0.22 11.5 2.5 0.28 11.1 1.2 1.9 1 1 0 1 1 1 0 Caveolin RPAP1_C PF08620.10 GAM25536.1 - 1.7e-25 88.9 0.1 3.5e-25 87.9 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 GAM25536.1 - 1.8e-14 53.2 1.3 4.6e-14 51.9 1.3 1.8 1 0 0 1 1 1 1 RPAP1-like, N-terminal Acyl_transf_3 PF01757.22 GAM25537.1 - 4e-27 95.2 55.1 8.7e-27 94.1 52.5 2.1 2 0 0 2 2 2 2 Acyltransferase family FNIP PF05725.12 GAM25538.1 - 2.3e-58 194.1 17.1 1.1e-13 51.1 0.3 7.4 5 1 1 7 7 7 7 FNIP Repeat PI3_PI4_kinase PF00454.27 GAM25539.1 - 3.9e-60 203.8 0.1 1.2e-59 202.2 0.1 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAM25539.1 - 7.4e-56 188.5 0.3 7.4e-56 188.5 0.3 2.0 3 0 0 3 3 3 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_rbd PF00794.18 GAM25539.1 - 1.2e-22 80.1 3.4 1.8e-22 79.5 0.0 2.9 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 GAM25539.1 - 3.8e-18 65.8 0.0 3.8e-18 65.8 0.0 2.3 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 SR-25 PF10500.9 GAM25540.1 - 0.0037 16.9 3.1 0.009 15.7 3.1 1.7 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.7 GAM25541.1 - 0.19 11.5 9.1 0.33 10.7 9.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein RIFIN PF02009.16 GAM25541.1 - 0.32 10.8 0.9 0.51 10.2 0.9 1.2 1 0 0 1 1 1 0 Rifin SOG2 PF10428.9 GAM25541.1 - 1.8 7.7 20.1 2.7 7.1 20.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PP_M1 PF03012.14 GAM25541.1 - 7 6.1 5.7 11 5.5 5.7 1.2 1 0 0 1 1 1 0 Phosphoprotein Cullin PF00888.22 GAM25543.1 - 7.5e-165 550.0 22.7 9.1e-165 549.8 22.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAM25543.1 - 2.1e-26 91.8 0.4 2.1e-25 88.5 0.1 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain HbrB PF08539.11 GAM25543.1 - 8.2e-05 22.7 1.7 0.00039 20.5 0.2 2.6 2 0 0 2 2 2 1 HbrB-like RPA_C PF08784.11 GAM25543.1 - 0.038 14.7 0.0 2.1 9.1 0.0 2.7 2 0 0 2 2 2 0 Replication protein A C terminal HTH_24 PF13412.6 GAM25543.1 - 0.039 13.5 2.0 0.087 12.4 0.2 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DUF5105 PF17118.5 GAM25543.1 - 0.53 10.0 8.6 2 8.1 2.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5105) Pkinase PF00069.25 GAM25544.1 - 8.7e-55 185.9 0.0 1.5e-54 185.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25544.1 - 2.2e-22 79.6 0.0 8.7e-22 77.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GAM25544.1 - 0.00045 20.2 0.0 0.0035 17.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM25544.1 - 0.036 13.4 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM25544.1 - 0.059 13.0 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 RIO1 family Muted PF14942.6 GAM25545.1 - 3.3e-23 82.6 8.4 3.9e-23 82.4 8.4 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein SpoIISA_toxin PF14171.6 GAM25545.1 - 0.026 14.2 4.0 0.035 13.8 4.0 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system V_ATPase_I PF01496.19 GAM25545.1 - 0.67 7.8 6.3 0.79 7.6 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RabGAP-TBC PF00566.18 GAM25547.1 - 6.6e-28 97.8 15.2 2.5e-15 56.7 0.6 2.9 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Spt20 PF12090.8 GAM25548.1 - 4.3 6.9 18.5 4.4 6.9 18.5 1.0 1 0 0 1 1 1 0 Spt20 family Na_H_Exchanger PF00999.21 GAM25549.1 - 8.9e-50 169.6 42.4 8.2e-45 153.2 37.9 2.0 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family DUF4711 PF15829.5 GAM25549.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) TMEM164 PF14808.6 GAM25551.1 - 1.9e-06 27.4 10.0 1.3e-05 24.7 9.5 2.2 1 1 1 2 2 2 1 TMEM164 family Intg_mem_TP0381 PF09529.10 GAM25551.1 - 0.0012 18.4 24.7 0.0035 16.9 24.4 1.9 1 1 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) DUF2070 PF09843.9 GAM25551.1 - 7.7 4.7 9.1 25 3.0 9.0 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) RhoGEF PF00621.20 GAM25553.1 - 3.3e-49 167.6 3.2 5.4e-49 166.9 3.2 1.3 1 0 0 1 1 1 1 RhoGEF domain PSII_Pbs31 PF18240.1 GAM25553.1 - 0.087 13.3 0.5 19 5.8 0.0 2.7 2 0 0 2 2 2 0 Photosystem II Psb31 protein Med27 PF11571.8 GAM25554.1 - 9e-21 74.0 0.2 9e-21 74.0 0.2 2.3 2 0 0 2 2 2 1 Mediator complex subunit 27 DUF4471 PF14740.6 GAM25554.1 - 0.46 9.7 8.1 0.8 8.9 8.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4471) DUF3464 PF11947.8 GAM25554.1 - 0.67 9.7 6.5 1.4 8.6 6.5 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RR_TM4-6 PF06459.12 GAM25554.1 - 4.2 7.1 12.4 10 5.9 12.4 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.22 GAM25555.1 - 1.3e-49 165.9 11.4 1e-15 57.3 0.1 6.0 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM25555.1 - 1.6e-06 28.1 0.2 0.0076 16.3 0.0 4.4 4 0 0 4 4 4 2 RNA recognition motif SET_assoc PF11767.8 GAM25555.1 - 0.13 11.9 0.1 3 7.5 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Sulfotransfer_1 PF00685.27 GAM25556.1 - 2.3e-20 73.2 2.9 4.8e-19 68.9 2.9 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAM25556.1 - 2.9e-14 54.0 0.1 0.00083 19.8 0.0 3.3 2 1 1 3 3 3 3 Sulfotransferase family Sulfotransfer_2 PF03567.14 GAM25556.1 - 0.0063 16.4 0.2 0.023 14.6 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase family DUF3024 PF11225.8 GAM25556.1 - 0.034 14.4 3.2 4.4 7.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) PAF-AH_p_II PF03403.13 GAM25556.1 - 0.1 11.1 0.1 0.15 10.5 0.1 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF4805 PF16063.5 GAM25556.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) CLPTM1 PF05602.12 GAM25557.1 - 2.8e-132 441.8 9.1 4.1e-132 441.2 9.1 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 GAM25557.1 - 0.00042 20.0 1.0 0.14 11.9 0.2 2.9 2 1 0 2 2 2 2 PQ loop repeat PI-TkoII_IV PF18714.1 GAM25558.1 - 0.12 11.9 0.8 0.83 9.1 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase II intein Domain IV DUF809 PF05663.11 GAM25558.1 - 0.15 12.2 0.1 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF809) EGF_2 PF07974.13 GAM25559.1 - 0.0069 16.7 35.5 0.0081 16.5 7.6 3.2 3 0 0 3 3 3 2 EGF-like domain EGF PF00008.27 GAM25559.1 - 6.1 7.3 30.3 0.47 10.8 9.4 3.4 3 0 0 3 3 3 0 EGF-like domain Big_5 PF13205.6 GAM25559.1 - 8.9 7.1 12.4 0.28 11.9 1.5 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain Complex1_51K PF01512.17 GAM25560.1 - 6.8e-48 162.4 0.0 1.1e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 GAM25560.1 - 3.3e-29 100.8 0.0 6.7e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 GAM25560.1 - 7.1e-09 35.4 0.0 2.2e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 SLBB domain CorA PF01544.18 GAM25561.1 - 5.7e-46 157.2 2.1 5.7e-46 157.2 2.1 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein FH2 PF02181.23 GAM25562.1 - 2.1e-73 247.6 4.1 2.1e-73 247.6 4.1 2.5 3 0 0 3 3 3 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 GAM25562.1 - 1.1e-32 113.3 3.1 1.1e-32 113.3 3.1 2.1 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 GAM25562.1 - 7.2e-18 64.8 2.6 7.2e-18 64.8 2.6 2.9 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain C1_1 PF00130.22 GAM25562.1 - 4.2e-08 32.9 6.8 8e-08 32.1 6.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 GAM25562.1 - 0.022 15.1 5.5 0.045 14.1 5.5 1.5 1 0 0 1 1 1 0 C1 domain Fe_bilin_red PF05996.12 GAM25562.1 - 0.096 12.4 0.8 0.2 11.3 0.8 1.4 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase DNA_pol3_alpha PF07733.12 GAM25562.1 - 0.12 12.0 1.5 0.17 11.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha NTPase domain OrfB_Zn_ribbon PF07282.11 GAM25562.1 - 0.61 10.1 5.7 2 8.4 5.7 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Mu-like_Pro PF10123.9 GAM25562.1 - 0.62 9.6 9.0 0.41 10.2 1.3 2.4 2 0 0 2 2 2 0 Mu-like prophage I protein PHD PF00628.29 GAM25562.1 - 1.8 8.5 6.7 3.9 7.4 6.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 GAM25562.1 - 3.5 7.6 11.2 0.93 9.4 6.1 2.5 2 1 1 3 3 3 0 Putative zinc-RING and/or ribbon DUF3337 PF11816.8 GAM25563.1 - 3.1e-27 95.5 0.0 3.1e-27 95.5 0.0 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3337) WD40 PF00400.32 GAM25563.1 - 4.3e-26 90.7 24.0 0.00013 22.7 0.4 7.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM25563.1 - 5.9e-07 29.7 3.5 0.26 11.6 0.1 5.2 4 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain RAWUL PF16207.5 GAM25563.1 - 9.8e-05 23.0 0.2 0.00038 21.1 0.2 2.1 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like WD40_like PF17005.5 GAM25563.1 - 0.00026 20.4 0.7 0.0015 17.9 0.2 2.2 2 0 0 2 2 2 1 WD40-like domain TFIIA PF03153.13 GAM25563.1 - 0.15 12.0 76.5 0.26 11.3 15.3 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 GAM25563.1 - 0.25 11.2 44.3 0.24 11.3 11.5 3.3 3 0 0 3 3 3 0 SPX domain MMR_HSR1 PF01926.23 GAM25564.1 - 6e-21 74.7 0.1 6e-21 74.7 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM25564.1 - 4.7e-08 33.1 0.0 0.014 15.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAM25564.1 - 1.7e-05 24.4 0.0 2.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAM25564.1 - 0.00027 21.0 5.0 0.14 12.2 0.1 2.9 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 GAM25564.1 - 0.00031 20.4 0.0 0.0037 16.8 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAM25564.1 - 0.01 15.3 0.0 0.032 13.6 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 GAM25564.1 - 0.042 13.4 0.2 0.08 12.5 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 GAM25564.1 - 0.076 12.8 0.0 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain PseudoU_synth_2 PF00849.22 GAM25565.1 - 5.2e-30 104.6 0.1 7.3e-30 104.2 0.1 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Senescence PF06911.12 GAM25566.1 - 4.6e-23 82.5 3.4 6.5e-23 82.0 3.4 1.2 1 0 0 1 1 1 1 Senescence-associated protein PH PF00169.29 GAM25566.1 - 0.00011 22.7 0.1 0.00065 20.2 0.1 2.4 1 1 0 1 1 1 1 PH domain DUF1512 PF07431.12 GAM25566.1 - 0.035 13.1 0.1 0.054 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) AIM3 PF17096.5 GAM25566.1 - 5 8.1 6.3 1.8 9.6 0.7 2.4 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 SPRY PF00622.28 GAM25567.1 - 6.1e-15 55.4 4.5 4.1e-09 36.6 0.1 3.2 3 0 0 3 3 3 2 SPRY domain PHD PF00628.29 GAM25567.1 - 3.3e-07 30.1 7.4 7.2e-07 29.0 7.4 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 GAM25567.1 - 0.013 15.7 4.6 0.065 13.5 4.6 2.2 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_4 PF16866.5 GAM25567.1 - 0.017 15.2 4.5 0.063 13.4 4.5 2.0 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 GAM25567.1 - 0.047 14.0 7.2 0.092 13.1 3.9 2.4 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 GAM25567.1 - 0.28 11.1 6.9 0.044 13.7 2.6 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 GAM25567.1 - 0.6 10.3 7.4 0.48 10.6 3.6 2.5 1 1 0 2 2 2 0 PHD-zinc-finger like domain DZR PF12773.7 GAM25567.1 - 0.82 9.7 6.8 2.5 8.2 6.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF3716 PF12511.8 GAM25567.1 - 3.3 7.8 5.8 14 5.8 5.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) Zf_RING PF16744.5 GAM25567.1 - 4.3 7.5 10.1 0.63 10.2 4.1 2.6 2 1 1 3 3 3 0 KIAA1045 RING finger RNB PF00773.19 GAM25568.1 - 2.3e-99 332.8 0.0 4.9e-99 331.7 0.0 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GAM25568.1 - 9e-20 70.5 0.0 2.1e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 GAM25568.1 - 1.2e-05 25.0 0.1 1.2e-05 25.0 0.1 1.9 2 0 0 2 2 2 1 Rrp44-like cold shock domain Dis3l2_C_term PF17877.1 GAM25568.1 - 0.00012 22.3 0.0 0.00012 22.3 0.0 2.8 3 0 0 3 3 3 1 DIS3-like exonuclease 2 C terminal RRM_1 PF00076.22 GAM25569.1 - 2.4e-17 62.5 0.0 4.1e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 GAM25569.1 - 0.0084 15.9 0.1 0.022 14.5 0.1 1.9 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 GAM25569.1 - 0.046 13.7 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif V_ATPase_I PF01496.19 GAM25569.1 - 0.075 10.9 1.4 0.083 10.8 1.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PRKG1_interact PF15898.5 GAM25569.1 - 0.079 13.9 6.1 0.12 13.3 6.1 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain RL PF17797.1 GAM25569.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 RL domain Pkinase PF00069.25 GAM25570.1 - 2.5e-72 243.4 0.0 3.8e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25570.1 - 5.9e-41 140.5 0.0 9.7e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM25570.1 - 0.028 13.7 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GAM25570.1 - 0.052 13.5 4.0 0.14 12.0 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Glyco_hydro_18 PF00704.28 GAM25571.1 - 2.7e-11 43.8 2.1 3.9e-11 43.2 0.1 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 Peptidase_C1 PF00112.23 GAM25572.1 - 2.3e-70 237.1 4.2 3.2e-70 236.6 4.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM25572.1 - 1.5e-15 57.3 4.3 2.5e-15 56.6 4.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAM25572.1 - 4.6e-06 25.7 0.6 0.0024 16.7 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Coatomer_b_Cpla PF14806.6 GAM25572.1 - 0.15 12.1 0.2 0.35 10.8 0.2 1.6 1 1 0 1 1 1 0 Coatomer beta subunit appendage platform NSP11 PF06471.12 GAM25574.1 - 0.012 14.1 0.2 0.012 14.1 0.2 1.0 1 0 0 1 1 1 0 NSP11 LRR_4 PF12799.7 GAM25574.1 - 0.12 12.9 1.7 5.2 7.6 0.2 2.8 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) ORC5_C PF14630.6 GAM25575.1 - 2e-36 126.0 0.1 3.7e-36 125.1 0.1 1.4 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus DHR-2 PF06920.13 GAM25576.1 - 7.1e-90 302.1 15.1 7.1e-90 302.1 15.1 2.4 2 1 0 2 2 2 1 Dock homology region 2 DOCK_N PF16172.5 GAM25576.1 - 9.5e-73 245.3 0.2 2.7e-72 243.8 0.2 1.8 1 1 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 GAM25576.1 - 6.3e-41 140.3 4.6 1.2e-38 132.8 1.3 3.6 3 1 0 3 3 3 2 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 GAM25576.1 - 0.00045 20.0 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM25576.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain HATPase_c PF02518.26 GAM25577.1 - 3.7e-29 101.5 0.0 7.8e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM25577.1 - 6.6e-21 74.6 0.0 1.1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAM25577.1 - 1.1e-18 67.0 0.1 2e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain CitMHS PF03600.16 GAM25577.1 - 0.02 14.1 2.0 0.029 13.6 2.0 1.2 1 0 0 1 1 1 0 Citrate transporter RasGAP PF00616.19 GAM25578.1 - 1.2e-37 129.7 0.1 2.8e-24 86.0 0.0 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 GAM25578.1 - 2.2e-22 79.3 0.2 4.6e-22 78.2 0.2 1.6 1 0 0 1 1 1 1 C2 domain FF PF01846.19 GAM25579.1 - 1.6e-24 85.8 7.9 1.1e-07 31.9 0.3 5.5 5 0 0 5 5 5 3 FF domain WW PF00397.26 GAM25579.1 - 4.1e-22 78.0 11.9 7.5e-13 48.3 4.5 2.7 2 0 0 2 2 2 2 WW domain DUF3085 PF11284.8 GAM25579.1 - 0.0014 18.9 0.4 0.052 13.9 0.1 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3085) Glyco_hyd_101C PF17451.2 GAM25579.1 - 0.02 15.2 1.3 7.7 6.8 0.1 2.7 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain SNF2_N PF00176.23 GAM25580.1 - 6.3e-68 229.1 1.9 6.3e-68 229.1 1.9 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.24 GAM25580.1 - 9.7e-23 79.8 7.2 3.8e-13 49.1 0.8 3.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 GAM25580.1 - 5.1e-20 71.9 0.0 2.2e-19 69.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 GAM25580.1 - 5.7e-17 61.9 1.4 5.7e-17 61.9 1.4 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4208) ResIII PF04851.15 GAM25580.1 - 2e-09 37.7 0.0 2e-09 37.7 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 GAM25580.1 - 0.0076 16.9 0.2 0.0076 16.9 0.2 4.8 5 0 0 5 5 5 1 CDH1/2 SANT-Helical linker 1 Myb_DNA-binding PF00249.31 GAM25580.1 - 0.06 13.6 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain SLIDE PF09111.10 GAM25580.1 - 0.12 12.4 0.0 0.12 12.4 0.0 4.7 5 0 0 5 5 5 0 SLIDE UQ_con PF00179.26 GAM25581.1 - 4.7e-46 155.9 0.1 6.4e-46 155.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM25581.1 - 0.1 12.3 0.0 0.31 10.8 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 GAM25581.1 - 0.13 12.6 0.6 0.23 11.7 0.3 1.7 1 1 0 1 1 1 0 RWD domain Cwf_Cwc_15 PF04889.12 GAM25581.1 - 4.2 7.0 12.7 5.3 6.7 12.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 GAM25582.1 - 1.8e-10 41.2 8.0 0.3 12.0 0.1 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM25582.1 - 0.005 17.1 0.3 8.5 6.8 0.0 4.1 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain zf-RVT PF13966.6 GAM25583.1 - 0.071 13.8 0.9 0.082 13.6 0.9 1.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Ank_2 PF12796.7 GAM25584.1 - 3.9e-05 24.1 5.8 0.32 11.6 0.5 5.0 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM25585.1 - 0.028 14.7 0.1 5.9 7.3 0.0 3.9 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM25585.1 - 0.034 14.7 0.0 0.77 10.4 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM25585.1 - 0.1 13.2 0.0 1 10.0 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) VKOR PF07884.14 GAM25586.1 - 1.3e-17 64.2 15.0 1.3e-17 64.2 15.0 1.8 2 0 0 2 2 2 1 Vitamin K epoxide reductase family ILEI PF15711.5 GAM25587.1 - 9e-42 141.5 3.8 1.4e-14 54.3 0.2 3.4 3 0 0 3 3 3 3 Interleukin-like EMT inducer DUF99 PF01949.16 GAM25587.1 - 0.31 10.4 1.8 1.1 8.6 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF99 FNIP PF05725.12 GAM25588.1 - 4.9e-60 199.5 21.3 2.5e-15 56.3 0.8 5.8 6 0 0 6 6 6 5 FNIP Repeat Peptidase_M1 PF01433.20 GAM25589.1 - 1.6e-77 259.9 0.8 2.9e-77 259.1 0.8 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 GAM25589.1 - 2.4e-66 224.5 0.0 7.7e-66 222.8 0.0 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 GAM25589.1 - 1e-51 175.8 0.1 1.7e-51 175.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Neisseria_TspB PF05616.13 GAM25589.1 - 0.11 11.0 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein GST_N_2 PF13409.6 GAM25590.1 - 3.3e-20 72.2 0.0 8.2e-20 70.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM25590.1 - 8.1e-14 51.4 0.1 2.2e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM25590.1 - 1.9e-09 37.6 0.0 3.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM25590.1 - 3.2e-06 27.3 0.1 7.8e-06 26.0 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM25590.1 - 9.3e-05 22.8 0.0 0.00041 20.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAM25590.1 - 0.0012 18.5 0.1 0.0051 16.6 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.27 GAM25591.1 - 1.5e-74 246.0 0.1 8.2e-26 89.8 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GAM25591.1 - 9.6e-22 77.2 8.0 3.2e-06 27.5 0.3 4.6 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 GAM25591.1 - 7.1e-20 69.0 19.5 1.2e-05 24.5 0.2 6.4 8 0 0 8 8 8 4 EF hand EF-hand_6 PF13405.6 GAM25591.1 - 2.3e-17 61.4 21.4 9e-06 25.2 0.5 7.5 9 0 0 9 9 8 4 EF-hand domain EF-hand_8 PF13833.6 GAM25591.1 - 5.3e-13 48.6 9.3 0.0004 20.2 0.7 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 GAM25591.1 - 4.6e-11 41.7 15.7 0.00017 20.9 0.1 5.3 6 0 0 6 6 6 3 EF hand EF-hand_4 PF12763.7 GAM25591.1 - 0.00049 20.0 0.9 0.055 13.4 0.1 2.9 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 GAM25591.1 - 0.0033 17.7 0.0 1.9 8.9 0.0 3.9 3 1 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 GAM25591.1 - 0.015 15.6 0.9 2.1 8.7 0.0 3.1 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 GAM25591.1 - 0.017 15.9 0.1 16 6.5 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain DUF4044 PF13253.6 GAM25591.1 - 9.3 5.9 5.4 17 5.0 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4044) Na_Ca_ex PF01699.24 GAM25593.1 - 5.7e-24 84.8 32.4 5.9e-12 45.8 10.5 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Wzy_C PF04932.15 GAM25593.1 - 0.0099 15.5 6.3 0.025 14.2 0.8 2.9 2 1 0 2 2 2 1 O-Antigen ligase Pex24p PF06398.11 GAM25593.1 - 0.87 8.5 2.4 1.1 8.2 1.0 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF1129 PF06570.11 GAM25593.1 - 2.4 7.6 5.7 0.51 9.8 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1294 PF06961.13 GAM25594.1 - 6.3e-21 74.4 0.7 1.2e-20 73.4 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1294) TauE PF01925.19 GAM25594.1 - 0.005 16.5 0.0 0.0054 16.4 0.0 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE EOS1 PF12326.8 GAM25594.1 - 0.35 10.8 1.8 0.57 10.1 1.8 1.4 1 1 0 1 1 1 0 N-glycosylation protein LMBR1 PF04791.16 GAM25594.1 - 1.1 8.1 4.6 1.3 7.8 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Brix PF04427.18 GAM25595.1 - 9.5e-24 84.6 0.1 1.4e-23 84.0 0.1 1.3 1 0 0 1 1 1 1 Brix domain RhoGAP PF00620.27 GAM25596.1 - 1e-31 109.8 0.3 1e-30 106.6 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain RCC1_2 PF13540.6 GAM25596.1 - 4.6e-31 106.0 14.5 2.1e-06 27.4 0.1 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 GAM25596.1 - 8e-29 100.0 8.8 2.8e-10 40.6 0.0 8.6 8 2 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat ERM PF00769.19 GAM25596.1 - 0.31 10.8 7.0 0.52 10.1 7.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Neuraminidase PF18413.1 GAM25597.1 - 0.22 11.1 1.6 0.41 10.3 0.0 1.7 1 1 1 2 2 2 0 Neuraminidase-like domain NAD_binding_8 PF13450.6 GAM25598.1 - 4.7e-06 26.7 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAM25598.1 - 5.7e-05 22.6 0.0 9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 GAM25598.1 - 8.8e-05 21.9 0.0 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 GAM25598.1 - 0.00045 19.6 0.0 0.00075 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM25598.1 - 0.00062 19.1 0.0 0.044 13.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM25598.1 - 0.0018 18.0 0.1 0.29 10.7 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM25598.1 - 0.0091 15.1 0.2 0.037 13.1 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GAM25598.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 GAM25598.1 - 0.031 13.4 0.0 0.38 9.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GDI PF00996.18 GAM25598.1 - 0.042 12.4 0.0 0.085 11.4 0.0 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor Ank_2 PF12796.7 GAM25599.1 - 0.00051 20.6 0.0 0.052 14.1 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM25599.1 - 0.003 18.1 0.0 0.0082 16.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM25599.1 - 0.079 13.6 0.0 2.8 8.8 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 GAM25600.1 - 2.4e-80 265.2 33.4 3.5e-16 59.5 0.5 13.5 7 4 4 13 13 13 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM25600.1 - 9.6e-73 239.7 28.1 5.2e-09 36.5 0.0 19.4 15 4 7 22 22 21 17 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM25600.1 - 9.9e-65 213.8 27.7 1.9e-07 31.2 0.0 18.3 14 3 6 21 21 20 13 Ankyrin repeats (many copies) PARP PF00644.20 GAM25600.1 - 1.4e-57 194.4 0.0 3e-57 193.4 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ank PF00023.30 GAM25600.1 - 7e-50 165.4 27.3 0.0023 18.3 0.3 20.5 21 0 0 21 21 20 12 Ankyrin repeat Ank_3 PF13606.6 GAM25600.1 - 1e-48 157.6 18.7 0.00068 19.9 0.0 18.8 20 0 0 20 20 19 10 Ankyrin repeat PARP_reg PF02877.14 GAM25600.1 - 4.5e-32 111.0 3.4 1.4e-31 109.4 2.7 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 GAM25600.1 - 1.6e-14 53.7 0.3 5.5e-14 52.0 0.2 2.1 2 0 0 2 2 2 1 WGR domain Nop14 PF04147.12 GAM25600.1 - 0.026 12.7 12.0 0.045 12.0 12.0 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GAM25600.1 - 0.46 9.8 9.5 0.84 8.9 9.5 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 GAM25600.1 - 4.5 6.6 12.9 7.9 5.8 12.9 1.3 1 0 0 1 1 1 0 SDA1 B56 PF01603.20 GAM25601.1 - 2.6e-159 530.7 6.4 3.2e-159 530.4 6.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cyclin PF08613.11 GAM25602.1 - 4.8e-35 121.3 0.1 4.8e-35 121.3 0.1 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAM25602.1 - 7.2e-11 41.9 0.0 1.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Beta-lactamase PF00144.24 GAM25603.1 - 2.5e-41 142.0 0.0 3.3e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 GAM25603.1 - 0.058 12.8 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Methyltransf_11 PF08241.12 GAM25604.1 - 3.1e-15 56.6 0.0 4.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM25604.1 - 3.3e-15 56.6 0.0 4.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM25604.1 - 7.3e-15 55.2 0.0 8.7e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM25604.1 - 2.5e-14 53.3 0.0 3.1e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM25604.1 - 1.2e-13 51.6 0.0 1.8e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAM25604.1 - 1.3e-05 24.3 0.1 1.9e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 GAM25604.1 - 4.5e-05 23.1 0.0 6.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 GAM25604.1 - 6.4e-05 22.2 0.0 8.8e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 GAM25604.1 - 6.6e-05 22.6 0.0 9.3e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 GAM25604.1 - 0.00011 21.7 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 GAM25604.1 - 0.00072 19.1 0.0 0.00099 18.7 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.14 GAM25604.1 - 0.0025 17.3 0.1 0.01 15.3 0.1 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 GAM25604.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family P63C PF10546.9 GAM25604.1 - 0.028 15.0 0.0 0.077 13.6 0.0 1.7 1 0 0 1 1 1 0 P63C domain PrmA PF06325.13 GAM25604.1 - 0.028 13.8 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 GAM25604.1 - 0.049 13.6 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SHR-BD PF06650.12 GAM25605.1 - 6.7e-40 137.2 0.5 6.7e-40 137.2 0.5 3.1 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 GAM25605.1 - 1.3e-35 122.8 12.1 2.7e-32 112.0 1.1 4.5 3 1 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 GAM25605.1 - 0.00014 22.1 0.0 0.00041 20.6 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 GAM25606.1 - 4.2e-58 196.9 4.8 4.2e-58 196.9 4.8 5.2 5 1 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 GAM25606.1 - 1e-55 188.7 15.9 3.6e-49 167.3 2.8 4.3 4 0 0 4 4 4 3 Repeating coiled region of VPS13 Chorein_N PF12624.7 GAM25606.1 - 6.6e-35 119.7 1.2 6.6e-35 119.7 1.2 2.7 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 YqzE PF14038.6 GAM25606.1 - 0.36 10.9 0.0 0.36 10.9 0.0 2.8 3 0 0 3 3 3 0 YqzE-like protein ARF7EP_C PF14949.6 GAM25606.1 - 3.7 8.2 5.8 2.7 8.6 0.1 3.5 3 0 0 3 3 3 0 ARF7 effector protein C-terminus 2-ph_phosp PF04029.14 GAM25607.1 - 1.2e-67 227.4 0.4 1.5e-67 227.1 0.4 1.0 1 0 0 1 1 1 1 2-phosphosulpholactate phosphatase HMGL-like PF00682.19 GAM25607.1 - 0.014 15.0 0.1 0.035 13.7 0.0 1.7 2 0 0 2 2 2 0 HMGL-like Pkinase PF00069.25 GAM25608.1 - 3.9e-67 226.4 0.0 5.2e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25608.1 - 2.1e-49 168.2 0.0 3.3e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1241 PF06840.11 GAM25608.1 - 2.8e-06 27.1 0.1 7.3e-06 25.7 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) Pkinase_fungal PF17667.1 GAM25608.1 - 0.0001 21.3 0.0 0.00017 20.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAM25608.1 - 0.00029 20.3 0.0 0.0094 15.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAM25608.1 - 0.0097 14.9 0.1 0.36 9.7 0.1 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Rib_recp_KP_reg PF05104.12 GAM25608.1 - 3.7 8.6 11.5 8.6 7.4 11.5 1.7 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Pkinase PF00069.25 GAM25609.1 - 9.5e-24 84.2 1.0 1.3e-19 70.6 0.4 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25609.1 - 1.5e-15 57.2 2.2 3.2e-12 46.3 0.5 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Cofilin_ADF PF00241.20 GAM25610.1 - 2.8e-33 114.3 0.4 3.1e-33 114.2 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SRP-alpha_N PF04086.13 GAM25611.1 - 0.59 10.0 35.8 0.67 9.8 35.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3246 PF11596.8 GAM25611.1 - 5.9 6.2 17.9 0.11 11.9 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) RRM_1 PF00076.22 GAM25612.1 - 1.2e-27 95.5 0.4 1.5e-14 53.5 0.1 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM25612.1 - 9.7e-09 35.0 0.1 1.8e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif zf-C3HC4_3 PF13920.6 GAM25612.1 - 0.00022 21.0 9.7 0.00036 20.3 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM25612.1 - 0.03 14.2 9.5 0.063 13.2 9.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM25612.1 - 0.07 13.0 6.1 0.16 11.9 6.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM25612.1 - 0.11 12.4 7.4 0.25 11.2 7.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAM25612.1 - 0.72 9.9 6.9 1.9 8.6 6.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 GAM25612.1 - 2.3 8.3 9.1 5.2 7.1 9.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAM25612.1 - 4.9 7.4 8.0 12 6.2 8.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GAM25612.1 - 7.8 6.9 9.3 14 6.1 9.3 1.5 1 0 0 1 1 1 0 Ring finger domain Tau95 PF09734.9 GAM25613.1 - 3.8e-25 89.3 3.2 9.7e-25 88.0 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 GAM25613.1 - 1.7e-19 70.2 2.3 1.8e-18 67.0 0.0 3.2 2 1 0 2 2 2 1 Tau95 Triple barrel domain DUF883 PF05957.13 GAM25613.1 - 0.7 10.5 4.7 2.2 9.0 4.7 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4770 PF15994.5 GAM25613.1 - 3.9 7.7 7.8 11 6.2 7.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) VPS13 PF16908.5 GAM25614.1 - 5.8e-48 163.7 10.8 2e-45 155.4 4.4 3.3 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 GAM25614.1 - 6e-47 159.7 1.5 6e-47 159.7 1.5 2.9 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 GAM25614.1 - 8.9e-44 149.9 0.1 1.9e-41 142.2 0.0 3.3 2 2 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 GAM25614.1 - 1.2e-19 70.5 0.2 1.2e-19 70.5 0.2 2.5 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 GAM25614.1 - 2.3e-19 69.8 18.7 5.9e-18 65.1 0.7 5.9 5 0 0 5 5 5 2 Repeating coiled region of VPS13 ATG_C PF09333.11 GAM25614.1 - 0.0007 19.9 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Cache_3-Cache_2 PF17201.4 GAM25614.1 - 0.15 11.3 0.5 0.31 10.3 0.5 1.5 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain CS PF04969.16 GAM25615.1 - 8.5e-08 33.1 0.9 1.2e-07 32.6 0.1 1.6 2 0 0 2 2 2 1 CS domain Annexin PF00191.20 GAM25615.1 - 0.22 11.6 2.8 2.3 8.4 0.0 2.7 3 0 0 3 3 3 0 Annexin RAI16-like PF10257.9 GAM25616.1 - 3.7e-79 266.2 5.1 5.9e-79 265.5 5.1 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein FPL PF09758.9 GAM25616.1 - 0.0015 18.6 0.0 0.1 12.6 0.0 2.8 2 0 0 2 2 2 1 Uncharacterised conserved protein GCIP PF13324.6 GAM25616.1 - 0.098 12.2 3.8 0.25 10.9 3.8 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Kelch_6 PF13964.6 GAM25617.1 - 2.1e-06 27.8 4.5 8.1e-06 25.9 0.1 3.3 3 2 1 4 4 4 1 Kelch motif Kelch_1 PF01344.25 GAM25617.1 - 4.9e-05 22.8 4.1 0.00029 20.3 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 GAM25617.1 - 0.0011 18.9 0.1 0.0011 18.9 0.1 3.3 5 1 1 6 6 6 1 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM25617.1 - 0.0013 18.9 4.2 0.0014 18.8 0.0 2.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM25617.1 - 0.0034 17.3 0.5 0.15 12.1 0.0 3.2 2 1 1 3 3 3 1 Kelch motif DUF5107 PF17128.4 GAM25617.1 - 0.042 13.0 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5107) Kelch_5 PF13854.6 GAM25617.1 - 0.055 13.5 2.0 1.2 9.2 0.1 2.9 3 1 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 GAM25618.1 - 4.4e-07 30.0 6.3 0.11 12.8 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 GAM25618.1 - 2.1e-06 27.6 6.0 0.0017 18.3 0.1 4.1 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM25618.1 - 0.00018 21.7 3.0 2 8.8 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM25618.1 - 0.016 14.8 7.6 0.22 11.1 0.5 3.3 4 0 0 4 4 4 0 Kelch motif Nup160 PF11715.8 GAM25618.1 - 0.02 13.6 0.0 0.037 12.7 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Kelch_2 PF07646.15 GAM25618.1 - 0.021 14.8 3.3 1.2 9.2 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.6 GAM25618.1 - 0.11 12.5 9.5 0.22 11.6 0.8 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 GAM25619.1 - 0.032 14.2 0.1 0.091 12.8 0.1 1.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM25619.1 - 0.06 13.7 0.6 0.34 11.3 0.4 1.9 1 1 1 2 2 2 0 Kelch motif Kelch_5 PF13854.6 GAM25619.1 - 0.067 13.2 0.4 0.11 12.5 0.4 1.3 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.6 GAM25620.1 - 0.026 14.8 1.1 5.8 7.4 0.0 2.6 1 1 1 2 2 2 0 Kelch motif Kelch_4 PF13418.6 GAM25620.1 - 0.2 11.7 0.7 38 4.4 0.2 3.4 3 1 0 3 3 3 0 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM25622.1 - 0.017 15.4 7.0 1.1 9.7 0.1 5.2 5 1 1 6 6 6 0 Kelch motif FliT PF05400.13 GAM25622.1 - 0.03 15.1 0.4 0.073 13.9 0.0 1.8 2 0 0 2 2 2 0 Flagellar protein FliT Kelch_5 PF13854.6 GAM25622.1 - 1.7 8.7 4.8 30 4.7 0.1 3.5 3 0 0 3 3 3 0 Kelch motif zf-B_box PF00643.24 GAM25623.1 - 7.2e-07 29.3 5.2 2.3e-06 27.7 5.2 1.8 1 0 0 1 1 1 1 B-box zinc finger Kelch_6 PF13964.6 GAM25623.1 - 0.0024 18.1 6.7 0.027 14.8 0.6 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 GAM25623.1 - 0.013 15.1 1.3 0.03 13.9 0.2 2.2 3 0 0 3 3 3 0 Kelch motif RPW8 PF05659.11 GAM25623.1 - 0.38 10.4 2.5 1.6 8.4 1.3 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Kelch_2 PF07646.15 GAM25623.1 - 0.64 10.1 2.4 1.6 8.8 0.3 2.6 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 GAM25624.1 - 1.7e-10 40.8 1.4 0.0028 17.9 0.0 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM25624.1 - 3.8e-10 39.6 5.5 2e-06 27.7 0.3 3.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM25624.1 - 1.8e-06 28.1 1.1 0.0023 18.2 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM25624.1 - 1.2e-05 24.8 0.2 1.2e-05 24.8 0.2 3.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 GAM25624.1 - 2.2e-05 24.2 4.0 0.37 10.8 0.0 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 GAM25624.1 - 0.015 15.3 6.1 0.81 9.7 0.4 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.25 GAM25625.1 - 3.6e-06 26.5 0.4 5.1e-05 22.8 0.0 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 GAM25625.1 - 0.0001 22.5 0.4 0.0019 18.5 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM25625.1 - 0.0092 16.2 0.6 0.31 11.4 0.0 3.2 3 1 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 GAM25625.1 - 0.062 13.3 0.0 0.062 13.3 0.0 3.2 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM25625.1 - 0.28 11.2 1.5 0.58 10.2 0.1 2.2 2 0 0 2 2 2 0 Kelch motif Peptidase_M16_C PF05193.21 GAM25627.1 - 3.9e-25 88.9 0.3 5.6e-24 85.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAM25627.1 - 1.2e-15 57.8 0.0 2.3e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) zf-PARP PF00645.18 GAM25628.1 - 2.5e-19 69.9 1.2 5.6e-19 68.8 0.2 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.9 GAM25628.1 - 1.4e-10 40.9 1.5 3e-10 39.9 1.5 1.6 1 0 0 1 1 1 1 PBZ domain FHA_2 PF17913.1 GAM25628.1 - 2.1e-07 31.1 0.1 5.1e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 FHA domain UDG PF03167.19 GAM25628.1 - 4e-06 26.9 0.0 8.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily FHA PF00498.26 GAM25628.1 - 0.0036 17.6 0.0 0.0095 16.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain Ribosomal_L1 PF00687.21 GAM25628.1 - 0.039 13.7 0.1 0.039 13.7 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L1p/L10e family BROMI PF14961.6 GAM25628.1 - 0.2 9.0 0.7 0.28 8.5 0.7 1.1 1 0 0 1 1 1 0 Broad-minded protein DUF908 PF06012.12 GAM25628.1 - 0.89 8.9 8.2 0.18 11.2 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DUF5523 PF17661.1 GAM25628.1 - 4.8 6.8 18.8 0.41 10.3 9.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Presenilin PF01080.17 GAM25628.1 - 6.7 5.4 8.8 1.7 7.4 1.8 2.1 2 0 0 2 2 2 0 Presenilin Ubie_methyltran PF01209.18 GAM25629.1 - 1.1e-90 303.1 0.0 1.3e-90 302.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAM25629.1 - 2.7e-13 50.4 0.0 4.8e-12 46.4 0.0 2.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM25629.1 - 3.6e-13 50.0 0.0 2.7e-12 47.2 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM25629.1 - 2.2e-09 37.3 0.0 9.7e-09 35.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM25629.1 - 3.1e-06 27.8 0.0 7.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM25629.1 - 9.8e-06 25.5 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 GAM25629.1 - 0.0011 18.9 0.0 0.0045 16.9 0.0 1.8 2 0 0 2 2 2 1 Hypothetical methyltransferase PhyH PF05721.13 GAM25630.1 - 1.8e-07 31.6 0.0 2.3e-06 28.1 0.0 2.4 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 GAM25630.1 - 4.4e-05 22.4 0.3 0.31 9.8 0.1 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) DUF3439 PF11921.8 GAM25630.1 - 0.79 9.7 16.3 1.4 8.9 16.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FNIP PF05725.12 GAM25631.1 - 1e-11 44.8 4.4 0.0034 17.5 0.0 6.5 2 1 3 6 6 6 5 FNIP Repeat LRR_8 PF13855.6 GAM25631.1 - 0.085 12.6 1.5 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Leucine rich repeat TIG PF01833.24 GAM25632.1 - 0.00064 19.7 3.6 0.00064 19.7 3.6 3.2 3 1 0 3 3 3 1 IPT/TIG domain SKG6 PF08693.10 GAM25632.1 - 0.0026 17.1 4.8 0.0026 17.1 4.8 2.3 3 0 0 3 3 3 1 Transmembrane alpha-helix domain EGF_2 PF07974.13 GAM25632.1 - 0.066 13.6 15.2 0.17 12.3 15.2 1.7 1 0 0 1 1 1 0 EGF-like domain DUF3827 PF12877.7 GAM25632.1 - 0.15 10.4 0.7 0.21 10.0 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TMEM154 PF15102.6 GAM25632.1 - 1.4 8.8 3.6 0.59 10.0 0.1 2.1 2 1 0 2 2 2 0 TMEM154 protein family LRR_1 PF00560.33 GAM25633.1 - 1.2 9.9 3.2 55 4.9 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 GAM25633.1 - 3.8 8.1 13.5 18 5.9 0.6 4.8 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) THUMP PF02926.17 GAM25634.1 - 3.3e-12 46.7 1.6 6.2e-12 45.8 1.6 1.4 1 0 0 1 1 1 1 THUMP domain SSP160 PF06933.11 GAM25634.1 - 0.00021 19.7 4.3 0.00028 19.2 4.3 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF1433 PF07252.11 GAM25634.1 - 0.092 13.0 0.5 0.28 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1433) DUF3439 PF11921.8 GAM25634.1 - 1.5 8.8 13.7 0.25 11.3 9.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Pex14_N PF04695.13 GAM25634.1 - 5.7 7.6 16.4 12 6.5 1.2 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EF-hand_1 PF00036.32 GAM25635.1 - 1e-15 56.0 8.2 4.1e-06 26.0 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 GAM25635.1 - 4e-15 54.4 6.9 2e-05 24.1 0.1 4.0 4 0 0 4 4 3 3 EF-hand domain EF-hand_7 PF13499.6 GAM25635.1 - 9.8e-12 45.2 2.5 1.6e-09 38.1 0.8 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GAM25635.1 - 5e-11 42.3 3.4 1.7e-09 37.4 1.2 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM25635.1 - 4.4e-08 32.3 4.7 0.00016 21.0 0.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 GAM25635.1 - 0.0019 18.5 0.0 0.029 14.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain YL1 PF05764.13 GAM25635.1 - 0.013 15.6 18.3 0.02 15.0 18.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NESP55 PF06390.12 GAM25635.1 - 0.068 12.8 8.6 0.095 12.3 8.6 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Mucin PF01456.17 GAM25635.1 - 0.11 12.4 17.6 0.17 11.9 17.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein FtsH_ext PF06480.15 GAM25635.1 - 0.17 12.3 6.9 0.52 10.7 6.8 2.0 1 1 0 1 1 1 0 FtsH Extracellular MAP65_ASE1 PF03999.12 GAM25635.1 - 0.2 10.3 12.4 0.26 9.9 12.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Macoilin PF09726.9 GAM25635.1 - 0.28 9.7 13.0 0.28 9.7 13.0 1.1 1 0 0 1 1 1 0 Macoilin family AJAP1_PANP_C PF15298.6 GAM25635.1 - 0.34 11.1 12.3 0.54 10.4 12.3 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus NUDE_C PF04880.13 GAM25635.1 - 0.35 11.3 11.3 0.56 10.7 11.3 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Ndc1_Nup PF09531.10 GAM25635.1 - 0.64 8.6 9.3 0.72 8.5 9.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 GAM25635.1 - 0.92 9.0 12.7 1.3 8.5 12.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 GAM25635.1 - 1.3 7.2 14.3 1.7 6.9 14.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Rad33 PF08730.10 GAM25635.1 - 2 8.4 0.0 2 8.4 0.0 3.2 3 1 1 4 4 3 0 Rad33 CENP-U PF13097.6 GAM25635.1 - 3.6 7.5 17.5 5.6 6.9 17.5 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Hid1 PF12722.7 GAM25635.1 - 4.3 5.3 10.6 5.4 5.0 10.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Roughex PF06020.11 GAM25635.1 - 4.6 6.2 13.5 6.4 5.8 13.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TraF PF13728.6 GAM25635.1 - 7.2 6.4 9.1 10 5.9 8.3 1.6 2 0 0 2 2 2 0 F plasmid transfer operon protein RRN3 PF05327.11 GAM25635.1 - 9.4 4.6 12.6 14 4.1 12.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Phosphodiest PF01663.22 GAM25636.1 - 5.1e-11 42.8 0.5 1.3e-10 41.5 0.5 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAM25636.1 - 7e-06 25.6 0.2 7e-06 25.6 0.2 1.5 2 0 0 2 2 2 1 Sulfatase ATP_bind_1 PF03029.17 GAM25637.1 - 1.5e-69 234.5 0.7 1.9e-69 234.1 0.7 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ATLF PF07737.11 GAM25637.1 - 0.0078 15.5 0.6 0.012 14.9 0.6 1.3 1 0 0 1 1 1 1 Anthrax toxin lethal factor, N- and C-terminal domain DASH_Dad4 PF08650.10 GAM25637.1 - 0.093 12.7 1.7 0.28 11.2 1.7 1.9 1 0 0 1 1 1 0 DASH complex subunit Dad4 AAA_31 PF13614.6 GAM25637.1 - 0.094 12.6 0.4 11 5.9 0.0 2.6 2 1 0 3 3 3 0 AAA domain GFA PF04828.14 GAM25638.1 - 1.8e-08 34.6 2.0 1.8e-08 34.6 2.0 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ank_2 PF12796.7 GAM25639.1 - 1.7e-10 41.3 5.7 0.021 15.4 0.2 5.3 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM25639.1 - 3.8e-07 30.3 1.1 0.23 11.8 0.0 6.0 7 1 0 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM25639.1 - 4.7e-05 23.5 6.0 0.046 14.3 0.0 6.7 8 0 0 8 8 8 1 Ankyrin repeat Ank_4 PF13637.6 GAM25639.1 - 0.0097 16.5 4.0 3.2 8.4 0.0 5.0 5 2 0 5 5 5 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 GAM25639.1 - 0.057 13.4 1.2 1.6 8.8 0.6 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) ATG19_autophagy PF12744.7 GAM25640.1 - 0.017 14.3 0.3 0.064 12.4 0.7 1.7 2 0 0 2 2 2 0 Autophagy protein Atg19, Atg8-binding EGF PF00008.27 GAM25640.1 - 0.055 13.8 4.8 0.13 12.6 4.8 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 GAM25640.1 - 0.098 13.3 9.7 0.33 11.7 9.7 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF MBG PF17883.1 GAM25640.1 - 0.16 12.5 10.9 0.057 14.0 1.1 4.1 3 0 0 3 3 3 0 MBG domain LapA_dom PF06305.11 GAM25640.1 - 0.18 11.7 0.8 0.48 10.3 0.8 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EGF_2 PF07974.13 GAM25640.1 - 0.18 12.2 9.9 0.026 14.9 5.6 1.9 2 0 0 2 2 2 0 EGF-like domain Lectin_C PF00059.21 GAM25641.1 - 0.0055 17.4 0.0 0.015 16.0 0.0 1.8 1 0 0 1 1 1 1 Lectin C-type domain CCDC84 PF14968.6 GAM25641.1 - 0.01 15.5 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 DUF749 PF05370.11 GAM25641.1 - 0.076 13.1 0.8 2.6 8.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF749) DNA_ligase_A_C PF04679.15 GAM25642.1 - 1.8e-27 95.9 0.0 2.2e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 GAM25642.1 - 1.6e-05 24.9 0.3 0.0075 16.3 0.0 2.3 2 0 0 2 2 2 2 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 GAM25643.1 - 7e-57 192.4 1.2 9.9e-56 188.6 0.0 2.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAM25643.1 - 1.1e-43 149.6 0.2 3.1e-43 148.1 0.2 1.8 1 0 0 1 1 1 1 DNA ligase N terminus Merozoite_SPAM PF07133.11 GAM25643.1 - 0.053 13.5 48.0 0.24 11.4 19.6 2.5 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) MCM6_C PF18263.1 GAM25643.1 - 2.2 8.6 11.4 0.031 14.5 3.3 2.2 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain RRM_1 PF00076.22 GAM25644.1 - 3.3e-29 100.5 0.0 3e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM25644.1 - 0.00043 20.3 0.0 0.0011 19.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 GAM25644.1 - 0.017 14.7 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 GAM25644.1 - 0.14 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain zf-CDGSH PF09360.10 GAM25645.1 - 1.6e-21 76.2 2.6 8.2e-10 38.8 0.1 2.5 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type MRF_C2 PF13888.6 GAM25645.1 - 0.036 14.0 0.7 0.081 12.8 0.9 1.5 1 1 1 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 DUF4505 PF14956.6 GAM25645.1 - 0.043 13.6 3.6 0.13 12.0 2.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4505) PH PF00169.29 GAM25646.1 - 5e-25 88.0 4.4 2e-12 47.6 0.2 2.5 2 0 0 2 2 2 2 PH domain FHA PF00498.26 GAM25646.1 - 3.9e-16 59.2 0.4 1.2e-15 57.6 0.4 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAM25646.1 - 3.9e-14 52.7 0.0 9.8e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PH_11 PF15413.6 GAM25646.1 - 3.2e-09 37.2 9.6 0.00049 20.5 2.1 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 GAM25646.1 - 4.4e-06 26.9 3.5 0.011 16.0 1.9 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 GAM25646.1 - 0.0019 18.5 4.1 1.7 9.0 0.1 4.1 3 2 0 3 3 3 1 Pleckstrin homology domain DUF4905 PF16248.5 GAM25646.1 - 0.08 12.8 2.6 1.8 8.5 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4905) LRR_6 PF13516.6 GAM25647.1 - 2.6e-15 55.1 18.3 0.3 11.2 0.0 13.6 16 0 0 16 16 16 4 Leucine Rich repeat LRR_4 PF12799.7 GAM25647.1 - 4.5e-15 55.5 21.2 0.017 15.5 1.1 10.8 9 3 2 12 12 12 5 Leucine Rich repeats (2 copies) ABC_tran PF00005.27 GAM25647.1 - 0.01 16.3 0.0 0.034 14.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 GAM25647.1 - 0.021 14.6 0.2 0.07 12.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 GAM25647.1 - 0.022 15.2 0.1 0.087 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 GAM25647.1 - 0.068 12.5 0.4 7.5 5.8 0.2 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family SAM_Ste50p PF09235.10 GAM25647.1 - 0.22 11.8 4.8 42 4.5 0.2 4.6 3 1 1 4 4 4 0 Ste50p, sterile alpha motif LRR_1 PF00560.33 GAM25647.1 - 2.1 9.2 23.4 1e+02 4.1 0.5 11.1 12 1 0 12 12 12 0 Leucine Rich Repeat SUIM_assoc PF16619.5 GAM25647.1 - 9.6 6.4 7.2 50 4.1 2.8 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Guanylate_kin PF00625.21 GAM25648.1 - 6.9e-56 188.8 0.0 8.3e-56 188.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 GAM25648.1 - 2.5e-05 24.8 0.2 7.3e-05 23.3 0.2 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAM25648.1 - 0.0008 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 GAM25648.1 - 0.00085 19.4 0.0 0.0016 18.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 GAM25648.1 - 0.0015 18.9 0.0 0.0016 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM25648.1 - 0.0075 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAM25648.1 - 0.0076 16.8 0.3 0.019 15.5 0.3 1.9 1 1 0 1 1 1 1 ABC transporter dNK PF01712.19 GAM25648.1 - 0.0097 15.8 0.1 0.62 9.9 0.1 2.3 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_28 PF13521.6 GAM25648.1 - 0.011 15.9 0.0 0.023 15.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAM25648.1 - 0.012 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.6 GAM25648.1 - 0.013 16.0 0.1 0.33 11.4 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAM25648.1 - 0.013 15.6 0.2 0.21 11.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAM25648.1 - 0.039 13.7 0.1 0.074 12.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 GAM25648.1 - 0.057 13.0 0.2 0.13 11.9 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.17 GAM25648.1 - 0.075 12.7 0.1 13 5.4 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase PRK PF00485.18 GAM25648.1 - 0.08 12.7 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ADK PF00406.22 GAM25648.1 - 0.1 12.7 0.1 3.1 7.9 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase RNA_helicase PF00910.22 GAM25648.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 GAM25648.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.2 1 1 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 GAM25648.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Foie-gras_1 PF11817.8 GAM25649.1 - 3.2e-09 36.8 0.1 1.6e-07 31.2 0.0 2.8 2 1 0 2 2 2 1 Foie gras liver health family 1 TRAPPC10 PF12584.8 GAM25649.1 - 3.8e-09 36.4 0.0 1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Goodbye PF17109.5 GAM25649.1 - 0.052 14.0 0.1 0.16 12.4 0.1 1.8 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Serglycin PF04360.12 GAM25649.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Serglycin RPN7 PF10602.9 GAM25649.1 - 0.21 11.3 4.0 0.078 12.7 0.9 1.9 2 0 0 2 2 2 0 26S proteasome subunit RPN7 DUF4602 PF15375.6 GAM25650.1 - 0.00011 22.5 12.6 0.00011 22.5 12.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4602) Exo_endo_phos PF03372.23 GAM25651.1 - 3.1e-10 40.0 0.0 4.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CBM49 PF09478.10 GAM25652.1 - 2.2e-07 31.1 2.3 5e-07 29.9 2.3 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Tup_N PF08581.10 GAM25652.1 - 0.41 11.0 5.1 0.9 9.9 1.8 2.7 2 1 1 3 3 3 0 Tup N-terminal ERM PF00769.19 GAM25652.1 - 0.54 10.0 28.1 5.2 6.8 24.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CH_2 PF06294.11 GAM25652.1 - 0.58 10.3 3.9 1.8 8.7 0.1 3.1 3 1 1 4 4 4 0 CH-like domain in sperm protein CBM49 PF09478.10 GAM25653.1 - 0.022 15.1 0.8 0.059 13.7 0.1 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain CBM49 Alanine_zipper PF11839.8 GAM25653.1 - 0.7 10.3 40.2 0.084 13.2 9.4 3.8 2 2 2 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein STAT_alpha PF01017.20 GAM25653.1 - 0.87 9.5 7.0 15 5.5 6.4 2.2 1 1 0 1 1 1 0 STAT protein, all-alpha domain APG6_N PF17675.1 GAM25653.1 - 1.4 9.4 12.7 0.33 11.5 5.5 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 GAM25653.1 - 2.2 8.1 24.0 0.16 11.8 13.3 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Kelch_4 PF13418.6 GAM25654.1 - 2.9e-08 33.6 1.3 0.00082 19.3 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM25654.1 - 2.3e-06 27.7 12.0 0.0051 17.0 0.1 5.8 5 1 1 6 6 6 2 Kelch motif Kelch_1 PF01344.25 GAM25654.1 - 0.00015 21.2 0.1 0.00015 21.2 0.1 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.6 GAM25654.1 - 0.0025 18.1 0.3 1.2 9.5 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM25654.1 - 0.24 11.4 10.4 2.3 8.3 0.1 4.6 4 1 1 5 5 5 0 Kelch motif SAM_KSR1 PF13543.6 GAM25654.1 - 0.31 11.2 1.0 0.45 10.6 0.1 1.7 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 ATG_C PF09333.11 GAM25655.1 - 4.8e-16 58.9 0.0 1.5e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 GAM25655.1 - 3.8e-10 39.9 0.2 1.5e-09 38.0 0.2 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 GAM25655.1 - 1.9e-05 24.5 0.4 0.00011 22.1 0.1 2.4 2 1 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal DUF19 PF01579.18 GAM25656.1 - 0.0023 17.7 0.5 0.0054 16.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF19) FAM150 PF15129.6 GAM25656.1 - 0.015 15.5 2.0 0.047 13.8 0.1 2.3 2 0 0 2 2 2 0 FAM150 family MOR2-PAG1_N PF14222.6 GAM25656.1 - 0.029 13.3 8.2 0.074 12.0 8.2 1.7 1 1 0 1 1 1 0 Cell morphogenesis N-terminal COQ7 PF03232.13 GAM25656.1 - 0.053 13.3 0.0 0.91 9.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Fe_hyd_SSU PF02256.17 GAM25656.1 - 0.077 13.1 0.5 0.67 10.1 0.1 2.3 2 0 0 2 2 2 0 Iron hydrogenase small subunit CC2-LZ PF16516.5 GAM25656.1 - 0.31 11.4 3.2 0.65 10.4 0.7 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF948 PF06103.11 GAM25656.1 - 0.44 10.8 4.2 3.6 7.9 0.3 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 GAM25656.1 - 0.54 10.7 11.3 5.1 7.5 6.3 3.1 1 1 2 3 3 3 0 Syntaxin-like protein Fib_alpha PF08702.10 GAM25656.1 - 0.61 10.3 13.5 0.47 10.6 3.9 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family AI-2E_transport PF01594.16 GAM25656.1 - 1.4 8.0 3.7 13 4.8 1.4 2.3 2 1 0 2 2 2 0 AI-2E family transporter DUF5082 PF16888.5 GAM25656.1 - 8.1 6.7 13.0 3.5 7.9 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) PAC1 PF16094.5 GAM25657.1 - 2.6e-15 56.4 1.0 4.8e-15 55.5 1.0 1.5 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 Pep_deformylase PF01327.21 GAM25657.1 - 0.091 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Polypeptide deformylase YEATS PF03366.16 GAM25658.1 - 2.4e-13 49.8 0.9 3.1e-07 30.3 0.1 3.2 1 1 1 2 2 2 2 YEATS family YchF-GTPase_C PF06071.13 GAM25658.1 - 0.053 13.7 0.1 0.19 11.9 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF933) TFIIA PF03153.13 GAM25658.1 - 0.87 9.5 33.9 2.3 8.2 6.6 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF936 PF06075.12 GAM25659.1 - 2 7.2 39.0 2.5 6.9 39.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) ADIP PF11559.8 GAM25660.1 - 0.0046 17.0 1.7 0.0046 17.0 1.7 2.1 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Focal_AT PF03623.13 GAM25660.1 - 0.017 15.1 1.5 0.017 15.1 1.5 1.6 2 0 0 2 2 2 0 Focal adhesion targeting region BRCT_2 PF16589.5 GAM25662.1 - 1.1e-08 35.4 0.0 7.5e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 GAM25662.1 - 2.5e-07 30.5 0.0 4.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 GAM25662.1 - 1e-05 25.8 0.1 0.072 13.5 0.0 2.2 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 GAM25662.1 - 0.025 14.9 0.1 3.1 8.1 0.1 2.3 2 1 0 2 2 2 0 DNA ligase 3 BRCT domain SWIRM-assoc_2 PF16496.5 GAM25662.1 - 0.12 11.2 0.2 0.23 10.3 0.1 1.4 1 1 1 2 2 2 0 SWIRM-associated domain at the N-terminal COMM_domain PF07258.14 GAM25663.1 - 2.4e-19 69.2 1.3 1.6e-18 66.5 0.3 2.3 2 0 0 2 2 2 1 COMM domain PH_18 PF18469.1 GAM25663.1 - 0.051 13.5 3.1 0.1 12.5 0.3 2.2 1 1 1 2 2 2 0 Pleckstrin homology domain DUF5004 PF16395.5 GAM25663.1 - 0.069 13.2 0.2 0.069 13.2 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5004) BTB PF00651.31 GAM25664.1 - 4e-24 85.0 0.0 8.5e-23 80.7 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain DUF3361 PF11841.8 GAM25664.1 - 0.0015 18.5 0.5 0.016 15.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) HEAT PF02985.22 GAM25664.1 - 0.0049 17.0 0.0 3.7 8.0 0.0 3.5 3 1 1 4 4 4 1 HEAT repeat V-ATPase_H_N PF03224.14 GAM25664.1 - 0.011 15.1 0.8 0.045 13.1 0.8 1.9 1 1 0 1 1 1 0 V-ATPase subunit H BACK PF07707.15 GAM25664.1 - 0.028 14.5 0.1 0.28 11.3 0.0 2.6 3 0 0 3 3 3 0 BTB And C-terminal Kelch Arm PF00514.23 GAM25664.1 - 0.028 14.4 4.5 0.56 10.3 0.5 4.1 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat PAP1 PF08601.10 GAM25664.1 - 9.1 5.9 12.1 0.2 11.3 5.6 1.4 2 0 0 2 2 2 0 Transcription factor PAP1 Methyltransf_28 PF02636.17 GAM25665.1 - 1.2e-37 130.0 0.0 2.3e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_33 PF10017.9 GAM25665.1 - 4.3e-05 22.8 0.0 7.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent PRMT5 PF05185.16 GAM25665.1 - 0.031 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.9 GAM25665.1 - 0.044 13.5 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 GAM25665.1 - 0.046 14.5 0.0 0.12 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain HJURP_C PF12347.8 GAM25666.1 - 0.021 14.8 2.7 0.021 14.8 2.7 2.5 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat TPR_2 PF07719.17 GAM25667.1 - 1.5e-27 93.4 1.6 3.8e-05 23.5 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAM25667.1 - 5e-27 92.6 3.1 1.1e-06 28.1 0.0 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAM25667.1 - 3.8e-22 78.6 5.1 6.9e-07 29.7 0.0 5.2 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAM25667.1 - 2e-19 68.1 3.0 0.008 16.3 0.1 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAM25667.1 - 2.2e-19 69.8 0.1 6.2e-06 26.8 0.1 4.3 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM25667.1 - 3.2e-19 68.0 0.7 0.021 15.6 0.0 7.6 2 2 6 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAM25667.1 - 1.8e-18 66.6 2.8 1.6e-06 28.3 0.1 5.9 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAM25667.1 - 1.5e-17 62.2 4.0 0.00046 20.0 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM25667.1 - 3.3e-16 59.3 2.4 2.7e-06 27.5 0.0 3.8 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAM25667.1 - 8.1e-14 50.9 1.6 0.1 13.1 0.0 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM25667.1 - 3.2e-10 39.9 0.7 0.0057 16.1 0.0 4.4 2 2 1 4 4 4 2 MalT-like TPR region TPR_11 PF13414.6 GAM25667.1 - 5.4e-10 38.8 5.8 0.033 13.9 0.0 7.0 3 3 4 7 7 7 3 TPR repeat TPR_6 PF13174.6 GAM25667.1 - 2.6e-09 37.1 3.6 0.066 13.9 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM25667.1 - 5.5e-08 32.4 4.5 0.8 9.7 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM25667.1 - 5e-07 29.8 0.3 0.042 14.0 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM25667.1 - 1.2e-06 28.4 0.5 0.21 11.7 0.0 4.1 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 GAM25667.1 - 3.1e-06 26.6 0.3 0.00035 19.9 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 GAM25667.1 - 8.8e-05 23.0 1.9 0.03 14.7 0.2 3.6 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_21 PF09976.9 GAM25667.1 - 0.00017 21.4 1.8 7.7 6.2 0.0 4.2 2 1 1 4 4 4 1 Tetratricopeptide repeat-like domain SHNi-TPR PF10516.9 GAM25667.1 - 0.00043 19.7 0.1 0.028 13.9 0.0 3.5 4 0 0 4 4 3 1 SHNi-TPR PknG_TPR PF16918.5 GAM25667.1 - 0.001 17.9 0.0 0.0025 16.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat PPR PF01535.20 GAM25667.1 - 0.037 14.3 0.5 45 4.6 0.0 4.4 5 0 0 5 5 5 0 PPR repeat HrpB1_HrpK PF09613.10 GAM25667.1 - 0.039 13.6 0.6 1.5 8.5 0.2 2.9 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Cwf_Cwc_15 PF04889.12 GAM25668.1 - 0.42 10.3 20.4 0.69 9.6 20.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAF-1_p150 PF11600.8 GAM25668.1 - 1.5 8.5 21.5 2 8.1 18.4 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CENP-B_dimeris PF09026.10 GAM25668.1 - 4.3 7.8 14.5 1.1 9.7 4.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pkinase_Tyr PF07714.17 GAM25670.1 - 8e-98 326.8 0.0 3.7e-61 206.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAM25670.1 - 1.5e-81 273.6 0.0 3.3e-47 161.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 GAM25670.1 - 0.0002 20.8 0.0 0.074 12.3 0.0 2.9 3 0 0 3 3 3 2 Kinase-like FTA2 PF13095.6 GAM25670.1 - 0.052 13.2 0.1 0.52 9.9 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RRM_3 PF08777.11 GAM25671.1 - 1.1e-06 28.6 0.3 1.1e-06 28.6 0.3 2.2 1 1 1 2 2 2 1 RNA binding motif DUF1168 PF06658.12 GAM25671.1 - 0.016 15.0 12.2 0.026 14.4 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Spem1 PF15670.5 GAM25671.1 - 0.11 12.1 2.6 0.15 11.6 2.6 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Presenilin PF01080.17 GAM25671.1 - 4 6.1 6.9 4.6 5.9 6.9 1.1 1 0 0 1 1 1 0 Presenilin La PF05383.17 GAM25672.1 - 4.9e-18 64.9 0.5 1.1e-17 63.9 0.5 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 GAM25672.1 - 7.6e-13 48.1 0.0 4.5e-12 45.6 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM25672.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Dfp1_Him1_M PF08630.10 GAM25672.1 - 0.1 12.8 0.6 0.17 12.1 0.6 1.3 1 0 0 1 1 1 0 Dfp1/Him1, central region PNP_phzG_C PF10590.9 GAM25672.1 - 0.2 11.7 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Mur_ligase_M PF08245.12 GAM25673.1 - 3.3e-07 30.5 0.3 3.5e-05 23.9 0.3 3.0 1 1 0 1 1 1 1 Mur ligase middle domain SNF2_N PF00176.23 GAM25674.1 - 1.4e-66 224.6 2.2 1.4e-66 224.6 2.2 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain DBINO PF13892.6 GAM25674.1 - 1.1e-45 155.3 18.2 1.1e-45 155.3 18.2 6.7 5 1 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 GAM25674.1 - 4.7e-19 68.8 0.1 3.9e-18 65.8 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM25674.1 - 0.00018 21.3 0.0 0.00018 21.3 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Spectrin PF00435.21 GAM25675.1 - 0.0062 17.0 0.2 0.011 16.3 0.2 1.5 1 1 0 1 1 1 1 Spectrin repeat Snapin_Pallidin PF14712.6 GAM25675.1 - 0.03 14.7 1.7 0.18 12.3 0.9 2.1 1 1 1 2 2 2 0 Snapin/Pallidin UPF0114 PF03350.16 GAM25675.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 Flagellin_C PF00700.21 GAM25676.1 - 0.13 12.6 3.4 0.46 10.9 2.4 2.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region SLT_2 PF13406.6 GAM25676.1 - 0.18 11.0 2.4 0.56 9.4 0.4 2.1 2 1 0 2 2 2 0 Transglycosylase SLT domain LNP1 PF15419.6 GAM25677.1 - 2.8 8.1 18.4 0.3 11.3 10.9 2.0 1 1 1 2 2 2 0 Leukemia NUP98 fusion partner 1 SNF2_N PF00176.23 GAM25678.1 - 7.5e-58 195.9 4.2 1.3e-57 195.1 4.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM25678.1 - 2.6e-19 69.6 0.1 1.5e-18 67.2 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAM25678.1 - 0.0002 20.7 0.2 0.0002 20.7 0.2 3.8 4 1 0 4 4 4 2 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 GAM25678.1 - 0.00024 20.9 0.0 0.00059 19.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2393 PF09624.10 GAM25679.1 - 0.072 13.1 0.3 5.8 6.9 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2393) C2 PF00168.30 GAM25680.1 - 3.3e-15 56.2 0.1 5.9e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 C2 domain KH_6 PF15985.5 GAM25681.1 - 1.8e-11 44.2 0.0 3.6e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 GAM25681.1 - 1.7e-10 40.5 0.0 2.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region DUF4484 PF14831.6 GAM25681.1 - 0.074 13.1 0.3 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Pyr_redox_2 PF07992.14 GAM25682.1 - 1.8e-67 227.7 11.9 1.8e-67 227.7 11.9 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAM25682.1 - 1.6e-38 131.3 0.0 5.6e-38 129.6 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAM25682.1 - 8.2e-22 77.6 15.3 3.4e-19 69.2 1.8 4.0 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM25682.1 - 1.9e-09 37.2 13.8 4.2e-07 29.5 2.7 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM25682.1 - 2.5e-09 37.0 7.2 3.4e-09 36.6 0.7 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM25682.1 - 2.4e-06 26.5 12.1 3.1e-05 22.9 0.4 3.5 3 1 1 4 4 4 2 HI0933-like protein GIDA PF01134.22 GAM25682.1 - 4.8e-06 25.9 0.9 4.8e-06 25.9 0.9 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAM25682.1 - 6.5e-06 25.5 1.8 6.5e-06 25.5 1.8 3.9 2 1 2 4 4 4 1 FAD binding domain NAD_binding_8 PF13450.6 GAM25682.1 - 4.4e-05 23.6 6.7 0.00014 22.0 1.4 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAM25682.1 - 0.00012 21.4 5.2 0.0017 17.6 0.2 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 GAM25682.1 - 0.00013 21.4 2.9 0.0087 15.4 0.1 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 GAM25682.1 - 0.00099 18.5 11.4 0.06 12.6 0.5 3.4 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAM25682.1 - 0.0012 18.1 0.5 0.0012 18.1 0.5 3.0 2 1 1 3 3 3 1 Thi4 family Lycopene_cycl PF05834.12 GAM25682.1 - 0.0029 16.7 3.3 0.54 9.2 0.0 2.9 2 1 0 3 3 3 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAM25682.1 - 0.012 14.9 2.7 0.012 14.9 2.7 2.9 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 GAM25682.1 - 0.012 15.5 0.5 0.012 15.5 0.5 2.4 4 0 0 4 4 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 GAM25682.1 - 0.11 13.0 0.1 10 6.7 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 GAM25682.1 - 0.25 11.8 1.3 9.3 6.8 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Mqo PF06039.15 GAM25682.1 - 0.28 9.7 3.0 0.35 9.4 0.6 2.1 1 1 1 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 GAM25682.1 - 2.6 7.6 22.4 0.2 11.2 0.4 4.1 3 1 1 4 4 4 0 FAD dependent oxidoreductase Endotoxin_N PF03945.14 GAM25683.1 - 4.7e-25 88.6 8.1 1.9e-15 57.2 0.5 2.4 1 1 1 2 2 2 2 delta endotoxin, N-terminal domain Orthopox_F6 PF06601.12 GAM25683.1 - 0.22 11.7 3.6 43 4.4 0.0 4.0 4 0 0 4 4 4 0 Orthopoxvirus F6 protein TBCC_N PF16752.5 GAM25683.1 - 0.41 11.1 2.7 2.7 8.5 0.7 2.2 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain ABC2_membrane PF01061.24 GAM25684.1 - 3.4e-37 127.9 26.7 6e-37 127.1 26.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 GAM25684.1 - 1.8e-29 103.0 0.3 3.3e-29 102.1 0.0 1.6 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 GAM25684.1 - 1.2e-08 35.2 0.0 0.00086 19.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 GAM25684.1 - 2.3e-05 23.7 19.1 2.3e-05 23.7 19.1 2.1 2 1 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 GAM25684.1 - 0.00025 21.0 0.1 0.00084 19.3 0.1 1.8 2 0 0 2 2 1 1 RsgA GTPase PDR_CDR PF06422.12 GAM25684.1 - 0.00037 20.3 0.4 0.0011 18.8 0.4 1.8 1 0 0 1 1 1 1 CDR ABC transporter SMC_N PF02463.19 GAM25684.1 - 0.00066 19.2 0.0 0.012 15.0 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM25684.1 - 0.00077 19.1 0.1 0.002 17.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 GAM25684.1 - 0.0014 18.9 0.0 0.0039 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAM25684.1 - 0.0022 18.4 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 GAM25684.1 - 0.0048 16.8 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 GAM25684.1 - 0.0069 16.9 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GAM25684.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Nnf1 PF03980.14 GAM25684.1 - 0.012 16.0 0.3 0.027 14.8 0.3 1.5 1 0 0 1 1 1 0 Nnf1 NTPase_1 PF03266.15 GAM25684.1 - 0.016 15.1 0.1 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 GAM25684.1 - 0.028 13.5 0.1 0.049 12.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 GAM25684.1 - 0.028 14.9 0.4 0.065 13.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_35 PF14516.6 GAM25684.1 - 0.033 13.0 0.1 0.054 12.3 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 GAM25684.1 - 0.035 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAM25684.1 - 0.04 13.7 0.1 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAM25684.1 - 0.044 14.0 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 GAM25684.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase TsaE PF02367.17 GAM25684.1 - 0.069 13.2 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 GAM25684.1 - 0.075 13.4 0.1 0.86 10.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 GAM25684.1 - 0.095 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 GAM25684.1 - 0.12 12.8 0.1 0.29 11.6 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 GAM25684.1 - 0.12 12.0 0.6 0.47 10.1 0.0 2.3 3 1 0 3 3 2 0 Thymidylate kinase NACHT PF05729.12 GAM25684.1 - 0.16 11.9 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Nudix_hydro PF18290.1 GAM25686.1 - 1.4e-28 98.7 0.0 4.5e-28 97.1 0.0 1.9 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 GAM25686.1 - 6.9e-18 64.9 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Ax_dynein_light PF10211.9 GAM25687.1 - 0.015 15.3 0.1 0.048 13.6 0.1 1.8 1 0 0 1 1 1 0 Axonemal dynein light chain K_channel_TID PF07941.11 GAM25687.1 - 0.058 13.9 1.2 0.35 11.4 1.2 2.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF3287 PF11690.8 GAM25687.1 - 0.058 13.1 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) bZIP_2 PF07716.15 GAM25687.1 - 0.081 13.0 2.3 0.18 11.9 2.3 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Angiomotin_C PF12240.8 GAM25687.1 - 0.11 12.1 5.1 3.7 7.0 0.4 2.6 2 0 0 2 2 2 0 Angiomotin C terminal Pox_A_type_inc PF04508.12 GAM25687.1 - 0.14 12.0 1.3 0.32 10.9 1.3 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TMF_DNA_bd PF12329.8 GAM25687.1 - 0.98 9.5 4.6 0.22 11.5 0.7 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Uds1 PF15456.6 GAM25687.1 - 2.3 8.4 6.0 0.64 10.2 0.7 2.4 2 0 0 2 2 2 0 Up-regulated During Septation DUF4200 PF13863.6 GAM25687.1 - 2.6 8.5 8.3 0.069 13.5 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4094 PF13334.6 GAM25687.1 - 5.2 7.6 7.4 0.28 11.6 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) TFIIB PF00382.19 GAM25688.1 - 3.8e-25 87.7 0.0 2e-13 50.2 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 GAM25688.1 - 2e-09 37.7 4.7 2e-09 37.7 4.7 3.4 2 1 0 2 2 2 1 Brf1-like TBP-binding domain zf-RRN7 PF11781.8 GAM25688.1 - 8.5e-05 22.2 0.7 0.00018 21.1 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 GAM25688.1 - 0.00014 21.3 1.5 0.00037 19.9 1.5 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIF_alpha PF05793.12 GAM25688.1 - 0.0019 16.9 25.7 0.0037 15.9 25.7 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) A2L_zn_ribbon PF08792.10 GAM25688.1 - 0.0094 15.6 2.4 0.02 14.6 2.4 1.5 1 0 0 1 1 1 1 A2L zinc ribbon domain Cyclin_N PF00134.23 GAM25688.1 - 0.087 12.6 0.1 0.94 9.2 0.0 2.4 2 0 0 2 2 2 0 Cyclin, N-terminal domain Urease_gamma PF00547.18 GAM25688.1 - 0.14 12.5 0.2 2.4 8.5 0.1 2.6 3 0 0 3 3 3 0 Urease, gamma subunit ANAPC4_WD40 PF12894.7 GAM25689.1 - 0.0044 17.3 0.1 0.11 12.8 0.0 3.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain E1-E2_ATPase PF00122.20 GAM25690.1 - 9.6e-42 142.5 3.5 9.6e-42 142.5 3.5 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAM25690.1 - 7.7e-37 126.8 8.1 7.7e-37 126.8 8.1 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAM25690.1 - 2.4e-23 83.5 0.2 3.4e-16 60.1 0.1 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM25690.1 - 4.1e-18 65.3 0.0 7.7e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM25690.1 - 0.00074 19.3 0.1 0.0015 18.3 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAM25690.1 - 0.0036 17.7 0.0 0.099 13.0 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM25691.1 - 2.2e-09 36.8 0.0 3.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ras PF00071.22 GAM25692.1 - 1.1e-50 171.4 0.0 1.3e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM25692.1 - 1e-22 80.6 0.0 1.5e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM25692.1 - 7.8e-07 28.7 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_4 PF12799.7 GAM25693.1 - 2e-13 50.3 31.2 6e-06 26.5 5.4 4.5 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM25693.1 - 1e-12 47.6 24.5 9.2e-08 31.7 6.3 4.5 3 1 2 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 GAM25693.1 - 4.6e-07 29.5 11.9 0.0029 17.1 2.9 2.8 1 1 1 2 2 2 2 Leucine-rich repeat BBS2_C PF14782.6 GAM25693.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal LRR_6 PF13516.6 GAM25693.1 - 4.3 7.6 19.0 3.1 8.1 2.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat 3Beta_HSD PF01073.19 GAM25694.1 - 2.3e-31 108.8 0.0 3e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM25694.1 - 1e-28 100.4 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAM25694.1 - 5.7e-15 55.2 0.2 8.3e-10 38.3 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GAM25694.1 - 4e-14 52.9 0.0 5.6e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAM25694.1 - 1.6e-12 47.5 0.0 1.9e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAM25694.1 - 7.5e-11 41.7 0.5 4.1e-09 36.0 0.5 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAM25694.1 - 8.3e-11 41.5 0.0 1.2e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 GAM25694.1 - 1.7e-05 24.5 0.1 2.8e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 GAM25694.1 - 0.0056 16.2 0.2 0.011 15.2 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 GAM25694.1 - 0.009 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 GAM25694.1 - 0.012 15.6 0.4 0.16 11.8 0.4 2.3 1 1 0 1 1 1 0 KR domain F420_oxidored PF03807.17 GAM25694.1 - 0.084 13.5 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 GAM25694.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3246 PF11596.8 GAM25697.1 - 0.01 15.3 9.8 0.01 15.3 9.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3246) TFIIF_alpha PF05793.12 GAM25697.1 - 0.013 14.1 12.5 0.019 13.5 12.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AJAP1_PANP_C PF15298.6 GAM25697.1 - 0.21 11.8 9.4 0.033 14.4 5.2 1.7 2 0 0 2 2 2 0 AJAP1/PANP C-terminus DUF2457 PF10446.9 GAM25697.1 - 0.25 10.4 21.4 0.38 9.9 21.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 GAM25697.1 - 6.5 4.7 17.6 8.2 4.4 17.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4805 PF16063.5 GAM25697.1 - 7.6 5.8 11.5 0.49 9.7 5.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4805) SDA1 PF05285.12 GAM25697.1 - 8 5.8 14.5 12 5.2 14.5 1.2 1 0 0 1 1 1 0 SDA1 HAD_SAK_1 PF10307.9 GAM25698.1 - 1.8e-45 155.3 0.0 2.1e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins HAD PF12710.7 GAM25698.1 - 0.052 13.9 0.0 5.3 7.4 0.0 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Lactococcin PF04369.13 GAM25698.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Lactococcin-like family Myticin-prepro PF10690.9 GAM25699.1 - 0.001 19.3 0.1 0.0015 18.7 0.1 1.2 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel TFIIIC_sub6 PF10419.9 GAM25700.1 - 4.2e-14 52.2 3.6 7.4e-14 51.4 2.7 2.0 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain Macoilin PF09726.9 GAM25700.1 - 3.3 6.1 23.7 0.19 10.3 14.1 2.0 2 0 0 2 2 2 0 Macoilin family AMPK1_CBM PF16561.5 GAM25701.1 - 3.5e-36 123.3 0.7 5.5e-36 122.6 0.2 1.6 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 GAM25701.1 - 1.2e-21 76.8 6.2 1.2e-21 76.8 6.2 2.3 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 GAM25701.1 - 0.0032 17.8 0.1 0.0089 16.4 0.0 1.7 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) UBM PF14377.6 GAM25701.1 - 0.29 10.6 0.1 0.29 10.6 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin binding region SMYLE_N PF18615.1 GAM25701.1 - 1.9 8.0 5.2 2.8 7.4 5.2 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain GFA PF04828.14 GAM25702.1 - 0.00025 21.3 2.0 0.00025 21.3 2.0 1.9 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DPBB_1 PF03330.18 GAM25704.1 - 6.8e-07 29.5 2.7 4.4e-06 26.9 0.2 2.9 2 1 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GAM25704.1 - 0.0041 17.1 0.0 0.0096 15.9 0.0 1.6 1 0 0 1 1 1 1 Pollen allergen Cerato-platanin PF07249.12 GAM25704.1 - 0.0089 16.1 0.4 0.018 15.1 0.3 1.6 1 1 0 1 1 1 1 Cerato-platanin DPBB_1 PF03330.18 GAM25705.1 - 5.2e-07 29.9 0.7 6.2e-06 26.4 0.7 2.3 1 1 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 GAM25705.1 - 0.0021 18.2 0.3 0.0041 17.2 0.3 1.5 1 0 0 1 1 1 1 Cerato-platanin FGF-BP1 PF06473.12 GAM25705.1 - 0.0056 16.5 0.2 0.0082 16.0 0.2 1.1 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) Mfp-3 PF04202.13 GAM25705.1 - 0.068 13.6 1.4 0.16 12.4 1.4 1.6 1 0 0 1 1 1 0 Foot protein 3 FAP PF07174.11 GAM25705.1 - 0.48 9.8 17.2 0.79 9.1 17.2 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PRIMA1 PF16101.5 GAM25706.1 - 0.055 13.5 5.0 0.13 12.3 5.0 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-RING_2 PF13639.6 GAM25707.1 - 7.3e-13 48.6 8.2 1.1e-12 48.0 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM25707.1 - 4.4e-10 39.2 8.4 7.1e-10 38.6 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM25707.1 - 3e-08 33.4 8.2 5.1e-08 32.7 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM25707.1 - 6.1e-08 32.8 10.5 2.5e-07 30.9 10.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAM25707.1 - 6.1e-07 29.1 2.5 1.2e-06 28.1 2.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 GAM25707.1 - 8.4e-06 25.6 4.4 1.2e-05 25.1 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM25707.1 - 1.2e-05 25.2 4.2 2.4e-05 24.3 4.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAM25707.1 - 2.2e-05 24.3 7.1 3.6e-05 23.6 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAM25707.1 - 0.00061 19.8 5.1 0.0017 18.4 5.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAM25707.1 - 0.00069 19.4 5.2 0.0012 18.6 5.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 GAM25707.1 - 0.00076 19.3 5.5 0.0014 18.4 5.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 T6SS_VipA PF05591.12 GAM25707.1 - 0.0034 17.2 1.5 0.0049 16.7 1.5 1.2 1 0 0 1 1 1 1 Type VI secretion system, VipA, VC_A0107 or Hcp2 FANCL_C PF11793.8 GAM25707.1 - 0.0043 17.2 8.4 0.017 15.3 8.4 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAM25707.1 - 0.015 14.9 4.3 0.026 14.1 4.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 GAM25707.1 - 0.022 14.9 7.1 0.042 14.0 7.1 1.4 1 0 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.11 GAM25707.1 - 0.03 14.3 1.2 0.062 13.3 1.2 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.11 GAM25707.1 - 0.043 14.1 4.0 0.043 14.1 4.0 1.6 2 0 0 2 2 2 0 RING-like domain FGGY_N PF00370.21 GAM25707.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain zf-P11 PF03854.14 GAM25707.1 - 0.23 11.2 7.1 0.85 9.3 7.1 2.0 1 1 0 1 1 1 0 P-11 zinc finger PHD PF00628.29 GAM25707.1 - 0.51 10.3 6.9 0.91 9.5 6.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 GAM25707.1 - 2.2 8.5 5.6 4.6 7.5 5.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 GAM25707.1 - 2.3 8.2 5.9 4.2 7.4 2.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF1765 PF08578.10 GAM25708.1 - 2.7e-23 82.8 5.6 3.3e-23 82.5 3.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Sep15_SelM PF08806.11 GAM25709.1 - 1.3e-08 34.9 0.0 1.4e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Sep15/SelM redox domain GalBD_like PF17974.1 GAM25709.1 - 0.041 14.0 0.0 0.041 14.0 0.0 1.0 1 0 0 1 1 1 0 Galactose-binding domain-like ACC_central PF08326.12 GAM25711.1 - 7.3e-167 556.8 0.7 9.8e-167 556.3 0.7 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 GAM25711.1 - 6.3e-160 533.0 0.0 9e-160 532.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 GAM25711.1 - 1.3e-51 175.2 0.0 2.5e-51 174.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAM25711.1 - 1e-28 100.1 0.1 2.5e-28 98.8 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAM25711.1 - 3.4e-19 68.9 0.0 8.8e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAM25711.1 - 1.1e-10 41.2 0.0 2.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 GAM25711.1 - 3.9e-06 27.0 0.1 1.3e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 GAM25711.1 - 4.2e-06 26.4 0.0 1.2e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAM25711.1 - 7.9e-06 25.5 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 GAM25711.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Sec1 PF00995.23 GAM25712.1 - 2.7e-125 419.8 7.9 3.2e-125 419.6 7.9 1.0 1 0 0 1 1 1 1 Sec1 family V-ATPase_H_C PF11698.8 GAM25712.1 - 0.056 13.6 0.2 0.25 11.4 0.2 2.2 1 1 0 1 1 1 0 V-ATPase subunit H Pkinase_Tyr PF07714.17 GAM25713.1 - 3.1e-69 233.2 0.0 5.4e-69 232.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM25713.1 - 3.6e-63 213.4 0.0 8.8e-63 212.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 GAM25713.1 - 0.0069 15.7 0.4 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like UPF0047 PF01894.17 GAM25713.1 - 0.059 13.5 0.4 0.18 12.0 0.4 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 Kdo PF06293.14 GAM25713.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM25713.1 - 0.11 11.4 16.6 0.25 10.3 8.4 3.7 2 1 0 2 2 2 0 Haspin like kinase domain TFIIA PF03153.13 GAM25713.1 - 0.14 12.1 41.6 0.31 11.0 20.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit S36_mt PF10937.8 GAM25714.1 - 0.074 14.6 0.5 0.074 14.6 0.5 2.0 2 0 0 2 2 2 0 Ribosomal protein S36, mitochondrial Phage_Mu_Gam PF07352.12 GAM25714.1 - 0.81 9.6 6.1 0.095 12.6 0.8 2.0 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein CDC27 PF09507.10 GAM25715.1 - 5.9e-11 42.4 47.8 5.9e-11 42.4 47.8 3.3 1 1 2 3 3 3 2 DNA polymerase subunit Cdc27 Sugar_tr PF00083.24 GAM25716.1 - 5.9e-110 368.2 33.2 6.8e-110 368.0 33.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAM25716.1 - 8.1e-49 166.4 39.6 6.1e-33 114.2 8.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAM25716.1 - 2.1e-12 46.3 12.8 1.3e-09 37.0 4.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 GAM25716.1 - 1.2e-08 34.7 3.4 1.2e-08 34.7 3.4 2.4 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 GAM25716.1 - 1.3e-07 30.5 33.4 1.2e-05 24.1 10.0 3.8 2 2 2 4 4 4 3 MFS/sugar transport protein Clat_adaptor_s PF01217.20 GAM25717.1 - 1.1e-36 125.9 4.6 1.3e-36 125.7 4.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SNAP PF14938.6 GAM25718.1 - 1.9e-11 43.9 10.6 5.1e-11 42.5 4.9 2.6 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 GAM25718.1 - 2.7e-07 30.8 2.7 0.00035 20.8 0.3 4.3 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM25718.1 - 1.3e-06 28.1 5.3 0.00031 20.6 0.1 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM25718.1 - 2.4e-05 24.2 5.0 0.0015 18.6 0.3 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM25718.1 - 2.9e-05 23.8 0.2 0.0017 18.2 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM25718.1 - 3.9e-05 23.3 7.6 0.0011 18.7 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.9 GAM25718.1 - 0.0023 17.7 8.5 0.016 15.0 2.0 2.8 2 1 2 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 GAM25718.1 - 0.013 15.7 5.0 0.41 10.9 0.1 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GAM25718.1 - 0.017 15.0 0.5 0.13 12.2 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM25718.1 - 0.023 14.1 3.4 0.035 13.5 3.4 1.2 1 0 0 1 1 1 0 MalT-like TPR region PhoQ_Sensor PF08918.10 GAM25718.1 - 0.074 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 PhoQ Sensor TPR_14 PF13428.6 GAM25718.1 - 0.12 13.3 0.3 2.3 9.3 0.1 3.3 4 1 1 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM25718.1 - 0.37 11.5 1.8 14 6.6 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM25718.1 - 0.7 9.6 10.2 3.8 7.3 0.2 4.5 5 0 0 5 5 5 0 TPR repeat UCH PF00443.29 GAM25719.1 - 6e-42 143.9 1.7 6e-42 143.9 1.7 2.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM25719.1 - 8.6e-23 81.4 2.6 8.6e-23 81.4 2.6 3.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1765 PF08578.10 GAM25719.1 - 0.49 10.9 3.6 16 6.0 0.2 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) Podoplanin PF05808.11 GAM25719.1 - 6 7.0 12.9 16 5.6 12.9 1.7 1 0 0 1 1 1 0 Podoplanin BUD22 PF09073.10 GAM25720.1 - 0.0011 18.5 15.5 0.0011 18.5 15.5 1.4 1 1 0 1 1 1 1 BUD22 TP1 PF02079.16 GAM25720.1 - 0.027 14.4 2.8 0.056 13.4 2.8 1.5 1 0 0 1 1 1 0 Nuclear transition protein 1 CENP-B_dimeris PF09026.10 GAM25720.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain SOG2 PF10428.9 GAM25720.1 - 1.1 8.4 20.7 1.7 7.7 20.7 1.3 1 1 0 1 1 1 0 RAM signalling pathway protein PBP1_TM PF14812.6 GAM25720.1 - 2.3 8.7 17.6 1.6 9.1 15.3 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mucin PF01456.17 GAM25720.1 - 3.8 7.5 22.7 0.72 9.8 18.8 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2201_N PF13203.6 GAM25720.1 - 4.1 6.9 10.2 1.4 8.4 6.4 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain Pkinase PF00069.25 GAM25721.1 - 2.7e-75 253.1 0.0 3.1e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25721.1 - 2.2e-38 132.0 0.0 2.7e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM25721.1 - 3.7e-06 26.4 0.1 6.2e-06 25.7 0.1 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM25721.1 - 0.0023 17.3 0.1 0.077 12.3 0.0 2.4 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 GAM25721.1 - 0.054 13.4 0.1 0.34 10.8 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4730 PF15873.5 GAM25722.1 - 2.8e-05 24.3 0.5 3.3e-05 24.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4730) Deltameth_res PF16020.5 GAM25722.1 - 8 6.4 6.8 7.4 6.5 0.4 2.2 1 1 1 2 2 2 0 Deltamethrin resistance SOG2 PF10428.9 GAM25723.1 - 2.9 7.0 33.8 4.2 6.4 33.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 GAM25723.1 - 3.5 7.1 9.7 4.4 6.8 9.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.9 GAM25723.1 - 3.6 6.0 11.7 5.3 5.5 11.7 1.3 1 0 0 1 1 1 0 Macoilin family Laminin_G_3 PF13385.6 GAM25725.1 - 3e-10 40.5 0.1 9.9e-10 38.8 0.1 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Atx10homo_assoc PF09759.9 GAM25725.1 - 7.4e-05 22.7 15.2 3.1 7.9 0.0 7.9 8 0 0 8 8 8 3 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 GAM25725.1 - 0.052 13.9 0.1 90 3.6 0.0 4.3 4 0 0 4 4 4 0 HEAT repeats TetR_C_19 PF17924.1 GAM25725.1 - 1 9.9 11.3 0.63 10.6 0.5 4.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FNIP PF05725.12 GAM25726.1 - 3.8e-97 318.2 37.1 4.6e-14 52.3 0.1 13.0 9 5 4 13 13 13 12 FNIP Repeat Glyco_hydro_65C PF03633.15 GAM25726.1 - 0.039 13.9 1.0 34 4.4 0.0 5.4 5 0 0 5 5 5 0 Glycosyl hydrolase family 65, C-terminal domain Mito_carr PF00153.27 GAM25727.1 - 5.7e-70 231.3 2.9 4.8e-24 84.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAM25727.1 - 0.0093 15.1 1.5 2.7 7.1 0.0 3.6 3 1 1 4 4 4 2 Gammaproteobacterial serine protease Glyco_hydro_63 PF03200.16 GAM25728.1 - 1.7e-08 33.7 11.3 1.7e-06 27.1 1.2 4.7 4 2 0 4 4 4 3 Glycosyl hydrolase family 63 C-terminal domain OHCU_decarbox PF09349.10 GAM25729.1 - 1.3e-37 129.7 0.0 2.3e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 OHCU decarboxylase Amidohydro_1 PF01979.20 GAM25729.1 - 3.7e-27 95.5 0.0 5.4e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM25729.1 - 1.4e-12 47.9 0.3 4.4e-09 36.3 0.0 2.9 2 1 1 3 3 3 2 Amidohydrolase family Sec23_trunk PF04811.15 GAM25729.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain WD40_alt PF14077.6 GAM25729.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Redoxin PF08534.10 GAM25730.1 - 9.9e-10 38.3 0.1 1.4e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Redoxin Qua1 PF16274.5 GAM25730.1 - 0.073 12.9 0.1 5.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Qua1 domain AhpC-TSA PF00578.21 GAM25730.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family HAD PF12710.7 GAM25731.1 - 1.6e-16 61.3 0.0 2.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAM25731.1 - 5.5e-10 39.9 0.0 2.9e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 GAM25731.1 - 1.5e-05 24.6 0.0 4.3e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase_3 PF08282.12 GAM25731.1 - 2.4e-05 24.2 0.2 0.00019 21.3 0.0 2.4 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAM25731.1 - 0.041 14.0 0.0 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Striatin PF08232.12 GAM25732.1 - 0.058 14.0 0.1 0.058 14.0 0.1 7.3 4 2 2 6 6 6 0 Striatin family Coiled PF05710.12 GAM25733.1 - 0.00043 21.1 9.2 0.00058 20.6 9.2 1.2 1 0 0 1 1 1 1 Coiled coil EGF_2 PF07974.13 GAM25734.1 - 3.9e-07 30.3 38.3 0.00023 21.5 12.6 3.5 3 0 0 3 3 3 2 EGF-like domain EGF_Tenascin PF18720.1 GAM25734.1 - 0.00039 20.4 26.5 0.003 17.6 6.1 3.1 3 0 0 3 3 3 2 Tenascin EGF domain FNIP PF05725.12 GAM25735.1 - 8.1e-78 256.4 15.7 2.2e-13 50.1 0.0 8.6 6 1 4 10 10 10 9 FNIP Repeat DUF743 PF05332.11 GAM25735.1 - 0.02 15.0 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF743) EGF_2 PF07974.13 GAM25736.1 - 0.00097 19.5 39.8 0.011 16.1 14.5 3.3 3 0 0 3 3 3 2 EGF-like domain EGF_Tenascin PF18720.1 GAM25736.1 - 0.049 13.7 24.1 0.072 13.2 7.1 3.0 2 0 0 2 2 2 0 Tenascin EGF domain UPF0542 PF15086.6 GAM25736.1 - 0.16 11.9 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 EGF_2 PF07974.13 GAM25737.1 - 4.5e-06 26.9 37.4 0.00088 19.6 8.3 3.3 3 0 0 3 3 3 2 EGF-like domain EGF_Tenascin PF18720.1 GAM25737.1 - 0.0038 17.2 26.3 0.0098 15.9 7.1 2.9 2 0 0 2 2 2 2 Tenascin EGF domain EGF_2 PF07974.13 GAM25738.1 - 1.8e-06 28.2 33.4 0.006 16.9 10.9 3.1 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 GAM25738.1 - 0.015 15.3 21.5 0.52 10.4 8.8 2.7 2 0 0 2 2 2 0 Tenascin EGF domain Nodulin-like PF06813.13 GAM25739.1 - 6.2e-23 81.6 8.6 6.2e-23 81.6 8.6 2.4 2 1 0 2 2 2 1 Nodulin-like MFS_1 PF07690.16 GAM25739.1 - 3.9e-14 52.4 30.7 3.5e-07 29.5 9.5 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily COMM_domain PF07258.14 GAM25740.1 - 2.2e-17 62.9 0.2 6.5e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 COMM domain Sulfotransfer_2 PF03567.14 GAM25741.1 - 9.9e-09 35.5 1.8 1.7e-08 34.7 0.2 2.1 2 0 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 GAM25741.1 - 5.7e-05 22.2 0.1 0.00057 18.9 0.1 2.2 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Med15 PF09606.10 GAM25741.1 - 0.0091 14.7 2.1 0.013 14.2 2.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Sulfotransfer_1 PF00685.27 GAM25741.1 - 0.039 13.4 0.4 0.14 11.7 0.4 2.1 1 1 0 1 1 1 0 Sulfotransferase domain G-alpha PF00503.20 GAM25742.1 - 3.8e-100 335.5 10.8 5.5e-100 335.0 10.8 1.2 1 0 0 1 1 1 1 G-protein alpha subunit PH PF00169.29 GAM25742.1 - 2.9e-18 66.3 0.7 8.6e-18 64.8 0.4 2.0 2 0 0 2 2 2 1 PH domain Arf PF00025.21 GAM25742.1 - 5e-13 48.9 0.7 4.4e-10 39.3 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM25742.1 - 2.2e-05 23.9 6.8 4.5e-05 22.9 0.9 2.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM25742.1 - 0.00045 20.4 1.6 0.23 11.7 0.0 3.2 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase PH_11 PF15413.6 GAM25742.1 - 0.0018 18.7 2.5 0.0063 16.9 0.4 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 GAM25742.1 - 0.0025 18.0 0.1 0.009 16.3 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain TniB PF05621.11 GAM25742.1 - 0.035 13.5 0.1 0.074 12.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial TniB protein PH_9 PF15410.6 GAM25742.1 - 0.046 14.1 0.1 0.14 12.5 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain GTP_EFTU PF00009.27 GAM25742.1 - 0.099 12.2 1.4 0.58 9.7 0.2 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Rsa3 PF14615.6 GAM25743.1 - 3.4e-09 36.1 0.3 7.2e-09 35.1 0.3 1.6 1 0 0 1 1 1 1 Ribosome-assembly protein 3 zf-RING_2 PF13639.6 GAM25744.1 - 1.1e-08 35.2 6.8 1.1e-08 35.2 6.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAM25744.1 - 6.5e-08 32.3 7.4 6.5e-08 32.3 7.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 GAM25744.1 - 1.7e-07 31.6 0.0 3.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 GAM25744.1 - 8.8e-07 28.7 7.4 8.8e-07 28.7 7.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM25744.1 - 1.5e-06 28.0 6.4 1.5e-06 28.0 6.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM25744.1 - 3.6e-06 26.7 7.8 3.6e-06 26.7 7.8 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM25744.1 - 5.7e-05 23.1 5.5 5.7e-05 23.1 5.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAM25744.1 - 7.3e-05 22.5 5.3 0.00023 20.9 5.3 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAM25744.1 - 0.00026 21.1 8.9 0.00084 19.5 8.9 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Dicty_REP PF05086.12 GAM25744.1 - 0.0018 16.4 3.9 0.0018 16.4 3.9 1.6 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein zf-rbx1 PF12678.7 GAM25744.1 - 0.01 16.1 3.1 0.01 16.1 3.1 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-Nse PF11789.8 GAM25744.1 - 0.14 12.0 4.0 0.35 10.7 4.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 GAM25744.1 - 0.27 11.0 8.9 0.12 12.1 5.1 2.5 2 0 0 2 2 2 0 RING-like zinc finger AJAP1_PANP_C PF15298.6 GAM25744.1 - 0.3 11.3 13.3 0.61 10.3 13.3 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus zf-RING_6 PF14835.6 GAM25744.1 - 0.34 10.8 2.9 0.88 9.5 2.9 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Mucin PF01456.17 GAM25744.1 - 0.39 10.7 23.3 0.76 9.8 23.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 GAM25744.1 - 0.65 10.0 18.0 1.4 8.9 18.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-ANAPC11 PF12861.7 GAM25744.1 - 1.5 8.9 7.2 0.06 13.4 1.3 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FSA_C PF10479.9 GAM25744.1 - 3.9 5.5 9.7 5.7 4.9 9.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Dmrt1 PF12374.8 GAM25744.1 - 4.3 7.8 9.5 8.6 6.9 9.5 1.5 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 SSP160 PF06933.11 GAM25744.1 - 5.5 5.1 19.9 8.6 4.4 19.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SNF2_N PF00176.23 GAM25745.1 - 8.3e-75 251.7 1.0 1.4e-74 250.9 1.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 GAM25745.1 - 0.0025 17.7 9.9 0.0025 17.7 9.9 2.3 2 0 0 2 2 2 1 PHD-finger zf-CW PF07496.15 GAM25745.1 - 0.068 13.2 4.8 0.22 11.6 4.8 1.9 1 0 0 1 1 1 0 CW-type Zinc Finger Ank_4 PF13637.6 GAM25745.1 - 0.15 12.7 0.0 32 5.2 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) CHDCT2 PF08074.11 GAM25746.1 - 0.12 12.5 0.4 0.31 11.2 0.4 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain TFIIA PF03153.13 GAM25746.1 - 5.3 6.9 38.3 6.2 6.7 23.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit T4_deiodinase PF00837.17 GAM25747.1 - 2.2e-26 92.6 0.0 2.5e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase UL16 PF17622.2 GAM25747.1 - 0.0049 16.5 0.0 0.0062 16.2 0.0 1.1 1 0 0 1 1 1 1 Viral unique long protein 16 JmjC PF02373.22 GAM25748.1 - 0.16 12.4 0.0 0.17 12.3 0.0 1.0 1 0 0 1 1 1 0 JmjC domain, hydroxylase Sulfate_transp PF00916.20 GAM25749.1 - 2.3e-104 349.2 24.6 3e-104 348.8 23.4 1.8 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 GAM25749.1 - 1e-22 79.9 0.0 2.5e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 GAM25749.1 - 0.00028 21.2 0.0 0.00055 20.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain PHA_synth_III_E PF09712.10 GAM25749.1 - 0.11 11.6 0.3 0.17 10.9 0.3 1.2 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Usp PF00582.26 GAM25750.1 - 6.2 7.3 5.9 4.4 7.8 0.5 2.5 2 0 0 2 2 2 0 Universal stress protein family BSP_II PF05432.11 GAM25751.1 - 0.0068 16.1 30.0 0.0068 16.1 30.0 2.8 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) DUF3086 PF11285.8 GAM25751.1 - 0.095 11.8 0.0 0.095 11.8 0.0 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3086) DUF936 PF06075.12 GAM25751.1 - 4.1 6.2 60.8 2.3 7.0 39.2 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF936) Utp14 PF04615.13 GAM25751.1 - 5 5.6 63.1 4.4 5.8 7.8 2.2 2 0 0 2 2 2 0 Utp14 protein NmrA PF05368.13 GAM25752.1 - 3.5e-11 43.1 0.0 2.2e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAM25752.1 - 0.0022 17.9 0.0 0.0054 16.7 0.0 1.7 2 1 0 2 2 2 1 NAD(P)H-binding Kelch_4 PF13418.6 GAM25753.1 - 4.3e-12 45.9 0.5 9.3e-06 25.6 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM25753.1 - 1.9e-11 43.8 3.5 5.8e-05 23.2 0.0 4.5 5 0 0 5 5 4 2 Kelch motif Kelch_3 PF13415.6 GAM25753.1 - 1.6e-08 34.6 0.7 0.0019 18.4 0.0 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM25753.1 - 7.2e-08 31.9 2.8 0.0016 18.0 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAM25753.1 - 0.0021 18.0 4.2 1.4 9.0 1.8 3.1 2 1 1 3 3 3 2 Kelch motif Baculo_PEP_C PF04513.12 GAM25753.1 - 0.0022 18.0 2.1 0.0096 16.0 1.6 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_5 PF13854.6 GAM25753.1 - 0.003 17.5 4.2 0.24 11.4 0.3 2.7 2 0 0 2 2 2 2 Kelch motif Syntaxin PF00804.25 GAM25753.1 - 0.0078 15.9 2.4 0.014 15.0 2.4 1.4 1 0 0 1 1 1 1 Syntaxin FliT PF05400.13 GAM25753.1 - 0.0095 16.7 1.6 0.011 16.5 0.4 1.7 2 0 0 2 2 1 1 Flagellar protein FliT RPW8 PF05659.11 GAM25753.1 - 0.069 12.8 0.6 0.18 11.5 0.6 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 4HB_MCP_1 PF12729.7 GAM25753.1 - 0.1 12.2 2.8 0.21 11.1 1.1 2.1 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction LON_substr_bdg PF02190.16 GAM25753.1 - 0.13 12.1 1.2 0.22 11.4 1.2 1.3 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Prominin PF05478.11 GAM25753.1 - 0.13 10.2 4.5 0.35 8.8 4.4 1.6 2 0 0 2 2 2 0 Prominin DUF1664 PF07889.12 GAM25753.1 - 0.25 11.4 4.2 0.5 10.4 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 GAM25753.1 - 0.38 11.1 4.2 5.5 7.3 4.2 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 GAM25753.1 - 0.4 9.9 2.7 0.81 8.9 2.7 1.5 1 0 0 1 1 1 0 TMPIT-like protein SF-assemblin PF06705.11 GAM25753.1 - 0.61 9.4 8.1 0.41 10.0 5.3 1.8 2 0 0 2 2 2 0 SF-assemblin/beta giardin Pkinase PF00069.25 GAM25754.1 - 3.1e-32 112.0 0.4 3.5e-30 105.2 0.0 2.8 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25754.1 - 6.4e-32 110.8 0.1 1.2e-29 103.4 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAM25754.1 - 8.5e-05 21.7 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM25754.1 - 0.0008 18.3 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAM25754.1 - 0.07 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 GAM25754.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Dynamin_N PF00350.23 GAM25755.1 - 1.3e-07 31.8 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 GAM25755.1 - 2.2e-05 24.4 0.0 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 GAM25755.1 - 3.2e-05 24.0 0.1 0.0003 20.8 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAM25755.1 - 0.00012 22.6 0.0 0.00026 21.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Pox_A32 PF04665.12 GAM25755.1 - 0.00073 19.1 2.1 0.0014 18.2 0.1 2.1 2 1 0 2 2 2 1 Poxvirus A32 protein Septin PF00735.18 GAM25755.1 - 0.00088 18.6 0.4 0.0018 17.6 0.1 1.6 2 0 0 2 2 2 1 Septin AAA_16 PF13191.6 GAM25755.1 - 0.0012 19.3 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 GAM25755.1 - 0.0039 16.9 1.6 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 GAM25755.1 - 0.0072 15.4 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 GAM25755.1 - 0.011 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAM25755.1 - 0.017 15.4 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 GAM25755.1 - 0.021 14.4 0.2 0.037 13.6 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 GAM25755.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 GAM25755.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 GAM25755.1 - 0.057 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 GAM25755.1 - 0.059 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 GAM25755.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 GAM25755.1 - 0.066 13.1 0.8 0.1 12.5 0.1 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.6 GAM25755.1 - 0.089 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 GAM25755.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 GAM25755.1 - 0.13 12.7 0.6 0.24 11.9 0.2 1.6 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 GAM25755.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAM25755.1 - 0.15 12.1 0.1 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HECT PF00632.25 GAM25756.1 - 2.3e-98 329.5 1.6 4.1e-98 328.7 0.1 2.3 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 GAM25756.1 - 2.6e-30 106.1 10.6 3e-20 72.9 0.6 6.0 4 2 2 6 6 6 2 Domain of Unknown Function (DUF908) DUF913 PF06025.12 GAM25756.1 - 9.9e-28 97.2 3.4 2.3e-27 95.9 2.4 6.6 4 2 1 6 6 6 2 Domain of Unknown Function (DUF913) UBM PF14377.6 GAM25756.1 - 1e-20 72.5 18.3 1.7e-10 40.0 3.0 5.0 3 1 1 4 4 4 3 Ubiquitin binding region UBA PF00627.31 GAM25756.1 - 0.023 14.6 0.0 0.072 13.0 0.0 1.9 1 0 0 1 1 1 0 UBA/TS-N domain DUF2254 PF10011.9 GAM25757.1 - 0.016 14.0 0.8 0.032 13.1 0.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Ank_2 PF12796.7 GAM25759.1 - 4.4e-38 129.7 27.3 1.1e-07 32.4 2.7 10.5 8 2 3 12 12 12 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM25759.1 - 8.1e-28 96.4 22.1 2.2e-06 28.1 0.4 11.6 7 3 3 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM25759.1 - 7.5e-20 70.7 16.2 0.0013 19.0 0.0 11.1 8 2 2 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM25759.1 - 1.5e-13 49.5 30.3 0.39 11.4 0.1 15.7 18 0 0 18 18 18 3 Ankyrin repeat Ank PF00023.30 GAM25759.1 - 8.4e-13 48.2 28.1 0.012 16.1 0.4 11.8 12 0 0 12 12 12 4 Ankyrin repeat SecA_DEAD PF07517.14 GAM25759.1 - 1.1e-06 28.2 0.0 0.00062 19.2 0.0 2.4 2 0 0 2 2 2 2 SecA DEAD-like domain SecA_PP_bind PF01043.20 GAM25759.1 - 3.3e-05 24.5 0.1 0.00037 21.1 0.0 2.6 2 0 0 2 2 2 1 SecA preprotein cross-linking domain Helicase_C PF00271.31 GAM25759.1 - 0.042 14.2 0.1 0.22 11.9 0.0 2.4 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Ank_2 PF12796.7 GAM25760.1 - 0.0035 17.9 0.0 0.017 15.7 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF5049 PF16468.5 GAM25760.1 - 0.0042 16.9 0.2 0.79 9.7 0.0 3.1 2 1 2 4 4 4 1 Domain of unknown function (DUF5049) Ank_3 PF13606.6 GAM25760.1 - 0.084 13.5 0.1 7.6 7.5 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat SASRP1 PF15160.6 GAM25761.1 - 0.097 12.3 2.5 0.19 11.4 2.5 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 SOG2 PF10428.9 GAM25761.1 - 1.1 8.4 16.5 0.14 11.3 0.3 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Bromodomain PF00439.25 GAM25762.1 - 1.1e-17 63.9 1.3 2.4e-17 62.8 1.3 1.6 1 0 0 1 1 1 1 Bromodomain Sec23_trunk PF04811.15 GAM25763.1 - 3.3e-64 216.8 0.0 5.5e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GAM25763.1 - 9.2e-30 103.2 0.2 1.8e-29 102.3 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 GAM25763.1 - 2.9e-24 84.9 0.2 5.7e-24 83.9 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GAM25763.1 - 1.7e-12 47.2 7.3 3.1e-12 46.3 7.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAM25763.1 - 4e-12 45.9 0.0 1.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 GAM25763.1 - 0.075 12.4 0.3 0.18 11.2 0.3 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain MutS_IV PF05190.18 GAM25763.1 - 0.14 12.5 0.0 0.43 11.0 0.0 1.7 2 0 0 2 2 2 0 MutS family domain IV DUF2251 PF10008.9 GAM25764.1 - 0.032 14.3 0.2 0.068 13.3 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2251) Ribosomal_S5_C PF03719.15 GAM25764.1 - 0.084 12.3 0.3 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain Dicty_REP PF05086.12 GAM25764.1 - 0.2 9.6 10.1 0.33 8.9 10.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MCM_bind PF09739.9 GAM25764.1 - 1.1 7.6 6.3 0.54 8.7 4.2 1.5 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor BSP_II PF05432.11 GAM25764.1 - 1.2 8.8 18.3 1.3 8.7 12.1 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) ATP11 PF06644.11 GAM25764.1 - 2 8.2 6.1 3.3 7.4 6.1 1.3 1 0 0 1 1 1 0 ATP11 protein SPG4 PF17325.2 GAM25764.1 - 5.4 8.2 8.9 2.8 9.1 5.7 2.2 2 1 0 2 2 2 0 Stationary phase protein 4 FNIP PF05725.12 GAM25765.1 - 4.5e-27 93.9 25.7 5.3e-09 36.1 1.6 6.4 3 2 5 8 8 8 7 FNIP Repeat DUF1769 PF08588.10 GAM25765.1 - 0.015 15.4 1.9 2.8 8.2 0.0 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1769) TIG PF01833.24 GAM25766.1 - 0.00066 19.7 6.5 0.00066 19.7 6.5 8.0 6 2 2 8 8 8 3 IPT/TIG domain Pheromone PF08015.11 GAM25767.1 - 1.3 10.1 7.3 5.5 8.1 7.3 2.1 1 0 0 1 1 1 0 Fungal mating-type pheromone TIG PF01833.24 GAM25769.1 - 1.1e-54 182.4 140.2 9.8e-14 51.2 0.4 18.1 17 1 1 18 18 18 10 IPT/TIG domain DNase_II PF03265.15 GAM25769.1 - 3e-27 95.8 1.8 3.4e-27 95.6 0.1 2.0 2 0 0 2 2 2 1 Deoxyribonuclease II SdrD_B PF17210.3 GAM25769.1 - 1.5e-12 47.7 45.9 6.6e-08 32.8 0.4 7.3 7 0 0 7 7 7 3 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM25769.1 - 2.2e-06 27.9 3.4 0.00022 21.4 0.7 6.2 5 0 0 5 5 5 2 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 GAM25769.1 - 0.016 15.4 0.9 0.49 10.5 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2012) DUF3244 PF11589.8 GAM25769.1 - 0.36 10.9 4.2 0.73 10.0 0.2 3.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) DNase_II PF03265.15 GAM25770.1 - 5.7e-26 91.6 0.0 2.2e-25 89.6 0.0 2.0 1 1 0 1 1 1 1 Deoxyribonuclease II TIG PF01833.24 GAM25770.1 - 1e-25 89.6 96.7 6.2e-11 42.2 2.1 13.2 11 2 1 12 12 12 8 IPT/TIG domain SdrD_B PF17210.3 GAM25770.1 - 6.2e-13 49.0 9.5 3.2e-07 30.5 0.2 4.2 4 0 0 4 4 4 2 SdrD B-like domain PRKCSH_1 PF13015.6 GAM25770.1 - 7.9e-11 41.9 3.3 0.17 11.6 0.1 4.7 3 1 0 4 4 4 4 Glucosidase II beta subunit-like protein CarboxypepD_reg PF13620.6 GAM25770.1 - 2.3e-05 24.6 1.6 2.3e-05 24.6 1.6 5.5 6 0 0 6 6 6 1 Carboxypeptidase regulatory-like domain fn3_3 PF14686.6 GAM25770.1 - 0.0048 16.6 3.6 0.0064 16.3 0.1 3.0 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarbopepD_reg_2 PF13715.6 GAM25770.1 - 0.037 14.0 4.6 2.3 8.3 0.3 3.1 2 0 0 2 2 2 0 CarboxypepD_reg-like domain Coiled PF05710.12 GAM25771.1 - 0.38 11.6 14.3 0.61 10.9 14.3 1.4 1 1 0 1 1 1 0 Coiled coil ELO PF01151.18 GAM25772.1 - 6.3e-60 202.8 31.8 7.5e-60 202.5 31.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SBDS_C PF09377.10 GAM25773.1 - 5.1e-37 126.4 2.9 2e-36 124.5 0.8 2.1 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 GAM25773.1 - 3.8e-32 110.2 1.5 7.5e-32 109.3 1.5 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein PriA_C PF18074.1 GAM25773.1 - 0.051 14.4 1.5 0.093 13.6 0.6 1.9 1 1 1 2 2 2 0 Primosomal protein N C-terminal domain EB PF01683.18 GAM25774.1 - 1.2e-08 35.1 31.0 0.00013 22.2 4.8 4.2 2 2 2 4 4 4 4 EB module Dickkopf_N PF04706.12 GAM25774.1 - 0.038 14.5 30.6 0.066 13.7 9.1 3.4 3 1 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region PTEN_C2 PF10409.9 GAM25775.1 - 4.7e-10 39.3 3.3 9.7e-10 38.3 3.3 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 GAM25775.1 - 7.3e-08 32.3 0.2 2.4e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 GAM25775.1 - 6.2e-05 22.7 0.1 0.00012 21.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 GAM25775.1 - 0.00085 19.0 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAM25775.1 - 0.0013 18.8 0.0 0.0056 16.8 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 GAM25775.1 - 0.01 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family WD40 PF00400.32 GAM25776.1 - 1e-22 80.0 13.9 1.9e-06 28.5 0.4 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM25776.1 - 3.8e-09 36.7 0.1 0.15 12.4 0.0 5.4 2 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM25776.1 - 0.016 14.5 0.7 0.11 11.8 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain BBS2_Mid PF14783.6 GAM25776.1 - 0.044 13.8 0.0 8.8 6.4 0.0 3.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 GAM25776.1 - 0.1 10.9 0.0 1.1 7.5 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Roc PF08477.13 GAM25777.1 - 4e-07 30.3 0.3 1.2e-06 28.7 0.0 2.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM25777.1 - 6.1e-07 29.2 0.6 6.6e-05 22.6 0.1 2.3 2 0 0 2 2 2 2 Ras family Arf PF00025.21 GAM25777.1 - 0.00021 20.8 0.3 0.01 15.3 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM25777.1 - 0.0008 19.5 0.2 0.0025 17.9 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAM25777.1 - 0.0062 16.0 0.1 0.029 13.8 0.0 2.2 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit TMEM51 PF15345.6 GAM25777.1 - 0.031 14.1 0.5 0.053 13.4 0.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Laps PF10169.9 GAM25777.1 - 4.1 8.0 9.2 0.2 12.3 2.2 2.3 3 0 0 3 3 3 0 Learning-associated protein PBP1_TM PF14812.6 GAM25778.1 - 0.059 13.7 11.0 1.3 9.4 4.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3446 PF11928.8 GAM25778.1 - 5.6 7.3 16.3 6.8 7.1 7.0 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF4419 PF14388.6 GAM25779.1 - 9.1e-95 317.5 0.0 1.2e-94 317.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) AAA_18 PF13238.6 GAM25780.1 - 3.2e-11 43.9 0.2 1.5e-10 41.7 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 GAM25780.1 - 7.8e-10 39.3 0.0 1.7e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAM25780.1 - 4.1e-06 27.0 0.0 2.2e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 GAM25780.1 - 0.00093 18.9 0.0 0.0027 17.4 0.0 1.8 1 1 1 2 2 2 1 Dephospho-CoA kinase dNK PF01712.19 GAM25780.1 - 0.005 16.7 0.0 0.82 9.5 0.0 2.3 2 0 0 2 2 2 2 Deoxynucleoside kinase HA2 PF04408.23 GAM25782.1 - 8.7e-22 77.4 0.0 8.7e-22 77.4 0.0 3.7 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAM25782.1 - 2.4e-18 66.3 0.0 7.2e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAM25782.1 - 6.8e-18 65.0 0.0 2.7e-17 63.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM25782.1 - 6e-07 29.4 0.2 6e-07 29.4 0.2 2.4 2 1 0 2 2 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAM25782.1 - 0.00041 20.6 0.0 0.00041 20.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain TFIIA PF03153.13 GAM25782.1 - 0.0022 18.0 27.0 0.0039 17.2 27.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Flavi_DEAD PF07652.14 GAM25782.1 - 0.024 14.6 0.3 0.054 13.5 0.1 1.7 2 0 0 2 2 1 0 Flavivirus DEAD domain Presenilin PF01080.17 GAM25782.1 - 0.037 12.8 13.6 0.053 12.3 13.6 1.2 1 0 0 1 1 1 0 Presenilin ResIII PF04851.15 GAM25782.1 - 0.2 11.6 16.5 0.3 11.0 0.4 3.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF3292 PF11696.8 GAM25782.1 - 0.55 8.5 11.2 0.7 8.2 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DDHD PF02862.17 GAM25782.1 - 1.3 9.1 9.5 2.7 8.1 9.5 1.5 1 0 0 1 1 1 0 DDHD domain Bul1_N PF04425.12 GAM25782.1 - 3 6.5 16.2 5.9 5.5 16.2 1.4 1 0 0 1 1 1 0 Bul1 N terminus SpoIIP PF07454.11 GAM25782.1 - 3.9 6.8 16.4 8.1 5.8 16.4 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Ndc1_Nup PF09531.10 GAM25782.1 - 4.6 5.8 14.3 7.6 5.1 14.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPT16 PF08644.11 GAM25783.1 - 0.053 13.7 4.4 0.65 10.2 2.7 2.3 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) APG6 PF04111.12 GAM25784.1 - 8.2e-46 156.2 0.2 4e-45 154.0 0.2 2.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 GAM25784.1 - 2.2e-06 28.3 8.9 2.2e-06 28.3 8.9 2.8 3 0 0 3 3 3 1 Apg6 coiled-coil region Fes1 PF08609.10 GAM25785.1 - 2.9e-08 34.5 2.7 1.1e-07 32.7 0.2 3.1 2 2 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.23 GAM25785.1 - 0.00066 19.6 0.5 0.25 11.5 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAM25785.1 - 0.1 13.0 0.6 0.48 10.8 0.0 2.6 3 1 1 4 4 4 0 HEAT repeats HSP70 PF00012.20 GAM25786.1 - 5.1e-137 457.6 4.3 1e-136 456.6 4.3 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM25786.1 - 7.1e-13 48.1 0.1 1.5e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Peptidase_M10_C PF08548.11 GAM25787.1 - 0.045 13.6 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal PSI_PsaH PF03244.14 GAM25788.1 - 0.077 12.5 0.1 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VI Acetyltransf_7 PF13508.7 GAM25790.1 - 2.9e-08 34.0 0.0 5.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM25790.1 - 6e-08 32.9 0.0 1.5e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 GAM25790.1 - 1.7e-07 31.4 0.1 5.3e-07 29.8 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM25790.1 - 2.7e-06 27.3 0.0 6.1e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM25790.1 - 0.019 15.1 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 GAM25790.1 - 0.061 12.8 0.1 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative acetyl-transferase AFG1_ATPase PF03969.16 GAM25791.1 - 2.4e-108 362.3 0.5 2.2e-104 349.2 0.0 2.1 1 1 0 2 2 2 2 AFG1-like ATPase AAA_14 PF13173.6 GAM25791.1 - 0.00081 19.4 0.0 0.013 15.5 0.0 2.6 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM25791.1 - 0.001 19.5 0.2 0.14 12.5 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Bac_DnaA PF00308.18 GAM25791.1 - 0.0015 18.4 2.6 0.75 9.6 0.1 2.9 3 1 0 3 3 3 2 Bacterial dnaA protein Poty_PP PF08440.10 GAM25791.1 - 0.019 14.0 0.0 0.044 12.9 0.0 1.5 1 1 0 1 1 1 0 Potyviridae polyprotein AAA_22 PF13401.6 GAM25791.1 - 0.021 15.1 0.1 0.22 11.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 GAM25791.1 - 0.027 14.9 0.5 0.35 11.3 0.0 3.0 3 1 0 3 3 3 0 RNA helicase AAA PF00004.29 GAM25791.1 - 0.13 12.7 0.0 2.7 8.4 0.0 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 GAM25791.1 - 0.18 11.7 0.7 1.2 9.0 0.0 2.6 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Cupin_8 PF13621.6 GAM25792.1 - 4.1e-77 259.3 0.9 5.2e-77 259.0 0.9 1.1 1 0 0 1 1 1 1 Cupin-like domain DUF2040 PF09745.9 GAM25793.1 - 8e-33 113.1 21.2 8e-33 113.1 21.2 3.4 3 2 2 5 5 5 1 Coiled-coil domain-containing protein 55 (DUF2040) Tim17 PF02466.19 GAM25794.1 - 1.8e-09 37.9 8.1 2.4e-09 37.5 8.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.6 GAM25794.1 - 0.0043 16.8 22.3 1.4 8.7 0.2 3.9 3 1 0 3 3 3 3 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 GAM25794.1 - 0.03 14.1 5.4 0.03 14.1 5.4 2.7 2 1 0 2 2 2 0 YMGG-like Gly-zipper DUF3482 PF11981.8 GAM25794.1 - 0.039 13.3 2.3 1.2 8.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) DUF1269 PF06897.12 GAM25794.1 - 0.054 13.8 8.8 1.6 9.1 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) DUF3169 PF11368.8 GAM25794.1 - 0.48 9.9 1.7 4.2 6.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) AJAP1_PANP_C PF15298.6 GAM25795.1 - 0.0033 17.7 2.2 0.006 16.8 2.2 1.4 1 0 0 1 1 1 1 AJAP1/PANP C-terminus Dicty_REP PF05086.12 GAM25795.1 - 0.017 13.2 2.0 0.021 12.9 2.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4525 PF15027.6 GAM25795.1 - 0.052 13.3 1.5 0.11 12.3 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Menin PF05053.13 GAM25795.1 - 0.25 9.7 1.5 0.3 9.4 1.5 1.1 1 0 0 1 1 1 0 Menin BSP_II PF05432.11 GAM25795.1 - 0.43 10.2 10.6 0.55 9.9 10.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MGC-24 PF05283.11 GAM25795.1 - 1.4 9.3 10.0 2.2 8.7 10.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FtsH_ext PF06480.15 GAM25795.1 - 2.9 8.3 6.5 0.53 10.7 1.9 2.2 2 0 0 2 2 2 0 FtsH Extracellular SSP160 PF06933.11 GAM25795.1 - 4.5 5.3 13.1 6.7 4.8 13.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UPF0242 PF06785.11 GAM25795.1 - 5.3 7.1 11.4 4 7.5 8.1 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_S9 PF00326.21 GAM25796.1 - 1.4e-36 126.0 0.0 5.7e-36 124.0 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 GAM25796.1 - 2.4e-07 30.8 0.0 5.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM25796.1 - 3.1e-07 29.9 0.1 0.0012 18.1 0.2 2.3 1 1 0 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 GAM25796.1 - 1.1e-06 27.5 0.5 0.059 12.0 0.1 3.6 3 1 0 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 GAM25796.1 - 5.9e-06 26.1 0.1 0.0019 17.9 0.2 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 GAM25796.1 - 6.5e-05 22.9 0.0 0.00033 20.7 0.0 2.1 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 GAM25796.1 - 0.00035 20.3 0.0 0.0091 15.6 0.0 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 GAM25796.1 - 0.0016 18.0 0.0 0.016 14.8 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 GAM25796.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 GAM25796.1 - 0.032 14.8 0.1 0.067 13.8 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Enolase_C PF00113.22 GAM25796.1 - 0.19 10.9 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Glyoxalase_4 PF13669.6 GAM25797.1 - 3.6e-19 69.1 0.0 4.4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 GAM25797.1 - 8.1e-11 42.2 0.0 9.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 GAM25797.1 - 1e-05 25.7 0.0 1.2e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Citrate_synt PF00285.21 GAM25798.1 - 2.9e-106 355.6 0.0 3.4e-106 355.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain PAS_3 PF08447.12 GAM25798.1 - 0.079 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 PAS fold Thioredoxin PF00085.20 GAM25799.1 - 9.4e-67 221.5 4.7 3.3e-34 116.9 0.8 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 GAM25799.1 - 1.3e-24 86.9 1.0 2.9e-24 85.8 1.0 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 GAM25799.1 - 9.4e-17 61.3 0.3 4.1e-09 36.2 0.1 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GAM25799.1 - 8.3e-12 45.5 3.9 2.8e-06 27.7 0.3 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAM25799.1 - 4.6e-10 39.7 0.5 0.00044 20.5 0.1 3.5 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 GAM25799.1 - 7.1e-10 38.9 0.8 3.9e-05 23.8 0.2 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 GAM25799.1 - 5.9e-09 35.9 0.8 0.00068 19.5 0.1 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 GAM25799.1 - 0.00038 20.2 3.5 0.066 12.9 0.3 2.8 2 1 0 2 2 2 2 Redoxin Pox_G5 PF04599.12 GAM25799.1 - 0.0017 17.5 0.4 0.0092 15.0 0.1 1.9 2 0 0 2 2 2 1 Poxvirus G5 protein DDE_Tnp_1_2 PF13586.6 GAM25799.1 - 0.0069 16.7 0.0 9.7 6.6 0.0 3.4 2 1 1 3 3 3 1 Transposase DDE domain RSN1_7TM PF02714.15 GAM25799.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate HyaE PF07449.11 GAM25799.1 - 0.033 14.2 0.0 7.7 6.5 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE LOH1CR12 PF10158.9 GAM25799.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor protein Glutaredoxin PF00462.24 GAM25799.1 - 3.1 8.1 5.7 18 5.7 0.4 3.0 2 1 0 2 2 2 0 Glutaredoxin PA28_beta PF02252.18 GAM25800.1 - 4.9e-48 162.5 1.3 6.7e-48 162.0 1.3 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 GAM25800.1 - 0.0072 16.3 1.0 0.12 12.4 0.2 2.5 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit HTH_Crp_2 PF13545.6 GAM25800.1 - 0.14 12.1 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain IF4E PF01652.18 GAM25801.1 - 7.8e-41 139.5 0.1 1.1e-40 139.0 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PH PF00169.29 GAM25802.1 - 5e-05 23.8 0.1 0.00016 22.2 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 GAM25802.1 - 0.00055 20.3 0.1 0.007 16.8 0.1 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain LysM PF01476.20 GAM25802.1 - 0.00075 19.5 0.2 0.0021 18.1 0.2 1.9 1 0 0 1 1 1 1 LysM domain TAP_C PF03943.13 GAM25802.1 - 0.0009 18.8 0.0 0.0023 17.5 0.0 1.7 1 0 0 1 1 1 1 TAP C-terminal domain PH_8 PF15409.6 GAM25802.1 - 0.002 18.4 0.0 0.0049 17.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain UBA_4 PF14555.6 GAM25802.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain Opiods_neuropep PF01160.18 GAM25802.1 - 0.064 13.4 1.1 0.18 11.9 1.1 1.8 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide CHORD PF04968.12 GAM25802.1 - 4 8.2 8.0 4.5 8.1 6.4 2.1 2 0 0 2 2 2 0 CHORD ArsA_ATPase PF02374.15 GAM25803.1 - 2.7e-100 335.5 0.3 3.4e-100 335.2 0.3 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 GAM25803.1 - 2.8e-12 46.9 0.1 1.3e-11 44.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 GAM25803.1 - 3.9e-12 46.3 0.0 8.5e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 GAM25803.1 - 2.3e-06 27.3 2.2 0.00025 20.6 0.1 2.8 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 GAM25803.1 - 1.8e-05 24.3 0.0 3.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 GAM25803.1 - 4.8e-05 22.9 0.1 0.00017 21.1 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 GAM25803.1 - 0.00079 19.1 0.1 0.0026 17.4 0.1 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 GAM25803.1 - 0.015 14.5 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 GAM25803.1 - 0.023 14.3 0.0 0.058 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAM25803.1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 GAM25803.1 - 0.088 12.2 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Elf1 PF05129.13 GAM25803.1 - 0.1 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF2009 PF09418.10 GAM25804.1 - 7.3e-197 654.9 0.5 8.8e-197 654.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 GAM25804.1 - 3.5e-07 30.2 5.5 8.8e-07 29.0 5.5 1.7 1 0 0 1 1 1 1 B-box zinc finger Tat PF00539.18 GAM25804.1 - 0.11 12.7 0.5 0.3 11.3 0.5 1.7 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) Secretin_N_2 PF07655.13 GAM25804.1 - 1.1 9.9 21.4 5.2 7.7 1.5 3.0 2 0 0 2 2 2 0 Secretin N-terminal domain Bact_lectin PF18483.1 GAM25805.1 - 5.5e-24 85.3 0.0 1.1e-23 84.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 GAM25805.1 - 4.1e-21 75.6 0.0 6.8e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Legume lectin domain Rad4 PF03835.15 GAM25805.1 - 1.6e-13 50.5 1.8 3.4e-13 49.5 1.8 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 GAM25805.1 - 7.1e-13 49.0 0.0 3.5e-12 46.8 0.1 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily Lectin_leg-like PF03388.13 GAM25805.1 - 3.2e-09 36.5 0.1 5.1e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family ubiquitin PF00240.23 GAM25805.1 - 5.9e-08 32.4 0.4 1.3e-07 31.3 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin family PAW PF04721.17 GAM25805.1 - 0.037 13.8 0.7 0.081 12.7 0.7 1.5 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW Arf PF00025.21 GAM25807.1 - 2.2e-61 206.3 1.4 2.6e-61 206.1 1.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM25807.1 - 1.3e-12 48.0 0.0 1.9e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM25807.1 - 3e-12 46.5 0.0 3.5e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAM25807.1 - 1.3e-10 41.0 0.2 1.7e-10 40.6 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAM25807.1 - 1.7e-06 27.5 1.3 0.00042 19.6 0.5 2.8 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAM25807.1 - 6.2e-05 22.5 0.1 7.7e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM25807.1 - 0.00011 22.3 0.1 0.00014 21.9 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GAM25807.1 - 0.0023 18.2 0.1 0.0036 17.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 GAM25807.1 - 0.0046 16.5 0.6 0.27 10.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 GAM25807.1 - 0.015 15.3 0.1 0.023 14.7 0.1 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM25807.1 - 0.13 12.8 0.2 0.2 12.2 0.2 1.4 1 1 0 1 1 1 0 ABC transporter ParA PF10609.9 GAM25810.1 - 1.1e-91 306.7 0.0 1.3e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAM25810.1 - 7.2e-15 55.2 0.0 1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAM25810.1 - 1.5e-09 38.0 0.2 1.1e-08 35.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 GAM25810.1 - 3.8e-07 29.6 1.4 1.5e-06 27.6 0.2 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 GAM25810.1 - 1.5e-06 27.7 0.1 4.9e-06 26.0 0.1 1.8 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 GAM25810.1 - 5.3e-05 22.8 0.0 0.00028 20.4 0.1 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 GAM25810.1 - 0.00012 21.7 0.0 0.00067 19.2 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 GAM25810.1 - 0.00022 20.3 0.1 0.00034 19.7 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 GAM25810.1 - 0.00089 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase CLP1_P PF16575.5 GAM25810.1 - 0.00094 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 GAM25810.1 - 0.0043 16.7 0.0 0.063 12.9 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 GAM25810.1 - 0.0073 15.5 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain GFO_IDH_MocA PF01408.22 GAM25810.1 - 0.0074 17.1 0.0 4.7 8.1 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold AAA_25 PF13481.6 GAM25810.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAM25810.1 - 0.013 15.4 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_26 PF13500.6 GAM25810.1 - 0.016 15.0 0.1 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAM25810.1 - 0.051 13.8 0.2 0.34 11.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain VirC1 PF07015.11 GAM25810.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein AAA_16 PF13191.6 GAM25810.1 - 0.11 12.9 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 GAM25810.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 GAM25810.1 - 0.13 12.0 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 GAM25810.1 - 0.21 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 GAM25810.1 - 0.28 11.1 0.6 0.65 9.9 0.2 1.7 2 0 0 2 2 2 0 NTPase HSP20 PF00011.21 GAM25811.1 - 2.1e-22 79.2 0.1 2.7e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM25811.1 - 1.6e-08 33.9 0.0 2.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA VCBS PF13517.6 GAM25812.1 - 0.00034 21.1 0.1 0.065 13.8 0.0 2.9 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAM25812.1 - 0.0098 16.0 5.2 0.027 14.6 0.3 2.8 2 0 0 2 2 2 1 FG-GAP repeat PQQ_2 PF13360.6 GAM25812.1 - 0.013 15.1 0.2 8.8 5.8 0.0 3.9 3 1 0 3 3 3 0 PQQ-like domain Ribosomal_L13 PF00572.18 GAM25813.1 - 1e-11 45.2 0.1 1.2e-09 38.4 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 PhoLip_ATPase_C PF16212.5 GAM25814.1 - 1.6e-77 260.6 27.4 1.6e-77 260.6 27.4 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM25814.1 - 1.5e-25 88.7 4.0 1.5e-25 88.7 4.0 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 GAM25814.1 - 5.8e-09 35.7 4.2 1.5e-08 34.4 0.0 3.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM25814.1 - 1e-08 35.7 0.3 0.00031 21.1 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM25814.1 - 2.9e-08 33.7 0.0 1.2e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAM25814.1 - 0.0067 16.2 0.1 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase p450 PF00067.22 GAM25815.1 - 2.2e-92 310.3 0.0 2.4e-92 310.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RCC1 PF00415.18 GAM25816.1 - 1.1e-68 227.6 23.0 1.1e-13 51.6 0.3 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 GAM25816.1 - 4.8e-52 177.4 0.0 8.9e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 GAM25816.1 - 1.3e-36 126.4 0.3 7e-36 123.9 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain RCC1_2 PF13540.6 GAM25816.1 - 1.7e-29 101.0 38.0 6.9e-08 32.1 0.3 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 GAM25816.1 - 2.4e-23 82.7 0.0 9.5e-23 80.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM25816.1 - 0.0044 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM25816.1 - 0.012 15.0 3.2 0.031 13.6 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YopX PF09643.10 GAM25816.1 - 0.081 13.0 0.1 0.081 13.0 0.1 2.0 2 0 0 2 2 2 0 YopX protein FNIP PF05725.12 GAM25817.1 - 2.4e-70 232.5 21.4 8.6e-15 54.6 0.8 8.1 8 0 0 8 8 8 7 FNIP Repeat HTH_ABP1_N PF18107.1 GAM25817.1 - 0.05 13.3 0.4 0.75 9.6 0.0 2.8 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain RhoGEF PF00621.20 GAM25818.1 - 7.9e-76 254.4 15.5 6.4e-47 160.1 4.1 2.6 2 0 0 2 2 2 2 RhoGEF domain RhoGAP PF00620.27 GAM25818.1 - 2.1e-43 147.7 0.3 4e-42 143.6 0.1 2.7 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.6 GAM25818.1 - 5e-12 45.5 0.2 8.7e-12 44.7 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM25818.1 - 2.6e-09 36.5 0.1 4.9e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM25818.1 - 3.9e-08 32.8 0.0 9.5e-08 31.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF1708 PF08101.11 GAM25818.1 - 0.00029 20.1 0.1 0.00054 19.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) PH PF00169.29 GAM25818.1 - 0.002 18.6 0.5 0.0069 16.9 0.3 2.0 2 0 0 2 2 2 1 PH domain FHA PF00498.26 GAM25819.1 - 1.9e-05 24.9 0.0 4.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain JUPITER PF17054.5 GAM25819.1 - 4.1 6.8 16.3 1 8.8 8.8 2.1 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter zf-HIT PF04438.16 GAM25821.1 - 1.1e-06 28.4 11.4 1.7e-06 27.8 11.4 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF2826 PF11442.8 GAM25821.1 - 0.039 13.8 0.1 0.084 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) DUF2457 PF10446.9 GAM25821.1 - 0.067 12.3 8.6 0.1 11.8 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-MYND PF01753.18 GAM25821.1 - 0.097 12.8 12.0 0.2 11.8 12.0 1.6 1 0 0 1 1 1 0 MYND finger PBP1_TM PF14812.6 GAM25821.1 - 1.2 9.6 8.5 2.6 8.5 8.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Importin_rep_6 PF18829.1 GAM25821.1 - 7.1 6.8 10.0 9.5 6.4 8.4 2.1 2 1 0 2 2 2 0 Importin repeat 6 Peptidase_C1 PF00112.23 GAM25822.1 - 1.6e-16 61.0 0.0 2.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C39_2 PF13529.6 GAM25822.1 - 0.00044 20.8 0.0 0.00097 19.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C1_2 PF03051.15 GAM25822.1 - 0.031 13.1 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase C1-like family TerB PF05099.13 GAM25822.1 - 0.086 12.8 1.3 0.15 12.0 0.4 2.0 2 1 0 2 2 2 0 Tellurite resistance protein TerB DUF287 PF03384.14 GAM25822.1 - 0.1 13.0 0.1 10 6.6 0.2 2.6 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 Pro-kuma_activ PF09286.11 GAM25824.1 - 1.8e-33 115.9 0.1 3.2e-33 115.0 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM25824.1 - 0.00024 20.5 0.5 0.00046 19.5 0.5 1.6 1 1 0 1 1 1 1 Subtilase family CDC50 PF03381.15 GAM25825.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Gpi16 PF04113.14 GAM25826.1 - 1.2e-95 321.1 0.1 1.6e-95 320.7 0.1 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LRR_4 PF12799.7 GAM25827.1 - 1.6e-24 85.6 32.6 5.6e-05 23.4 0.3 7.6 3 1 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM25827.1 - 2.7e-23 81.5 30.5 2.4e-07 30.4 4.2 6.1 3 2 3 6 6 6 5 Leucine rich repeat Pkinase_Tyr PF07714.17 GAM25827.1 - 4.1e-23 82.0 0.0 7.9e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM25827.1 - 2.8e-14 53.1 0.0 6.3e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain RGS PF00615.19 GAM25827.1 - 4.2e-12 46.4 1.5 1.4e-11 44.7 1.5 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain COR PF16095.5 GAM25827.1 - 5.3e-12 46.0 0.0 4.1e-11 43.1 0.0 2.5 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain RhoGAP PF00620.27 GAM25827.1 - 2.6e-10 40.3 3.1 7.3e-10 38.9 0.7 2.8 2 0 0 2 2 2 1 RhoGAP domain Kelch_3 PF13415.6 GAM25827.1 - 2.6e-07 30.7 1.1 0.0087 16.3 0.1 4.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM25827.1 - 4.5e-07 29.9 0.1 0.0013 19.0 0.1 3.3 2 0 0 2 2 2 2 Kelch motif Roc PF08477.13 GAM25827.1 - 1.7e-05 25.0 0.0 4.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Kelch_4 PF13418.6 GAM25827.1 - 3e-05 24.0 0.2 0.0051 16.8 0.1 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM25827.1 - 6.4e-05 22.8 0.0 0.0097 15.9 0.0 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 GAM25827.1 - 0.00017 21.4 0.2 0.0018 18.2 0.1 2.5 2 0 0 2 2 2 1 Kelch motif RGS-like PF09128.11 GAM25827.1 - 0.0032 17.2 0.5 0.007 16.1 0.5 1.5 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain DUF1759 PF03564.15 GAM25827.1 - 0.023 14.6 0.8 0.2 11.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) LRR_9 PF14580.6 GAM25827.1 - 0.072 12.6 15.2 1.6 8.2 4.3 3.7 1 1 2 3 3 3 0 Leucine-rich repeat AAA_16 PF13191.6 GAM25827.1 - 0.15 12.5 0.0 0.56 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain LRR_1 PF00560.33 GAM25827.1 - 0.45 11.3 19.6 19 6.3 0.2 8.6 9 0 0 9 9 7 0 Leucine Rich Repeat Nucleo_P87 PF07267.11 GAM25827.1 - 4.7 5.9 12.2 8.9 5.0 12.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Rer1 PF03248.13 GAM25828.1 - 2.3e-64 216.3 5.0 2.6e-64 216.0 5.0 1.0 1 0 0 1 1 1 1 Rer1 family DUF3742 PF12553.8 GAM25828.1 - 0.39 10.8 1.8 1.4 9.0 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) DUF1980 PF09323.10 GAM25828.1 - 0.88 9.5 5.2 0.23 11.4 1.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) DUF2208 PF09973.9 GAM25828.1 - 0.88 9.1 8.0 0.051 13.2 3.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) WD40 PF00400.32 GAM25829.1 - 5.8e-37 125.1 12.3 9.9e-07 29.4 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM25829.1 - 1.9e-17 63.3 0.0 0.037 14.3 0.0 5.8 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM25829.1 - 3.5e-08 32.8 3.0 0.021 13.8 0.4 3.9 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein CSTF1_dimer PF16699.5 GAM25829.1 - 2.3e-06 27.2 0.0 5.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain Cytochrom_D1 PF02239.16 GAM25829.1 - 2.7e-05 22.9 0.0 0.0017 17.0 0.0 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.11 GAM25829.1 - 0.00034 20.6 1.8 0.057 13.3 0.1 3.5 2 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Glycophorin_A PF01102.18 GAM25830.1 - 0.0063 16.7 0.1 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Glycophorin A CbiM PF01891.16 GAM25830.1 - 0.19 11.5 3.1 0.32 10.8 3.1 1.3 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region DUF5123 PF17161.4 GAM25830.1 - 0.35 12.0 11.9 0.89 10.7 1.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5123) LRR_5 PF13306.6 GAM25830.1 - 6.6 6.7 14.3 0.41 10.6 3.4 3.2 2 1 2 4 4 4 0 BspA type Leucine rich repeat region (6 copies) SET PF00856.28 GAM25831.1 - 1.2e-16 61.5 0.0 2.4e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 SET domain zf-HIT PF04438.16 GAM25831.1 - 0.004 17.0 3.3 0.004 17.0 3.3 2.7 3 0 0 3 3 3 1 HIT zinc finger Glyco_hydro_42 PF02449.15 GAM25831.1 - 0.017 14.5 0.1 0.048 13.0 0.0 1.7 1 1 0 1 1 1 0 Beta-galactosidase RNA_GG_bind PF10258.9 GAM25832.1 - 5.1e-11 42.5 0.9 3.3e-09 36.7 0.9 2.6 1 1 0 1 1 1 1 PHAX RNA-binding domain TFIIA PF03153.13 GAM25832.1 - 0.051 13.6 17.2 0.086 12.8 17.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4776 PF16003.5 GAM25832.1 - 0.85 8.6 15.1 1.1 8.2 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF4407 PF14362.6 GAM25832.1 - 1.5 8.1 5.1 2.6 7.3 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-ZPR1 PF03367.13 GAM25832.1 - 2.5 8.0 11.4 1.2 9.0 7.6 2.3 2 1 0 2 2 2 0 ZPR1 zinc-finger domain Glycophorin_A PF01102.18 GAM25832.1 - 8.2 6.7 9.6 0.51 10.6 0.2 2.8 2 1 0 2 2 2 0 Glycophorin A DUF885 PF05960.11 GAM25833.1 - 0.032 13.9 0.1 0.037 13.7 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Spore_II_R PF09551.10 GAM25833.1 - 0.059 13.8 0.1 0.072 13.5 0.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) DUF1682 PF07946.14 GAM25833.1 - 7.7 5.6 9.6 8.3 5.5 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FliD_N PF02465.18 GAM25834.1 - 0.0074 17.0 22.3 0.13 12.9 3.4 5.0 3 1 3 6 6 6 3 Flagellar hook-associated protein 2 N-terminus Vps5 PF09325.10 GAM25834.1 - 1.1 8.8 32.7 0.032 13.8 2.4 4.5 2 1 2 4 4 4 0 Vps5 C terminal like BLM10_mid PF16507.5 GAM25835.1 - 2.6e-61 207.9 3.6 2.6e-61 207.9 3.6 3.7 3 1 0 3 3 3 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 GAM25835.1 - 4.8e-26 90.5 2.3 2.4e-25 88.3 0.4 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) CLASP_N PF12348.8 GAM25835.1 - 7.7e-08 32.2 1.4 7.5e-05 22.4 0.1 4.3 3 1 1 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 GAM25835.1 - 0.0011 19.1 2.3 1.8 8.7 0.1 3.7 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 GAM25835.1 - 0.0088 16.2 0.0 6.1 7.4 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat DUF5029 PF16432.5 GAM25835.1 - 0.088 12.3 0.2 0.21 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5029) Cir_N PF10197.9 GAM25836.1 - 6.5e-13 48.6 4.8 6.5e-13 48.6 4.8 2.6 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR DNApol_Exo PF18136.1 GAM25836.1 - 4.7 6.3 7.7 0.4 9.8 1.5 2.0 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain Sad1_UNC PF07738.13 GAM25837.1 - 2.4e-20 72.9 0.0 5.3e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ANTH PF07651.16 GAM25837.1 - 0.012 14.7 1.1 0.02 13.9 1.1 1.3 1 0 0 1 1 1 0 ANTH domain Nre_C PF04895.12 GAM25837.1 - 0.034 14.1 0.4 0.088 12.7 0.2 1.8 2 0 0 2 2 2 0 Archaeal Nre, C-terminal DUF5401 PF17380.2 GAM25837.1 - 0.08 11.0 4.7 0.12 10.4 4.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) AAA_assoc_C PF09821.9 GAM25837.1 - 0.099 13.2 2.8 0.23 12.0 0.1 2.4 2 0 0 2 2 2 0 C-terminal AAA-associated domain DUF3678 PF12435.8 GAM25837.1 - 3.4 7.1 9.4 5.7 6.4 3.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) AIM24 PF01987.17 GAM25838.1 - 8.3e-57 192.2 1.4 8.3e-57 192.2 1.4 1.5 2 0 0 2 2 2 1 Mitochondrial biogenesis AIM24 Ank_2 PF12796.7 GAM25839.1 - 2.4e-48 162.6 10.3 5.4e-14 52.5 0.6 5.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 GAM25839.1 - 1.4e-40 136.0 12.1 2e-05 24.8 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 GAM25839.1 - 2.4e-39 128.8 7.9 5.5e-05 23.3 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 GAM25839.1 - 2.6e-39 133.1 4.8 6.2e-09 36.2 0.1 7.3 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM25839.1 - 3.2e-35 119.7 25.5 3.6e-09 36.7 0.0 8.5 3 1 5 9 9 9 7 Ankyrin repeats (many copies) F-box PF00646.33 GAM25839.1 - 8.4e-09 35.1 0.1 2.7e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAM25839.1 - 7.8e-08 32.1 0.1 1.7e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 F-box-like LOH1CR12 PF10158.9 GAM25840.1 - 0.0054 16.8 0.4 0.011 15.8 0.4 1.4 1 0 0 1 1 1 1 Tumour suppressor protein Myotub-related PF06602.14 GAM25841.1 - 1.2e-58 198.8 0.4 4.9e-58 196.7 0.1 2.1 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Pkinase_Tyr PF07714.17 GAM25841.1 - 8.4e-36 123.6 0.0 1.6e-32 112.8 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAM25841.1 - 1.3e-28 100.1 0.0 5e-25 88.4 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 GAM25841.1 - 1.5e-23 82.3 34.4 1.7e-07 30.9 6.3 6.7 2 1 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 GAM25841.1 - 2.4e-23 81.8 37.6 6.9e-05 23.1 1.7 7.2 2 2 3 7 7 7 6 Leucine Rich repeats (2 copies) COR PF16095.5 GAM25841.1 - 3.6e-10 40.0 0.0 4e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 GAM25841.1 - 3.2e-09 37.0 0.0 9.7e-09 35.5 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_9 PF14580.6 GAM25841.1 - 0.00024 20.6 12.6 0.00092 18.8 3.2 3.7 1 1 2 3 3 3 2 Leucine-rich repeat RsmF_methylt_CI PF17126.5 GAM25841.1 - 0.043 13.9 0.1 0.71 10.0 0.0 3.1 3 0 0 3 3 3 0 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 GAM25841.1 - 0.058 13.5 24.1 2.4 8.4 0.5 7.9 7 0 0 7 7 7 0 Leucine Rich repeat Dicty_REP PF05086.12 GAM25841.1 - 0.16 10.0 10.6 0.36 8.8 10.6 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 GAM25841.1 - 1.4 8.9 13.7 2.3 8.2 11.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAM25841.1 - 1.5 8.8 24.8 0.32 11.0 20.6 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein MOR2-PAG1_C PF14225.6 GAM25842.1 - 1.4e-19 71.0 0.0 9.5e-19 68.2 0.0 2.5 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_N PF14222.6 GAM25842.1 - 7.2e-19 68.2 3.7 1e-12 47.8 0.1 3.0 2 0 0 2 2 2 2 Cell morphogenesis N-terminal RGS PF00615.19 GAM25842.1 - 4.7e-07 30.1 0.0 1.6e-06 28.3 0.0 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain V_ATPase_I PF01496.19 GAM25842.1 - 0.015 13.3 1.7 0.028 12.4 1.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HORMA PF02301.18 GAM25842.1 - 5.1 6.6 6.6 0.55 9.8 0.0 2.7 3 0 0 3 3 3 0 HORMA domain RabGAP-TBC PF00566.18 GAM25843.1 - 4.6e-51 173.5 0.2 4.6e-51 173.5 0.2 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 GAM25843.1 - 1.7e-24 85.9 7.5 5.6e-15 55.2 3.8 2.9 2 0 0 2 2 2 2 GRAM domain EF-hand_1 PF00036.32 GAM25843.1 - 1.9e-07 30.1 6.8 0.0038 16.7 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 GAM25843.1 - 2.9e-07 30.8 5.6 9e-07 29.3 3.2 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM25843.1 - 5.6e-07 29.0 3.0 0.012 15.5 0.2 3.4 3 0 0 3 3 3 2 EF-hand domain Takusan PF04822.13 GAM25843.1 - 0.028 14.3 0.8 3.2 7.7 0.0 2.8 2 0 0 2 2 2 0 Takusan EF-hand_8 PF13833.6 GAM25843.1 - 0.095 12.6 4.9 0.16 11.8 2.8 2.5 1 1 1 2 2 2 0 EF-hand domain pair EGF_2 PF07974.13 GAM25844.1 - 8.4e-06 26.1 27.0 0.0034 17.7 7.9 2.8 1 1 1 2 2 2 2 EGF-like domain hEGF PF12661.7 GAM25844.1 - 0.52 11.0 20.8 4.2 8.2 6.9 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.13 GAM25845.1 - 2.6e-05 24.5 25.9 0.018 15.4 7.3 2.7 1 1 1 2 2 2 2 EGF-like domain PGM_PMM_IV PF00408.20 GAM25845.1 - 0.022 14.9 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain hEGF PF12661.7 GAM25845.1 - 0.2 12.3 21.4 0.96 10.2 7.7 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF TMEM154 PF15102.6 GAM25845.1 - 9.2 6.2 10.6 20 5.1 10.6 1.6 1 0 0 1 1 1 0 TMEM154 protein family LRR_4 PF12799.7 GAM25846.1 - 2.1e-22 78.8 73.2 0.0063 16.9 0.4 16.9 4 3 14 21 21 21 18 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAM25846.1 - 6.6e-09 35.1 65.0 1.1 9.5 0.0 20.0 21 0 0 21 21 21 7 Leucine Rich repeat DUF1699 PF08004.11 GAM25846.1 - 0.0043 16.7 12.1 8.7 6.0 0.0 6.7 5 2 2 7 7 7 3 Protein of unknown function (DUF1699) RmuC PF02646.16 GAM25847.1 - 0.013 14.6 0.2 0.013 14.6 0.2 2.3 2 0 0 2 2 2 0 RmuC family AAA_28 PF13521.6 GAM25847.1 - 0.02 15.1 0.5 0.055 13.7 0.5 1.7 1 0 0 1 1 1 0 AAA domain CDC27 PF09507.10 GAM25847.1 - 1.7 7.9 36.5 0.45 9.9 15.0 2.6 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Peptidase_M8 PF01457.16 GAM25848.1 - 4.9e-36 124.5 0.1 5.4e-36 124.4 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF3294 PF07957.11 GAM25849.1 - 0.057 13.2 0.1 0.067 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) NAGLU PF05089.12 GAM25850.1 - 2e-139 464.2 9.8 2.7e-139 463.8 9.8 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 GAM25850.1 - 1.3e-70 238.0 7.2 1.8e-70 237.6 7.2 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 GAM25850.1 - 3.3e-17 62.0 0.0 7.3e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain ABC_membrane PF00664.23 GAM25851.1 - 1.3e-57 195.5 28.4 1.3e-57 195.5 28.4 2.5 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAM25851.1 - 2e-34 119.0 0.0 4.6e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAM25851.1 - 1.4e-06 28.0 0.9 0.00052 19.5 0.1 2.6 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM25851.1 - 0.0085 15.8 0.2 0.028 14.2 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM25851.1 - 0.0097 15.8 0.0 0.03 14.2 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 GAM25851.1 - 0.023 14.5 0.1 0.52 10.1 0.1 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAM25851.1 - 0.043 13.5 0.2 0.075 12.7 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAM25851.1 - 0.051 13.9 0.3 0.4 11.0 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAM25851.1 - 0.17 11.4 0.3 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAM25851.1 - 0.22 12.0 0.2 0.22 12.0 0.2 1.7 2 0 0 2 2 1 0 AAA domain DUF3754 PF12576.8 GAM25851.1 - 5.9 6.8 9.9 1.2 9.1 0.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3754) UPF0242 PF06785.11 GAM25852.1 - 0.0041 17.2 1.0 0.0041 17.2 1.0 1.9 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Spt20 PF12090.8 GAM25852.1 - 2 8.0 17.2 0.1 12.2 9.8 2.2 2 0 0 2 2 2 0 Spt20 family Actin PF00022.19 GAM25853.1 - 4e-152 506.5 0.0 1.3e-151 504.9 0.0 1.6 1 1 0 1 1 1 1 Actin Presenilin PF01080.17 GAM25854.1 - 3e-127 424.7 11.1 4.1e-84 282.7 6.9 3.0 1 1 2 3 3 3 2 Presenilin Pex14_N PF04695.13 GAM25854.1 - 0.02 15.6 8.6 0.12 13.1 2.7 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.14 GAM25854.1 - 0.022 13.1 4.3 0.044 12.1 3.6 1.6 2 0 0 2 2 2 0 CDC45-like protein SARAF PF06682.12 GAM25854.1 - 0.28 10.8 3.3 4.6 6.8 0.7 2.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Menin PF05053.13 GAM25854.1 - 1.2 7.4 3.5 2.1 6.6 3.5 1.3 1 0 0 1 1 1 0 Menin TMEM43 PF07787.12 GAM25854.1 - 3.2 7.1 5.2 92 2.3 0.0 2.9 2 0 0 2 2 2 0 Transmembrane protein 43 NUC173 PF08161.12 GAM25855.1 - 3.1e-61 206.6 0.1 2.3e-60 203.7 0.0 2.6 2 0 0 2 2 2 1 NUC173 domain FAD_binding_3 PF01494.19 GAM25857.1 - 3.3e-32 112.1 0.0 4.3e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF4470 PF14737.6 GAM25857.1 - 0.022 14.9 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) Longin PF13774.6 GAM25858.1 - 3.7e-11 42.9 0.3 7e-11 42.0 0.3 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain HMG_box PF00505.19 GAM25859.1 - 1.6e-14 54.0 1.4 1.8e-14 53.9 1.4 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAM25859.1 - 7.3e-11 42.5 0.7 7.8e-11 42.4 0.7 1.0 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 GAM25859.1 - 0.00029 20.7 0.0 0.00045 20.1 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain DEAD PF00270.29 GAM25860.1 - 1.6e-20 73.6 0.1 1.6e-20 73.6 0.1 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM25860.1 - 3e-13 50.1 1.1 2.2e-11 44.1 0.1 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SdrD_B PF17210.3 GAM25861.1 - 9.6e-71 235.1 125.8 3.4e-08 33.7 0.2 16.4 14 2 0 14 14 14 13 SdrD B-like domain DUF2012 PF09430.10 GAM25861.1 - 3.5e-05 23.9 0.0 45 4.2 0.0 7.1 8 0 0 8 8 8 1 Protein of unknown function (DUF2012) DUF1769 PF08588.10 GAM25861.1 - 0.062 13.5 3.1 8.5 6.7 0.0 4.9 6 0 0 6 6 6 0 Protein of unknown function (DUF1769) HDV_ag PF01517.18 GAM25861.1 - 0.38 10.5 10.6 20 4.9 0.1 5.7 7 0 0 7 7 7 0 Hepatitis delta virus delta antigen ArsA_ATPase PF02374.15 GAM25863.1 - 0.12 11.5 0.0 1.1 8.4 0.0 1.9 2 0 0 2 2 2 0 Anion-transporting ATPase RasGEF PF00617.19 GAM25864.1 - 4.3e-59 199.7 1.1 1.5e-58 197.9 0.2 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM25864.1 - 1.9e-28 98.7 2.1 9.2e-28 96.6 2.1 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif YhhN PF07947.14 GAM25865.1 - 6.8e-37 126.9 19.0 1e-36 126.3 19.0 1.3 1 0 0 1 1 1 1 YhhN family UPF0242 PF06785.11 GAM25865.1 - 5.1 7.2 9.0 3.6 7.6 1.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Lig_chan PF00060.26 GAM25865.1 - 6.9 6.5 7.2 15 5.4 6.3 2.1 2 1 0 2 2 2 0 Ligand-gated ion channel FNIP PF05725.12 GAM25866.1 - 6.2e-33 112.7 18.6 1.1e-11 44.7 0.1 7.0 6 1 2 8 8 8 6 FNIP Repeat Ribosomal_L24e PF01246.20 GAM25866.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L24e KTI12 PF08433.10 GAM25867.1 - 9.6e-93 310.6 0.0 1.1e-92 310.4 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAM25867.1 - 5.4e-09 36.3 0.1 1.8e-08 34.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAM25867.1 - 0.0027 17.9 0.0 0.0072 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAM25867.1 - 0.0029 18.0 0.0 0.0057 17.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 GAM25867.1 - 0.0031 16.6 0.1 0.0058 15.7 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATP_bind_1 PF03029.17 GAM25867.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 GAM25867.1 - 0.012 15.2 0.0 1.1 8.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM25867.1 - 0.017 15.7 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAM25867.1 - 0.023 14.0 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_31 PF13614.6 GAM25867.1 - 0.086 12.7 0.2 0.23 11.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 GAM25867.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 GAM25867.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 GAM25867.1 - 0.15 12.3 0.1 0.43 10.8 0.0 1.7 2 1 0 2 2 2 0 Hydin Adenylate kinase-like domain Pro_dh PF01619.18 GAM25868.1 - 2.5e-73 247.2 0.0 3.6e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase ADH_zinc_N_2 PF13602.6 GAM25869.1 - 3.6e-18 66.9 0.0 6.1e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAM25869.1 - 1.1e-15 57.8 0.1 6.2e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM25869.1 - 4.2e-10 39.5 0.4 1.4e-09 37.8 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF1722 PF08349.11 GAM25869.1 - 0.016 15.5 0.0 3.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Pox_A32 PF04665.12 GAM25869.1 - 0.045 13.2 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DUF3095 PF11294.8 GAM25869.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) adh_short PF00106.25 GAM25870.1 - 1.6e-33 115.8 0.1 2.2e-33 115.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM25870.1 - 1.1e-28 100.4 0.1 1.5e-28 100.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM25870.1 - 1.4e-05 25.1 0.1 2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 KR domain NDT80_PhoG PF05224.12 GAM25871.1 - 1.2e-21 77.8 0.1 1.2e-21 77.8 0.1 3.9 2 1 0 2 2 1 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.6 GAM25871.1 - 9.9e-11 41.8 0.0 1.9e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase MRF_C1 PF13887.6 GAM25871.1 - 7.1e-09 34.7 0.1 1.5e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 ETRAMP PF09716.10 GAM25871.1 - 7.6e-05 22.7 2.3 9.2e-05 22.4 0.2 2.1 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) DUF4179 PF13786.6 GAM25871.1 - 0.026 15.0 1.2 0.45 11.0 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF2207 PF09972.9 GAM25871.1 - 0.048 12.4 0.0 0.048 12.4 0.0 2.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) CwsA PF10814.8 GAM25871.1 - 0.064 13.4 0.8 0.43 10.7 0.0 2.5 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA HetR_C PF18460.1 GAM25871.1 - 0.17 11.8 0.4 0.39 10.7 0.4 1.5 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain DUF4337 PF14235.6 GAM25871.1 - 0.22 11.6 0.1 0.22 11.6 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) ECSCR PF15820.5 GAM25871.1 - 0.8 9.6 0.0 0.8 9.6 0.0 2.7 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF4834 PF16118.5 GAM25871.1 - 3.4 8.7 0.0 3.4 8.7 0.0 5.1 4 1 0 4 4 3 0 Domain of unknown function (DUF4834) CAF1C_H4-bd PF12265.8 GAM25872.1 - 1.4e-27 95.7 5.1 2.2e-27 95.1 1.2 2.9 3 1 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GAM25872.1 - 1.4e-24 85.9 19.4 5.8e-08 33.3 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.11 GAM25872.1 - 0.00024 21.0 0.7 0.0047 16.8 0.1 2.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 GAM25872.1 - 0.00099 19.4 1.2 0.2 12.0 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 GAM25873.1 - 2.2e-12 46.8 5.5 0.037 14.3 0.0 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM25873.1 - 3.6e-08 33.3 12.3 0.18 11.8 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM25873.1 - 2.7e-07 30.3 2.5 0.37 10.8 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 GAM25873.1 - 2.7 7.7 8.4 36 4.0 0.1 4.6 5 1 0 5 5 5 0 Kelch motif Kelch_5 PF13854.6 GAM25873.1 - 3.8 7.6 12.0 8.5 6.5 0.6 4.2 4 0 0 4 4 4 0 Kelch motif FNIP PF05725.12 GAM25874.1 - 2.9e-90 296.2 28.5 1.4e-15 57.1 0.4 10.7 8 2 4 12 12 12 11 FNIP Repeat XPG_N PF00752.17 GAM25875.1 - 2.6e-30 104.9 0.0 6e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 GAM25875.1 - 6.2e-29 100.2 0.3 1.4e-28 99.1 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 GAM25875.1 - 3.7e-06 27.4 0.1 2.9e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF3231 PF11553.8 GAM25875.1 - 0.004 16.8 0.4 0.37 10.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3231) HSCB_C PF07743.13 GAM25875.1 - 0.089 13.3 2.4 0.16 12.5 1.6 1.9 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain VPS9 PF02204.18 GAM25876.1 - 3.2e-32 110.8 0.1 8.7e-32 109.4 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 GAM25876.1 - 2.1e-08 34.3 0.0 8.6e-08 32.4 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Ras PF00071.22 GAM25877.1 - 5.1e-64 214.8 0.3 5.9e-64 214.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM25877.1 - 8.9e-36 122.7 0.3 1.4e-35 122.1 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM25877.1 - 1.6e-18 66.8 0.2 2e-18 66.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAM25877.1 - 3.7e-06 27.0 0.2 0.07 13.0 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GAM25877.1 - 7.7e-06 25.4 0.1 8.9e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM25877.1 - 3e-05 24.1 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM25877.1 - 4.1e-05 23.2 0.3 0.00016 21.3 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAM25877.1 - 5.5e-05 22.7 0.0 9.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GAM25877.1 - 0.001 18.6 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA PF00004.29 GAM25877.1 - 0.0035 17.8 0.0 2.1 8.7 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 GAM25877.1 - 0.01 16.4 0.3 0.082 13.4 0.3 2.1 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 GAM25877.1 - 0.042 14.1 0.0 0.16 12.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAM25877.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM25877.1 - 0.046 14.1 0.0 0.064 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 GAM25877.1 - 0.055 13.4 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 GAM25877.1 - 0.1 11.8 0.1 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Septin TniB PF05621.11 GAM25877.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ECH_1 PF00378.20 GAM25878.1 - 1.3e-87 293.3 0.7 1.5e-87 293.1 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM25878.1 - 7.6e-43 147.3 1.5 3.1e-37 128.8 0.4 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 GAM25878.1 - 0.0018 18.2 0.1 0.17 11.8 0.0 2.7 2 0 0 2 2 2 1 Peptidase family S49 SDH_sah PF01972.16 GAM25878.1 - 0.027 13.5 0.0 0.069 12.1 0.0 1.4 1 1 0 1 1 1 0 Serine dehydrogenase proteinase PI3_PI4_kinase PF00454.27 GAM25879.1 - 1.2e-38 133.4 0.4 4.4e-36 125.0 0.4 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 GAM25879.1 - 0.0069 15.7 0.1 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4135) Cytomega_UL84 PF06284.11 GAM25880.1 - 0.0049 15.4 5.0 0.0075 14.8 4.6 1.5 2 0 0 2 2 2 1 Cytomegalovirus UL84 protein SOG2 PF10428.9 GAM25880.1 - 0.18 11.0 25.5 0.29 10.3 25.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Cir_N PF10197.9 GAM25880.1 - 0.75 10.0 0.0 0.75 10.0 0.0 4.3 5 0 0 5 5 5 0 N-terminal domain of CBF1 interacting co-repressor CIR SseC PF04888.12 GAM25880.1 - 7.4 6.1 12.1 0.084 12.5 2.2 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family EBV-NA3 PF05009.12 GAM25880.1 - 9.8 5.6 11.6 0.55 9.7 4.1 2.1 1 1 1 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) SpoU_methylase PF00588.19 GAM25881.1 - 6.5e-27 94.4 0.0 1.2e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 GAM25881.1 - 0.00015 22.0 0.3 0.0015 18.8 0.0 2.8 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding SUIM_assoc PF16619.5 GAM25881.1 - 0.016 15.3 2.3 0.056 13.5 2.3 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Snf7 PF03357.21 GAM25882.1 - 1.6e-39 135.2 29.5 2e-39 135.0 29.5 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 GAM25882.1 - 0.0027 17.6 8.8 0.0036 17.3 8.8 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway AMP-binding_C_2 PF14535.6 GAM25882.1 - 0.31 11.4 4.5 0.15 12.4 1.4 2.0 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain Hemagglutinin PF00509.18 GAM25882.1 - 1.7 6.9 8.2 0.054 11.9 2.3 1.4 2 0 0 2 2 2 0 Haemagglutinin Cofilin_ADF PF00241.20 GAM25883.1 - 6.4e-53 177.7 0.0 6.2e-17 61.5 0.0 3.1 3 0 0 3 3 3 3 Cofilin/tropomyosin-type actin-binding protein HATPase_c PF02518.26 GAM25884.1 - 2.2e-26 92.6 0.1 4.9e-26 91.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM25884.1 - 4.5e-22 78.3 2.2 5.2e-19 68.5 0.3 2.8 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 GAM25884.1 - 2e-19 69.4 0.0 3.8e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 GAM25884.1 - 6.2e-10 39.3 0.0 4.1e-09 36.6 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 GAM25884.1 - 0.00014 21.8 0.0 0.0025 17.8 0.0 2.5 2 0 0 2 2 2 1 PAS domain FleQ PF06490.11 GAM25884.1 - 0.00047 20.5 0.1 0.48 10.8 0.0 2.9 3 0 0 3 3 3 2 Flagellar regulatory protein FleQ PAS_3 PF08447.12 GAM25884.1 - 0.0018 18.5 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold Cons_hypoth95 PF03602.15 GAM25884.1 - 0.014 15.0 0.1 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Creatinase_N_2 PF16189.5 GAM25885.1 - 2.2e-52 177.4 1.2 7.8e-51 172.4 0.0 2.7 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 GAM25885.1 - 3.8e-38 131.3 0.0 5.6e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 GAM25885.1 - 1.2e-24 87.4 0.0 4.5e-19 69.4 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 GAM25885.1 - 1.3e-20 73.2 0.3 5.4e-20 71.2 0.1 2.3 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Ras PF00071.22 GAM25886.1 - 2.1e-53 180.3 0.6 2.6e-53 180.0 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM25886.1 - 5.3e-25 88.0 0.1 9.4e-25 87.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM25886.1 - 1.1e-09 38.0 0.2 1.5e-09 37.6 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM25886.1 - 0.0017 17.9 0.2 0.0036 16.9 0.2 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Cmc1 PF08583.10 GAM25887.1 - 2.6e-05 24.2 3.9 0.0038 17.2 0.1 2.4 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 GAM25887.1 - 0.00025 21.3 2.9 0.00049 20.3 2.9 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Colipase-like PF15083.6 GAM25887.1 - 0.016 15.3 2.2 0.024 14.7 2.2 1.3 1 0 0 1 1 1 0 Colipase-like CHCH PF06747.13 GAM25887.1 - 0.28 11.4 13.6 2.7 8.2 1.4 3.8 3 1 0 3 3 3 0 CHCH domain DUF3128 PF11326.8 GAM25887.1 - 0.35 11.3 6.2 1.2 9.6 0.3 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3128) UCR_hinge PF02320.16 GAM25887.1 - 0.88 9.8 8.8 8 6.7 2.0 3.0 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein CX9C PF16860.5 GAM25887.1 - 3.6 7.7 10.1 6.5 6.9 0.1 3.4 3 1 1 4 4 4 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cellulase PF00150.18 GAM25888.1 - 5.1e-18 65.5 0.6 1.2e-17 64.3 0.6 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) COG5 PF10392.9 GAM25889.1 - 1.1e-26 93.5 4.5 1.1e-26 93.5 4.5 3.5 3 1 1 4 4 4 1 Golgi transport complex subunit 5 COG2 PF06148.11 GAM25889.1 - 6.1e-10 39.3 3.5 6.1e-10 39.3 3.5 3.5 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 GAM25889.1 - 3e-05 24.0 2.7 3e-05 24.0 2.7 3.4 3 0 0 3 3 3 1 Vps51/Vps67 DUF724 PF05266.14 GAM25889.1 - 0.18 11.6 2.8 0.53 10.1 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) COG4 PF08318.12 GAM25890.1 - 4.7e-45 154.1 12.5 7.7e-45 153.4 11.8 1.7 1 1 1 2 2 2 1 COG4 transport protein malic PF00390.19 GAM25890.1 - 0.2 11.5 1.4 4.4 7.1 0.2 2.6 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain DUF1664 PF07889.12 GAM25890.1 - 5.3 7.1 9.8 18 5.4 0.3 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Acetyltransf_3 PF13302.7 GAM25892.1 - 3.1e-19 70.0 0.0 3.9e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAM25892.1 - 1.8e-07 30.9 0.1 5.4e-07 29.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM25892.1 - 5.9e-07 29.7 0.1 9.3e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 GAM25892.1 - 1.4e-05 25.2 0.1 2.9e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM25892.1 - 2.7e-05 24.0 0.0 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAM25892.1 - 0.004 17.1 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Transthyretin PF00576.21 GAM25893.1 - 2.8e-37 127.8 0.5 3.3e-37 127.6 0.5 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF4493 PF14900.6 GAM25893.1 - 0.0041 17.0 0.2 0.0048 16.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4493) SdrD_B PF17210.3 GAM25893.1 - 0.0064 16.7 0.2 0.011 16.0 0.2 1.4 1 0 0 1 1 1 1 SdrD B-like domain bMG3 PF11974.8 GAM25893.1 - 0.02 14.9 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain EMP24_GP25L PF01105.24 GAM25893.1 - 0.051 13.5 0.0 0.06 13.3 0.0 1.0 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF5121 PF17165.4 GAM25893.1 - 0.15 12.5 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5121) FbpA PF05833.11 GAM25895.1 - 1.8e-38 132.5 17.6 1.8e-38 132.5 17.6 3.5 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 GAM25895.1 - 4.3e-35 120.7 0.1 2e-34 118.5 0.1 2.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 GAM25895.1 - 2.3e-25 88.6 0.1 2.3e-25 88.6 0.1 5.1 2 1 4 6 6 6 1 NFACT protein C-terminal domain DUF5590 PF17881.1 GAM25895.1 - 0.04 14.0 4.9 1.1 9.4 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5590) LRR_4 PF12799.7 GAM25896.1 - 4.1e-26 90.6 44.9 5.9e-06 26.5 0.2 7.8 4 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM25896.1 - 6.1e-23 80.4 46.5 1.7e-06 27.7 1.6 7.1 1 1 5 7 7 7 7 Leucine rich repeat LRR_1 PF00560.33 GAM25896.1 - 2.1e-11 42.7 34.8 1.1 10.1 0.4 10.6 9 1 0 9 9 9 5 Leucine Rich Repeat LRR_6 PF13516.6 GAM25896.1 - 1.4e-07 31.0 51.3 0.15 12.2 0.2 10.7 11 0 0 11 11 11 7 Leucine Rich repeat LRR_9 PF14580.6 GAM25896.1 - 0.004 16.7 12.7 0.13 11.8 0.4 4.1 1 1 4 5 5 5 4 Leucine-rich repeat Filamin PF00630.19 GAM25896.1 - 0.2 12.5 0.0 0.38 11.6 0.0 1.4 1 0 0 1 1 1 0 Filamin/ABP280 repeat zinc_ribbon_10 PF10058.9 GAM25897.1 - 1.2e-17 63.3 0.5 2.2e-17 62.5 0.5 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Wzy_C PF04932.15 GAM25897.1 - 0.055 13.1 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase Neur_chan_memb PF02932.16 GAM25897.1 - 5.5 7.0 10.0 1.1 9.2 2.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ubiquitin PF00240.23 GAM25898.1 - 2.1e-08 33.8 0.1 2.1e-08 33.8 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 GAM25898.1 - 1.5e-05 25.5 0.1 1.5e-05 25.5 0.1 2.4 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAM25898.1 - 0.003 17.6 2.2 0.0038 17.3 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 GAM25898.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Presenilin PF01080.17 GAM25898.1 - 0.25 10.1 3.2 0.15 10.8 0.1 1.9 2 0 0 2 2 2 0 Presenilin RP-C_C PF11800.8 GAM25898.1 - 6.1 6.9 10.3 0.77 9.8 3.5 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region CPSF100_C PF13299.6 GAM25898.1 - 7.3 6.7 6.2 1.1 9.4 0.7 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Coilin_N PF15862.5 GAM25898.1 - 8.4 6.2 8.2 52 3.6 5.9 2.4 2 1 0 2 2 2 0 Coilin N-terminus WD40 PF00400.32 GAM25899.1 - 1.3e-08 35.3 6.4 0.2 12.6 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DNA_pol_phi PF04931.13 GAM25899.1 - 0.32 9.0 10.4 0.48 8.5 10.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Complex1_LYR PF05347.15 GAM25900.1 - 0.0096 15.9 0.9 0.012 15.7 0.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAM25900.1 - 0.057 14.2 0.2 0.062 14.0 0.2 1.1 1 0 0 1 1 1 0 Complex1_LYR-like MIP PF00230.20 GAM25901.1 - 7.8e-31 107.5 13.3 9.5e-31 107.3 13.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2238 PF09997.9 GAM25901.1 - 0.25 11.1 4.2 0.094 12.5 1.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) G-alpha PF00503.20 GAM25902.1 - 9e-115 383.6 4.1 1.1e-114 383.3 4.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM25902.1 - 3.6e-12 46.1 0.5 3.2e-08 33.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 GAM25902.1 - 0.011 16.0 0.7 2.1 8.6 0.1 2.8 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Tipalpha PF16753.5 GAM25902.1 - 0.012 15.5 0.9 0.018 14.8 0.1 1.8 2 0 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter Gtr1_RagA PF04670.12 GAM25902.1 - 0.014 14.8 1.1 3 7.1 0.1 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TniB PF05621.11 GAM25902.1 - 0.1 12.0 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 GAM25902.1 - 0.13 11.8 0.3 1.5 8.3 0.1 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CBS PF00571.28 GAM25903.1 - 2.6e-24 85.4 2.4 4.4e-13 49.5 0.5 3.0 3 0 0 3 3 3 2 CBS domain DisA_N PF02457.16 GAM25903.1 - 0.014 15.0 0.1 0.027 14.1 0.1 1.7 1 1 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding HisK_sensor PF18698.1 GAM25903.1 - 0.053 13.9 0.2 0.083 13.3 0.2 1.3 1 0 0 1 1 1 0 Histidine kinase sensor domain Delta_lysin PF05372.11 GAM25903.1 - 0.1 11.9 1.0 0.27 10.5 1.0 1.7 1 0 0 1 1 1 0 Delta lysin family CENP-U PF13097.6 GAM25904.1 - 0.11 12.4 4.4 0.16 11.9 4.4 1.3 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Macoilin PF09726.9 GAM25905.1 - 0.18 10.3 24.1 0.21 10.1 24.1 1.0 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 GAM25905.1 - 1.4 6.9 20.6 1.7 6.6 20.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CRT10 PF08728.10 GAM25905.1 - 7.6 4.6 12.8 8.5 4.4 12.8 1.1 1 0 0 1 1 1 0 CRT10 DUF3402 PF11882.8 GAM25906.1 - 3.9e-60 204.3 12.1 1.2e-35 123.5 2.2 3.2 2 1 1 3 3 3 3 Domain of unknown function (DUF3402) N1221 PF07923.13 GAM25906.1 - 8.6e-26 90.8 0.8 1.7e-25 89.8 0.1 1.8 2 0 0 2 2 2 1 N1221-like protein DUF4304 PF14137.6 GAM25906.1 - 0.099 12.8 0.1 0.41 10.8 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) DUF3800 PF12686.7 GAM25906.1 - 0.16 12.6 2.3 0.3 11.7 0.1 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) Frag1 PF10277.9 GAM25907.1 - 2.1e-45 154.9 14.6 2.4e-45 154.8 14.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Ribosomal_L11 PF00298.19 GAM25908.1 - 9e-17 61.4 0.5 9e-17 61.4 0.5 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 GAM25908.1 - 9.5e-15 54.2 0.2 1.6e-14 53.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain AT_hook PF02178.19 GAM25909.1 - 0.016 15.0 44.7 0.57 10.2 5.4 4.6 4 0 0 4 4 4 0 AT hook motif Hemerythrin PF01814.23 GAM25910.1 - 1.2e-07 32.5 0.0 1.8e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PhaP_Bmeg PF09602.10 GAM25910.1 - 0.0004 20.4 0.4 0.00091 19.2 0.4 1.7 1 1 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Mating_N PF12731.7 GAM25910.1 - 0.019 15.1 0.0 0.068 13.3 0.0 1.9 2 0 0 2 2 2 0 Mating-type protein beta 1 Erp_C PF06780.11 GAM25910.1 - 0.023 14.7 0.1 2.9 7.9 0.0 2.2 1 1 1 2 2 2 0 Erp protein C-terminus PdaC PF13739.6 GAM25910.1 - 0.11 13.4 3.3 6.4 7.8 0.3 2.3 2 0 0 2 2 2 0 Deacetylase PdaC Sod_Cu PF00080.20 GAM25911.1 - 7.3e-27 94.3 5.6 4.7e-25 88.4 0.4 2.5 3 0 0 3 3 3 2 Copper/zinc superoxide dismutase (SODC) PYC_OADA PF02436.18 GAM25911.1 - 0.062 13.0 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Conserved carboxylase domain DUF2834 PF11196.8 GAM25911.1 - 0.22 11.9 3.4 0.23 11.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) FSA_C PF10479.9 GAM25911.1 - 4 5.4 16.5 8 4.5 16.5 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sod_Cu PF00080.20 GAM25912.1 - 1.1e-28 100.2 1.1 2.9e-24 85.8 0.2 2.2 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) SET PF00856.28 GAM25914.1 - 1e-09 39.0 0.1 2.1e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 SET domain Sec15 PF04091.12 GAM25914.1 - 0.021 14.3 0.2 0.034 13.6 0.2 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF3446 PF11928.8 GAM25914.1 - 0.35 11.2 15.7 0.57 10.5 0.9 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Glyco_hydro_47 PF01532.20 GAM25915.1 - 1.3e-112 377.1 0.0 1.8e-112 376.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FNIP PF05725.12 GAM25916.1 - 5.3e-35 119.3 23.7 4.7e-13 49.1 0.0 7.0 5 2 1 6 6 6 6 FNIP Repeat LRR_8 PF13855.6 GAM25916.1 - 0.64 9.8 4.9 0.37 10.6 0.5 2.6 2 0 0 2 2 2 0 Leucine rich repeat Ank_2 PF12796.7 GAM25917.1 - 1.4e-08 35.2 6.4 0.045 14.4 0.1 5.3 5 2 2 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM25917.1 - 1.8e-05 25.2 8.4 1.2 9.8 0.0 5.2 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM25917.1 - 7.5e-05 22.8 4.5 16 6.4 0.0 7.8 9 0 0 9 9 9 1 Ankyrin repeat NOP19 PF10863.8 GAM25917.1 - 8e-05 22.5 5.7 0.00014 21.7 5.7 1.3 1 0 0 1 1 1 1 Nucleolar protein 19 DUF1477 PF07346.11 GAM25917.1 - 0.001 19.3 0.7 0.049 13.9 0.0 3.8 3 2 1 4 4 4 1 Protein of unknown function (DUF1477) FNIP PF05725.12 GAM25918.1 - 1e-70 233.7 28.0 6.2e-13 48.7 2.0 8.2 3 3 5 8 8 8 8 FNIP Repeat LRR_5 PF13306.6 GAM25918.1 - 5.6e-12 45.7 1.1 0.00036 20.5 0.3 3.2 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) ParBc_2 PF08857.11 GAM25918.1 - 0.0014 18.8 0.1 79 3.3 0.0 5.5 4 2 1 6 6 6 0 Putative ParB-like nuclease DUF4907 PF16250.5 GAM25918.1 - 0.1 12.5 0.4 19 5.2 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4907) FNIP PF05725.12 GAM25919.1 - 4.9e-78 257.1 38.0 1.3e-11 44.4 0.2 10.3 7 2 4 11 11 11 11 FNIP Repeat DUF1769 PF08588.10 GAM25919.1 - 0.00028 21.0 3.8 1.8 8.9 0.1 5.3 3 1 2 5 5 5 2 Protein of unknown function (DUF1769) Complex1_LYR PF05347.15 GAM25921.1 - 0.00011 22.2 0.1 0.00017 21.6 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zf-UBR PF02207.20 GAM25922.1 - 2.2e-18 66.2 13.1 2.2e-18 66.2 13.1 3.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 GAM25922.1 - 6.1e-09 35.5 0.2 1.4e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 GAM25922.1 - 0.012 15.9 3.3 0.012 15.9 3.3 4.2 4 0 0 4 4 4 0 Ring finger domain G-patch_2 PF12656.7 GAM25922.1 - 0.044 13.9 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 G-patch domain CwfJ_C_1 PF04677.15 GAM25923.1 - 2.7e-26 91.8 0.4 5.6e-26 90.8 0.4 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 GAM25923.1 - 4.6e-08 33.9 0.8 4.6e-08 33.9 0.8 2.5 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 Pex14_N PF04695.13 GAM25923.1 - 0.69 10.6 11.3 0.16 12.6 0.6 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3408 PF11888.8 GAM25923.1 - 4.3 7.5 7.8 6.3 6.9 1.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3408) Trm5_N PF18093.1 GAM25924.1 - 0.14 12.1 0.2 21 5.1 0.0 2.4 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain CDC4_D PF16856.5 GAM25924.1 - 7.4 6.5 7.5 0.3 11.0 0.4 2.3 3 0 0 3 3 3 0 Cell division control protein 4 dimerisation domain VWA PF00092.28 GAM25925.1 - 9.3e-09 35.8 0.4 1.6e-08 35.0 0.1 1.5 2 0 0 2 2 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM25925.1 - 3.8e-08 33.9 0.3 9.5e-08 32.7 0.1 1.8 2 0 0 2 2 1 1 von Willebrand factor type A domain IIGP PF05049.13 GAM25925.1 - 0.0015 17.7 0.2 1.2 8.1 0.0 2.4 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) DUF815 PF05673.13 GAM25925.1 - 0.0028 16.9 0.0 0.0064 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 GAM25925.1 - 0.0035 17.2 0.0 0.048 13.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ATPase_2 PF01637.18 GAM25925.1 - 0.0062 16.5 0.6 0.027 14.4 0.0 2.2 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea DZR PF12773.7 GAM25925.1 - 0.0065 16.5 8.9 0.0065 16.5 8.9 2.9 1 1 1 2 2 2 1 Double zinc ribbon AAA_29 PF13555.6 GAM25925.1 - 0.0066 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain VWA_CoxE PF05762.14 GAM25925.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein MMR_HSR1 PF01926.23 GAM25925.1 - 0.014 15.4 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 GAM25925.1 - 0.021 14.2 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family vWA-TerF-like PF10138.9 GAM25925.1 - 0.023 14.8 0.1 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 vWA found in TerF C terminus AAA_7 PF12775.7 GAM25925.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GAM25925.1 - 0.038 14.4 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 GAM25925.1 - 0.041 14.4 0.0 0.09 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 GAM25925.1 - 0.083 12.9 0.9 1.3 9.1 0.1 2.6 3 0 0 3 3 3 0 Dynamin family SMC_N PF02463.19 GAM25925.1 - 0.11 12.0 0.2 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAM25925.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 GAM25925.1 - 0.19 11.0 0.0 0.42 9.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 GAM25927.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ABC1 PF03109.16 GAM25928.1 - 2.7e-31 108.2 0.1 4.6e-31 107.4 0.1 1.4 1 0 0 1 1 1 1 ABC1 family ApoC-I PF04691.12 GAM25928.1 - 0.02 14.8 0.1 0.053 13.5 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) PhnA_Zn_Ribbon PF08274.12 GAM25929.1 - 0.0095 15.9 7.8 0.12 12.4 3.6 2.4 2 0 0 2 2 2 2 PhnA Zinc-Ribbon DUF2318 PF10080.9 GAM25929.1 - 0.015 15.4 3.4 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) ADK_lid PF05191.14 GAM25929.1 - 1.7 8.7 9.0 3.2 7.8 0.1 3.9 3 1 1 4 4 4 0 Adenylate kinase, active site lid Rpr2 PF04032.16 GAM25929.1 - 2 8.7 18.8 0.38 11.1 0.6 4.1 3 1 1 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain FYVE PF01363.21 GAM25929.1 - 3.7 7.8 14.8 37 4.6 2.1 2.5 1 1 1 2 2 2 0 FYVE zinc finger Spt20 PF12090.8 GAM25929.1 - 3.8 7.1 25.2 1.1 8.8 16.5 2.5 2 0 0 2 2 2 0 Spt20 family DUF641 PF04859.12 GAM25930.1 - 0.0086 16.4 4.6 0.0086 16.4 4.6 6.1 2 1 3 5 5 5 1 Plant protein of unknown function (DUF641) Rab_bind PF16704.5 GAM25930.1 - 0.012 15.6 5.1 0.014 15.4 1.9 2.7 2 0 0 2 2 2 0 Rab binding domain GRIP PF01465.20 GAM25930.1 - 0.013 15.4 1.4 0.027 14.4 0.0 2.4 3 0 0 3 3 3 0 GRIP domain FUSC PF04632.12 GAM25930.1 - 2.9 6.3 4.4 1.8 7.0 0.0 2.5 3 1 1 4 4 4 0 Fusaric acid resistance protein family P5CR_dimer PF14748.6 GAM25931.1 - 9.6e-26 90.0 1.4 1.7e-25 89.2 1.4 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAM25931.1 - 4.9e-16 59.1 0.1 1.3e-15 57.7 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 GAM25931.1 - 0.0015 18.1 0.4 0.012 15.3 0.4 2.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 GAM25931.1 - 0.0038 16.8 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 GAM25931.1 - 0.0041 17.1 0.7 0.017 15.1 0.7 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 GAM25931.1 - 0.0048 17.1 0.0 0.0093 16.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 GAM25931.1 - 0.0081 16.4 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 GAM25931.1 - 0.027 13.9 0.0 0.069 12.5 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAM25931.1 - 0.029 14.6 0.0 0.059 13.6 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 GAM25931.1 - 0.074 12.9 0.0 0.25 11.2 0.0 2.0 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FNIP PF05725.12 GAM25932.1 - 1.7e-80 264.9 19.9 7.7e-13 48.4 0.1 8.4 4 3 6 10 10 10 9 FNIP Repeat zf-RING_2 PF13639.6 GAM25933.1 - 2.8e-12 46.8 14.1 2.8e-12 46.8 14.1 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 GAM25933.1 - 2.4e-09 36.8 7.7 5.4e-09 35.6 7.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAM25933.1 - 9.1e-07 29.1 10.3 3e-06 27.4 10.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAM25933.1 - 1.4e-06 28.1 9.2 4e-06 26.6 9.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM25933.1 - 7.8e-06 25.7 8.8 7.8e-06 25.7 8.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM25933.1 - 1.5e-05 24.9 7.5 1.5e-05 24.9 7.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain SSP160 PF06933.11 GAM25933.1 - 3.1e-05 22.4 9.1 3.1e-05 22.4 9.1 2.1 3 0 0 3 3 3 1 Special lobe-specific silk protein SSP160 Prok-RING_4 PF14447.6 GAM25933.1 - 7.6e-05 22.5 8.8 0.00022 21.0 8.8 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAM25933.1 - 0.00014 21.8 4.5 0.00039 20.4 4.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAM25933.1 - 0.00092 19.0 10.5 0.00092 19.0 10.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Mucin PF01456.17 GAM25933.1 - 0.0026 17.8 14.3 0.0026 17.8 14.3 2.9 3 0 0 3 3 3 1 Mucin-like glycoprotein DUF3439 PF11921.8 GAM25933.1 - 0.0096 15.9 10.8 0.0096 15.9 10.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) zf-ANAPC11 PF12861.7 GAM25933.1 - 0.011 15.7 5.4 0.03 14.4 5.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FSA_C PF10479.9 GAM25933.1 - 0.13 10.3 6.9 0.2 9.7 6.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Macoilin PF09726.9 GAM25933.1 - 0.3 9.6 12.8 0.44 9.1 12.8 1.1 1 0 0 1 1 1 0 Macoilin family GEMIN8 PF15348.6 GAM25933.1 - 0.38 11.0 0.0 0.38 11.0 0.0 2.4 2 1 1 3 3 2 0 Gemini of Cajal bodies-associated protein 8 SCIMP PF15050.6 GAM25933.1 - 0.54 10.7 3.0 1.1 9.7 0.1 2.8 3 0 0 3 3 3 0 SCIMP protein AJAP1_PANP_C PF15298.6 GAM25933.1 - 0.58 10.3 16.2 0.19 11.9 12.9 1.9 2 0 0 2 2 1 0 AJAP1/PANP C-terminus CSRNP_N PF16019.5 GAM25933.1 - 0.87 9.5 6.9 0.35 10.8 1.3 2.4 1 1 1 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus FANCL_C PF11793.8 GAM25933.1 - 1 9.6 10.3 16 5.8 10.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3533 PF12051.8 GAM25933.1 - 1.6 7.6 14.5 0.024 13.6 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) HEAT PF02985.22 GAM25934.1 - 7e-47 153.4 18.8 0.001 19.1 0.0 13.9 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 GAM25934.1 - 1.6e-41 140.6 0.1 4.1e-10 39.9 0.0 7.1 3 1 4 7 7 7 7 HEAT repeats HEAT_EZ PF13513.6 GAM25934.1 - 3.9e-11 43.2 7.4 0.041 14.4 0.0 8.2 6 2 2 8 8 8 2 HEAT-like repeat Cnd1 PF12717.7 GAM25934.1 - 2.4e-10 40.7 7.2 0.019 15.0 0.0 5.3 4 1 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GAM25934.1 - 3.2e-10 40.5 2.0 0.28 11.8 0.0 6.9 4 1 4 8 8 8 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 GAM25934.1 - 1.5e-09 37.0 7.9 0.021 13.4 0.6 4.1 2 1 2 4 4 4 4 Adaptin N terminal region Granulin PF00396.18 GAM25934.1 - 4.2e-09 36.6 22.5 4.2e-09 36.6 22.5 2.3 2 0 0 2 2 2 1 Granulin Arm PF00514.23 GAM25934.1 - 7.3e-09 35.4 0.4 0.12 12.5 0.0 6.6 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 GAM25934.1 - 2.3e-08 33.9 2.1 0.00038 20.1 0.0 5.3 2 1 2 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 GAM25934.1 - 1.5e-05 25.1 3.5 0.69 10.1 0.1 4.6 3 2 1 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 GAM25934.1 - 0.0022 17.2 1.9 0.08 12.0 0.1 4.0 2 2 1 4 4 4 1 Interferon-related developmental regulator (IFRD) API5 PF05918.11 GAM25934.1 - 0.013 14.3 6.9 0.36 9.6 0.2 3.9 4 1 1 5 5 5 0 Apoptosis inhibitory protein 5 (API5) Tti2 PF10521.9 GAM25934.1 - 0.26 10.8 4.2 26 4.2 0.0 4.1 4 0 0 4 4 4 0 Tti2 family CDC50 PF03381.15 GAM25935.1 - 1.7e-81 273.9 0.0 3e-81 273.0 0.0 1.4 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3953 PF13129.6 GAM25935.1 - 6 6.7 6.6 1.9 8.3 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) Ras PF00071.22 GAM25936.1 - 2e-28 99.0 0.0 4.3e-23 81.7 0.0 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 GAM25936.1 - 1.7e-13 50.9 0.1 4.2e-13 49.6 0.0 1.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM25936.1 - 1.6e-05 24.4 0.0 3.9e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM25936.1 - 0.013 15.6 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Sec3_C PF09763.9 GAM25936.1 - 0.085 11.2 7.4 0.094 11.1 7.4 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF908 PF06012.12 GAM25936.1 - 0.1 12.0 7.3 0.11 11.9 7.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) ANAPC1 PF12859.7 GAM25936.1 - 0.36 11.4 7.3 0.51 10.9 7.3 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 PAP1 PF08601.10 GAM25936.1 - 0.38 10.4 17.6 0.48 10.1 17.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SSP160 PF06933.11 GAM25936.1 - 0.62 8.2 20.4 0.76 7.9 20.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4834 PF16118.5 GAM25936.1 - 1.2 10.2 4.8 1.7 9.7 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SCHIP-1 PF10148.9 GAM25936.1 - 1.4 8.5 5.7 1.7 8.2 5.7 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Macoilin PF09726.9 GAM25936.1 - 1.5 7.3 15.6 1.6 7.2 15.6 1.0 1 0 0 1 1 1 0 Macoilin family Bul1_C PF04426.12 GAM25936.1 - 4.1 6.7 10.5 5.5 6.3 10.5 1.1 1 0 0 1 1 1 0 Bul1 C terminus Apt1 PF10351.9 GAM25936.1 - 6.5 5.5 17.7 7.4 5.3 17.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 GAM25936.1 - 8.6 5.0 8.7 10 4.8 8.7 1.1 1 0 0 1 1 1 0 Presenilin MATH PF00917.26 GAM25937.1 - 5e-41 139.4 16.1 2.2e-14 53.6 1.5 4.5 4 0 0 4 4 4 4 MATH domain USP7_ICP0_bdg PF12436.8 GAM25937.1 - 3e-34 118.4 0.1 3e-34 118.4 0.1 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 Ubiquitin_2 PF14560.6 GAM25937.1 - 0.056 13.9 0.3 3.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-like domain Mitofilin PF09731.9 GAM25937.1 - 0.53 9.1 10.3 0.76 8.6 10.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3295 PF11702.8 GAM25937.1 - 1.9 7.7 16.9 3.2 7.0 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) TFIIA PF03153.13 GAM25937.1 - 4.3 7.2 29.3 7.1 6.5 29.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF908 PF06012.12 GAM25937.1 - 5 6.4 15.7 2.2 7.6 10.9 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) SUIM_assoc PF16619.5 GAM25938.1 - 2.5 8.2 13.9 3.4 7.8 13.9 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 GAM25939.1 - 6.8e-19 67.9 0.6 8.5e-06 26.4 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM25939.1 - 1.1e-06 28.8 0.2 0.13 12.5 0.0 4.3 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM25939.1 - 0.0087 15.1 0.0 0.29 10.0 0.0 2.9 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAM25939.1 - 0.012 14.3 0.1 1.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 CDC45 PF02724.14 GAM25939.1 - 0.11 10.8 13.2 0.0061 14.9 2.4 2.1 2 0 0 2 2 2 0 CDC45-like protein Ndc1_Nup PF09531.10 GAM25939.1 - 0.27 9.9 3.8 0.41 9.3 3.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PP28 PF10252.9 GAM25940.1 - 5.6e-13 49.1 15.9 5.6e-13 49.1 15.9 2.5 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 Nop53 PF07767.11 GAM25940.1 - 0.038 13.4 27.4 0.047 13.1 27.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SOBP PF15279.6 GAM25940.1 - 6.2 7.3 8.3 7.7 7.0 8.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein ACPS PF01648.20 GAM25941.1 - 0.001 19.2 1.1 0.0013 18.9 1.1 1.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily NDUF_B7 PF05676.13 GAM25941.1 - 0.0062 16.2 4.8 0.012 15.4 4.8 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 GAM25941.1 - 0.028 14.6 3.3 4.5 7.5 0.2 2.6 2 0 0 2 2 2 0 CHCH domain Cmc1 PF08583.10 GAM25941.1 - 0.048 13.7 5.3 0.082 12.9 5.3 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Y_phosphatase PF00102.27 GAM25942.1 - 3.5e-71 239.5 2.4 1.7e-35 122.7 0.9 2.2 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 GAM25942.1 - 1.1e-05 25.3 0.1 3.2e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAM25942.1 - 3.1e-05 24.1 0.1 5.3e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 GAM25942.1 - 0.00016 21.7 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF4611 PF15387.6 GAM25942.1 - 0.077 13.2 5.9 0.53 10.5 6.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 GAM25942.1 - 0.24 10.7 9.3 3.6 6.8 10.3 2.0 2 0 0 2 2 2 0 NOA36 protein DUF2076 PF09849.9 GAM25942.1 - 1.5 8.8 7.9 2.4 8.2 7.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Kelch_6 PF13964.6 GAM25943.1 - 2e-08 34.2 3.2 0.037 14.3 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 GAM25943.1 - 8.6e-08 31.6 2.5 0.00025 20.6 0.1 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM25943.1 - 2e-06 27.7 1.0 0.0022 17.9 0.1 3.7 3 1 0 3 3 3 2 Galactose oxidase, central domain Fib_alpha PF08702.10 GAM25943.1 - 0.0073 16.5 0.3 0.015 15.5 0.3 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Kelch_2 PF07646.15 GAM25943.1 - 0.035 14.1 0.8 10 6.3 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.6 GAM25943.1 - 0.12 12.4 3.5 1.2 9.2 0.0 3.2 3 0 0 3 3 3 0 Kelch motif IPPT PF01715.17 GAM25944.1 - 2e-52 178.3 0.1 3.5e-52 177.5 0.1 1.4 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 GAM25944.1 - 7e-07 28.9 0.3 3.3e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Isopentenyl transferase Hpr_kinase_C PF07475.12 GAM25944.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain DPPIV_rep PF18811.1 GAM25944.1 - 1.4 9.0 5.4 2 8.4 1.0 2.7 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) low complexity region HSBP1 PF06825.12 GAM25945.1 - 2.3e-18 65.8 2.7 3e-18 65.4 2.7 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 IL11 PF07400.11 GAM25945.1 - 0.004 16.8 0.3 0.0044 16.7 0.3 1.1 1 0 0 1 1 1 1 Interleukin 11 YvrJ PF12841.7 GAM25945.1 - 0.13 11.8 0.1 0.63 9.6 0.1 2.0 1 1 0 1 1 1 0 YvrJ protein family BCNT PF07572.12 GAM25946.1 - 1.6e-16 60.1 1.9 1.6e-16 60.1 1.9 3.1 2 1 0 3 3 3 1 Bucentaur or craniofacial development UPA_2 PF17809.1 GAM25946.1 - 0.021 14.6 0.4 0.041 13.7 0.4 1.4 1 0 0 1 1 1 0 UPA domain FAM220 PF15487.6 GAM25946.1 - 1.2 8.7 14.3 2.1 7.9 14.3 1.3 1 0 0 1 1 1 0 FAM220 family MIF4G_like_2 PF09090.11 GAM25946.1 - 1.2 8.5 12.7 2.2 7.7 12.7 1.4 1 0 0 1 1 1 0 MIF4G like Methyltransf_31 PF13847.6 GAM25947.1 - 1.3e-10 41.3 0.0 2.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM25947.1 - 3e-10 40.7 0.0 5.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM25947.1 - 6.9e-07 29.9 0.0 1.8e-06 28.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM25947.1 - 6.5e-06 26.7 0.0 1.4e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM25947.1 - 5.6e-05 23.0 0.0 7.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 GAM25947.1 - 0.0038 16.9 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 GAM25947.1 - 0.0099 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB ADH_zinc_N PF00107.26 GAM25947.1 - 0.013 15.4 0.0 0.038 14.0 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase tRNA_U5-meth_tr PF05958.11 GAM25947.1 - 0.022 13.8 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF43 PF01861.16 GAM25947.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain RNA_pol_Rbc25 PF08292.12 GAM25948.1 - 3.1e-33 114.7 0.3 3.1e-33 114.7 0.3 2.2 3 0 0 3 3 3 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 GAM25948.1 - 3.5e-11 43.3 0.0 6.9e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 GAM25948.1 - 0.35 11.2 2.8 1.6 9.1 0.0 3.1 4 0 0 4 4 4 0 S1 RNA binding domain PUF PF00806.19 GAM25949.1 - 5.3e-37 123.4 20.9 3.5e-06 26.4 0.4 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 GAM25949.1 - 5.9e-06 26.7 3.1 0.01 16.2 0.8 4.0 1 1 2 4 4 4 3 CPL (NUC119) domain DUF445 PF04286.12 GAM25949.1 - 0.0021 17.9 2.9 0.0021 17.9 2.9 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF445) ATP-grasp_2 PF08442.10 GAM25950.1 - 4.2e-74 248.5 0.3 8e-74 247.6 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 GAM25950.1 - 5e-27 94.6 1.2 8.9e-27 93.8 1.2 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 GAM25950.1 - 3.8e-09 36.3 0.0 6.7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAM25950.1 - 6.3e-05 22.8 0.7 0.0016 18.3 0.0 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 GAM25950.1 - 0.0071 16.1 0.1 0.02 14.7 0.1 1.8 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain RasGEF PF00617.19 GAM25951.1 - 7.4e-52 176.1 1.1 7.4e-52 176.1 1.1 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM25951.1 - 1.3e-16 60.7 1.9 5.1e-16 58.8 1.9 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif Mad3_BUB1_I PF08311.12 GAM25951.1 - 0.075 13.0 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Ribosomal_S7 PF00177.21 GAM25951.1 - 0.16 11.6 0.5 1.2 8.8 0.2 2.4 3 0 0 3 3 3 0 Ribosomal protein S7p/S5e FAM199X PF15814.5 GAM25952.1 - 0.28 10.2 3.2 0.3 10.1 3.2 1.0 1 0 0 1 1 1 0 Protein family FAM199X tRNA-synt_His PF13393.6 GAM25953.1 - 4.8e-48 164.0 0.0 6.1e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 GAM25953.1 - 2.4e-14 53.2 0.2 5.5e-14 52.1 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 GAM25953.1 - 8.9e-05 22.1 0.6 0.00016 21.3 0.6 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 GAM25953.1 - 0.00015 20.9 0.0 0.0011 18.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Pkinase_Tyr PF07714.17 GAM25955.1 - 5.3e-53 179.9 0.0 8.7e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM25955.1 - 3.5e-51 174.1 0.1 1.2e-50 172.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Ank_2 PF12796.7 GAM25955.1 - 5.7e-24 84.5 2.3 2e-08 34.7 0.4 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAM25955.1 - 1.4e-23 82.3 0.6 2.5e-05 24.5 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 GAM25955.1 - 1.6e-23 82.7 0.4 3.6e-08 33.8 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM25955.1 - 1e-20 71.6 1.8 0.016 15.7 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat GRAM PF02893.20 GAM25955.1 - 1e-19 70.5 0.2 2.1e-19 69.5 0.2 1.5 1 0 0 1 1 1 1 GRAM domain Ank_5 PF13857.6 GAM25955.1 - 8.3e-18 64.2 3.1 6.7e-05 23.1 0.3 5.6 2 2 3 5 5 5 3 Ankyrin repeats (many copies) C1_1 PF00130.22 GAM25955.1 - 1.4e-11 44.1 4.5 3.1e-11 43.0 4.5 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 GAM25955.1 - 0.0035 17.2 3.7 0.01 15.7 3.7 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PIP49_C PF12260.8 GAM25955.1 - 0.042 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 PH PF00169.29 GAM25955.1 - 0.048 14.2 0.0 0.19 12.2 0.0 2.0 1 0 0 1 1 1 0 PH domain Pkinase_fungal PF17667.1 GAM25955.1 - 0.11 11.3 1.1 0.14 10.9 0.0 1.7 2 0 0 2 2 1 0 Fungal protein kinase SAM_2 PF07647.17 GAM25955.1 - 0.11 12.6 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2318 PF10080.9 GAM25955.1 - 0.14 12.3 0.9 0.45 10.7 0.9 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) APH PF01636.23 GAM25955.1 - 0.22 11.4 0.1 2.5 7.9 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family PHD PF00628.29 GAM25955.1 - 0.68 9.9 2.9 2.2 8.3 2.9 1.9 1 0 0 1 1 1 0 PHD-finger REPA_OB_2 PF16900.5 GAM25956.1 - 2.8e-19 68.9 0.2 2.6e-16 59.3 0.1 3.0 2 0 0 2 2 2 2 Replication protein A OB domain Rep_fac-A_C PF08646.10 GAM25956.1 - 6.4e-10 38.9 0.5 6.4e-10 38.9 0.5 3.4 4 0 0 4 4 4 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.25 GAM25956.1 - 2.8e-05 24.0 0.1 0.0081 16.1 0.0 3.3 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 GAM25956.1 - 0.01 16.1 0.0 0.038 14.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF223 POT1 PF02765.17 GAM25956.1 - 0.015 15.2 0.1 0.015 15.2 0.1 2.3 3 0 0 3 3 3 0 Telomeric single stranded DNA binding POT1/CDC13 DUF629 PF04780.12 GAM25956.1 - 0.019 13.5 0.1 0.019 13.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF629) RecJ_OB PF17768.1 GAM25956.1 - 0.03 14.6 0.1 0.54 10.5 0.0 2.7 2 0 0 2 2 2 0 RecJ OB domain TFIIS_C PF01096.18 GAM25956.1 - 0.2 11.6 2.5 0.44 10.4 0.3 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Spt20 PF12090.8 GAM25956.1 - 0.25 10.9 12.8 0.55 9.8 12.8 1.5 1 0 0 1 1 1 0 Spt20 family WH1 PF00568.23 GAM25957.1 - 3.4e-19 68.8 0.0 5e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 GAM25957.1 - 2.8e-09 36.4 1.7 4.4e-09 35.8 1.7 1.3 1 0 0 1 1 1 1 VASP tetramerisation domain WH2 PF02205.20 GAM25957.1 - 9.8e-09 34.8 0.8 2.7e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 WH2 motif DBC1 PF14443.6 GAM25958.1 - 4.5e-36 123.6 0.1 9.1e-36 122.6 0.1 1.5 1 0 0 1 1 1 1 DBC1 Aquarius_N PF16399.5 GAM25959.1 - 6.7e-199 662.8 10.5 9.4e-199 662.3 10.5 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 GAM25959.1 - 2.6e-28 99.5 0.0 6.3e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 GAM25959.1 - 3e-26 92.3 0.0 1.1e-25 90.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAM25959.1 - 3.5e-09 37.2 0.0 1.8e-08 34.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM25959.1 - 7.5e-08 32.3 0.0 0.00039 20.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 GAM25959.1 - 5.6e-06 26.5 0.0 3.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAM25959.1 - 0.00011 21.8 1.1 0.0022 17.6 0.0 3.1 3 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 GAM25959.1 - 0.0011 18.3 0.3 0.028 13.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 GAM25959.1 - 0.0012 18.7 0.0 0.0038 17.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 GAM25959.1 - 0.0013 19.2 0.4 0.033 14.6 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain UvrD_C_2 PF13538.6 GAM25959.1 - 0.0088 15.8 0.1 0.021 14.7 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 GAM25959.1 - 0.012 16.0 0.0 0.038 14.4 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAM25959.1 - 0.014 15.6 0.0 0.078 13.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.18 GAM25959.1 - 0.024 14.0 0.3 2.5 7.4 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 GAM25959.1 - 0.033 13.9 0.0 1.7 8.3 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 GAM25959.1 - 0.046 13.0 0.1 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RecA PF00154.21 GAM25959.1 - 0.056 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PhoH PF02562.16 GAM25959.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 GAM25959.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 GAM25959.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 KaiC SR-25 PF10500.9 GAM25959.1 - 0.28 10.8 3.6 0.52 9.9 3.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_23 PF13476.6 GAM25959.1 - 1.5 9.3 9.0 1.3 9.4 0.1 3.8 3 1 0 3 3 3 0 AAA domain ATP-synt_D PF01813.17 GAM25960.1 - 5e-67 225.6 5.1 5e-67 225.6 5.1 1.5 2 0 0 2 2 2 1 ATP synthase subunit D PQQ_2 PF13360.6 GAM25961.1 - 0.0001 22.0 0.0 0.00035 20.2 0.0 1.8 2 0 0 2 2 2 1 PQQ-like domain EGF_2 PF07974.13 GAM25961.1 - 0.0052 17.1 11.4 0.0052 17.1 11.4 4.1 3 1 1 4 4 4 2 EGF-like domain hEGF PF12661.7 GAM25961.1 - 0.048 14.3 7.6 0.048 14.3 7.6 3.6 3 0 0 3 3 3 0 Human growth factor-like EGF DSL PF01414.19 GAM25961.1 - 0.49 10.7 25.5 1.7 9.0 19.8 3.0 2 0 0 2 2 2 0 Delta serrate ligand HSP70 PF00012.20 GAM25962.1 - 1.4e-99 333.9 7.5 2.3e-95 320.1 0.2 3.2 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 GAM25962.1 - 0.0099 14.7 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein Methyltransf_15 PF09445.10 GAM25962.1 - 0.1 12.2 0.2 1.1 8.9 0.0 2.4 1 1 1 2 2 2 0 RNA cap guanine-N2 methyltransferase Lipoprotein_20 PF13942.6 GAM25962.1 - 0.19 11.6 4.8 0.063 13.2 1.3 2.0 2 0 0 2 2 2 0 YfhG lipoprotein NPV_P10 PF05531.12 GAM25962.1 - 1.4 9.4 4.9 1.2 9.6 1.5 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein EF-hand_1 PF00036.32 GAM25963.1 - 3.8e-21 73.0 12.2 8.6e-06 25.0 0.2 5.1 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 GAM25963.1 - 1.1e-20 71.7 8.0 6.8e-06 25.6 0.2 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 GAM25963.1 - 1.1e-19 70.7 7.0 2.7e-08 34.2 0.3 3.1 2 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 GAM25963.1 - 3.5e-15 55.6 10.3 2e-05 24.3 0.8 4.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 GAM25963.1 - 2.4e-14 52.1 14.1 1.3e-05 24.4 0.5 5.3 5 0 0 5 5 5 4 EF hand SPARC_Ca_bdg PF10591.9 GAM25963.1 - 4.4e-06 27.0 0.2 0.014 15.7 0.0 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAM25963.1 - 1.5e-05 24.8 1.6 0.052 13.5 0.1 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 GAM25963.1 - 0.0093 15.8 5.7 2.6 8.0 0.1 3.7 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 GAM25963.1 - 0.01 16.2 0.0 0.062 13.6 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain Caleosin PF05042.13 GAM25963.1 - 0.16 11.9 0.7 14 5.6 0.0 3.1 1 1 2 3 3 3 0 Caleosin related protein RCC1 PF00415.18 GAM25964.1 - 1.2e-34 118.6 6.7 3.6e-08 33.9 0.1 4.8 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM25964.1 - 5.9e-09 35.5 28.8 1.6e-05 24.6 0.6 5.5 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Sina PF03145.16 GAM25965.1 - 2.1e-09 37.6 3.0 3.2e-09 37.0 3.0 1.3 1 0 0 1 1 1 1 Seven in absentia protein family MAM33 PF02330.16 GAM25965.1 - 0.0043 17.0 4.3 0.0079 16.2 4.3 1.4 1 0 0 1 1 1 1 Mitochondrial glycoprotein Mpp10 PF04006.12 GAM25965.1 - 0.01 14.4 13.9 0.014 13.9 13.9 1.2 1 0 0 1 1 1 0 Mpp10 protein Astro_capsid_p PF12226.8 GAM25965.1 - 0.016 14.4 8.5 0.022 13.9 8.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Radial_spoke PF04712.12 GAM25965.1 - 0.067 12.1 4.7 0.13 11.2 4.7 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein GP67 PF17634.2 GAM25965.1 - 0.069 13.6 23.1 0.18 12.2 23.1 1.7 1 0 0 1 1 1 0 Gene product 67 Sigma70_ner PF04546.13 GAM25965.1 - 0.089 12.7 11.3 0.18 11.7 11.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 GAM25965.1 - 0.27 9.5 17.1 0.35 9.1 17.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Importin_rep_6 PF18829.1 GAM25965.1 - 0.3 11.2 7.4 2.7 8.2 7.4 2.3 2 0 0 2 2 2 0 Importin repeat 6 Cwf_Cwc_15 PF04889.12 GAM25965.1 - 0.4 10.4 18.5 0.74 9.5 18.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GOLD_2 PF13897.6 GAM25965.1 - 0.69 10.4 4.9 1.6 9.3 4.9 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RNA_pol_3_Rpc31 PF11705.8 GAM25965.1 - 0.71 10.1 19.7 1.4 9.1 19.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 GAM25965.1 - 0.79 9.7 10.3 1.7 8.7 10.3 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 GAM25965.1 - 0.98 9.8 29.2 2.2 8.8 29.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPP4R2 PF09184.11 GAM25965.1 - 1.2 8.7 16.1 0.44 10.1 13.5 1.5 2 0 0 2 2 2 0 PPP4R2 Sporozoite_P67 PF05642.11 GAM25965.1 - 1.4 6.9 9.5 1.8 6.6 9.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 GAM25965.1 - 1.4 7.0 20.4 2.1 6.5 20.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GAM25965.1 - 1.6 6.8 27.2 2.2 6.3 27.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 GAM25965.1 - 2.3 7.4 10.1 4 6.6 10.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FYDLN_acid PF09538.10 GAM25965.1 - 6 7.6 23.5 1.4 9.6 15.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SDA1 PF05285.12 GAM25965.1 - 7.8 5.8 20.7 13 5.1 20.7 1.3 1 0 0 1 1 1 0 SDA1 TFB6 PF17110.5 GAM25965.1 - 8.8 6.0 9.4 16 5.2 9.4 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Ank_2 PF12796.7 GAM25966.1 - 8.2e-08 32.7 8.3 0.007 16.9 0.0 5.4 3 1 2 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM25966.1 - 2.3e-07 31.2 5.3 0.071 13.7 0.0 5.4 4 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM25966.1 - 0.0021 18.3 0.1 1.2 9.6 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM25966.1 - 0.018 15.5 2.6 9.6 7.2 0.0 5.4 6 0 0 6 6 6 0 Ankyrin repeat Peptidase_C97 PF05903.14 GAM25966.1 - 0.019 14.8 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 PPPDE putative peptidase domain DUF3447 PF11929.8 GAM25966.1 - 0.041 13.9 4.7 16 5.6 2.5 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF3447) TFIIS_C PF01096.18 GAM25967.1 - 0.0077 16.1 0.1 0.025 14.4 0.1 2.0 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) PBP1_TM PF14812.6 GAM25967.1 - 0.15 12.4 5.5 0.31 11.4 5.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 GAM25967.1 - 0.2 9.8 5.1 0.26 9.4 5.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi FOXP-CC PF16159.5 GAM25967.1 - 2.3 8.9 14.6 0.58 10.8 0.7 3.5 3 0 0 3 3 3 0 FOXP coiled-coil domain Dicty_CTDC PF00526.18 GAM25969.1 - 4.3e-33 112.8 107.1 1.4e-07 31.2 16.4 8.3 8 0 0 8 8 8 8 Dictyostelium (slime mold) repeat Filamin PF00630.19 GAM25969.1 - 8.1e-13 49.1 0.3 2.1e-10 41.3 0.0 3.3 3 1 0 3 3 3 1 Filamin/ABP280 repeat DDE_Tnp_4 PF13359.6 GAM25970.1 - 5.9e-07 29.3 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2089 PF09862.9 GAM25970.1 - 0.0091 16.0 1.1 0.014 15.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2089) SDA1 PF05285.12 GAM25970.1 - 0.03 13.8 14.8 0.047 13.1 14.8 1.3 1 0 0 1 1 1 0 SDA1 HTH_Tnp_4 PF13613.6 GAM25970.1 - 0.044 13.5 0.1 0.084 12.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CDC45 PF02724.14 GAM25970.1 - 0.046 12.0 6.6 0.066 11.5 6.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Pes-10 PF07149.11 GAM25970.1 - 0.1 11.6 9.0 0.18 10.9 9.0 1.5 1 0 0 1 1 1 0 Pes-10 SpoIIID PF12116.8 GAM25970.1 - 0.12 12.4 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D DUF3172 PF11371.8 GAM25970.1 - 0.18 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) CNDH2_C PF16858.5 GAM25970.1 - 1.5 8.6 8.6 2.7 7.8 8.6 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term PTPRCAP PF15713.5 GAM25970.1 - 1.6 9.0 11.7 2.5 8.4 11.7 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2457 PF10446.9 GAM25970.1 - 7.3 5.6 21.4 14 4.7 21.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cpn60_TCP1 PF00118.24 GAM25971.1 - 2.6e-154 514.5 3.4 3e-154 514.3 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_ligase_aden PF01653.18 GAM25972.1 - 5.4e-73 245.8 0.1 9.2e-73 245.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 GAM25972.1 - 7.1e-28 96.3 2.2 2.3e-27 94.7 2.2 1.9 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 GAM25972.1 - 5.3e-12 45.7 0.0 1.5e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif BRCT PF00533.26 GAM25972.1 - 5.3e-10 39.6 0.0 1.1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 GAM25972.1 - 1.2e-09 38.6 0.7 1.7e-06 28.6 0.1 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix domain DDHD PF02862.17 GAM25972.1 - 0.0023 18.1 0.2 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 DDHD domain PTCB-BRCT PF12738.7 GAM25972.1 - 0.014 15.4 0.1 0.032 14.2 0.1 1.7 1 0 0 1 1 1 0 twin BRCT domain LIN52 PF10044.9 GAM25973.1 - 2.7e-07 31.2 0.7 4.1e-07 30.6 0.7 1.4 1 1 0 1 1 1 1 Retinal tissue protein HTH_20 PF12840.7 GAM25973.1 - 0.03 14.4 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Nif11 PF07862.11 GAM25973.1 - 0.084 13.2 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Nif11 domain DUF501 PF04417.12 GAM25973.1 - 0.15 11.9 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Ribosomal_L2_C PF03947.18 GAM25974.1 - 2.2e-46 157.2 3.4 3.8e-46 156.4 3.4 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 GAM25974.1 - 1.5e-20 72.9 0.0 7.1e-20 70.7 0.0 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Cofilin_ADF PF00241.20 GAM25975.1 - 1.5e-37 128.1 0.8 2.5e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein BolA PF01722.18 GAM25976.1 - 4.7e-14 52.4 0.0 1.4e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Chitin_synth_2 PF03142.15 GAM25976.1 - 0.053 12.1 0.0 0.06 12.0 0.0 1.0 1 0 0 1 1 1 0 Chitin synthase CLU PF13236.6 GAM25977.1 - 3.6e-56 190.5 0.0 7.7e-56 189.4 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAM25977.1 - 5.8e-06 26.5 0.7 1.4e-05 25.2 0.7 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 SurE PF01975.17 GAM25977.1 - 0.02 14.6 0.6 0.047 13.5 0.6 1.6 1 0 0 1 1 1 0 Survival protein SurE Phage_T7_tail PF03906.14 GAM25977.1 - 0.11 12.1 0.2 2.3 7.9 0.1 2.7 2 0 0 2 2 2 0 Phage T7 tail fibre protein CENP-B_dimeris PF09026.10 GAM25977.1 - 0.97 9.9 6.0 9.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain LRR_4 PF12799.7 GAM25977.1 - 5.9 7.5 6.7 1.4e+02 3.1 0.0 5.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) CLU PF13236.6 GAM25978.1 - 2.3e-54 184.6 0.0 3.8e-53 180.6 0.0 2.5 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 GAM25978.1 - 2.6e-06 27.6 0.1 9.9e-06 25.7 0.1 2.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_2 PF07719.17 GAM25978.1 - 0.037 14.1 2.0 0.16 12.2 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM25978.1 - 0.17 12.2 0.8 0.54 10.6 0.8 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 GAM25981.1 - 4.1e-68 229.6 0.0 5.2e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25981.1 - 7e-29 100.9 0.0 1e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAM25981.1 - 1.3e-05 25.8 0.0 5.2e-05 23.9 0.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 GAM25981.1 - 0.00022 20.6 0.0 0.00045 19.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAM25981.1 - 0.038 12.9 0.1 0.065 12.2 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAM25981.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM25981.1 - 0.086 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FYVE PF01363.21 GAM25982.1 - 8.8e-10 38.6 2.6 1.8e-09 37.6 2.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger WH2 PF02205.20 GAM25982.1 - 0.0067 16.2 0.3 0.023 14.5 0.3 2.0 1 0 0 1 1 1 1 WH2 motif Pkinase PF00069.25 GAM25982.1 - 0.0091 15.4 0.2 0.024 14.0 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM25982.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase HIT PF01230.23 GAM25983.1 - 3e-26 92.0 0.0 3.7e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAM25983.1 - 1e-07 32.4 0.0 1.2e-07 32.2 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 GAM25983.1 - 0.064 13.1 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 FNIP PF05725.12 GAM25984.1 - 3.1e-15 56.1 26.9 2e-07 31.1 0.1 7.9 3 2 5 9 9 9 7 FNIP Repeat Peptidase_C58 PF03543.14 GAM25984.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen FNIP PF05725.12 GAM25985.1 - 2.9e-76 251.4 27.7 2e-13 50.3 0.1 10.4 5 3 4 10 10 10 9 FNIP Repeat NOA36 PF06524.12 GAM25988.1 - 0.078 12.3 2.9 0.12 11.7 2.9 1.3 1 0 0 1 1 1 0 NOA36 protein Kelch_3 PF13415.6 GAM25989.1 - 1.7e-42 142.9 9.6 1.4e-10 41.2 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM25989.1 - 8.4e-39 130.6 9.3 7e-11 42.0 0.0 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 GAM25989.1 - 1.7e-37 126.7 11.0 7.9e-07 28.6 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 GAM25989.1 - 1.8e-37 127.1 10.7 2.1e-11 43.7 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM25989.1 - 2e-32 109.9 15.6 4.9e-07 29.5 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 GAM25989.1 - 2.4e-31 107.2 15.9 7e-06 25.9 0.3 6.7 7 0 0 7 7 7 6 Kelch motif SAM_2 PF07647.17 GAM25989.1 - 9.1e-11 41.7 0.2 1.7e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAM25989.1 - 1.8e-09 37.9 0.1 3.5e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 GAM25989.1 - 0.00082 19.3 0.4 0.0059 16.5 0.2 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PQQ_3 PF13570.6 GAM25989.1 - 0.0073 16.8 1.2 6.2 7.4 0.1 4.3 5 0 0 5 5 5 1 PQQ-like domain RAG2 PF03089.14 GAM25989.1 - 0.068 12.1 0.4 4.6 6.1 0.0 3.5 3 2 1 4 4 4 0 Recombination activating protein 2 Say1_Mug180 PF10340.9 GAM25989.1 - 0.07 12.0 0.2 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase EVI2A PF05399.11 GAM25989.1 - 0.66 9.5 5.2 1 8.9 5.2 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Suf PF05843.14 GAM25989.1 - 2.4 8.0 6.3 3.7 7.5 6.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Glyco_hydro_16 PF00722.21 GAM25990.1 - 4.8e-10 39.2 0.0 6e-09 35.6 0.0 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Ndc1_Nup PF09531.10 GAM25990.1 - 0.034 12.8 3.5 0.044 12.5 3.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FMN_red PF03358.15 GAM25991.1 - 1.2e-22 80.3 0.0 1.6e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAM25991.1 - 3.9e-06 26.7 0.0 5.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Toast_rack_N PF17115.5 GAM25992.1 - 0.068 13.5 0.1 0.21 11.9 0.0 1.8 2 1 0 2 2 2 0 N-terminal domain of toast_rack, DUF2154 PFK PF00365.20 GAM25995.1 - 1.4e-189 628.3 3.6 4.2e-107 357.7 0.9 2.1 2 0 0 2 2 2 2 Phosphofructokinase CBS PF00571.28 GAM25995.1 - 0.036 14.5 0.0 1.9 9.0 0.0 3.3 3 0 0 3 3 3 0 CBS domain NYN PF01936.18 GAM25996.1 - 2.8e-22 79.8 0.2 2.8e-22 79.8 0.2 3.1 2 1 0 2 2 2 1 NYN domain AMPK1_CBM PF16561.5 GAM25996.1 - 4.9e-20 71.5 9.1 8.4e-14 51.6 0.0 3.9 4 0 0 4 4 4 2 Glycogen recognition site of AMP-activated protein kinase OHA PF14418.6 GAM25996.1 - 1.2e-15 57.1 0.0 3.7e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 OST-HTH Associated domain Hid1 PF12722.7 GAM25996.1 - 0.0012 17.1 25.1 0.0012 17.1 25.1 2.2 3 0 0 3 3 3 1 High-temperature-induced dauer-formation protein Med15 PF09606.10 GAM25996.1 - 0.02 13.6 82.0 0.04 12.6 82.0 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MINDY_DUB PF04424.13 GAM25997.1 - 8e-26 90.4 0.7 1.8e-25 89.3 0.7 1.6 1 0 0 1 1 1 1 MINDY deubiquitinase UBA PF00627.31 GAM25997.1 - 0.081 12.9 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain DUF21 PF01595.20 GAM25998.1 - 3.3e-34 118.1 1.6 5.3e-34 117.4 1.6 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GAM25998.1 - 3.4e-06 27.4 0.1 0.077 13.5 0.1 2.6 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 GAM25998.1 - 0.034 14.2 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Dicty_REP PF05086.12 GAM25998.1 - 0.68 7.8 4.2 0.94 7.4 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cornichon PF03311.14 GAM25999.1 - 3.5e-35 121.0 10.3 4.3e-35 120.7 10.3 1.0 1 0 0 1 1 1 1 Cornichon protein TMEM237 PF15383.6 GAM25999.1 - 0.1 11.7 0.2 0.1 11.7 0.2 1.7 2 1 1 3 3 3 0 Transmembrane protein 237 p450 PF00067.22 GAM26000.1 - 9.8e-99 331.2 0.0 1.1e-98 331.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAM26001.1 - 7.3e-25 87.6 0.0 7.7e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 GAM26002.1 - 1e-54 185.7 0.0 1.6e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26002.1 - 1.2e-52 178.8 0.0 1.8e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM26002.1 - 0.0051 16.2 0.1 0.0082 15.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM26002.1 - 0.012 14.6 0.1 0.012 14.6 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 GAM26002.1 - 0.037 14.0 0.1 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM26002.1 - 0.11 11.2 1.1 0.15 10.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase GAGA_bind PF06217.12 GAM26003.1 - 0.042 14.1 6.6 0.11 12.7 6.6 1.7 1 0 0 1 1 1 0 GAGA binding protein-like family TTR-52 PF01060.23 GAM26003.1 - 0.11 13.2 0.9 2.9 8.7 0.0 3.4 4 0 0 4 4 4 0 Transthyretin-like family RR_TM4-6 PF06459.12 GAM26003.1 - 0.25 11.1 16.3 0.65 9.8 16.3 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.6 GAM26003.1 - 1.4 9.4 16.2 0.69 10.4 12.1 2.7 2 0 0 2 2 2 0 AAA domain Cadherin-like PF12733.7 GAM26003.1 - 1.6 9.3 5.9 3.1 8.4 0.4 3.4 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain AAA_11 PF13086.6 GAM26003.1 - 1.7 8.4 9.5 3.5 7.3 9.5 1.4 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.11 GAM26003.1 - 1.8 7.0 18.6 0.28 9.6 14.4 1.8 2 0 0 2 2 2 0 Borrelia P83/100 protein CDC27 PF09507.10 GAM26003.1 - 3.8 6.8 29.7 7.9 5.7 29.7 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zip PF02535.22 GAM26003.1 - 5.5 6.1 5.0 9.6 5.3 5.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TPR_1 PF00515.28 GAM26004.1 - 6.9e-06 25.7 0.1 0.0031 17.3 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM26004.1 - 9.6e-05 22.8 0.7 0.074 13.6 0.0 3.2 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM26004.1 - 0.00044 20.2 0.4 0.013 15.6 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM26004.1 - 0.0038 17.8 0.1 0.014 16.0 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM26004.1 - 0.0071 17.1 1.3 4 8.5 0.0 3.6 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM26004.1 - 0.011 15.9 0.1 3.1 8.0 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAM26004.1 - 0.018 15.4 0.0 8.8 7.0 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.8 GAM26004.1 - 0.03 13.2 0.1 1.6 7.5 0.0 2.2 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 DUF4259 PF14078.6 GAM26004.1 - 0.065 14.0 0.0 0.99 10.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) TPR_2 PF07719.17 GAM26004.1 - 0.079 13.1 0.1 21 5.5 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAM26004.1 - 0.083 13.2 0.1 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM26004.1 - 0.15 12.2 0.0 3 8.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 GAM26006.1 - 0.38 11.2 9.5 1.1 9.7 9.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C2H2_aberr PF17017.5 GAM26007.1 - 1.3 9.2 19.4 1.6 8.8 0.3 3.8 3 1 1 4 4 4 0 Aberrant zinc-finger DEAD PF00270.29 GAM26008.1 - 1.1e-51 175.1 0.5 5.9e-51 172.7 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM26008.1 - 2.1e-27 95.6 0.0 1e-26 93.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Herpes_BBRF1 PF04793.12 GAM26009.1 - 0.0045 16.1 0.0 0.005 15.9 0.0 1.1 1 0 0 1 1 1 1 BRRF1-like protein PAP2 PF01569.21 GAM26010.1 - 1.2e-15 57.5 2.1 1.2e-15 57.5 2.1 2.0 1 1 1 2 2 2 1 PAP2 superfamily UbiA PF01040.18 GAM26010.1 - 0.0011 18.3 3.1 0.0011 18.3 3.1 1.9 2 0 0 2 2 2 1 UbiA prenyltransferase family SAF PF08666.12 GAM26010.1 - 0.11 13.1 0.0 7.6 7.3 0.0 2.9 2 1 1 3 3 3 0 SAF domain PikAIV_N PF18605.1 GAM26010.1 - 0.25 11.0 0.3 0.44 10.2 0.3 1.4 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF805 PF05656.14 GAM26010.1 - 0.84 10.1 4.7 1.5 9.3 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Transmemb_17 PF09799.9 GAM26010.1 - 1.7 9.3 9.0 0.37 11.4 4.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein DUF4199 PF13858.6 GAM26010.1 - 2.3 8.6 12.2 4.1 7.8 8.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) Ank_2 PF12796.7 GAM26011.1 - 5.9e-05 23.6 0.1 0.5 11.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM26011.1 - 0.0077 16.7 0.7 27 5.8 0.0 5.5 5 1 1 6 6 6 1 Ankyrin repeat SCAI PF12070.8 GAM26012.1 - 8.8e-203 675.0 4.7 8.8e-203 675.0 4.7 1.8 2 0 0 2 2 2 1 Protein SCAI SR-25 PF10500.9 GAM26012.1 - 2.3 7.8 18.7 0.56 9.8 8.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CCDC53 PF10152.9 GAM26012.1 - 4.3 7.7 8.6 1.9 8.9 0.1 2.6 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex DUF1635 PF07795.11 GAM26012.1 - 5 6.9 18.1 0.47 10.3 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) DUF4041 PF13250.6 GAM26013.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) dNK PF01712.19 GAM26014.1 - 2.6e-38 131.9 4.1 3.5e-38 131.5 4.1 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 GAM26014.1 - 6.3e-05 22.7 0.2 8.7e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 GAM26014.1 - 0.035 14.7 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Herpes_TK PF00693.18 GAM26014.1 - 0.065 12.5 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus DUF4336 PF14234.6 GAM26014.1 - 0.09 12.0 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) zf-Tim10_DDP PF02953.15 GAM26015.1 - 7.4e-10 38.3 7.1 7.4e-10 38.3 7.1 1.9 1 1 1 2 2 2 1 Tim10/DDP family zinc finger DUF3848 PF12959.7 GAM26015.1 - 0.023 14.7 0.4 0.03 14.4 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3848) Pex2_Pex12 PF04757.14 GAM26016.1 - 6.7e-38 130.5 4.4 8.6e-38 130.2 4.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 GAM26016.1 - 6.4e-06 26.0 11.2 9.9e-06 25.4 11.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAM26016.1 - 8.6e-06 25.5 12.6 1.4e-05 24.8 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM26016.1 - 2.8e-05 24.0 12.6 5.1e-05 23.2 12.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAM26016.1 - 4.5e-05 23.2 9.1 6.6e-05 22.7 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM26016.1 - 0.00016 21.4 12.8 0.00028 20.6 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM26016.1 - 0.00023 21.4 12.3 0.00036 20.8 12.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 GAM26016.1 - 0.0091 16.1 15.1 0.016 15.3 15.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAM26016.1 - 0.022 14.6 12.2 0.2 11.6 12.7 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GAM26016.1 - 0.24 11.6 4.7 0.44 10.7 4.7 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 GAM26016.1 - 1.2 9.5 6.7 2.6 8.4 6.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain DZR PF12773.7 GAM26016.1 - 2.5 8.2 7.2 4.7 7.3 7.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Dicty_CTDC PF00526.18 GAM26017.1 - 4.7e-124 403.7 391.6 1.4e-09 37.7 11.5 29.3 29 0 0 29 29 29 28 Dictyostelium (slime mold) repeat Dicty_CTDC PF00526.18 GAM26020.1 - 1.1e-143 466.4 580.7 4.4e-07 29.7 10.7 42.9 43 0 0 43 43 43 35 Dictyostelium (slime mold) repeat zf-TAZ PF02135.16 GAM26020.1 - 6.5e-17 61.8 199.9 0.00084 19.8 5.2 19.8 1 1 25 26 26 26 20 TAZ zinc finger RXT2_N PF08595.11 GAM26022.1 - 0.028 14.4 2.9 0.047 13.7 2.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Mif2_N PF15624.6 GAM26022.1 - 0.058 14.1 1.5 0.13 13.0 1.5 1.6 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Nop14 PF04147.12 GAM26022.1 - 0.1 10.8 7.1 0.14 10.4 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAM26022.1 - 0.15 11.5 6.0 0.22 10.9 6.0 1.2 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 GAM26022.1 - 0.28 9.6 9.0 0.38 9.1 9.0 1.1 1 0 0 1 1 1 0 Mpp10 protein Astro_capsid_p PF12226.8 GAM26022.1 - 0.45 9.6 9.6 0.67 9.0 9.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sporozoite_P67 PF05642.11 GAM26022.1 - 0.64 8.0 3.5 0.81 7.7 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 GAM26022.1 - 0.88 7.8 5.9 1.2 7.3 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAM26022.1 - 1.9 6.5 18.2 2.8 5.9 18.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 GAM26022.1 - 2.4 8.4 13.7 4.4 7.5 13.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 GAM26022.1 - 2.4 7.8 5.3 5.5 6.6 5.3 1.6 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 GAM26022.1 - 5.8 6.0 5.4 8.8 5.4 5.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Glyco_hydro_18 PF00704.28 GAM26023.1 - 4.6e-22 79.1 0.3 6.2e-22 78.7 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM49 PF09478.10 GAM26023.1 - 1.3e-13 51.0 1.0 1.3e-13 51.0 1.0 2.2 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 Methyltransf_16 PF10294.9 GAM26024.1 - 1.7e-22 80.0 0.0 2.8e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 GAM26024.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 GAM26024.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAM26024.1 - 0.067 13.9 0.0 0.17 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAM26024.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 GAM26024.1 - 0.16 12.7 0.0 0.5 11.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain CLU PF13236.6 GAM26025.1 - 4.8e-53 180.2 0.0 1e-52 179.2 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria Ras PF00071.22 GAM26025.1 - 1.4e-37 128.8 0.2 2.8e-37 127.8 0.2 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM26025.1 - 5.3e-22 78.3 0.3 1.6e-21 76.8 0.3 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM26025.1 - 1.7e-09 37.4 0.3 2.9e-09 36.6 0.3 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family eIF3_p135 PF12807.7 GAM26025.1 - 2.5e-05 24.4 0.1 0.00014 22.0 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_17 PF13431.6 GAM26025.1 - 0.013 15.9 0.8 7.3 7.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_60s PF00428.19 GAM26025.1 - 0.036 14.7 0.0 0.15 12.7 0.0 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sharpin_PH PF16764.5 GAM26025.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Sharpin PH domain TPR_19 PF14559.6 GAM26025.1 - 0.15 12.6 0.0 0.95 10.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM26025.1 - 0.54 10.5 3.7 1.6 9.1 0.0 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 GAM26026.1 - 2.4e-64 217.1 0.0 3.3e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM26026.1 - 9.1e-59 199.0 0.0 1.8e-58 198.0 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain APH PF01636.23 GAM26026.1 - 0.0066 16.4 3.6 0.031 14.2 0.6 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Myc_target_1 PF15179.6 GAM26026.1 - 0.023 14.6 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Myc target protein 1 RIO1 PF01163.22 GAM26026.1 - 0.065 12.8 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Slu7 PF11708.8 GAM26027.1 - 4e-86 289.1 9.2 4e-86 289.1 9.2 3.9 3 1 1 4 4 4 1 Pre-mRNA splicing Prp18-interacting factor DUF4148 PF13663.6 GAM26027.1 - 0.069 13.3 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) DHQ_synthase PF01761.20 GAM26027.1 - 0.078 12.1 5.2 0.21 10.7 5.2 1.7 1 0 0 1 1 1 0 3-dehydroquinate synthase zf-CCHC_4 PF14392.6 GAM26027.1 - 0.41 10.4 2.6 0.93 9.3 2.6 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 GAM26027.1 - 0.47 10.6 3.1 0.44 10.7 1.6 1.7 2 0 0 2 2 2 0 Zinc knuckle Zip PF02535.22 GAM26027.1 - 7.7 5.6 9.6 16 4.5 9.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter PCI PF01399.27 GAM26028.1 - 1.6e-18 67.1 0.0 1.6e-18 67.1 0.0 2.9 3 2 0 3 3 3 1 PCI domain Rpn3_C PF08375.11 GAM26028.1 - 2.6e-18 66.2 0.1 6.4e-18 64.9 0.1 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 GAM26028.1 - 0.01 15.9 1.1 0.24 11.6 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1548 PF07579.11 GAM26028.1 - 0.15 12.4 5.4 4.1 7.7 0.1 3.2 2 1 2 4 4 4 0 Domain of Unknown Function (DUF1548) LIDHydrolase PF10230.9 GAM26030.1 - 1.8e-54 185.1 0.0 2.1e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 GAM26030.1 - 5.3e-05 23.0 0.3 0.00091 18.9 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM26030.1 - 0.00023 20.5 0.0 0.00033 20.0 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM26030.1 - 0.011 16.4 0.0 0.017 15.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 GAM26030.1 - 0.034 13.8 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF4239 PF14023.6 GAM26032.1 - 0.055 13.2 0.4 0.055 13.2 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) NLRC4_HD2 PF17776.1 GAM26032.1 - 0.24 11.9 0.2 0.24 11.9 0.2 2.5 1 1 1 2 2 2 0 NLRC4 helical domain HD2 FERM_f0 PF16511.5 GAM26033.1 - 7e-25 87.1 2.7 3.6e-16 59.2 0.0 4.2 4 0 0 4 4 4 3 N-terminal or F0 domain of Talin-head FERM RhoGAP PF00620.27 GAM26033.1 - 4.9e-12 45.9 0.0 1.3e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain MACPF PF01823.19 GAM26034.1 - 6.8e-20 72.1 1.3 6.8e-20 72.1 1.3 2.4 2 1 0 2 2 2 1 MAC/Perforin domain MACPF PF01823.19 GAM26035.1 - 4.2e-18 66.2 2.4 1.1e-17 64.8 2.4 1.7 1 0 0 1 1 1 1 MAC/Perforin domain D123 PF07065.14 GAM26035.1 - 0.24 10.5 0.6 0.41 9.8 0.6 1.2 1 0 0 1 1 1 0 D123 DNase_II PF03265.15 GAM26038.1 - 1.4e-09 37.7 0.8 5.2e-09 35.8 0.1 1.9 1 1 0 2 2 2 1 Deoxyribonuclease II Mucin PF01456.17 GAM26038.1 - 0.0057 16.7 15.1 0.011 15.8 15.1 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.8 GAM26038.1 - 0.016 15.2 10.6 0.03 14.3 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.11 GAM26038.1 - 0.061 11.4 7.3 0.094 10.8 7.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 GAM26038.1 - 0.45 8.7 13.0 0.56 8.3 13.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 EF-hand_7 PF13499.6 GAM26039.1 - 0.093 13.2 2.7 0.33 11.4 2.6 2.0 1 1 0 1 1 1 0 EF-hand domain pair FNIP PF05725.12 GAM26040.1 - 4.4e-90 295.6 28.0 1.9e-14 53.5 1.1 9.7 2 2 6 12 12 12 11 FNIP Repeat Tecti-min-caps PF09300.10 GAM26040.1 - 0.15 12.2 0.1 13 5.9 0.0 3.9 3 1 1 4 4 4 0 Tectiviridae, minor capsid Aldedh PF00171.22 GAM26041.1 - 3.5e-126 421.4 0.0 4.2e-126 421.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family M11L PF11099.8 GAM26043.1 - 0.049 13.9 0.0 0.053 13.8 0.0 1.0 1 0 0 1 1 1 0 Apoptosis regulator M11L like GATA PF00320.27 GAM26044.1 - 1.4e-07 31.0 4.5 3e-07 29.9 4.5 1.6 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.31 GAM26044.1 - 3.5e-06 27.1 0.1 9.3e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM26044.1 - 0.04 14.2 2.5 0.11 12.8 2.5 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Nudix_N_2 PF14803.6 GAM26044.1 - 0.42 10.6 3.0 1 9.3 3.0 1.6 1 0 0 1 1 1 0 Nudix N-terminal DUF3221 PF11518.8 GAM26044.1 - 5.8 7.4 6.6 7.5 7.0 0.8 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) PX PF00787.24 GAM26045.1 - 8.9e-20 70.8 3.4 1.1e-19 70.4 3.4 1.1 1 0 0 1 1 1 1 PX domain PQ-loop PF04193.14 GAM26046.1 - 2.7e-10 39.9 27.8 1.5e-06 27.9 7.0 2.9 3 0 0 3 3 3 2 PQ loop repeat HATPase_c PF02518.26 GAM26047.1 - 3.4e-25 88.7 0.0 6.8e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM26047.1 - 1e-19 70.7 0.1 3.3e-19 69.1 0.1 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAM26047.1 - 4.5e-17 61.8 0.0 1.3e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 GAM26047.1 - 0.00012 22.4 0.0 0.00023 21.5 0.0 1.4 1 0 0 1 1 1 1 GAF domain PAS_4 PF08448.10 GAM26047.1 - 0.0064 16.7 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 GAM26047.1 - 0.036 14.3 0.1 0.099 12.9 0.1 1.8 1 0 0 1 1 1 0 PAS domain DUF4904 PF16247.5 GAM26048.1 - 0.048 13.5 0.1 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4904) Presenilin PF01080.17 GAM26048.1 - 0.26 10.0 11.8 0.35 9.6 11.8 1.2 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 GAM26048.1 - 0.91 7.4 11.2 1.1 7.1 11.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3464 PF11947.8 GAM26048.1 - 6.1 6.6 15.6 0.069 12.9 2.4 2.3 1 1 1 2 2 2 0 Photosynthesis affected mutant 68 Peptidase_S28 PF05577.12 GAM26049.1 - 3.8e-74 250.0 3.7 2.1e-42 145.4 0.1 2.2 1 1 1 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.7 GAM26049.1 - 3.1e-05 24.7 0.2 0.00013 22.7 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAM26049.1 - 0.00066 19.2 0.2 0.0014 18.2 0.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAM26049.1 - 0.0009 19.0 0.2 0.004 16.8 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.11 GAM26049.1 - 0.013 14.2 0.0 0.022 13.4 0.0 1.4 1 0 0 1 1 1 0 PS-10 peptidase S37 Hydrolase_4 PF12146.8 GAM26049.1 - 0.018 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2920 PF11144.8 GAM26049.1 - 0.06 12.5 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Malic_M PF03949.15 GAM26049.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Oxysterol_BP PF01237.18 GAM26050.1 - 3e-56 190.8 7.1 1.2e-55 188.9 7.1 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein Peptidase_M41 PF01434.18 GAM26051.1 - 4.8e-65 219.0 0.2 7e-65 218.5 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAM26051.1 - 2.4e-42 144.5 0.0 6.4e-42 143.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM26051.1 - 4e-11 42.5 0.1 1e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAM26051.1 - 5.4e-05 23.2 0.0 0.0003 20.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM26051.1 - 0.00033 20.9 0.2 0.27 11.5 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GAM26051.1 - 0.0019 18.6 0.2 0.23 11.8 0.2 3.2 2 1 0 3 3 3 1 AAA ATPase domain FtsH_ext PF06480.15 GAM26051.1 - 0.0038 17.6 0.0 0.0038 17.6 0.0 2.5 3 1 0 3 3 3 1 FtsH Extracellular TIP49 PF06068.13 GAM26051.1 - 0.0081 15.4 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 GAM26051.1 - 0.0085 16.3 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAM26051.1 - 0.012 15.3 0.0 0.044 13.5 0.0 2.0 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAM26051.1 - 0.014 16.0 0.3 4.2 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 GAM26051.1 - 0.038 14.1 0.0 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 GAM26051.1 - 0.066 12.6 0.3 0.19 11.1 0.2 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GAM26051.1 - 0.085 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAM26051.1 - 0.098 12.4 1.2 0.18 11.5 0.2 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Rav1p_C PF12234.8 GAM26052.1 - 5.9e-86 289.3 3.4 6e-86 289.3 0.0 2.6 3 0 0 3 3 3 1 RAVE protein 1 C terminal WD40 PF00400.32 GAM26052.1 - 4.4e-10 40.0 18.6 0.054 14.4 0.1 10.4 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM26052.1 - 4.3e-05 23.7 0.1 0.025 14.9 0.0 4.2 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain ABC2_membrane_3 PF12698.7 GAM26052.1 - 0.4 9.7 3.4 0.8 8.7 3.4 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Glycos_transf_1 PF00534.20 GAM26053.1 - 2.4e-26 92.3 0.0 3.6e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 GAM26053.1 - 2.5e-23 82.7 0.0 5.8e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_1_4 PF13692.6 GAM26053.1 - 1.1e-19 71.1 0.0 2.3e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tranf_2_2 PF10111.9 GAM26053.1 - 3.7e-11 43.0 0.0 4e-10 39.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 GAM26053.1 - 8.6e-09 35.6 0.0 2.3e-07 31.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_4 PF13439.6 GAM26053.1 - 2e-08 34.5 0.0 4.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_2_3 PF13632.6 GAM26053.1 - 6.4e-05 23.0 0.5 0.00028 20.9 0.5 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_trans_1_2 PF13524.6 GAM26053.1 - 0.00011 22.5 0.0 0.00029 21.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_7C PF02709.14 GAM26053.1 - 0.032 13.9 0.6 0.098 12.3 0.6 1.8 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Cytokin_check_N PF10407.9 GAM26055.1 - 0.035 14.1 0.0 0.19 11.7 0.0 2.1 1 1 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus Codanin-1_C PF15296.6 GAM26055.1 - 0.46 10.6 7.3 0.92 9.6 7.3 1.4 1 0 0 1 1 1 0 Codanin-1 C-terminus RNA_pol_Rpc34 PF05158.12 GAM26056.1 - 3.7e-57 194.2 4.8 1.5e-38 133.0 3.1 2.1 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 GAM26056.1 - 0.00031 20.8 1.2 0.0018 18.4 0.2 2.5 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC RPA_C PF08784.11 GAM26056.1 - 0.00067 20.3 2.4 1.5 9.5 0.1 3.1 2 2 1 3 3 3 2 Replication protein A C terminal TrmB PF01978.19 GAM26056.1 - 0.0016 18.3 0.2 0.12 12.3 0.1 2.9 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 GAM26056.1 - 0.045 13.6 0.3 4.9 7.1 0.1 3.0 3 0 0 3 3 3 0 MarR family RibD_C PF01872.17 GAM26056.1 - 0.058 13.2 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain TFIIE_beta PF02186.15 GAM26056.1 - 0.34 11.2 3.0 2.4 8.5 0.0 3.0 2 1 0 3 3 3 0 TFIIE beta subunit core domain Rubis-subs-bind PF09273.11 GAM26057.1 - 4.3e-22 79.2 1.8 8.8e-22 78.2 1.8 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 GAM26057.1 - 1.6e-14 54.6 0.1 4.2e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 SET domain OsmC PF02566.19 GAM26059.1 - 2.6e-17 63.1 0.3 3.1e-17 62.9 0.3 1.1 1 0 0 1 1 1 1 OsmC-like protein Prefoldin_2 PF01920.20 GAM26060.1 - 5.5e-12 45.6 9.2 7.2e-12 45.2 9.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 GAM26060.1 - 0.012 15.6 9.3 0.022 14.7 2.7 2.2 2 0 0 2 2 2 0 Prefoldin subunit RNA_polI_A14 PF08203.11 GAM26060.1 - 0.024 15.3 2.0 0.5 11.1 0.1 2.2 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 DUF2714 PF10896.8 GAM26060.1 - 0.071 13.2 2.2 5.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2714) KxDL PF10241.9 GAM26060.1 - 0.077 13.3 2.9 1.7 9.0 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein V_ATPase_I PF01496.19 GAM26060.1 - 0.16 9.9 4.7 0.19 9.6 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 GAM26060.1 - 0.65 10.2 6.6 5.7 7.1 6.5 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5320 PF17253.2 GAM26060.1 - 1 10.4 3.5 2.4 9.3 0.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF4337 PF14235.6 GAM26060.1 - 3 7.9 10.0 1.8 8.7 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Sec34 PF04136.15 GAM26061.1 - 1.4e-30 106.1 8.6 1.4e-30 106.1 8.6 2.6 2 0 0 2 2 2 1 Sec34-like family FlaC_arch PF05377.11 GAM26061.1 - 0.18 12.3 1.3 3 8.3 0.1 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) RasGAP PF00616.19 GAM26062.1 - 4.1e-35 121.4 0.0 4.1e-35 121.4 0.0 4.3 4 2 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 GAM26062.1 - 2.6e-32 111.3 1.2 6.2e-15 55.3 0.0 4.2 3 0 0 3 3 3 3 Calponin homology (CH) domain CENP-B_dimeris PF09026.10 GAM26063.1 - 0.0004 20.7 16.2 0.0004 20.7 16.2 2.6 2 0 0 2 2 2 1 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.8 GAM26063.1 - 0.003 17.9 15.9 0.003 17.9 15.9 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 GAM26063.1 - 0.0064 16.3 13.1 0.0064 16.3 13.1 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein TRAP_alpha PF03896.16 GAM26063.1 - 0.0081 15.4 4.4 0.0081 15.4 4.4 1.7 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Afi1 PF07792.12 GAM26063.1 - 1.8 9.1 13.5 0.13 12.8 5.3 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nop14 PF04147.12 GAM26063.1 - 1.8 6.7 14.1 0.017 13.4 5.2 1.8 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.12 GAM26063.1 - 2.1 7.6 35.3 0.071 12.4 21.7 3.0 3 0 0 3 3 3 0 NOA36 protein RXT2_N PF08595.11 GAM26063.1 - 4.2 7.4 17.9 0.16 12.0 6.9 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Ank_3 PF13606.6 GAM26064.1 - 1.4 9.7 16.7 71 4.5 0.3 8.7 10 0 0 10 10 10 0 Ankyrin repeat Ank_4 PF13637.6 GAM26064.1 - 2.2 9.0 10.5 11 6.8 0.1 5.8 7 1 1 8 8 8 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM26065.1 - 5.6e-06 26.9 1.2 1.5 9.5 0.0 4.5 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26065.1 - 0.0074 16.8 0.3 25 5.6 0.0 4.5 4 2 2 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26065.1 - 0.052 14.1 0.3 1.3e+02 3.7 0.1 5.3 6 1 1 7 7 7 0 Ankyrin repeat Ank_2 PF12796.7 GAM26066.1 - 1.4e-08 35.2 12.5 0.13 12.8 1.4 8.9 9 2 2 11 11 11 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM26066.1 - 0.096 13.3 17.7 1.3e+02 3.7 0.3 10.3 12 1 0 13 13 13 0 Ankyrin repeat Ank_4 PF13637.6 GAM26066.1 - 0.13 12.9 12.0 41 4.9 0.0 7.5 8 2 3 11 11 11 0 Ankyrin repeats (many copies) Cyto_heme_lyase PF01265.17 GAM26067.1 - 3.5e-58 197.5 7.8 2.6e-57 194.7 7.8 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF2963 PF11178.8 GAM26067.1 - 0.14 11.9 1.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) tRNA_bind PF01588.20 GAM26068.1 - 3.5e-19 68.7 0.1 6.4e-13 48.6 0.0 2.2 1 1 1 2 2 2 2 Putative tRNA binding domain Nuc_sug_transp PF04142.15 GAM26069.1 - 4e-09 36.1 6.0 6.5e-09 35.4 6.0 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 GAM26069.1 - 4.8e-09 36.0 14.5 1.4e-06 27.8 0.6 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 GAM26069.1 - 2.8e-06 27.6 23.9 2.5e-05 24.5 2.0 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAM26069.1 - 2.6e-05 23.6 18.2 7.1e-05 22.2 18.2 1.8 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 GAM26069.1 - 8.4e-05 21.7 6.4 8.4e-05 21.7 6.4 1.9 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 GAM26069.1 - 0.0015 17.8 18.5 0.0089 15.3 18.5 2.3 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport AAA PF00004.29 GAM26070.1 - 4.3e-07 30.4 0.2 1.6e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAM26070.1 - 4.4e-07 30.0 0.4 6.5e-06 26.2 0.1 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 GAM26070.1 - 3.4e-05 24.1 0.0 0.0001 22.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAM26070.1 - 0.01 16.0 0.2 0.043 14.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAM26070.1 - 0.013 15.0 0.1 0.03 13.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 GAM26070.1 - 0.014 15.8 0.0 0.064 13.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase TniB PF05621.11 GAM26070.1 - 0.023 14.1 0.0 6.4 6.1 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 GAM26070.1 - 0.026 14.5 0.5 0.075 12.9 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 GAM26070.1 - 0.033 14.2 0.0 0.12 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAM26070.1 - 0.037 14.6 0.0 0.2 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAM26070.1 - 0.13 12.6 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 GAM26070.1 - 0.15 12.3 0.0 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAM26070.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 GAM26070.1 - 1.3 9.5 14.6 0.67 10.4 0.2 2.7 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.6 GAM26071.1 - 0.0038 17.5 2.4 3.8 7.9 0.2 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat Condensin2nSMC PF12422.8 GAM26071.1 - 0.014 15.6 3.3 0.93 9.7 0.4 2.4 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit RPN6_N PF18055.1 GAM26071.1 - 0.11 12.9 6.1 0.7 10.3 0.6 3.1 3 1 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain PIG-P PF08510.12 GAM26072.1 - 2.2e-35 121.2 6.7 2.2e-35 121.2 6.7 1.9 2 0 0 2 2 2 1 PIG-P OATP PF03137.20 GAM26072.1 - 0.0036 15.7 0.3 0.0036 15.7 0.3 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Vma12 PF11712.8 GAM26072.1 - 0.0048 17.0 0.5 0.0048 17.0 0.5 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Otopetrin PF03189.13 GAM26072.1 - 0.011 14.6 0.1 0.011 14.6 0.1 1.7 2 0 0 2 2 2 0 Otopetrin DUF2417 PF10329.9 GAM26072.1 - 0.017 14.5 0.1 0.038 13.4 0.1 1.5 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Connexin PF00029.19 GAM26072.1 - 0.021 14.6 0.3 0.038 13.8 0.3 1.5 1 0 0 1 1 1 0 Connexin FHIPEP PF00771.20 GAM26072.1 - 0.096 11.1 1.7 0.14 10.6 1.7 1.1 1 0 0 1 1 1 0 FHIPEP family DUF1279 PF06916.13 GAM26072.1 - 0.14 12.7 1.7 0.28 11.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) G0-G1_switch_2 PF15103.6 GAM26072.1 - 0.17 12.3 2.6 12 6.4 3.6 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 DPM2 PF07297.12 GAM26072.1 - 0.18 12.1 11.9 0.33 11.3 11.9 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) eIF-3_zeta PF05091.12 GAM26072.1 - 0.23 10.4 8.3 0.35 9.8 8.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 GAM26072.1 - 0.59 9.4 7.8 0.21 10.9 4.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Roughex PF06020.11 GAM26072.1 - 2.2 7.3 8.2 4.3 6.3 8.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein AIF_C PF14721.6 GAM26072.1 - 2.3 8.6 6.5 1.1 9.6 1.2 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Suf PF05843.14 GAM26072.1 - 5.5 6.9 13.9 0.26 11.2 7.3 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) EIIBC-GUT_N PF03612.14 GAM26072.1 - 5.8 6.6 8.8 0.3 10.8 3.4 1.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus CBM_25 PF03423.13 GAM26072.1 - 5.9 7.2 9.4 14 6.0 9.4 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Spt20 PF12090.8 GAM26072.1 - 9.3 5.8 38.3 0.65 9.6 28.9 2.4 2 0 0 2 2 2 0 Spt20 family DUF1084 PF06454.11 GAM26073.1 - 1.7e-22 80.1 21.6 3.3e-22 79.2 21.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) DUF2207 PF09972.9 GAM26073.1 - 0.085 11.6 0.0 0.085 11.6 0.0 2.6 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3007 PF11460.8 GAM26073.1 - 0.28 11.4 6.4 6.8 7.0 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) Beach PF02138.18 GAM26074.1 - 8.9e-121 402.5 0.4 2e-120 401.3 0.4 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAM26074.1 - 1.3e-14 54.1 0.0 3.5e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 GAM26074.1 - 3.6e-09 37.1 15.3 0.0093 16.8 1.1 7.0 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40_like PF17005.5 GAM26074.1 - 0.00079 18.8 0.4 0.02 14.2 0.1 2.5 2 0 0 2 2 2 1 WD40-like domain 2-oxogl_dehyd_N PF16078.5 GAM26074.1 - 0.067 12.8 0.4 0.16 11.5 0.4 1.7 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus MOR2-PAG1_C PF14225.6 GAM26074.1 - 0.072 12.9 3.2 0.3 10.9 0.3 3.0 3 0 0 3 3 3 0 Cell morphogenesis C-terminal SNARE PF05739.19 GAM26075.1 - 3.2e-10 39.8 1.5 6.6e-10 38.8 1.5 1.4 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 GAM26075.1 - 0.00097 18.9 5.0 0.0012 18.6 5.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Prominin PF05478.11 GAM26075.1 - 0.073 11.0 6.2 0.1 10.5 6.2 1.5 1 1 0 1 1 1 0 Prominin FNIP PF05725.12 GAM26076.1 - 2.5e-104 341.2 9.6 1.2e-11 44.6 0.0 11.3 4 3 10 15 15 15 14 FNIP Repeat LRR_5 PF13306.6 GAM26076.1 - 0.017 15.1 0.0 7.3 6.6 0.0 2.7 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) TPR_12 PF13424.6 GAM26077.1 - 1.4e-76 252.8 14.2 8.8e-15 54.8 0.0 7.9 5 2 1 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 GAM26077.1 - 3.9e-47 156.9 3.6 1.8e-06 27.6 0.0 11.6 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 GAM26077.1 - 2.5e-37 125.2 45.7 0.00093 18.9 0.0 11.7 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 GAM26077.1 - 6.5e-33 110.2 34.9 0.0044 17.0 1.0 11.9 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 GAM26077.1 - 1.2e-26 90.7 46.1 0.0016 18.5 1.7 11.4 10 1 1 11 11 10 9 Tetratricopeptide repeat TPR_7 PF13176.6 GAM26077.1 - 3.6e-24 83.0 13.4 0.0022 17.9 0.0 10.0 10 1 1 11 11 9 4 Tetratricopeptide repeat DUF4062 PF13271.6 GAM26077.1 - 2.6e-15 56.6 0.0 1.2e-14 54.4 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) BRCT_2 PF16589.5 GAM26077.1 - 1.3e-13 51.1 1.1 7.1e-13 48.8 0.0 2.8 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain TPR_19 PF14559.6 GAM26077.1 - 4.5e-11 43.1 9.6 0.18 12.3 0.0 7.4 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM26077.1 - 5.4e-11 42.5 0.5 0.00028 20.4 0.0 4.8 1 1 3 4 4 4 3 MalT-like TPR region BRCT PF00533.26 GAM26077.1 - 5.1e-08 33.2 0.0 1.7e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain TPR_16 PF13432.6 GAM26077.1 - 2.3e-06 28.1 10.7 2.2 9.0 0.0 8.3 8 1 2 10 10 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM26077.1 - 3.6e-06 27.0 6.9 14 6.4 0.0 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM26077.1 - 8.7e-06 25.9 12.4 1 9.7 0.2 6.4 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.12 GAM26077.1 - 3.1e-05 24.0 0.0 0.0001 22.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain TPR_11 PF13414.6 GAM26077.1 - 3.7e-05 23.3 32.8 0.57 9.9 0.9 10.2 9 2 2 11 11 11 1 TPR repeat TPR_6 PF13174.6 GAM26077.1 - 0.00011 22.7 17.2 27 5.7 0.5 9.4 9 1 0 9 9 7 0 Tetratricopeptide repeat DUF4404 PF14357.6 GAM26077.1 - 0.032 14.9 0.5 22 5.8 0.0 4.2 3 2 2 5 5 3 0 Domain of unknown function (DUF4404) SPO22 PF08631.10 GAM26077.1 - 0.065 12.7 0.0 0.065 12.7 0.0 4.9 3 2 2 5 5 5 0 Meiosis protein SPO22/ZIP4 like ANAPC5 PF12862.7 GAM26077.1 - 0.18 11.9 7.2 68 3.6 5.4 4.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 14-3-3 PF00244.20 GAM26077.1 - 0.43 10.0 15.5 2.7 7.5 0.1 5.2 4 2 1 5 5 5 0 14-3-3 protein DUF5113 PF17140.4 GAM26077.1 - 0.43 10.4 15.4 5.2 6.9 0.1 6.1 4 2 3 7 7 7 0 Domain of unknown function (DUF5113) MIT PF04212.18 GAM26077.1 - 0.49 10.5 23.6 0.44 10.6 1.0 7.6 8 1 1 9 9 8 0 MIT (microtubule interacting and transport) domain LRR_6 PF13516.6 GAM26078.1 - 3e-08 33.1 18.8 0.054 13.6 0.0 8.3 8 0 0 8 8 8 3 Leucine Rich repeat LRR_8 PF13855.6 GAM26078.1 - 2.7e-06 27.1 10.4 0.086 12.6 0.4 7.4 5 2 2 7 7 7 3 Leucine rich repeat LRR_4 PF12799.7 GAM26078.1 - 0.0054 17.1 15.9 9.6 6.8 0.0 7.3 7 1 1 8 8 8 2 Leucine Rich repeats (2 copies) Viral_alk_exo PF01771.17 GAM26078.1 - 0.013 14.4 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Viral alkaline exonuclease LRR_1 PF00560.33 GAM26078.1 - 0.028 14.9 12.5 28 5.8 0.0 7.7 9 0 0 9 9 9 0 Leucine Rich Repeat Sugarporin_N PF11471.8 GAM26079.1 - 0.0023 17.8 0.1 0.0036 17.2 0.1 1.3 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension ABC_tran_CTD PF16326.5 GAM26079.1 - 0.036 14.3 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF4606 PF15379.6 GAM26080.1 - 0.29 11.4 0.1 0.29 11.4 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4606) Occludin_ELL PF07303.13 GAM26081.1 - 0.0003 21.4 12.3 0.0003 21.4 12.3 2.8 3 0 0 3 3 3 1 Occludin homology domain Vac_ImportDeg PF09783.9 GAM26082.1 - 1.7e-42 145.0 4.8 2e-42 144.8 4.8 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein FNIP PF05725.12 GAM26083.1 - 1.1e-78 259.2 36.0 1.8e-13 50.4 0.2 9.3 3 3 7 12 12 12 11 FNIP Repeat DUF1769 PF08588.10 GAM26083.1 - 0.00016 21.8 2.0 7 6.9 0.0 5.0 3 2 3 6 6 6 3 Protein of unknown function (DUF1769) tRNA-synt_2b PF00587.25 GAM26084.1 - 7.4e-38 130.3 0.0 1.2e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAM26084.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Anticodon binding domain RhoGEF PF00621.20 GAM26085.1 - 3.1e-48 164.4 1.8 9.2e-48 162.9 1.8 1.8 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAM26085.1 - 0.00028 21.3 0.4 0.00095 19.6 0.4 1.9 1 0 0 1 1 1 1 PH domain Asp-B-Hydro_N PF05279.11 GAM26085.1 - 4.5 7.3 41.9 0.58 10.2 35.6 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Pkinase_Tyr PF07714.17 GAM26086.1 - 3.3e-64 216.7 0.0 4.7e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SPRY PF00622.28 GAM26086.1 - 1.1e-56 190.1 7.9 8e-21 74.4 0.6 3.7 3 0 0 3 3 3 3 SPRY domain Pkinase PF00069.25 GAM26086.1 - 4.6e-45 154.0 0.0 7.7e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.17 GAM26086.1 - 2.8e-12 46.6 0.0 6.9e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAM26086.1 - 1.3e-09 38.3 0.0 3.2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 GAM26086.1 - 0.0011 17.9 0.0 0.0022 16.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Neuralized PF07177.12 GAM26086.1 - 0.0031 17.5 0.0 3.7 7.5 0.0 4.0 3 2 0 3 3 3 1 Neuralized Myb_DNA-bind_7 PF15963.5 GAM26088.1 - 2e-26 91.7 4.4 2e-26 91.7 4.4 2.7 3 1 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 GAM26088.1 - 5.8e-05 23.2 0.3 0.00014 21.9 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM26088.1 - 0.011 15.9 0.2 0.011 15.9 0.2 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain BrnT_toxin PF04365.13 GAM26088.1 - 0.14 12.5 3.2 0.56 10.6 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system AAA_33 PF13671.6 GAM26089.1 - 5.5e-16 59.0 0.1 1.8e-13 50.9 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM26089.1 - 0.16 12.5 0.5 4.1 8.0 0.0 3.2 3 1 0 3 3 3 0 AAA domain Glyco_hydro_25 PF01183.20 GAM26090.1 - 5e-13 49.6 0.1 5.9e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 E1-E2_ATPase PF00122.20 GAM26091.1 - 4e-36 124.2 0.1 4e-36 124.2 0.1 4.3 6 0 0 6 6 6 2 E1-E2 ATPase Hydrolase PF00702.26 GAM26091.1 - 1.7e-18 67.7 0.0 1.2e-12 48.5 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 GAM26091.1 - 2.6e-13 50.2 0.5 5.8e-13 49.0 0.5 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 GAM26091.1 - 0.016 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Peptidase_C97 PF05903.14 GAM26092.1 - 3.5e-42 143.8 0.1 8.4e-42 142.5 0.1 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 GAM26092.1 - 1.5e-35 122.8 0.2 2.4e-35 122.1 0.2 1.3 1 0 0 1 1 1 1 PUL domain LRAT PF04970.13 GAM26092.1 - 0.028 14.7 2.2 0.061 13.6 0.1 2.4 2 0 0 2 2 2 0 Lecithin retinol acyltransferase PRP21_like_P PF12230.8 GAM26092.1 - 0.08 12.8 0.3 0.13 12.2 0.3 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C3Hc3H PF13891.6 GAM26092.1 - 0.12 12.8 0.4 0.63 10.5 0.2 2.2 2 0 0 2 2 2 0 Potential DNA-binding domain FNIP PF05725.12 GAM26093.1 - 5.3e-101 330.6 47.3 1.2e-14 54.2 0.3 10.0 3 2 8 13 13 13 13 FNIP Repeat SAC3_GANP PF03399.16 GAM26094.1 - 4.1e-11 42.8 3.0 2e-08 34.0 1.3 3.2 1 1 1 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GAM26094.1 - 0.019 15.0 0.1 0.17 11.8 0.0 2.4 2 1 0 2 2 2 0 CSN8/PSMD8/EIF3K family Cohesin_HEAT PF12765.7 GAM26094.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Oxysterol_BP PF01237.18 GAM26095.1 - 1.8e-61 208.1 5.4 3e-59 200.7 5.4 2.3 1 1 0 1 1 1 1 Oxysterol-binding protein UIM PF02809.20 GAM26096.1 - 0.091 12.7 0.2 0.27 11.2 0.2 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif PIP5K PF01504.18 GAM26099.1 - 5.3e-66 222.6 20.4 1.2e-43 149.3 4.2 2.8 3 0 0 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase PH PF00169.29 GAM26099.1 - 1.2e-14 54.6 1.0 5.8e-14 52.5 0.1 2.7 2 1 0 2 2 2 1 PH domain PH_11 PF15413.6 GAM26099.1 - 7.5e-06 26.3 6.4 0.00014 22.3 0.4 4.2 2 2 1 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 GAM26099.1 - 0.0001 22.5 0.0 0.00031 21.0 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Myb_DNA-binding PF00249.31 GAM26100.1 - 2.5e-30 104.4 8.7 1.3e-13 50.9 0.9 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM26100.1 - 6.6e-25 87.1 5.9 3.7e-13 49.5 0.1 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain DUF1981 PF09324.10 GAM26100.1 - 0.0023 17.7 0.2 0.0058 16.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) SLIDE PF09111.10 GAM26100.1 - 0.0037 17.3 1.1 1.7 8.7 0.0 3.1 3 0 0 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 GAM26100.1 - 0.0064 16.8 12.9 0.069 13.5 0.3 4.0 3 1 0 4 4 4 2 Myb/SANT-like DNA-binding domain MNE1 PF13762.6 GAM26100.1 - 0.0071 16.3 0.4 0.017 15.1 0.4 1.6 1 0 0 1 1 1 1 Mitochondrial splicing apparatus component SANT_DAMP1_like PF16282.5 GAM26100.1 - 0.008 16.3 2.4 3.5 7.9 0.0 3.3 3 1 1 4 4 4 2 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 GAM26100.1 - 0.96 9.8 5.2 1.6 9.1 0.1 3.3 3 1 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RhoGEF PF00621.20 GAM26101.1 - 7.7e-42 143.6 5.7 7.7e-42 143.6 5.7 3.7 2 1 0 2 2 2 1 RhoGEF domain IQ PF00612.27 GAM26101.1 - 0.0035 17.0 1.1 0.0087 15.8 1.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH PF00169.29 GAM26101.1 - 0.0061 17.0 0.1 0.018 15.5 0.1 1.8 1 0 0 1 1 1 1 PH domain FA_desaturase PF00487.24 GAM26101.1 - 0.34 10.7 2.8 9.3 6.0 4.3 2.1 2 0 0 2 2 2 0 Fatty acid desaturase zf-UBR PF02207.20 GAM26102.1 - 2.8e-15 56.2 20.4 1.1e-14 54.3 20.4 2.1 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) SSP160 PF06933.11 GAM26102.1 - 1.1 7.3 7.1 1.7 6.8 7.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CNDH2_C PF16858.5 GAM26102.1 - 1.7 8.5 19.2 2.1 8.2 1.1 3.0 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Arginase PF00491.21 GAM26104.1 - 9.7e-54 182.8 0.2 1.1e-53 182.6 0.2 1.0 1 0 0 1 1 1 1 Arginase family FMO-like PF00743.19 GAM26105.1 - 2.4e-21 75.8 0.1 1.2e-20 73.5 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAM26105.1 - 2.2e-12 46.8 0.0 2e-10 40.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAM26105.1 - 2.8e-09 36.6 0.0 3e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM26105.1 - 1.1e-08 35.2 0.0 2.9e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAM26105.1 - 7e-08 32.1 0.0 3.6e-06 26.5 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM26105.1 - 0.002 18.1 0.0 1.7 8.6 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 GAM26105.1 - 0.019 14.6 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 GAM26105.1 - 0.19 10.8 0.1 4.1 6.4 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A BioW PF03744.13 GAM26108.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase FNIP PF05725.12 GAM26109.1 - 6.1e-48 160.7 8.2 3e-15 56.1 1.1 4.3 2 1 2 4 4 4 4 FNIP Repeat Peptidase_M16_M PF16187.5 GAM26110.1 - 9.2e-50 169.5 2.5 9.2e-50 169.5 2.5 1.7 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 GAM26110.1 - 1.4e-37 128.9 4.1 1.4e-36 125.8 0.2 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAM26110.1 - 3e-26 92.5 3.5 1e-12 48.5 0.0 4.6 5 0 0 5 5 5 2 Peptidase M16 inactive domain Dopey_N PF04118.14 GAM26111.1 - 7.3e-85 284.8 1.5 7.3e-85 284.8 1.5 4.3 6 0 0 6 6 6 1 Dopey, N-terminal DUF1981 PF09324.10 GAM26111.1 - 0.052 13.4 0.4 14 5.6 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) DNApol3-delta_C PF09115.10 GAM26111.1 - 0.96 10.0 6.7 5.9 7.4 0.1 3.8 3 0 0 3 3 3 0 DNA polymerase III, delta subunit, C terminal G8 PF10162.9 GAM26112.1 - 4.6e-24 84.9 0.0 1.7e-23 83.0 0.0 2.1 1 0 0 1 1 1 1 G8 domain CBM_4_9 PF02018.17 GAM26112.1 - 0.0052 17.1 0.0 0.022 15.0 0.0 2.1 1 0 0 1 1 1 1 Carbohydrate binding domain FNIP PF05725.12 GAM26113.1 - 2.4e-31 107.6 0.6 9.3e-12 44.9 0.2 5.8 5 0 0 5 5 5 5 FNIP Repeat bZIP_1 PF00170.21 GAM26113.1 - 0.075 13.1 1.4 0.1 12.7 0.3 1.8 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 GAM26113.1 - 0.51 10.5 2.7 4.2 7.5 0.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper FNIP PF05725.12 GAM26114.1 - 1.8e-30 104.9 14.3 7.3e-13 48.5 2.7 4.3 3 1 0 4 4 4 4 FNIP Repeat Gal4_dimer PF03902.13 GAM26114.1 - 0.18 12.0 0.1 0.6 10.3 0.0 1.8 2 0 0 2 2 2 0 Gal4-like dimerisation domain NAP PF00956.18 GAM26116.1 - 9.8e-48 162.7 0.5 1.3e-47 162.3 0.5 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) FliX PF10768.9 GAM26116.1 - 0.099 13.2 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Class II flagellar assembly regulator TraK PF06586.11 GAM26116.1 - 0.1 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 TraK protein Cation_efflux PF01545.21 GAM26117.1 - 2.2e-41 141.8 12.6 2.9e-41 141.4 12.6 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 GAM26118.1 - 1.3e-37 129.7 9.1 4.3e-37 128.1 8.8 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter PPP4R2 PF09184.11 GAM26118.1 - 0.029 14.0 2.0 0.043 13.4 2.0 1.2 1 0 0 1 1 1 0 PPP4R2 Dicty_REP PF05086.12 GAM26118.1 - 0.11 10.4 0.8 0.16 9.9 0.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.25 GAM26119.1 - 1.1e-64 218.4 0.0 8.1e-64 215.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26119.1 - 6.3e-30 104.3 0.0 1e-22 80.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase PH PF00169.29 GAM26119.1 - 4.9e-20 72.0 2.2 1.7e-19 70.3 0.1 3.1 3 0 0 3 3 3 1 PH domain PX PF00787.24 GAM26119.1 - 1.5e-18 66.8 2.2 2.5e-18 66.1 0.4 2.4 2 0 0 2 2 2 1 PX domain Kinase-like PF14531.6 GAM26119.1 - 1.2e-05 24.8 0.1 0.00088 18.7 0.0 2.9 3 0 0 3 3 3 1 Kinase-like PH_8 PF15409.6 GAM26119.1 - 4e-05 23.8 0.0 0.00011 22.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 GAM26119.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM26119.1 - 0.008 15.2 0.1 0.008 15.2 0.1 4.0 3 2 1 4 4 2 1 Haspin like kinase domain PH_3 PF14593.6 GAM26119.1 - 0.02 15.0 0.2 0.096 12.8 0.1 2.2 2 0 0 2 2 2 0 PH domain Seadorna_VP7 PF07387.11 GAM26119.1 - 0.069 12.2 0.1 0.19 10.8 0.1 1.7 1 0 0 1 1 1 0 Seadornavirus VP7 PH_11 PF15413.6 GAM26119.1 - 3.4 8.1 8.4 0.38 11.2 1.3 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain ABC_transp_aux PF09822.9 GAM26120.1 - 0.3 10.5 2.8 0.31 10.5 0.6 2.1 2 1 0 2 2 2 0 ABC-type uncharacterized transport system LisH PF08513.11 GAM26120.1 - 8 6.6 5.4 8.1 6.6 1.4 2.8 3 0 0 3 3 3 0 LisH GtrA PF04138.14 GAM26121.1 - 0.0074 16.5 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 GtrA-like protein Sec7_N PF12783.7 GAM26122.1 - 0.035 14.0 3.5 0.91 9.4 0.2 3.2 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Aldo_ket_red PF00248.21 GAM26123.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Aldo/keto reductase family zf-C2H2_4 PF13894.6 GAM26124.1 - 1.6 9.7 13.6 0.48 11.4 0.7 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4497 PF14924.6 GAM26124.1 - 4 8.0 6.7 1.6 9.2 0.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4497) CorA PF01544.18 GAM26124.1 - 6.2 6.0 9.1 3.2 7.0 0.5 3.0 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein DUF4838 PF16126.5 GAM26127.1 - 0.021 14.2 0.1 0.046 13.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) S-AdoMet_synt_M PF02772.16 GAM26127.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, central domain DUF1548 PF07579.11 GAM26127.1 - 0.09 13.1 0.1 0.28 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Remorin_C PF03763.13 GAM26130.1 - 0.099 12.5 3.2 0.2 11.6 0.5 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region HAUS-augmin3 PF14932.6 GAM26131.1 - 0.048 13.2 2.5 0.057 13.0 2.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FliH PF02108.16 GAM26132.1 - 0.019 15.0 0.8 0.71 9.9 0.1 3.5 3 0 0 3 3 3 0 Flagellar assembly protein FliH Sod_Ni PF09055.11 GAM26132.1 - 0.045 14.3 4.1 0.17 12.5 1.2 2.8 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase Abhydrolase_6 PF12697.7 GAM26133.1 - 1.1e-17 65.3 0.0 1.5e-17 64.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 GAM26133.1 - 3.3e-06 27.0 0.1 5.4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM26133.1 - 0.00014 21.2 0.8 0.0028 17.0 0.8 2.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 GAM26133.1 - 0.00027 20.9 0.1 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_1 PF00561.20 GAM26133.1 - 0.003 17.3 2.9 0.035 13.8 1.4 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold CW_7 PF08230.11 GAM26133.1 - 0.09 12.5 0.5 0.32 10.8 0.5 2.0 1 1 0 1 1 1 0 CW_7 repeat Peptidase_M41 PF01434.18 GAM26134.1 - 4.7e-56 189.7 2.8 9.3e-56 188.7 2.8 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAM26134.1 - 1.8e-43 148.1 0.6 3e-42 144.2 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM26134.1 - 3.6e-08 33.1 0.0 7.8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 GAM26134.1 - 6.9e-06 26.6 0.3 0.0002 21.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM26134.1 - 9.3e-06 26.1 0.1 0.0017 18.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 GAM26134.1 - 9.6e-06 25.6 0.7 7.8e-05 22.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM26134.1 - 3.8e-05 24.0 0.0 0.012 15.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAM26134.1 - 0.0001 22.1 0.0 0.0005 19.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 GAM26134.1 - 0.00017 21.6 0.3 0.011 15.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 GAM26134.1 - 0.00022 21.0 0.0 0.00057 19.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 GAM26134.1 - 0.00034 20.8 0.0 0.002 18.3 0.0 2.4 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 GAM26134.1 - 0.00049 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 GAM26134.1 - 0.0021 17.8 0.4 0.052 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAM26134.1 - 0.0027 17.9 0.0 0.0087 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAM26134.1 - 0.0046 16.4 0.2 0.014 14.8 0.2 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAM26134.1 - 0.0072 15.9 0.1 0.025 14.1 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAM26134.1 - 0.0086 15.4 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 GAM26134.1 - 0.015 15.5 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM26134.1 - 0.016 15.7 1.1 0.099 13.2 0.0 2.6 2 1 1 3 3 3 0 ABC transporter Sigma54_activat PF00158.26 GAM26134.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 GAM26134.1 - 0.043 14.2 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Exosortase_EpsH PF09721.10 GAM26134.1 - 0.051 13.1 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) AAA_25 PF13481.6 GAM26134.1 - 0.065 12.8 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-CSL PF05207.13 GAM26135.1 - 4.8e-22 77.5 1.4 4.8e-22 77.5 1.4 1.5 2 0 0 2 2 2 1 CSL zinc finger zinc_ribbon_4 PF13717.6 GAM26135.1 - 0.022 14.7 0.4 0.042 13.8 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_7 PF02591.15 GAM26135.1 - 0.037 14.2 0.1 0.081 13.1 0.1 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain zf-RING_4 PF14570.6 GAM26135.1 - 0.074 12.9 2.5 0.17 11.7 2.5 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain NatB_MDM20 PF09797.9 GAM26136.1 - 1.1e-76 258.3 5.3 1.1e-76 258.3 5.3 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 GAM26136.1 - 1.1e-09 38.7 4.9 0.0017 18.9 0.0 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM26136.1 - 1.2e-06 28.6 10.1 0.00057 20.1 1.8 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAM26136.1 - 2.8e-06 27.0 0.4 0.59 10.4 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM26136.1 - 0.0006 19.5 5.5 0.51 10.3 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM26136.1 - 0.002 18.8 0.0 8.1 7.6 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM26136.1 - 0.023 15.0 5.0 0.34 11.2 0.0 4.6 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM26136.1 - 0.054 14.1 0.1 14 6.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat KinB_sensor PF16767.5 GAM26136.1 - 0.11 13.0 6.2 0.48 10.9 0.1 3.5 2 1 1 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB PPR PF01535.20 GAM26136.1 - 0.18 12.1 1.7 36 4.9 0.1 3.8 4 0 0 4 4 4 0 PPR repeat TPR_8 PF13181.6 GAM26136.1 - 0.34 11.2 4.8 6.7 7.2 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5367 PF17329.2 GAM26137.1 - 0.88 9.7 8.0 0.14 12.3 0.8 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5367) Amastin PF07344.11 GAM26137.1 - 1.3 8.8 13.6 0.082 12.8 6.1 2.5 2 1 1 3 3 3 0 Amastin surface glycoprotein Pox_A9 PF04835.12 GAM26137.1 - 3 8.1 6.7 0.88 9.8 0.4 2.6 2 0 0 2 2 2 0 A9 protein conserved region SYS1 PF09801.9 GAM26138.1 - 2.1e-46 157.6 10.7 2.6e-46 157.4 10.7 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Rrp15p PF07890.12 GAM26139.1 - 1.1e-16 61.3 11.3 1.1e-16 61.3 11.3 3.0 1 1 0 2 2 2 1 Rrp15p Hairpins PF04877.12 GAM26139.1 - 0.092 12.4 3.7 0.17 11.5 3.7 1.3 1 0 0 1 1 1 0 HrpZ Glyco_hydro_1 PF00232.18 GAM26140.1 - 0.042 12.3 6.3 0.084 11.3 6.3 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Coatomer_WDAD PF04053.14 GAM26141.1 - 4e-160 533.7 0.6 9.8e-160 532.4 0.1 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 GAM26141.1 - 3.2e-38 129.0 4.7 2.7e-08 34.3 0.1 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM26141.1 - 9.4e-07 29.1 0.4 3 8.2 0.0 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM26141.1 - 0.014 14.1 1.5 2.4 6.7 0.0 3.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAM26141.1 - 0.039 12.7 0.1 36 2.9 0.0 3.6 3 1 1 4 4 4 0 Nup133 N terminal like Pkinase PF00069.25 GAM26142.1 - 6.8e-24 84.6 0.0 9.7e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26142.1 - 3.4e-13 49.5 0.0 6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM26142.1 - 1.3e-09 37.4 0.1 1.3e-09 37.4 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAM26142.1 - 0.012 15.5 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 GAM26142.1 - 0.098 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 GAM26142.1 - 0.33 10.3 1.9 0.29 10.4 0.2 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 GAM26143.1 - 8.9e-51 171.2 0.1 1e-50 171.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 GAM26144.1 - 1.9e-70 237.2 0.2 2.6e-70 236.8 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26144.1 - 4.4e-25 88.4 0.1 1.1e-24 87.2 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM26144.1 - 5.1e-08 32.6 0.0 1.1e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 GAM26144.1 - 5.6e-05 23.2 0.0 0.28 11.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GAM26144.1 - 6.8e-05 22.3 0.1 0.00011 21.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM26144.1 - 0.004 16.8 0.0 0.0082 15.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family DUF1168 PF06658.12 GAM26145.1 - 1.2e-28 99.6 22.1 1.4e-28 99.4 22.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) MMU163 PF17119.5 GAM26145.1 - 0.16 11.1 4.8 0.2 10.8 4.5 1.2 1 1 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF5446 PF17522.2 GAM26145.1 - 1.2 9.4 7.9 1.4 9.1 1.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5446) LMBR1 PF04791.16 GAM26145.1 - 1.9 7.3 2.6 1.7 7.5 2.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein BRF1 PF07741.13 GAM26145.1 - 3.6 8.0 17.5 7.6 6.9 17.3 1.8 1 1 0 1 1 1 0 Brf1-like TBP-binding domain TMPIT PF07851.13 GAM26145.1 - 8 5.6 5.6 9.8 5.3 5.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein AAA_11 PF13086.6 GAM26146.1 - 4.5e-61 206.9 0.0 4.5e-61 206.9 0.0 3.8 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 GAM26146.1 - 1.3e-54 184.9 2.4 2.1e-54 184.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain R3H PF01424.22 GAM26146.1 - 3.6e-14 52.5 0.5 1.3e-13 50.7 0.3 2.1 2 0 0 2 2 2 1 R3H domain AAA_30 PF13604.6 GAM26146.1 - 1.7e-10 40.9 0.0 7.4e-09 35.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM26146.1 - 3.2e-08 34.0 0.0 2.5e-07 31.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain zf-AN1 PF01428.16 GAM26146.1 - 1.4e-06 28.4 3.6 3.1e-06 27.2 3.6 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger AAA_16 PF13191.6 GAM26146.1 - 0.00019 21.9 0.0 0.00098 19.5 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 GAM26146.1 - 0.0015 17.9 0.0 0.0053 16.1 0.0 1.9 1 0 0 1 1 1 1 KaiC Viral_helicase1 PF01443.18 GAM26146.1 - 0.0024 17.7 8.7 0.69 9.6 0.0 3.9 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GAM26146.1 - 0.0059 16.9 0.8 0.036 14.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAM26146.1 - 0.02 14.5 0.0 0.02 14.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 GAM26146.1 - 0.023 15.1 1.2 0.096 13.1 1.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 GAM26146.1 - 0.051 14.1 0.1 0.051 14.1 0.1 2.9 2 2 1 3 3 3 0 ABC transporter Helicase_RecD PF05127.14 GAM26146.1 - 0.16 11.8 3.7 2.1 8.2 0.0 3.2 2 2 0 2 2 2 0 Helicase SSP160 PF06933.11 GAM26146.1 - 1.4 7.0 9.8 2.2 6.3 9.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BioY PF02632.14 GAM26147.1 - 0.00011 22.2 1.8 0.00016 21.7 1.8 1.1 1 0 0 1 1 1 1 BioY family MLANA PF14991.6 GAM26147.1 - 0.099 12.9 0.3 0.099 12.9 0.3 2.6 2 1 1 3 3 3 0 Protein melan-A DUF4064 PF13273.6 GAM26147.1 - 6.1 7.2 11.7 2.1 8.7 5.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) UBX PF00789.20 GAM26148.1 - 5.9e-10 39.2 0.0 1.4e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 GAM26148.1 - 0.00019 21.6 0.0 0.0004 20.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Rrn6 PF10214.9 GAM26148.1 - 0.009 14.6 1.4 0.011 14.3 1.4 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF5401 PF17380.2 GAM26148.1 - 0.18 9.8 23.1 0.25 9.4 23.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Asp-B-Hydro_N PF05279.11 GAM26148.1 - 0.26 11.3 13.2 0.36 10.9 13.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SWI-SNF_Ssr4 PF08549.10 GAM26148.1 - 1.2 7.7 10.2 1.6 7.3 10.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Presenilin PF01080.17 GAM26148.1 - 6.3 5.5 6.5 8.1 5.1 6.5 1.1 1 0 0 1 1 1 0 Presenilin AAA_23 PF13476.6 GAM26148.1 - 6.4 7.2 10.7 9.5 6.7 10.7 1.3 1 0 0 1 1 1 0 AAA domain FNIP PF05725.12 GAM26150.1 - 2.8e-78 257.9 38.8 1.9e-14 53.5 1.2 9.5 5 3 5 10 10 10 10 FNIP Repeat DUF3281 PF11685.8 GAM26150.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3281) LRR_1 PF00560.33 GAM26150.1 - 5.7 7.9 10.4 3.9 8.4 0.2 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat Ank_4 PF13637.6 GAM26151.1 - 1.3e-40 137.2 16.4 9.4e-07 29.3 0.0 10.4 6 2 7 13 13 13 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM26151.1 - 5.8e-39 131.6 20.8 0.00028 21.1 0.1 15.0 3 2 13 16 16 16 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM26151.1 - 1.4e-37 128.1 22.3 1.9e-07 31.6 0.3 7.3 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM26151.1 - 2.7e-19 67.2 7.9 1.6 9.6 0.0 14.6 13 3 3 16 16 16 2 Ankyrin repeat DUF5049 PF16468.5 GAM26151.1 - 1.6e-11 43.9 5.4 11 6.0 0.0 10.7 4 3 8 12 12 12 3 Domain of unknown function (DUF5049) Ank PF00023.30 GAM26151.1 - 4.9e-09 36.2 2.9 42 4.8 0.1 10.5 6 3 2 8 8 8 0 Ankyrin repeat AhpC-TSA PF00578.21 GAM26151.1 - 0.002 18.1 0.1 35 4.3 0.0 5.0 4 3 3 7 7 7 0 AhpC/TSA family VbhA PF18495.1 GAM26151.1 - 0.0043 16.9 2.0 30 4.6 0.0 5.8 5 1 1 6 6 6 0 Antitoxin VbhA 4HBT_2 PF13279.6 GAM26151.1 - 0.025 15.1 1.7 12 6.4 0.0 4.0 2 2 1 3 3 3 0 Thioesterase-like superfamily DUF1707 PF08044.11 GAM26151.1 - 0.054 13.6 5.4 31 4.7 0.1 6.0 9 0 0 9 9 9 0 Domain of unknown function (DUF1707) DUF249 PF03158.13 GAM26151.1 - 0.09 12.5 0.0 8.6 6.0 0.0 3.8 3 2 2 5 5 5 0 Multigene family 530 protein Syja_N PF02383.18 GAM26152.1 - 8.8e-45 153.4 0.6 8.8e-45 153.4 0.6 2.1 2 0 0 2 2 2 1 SacI homology domain FYVE PF01363.21 GAM26152.1 - 0.00089 19.3 8.8 0.002 18.2 8.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger Zn_Tnp_IS91 PF14319.6 GAM26152.1 - 0.062 13.3 7.3 0.19 11.8 7.3 1.8 1 0 0 1 1 1 0 Transposase zinc-binding domain FYVE_2 PF02318.16 GAM26152.1 - 0.7 10.1 7.0 1.6 9.0 7.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DAGK_cat PF00781.24 GAM26153.1 - 1.3e-30 105.6 0.0 2.2e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 GAM26153.1 - 0.00042 19.6 0.0 0.00082 18.7 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase zf-Nse PF11789.8 GAM26154.1 - 2.2e-20 72.2 0.5 3.8e-20 71.5 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 GAM26154.1 - 6.2e-06 26.1 0.2 1.2e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.20 GAM26154.1 - 1.1e-05 25.1 0.2 2.2e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Rtf2 PF04641.12 GAM26154.1 - 0.0016 17.9 2.7 0.0016 17.9 2.7 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 GAM26154.1 - 0.0033 17.2 0.1 0.0081 16.0 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM26154.1 - 0.0083 16.0 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAM26154.1 - 0.052 13.7 0.2 0.15 12.3 0.0 1.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GAM26154.1 - 0.077 13.4 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 GAM26154.1 - 0.11 12.8 0.1 0.27 11.6 0.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain HTH_43 PF09904.9 GAM26154.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Asparaginase_2 PF01112.18 GAM26154.1 - 0.18 10.8 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Asparaginase Med21 PF11221.8 GAM26155.1 - 4.7e-25 88.5 4.1 6.9e-25 88.0 4.1 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF4868 PF16162.5 GAM26155.1 - 0.021 14.8 0.3 0.023 14.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4868) Cauli_AT PF03233.13 GAM26155.1 - 0.096 12.6 3.0 1.8 8.5 0.1 2.1 2 0 0 2 2 2 0 Aphid transmission protein RHH_3 PF12651.7 GAM26155.1 - 0.12 12.4 1.6 0.19 11.7 0.1 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix domain LMBR1 PF04791.16 GAM26155.1 - 0.77 8.6 4.3 0.98 8.3 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein adh_short PF00106.25 GAM26156.1 - 8.9e-43 146.0 0.2 1.2e-42 145.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM26156.1 - 5.2e-26 91.6 0.0 6.8e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM26156.1 - 1e-07 32.1 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM26156.1 - 0.0091 15.5 0.1 0.052 13.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM26156.1 - 0.0095 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAM26156.1 - 0.013 14.6 0.2 0.022 13.9 0.2 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 GAM26156.1 - 0.05 13.0 0.0 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) CTC1 PF15489.6 GAM26158.1 - 0.0058 14.2 0.0 0.0084 13.7 0.0 1.2 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 T2SSC PF11356.8 GAM26158.1 - 0.17 11.7 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Type II secretion system protein C p450 PF00067.22 GAM26160.1 - 1.3e-86 291.2 0.1 1.4e-86 291.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.22 GAM26161.1 - 1.9e-89 300.5 1.6 2.5e-89 300.1 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAM26161.1 - 1.3e-13 51.7 2.0 9.7e-13 49.0 2.0 2.3 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAM26161.1 - 0.002 18.9 0.0 0.0038 18.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Ribosomal_L21p PF00829.21 GAM26162.1 - 9.3e-30 102.9 1.3 9.3e-30 102.9 1.3 1.8 1 1 1 2 2 2 1 Ribosomal prokaryotic L21 protein Mucin PF01456.17 GAM26162.1 - 0.015 15.3 13.8 0.025 14.6 13.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4293 PF14126.6 GAM26162.1 - 0.07 13.4 0.1 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) TMEM154 PF15102.6 GAM26162.1 - 0.13 12.2 4.5 0.23 11.3 4.5 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF3439 PF11921.8 GAM26162.1 - 0.24 11.4 8.2 0.49 10.4 8.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FSA_C PF10479.9 GAM26162.1 - 1.2 7.2 14.1 1.5 6.8 14.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Fip1 PF05182.13 GAM26163.1 - 7.2e-24 83.0 1.9 1.3e-23 82.2 1.9 1.4 1 0 0 1 1 1 1 Fip1 motif DUF4266 PF14086.6 GAM26163.1 - 0.12 13.4 3.1 0.52 11.3 3.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) GlcNAc PF11397.8 GAM26164.1 - 2.1e-67 228.1 0.0 2.7e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) TGT PF01702.18 GAM26165.1 - 4.3e-81 272.8 0.0 6.4e-66 222.9 0.0 2.0 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase Kelch_4 PF13418.6 GAM26166.1 - 5e-34 116.1 8.6 2.6e-08 33.7 0.2 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM26166.1 - 5.6e-34 115.6 6.0 1.5e-09 37.6 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 GAM26166.1 - 2.8e-31 107.2 22.9 8e-09 35.6 0.1 8.5 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM26166.1 - 3.3e-30 103.4 0.4 2e-08 33.6 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 GAM26166.1 - 2.6e-29 100.5 6.8 3.8e-08 33.3 0.1 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAM26166.1 - 7.4e-23 79.6 4.2 0.0024 17.8 0.0 6.8 6 0 0 6 6 6 5 Kelch motif Trypan_PARP PF05887.11 GAM26166.1 - 0.33 10.9 11.6 0.94 9.5 11.6 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TRAP_alpha PF03896.16 GAM26166.1 - 3.1 6.9 7.8 5.7 6.1 7.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RhoGAP PF00620.27 GAM26167.1 - 6.4e-25 87.7 0.1 8.8e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain GvpK PF05121.12 GAM26167.1 - 0.14 12.2 0.9 0.36 10.9 0.2 1.9 3 0 0 3 3 3 0 Gas vesicle protein K ASH PF15780.5 GAM26167.1 - 0.25 11.6 2.1 4.7 7.5 1.1 2.5 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MMR_HSR1_Xtn PF16897.5 GAM26168.1 - 1.9e-41 140.3 0.3 3.3e-41 139.6 0.3 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 GAM26168.1 - 1.3e-21 76.4 0.1 2.5e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 GAM26168.1 - 1.8e-20 73.1 0.0 4.3e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM26168.1 - 1.1e-10 41.3 0.0 2.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAM26168.1 - 0.0028 17.7 0.4 1.6 8.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 GAM26168.1 - 0.0064 15.5 0.2 0.016 14.2 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 GAM26168.1 - 0.11 11.9 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit VKG_Carbox PF05090.14 GAM26169.1 - 0.00011 21.2 10.8 0.00022 20.2 10.8 1.5 1 1 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase WD40 PF00400.32 GAM26170.1 - 7e-57 188.1 20.4 2.3e-09 37.7 1.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM26170.1 - 6.7e-15 55.2 0.4 0.0087 16.3 0.0 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM26170.1 - 2.5e-06 26.5 4.1 1.6 7.3 0.0 4.9 2 2 1 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 GAM26170.1 - 0.00036 20.0 0.0 1.1 8.5 0.0 3.0 1 1 2 3 3 3 2 WD40-like domain eIF2A PF08662.11 GAM26170.1 - 0.00036 20.5 0.1 0.015 15.2 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAM26170.1 - 0.00039 19.5 0.0 3.8 6.4 0.0 4.6 2 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAM26170.1 - 0.0015 18.4 0.4 0.62 10.1 0.1 3.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat RhoGAP PF00620.27 GAM26171.1 - 4.5e-27 94.7 2.5 1.3e-16 60.8 0.1 3.1 1 1 1 2 2 2 2 RhoGAP domain Ca_bind_SSO6904 PF18249.1 GAM26171.1 - 0.13 12.6 1.1 0.42 11.0 0.3 2.3 2 0 0 2 2 2 0 Calcium binding protein SSO6904 GDP_Man_Dehyd PF16363.5 GAM26172.1 - 4e-59 200.7 0.0 4.7e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAM26172.1 - 2e-52 178.1 0.0 2.4e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAM26172.1 - 2.2e-14 53.3 0.0 5.3e-13 48.8 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAM26172.1 - 2.3e-12 46.5 0.0 8.5e-12 44.6 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAM26172.1 - 2.1e-09 36.9 0.0 3.2e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 GAM26172.1 - 2.9e-08 33.8 0.0 5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 GAM26172.1 - 2.1e-06 27.3 0.0 3.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 GAM26172.1 - 2e-05 23.9 0.0 0.0074 15.5 0.0 3.1 2 1 0 2 2 2 1 Male sterility protein NmrA PF05368.13 GAM26172.1 - 0.014 14.9 0.3 2.3 7.7 0.1 2.3 2 1 0 2 2 2 0 NmrA-like family DALR_1 PF05746.15 GAM26173.1 - 2.2e-08 34.3 0.2 2.1e-07 31.1 0.2 2.0 1 1 0 1 1 1 1 DALR anticodon binding domain FNIP PF05725.12 GAM26174.1 - 1.7e-79 261.7 29.8 1.1e-12 47.9 0.2 10.1 6 2 2 10 10 10 10 FNIP Repeat FNIP PF05725.12 GAM26175.1 - 4.5e-79 260.4 22.2 1.2e-13 51.0 0.0 8.1 4 1 5 9 9 9 9 FNIP Repeat Myb_DNA-binding PF00249.31 GAM26175.1 - 1.3e-10 41.3 0.1 2.5e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain PseudoU_synth_1 PF01416.20 GAM26175.1 - 0.015 15.8 0.0 0.07 13.6 0.0 2.2 1 0 0 1 1 1 0 tRNA pseudouridine synthase Myb_DNA-bind_6 PF13921.6 GAM26175.1 - 0.043 14.1 3.3 0.051 13.8 0.1 2.8 2 1 0 2 2 2 0 Myb-like DNA-binding domain SLIDE PF09111.10 GAM26175.1 - 0.079 13.0 0.1 0.079 13.0 0.1 4.5 5 0 0 5 5 5 0 SLIDE Mucin PF01456.17 GAM26176.1 - 0.12 12.3 29.7 0.23 11.4 29.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_CAR PF05462.11 GAM26177.1 - 2.3e-133 444.0 28.9 2.8e-133 443.8 28.9 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 GAM26177.1 - 2e-06 27.3 23.5 2.6e-06 26.9 22.9 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) FtsX PF02687.21 GAM26177.1 - 7.8 7.0 18.3 0.064 13.7 6.0 2.8 1 1 1 2 2 2 0 FtsX-like permease family PDEase_II PF02112.15 GAM26178.1 - 1.1e-80 271.3 0.1 1.4e-80 271.0 0.1 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 GAM26178.1 - 0.06 12.8 0.1 0.27 10.7 0.0 2.1 2 1 1 3 3 3 0 Beta-lactamase superfamily domain UQ_con PF00179.26 GAM26179.1 - 2.8e-36 124.2 0.0 3.7e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3552 PF12072.8 GAM26180.1 - 1 8.7 2.8 1.4 8.3 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Nop14 PF04147.12 GAM26180.1 - 3.7 5.6 21.9 4.8 5.3 21.9 1.0 1 0 0 1 1 1 0 Nop14-like family Nop25 PF09805.9 GAM26181.1 - 7.8 7.0 14.0 0.94 9.9 6.4 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) EamA PF00892.20 GAM26182.1 - 3.5e-13 49.9 41.0 8.5e-06 26.0 18.9 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 GAM26182.1 - 2.6e-07 30.5 18.0 2.6e-07 30.5 18.0 1.6 2 0 0 2 2 2 1 Solute carrier family 35 EmrE PF13536.6 GAM26182.1 - 0.26 10.9 15.7 0.05 13.2 10.7 2.3 2 1 0 2 2 2 0 Putative multidrug resistance efflux transporter Alpha_kinase PF02816.18 GAM26183.1 - 9.4e-63 211.7 1.1 1.9e-62 210.6 1.1 1.6 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.32 GAM26183.1 - 1e-43 146.4 24.8 7e-06 26.7 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 GAM26183.1 - 1.1e-13 50.8 15.8 0.0025 16.5 0.2 6.9 3 2 4 7 7 7 5 Nucleoporin Nup120/160 WD40_like PF17005.5 GAM26183.1 - 7.1e-09 35.4 2.4 7.4e-06 25.5 0.2 2.5 1 1 0 2 2 2 2 WD40-like domain HPS3_N PF14761.6 GAM26183.1 - 4.7e-06 26.3 0.1 0.99 8.9 0.1 4.8 2 1 3 5 5 5 1 Hermansky-Pudlak syndrome 3 PQQ_3 PF13570.6 GAM26183.1 - 8.1e-06 26.2 0.0 26 5.5 0.0 5.7 6 0 0 6 6 6 0 PQQ-like domain ANAPC4_WD40 PF12894.7 GAM26183.1 - 6e-05 23.3 2.9 2.7 8.4 0.1 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PCSK9_C2 PF18464.1 GAM26183.1 - 0.022 14.8 0.2 8.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain YmzC PF14157.6 GAM26183.1 - 0.044 13.9 0.0 7.1 6.8 0.0 3.7 3 0 0 3 3 3 0 YmzC-like protein DUF1353 PF07087.11 GAM26183.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Ion_trans PF00520.31 GAM26184.1 - 1.9e-33 115.8 65.6 2.7e-22 79.2 35.5 2.4 3 0 0 3 3 3 2 Ion transport protein EF-hand_7 PF13499.6 GAM26184.1 - 2.1e-06 28.1 1.1 0.00024 21.5 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAM26184.1 - 4.8e-05 22.6 2.2 0.016 14.7 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 GAM26184.1 - 0.00034 20.3 8.0 0.047 13.6 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GAM26184.1 - 0.0033 17.2 0.3 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair SUIM_assoc PF16619.5 GAM26184.1 - 4.7 7.3 25.2 6.8 6.8 0.1 4.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PP2C PF00481.21 GAM26185.1 - 5.6e-50 170.4 1.4 6.9e-50 170.1 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C APC_N_CC PF16689.5 GAM26185.1 - 0.00011 22.2 0.7 0.00034 20.6 0.7 1.8 1 0 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain SpoIIE PF07228.12 GAM26185.1 - 0.0075 16.2 0.1 4.8 7.0 0.0 2.8 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Csm1_N PF18504.1 GAM26185.1 - 0.023 15.0 1.7 0.023 15.0 1.7 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain MbeD_MobD PF04899.12 GAM26185.1 - 0.097 12.8 2.9 0.19 11.8 1.0 2.4 2 0 0 2 2 2 0 MbeD/MobD like ABC_tran_CTD PF16326.5 GAM26185.1 - 0.13 12.6 0.1 0.13 12.6 0.1 3.2 2 1 0 3 3 3 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.9 GAM26185.1 - 0.33 11.1 22.6 0.055 13.7 16.8 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4094 PF13334.6 GAM26185.1 - 2.8 8.4 7.8 20 5.7 7.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) JIP_LZII PF16471.5 GAM26185.1 - 7.3 6.8 10.2 1.3 9.2 3.1 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II LIM PF00412.22 GAM26186.1 - 3.4e-25 88.0 29.0 1.1e-12 48.0 12.5 2.1 2 0 0 2 2 2 2 LIM domain Mu-like_Com PF10122.9 GAM26186.1 - 0.24 10.9 8.2 5.8 6.4 0.4 3.4 3 0 0 3 3 3 0 Mu-like prophage protein Com DUF2688 PF10892.8 GAM26186.1 - 0.55 9.8 0.0 0.55 9.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) zf-C3HC4_5 PF17121.5 GAM26186.1 - 1.3 9.0 19.2 2.4 8.1 4.1 3.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) NMD3 PF04981.13 GAM26186.1 - 3.1 7.2 17.9 0.13 11.7 4.7 2.6 2 1 0 2 2 2 0 NMD3 family DNA_ligase_ZBD PF03119.16 GAM26186.1 - 4.6 7.4 8.0 4.3 7.5 0.0 3.2 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain YacG PF03884.14 GAM26186.1 - 9 6.1 14.1 7.8 6.3 0.1 4.2 5 0 0 5 5 5 0 DNA gyrase inhibitor YacG WH1 PF00568.23 GAM26187.1 - 2.9e-22 78.7 0.2 4.4e-22 78.1 0.2 1.2 1 0 0 1 1 1 1 WH1 domain DCP1 PF06058.13 GAM26187.1 - 0.00013 21.9 0.2 0.00022 21.1 0.2 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family PBD PF00786.28 GAM26187.1 - 0.0024 18.2 3.0 0.0027 18.0 0.1 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain DUF2076 PF09849.9 GAM26187.1 - 0.031 14.3 0.8 0.059 13.4 0.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) UPF0370 PF13980.6 GAM26187.1 - 0.73 9.9 3.1 0.85 9.7 1.4 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) WH1 PF00568.23 GAM26188.1 - 3.8e-23 81.5 0.5 5.8e-23 80.9 0.5 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 GAM26188.1 - 6.3e-15 55.3 0.1 1.6e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain DCP1 PF06058.13 GAM26188.1 - 0.00027 20.8 0.2 0.00043 20.2 0.2 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family WH2 PF02205.20 GAM26188.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 WH2 motif GCS PF03074.16 GAM26189.1 - 1e-169 564.7 0.9 1.3e-169 564.4 0.9 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Myb_DNA-binding PF00249.31 GAM26189.1 - 0.043 14.0 0.2 3.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain MNE1 PF13762.6 GAM26189.1 - 0.063 13.3 0.1 0.36 10.8 0.0 2.2 1 1 1 2 2 2 0 Mitochondrial splicing apparatus component TLC PF03219.14 GAM26189.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 TLC ATP/ADP transporter LSM PF01423.22 GAM26190.1 - 4.4e-18 64.7 0.0 5e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain A_deamin PF02137.18 GAM26192.1 - 2.3e-85 286.9 1.5 1e-84 284.8 1.5 1.8 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Mucin PF01456.17 GAM26192.1 - 0.0051 16.8 11.8 0.011 15.7 11.8 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.8 GAM26192.1 - 0.96 9.4 12.5 2.1 8.4 12.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FANCI_S2 PF14676.6 GAM26193.1 - 3.4e-35 121.8 0.3 3.4e-35 121.8 0.3 3.5 3 1 0 3 3 3 1 FANCI solenoid 2 FANCI_HD2 PF14680.6 GAM26193.1 - 3.5e-35 121.4 1.8 3.5e-35 121.4 1.8 3.2 3 0 0 3 3 3 1 FANCI helical domain 2 FANCI_S1 PF14675.6 GAM26193.1 - 2.2e-27 96.1 6.0 3.5e-27 95.4 3.9 2.5 2 0 0 2 2 2 1 FANCI solenoid 1 FANCI_S4 PF14678.6 GAM26193.1 - 6.9e-23 81.1 7.4 6.9e-23 81.1 7.4 3.2 4 0 0 4 4 4 1 FANCI solenoid 4 FANCI_HD1 PF14679.6 GAM26193.1 - 2.3e-10 40.3 0.6 1.1e-09 38.1 0.1 2.6 2 0 0 2 2 2 1 FANCI helical domain 1 BBIP10 PF14777.6 GAM26193.1 - 0.011 15.3 0.2 6 6.5 0.1 2.8 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 Homeodomain PF00046.29 GAM26193.1 - 0.069 13.0 0.4 0.37 10.7 0.1 2.4 2 0 0 2 2 2 0 Homeodomain KxDL PF10241.9 GAM26193.1 - 8.2 6.8 8.0 8.2 6.8 2.0 3.8 3 1 1 4 4 4 0 Uncharacterized conserved protein PA26 PF04636.13 GAM26194.1 - 0.054 12.4 11.5 0.056 12.4 11.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DDHD PF02862.17 GAM26194.1 - 1.4 9.1 10.6 1.7 8.8 10.6 1.3 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 GAM26194.1 - 2.5 7.8 16.2 3.4 7.4 16.2 1.2 1 0 0 1 1 1 0 AAA domain Mem_trans PF03547.18 GAM26194.1 - 3.3 6.0 4.7 3.4 6.0 4.7 1.2 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.14 GAM26194.1 - 3.3 5.9 21.7 4 5.6 21.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Caps_synth_GfcC PF06251.11 GAM26194.1 - 4.7 6.8 10.7 6.1 6.4 3.2 2.1 1 1 1 2 2 2 0 Capsule biosynthesis GfcC Presenilin PF01080.17 GAM26194.1 - 6.1 5.5 17.6 6.7 5.4 17.6 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 GAM26194.1 - 7.2 4.4 14.5 7.4 4.3 14.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S64 PF08192.11 GAM26194.1 - 7.4 4.9 12.9 8.3 4.8 12.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 GAM26194.1 - 9.6 3.2 14.0 10 3.1 14.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 GAM26194.1 - 9.8 5.1 16.5 11 4.9 16.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Calcipressin PF04847.12 GAM26195.1 - 6.4e-08 32.6 0.9 1.2e-07 31.7 0.5 1.6 1 1 1 2 2 2 1 Calcipressin 4_1_CTD PF05902.13 GAM26195.1 - 0.031 14.3 0.3 1.4 9.1 0.1 2.2 2 0 0 2 2 2 0 4.1 protein C-terminal domain (CTD) IQ PF00612.27 GAM26196.1 - 1.4e-07 30.7 8.2 0.0014 18.3 0.6 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif Pep_M12B_propep PF01562.19 GAM26196.1 - 0.069 13.4 0.2 0.29 11.4 0.2 2.1 1 0 0 1 1 1 0 Reprolysin family propeptide PuR_N PF09182.10 GAM26196.1 - 1.6 8.7 4.0 1.1 9.2 1.2 2.1 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Zn_ribbon_SprT PF17283.2 GAM26197.1 - 5.3 7.0 10.3 6.4 6.8 0.0 3.4 3 0 0 3 3 3 0 SprT-like zinc ribbon domain CUB_2 PF02408.20 GAM26198.1 - 0.0069 16.1 0.2 0.014 15.2 0.2 1.6 1 1 0 1 1 1 1 CUB-like domain Gypsy PF07253.11 GAM26198.1 - 0.012 14.2 0.1 0.016 13.8 0.1 1.1 1 0 0 1 1 1 0 Gypsy protein Bactofilin PF04519.13 GAM26198.1 - 0.015 15.6 0.2 0.026 14.8 0.2 1.5 1 0 0 1 1 1 0 Polymer-forming cytoskeletal RasGEF PF00617.19 GAM26201.1 - 1.3e-44 152.5 0.6 6.6e-44 150.2 0.2 2.4 2 0 0 2 2 2 1 RasGEF domain GRAM PF02893.20 GAM26201.1 - 8.2e-15 54.7 0.4 2.1e-14 53.4 0.4 1.7 1 0 0 1 1 1 1 GRAM domain RhoGAP PF00620.27 GAM26201.1 - 2.3e-10 40.5 0.0 6.1e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain Y_phosphatase2 PF03162.13 GAM26203.1 - 4.2e-42 143.5 0.0 4.2e-42 143.5 0.0 1.9 2 1 0 2 2 2 1 Tyrosine phosphatase family Ndc1_Nup PF09531.10 GAM26203.1 - 0.12 11.0 11.7 0.14 10.9 11.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 GAM26203.1 - 0.44 9.3 13.8 0.0075 15.1 7.0 1.5 2 0 0 2 2 2 0 Presenilin Membralin PF09746.9 GAM26203.1 - 0.44 9.5 6.6 0.68 8.9 6.6 1.3 1 0 0 1 1 1 0 Tumour-associated protein Dicty_REP PF05086.12 GAM26203.1 - 5.9 4.7 17.4 0.36 8.8 12.2 1.5 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Tim54 PF11711.8 GAM26203.1 - 8.6 5.0 10.1 5.3 5.7 5.8 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Activator_LAG-3 PF11498.8 GAM26203.1 - 9.5 5.1 38.1 14 4.5 38.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 C1_1 PF00130.22 GAM26204.1 - 5.7e-13 48.5 23.2 5.7e-08 32.5 5.6 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 GAM26204.1 - 0.79 10.1 21.2 4.2 7.8 7.0 2.5 2 0 0 2 2 2 0 C1 domain Vpu PF00558.19 GAM26205.1 - 0.038 13.8 0.4 0.056 13.2 0.4 1.3 1 0 0 1 1 1 0 Vpu protein DUF621 PF04789.15 GAM26206.1 - 0.0057 15.9 0.9 0.01 15.0 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF621) LRR_4 PF12799.7 GAM26206.1 - 1.6 9.3 10.9 5.8 7.5 0.9 4.9 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) Lipase_3 PF01764.25 GAM26207.1 - 2.2e-37 128.0 0.0 3.3e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GAM26207.1 - 2.4e-05 24.0 0.1 0.00022 20.9 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 GAM26207.1 - 0.005 16.6 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 GAM26207.1 - 0.0086 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3089 PF11288.8 GAM26207.1 - 0.02 14.4 0.2 0.092 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Abhydrolase_6 PF12697.7 GAM26207.1 - 0.025 15.2 0.0 0.03 14.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 GAM26207.1 - 0.038 13.7 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_A2E PF12382.8 GAM26208.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon peptidase LRR_6 PF13516.6 GAM26209.1 - 2.3e-21 74.0 14.9 0.0026 17.7 0.1 6.6 6 0 0 6 6 6 5 Leucine Rich repeat Ras PF00071.22 GAM26209.1 - 1.8e-18 66.7 0.0 4.3e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Ras family LRR_4 PF12799.7 GAM26209.1 - 6.5e-07 29.6 5.6 0.028 14.8 0.2 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Roc PF08477.13 GAM26209.1 - 9.6e-07 29.0 0.0 9.6e-07 29.0 0.0 2.1 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase LRR_1 PF00560.33 GAM26209.1 - 0.012 16.0 0.1 22 6.1 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat GAGA_bind PF06217.12 GAM26209.1 - 0.22 11.8 14.7 0.32 11.2 14.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.17 GAM26209.1 - 0.3 11.2 3.9 0.49 10.5 3.9 1.4 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.11 GAM26209.1 - 0.5 8.8 25.8 0.76 8.2 25.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Zip PF02535.22 GAM26209.1 - 5.3 6.2 6.9 7.5 5.7 6.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NUDIX PF00293.28 GAM26210.1 - 1e-16 61.2 0.0 2.7e-16 59.8 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain Ribosomal_S17_N PF16205.5 GAM26211.1 - 1.5e-28 98.9 0.6 2.7e-28 98.1 0.6 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 GAM26211.1 - 3.3e-25 88.0 0.6 4.8e-25 87.4 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 DUF4298 PF14131.6 GAM26212.1 - 0.0095 15.9 2.7 0.012 15.5 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4298) Importin_rep PF18773.1 GAM26212.1 - 0.073 12.8 0.3 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Importin 13 repeat ArfGap PF01412.18 GAM26213.1 - 1.3e-34 118.8 0.6 1.3e-34 118.8 0.6 3.3 4 1 1 5 5 5 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 GAM26214.1 - 0.0001 22.8 13.9 1.1 9.9 0.0 7.8 8 1 1 9 9 9 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM26214.1 - 0.0019 18.5 0.0 1.6 9.1 0.0 4.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DnaB_2 PF07261.11 GAM26214.1 - 0.033 13.9 0.5 0.24 11.2 0.1 2.8 2 0 0 2 2 2 0 Replication initiation and membrane attachment EF-hand_6 PF13405.6 GAM26214.1 - 0.16 12.0 0.2 11 6.3 0.1 3.5 2 0 0 2 2 2 0 EF-hand domain Ank_4 PF13637.6 GAM26214.1 - 1.3 9.7 13.0 15 6.3 0.3 8.0 8 2 2 10 10 10 0 Ankyrin repeats (many copies) Glyco_hydro_31 PF01055.26 GAM26216.1 - 1.5e-153 512.1 7.8 2.2e-153 511.6 7.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAM26216.1 - 3.5e-25 88.5 0.0 6.9e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 GAM26216.1 - 5.2e-10 39.5 0.3 5.2e-10 39.5 0.3 2.9 4 0 0 4 4 4 1 Galactose mutarotase-like DUF5110 PF17137.4 GAM26216.1 - 2.3e-06 27.8 0.1 3.8e-05 23.9 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Chi-conotoxin PF16981.5 GAM26216.1 - 0.079 13.2 0.6 0.17 12.1 0.6 1.6 1 0 0 1 1 1 0 chi-Conotoxin or t superfamily FA_hydroxylase PF04116.13 GAM26217.1 - 2.4e-27 95.9 13.6 2.4e-27 95.9 13.6 2.3 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily DUF1084 PF06454.11 GAM26218.1 - 0.00046 19.6 18.6 0.0012 18.3 18.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Phtf-FEM1B_bdg PF12129.8 GAM26218.1 - 1.1 9.0 8.3 2.2 8.1 3.6 2.6 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor MIG-14_Wnt-bd PF06664.12 GAM26220.1 - 0.065 12.4 7.9 0.085 12.1 7.9 1.0 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF4282 PF14110.6 GAM26220.1 - 8.6 7.2 13.1 5.3e+02 1.4 13.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) Rap_GAP PF02145.15 GAM26221.1 - 1.3e-62 210.7 0.0 1.7e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP LUD_dom PF02589.15 GAM26222.1 - 2.3e-30 105.7 0.0 2.7e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 LUD domain NHL PF01436.21 GAM26222.1 - 0.01 15.8 0.3 0.074 13.1 0.1 2.4 2 0 0 2 2 2 0 NHL repeat HpcH_HpaI PF03328.14 GAM26223.1 - 9.6e-46 155.7 0.7 5.1e-45 153.3 0.6 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 GAM26223.1 - 7e-19 68.2 0.1 1.9e-10 40.5 0.0 2.2 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold BtpA PF03437.15 GAM26223.1 - 0.029 13.8 0.7 0.36 10.2 0.7 2.1 1 1 0 1 1 1 0 BtpA family Globin PF00042.22 GAM26224.1 - 3.5e-08 34.0 0.0 6.6e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Globin Protoglobin PF11563.8 GAM26224.1 - 0.031 14.2 0.0 0.057 13.3 0.0 1.6 1 1 0 1 1 1 0 Protoglobin Halogen_Hydrol PF10112.9 GAM26225.1 - 1.2 9.1 3.7 1.1 9.2 0.1 2.0 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DHHC PF01529.20 GAM26225.1 - 3.6 7.7 9.7 0.91 9.6 3.0 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF1084 PF06454.11 GAM26229.1 - 0.0024 17.3 6.8 0.0035 16.8 6.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) RasGEF PF00617.19 GAM26230.1 - 2.8e-33 115.6 0.2 5.1e-33 114.8 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM26230.1 - 8.8e-16 58.0 1.0 1.8e-15 57.0 0.2 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif TIG PF01833.24 GAM26230.1 - 1.6e-09 37.7 20.2 3.5e-05 23.8 1.1 3.8 4 0 0 4 4 4 2 IPT/TIG domain Adeno_E3_CR2 PF02439.15 GAM26230.1 - 0.0043 16.8 0.6 0.011 15.4 0.6 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Insulin_TMD PF17870.1 GAM26230.1 - 0.0069 16.4 0.2 0.02 15.0 0.2 1.7 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Cas_Csn2 PF09711.10 GAM26230.1 - 0.01 15.5 0.2 0.027 14.2 0.2 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) Collectrin PF16959.5 GAM26230.1 - 0.016 15.0 0.1 0.065 13.0 0.1 2.1 1 0 0 1 1 1 0 Renal amino acid transporter EphA2_TM PF14575.6 GAM26230.1 - 0.019 15.8 0.0 0.046 14.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 GAM26230.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Orthoreo_P10 PF07204.11 GAM26230.1 - 0.089 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Trp_oprn_chp PF09534.10 GAM26230.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SapB_1 PF05184.15 GAM26231.1 - 9.3e-22 76.7 9.0 1.3e-11 44.3 1.6 3.0 3 0 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.17 GAM26231.1 - 5.6e-15 55.2 3.4 8.7e-09 35.3 1.5 3.8 4 0 0 4 4 4 2 Saposin-like type B, region 2 Lung_7-TM_R PF06814.13 GAM26232.1 - 1.4e-15 57.4 12.8 1.4e-15 57.4 12.8 2.2 2 0 0 2 2 2 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 GAM26232.1 - 5.1e-06 26.1 8.7 5.1e-06 26.1 8.7 2.0 2 1 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain RR_TM4-6 PF06459.12 GAM26232.1 - 0.0001 22.2 2.2 0.00018 21.4 1.4 1.7 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 C1ORF64 PF15547.6 GAM26232.1 - 0.11 12.9 0.3 1 9.8 0.1 2.2 2 0 0 2 2 2 0 Steroid receptor-associated and regulated protein DUF4637 PF15470.6 GAM26232.1 - 0.11 12.2 2.1 0.19 11.5 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) GET2 PF08690.10 GAM26232.1 - 0.27 10.9 4.4 0.48 10.1 4.4 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Pox_Ag35 PF03286.14 GAM26232.1 - 2.9 7.6 9.8 4.3 7.1 9.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pkinase PF00069.25 GAM26234.1 - 2.4e-67 227.1 0.6 3.2e-67 226.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26234.1 - 8.7e-47 159.6 0.1 1.3e-46 159.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM26234.1 - 2.3e-06 26.7 1.1 3.7e-06 26.0 0.0 1.8 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 GAM26234.1 - 2.1e-05 24.6 0.0 0.0068 16.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 GAM26234.1 - 0.00048 19.8 0.1 0.0011 18.6 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 GAM26234.1 - 0.0018 17.6 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAM26234.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAM26234.1 - 0.05 12.5 0.2 0.13 11.2 0.2 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 GAM26234.1 - 0.07 12.7 0.1 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Hamartin PF04388.12 GAM26234.1 - 0.092 11.4 5.1 0.15 10.7 5.1 1.3 1 0 0 1 1 1 0 Hamartin protein Sgf11 PF08209.11 GAM26235.1 - 6.9e-08 31.9 0.2 1.2e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Methyltransf_11 PF08241.12 GAM26236.1 - 1.8e-14 54.2 0.0 2.8e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM26236.1 - 1.9e-12 47.7 0.0 3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM26236.1 - 7.5e-10 38.9 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM26236.1 - 4.6e-08 33.0 0.0 6.7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM26236.1 - 4.7e-08 33.7 0.0 7.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAM26236.1 - 0.035 13.4 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 GAM26236.1 - 0.095 12.2 0.0 0.22 11.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain PQ-loop PF04193.14 GAM26238.1 - 2.8e-08 33.4 1.4 6.2e-08 32.3 1.4 1.6 1 0 0 1 1 1 1 PQ loop repeat ER_lumen_recept PF00810.18 GAM26238.1 - 0.056 14.3 0.4 0.12 13.2 0.4 1.5 1 0 0 1 1 1 0 ER lumen protein retaining receptor RasGEF PF00617.19 GAM26239.1 - 1.2e-56 191.7 0.7 4.9e-56 189.7 0.1 2.4 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM26239.1 - 2.2e-20 72.9 0.5 2.2e-20 72.9 0.5 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif FERM_f0 PF16511.5 GAM26239.1 - 1e-15 57.8 3.1 2.8e-08 33.9 0.0 4.4 4 0 0 4 4 4 3 N-terminal or F0 domain of Talin-head FERM FERM_N PF09379.10 GAM26239.1 - 0.00018 21.4 0.3 0.16 11.9 0.0 3.0 2 1 0 2 2 2 2 FERM N-terminal domain Dehydrin PF00257.19 GAM26239.1 - 0.0067 17.0 4.8 0.0067 17.0 4.8 2.4 3 0 0 3 3 3 1 Dehydrin Rad60-SLD PF11976.8 GAM26239.1 - 0.022 14.6 3.2 34 4.4 0.0 5.5 5 0 0 5 5 5 0 Ubiquitin-2 like Rad60 SUMO-like YbjN PF10722.9 GAM26239.1 - 0.023 14.8 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator DUF3439 PF11921.8 GAM26239.1 - 0.52 10.3 10.5 1.3 9.0 10.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Kei1 PF08552.11 GAM26240.1 - 0.48 10.3 9.9 0.54 10.1 9.9 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RIFIN PF02009.16 GAM26240.1 - 1.1 9.1 8.4 1.2 9.0 8.4 1.0 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 GAM26240.1 - 5.7 6.3 10.0 6.7 6.0 10.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RNase_T PF00929.24 GAM26241.1 - 1.1e-10 42.3 0.0 6.6e-10 39.8 0.0 2.0 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 GAM26241.1 - 0.027 14.2 0.0 0.084 12.6 0.0 1.8 1 1 0 1 1 1 0 3'-5' exonuclease Ribosomal_L13e PF01294.18 GAM26241.1 - 0.086 12.7 0.3 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 Ribosomal protein L13e ACOX PF01756.19 GAM26242.1 - 4.4e-43 146.9 0.0 8.1e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 GAM26242.1 - 8.6e-16 58.6 0.0 1.8e-14 54.4 0.0 2.5 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 GAM26242.1 - 4.4e-12 46.0 0.0 8.5e-11 41.9 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAM26242.1 - 0.096 12.9 0.2 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF3439 PF11921.8 GAM26243.1 - 6.3 6.8 13.3 9.4 6.2 13.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_C1 PF00112.23 GAM26244.1 - 2.7e-63 214.0 3.5 3.2e-63 213.7 3.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 GAM26244.1 - 4.9e-10 39.1 0.0 8.7e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 GAM26244.1 - 7.1e-06 25.1 1.4 0.00066 18.6 0.6 2.1 2 0 0 2 2 2 2 Peptidase C1-like family AAA PF00004.29 GAM26245.1 - 8.3e-38 129.8 0.0 1.6e-37 128.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM26245.1 - 5e-10 39.0 0.1 1.2e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAM26245.1 - 8.8e-07 29.0 0.1 3e-06 27.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAM26245.1 - 2.6e-06 27.3 0.1 1.2e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAM26245.1 - 6.3e-06 26.7 1.3 0.00029 21.3 0.0 2.7 1 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 GAM26245.1 - 2.3e-05 24.6 0.0 4.3e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM26245.1 - 5.6e-05 23.4 0.5 0.0016 18.7 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 GAM26245.1 - 0.00011 22.8 0.0 0.00021 21.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 GAM26245.1 - 0.00011 22.3 0.1 0.00034 20.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAM26245.1 - 0.0011 18.9 0.1 0.0044 16.9 0.0 1.9 2 0 0 2 2 2 1 NACHT domain TIP49 PF06068.13 GAM26245.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 GAM26245.1 - 0.0015 18.3 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAM26245.1 - 0.0017 17.7 0.2 0.0035 16.8 0.2 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAM26245.1 - 0.0026 18.1 0.0 0.015 15.7 0.0 2.2 1 1 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.26 GAM26245.1 - 0.0033 17.1 0.1 0.01 15.6 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_2 PF07724.14 GAM26245.1 - 0.0038 17.4 0.0 0.017 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 GAM26245.1 - 0.0061 17.0 0.1 0.035 14.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 GAM26245.1 - 0.0074 16.6 0.1 0.03 14.6 0.0 1.8 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_11 PF13086.6 GAM26245.1 - 0.008 16.0 0.5 0.022 14.5 0.5 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAM26245.1 - 0.0083 15.3 0.1 0.018 14.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 GAM26245.1 - 0.01 15.0 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 GAM26245.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 GAM26245.1 - 0.018 14.7 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM26245.1 - 0.03 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 GAM26245.1 - 0.031 14.2 0.1 11 5.8 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 GAM26245.1 - 0.033 14.4 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 GAM26245.1 - 0.034 14.1 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 GAM26245.1 - 0.035 13.8 0.2 0.21 11.3 0.1 2.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 GAM26245.1 - 0.051 12.8 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 GAM26245.1 - 0.059 13.9 0.2 0.12 12.9 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 GAM26245.1 - 0.097 11.9 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin PF02224.18 GAM26245.1 - 0.1 12.3 0.6 0.32 10.7 0.0 2.1 3 0 0 3 3 3 0 Cytidylate kinase PhoH PF02562.16 GAM26245.1 - 0.11 11.9 0.2 0.25 10.8 0.2 1.6 1 1 0 1 1 1 0 PhoH-like protein CPT PF07931.12 GAM26245.1 - 0.12 12.2 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 GAM26245.1 - 0.13 11.8 1.2 0.45 10.1 0.1 2.3 3 0 0 3 3 3 0 AAA domain AAA_3 PF07726.11 GAM26245.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF572 PF04502.13 GAM26246.1 - 9.4e-64 216.1 0.8 1e-63 216.0 0.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Macoilin PF09726.9 GAM26246.1 - 0.45 9.0 14.5 0.59 8.6 14.5 1.1 1 0 0 1 1 1 0 Macoilin family NAC PF01849.18 GAM26247.1 - 2.9e-17 62.4 0.6 5.6e-17 61.5 0.0 1.8 3 0 0 3 3 3 1 NAC domain Yip1 PF04893.17 GAM26248.1 - 7e-14 51.9 15.0 1.2e-13 51.2 14.6 1.5 1 1 1 2 2 2 1 Yip1 domain YIF1 PF03878.15 GAM26248.1 - 0.044 13.3 7.6 0.059 12.9 6.8 1.7 1 1 0 1 1 1 0 YIF1 SLATT_4 PF18186.1 GAM26248.1 - 0.079 12.6 0.7 0.15 11.7 0.7 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Zap1_zf2 PF18217.1 GAM26251.1 - 0.076 13.0 2.6 0.25 11.4 2.6 1.9 1 0 0 1 1 1 0 Zap1 zinc finger 2 HTH_45 PF14947.6 GAM26251.1 - 0.082 12.9 0.8 0.39 10.7 0.2 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix Ank_2 PF12796.7 GAM26252.1 - 0.02 15.4 0.1 0.57 10.8 0.1 2.1 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Proteasome PF00227.26 GAM26253.1 - 3.8e-60 202.6 0.3 6.6e-60 201.9 0.1 1.5 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM26253.1 - 4.8e-15 54.9 0.1 9.9e-15 53.9 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature WD40 PF00400.32 GAM26254.1 - 2e-38 129.7 16.6 1.1e-07 32.4 0.9 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM26254.1 - 5e-16 58.8 5.8 6.3e-07 29.6 0.7 5.2 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM26254.1 - 2.6e-05 23.7 0.0 0.00098 18.5 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain VID27 PF08553.10 GAM26254.1 - 0.0042 16.2 0.0 2.3 7.2 0.0 2.1 2 0 0 2 2 2 2 VID27 C-terminal WD40-like domain Tox-HDC PF15656.6 GAM26254.1 - 0.056 13.6 0.2 0.92 9.7 0.1 2.4 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature WD40 PF00400.32 GAM26255.1 - 2.3e-23 82.0 16.4 0.018 15.9 0.0 9.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM26255.1 - 1.8e-07 31.4 0.1 0.7 10.2 0.0 6.2 7 0 0 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 GAM26256.1 - 1.7e-65 221.0 0.0 2.1e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26256.1 - 1.2e-19 70.6 0.0 1.8e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM26256.1 - 2.3e-08 34.2 0.0 5.3e-07 29.8 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM26256.1 - 0.015 14.9 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 GAM26256.1 - 0.026 13.9 0.2 0.046 13.1 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM26256.1 - 0.083 11.7 0.2 0.24 10.2 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Dicty_CTDC PF00526.18 GAM26257.1 - 5.4e-50 166.9 200.0 7.7e-11 41.7 11.4 13.1 12 1 1 13 13 13 11 Dictyostelium (slime mold) repeat S1FA PF04689.13 GAM26258.1 - 0.19 11.9 0.1 0.47 10.6 0.1 1.7 1 0 0 1 1 1 0 DNA binding protein S1FA Sigma_reg_N PF13800.6 GAM26258.1 - 5.5 7.3 6.2 11 6.4 0.8 2.9 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Podoplanin PF05808.11 GAM26259.1 - 0.00015 21.9 1.6 0.0003 20.9 1.6 1.6 1 0 0 1 1 1 1 Podoplanin Beta_helix PF13229.6 GAM26259.1 - 0.00017 21.5 42.9 0.0027 17.6 10.9 2.7 1 1 1 2 2 2 2 Right handed beta helix region Adeno_E3_CR2 PF02439.15 GAM26259.1 - 0.00064 19.4 5.2 0.0012 18.6 5.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4690 PF15756.5 GAM26259.1 - 0.07 13.7 0.2 0.15 12.7 0.2 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Protocadherin PF08374.11 GAM26259.1 - 0.073 13.0 2.4 0.082 12.9 1.2 1.7 2 0 0 2 2 2 0 Protocadherin SKG6 PF08693.10 GAM26259.1 - 0.1 12.0 11.6 0.23 10.9 11.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2755 PF10954.8 GAM26259.1 - 0.11 12.5 1.4 0.31 11.0 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2755) DUF2600 PF10776.9 GAM26260.1 - 0.017 14.0 3.7 0.02 13.8 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) Forkhead PF00250.18 GAM26262.1 - 0.0013 18.9 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain DUF3290 PF11694.8 GAM26263.1 - 0.016 15.2 0.4 0.025 14.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) TFIIA PF03153.13 GAM26263.1 - 5.5 6.9 13.5 6.2 6.7 13.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-A20 PF01754.16 GAM26264.1 - 1.4e-11 44.1 7.0 1.4e-11 44.1 7.0 2.1 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 GAM26264.1 - 9.5e-10 38.5 10.1 9.5e-10 38.5 10.1 2.7 2 1 1 3 3 3 1 AN1-like Zinc finger tRNA_m1G_MT PF01746.21 GAM26265.1 - 7.7e-21 74.7 0.1 7.7e-21 74.7 0.1 2.1 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Mucin PF01456.17 GAM26265.1 - 4.2 7.4 60.6 0.12 12.3 24.6 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein CDC24_OB3 PF17244.2 GAM26267.1 - 8.4e-14 51.8 0.6 3.6e-13 49.8 0.1 2.2 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 CDC24_OB2 PF17245.2 GAM26267.1 - 3.9e-06 27.5 1.2 0.00014 22.4 0.0 3.1 3 1 0 3 3 3 1 Cell division control protein 24, OB domain 2 STT3_PglB_C PF18527.1 GAM26267.1 - 0.022 14.9 0.1 0.061 13.4 0.1 1.8 1 0 0 1 1 1 0 STT3/PglB C-terminal beta-barrel domain DUF11 PF01345.18 GAM26267.1 - 0.11 12.8 1.5 0.33 11.3 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF11 FYVE_2 PF02318.16 GAM26268.1 - 3.5 7.9 9.0 0.61 10.3 5.3 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger DUF892 PF05974.12 GAM26269.1 - 0.0051 16.9 1.4 0.0051 16.9 1.4 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF892) PT-VENN PF04829.13 GAM26269.1 - 0.034 14.2 0.1 0.093 12.8 0.1 1.7 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Sporozoite_P67 PF05642.11 GAM26269.1 - 0.095 10.8 2.5 0.11 10.5 2.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Menin PF05053.13 GAM26269.1 - 0.13 10.6 5.0 0.17 10.3 5.0 1.1 1 0 0 1 1 1 0 Menin UPF0184 PF03670.13 GAM26269.1 - 0.63 10.5 15.2 0.68 10.4 0.1 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) LRR19-TM PF15176.6 GAM26269.1 - 0.63 10.1 4.6 3.1 7.9 3.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF4834 PF16118.5 GAM26269.1 - 0.83 10.6 17.9 0.55 11.2 8.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Paramyxo_ncap PF00973.19 GAM26269.1 - 1.8 7.4 8.1 2.6 6.9 8.1 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SIN1 PF05422.12 GAM26269.1 - 2.8 8.5 17.9 0.15 12.6 12.1 1.7 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) Spt20 PF12090.8 GAM26269.1 - 2.8 7.5 23.1 0.086 12.4 13.9 2.1 2 0 0 2 2 2 0 Spt20 family Serinc PF03348.15 GAM26269.1 - 3.5 6.5 4.2 10 4.9 3.9 1.7 2 0 0 2 2 2 0 Serine incorporator (Serinc) GEMIN8 PF15348.6 GAM26269.1 - 6.2 7.1 19.9 1.1 9.5 15.7 1.8 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DENN PF02141.21 GAM26270.1 - 3.2e-35 121.8 6.7 4.7e-35 121.2 6.7 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAM26270.1 - 7.9e-08 32.9 0.2 2e-07 31.7 0.2 1.7 1 0 0 1 1 1 1 uDENN domain SPA PF08616.10 GAM26270.1 - 3.6e-05 23.7 0.6 8.6e-05 22.5 0.6 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 GAM26270.1 - 0.00072 18.3 0.8 0.00099 17.9 0.8 1.2 1 0 0 1 1 1 1 Transport protein Avl9 LIM PF00412.22 GAM26272.1 - 4.7e-10 39.5 23.7 7.5e-07 29.3 7.0 2.8 2 1 1 3 3 3 2 LIM domain Zn_ribbon_2 PF12674.7 GAM26272.1 - 0.032 14.9 2.3 0.8 10.4 0.4 3.1 2 0 0 2 2 2 0 Putative zinc ribbon domain Lar_restr_allev PF14354.6 GAM26272.1 - 4.4 7.8 17.6 15 6.1 4.7 3.7 2 2 0 2 2 2 0 Restriction alleviation protein Lar Serinc PF03348.15 GAM26273.1 - 2e-60 204.9 20.8 2.6e-60 204.6 20.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) LRR_6 PF13516.6 GAM26274.1 - 2.2e-21 74.0 42.0 0.00046 20.0 0.3 12.0 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.7 GAM26274.1 - 2.5e-11 43.6 33.0 0.00077 19.8 1.1 7.9 5 1 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM26274.1 - 1.1e-08 34.5 28.9 1.6 9.6 0.1 10.1 11 0 0 11 11 11 5 Leucine Rich Repeat LRR_8 PF13855.6 GAM26274.1 - 0.0006 19.5 36.0 0.13 12.1 4.9 8.0 3 3 5 8 8 8 4 Leucine rich repeat DEAD PF00270.29 GAM26275.1 - 1.8e-16 60.4 0.0 4.3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM26275.1 - 1.1e-13 51.6 0.0 1.1e-13 51.6 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAM26275.1 - 9.6e-08 32.4 0.2 8.3e-07 29.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RRM_5 PF13893.6 GAM26276.1 - 1.5e-45 153.9 3.4 1.2e-28 99.2 0.1 3.4 2 1 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GAM26276.1 - 7e-20 70.6 0.4 1.5e-06 27.9 0.0 5.3 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM26276.1 - 1.6e-06 27.9 0.2 0.00041 20.2 0.0 3.6 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_8 PF11835.8 GAM26276.1 - 6.3e-05 23.1 0.0 0.00042 20.5 0.0 2.2 2 0 0 2 2 2 1 RRM-like domain Limkain-b1 PF11608.8 GAM26276.1 - 0.024 14.7 0.0 2.5 8.2 0.0 3.4 4 0 0 4 4 4 0 Limkain b1 RL PF17797.1 GAM26276.1 - 0.055 13.4 0.7 0.63 10.0 0.2 2.8 2 1 0 2 2 2 0 RL domain Chorein_N PF12624.7 GAM26277.1 - 1e-20 74.0 2.9 4.7e-20 71.8 1.3 2.8 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 HDV_ag PF01517.18 GAM26277.1 - 0.0037 17.1 1.6 0.0037 17.1 1.6 1.8 2 0 0 2 2 2 1 Hepatitis delta virus delta antigen DUF4349 PF14257.6 GAM26277.1 - 0.2 11.1 5.0 2.6 7.5 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF4407 PF14362.6 GAM26277.1 - 0.23 10.8 3.2 0.59 9.4 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 GAM26277.1 - 0.82 9.1 14.6 0.057 12.9 8.9 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 ADH_zinc_N PF00107.26 GAM26278.1 - 2.2e-24 85.9 0.0 6.2e-24 84.4 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM26278.1 - 1.3e-10 41.1 0.0 2.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM26278.1 - 3.5e-08 34.6 0.0 8.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.25 GAM26278.1 - 0.0011 18.5 0.3 0.0016 17.9 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.21 GAM26278.1 - 0.002 17.5 0.5 0.0034 16.7 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CHB_HEX_C_1 PF13290.6 GAM26279.1 - 5.3e-14 52.0 8.1 5.3e-14 52.0 8.1 2.6 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 GAM26279.1 - 4.3e-12 46.0 3.4 1.2e-11 44.6 3.4 1.8 1 0 0 1 1 1 1 Fn3 associated Capsid_NCLDV PF04451.12 GAM26279.1 - 0.011 15.5 0.4 0.028 14.2 0.1 1.8 2 0 0 2 2 2 0 Large eukaryotic DNA virus major capsid protein FliD_N PF02465.18 GAM26279.1 - 0.033 14.9 1.4 0.033 14.9 1.4 3.4 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ependymin PF00811.18 GAM26281.1 - 0.055 13.7 0.1 0.12 12.7 0.0 1.5 2 0 0 2 2 2 0 Ependymin Mito_carr PF00153.27 GAM26282.1 - 4.7e-56 186.7 5.9 6.6e-20 70.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1539 PF07560.11 GAM26282.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Ribonuc_red_sm PF00268.21 GAM26282.1 - 0.17 11.3 0.5 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 Ribonucleotide reductase, small chain OTU PF02338.19 GAM26283.1 - 4.4e-11 43.4 1.3 1.6e-10 41.6 0.0 2.5 2 0 0 2 2 2 1 OTU-like cysteine protease SLATT_3 PF18184.1 GAM26284.1 - 2.8 8.1 0.0 2.8 8.1 0.0 2.8 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 3 DUF4690 PF15756.5 GAM26285.1 - 0.00026 21.5 1.5 0.00046 20.7 0.9 1.7 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Syndecan PF01034.20 GAM26285.1 - 2.1 8.3 5.3 4.2 7.4 5.3 1.5 1 0 0 1 1 1 0 Syndecan domain DUF5123 PF17161.4 GAM26285.1 - 3.8 8.6 12.5 8.5 7.5 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) Insulin_TMD PF17870.1 GAM26285.1 - 4.2 7.5 5.9 7.9 6.6 5.9 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment CarboxypepD_reg PF13620.6 GAM26286.1 - 7.1e-47 157.6 17.0 5.8e-08 32.9 0.8 9.6 10 0 0 10 10 10 7 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 GAM26286.1 - 1.3e-22 80.1 17.3 0.0019 18.4 0.0 9.3 9 0 0 9 9 9 6 SdrD B-like domain CarbopepD_reg_2 PF13715.6 GAM26286.1 - 1.7e-16 60.0 18.5 1.8e-05 24.6 0.4 8.1 8 0 0 8 8 8 5 CarboxypepD_reg-like domain DUF2012 PF09430.10 GAM26286.1 - 8.7e-14 51.7 1.0 0.25 11.5 0.0 8.0 9 0 0 9 9 9 3 Protein of unknown function (DUF2012) SpaA PF17802.1 GAM26286.1 - 6.6e-13 48.8 7.9 0.038 14.3 0.0 8.0 8 1 0 8 8 8 3 Prealbumin-like fold domain bMG3 PF11974.8 GAM26286.1 - 2.7e-07 30.6 4.2 0.072 13.1 0.1 5.1 6 1 0 6 6 5 2 Bacterial alpha-2-macroglobulin MG3 domain phage_tail_N PF08400.10 GAM26286.1 - 2.2e-06 27.7 4.0 0.64 10.0 0.0 5.7 6 0 0 6 6 6 2 Prophage tail fibre N-terminal fn3_3 PF14686.6 GAM26286.1 - 1.3e-05 24.9 0.5 3.7 7.4 0.1 5.7 5 0 0 5 5 5 1 Polysaccharide lyase family 4, domain II DUF2846 PF11008.8 GAM26286.1 - 0.00023 21.1 0.4 1.3 9.1 0.0 5.4 5 0 0 5 5 5 1 Protein of unknown function (DUF2846) MetallophosN PF16371.5 GAM26286.1 - 0.00069 19.8 6.3 0.025 14.8 0.4 5.0 6 0 0 6 6 5 1 N terminal of Calcineurin-like phosphoesterase fn3 PF00041.21 GAM26286.1 - 0.00088 19.6 0.1 1.2 9.5 0.1 4.0 3 0 0 3 3 3 1 Fibronectin type III domain Dioxygenase_C PF00775.21 GAM26286.1 - 0.0036 16.8 0.1 12 5.3 0.0 4.3 4 0 0 4 4 4 0 Dioxygenase Big_1 PF02369.16 GAM26286.1 - 0.028 14.4 11.8 47 4.1 0.0 6.4 7 0 0 7 7 7 0 Bacterial Ig-like domain (group 1) Big_7 PF17957.1 GAM26286.1 - 0.092 13.5 0.2 0.092 13.5 0.2 4.2 5 0 0 5 5 4 0 Bacterial Ig domain Big_3_5 PF16640.5 GAM26286.1 - 2.7 8.2 6.0 6.7 7.0 0.0 4.3 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Secretin_N_2 PF07655.13 GAM26287.1 - 0.017 15.7 1.2 0.017 15.7 1.2 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4834 PF16118.5 GAM26287.1 - 0.36 11.8 0.2 0.36 11.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Beta_helix PF13229.6 GAM26288.1 - 1.9e-05 24.6 15.8 1.9e-05 24.6 15.8 2.4 1 1 1 2 2 2 1 Right handed beta helix region DUF4690 PF15756.5 GAM26291.1 - 0.00042 20.8 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage PTP_tm PF18861.1 GAM26291.1 - 0.37 10.7 3.9 0.22 11.5 1.4 1.9 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4690 PF15756.5 GAM26292.1 - 0.0021 18.6 2.6 0.0066 17.0 2.6 1.9 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Response_reg PF00072.24 GAM26294.1 - 2.8e-20 72.5 0.1 8e-20 71.1 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain LRR_8 PF13855.6 GAM26294.1 - 2.6e-09 36.7 25.1 0.0018 18.0 0.7 5.3 3 2 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 GAM26294.1 - 4.9e-09 36.3 38.9 0.012 16.1 1.0 7.7 5 2 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAM26294.1 - 1.4e-06 27.8 31.8 0.35 11.0 0.1 10.1 10 0 0 10 10 10 3 Leucine Rich repeat SUIM_assoc PF16619.5 GAM26294.1 - 0.016 15.2 1.1 0.016 15.2 1.1 2.9 2 1 0 2 2 1 0 Unstructured region C-term to UIM in Ataxin3 SR-25 PF10500.9 GAM26294.1 - 0.23 11.0 13.0 0.24 11.0 1.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 GAM26294.1 - 0.73 10.5 11.8 3.8 8.2 1.9 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein TERB2 PF15101.6 GAM26294.1 - 2 8.4 8.7 4.1 7.4 1.8 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 LRR_1 PF00560.33 GAM26294.1 - 2.5 9.0 28.2 36 5.5 0.0 9.2 8 2 0 8 8 8 0 Leucine Rich Repeat DUF717 PF05338.12 GAM26294.1 - 2.7 8.2 7.0 89 3.3 0.2 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF717) TraG-D_C PF12696.7 GAM26294.1 - 7.5 6.6 10.5 0.22 11.5 1.4 2.3 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG UCH PF00443.29 GAM26295.1 - 8.5e-47 159.8 0.0 1.1e-46 159.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 GAM26295.1 - 6.3e-22 77.1 0.1 1.6e-21 75.8 0.1 1.8 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 GAM26295.1 - 1.3e-19 69.7 0.3 1.2e-09 37.8 0.2 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 GAM26295.1 - 8.3e-17 61.3 0.0 7.1e-15 55.1 0.0 2.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GAM26295.1 - 2.6e-13 50.3 0.1 2.7e-12 47.0 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ank_2 PF12796.7 GAM26296.1 - 1.4e-07 32.0 13.5 0.16 12.6 0.0 8.0 6 5 2 8 8 8 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26296.1 - 0.022 15.3 19.3 20 5.9 0.0 9.4 9 2 1 10 10 10 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26296.1 - 0.084 13.5 21.3 21 6.1 0.0 11.0 13 0 0 13 13 13 0 Ankyrin repeat SIP1 PF04938.12 GAM26296.1 - 0.43 10.3 2.6 1.2 8.8 0.7 2.4 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) TFIIA PF03153.13 GAM26297.1 - 0.0007 19.7 27.7 0.053 13.5 8.9 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 GAM26297.1 - 4 7.3 14.2 5 7.0 4.2 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Cyclin PF08613.11 GAM26299.1 - 0.022 15.2 0.1 5.6 7.3 0.1 2.1 2 0 0 2 2 2 0 Cyclin DUF4972 PF16342.5 GAM26299.1 - 0.061 13.0 0.4 0.22 11.2 0.0 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4972) TAF PF02969.17 GAM26299.1 - 0.076 13.2 0.6 0.2 11.8 0.4 1.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) MTS PF05175.14 GAM26300.1 - 1.4e-08 34.5 0.0 1.6e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 GAM26300.1 - 0.0012 18.3 0.0 0.65 9.3 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 GAM26300.1 - 0.0044 18.0 0.0 0.011 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAM26300.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_12 PF08242.12 GAM26300.1 - 0.021 15.6 0.0 0.13 13.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 GAM26300.1 - 0.16 11.4 0.1 9.2 5.6 0.0 2.1 1 1 0 2 2 2 0 RRNA methyltransferase AviRa p450 PF00067.22 GAM26301.1 - 1.3e-102 344.0 0.0 1.5e-102 343.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Beta_helix PF13229.6 GAM26302.1 - 0.0012 18.8 44.6 0.0079 16.0 17.8 2.6 1 1 1 2 2 2 2 Right handed beta helix region VSP PF03302.13 GAM26302.1 - 0.89 8.3 7.5 0.3 9.9 4.7 1.5 1 1 0 1 1 1 0 Giardia variant-specific surface protein CSN8_PSD8_EIF3K PF10075.9 GAM26303.1 - 9.8e-23 80.7 1.6 9.8e-23 80.7 1.6 2.0 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 GAM26303.1 - 0.00013 22.4 0.6 0.00037 21.0 0.6 1.7 1 0 0 1 1 1 1 PCI domain Ank_2 PF12796.7 GAM26304.1 - 3.6e-21 75.5 1.2 1.5e-13 51.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26304.1 - 8.2e-20 70.9 0.3 1.1e-06 29.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM26304.1 - 5.9e-19 67.9 0.7 8e-10 38.8 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM26304.1 - 5.4e-11 42.4 0.2 0.00013 22.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 GAM26304.1 - 3.9e-10 39.1 0.4 0.00049 20.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Glyco_hydro_31 PF01055.26 GAM26305.1 - 4.6e-151 504.0 3.8 5.6e-151 503.7 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAM26305.1 - 2.7e-24 85.6 0.0 5.5e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 GAM26305.1 - 1.5e-13 50.9 0.3 1.2e-12 48.0 0.4 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 GAM26305.1 - 6.4e-07 29.6 0.1 2e-06 28.0 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) MFS_1 PF07690.16 GAM26306.1 - 2.1e-68 230.8 23.0 8.1e-45 153.3 6.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM26306.1 - 2.7e-17 62.7 20.2 7e-09 35.0 3.1 3.4 1 1 2 3 3 3 2 MFS_1 like family Sugar_tr PF00083.24 GAM26306.1 - 9e-15 54.5 21.3 1.3e-13 50.7 2.6 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 GAM26306.1 - 1.6e-14 53.3 23.2 3.4e-07 29.2 5.0 3.3 1 1 2 3 3 3 2 MFS/sugar transport protein MFS_4 PF06779.14 GAM26306.1 - 1.8e-10 40.7 10.1 3.6e-08 33.1 1.2 2.4 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 GAM26306.1 - 8e-07 27.8 14.5 4.3e-05 22.1 13.9 2.8 1 1 1 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.19 GAM26306.1 - 9.9e-07 27.9 22.4 3.1e-05 23.0 1.8 3.4 3 1 0 3 3 3 2 LacY proton/sugar symporter BT1 PF03092.16 GAM26306.1 - 1.7e-05 23.3 11.3 0.059 11.6 0.0 3.6 1 1 0 3 3 3 3 BT1 family OATP PF03137.20 GAM26306.1 - 0.00011 20.7 21.1 0.00041 18.8 5.6 4.3 1 1 2 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family PTR2 PF00854.21 GAM26306.1 - 0.0023 16.8 13.2 0.013 14.4 1.4 3.2 3 0 0 3 3 3 1 POT family Pam17 PF08566.10 GAM26306.1 - 1 9.2 6.3 6.1 6.7 0.3 3.2 2 2 2 4 4 4 0 Mitochondrial import protein Pam17 FNIP PF05725.12 GAM26307.1 - 2.2e-09 37.3 4.0 0.042 14.0 0.0 5.2 3 2 2 5 5 5 5 FNIP Repeat zf-RING_2 PF13639.6 GAM26307.1 - 0.084 13.2 3.3 0.18 12.2 3.3 1.6 1 0 0 1 1 1 0 Ring finger domain DUF4367 PF14285.6 GAM26309.1 - 0.056 13.9 1.4 0.15 12.5 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Dus PF01207.17 GAM26310.1 - 1.5e-72 244.4 0.0 2e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 GAM26310.1 - 0.00071 19.0 0.1 0.002 17.5 0.1 1.7 1 1 0 1 1 1 1 Thiamine monophosphate synthase DUF561 PF04481.12 GAM26310.1 - 0.00095 18.4 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF561) DHO_dh PF01180.21 GAM26310.1 - 0.034 13.4 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 GAM26310.1 - 0.051 13.0 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Synaptobrevin PF00957.21 GAM26311.1 - 6.3e-12 45.1 1.7 5.2e-11 42.2 1.1 2.1 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 GAM26311.1 - 0.00045 20.2 0.0 0.00069 19.6 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Gp-FAR-1 PF05823.12 GAM26311.1 - 0.0023 18.3 0.5 0.0046 17.3 0.4 1.5 2 0 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF3437 PF11919.8 GAM26311.1 - 0.12 12.3 0.8 0.43 10.5 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) 7tm_3 PF00003.22 GAM26312.1 - 2.1e-44 152.1 27.1 3.2e-44 151.4 27.1 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 GAM26312.1 - 1.9e-38 132.5 0.1 3.1e-38 131.8 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 GAM26312.1 - 3.9e-09 36.6 2.0 6.7e-09 35.9 2.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Phage_holin_3_6 PF07332.11 GAM26312.1 - 1.6 8.8 0.0 1.6 8.8 0.0 3.4 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SNARE_assoc PF09335.11 GAM26313.1 - 2.2e-22 79.8 5.9 2.2e-22 79.8 5.9 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2722 PF10846.8 GAM26314.1 - 3.8e-05 22.8 5.0 3.8e-05 22.8 5.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) Ndc1_Nup PF09531.10 GAM26314.1 - 4.7 5.8 11.1 0.25 10.0 1.9 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup EF-hand_6 PF13405.6 GAM26315.1 - 5.6e-42 138.1 16.1 0.0013 18.5 0.2 10.4 10 0 0 10 10 10 10 EF-hand domain EF-hand_1 PF00036.32 GAM26315.1 - 2.1e-39 130.2 21.3 0.0024 17.3 0.0 10.3 10 0 0 10 10 10 10 EF hand EF-hand_7 PF13499.6 GAM26315.1 - 7.8e-39 132.0 11.7 7.7e-07 29.5 0.1 6.0 5 1 1 6 6 6 6 EF-hand domain pair EF-hand_5 PF13202.6 GAM26315.1 - 1.7e-31 106.3 27.0 0.0012 18.3 0.1 10.2 10 0 0 10 10 10 9 EF hand EF-hand_8 PF13833.6 GAM26315.1 - 5.1e-22 77.5 17.2 0.0022 17.8 0.4 10.2 9 1 1 10 10 10 7 EF-hand domain pair EF-hand_9 PF14658.6 GAM26315.1 - 1.5e-10 41.3 1.3 6.3 7.2 0.0 8.1 7 2 1 8 8 8 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAM26315.1 - 7.7e-10 39.1 5.4 16 5.9 0.0 7.8 5 3 3 8 8 8 0 Secreted protein acidic and rich in cysteine Ca binding region Excalibur PF05901.11 GAM26315.1 - 5.5e-05 23.7 2.7 50 4.6 0.0 6.0 6 0 0 6 6 6 0 Excalibur calcium-binding domain EF-hand_10 PF14788.6 GAM26315.1 - 0.00049 19.9 0.0 80 3.2 0.0 6.2 8 0 0 8 8 7 0 EF hand Dockerin_1 PF00404.18 GAM26315.1 - 0.00087 19.4 47.1 2.1 8.6 0.1 9.0 5 4 4 9 9 9 3 Dockerin type I domain VWA_2 PF13519.6 GAM26315.1 - 0.0013 19.3 4.3 34 5.1 0.0 5.2 5 1 1 6 6 5 0 von Willebrand factor type A domain DOMON PF03351.17 GAM26315.1 - 0.0053 17.0 2.3 4.9 7.4 0.2 3.8 3 0 0 3 3 3 1 DOMON domain Neocarzinostat PF00960.18 GAM26315.1 - 0.035 14.1 0.4 5.9 6.9 0.0 3.5 4 0 0 4 4 4 0 Neocarzinostatin family GSH-S_N PF02951.14 GAM26315.1 - 0.054 13.6 11.0 3.8 7.6 0.2 4.8 5 0 0 5 5 5 0 Prokaryotic glutathione synthetase, N-terminal domain GyrI-like PF06445.15 GAM26315.1 - 0.066 13.5 0.0 18 5.6 0.0 2.5 2 0 0 2 2 2 0 GyrI-like small molecule binding domain DNA_methylase PF00145.17 GAM26315.1 - 0.08 12.3 9.9 1.5 8.1 1.6 3.2 1 1 2 3 3 3 0 C-5 cytosine-specific DNA methylase Pex14_N PF04695.13 GAM26315.1 - 0.81 10.3 36.9 0.039 14.6 10.9 4.2 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UPF0552 PF10574.9 GAM26317.1 - 5.7e-21 74.9 0.0 1.2e-20 73.8 0.0 1.5 1 1 0 1 1 1 1 Arp2/3-interacting proteins Arpin RPN5_C PF18098.1 GAM26317.1 - 1.3 9.1 3.5 2.3 8.4 0.8 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain Cyclin PF08613.11 GAM26318.1 - 3.4e-33 115.3 0.3 3.4e-33 115.3 0.3 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAM26318.1 - 4.1e-12 45.9 0.1 7.7e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain AF-4 PF05110.13 GAM26318.1 - 0.00086 17.6 9.5 0.0011 17.2 9.5 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein MMU163 PF17119.5 GAM26318.1 - 1.5 7.9 5.1 1 8.5 3.0 1.7 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Macoilin PF09726.9 GAM26318.1 - 3.2 6.2 8.7 4.2 5.8 8.7 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 GAM26318.1 - 4.9 6.7 12.1 7 6.2 12.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase_Tyr PF07714.17 GAM26319.1 - 1.7e-51 175.0 0.1 2.8e-51 174.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM26319.1 - 6.3e-51 173.3 0.0 6.3e-51 173.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain RGS PF00615.19 GAM26319.1 - 1.3e-18 67.4 0.2 3.2e-18 66.1 0.2 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain APH PF01636.23 GAM26319.1 - 0.033 14.1 0.0 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family PIP49_N PF14875.6 GAM26319.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.9 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 FTA2 PF13095.6 GAM26319.1 - 0.27 10.8 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Adenosine_kin PF04008.14 GAM26320.1 - 0.058 13.2 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Adenosine specific kinase NAGLU_N PF12971.7 GAM26320.1 - 0.1 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Toxin-JAB1 PF15659.6 GAM26320.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 JAB-like toxin 1 ATG16 PF08614.11 GAM26321.1 - 0.00011 22.5 29.8 0.00011 22.5 29.8 4.4 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) IFT20 PF14931.6 GAM26321.1 - 0.0008 19.6 6.8 0.0008 19.6 6.8 4.7 3 2 0 4 4 4 1 Intraflagellar transport complex B, subunit 20 TUG-UBL1 PF11470.8 GAM26321.1 - 0.00092 19.4 1.1 0.2 11.9 0.0 3.3 3 0 0 3 3 3 1 TUG ubiquitin-like domain CALCOCO1 PF07888.11 GAM26321.1 - 0.0023 16.9 13.3 0.0023 16.9 13.3 3.7 1 1 2 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 GAM26321.1 - 0.0058 16.7 22.0 0.0058 16.7 22.0 5.5 1 1 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ubiquitin PF00240.23 GAM26321.1 - 0.006 16.3 0.6 0.17 11.7 0.0 3.3 3 0 0 3 3 3 1 Ubiquitin family DUF1192 PF06698.11 GAM26321.1 - 0.13 12.3 0.2 0.13 12.3 0.2 6.5 4 2 2 6 6 6 0 Protein of unknown function (DUF1192) DUF3467 PF11950.8 GAM26321.1 - 0.17 12.1 3.2 0.74 10.0 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3467) Spc7 PF08317.11 GAM26321.1 - 2.7 6.8 69.4 0.011 14.6 15.5 3.5 1 1 3 4 4 4 0 Spc7 kinetochore protein Filament PF00038.21 GAM26321.1 - 7.3 6.1 67.5 0.046 13.3 20.7 2.7 1 1 1 2 2 2 0 Intermediate filament protein Stm1_N PF09598.10 GAM26322.1 - 0.097 13.5 1.3 4.4 8.2 0.1 2.5 2 0 0 2 2 2 0 Stm1 Fer2 PF00111.27 GAM26323.1 - 4.1e-15 55.5 0.1 5.5e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 GAM26323.1 - 0.085 12.9 0.4 0.43 10.6 0.2 2.2 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DnaJ-X PF14308.6 GAM26324.1 - 5e-25 88.2 4.0 1.1e-24 87.1 4.0 1.5 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAM26325.1 - 7.2e-28 96.5 2.5 9.8e-28 96.1 2.5 1.2 1 0 0 1 1 1 1 DnaJ domain HSP70 PF00012.20 GAM26326.1 - 6e-251 833.8 12.6 7.3e-251 833.6 12.6 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM26326.1 - 1.2e-14 53.9 3.1 9.3e-12 44.4 0.1 2.8 3 1 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GAM26326.1 - 7.9e-05 22.5 0.1 0.0067 16.2 0.0 2.8 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GAM26326.1 - 0.0047 17.3 12.0 4.2 7.8 0.0 4.4 3 2 0 3 3 3 2 Cell division protein FtsA QRPTase_C PF01729.19 GAM26326.1 - 2 8.1 7.5 1.2 8.9 0.1 3.3 3 1 0 4 4 4 0 Quinolinate phosphoribosyl transferase, C-terminal domain CYYR1 PF10873.8 GAM26327.1 - 0.0065 16.9 0.4 0.024 15.1 0.4 2.0 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Podoplanin PF05808.11 GAM26327.1 - 0.0071 16.5 0.1 0.0071 16.5 0.1 1.7 2 0 0 2 2 2 1 Podoplanin EphA2_TM PF14575.6 GAM26327.1 - 0.44 11.5 1.8 1.8 9.5 0.6 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain EF-hand_1 PF00036.32 GAM26328.1 - 5.4e-31 103.8 9.9 7.6e-05 22.0 0.0 7.7 7 0 0 7 7 7 7 EF hand EF-hand_6 PF13405.6 GAM26328.1 - 2.1e-26 89.6 9.8 0.0095 15.8 0.0 7.5 7 0 0 7 7 7 7 EF-hand domain EF-hand_7 PF13499.6 GAM26328.1 - 5.3e-24 84.5 1.1 5.3e-07 30.0 0.1 5.0 4 2 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 GAM26328.1 - 6.7e-20 69.6 16.8 0.00027 20.3 0.0 7.9 8 0 0 8 8 8 7 EF hand EF-hand_8 PF13833.6 GAM26328.1 - 1.8e-14 53.3 6.6 0.085 12.7 0.0 6.5 7 0 0 7 7 7 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM26328.1 - 0.00012 22.4 0.0 7.6 6.9 0.0 4.4 4 1 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region FG-GAP PF01839.23 GAM26328.1 - 0.031 14.4 0.5 11 6.2 0.0 3.7 3 0 0 3 3 3 0 FG-GAP repeat EF-hand_9 PF14658.6 GAM26328.1 - 0.082 13.2 0.0 41 4.6 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain CutC PF03932.14 GAM26328.1 - 0.12 11.8 0.1 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 CutC family Excalibur PF05901.11 GAM26328.1 - 0.12 13.0 1.7 41 4.9 0.0 4.2 5 0 0 5 5 5 0 Excalibur calcium-binding domain Tli4_N PF18443.1 GAM26329.1 - 0.031 14.7 0.1 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain IL28A PF15177.6 GAM26329.1 - 0.092 12.6 1.9 0.23 11.3 0.0 2.2 2 1 0 2 2 2 0 Interleukin-28A tRNA-synt_2b PF00587.25 GAM26330.1 - 6.2e-37 127.3 0.0 1.4e-36 126.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAM26330.1 - 3.3e-20 72.0 0.4 7.1e-20 71.0 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 GAM26330.1 - 1.7e-09 37.6 0.0 3.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain TFIID_20kDa PF03847.13 GAM26331.1 - 2.8e-29 101.4 0.6 4.8e-29 100.7 0.6 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIIA PF03153.13 GAM26331.1 - 0.0012 18.9 15.7 0.0012 18.9 15.7 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SSP160 PF06933.11 GAM26331.1 - 0.0018 16.6 8.0 0.0018 16.6 8.0 3.3 2 1 1 3 3 3 1 Special lobe-specific silk protein SSP160 CDC27 PF09507.10 GAM26331.1 - 0.0049 16.3 25.7 0.0049 16.3 25.7 2.2 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 SR-25 PF10500.9 GAM26331.1 - 0.11 12.1 51.3 0.015 14.9 32.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 GAM26331.1 - 0.11 12.2 27.5 0.21 11.3 21.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 GAM26331.1 - 0.39 10.3 30.1 0.064 12.8 20.0 2.3 2 0 0 2 2 2 0 PPP4R2 Spore_coat_CotO PF14153.6 GAM26331.1 - 4.5 7.2 28.7 4.3 7.2 3.5 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Sec15 PF04091.12 GAM26333.1 - 1.7e-55 188.6 8.1 1.7e-55 188.6 8.1 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 GAM26333.1 - 4.7e-05 23.6 0.3 0.00023 21.4 0.0 2.4 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Sec5 PF15469.6 GAM26333.1 - 0.0034 17.2 4.0 0.0034 17.2 4.0 2.4 2 1 0 2 2 2 1 Exocyst complex component Sec5 Sec8_exocyst PF04048.14 GAM26333.1 - 0.27 11.1 6.5 1 9.3 0.7 3.8 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain zf-RING_9 PF13901.6 GAM26333.1 - 1.3 9.0 7.8 1.6 8.6 2.0 3.1 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon TFIIF_alpha PF05793.12 GAM26333.1 - 1.7 7.2 31.2 0.029 13.0 24.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cation_ATPase_C PF00689.21 GAM26334.1 - 1.4e-45 155.2 5.2 1.4e-45 155.2 5.2 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAM26334.1 - 4.2e-34 117.6 1.8 4.2e-34 117.6 1.8 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAM26334.1 - 1.1e-24 86.3 0.0 1.9e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM26334.1 - 2.6e-20 73.6 0.0 7.4e-20 72.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM26334.1 - 4.6e-11 42.3 0.8 3.7e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM26334.1 - 0.00016 21.5 0.1 0.013 15.2 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3792 PF12670.7 GAM26334.1 - 0.003 17.7 0.4 0.003 17.7 0.4 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF3792) DUF3290 PF11694.8 GAM26334.1 - 0.12 12.4 0.4 0.32 11.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Wzy_C PF04932.15 GAM26334.1 - 0.28 10.8 4.8 0.25 10.9 0.1 2.9 3 0 0 3 3 3 0 O-Antigen ligase Hydrolase_4 PF12146.8 GAM26335.1 - 1.3e-18 67.1 0.0 7.9e-14 51.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM26335.1 - 4.9e-08 32.9 0.0 1.5e-06 28.0 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 GAM26335.1 - 3.6e-07 30.0 2.5 0.00027 20.6 0.0 2.7 2 1 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 GAM26335.1 - 4.8e-05 23.1 1.6 7.5e-05 22.5 0.0 2.0 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 GAM26335.1 - 0.00085 18.9 0.1 0.0067 15.9 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 GAM26335.1 - 0.042 13.5 0.1 1.6 8.3 0.0 2.9 3 0 0 3 3 3 0 Putative esterase FAR1 PF03101.15 GAM26336.1 - 0.00028 21.5 0.2 0.00028 21.5 0.2 2.3 2 0 0 2 2 2 1 FAR1 DNA-binding domain NDUF_B8 PF05821.11 GAM26337.1 - 0.18 11.6 0.2 0.19 11.6 0.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF3623 PF12291.8 GAM26338.1 - 0.01 15.1 1.0 0.013 14.7 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) Mpv17_PMP22 PF04117.12 GAM26340.1 - 1e-14 54.5 1.7 1.9e-14 53.7 1.7 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Kinesin PF00225.23 GAM26341.1 - 1.5e-103 346.2 4.2 1.5e-103 346.2 4.2 2.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAM26341.1 - 8.5e-56 188.0 0.4 2.3e-55 186.6 0.4 1.8 1 0 0 1 1 1 1 Microtubule binding DUF816 PF05674.12 GAM26341.1 - 0.0015 18.5 0.8 0.0037 17.2 0.8 1.8 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF816) UPF0242 PF06785.11 GAM26341.1 - 0.0017 18.5 11.3 0.0038 17.3 10.8 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 GAM26341.1 - 0.019 15.2 2.4 0.14 12.5 0.4 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_16 PF13191.6 GAM26341.1 - 0.029 14.7 1.2 0.14 12.5 0.0 2.7 2 2 0 2 2 2 0 AAA ATPase domain CALCOCO1 PF07888.11 GAM26341.1 - 0.063 12.1 11.3 0.11 11.4 11.3 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tup_N PF08581.10 GAM26341.1 - 0.077 13.3 6.1 0.33 11.3 2.4 3.2 1 1 2 3 3 3 0 Tup N-terminal FAM184 PF15665.5 GAM26341.1 - 0.14 11.9 13.3 1.1 9.0 2.2 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B PI3K_P85_iSH2 PF16454.5 GAM26341.1 - 0.25 10.9 10.9 0.21 11.2 5.1 2.5 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Rx_N PF18052.1 GAM26341.1 - 0.39 11.0 5.8 0.15 12.3 1.6 2.4 2 1 0 2 2 2 0 Rx N-terminal domain Spc7 PF08317.11 GAM26341.1 - 0.48 9.2 14.9 1 8.2 2.0 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF848 PF05852.11 GAM26341.1 - 0.64 10.1 9.8 0.12 12.4 3.9 2.7 3 1 0 4 4 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4201 PF13870.6 GAM26341.1 - 1.4 8.7 14.1 7.6 6.2 14.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) CLZ PF16526.5 GAM26341.1 - 1.4 9.4 5.8 0.74 10.2 1.3 2.8 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TSC22 PF01166.18 GAM26341.1 - 1.5 9.2 10.3 0.086 13.2 2.3 3.1 3 0 0 3 3 2 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 GAM26341.1 - 1.6 8.7 13.5 1.1 9.3 4.0 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.6 GAM26341.1 - 1.9 8.7 13.0 0.21 11.8 2.9 3.0 2 1 0 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3450 PF11932.8 GAM26341.1 - 3.3 7.0 9.4 10 5.4 9.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ZapB PF06005.12 GAM26341.1 - 3.3 8.2 12.8 0.14 12.6 4.2 2.9 3 0 0 3 3 2 0 Cell division protein ZapB APG6_N PF17675.1 GAM26341.1 - 4.1 7.9 15.3 0.17 12.4 4.8 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region bZIP_1 PF00170.21 GAM26341.1 - 6.3 7.0 7.7 0.73 10.0 1.8 2.5 3 0 0 3 3 2 0 bZIP transcription factor DUF4200 PF13863.6 GAM26341.1 - 8.4 6.8 14.3 0.29 11.6 1.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.8 GAM26341.1 - 9.3 6.5 12.8 2.5 8.3 3.2 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fzo_mitofusin PF04799.13 GAM26341.1 - 9.6 5.7 7.8 2 7.9 1.6 2.5 1 1 1 2 2 2 0 fzo-like conserved region TIG PF01833.24 GAM26342.1 - 4.1e-24 84.5 49.3 2.8e-06 27.3 1.6 7.9 5 1 3 8 8 8 5 IPT/TIG domain EGF_2 PF07974.13 GAM26342.1 - 0.00022 21.5 12.5 0.00056 20.2 12.5 1.7 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 GAM26342.1 - 0.0034 17.6 9.3 0.007 16.6 9.3 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 GAM26342.1 - 0.11 13.2 7.4 0.36 11.5 7.4 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF S_locus_glycop PF00954.20 GAM26342.1 - 0.53 10.8 3.1 2.4 8.7 3.1 2.2 1 0 0 1 1 1 0 S-locus glycoprotein domain Cyclin_N PF00134.23 GAM26343.1 - 1.1e-11 44.6 0.2 1.7e-11 43.9 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAM26343.1 - 2.2e-09 37.9 0.2 5.2e-09 36.7 0.2 1.8 1 1 0 1 1 1 1 Cyclin GATA PF00320.27 GAM26344.1 - 5.1e-13 48.4 9.0 5.1e-13 48.4 9.0 2.0 2 0 0 2 2 2 1 GATA zinc finger SF-assemblin PF06705.11 GAM26344.1 - 0.0066 15.8 4.5 0.011 15.0 4.5 1.3 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF1640 PF07798.11 GAM26344.1 - 0.011 15.8 2.9 0.011 15.8 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) V-SNARE PF05008.15 GAM26344.1 - 0.09 13.2 4.8 0.27 11.6 4.8 1.8 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Mlp PF03304.13 GAM26344.1 - 0.091 13.0 4.3 0.13 12.5 2.2 2.0 2 0 0 2 2 2 0 Mlp lipoprotein family 4HB_MCP_1 PF12729.7 GAM26344.1 - 0.35 10.4 8.1 0.75 9.3 8.1 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Spc7 PF08317.11 GAM26344.1 - 1.4 7.7 11.6 0.031 13.2 4.3 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF745 PF05335.13 GAM26344.1 - 4.5 7.0 6.8 0.73 9.5 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF745) SHE3 PF17078.5 GAM26344.1 - 4.5 6.9 16.2 0.052 13.3 7.0 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 YlqD PF11068.8 GAM26344.1 - 5 7.5 11.7 0.89 9.9 1.7 2.5 2 0 0 2 2 2 0 YlqD protein Muted PF14942.6 GAM26344.1 - 5.5 7.3 12.9 0.64 10.3 4.3 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein LMBR1 PF04791.16 GAM26344.1 - 7 5.4 5.8 2 7.2 0.9 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein RhoGEF PF00621.20 GAM26345.1 - 3e-42 144.9 5.7 3e-42 144.9 5.7 2.0 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 GAM26345.1 - 3.6e-11 43.2 0.0 1.2e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 GAM26345.1 - 0.0024 17.5 0.1 0.0069 16.1 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif IQ_SEC7_PH PF16453.5 GAM26345.1 - 0.024 14.6 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 PH domain SF3A3 PF16837.5 GAM26345.1 - 0.061 13.9 1.2 0.28 11.7 0.5 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 TRAPP PF04051.16 GAM26346.1 - 3.8e-36 124.0 0.1 4.7e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DCX PF03607.17 GAM26347.1 - 1.9e-33 114.4 0.3 7.3e-16 58.0 0.0 2.3 2 0 0 2 2 2 2 Doublecortin PRCC PF10253.9 GAM26347.1 - 0.063 14.1 3.7 0.09 13.6 3.7 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Mucin PF01456.17 GAM26347.1 - 0.094 12.7 20.9 0.14 12.1 20.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 GAM26347.1 - 5.9 4.7 6.8 7.7 4.4 6.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein F-box-like PF12937.7 GAM26348.1 - 1.7e-06 27.8 0.0 4.7e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM26348.1 - 0.00074 19.3 0.1 0.0027 17.6 0.0 2.1 1 1 0 1 1 1 1 F-box domain Elongin_A PF06881.11 GAM26348.1 - 0.0023 18.4 0.2 0.0037 17.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A BTK PF00779.19 GAM26348.1 - 0.0059 16.4 1.0 0.012 15.4 1.0 1.5 1 0 0 1 1 1 1 BTK motif Mad3_BUB1_I PF08311.12 GAM26348.1 - 0.025 14.6 0.7 0.041 13.9 0.7 1.3 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Nramp PF01566.18 GAM26349.1 - 2.5e-126 421.5 16.0 2.5e-126 421.5 16.0 1.8 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Herpes_LMP1 PF05297.11 GAM26349.1 - 8.3 5.5 7.2 19 4.3 7.2 1.6 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DENN PF02141.21 GAM26350.1 - 1.3e-50 171.9 12.2 1.8e-50 171.5 9.8 2.2 2 0 0 2 2 2 1 DENN (AEX-3) domain WD40 PF00400.32 GAM26350.1 - 1.4e-40 136.5 31.7 4.1e-05 24.2 0.0 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat uDENN PF03456.18 GAM26350.1 - 1.4e-16 61.0 0.4 4.7e-16 59.3 0.4 2.0 1 0 0 1 1 1 1 uDENN domain C2 PF00168.30 GAM26350.1 - 2.9e-11 43.6 0.6 8.8e-11 42.0 0.6 1.8 1 0 0 1 1 1 1 C2 domain WD40_like PF17005.5 GAM26350.1 - 1.4e-08 34.4 4.0 0.00055 19.4 0.1 3.4 1 1 1 3 3 3 3 WD40-like domain SBF2 PF12335.8 GAM26350.1 - 3.7e-05 23.5 0.9 3.7e-05 23.5 0.9 2.6 3 0 0 3 3 2 1 Myotubularin protein Nup160 PF11715.8 GAM26350.1 - 3.8e-05 22.5 21.5 0.26 9.9 0.4 6.0 4 2 1 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAM26350.1 - 9.7e-05 22.6 4.4 0.071 13.4 0.1 4.6 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain dDENN PF03455.19 GAM26350.1 - 0.0004 20.3 1.1 0.0004 20.3 1.1 2.8 3 0 0 3 3 3 1 dDENN domain KH_2 PF07650.17 GAM26350.1 - 0.016 15.0 0.8 0.04 13.7 0.8 1.6 1 0 0 1 1 1 0 KH domain YebO PF13974.6 GAM26350.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.6 2 0 0 2 2 1 0 YebO-like protein KH_1 PF00013.29 GAM26350.1 - 0.21 11.5 1.4 0.6 10.0 1.4 1.7 1 0 0 1 1 1 0 KH domain Voltage_CLC PF00654.20 GAM26351.1 - 1.7e-88 297.3 25.0 2.3e-88 296.8 22.3 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 GAM26351.1 - 1.3e-08 35.2 4.5 0.0032 17.9 0.3 3.3 3 0 0 3 3 3 2 CBS domain DUF2660 PF10859.8 GAM26351.1 - 0.017 15.6 1.9 0.017 15.6 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) XhlA PF10779.9 GAM26351.1 - 0.032 14.4 0.3 0.11 12.7 0.3 1.9 1 0 0 1 1 1 0 Haemolysin XhlA DUF3899 PF13038.6 GAM26351.1 - 0.61 10.6 0.0 0.61 10.6 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) GATA PF00320.27 GAM26352.1 - 3.6e-14 52.1 4.2 4.7e-14 51.7 2.9 1.9 2 0 0 2 2 2 1 GATA zinc finger PI_PP_C PF18365.1 GAM26352.1 - 0.12 12.3 0.2 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain DUF3439 PF11921.8 GAM26353.1 - 0.12 12.3 11.7 0.087 12.8 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4485 PF14846.6 GAM26355.1 - 0.19 11.8 0.3 0.19 11.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) DnaT PF17948.1 GAM26356.1 - 0.0043 16.7 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 DnaT DNA-binding domain CDC45 PF02724.14 GAM26356.1 - 0.039 12.2 21.1 0.037 12.3 21.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 GAM26356.1 - 0.081 11.7 11.9 0.077 11.7 11.9 1.1 1 0 0 1 1 1 0 Presenilin PTPRCAP PF15713.5 GAM26356.1 - 0.11 12.8 19.4 0.15 12.3 19.4 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SpoIIIAH PF12685.7 GAM26356.1 - 0.15 11.8 15.9 0.2 11.4 15.9 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Zip PF02535.22 GAM26356.1 - 0.17 11.1 8.1 0.16 11.2 8.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Rrn6 PF10214.9 GAM26356.1 - 0.68 8.4 10.7 0.8 8.1 10.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Raftlin PF15250.6 GAM26356.1 - 0.77 8.4 10.7 0.84 8.3 10.7 1.1 1 0 0 1 1 1 0 Raftlin RR_TM4-6 PF06459.12 GAM26356.1 - 0.85 9.4 24.5 1.2 8.9 24.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.12 GAM26356.1 - 1.2 7.6 32.8 1.6 7.2 32.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Merozoite_SPAM PF07133.11 GAM26356.1 - 1.2 9.0 37.4 0.069 13.1 32.5 1.4 2 0 0 2 2 1 0 Merozoite surface protein (SPAM) CCDC106 PF15794.5 GAM26356.1 - 1.5 8.5 18.2 2.6 7.7 18.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DltD PF04914.12 GAM26356.1 - 2 7.7 14.8 2.9 7.2 14.8 1.3 1 0 0 1 1 1 0 DltD protein Vfa1 PF08432.10 GAM26356.1 - 2.3 8.5 30.8 0.15 12.4 25.9 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 SIR4_SID PF16991.5 GAM26356.1 - 3.7 7.6 16.2 6.1 6.9 16.2 1.4 1 0 0 1 1 1 0 Sir4 SID domain DUF908 PF06012.12 GAM26356.1 - 3.7 6.9 9.6 4.5 6.6 9.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) GAGA_bind PF06217.12 GAM26356.1 - 4.1 7.6 14.3 5.1 7.3 14.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RP-C_C PF11800.8 GAM26356.1 - 4.6 7.3 9.6 6.4 6.8 9.6 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region LAP1C PF05609.12 GAM26356.1 - 5 6.1 16.7 6 5.8 16.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 GAM26356.1 - 5.1 4.1 10.1 5.1 4.1 10.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CKAP2_C PF15297.6 GAM26356.1 - 6.2 5.8 19.1 7.6 5.5 19.1 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus MDM10 PF12519.8 GAM26356.1 - 6.2 5.6 10.9 6 5.6 10.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FGF-BP1 PF06473.12 GAM26356.1 - 6.4 6.5 16.4 11 5.8 16.4 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) NPR3 PF03666.13 GAM26356.1 - 8.4 5.1 19.7 9.7 4.9 19.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 GAM26356.1 - 8.5 4.4 29.5 10 4.2 29.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 GAM26356.1 - 8.5 5.2 12.2 11 4.9 12.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4661 PF15576.6 GAM26356.1 - 9.7 6.0 6.9 10 5.9 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) FNIP PF05725.12 GAM26357.1 - 2.5e-06 27.5 11.6 0.059 13.5 0.0 7.6 7 2 1 8 8 8 4 FNIP Repeat DC_STAMP PF07782.13 GAM26357.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 DC-STAMP-like protein Agenet PF05641.12 GAM26358.1 - 0.0021 18.5 1.1 0.33 11.5 0.1 3.0 3 0 0 3 3 3 2 Agenet domain Tudor_3 PF18115.1 GAM26358.1 - 0.038 13.8 0.2 1 9.3 0.1 2.6 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Phage_integrase PF00589.22 GAM26361.1 - 1.7e-11 44.2 0.0 3.2e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 GAM26361.1 - 0.00011 22.4 0.1 0.00027 21.2 0.1 1.6 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 GAM26361.1 - 0.0004 20.8 0.3 0.0011 19.4 0.3 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Retrotrans_gag PF03732.17 GAM26363.1 - 2.1e-05 24.7 0.0 3.8e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 GAM26363.1 - 0.0041 16.8 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type NMT1_3 PF16868.5 GAM26364.1 - 0.086 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family DUF5423 PF17461.2 GAM26364.1 - 0.6 8.9 6.8 0.87 8.4 6.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) zf-BED PF02892.15 GAM26364.1 - 1.9 8.6 5.0 1.8 8.7 0.8 2.9 3 0 0 3 3 3 0 BED zinc finger RVP PF00077.20 GAM26365.1 - 0.00019 21.7 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 GAM26365.1 - 0.0002 21.9 0.0 0.00038 21.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GAM26365.1 - 0.00054 20.5 0.2 0.0012 19.4 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 GAM26365.1 - 0.12 12.6 0.3 0.31 11.2 0.3 1.8 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GAM26366.1 - 1.1e-15 57.4 5.5 1.9e-15 56.7 4.6 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 GAM26366.1 - 2.5e-09 37.3 0.0 4.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GAM26366.1 - 0.0031 17.7 3.4 0.082 13.1 0.1 3.3 3 0 0 3 3 3 1 H2C2 zinc finger Agenet PF05641.12 GAM26368.1 - 0.016 15.7 1.0 0.076 13.5 1.0 2.3 1 1 0 1 1 1 0 Agenet domain HMG_CoA_synt_C PF08540.10 GAM26369.1 - 3.8e-94 315.4 4.0 4.7e-94 315.1 4.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 GAM26369.1 - 8.1e-89 296.1 0.6 1.2e-88 295.6 0.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Myb_Cef PF11831.8 GAM26369.1 - 0.049 13.2 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component SYF2 PF08231.12 GAM26370.1 - 1.2e-20 74.6 12.4 1.2e-20 74.6 12.4 2.2 1 1 1 2 2 2 1 SYF2 splicing factor DUF1398 PF07166.11 GAM26370.1 - 0.94 9.6 7.5 0.1 12.7 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1398) Arm PF00514.23 GAM26371.1 - 7.3e-12 44.9 16.3 0.0069 16.4 0.0 7.6 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAM26371.1 - 2e-09 37.7 0.2 0.071 13.5 0.0 4.9 3 2 0 4 4 4 3 HEAT repeats Xpo1 PF08389.12 GAM26371.1 - 0.0024 17.9 1.1 0.0024 17.9 1.1 3.6 2 1 1 3 3 3 1 Exportin 1-like protein HEAT_EZ PF13513.6 GAM26371.1 - 0.062 13.8 4.3 14 6.3 0.2 5.4 5 2 0 5 5 5 0 HEAT-like repeat V-ATPase_H_C PF11698.8 GAM26371.1 - 0.12 12.5 8.5 3.3 7.9 0.1 3.6 4 2 0 4 4 4 0 V-ATPase subunit H GMAP PF06540.11 GAM26371.1 - 0.15 12.2 0.4 20 5.3 0.0 4.0 4 0 0 4 4 4 0 Galanin message associated peptide (GMAP) Pkinase_Tyr PF07714.17 GAM26372.1 - 5.4e-34 117.6 0.0 1.3e-33 116.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM26372.1 - 3.1e-31 108.7 0.1 7.9e-31 107.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 GAM26372.1 - 1.5e-05 24.5 0.3 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SIS PF01380.22 GAM26374.1 - 8.6e-38 129.1 2.6 7.3e-21 74.4 0.2 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 GAM26374.1 - 4.9e-22 78.6 0.2 1.3e-21 77.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAM26374.1 - 8.1e-17 61.3 0.0 1.7e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain bact-PGI_C PF10432.9 GAM26374.1 - 0.0025 17.9 0.0 0.039 14.0 0.0 2.9 3 2 1 4 4 4 1 Bacterial phospho-glucose isomerase C-terminal SIS domain GATase_4 PF13230.6 GAM26374.1 - 0.014 14.3 0.2 0.16 10.9 0.1 2.2 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Prenylcys_lyase PF07156.14 GAM26375.1 - 2.2e-73 247.5 1.4 2.6e-73 247.2 1.4 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 GAM26375.1 - 4.5e-11 42.7 0.0 6.7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM26375.1 - 1.2e-10 41.5 0.1 2.7e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM26375.1 - 1.5e-05 24.8 0.0 2.9e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM26375.1 - 5.3e-05 22.6 0.1 0.00093 18.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM26375.1 - 0.003 17.5 0.1 0.01 15.9 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 GAM26375.1 - 0.0066 15.3 0.1 0.014 14.3 0.1 1.5 1 0 0 1 1 1 1 Tryptophan halogenase BPTA PF17044.5 GAM26375.1 - 0.022 14.6 1.0 0.087 12.7 0.2 2.1 1 1 1 2 2 2 0 Borrelial persistence in ticks protein A TPR_2 PF07719.17 GAM26377.1 - 0.00078 19.4 0.6 0.025 14.7 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF5383 PF17355.2 GAM26377.1 - 5.1 7.5 7.7 16 5.9 7.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5383) RlaP PF10127.9 GAM26378.1 - 1.3e-19 70.8 4.1 3.8e-11 43.1 2.3 3.3 2 2 0 2 2 2 2 RNA repair pathway DNA polymerase beta family MFS_1 PF07690.16 GAM26379.1 - 4.3e-24 85.1 18.4 4.3e-24 85.1 18.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF308 PF03729.13 GAM26379.1 - 0.77 10.1 7.0 0.41 11.0 2.3 3.0 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Mannosyl_trans4 PF15971.5 GAM26379.1 - 7.1 6.5 9.8 0.099 12.5 1.0 2.4 3 0 0 3 3 3 0 DolP-mannose mannosyltransferase TFIIA PF03153.13 GAM26380.1 - 3.9e-38 132.5 18.4 1.1e-28 101.4 18.4 2.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 GAM26380.1 - 0.076 11.6 2.5 0.079 11.5 2.5 1.2 1 0 0 1 1 1 0 Macoilin family DUF1631 PF07793.11 GAM26380.1 - 0.16 10.4 2.0 0.21 10.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) MAP65_ASE1 PF03999.12 GAM26380.1 - 0.59 8.8 8.3 0.77 8.4 8.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Tmemb_cc2 PF10267.9 GAM26380.1 - 0.71 8.9 4.8 1.3 8.1 4.8 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Pex14_N PF04695.13 GAM26380.1 - 0.95 10.1 11.9 2.4 8.8 8.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Corazonin PF17308.2 GAM26380.1 - 0.97 9.8 7.2 0.27 11.6 3.3 2.0 2 1 0 2 2 2 0 Pro-corazonin Syntaxin-6_N PF09177.11 GAM26381.1 - 2.7e-23 82.4 8.2 2.9e-23 82.3 1.4 2.3 2 0 0 2 2 2 1 Syntaxin 6, N-terminal T3SSipB PF16535.5 GAM26381.1 - 0.01 16.3 0.7 0.01 16.3 0.7 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF503 PF04456.12 GAM26381.1 - 0.016 15.0 0.4 0.065 13.1 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF503) Img2 PF05046.14 GAM26381.1 - 0.039 14.3 1.6 0.89 9.9 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Plasmid_stab_B PF10784.9 GAM26381.1 - 0.099 12.5 0.7 5.5 6.9 0.0 2.6 1 1 1 2 2 2 0 Plasmid stability protein Mga PF05043.13 GAM26381.1 - 2.3 8.8 6.4 22 5.7 0.8 3.1 2 1 1 3 3 3 0 Mga helix-turn-helix domain Phage_Gp23 PF10669.9 GAM26381.1 - 2.7 8.3 12.0 0.72 10.2 8.5 1.9 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Nucleoporin_FG2 PF15967.5 GAM26381.1 - 3.8 5.9 7.6 3.1 6.2 5.8 1.6 2 0 0 2 2 2 0 Nucleoporin FG repeated region Macro PF01661.21 GAM26382.1 - 7.7e-21 74.3 0.7 6.2e-20 71.4 0.0 2.1 2 0 0 2 2 2 1 Macro domain CRAL_TRIO_2 PF13716.6 GAM26382.1 - 1.2e-20 74.1 3.6 1.6e-20 73.7 0.5 2.3 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GAM26382.1 - 7.1e-07 29.1 0.4 2.2e-06 27.5 0.4 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain Ribosomal_L35p PF01632.19 GAM26383.1 - 0.003 18.0 1.5 0.0053 17.2 1.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L35 EF-hand_7 PF13499.6 GAM26384.1 - 2.5e-12 47.1 4.3 2e-07 31.4 1.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 GAM26384.1 - 1.5e-11 43.0 8.7 0.0014 18.0 0.3 4.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 GAM26384.1 - 9.7e-10 37.6 9.0 0.0042 16.9 0.1 5.0 4 1 1 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 GAM26384.1 - 2.3e-08 33.7 4.2 5.3e-05 23.0 0.2 3.3 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM26384.1 - 6.3e-07 28.6 11.0 0.13 11.9 0.1 5.2 5 1 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 GAM26384.1 - 4.5e-05 23.7 1.3 0.0058 16.9 0.2 2.9 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 GAM26384.1 - 0.06 13.2 0.9 4.9 7.1 0.1 3.2 4 0 0 4 4 4 0 EF hand Lon_C PF05362.13 GAM26385.1 - 5.1e-72 241.7 0.0 9.6e-72 240.8 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 GAM26385.1 - 1e-22 81.0 0.0 5.3e-22 78.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 GAM26385.1 - 8.2e-07 29.3 0.5 3.9e-06 27.1 0.0 2.3 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 GAM26385.1 - 1.1e-06 28.5 0.5 3.3e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase RuvB_N PF05496.12 GAM26385.1 - 1.4e-06 28.2 0.0 1.3e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain LON_substr_bdg PF02190.16 GAM26385.1 - 2.4e-06 27.6 3.3 1.1e-05 25.4 3.3 2.1 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 GAM26385.1 - 1e-05 25.6 0.0 4.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM26385.1 - 0.00011 22.7 0.4 0.00086 19.7 0.1 2.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_PrkA PF08298.11 GAM26385.1 - 0.00057 18.9 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 GAM26385.1 - 0.00089 19.5 1.6 0.028 14.7 0.4 3.0 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 GAM26385.1 - 0.001 18.4 0.6 0.0023 17.2 0.3 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_23 PF13476.6 GAM26385.1 - 0.002 18.6 0.0 0.002 18.6 0.0 3.1 4 0 0 4 4 3 1 AAA domain MCM PF00493.23 GAM26385.1 - 0.0053 15.9 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain AAA_14 PF13173.6 GAM26385.1 - 0.013 15.6 0.5 0.069 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM26385.1 - 0.014 15.9 0.0 0.037 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAM26385.1 - 0.027 13.8 0.1 0.073 12.4 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAM26385.1 - 0.032 13.9 0.1 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAM26385.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 GAM26385.1 - 0.058 12.7 0.3 0.52 9.6 0.4 2.4 2 0 0 2 2 2 0 KaiC AAA_6 PF12774.7 GAM26385.1 - 0.065 12.2 0.0 0.17 10.8 0.0 1.6 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region IstB_IS21 PF01695.17 GAM26385.1 - 0.082 12.6 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein SKI PF01202.22 GAM26385.1 - 0.095 12.8 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Shikimate kinase PG_binding_1 PF01471.18 GAM26385.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain AAA_33 PF13671.6 GAM26385.1 - 0.25 11.5 1.4 0.36 11.0 0.1 2.0 2 0 0 2 2 1 0 AAA domain FSA_C PF10479.9 GAM26385.1 - 5.6 5.0 11.5 9.5 4.2 11.5 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF1798 PF08807.10 GAM26386.1 - 0.0028 17.7 0.8 0.0037 17.4 0.8 1.1 1 0 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) LysE PF01810.18 GAM26386.1 - 0.01 15.3 0.1 0.011 15.3 0.1 1.1 1 0 0 1 1 1 0 LysE type translocator Ndc1_Nup PF09531.10 GAM26387.1 - 2e-08 33.4 17.4 4.2e-05 22.5 11.4 2.8 1 1 1 2 2 2 2 Nucleoporin protein Ndc1-Nup Spc24 PF08286.11 GAM26387.1 - 0.088 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DAGK_acc PF00609.19 GAM26388.1 - 1.2e-35 123.2 0.1 4.1e-28 98.7 0.1 2.4 1 1 1 2 2 2 2 Diacylglycerol kinase accessory domain C1_1 PF00130.22 GAM26388.1 - 2.8e-27 94.4 48.1 8.5e-12 44.8 12.7 3.3 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_cat PF00781.24 GAM26388.1 - 5.8e-24 84.1 0.0 9.6e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_2 PF03107.16 GAM26388.1 - 2.1e-05 24.7 34.8 0.0023 18.2 7.4 3.4 3 0 0 3 3 3 3 C1 domain Methyltransf_32 PF13679.6 GAM26389.1 - 5.1e-27 94.8 6.6 1.4e-26 93.4 6.6 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM26389.1 - 2.7e-05 24.8 0.0 7.9e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAM26389.1 - 0.00081 19.2 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 GAM26389.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM26389.1 - 0.0036 17.9 0.0 0.012 16.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM26389.1 - 0.0073 17.0 0.0 0.019 15.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM26389.1 - 0.0081 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM26389.1 - 0.014 15.0 2.0 0.66 9.5 0.0 2.6 2 1 1 3 3 3 0 Methyltransferase small domain Beta-Casp PF10996.8 GAM26389.1 - 0.06 13.6 0.6 0.27 11.6 0.1 2.3 2 1 0 2 2 2 0 Beta-Casp domain Methyltransf_18 PF12847.7 GAM26389.1 - 0.082 12.8 1.4 0.09 12.7 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain TspO_MBR PF03073.15 GAM26389.1 - 0.21 11.7 0.1 0.41 10.7 0.1 1.4 1 0 0 1 1 1 0 TspO/MBR family SUIM_assoc PF16619.5 GAM26391.1 - 1.4 9.0 11.9 3.9 7.6 4.9 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CRT-like PF08627.10 GAM26393.1 - 3.5e-143 476.6 20.4 4.2e-143 476.3 20.4 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 GAM26393.1 - 2.5e-10 40.3 2.4 2.5e-10 40.3 2.4 2.6 2 1 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 GAM26393.1 - 0.0027 17.0 7.0 0.0027 17.0 7.0 2.1 2 0 0 2 2 2 2 UAA transporter family FeoB_C PF07664.12 GAM26393.1 - 1.6 8.5 6.3 0.3 10.8 0.6 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus EamA PF00892.20 GAM26393.1 - 9.4 6.4 28.4 0.078 13.2 13.1 3.0 3 0 0 3 3 3 0 EamA-like transporter family RNA_helicase PF00910.22 GAM26394.1 - 0.042 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FNIP PF05725.12 GAM26395.1 - 2e-119 389.6 36.2 1.8e-12 47.2 0.0 12.3 9 2 3 13 13 13 13 FNIP Repeat DUF1769 PF08588.10 GAM26395.1 - 0.0027 17.9 10.1 2.6 8.3 0.0 7.1 8 2 2 10 10 10 2 Protein of unknown function (DUF1769) CENP-T_C PF15511.6 GAM26396.1 - 1.7e-08 34.5 0.0 2.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 GAM26396.1 - 2.5e-05 24.4 0.0 3.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 GAM26396.1 - 0.00014 22.2 0.2 0.00018 21.8 0.2 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GAM26396.1 - 0.00059 20.1 0.0 0.0013 18.9 0.0 1.6 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM26396.1 - 0.0015 18.9 0.1 0.0018 18.6 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 GAM26396.1 - 0.0022 18.1 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAM26396.1 - 0.0023 17.9 0.0 0.0094 15.9 0.0 1.8 1 1 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.16 GAM26396.1 - 0.063 13.3 0.1 0.13 12.3 0.1 1.5 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit GTP_EFTU PF00009.27 GAM26397.1 - 1.7e-55 187.6 0.0 2.4e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM26397.1 - 1.3e-36 125.3 0.0 3.5e-36 123.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAM26397.1 - 1.4e-14 54.2 0.1 4.4e-14 52.6 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM26397.1 - 8.9e-05 22.6 0.1 0.0017 18.4 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GAM26397.1 - 0.025 14.5 0.4 0.078 12.9 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 FlpD PF02662.16 GAM26397.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit HATPase_c_3 PF13589.6 GAM26398.1 - 3.9e-20 72.1 0.3 1.2e-19 70.5 0.3 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAM26398.1 - 1.1e-05 25.9 0.9 3.2e-05 24.4 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Filamin PF00630.19 GAM26398.1 - 0.11 13.4 2.4 2.9 8.7 0.1 4.0 4 0 0 4 4 4 0 Filamin/ABP280 repeat Carbpep_Y_N PF05388.11 GAM26399.1 - 0.076 13.6 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide ATP-synt_Eps PF04627.13 GAM26400.1 - 1.4e-19 69.7 0.0 1.7e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Rep_fac-A_3 PF08661.11 GAM26400.1 - 0.027 14.8 0.0 0.031 14.6 0.0 1.0 1 0 0 1 1 1 0 Replication factor A protein 3 EMC1_C PF07774.13 GAM26401.1 - 2e-54 184.5 0.5 2e-54 184.5 0.5 2.3 3 0 0 3 3 3 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 GAM26401.1 - 2.2e-05 24.1 4.9 0.015 14.9 0.1 4.6 3 1 0 4 4 4 1 PQQ-like domain DUF1838 PF08894.11 GAM26401.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) PP2C PF00481.21 GAM26402.1 - 4.5e-59 200.2 0.1 1.1e-58 198.9 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_6 PF13516.6 GAM26402.1 - 1e-05 25.2 10.7 0.011 15.7 0.1 6.1 6 0 0 6 6 6 2 Leucine Rich repeat PP2C_2 PF13672.6 GAM26402.1 - 3.2e-05 23.7 0.0 0.00034 20.3 0.0 2.8 2 1 0 2 2 2 1 Protein phosphatase 2C DUF4488 PF14869.6 GAM26402.1 - 0.0029 17.5 0.0 0.0098 15.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4488) LRR_1 PF00560.33 GAM26402.1 - 2.5 9.0 7.5 66 4.6 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat DNA_ligase_A_C PF04679.15 GAM26403.1 - 0.025 15.1 0.0 0.13 12.9 0.0 2.2 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region Rx_N PF18052.1 GAM26403.1 - 0.13 12.5 3.4 1.2 9.5 0.4 3.1 2 0 0 2 2 2 0 Rx N-terminal domain Nefa_Nip30_N PF10187.9 GAM26404.1 - 2.5e-13 50.3 14.4 2.5e-13 50.3 14.4 2.4 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 SRP9-21 PF05486.12 GAM26404.1 - 1.1 9.7 5.7 10 6.6 1.0 2.6 2 1 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) DUF4711 PF15829.5 GAM26404.1 - 1.2 9.0 4.1 1 9.2 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4711) API5 PF05918.11 GAM26405.1 - 1e-97 328.2 11.1 1.2e-97 327.9 11.1 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) IFN-gamma PF00714.17 GAM26405.1 - 0.039 13.8 0.1 0.098 12.5 0.1 1.6 1 0 0 1 1 1 0 Interferon gamma FANCI_S2 PF14676.6 GAM26405.1 - 0.22 11.8 3.1 0.26 11.6 0.1 2.5 3 0 0 3 3 3 0 FANCI solenoid 2 Androgen_recep PF02166.16 GAM26405.1 - 0.83 8.4 12.4 1.2 7.9 12.4 1.1 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 GAM26405.1 - 5.8 6.4 16.8 2.1 7.9 13.7 1.8 2 0 0 2 2 2 0 Spt20 family Kelch_1 PF01344.25 GAM26406.1 - 3.7e-26 90.4 13.6 2.2e-07 30.3 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 GAM26406.1 - 1.3e-25 88.9 12.2 3.9e-06 26.7 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 GAM26406.1 - 5.6e-25 86.8 11.2 1.7e-07 31.2 0.0 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 GAM26406.1 - 2.7e-22 77.8 10.6 1.5e-05 24.8 0.3 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 GAM26406.1 - 2.6e-18 65.8 15.6 7.1e-09 35.7 0.1 6.2 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM26406.1 - 3e-18 65.6 22.5 1.7e-05 24.7 0.8 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain EGF_CA PF07645.15 GAM26407.1 - 2e-09 37.5 5.8 2e-09 37.5 5.8 4.8 4 1 0 4 4 4 1 Calcium-binding EGF domain EGF PF00008.27 GAM26407.1 - 3e-05 24.2 35.1 0.062 13.6 10.9 4.0 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.7 GAM26407.1 - 0.00017 21.7 7.8 0.00017 21.7 7.8 4.1 4 1 0 4 4 4 1 EGF domain TIG PF01833.24 GAM26407.1 - 0.0002 21.4 3.8 0.0002 21.4 3.8 3.7 3 1 1 4 4 4 1 IPT/TIG domain EGF_2 PF07974.13 GAM26407.1 - 0.0013 19.0 43.0 0.049 14.0 14.0 3.8 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.7 GAM26407.1 - 0.0015 19.1 38.1 0.073 13.7 5.5 5.4 4 1 0 5 5 5 3 Human growth factor-like EGF EB PF01683.18 GAM26407.1 - 0.0017 18.6 5.3 0.0017 18.6 5.3 3.7 2 1 0 2 2 2 1 EB module cEGF PF12662.7 GAM26407.1 - 0.0044 16.9 1.3 0.0044 16.9 1.3 4.5 4 1 0 4 4 4 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 GAM26407.1 - 0.017 15.4 10.0 0.017 15.4 10.0 3.9 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site Laminin_EGF PF00053.24 GAM26407.1 - 7.3 6.8 33.5 2.1 8.6 7.1 3.5 2 1 1 3 3 3 0 Laminin EGF domain DUF1084 PF06454.11 GAM26408.1 - 1e-07 31.6 18.7 1.6e-07 31.0 18.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) PRP1_N PF06424.12 GAM26409.1 - 2.9e-49 167.3 9.2 8e-49 165.8 9.2 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 GAM26409.1 - 9.2e-31 103.9 10.5 0.005 17.6 0.0 13.3 4 3 10 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 GAM26409.1 - 3.5e-24 85.1 0.7 0.0031 18.0 0.0 8.0 6 2 1 7 7 7 5 Tetratricopeptide repeat Suf PF05843.14 GAM26409.1 - 1.2e-09 38.6 4.4 2.6e-05 24.4 0.0 4.2 3 1 2 5 5 5 2 Suppressor of forked protein (Suf) TPR_16 PF13432.6 GAM26409.1 - 2.6e-08 34.4 0.4 0.73 10.5 0.0 6.7 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM26409.1 - 4.5e-07 29.8 1.3 21 5.8 0.0 8.6 7 1 2 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM26409.1 - 1.4e-06 28.0 0.1 1.2 9.5 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM26409.1 - 1.8e-05 24.6 0.2 3 8.3 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM26409.1 - 0.00041 20.8 1.5 56 4.7 0.1 7.1 9 0 0 9 9 5 0 Tetratricopeptide repeat NRDE-2 PF08424.10 GAM26409.1 - 0.0025 17.0 0.0 0.0025 17.0 0.0 5.7 4 2 1 5 5 5 2 NRDE-2, necessary for RNA interference TPR_12 PF13424.6 GAM26409.1 - 0.0052 17.1 0.1 0.81 10.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM26409.1 - 0.024 14.5 0.0 2.9 7.9 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM26409.1 - 0.034 13.8 1.1 8.6 6.1 0.0 4.7 3 1 2 5 5 5 0 TPR repeat TPR_9 PF13371.6 GAM26409.1 - 0.049 13.8 0.0 26 5.1 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1570 PF07607.11 GAM26409.1 - 0.068 13.5 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) TPR_7 PF13176.6 GAM26409.1 - 0.071 13.2 0.0 1.8 8.8 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GAM26409.1 - 0.48 10.3 2.3 15 5.4 0.1 3.7 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal Beach PF02138.18 GAM26410.1 - 4.3e-41 141.1 0.0 1.1e-40 139.7 0.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain Pkinase PF00069.25 GAM26410.1 - 9.5e-16 57.9 0.0 1.2e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 GAM26410.1 - 1.6e-06 28.7 10.6 0.0029 18.4 0.0 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Kinase-like PF14531.6 GAM26410.1 - 0.0035 16.7 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 GAM26410.1 - 0.0074 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 GAM26410.1 - 0.017 15.4 0.1 3.3 8.1 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nop PF01798.18 GAM26411.1 - 2.6e-82 275.8 0.2 2.6e-82 275.8 0.2 3.2 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAM26411.1 - 1.4e-19 70.2 0.2 1.4e-19 70.2 0.2 3.9 2 1 2 4 4 4 1 NOP5NT (NUC127) domain DUF2104 PF09877.9 GAM26411.1 - 0.11 12.8 0.1 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) Peptidase_S9 PF00326.21 GAM26412.1 - 0.21 11.1 0.5 0.24 10.8 0.5 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S9 PF00326.21 GAM26413.1 - 0.21 11.1 0.5 0.24 10.8 0.5 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family PemK_toxin PF02452.17 GAM26414.1 - 0.0018 18.7 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system SirA PF10747.9 GAM26414.1 - 0.0043 17.4 3.6 0.0081 16.5 3.6 1.4 1 0 0 1 1 1 1 Sporulation inhibitor of replication protein SirA DUF1451 PF07295.11 GAM26414.1 - 1.5 8.9 6.9 5.6 7.0 6.9 1.8 1 1 0 1 1 1 0 Zinc-ribbon containing domain Ependymin PF00811.18 GAM26415.1 - 1.9e-06 28.1 2.2 4.4e-05 23.7 0.1 2.3 1 1 1 2 2 2 2 Ependymin LPMO_10 PF03067.15 GAM26416.1 - 0.00029 21.6 0.4 0.00043 21.0 0.4 1.3 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Gar1 PF04410.14 GAM26417.1 - 4.1e-30 104.6 4.9 6.7e-17 61.7 0.0 3.9 3 1 1 4 4 4 2 Gar1/Naf1 RNA binding region SR-25 PF10500.9 GAM26417.1 - 0.004 16.8 7.9 0.004 16.8 7.9 3.3 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein EI24 PF07264.11 GAM26418.1 - 0.018 15.3 14.1 5.2 7.3 14.1 2.2 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF5453 PF17534.2 GAM26418.1 - 1.8 8.5 7.4 0.63 10.0 0.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5453) EB1 PF03271.17 GAM26419.1 - 7.7e-12 45.3 1.6 2.7e-11 43.5 1.6 2.0 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 GAM26419.1 - 4.1e-10 39.8 0.3 1.5e-09 38.0 0.1 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain SOG2 PF10428.9 GAM26419.1 - 0.0017 17.6 6.4 0.0025 17.1 6.4 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein CH_2 PF06294.11 GAM26419.1 - 0.027 14.6 0.1 0.057 13.5 0.1 1.6 1 0 0 1 1 1 0 CH-like domain in sperm protein EF-hand_1 PF00036.32 GAM26420.1 - 1.2e-13 49.5 5.1 1.1e-06 27.7 0.1 3.3 3 0 0 3 3 3 2 EF hand WWE PF02825.20 GAM26420.1 - 1.2e-13 51.4 3.3 2.8e-13 50.3 3.3 1.7 1 0 0 1 1 1 1 WWE domain EF-hand_7 PF13499.6 GAM26420.1 - 1.3e-13 51.2 0.4 4.4e-13 49.5 0.4 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM26420.1 - 2.3e-12 45.8 0.3 2.6e-06 26.9 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GAM26420.1 - 3.7e-09 36.3 1.0 0.00045 20.0 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM26420.1 - 5.2e-09 35.2 0.5 1.8e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 GAM26420.1 - 9.3e-05 22.7 0.3 0.00081 19.7 0.0 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 GAM26420.1 - 0.00088 19.5 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain DUF1687 PF07955.11 GAM26420.1 - 1.2 9.7 4.8 0.86 10.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) DUF4598 PF15370.6 GAM26420.1 - 2.1 8.8 6.6 0.12 12.9 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) AJAP1_PANP_C PF15298.6 GAM26420.1 - 3.2 7.9 11.2 0.18 12.0 5.7 1.7 2 0 0 2 2 2 0 AJAP1/PANP C-terminus p450 PF00067.22 GAM26421.1 - 1.7e-89 300.7 0.3 1.9e-89 300.6 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 TM_helix PF05552.12 GAM26421.1 - 6.6 6.8 5.6 2.1 8.4 1.9 2.0 2 0 0 2 2 2 0 Conserved TM helix YhhN PF07947.14 GAM26422.1 - 4.8e-12 45.9 24.9 1.7e-07 31.0 2.8 2.9 2 1 1 3 3 3 2 YhhN family Orf78 PF06024.12 GAM26422.1 - 0.0035 17.6 0.9 0.0035 17.6 0.9 4.1 3 1 0 3 3 3 1 Orf78 (ac78) RIFIN PF02009.16 GAM26422.1 - 0.49 10.2 4.4 0.072 13.0 0.4 1.6 2 0 0 2 2 2 0 Rifin YlaC PF10777.9 GAM26422.1 - 3.3 7.5 7.5 2.3 8.0 5.0 2.0 2 0 0 2 2 2 0 Inner membrane protein YlaC Got1 PF04178.12 GAM26424.1 - 2.6e-30 105.1 22.7 3.4e-30 104.7 22.7 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3040 PF11239.8 GAM26424.1 - 0.36 11.1 5.6 10 6.5 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF4636 PF15468.6 GAM26424.1 - 1.8 8.2 3.2 2.8 7.6 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF4064 PF13273.6 GAM26424.1 - 9 6.6 18.4 1.4e+02 2.8 18.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) S-AdoMet_synt_C PF02773.16 GAM26427.1 - 6.6e-65 217.3 0.1 1.5e-64 216.1 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 GAM26427.1 - 2.7e-47 160.0 0.1 7e-47 158.6 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 GAM26427.1 - 4.9e-45 152.2 0.9 4.9e-45 152.2 0.9 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.17 GAM26427.1 - 0.092 11.8 0.0 0.62 9.1 0.0 1.9 2 0 0 2 2 2 0 Amidinotransferase AdoMet_Synthase PF01941.19 GAM26427.1 - 0.11 11.2 0.9 0.48 9.1 0.2 2.1 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) MSA_2 PF00985.17 GAM26427.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family CLN3 PF02487.17 GAM26428.1 - 2.6e-68 230.9 6.7 3e-68 230.7 6.7 1.0 1 0 0 1 1 1 1 CLN3 protein Ank_2 PF12796.7 GAM26429.1 - 5.8e-31 106.9 2.0 5.1e-09 36.6 0.3 4.5 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM26429.1 - 1.5e-29 101.6 15.6 9.7e-06 25.8 0.1 6.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM26429.1 - 8.1e-28 95.6 15.2 1.8e-05 25.0 0.1 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 GAM26429.1 - 7e-26 87.5 3.8 0.0018 18.6 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 GAM26429.1 - 1.6e-23 82.7 5.9 4.2e-07 30.4 0.0 5.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) DUF1843 PF08898.10 GAM26429.1 - 0.16 12.5 0.0 3.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) PseudoU_synth_2 PF00849.22 GAM26430.1 - 8.6e-18 64.9 0.0 4.2e-17 62.7 0.0 2.1 2 1 0 2 2 2 1 RNA pseudouridylate synthase MAGE_N PF12440.8 GAM26430.1 - 0.41 11.4 9.9 4.4 8.1 5.1 2.7 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Ank_2 PF12796.7 GAM26431.1 - 9.3e-09 35.8 9.9 0.18 12.4 0.6 7.7 5 2 2 8 8 8 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26431.1 - 0.00013 22.4 6.0 17 6.1 0.4 7.5 7 1 1 8 8 8 1 Ankyrin repeats (many copies) Clathrin PF00637.20 GAM26431.1 - 0.039 13.8 0.3 0.95 9.3 0.0 3.2 3 0 0 3 3 3 0 Region in Clathrin and VPS nsp8 PF08717.10 GAM26431.1 - 0.16 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 nsp8 replicase Ank_3 PF13606.6 GAM26431.1 - 0.21 12.2 10.4 2.7e+02 2.7 0.2 8.5 8 0 0 8 8 8 0 Ankyrin repeat Endotoxin_N PF03945.14 GAM26432.1 - 1.6e-32 113.0 2.1 2.5e-32 112.4 2.1 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain HAP2-GCS1 PF10699.9 GAM26433.1 - 1.1e-12 47.7 0.2 1.8e-12 47.0 0.2 1.3 1 0 0 1 1 1 1 Male gamete fusion factor Ank_2 PF12796.7 GAM26434.1 - 0.00025 21.6 3.2 19 6.0 0.0 4.6 3 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26434.1 - 0.0016 19.0 3.5 2.1 9.1 0.0 5.4 5 1 1 6 6 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM26435.1 - 8.8e-06 26.2 0.4 0.00072 20.1 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM26435.1 - 0.0046 17.4 1.0 24 5.9 0.0 5.3 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 GAM26435.1 - 0.0065 16.8 0.5 1.5 9.3 0.1 4.2 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM26435.1 - 0.02 15.5 0.5 5.6 7.7 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) GSHPx PF00255.19 GAM26436.1 - 5.9e-14 51.6 0.2 7.9e-14 51.2 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Cullin PF00888.22 GAM26437.1 - 2.5e-29 102.4 22.8 7.7e-29 100.8 22.9 1.7 1 1 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 GAM26437.1 - 5.9e-20 71.5 0.3 2.2e-19 69.7 0.3 2.1 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Kinesin PF00225.23 GAM26438.1 - 1.6e-111 372.5 1.0 1.6e-111 372.5 1.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAM26438.1 - 6.3e-34 117.1 0.3 6.3e-34 117.1 0.3 2.5 2 0 0 2 2 2 1 Microtubule binding DivIC PF04977.15 GAM26438.1 - 0.0051 16.5 4.2 0.0051 16.5 4.2 7.4 5 3 3 8 8 8 2 Septum formation initiator FAD_binding_4 PF01565.23 GAM26439.1 - 3.9e-26 91.4 1.1 5.8e-26 90.9 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Methyltransf_11 PF08241.12 GAM26439.1 - 1e-06 29.3 0.0 6.8e-06 26.7 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM26439.1 - 4.1e-06 27.4 0.0 3.3e-05 24.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM26439.1 - 8e-06 25.8 0.0 1.9e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ALO PF04030.14 GAM26439.1 - 3.5e-05 23.8 1.3 7.4e-05 22.7 0.5 1.9 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase Methyltransf_12 PF08242.12 GAM26439.1 - 0.0053 17.5 0.0 0.015 16.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAM26439.1 - 0.06 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain Peptidase_M24 PF00557.24 GAM26440.1 - 9.6e-50 169.2 0.0 1.2e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 GAM26440.1 - 9.8e-16 57.8 7.8 1.7e-15 57.0 7.8 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 GAM26440.1 - 0.0017 18.4 2.9 0.004 17.2 2.9 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 GAM26440.1 - 0.011 15.5 5.9 0.027 14.3 5.9 1.7 1 0 0 1 1 1 0 HIT zinc finger Myotub-related PF06602.14 GAM26441.1 - 1.3e-129 432.2 1.1 2.2e-129 431.4 1.1 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FERM_f0 PF16511.5 GAM26441.1 - 1.1e-06 28.9 0.0 0.21 11.9 0.0 4.8 5 0 0 5 5 5 2 N-terminal or F0 domain of Talin-head FERM DSPc PF00782.20 GAM26441.1 - 0.0045 16.8 0.0 0.018 14.9 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain GRAM PF02893.20 GAM26441.1 - 0.0096 15.8 0.0 0.039 13.8 0.0 2.0 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.6 GAM26441.1 - 0.019 15.0 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAM26441.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DIOX_N PF14226.6 GAM26442.1 - 0.00016 22.4 0.0 0.00034 21.3 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM26442.1 - 0.00017 22.0 0.0 0.00029 21.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DnaJ PF00226.31 GAM26443.1 - 9.2e-24 83.4 0.7 2.1e-23 82.2 0.7 1.7 1 0 0 1 1 1 1 DnaJ domain Ribosomal_60s PF00428.19 GAM26443.1 - 0.02 15.4 7.5 0.02 15.4 7.5 3.7 3 1 1 4 4 3 0 60s Acidic ribosomal protein DNA_pol_phi PF04931.13 GAM26443.1 - 0.07 11.2 21.5 0.13 10.4 21.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GAM26443.1 - 0.17 11.2 13.2 0.31 10.3 13.2 1.4 1 0 0 1 1 1 0 NOA36 protein TPR_8 PF13181.6 GAM26443.1 - 0.28 11.5 1.2 8.3 6.9 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Pox_Ag35 PF03286.14 GAM26443.1 - 0.42 10.4 20.0 0.067 13.0 14.4 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 GAM26443.1 - 0.77 9.3 19.7 0.029 14.0 13.7 1.8 2 0 0 2 2 2 0 PPP4R2 CDC45 PF02724.14 GAM26443.1 - 0.93 7.7 20.3 0.038 12.3 14.7 1.5 2 0 0 2 2 2 0 CDC45-like protein Merozoite_SPAM PF07133.11 GAM26443.1 - 1.1 9.2 34.7 0.028 14.4 25.0 2.5 2 1 0 2 2 2 0 Merozoite surface protein (SPAM) DUF4820 PF16091.5 GAM26443.1 - 1.8 7.9 10.1 4.1 6.7 10.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3042 PF11240.8 GAM26443.1 - 2.3 8.3 8.5 4.1 7.5 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF913 PF06025.12 GAM26443.1 - 2.8 6.8 9.6 0.27 10.2 5.1 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 GAM26443.1 - 3.1 7.2 19.4 0.13 11.7 12.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Astro_capsid_p PF12226.8 GAM26443.1 - 4.5 6.3 14.6 9 5.3 14.6 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RR_TM4-6 PF06459.12 GAM26443.1 - 4.6 7.0 17.9 0.21 11.4 11.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 GAM26443.1 - 5.4 6.1 8.1 8.4 5.5 8.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.25 GAM26444.1 - 1.8e-38 132.4 0.1 3.2e-38 131.6 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26444.1 - 1.5e-24 86.7 0.0 2.8e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 GAM26444.1 - 1.8e-14 54.0 0.3 4.6e-14 52.7 0.3 1.8 1 0 0 1 1 1 1 Ribonuclease 2-5A Kdo PF06293.14 GAM26444.1 - 0.00021 20.7 0.4 0.00045 19.6 0.4 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM26444.1 - 0.0047 16.5 0.4 0.011 15.3 0.4 1.6 1 0 0 1 1 1 1 RIO1 family Ank_2 PF12796.7 GAM26444.1 - 0.0075 16.8 0.7 0.05 14.2 0.3 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) APH PF01636.23 GAM26444.1 - 0.021 14.7 0.4 0.092 12.7 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family KIP1 PF07765.12 GAM26444.1 - 0.17 12.0 6.2 4 7.6 2.7 3.2 2 0 0 2 2 2 0 KIP1-like protein PTR2 PF00854.21 GAM26445.1 - 1.3e-100 337.0 6.2 1.3e-100 337.0 6.2 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 GAM26445.1 - 6.5e-11 41.8 19.0 8.6e-10 38.1 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 GAM26445.1 - 0.81 7.9 20.2 0.074 11.3 1.9 3.0 2 1 0 3 3 3 0 Predicted membrane protein (DUF2070) Phage_holin_3_6 PF07332.11 GAM26445.1 - 1.4 8.9 9.3 3.6 7.7 0.1 3.6 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1045 PF06299.12 GAM26447.1 - 0.0036 17.3 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1045) LigT_PEase PF02834.16 GAM26447.1 - 0.02 15.1 0.0 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 GAM26447.1 - 0.038 13.9 0.0 5.1 7.0 0.0 2.1 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily EGF_2 PF07974.13 GAM26448.1 - 0.00069 19.9 23.1 0.036 14.5 5.2 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 GAM26448.1 - 0.01 16.2 6.8 0.01 16.2 6.8 2.7 2 0 0 2 2 2 2 EGF-like domain EB PF01683.18 GAM26448.1 - 0.061 13.6 16.5 0.22 11.8 6.8 2.4 1 1 1 2 2 2 0 EB module hEGF PF12661.7 GAM26448.1 - 6.8 7.5 21.2 0.63 10.8 6.8 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF Metallothio PF00131.20 GAM26448.1 - 7.4 6.8 15.5 16 5.7 15.5 1.5 1 0 0 1 1 1 0 Metallothionein COR PF16095.5 GAM26449.1 - 8.3e-48 162.8 0.0 1.5e-47 161.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Pkinase_Tyr PF07714.17 GAM26449.1 - 2.9e-42 144.7 0.0 5e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM26449.1 - 7.4e-35 120.6 0.0 1.5e-34 119.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Roc PF08477.13 GAM26449.1 - 8.5e-21 74.4 0.2 2.7e-14 53.4 0.0 2.5 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 GAM26449.1 - 3.8e-15 55.4 24.9 9.3e-08 31.7 2.6 5.0 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAM26449.1 - 6.1e-14 51.9 32.1 6.6e-06 26.4 1.2 6.6 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) Ras PF00071.22 GAM26449.1 - 4.7e-12 45.8 0.4 1e-10 41.5 0.4 2.2 1 1 0 1 1 1 1 Ras family Myotub-related PF06602.14 GAM26449.1 - 1.9e-09 36.9 0.5 4.3e-09 35.8 0.5 1.5 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain MMR_HSR1 PF01926.23 GAM26449.1 - 0.0001 22.4 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 GAM26449.1 - 0.00038 19.9 0.1 0.02 14.3 0.1 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family TniB PF05621.11 GAM26449.1 - 0.0004 19.8 0.1 0.0009 18.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial TniB protein GTP_EFTU PF00009.27 GAM26449.1 - 0.002 17.7 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LRR_1 PF00560.33 GAM26449.1 - 0.0039 17.5 19.5 4.6 8.2 0.4 8.2 8 0 0 8 8 7 1 Leucine Rich Repeat Vps36_ESCRT-II PF11605.8 GAM26449.1 - 0.0054 16.9 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 LRR_9 PF14580.6 GAM26449.1 - 0.019 14.5 10.5 0.025 14.1 1.3 3.3 1 1 2 3 3 3 0 Leucine-rich repeat Septin PF00735.18 GAM26449.1 - 0.05 12.9 0.2 0.097 11.9 0.2 1.4 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 GAM26449.1 - 0.051 13.0 0.1 0.15 11.4 0.1 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAM26449.1 - 0.092 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 GAM26449.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain LRR_6 PF13516.6 GAM26449.1 - 0.27 11.4 14.5 9.6 6.6 0.0 7.0 8 0 0 8 8 8 0 Leucine Rich repeat DnaJ PF00226.31 GAM26450.1 - 2e-21 75.9 0.2 4.3e-21 74.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain zf-MYND PF01753.18 GAM26450.1 - 2.3e-11 43.6 13.9 2.3e-11 43.6 13.9 1.8 2 0 0 2 2 1 1 MYND finger Coilin_N PF15862.5 GAM26450.1 - 0.00023 21.0 0.6 0.00023 21.0 0.6 1.7 2 0 0 2 2 2 1 Coilin N-terminus Spt20 PF12090.8 GAM26450.1 - 0.00044 19.9 21.5 0.00084 19.0 21.5 1.4 1 0 0 1 1 1 1 Spt20 family YL1 PF05764.13 GAM26450.1 - 0.0005 20.3 3.1 0.00073 19.7 3.1 1.1 1 0 0 1 1 1 1 YL1 nuclear protein MMM1 PF10296.9 GAM26450.1 - 0.0076 15.3 2.2 0.013 14.6 2.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Connexin PF00029.19 GAM26450.1 - 0.06 13.1 4.2 0.18 11.5 4.2 1.8 1 0 0 1 1 1 0 Connexin Pex26 PF07163.12 GAM26450.1 - 0.065 12.5 3.3 0.11 11.8 3.3 1.4 1 0 0 1 1 1 0 Pex26 protein TFIIA PF03153.13 GAM26450.1 - 0.073 13.1 24.4 0.11 12.5 24.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 GAM26450.1 - 0.083 12.5 0.5 0.15 11.7 0.5 1.4 1 0 0 1 1 1 0 FAM176 family DUF2722 PF10846.8 GAM26450.1 - 0.085 11.8 21.3 0.12 11.2 21.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CPSF100_C PF13299.6 GAM26450.1 - 0.11 12.7 3.1 0.17 12.0 3.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CobT PF06213.12 GAM26450.1 - 0.19 11.1 8.0 0.28 10.6 8.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Apt1 PF10351.9 GAM26450.1 - 0.2 10.5 13.9 0.32 9.8 13.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4770 PF15994.5 GAM26450.1 - 0.23 11.7 8.6 0.46 10.7 8.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) PAT1 PF09770.9 GAM26450.1 - 0.37 9.0 20.5 0.59 8.3 20.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 G0-G1_switch_2 PF15103.6 GAM26450.1 - 0.41 11.1 3.3 1 9.9 3.3 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 AIF_C PF14721.6 GAM26450.1 - 0.53 10.7 4.3 0.13 12.6 0.7 1.8 2 0 0 2 2 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Roughex PF06020.11 GAM26450.1 - 0.65 9.0 7.4 0.99 8.4 7.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PcfK PF14058.6 GAM26450.1 - 0.66 10.2 12.8 1.3 9.3 12.8 1.5 1 0 0 1 1 1 0 PcfK-like protein Peptidase_S49_N PF08496.10 GAM26450.1 - 1.2 9.2 8.4 3.3 7.8 8.4 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SRP-alpha_N PF04086.13 GAM26450.1 - 3.6 7.4 14.0 5.3 6.9 14.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Lin-8 PF03353.15 GAM26450.1 - 3.8 7.0 19.7 6.1 6.3 19.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.13 GAM26450.1 - 6.2 6.5 10.9 9.6 5.9 10.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain EIIBC-GUT_N PF03612.14 GAM26450.1 - 7 6.3 8.2 13 5.4 8.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TMEM51 PF15345.6 GAM26450.1 - 8.9 6.1 14.2 18 5.0 14.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 PEMT PF04191.13 GAM26451.1 - 9.5e-52 173.9 23.1 2.2e-33 114.8 3.0 3.0 3 0 0 3 3 3 2 Phospholipid methyltransferase DREPP PF05558.12 GAM26451.1 - 5.2 6.9 10.5 23 4.8 11.3 1.6 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide PP2C PF00481.21 GAM26452.1 - 7.5e-53 179.8 2.1 1.2e-51 175.8 0.1 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAM26452.1 - 0.066 12.8 0.2 0.22 11.1 0.2 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C CCDC24 PF15669.5 GAM26452.1 - 2.2 8.1 11.3 0.76 9.6 2.7 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family DUF3447 PF11929.8 GAM26453.1 - 0.0078 16.2 4.3 6.6 6.8 0.1 4.4 3 1 1 4 4 4 2 Domain of unknown function (DUF3447) FNIP PF05725.12 GAM26454.1 - 1.4e-14 54.0 1.6 1.3e-09 38.1 0.0 3.7 3 1 0 3 3 3 3 FNIP Repeat CBAH PF02275.18 GAM26454.1 - 0.1 12.3 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family FNIP PF05725.12 GAM26455.1 - 1.7e-22 79.3 1.6 1.1e-12 47.9 0.0 2.8 3 0 0 3 3 3 2 FNIP Repeat NAD_kinase PF01513.21 GAM26457.1 - 1.1e-49 169.3 0.0 1.1e-49 169.3 0.0 1.5 2 0 0 2 2 2 1 ATP-NAD kinase DAGK_cat PF00781.24 GAM26457.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pex14_N PF04695.13 GAM26457.1 - 0.36 11.5 6.1 0.68 10.6 6.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SelP_N PF04592.14 GAM26457.1 - 0.48 9.8 8.1 1.2 8.5 8.2 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region HicA_toxin PF07927.12 GAM26457.1 - 0.54 10.3 0.0 0.54 10.3 0.0 2.0 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, Macoilin PF09726.9 GAM26457.1 - 1.7 7.1 8.3 2 6.8 8.3 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 GAM26457.1 - 5.4 5.7 7.2 7.3 5.2 7.2 1.1 1 0 0 1 1 1 0 Presenilin Tmemb_cc2 PF10267.9 GAM26457.1 - 7.6 5.6 9.2 11 5.0 9.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Arf PF00025.21 GAM26458.1 - 1.2e-36 125.8 0.0 1.3e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM26458.1 - 8.2e-10 39.0 0.0 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAM26458.1 - 1.1e-08 34.7 0.1 1.4e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM26458.1 - 1.7e-06 27.6 0.0 2.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM26458.1 - 4.8e-06 26.6 0.0 7.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 GAM26458.1 - 1.1e-05 25.1 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAM26458.1 - 2.8e-05 23.5 2.0 0.044 12.9 0.4 2.4 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 GAM26458.1 - 0.027 14.0 0.0 0.37 10.3 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 GAM26458.1 - 0.042 13.5 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PB1 PF00564.24 GAM26460.1 - 0.0011 18.9 0.3 0.0025 17.7 0.3 1.6 1 0 0 1 1 1 1 PB1 domain SGP PF17228.2 GAM26460.1 - 7.9 7.4 8.0 0.29 12.0 0.7 2.3 2 0 0 2 2 2 0 Sulphur globule protein Membrane_bind PF14564.6 GAM26461.1 - 2.4e-36 124.5 0.0 4.3e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Membrane binding Crystall_3 PF08964.10 GAM26461.1 - 5.3e-20 71.4 0.0 9e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Beta/Gamma crystallin Ribosomal_S10 PF00338.22 GAM26462.1 - 1.8e-23 82.6 0.1 2.3e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e C2 PF00168.30 GAM26464.1 - 1.8e-08 34.6 0.0 4.9e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain HATPase_c PF02518.26 GAM26465.1 - 5.1e-30 104.3 0.1 1.2e-29 103.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CHASE PF03924.13 GAM26465.1 - 9.4e-26 90.9 0.0 2.2e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 CHASE domain Response_reg PF00072.24 GAM26465.1 - 5e-23 81.4 0.0 2.2e-22 79.3 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAM26465.1 - 3.6e-20 71.8 0.5 1.1e-19 70.2 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 GAM26465.1 - 1.6e-07 31.5 0.0 3.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 GAM26465.1 - 0.025 14.4 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 GAM26465.1 - 0.029 14.6 0.1 0.082 13.2 0.1 1.8 1 0 0 1 1 1 0 PAS domain FMN_red PF03358.15 GAM26466.1 - 3.9e-29 101.4 0.0 5.1e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAM26466.1 - 2.9e-07 30.4 0.0 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF2325 PF10087.9 GAM26466.1 - 0.064 13.4 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) preATP-grasp_3 PF18301.1 GAM26466.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 pre ATP-grasp 3 domain Aminotran_3 PF00202.21 GAM26467.1 - 1.4e-115 386.3 0.0 1.6e-115 386.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Asp PF00026.23 GAM26468.1 - 8.2e-13 48.4 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 GAM26468.1 - 1e-12 48.1 1.9 1.2e-12 47.9 0.0 2.1 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal TSP_1 PF00090.19 GAM26468.1 - 0.0023 18.1 17.1 0.0032 17.7 5.0 4.5 4 1 0 4 4 4 2 Thrombospondin type 1 domain F-box_5 PF18511.1 GAM26470.1 - 0.12 12.0 0.4 0.2 11.2 0.4 1.4 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 GAM26470.1 - 0.13 12.2 0.1 0.32 10.9 0.1 1.7 1 0 0 1 1 1 0 F-box-like DUF4212 PF13937.6 GAM26472.1 - 0.019 15.3 8.4 0.65 10.4 6.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Esterase_phd PF10503.9 GAM26473.1 - 4.1e-10 39.5 1.7 4e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S9 PF00326.21 GAM26473.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_S4e PF00900.20 GAM26474.1 - 1.6e-28 98.4 0.2 3.3e-28 97.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 GAM26474.1 - 2.3e-18 66.0 8.2 4.8e-18 65.0 8.2 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 GAM26474.1 - 1.1e-17 63.4 0.1 1.7e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 GAM26474.1 - 2.1e-10 40.1 0.0 3.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 GAM26474.1 - 9.4e-05 22.2 0.1 9.4e-05 22.2 0.1 2.3 3 0 0 3 3 3 1 KOW motif Pkinase PF00069.25 GAM26476.1 - 1.4e-37 129.5 0.0 1.9e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26476.1 - 6.6e-27 94.4 0.0 9.7e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 GAM26476.1 - 3.5e-17 62.8 0.3 6.9e-17 61.8 0.3 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A APH PF01636.23 GAM26476.1 - 3.3e-05 23.9 0.1 0.14 12.0 0.6 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 GAM26476.1 - 0.0079 15.8 0.3 0.036 13.7 0.1 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 GAM26476.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM26476.1 - 0.035 12.9 0.2 1.7 7.4 0.0 2.5 3 0 0 3 3 3 0 Fungal protein kinase BTB PF00651.31 GAM26477.1 - 1.4e-22 80.0 0.4 2.8e-21 75.8 0.0 3.0 2 1 1 3 3 3 1 BTB/POZ domain DUF572 PF04502.13 GAM26477.1 - 0.38 10.3 16.2 0.67 9.5 16.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) CBFD_NFYB_HMF PF00808.23 GAM26478.1 - 4.4e-27 94.2 1.2 6.3e-27 93.7 1.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM26478.1 - 7.7e-05 23.1 0.1 7.7e-05 23.1 0.1 2.3 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAM26478.1 - 0.00031 20.8 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 GAM26478.1 - 0.0036 17.3 0.1 0.0058 16.6 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF3439 PF11921.8 GAM26478.1 - 0.0072 16.3 5.9 0.0072 16.3 5.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Bromo_TP PF07524.13 GAM26478.1 - 0.055 13.5 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF908 PF06012.12 GAM26478.1 - 0.39 10.1 7.5 0.49 9.8 7.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) VIT PF08487.10 GAM26479.1 - 2.5e-32 111.4 0.5 2.5e-32 111.4 0.5 4.2 2 1 2 4 4 4 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 GAM26479.1 - 5.9e-27 94.5 0.0 5.9e-27 94.5 0.0 2.8 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 GAM26479.1 - 4.1e-13 50.0 0.0 4.1e-13 50.0 0.0 2.8 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM26479.1 - 1.3e-09 38.7 0.0 1.3e-09 38.7 0.0 3.5 3 1 0 3 3 3 1 von Willebrand factor type A domain VIT_2 PF13757.6 GAM26479.1 - 9.3e-05 22.2 0.0 0.00033 20.5 0.0 2.0 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Glyco_transf_41 PF13844.6 GAM26479.1 - 4.4 5.6 17.1 11 4.3 17.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 41 FUSC PF04632.12 GAM26479.1 - 5.4 5.4 11.7 8.9 4.7 11.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nop53 PF07767.11 GAM26479.1 - 8 5.7 32.8 0.22 10.9 26.4 1.6 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) 7tm_3 PF00003.22 GAM26480.1 - 3.1e-21 76.2 28.5 3.1e-21 76.2 28.5 1.9 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Serglycin PF04360.12 GAM26480.1 - 0.44 10.5 5.3 0.25 11.3 2.6 1.9 2 0 0 2 2 2 0 Serglycin DUF4834 PF16118.5 GAM26481.1 - 0.15 13.1 2.5 0.29 12.1 2.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DUF5383 PF17355.2 GAM26481.1 - 0.85 10.0 3.9 0.37 11.2 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Pkinase PF00069.25 GAM26482.1 - 2.8e-62 210.5 0.0 3.8e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26482.1 - 5.3e-40 137.3 0.0 1e-39 136.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM26482.1 - 7.4e-07 28.3 0.2 2.7e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM26482.1 - 9.8e-07 28.0 3.2 2.8e-06 26.5 3.3 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAM26482.1 - 0.00088 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Macoilin PF09726.9 GAM26482.1 - 0.1 11.1 9.6 0.12 10.9 9.6 1.2 1 0 0 1 1 1 0 Macoilin family APH PF01636.23 GAM26482.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Presenilin PF01080.17 GAM26482.1 - 2.2 7.0 5.5 3.7 6.2 5.5 1.3 1 0 0 1 1 1 0 Presenilin CS PF04969.16 GAM26483.1 - 1.1e-07 32.8 0.1 1.6e-07 32.2 0.1 1.3 1 0 0 1 1 1 1 CS domain Forkhead_N PF08430.12 GAM26483.1 - 0.035 14.7 10.8 0.052 14.2 10.8 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Keratin_2_head PF16208.5 GAM26483.1 - 0.17 12.0 21.6 0.25 11.5 21.6 1.2 1 0 0 1 1 1 0 Keratin type II head PAP2 PF01569.21 GAM26484.1 - 3.9e-21 75.2 2.2 3.9e-21 75.2 2.2 2.2 1 1 1 2 2 2 2 PAP2 superfamily DUF805 PF05656.14 GAM26484.1 - 0.083 13.3 12.0 0.61 10.5 12.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Spc7 PF08317.11 GAM26484.1 - 0.26 10.1 7.8 0.36 9.6 7.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HlyD_2 PF12700.7 GAM26484.1 - 8.8 4.9 18.5 13 4.4 18.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein ATP12 PF07542.11 GAM26485.1 - 1.6e-28 99.3 0.0 3.2e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Pkinase PF00069.25 GAM26486.1 - 1.8e-07 30.8 0.1 3.4e-07 29.9 0.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26486.1 - 3.5e-05 23.2 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM26486.1 - 0.046 13.0 0.4 0.15 11.4 0.1 1.8 2 0 0 2 2 2 0 Kinase-like Mad3_BUB1_I PF08311.12 GAM26487.1 - 3.5e-39 133.6 0.2 6.1e-39 132.8 0.2 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 MIT PF04212.18 GAM26487.1 - 0.025 14.6 1.1 0.057 13.5 1.1 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mad3_BUB1_I_2 PF17014.5 GAM26487.1 - 0.048 13.8 0.5 0.081 13.0 0.5 1.3 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein EamA PF00892.20 GAM26488.1 - 2.8e-13 50.2 38.8 1.2e-07 32.0 15.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 GAM26488.1 - 4.9e-10 39.2 30.1 7.1e-10 38.6 30.1 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 GAM26488.1 - 8.6e-08 31.9 31.2 1.3e-07 31.3 31.2 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family Pox_A14 PF05767.12 GAM26488.1 - 0.025 14.7 1.0 0.025 14.7 1.0 4.0 3 2 0 3 3 3 0 Poxvirus virion envelope protein A14 Tmemb_185A PF10269.9 GAM26488.1 - 0.38 10.4 23.5 0.097 12.3 18.1 2.5 1 1 1 2 2 2 0 Transmembrane Fragile-X-F protein IBR PF01485.21 GAM26489.1 - 3.6e-07 30.3 41.5 1.2e-06 28.7 9.6 4.4 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 GAM26489.1 - 1.7e-05 24.6 4.2 1.7e-05 24.6 4.2 4.4 5 0 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM26489.1 - 2e-05 24.4 8.1 2e-05 24.4 8.1 4.9 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM26489.1 - 3.3e-05 23.8 7.1 3.3e-05 23.8 7.1 3.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAM26489.1 - 0.00021 21.6 7.8 0.00021 21.6 7.8 3.8 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.6 GAM26489.1 - 0.0022 17.8 6.3 0.0022 17.8 6.3 4.7 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM26489.1 - 0.0099 15.8 8.2 0.0099 15.8 8.2 3.7 3 1 0 3 3 3 2 zinc-RING finger domain zf-RING_11 PF17123.5 GAM26489.1 - 2.1 8.2 18.7 0.047 13.4 5.4 2.9 2 0 0 2 2 2 0 RING-like zinc finger RCC1 PF00415.18 GAM26490.1 - 5.2e-20 71.8 0.8 1.3e-09 38.5 0.0 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos PF03372.23 GAM26490.1 - 2.9e-18 66.3 0.1 3.8e-17 62.6 0.0 2.3 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RCC1_2 PF13540.6 GAM26490.1 - 2.4e-05 24.0 1.4 0.0048 16.7 0.0 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 GAM26491.1 - 1.8e-43 146.9 6.4 4.1e-14 52.9 0.2 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM26491.1 - 1.2e-28 98.2 23.2 7.4e-09 35.2 0.1 6.3 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat CENP-S PF15630.6 GAM26492.1 - 4.4e-21 75.0 0.1 8.8e-21 74.1 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAM26492.1 - 1.2e-06 28.6 0.5 3.1e-06 27.3 0.2 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 GAM26492.1 - 0.0021 18.4 0.1 0.0021 18.4 0.1 3.3 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 GAM26492.1 - 0.017 15.3 0.1 0.036 14.2 0.1 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) MID_MedPIWI PF18296.1 GAM26492.1 - 0.019 14.8 5.9 0.014 15.2 4.0 1.8 1 1 1 2 2 2 0 MID domain of medPIWI IHABP4_N PF16174.5 GAM26492.1 - 0.083 13.5 8.1 0.16 12.6 8.1 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4551 PF15087.6 GAM26492.1 - 0.14 11.0 9.3 0.16 10.8 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Rtf2 PF04641.12 GAM26492.1 - 1.2 8.5 12.4 2.4 7.5 12.4 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger SDA1 PF05285.12 GAM26493.1 - 2.9e-70 237.5 47.8 2.9e-70 237.5 47.8 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 GAM26493.1 - 7.7e-20 71.0 0.3 2.5e-19 69.3 0.3 2.0 1 0 0 1 1 1 1 NUC130/3NT domain SUA5 PF03481.13 GAM26493.1 - 0.022 15.3 0.3 0.022 15.3 0.3 2.8 3 1 0 3 3 3 0 Putative GTP-binding controlling metal-binding ASH PF15780.5 GAM26493.1 - 0.92 9.8 4.0 0.77 10.0 1.5 2.0 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MMTV_SAg PF01054.17 GAM26494.1 - 0.53 9.8 6.9 0.93 9.0 0.3 2.9 2 1 0 3 3 3 0 Mouse mammary tumour virus superantigen BolA PF01722.18 GAM26495.1 - 1.6e-29 102.0 0.3 1.9e-29 101.7 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein ECH_1 PF00378.20 GAM26496.1 - 1.6e-20 73.5 0.0 1.9e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM26496.1 - 1.3e-10 41.4 0.0 1.4e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAM26497.1 - 2.7e-27 95.7 0.0 3.2e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM26497.1 - 1.1e-08 35.0 0.1 1.3e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase OAS1_C PF10421.9 GAM26498.1 - 1.4e-17 63.8 1.9 1.4e-17 63.8 1.9 1.8 2 0 0 2 2 2 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NTP_transf_2 PF01909.23 GAM26498.1 - 0.00012 22.3 0.0 0.00024 21.3 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain NPV_P10 PF05531.12 GAM26498.1 - 0.089 13.3 1.4 0.19 12.2 0.1 2.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein YL1_C PF08265.11 GAM26498.1 - 0.11 12.3 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain MOR2-PAG1_N PF14222.6 GAM26500.1 - 3.2e-95 320.2 0.9 3.2e-95 320.2 0.9 2.2 3 0 0 3 3 3 1 Cell morphogenesis N-terminal MOR2-PAG1_mid PF14228.6 GAM26500.1 - 1.8e-75 254.4 10.6 4.3e-29 100.9 2.8 3.1 1 1 1 3 3 3 3 Cell morphogenesis central region MOR2-PAG1_C PF14225.6 GAM26500.1 - 2.8e-40 138.8 0.9 1.4e-39 136.5 0.0 2.7 3 0 0 3 3 3 1 Cell morphogenesis C-terminal DUF5415 PF17436.2 GAM26500.1 - 0.15 12.2 0.0 0.5 10.5 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5415) Aminotran_5 PF00266.19 GAM26501.1 - 3.4e-90 302.7 0.0 4.1e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAM26501.1 - 1.3e-08 34.4 0.0 1.8e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAM26501.1 - 4.4e-07 29.6 0.1 7.1e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GAM26501.1 - 0.0022 16.6 0.0 0.0032 16.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 GAM26501.1 - 0.0082 14.9 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain PWWP PF00855.17 GAM26502.1 - 1.6e-07 31.6 4.2 1.8e-07 31.5 0.0 2.9 3 0 0 3 3 3 1 PWWP domain COPIIcoated_ERV PF07970.12 GAM26503.1 - 3.2e-82 275.7 0.6 4.4e-82 275.2 0.6 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAM26503.1 - 5.5e-29 100.4 0.4 1.2e-27 96.1 0.0 2.3 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SH3_1 PF00018.28 GAM26504.1 - 1.1e-22 79.3 1.6 1e-10 41.1 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 GAM26504.1 - 3.3e-21 74.7 1.3 1.3e-10 40.8 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 GAM26504.1 - 7.6e-18 64.1 1.4 2.3e-08 33.8 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain Glutaminase PF04960.15 GAM26504.1 - 2e-05 24.0 0.0 0.00011 21.4 0.0 2.0 1 1 0 1 1 1 1 Glutaminase CS PF04969.16 GAM26504.1 - 0.00048 21.1 0.0 0.0012 19.8 0.0 1.7 1 0 0 1 1 1 1 CS domain DUF1115 PF06544.12 GAM26505.1 - 1e-39 135.9 0.0 1e-39 135.9 0.0 2.4 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) PRP3 PF08572.10 GAM26505.1 - 8e-24 84.6 3.8 8e-24 84.6 3.8 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) Abhydrolase_1 PF00561.20 GAM26506.1 - 9.9e-22 77.8 0.0 1.2e-17 64.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM26506.1 - 1.4e-20 74.8 0.1 3.9e-20 73.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM26506.1 - 1e-13 51.2 0.0 8.2e-11 41.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAM26506.1 - 0.00015 21.6 0.0 0.0045 16.8 0.0 2.3 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 GAM26506.1 - 0.00093 19.1 0.0 0.0032 17.4 0.0 1.9 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 GAM26506.1 - 0.0038 17.0 0.0 0.031 14.0 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 GAM26506.1 - 0.006 15.9 0.0 0.31 10.3 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 GAM26506.1 - 0.021 14.9 0.0 0.056 13.5 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain DUF676 PF05057.14 GAM26506.1 - 0.022 14.3 0.1 0.053 13.0 0.1 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 GAM26506.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF4905 PF16248.5 GAM26506.1 - 0.094 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) AhpC-TSA PF00578.21 GAM26507.1 - 1.8e-29 102.1 0.0 2.4e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAM26507.1 - 1.7e-08 34.3 0.0 2.1e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GAM26507.1 - 2.5e-06 27.2 0.1 9.1e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin MRP-S28 PF10213.9 GAM26508.1 - 2.2e-11 44.2 1.4 5.1e-11 43.1 0.2 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein RF-1 PF00472.20 GAM26508.1 - 0.018 15.0 0.1 0.07 13.1 0.1 2.0 1 0 0 1 1 1 0 RF-1 domain Babuvirus_MP PF07234.11 GAM26508.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Movement and RNA silencing protein Med3 PF11593.8 GAM26508.1 - 1.7 7.7 13.8 3.3 6.8 13.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RAP1 PF07218.11 GAM26508.1 - 3.5 5.8 7.9 6.9 4.8 7.9 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FSA_C PF10479.9 GAM26508.1 - 4 5.5 10.7 5.8 4.9 10.7 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PTPS PF01242.19 GAM26509.1 - 0.017 15.1 3.5 2.8 7.9 0.4 2.6 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase RabGAP-TBC PF00566.18 GAM26510.1 - 2.7e-44 151.4 0.9 2.7e-44 151.4 0.9 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain APG6_N PF17675.1 GAM26510.1 - 0.0053 17.3 10.7 0.016 15.7 10.7 1.8 1 0 0 1 1 1 1 Apg6 coiled-coil region Rootletin PF15035.6 GAM26510.1 - 0.024 14.7 13.1 0.065 13.3 13.1 1.7 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion NYD-SP28_assoc PF14775.6 GAM26510.1 - 0.3 11.2 5.8 0.83 9.8 5.8 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF4200 PF13863.6 GAM26510.1 - 0.51 10.8 13.1 1.1 9.6 13.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) KASH_CCD PF14662.6 GAM26510.1 - 0.58 10.0 16.0 1.9 8.3 16.0 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 GAM26510.1 - 0.6 10.2 11.1 1.4 8.9 11.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 GAM26510.1 - 0.69 10.3 10.7 3 8.3 10.7 2.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) COG2 PF06148.11 GAM26510.1 - 0.97 9.5 6.3 2.1 8.4 6.3 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 GAM26510.1 - 1.2 9.9 12.1 7.3 7.3 10.9 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Cnn_1N PF07989.11 GAM26510.1 - 2.5 8.3 12.5 0.41 10.8 6.9 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 GAM26510.1 - 2.7 7.8 8.6 2.2 8.1 5.0 2.3 1 1 1 2 2 2 0 Septum formation initiator Adap_comp_sub PF00928.21 GAM26511.1 - 1.4e-77 260.6 0.1 1.7e-77 260.4 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAM26511.1 - 0.0015 18.5 0.1 0.0022 17.9 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain bZIP_1 PF00170.21 GAM26512.1 - 5e-14 52.1 6.9 5.5e-14 52.0 5.7 1.7 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAM26512.1 - 9e-12 44.9 2.9 2e-11 43.8 2.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Shugoshin_N PF07558.11 GAM26512.1 - 0.0019 18.0 0.1 0.0048 16.7 0.1 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region XPC-binding PF09280.11 GAM26512.1 - 0.0021 17.7 0.2 0.0052 16.5 0.2 1.6 1 0 0 1 1 1 1 XPC-binding domain bZIP_Maf PF03131.17 GAM26512.1 - 0.0042 17.6 5.0 0.0042 17.6 5.0 2.1 1 1 1 2 2 2 1 bZIP Maf transcription factor GIT_CC PF16559.5 GAM26512.1 - 0.0053 16.6 2.1 0.01 15.7 0.2 2.5 3 0 0 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor HAP1_N PF04849.13 GAM26512.1 - 0.0062 15.8 4.7 0.014 14.6 4.7 1.5 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF648 PF04890.13 GAM26512.1 - 0.014 15.2 0.7 0.026 14.3 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF648) CENP-F_leu_zip PF10473.9 GAM26512.1 - 0.023 14.7 4.3 0.04 14.0 4.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 GAM26512.1 - 0.066 13.7 0.2 0.066 13.7 0.2 2.3 3 0 0 3 3 2 0 Cell division protein ZapB TMCO5 PF14992.6 GAM26512.1 - 0.4 10.2 5.5 0.64 9.5 5.5 1.3 1 0 0 1 1 1 0 TMCO5 family Cnn_1N PF07989.11 GAM26512.1 - 0.41 10.8 4.1 0.094 12.9 0.7 1.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 AROS PF15684.5 GAM26512.1 - 0.86 10.2 5.9 1.9 9.0 5.9 1.5 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Patatin PF01734.22 GAM26513.1 - 6.6e-17 62.4 1.4 1.1e-16 61.6 1.4 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.22 GAM26514.1 - 6.5e-14 52.6 1.9 1.3e-13 51.6 1.9 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase Asn_synthase PF00733.21 GAM26515.1 - 1e-29 104.4 0.2 7.2e-20 71.9 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase QueC PF06508.13 GAM26515.1 - 0.00054 19.5 0.0 0.0024 17.4 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC DZR PF12773.7 GAM26515.1 - 0.0016 18.4 0.2 0.0054 16.7 0.0 2.1 2 0 0 2 2 2 1 Double zinc ribbon Auto_anti-p27 PF06677.12 GAM26515.1 - 1.2 9.3 3.9 2.3 8.4 1.5 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Patatin PF01734.22 GAM26516.1 - 4.3e-16 59.7 0.3 7.8e-16 58.9 0.3 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Kelch_6 PF13964.6 GAM26517.1 - 2.7e-10 40.1 2.8 0.016 15.5 0.1 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 GAM26517.1 - 4.5e-06 26.1 4.5 0.07 12.7 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAM26517.1 - 1.1e-05 25.3 8.3 2.4 8.3 0.0 6.0 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM26517.1 - 5.6e-05 22.9 0.4 2.9 8.0 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 GAM26517.1 - 0.033 14.2 10.0 0.73 9.9 0.3 3.6 3 0 0 3 3 3 0 Kelch motif DUF4847 PF16139.5 GAM26517.1 - 0.036 14.0 0.4 0.085 12.8 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4847) SDP_N PF12278.8 GAM26517.1 - 0.052 13.7 1.3 0.065 13.4 0.1 1.7 2 0 0 2 2 2 0 Sex determination protein N terminal Pkinase_Tyr PF07714.17 GAM26519.1 - 2e-54 184.6 0.0 3.1e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM26519.1 - 1.8e-51 175.0 0.0 3.5e-51 174.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 GAM26519.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_E_B PF04042.16 GAM26521.1 - 2.2e-48 164.4 0.7 3.6e-48 163.7 0.4 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 GAM26521.1 - 4.4e-10 39.7 0.1 1.1e-09 38.4 0.1 1.7 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal BRO1 PF03097.18 GAM26522.1 - 7.9e-35 120.4 1.1 1.3e-34 119.7 0.0 1.7 1 1 1 2 2 2 1 BRO1-like domain RNA_pol_Rpc4 PF05132.14 GAM26522.1 - 8.7e-05 23.0 9.9 0.00014 22.3 0.5 2.3 2 0 0 2 2 2 1 RNA polymerase III RPC4 YL1 PF05764.13 GAM26522.1 - 0.0012 19.1 10.4 0.0012 19.1 10.4 2.1 2 0 0 2 2 2 1 YL1 nuclear protein RRN3 PF05327.11 GAM26522.1 - 0.0037 15.9 12.1 0.0037 15.9 12.1 1.7 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 GAM26522.1 - 0.0041 15.5 12.2 0.0041 15.5 12.2 2.1 2 0 0 2 2 2 1 CDC45-like protein BUD22 PF09073.10 GAM26522.1 - 0.0047 16.3 10.9 0.0047 16.3 10.9 2.2 2 0 0 2 2 2 1 BUD22 RLL PF10036.9 GAM26522.1 - 0.34 10.7 11.3 0.019 14.8 2.1 2.8 3 0 0 3 3 3 0 RNA transcription, translation and transport factor protein DDHD PF02862.17 GAM26522.1 - 0.38 10.9 6.4 1.2 9.2 0.5 2.3 2 0 0 2 2 2 0 DDHD domain Pes-10 PF07149.11 GAM26522.1 - 1 8.4 12.0 2.1 7.3 12.0 1.5 1 0 0 1 1 1 0 Pes-10 SDA1 PF05285.12 GAM26522.1 - 1.1 8.6 29.1 0.02 14.3 17.1 2.2 2 0 0 2 2 2 0 SDA1 Sigma70_ner PF04546.13 GAM26522.1 - 1.4 8.8 21.1 0.085 12.7 12.0 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Vfa1 PF08432.10 GAM26522.1 - 2.7 8.3 26.1 0.21 11.9 13.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 GAM26522.1 - 3.5 5.7 28.0 0.0076 14.5 16.2 1.9 2 0 0 2 2 2 0 Nop14-like family Connexin PF00029.19 GAM26522.1 - 6.4 6.5 6.6 0.79 9.4 0.6 2.1 2 0 0 2 2 2 0 Connexin Zip PF02535.22 GAM26522.1 - 8.2 5.5 8.2 0.23 10.7 0.4 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 GAM26522.1 - 9.8 5.9 17.2 0.31 10.8 4.9 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Spec3 PF15795.5 GAM26523.1 - 1.5e-08 35.0 17.7 0.00071 20.1 1.9 2.0 1 1 1 2 2 2 2 Ectodermal ciliogenesis protein RhoGAP PF00620.27 GAM26524.1 - 1.4e-26 93.2 1.0 2.2e-26 92.5 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain Motile_Sperm PF00635.26 GAM26524.1 - 0.043 13.7 0.2 0.14 12.0 0.2 1.8 2 0 0 2 2 2 0 MSP (Major sperm protein) domain Helicase_C PF00271.31 GAM26525.1 - 9.1e-19 67.9 0.5 2.7e-18 66.3 0.5 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM26525.1 - 2.7e-18 66.6 0.0 2.7e-18 66.6 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM26525.1 - 2.2e-15 56.9 0.0 3.5e-14 53.0 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase FANCM-MHF_bd PF16783.5 GAM26525.1 - 2.7e-06 27.4 0.4 1.5e-05 25.0 0.1 2.4 2 0 0 2 2 2 1 FANCM to MHF binding domain Helicase_C_2 PF13307.6 GAM26525.1 - 0.34 11.1 0.0 0.34 11.1 0.0 3.1 3 1 1 4 4 4 0 Helicase C-terminal domain SPX PF03105.19 GAM26526.1 - 0.13 12.2 22.9 0.57 10.0 7.1 2.4 2 0 0 2 2 2 0 SPX domain Presenilin PF01080.17 GAM26526.1 - 8.3 5.1 13.0 0.84 8.3 0.5 2.3 2 0 0 2 2 2 0 Presenilin Pyrid_oxidase_2 PF13883.6 GAM26527.1 - 8.4e-09 35.6 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 GAM26527.1 - 1.3e-08 35.3 0.0 3.3e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Myb_DNA-binding PF00249.31 GAM26528.1 - 1.4e-12 47.6 0.0 2.2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cation_ATPase_C PF00689.21 GAM26529.1 - 3.8e-47 160.3 9.7 9.9e-47 159.0 7.3 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAM26529.1 - 8.5e-37 126.4 0.7 8.5e-37 126.4 0.7 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAM26529.1 - 5.1e-23 81.0 0.0 1.1e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM26529.1 - 2.3e-16 60.7 0.1 6.5e-16 59.2 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM26529.1 - 2.7e-15 55.8 0.4 5.5e-14 51.6 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM26529.1 - 0.00053 19.8 2.9 0.079 12.7 0.2 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Colicin_im PF03857.13 GAM26529.1 - 0.00059 19.8 2.5 0.0017 18.3 2.5 1.7 1 0 0 1 1 1 1 Colicin immunity protein DUF5353 PF17304.2 GAM26529.1 - 0.13 12.0 0.6 16 5.3 0.2 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5353) HAD PF12710.7 GAM26529.1 - 0.19 12.1 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase EptA_B_N PF08019.12 GAM26529.1 - 0.56 10.1 9.5 3.3 7.6 0.2 3.3 3 1 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB DUF3792 PF12670.7 GAM26529.1 - 1.5 9.0 9.1 0.27 11.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) V-ATPase_H_N PF03224.14 GAM26531.1 - 1.1e-57 195.8 1.2 1.1e-57 195.8 1.2 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 GAM26531.1 - 4.3e-42 142.9 5.9 3.3e-41 140.1 0.6 2.6 2 1 1 3 3 3 1 V-ATPase subunit H Arm_2 PF04826.13 GAM26531.1 - 6.3e-05 22.6 0.3 0.0034 16.9 0.0 2.3 2 0 0 2 2 2 1 Armadillo-like Arm PF00514.23 GAM26531.1 - 0.0017 18.3 0.0 16 5.7 0.0 4.0 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAM26531.1 - 0.041 14.3 0.0 3.2 8.2 0.0 3.3 3 1 0 3 3 3 0 HEAT repeats DUF3361 PF11841.8 GAM26531.1 - 0.067 13.1 1.4 0.26 11.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) NurA PF09376.10 GAM26531.1 - 0.12 12.1 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 NurA domain Cnd1 PF12717.7 GAM26531.1 - 0.15 12.1 1.7 12 6.0 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Glyco_hydro_18 PF00704.28 GAM26532.1 - 2.5e-25 89.9 1.8 6.9e-25 88.4 1.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 TatD_DNase PF01026.21 GAM26533.1 - 1.1e-60 205.2 0.0 1.3e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase ERG2_Sigma1R PF04622.12 GAM26534.1 - 2.5e-59 200.1 0.0 3.2e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Amastin PF07344.11 GAM26534.1 - 0.072 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Amastin surface glycoprotein FNIP PF05725.12 GAM26535.1 - 9.7e-101 329.8 34.5 1.5e-15 57.0 2.1 11.9 13 0 0 13 13 13 10 FNIP Repeat ACDC PF14733.6 GAM26535.1 - 0.051 13.9 0.4 15 6.0 0.0 3.9 4 0 0 4 4 4 0 AP2-coincident C-terminal Pkinase_Tyr PF07714.17 GAM26536.1 - 1.3e-59 201.6 0.0 1.8e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM26536.1 - 8.3e-46 156.5 0.0 1.2e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.22 GAM26536.1 - 9.4e-18 64.2 22.2 1.2e-08 35.1 6.4 2.6 2 0 0 2 2 2 2 LIM domain Pkinase_fungal PF17667.1 GAM26536.1 - 7e-05 21.8 0.2 0.00017 20.5 0.2 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAM26536.1 - 0.0017 18.4 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM26536.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAM26536.1 - 0.012 15.2 0.4 0.038 13.6 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 GAM26536.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 GAM26536.1 - 0.026 13.5 0.0 0.065 12.2 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain DUF2318 PF10080.9 GAM26536.1 - 8.8 6.5 13.0 2.3 8.4 3.0 2.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2318) WD40 PF00400.32 GAM26537.1 - 4.2e-30 103.3 9.9 3.1e-09 37.3 0.3 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM26537.1 - 2.6e-07 30.8 0.0 0.86 9.9 0.0 5.0 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM26537.1 - 0.0087 15.4 0.0 4.8 6.4 0.0 3.1 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 GAM26537.1 - 0.025 13.5 0.1 0.66 8.9 0.0 3.0 3 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TK PF00265.18 GAM26538.1 - 7.5e-64 214.8 0.0 8.5e-64 214.7 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 GAM26538.1 - 0.0066 16.5 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAM26538.1 - 0.12 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea GGDEF PF00990.21 GAM26539.1 - 1.4e-33 115.9 0.0 2.6e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain RasGAP PF00616.19 GAM26540.1 - 1.2e-09 38.2 1.7 8.2e-05 22.4 0.0 3.6 3 0 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase LRR_6 PF13516.6 GAM26540.1 - 8.9e-09 34.7 19.9 0.016 15.2 0.1 8.8 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 GAM26540.1 - 0.00028 21.2 19.3 1.7 9.1 0.2 6.6 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM26540.1 - 0.0023 18.3 10.8 8 7.4 0.2 7.7 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 GAM26540.1 - 0.49 10.2 22.2 1.7 8.5 5.7 6.2 4 3 1 5 5 5 0 Leucine rich repeat Dickkopf_N PF04706.12 GAM26541.1 - 0.03 14.8 13.5 0.03 14.8 13.5 5.5 4 2 1 5 5 5 0 Dickkopf N-terminal cysteine-rich region EB PF01683.18 GAM26541.1 - 0.03 14.6 3.9 0.03 14.6 3.9 7.2 3 2 4 7 7 7 0 EB module DUF5455 PF17537.2 GAM26544.1 - 0.016 15.6 0.5 0.024 15.0 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5455) F-box PF00646.33 GAM26544.1 - 0.86 9.6 3.4 0.33 10.9 0.5 1.8 2 0 0 2 2 2 0 F-box domain DUF5455 PF17537.2 GAM26546.1 - 0.15 12.5 1.1 0.27 11.7 1.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5455) DUF5455 PF17537.2 GAM26548.1 - 0.049 14.0 0.7 0.094 13.1 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5455) Astro_capsid_p PF12226.8 GAM26548.1 - 0.12 11.5 8.7 0.2 10.8 8.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4820 PF16091.5 GAM26548.1 - 0.16 11.3 0.4 0.29 10.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RPA43_OB PF17875.1 GAM26548.1 - 0.31 11.7 1.5 0.59 10.8 1.5 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I F-box PF00646.33 GAM26548.1 - 0.37 10.7 3.2 0.28 11.1 0.3 2.2 2 0 0 2 2 2 0 F-box domain RXT2_N PF08595.11 GAM26548.1 - 0.4 10.7 7.3 0.94 9.5 7.3 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 GAM26548.1 - 0.5 10.0 3.5 0.94 9.1 3.5 1.4 1 0 0 1 1 1 0 FAM176 family MTBP_N PF14918.6 GAM26548.1 - 2.2 7.7 5.5 9.2 5.7 0.3 2.2 2 0 0 2 2 2 0 MDM2-binding Nop14 PF04147.12 GAM26548.1 - 3 6.0 10.4 4.3 5.4 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 GAM26548.1 - 4.6 5.2 16.5 8.1 4.4 16.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 GAM26548.1 - 6.6 5.8 19.4 10 5.1 19.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 GAM26548.1 - 7.7 5.7 18.5 14 4.9 18.5 1.4 1 0 0 1 1 1 0 NOA36 protein YceD PF02620.17 GAM26548.1 - 8.2 6.6 10.2 16 5.7 10.2 1.4 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD CesT PF05932.13 GAM26550.1 - 0.028 14.6 1.6 0.43 10.7 0.0 3.3 4 0 0 4 4 4 0 Tir chaperone protein (CesT) family Rad51 PF08423.11 GAM26551.1 - 2.1e-47 161.5 0.0 4.6e-47 160.4 0.0 1.5 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GAM26551.1 - 6.1e-10 39.0 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 GAM26551.1 - 1.2e-06 28.0 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 GAM26551.1 - 1.5e-06 27.7 0.2 5e-06 26.0 0.2 1.8 1 1 0 1 1 1 1 KaiC RecA PF00154.21 GAM26551.1 - 3e-06 26.9 1.1 0.00018 21.1 0.0 2.2 1 1 0 2 2 2 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 GAM26551.1 - 0.0002 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM26551.1 - 0.031 14.8 0.3 0.096 13.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAM26551.1 - 0.041 14.0 0.0 0.093 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAM26551.1 - 0.1 13.0 0.1 0.3 11.5 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PITH PF06201.13 GAM26552.1 - 5.9e-38 130.5 0.1 7.7e-38 130.1 0.1 1.2 1 0 0 1 1 1 1 PITH domain Tubulin PF00091.25 GAM26553.1 - 1.7e-67 227.5 0.0 2.8e-67 226.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAM26553.1 - 1.5e-46 157.7 0.1 2.5e-46 156.9 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAM26553.1 - 0.00066 19.4 0.0 0.0044 16.7 0.0 2.2 2 0 0 2 2 2 1 Tubulin domain Tubulin PF00091.25 GAM26554.1 - 6.2e-68 228.9 0.0 9.3e-68 228.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAM26554.1 - 2.1e-46 157.2 0.1 3.8e-46 156.4 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAM26554.1 - 0.00017 21.3 0.0 0.00038 20.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 GAM26554.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin like RRM_1 PF00076.22 GAM26555.1 - 9.8e-20 70.2 0.0 1.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RWD PF05773.22 GAM26556.1 - 4.4e-18 65.7 0.0 1e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 RWD domain IBR PF01485.21 GAM26556.1 - 2.7e-12 46.7 56.6 4e-06 27.0 7.4 5.1 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 GAM26556.1 - 0.0082 16.2 7.9 0.0082 16.2 7.9 3.9 5 0 0 5 5 5 1 RING-type zinc-finger Dicty_REP PF05086.12 GAM26556.1 - 0.021 12.8 0.0 0.027 12.5 0.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 GAM26556.1 - 0.053 11.7 8.4 0.08 11.1 8.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RasGAP PF00616.19 GAM26558.1 - 3.5e-31 108.5 0.0 1.4e-30 106.6 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 GAM26558.1 - 1.7e-16 60.6 2.6 3.6e-16 59.6 2.6 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GAM26558.1 - 2.2e-13 50.3 2.2 4.7e-13 49.2 2.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Myosin_TH1 PF06017.13 GAM26558.1 - 3.5e-06 26.8 3.3 0.027 14.2 0.8 2.4 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding CDK2AP PF09806.9 GAM26558.1 - 0.36 10.9 9.6 0.21 11.6 1.1 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ras PF00071.22 GAM26559.1 - 4.4e-32 110.9 0.0 5.2e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM26559.1 - 1.3e-21 77.1 0.0 1.6e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM26559.1 - 2e-13 50.1 0.0 2.4e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 GAM26559.1 - 0.00028 20.7 0.6 0.33 10.6 0.1 2.1 1 1 1 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 GAM26559.1 - 0.0011 19.1 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 GAM26559.1 - 0.0051 16.3 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 GAM26559.1 - 0.017 14.5 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAM26559.1 - 0.04 13.5 0.0 0.078 12.5 0.0 1.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain CAP PF00188.26 GAM26560.1 - 2.8e-11 44.3 0.1 3.7e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PRA1 PF03208.19 GAM26560.1 - 1.2 8.8 5.7 1.9 8.1 5.7 1.3 1 0 0 1 1 1 0 PRA1 family protein Ribosomal_L7Ae PF01248.26 GAM26561.1 - 2.3e-21 75.3 0.3 4.7e-21 74.3 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ParA PF10609.9 GAM26562.1 - 5.9e-90 301.0 0.1 1.2e-89 300.0 0.1 1.5 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAM26562.1 - 6e-11 42.5 0.0 1.5e-09 37.9 0.0 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAM26562.1 - 1.6e-09 37.9 0.1 1.4e-08 34.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 GAM26562.1 - 2.7e-07 30.1 0.1 2.5e-06 26.9 0.3 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 GAM26562.1 - 7.3e-05 22.2 0.0 0.0013 18.1 0.0 2.5 3 0 0 3 3 3 1 ATPase MipZ AAA_26 PF13500.6 GAM26562.1 - 7.7e-05 22.6 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAM26562.1 - 0.00049 20.0 1.4 0.0068 16.3 0.2 2.8 3 0 0 3 3 3 1 RsgA GTPase Fer4_NifH PF00142.18 GAM26562.1 - 0.0012 18.4 0.0 0.053 13.0 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 GAM26562.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.6 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 GAM26562.1 - 0.0038 16.2 0.1 0.0059 15.6 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 GAM26562.1 - 0.0088 15.8 0.0 0.85 9.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 GAM26562.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin CBP_BcsQ PF06564.12 GAM26562.1 - 0.026 14.0 0.0 0.091 12.2 0.0 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 GAM26562.1 - 0.048 13.2 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 GAM26562.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_10 PF12846.7 GAM26562.1 - 0.35 9.7 0.8 15 4.3 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Cullin PF00888.22 GAM26563.1 - 4.9e-217 722.4 27.0 7.6e-217 721.8 27.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAM26563.1 - 8.8e-29 99.4 4.8 4e-28 97.2 4.8 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_IclR PF09339.10 GAM26563.1 - 0.18 11.6 0.0 0.67 9.8 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain MutL_C PF08676.11 GAM26564.1 - 4.5e-16 58.9 0.0 1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 GAM26564.1 - 7.2e-08 32.4 0.0 1.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 GAM26564.1 - 2e-07 30.7 0.1 5.5e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 GAM26564.1 - 0.0082 16.6 0.0 0.038 14.5 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3343 PF11823.8 GAM26564.1 - 0.16 11.5 0.0 0.5 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Rieske PF00355.26 GAM26565.1 - 5.4e-13 48.7 0.0 1e-12 47.8 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 GAM26565.1 - 3.4e-09 37.1 0.0 6.2e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Ribosomal_S9 PF00380.19 GAM26566.1 - 8e-31 107.1 0.0 9.6e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Oxidored_molyb PF00174.19 GAM26566.1 - 0.17 11.5 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 Oxidoreductase molybdopterin binding domain Atg14 PF10186.9 GAM26568.1 - 2.5e-25 89.2 16.4 8.6e-25 87.5 16.4 1.7 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 GAM26568.1 - 7.8e-07 28.3 12.3 1.7e-05 23.9 12.2 2.2 1 1 0 1 1 1 1 Vacuolar protein sorting 38 pP_pnuc_1 PF18165.1 GAM26568.1 - 0.0033 17.3 1.8 0.0076 16.1 1.8 1.7 1 0 0 1 1 1 1 Predicted pPIWI-associating nuclease Ribosomal_S15 PF00312.22 GAM26568.1 - 0.048 13.9 1.3 0.048 13.9 1.3 2.8 1 1 2 3 3 3 0 Ribosomal protein S15 DZR PF12773.7 GAM26568.1 - 0.073 13.1 0.6 0.13 12.3 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon Glyco_transf_10 PF00852.19 GAM26569.1 - 9.8e-33 113.3 0.3 2.1e-32 112.3 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Laminin_G_3 PF13385.6 GAM26569.1 - 3.7e-11 43.4 0.0 6.8e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Glyco_tran_10_N PF17039.5 GAM26569.1 - 0.01 16.2 0.4 0.14 12.7 0.0 2.8 3 0 0 3 3 3 0 Fucosyltransferase, N-terminal TPR_2 PF07719.17 GAM26570.1 - 7.4e-16 56.9 26.6 0.0086 16.1 1.2 11.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAM26570.1 - 1.6e-13 51.0 9.1 0.045 14.3 0.0 7.5 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM26570.1 - 3.9e-13 49.5 10.4 0.00019 21.6 1.9 7.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM26570.1 - 6.7e-13 47.9 27.9 0.0001 22.0 2.0 9.5 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM26570.1 - 5.6e-12 45.4 3.0 0.14 13.0 0.0 8.2 7 2 2 9 9 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM26570.1 - 5.8e-11 41.6 7.3 0.015 15.3 0.0 9.2 9 1 0 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM26570.1 - 7.5e-10 38.9 11.2 2.8e-05 24.2 0.2 5.7 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAM26570.1 - 1.3e-07 31.3 31.6 0.095 13.0 1.4 11.1 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM26570.1 - 4.2e-07 30.5 5.0 1.5 9.5 0.1 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM26570.1 - 8.8e-07 29.0 0.0 0.34 11.1 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM26570.1 - 2.3e-06 27.6 10.3 1.6 9.3 0.2 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM26570.1 - 0.00011 21.8 18.9 0.11 12.2 0.0 7.5 10 0 0 10 10 9 2 TPR repeat TPR_6 PF13174.6 GAM26570.1 - 0.00088 19.8 18.6 3.8 8.4 1.1 9.2 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 GAM26570.1 - 0.001 19.3 1.0 28 5.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 GAM26570.1 - 0.045 13.4 0.0 11 5.7 0.0 2.9 3 0 0 3 3 2 0 Bacterial type III secretion protein (HrpB1_HrpK) NIT PF08376.10 GAM26570.1 - 0.072 13.5 0.4 0.19 12.2 0.4 1.7 1 0 0 1 1 1 0 Nitrate and nitrite sensing COX5A PF02284.16 GAM26570.1 - 0.17 11.9 1.1 0.79 9.8 0.1 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va OGG_N PF07934.12 GAM26570.1 - 0.34 11.0 2.3 1 9.4 0.0 3.1 4 1 0 4 4 3 0 8-oxoguanine DNA glycosylase, N-terminal domain TPR_10 PF13374.6 GAM26570.1 - 1.4 8.9 14.0 4 7.4 0.1 6.6 9 0 0 9 9 9 0 Tetratricopeptide repeat MutS_V PF00488.21 GAM26571.1 - 1.6e-83 279.4 0.4 3.9e-83 278.1 0.4 1.7 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 GAM26571.1 - 2.7e-39 133.9 0.1 8.4e-39 132.3 0.1 1.9 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 GAM26571.1 - 1e-33 117.2 2.7 2.7e-33 115.8 2.7 1.8 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 GAM26571.1 - 5e-21 74.9 1.1 1.2e-20 73.6 1.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 GAM26571.1 - 2.7e-14 53.6 0.0 8e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 GAM26571.1 - 0.12 11.9 0.0 0.43 10.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain RRM_2 PF04059.12 GAM26572.1 - 3.8e-32 110.3 0.5 1.4e-31 108.6 0.6 1.9 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.22 GAM26572.1 - 3.5e-31 106.8 0.1 2.7e-13 49.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM26572.1 - 7.1e-08 32.2 0.0 0.00013 21.7 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 GAM26572.1 - 6.4e-06 25.8 0.1 0.084 12.5 0.0 2.7 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 GAM26572.1 - 0.0008 19.5 0.0 0.0008 19.5 0.0 2.6 2 1 0 2 2 2 1 Smg-4/UPF3 family BRAP2 PF07576.12 GAM26572.1 - 0.021 15.0 0.0 0.021 15.0 0.0 3.0 3 0 0 3 3 3 0 BRCA1-associated protein 2 SAYSvFN PF10260.9 GAM26572.1 - 0.16 12.0 1.2 0.33 10.9 1.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) DUF2730 PF10805.8 GAM26572.1 - 0.8 9.8 2.6 3.3 7.8 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) CLZ PF16526.5 GAM26572.1 - 1.3 9.4 4.0 2.2 8.7 2.6 2.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Aconitase PF00330.20 GAM26572.1 - 3.7 6.4 10.2 6 5.8 10.2 1.2 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) AAA_12 PF13087.6 GAM26573.1 - 3.3e-59 199.9 0.0 8.3e-59 198.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM26573.1 - 2.8e-42 145.3 13.0 2.5e-21 76.6 0.6 3.2 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 GAM26573.1 - 1.6e-12 48.0 0.0 4.5e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM26573.1 - 5.7e-09 36.0 0.0 1.3e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 GAM26573.1 - 6.4e-08 32.5 2.6 4.8e-05 23.0 0.0 3.2 2 1 0 3 3 3 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 GAM26573.1 - 4.6e-06 26.5 0.1 0.33 10.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GAM26573.1 - 0.00042 20.6 0.1 0.023 15.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 GAM26573.1 - 0.00069 19.5 0.0 0.0046 16.8 0.0 2.4 2 1 0 2 2 2 1 Helicase AAA PF00004.29 GAM26573.1 - 0.0034 17.8 0.2 0.021 15.3 0.1 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAM26573.1 - 0.004 16.8 0.1 0.0093 15.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 GAM26573.1 - 0.0079 15.5 0.0 0.0079 15.5 0.0 2.6 3 1 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 GAM26573.1 - 0.011 15.2 0.0 0.049 13.1 0.0 2.1 2 1 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 GAM26573.1 - 0.012 16.1 0.1 0.096 13.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 GAM26573.1 - 0.014 15.5 0.1 0.12 12.3 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 GAM26573.1 - 0.019 14.0 0.0 0.049 12.7 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 GAM26573.1 - 0.05 13.4 0.3 0.12 12.1 0.3 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_5 PF07728.14 GAM26573.1 - 0.086 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 GAM26573.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 GAM26573.1 - 0.12 12.7 0.9 0.27 11.6 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain AAA_7 PF12775.7 GAM26573.1 - 0.13 11.8 0.1 0.84 9.1 0.1 2.3 1 1 1 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 GAM26573.1 - 0.14 12.4 0.2 0.39 10.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAM26573.1 - 0.16 11.4 0.0 0.41 10.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SR-25 PF10500.9 GAM26573.1 - 0.49 10.0 11.2 0.9 9.1 11.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CIA30 PF08547.12 GAM26574.1 - 1.8e-32 112.6 0.0 2.1e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 GAM26574.1 - 0.017 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) RRM_1 PF00076.22 GAM26575.1 - 2.1e-15 56.3 0.0 3.4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM26575.1 - 4.1e-06 26.8 1.1 1.3e-05 25.2 0.1 2.3 2 1 0 2 2 2 1 RNA recognition motif MFS_1 PF07690.16 GAM26576.1 - 2e-25 89.5 42.7 3.3e-21 75.6 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.6 GAM26576.1 - 0.015 15.6 0.5 0.015 15.6 0.5 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Abhydrolase_1 PF00561.20 GAM26577.1 - 3.4e-14 53.1 0.4 3.6e-13 49.8 0.2 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM26577.1 - 3.4e-12 46.2 0.0 4.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAM26577.1 - 6.5e-05 23.6 0.0 8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 GAM26577.1 - 0.021 14.8 0.0 0.046 13.7 0.0 1.6 1 1 0 1 1 1 0 Cutinase ANAPC4_WD40 PF12894.7 GAM26578.1 - 2.5e-13 50.1 1.2 0.2 12.0 0.0 6.5 5 1 0 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain ANAPC3 PF12895.7 GAM26578.1 - 0.022 15.0 4.5 0.93 9.8 0.8 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Y_phosphatase3 PF13350.6 GAM26579.1 - 1.3e-41 143.1 0.0 1.4e-27 97.2 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 GAM26579.1 - 3.8e-05 23.3 0.0 0.00047 19.8 0.0 2.6 2 1 1 3 3 3 1 Tyrosine phosphatase family Abi_C PF14355.6 GAM26579.1 - 0.0079 16.3 0.1 0.026 14.6 0.1 1.8 1 0 0 1 1 1 1 Abortive infection C-terminus a_DG1_N2 PF18424.1 GAM26579.1 - 0.052 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Alpha-Dystroglycan N-terminal domain 2 FSA_C PF10479.9 GAM26579.1 - 1.9 6.5 8.5 2.7 6.0 8.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pkinase_Tyr PF07714.17 GAM26581.1 - 1.9e-50 171.6 0.0 2.5e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM26581.1 - 5.8e-44 150.4 0.0 7.5e-42 143.5 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAM26581.1 - 0.0035 17.3 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM26581.1 - 0.047 12.6 0.0 0.047 12.6 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 GAM26581.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3742 PF12553.8 GAM26584.1 - 4.6 7.4 6.5 4.8 7.3 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Pro-kuma_activ PF09286.11 GAM26585.1 - 3.1e-26 92.4 0.2 3.6e-26 92.2 0.2 1.0 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain ssDNA-exonuc_C PF10141.9 GAM26585.1 - 0.013 15.2 0.3 0.017 14.8 0.3 1.2 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain HTH_54 PF18607.1 GAM26585.1 - 0.021 14.9 0.5 0.037 14.1 0.5 1.3 1 0 0 1 1 1 0 ParA helix turn helix domain HIT PF01230.23 GAM26585.1 - 0.021 15.5 0.3 0.038 14.7 0.3 1.3 1 0 0 1 1 1 0 HIT domain MIT_C PF16565.5 GAM26586.1 - 5.2e-53 178.8 0.1 6e-53 178.6 0.1 1.0 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT Syntaxin-6_N PF09177.11 GAM26586.1 - 0.088 13.4 0.1 0.13 12.8 0.1 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DDE_Tnp_4 PF13359.6 GAM26587.1 - 2.3e-23 82.6 0.4 1.2e-21 77.1 0.3 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM26587.1 - 2.7e-08 33.7 1.9 4.7e-08 32.9 1.9 1.4 1 1 0 1 1 1 1 Transposase DDE domain Med22 PF06179.12 GAM26589.1 - 5.5e-21 74.8 11.1 7.5e-21 74.3 11.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Herpes_pp85 PF04637.12 GAM26589.1 - 0.024 13.1 4.9 0.027 12.9 4.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CDK2AP PF09806.9 GAM26589.1 - 1.6 8.7 10.1 0.096 12.7 1.5 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.9 GAM26589.1 - 6 6.4 15.0 9.7 5.7 15.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CLU PF13236.6 GAM26590.1 - 7.1e-61 205.8 0.0 1.3e-60 205.0 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria LRR_6 PF13516.6 GAM26590.1 - 9e-12 44.1 27.7 0.042 13.9 0.1 11.9 12 0 0 12 12 12 4 Leucine Rich repeat eIF3_p135 PF12807.7 GAM26590.1 - 6.6e-06 26.3 0.1 6.6e-06 26.3 0.1 2.5 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CBFD_NFYB_HMF PF00808.23 GAM26591.1 - 7.2e-16 58.2 0.1 1.5e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM26591.1 - 9.9e-08 32.4 1.7 1.2e-07 32.1 1.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 YL1 PF05764.13 GAM26591.1 - 0.00026 21.2 23.3 0.00033 20.9 23.3 1.1 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 GAM26591.1 - 0.006 16.1 21.5 0.0062 16.0 21.5 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GAM26591.1 - 0.006 14.9 18.7 0.0055 15.0 18.7 1.1 1 0 0 1 1 1 1 Nop14-like family Merozoite_SPAM PF07133.11 GAM26591.1 - 0.0096 15.9 22.8 0.011 15.8 22.8 1.2 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) CDC45 PF02724.14 GAM26591.1 - 0.049 11.9 16.9 0.05 11.9 16.9 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.12 GAM26591.1 - 0.6 8.3 13.2 0.61 8.3 13.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 GAM26591.1 - 0.76 7.8 32.0 1.1 7.3 32.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi RNA_polI_A34 PF08208.11 GAM26591.1 - 0.97 9.5 14.1 1.1 9.3 14.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Sporozoite_P67 PF05642.11 GAM26591.1 - 1.3 7.0 14.2 1.9 6.5 14.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF913 PF06025.12 GAM26591.1 - 1.5 7.7 6.0 1.6 7.6 6.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) UPF0515 PF15135.6 GAM26591.1 - 2 7.7 4.2 2.4 7.5 4.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 SAPS PF04499.15 GAM26591.1 - 9.6 4.9 11.2 10 4.8 11.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Phage_CII PF05269.11 GAM26592.1 - 0.062 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CII protein Vault PF01505.18 GAM26593.1 - 1.6e-47 159.4 0.3 9e-13 48.2 0.0 4.6 4 0 0 4 4 4 4 Major Vault Protein repeat domain Vault_2 PF17794.1 GAM26593.1 - 9.2e-30 102.8 0.2 3e-23 81.9 0.1 2.6 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 GAM26593.1 - 8.6e-05 22.5 0.1 0.068 13.2 0.0 2.8 2 1 0 2 2 2 2 Major Vault Protein Repeat domain CUE PF02845.16 GAM26594.1 - 9.3e-10 38.0 0.6 9.8e-07 28.4 0.1 3.8 3 1 0 3 3 3 2 CUE domain HBS1_N PF08938.10 GAM26594.1 - 0.0011 19.2 0.3 0.0011 19.2 0.3 5.3 2 1 3 5 5 5 1 HBS1 N-terminus DUF3484 PF11983.8 GAM26594.1 - 0.086 14.0 0.5 0.086 14.0 0.5 5.9 4 2 0 4 4 4 0 Membrane-attachment and polymerisation-promoting switch COesterase PF00135.28 GAM26595.1 - 5.9e-122 408.1 0.0 1.3e-121 407.0 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM26595.1 - 1e-07 32.0 0.0 3.2e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM26595.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_3 PF01494.19 GAM26596.1 - 1.7e-06 27.6 0.0 3.8e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Med6 PF04934.14 GAM26597.1 - 1e-41 141.9 0.9 1.5e-41 141.3 0.9 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component AAA_16 PF13191.6 GAM26598.1 - 1.9e-07 31.6 0.1 8.3e-07 29.5 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 GAM26598.1 - 0.00086 19.3 0.0 0.0026 17.7 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 GAM26598.1 - 0.044 14.1 0.0 0.57 10.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain SHOCT PF09851.9 GAM26598.1 - 0.054 13.2 2.0 0.12 12.2 2.0 1.6 1 0 0 1 1 1 0 Short C-terminal domain AAA_19 PF13245.6 GAM26598.1 - 0.055 13.8 0.1 0.68 10.3 0.1 2.3 1 1 0 1 1 1 0 AAA domain OGG_N PF07934.12 GAM26598.1 - 0.084 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain AAA_24 PF13479.6 GAM26598.1 - 0.16 11.7 0.5 2.7 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Ank_4 PF13637.6 GAM26601.1 - 2.2e-17 63.2 0.0 2e-09 37.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM26601.1 - 8.2e-12 45.6 0.0 1.1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM26601.1 - 1.3e-11 44.5 0.0 1.6e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM26601.1 - 6.4e-09 35.9 0.0 1.6e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 GAM26601.1 - 1.9e-07 30.8 0.0 2.2e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Myotub-related PF06602.14 GAM26603.1 - 7.3e-131 436.3 1.4 7.3e-131 436.3 1.4 2.3 3 0 0 3 3 3 1 Myotubularin-like phosphatase domain FERM_f0 PF16511.5 GAM26603.1 - 1.5e-11 44.4 0.8 0.058 13.7 0.0 6.1 5 1 0 5 5 5 3 N-terminal or F0 domain of Talin-head FERM GRAM PF02893.20 GAM26603.1 - 9.4e-05 22.3 0.0 0.00034 20.5 0.0 1.9 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 GAM26603.1 - 0.00049 19.7 1.3 0.039 13.5 0.0 2.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 GAM26603.1 - 0.0067 16.2 0.0 0.023 14.5 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Vps36_ESCRT-II PF11605.8 GAM26603.1 - 0.012 15.8 0.0 0.06 13.5 0.0 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 DUF4724 PF15852.5 GAM26603.1 - 0.013 15.9 0.3 0.071 13.6 0.3 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4724) Y_phosphatase3 PF13350.6 GAM26603.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PI3K_rbd PF00794.18 GAM26603.1 - 0.035 14.3 0.1 0.63 10.2 0.1 2.7 2 1 0 2 2 2 0 PI3-kinase family, ras-binding domain ubiquitin PF00240.23 GAM26603.1 - 0.2 11.4 2.3 11 5.9 0.0 3.8 4 0 0 4 4 4 0 Ubiquitin family BTB PF00651.31 GAM26604.1 - 7.2e-20 71.3 0.9 8.4e-18 64.6 0.0 3.4 3 1 1 4 4 4 1 BTB/POZ domain SUIM_assoc PF16619.5 GAM26604.1 - 0.00087 19.3 0.8 0.00087 19.3 0.8 5.7 6 0 0 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 Ago_N_1 PF18351.1 GAM26604.1 - 0.035 14.5 1.0 0.16 12.4 0.1 2.6 2 0 0 2 2 2 0 Fungal Argonaute N-terminal domain B277 PF17623.2 GAM26604.1 - 1.2 8.1 2.7 2.1 7.3 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function ubiquitin PF00240.23 GAM26605.1 - 9e-13 47.8 0.0 2.3e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 GAM26605.1 - 2e-06 28.3 0.9 6e-06 26.8 0.9 1.9 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.6 GAM26605.1 - 5.8e-06 26.5 1.4 6.8e-06 26.3 0.4 1.8 2 1 0 2 2 2 1 DUF2407 C-terminal domain Rad60-SLD_2 PF13881.6 GAM26605.1 - 9.6e-05 22.5 0.1 0.00032 20.8 0.0 1.9 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 GAM26605.1 - 0.00025 20.8 0.1 0.00052 19.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Plexin_cytopl PF08337.12 GAM26605.1 - 0.037 12.7 1.3 0.056 12.1 1.4 1.4 1 1 0 1 1 1 0 Plexin cytoplasmic RasGAP domain CBFD_NFYB_HMF PF00808.23 GAM26606.1 - 7.9e-28 96.5 1.2 1.3e-27 95.9 1.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM26606.1 - 0.00022 21.6 0.0 0.00022 21.6 0.0 2.4 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAM26606.1 - 0.00026 21.1 0.0 0.00054 20.1 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 GAM26606.1 - 0.0051 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 GAM26606.1 - 0.025 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated TraG_N PF07916.11 GAM26606.1 - 1.9 7.3 5.7 22 3.8 5.7 1.9 1 1 0 1 1 1 0 TraG-like protein, N-terminal region LRR_4 PF12799.7 GAM26607.1 - 0.013 16.0 1.4 0.013 16.0 1.4 5.6 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM26607.1 - 0.23 11.3 17.5 0.09 12.6 1.7 5.6 4 2 1 5 5 5 0 Leucine rich repeat KxDL PF10241.9 GAM26609.1 - 6.7e-24 84.0 5.5 6.7e-24 84.0 5.5 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein DUF4805 PF16063.5 GAM26609.1 - 0.011 15.1 4.4 0.016 14.6 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Roughex PF06020.11 GAM26609.1 - 0.16 11.1 9.8 0.19 10.8 9.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Organ_specific PF10950.8 GAM26609.1 - 4.3 8.1 11.0 0.19 12.4 3.0 2.1 1 1 1 2 2 2 0 Organ specific protein JmjC PF02373.22 GAM26611.1 - 9.9e-17 61.4 0.1 7.1e-16 58.7 0.0 2.6 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 GAM26611.1 - 1.2e-15 58.0 1.0 2.4e-15 56.9 0.2 1.9 2 0 0 2 2 2 1 Cupin-like domain APH PF01636.23 GAM26611.1 - 0.00069 19.6 0.0 0.93 9.4 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family F-box PF00646.33 GAM26611.1 - 0.0011 18.8 0.4 0.0033 17.3 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAM26611.1 - 0.0021 17.9 0.1 0.019 14.9 0.1 2.4 2 0 0 2 2 2 1 F-box-like DUF3891 PF13030.6 GAM26611.1 - 0.036 13.9 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) AbiH PF14253.6 GAM26611.1 - 0.16 11.8 6.0 3.8 7.3 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage abortive infection AbiH Trep_Strep PF09605.10 GAM26612.1 - 0.0023 17.9 0.3 0.0023 17.9 0.3 1.5 2 0 0 2 2 2 1 Hypothetical bacterial integral membrane protein (Trep_Strep) OppC_N PF12911.7 GAM26612.1 - 0.11 12.4 0.4 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C UPF0154 PF03672.13 GAM26612.1 - 0.15 12.1 0.2 0.36 10.9 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) zf-CCCH_2 PF14608.6 GAM26613.1 - 4.3e-25 87.3 77.7 0.00011 22.5 4.4 7.3 7 0 0 7 7 7 7 RNA-binding, Nab2-type zinc finger PWI PF01480.17 GAM26613.1 - 2.1e-07 31.2 0.1 3.9e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 PWI domain Nab2p_Zf1 PF18260.1 GAM26613.1 - 0.011 15.6 1.4 0.011 15.6 1.4 4.0 5 0 0 5 5 5 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf_CCCH_4 PF18345.1 GAM26613.1 - 0.028 14.5 0.3 0.028 14.5 0.3 10.6 10 2 2 12 12 12 0 Zinc finger domain zf-CCCH PF00642.24 GAM26613.1 - 0.036 14.0 0.3 0.036 14.0 0.3 10.2 7 3 2 9 9 9 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAM26613.1 - 0.074 12.9 0.4 0.074 12.9 0.4 8.5 7 2 1 8 8 8 0 CCCH-type zinc finger NADH-u_ox-rdase PF10785.9 GAM26614.1 - 3.1e-15 56.6 1.0 4e-15 56.2 1.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Adaptin_binding PF10199.9 GAM26615.1 - 1.7e-12 48.0 9.3 1.1e-11 45.4 9.3 2.3 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 CS PF04969.16 GAM26616.1 - 3.3e-05 24.8 0.1 5.4e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 CS domain Astro_capsid_p PF12226.8 GAM26616.1 - 1.1 8.3 3.9 1.8 7.6 3.9 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Asp-B-Hydro_N PF05279.11 GAM26617.1 - 0.2 11.7 4.8 0.22 11.5 4.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2981 PF11200.8 GAM26617.1 - 0.56 9.9 10.8 0.61 9.8 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Hid1 PF12722.7 GAM26617.1 - 3.8 5.5 16.2 4 5.4 16.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 GAM26617.1 - 4.5 6.2 14.6 4.9 6.1 14.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 GAM26617.1 - 4.8 4.2 18.2 4.7 4.2 18.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF966 PF06136.13 GAM26617.1 - 7 6.3 19.3 7.9 6.1 19.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Kinesin PF00225.23 GAM26619.1 - 1.4e-94 316.8 3.5 1.4e-94 316.8 3.5 2.3 2 1 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 GAM26619.1 - 1.1e-18 67.6 0.2 1.1e-18 67.6 0.2 2.3 2 1 0 2 2 2 1 Microtubule binding Phytochelatin PF05023.14 GAM26619.1 - 0.067 12.4 0.8 0.17 11.1 0.8 1.6 1 0 0 1 1 1 0 Phytochelatin synthase SAM_1 PF00536.30 GAM26620.1 - 1.2e-06 28.9 0.4 2.6e-06 27.8 0.2 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM26620.1 - 8.2e-05 22.6 0.8 0.00023 21.2 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Reductase_C PF14759.6 GAM26620.1 - 0.062 13.9 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 Reductase C-terminal Ribosomal_60s PF00428.19 GAM26620.1 - 0.26 11.9 0.2 0.26 11.9 0.2 2.0 2 1 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_C1 PF00112.23 GAM26621.1 - 7.8e-51 173.2 5.1 1.3e-50 172.5 5.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 GAM26621.1 - 7.7e-14 52.6 3.1 7.7e-14 52.6 3.1 2.5 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Peptidase_C1_2 PF03051.15 GAM26621.1 - 0.0047 15.8 0.2 0.059 12.1 0.2 2.0 2 0 0 2 2 2 1 Peptidase C1-like family Nup35_RRM_2 PF14605.6 GAM26621.1 - 0.0054 16.7 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif SOG2 PF10428.9 GAM26621.1 - 0.021 14.0 2.5 0.03 13.6 2.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF908 PF06012.12 GAM26621.1 - 0.23 10.8 5.6 0.37 10.2 5.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4106 PF13388.6 GAM26621.1 - 0.57 9.4 27.4 1.9 7.6 27.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4106) Mucin PF01456.17 GAM26621.1 - 0.59 10.1 25.2 1.2 9.1 25.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 GAM26621.1 - 0.66 10.4 6.4 1.8 9.0 6.4 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Nucleo_P87 PF07267.11 GAM26621.1 - 4.3 6.1 17.7 6.6 5.5 17.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ndc1_Nup PF09531.10 GAM26621.1 - 6.8 5.2 6.5 9.5 4.8 6.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Inhibitor_I29 PF08246.12 GAM26622.1 - 3.3e-14 53.0 0.1 7.4e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Podoplanin PF05808.11 GAM26622.1 - 0.0024 18.0 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 Podoplanin DUF3042 PF11240.8 GAM26622.1 - 1.5 8.9 4.8 0.63 10.1 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) VSP PF03302.13 GAM26622.1 - 3.4 6.4 4.9 4.6 6.0 4.9 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Glyco_hydro_47 PF01532.20 GAM26623.1 - 2.3e-115 386.1 1.8 2.7e-115 385.9 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 GAM26623.1 - 0.038 13.2 0.0 5.6 6.1 0.0 2.4 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glycos_transf_2 PF00535.26 GAM26624.1 - 2.1e-17 63.5 0.1 4.2e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAM26624.1 - 1.9e-05 24.7 0.1 7.5e-05 22.7 0.1 1.8 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GAM26624.1 - 3.2e-05 23.5 0.0 6.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAM26624.1 - 0.0012 18.7 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF373 PF04123.13 GAM26624.1 - 0.093 12.2 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4573 PF15140.6 GAM26625.1 - 0.011 15.6 27.2 0.015 15.1 11.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4573) GCIP PF13324.6 GAM26625.1 - 0.26 10.8 6.8 0.052 13.1 3.7 1.4 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting BUD22 PF09073.10 GAM26625.1 - 0.37 10.1 10.9 0.49 9.7 10.9 1.1 1 0 0 1 1 1 0 BUD22 WRNPLPNID PF15017.6 GAM26625.1 - 8.7 7.3 9.7 0.28 12.1 3.2 1.8 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Nop14 PF04147.12 GAM26625.1 - 9.4 4.3 9.9 14 3.8 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family FNIP PF05725.12 GAM26626.1 - 2e-38 130.3 24.0 9.3e-09 35.3 0.0 8.0 6 2 0 7 7 7 7 FNIP Repeat Amino_oxidase PF01593.24 GAM26627.1 - 1.2e-38 133.6 0.1 1.2e-37 130.3 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM26627.1 - 2.1e-08 34.2 0.0 5.3e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAM26627.1 - 0.031 13.5 0.4 0.049 12.9 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 GAM26627.1 - 0.047 12.9 0.5 0.14 11.4 0.5 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM26627.1 - 0.048 14.2 0.7 0.16 12.6 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM26627.1 - 0.096 11.9 0.1 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAM26627.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAM26627.1 - 0.15 10.7 0.9 0.31 9.7 0.9 1.5 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_47 PF01532.20 GAM26628.1 - 1.1e-144 482.7 0.5 1.4e-144 482.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FAM176 PF14851.6 GAM26628.1 - 0.089 12.5 1.2 0.18 11.5 1.2 1.4 1 0 0 1 1 1 0 FAM176 family AAT PF03417.16 GAM26629.1 - 2.8e-11 43.6 0.0 1.9e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase FcoT PF10862.8 GAM26629.1 - 0.0032 17.1 0.1 0.0061 16.2 0.1 1.4 1 0 0 1 1 1 1 FcoT-like thioesterase domain HTH_Tnp_1_2 PF13022.6 GAM26629.1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Mad3_BUB1_I PF08311.12 GAM26631.1 - 2.3e-41 140.7 5.0 5.1e-41 139.5 5.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 GAM26631.1 - 7e-05 22.3 0.1 0.00014 21.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26631.1 - 0.00031 20.1 0.2 0.00098 18.5 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 GAM26631.1 - 0.033 14.3 0.5 0.089 12.9 0.5 1.7 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein JAKMIP_CC3 PF16034.5 GAM26631.1 - 0.065 13.2 1.4 0.17 11.8 1.4 1.8 1 0 0 1 1 1 0 JAKMIP CC3 domain Nucleoporin_FG PF13634.6 GAM26631.1 - 5.3 8.0 29.3 0.26 12.2 13.2 3.5 2 1 1 3 3 3 0 Nucleoporin FG repeat region Ribul_P_3_epim PF00834.19 GAM26632.1 - 2.1e-42 144.8 0.1 2.5e-42 144.5 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family V-SNARE_C PF12352.8 GAM26633.1 - 0.074 13.4 1.5 1.5 9.2 0.5 2.6 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Ribosomal_S13 PF00416.22 GAM26633.1 - 0.12 12.8 0.2 0.12 12.8 0.2 2.3 2 1 1 3 3 3 0 Ribosomal protein S13/S18 Laminin_II PF06009.12 GAM26633.1 - 0.19 11.7 6.9 0.63 10.1 6.9 1.8 1 0 0 1 1 1 0 Laminin Domain II Synaptobrevin PF00957.21 GAM26633.1 - 1.8 8.4 10.3 0.12 12.2 4.3 2.1 2 0 0 2 2 2 0 Synaptobrevin DUF948 PF06103.11 GAM26633.1 - 3.3 8.0 4.8 1.3 9.4 1.6 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MCU PF04678.13 GAM26633.1 - 8.3 6.5 7.9 1.2 9.2 1.8 2.2 2 1 0 2 2 2 0 Mitochondrial calcium uniporter PA26 PF04636.13 GAM26634.1 - 2.5e-74 250.8 0.0 2.9e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) UPF0181 PF03701.14 GAM26634.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) IL22 PF14565.6 GAM26635.1 - 0.077 13.3 0.0 1.5e+02 2.6 0.0 5.1 3 3 4 7 7 7 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Het-C PF07217.11 GAM26635.1 - 1.1 7.7 4.6 9.6 4.6 0.8 2.2 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C DUF3808 PF10300.9 GAM26636.1 - 4.5e-34 118.0 6.9 1e-33 116.8 6.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.6 GAM26636.1 - 4e-05 24.2 0.4 0.022 15.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM26636.1 - 0.00096 19.6 10.1 0.65 10.7 0.6 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM26636.1 - 0.0015 19.2 1.2 3.8 8.6 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM26636.1 - 0.003 18.0 0.9 1.3 9.6 0.3 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM26636.1 - 0.019 15.1 15.4 14 6.1 0.9 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF4995 PF16386.5 GAM26636.1 - 0.021 14.8 0.3 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function BACK PF07707.15 GAM26636.1 - 0.072 13.2 0.2 0.23 11.6 0.2 1.8 1 0 0 1 1 1 0 BTB And C-terminal Kelch Vps16_C PF04840.12 GAM26637.1 - 1.5e-74 250.9 5.1 2.2e-74 250.4 5.1 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 GAM26637.1 - 2.2e-50 171.6 0.4 4.8e-50 170.5 0.4 1.6 1 1 0 1 1 1 1 Vps16, N-terminal region Tautomerase_2 PF14552.6 GAM26637.1 - 0.093 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Tautomerase enzyme Pkinase PF00069.25 GAM26638.1 - 3.2e-62 210.3 0.2 4.2e-62 209.9 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26638.1 - 3.5e-28 98.6 0.0 7.4e-28 97.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM26638.1 - 0.0002 20.8 0.0 0.00076 18.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAM26638.1 - 0.00092 18.3 1.6 0.00092 18.3 1.6 2.0 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 GAM26638.1 - 0.0015 18.5 0.0 0.053 13.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM26638.1 - 0.0053 15.6 1.0 0.15 10.8 0.0 2.7 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 GAM26638.1 - 0.0096 15.3 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GAM26638.1 - 0.011 15.3 1.2 0.038 13.6 0.2 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase FNIP PF05725.12 GAM26639.1 - 1.6e-75 249.0 32.1 2.2e-15 56.5 1.0 8.0 6 1 0 7 7 7 7 FNIP Repeat DUF2203 PF09969.9 GAM26639.1 - 0.1 13.3 0.0 0.17 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) E1_DerP2_DerF2 PF02221.15 GAM26640.1 - 0.042 14.3 0.7 0.26 11.7 0.0 2.5 2 0 0 2 2 2 0 ML domain EGF_2 PF07974.13 GAM26640.1 - 0.078 13.4 13.7 0.15 12.5 13.7 1.5 1 0 0 1 1 1 0 EGF-like domain DUF4351 PF14261.6 GAM26641.1 - 0.17 12.0 0.1 7.6 6.7 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4351) Ank_2 PF12796.7 GAM26643.1 - 2.5e-77 255.5 9.2 9.4e-18 64.6 0.1 6.6 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26643.1 - 3.7e-74 244.2 10.1 5.8e-12 45.9 0.0 11.0 1 1 9 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 GAM26643.1 - 1.6e-64 211.7 18.6 2.9e-06 27.4 0.0 13.3 13 0 0 13 13 13 13 Ankyrin repeat Ank_3 PF13606.6 GAM26643.1 - 3.3e-63 202.1 4.1 0.00042 20.5 0.0 13.3 13 0 0 13 13 13 13 Ankyrin repeat Ank_5 PF13857.6 GAM26643.1 - 5.1e-62 205.1 11.5 1.2e-11 44.6 0.3 8.5 4 2 3 8 8 8 8 Ankyrin repeats (many copies) SOG2 PF10428.9 GAM26643.1 - 6.3 5.9 18.9 9.9 5.2 18.9 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein W2 PF02020.18 GAM26644.1 - 2.3e-20 72.5 7.3 2.3e-20 72.5 7.3 2.7 3 0 0 3 3 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 GAM26644.1 - 1.1e-11 44.9 0.0 5.8e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 GAM26644.1 - 1.5e-08 34.0 25.7 3.2e-05 23.5 7.3 4.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAM26644.1 - 0.00054 19.7 22.6 0.27 11.0 5.5 3.7 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 GAM26644.1 - 0.0026 16.0 4.8 0.029 12.5 5.7 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 GAM26644.1 - 0.003 17.9 0.0 0.0055 17.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 GAM26644.1 - 0.045 12.7 5.9 0.036 13.0 2.4 2.3 2 1 0 2 2 2 0 L-fucokinase DUF2457 PF10446.9 GAM26644.1 - 0.67 9.0 36.1 0.099 11.8 17.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 GAM26644.1 - 1.9 8.4 17.2 0.2 11.5 0.6 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region EBV-NA3 PF05009.12 GAM26644.1 - 6.9 6.1 13.9 6.2 6.3 2.8 2.3 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RXT2_N PF08595.11 GAM26644.1 - 8.7 6.4 16.5 8.4 6.4 3.7 2.8 2 0 0 2 2 2 0 RXT2-like, N-terminal PK PF00224.21 GAM26645.1 - 1.6e-147 490.9 9.8 2.3e-147 490.5 9.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAM26645.1 - 6e-28 97.4 0.4 1.9e-27 95.8 0.1 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAM26645.1 - 0.00055 19.1 1.1 0.00099 18.3 1.1 1.5 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family FNIP PF05725.12 GAM26646.1 - 2.1e-56 187.8 28.3 8.1e-13 48.3 0.3 8.1 5 1 3 8 8 8 8 FNIP Repeat Phage_min_tail PF05939.13 GAM26646.1 - 0.079 13.4 0.0 4.7 7.6 0.0 3.4 3 1 1 4 4 4 0 Phage minor tail protein LRR_5 PF13306.6 GAM26646.1 - 9.4 6.2 9.3 21 5.1 1.8 3.3 1 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) AAA PF00004.29 GAM26647.1 - 3.5e-05 24.2 0.0 0.00078 19.9 0.0 2.5 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM26647.1 - 0.011 16.1 0.0 1.3 9.3 0.0 2.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 GAM26647.1 - 0.021 14.8 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 GAM26647.1 - 0.036 12.9 0.0 1.1 8.0 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain AAA_22 PF13401.6 GAM26647.1 - 0.17 12.2 0.0 0.47 10.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DNA_pol_B_2 PF03175.13 GAM26648.1 - 2.8e-06 26.5 0.8 6.1e-06 25.4 0.8 1.5 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral zf_UBZ PF18439.1 GAM26650.1 - 0.086 12.5 0.2 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger DUF3447 PF11929.8 GAM26651.1 - 0.0012 18.7 0.5 0.92 9.5 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) Ank_2 PF12796.7 GAM26651.1 - 0.011 16.3 0.3 1.9 9.1 0.1 2.9 1 1 1 3 3 3 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM26651.1 - 0.028 14.9 2.4 7 7.6 0.1 3.6 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 GAM26652.1 - 0.00065 20.2 0.6 8.2 7.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26652.1 - 0.015 15.9 2.1 2.5 8.8 0.0 4.0 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26652.1 - 0.39 11.4 3.9 49 5.0 0.0 4.4 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 GAM26653.1 - 3.1e-07 30.9 10.1 0.83 10.3 0.1 7.5 5 3 2 7 7 7 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM26653.1 - 0.008 16.6 12.6 78 4.4 0.1 8.9 9 0 0 9 9 9 0 Ankyrin repeat ACDC PF14733.6 GAM26653.1 - 0.011 16.1 1.4 0.037 14.3 0.1 2.6 2 0 0 2 2 2 0 AP2-coincident C-terminal Ank_4 PF13637.6 GAM26653.1 - 0.13 12.9 6.0 26 5.5 0.0 6.4 6 1 2 8 8 8 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM26653.1 - 0.14 12.5 3.9 19 5.7 0.0 5.3 6 0 0 6 6 6 0 Ankyrin repeats (many copies) DUF3447 PF11929.8 GAM26653.1 - 0.18 11.8 7.9 18 5.4 0.1 5.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) FCD PF07729.12 GAM26653.1 - 1.6 9.2 5.5 3.6 8.0 0.5 3.3 4 0 0 4 4 4 0 FCD domain SKI PF01202.22 GAM26654.1 - 5e-16 59.2 0.0 5.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 GAM26654.1 - 7.7e-09 36.2 0.0 1.5e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAM26654.1 - 4.1e-08 33.5 0.0 5.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 GAM26654.1 - 8.5e-05 22.5 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Cytidylate_kin PF02224.18 GAM26654.1 - 0.00016 21.5 0.2 0.0072 16.1 0.0 2.2 2 1 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 GAM26654.1 - 0.002 18.5 0.0 0.0038 17.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 GAM26654.1 - 0.0055 16.6 0.1 0.68 9.8 0.0 2.3 2 0 0 2 2 2 2 Deoxynucleoside kinase Cytidylate_kin2 PF13189.6 GAM26654.1 - 0.044 13.9 0.0 0.062 13.4 0.0 1.5 1 1 0 1 1 1 0 Cytidylate kinase-like family DUF2075 PF09848.9 GAM26654.1 - 0.13 11.4 0.2 0.42 9.8 0.3 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ploopntkinase1 PF18748.1 GAM26654.1 - 0.15 11.5 0.1 4.3 6.8 0.0 2.5 2 1 1 3 3 3 0 P-loop Nucleotide Kinase1 Glyco_hydro_20 PF00728.22 GAM26655.1 - 1.6e-90 304.1 2.2 1.9e-90 303.8 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAM26655.1 - 2e-14 54.4 1.2 1.1e-13 52.0 1.2 2.1 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAM26655.1 - 7.8e-06 26.7 0.1 1.4e-05 25.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 OppC_N PF12911.7 GAM26655.1 - 0.0023 17.9 1.0 0.0086 16.0 0.0 2.3 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C Glyco_hydro_20 PF00728.22 GAM26656.1 - 1.2e-78 265.1 0.1 1.4e-78 264.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAM26656.1 - 6.5e-14 52.8 0.4 2.4e-12 47.7 0.4 2.4 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAM26656.1 - 9.8e-06 26.4 0.0 1.9e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Pro_CA PF00484.19 GAM26657.1 - 9.2e-52 175.5 0.9 3.6e-51 173.5 0.1 2.0 2 0 0 2 2 2 1 Carbonic anhydrase PH PF00169.29 GAM26659.1 - 3.6e-18 66.0 0.7 6.9e-18 65.1 0.6 1.5 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 GAM26659.1 - 2.2e-07 31.1 0.1 3.8e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAM26659.1 - 7.3e-07 29.6 1.5 6.7e-06 26.5 1.5 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 GAM26659.1 - 6e-06 26.3 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 GAM26659.1 - 0.00066 19.9 0.0 0.0017 18.6 0.0 1.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 GAM26659.1 - 0.012 16.0 0.3 0.1 13.0 0.3 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PH_16 PF17838.1 GAM26659.1 - 0.048 13.5 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 PH domain DUF4003 PF13170.6 GAM26659.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) DEAD PF00270.29 GAM26660.1 - 1.3e-53 181.4 0.0 4.4e-53 179.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM26660.1 - 4.2e-15 56.0 0.1 3.4e-13 49.9 0.1 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM26660.1 - 1.5e-06 28.4 0.0 3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pex19 PF04614.12 GAM26661.1 - 1.3e-08 35.0 32.2 3.5e-08 33.5 14.7 3.1 2 1 0 2 2 2 1 Pex19 protein family Phage_Gp19 PF09355.10 GAM26661.1 - 0.0086 16.5 2.3 0.017 15.5 2.3 1.4 1 0 0 1 1 1 1 Phage protein Gp19/Gp15/Gp42 CAP_N PF01213.19 GAM26661.1 - 0.058 12.9 3.1 0.42 10.0 0.5 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal SGS PF05002.15 GAM26661.1 - 0.06 13.5 7.2 5.1 7.3 0.3 3.7 3 0 0 3 3 3 0 SGS domain CCDC24 PF15669.5 GAM26661.1 - 0.13 12.1 1.0 0.24 11.3 1.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family GET2 PF08690.10 GAM26661.1 - 0.36 10.4 25.4 0.41 10.3 11.4 2.6 1 1 0 2 2 2 0 GET complex subunit GET2 NUDE_C PF04880.13 GAM26661.1 - 0.47 10.9 5.2 0.97 9.9 5.2 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region FAM199X PF15814.5 GAM26661.1 - 0.51 9.3 4.7 0.83 8.7 4.7 1.3 1 0 0 1 1 1 0 Protein family FAM199X Mito_fiss_reg PF05308.11 GAM26661.1 - 0.53 10.3 8.7 0.31 11.1 4.3 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator HNF-1_N PF04814.13 GAM26661.1 - 0.65 10.6 9.4 0.47 11.0 4.1 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Mucin PF01456.17 GAM26661.1 - 3.7 7.5 28.7 6.6 6.7 28.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 GAM26661.1 - 4.8 5.2 13.2 6.7 4.7 13.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MGC-24 PF05283.11 GAM26661.1 - 7.8 6.9 12.4 15 6.0 12.4 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin LRR_6 PF13516.6 GAM26662.1 - 5.7e-05 22.8 17.4 0.027 14.5 0.1 5.7 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.6 GAM26662.1 - 8.6e-05 22.2 10.2 0.008 15.9 0.4 4.5 4 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 GAM26662.1 - 0.0002 21.7 18.5 0.001 19.4 0.4 6.0 4 1 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM26662.1 - 1.5 9.7 17.0 5.8 7.9 0.1 6.2 7 1 0 7 7 7 0 Leucine Rich Repeat Acetyltransf_1 PF00583.25 GAM26664.1 - 5.1e-05 23.5 0.0 8.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM26664.1 - 0.0012 19.3 0.0 0.0025 18.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAM26664.1 - 0.044 13.9 0.0 0.081 13.1 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 GAM26664.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAM26664.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase RhoGAP PF00620.27 GAM26666.1 - 2.6e-32 111.7 0.0 5.9e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Med19 PF10278.9 GAM26666.1 - 0.028 14.4 10.6 0.06 13.3 10.6 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SART-1 PF03343.13 GAM26666.1 - 0.065 11.8 11.5 0.09 11.3 11.5 1.1 1 0 0 1 1 1 0 SART-1 family DUF3464 PF11947.8 GAM26666.1 - 0.086 12.6 0.5 0.19 11.5 0.5 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Peptidase_S49_N PF08496.10 GAM26666.1 - 0.56 10.3 7.7 0.93 9.5 7.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SR-25 PF10500.9 GAM26666.1 - 0.69 9.5 19.3 0.017 14.8 10.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RNA_polI_A34 PF08208.11 GAM26666.1 - 9.3 6.3 20.8 30 4.6 20.8 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ank_4 PF13637.6 GAM26667.1 - 8e-06 26.3 3.2 2.1 9.0 0.0 6.9 6 1 0 6 6 6 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM26667.1 - 1.6e-05 25.4 12.4 3.5 8.3 0.0 7.7 7 3 2 9 9 9 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM26667.1 - 0.00024 21.3 9.1 4.9 8.0 0.3 8.0 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 GAM26667.1 - 0.0038 17.5 4.2 8.1 6.9 0.1 5.7 8 0 0 8 8 8 1 Ankyrin repeats (many copies) O-ag_pol_Wzy PF14296.6 GAM26667.1 - 0.076 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy Ank_2 PF12796.7 GAM26668.1 - 6.7e-09 36.2 6.7 5 7.8 0.0 8.4 6 2 1 7 7 7 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26668.1 - 2.3e-06 28.1 3.5 1.6 9.4 0.1 7.9 7 3 4 11 11 11 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26668.1 - 0.0028 18.0 8.7 58 4.8 0.0 8.5 9 0 0 9 9 9 0 Ankyrin repeat Ank_5 PF13857.6 GAM26668.1 - 0.0052 17.1 7.8 22 5.5 0.0 6.9 9 0 0 9 9 9 2 Ankyrin repeats (many copies) CBM_20 PF00686.19 GAM26669.1 - 2.4e-19 69.0 0.1 3.6e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 Starch binding domain zf-C3HC4_2 PF13923.6 GAM26669.1 - 3.4e-11 42.8 4.7 3.4e-11 42.8 4.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM26669.1 - 3.1e-09 36.5 4.6 3.1e-09 36.5 4.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM26669.1 - 1.8e-08 34.3 7.9 3.9e-08 33.2 7.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAM26669.1 - 2.4e-08 33.8 6.2 6.3e-08 32.5 6.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAM26669.1 - 4.6e-08 32.8 5.2 9.7e-08 31.8 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 GAM26669.1 - 5.2e-08 33.0 0.1 9.9e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 U-box domain zf-RING_2 PF13639.6 GAM26669.1 - 1.1e-07 32.0 5.5 1.1e-07 32.0 5.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-Nse PF11789.8 GAM26669.1 - 6.5e-07 29.1 3.2 1.4e-06 28.0 3.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 GAM26669.1 - 1.7e-06 28.1 5.1 3.8e-06 27.0 5.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAM26669.1 - 8.9e-05 22.7 3.6 8.9e-05 22.7 3.6 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAM26669.1 - 0.00012 21.9 8.4 0.00022 21.0 7.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 GAM26669.1 - 0.00024 20.8 2.0 0.00062 19.5 2.0 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 GAM26669.1 - 0.0088 15.7 3.1 0.0088 15.7 3.1 2.0 2 0 0 2 2 2 1 P-11 zinc finger Sina PF03145.16 GAM26669.1 - 0.083 12.8 1.3 0.14 12.1 1.3 1.4 1 0 0 1 1 1 0 Seven in absentia protein family zf-RING_6 PF14835.6 GAM26669.1 - 0.093 12.6 1.7 0.2 11.6 1.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 GAM26669.1 - 0.41 10.8 9.5 0.073 13.2 3.6 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 Dynamin_N PF00350.23 GAM26670.1 - 1.2e-24 87.2 6.3 4.3e-12 46.4 0.1 3.5 3 1 1 4 4 4 2 Dynamin family MMR_HSR1 PF01926.23 GAM26670.1 - 2.7e-13 50.0 0.4 2.5e-11 43.6 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM26670.1 - 2e-05 24.2 0.1 9.1e-05 22.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAM26670.1 - 4.3e-05 23.1 0.1 0.076 12.5 0.0 2.7 2 0 0 2 2 2 2 Ferrous iron transport protein B Roc PF08477.13 GAM26670.1 - 0.0002 21.6 0.0 0.0011 19.2 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 GAM26670.1 - 0.00046 19.6 1.8 0.0031 16.9 0.7 2.8 2 1 0 2 2 2 1 AIG1 family IIGP PF05049.13 GAM26670.1 - 0.00052 19.2 2.3 0.0084 15.2 0.0 2.9 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 GAM26670.1 - 0.0011 18.9 6.3 0.2 11.6 0.0 3.2 2 1 1 3 3 2 2 RsgA GTPase Ras PF00071.22 GAM26670.1 - 0.0036 16.9 0.0 0.029 14.0 0.0 2.4 1 1 0 1 1 1 1 Ras family Septin PF00735.18 GAM26670.1 - 0.0046 16.3 0.2 0.094 12.0 0.0 2.7 2 0 0 2 2 2 1 Septin ATP_bind_1 PF03029.17 GAM26670.1 - 0.022 14.6 0.1 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 GAM26670.1 - 0.067 12.5 0.5 1.2 8.4 0.0 2.6 2 1 1 3 3 3 0 FtsK/SpoIIIE family Phasin PF05597.11 GAM26670.1 - 0.073 13.1 5.8 0.99 9.4 0.1 3.8 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Nup54 PF13874.6 GAM26670.1 - 4.6 7.3 9.3 1.3 9.1 4.9 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 RabGAP-TBC PF00566.18 GAM26672.1 - 1.8e-56 191.2 0.5 1.8e-56 191.2 0.5 2.9 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 GAM26672.1 - 1.2e-55 186.1 3.6 1.3e-13 51.4 0.0 5.5 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 GAM26672.1 - 7e-48 159.1 13.1 2.6e-06 27.6 0.2 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 GAM26672.1 - 1.5e-47 159.3 6.3 3.6e-11 43.4 0.4 7.1 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26672.1 - 2.2e-38 125.9 4.7 0.00058 20.1 0.1 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 GAM26672.1 - 6.3e-34 115.6 1.9 9.6e-07 29.0 0.0 6.3 2 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM26674.1 - 8.3e-45 150.6 16.0 1.6e-05 25.4 0.1 11.2 7 2 4 11 11 11 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM26674.1 - 1.7e-41 140.7 21.0 1.1e-07 32.4 0.3 7.8 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM26674.1 - 5.5e-37 125.4 25.0 0.00011 22.5 0.0 14.7 3 2 11 15 15 15 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26674.1 - 2.7e-18 64.2 11.7 5.1 8.0 0.0 14.6 15 1 2 17 17 17 3 Ankyrin repeat DUF5049 PF16468.5 GAM26674.1 - 4.1e-11 42.6 6.2 15 5.5 0.0 11.1 9 3 5 14 14 14 3 Domain of unknown function (DUF5049) Ank PF00023.30 GAM26674.1 - 3.2e-06 27.3 6.1 88 3.8 0.0 10.7 8 3 0 8 8 8 0 Ankyrin repeat HTH_22 PF13309.6 GAM26674.1 - 0.065 13.3 0.8 9.3 6.4 0.0 4.7 7 0 0 7 7 7 0 HTH domain 7tm_1 PF00001.21 GAM26675.1 - 7.9e-13 48.3 13.8 7.9e-13 48.3 13.8 2.1 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 GAM26675.1 - 2.1e-12 46.9 17.2 3.2e-12 46.3 17.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 GAM26675.1 - 0.0074 16.3 0.1 0.0074 16.3 0.1 2.8 2 1 1 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Abhydrolase_9_N PF15420.6 GAM26675.1 - 0.074 13.0 2.0 0.22 11.5 2.0 1.7 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus FNIP PF05725.12 GAM26677.1 - 8.5e-70 230.7 27.3 2.1e-12 47.0 1.3 9.9 6 3 3 10 10 10 9 FNIP Repeat LRR_5 PF13306.6 GAM26677.1 - 0.0025 17.8 0.0 1.6 8.7 0.0 3.4 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Pkinase PF00069.25 GAM26678.1 - 4.9e-67 226.1 0.1 9.4e-67 225.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Calpain_III PF01067.22 GAM26678.1 - 4.1e-53 179.4 12.3 1.9e-15 57.3 0.0 5.3 5 1 0 5 5 5 4 Calpain large subunit, domain III Pkinase_Tyr PF07714.17 GAM26678.1 - 5.3e-49 166.8 0.0 8.4e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM26678.1 - 0.00021 20.2 4.7 0.00027 19.8 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM26678.1 - 0.051 12.5 0.0 0.051 12.5 0.0 2.6 3 1 0 3 3 3 0 Haspin like kinase domain Abi_2 PF07751.11 GAM26678.1 - 0.068 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Abi-like protein FAM220 PF15487.6 GAM26678.1 - 8.6 5.9 9.8 16 5.0 9.8 1.5 1 0 0 1 1 1 0 FAM220 family Fe-ADH PF00465.19 GAM26679.1 - 3e-101 338.9 0.0 3.6e-101 338.6 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAM26679.1 - 5.9e-12 45.8 0.9 2.7e-06 27.3 0.0 2.7 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase SRF-TF PF00319.18 GAM26680.1 - 4.9e-20 70.8 0.2 8.1e-20 70.0 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) P34-Arc PF04045.14 GAM26681.1 - 9.3e-81 271.1 0.0 1.1e-80 270.8 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ABC2_membrane PF01061.24 GAM26682.1 - 2.9e-61 206.6 44.8 1.2e-38 132.7 23.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 GAM26682.1 - 5.8e-50 169.4 0.0 3.6e-25 89.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 GAM26682.1 - 8.6e-08 32.3 0.2 0.0036 17.2 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 GAM26682.1 - 4.2e-07 30.1 0.1 0.2 11.4 0.0 3.8 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 GAM26682.1 - 4.2e-06 26.8 0.1 0.071 13.0 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_29 PF13555.6 GAM26682.1 - 5.9e-06 25.9 0.2 0.016 14.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM26682.1 - 6.9e-06 26.5 0.1 0.13 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain PDR_CDR PF06422.12 GAM26682.1 - 8.7e-06 25.6 1.3 8.7e-06 25.6 1.3 3.4 4 0 0 4 4 2 1 CDR ABC transporter PDR_assoc PF08370.11 GAM26682.1 - 9e-06 25.3 4.1 0.0015 18.3 0.0 2.9 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_22 PF13401.6 GAM26682.1 - 1.2e-05 25.7 0.0 0.047 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAM26682.1 - 3.4e-05 24.4 0.4 0.27 11.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 GAM26682.1 - 0.00017 21.5 0.1 0.37 10.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 GAM26682.1 - 0.0002 21.9 1.9 0.62 10.5 0.2 3.0 2 1 1 3 3 3 2 AAA domain AAA_25 PF13481.6 GAM26682.1 - 0.00023 20.8 0.0 0.064 12.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 GAM26682.1 - 0.00024 21.5 0.1 0.3 11.5 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 GAM26682.1 - 0.00035 20.3 0.0 0.71 9.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 GAM26682.1 - 0.0013 18.9 0.1 0.94 9.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAM26682.1 - 0.0017 18.6 0.6 1.8 8.7 0.3 2.4 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 GAM26682.1 - 0.002 17.9 0.8 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 GAM26682.1 - 0.0025 17.9 0.2 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATPase_2 PF01637.18 GAM26682.1 - 0.0038 17.2 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 GAM26682.1 - 0.0043 16.8 0.3 0.88 9.3 0.2 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAM26682.1 - 0.0055 17.1 0.0 4 7.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase CoA_binding_3 PF13727.6 GAM26682.1 - 0.014 15.4 7.2 0.031 14.3 0.6 2.7 2 0 0 2 2 2 0 CoA-binding domain RuvB_N PF05496.12 GAM26682.1 - 0.02 14.6 0.1 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain SMC_N PF02463.19 GAM26682.1 - 0.026 14.0 0.1 23 4.3 0.0 3.4 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 GAM26682.1 - 0.031 14.0 1.0 1.7 8.3 0.2 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAM26682.1 - 0.033 14.2 0.7 1.5 8.9 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 GAM26682.1 - 0.038 13.5 0.2 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 GAM26682.1 - 0.038 13.4 0.5 0.87 9.0 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit cobW PF02492.19 GAM26682.1 - 0.039 13.5 1.8 2 8.0 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 GAM26682.1 - 0.04 14.1 0.3 18 5.6 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 GAM26682.1 - 0.059 12.9 0.5 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAM26682.1 - 0.068 12.4 0.0 4.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 GAM26682.1 - 0.068 13.5 1.0 6.6 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GAM26682.1 - 0.11 12.6 2.2 5.5 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 GAM26682.1 - 0.21 10.6 0.1 24 3.9 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein AAA_17 PF13207.6 GAM26682.1 - 0.26 11.7 0.6 21 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DNA_pol_phi PF04931.13 GAM26683.1 - 2.6e-119 399.6 31.1 2.6e-119 399.6 31.1 4.5 3 2 0 4 4 4 2 DNA polymerase phi BUD22 PF09073.10 GAM26683.1 - 2e-06 27.5 60.7 6.5e-06 25.7 13.1 3.3 3 0 0 3 3 3 3 BUD22 SDA1 PF05285.12 GAM26683.1 - 0.0015 18.0 19.6 0.0015 18.0 19.6 4.1 3 1 1 4 4 4 1 SDA1 TFIIA PF03153.13 GAM26683.1 - 0.0026 17.8 13.2 0.0026 17.8 13.2 3.8 4 0 0 4 4 4 2 Transcription factor IIA, alpha/beta subunit ThiF PF00899.21 GAM26684.1 - 3.4e-55 187.1 0.7 4.9e-55 186.5 0.7 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 GAM26684.1 - 2.3e-08 34.5 0.0 4.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 GAM26684.1 - 0.049 13.7 0.3 0.27 11.3 0.3 2.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 GAM26684.1 - 0.07 12.7 1.4 0.11 12.1 1.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 GAM26684.1 - 0.079 12.5 0.4 0.13 11.8 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 GAM26684.1 - 0.51 9.5 2.9 0.85 8.8 2.9 1.3 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 GAM26684.1 - 6.2 7.1 7.2 66 3.8 6.1 2.7 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HD PF01966.22 GAM26685.1 - 7.1e-07 29.5 0.1 1.2e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 HD domain YscO-like PF16789.5 GAM26685.1 - 0.049 13.7 0.3 0.36 10.8 0.3 2.0 1 1 0 1 1 1 0 YscO-like protein LRR_6 PF13516.6 GAM26686.1 - 0.00011 22.0 18.7 0.35 11.0 0.0 7.3 7 0 0 7 7 7 2 Leucine Rich repeat F-box-like PF12937.7 GAM26686.1 - 0.00057 19.7 0.2 0.0017 18.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 GAM26686.1 - 0.013 15.9 11.1 9.8 7.2 0.0 6.1 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.7 GAM26686.1 - 0.21 12.1 16.6 0.27 11.7 1.3 5.2 3 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Acetyltransf_7 PF13508.7 GAM26687.1 - 1.2e-07 32.0 0.1 1.9e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM26687.1 - 2.6e-07 30.6 0.1 2.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM26687.1 - 1.9e-05 24.9 0.0 2.4e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAM26687.1 - 0.00038 20.4 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAM26687.1 - 0.00056 20.0 0.0 0.0019 18.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 GAM26687.1 - 0.0013 18.4 0.1 0.0031 17.1 0.0 1.6 1 1 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 GAM26687.1 - 0.059 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DNApol_Exo PF18136.1 GAM26687.1 - 0.16 11.1 0.0 1.1 8.4 0.0 1.9 1 1 1 2 2 2 0 DNA mitochondrial polymerase exonuclease domain EF-hand_1 PF00036.32 GAM26688.1 - 3.2e-13 48.2 0.1 4.3e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 GAM26688.1 - 1.4e-11 44.1 0.3 3.2e-07 30.1 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 GAM26688.1 - 4.4e-10 39.9 0.0 5e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM26688.1 - 1e-09 37.5 0.1 1.8e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 GAM26688.1 - 1e-05 25.7 0.0 1.3e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EFhand_Ca_insen PF08726.10 GAM26688.1 - 0.00027 21.0 0.2 0.0005 20.1 0.2 1.5 1 1 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 GAM26688.1 - 0.0061 16.0 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 EF hand DDE_Tnp_IS66_C PF13817.6 GAM26688.1 - 0.042 14.1 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 IS66 C-terminal element Docking PF08990.11 GAM26688.1 - 0.16 11.6 0.2 0.23 11.1 0.2 1.2 1 0 0 1 1 1 0 Erythronolide synthase docking Gal4_dimer PF03902.13 GAM26689.1 - 0.13 12.4 0.4 0.32 11.2 0.4 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain FNIP PF05725.12 GAM26690.1 - 1.4e-67 223.6 18.7 2e-12 47.1 0.1 7.3 3 1 6 9 9 9 9 FNIP Repeat EF-hand_1 PF00036.32 GAM26690.1 - 3.1e-07 29.4 7.3 0.084 12.5 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 GAM26690.1 - 1.7e-06 28.4 4.3 0.0087 16.5 1.1 3.7 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 GAM26690.1 - 2.1e-06 27.5 4.0 0.00048 19.9 1.6 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM26690.1 - 1.3e-05 24.7 7.6 0.61 10.2 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain UBA PF00627.31 GAM26690.1 - 0.0042 17.0 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF1769 PF08588.10 GAM26690.1 - 0.0098 16.1 1.7 2 8.7 0.1 4.6 4 1 1 5 5 5 1 Protein of unknown function (DUF1769) EF-hand_9 PF14658.6 GAM26690.1 - 0.04 14.3 0.0 8.1 6.9 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain COPI_C PF06957.11 GAM26690.1 - 0.42 9.3 8.3 3 6.5 3.3 2.2 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Hexapep PF00132.24 GAM26691.1 - 3.2e-12 45.7 16.0 0.00039 20.0 1.5 4.7 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 GAM26691.1 - 1.7e-06 27.2 0.8 0.0019 17.2 0.1 2.1 1 1 1 2 2 2 2 L-fucokinase Hexapep_2 PF14602.6 GAM26691.1 - 0.00012 21.7 14.5 0.035 13.9 5.2 4.0 2 1 2 4 4 4 4 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 GAM26691.1 - 0.00018 19.8 0.3 0.00022 19.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) SUZ PF12752.7 GAM26692.1 - 8 7.3 7.7 6.2 7.7 2.0 3.0 2 0 0 2 2 2 0 SUZ domain AA_permease_2 PF13520.6 GAM26693.1 - 2.7e-42 145.1 38.0 3.4e-42 144.8 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAM26693.1 - 8.2e-26 90.6 30.7 1.4e-25 89.9 30.7 1.3 1 0 0 1 1 1 1 Amino acid permease DDDD PF10161.9 GAM26693.1 - 0.19 11.5 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Putative mitochondrial precursor protein LUC7 PF03194.15 GAM26694.1 - 4.8e-65 219.7 15.8 6.4e-65 219.3 15.8 1.1 1 0 0 1 1 1 1 LUC7 N_terminus RhlB PF12300.8 GAM26694.1 - 0.021 15.0 3.9 0.021 15.0 3.9 2.7 1 1 2 3 3 3 0 ATP-dependent RNA helicase RhlB GFA PF04828.14 GAM26694.1 - 0.044 14.1 0.5 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme UPF0160 PF03690.13 GAM26694.1 - 0.29 10.7 3.5 0.41 10.2 3.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Prok-RING_1 PF14446.6 GAM26694.1 - 2.6 8.0 6.4 4.3 7.3 3.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 V_ATPase_I PF01496.19 GAM26694.1 - 6.8 4.5 5.9 9.4 4.0 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_19 PF14559.6 GAM26695.1 - 7.2e-08 32.8 0.4 0.0046 17.4 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM26695.1 - 0.00021 21.8 1.6 1.4 10.0 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM26695.1 - 0.00031 20.6 2.6 0.087 13.0 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAM26695.1 - 0.002 18.2 0.4 0.084 13.1 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM26695.1 - 0.0033 17.7 0.2 1.5 9.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAM26695.1 - 0.0036 17.0 2.9 0.26 11.2 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM26695.1 - 0.012 15.9 1.2 0.85 10.0 0.1 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM26695.1 - 0.033 14.8 1.8 2.3 9.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4919 PF16266.5 GAM26695.1 - 0.054 13.4 0.2 3.3 7.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4919) TPR_16 PF13432.6 GAM26695.1 - 0.13 13.0 0.3 31 5.3 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM26695.1 - 0.69 10.1 3.9 5.9 7.2 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 GAM26696.1 - 1.6e-09 38.1 0.1 0.17 12.2 0.0 6.3 5 0 0 5 5 5 2 AAA domain AAA_7 PF12775.7 GAM26696.1 - 1.5e-07 31.1 3.3 0.43 10.1 0.0 5.0 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA PF00004.29 GAM26696.1 - 8.6e-07 29.4 5.5 0.0012 19.3 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM26696.1 - 1.2e-06 29.0 0.0 0.057 13.8 0.0 4.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 GAM26696.1 - 6e-06 26.3 0.0 3.4 7.7 0.0 5.2 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 GAM26696.1 - 0.0095 15.7 0.0 1.6 8.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 GAM26696.1 - 0.018 14.1 1.4 0.19 10.7 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_25 PF13481.6 GAM26696.1 - 0.049 13.2 0.1 2.7 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 GAM26696.1 - 0.089 12.6 0.0 1 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAM26696.1 - 0.098 12.6 0.0 4.8 7.1 0.0 3.0 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 GAM26696.1 - 0.1 12.3 0.2 6.9 6.5 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 GAM26696.1 - 0.11 12.2 0.8 16 5.2 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein Zn-ribbon_8 PF09723.10 GAM26696.1 - 0.23 11.6 2.1 6.9 6.9 0.1 3.0 3 0 0 3 3 3 0 Zinc ribbon domain FNIP PF05725.12 GAM26697.1 - 2.4e-23 82.0 4.8 3.4e-09 36.7 0.1 4.9 4 1 1 5 5 5 4 FNIP Repeat zf-RanBP PF00641.18 GAM26698.1 - 0.0013 18.0 3.1 0.0026 17.1 3.1 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DZR PF12773.7 GAM26698.1 - 0.0028 17.6 0.5 0.0041 17.1 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 GAM26698.1 - 0.0053 16.4 5.2 0.0087 15.7 5.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 GAM26698.1 - 0.015 16.0 0.2 0.026 15.3 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon family Sel1 PF08238.12 GAM26700.1 - 1.2e-28 98.8 8.0 4.4e-08 33.6 0.1 6.4 6 1 0 6 6 6 5 Sel1 repeat Ndc1_Nup PF09531.10 GAM26700.1 - 0.22 10.2 3.4 0.27 9.9 3.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2678 PF10856.8 GAM26701.1 - 2.7e-07 30.5 0.2 3.9e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) DUF2427 PF10348.9 GAM26701.1 - 0.037 13.8 1.1 0.072 12.9 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) DUF805 PF05656.14 GAM26701.1 - 0.057 13.8 0.4 0.069 13.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) SPC25 PF06703.11 GAM26701.1 - 1.8 8.4 3.5 6.4 6.5 0.6 2.1 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) RGP PF03214.13 GAM26702.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide Zn-ribbon_8 PF09723.10 GAM26702.1 - 0.55 10.4 15.0 0.62 10.2 0.3 4.2 4 0 0 4 4 4 0 Zinc ribbon domain Pkinase_Tyr PF07714.17 GAM26703.1 - 3.6e-68 229.7 0.0 4.7e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM26703.1 - 3e-55 187.4 0.0 4.2e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 GAM26703.1 - 2e-10 40.6 0.0 4.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 GAM26703.1 - 0.00054 20.0 0.0 0.0016 18.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM26703.1 - 0.00059 18.9 0.0 0.0013 17.7 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Cbl_N2 PF02761.14 GAM26703.1 - 0.014 16.1 0.1 0.079 13.7 0.1 2.1 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain Pkinase_fungal PF17667.1 GAM26703.1 - 0.041 12.6 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 GAM26703.1 - 0.13 11.9 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1467 PF07330.12 GAM26704.1 - 0.014 15.3 0.1 3.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) EI24 PF07264.11 GAM26704.1 - 0.027 14.7 0.0 0.062 13.5 0.0 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF1270 PF06900.11 GAM26704.1 - 1.6 9.2 6.5 16 6.0 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) Ras PF00071.22 GAM26707.1 - 1.2e-53 181.0 0.0 1.5e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM26707.1 - 3.9e-24 85.2 0.0 5.7e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM26707.1 - 5.4e-07 29.2 0.0 1.4e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM26707.1 - 0.00037 20.1 0.0 0.00065 19.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain T3SchapCesA PF11439.8 GAM26707.1 - 0.067 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA ArfGap PF01412.18 GAM26708.1 - 1.8e-41 140.9 0.3 1.1e-40 138.3 0.3 2.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 GAM26708.1 - 5.3e-23 82.0 10.4 5.3e-23 82.0 10.4 1.9 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 GAM26708.1 - 1.1e-17 64.5 0.1 2.4e-17 63.4 0.1 1.7 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 GAM26708.1 - 9.8e-10 38.8 0.0 0.00028 21.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM26708.1 - 1.2e-09 38.6 0.0 5.4e-07 30.1 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) BAR PF03114.18 GAM26708.1 - 3.1e-09 36.8 9.3 3.1e-09 36.8 9.3 2.2 2 0 0 2 2 2 1 BAR domain Ank_5 PF13857.6 GAM26708.1 - 1.9e-06 28.0 0.2 4.6e-05 23.6 0.0 2.9 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM26708.1 - 3.9e-06 27.0 0.0 0.83 10.2 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat PH_11 PF15413.6 GAM26708.1 - 0.00015 22.1 0.4 0.0013 19.1 0.0 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_3 PF13606.6 GAM26708.1 - 0.00016 21.8 0.6 1.9 9.3 0.0 3.8 5 0 0 5 5 2 2 Ankyrin repeat PH_13 PF16652.5 GAM26708.1 - 0.0078 16.0 0.1 0.026 14.4 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 GAM26708.1 - 0.038 14.4 1.2 0.11 12.8 0.1 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain PH_4 PF15404.6 GAM26708.1 - 0.045 13.5 4.2 0.085 12.7 0.0 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain IMD PF08397.11 GAM26708.1 - 0.092 12.1 4.6 0.22 10.9 4.6 1.6 1 0 0 1 1 1 0 IRSp53/MIM homology domain Gln-synt_N PF03951.19 GAM26708.1 - 0.16 11.7 0.3 3.3 7.5 0.1 2.7 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain TPR_MLP1_2 PF07926.12 GAM26708.1 - 0.88 9.6 9.7 0.26 11.3 5.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein NST1 PF13945.6 GAM26709.1 - 5.9 7.0 22.0 0.91 9.6 8.2 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator SCAI PF12070.8 GAM26710.1 - 0.005 15.8 0.1 0.0079 15.1 0.1 1.2 1 0 0 1 1 1 1 Protein SCAI DDE_5 PF13546.6 GAM26710.1 - 0.039 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Peptidase_C9 PF01707.16 GAM26711.1 - 0.055 13.1 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C9 Antimicrobial_1 PF08018.11 GAM26711.1 - 0.088 13.0 0.3 0.16 12.2 0.3 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide LRR_10 PF18805.1 GAM26711.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat HSP70 PF00012.20 GAM26712.1 - 3e-68 230.5 0.7 4.3e-61 206.9 0.5 2.2 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 GAM26712.1 - 9.5e-07 27.9 0.0 2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein DUF2722 PF10846.8 GAM26712.1 - 0.025 13.6 1.9 0.033 13.2 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RAI16-like PF10257.9 GAM26712.1 - 0.096 11.5 0.7 0.14 11.0 0.7 1.1 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein FtsA PF14450.6 GAM26712.1 - 0.16 12.4 0.3 1.4 9.4 0.0 2.4 2 1 0 2 2 2 0 Cell division protein FtsA HSP70 PF00012.20 GAM26713.1 - 7.9e-125 417.3 0.0 1e-124 417.0 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM26713.1 - 3.2e-08 32.8 0.0 2.7e-07 29.7 0.0 2.3 3 0 0 3 3 3 1 MreB/Mbl protein WD-3 PF09765.9 GAM26713.1 - 0.0048 16.3 0.5 0.01 15.2 0.5 1.5 1 0 0 1 1 1 1 WD-repeat region B5 PF03484.15 GAM26713.1 - 0.15 12.3 0.0 0.63 10.4 0.0 2.0 1 0 0 1 1 1 0 tRNA synthetase B5 domain DUF2603 PF10788.9 GAM26713.1 - 0.62 10.1 0.0 0.62 10.1 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2603) Syja_N PF02383.18 GAM26714.1 - 1.9e-79 267.3 0.2 1.9e-79 267.3 0.2 2.4 3 0 0 3 3 3 1 SacI homology domain WYL PF13280.6 GAM26714.1 - 0.031 14.3 0.0 0.085 12.9 0.0 1.7 1 0 0 1 1 1 0 WYL domain Tir_receptor_C PF07489.11 GAM26714.1 - 1.6 8.7 13.4 4.5 7.2 13.4 1.8 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus TIG PF01833.24 GAM26715.1 - 1.9e-14 53.5 22.6 0.00017 21.6 0.3 5.7 6 0 0 6 6 6 4 IPT/TIG domain EGF_2 PF07974.13 GAM26715.1 - 0.00027 21.2 6.2 0.00064 20.0 6.2 1.7 1 0 0 1 1 1 1 EGF-like domain Lectin_C PF00059.21 GAM26715.1 - 0.017 15.8 0.0 0.21 12.3 0.0 2.6 2 1 0 2 2 2 0 Lectin C-type domain EGF PF00008.27 GAM26715.1 - 0.28 11.5 4.0 0.73 10.2 4.0 1.8 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 GAM26715.1 - 1.6 9.5 7.6 5.7 7.7 7.6 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF Kelch_3 PF13415.6 GAM26716.1 - 1.6e-29 101.5 21.7 1.9e-05 24.8 0.1 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM26716.1 - 1e-28 99.1 27.2 1.2e-07 31.6 0.1 6.7 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM26716.1 - 5.5e-26 90.1 11.2 1.9e-06 27.7 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAM26716.1 - 5.2e-22 77.3 17.6 0.00031 20.9 0.1 6.6 6 1 1 7 7 7 6 Kelch motif Kelch_1 PF01344.25 GAM26716.1 - 2.6e-16 58.9 17.7 0.00015 21.3 0.0 6.7 7 0 0 7 7 7 5 Kelch motif Kelch_2 PF07646.15 GAM26716.1 - 4.8e-11 42.2 4.9 0.21 11.6 0.0 5.8 5 0 0 5 5 5 4 Kelch motif 7TM_GPCR_Srd PF10317.9 GAM26716.1 - 0.063 12.5 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Rep-A_N PF04057.12 GAM26718.1 - 0.042 13.9 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain Popeye PF04831.13 GAM26718.1 - 0.11 12.6 0.1 0.32 11.2 0.1 1.7 2 0 0 2 2 2 0 Popeye protein conserved region Mlh1_C PF16413.5 GAM26719.1 - 8.2e-83 277.9 1.9 1.1e-82 277.4 0.0 2.2 3 0 0 3 3 3 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 GAM26719.1 - 7.6e-29 99.8 0.2 2.6e-28 98.1 0.2 2.0 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAM26719.1 - 8.7e-11 41.8 0.0 8.7e-11 41.8 0.0 2.7 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAM26719.1 - 6.2e-07 29.9 0.0 2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GOLD_2 PF13897.6 GAM26719.1 - 0.18 12.3 0.1 0.18 12.3 0.1 2.7 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking Aminotran_1_2 PF00155.21 GAM26720.1 - 3.7e-16 59.2 0.0 2.6e-09 36.8 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Aminotran_MocR PF12897.7 GAM26720.1 - 0.001 17.9 0.0 0.057 12.2 0.0 2.0 1 1 1 2 2 2 2 Alanine-glyoxylate amino-transferase Glyco_transf_20 PF00982.21 GAM26721.1 - 2.5e-186 620.0 0.0 3.1e-186 619.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAM26721.1 - 1.3e-35 122.6 0.0 2.3e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 GAM26721.1 - 1e-05 25.2 0.5 8.3e-05 22.2 0.3 2.5 2 1 0 2 2 2 1 Glycosyl transferases group 1 Complex1_LYR PF05347.15 GAM26722.1 - 2.4e-08 33.9 0.1 4.7e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) BRD4_CDT PF17105.5 GAM26722.1 - 0.01 15.4 2.1 0.021 14.4 2.1 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 DUF2870 PF11069.8 GAM26722.1 - 0.024 15.0 1.0 0.044 14.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Complex1_LYR_2 PF13233.6 GAM26722.1 - 0.057 14.2 1.0 0.12 13.1 1.0 1.7 1 1 0 1 1 1 0 Complex1_LYR-like DNA_pol_A_exo1 PF01612.20 GAM26723.1 - 4.9e-28 98.0 0.0 7.1e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease GTP_EFTU PF00009.27 GAM26724.1 - 1.1e-13 51.2 0.0 2.6e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAM26724.1 - 7.7e-11 41.9 0.0 2.2e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 GAM26724.1 - 1.5e-10 40.9 0.0 5.5e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 GAM26724.1 - 0.029 14.8 0.6 4.3 7.8 0.0 2.6 1 1 1 2 2 2 0 Elongation factor Tu domain 2 DUF5546 PF17700.1 GAM26724.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5546) ketoacyl-synt PF00109.26 GAM26726.1 - 8.5e-69 231.9 0.0 1.5e-68 231.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAM26726.1 - 2.6e-49 168.5 0.0 1e-48 166.5 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAM26726.1 - 2.8e-37 127.3 0.1 5.8e-37 126.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 GAM26726.1 - 1.4e-33 116.4 0.5 3.2e-33 115.2 0.5 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 GAM26726.1 - 4.9e-27 95.0 0.0 8.7e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 GAM26726.1 - 2.3e-17 63.4 0.0 7.3e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 GAM26726.1 - 2e-07 31.3 0.1 5.9e-07 29.7 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 GAM26726.1 - 3.5e-05 23.3 0.0 9.3e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.12 GAM26726.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DENN PF02141.21 GAM26728.1 - 5.7e-29 101.4 1.2 1.5e-28 100.0 1.2 1.8 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAM26728.1 - 8.6e-08 32.8 0.4 8.6e-08 32.8 0.4 3.3 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 GAM26728.1 - 0.013 15.4 0.9 0.044 13.8 0.9 1.8 1 0 0 1 1 1 0 dDENN domain Cofilin_ADF PF00241.20 GAM26729.1 - 0.041 13.7 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein SUIM_assoc PF16619.5 GAM26729.1 - 0.049 13.7 4.2 0.13 12.3 4.2 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PWWP PF00855.17 GAM26730.1 - 1e-08 35.5 0.1 1e-08 35.5 0.1 2.9 3 0 0 3 3 3 1 PWWP domain DUF5617 PF18493.1 GAM26730.1 - 0.0057 16.7 1.7 0.02 15.0 1.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5617) DUF2624 PF11116.8 GAM26730.1 - 0.047 14.6 0.4 0.21 12.5 0.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) DUF5499 PF17603.2 GAM26730.1 - 0.19 12.4 4.7 4.9 7.8 0.9 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5499) Dna2 PF08696.11 GAM26730.1 - 0.45 10.3 6.6 0.075 12.8 2.1 2.0 2 0 0 2 2 2 0 DNA replication factor Dna2 PNPase PF03726.14 GAM26730.1 - 0.77 10.3 8.8 0.3 11.6 1.5 3.3 2 1 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Prominin PF05478.11 GAM26730.1 - 3.3 5.6 11.6 0.78 7.6 7.8 1.8 2 0 0 2 2 2 0 Prominin RGS PF00615.19 GAM26731.1 - 1.5e-28 99.4 3.9 2e-28 99.0 3.9 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Gly_radical PF01228.21 GAM26731.1 - 0.037 14.6 0.1 0.065 13.8 0.1 1.3 1 0 0 1 1 1 0 Glycine radical FTR_C PF02741.15 GAM26733.1 - 0.12 12.3 0.0 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 FTR, proximal lobe DUF2244 PF10003.9 GAM26733.1 - 0.14 11.9 0.6 0.34 10.6 0.6 1.6 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) RCC1 PF00415.18 GAM26734.1 - 2e-64 214.0 11.1 3.7e-12 46.7 0.0 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM26734.1 - 2.7e-48 160.9 31.4 1.3e-10 40.8 0.7 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.18 GAM26734.1 - 1.3e-43 149.2 1.0 2.1e-43 148.5 0.3 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.32 GAM26735.1 - 3.8e-19 68.7 1.0 0.021 15.7 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM26735.1 - 3e-08 33.8 0.0 0.0002 21.6 0.0 3.5 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM26735.1 - 1.1e-07 31.5 1.4 5.2e-07 29.3 0.8 2.0 1 1 1 2 2 2 1 WD40-like domain Cytochrom_D1 PF02239.16 GAM26735.1 - 8.2e-06 24.6 0.4 0.012 14.2 0.2 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_3 PF13570.6 GAM26735.1 - 0.00016 22.0 0.1 4.7 7.8 0.0 4.1 5 0 0 5 5 4 1 PQQ-like domain Nup160 PF11715.8 GAM26735.1 - 0.00092 18.0 0.1 0.41 9.2 0.0 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 GAM26735.1 - 0.0074 16.3 0.1 0.56 10.3 0.1 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 GAM26735.1 - 0.012 15.3 0.0 1.1e+02 2.2 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain Frtz PF11768.8 GAM26735.1 - 0.075 11.3 0.0 1.5 7.0 0.0 2.4 1 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz BUD22 PF09073.10 GAM26735.1 - 0.3 10.4 29.3 0.46 9.8 29.3 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GAM26735.1 - 0.52 8.5 30.8 0.69 8.1 30.8 1.1 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 GAM26735.1 - 0.62 9.5 21.3 0.94 8.9 21.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein SDA1 PF05285.12 GAM26735.1 - 1.5 8.1 34.2 2.2 7.6 34.2 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GAM26735.1 - 6.3 6.5 29.8 11 5.6 29.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GAM26735.1 - 7.4 4.7 26.4 12 4.1 26.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Pyr_redox_2 PF07992.14 GAM26736.1 - 3.9e-67 226.6 1.1 5.1e-67 226.2 1.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAM26736.1 - 9.6e-32 109.5 0.2 2.2e-31 108.4 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 GAM26736.1 - 1.5e-20 73.7 3.2 2.5e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM26736.1 - 5.8e-20 71.6 7.2 5.7e-19 68.5 0.4 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM26736.1 - 3.4e-06 26.7 0.7 9.5e-05 21.9 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM26736.1 - 9.7e-06 24.5 3.0 0.093 11.4 0.5 3.4 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 GAM26736.1 - 0.00045 19.4 7.7 0.00054 19.2 0.7 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A K_oxygenase PF13434.6 GAM26736.1 - 0.00078 18.7 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAM26736.1 - 0.0017 18.6 1.8 0.007 16.6 1.8 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 GAM26736.1 - 0.0053 16.1 0.3 0.9 8.9 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 GAM26736.1 - 0.0081 15.8 11.9 0.34 10.5 2.2 3.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAM26736.1 - 0.0088 15.4 0.8 1.7 7.9 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 GAM26736.1 - 0.046 12.9 2.0 1.5 7.9 0.4 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 GAM26736.1 - 0.054 12.7 0.1 0.14 11.4 0.1 1.7 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 GAM26736.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 GAM26736.1 - 0.16 12.4 0.3 2 9.0 0.1 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_binding_2 PF00890.24 GAM26736.1 - 0.19 10.8 6.2 0.73 8.8 1.6 2.9 4 0 0 4 4 4 0 FAD binding domain Peptidase_M22 PF00814.25 GAM26738.1 - 7.7e-86 288.2 0.0 8.7e-86 288.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family zf-CHCC PF10276.9 GAM26739.1 - 4.6e-18 65.0 1.7 6.5e-18 64.5 1.7 1.2 1 0 0 1 1 1 1 Zinc-finger domain Pro_isomerase PF00160.21 GAM26740.1 - 3.6e-54 183.3 0.1 4e-54 183.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 GAM26740.1 - 0.031 14.0 0.0 0.064 12.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) Metallophos PF00149.28 GAM26741.1 - 3.5e-09 37.5 0.7 5.9e-09 36.7 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IU_nuc_hydro PF01156.19 GAM26742.1 - 1.9e-64 218.2 0.7 2.3e-64 217.9 0.7 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.22 GAM26743.1 - 1.8e-92 310.5 0.3 2e-92 310.4 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAM26744.1 - 6.3e-76 256.0 0.2 7e-76 255.8 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 BRCT_2 PF16589.5 GAM26745.1 - 3e-08 34.0 0.1 3e-08 34.0 0.1 3.0 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAM26745.1 - 2e-07 31.3 0.1 2e-07 31.3 0.1 2.8 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain RRM_1 PF00076.22 GAM26745.1 - 0.0058 16.4 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTCB-BRCT PF12738.7 GAM26745.1 - 0.12 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain RNA_bind PF08675.11 GAM26745.1 - 0.12 12.4 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 RNA binding domain Nup35_RRM_2 PF14605.6 GAM26745.1 - 0.16 12.0 0.1 0.4 10.7 0.1 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Cpn60_TCP1 PF00118.24 GAM26746.1 - 9.2e-151 502.8 13.1 1e-150 502.6 13.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FA_desaturase PF00487.24 GAM26747.1 - 8.7e-20 71.6 18.9 8.7e-20 71.6 18.9 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.10 GAM26747.1 - 0.0044 16.5 0.2 0.009 15.5 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Metalloenzyme PF01676.18 GAM26748.1 - 4.6e-21 75.3 0.0 5.6e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily PhosphMutase PF10143.9 GAM26748.1 - 3.4e-13 49.8 0.0 5.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Phosphodiest PF01663.22 GAM26748.1 - 0.016 14.8 0.0 0.034 13.8 0.0 1.6 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase PhosphMutase PF10143.9 GAM26749.1 - 2.4e-25 89.3 0.1 2.8e-25 89.2 0.1 1.1 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 GAM26749.1 - 0.0042 16.5 0.0 0.0042 16.5 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF5102 PF17104.5 GAM26750.1 - 9.1e-05 22.6 3.8 9.1e-05 22.6 3.8 9.5 3 3 6 9 9 9 4 Domain of unknown function (DUF5102) GTP_EFTU PF00009.27 GAM26751.1 - 2.3e-61 206.8 0.0 3.2e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAM26751.1 - 2.5e-23 82.1 0.0 1e-22 80.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 GAM26751.1 - 6.8e-18 64.5 0.0 2e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAM26751.1 - 1.9e-11 44.2 0.0 5.2e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAM26751.1 - 9.5e-08 32.0 0.0 2.4e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 GAM26751.1 - 0.00064 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF4347 PF14252.6 GAM26751.1 - 0.054 13.3 0.1 0.15 11.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) FNIP PF05725.12 GAM26752.1 - 9.7e-93 304.1 17.0 7.1e-13 48.5 0.1 8.9 5 2 4 9 9 9 9 FNIP Repeat NAR PF16251.5 GAM26752.1 - 5e-07 30.4 0.2 46 4.7 0.0 7.3 3 1 4 8 8 8 0 Nucleic acid-binding domain (NAR) LRR_5 PF13306.6 GAM26752.1 - 0.0002 21.3 1.6 0.038 14.0 0.2 3.4 2 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) GCV_T_C PF08669.11 GAM26752.1 - 0.016 15.1 0.0 15 5.6 0.0 4.1 2 2 2 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain FNIP PF05725.12 GAM26754.1 - 2.1e-63 210.3 4.4 6e-10 39.1 0.1 6.3 2 1 4 6 6 6 6 FNIP Repeat LRR_5 PF13306.6 GAM26754.1 - 2.6e-05 24.2 0.0 0.028 14.4 0.0 3.4 1 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Inp1 PF12634.7 GAM26754.1 - 0.32 11.0 2.1 72 3.4 0.0 4.4 2 1 1 4 4 4 0 Inheritance of peroxisomes protein 1 GTP_EFTU PF00009.27 GAM26756.1 - 5.4e-51 172.9 0.0 7.7e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAM26756.1 - 1.2e-20 73.4 0.0 5.8e-20 71.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 GAM26756.1 - 3.2e-18 65.5 0.0 7.9e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAM26756.1 - 2.1e-11 44.0 0.0 5e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAM26756.1 - 2.8e-08 33.7 0.0 6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 GAM26756.1 - 0.0001 22.1 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF2551 PF10826.8 GAM26756.1 - 0.064 13.5 0.5 6.2 7.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2551) SRPRB PF09439.10 GAM26756.1 - 0.14 11.6 0.0 0.41 10.1 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FNIP PF05725.12 GAM26758.1 - 1.3e-81 268.5 15.9 5.1e-14 52.2 0.1 7.2 6 1 1 7 7 7 7 FNIP Repeat GCV_T_C PF08669.11 GAM26758.1 - 0.17 11.8 0.0 29 4.7 0.0 3.2 1 1 1 3 3 3 0 Glycine cleavage T-protein C-terminal barrel domain 2OG-FeII_Oxy_3 PF13640.6 GAM26759.1 - 2.6e-15 57.1 0.0 4.1e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAM26759.1 - 0.00024 21.6 0.0 0.00038 20.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP-synt_J PF04911.12 GAM26760.1 - 0.029 13.9 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase j chain SNARE PF05739.19 GAM26761.1 - 1.3e-10 41.1 0.5 2.2e-10 40.4 0.5 1.3 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 GAM26761.1 - 0.0046 15.0 0.2 0.005 14.9 0.2 1.0 1 0 0 1 1 1 1 Prominin RAMP4 PF06624.12 GAM26762.1 - 3.5e-18 65.4 0.1 4.3e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 3-dmu-9_3-mt PF06983.13 GAM26762.1 - 0.052 14.1 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase Mit_KHE1 PF10173.9 GAM26764.1 - 1.3e-32 113.4 4.1 3.5e-32 112.0 4.0 1.7 1 1 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF3470 PF11953.8 GAM26764.1 - 0.16 12.0 0.2 0.37 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3470) TPR_1 PF00515.28 GAM26765.1 - 1.9e-12 46.4 0.0 0.00032 20.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM26765.1 - 6e-10 38.5 0.0 0.0039 17.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAM26765.1 - 5.7e-06 25.9 0.0 0.063 13.0 0.0 2.9 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 GAM26765.1 - 0.0016 18.5 0.0 0.023 14.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM26765.1 - 0.13 13.1 0.0 0.42 11.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat FNIP PF05725.12 GAM26766.1 - 6.4e-13 48.6 18.5 2.9e-07 30.6 0.1 5.7 4 1 2 7 7 7 4 FNIP Repeat AAA_12 PF13087.6 GAM26767.1 - 8.4e-56 188.8 0.1 2.4e-55 187.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM26767.1 - 1.4e-51 175.8 3.4 3.2e-28 99.2 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 GAM26767.1 - 3.3e-12 47.0 0.0 1.1e-11 45.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain PAP_assoc PF03828.19 GAM26767.1 - 2e-11 43.9 0.6 2.1e-10 40.7 0.1 2.6 2 0 0 2 2 2 1 Cid1 family poly A polymerase AAA_30 PF13604.6 GAM26767.1 - 1.5e-10 41.2 0.0 5.9e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 GAM26767.1 - 3.1e-07 30.4 1.2 0.02 14.6 0.0 4.1 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 GAM26767.1 - 3e-05 23.7 1.1 0.015 14.8 0.0 3.6 4 1 1 5 5 5 1 UvrD/REP helicase N-terminal domain NTP_transf_2 PF01909.23 GAM26767.1 - 0.00082 19.6 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain ResIII PF04851.15 GAM26767.1 - 0.0014 18.7 0.0 0.0087 16.1 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 GAM26767.1 - 0.0028 17.5 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF4269 PF14091.6 GAM26767.1 - 0.0089 16.3 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4269) AAA_22 PF13401.6 GAM26767.1 - 0.018 15.3 0.1 0.14 12.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain Seipin PF06775.14 GAM26767.1 - 0.023 14.8 0.9 0.052 13.7 0.9 1.5 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) Helicase_RecD PF05127.14 GAM26767.1 - 0.049 13.5 0.0 0.3 10.9 0.0 2.4 1 1 0 1 1 1 0 Helicase Polbeta PF18765.1 GAM26767.1 - 0.056 13.5 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase AAA_16 PF13191.6 GAM26767.1 - 0.072 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF1451 PF07295.11 GAM26767.1 - 0.27 11.2 1.8 0.63 10.1 1.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF2075 PF09848.9 GAM26767.1 - 0.81 8.9 4.5 0.47 9.6 0.0 2.6 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ADAM_spacer1 PF05986.14 GAM26768.1 - 0.25 11.4 2.3 1.5 8.9 0.6 2.0 1 1 1 2 2 2 0 ADAM-TS Spacer 1 AAA_11 PF13086.6 GAM26769.1 - 5.5e-54 183.7 16.7 3e-28 99.4 0.0 4.3 3 1 1 4 4 4 2 AAA domain AAA_12 PF13087.6 GAM26769.1 - 9.8e-54 182.0 0.0 3e-53 180.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM26769.1 - 2.7e-13 50.1 0.0 7.7e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain PAP_assoc PF03828.19 GAM26769.1 - 6.9e-12 45.4 0.2 1.9e-11 44.0 0.2 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase AAA_19 PF13245.6 GAM26769.1 - 8e-12 45.7 0.0 2.4e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Nrap_D2 PF17403.2 GAM26769.1 - 4.8e-07 29.7 0.0 1.5e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain NTP_transf_2 PF01909.23 GAM26769.1 - 6e-06 26.5 0.0 1.8e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain AAA_22 PF13401.6 GAM26769.1 - 0.00029 21.1 1.0 0.0045 17.3 0.0 3.2 3 1 0 3 3 3 1 AAA domain Polbeta PF18765.1 GAM26769.1 - 0.00041 20.4 0.0 0.0019 18.3 0.0 2.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase ResIII PF04851.15 GAM26769.1 - 0.00043 20.3 0.0 0.0067 16.4 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 GAM26769.1 - 0.00049 19.9 0.2 12 5.5 0.0 3.8 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 GAM26769.1 - 0.0068 16.8 2.1 0.17 12.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Helicase_RecD PF05127.14 GAM26769.1 - 0.015 15.2 0.0 0.086 12.7 0.0 2.4 1 1 0 1 1 1 0 Helicase PhoH PF02562.16 GAM26769.1 - 0.018 14.5 0.1 0.059 12.8 0.1 1.9 1 1 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 GAM26769.1 - 0.034 13.9 0.0 0.099 12.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Med3 PF11593.8 GAM26769.1 - 0.039 13.1 2.6 0.099 11.8 2.6 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal T2SSE PF00437.20 GAM26769.1 - 0.045 12.8 0.1 0.2 10.7 0.1 2.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Mito_fiss_reg PF05308.11 GAM26769.1 - 0.29 11.2 4.9 0.71 9.9 4.9 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA PF00004.29 GAM26769.1 - 2.7 8.4 5.6 1.1 9.7 0.1 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Amidohydro_2 PF04909.14 GAM26770.1 - 6.6e-12 45.8 0.0 1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Ank_3 PF13606.6 GAM26771.1 - 0.052 14.1 1.5 33 5.5 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat Homeobox_KN PF05920.11 GAM26772.1 - 1.6e-17 63.1 1.7 3.6e-17 62.0 1.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAM26772.1 - 8.1e-08 32.0 0.3 8.1e-08 32.0 0.3 2.2 3 0 0 3 3 3 1 Homeodomain TMF_DNA_bd PF12329.8 GAM26772.1 - 0.017 15.1 0.6 0.069 13.2 0.6 2.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TBP PF00352.21 GAM26774.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) MCM PF00493.23 GAM26775.1 - 4.7e-99 330.0 0.0 3.4e-98 327.2 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 GAM26775.1 - 3.6e-34 117.3 0.3 6.9e-34 116.4 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAM26775.1 - 5.5e-20 71.6 0.2 2.3e-19 69.6 0.0 2.2 2 0 0 2 2 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 GAM26775.1 - 2.2e-08 33.7 0.1 3.8e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 GAM26775.1 - 5.2e-08 33.4 2.0 9e-07 29.4 1.1 3.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 GAM26775.1 - 1.6e-06 28.1 0.0 7.5e-06 26.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAM26775.1 - 0.0025 17.7 0.1 0.024 14.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2722 PF10846.8 GAM26775.1 - 0.0039 16.2 2.6 0.0061 15.6 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) AAA_lid_2 PF17863.1 GAM26775.1 - 0.02 14.7 0.6 0.073 12.9 0.6 1.9 1 0 0 1 1 1 0 AAA lid domain Neurokinin_B PF03823.14 GAM26775.1 - 0.025 14.6 5.0 9.1 6.4 0.0 2.7 2 0 0 2 2 2 0 Neurokinin B zf-HYPF PF07503.12 GAM26775.1 - 0.33 10.8 1.9 4 7.3 0.2 2.6 2 0 0 2 2 2 0 HypF finger AAA_16 PF13191.6 GAM26775.1 - 0.42 11.0 2.9 0.84 10.0 0.1 2.9 2 1 0 2 2 2 0 AAA ATPase domain Spt20 PF12090.8 GAM26775.1 - 4.8 6.7 17.0 9 5.8 17.0 1.4 1 0 0 1 1 1 0 Spt20 family Peptidase_M48_N PF16491.5 GAM26776.1 - 0.25 11.2 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices SdrD_B PF17210.3 GAM26777.1 - 1.4e-29 102.6 27.8 2.7e-06 27.6 0.5 35.2 13 1 15 34 34 34 11 SdrD B-like domain DUF2012 PF09430.10 GAM26777.1 - 1.1e-05 25.5 0.1 21 5.2 0.0 7.3 7 0 0 7 7 7 1 Protein of unknown function (DUF2012) SPRR2 PF14820.6 GAM26777.1 - 3.4 7.8 8.4 6.8 6.9 8.4 1.4 1 0 0 1 1 1 0 Small proline-rich 2 DENN PF02141.21 GAM26778.1 - 1.5e-41 142.5 4.4 3.3e-41 141.3 4.4 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain WD40 PF00400.32 GAM26778.1 - 1e-36 124.2 32.0 0.00021 22.0 0.3 9.2 8 0 0 8 8 8 8 WD domain, G-beta repeat uDENN PF03456.18 GAM26778.1 - 3e-12 47.1 0.0 9.1e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 uDENN domain ANAPC4_WD40 PF12894.7 GAM26778.1 - 1.6e-06 28.3 4.2 1.5 9.2 0.0 4.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain SBF2 PF12335.8 GAM26778.1 - 1.8e-05 24.5 1.4 3.8e-05 23.4 1.4 1.5 1 0 0 1 1 1 1 Myotubularin protein PQQ_3 PF13570.6 GAM26778.1 - 0.0018 18.7 0.1 15 6.2 0.0 4.5 4 0 0 4 4 4 1 PQQ-like domain Rubrerythrin PF02915.17 GAM26778.1 - 0.18 12.2 1.3 0.27 11.6 0.3 1.8 2 0 0 2 2 2 0 Rubrerythrin DUF2838 PF10998.8 GAM26779.1 - 2e-36 124.6 9.5 2e-36 124.6 9.5 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) DUF2207 PF09972.9 GAM26779.1 - 0.0063 15.3 0.2 0.23 10.2 0.0 2.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) DUF4238 PF14022.6 GAM26779.1 - 0.011 15.2 1.4 0.019 14.5 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Nup54 PF13874.6 GAM26779.1 - 0.035 14.2 0.4 0.065 13.3 0.4 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4628 PF15429.6 GAM26779.1 - 0.97 9.1 14.6 0.011 15.4 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) Occludin_ELL PF07303.13 GAM26779.1 - 2.9 8.6 6.4 3.4 8.5 0.3 3.1 2 1 1 3 3 3 0 Occludin homology domain Mucin PF01456.17 GAM26779.1 - 3.7 7.5 19.1 0.37 10.8 2.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Kelch_6 PF13964.6 GAM26780.1 - 0.019 15.3 4.4 1.7 9.0 0.0 3.8 4 1 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 GAM26780.1 - 0.022 14.7 0.7 9.7 6.3 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Syntaxin PF00804.25 GAM26780.1 - 0.071 12.8 2.0 0.11 12.1 2.0 1.4 1 0 0 1 1 1 0 Syntaxin RPW8 PF05659.11 GAM26780.1 - 0.096 12.4 2.0 2.9 7.6 0.4 2.8 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Baculo_PEP_C PF04513.12 GAM26780.1 - 0.1 12.6 1.9 0.15 12.1 1.0 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliT PF05400.13 GAM26780.1 - 0.11 13.3 0.1 0.26 12.1 0.1 1.5 1 0 0 1 1 1 0 Flagellar protein FliT Ribosomal_L7Ae PF01248.26 GAM26782.1 - 6.5e-25 86.7 2.1 8.3e-25 86.4 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family V_ATPase_I PF01496.19 GAM26783.1 - 1.9 6.3 22.0 2.2 6.1 22.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GvpK PF05121.12 GAM26783.1 - 2.4 8.3 7.0 0.65 10.1 1.6 2.4 2 0 0 2 2 2 0 Gas vesicle protein K MICSWaP PF17018.5 GAM26783.1 - 6.4 6.3 12.8 0.74 9.3 1.8 2.7 3 0 0 3 3 3 0 Spore wall protein Hid1 PF12722.7 GAM26783.1 - 8.6 4.3 17.9 9.5 4.2 17.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3837 PF12939.7 GAM26784.1 - 0.0081 16.5 0.0 0.018 15.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3837) KIAA1430 PF13879.6 GAM26785.1 - 0.35 11.6 5.7 1.1 10.1 5.7 1.7 1 0 0 1 1 1 0 KIAA1430 homologue E2F_TDP PF02319.20 GAM26786.1 - 1.4e-13 50.7 0.4 4.6e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain KAR9 PF08580.10 GAM26786.1 - 1.1 7.8 14.6 1.4 7.4 14.6 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 E2F_TDP PF02319.20 GAM26787.1 - 1.8e-22 79.1 0.0 1e-11 44.7 0.0 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 GAM26787.1 - 0.081 12.8 0.6 0.51 10.3 0.2 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Ribosomal_L31e PF01198.19 GAM26788.1 - 1.7e-35 121.1 0.2 2.5e-35 120.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e SdrD_B PF17210.3 GAM26789.1 - 4e-12 46.3 4.7 3e-06 27.4 0.3 2.2 1 1 1 2 2 2 2 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM26789.1 - 4.1e-07 30.2 0.3 0.00044 20.4 0.0 3.2 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain ApeC PF16977.5 GAM26789.1 - 5.2e-06 26.5 0.6 0.088 12.7 0.0 2.2 1 1 1 2 2 2 2 C-terminal domain of apextrin DUF2012 PF09430.10 GAM26789.1 - 0.0003 20.9 0.1 0.33 11.1 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 GAM26789.1 - 0.0018 18.2 1.5 0.65 10.0 0.0 3.5 2 1 2 4 4 4 1 CarboxypepD_reg-like domain CBM26 PF16738.5 GAM26789.1 - 0.017 15.4 0.6 1.3 9.3 0.0 3.0 2 1 1 3 3 3 0 Starch-binding module 26 DUF5123 PF17161.4 GAM26789.1 - 0.048 14.7 2.1 0.05 14.7 0.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5123) Cadherin-like PF12733.7 GAM26789.1 - 0.087 13.4 0.3 0.2 12.2 0.3 1.6 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain SpaA PF17802.1 GAM26789.1 - 0.098 13.0 0.5 17 5.8 0.0 2.5 1 1 0 2 2 2 0 Prealbumin-like fold domain Interfer-bind PF09294.10 GAM26789.1 - 0.32 11.3 1.5 1.8 8.9 0.3 2.7 2 1 2 4 4 4 0 Interferon-alpha/beta receptor, fibronectin type III SdrD_B PF17210.3 GAM26790.1 - 6.9e-19 68.1 14.4 8e-06 26.1 0.2 4.7 4 2 0 4 4 4 4 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM26790.1 - 5.5e-09 36.2 1.8 0.05 13.9 0.1 5.2 5 1 0 5 5 5 2 Carboxypeptidase regulatory-like domain SARA PF11409.8 GAM26790.1 - 0.00015 21.9 0.8 4.9 7.4 0.0 4.5 4 0 0 4 4 4 1 Smad anchor for receptor activation (SARA) SpaA PF17802.1 GAM26790.1 - 0.0071 16.7 1.4 14 6.1 0.0 3.9 3 1 0 3 3 3 1 Prealbumin-like fold domain phage_tail_N PF08400.10 GAM26790.1 - 0.0074 16.3 0.3 16 5.5 0.0 3.9 3 1 1 4 4 4 0 Prophage tail fibre N-terminal YoaP PF14268.6 GAM26790.1 - 0.045 13.3 5.0 18 5.0 0.1 4.1 4 0 0 4 4 4 0 YoaP-like MVL PF12151.8 GAM26790.1 - 0.057 13.3 0.0 19 5.2 0.0 3.4 3 0 0 3 3 3 0 Mannan-binding protein Chitin_bind_4 PF00379.23 GAM26790.1 - 0.089 13.3 1.6 6.5 7.4 0.0 2.9 3 0 0 3 3 2 0 Insect cuticle protein EF-hand_1 PF00036.32 GAM26790.1 - 0.12 12.0 0.7 7.6 6.3 0.1 2.8 2 0 0 2 2 2 0 EF hand DUF2141 PF09912.9 GAM26790.1 - 0.16 11.9 9.4 51 3.8 0.0 5.5 5 1 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2141) CarbopepD_reg_2 PF13715.6 GAM26790.1 - 0.17 11.9 0.7 63 3.7 0.0 4.4 5 1 0 5 5 5 0 CarboxypepD_reg-like domain SdrD_B PF17210.3 GAM26791.1 - 1.8e-15 57.1 18.4 2.4e-07 31.0 0.6 4.1 4 0 0 4 4 4 4 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM26791.1 - 6.2e-10 39.2 6.4 2.4e-06 27.7 0.2 3.9 4 1 0 4 4 4 2 Carboxypeptidase regulatory-like domain SpaA PF17802.1 GAM26791.1 - 0.00074 19.8 6.4 0.014 15.7 0.1 3.8 4 0 0 4 4 4 1 Prealbumin-like fold domain SdrD_B PF17210.3 GAM26792.1 - 0.0004 20.6 0.2 0.00099 19.3 0.0 1.7 2 0 0 2 2 2 1 SdrD B-like domain ApeC PF16977.5 GAM26792.1 - 0.0053 16.7 0.8 4 7.3 0.1 2.9 1 1 1 2 2 2 2 C-terminal domain of apextrin DUF2012 PF09430.10 GAM26792.1 - 0.0062 16.6 0.0 0.031 14.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 GAM26792.1 - 0.0085 16.4 0.1 0.018 15.3 0.0 1.6 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cys_Knot_tox PF17486.2 GAM26792.1 - 0.015 15.5 0.3 7.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Cystine knot toxins SpaA PF17802.1 GAM26792.1 - 0.032 14.5 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 Prealbumin-like fold domain Y_Y_Y PF07495.13 GAM26792.1 - 0.095 12.7 1.0 0.16 12.0 0.2 1.8 2 0 0 2 2 2 0 Y_Y_Y domain DRIM PF07539.12 GAM26794.1 - 3.5e-85 286.6 6.7 3.5e-85 286.6 6.7 5.0 4 1 0 4 4 4 1 Down-regulated in metastasis TMEM234 PF10639.9 GAM26794.1 - 1.1e-41 141.4 3.6 3.6e-41 139.9 3.6 2.0 1 0 0 1 1 1 1 Putative transmembrane family 234 HEAT PF02985.22 GAM26794.1 - 4.6e-05 23.3 0.2 17 6.0 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat EamA PF00892.20 GAM26794.1 - 0.0079 16.4 8.8 0.11 12.6 8.8 2.7 1 1 0 1 1 1 1 EamA-like transporter family Anti-adapt_IraP PF10796.9 GAM26794.1 - 0.035 14.6 5.2 0.13 12.9 0.8 4.0 4 0 0 4 4 4 0 Sigma-S stabilisation anti-adaptor protein TAF6_C PF07571.13 GAM26794.1 - 0.15 12.4 0.9 10 6.5 0.1 4.1 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain CH PF00307.31 GAM26795.1 - 3.1e-43 146.4 0.8 6.1e-22 77.9 0.0 3.7 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM26795.1 - 1.3e-11 44.2 0.0 1.2e-07 31.4 0.0 3.3 2 0 0 2 2 2 2 CAMSAP CH domain Spc7 PF08317.11 GAM26795.1 - 4.2e-05 22.6 25.9 4.2e-05 22.6 25.9 8.3 1 1 7 8 8 8 7 Spc7 kinetochore protein HMMR_N PF15905.5 GAM26795.1 - 0.00083 18.9 32.4 0.00083 18.9 32.4 7.9 1 1 7 8 8 8 3 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 GAM26795.1 - 0.0019 18.3 12.2 0.0019 18.3 12.2 10.0 2 1 4 6 6 6 2 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 GAM26795.1 - 0.0037 16.7 25.9 0.0037 16.7 25.9 7.5 1 1 7 8 8 8 2 Domain of unknown function (DUF4407) CH_2 PF06294.11 GAM26795.1 - 0.087 13.0 5.7 4.4 7.5 0.0 3.7 3 0 0 3 3 3 0 CH-like domain in sperm protein TIG PF01833.24 GAM26798.1 - 3e-11 43.2 32.7 2e-10 40.6 0.6 5.3 3 1 2 5 5 5 3 IPT/TIG domain Actin PF00022.19 GAM26799.1 - 5.8e-129 430.3 0.0 1.4e-128 429.0 0.0 1.6 1 1 0 1 1 1 1 Actin Ist1 PF03398.14 GAM26799.1 - 3.7e-44 150.6 0.4 5.7e-44 149.9 0.4 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Filamin PF00630.19 GAM26799.1 - 5.7e-39 133.1 3.1 1.3e-18 67.7 0.1 2.6 2 0 0 2 2 2 2 Filamin/ABP280 repeat Invasin_D3 PF09134.10 GAM26799.1 - 2.9e-08 33.9 3.1 0.0032 17.8 0.0 3.1 4 0 0 4 4 4 2 Invasin, domain 3 Neurexophilin PF06312.12 GAM26799.1 - 0.00016 21.2 1.6 0.22 10.9 0.1 2.3 2 0 0 2 2 2 2 Neurexophilin DUF2141 PF09912.9 GAM26799.1 - 0.0017 18.2 0.1 0.46 10.4 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2141) PPC PF04151.15 GAM26799.1 - 0.009 17.1 3.4 3.7 8.7 0.1 2.6 2 0 0 2 2 2 2 Bacterial pre-peptidase C-terminal domain DUF5011 PF16403.5 GAM26799.1 - 0.03 14.5 0.5 0.099 12.8 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) Cadherin_5 PF17892.1 GAM26799.1 - 0.042 13.8 2.0 0.78 9.8 0.1 3.0 3 0 0 3 3 3 0 Cadherin-like domain He_PIG PF05345.12 GAM26799.1 - 0.92 9.8 3.9 20 5.5 0.4 3.0 3 0 0 3 3 3 0 Putative Ig domain Coiled PF05710.12 GAM26800.1 - 0.019 15.8 8.1 0.028 15.2 8.0 1.5 1 1 0 1 1 1 0 Coiled coil GEMIN8 PF15348.6 GAM26801.1 - 0.00052 20.4 11.8 0.00057 20.3 11.8 1.1 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 NOA36 PF06524.12 GAM26801.1 - 0.018 14.4 3.7 0.028 13.7 3.7 1.4 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GAM26801.1 - 0.48 10.1 4.3 0.76 9.4 4.3 1.4 1 0 0 1 1 1 0 FAM176 family Glucosamine_iso PF01182.20 GAM26802.1 - 3.4e-19 69.6 0.0 4.3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase baeRF_family7 PF18849.1 GAM26802.1 - 0.058 13.6 0.0 3.7 7.8 0.0 2.4 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 TPR_17 PF13431.6 GAM26803.1 - 9.1e-54 176.1 31.1 4.7e-08 32.9 0.1 9.1 8 1 0 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.6 GAM26803.1 - 4.6e-29 99.8 47.8 6.5e-05 22.5 0.5 8.9 8 1 1 9 9 9 8 TPR repeat TPR_14 PF13428.6 GAM26803.1 - 5.7e-06 26.7 9.5 39 5.4 0.0 7.5 7 1 0 7 7 7 0 Tetratricopeptide repeat Ste5 PF11610.8 GAM26803.1 - 0.0025 17.6 0.1 7.9 6.5 0.0 5.4 7 0 0 7 7 7 1 Scaffold protein Ste5, Fus3-binding region TPR_8 PF13181.6 GAM26803.1 - 0.017 15.3 24.4 39 4.8 0.0 10.4 12 0 0 12 12 12 0 Tetratricopeptide repeat DUF1155 PF06633.11 GAM26803.1 - 2.7 7.5 22.1 7.3 6.2 0.2 6.4 7 0 0 7 7 7 0 Protein of unknown function (DUF1155) PK PF00224.21 GAM26804.1 - 9.7e-124 412.7 5.0 1.5e-123 412.1 5.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAM26804.1 - 1.5e-29 102.6 0.1 4.2e-29 101.2 0.1 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAM26804.1 - 0.00011 21.5 0.2 0.00019 20.7 0.2 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Imm39 PF15568.6 GAM26804.1 - 0.03 14.4 0.1 0.06 13.5 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 39 ABC_tran PF00005.27 GAM26805.1 - 3.1e-16 60.1 0.3 0.00023 21.7 0.0 4.3 4 0 0 4 4 4 4 ABC transporter SMC_N PF02463.19 GAM26805.1 - 1.1e-08 34.8 0.0 0.33 10.3 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAM26805.1 - 4.5e-07 30.4 0.1 0.078 13.4 0.0 3.3 3 1 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 GAM26805.1 - 2.2e-06 27.3 3.6 0.037 13.8 0.2 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAM26805.1 - 1.8e-05 25.0 1.0 0.86 9.9 0.0 3.8 3 1 1 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 GAM26805.1 - 6.4e-05 22.9 0.3 0.28 11.1 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase AAA_21 PF13304.6 GAM26805.1 - 8.5e-05 22.5 11.9 0.011 15.5 0.1 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAM26805.1 - 0.00035 20.2 0.1 0.27 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain DnaJ_CXXCXGXG PF00684.19 GAM26805.1 - 0.0011 19.3 1.2 0.039 14.3 0.3 2.6 2 0 0 2 2 2 1 DnaJ central domain ATPase PF06745.13 GAM26805.1 - 0.0025 17.2 0.0 0.29 10.5 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 GAM26805.1 - 0.0069 15.9 0.0 0.89 9.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 GAM26805.1 - 0.0085 15.8 0.6 4.9 6.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAM26805.1 - 0.009 16.6 0.1 1.8 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 GAM26805.1 - 0.016 15.1 0.8 10 6.0 0.0 3.0 2 1 1 3 3 3 0 Adenylylsulphate kinase PRK PF00485.18 GAM26805.1 - 0.026 14.3 0.1 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.18 GAM26805.1 - 0.031 14.0 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 GAM26805.1 - 0.049 13.8 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM26805.1 - 0.077 13.4 0.1 20 5.7 0.0 3.0 3 0 0 3 3 3 0 RNA helicase NACHT PF05729.12 GAM26805.1 - 0.089 12.7 0.0 6.9 6.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 GAM26805.1 - 0.091 12.5 0.3 32 4.1 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain CobU PF02283.16 GAM26805.1 - 0.1 12.2 0.2 0.63 9.6 0.0 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase T2SSE PF00437.20 GAM26805.1 - 0.1 11.7 0.3 2 7.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 GAM26805.1 - 0.11 12.4 0.1 7 6.5 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 GAM26805.1 - 0.2 11.4 0.1 26 4.5 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase BCA_ABC_TP_C PF12399.8 GAM26805.1 - 0.28 11.2 0.1 0.28 11.2 0.1 1.9 2 0 0 2 2 1 0 Branched-chain amino acid ATP-binding cassette transporter Zn-ribbon_8 PF09723.10 GAM26805.1 - 0.28 11.3 1.8 24 5.1 0.0 2.9 3 0 0 3 3 3 0 Zinc ribbon domain IIGP PF05049.13 GAM26805.1 - 0.33 10.0 1.0 2.9 6.9 0.2 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Lar_restr_allev PF14354.6 GAM26805.1 - 0.52 10.7 3.0 0.23 11.9 0.3 1.8 2 0 0 2 2 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 GAM26805.1 - 1.3 9.0 7.4 17 5.5 0.2 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-IS66 PF13005.7 GAM26805.1 - 2.3 8.7 6.9 4.5 7.7 0.2 3.3 2 1 1 3 3 3 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_9 PF14369.6 GAM26805.1 - 4.4 7.6 8.8 44 4.4 0.1 3.3 2 1 1 3 3 3 0 zinc-ribbon zf-ribbon_3 PF13248.6 GAM26805.1 - 7.5 6.1 9.3 16 5.0 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain ABC_tran PF00005.27 GAM26806.1 - 8.6e-15 55.5 0.0 1.7e-08 35.1 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAM26806.1 - 3.2e-07 30.5 0.5 0.017 14.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 GAM26806.1 - 1.5e-05 24.8 0.1 0.095 12.7 0.0 2.5 2 0 0 2 2 2 2 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 GAM26806.1 - 1.9e-05 24.2 0.0 0.0085 15.5 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAM26806.1 - 0.00031 20.6 1.2 4 7.1 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 GAM26806.1 - 0.0021 18.0 0.0 0.01 15.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 GAM26806.1 - 0.0022 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DnaJ_CXXCXGXG PF00684.19 GAM26806.1 - 0.0028 18.0 0.6 0.25 11.7 0.2 3.0 3 0 0 3 3 3 1 DnaJ central domain AAA_16 PF13191.6 GAM26806.1 - 0.0099 16.3 0.0 0.025 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAM26806.1 - 0.013 15.8 0.0 0.041 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 GAM26806.1 - 0.049 13.4 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UvrA_DNA-bind PF17755.1 GAM26806.1 - 0.064 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 UvrA DNA-binding domain AAA_18 PF13238.6 GAM26806.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM26806.1 - 0.17 12.1 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GAM26806.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 GAM26806.1 - 0.2 11.7 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 GAM26806.1 - 0.22 10.9 1.2 0.42 10.0 0.0 1.9 3 0 0 3 3 3 0 Poxvirus A32 protein Sugar_tr PF00083.24 GAM26807.1 - 0.03 13.2 0.2 0.03 13.2 0.2 1.7 2 0 0 2 2 2 0 Sugar (and other) transporter tRNA-synt_1b PF00579.25 GAM26808.1 - 2.2e-41 142.1 0.0 2.6e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1 PF00133.22 GAM26809.1 - 4.7e-192 639.4 2.1 1.5e-190 634.5 2.1 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM26809.1 - 9.7e-37 126.3 0.0 1.7e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM26809.1 - 1e-21 77.2 7.7 2.3e-08 33.2 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAM26809.1 - 2.2e-10 40.4 0.2 1.6e-06 27.8 0.1 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 GAM26809.1 - 8.6e-07 29.1 1.6 2.3e-06 27.8 1.6 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 GAM26809.1 - 6.4e-06 25.7 0.0 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 GAM26809.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF4116 PF13475.6 GAM26810.1 - 1.8e-213 690.3 35.7 1.9e-18 65.9 0.1 15.6 8 4 7 17 17 17 17 Domain of unknown function (DUF4116) DUF1667 PF07892.11 GAM26810.1 - 1.8e-08 34.3 0.0 20 5.3 0.0 9.5 9 2 2 11 11 11 0 Protein of unknown function (DUF1667) Spc110_C PF18520.1 GAM26810.1 - 0.00025 20.6 0.0 19 5.0 0.0 7.0 9 0 0 9 9 9 1 Spindle pole body component 110 C-terminal domain mTERF PF02536.14 GAM26810.1 - 0.083 11.8 0.3 44 2.9 0.0 4.8 4 1 1 6 6 6 0 mTERF DUF1924 PF09086.11 GAM26810.1 - 0.28 11.6 1.5 1.6e+02 2.7 0.0 4.8 4 1 1 5 5 5 0 Domain of unknown function (DUF1924) DUF3201 PF11447.8 GAM26810.1 - 0.37 10.3 3.5 17 4.9 0.0 3.9 4 2 0 4 4 4 0 Protein of unknown function (DUF3201) DFP PF04127.15 GAM26810.1 - 0.89 9.4 15.7 2.5 7.9 0.2 4.2 2 1 2 4 4 4 0 DNA / pantothenate metabolism flavoprotein IL6 PF00489.17 GAM26810.1 - 1.8 8.1 25.0 3.6 7.1 0.2 6.8 1 1 3 7 7 7 0 Interleukin-6/G-CSF/MGF family DUF2971 PF11185.8 GAM26810.1 - 6.4 8.0 9.1 15 6.8 0.2 4.9 3 2 1 4 4 4 0 Protein of unknown function (DUF2971) ATP-synt_ab PF00006.25 GAM26811.1 - 8.4e-44 149.8 0.0 1.2e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAM26811.1 - 2.6e-07 31.0 0.1 5.8e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 GAM26812.1 - 5.1e-77 258.3 0.0 6.9e-77 257.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 GAM26812.1 - 4.7e-31 107.2 0.0 1e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 GAM26812.1 - 1e-09 38.7 1.3 2.7e-09 37.4 1.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ProQ_C PF17516.2 GAM26812.1 - 0.042 13.3 0.2 0.091 12.2 0.2 1.5 1 0 0 1 1 1 0 ProQ C-terminal domain Glyco_hydro_16 PF00722.21 GAM26812.1 - 0.066 12.7 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 Bac_surface_Ag PF01103.23 GAM26814.1 - 6.2e-26 91.7 2.2 6.9e-26 91.5 2.2 1.0 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 GAM26814.1 - 0.025 14.0 0.4 0.08 12.4 0.4 1.8 1 1 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Usher_TcfC PF17271.2 GAM26814.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 TcfC Usher-like barrel domain OmpH PF03938.14 GAM26815.1 - 5.7e-24 85.0 2.8 6.7e-24 84.8 2.8 1.0 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DNA_gyraseB PF00204.25 GAM26815.1 - 0.0083 15.6 0.1 0.021 14.3 0.0 1.6 2 0 0 2 2 2 1 DNA gyrase B AvrM-A PF18241.1 GAM26815.1 - 0.01 16.2 1.3 0.076 13.4 1.3 2.1 1 1 0 1 1 1 0 Flax-rust effector AvrM-A Nup88 PF10168.9 GAM26815.1 - 0.015 13.2 0.7 0.016 13.0 0.7 1.1 1 0 0 1 1 1 0 Nuclear pore component OrfB_IS605 PF01385.19 GAM26815.1 - 0.017 15.3 0.2 0.05 13.8 0.2 1.8 1 1 0 1 1 1 0 Probable transposase Apolipoprotein PF01442.18 GAM26815.1 - 0.023 14.6 1.9 0.038 13.8 1.9 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ATP-grasp_4 PF13535.6 GAM26815.1 - 0.027 14.1 0.8 0.082 12.5 0.1 1.9 2 0 0 2 2 2 0 ATP-grasp domain ATP-synt_B PF00430.18 GAM26815.1 - 0.03 14.4 1.3 0.047 13.8 1.3 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Mer2 PF09074.10 GAM26815.1 - 0.031 14.1 2.6 0.037 13.8 2.6 1.3 1 1 0 1 1 1 0 Mer2 UPF0242 PF06785.11 GAM26815.1 - 0.034 14.2 3.3 0.045 13.8 3.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fzo_mitofusin PF04799.13 GAM26815.1 - 0.042 13.4 1.0 0.084 12.4 1.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region Methyltransf_30 PF05430.11 GAM26815.1 - 0.063 13.2 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase FlxA PF14282.6 GAM26815.1 - 0.48 10.4 7.1 0.92 9.5 7.1 1.5 1 1 0 1 1 1 0 FlxA-like protein DUF5344 PF17279.2 GAM26815.1 - 1.5 9.4 6.9 16 6.2 3.9 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5344) tRNA-synt_2 PF00152.20 GAM26817.1 - 9.9e-78 261.4 0.0 1.1e-77 261.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 GAM26817.1 - 3.5e-07 30.0 0.9 0.001 18.6 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) LEM PF03020.15 GAM26817.1 - 0.002 17.6 2.1 0.19 11.3 0.2 3.3 3 0 0 3 3 3 1 LEM domain tRNA_anti-codon PF01336.25 GAM26817.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain 2-oxoacid_dh PF00198.23 GAM26818.1 - 4.9e-85 284.7 0.1 6.5e-85 284.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 GAM26818.1 - 1.7e-14 53.8 0.1 5.1e-14 52.3 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 GAM26818.1 - 4.3e-14 52.1 0.7 1.1e-13 50.8 0.3 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAM26818.1 - 0.00082 19.2 0.0 0.0024 17.7 0.0 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_3 PF13437.6 GAM26818.1 - 0.028 15.1 0.1 0.064 14.0 0.1 1.6 1 0 0 1 1 1 0 HlyD family secretion protein Transket_pyr PF02779.24 GAM26819.1 - 5.1e-47 159.8 0.0 7.4e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAM26819.1 - 4.4e-39 133.2 0.1 9e-39 132.2 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Peptidase_M20 PF01546.28 GAM26819.1 - 0.0068 16.1 0.0 0.0087 15.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PFOR_II PF17147.4 GAM26819.1 - 0.015 15.6 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II FMN_red PF03358.15 GAM26819.1 - 0.028 14.2 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 NADPH-dependent FMN reductase HGTP_anticodon PF03129.20 GAM26819.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Anticodon binding domain E1_dh PF00676.20 GAM26820.1 - 1.3e-71 241.0 0.0 1.5e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 GAM26820.1 - 2.7e-06 27.3 0.2 1.1e-05 25.3 0.2 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 GAM26820.1 - 0.00023 20.5 0.0 0.0031 16.8 0.0 2.4 3 0 0 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase COX1 PF00115.20 GAM26821.1 - 8.6e-141 469.7 72.4 8.6e-141 469.7 72.4 1.9 2 0 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I Pyr_redox_2 PF07992.14 GAM26822.1 - 5.9e-48 163.6 0.3 6.6e-48 163.4 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM26822.1 - 3.2e-21 75.9 0.4 6.2e-19 68.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM26822.1 - 8.5e-19 67.9 0.4 6.5e-17 61.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM26822.1 - 0.0012 18.3 0.2 0.031 13.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 GAM26822.1 - 0.0015 18.9 0.1 0.014 15.8 0.0 2.4 2 2 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 GAM26822.1 - 0.0026 16.9 3.9 0.045 12.8 0.0 3.6 4 1 1 5 5 5 1 FAD binding domain HI0933_like PF03486.14 GAM26822.1 - 0.0099 14.6 0.1 2.2 6.9 0.0 2.7 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 GAM26822.1 - 0.037 14.3 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM26822.1 - 0.041 13.5 1.9 1.4 8.4 0.1 3.2 2 1 1 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 GAM26822.1 - 0.063 12.4 4.6 1.1 8.3 0.0 3.9 3 1 2 5 5 5 0 Glucose inhibited division protein A ABC_tran PF00005.27 GAM26823.1 - 9.4e-35 120.1 0.0 1.3e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAM26823.1 - 1.3e-10 41.5 2.3 3.1e-05 23.9 0.3 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAM26823.1 - 8.7e-05 23.0 0.4 0.0003 21.2 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 GAM26823.1 - 0.00011 21.7 0.3 0.0015 18.0 0.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAM26823.1 - 0.00025 21.3 1.2 0.0023 18.2 1.2 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 GAM26823.1 - 0.0013 19.1 0.4 0.0064 16.9 0.4 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM26823.1 - 0.0018 18.3 0.0 0.0048 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 GAM26823.1 - 0.0039 17.1 0.1 0.0075 16.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 GAM26823.1 - 0.0066 15.3 0.4 0.086 11.6 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 GAM26823.1 - 0.0072 15.9 0.0 0.018 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAM26823.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM26823.1 - 0.017 15.6 0.0 0.042 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAM26823.1 - 0.032 14.1 0.1 0.072 13.0 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 GAM26823.1 - 0.033 14.1 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 GAM26823.1 - 0.034 14.4 0.0 0.09 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 GAM26823.1 - 0.036 13.5 0.4 6.3 6.2 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DLIC PF05783.11 GAM26823.1 - 0.039 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Rad17 PF03215.15 GAM26823.1 - 0.06 13.3 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 GAM26823.1 - 0.061 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM26823.1 - 0.066 13.7 1.3 0.066 13.7 1.3 1.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 GAM26823.1 - 0.07 12.8 0.3 1.1 8.9 0.1 2.0 1 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 GAM26823.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.14 GAM26825.1 - 2.4e-45 155.0 0.1 4.1e-45 154.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 GAM26825.1 - 5.1e-23 81.9 6.3 1e-13 51.7 0.0 4.1 3 1 1 4 4 4 2 Apoptosis-inducing factor, mitochondrion-associated, C-term NAD_binding_9 PF13454.6 GAM26825.1 - 8.4e-09 35.6 0.9 0.0033 17.4 0.1 4.1 3 1 1 4 4 4 3 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAM26825.1 - 3.1e-07 30.8 2.9 9.2e-07 29.3 0.0 3.0 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM26825.1 - 3e-06 26.7 0.5 0.00021 20.6 0.2 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAM26825.1 - 4e-05 23.1 0.7 0.0001 21.8 0.3 1.7 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 GAM26825.1 - 0.00062 19.0 2.0 0.17 11.0 0.0 3.1 3 1 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 GAM26825.1 - 0.0011 19.3 0.0 0.01 16.3 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 GAM26825.1 - 0.0035 16.1 0.6 0.064 11.9 0.1 2.9 3 1 1 4 4 4 1 HI0933-like protein DAO PF01266.24 GAM26825.1 - 3.6 7.1 7.9 0.45 10.0 0.0 2.9 4 0 0 4 4 4 0 FAD dependent oxidoreductase Methyltransf_11 PF08241.12 GAM26826.1 - 4.2e-20 72.2 0.0 1.2e-19 70.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM26826.1 - 5.6e-20 71.7 0.0 9.5e-20 70.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM26826.1 - 1.5e-19 70.5 0.0 3.2e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM26826.1 - 3.2e-15 56.1 0.0 4.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAM26826.1 - 9.2e-14 51.6 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM26826.1 - 4.4e-11 43.4 0.1 1.3e-10 41.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 GAM26826.1 - 4.1e-06 26.7 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 GAM26826.1 - 1.3e-05 24.9 0.0 2.8e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Pox_MCEL PF03291.16 GAM26826.1 - 2e-05 23.9 0.1 3.8e-05 22.9 0.1 1.5 2 0 0 2 2 2 1 mRNA capping enzyme CMAS PF02353.20 GAM26826.1 - 0.00033 20.0 0.0 0.00056 19.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 GAM26826.1 - 0.011 15.3 0.0 0.042 13.3 0.0 2.0 1 1 0 1 1 1 0 Putative methyltransferase TehB PF03848.14 GAM26826.1 - 0.027 13.9 0.1 0.05 13.0 0.1 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 GAM26826.1 - 0.041 12.8 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.14 GAM26826.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Vezatin PF12632.7 GAM26827.1 - 0.068 12.6 0.8 0.15 11.4 0.8 1.5 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Zn_peptidase_2 PF04298.12 GAM26827.1 - 5.8 6.3 10.9 1.2 8.5 2.4 2.4 2 1 0 2 2 2 0 Putative neutral zinc metallopeptidase Ras PF00071.22 GAM26829.1 - 2.4e-56 189.8 0.1 2.8e-56 189.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM26829.1 - 1e-33 116.1 0.1 2e-33 115.1 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM26829.1 - 5.4e-13 48.8 0.1 6.1e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM26829.1 - 0.0027 17.1 0.1 0.0042 16.5 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAM26829.1 - 0.0063 16.4 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 GAM26829.1 - 0.015 14.9 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM26829.1 - 0.068 13.2 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 GAM26829.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase Cyt-b5 PF00173.28 GAM26830.1 - 5e-22 77.8 0.1 6.4e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AIG1 PF04548.16 GAM26831.1 - 6.4e-22 77.9 0.0 9.9e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GAM26831.1 - 1.2e-10 41.5 0.0 2.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM26831.1 - 2.9e-05 24.0 0.1 5.3e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 GAM26831.1 - 0.00024 21.2 2.9 0.02 14.9 0.1 2.7 2 1 1 3 3 3 2 Dynamin family Septin PF00735.18 GAM26831.1 - 0.0013 18.1 0.3 0.0043 16.4 0.3 1.8 1 1 0 1 1 1 1 Septin AAA_16 PF13191.6 GAM26831.1 - 0.0016 18.9 0.0 0.0037 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 GAM26831.1 - 0.007 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 GAM26831.1 - 0.012 15.0 0.2 0.12 11.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 GAM26831.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 GAM26831.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.13 GAM26831.1 - 0.024 13.8 0.0 0.065 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 GAM26831.1 - 0.033 14.7 0.2 0.088 13.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 GAM26831.1 - 0.058 12.7 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sigma54_activat PF00158.26 GAM26831.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TniB PF05621.11 GAM26831.1 - 0.16 11.4 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein Tmemb_185A PF10269.9 GAM26832.1 - 3.5e-37 128.4 18.4 3.5e-37 128.4 18.4 1.6 2 0 0 2 2 2 1 Transmembrane Fragile-X-F protein DnaJ PF00226.31 GAM26832.1 - 1.3e-25 89.3 2.1 2.5e-25 88.4 2.1 1.5 1 0 0 1 1 1 1 DnaJ domain EVE PF01878.18 GAM26833.1 - 5.9e-10 39.3 0.0 9.1e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 EVE domain N-Term_TEN PF11474.8 GAM26833.1 - 0.018 14.7 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain Transket_pyr PF02779.24 GAM26834.1 - 1.6e-47 161.5 0.0 2.5e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAM26834.1 - 3.2e-36 124.0 0.0 5.4e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain Myb_DNA-binding PF00249.31 GAM26835.1 - 0.00031 20.9 1.8 0.00037 20.6 0.6 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM26835.1 - 0.016 15.4 0.2 0.016 15.4 0.2 2.5 4 0 0 4 4 4 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 GAM26835.1 - 0.1 12.9 0.2 0.1 12.9 0.2 2.3 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Chi-conotoxin PF16981.5 GAM26835.1 - 0.53 10.6 1.5 9.7 6.5 0.1 2.8 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily TPR_2 PF07719.17 GAM26836.1 - 3.8e-12 45.3 7.1 0.0065 16.5 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM26836.1 - 1.4e-11 43.6 9.8 0.09 13.0 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAM26836.1 - 1.2e-10 41.7 0.2 0.014 15.9 0.1 3.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAM26836.1 - 3.3e-10 39.9 0.0 0.029 15.2 0.0 4.4 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM26836.1 - 9.7e-08 32.2 1.0 0.084 13.2 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM26836.1 - 1.7e-07 31.1 0.4 0.51 10.8 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM26836.1 - 6.8e-06 25.7 14.1 0.014 15.2 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAM26836.1 - 6.9e-06 26.6 0.0 0.02 15.5 0.0 2.9 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM26836.1 - 7.9e-06 25.6 0.0 0.74 10.0 0.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAM26836.1 - 1e-05 25.2 1.4 1 9.3 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat SNAP PF14938.6 GAM26836.1 - 5.3e-05 22.8 3.1 9e-05 22.0 0.1 2.4 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 GAM26836.1 - 0.00045 20.4 1.5 0.74 10.1 0.9 3.1 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.9 GAM26836.1 - 0.00075 19.3 0.1 0.0014 18.4 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) Mad3_BUB1_I PF08311.12 GAM26836.1 - 0.00084 19.3 1.7 0.0037 17.2 0.1 2.7 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 GAM26836.1 - 0.0012 18.1 0.5 0.042 13.0 0.1 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM26836.1 - 0.0023 18.5 0.6 14 6.6 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAM26836.1 - 0.0029 17.7 0.1 0.078 13.1 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 GAM26836.1 - 0.0032 16.5 0.1 0.022 13.8 0.0 1.9 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.23 GAM26836.1 - 0.0099 15.1 2.7 2.4 7.3 0.1 2.9 2 1 1 3 3 3 2 FAT domain TPR_20 PF14561.6 GAM26836.1 - 0.014 15.8 0.0 0.24 11.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.12 GAM26836.1 - 0.059 14.1 6.2 0.093 13.4 0.9 3.0 3 0 0 3 3 2 0 Sel1 repeat RNA_pol_I_TF PF04090.12 GAM26836.1 - 0.067 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor TPR_11 PF13414.6 GAM26836.1 - 0.27 10.9 6.7 0.61 9.8 0.0 3.8 4 0 0 4 4 4 0 TPR repeat Trnau1ap PF17654.1 GAM26837.1 - 0.026 15.4 0.1 0.055 14.3 0.1 1.5 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins DUF3485 PF11984.8 GAM26837.1 - 0.06 13.1 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3485) STT3 PF02516.14 GAM26838.1 - 2.2e-131 439.1 41.8 2e-130 436.0 41.8 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit GATA PF00320.27 GAM26839.1 - 1.8e-16 59.4 5.6 3.4e-16 58.6 5.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Pirin PF02678.16 GAM26840.1 - 9.7e-36 122.0 0.1 1.9e-35 121.1 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 GAM26840.1 - 6.2e-29 100.4 0.0 3.8e-28 97.9 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain UCH PF00443.29 GAM26841.1 - 2.5e-44 151.7 3.5 2.5e-44 151.7 3.5 4.2 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM26841.1 - 3e-30 105.9 2.3 3e-30 105.9 2.3 3.6 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 GAM26841.1 - 5.8e-05 22.8 0.6 0.00031 20.4 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin family TTRAP PF14203.6 GAM26841.1 - 0.0038 17.2 0.6 0.027 14.5 0.6 2.5 1 0 0 1 1 1 1 Putative tranposon-transfer assisting protein GlutR_dimer PF00745.20 GAM26841.1 - 0.13 12.8 0.3 1.4 9.4 0.3 3.0 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Ubiquitin_5 PF18037.1 GAM26841.1 - 0.31 11.4 2.6 0.37 11.2 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain YjgF_endoribonc PF14588.6 GAM26842.1 - 8.4e-26 90.9 0.0 9.4e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 GAM26842.1 - 6.3e-16 58.5 0.1 8.6e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP CDC73_C PF05179.14 GAM26843.1 - 6.8e-43 146.1 1.5 6.8e-43 146.1 1.5 2.2 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 GAM26843.1 - 1.6e-23 83.5 5.0 2.4e-23 82.9 5.0 1.3 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal Zip PF02535.22 GAM26843.1 - 0.69 9.1 4.1 0.95 8.6 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EPL1 PF10513.9 GAM26843.1 - 1.3 9.4 15.2 0.16 12.3 7.1 2.4 2 1 0 2 2 2 0 Enhancer of polycomb-like ANAPC_CDC26 PF10471.9 GAM26843.1 - 1.4 9.8 13.7 7 7.6 13.7 2.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 CLN3 PF02487.17 GAM26843.1 - 4.3 6.3 5.2 4.6 6.2 3.6 1.7 2 0 0 2 2 2 0 CLN3 protein Presenilin PF01080.17 GAM26843.1 - 6.2 5.5 8.8 8.1 5.1 8.8 1.3 1 0 0 1 1 1 0 Presenilin Ecm29 PF13001.7 GAM26844.1 - 3.3e-127 425.2 5.9 3.3e-127 425.2 5.9 4.4 4 2 0 5 5 5 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 GAM26844.1 - 9.6e-08 32.5 0.2 0.029 14.9 0.0 7.2 5 2 1 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAM26844.1 - 9.3e-07 28.6 0.2 56 4.4 0.0 8.5 10 0 0 10 10 10 0 HEAT repeat Cnd1 PF12717.7 GAM26844.1 - 0.00084 19.4 20.0 2.1 8.3 0.0 7.7 7 1 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 DUF167 PF02594.16 GAM26844.1 - 0.041 14.0 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 TAF6_C PF07571.13 GAM26844.1 - 0.11 12.9 0.1 7.2 7.0 0.0 4.0 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain SE PF08491.10 GAM26845.1 - 1.1e-96 323.1 0.0 1.4e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 GAM26845.1 - 5.2e-16 58.8 0.0 4.9e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAM26845.1 - 0.0017 17.6 0.3 0.0026 17.0 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 GAM26845.1 - 0.0047 15.5 0.0 0.012 14.1 0.0 1.6 2 0 0 2 2 2 1 GDP dissociation inhibitor Lycopene_cycl PF05834.12 GAM26845.1 - 0.011 14.9 0.8 0.55 9.2 0.5 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 GAM26845.1 - 0.028 14.0 0.5 0.26 10.8 0.8 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM26845.1 - 0.074 12.1 2.5 0.11 11.6 2.5 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 GAM26845.1 - 0.074 13.3 1.1 0.16 12.3 1.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Reprolysin_3 PF13582.6 GAM26845.1 - 0.12 12.9 0.1 0.23 12.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Thi4 PF01946.17 GAM26845.1 - 0.17 11.1 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ChAPs PF09295.10 GAM26846.1 - 1.9e-45 155.6 0.6 5.2e-45 154.1 0.6 1.7 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 GAM26846.1 - 7.6e-06 26.3 0.3 0.021 15.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 GAM26846.1 - 0.0059 15.6 2.8 0.086 11.7 0.1 2.6 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 GAM26846.1 - 0.0071 16.4 0.1 20 5.6 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Tim29 PF10171.9 GAM26846.1 - 0.023 14.2 0.1 0.052 13.0 0.1 1.6 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 TPR_14 PF13428.6 GAM26846.1 - 0.023 15.5 0.4 85 4.4 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAM26846.1 - 0.16 12.2 0.9 4.9 7.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM26846.1 - 8.7 6.7 5.7 28 5.0 0.1 4.0 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 VCBS PF13517.6 GAM26847.1 - 3.2e-22 78.9 26.8 5.8e-06 26.8 0.5 7.6 5 2 2 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAM26847.1 - 8.3e-13 48.2 15.3 0.062 13.4 0.1 6.3 6 0 0 6 6 6 5 FG-GAP repeat Itfg2 PF15907.5 GAM26847.1 - 4.8e-07 29.1 4.6 0.12 11.4 0.1 6.1 6 1 1 7 7 7 3 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 GAM26847.1 - 0.00037 20.5 2.0 1.4 9.0 0.1 5.0 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 GAM26847.1 - 0.018 15.0 0.1 5.6 6.9 0.1 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal BBS2_C PF14782.6 GAM26847.1 - 0.32 9.7 0.4 2.8 6.6 0.1 2.5 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, C-terminal HEAT PF02985.22 GAM26848.1 - 6.7e-16 57.0 8.0 0.088 13.1 0.1 8.0 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.6 GAM26848.1 - 7.9e-07 29.4 1.3 2.3 8.7 0.0 7.0 7 1 1 8 8 8 1 HEAT repeats HEAT_EZ PF13513.6 GAM26848.1 - 1.8e-05 25.1 0.9 3.3 8.3 0.0 6.3 5 1 1 6 6 6 1 HEAT-like repeat Cnd1 PF12717.7 GAM26848.1 - 7.6e-05 22.8 9.6 0.29 11.2 0.6 6.0 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GAM26848.1 - 0.0074 16.9 0.4 1.8 9.2 0.1 4.1 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 GAM26848.1 - 0.0096 15.5 2.7 5.8 6.4 0.0 4.3 4 1 0 4 4 4 2 CLASP N terminal B56 PF01603.20 GAM26848.1 - 0.012 14.6 0.1 2.2 7.2 0.0 3.1 3 0 0 3 3 3 0 Protein phosphatase 2A regulatory B subunit (B56 family) RTP1_C1 PF10363.9 GAM26848.1 - 0.015 15.5 3.0 23 5.2 0.0 4.9 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 GAM26848.1 - 0.11 12.8 1.3 36 4.8 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Pneumovirus_M2 PF06436.11 GAM26848.1 - 0.16 11.5 0.7 0.65 9.5 0.1 2.2 2 0 0 2 2 2 0 Pneumovirus matrix protein 2 (M2) MVP_shoulder PF11978.8 GAM26849.1 - 3.8e-46 156.0 0.0 6.8e-46 155.1 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 GAM26849.1 - 1.7e-31 108.1 0.1 2.6e-29 101.0 0.0 2.5 2 0 0 2 2 2 1 Major Vault Protein Repeat domain Vault PF01505.18 GAM26849.1 - 1.2e-27 95.8 0.0 2.9e-15 56.2 0.0 2.8 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_4 PF17796.1 GAM26849.1 - 3.1e-22 78.4 0.0 2.3e-21 75.6 0.0 2.3 2 0 0 2 2 2 1 Major Vault Protein repeat domain Vault_2 PF17794.1 GAM26849.1 - 3.6e-10 40.1 0.0 7.7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Major Vault Protein repeat domain Ribosomal_L16 PF00252.18 GAM26850.1 - 1.9e-41 141.1 0.0 2.8e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e FSH1 PF03959.13 GAM26851.1 - 6.1e-45 153.5 0.0 1.4e-44 152.3 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF924 PF06041.11 GAM26851.1 - 2.1e-44 151.8 5.0 2.1e-44 151.8 2.6 2.2 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF924) LRR_6 PF13516.6 GAM26851.1 - 2.9e-12 45.6 22.7 5.8e-05 22.8 0.1 9.0 9 0 0 9 9 9 3 Leucine Rich repeat SpoU_sub_bind PF08032.12 GAM26851.1 - 0.017 15.4 1.0 62 4.0 0.0 4.7 6 0 0 6 6 6 0 RNA 2'-O ribose methyltransferase substrate binding DLH PF01738.18 GAM26851.1 - 0.074 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Pribosyltran PF00156.27 GAM26852.1 - 4e-26 91.4 0.4 3.6e-25 88.3 0.4 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAM26852.1 - 1.5e-06 27.9 0.1 3.9e-06 26.4 0.1 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 GAM26852.1 - 7.3e-05 22.4 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase Peptidase_S64 PF08192.11 GAM26853.1 - 0.0019 16.8 0.3 0.0058 15.2 0.0 1.8 1 1 1 2 2 2 1 Peptidase family S64 RasGEF_N_2 PF14663.6 GAM26853.1 - 0.03 14.7 1.1 11 6.5 0.1 2.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DASH_Duo1 PF08651.10 GAM26853.1 - 0.12 12.2 3.1 0.78 9.6 0.1 3.1 2 0 0 2 2 2 0 DASH complex subunit Duo1 Mucin PF01456.17 GAM26853.1 - 1.1 9.2 44.4 0.49 10.4 34.1 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Bud13 PF09736.9 GAM26853.1 - 3.7 7.9 9.2 7.6 6.9 9.2 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Prominin PF05478.11 GAM26853.1 - 7.9 4.3 9.2 0.15 10.0 0.9 2.0 2 0 0 2 2 2 0 Prominin LMWPc PF01451.21 GAM26854.1 - 2.3e-19 70.2 0.0 4.5e-19 69.2 0.0 1.4 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase AAA_lid_2 PF17863.1 GAM26855.1 - 1.2e-10 41.1 0.0 2.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 GAM26855.1 - 8.1e-06 25.7 0.4 2e-05 24.5 0.4 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DAG_kinase_N PF14513.6 GAM26855.1 - 0.43 10.8 8.9 0.093 12.9 0.8 2.9 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus SGS PF05002.15 GAM26856.1 - 2.2e-24 85.4 1.1 2.2e-24 85.4 1.1 2.2 2 0 0 2 2 1 1 SGS domain TPR_1 PF00515.28 GAM26856.1 - 3.8e-16 58.1 0.1 0.00017 21.3 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat CS PF04969.16 GAM26856.1 - 9.6e-14 52.2 1.9 1.7e-13 51.4 1.9 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 GAM26856.1 - 2.2e-13 49.2 0.0 0.0064 16.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM26856.1 - 6.4e-12 44.7 3.9 3.1e-05 23.8 0.0 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM26856.1 - 1e-06 28.3 0.0 0.011 15.4 0.0 3.5 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 GAM26856.1 - 1.1e-06 28.6 0.2 0.0098 16.2 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM26856.1 - 5.5e-06 26.5 0.8 0.0033 17.6 0.6 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GAM26856.1 - 9.4e-06 26.0 0.0 0.084 13.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM26856.1 - 1.5e-05 25.4 0.0 0.27 11.8 0.0 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM26856.1 - 1.8e-05 24.8 0.0 0.0021 18.2 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM26856.1 - 0.00012 22.3 0.0 0.36 11.2 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM26856.1 - 0.0018 18.2 0.0 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 GAM26856.1 - 0.028 13.3 0.0 0.028 13.3 0.0 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF5113 PF17140.4 GAM26856.1 - 0.029 14.2 0.1 0.072 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) Ank_2 PF12796.7 GAM26857.1 - 1.1e-07 32.4 11.4 0.56 10.8 0.0 8.1 6 2 3 9 9 9 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM26857.1 - 0.0005 20.3 4.3 2.4 9.0 0.0 7.9 10 0 0 10 10 10 1 Ankyrin repeat Ank_4 PF13637.6 GAM26857.1 - 0.0015 19.1 4.0 26 5.6 0.1 7.4 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Forkhead PF00250.18 GAM26857.1 - 0.016 15.4 0.1 0.064 13.5 0.1 2.0 1 0 0 1 1 1 0 Forkhead domain Ank_5 PF13857.6 GAM26857.1 - 0.11 12.8 5.4 42 4.6 1.8 6.4 7 1 1 8 8 8 0 Ankyrin repeats (many copies) Clathrin PF00637.20 GAM26857.1 - 0.6 10.0 8.0 8.6 6.2 1.0 3.9 4 0 0 4 4 4 0 Region in Clathrin and VPS Ank_2 PF12796.7 GAM26858.1 - 4.7e-07 30.3 2.9 0.22 12.1 0.3 4.9 5 0 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM26858.1 - 2.4 9.0 6.4 66 4.6 0.3 5.9 7 0 0 7 7 7 0 Ankyrin repeat Caveolin PF01146.17 GAM26859.1 - 0.095 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Caveolin Ank_2 PF12796.7 GAM26860.1 - 2.2e-09 37.8 1.4 0.075 13.6 0.1 5.3 5 2 2 7 7 7 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26860.1 - 0.0015 19.0 1.0 5.3 7.7 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26860.1 - 0.034 14.7 0.2 33 5.5 0.0 5.4 6 0 0 6 6 6 0 Ankyrin repeat Thy1 PF02511.15 GAM26860.1 - 0.037 13.8 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Thymidylate synthase complementing protein RICTOR_M PF14666.6 GAM26860.1 - 0.39 10.5 2.8 1.8 8.4 0.1 3.4 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR, middle domain Ank_2 PF12796.7 GAM26862.1 - 4.8e-08 33.5 6.1 0.42 11.2 0.0 6.4 6 1 1 7 7 7 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26862.1 - 0.0024 18.4 7.2 51 4.6 0.1 7.5 9 0 0 9 9 9 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM26862.1 - 0.021 15.1 1.1 39 4.7 0.1 5.0 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26862.1 - 0.046 14.3 10.7 26 5.8 0.1 8.6 11 0 0 11 11 11 0 Ankyrin repeat CUT PF02376.15 GAM26862.1 - 0.049 13.8 0.5 1.3 9.3 0.1 3.0 3 0 0 3 3 3 0 CUT domain Ank PF00023.30 GAM26862.1 - 0.069 13.6 1.2 88 3.8 0.0 5.5 4 2 1 5 5 5 0 Ankyrin repeat PBP1_TM PF14812.6 GAM26863.1 - 9.5 6.7 6.8 1.3e+02 3.1 6.2 3.0 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S28 PF05577.12 GAM26864.1 - 9.4e-110 367.4 3.0 1.1e-109 367.1 3.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 GAM26864.1 - 7.3e-06 24.9 0.1 1.1e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 GAM26864.1 - 0.00017 21.3 0.1 0.00056 19.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM26864.1 - 0.00019 20.8 0.0 0.00068 19.0 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM26864.1 - 0.014 14.9 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2920 PF11144.8 GAM26864.1 - 0.028 13.6 0.4 0.083 12.0 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2920) Lipase_3 PF01764.25 GAM26865.1 - 9.6e-23 80.6 0.0 1.6e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 GAM26865.1 - 0.025 14.1 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Nitrophorin PF02087.15 GAM26865.1 - 0.059 13.4 0.2 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Nitrophorin DUF676 PF05057.14 GAM26865.1 - 0.092 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Nckap1 PF09735.9 GAM26866.1 - 0 1173.9 8.4 0 1173.7 8.4 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Erf4 PF10256.9 GAM26867.1 - 9.2e-06 25.8 0.1 1.8e-05 24.8 0.1 1.4 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Peptidase_S74 PF13884.6 GAM26868.1 - 3.6e-13 49.6 0.0 7.2e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase NDT80_PhoG PF05224.12 GAM26868.1 - 4.2e-13 49.9 0.3 4.2e-13 49.9 0.3 5.9 4 2 0 4 4 4 1 NDT80 / PhoG like DNA-binding family DUF2975 PF11188.8 GAM26868.1 - 1.7 8.5 5.1 3.6 7.5 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Kelch_6 PF13964.6 GAM26870.1 - 5.6e-09 36.0 7.8 0.25 11.7 0.0 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 GAM26870.1 - 0.00012 22.0 9.4 0.41 10.7 0.1 4.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM26870.1 - 0.0027 17.6 3.4 1.2 9.2 0.2 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 GAM26870.1 - 0.017 15.1 3.2 1.4 9.0 0.1 3.0 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 GAM26870.1 - 0.12 12.7 0.7 31 5.0 0.0 4.2 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM26870.1 - 1.1 8.9 7.5 32 4.2 0.1 3.6 3 0 0 3 3 3 0 Kelch motif Utp21 PF04192.12 GAM26871.1 - 0.028 13.9 0.4 0.063 12.8 0.4 1.5 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Ank_3 PF13606.6 GAM26871.1 - 0.099 13.3 3.4 3.1e+02 2.5 0.0 7.5 8 0 0 8 8 8 0 Ankyrin repeat CN_hydrolase PF00795.22 GAM26872.1 - 7.5e-08 32.0 0.0 0.00071 19.0 0.0 2.2 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase S_100 PF01023.19 GAM26873.1 - 0.073 12.8 0.5 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain SAP30_Sin3_bdg PF13867.6 GAM26873.1 - 0.16 12.3 1.2 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 EGF_2 PF07974.13 GAM26874.1 - 0.0008 19.7 12.3 0.0016 18.7 12.3 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_alliinase PF04863.13 GAM26874.1 - 0.89 10.0 6.2 2.2 8.7 6.2 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain BCLP PF12304.8 GAM26875.1 - 0.038 13.5 0.5 0.038 13.5 0.5 2.1 2 0 0 2 2 2 0 Beta-casein like protein RseC_MucC PF04246.12 GAM26875.1 - 0.9 9.5 3.1 0.66 9.9 0.7 2.1 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC AhpC-TSA PF00578.21 GAM26878.1 - 5.8e-39 132.8 0.0 8.1e-39 132.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAM26878.1 - 5.5e-18 65.1 0.0 9.5e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GAM26878.1 - 2.1e-12 46.6 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin TRAPPC9-Trs120 PF08626.11 GAM26879.1 - 9e-73 245.3 2.7 1.1e-40 138.9 0.1 4.2 2 1 2 4 4 4 4 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Corona_S1 PF01600.16 GAM26879.1 - 0.014 14.2 0.4 0.025 13.4 0.4 1.3 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein Prefoldin PF02996.17 GAM26880.1 - 3.7e-13 49.4 0.2 3.7e-13 49.4 0.2 1.4 2 0 0 2 2 2 1 Prefoldin subunit DUF3144 PF11342.8 GAM26880.1 - 0.27 11.6 1.5 0.74 10.2 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3144) Glyco_hydro_38N PF01074.22 GAM26881.1 - 7.3e-68 229.0 3.9 7.8e-68 228.9 2.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAM26881.1 - 6.4e-15 55.8 2.6 1.3e-14 54.8 2.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAM26881.1 - 6.6e-15 55.0 0.4 1.7e-14 53.7 0.4 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Lyase_8_N PF08124.11 GAM26881.1 - 0.012 14.5 0.9 0.047 12.6 0.1 2.1 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain GW PF13457.6 GAM26881.1 - 2.2 8.9 5.9 4.3 8.0 0.4 3.0 2 0 0 2 2 2 0 GW (Gly-Tryp) dipeptide domain zf-RVT PF13966.6 GAM26883.1 - 0.0049 17.6 3.9 0.042 14.6 0.2 2.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Apo-CII PF05355.11 GAM26883.1 - 0.048 13.8 0.1 0.088 13.0 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein C-II Coiled PF05710.12 GAM26885.1 - 0.0017 19.1 7.0 0.002 18.9 7.0 1.1 1 0 0 1 1 1 1 Coiled coil DUF150 PF02576.17 GAM26886.1 - 0.57 10.6 3.1 0.74 10.3 0.1 2.7 3 0 0 3 3 3 0 RimP N-terminal domain LIM PF00412.22 GAM26887.1 - 3.4e-10 40.0 7.2 4.9e-10 39.5 7.2 1.2 1 0 0 1 1 1 1 LIM domain C1_1 PF00130.22 GAM26887.1 - 0.42 10.5 8.1 0.39 10.6 2.5 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Kelch_3 PF13415.6 GAM26888.1 - 0.16 12.3 0.6 7 7.1 0.0 2.8 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM26888.1 - 1.2 8.8 7.2 1.5 8.5 0.4 3.5 4 1 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 GAM26888.1 - 3.9 7.6 7.0 28 4.8 0.2 3.7 4 0 0 4 4 4 0 Galactose oxidase, central domain Ank_4 PF13637.6 GAM26889.1 - 1.1e-09 38.6 6.2 4.1 8.1 0.0 8.5 8 1 0 8 8 8 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM26889.1 - 2.7e-09 37.5 14.6 2.7 8.6 0.0 9.9 8 3 2 10 10 10 4 Ankyrin repeats (3 copies) Spo0A_C PF08769.11 GAM26889.1 - 0.0023 18.0 0.0 1.1 9.4 0.1 4.0 2 1 1 3 3 3 1 Sporulation initiation factor Spo0A C terminal Ank_5 PF13857.6 GAM26889.1 - 0.0029 17.9 1.7 28 5.2 0.0 6.9 7 1 1 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26889.1 - 0.23 12.1 12.8 2.3e+02 2.9 0.0 9.5 11 0 0 11 11 11 0 Ankyrin repeat Glyco_hydro_18 PF00704.28 GAM26890.1 - 3.4e-24 86.1 0.6 5.7e-24 85.4 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 F-box-like PF12937.7 GAM26891.1 - 0.0023 17.8 0.0 0.0071 16.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 GAM26891.1 - 0.071 13.7 0.6 39 5.4 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 GAM26891.1 - 4.2 7.7 7.4 29 5.1 0.4 4.2 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 GAM26892.1 - 3.7 8.1 11.6 0.67 10.5 0.1 4.6 3 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 GAM26893.1 - 1e-53 182.2 0.1 2.7e-52 177.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 GAM26893.1 - 1.1e-41 143.0 0.0 2.2e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 GAM26893.1 - 8.4e-35 120.3 0.1 4e-34 118.1 0.0 2.1 1 1 1 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 GAM26893.1 - 1.1e-07 32.0 0.0 3.8e-07 30.4 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase WD40_like PF17005.5 GAM26893.1 - 4.5e-06 26.2 2.2 2.3e-05 23.9 0.5 2.7 3 0 0 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 GAM26893.1 - 0.11 13.0 0.0 17 6.0 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain GLE1 PF07817.13 GAM26894.1 - 6.9e-54 182.7 4.0 6.9e-54 182.7 4.0 2.5 2 1 1 3 3 3 1 GLE1-like protein Ank_2 PF12796.7 GAM26895.1 - 0.0011 19.5 6.6 19 5.9 0.1 6.5 6 1 1 7 7 7 1 Ankyrin repeats (3 copies) Muskelin_N PF06588.11 GAM26895.1 - 0.0029 17.5 0.9 0.0076 16.2 0.9 1.7 1 0 0 1 1 1 1 Muskelin N-terminus Ank_3 PF13606.6 GAM26895.1 - 0.038 14.5 5.9 17 6.4 0.1 7.3 6 0 0 6 6 6 0 Ankyrin repeat Ank_4 PF13637.6 GAM26895.1 - 0.038 14.6 4.9 33 5.2 0.0 6.3 5 2 1 6 6 6 0 Ankyrin repeats (many copies) Snf7 PF03357.21 GAM26895.1 - 0.93 9.1 3.7 6.1 6.4 0.1 2.6 3 0 0 3 3 3 0 Snf7 Ank_2 PF12796.7 GAM26896.1 - 1.2e-08 35.4 12.5 3.4 8.3 0.0 7.9 6 2 1 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26896.1 - 3e-05 24.5 8.1 0.32 11.6 0.1 7.3 7 2 2 9 9 9 2 Ankyrin repeats (many copies) Glyco_hydro_18 PF00704.28 GAM26897.1 - 2e-24 86.9 1.2 2.8e-24 86.4 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Imm30 PF15565.6 GAM26898.1 - 0.056 13.5 0.3 2.2 8.4 0.0 3.6 3 1 0 3 3 3 0 Immunity protein 30 Ank_5 PF13857.6 GAM26898.1 - 0.52 10.7 3.7 23 5.5 0.3 4.0 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM26899.1 - 4.5e-05 23.9 1.6 10 6.8 0.0 5.4 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26899.1 - 0.17 12.6 9.1 70 4.5 0.1 6.9 8 0 0 8 8 8 0 Ankyrin repeat GNAT_acetyltr_2 PF13718.6 GAM26900.1 - 0.049 13.0 0.0 0.16 11.3 0.0 1.7 1 1 1 2 2 2 0 GNAT acetyltransferase 2 Ank_2 PF12796.7 GAM26901.1 - 1.6e-05 25.4 0.6 0.28 11.8 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26901.1 - 0.001 19.6 1.7 0.028 15.0 0.1 3.3 4 1 0 4 4 4 1 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 GAM26902.1 - 3.1e-15 55.8 12.0 5.1e-15 55.1 12.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM26902.1 - 3.4e-05 24.1 13.4 6.6e-05 23.2 13.4 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAM26902.1 - 4.9e-05 23.1 12.4 9.4e-05 22.2 12.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 HTH_AraC PF00165.23 GAM26902.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family zf-P11 PF03854.14 GAM26902.1 - 0.002 17.8 9.4 0.0053 16.4 9.4 1.7 1 0 0 1 1 1 1 P-11 zinc finger Serglycin PF04360.12 GAM26902.1 - 0.0021 18.0 2.6 0.0033 17.4 1.3 2.0 2 0 0 2 2 2 1 Serglycin zf-RING_5 PF14634.6 GAM26902.1 - 0.0087 16.0 11.3 0.017 15.1 11.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAM26902.1 - 0.086 12.7 13.2 0.16 11.8 13.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FtsH_ext PF06480.15 GAM26902.1 - 1.1 9.6 12.4 3.6 8.0 2.2 2.5 2 0 0 2 2 2 0 FtsH Extracellular Mucin PF01456.17 GAM26902.1 - 1.7 8.6 21.8 1.7 8.7 7.9 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein CDK2AP PF09806.9 GAM26902.1 - 2.3 8.2 8.1 1.3 9.1 2.4 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF3446 PF11928.8 GAM26902.1 - 3.8 7.9 12.8 1.5 9.2 1.1 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF3439 PF11921.8 GAM26902.1 - 9.6 6.2 21.9 0.49 10.4 4.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Kelch_6 PF13964.6 GAM26903.1 - 3.9e-05 23.8 6.3 0.017 15.4 0.1 4.8 4 2 1 5 5 5 2 Kelch motif Kelch_4 PF13418.6 GAM26903.1 - 0.007 16.3 5.8 0.2 11.7 0.1 4.6 4 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM26903.1 - 0.011 15.4 0.1 0.011 15.4 0.1 4.1 5 1 1 6 6 6 0 Kelch motif LptF_LptG PF03739.14 GAM26903.1 - 0.14 11.0 0.1 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Kelch_5 PF13854.6 GAM26903.1 - 0.56 10.3 3.9 2.9 8.0 0.2 3.5 4 0 0 4 4 4 0 Kelch motif FNIP PF05725.12 GAM26904.1 - 2.1e-71 235.8 42.3 5.8e-15 55.2 2.2 8.9 7 1 1 9 9 9 8 FNIP Repeat STAT6_C PF14596.6 GAM26904.1 - 0.13 12.2 1.2 0.3 11.0 0.1 2.3 3 0 0 3 3 3 0 STAT6 C-terminal ABC_tran PF00005.27 GAM26905.1 - 1.7e-33 116.0 0.0 2.7e-15 57.1 0.0 2.9 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 GAM26905.1 - 7.5e-14 51.3 6.1 1.9e-13 50.0 6.1 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 GAM26905.1 - 9.6e-13 48.1 1.4 0.0003 20.3 0.2 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAM26905.1 - 2.9e-10 40.5 6.3 0.062 13.1 0.0 4.2 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 GAM26905.1 - 4e-08 32.8 2.2 4e-08 32.8 2.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 GAM26905.1 - 1.1e-05 25.4 0.1 0.038 13.9 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 GAM26905.1 - 1.2e-05 25.7 0.0 0.065 13.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 GAM26905.1 - 1.4e-05 25.0 0.7 0.13 12.0 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 GAM26905.1 - 2.1e-05 24.8 0.0 0.027 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM26905.1 - 3.3e-05 24.3 0.0 0.2 12.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Fer4_6 PF12837.7 GAM26905.1 - 3.6e-05 23.7 11.9 4.8e-05 23.3 1.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.15 GAM26905.1 - 6.2e-05 23.0 0.0 0.058 13.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 GAM26905.1 - 0.0003 20.7 0.6 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 GAM26905.1 - 0.00031 20.4 0.5 0.89 9.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 GAM26905.1 - 0.00053 20.3 0.0 0.91 9.9 0.0 3.1 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.6 GAM26905.1 - 0.00068 19.8 0.0 0.27 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 GAM26905.1 - 0.0011 18.9 1.0 0.0011 18.9 1.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_24 PF13479.6 GAM26905.1 - 0.0017 18.1 0.8 0.31 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 GAM26905.1 - 0.0019 17.9 3.5 0.1 12.2 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 GAM26905.1 - 0.0032 17.7 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 GAM26905.1 - 0.0052 17.3 2.8 0.16 12.4 0.3 2.5 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 GAM26905.1 - 0.0067 16.6 12.4 0.023 14.9 12.6 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 GAM26905.1 - 0.0068 16.4 0.1 0.18 11.8 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_21 PF14697.6 GAM26905.1 - 0.0072 16.4 12.7 0.019 15.1 12.8 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain AAA_14 PF13173.6 GAM26905.1 - 0.0089 16.1 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 GAM26905.1 - 0.01 16.0 1.6 0.01 16.0 1.6 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_7 PF12775.7 GAM26905.1 - 0.011 15.3 0.2 0.2 11.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 GAM26905.1 - 0.015 15.0 0.5 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 GAM26905.1 - 0.016 14.9 0.5 2.5 7.7 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase Fer4_7 PF12838.7 GAM26905.1 - 0.018 15.6 1.9 0.018 15.6 1.9 2.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain AAA_18 PF13238.6 GAM26905.1 - 0.022 15.3 0.0 8 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 GAM26905.1 - 0.027 15.4 0.3 0.027 15.4 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Zeta_toxin PF06414.12 GAM26905.1 - 0.039 13.2 0.6 0.71 9.1 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 GAM26905.1 - 0.039 14.0 0.0 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase VirE PF05272.11 GAM26905.1 - 0.068 12.9 0.1 11 5.6 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E DUF815 PF05673.13 GAM26905.1 - 0.12 11.5 0.0 5.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 GAM26905.1 - 0.16 11.1 0.2 15 4.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 GAM26905.1 - 0.19 10.7 0.2 2 7.3 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 GAM26905.1 - 0.23 11.4 1.1 9.1 6.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.14 GAM26905.1 - 0.23 11.4 0.7 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 GAM26905.1 - 0.51 10.2 3.3 9.8 6.1 0.0 3.0 3 0 0 3 3 2 0 NTPase Ribosomal_L31e PF01198.19 GAM26906.1 - 1.3e-34 118.3 0.2 1.8e-34 117.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Pan3_PK PF18101.1 GAM26907.1 - 1.2e-58 196.9 0.3 1.2e-58 196.9 0.3 2.4 4 1 0 4 4 4 1 Pan3 Pseudokinase domain Pkinase PF00069.25 GAM26907.1 - 2.9e-10 40.0 0.0 2.9e-10 40.0 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26907.1 - 0.00015 21.2 0.0 0.00015 21.2 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase RR_TM4-6 PF06459.12 GAM26907.1 - 0.41 10.4 18.4 0.72 9.6 18.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 2OG-FeII_Oxy_2 PF13532.6 GAM26908.1 - 1.1e-18 68.1 0.0 2.1e-18 67.2 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAM26908.1 - 2.4e-05 24.7 0.0 4.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CDP-OH_P_transf PF01066.21 GAM26909.1 - 1.6e-17 64.0 0.1 1.6e-17 64.0 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2715 PF10895.8 GAM26909.1 - 0.034 13.8 0.2 0.041 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) Acetyltransf_1 PF00583.25 GAM26910.1 - 1.9e-06 28.1 0.0 3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 GAM26910.1 - 0.0012 18.5 0.1 0.0028 17.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM26910.1 - 0.064 13.4 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM26910.1 - 0.087 12.8 0.1 3.2 7.8 0.0 2.5 2 0 0 2 2 2 0 FR47-like protein CH PF00307.31 GAM26911.1 - 1.7e-42 144.0 7.1 1.4e-22 79.9 0.1 3.9 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM26911.1 - 6.2e-12 45.2 0.4 3.5e-07 30.0 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 GAM26911.1 - 3.7e-06 27.0 0.1 0.03 14.4 0.0 3.2 2 0 0 2 2 2 2 CH-like domain in sperm protein GAS PF13851.6 GAM26911.1 - 0.00027 20.3 26.7 0.00027 20.3 26.7 10.0 3 1 7 10 10 10 1 Growth-arrest specific micro-tubule binding zinc_ribbon_10 PF10058.9 GAM26912.1 - 8.2e-17 60.7 0.3 1.5e-16 59.9 0.3 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Frag1 PF10277.9 GAM26912.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family TFIIA PF03153.13 GAM26912.1 - 0.091 12.7 9.4 0.12 12.3 9.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-Dof PF02701.15 GAM26912.1 - 0.091 12.9 0.4 0.091 12.9 0.4 1.9 2 0 0 2 2 2 0 Dof domain, zinc finger DUF2981 PF11200.8 GAM26912.1 - 0.58 9.9 2.8 1 9.0 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4199 PF13858.6 GAM26912.1 - 4.8 7.6 6.8 0.74 10.2 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) DUF3290 PF11694.8 GAM26912.1 - 5.3 7.0 8.6 0.69 9.9 4.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3290) DUF4282 PF14110.6 GAM26913.1 - 6.7e-06 26.8 7.5 9e-06 26.3 7.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) SET PF00856.28 GAM26914.1 - 0.00062 20.2 0.1 0.00076 19.9 0.1 1.2 1 0 0 1 1 1 1 SET domain Ribosomal_L31e PF01198.19 GAM26914.1 - 0.0092 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31e TPR_12 PF13424.6 GAM26915.1 - 0.033 14.5 0.2 7 7.0 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3972 PF13118.6 GAM26915.1 - 0.06 13.8 1.6 0.7 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) Lyase_aromatic PF00221.19 GAM26915.1 - 0.06 12.0 0.1 4.2 5.9 0.0 2.0 2 0 0 2 2 2 0 Aromatic amino acid lyase DDE_Tnp_4 PF13359.6 GAM26916.1 - 1.5e-27 96.2 0.0 1.7e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM26916.1 - 5.5e-11 42.5 0.0 7.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Chromo PF00385.24 GAM26917.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain FG-GAP_2 PF14312.6 GAM26918.1 - 0.00043 20.5 0.1 0.11 12.8 0.0 3.0 3 0 0 3 3 3 2 FG-GAP repeat Ephrin_rec_like PF07699.13 GAM26918.1 - 0.0087 15.8 5.4 0.032 14.0 5.4 2.1 1 1 0 1 1 1 1 Putative ephrin-receptor like DUF3689 PF12463.8 GAM26919.1 - 1.2e-24 87.2 5.2 3.6e-22 79.1 3.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3689) BTB PF00651.31 GAM26920.1 - 1.2e-22 80.3 1.2 9.5e-22 77.3 0.3 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 GAM26920.1 - 0.00029 20.9 0.2 0.0032 17.6 0.0 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF1265 PF06887.14 GAM26920.1 - 0.033 14.2 0.2 0.061 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) Rsm22 PF09243.10 GAM26921.1 - 3.5e-71 239.7 0.0 8.3e-71 238.5 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 GAM26921.1 - 1.2e-09 38.2 0.1 1.9e-08 34.3 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM26921.1 - 6.2e-05 23.6 0.0 0.0011 19.5 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM26921.1 - 0.0012 19.6 0.0 0.019 15.7 0.0 3.2 4 0 0 4 4 4 1 Methyltransferase domain SUIM_assoc PF16619.5 GAM26921.1 - 0.0026 17.8 9.8 0.0026 17.8 9.8 5.8 4 1 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 Ubie_methyltran PF01209.18 GAM26921.1 - 0.0053 16.1 0.0 0.041 13.2 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Glyco_hydro_38N PF01074.22 GAM26922.1 - 1e-77 261.4 4.1 5.6e-77 258.9 0.8 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAM26922.1 - 3.9e-17 63.0 0.2 6.4e-17 62.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAM26922.1 - 8.1e-11 41.9 0.1 2.1e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAM26922.1 - 2.1e-06 27.7 0.0 5.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF4861 PF16153.5 GAM26922.1 - 0.039 12.9 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) PH PF00169.29 GAM26923.1 - 1.2e-16 61.1 0.0 2.3e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 GAM26923.1 - 4.7e-05 23.4 0.0 6.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM26923.1 - 4.9e-05 23.5 0.1 9.6e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAM26923.1 - 0.00031 21.1 0.2 0.00031 21.1 0.2 3.1 2 2 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.6 GAM26923.1 - 0.011 16.0 0.3 0.11 12.9 0.3 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain Macoilin PF09726.9 GAM26923.1 - 0.09 11.3 11.3 0.097 11.2 11.3 1.1 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 GAM26923.1 - 3.8 5.7 9.2 4.6 5.5 9.2 1.1 1 0 0 1 1 1 0 Menin NUDE_C PF04880.13 GAM26923.1 - 4.3 7.8 16.2 7.2 7.1 16.2 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region QWRF PF04484.12 GAM26923.1 - 7.1 6.3 16.0 9.4 5.9 16.0 1.2 1 0 0 1 1 1 0 QWRF family Sarcoglycan_1 PF04790.13 GAM26924.1 - 0.57 9.5 2.8 0.84 8.9 2.8 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein MASE4 PF17158.4 GAM26924.1 - 0.86 8.8 11.4 4.1 6.6 6.6 2.3 2 1 1 3 3 3 0 Membrane-associated sensor, integral membrane domain DHR-2 PF06920.13 GAM26925.1 - 1.8e-49 168.8 2.3 5e-49 167.3 2.3 1.7 1 0 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 GAM26925.1 - 9.3e-46 156.4 0.3 7.5e-35 120.5 0.0 2.5 2 0 0 2 2 2 2 DOCK N-terminus DOCK-C2 PF14429.6 GAM26925.1 - 2.4e-27 96.0 0.0 7.7e-27 94.4 0.0 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 GAM26925.1 - 1.2e-06 28.2 0.0 2.8e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM26925.1 - 0.025 14.2 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 SH3 domain DUF4363 PF14276.6 GAM26925.1 - 0.063 13.4 0.6 23 5.2 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) PI3K_C2 PF00792.24 GAM26925.1 - 0.077 12.9 0.3 0.79 9.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 Condensin2nSMC PF12422.8 GAM26925.1 - 0.47 10.6 3.2 8.3 6.6 0.1 3.0 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit RPAP2_Rtr1 PF04181.13 GAM26926.1 - 1.8e-19 69.8 0.8 4.5e-19 68.5 0.8 1.7 1 0 0 1 1 1 1 Rtr1/RPAP2 family Glyco_hydro_57 PF03065.15 GAM26927.1 - 5.3e-09 35.7 0.0 1.6e-08 34.1 0.0 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 ComC PF03047.14 GAM26928.1 - 0.035 13.9 0.2 0.098 12.5 0.2 1.8 1 0 0 1 1 1 0 COMC family Ank_2 PF12796.7 GAM26929.1 - 0.00089 19.8 0.8 0.18 12.4 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM26929.1 - 0.0019 18.8 4.3 0.79 10.4 0.2 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26929.1 - 0.007 16.8 2.2 0.057 14.0 0.1 3.4 4 0 0 4 4 4 1 Ankyrin repeat VWA_3_C PF18571.1 GAM26929.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain Ank_4 PF13637.6 GAM26932.1 - 2.4e-05 24.8 7.2 1.2 9.8 0.1 7.5 7 1 1 8 8 8 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM26932.1 - 7.4e-05 23.3 8.2 0.96 10.1 0.1 6.9 7 1 2 9 9 9 2 Ankyrin repeats (3 copies) MapZ_C2 PF18708.1 GAM26932.1 - 0.051 13.9 0.1 8.2 6.8 0.0 2.9 1 1 1 2 2 2 0 MapZ extracellular C-terminal domain 2 Ank_5 PF13857.6 GAM26933.1 - 0.0013 18.9 1.6 2.4 8.6 1.2 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26933.1 - 0.041 14.4 0.2 6.8 7.6 0.2 3.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 GAM26933.1 - 0.066 13.8 1.2 0.74 10.4 0.6 2.6 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM26934.1 - 0.035 14.6 0.0 1.1 10.0 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 GAM26934.1 - 0.074 13.6 0.2 0.84 10.3 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM26934.1 - 0.14 12.5 0.0 11 6.5 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM26935.1 - 0.053 14.1 0.1 28 5.4 0.1 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF4748 PF15932.5 GAM26935.1 - 0.11 12.2 0.6 0.23 11.3 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) FNIP PF05725.12 GAM26938.1 - 4.4e-53 177.2 9.2 2.8e-16 59.4 0.0 6.2 4 1 2 6 6 6 6 FNIP Repeat DUF5536 PF17688.1 GAM26938.1 - 0.017 15.0 0.0 3.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5536) Ank_2 PF12796.7 GAM26939.1 - 5.6e-05 23.7 13.5 0.12 12.9 0.2 6.1 6 2 1 8 8 8 2 Ankyrin repeats (3 copies) RasGEF_N PF00618.20 GAM26939.1 - 0.0051 17.0 0.1 0.018 15.3 0.1 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Ank_4 PF13637.6 GAM26939.1 - 0.0067 17.0 7.9 4 8.1 0.0 6.0 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26939.1 - 0.071 13.7 9.8 18 6.3 0.0 7.3 9 0 0 9 9 9 0 Ankyrin repeat Ank_5 PF13857.6 GAM26940.1 - 3.9e-07 30.2 4.0 21 5.6 0.1 9.9 10 1 1 11 11 11 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM26940.1 - 4.5e-05 23.5 4.9 57 4.8 0.1 9.5 10 0 0 10 10 10 1 Ankyrin repeat FNIP PF05725.12 GAM26941.1 - 0.0033 17.6 12.9 1.1 9.5 0.3 5.7 6 1 0 6 6 6 3 FNIP Repeat CDC50 PF03381.15 GAM26942.1 - 5.9e-78 262.2 0.0 8.8e-78 261.6 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Neurensin PF14927.6 GAM26942.1 - 0.018 14.7 0.0 6.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Neurensin DUF3040 PF11239.8 GAM26942.1 - 0.028 14.7 0.7 0.26 11.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF202 PF02656.15 GAM26942.1 - 0.05 14.1 0.3 6.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) CUB_2 PF02408.20 GAM26942.1 - 0.11 12.2 0.2 0.19 11.5 0.2 1.3 1 0 0 1 1 1 0 CUB-like domain TMEM238 PF15125.6 GAM26942.1 - 0.14 12.4 3.7 0.57 10.4 1.7 2.2 2 0 0 2 2 2 0 TMEM238 protein family DUF3185 PF11381.8 GAM26942.1 - 1.5 8.9 6.1 11 6.1 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Pkinase PF00069.25 GAM26943.1 - 4.2e-74 249.2 0.0 9.3e-74 248.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26943.1 - 1.6e-48 165.3 0.0 2.9e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM26943.1 - 4e-06 25.9 0.7 6.3e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase CSTF2_hinge PF14327.6 GAM26943.1 - 0.0006 20.2 0.8 0.0006 20.2 0.8 2.9 3 0 0 3 3 2 1 Hinge domain of cleavage stimulation factor subunit 2 Arm PF00514.23 GAM26943.1 - 0.0012 18.8 2.2 6.8 6.9 0.0 5.1 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 GAM26943.1 - 0.0015 17.9 0.0 0.021 14.1 0.0 2.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 GAM26943.1 - 0.012 15.2 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Adaptin_N PF01602.20 GAM26943.1 - 0.015 13.9 8.0 0.057 12.0 2.9 2.5 2 0 0 2 2 2 0 Adaptin N terminal region FTA2 PF13095.6 GAM26943.1 - 0.023 14.3 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RICTOR_N PF14664.6 GAM26943.1 - 0.033 13.2 4.8 2.1 7.2 0.1 3.2 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term Kdo PF06293.14 GAM26943.1 - 0.035 13.4 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ParcG PF10274.9 GAM26943.1 - 0.12 12.5 3.4 0.1 12.7 0.7 2.2 2 0 0 2 2 2 0 Parkin co-regulated protein V-ATPase_H_C PF11698.8 GAM26943.1 - 0.39 10.8 5.7 0.13 12.4 2.1 2.1 2 0 0 2 2 2 0 V-ATPase subunit H DUF3385 PF11865.8 GAM26943.1 - 1.1 9.2 11.1 5 7.0 1.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3385) Oxysterol_BP PF01237.18 GAM26944.1 - 1.9e-47 161.9 17.0 4.2e-45 154.2 2.2 2.9 1 1 2 3 3 3 3 Oxysterol-binding protein DUF1084 PF06454.11 GAM26945.1 - 1e-17 64.5 14.5 1.1e-17 64.3 14.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) EamA PF00892.20 GAM26945.1 - 0.061 13.5 0.8 0.061 13.5 0.8 3.8 2 1 2 4 4 4 0 EamA-like transporter family CrgA PF06781.12 GAM26945.1 - 1.4 9.0 11.3 0.37 10.9 1.1 3.6 3 1 0 3 3 3 0 Cell division protein CrgA WD40 PF00400.32 GAM26946.1 - 4.5e-17 62.1 7.1 0.0019 19.0 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat F-box-like PF12937.7 GAM26946.1 - 5e-10 39.1 0.2 1.2e-09 37.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM26946.1 - 8e-08 32.0 0.3 1.8e-07 30.8 0.3 1.7 1 0 0 1 1 1 1 F-box domain START PF01852.19 GAM26946.1 - 0.00012 21.6 0.2 0.00096 18.6 0.0 2.3 2 0 0 2 2 2 1 START domain SSP160 PF06933.11 GAM26946.1 - 3.5 5.7 14.1 5.4 5.1 14.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.11 GAM26946.1 - 5.7 4.9 8.4 1 7.3 4.0 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Mucin PF01456.17 GAM26946.1 - 6 6.9 18.1 0.028 14.4 8.7 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Pim PF16765.5 GAM26947.1 - 0.096 12.8 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Pesticin immunity protein Glyco_transf_49 PF13896.6 GAM26948.1 - 1.5e-51 175.7 1.3 3.4e-43 148.3 0.5 2.7 2 1 1 3 3 3 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAM26948.1 - 0.0017 18.2 0.8 0.0023 17.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Menin PF05053.13 GAM26948.1 - 6.2 5.1 9.1 8.2 4.7 9.1 1.1 1 0 0 1 1 1 0 Menin DUF1084 PF06454.11 GAM26950.1 - 8.8e-13 48.2 19.9 1.1e-12 47.9 19.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF2976 PF11190.8 GAM26950.1 - 0.0063 16.3 1.5 0.0063 16.3 1.5 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF2976) CYYR1 PF10873.8 GAM26950.1 - 4 7.9 5.7 0.56 10.6 0.7 2.1 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 PRK PF00485.18 GAM26951.1 - 2.8e-07 30.5 0.0 3.7e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAM26951.1 - 3.2e-07 30.9 0.0 2e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAM26951.1 - 5.6e-05 23.3 0.1 0.00031 20.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 GAM26951.1 - 0.00027 21.0 0.0 0.00046 20.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rad17 PF03215.15 GAM26951.1 - 0.00077 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 GAM26951.1 - 0.00093 19.0 0.1 0.0045 16.8 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase MeaB PF03308.16 GAM26951.1 - 0.0013 17.8 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 GAM26951.1 - 0.002 17.4 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.27 GAM26951.1 - 0.0022 18.5 0.0 0.0037 17.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter dNK PF01712.19 GAM26951.1 - 0.0026 17.7 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase SKI PF01202.22 GAM26951.1 - 0.0031 17.6 0.0 1.8 8.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase RuvB_N PF05496.12 GAM26951.1 - 0.0036 17.0 0.1 0.0075 16.0 0.1 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 GAM26951.1 - 0.0057 17.1 0.0 0.0096 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 GAM26951.1 - 0.0071 16.3 0.0 0.019 14.9 0.0 1.8 2 1 0 2 2 2 1 NTPase NB-ARC PF00931.22 GAM26951.1 - 0.0091 15.2 0.0 0.041 13.1 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 GAM26951.1 - 0.013 15.9 0.2 0.024 15.0 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 GAM26951.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 GAM26951.1 - 0.029 14.3 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 GAM26951.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GAM26951.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain PyocinActivator PF11112.8 GAM26951.1 - 0.071 13.3 0.1 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Pyocin activator protein PrtN AAA_17 PF13207.6 GAM26951.1 - 0.082 13.3 0.4 0.44 11.0 0.0 2.3 3 0 0 3 3 2 0 AAA domain 6PF2K PF01591.18 GAM26951.1 - 0.098 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_11 PF13086.6 GAM26951.1 - 0.11 12.3 0.1 0.21 11.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 GAM26951.1 - 0.15 11.7 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase F-box PF00646.33 GAM26952.1 - 0.0022 17.8 0.5 0.0022 17.8 0.5 2.6 3 0 0 3 3 3 1 F-box domain Vps5 PF09325.10 GAM26952.1 - 0.082 12.4 0.4 0.19 11.3 0.4 1.5 1 0 0 1 1 1 0 Vps5 C terminal like JCAD PF15351.6 GAM26952.1 - 0.22 9.2 0.0 0.32 8.7 0.0 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Helo_like_N PF17111.5 GAM26954.1 - 0.077 12.3 0.2 0.14 11.5 0.1 1.5 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF4932 PF16286.5 GAM26954.1 - 0.19 11.0 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) Adeno_E3_CR2 PF02439.15 GAM26955.1 - 0.026 14.3 0.7 0.06 13.1 0.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAP10 PF07213.11 GAM26955.1 - 0.062 13.3 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 DAP10 membrane protein EGF_2 PF07974.13 GAM26955.1 - 1.1 9.7 14.7 2.5 8.5 14.7 1.7 1 0 0 1 1 1 0 EGF-like domain Melibiase_2 PF16499.5 GAM26956.1 - 6.9e-77 258.4 2.6 1.1e-76 257.8 2.6 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 GAM26956.1 - 5.3e-24 84.1 0.1 8.3e-22 77.1 0.1 2.5 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 GAM26956.1 - 6.5e-06 26.3 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 GAM26956.1 - 1.1e-05 24.6 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_30C PF17189.4 GAM26956.1 - 0.047 13.9 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain Raffinose_syn PF05691.12 GAM26956.1 - 0.11 10.2 0.1 0.16 9.7 0.1 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 DHHC PF01529.20 GAM26957.1 - 2e-37 128.3 8.5 2e-37 128.3 8.5 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF2207 PF09972.9 GAM26957.1 - 0.021 13.6 0.1 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Spt4 PF06093.13 GAM26957.1 - 0.72 10.0 6.0 1.6 8.9 6.0 1.6 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger DUF975 PF06161.11 GAM26957.1 - 1.1 9.0 9.9 0.81 9.4 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF975) NST1 PF13945.6 GAM26960.1 - 2.3 8.3 13.7 5.3 7.1 13.7 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator Dicty_REP PF05086.12 GAM26960.1 - 2.6 5.9 9.4 3.3 5.6 9.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Membralin PF09746.9 GAM26960.1 - 2.7 6.9 5.8 4.4 6.3 5.8 1.3 1 0 0 1 1 1 0 Tumour-associated protein Ank_5 PF13857.6 GAM26962.1 - 0.0023 18.2 1.8 11 6.4 0.0 5.3 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM26962.1 - 0.018 15.6 4.7 2.2 8.9 0.1 4.6 2 2 0 4 4 4 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM26962.1 - 0.58 10.9 2.3 27 5.8 0.0 4.7 6 1 0 6 6 6 0 Ankyrin repeat TFIIS_M PF07500.14 GAM26963.1 - 2.2e-15 57.1 0.3 4.8e-15 56.0 0.3 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 GAM26963.1 - 6e-08 32.6 2.5 7.2e-08 32.3 1.2 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain MRP-S25 PF13741.6 GAM26963.1 - 0.037 13.6 2.8 0.056 13.0 2.8 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 Pacs-1 PF10254.9 GAM26963.1 - 0.12 11.3 8.0 0.16 10.9 8.0 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Pox_A_type_inc PF04508.12 GAM26963.1 - 0.35 10.8 1.4 1.6 8.7 0.0 2.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat ORC6 PF05460.13 GAM26963.1 - 0.41 9.9 15.0 0.52 9.5 15.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TPR_1 PF00515.28 GAM26964.1 - 3.5e-44 146.9 3.3 2.1e-07 30.4 0.0 8.7 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.17 GAM26964.1 - 7.7e-36 119.3 4.3 1.3e-06 28.1 0.0 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 GAM26964.1 - 1.7e-25 87.1 3.0 4.1e-05 23.4 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAM26964.1 - 9e-22 76.5 4.1 3.7e-05 23.3 0.0 7.5 5 1 2 7 7 7 5 TPR repeat TPR_12 PF13424.6 GAM26964.1 - 2.2e-20 72.7 7.4 0.00031 20.9 0.2 6.9 5 1 2 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAM26964.1 - 2.4e-17 63.3 0.0 6.6e-05 23.5 0.0 4.7 4 1 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM26964.1 - 4e-17 61.3 1.6 0.0014 18.9 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAM26964.1 - 1e-12 48.0 0.1 0.015 15.4 0.1 5.5 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAM26964.1 - 1.3e-10 40.5 2.0 0.036 14.1 0.0 6.4 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAM26964.1 - 5e-10 39.4 1.7 0.053 14.2 0.2 6.6 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM26964.1 - 6.6e-10 39.0 1.6 0.62 11.0 0.0 6.7 2 1 5 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM26964.1 - 1.1e-09 38.4 1.1 0.0038 17.4 0.1 3.8 2 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAM26964.1 - 2.2e-09 37.7 0.2 0.0055 17.2 0.0 5.7 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM26964.1 - 3.5e-05 23.5 4.4 1.2 9.1 0.1 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 GAM26964.1 - 0.00019 21.5 2.1 0.17 11.9 0.7 3.7 3 1 0 3 3 3 1 Putative TPR-like repeat NARP1 PF12569.8 GAM26964.1 - 0.0018 17.3 5.8 0.4 9.5 0.1 4.7 2 2 2 6 6 6 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 GAM26964.1 - 0.0058 16.9 0.2 2.3 8.6 0.0 4.1 2 2 1 4 4 4 1 Tetratricopeptide repeat ACP_PD PF04336.12 GAM26964.1 - 0.013 15.9 4.4 0.28 11.6 0.4 3.9 3 1 1 4 4 4 0 Acyl carrier protein phosphodiesterase DUF5113 PF17140.4 GAM26964.1 - 0.028 14.2 4.9 10 5.9 0.2 4.3 2 1 3 5 5 5 0 Domain of unknown function (DUF5113) Phage_int_SAM_1 PF02899.17 GAM26964.1 - 0.04 14.2 1.6 6.8 7.1 0.1 3.4 3 1 0 3 3 2 0 Phage integrase, N-terminal SAM-like domain Orbi_VP5 PF00901.17 GAM26964.1 - 0.072 11.5 0.2 0.11 10.9 0.2 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Fis1_TPR_C PF14853.6 GAM26964.1 - 0.082 13.0 4.0 12 6.0 0.1 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_5 PF12688.7 GAM26964.1 - 0.086 13.1 0.2 5.5 7.3 0.0 3.2 3 0 0 3 3 2 0 Tetratrico peptide repeat Orthopox_B11R PF07033.11 GAM26964.1 - 0.24 11.2 0.6 0.75 9.6 0.1 2.0 2 0 0 2 2 2 0 Orthopoxvirus B11R protein ENTH PF01417.20 GAM26965.1 - 0.016 15.2 0.5 0.067 13.2 0.3 2.1 2 0 0 2 2 2 0 ENTH domain MRP_L53 PF10780.9 GAM26965.1 - 0.21 11.8 0.6 2.5 8.3 0.0 3.0 4 0 0 4 4 4 0 39S ribosomal protein L53/MRP-L53 DpnI_C PF17726.1 GAM26965.1 - 0.27 11.4 4.2 9 6.5 0.2 3.2 3 0 0 3 3 3 0 Dam-replacing HTH domain Ank_2 PF12796.7 GAM26965.1 - 0.38 11.4 9.9 29 5.4 0.7 5.1 4 1 1 5 5 5 0 Ankyrin repeats (3 copies) HA2 PF04408.23 GAM26966.1 - 1.7e-26 92.6 0.0 1.7e-26 92.6 0.0 2.4 2 1 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAM26966.1 - 2.1e-24 85.7 0.0 4.4e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAM26966.1 - 2.5e-12 47.1 0.0 1.2e-11 44.9 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain S1 PF00575.23 GAM26966.1 - 1.5e-11 44.5 0.6 3.7e-11 43.2 0.6 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 GAM26966.1 - 4.1e-07 29.9 0.0 1.9e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAM26966.1 - 4.5e-05 23.7 0.1 0.00013 22.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAM26966.1 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAM26966.1 - 0.0096 15.0 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 GAM26966.1 - 0.023 15.1 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 GAM26966.1 - 0.027 14.5 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.16 GAM26966.1 - 0.063 12.7 0.5 0.31 10.5 0.1 2.3 3 0 0 3 3 3 0 PhoH-like protein FtsK_SpoIIIE PF01580.18 GAM26966.1 - 0.13 11.6 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DAGK_cat PF00781.24 GAM26967.1 - 4.1e-28 97.5 0.0 9e-28 96.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3456 PF11938.8 GAM26967.1 - 0.0021 18.6 0.1 0.0063 17.0 0.1 1.8 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP SF3A3 PF16837.5 GAM26967.1 - 0.033 14.7 0.2 0.096 13.2 0.2 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Spectrin_like PF18373.1 GAM26967.1 - 0.047 13.8 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Spectrin like domain Apt1 PF10351.9 GAM26967.1 - 0.14 11.0 5.8 0.25 10.1 5.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAD_kinase PF01513.21 GAM26967.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 ATP-NAD kinase NADH_dehy_S2_C PF06444.11 GAM26967.1 - 4 8.0 7.2 11 6.7 7.2 1.7 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus Yae1_N PF09811.9 GAM26968.1 - 9.6e-10 38.0 5.0 1.1e-09 37.8 4.1 1.6 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Amidinotransf PF02274.17 GAM26969.1 - 6.7e-66 222.7 2.6 1.1e-52 179.2 0.0 4.3 3 2 0 3 3 3 3 Amidinotransferase BDV_M PF16520.5 GAM26969.1 - 0.045 14.1 0.1 0.28 11.6 0.1 2.3 2 0 0 2 2 2 0 ssRNA-binding matrix protein of Bornaviridae PAD_porph PF04371.15 GAM26969.1 - 0.095 12.0 0.3 0.31 10.3 0.3 1.8 1 1 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase FNIP PF05725.12 GAM26970.1 - 1.4e-09 38.0 11.6 2.3e-05 24.5 0.8 3.7 2 1 1 3 3 3 3 FNIP Repeat Kelch_6 PF13964.6 GAM26971.1 - 5.7e-11 42.3 4.1 0.00041 20.5 0.0 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM26971.1 - 2.8e-05 24.0 10.5 0.11 12.5 0.1 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM26971.1 - 4.3e-05 23.3 5.5 1.5 8.9 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAM26971.1 - 0.0019 18.4 13.6 0.25 11.7 0.0 5.8 7 1 0 7 7 7 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM26971.1 - 0.003 17.1 9.8 0.27 10.9 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 GAM26971.1 - 0.65 10.1 9.5 17 5.5 0.0 4.3 5 0 0 5 5 5 0 Kelch motif Peptidase_C1 PF00112.23 GAM26972.1 - 1.1e-72 244.7 10.9 6.3e-60 203.0 3.8 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM26972.1 - 5.3e-15 55.6 1.9 1e-14 54.7 1.9 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAM26972.1 - 0.00016 20.6 1.4 0.046 12.5 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family NTNH_C PF08470.10 GAM26972.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal eIF_4EBP PF05456.11 GAM26973.1 - 1.4e-23 83.0 2.6 1.6e-23 82.8 2.6 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) GTP_EFTU PF00009.27 GAM26974.1 - 4.3e-24 85.1 0.0 8e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAM26974.1 - 4.2e-09 36.7 2.5 6.5e-09 36.1 0.6 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM26974.1 - 0.001 19.1 0.2 0.0037 17.3 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ImcF-related_N PF14331.6 GAM26974.1 - 0.052 12.9 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 ImcF-related N-terminal domain PduV-EutP PF10662.9 GAM26974.1 - 0.052 13.3 0.1 53 3.6 0.0 3.5 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 GAM26974.1 - 0.087 13.3 0.5 0.28 11.7 0.1 2.0 3 0 0 3 3 3 0 ABC transporter DUF5627 PF18620.1 GAM26974.1 - 3.3 7.6 5.6 9.2 6.1 5.6 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5627) p450 PF00067.22 GAM26975.1 - 1.9e-44 152.2 0.1 2.7e-44 151.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 PBP1_TM PF14812.6 GAM26975.1 - 0.22 11.9 1.0 0.62 10.5 1.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 GAM26976.1 - 4.6e-38 131.0 19.7 8.2e-22 77.6 6.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM26976.1 - 7.8e-13 48.1 19.2 2.7e-12 46.3 19.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 GAM26976.1 - 0.01 14.4 12.2 0.0048 15.5 5.0 2.6 1 1 1 2 2 2 0 MFS/sugar transport protein DUF3671 PF12420.8 GAM26976.1 - 1.3 9.1 7.3 14 5.8 2.6 3.3 2 1 0 2 2 2 0 Protein of unknown function Peptidase_M15 PF01427.17 GAM26978.1 - 0.014 15.2 0.1 0.014 15.2 0.1 1.7 2 0 0 2 2 2 0 D-ala-D-ala dipeptidase zf-CHC2 PF01807.20 GAM26979.1 - 0.96 9.3 5.8 1.6 8.6 4.8 1.9 1 1 0 1 1 1 0 CHC2 zinc finger Pinin_SDK_memA PF04696.13 GAM26980.1 - 2.7e-16 59.8 10.3 2.7e-16 59.8 10.3 4.3 3 2 1 4 4 4 1 pinin/SDK/memA/ protein conserved region DUF2201_N PF13203.6 GAM26980.1 - 0.012 15.2 7.0 0.065 12.8 0.0 3.3 1 1 2 3 3 3 0 Putative metallopeptidase domain FNIP PF05725.12 GAM26981.1 - 2.1e-20 72.6 24.9 3.2e-05 24.0 0.5 8.4 5 2 4 9 9 9 7 FNIP Repeat A2M PF00207.22 GAM26981.1 - 0.16 11.8 0.9 1.8 8.5 0.0 2.9 3 0 0 3 3 3 0 Alpha-2-macroglobulin family DarA_C PF18789.1 GAM26981.1 - 0.27 11.6 1.5 8.8 6.7 0.2 2.6 1 1 1 2 2 2 0 Defence against restriction A C-terminal LRR_4 PF12799.7 GAM26981.1 - 5.8 7.5 6.9 46 4.6 0.9 3.8 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) FNIP PF05725.12 GAM26982.1 - 2.9e-20 72.2 30.2 9.5e-07 28.9 4.3 7.9 6 2 2 8 8 8 6 FNIP Repeat AAA_14 PF13173.6 GAM26982.1 - 0.0048 16.9 0.0 0.008 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RVT_1 PF00078.27 GAM26984.1 - 8.8e-06 25.4 0.4 1.5e-05 24.7 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 GAM26985.1 - 3.8e-05 23.3 0.1 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Porin_5 PF16930.5 GAM26987.1 - 0.04 12.4 0.4 0.61 8.5 0.0 2.5 2 1 1 3 3 3 0 Putative porin RYDR_ITPR PF01365.21 GAM26988.1 - 3e-30 105.2 15.4 1.3e-21 77.0 0.7 5.2 4 1 1 5 5 5 2 RIH domain RIH_assoc PF08454.11 GAM26988.1 - 3e-17 62.3 4.2 3e-17 62.3 4.2 5.0 5 1 0 5 5 5 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 GAM26988.1 - 3.1e-16 59.2 0.1 1e-15 57.5 0.1 1.9 1 1 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RCC1 PF00415.18 GAM26989.1 - 1.2e-73 243.5 3.8 8.1e-15 55.2 0.2 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM26989.1 - 3.6e-40 135.0 25.1 2.3e-10 40.0 1.5 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 GAM26989.1 - 0.11 13.0 1.7 35 4.9 0.0 3.8 4 0 0 4 4 4 0 SUKH-3 immunity protein 7kD_DNA_binding PF02294.18 GAM26989.1 - 0.15 12.1 0.3 13 5.8 0.0 2.8 2 1 0 2 2 2 0 7kD DNA-binding domain Pkinase PF00069.25 GAM26990.1 - 3e-60 203.8 0.2 3.1e-35 121.8 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM26990.1 - 6.4e-35 120.7 0.0 5.6e-17 61.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase DUF3543 PF12063.8 GAM26990.1 - 1.2e-09 38.0 0.1 3.1e-08 33.3 0.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) MIT PF04212.18 GAM26990.1 - 0.00021 21.3 0.1 0.0031 17.5 0.0 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain UBA2_C PF16195.5 GAM26990.1 - 0.013 16.1 1.0 0.023 15.4 1.0 1.3 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus ABC1 PF03109.16 GAM26990.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC1 family SpoU_methylase PF00588.19 GAM26991.1 - 1.5e-14 54.4 0.0 2.2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 GAM26991.1 - 0.0078 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Chorein_N PF12624.7 GAM26992.1 - 0.021 14.9 0.1 0.15 12.1 0.0 2.5 2 0 0 2 2 2 0 N-terminal region of Chorein or VPS13 DUF3014 PF11219.8 GAM26992.1 - 0.039 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) Pkinase_Tyr PF07714.17 GAM26993.1 - 6.1e-45 153.5 0.0 8.2e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 GAM26993.1 - 2.9e-44 151.4 0.0 8.2e-44 149.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain RhoGEF PF00621.20 GAM26993.1 - 1.7e-31 109.9 5.8 5.7e-31 108.2 5.8 2.0 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAM26993.1 - 0.00023 21.6 0.2 0.032 14.7 0.1 2.8 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 GAM26993.1 - 0.00035 19.5 0.0 0.00075 18.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase TrmO PF01980.16 GAM26993.1 - 0.007 16.6 0.2 0.072 13.3 0.0 2.3 1 1 1 2 2 2 1 tRNA-methyltransferase O IQ_SEC7_PH PF16453.5 GAM26993.1 - 0.022 14.7 0.1 0.022 14.7 0.1 2.1 2 0 0 2 2 2 0 PH domain PH_12 PF16457.5 GAM26993.1 - 0.082 13.4 0.2 7.7 7.0 0.2 3.0 2 0 0 2 2 2 0 Pleckstrin homology domain IQ PF00612.27 GAM26993.1 - 0.096 12.5 0.2 0.23 11.3 0.2 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif PX PF00787.24 GAM26995.1 - 2.2e-19 69.5 1.4 2.2e-19 69.5 1.4 1.7 2 0 0 2 2 2 1 PX domain AAA_14 PF13173.6 GAM26995.1 - 0.014 15.4 0.1 0.17 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain Mto2_bdg PF12808.7 GAM26995.1 - 0.11 12.8 7.1 0.17 12.2 0.6 2.3 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region NYD-SP28_assoc PF14775.6 GAM26995.1 - 2.5 8.2 10.6 4.5 7.4 1.8 2.7 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF4201 PF13870.6 GAM26996.1 - 0.58 9.9 45.8 0.16 11.7 14.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) PEMT PF04191.13 GAM26998.1 - 1.5e-29 102.5 1.2 1.5e-29 102.5 1.2 2.1 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 GAM26998.1 - 0.00054 20.0 1.1 0.00081 19.4 0.9 1.4 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 GAM26998.1 - 0.022 15.2 1.4 0.038 14.4 0.1 2.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family zf-CCHC PF00098.23 GAM26999.1 - 4e-21 74.1 45.5 1.4e-05 24.9 3.7 5.3 3 1 2 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 GAM26999.1 - 0.00012 21.7 31.7 0.23 11.2 0.4 5.3 2 1 3 5 5 5 5 Zinc knuckle Sporozoite_P67 PF05642.11 GAM26999.1 - 0.001 17.3 14.0 0.0013 16.9 14.0 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Zip PF02535.22 GAM26999.1 - 0.41 9.8 4.7 0.65 9.1 4.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter zf-CCHC_3 PF13917.6 GAM26999.1 - 0.5 10.4 34.3 0.1 12.6 1.1 4.8 1 1 4 5 5 5 0 Zinc knuckle CTP_transf_1 PF01148.20 GAM27000.1 - 9.6e-70 235.4 26.7 1.2e-69 235.1 26.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Pkinase PF00069.25 GAM27001.1 - 1.3e-44 152.5 0.1 1.3e-23 83.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27001.1 - 1.1e-13 51.0 0.5 4.6e-10 39.2 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase PP2C_2 PF13672.6 GAM27002.1 - 0.0048 16.5 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAM27002.1 - 0.015 15.2 0.0 0.044 13.7 0.0 1.9 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) pRN1_helical PF13010.6 GAM27002.1 - 0.14 12.1 1.5 13 5.7 0.1 2.9 3 0 0 3 3 3 0 Primase helical domain Clat_adaptor_s PF01217.20 GAM27003.1 - 1.7e-50 170.7 6.1 2e-50 170.4 6.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FNIP PF05725.12 GAM27004.1 - 2.2e-18 66.1 12.6 1.4e-13 50.7 0.9 3.2 2 1 1 3 3 3 3 FNIP Repeat DUF3818 PF12825.7 GAM27005.1 - 8.5e-17 61.2 4.2 6.2e-11 41.9 0.7 4.0 4 0 0 4 4 4 2 Domain of unknown function in PX-proteins (DUF3818) p450 PF00067.22 GAM27006.1 - 0.0076 15.0 0.3 0.012 14.4 0.1 1.4 1 1 0 1 1 1 1 Cytochrome P450 SNRNP27 PF08648.12 GAM27006.1 - 0.097 12.8 2.8 0.2 11.8 2.8 1.5 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins CDC45 PF02724.14 GAM27006.1 - 0.1 10.9 5.6 0.11 10.7 5.6 1.0 1 0 0 1 1 1 0 CDC45-like protein SKA1 PF07160.12 GAM27006.1 - 0.13 12.1 10.7 0.16 11.8 10.7 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 GET2 PF08690.10 GAM27006.1 - 0.21 11.2 6.6 0.26 10.9 6.6 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 GAGA_bind PF06217.12 GAM27006.1 - 1 9.6 11.4 1.1 9.4 11.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.22 GAM27006.1 - 3.5 6.8 3.7 3.6 6.7 3.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Ribonucleas_3_3 PF14622.6 GAM27007.1 - 1.1e-06 28.8 1.3 1.4e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease-III-like DUF2722 PF10846.8 GAM27007.1 - 0.011 14.7 12.8 0.017 14.1 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Roughex PF06020.11 GAM27007.1 - 0.034 13.2 2.2 0.056 12.5 2.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein CLN3 PF02487.17 GAM27007.1 - 0.066 12.2 2.5 0.098 11.7 2.5 1.3 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 GAM27007.1 - 0.08 11.7 2.7 0.11 11.3 2.7 1.2 1 0 0 1 1 1 0 Presenilin DUF5352 PF17303.2 GAM27007.1 - 0.14 12.0 5.7 0.39 10.6 3.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5352) Spt20 PF12090.8 GAM27007.1 - 0.15 11.7 20.6 0.34 10.5 20.6 1.6 1 0 0 1 1 1 0 Spt20 family Folliculin PF11704.8 GAM27007.1 - 0.18 11.7 6.2 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Ank_2 PF12796.7 GAM27008.1 - 5.8e-39 132.6 32.4 2.6e-08 34.3 1.8 9.1 1 1 8 10 10 10 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM27008.1 - 4.7e-36 122.4 20.1 6.2e-05 23.2 0.2 14.1 4 3 11 15 15 15 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM27008.1 - 7.4e-34 115.7 19.5 2.5e-06 27.9 0.5 10.8 6 3 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM27008.1 - 1.2e-21 74.4 10.8 0.14 12.8 0.2 14.5 15 1 2 17 17 17 2 Ankyrin repeat DUF5049 PF16468.5 GAM27008.1 - 5.5e-07 29.4 0.3 26 4.8 0.0 7.9 8 2 2 10 10 10 0 Domain of unknown function (DUF5049) Ank PF00023.30 GAM27008.1 - 1.8e-05 25.0 15.7 1.7 9.3 1.8 10.3 7 2 1 8 8 8 1 Ankyrin repeat DUF249 PF03158.13 GAM27008.1 - 2e-05 24.4 11.6 0.054 13.2 0.4 5.7 3 3 1 5 5 5 2 Multigene family 530 protein DUF5644 PF18712.1 GAM27008.1 - 0.0025 17.8 1.1 0.018 15.0 0.2 2.7 3 0 0 3 3 3 1 Family of unknown function (DUF5644) Sushi_2 PF09014.10 GAM27008.1 - 0.008 16.0 3.2 5.9 6.9 0.1 3.9 3 1 1 4 4 4 2 Beta-2-glycoprotein-1 fifth domain PET122 PF05476.11 GAM27008.1 - 0.06 12.6 0.1 13 5.0 0.0 3.7 3 1 1 4 4 4 0 PET122 RTC PF01137.21 GAM27009.1 - 3.1e-58 196.6 0.0 3.5e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 GAM27009.1 - 4.1e-36 123.6 0.0 6.2e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Cyt-b5 PF00173.28 GAM27010.1 - 1.9e-06 27.9 0.1 2.2e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FNIP PF05725.12 GAM27011.1 - 3.3e-62 206.4 27.4 1.9e-12 47.1 0.1 8.3 4 2 5 9 9 9 9 FNIP Repeat DUF3605 PF12239.8 GAM27012.1 - 1.7e-22 80.4 0.0 6.3e-21 75.3 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) TMEM214 PF10151.9 GAM27013.1 - 2e-10 39.8 11.7 2e-10 39.8 11.7 2.7 1 1 0 2 2 2 1 TMEM214, C-terminal, caspase 4 activator BP28CT PF08146.12 GAM27014.1 - 4.6e-39 133.8 4.7 1.5e-38 132.1 2.3 3.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 GAM27014.1 - 5.1e-16 59.1 0.4 5.1e-16 59.1 0.4 7.3 8 1 0 8 8 8 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 GAM27014.1 - 9.4e-06 25.5 10.4 0.019 15.2 0.1 7.6 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 GAM27014.1 - 0.00014 22.2 4.4 14 6.2 0.0 6.5 6 1 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 GAM27014.1 - 0.0039 17.7 12.3 0.05 14.1 0.1 7.7 9 0 0 9 9 9 1 HEAT-like repeat DUF1981 PF09324.10 GAM27014.1 - 0.017 15.0 0.2 0.17 11.7 0.2 3.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) POM121 PF15229.6 GAM27014.1 - 1.5 8.4 6.3 0.29 10.7 0.7 2.3 2 0 0 2 2 2 0 POM121 family Cnd1 PF12717.7 GAM27014.1 - 1.6 8.7 28.0 0.73 9.9 0.1 7.9 7 3 2 9 9 9 0 non-SMC mitotic condensation complex subunit 1 DNA_primase_S PF01896.19 GAM27015.1 - 5e-43 147.2 0.5 8e-43 146.5 0.5 1.3 1 0 0 1 1 1 1 DNA primase small subunit FNIP PF05725.12 GAM27016.1 - 4e-45 151.7 11.4 3.8e-12 46.2 0.3 6.4 3 1 1 6 6 6 5 FNIP Repeat PALP PF00291.25 GAM27017.1 - 1e-79 268.0 1.1 1.2e-79 267.8 1.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FNIP PF05725.12 GAM27018.1 - 2.6e-09 37.1 3.5 0.035 14.3 0.0 6.8 5 3 1 6 6 6 4 FNIP Repeat p450 PF00067.22 GAM27019.1 - 1.2e-105 354.0 3.7 1.3e-105 353.8 3.7 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nop52 PF05997.12 GAM27019.1 - 0.019 14.8 0.5 7.5 6.3 0.0 2.4 3 0 0 3 3 3 0 Nucleolar protein,Nop52 DUF2791 PF10923.8 GAM27019.1 - 0.04 12.8 0.1 0.061 12.2 0.1 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) VIT PF08487.10 GAM27020.1 - 1.4e-32 112.2 2.4 2.9e-31 108.0 1.3 2.6 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 GAM27020.1 - 2.8e-27 95.6 0.0 5.3e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAM27020.1 - 9.8e-10 39.0 0.0 2.6e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM27020.1 - 3.1e-07 31.0 0.0 1.2e-06 29.1 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 GAM27020.1 - 3.2e-07 30.1 0.2 6.9e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain FAD_binding_3 PF01494.19 GAM27021.1 - 8.4e-17 61.4 2.9 1.5e-12 47.5 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM27021.1 - 0.00019 21.6 0.1 0.00052 20.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM27021.1 - 0.001 19.5 0.4 0.23 12.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Orbi_VP7 PF00897.17 GAM27021.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 N2227 PF07942.12 GAM27021.1 - 0.073 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein Pyr_redox_2 PF07992.14 GAM27021.1 - 0.1 11.8 0.6 0.8 8.9 0.1 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PRMT5 PF05185.16 GAM27021.1 - 0.14 12.0 0.0 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase DUF4520 PF15016.6 GAM27021.1 - 0.16 12.0 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) VKG_Carbox PF05090.14 GAM27022.1 - 3e-13 49.4 23.5 1e-12 47.7 13.5 2.2 2 0 0 2 2 2 2 Vitamin K-dependent gamma-carboxylase TPR_6 PF13174.6 GAM27022.1 - 0.093 13.4 0.0 0.4 11.4 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat E1_DerP2_DerF2 PF02221.15 GAM27024.1 - 7.8e-22 78.1 0.2 8.9e-22 78.0 0.2 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 GAM27024.1 - 1.2e-05 25.7 0.2 1.7e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 ML-like domain DUF4625 PF15418.6 GAM27024.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) RasGEF PF00617.19 GAM27027.1 - 2.9e-51 174.2 4.8 5e-51 173.4 4.8 1.4 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.29 GAM27027.1 - 3.1e-16 59.2 0.0 6.5e-09 35.7 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RasGEF_N PF00618.20 GAM27027.1 - 3.7e-13 49.6 0.7 1.1e-12 48.1 0.7 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif GRAM PF02893.20 GAM27027.1 - 1.4e-12 47.5 0.8 8.6e-12 44.9 0.3 2.6 2 0 0 2 2 2 1 GRAM domain CLU PF13236.6 GAM27028.1 - 9.9e-62 208.6 0.0 2.5e-61 207.3 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAM27028.1 - 7.8e-08 32.5 0.0 1.8e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 RhoGEF PF00621.20 GAM27029.1 - 4e-34 118.4 0.8 7.5e-34 117.6 0.8 1.4 1 0 0 1 1 1 1 RhoGEF domain TFIIA PF03153.13 GAM27030.1 - 0.008 16.2 3.9 0.0094 16.0 3.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4214 PF13946.6 GAM27030.1 - 0.017 15.1 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) Med13_C PF06333.12 GAM27030.1 - 0.25 10.6 4.8 0.33 10.2 4.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain TIG PF01833.24 GAM27032.1 - 1.3e-08 34.8 20.7 0.00015 21.8 0.3 4.3 4 0 0 4 4 4 2 IPT/TIG domain EGF_2 PF07974.13 GAM27032.1 - 0.028 14.8 14.3 0.069 13.5 14.3 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 GAM27032.1 - 0.13 12.3 5.0 0.33 11.1 5.0 1.7 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 GAM27032.1 - 9.6 7.0 11.8 29 5.5 11.8 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Thioredoxin_8 PF13905.6 GAM27033.1 - 0.013 15.8 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 GAM27033.1 - 0.13 12.7 0.0 0.17 12.3 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain RhoGAP PF00620.27 GAM27034.1 - 7.1e-26 90.8 0.4 2.7e-25 89.0 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 GAM27034.1 - 4.1e-10 39.8 0.3 2.3e-09 37.4 0.3 2.4 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SMN PF06003.12 GAM27034.1 - 0.52 9.5 5.2 0.86 8.8 4.6 1.6 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) SUIM_assoc PF16619.5 GAM27034.1 - 0.84 9.7 5.6 0.98 9.5 0.7 3.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3270 PF11674.8 GAM27035.1 - 0.0023 18.1 1.1 0.0063 16.7 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3270) DUF5353 PF17304.2 GAM27035.1 - 0.31 10.8 2.8 0.49 10.2 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5353) SKG6 PF08693.10 GAM27036.1 - 0.023 14.1 2.8 0.049 13.0 2.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3827 PF12877.7 GAM27036.1 - 0.26 9.6 0.0 0.38 9.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Guanylate_cyc PF00211.20 GAM27037.1 - 8.1e-50 169.0 1.1 1.3e-49 168.4 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain MHYT PF03707.16 GAM27037.1 - 6.9e-27 93.4 37.7 1.2e-15 57.4 5.1 4.5 4 1 0 4 4 4 3 Bacterial signalling protein N terminal repeat Cation_ATPase_C PF00689.21 GAM27037.1 - 0.0024 17.6 10.5 0.0057 16.4 10.5 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus HNOBA PF07701.14 GAM27037.1 - 0.059 12.8 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Heme NO binding associated Jagunal PF07086.12 GAM27037.1 - 0.1 12.7 11.5 0.21 11.7 10.7 2.0 1 1 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis DUF1218 PF06749.12 GAM27037.1 - 0.27 11.8 6.8 0.27 11.8 4.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) LSM PF01423.22 GAM27038.1 - 2.7e-23 81.4 0.7 3e-23 81.3 0.7 1.0 1 0 0 1 1 1 1 LSM domain SPT16 PF08644.11 GAM27039.1 - 2e-48 164.4 0.8 2e-48 164.4 0.8 4.2 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 GAM27039.1 - 7.3e-48 162.4 0.4 2.4e-47 160.7 0.4 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 GAM27039.1 - 2.6e-29 102.4 0.0 4.1e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 GAM27039.1 - 3.2e-15 56.3 0.1 1.3e-14 54.4 0.1 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like G6PD_C PF02781.16 GAM27039.1 - 0.13 11.5 4.2 0.7 9.0 0.9 2.5 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase, C-terminal domain HECT PF00632.25 GAM27040.1 - 2.9e-80 270.0 0.1 5.1e-80 269.2 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 GAM27040.1 - 1.2e-05 25.1 6.4 3.2 7.9 0.0 5.6 5 1 1 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAM27040.1 - 2.7e-05 24.6 0.2 0.0018 18.7 0.0 3.3 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.22 GAM27040.1 - 0.00042 20.3 1.0 1.4 9.3 0.1 4.4 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 GAM27040.1 - 0.0012 18.9 0.6 14 5.7 0.0 3.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM27040.1 - 0.0075 16.6 0.3 2.8 8.4 0.1 3.3 3 0 0 3 3 3 1 HEAT repeats G-patch PF01585.23 GAM27041.1 - 9.1e-10 38.3 0.1 2.4e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAM27041.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.3 2 1 0 2 2 2 0 G-patch domain SUIM_assoc PF16619.5 GAM27041.1 - 0.81 9.8 30.1 1 9.5 4.4 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PAXX PF15384.6 GAM27042.1 - 0.14 11.9 1.7 0.23 11.1 1.7 1.3 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Mto2_bdg PF12808.7 GAM27042.1 - 2.7 8.4 5.7 1.4 9.3 0.2 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PCRF PF03462.18 GAM27043.1 - 0.021 14.7 8.9 0.23 11.3 0.2 2.0 2 0 0 2 2 2 0 PCRF domain Oxidored_q6 PF01058.22 GAM27043.1 - 0.025 14.4 0.0 0.04 13.8 0.0 1.6 1 1 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit WXG100 PF06013.12 GAM27043.1 - 0.038 14.2 8.9 0.41 10.9 2.2 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DEDD_Tnp_IS110 PF01548.17 GAM27043.1 - 0.093 12.6 1.6 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 Transposase CDPS PF16715.5 GAM27043.1 - 0.3 10.7 6.6 1.7 8.2 1.8 2.1 2 0 0 2 2 2 0 Cyclodipeptide synthase Cbl_N2 PF02761.14 GAM27043.1 - 0.57 10.9 2.0 28 5.5 0.1 2.3 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain Presenilin PF01080.17 GAM27043.1 - 0.64 8.7 4.7 0.92 8.2 4.7 1.2 1 0 0 1 1 1 0 Presenilin LemA PF04011.12 GAM27043.1 - 0.96 9.3 7.6 10 6.0 0.1 2.6 1 1 1 2 2 2 0 LemA family OmpH PF03938.14 GAM27043.1 - 1.3 9.4 19.9 2.7 8.3 13.0 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Aminotran_1_2 PF00155.21 GAM27044.1 - 3.3e-58 197.6 0.0 3.7e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAM27044.1 - 0.00024 19.7 0.0 0.00078 18.1 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAM27044.1 - 0.0012 17.9 0.0 0.0029 16.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 GAM27044.1 - 0.022 13.3 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Aminotran_MocR PF12897.7 GAM27044.1 - 0.085 11.6 0.0 0.59 8.8 0.0 1.9 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase BTB_2 PF02214.22 GAM27045.1 - 3e-17 62.8 0.0 5.3e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAM27045.1 - 0.0025 18.0 0.0 0.0051 17.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain LMBR1 PF04791.16 GAM27047.1 - 1.7e-27 96.5 24.2 2.2e-23 83.0 7.1 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein Asp-Al_Ex PF06826.12 GAM27047.1 - 0.049 13.5 0.2 0.049 13.5 0.2 3.7 4 1 0 4 4 4 0 Predicted Permease Membrane Region Anophelin PF10731.9 GAM27047.1 - 0.13 12.1 0.1 0.69 9.8 0.1 2.3 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Alpha-mann_mid PF09261.11 GAM27049.1 - 2e-17 63.1 0.0 2.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Alpha mannosidase middle domain UDPGP PF01704.18 GAM27050.1 - 1.1e-150 501.9 3.0 1.3e-150 501.6 3.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Gaa1 PF04114.14 GAM27051.1 - 2.7e-99 333.5 8.4 3.7e-99 333.0 8.4 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component ATP-synt_B PF00430.18 GAM27051.1 - 0.12 12.5 1.1 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) APH PF01636.23 GAM27052.1 - 5.7e-20 72.3 0.0 7.5e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM27052.1 - 0.00035 20.2 0.0 0.0018 17.9 0.0 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase Dna2 PF08696.11 GAM27052.1 - 0.15 11.9 0.0 0.33 10.7 0.0 1.5 2 0 0 2 2 2 0 DNA replication factor Dna2 KA1 PF02149.19 GAM27054.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase associated domain 1 DUF1768 PF08719.11 GAM27056.1 - 2.8e-35 121.9 0.0 3.8e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) WD40 PF00400.32 GAM27057.1 - 1.1e-62 206.4 20.3 2.1e-11 44.2 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM27057.1 - 7.8e-23 80.6 1.8 6.4e-06 26.4 0.0 5.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAM27057.1 - 7.4e-13 48.8 0.3 2e-05 24.5 0.0 4.0 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 GAM27057.1 - 2.9e-08 32.9 3.7 0.1 11.2 0.0 5.1 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Frtz PF11768.8 GAM27057.1 - 3.3e-07 29.0 0.1 1.1e-05 24.0 0.0 2.4 2 1 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 GAM27057.1 - 4.3e-07 29.6 0.1 0.0029 17.0 0.0 3.7 3 2 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 GAM27057.1 - 6e-05 22.2 0.1 0.33 9.9 0.0 3.7 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAM27057.1 - 6.4e-05 21.6 0.8 0.68 8.4 0.0 3.1 1 1 2 3 3 3 3 Cytochrome D1 heme domain VID27 PF08553.10 GAM27057.1 - 6.6e-05 22.1 0.0 0.45 9.5 0.0 2.8 1 1 2 3 3 3 2 VID27 C-terminal WD40-like domain PD40 PF07676.12 GAM27057.1 - 0.00035 20.4 3.8 1.1 9.3 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 GAM27057.1 - 0.0013 17.9 1.3 0.15 11.1 0.1 2.9 1 1 0 2 2 2 1 Coatomer WD associated region PALB2_WD40 PF16756.5 GAM27057.1 - 0.0075 15.2 0.3 4.9 6.0 0.0 3.6 1 1 3 4 4 4 1 Partner and localizer of BRCA2 WD40 domain DUF4221 PF13970.6 GAM27057.1 - 0.018 14.6 0.4 1.5 8.3 0.0 3.2 2 1 3 5 5 5 0 Domain of unknown function (DUF4221) Kelch_6 PF13964.6 GAM27057.1 - 0.056 13.8 1.4 3.2 8.2 0.1 3.9 4 0 0 4 4 4 0 Kelch motif SBD PF17882.1 GAM27057.1 - 0.095 12.5 0.2 1 9.2 0.1 2.6 2 1 1 3 3 3 0 OAA-family lectin sugar binding domain Hira PF07569.11 GAM27057.1 - 0.15 11.8 1.7 7.9 6.1 0.1 3.5 3 1 2 5 5 5 0 TUP1-like enhancer of split Sas10_Utp3 PF04000.15 GAM27058.1 - 9.6e-13 48.6 0.6 1.2e-12 48.2 0.0 1.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Fungal_trans_2 PF11951.8 GAM27058.1 - 0.085 11.7 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain zf-4CXXC_R1 PF10497.9 GAM27060.1 - 5.8e-10 39.3 17.5 1.1e-09 38.4 17.5 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PhoPQ_related PF10142.9 GAM27061.1 - 4.9e-66 222.9 0.0 6e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DUF4950 PF16308.5 GAM27061.1 - 0.053 13.5 0.1 0.09 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4950) TPR_1 PF00515.28 GAM27062.1 - 8.4e-51 167.8 27.6 2e-07 30.6 0.5 9.3 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAM27062.1 - 5.6e-44 144.7 22.9 3.4e-06 26.7 0.4 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 GAM27062.1 - 1.3e-31 108.3 6.3 1e-15 57.4 0.7 2.7 2 0 0 2 2 2 2 STI1 domain TPR_8 PF13181.6 GAM27062.1 - 1.4e-27 93.5 18.5 0.001 19.1 0.2 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAM27062.1 - 2.1e-27 94.5 16.4 6e-08 32.3 0.5 7.1 7 2 1 8 8 8 5 TPR repeat TPR_12 PF13424.6 GAM27062.1 - 7.9e-23 80.6 12.5 1.9e-07 31.2 1.2 7.3 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 GAM27062.1 - 5.4e-20 71.8 2.3 9.4e-05 23.0 0.1 5.7 4 2 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM27062.1 - 8.1e-19 66.7 1.1 0.0036 18.0 0.1 8.0 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM27062.1 - 3e-17 62.9 11.2 1e-06 29.1 0.7 6.5 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM27062.1 - 5.8e-17 60.8 12.2 0.0016 18.7 0.2 7.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAM27062.1 - 8.1e-16 56.8 7.5 0.63 10.2 0.0 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM27062.1 - 3.4e-10 39.8 8.6 0.0051 16.9 0.0 6.2 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 GAM27062.1 - 4.3e-07 30.0 0.1 1.4 9.1 0.0 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAM27062.1 - 3.1e-06 26.8 17.2 1.1 9.3 0.2 8.6 10 0 0 10 10 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM27062.1 - 2.7e-05 24.3 11.3 0.017 15.3 1.4 4.1 3 2 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAM27062.1 - 0.00053 20.4 10.0 25 5.8 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF3856 PF12968.7 GAM27062.1 - 0.00064 19.8 6.7 7.3 6.6 0.1 5.6 3 3 1 5 5 5 0 Domain of Unknown Function (DUF3856) DUF737 PF05300.11 GAM27062.1 - 0.00089 19.7 1.8 0.00089 19.7 1.8 3.3 2 1 0 3 3 3 1 Protein of unknown function (DUF737) TPR_20 PF14561.6 GAM27062.1 - 0.0017 18.7 4.1 4.5 7.7 0.2 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF627 PF04781.12 GAM27062.1 - 0.0078 16.2 0.9 24 5.0 0.0 4.4 3 1 0 3 3 3 0 Protein of unknown function (DUF627) MIT PF04212.18 GAM27062.1 - 0.023 14.7 22.0 9.1 6.4 0.1 7.1 5 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 GAM27062.1 - 0.048 12.7 3.4 10 5.0 0.1 3.1 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) SMBP PF16785.5 GAM27062.1 - 0.083 13.1 7.4 1.8 8.8 0.3 4.0 4 0 0 4 4 4 0 Small metal-binding protein SHNi-TPR PF10516.9 GAM27062.1 - 0.18 11.3 7.0 71 3.0 0.0 5.9 8 0 0 8 8 7 0 SHNi-TPR Alkyl_sulf_dimr PF14863.6 GAM27062.1 - 0.78 10.2 12.5 0.94 9.9 0.5 4.4 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation TOM20_plant PF06552.12 GAM27062.1 - 1.1 8.9 11.3 6.1 6.5 0.1 4.9 3 1 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 DUF357 PF04010.13 GAM27062.1 - 1.2 9.3 4.3 1.2 9.2 0.2 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF357) DUF2225 PF09986.9 GAM27062.1 - 2.9 7.6 14.2 0.8 9.4 5.2 3.2 2 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) CH PF00307.31 GAM27064.1 - 2.5e-61 204.6 2.0 7.5e-18 64.7 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 GAM27064.1 - 3.2e-10 40.3 0.2 8e-10 39.0 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 GAM27064.1 - 4e-10 38.5 1.5 5.2e-05 22.5 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 GAM27064.1 - 5.4e-09 35.8 0.5 0.0032 17.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair CAMSAP_CH PF11971.8 GAM27064.1 - 1.6e-08 34.3 0.3 0.43 10.4 0.1 4.4 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_6 PF13405.6 GAM27064.1 - 2.6e-08 33.2 1.4 0.0052 16.6 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 GAM27064.1 - 2.8e-07 29.7 1.4 0.0017 17.8 0.1 2.8 3 0 0 3 3 3 2 EF hand CH_2 PF06294.11 GAM27064.1 - 0.00052 20.1 0.0 3.2 8.0 0.0 3.5 3 0 0 3 3 3 2 CH-like domain in sperm protein Dockerin_1 PF00404.18 GAM27064.1 - 0.021 15.0 0.1 0.056 13.7 0.1 1.8 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_9 PF14658.6 GAM27064.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain DDE_Tnp_4 PF13359.6 GAM27066.1 - 3.6e-18 65.7 0.0 7.5e-17 61.4 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM27066.1 - 4.7e-08 32.9 0.0 7.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain TPR_19 PF14559.6 GAM27068.1 - 0.02 15.4 0.1 7.3 7.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 GAM27068.1 - 0.025 14.8 0.1 2.3 8.7 0.0 3.2 3 0 0 3 3 3 0 PPR repeat PPR_2 PF13041.6 GAM27068.1 - 0.032 14.4 0.0 9.1 6.6 0.0 3.7 3 0 0 3 3 3 0 PPR repeat family TPR_5 PF12688.7 GAM27068.1 - 0.052 13.8 0.0 24 5.2 0.0 3.3 2 1 1 3 3 3 0 Tetratrico peptide repeat TPR_4 PF07721.14 GAM27068.1 - 0.066 13.9 1.9 29 5.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PI3Ka PF00613.20 GAM27069.1 - 4.6e-51 172.8 2.2 4.6e-51 172.8 2.2 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 GAM27069.1 - 5.8e-46 157.3 0.8 5.3e-45 154.2 0.1 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 GAM27069.1 - 4.2e-13 49.4 0.1 1.2e-12 47.9 0.1 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 GAM27069.1 - 0.00043 19.7 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) DUF3450 PF11932.8 GAM27069.1 - 0.18 11.1 14.8 0.35 10.1 3.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ACCA PF03255.14 GAM27069.1 - 2.8 7.8 9.2 6.5 6.6 1.5 3.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit dCMP_cyt_deam_1 PF00383.23 GAM27070.1 - 7.4e-13 48.3 0.0 1.4e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAM27070.1 - 3.8e-05 23.5 0.6 5.1e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 MafB19-like deaminase TMEM189_B_dmain PF10520.9 GAM27070.1 - 0.33 11.1 2.8 0.95 9.6 2.8 2.0 1 1 0 1 1 1 0 B domain of TMEM189, localisation domain Nop14 PF04147.12 GAM27072.1 - 0.093 10.9 19.9 0.094 10.9 19.9 1.0 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 GAM27072.1 - 0.63 8.8 16.2 0.66 8.7 16.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RP-C_C PF11800.8 GAM27072.1 - 0.63 10.1 8.5 0.67 10.0 8.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF913 PF06025.12 GAM27072.1 - 0.69 8.8 9.1 0.72 8.8 9.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) eIF-3c_N PF05470.12 GAM27072.1 - 1.3 7.2 15.5 1.4 7.2 15.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mitofilin PF09731.9 GAM27072.1 - 1.4 7.6 20.9 1.4 7.6 20.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PPL5 PF18168.1 GAM27072.1 - 1.7 7.9 13.8 1.9 7.7 13.8 1.0 1 0 0 1 1 1 0 Prim-pol family 5 GAGA_bind PF06217.12 GAM27072.1 - 3.1 8.0 13.4 3.4 7.9 13.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family TP53IP5 PF15331.6 GAM27072.1 - 3.4 7.7 16.0 3.5 7.7 16.0 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Hid1 PF12722.7 GAM27072.1 - 4.5 5.3 13.1 4.4 5.3 13.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 GAM27072.1 - 5.4 5.7 16.1 5.7 5.6 16.1 1.0 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 GAM27072.1 - 7.4 5.5 14.3 7.3 5.5 14.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 GAM27072.1 - 8.9 4.5 22.4 9.9 4.3 22.4 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 GAM27072.1 - 9.4 4.9 16.8 9.5 4.9 16.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Utp12 PF04003.12 GAM27073.1 - 8.3e-13 48.6 2.0 1.6e-12 47.6 2.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 GAM27073.1 - 5e-06 27.1 0.7 1.1 10.3 0.3 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM27073.1 - 1.6e-05 25.1 0.9 0.041 14.2 0.1 4.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DSPc PF00782.20 GAM27074.1 - 7.7e-29 100.2 0.1 1.2e-28 99.5 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM27074.1 - 0.0029 17.2 0.0 0.0047 16.5 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase HeH PF12949.7 GAM27075.1 - 1.1e-06 28.3 0.1 2.6e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 HeH/LEM domain PIP5K PF01504.18 GAM27075.1 - 0.24 10.6 10.6 0.41 9.8 10.6 1.6 1 1 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase FNIP PF05725.12 GAM27076.1 - 1.2e-101 332.6 72.6 4.6e-13 49.1 0.1 12.2 3 2 16 19 19 19 18 FNIP Repeat DUF1601 PF07671.11 GAM27076.1 - 0.22 11.4 1.6 31 4.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1601) zf-RING_2 PF13639.6 GAM27077.1 - 3.7e-06 27.2 8.8 1.1e-05 25.7 8.8 1.9 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 GAM27077.1 - 5e-06 26.6 6.2 1.5e-05 25.0 6.2 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 GAM27077.1 - 0.0005 20.1 5.1 0.0018 18.3 5.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HEAT PF02985.22 GAM27077.1 - 0.0045 17.1 0.0 0.57 10.6 0.0 3.6 2 0 0 2 2 2 1 HEAT repeat zf-rbx1 PF12678.7 GAM27077.1 - 0.005 17.1 9.9 0.017 15.4 9.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain C1_1 PF00130.22 GAM27077.1 - 0.0069 16.2 4.2 0.0069 16.2 4.2 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 GAM27077.1 - 0.01 15.7 9.2 0.029 14.2 9.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HEAT_2 PF13646.6 GAM27077.1 - 0.017 15.5 0.0 9.4 6.7 0.0 4.3 3 0 0 3 3 3 0 HEAT repeats zf-C3HC4 PF00097.25 GAM27077.1 - 0.034 14.0 9.9 0.1 12.5 9.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 GAM27077.1 - 0.065 13.6 7.4 0.15 12.4 7.4 1.7 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 GAM27077.1 - 0.11 12.1 4.8 0.27 10.9 4.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 GAM27077.1 - 0.12 12.5 2.5 0.36 11.0 2.5 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger Coronavirus_5 PF05528.11 GAM27077.1 - 0.19 11.7 2.7 8 6.5 0.3 2.9 2 0 0 2 2 2 0 Coronavirus gene 5 protein RINGv PF12906.7 GAM27077.1 - 0.2 11.8 5.8 0.55 10.4 5.8 1.8 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 GAM27077.1 - 1.2 9.1 6.3 2.7 7.9 6.3 1.7 1 0 0 1 1 1 0 PHD-finger zf-C3Hc3H PF13891.6 GAM27078.1 - 8.7e-09 35.6 6.5 1.9e-08 34.6 6.5 1.6 1 0 0 1 1 1 1 Potential DNA-binding domain zf-primase PF09329.11 GAM27078.1 - 0.00031 20.5 1.6 0.00031 20.5 1.6 2.7 3 1 0 3 3 3 1 Primase zinc finger Pox_G9-A16 PF03003.16 GAM27078.1 - 0.044 13.5 2.0 0.1 12.3 2.0 1.6 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 INTS2 PF14750.6 GAM27079.1 - 2.1e-149 499.1 26.6 1.6e-145 486.3 23.5 2.4 2 1 0 2 2 2 2 Integrator complex subunit 2 FNIP PF05725.12 GAM27080.1 - 3.4e-22 78.3 17.8 5.2e-05 23.3 0.0 7.6 7 2 0 7 7 7 5 FNIP Repeat Cyclin_N PF00134.23 GAM27081.1 - 6.8e-08 32.3 1.1 1.6e-07 31.1 0.8 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain RNase_HII PF01351.18 GAM27082.1 - 1.7e-24 86.7 0.0 2.2e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII adh_short PF00106.25 GAM27083.1 - 2.3e-29 102.2 0.0 3.4e-28 98.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM27083.1 - 2.4e-14 53.5 0.0 3.2e-13 49.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM27083.1 - 2.8e-07 30.6 0.0 4.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM27083.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Rad10 PF03834.14 GAM27084.1 - 4.5e-22 78.2 0.1 9.9e-22 77.1 0.0 1.6 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 GAM27084.1 - 0.00055 20.5 0.0 0.0017 18.9 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain PI3K_1B_p101 PF10486.9 GAM27084.1 - 0.033 12.0 4.9 0.045 11.5 4.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DMAP1 PF05499.12 GAM27084.1 - 0.2 11.5 1.3 0.5 10.2 1.3 1.6 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) SPX PF03105.19 GAM27084.1 - 0.22 11.4 11.6 0.44 10.4 11.6 1.5 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 GAM27084.1 - 1 7.9 7.7 1.4 7.4 7.7 1.2 1 0 0 1 1 1 0 Macoilin family FAM199X PF15814.5 GAM27084.1 - 4.4 6.3 13.1 26 3.7 0.1 2.4 2 0 0 2 2 2 0 Protein family FAM199X CEND1 PF15677.5 GAM27084.1 - 4.7 7.8 11.7 1.6 9.2 8.5 1.9 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 CCDC24 PF15669.5 GAM27084.1 - 5.1 6.9 10.2 1.9 8.3 7.3 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Zip PF02535.22 GAM27086.1 - 0.001 18.4 0.1 0.0041 16.4 0.1 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter ETRAMP PF09716.10 GAM27086.1 - 4.5 7.4 8.0 29 4.8 8.0 2.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ank_2 PF12796.7 GAM27087.1 - 1.9e-09 38.0 15.9 0.027 15.1 0.1 6.8 4 3 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM27087.1 - 0.00032 21.2 12.6 2.5 8.8 0.2 6.7 4 2 0 5 5 5 3 Ankyrin repeats (many copies) SCAMP PF04144.13 GAM27088.1 - 5.5e-28 98.4 14.7 7.3e-28 98.0 14.7 1.0 1 0 0 1 1 1 1 SCAMP family HDV_ag PF01517.18 GAM27088.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen DUF4190 PF13828.6 GAM27088.1 - 1.3 8.8 8.3 3.6 7.4 3.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4190) COPI_assoc PF08507.10 GAM27088.1 - 1.9 8.6 13.3 0.41 10.7 9.9 1.6 2 0 0 2 2 2 0 COPI associated protein F-box-like PF12937.7 GAM27089.1 - 1.3e-10 41.0 0.2 3.9e-10 39.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM27089.1 - 8.5e-07 28.7 1.2 1.9e-06 27.6 0.6 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 GAM27089.1 - 0.00088 19.1 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 F-box F-box-like_2 PF13013.6 GAM27089.1 - 0.004 17.1 0.1 0.02 14.8 0.0 2.2 3 0 0 3 3 3 1 F-box-like domain BUD22 PF09073.10 GAM27089.1 - 0.028 13.8 5.6 0.04 13.3 5.6 1.1 1 0 0 1 1 1 0 BUD22 CDC27 PF09507.10 GAM27089.1 - 0.037 13.4 3.4 0.055 12.9 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mpp10 PF04006.12 GAM27089.1 - 0.037 12.5 11.8 0.052 12.0 11.8 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 GAM27089.1 - 0.043 12.1 6.5 0.059 11.7 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Osteopontin PF00865.18 GAM27089.1 - 0.49 9.8 17.9 0.79 9.2 17.9 1.2 1 0 0 1 1 1 0 Osteopontin DNA_pol_phi PF04931.13 GAM27089.1 - 0.66 8.0 14.1 1.2 7.2 14.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 GAM27089.1 - 2.8 8.0 11.4 4.5 7.3 11.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein bZIP_1 PF00170.21 GAM27090.1 - 7.9e-12 45.1 11.4 7.9e-12 45.1 11.4 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAM27090.1 - 5.7e-07 29.5 9.1 5.7e-07 29.5 9.1 3.9 3 2 1 4 4 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 GAM27090.1 - 0.0018 18.7 7.7 0.0018 18.7 7.7 3.1 3 0 0 3 3 3 1 bZIP Maf transcription factor HALZ PF02183.18 GAM27090.1 - 0.0033 17.6 0.3 0.0033 17.6 0.3 2.4 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF2205 PF10224.9 GAM27090.1 - 0.0035 17.3 1.8 0.0035 17.3 1.8 2.4 2 0 0 2 2 1 1 Short coiled-coil protein Cwf_Cwc_15 PF04889.12 GAM27090.1 - 0.15 11.7 35.3 0.39 10.4 35.3 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ndc1_Nup PF09531.10 GAM27090.1 - 0.29 9.8 11.5 0.33 9.6 11.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1664 PF07889.12 GAM27090.1 - 0.83 9.7 11.2 1.5 8.9 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.19 GAM27090.1 - 2.4 7.9 22.7 59 3.3 22.8 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family FlaC_arch PF05377.11 GAM27090.1 - 5 7.6 9.4 2.4 8.6 1.6 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 GAM27090.1 - 6.6 7.4 12.8 0.7 10.6 1.0 2.5 2 0 0 2 2 2 0 Initiation control protein YabA zf-CCHC PF00098.23 GAM27091.1 - 1.9e-33 113.0 42.5 7.2e-09 35.3 4.0 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 GAM27091.1 - 5.2e-08 32.5 23.1 0.27 11.0 1.1 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.6 GAM27091.1 - 5.2e-06 26.2 1.5 5.2e-06 26.2 1.5 5.5 5 1 0 5 5 5 3 Zinc knuckle zf-CCHC_5 PF14787.6 GAM27091.1 - 0.00068 19.3 32.7 0.27 11.0 0.9 5.0 4 1 1 5 5 5 4 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 GAM27091.1 - 0.0019 18.1 33.3 0.24 11.4 1.0 5.0 2 1 3 5 5 5 4 Zinc knuckle zf-CCHC_6 PF15288.6 GAM27091.1 - 0.0098 15.7 2.3 0.0098 15.7 2.3 4.6 4 1 1 5 5 5 3 Zinc knuckle Rpr2 PF04032.16 GAM27092.1 - 2.5e-11 43.7 2.3 2.5e-11 43.7 2.3 3.6 4 2 0 4 4 4 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain BAR PF03114.18 GAM27093.1 - 1.6e-20 73.8 10.7 6.7e-20 71.7 10.7 1.8 1 1 0 1 1 1 1 BAR domain SH3_9 PF14604.6 GAM27093.1 - 2e-15 56.4 0.0 5.6e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM27093.1 - 8.2e-13 47.7 0.0 2e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM27093.1 - 5.8e-09 35.5 0.0 1.3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Synaptonemal_3 PF15191.6 GAM27093.1 - 0.0032 17.2 3.3 0.0032 17.2 1.4 1.9 2 0 0 2 2 2 1 Synaptonemal complex central element protein 3 LOH1CR12 PF10158.9 GAM27093.1 - 0.02 14.9 1.1 0.048 13.7 0.8 1.8 1 1 0 1 1 1 0 Tumour suppressor protein DUF3156 PF11354.8 GAM27093.1 - 0.12 12.3 0.4 0.29 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3156) Fmp27_WPPW PF10359.9 GAM27093.1 - 0.15 10.9 5.8 0.22 10.3 5.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain zf-C4H2 PF10146.9 GAM27093.1 - 0.22 11.8 4.9 1.2 9.4 4.9 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein Bacillus_HBL PF05791.11 GAM27093.1 - 0.39 10.5 5.5 0.11 12.4 1.6 2.1 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FapA PF03961.13 GAM27093.1 - 0.87 8.1 6.8 0.48 9.0 1.5 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A RQC PF09382.10 GAM27094.1 - 3.9e-23 81.4 0.1 1.1e-22 80.0 0.1 1.8 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 GAM27094.1 - 4.8e-19 68.8 0.2 6.8e-18 65.0 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.23 GAM27094.1 - 6.1e-14 51.8 0.1 1.3e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 HRDC domain DEAD PF00270.29 GAM27094.1 - 1.6e-13 50.8 0.0 4.5e-12 46.1 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 GAM27094.1 - 4.5e-09 36.9 0.6 1.4e-08 35.3 0.6 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 GAM27094.1 - 0.026 14.5 0.2 0.21 11.6 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF3439 PF11921.8 GAM27094.1 - 0.078 12.9 3.5 0.2 11.6 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4269 PF14091.6 GAM27094.1 - 0.11 12.7 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) SSP160 PF06933.11 GAM27094.1 - 2.9 6.0 8.4 4.6 5.3 8.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CobU PF02283.16 GAM27095.1 - 0.019 14.5 0.6 0.19 11.3 0.0 2.5 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Atx10homo_assoc PF09759.9 GAM27095.1 - 0.092 12.8 1.2 33 4.6 0.0 3.5 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 GAM27095.1 - 0.17 12.0 7.6 10 6.3 0.0 5.9 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat SdrD_B PF17210.3 GAM27096.1 - 5.3e-92 303.6 86.1 2.3e-11 43.9 0.2 14.9 13 1 2 15 15 15 12 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM27096.1 - 1.5e-26 92.5 89.0 0.00025 21.3 0.1 16.3 13 4 2 15 15 15 11 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 GAM27096.1 - 1.2e-23 83.6 0.0 0.64 10.1 0.0 12.2 12 0 0 12 12 12 4 Protein of unknown function (DUF2012) FlgD_ig PF13860.6 GAM27096.1 - 1e-12 47.7 38.7 0.044 13.6 0.1 14.3 12 3 2 14 14 14 6 FlgD Ig-like domain CarbopepD_reg_2 PF13715.6 GAM27096.1 - 5.5e-07 29.5 26.9 0.087 12.8 0.0 11.4 11 2 2 13 13 13 2 CarboxypepD_reg-like domain SpaA PF17802.1 GAM27096.1 - 0.00021 21.6 74.0 0.2 12.0 0.0 15.1 11 1 1 12 12 12 4 Prealbumin-like fold domain Y_Y_Y PF07495.13 GAM27096.1 - 0.00041 20.2 13.3 11 6.1 0.1 9.4 12 0 0 12 12 12 1 Y_Y_Y domain Bac_A_amyl_C PF18612.1 GAM27096.1 - 0.00059 19.5 0.6 61 3.5 0.0 6.0 6 0 0 6 6 6 0 Bacterial Alpha amylase C-terminal domain LVIVD PF08309.11 GAM27096.1 - 0.0096 15.2 11.1 9.8 5.6 0.0 6.4 7 0 0 7 7 7 1 LVIVD repeat Ground-like PF04155.18 GAM27096.1 - 0.095 13.4 7.6 12 6.7 0.0 5.5 5 0 0 5 5 5 0 Ground-like domain WW PF00397.26 GAM27097.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 WW domain TPR_1 PF00515.28 GAM27097.1 - 0.028 14.2 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAM27097.1 - 0.043 13.9 0.0 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3391 PF11871.8 GAM27097.1 - 1.3 9.6 3.0 2.1 8.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) DSPc PF00782.20 GAM27099.1 - 2.6e-07 30.5 0.1 7.6e-07 29.0 0.1 1.7 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM27099.1 - 2.6e-05 23.9 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAM27099.1 - 0.00033 20.7 0.3 0.00079 19.5 0.1 1.5 1 1 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 GAM27099.1 - 0.018 15.1 0.0 0.047 13.8 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate PTEN_C2 PF10409.9 GAM27100.1 - 5.6e-07 29.4 0.0 6.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DNA_pol_B_palm PF14792.6 GAM27101.1 - 2.8e-30 104.9 0.1 5.5e-30 103.9 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 GAM27101.1 - 1.1e-22 79.9 0.1 2.1e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 GAM27101.1 - 7.2e-17 61.0 0.2 1.7e-16 59.7 0.2 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 GAM27101.1 - 1.7e-15 57.1 0.3 1.6e-14 54.0 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 GAM27101.1 - 1.5e-05 25.5 0.5 0.0032 18.0 0.2 2.6 1 1 2 3 3 3 3 Helix-hairpin-helix domain BCDHK_Adom3 PF10436.9 GAM27101.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase CAMSAP_CKK PF08683.11 GAM27101.1 - 0.13 12.4 0.0 7.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated FNIP PF05725.12 GAM27103.1 - 4.8e-15 55.5 24.6 5e-06 26.6 0.4 7.0 6 1 1 7 7 7 5 FNIP Repeat RTX_C PF08339.10 GAM27103.1 - 0.12 12.4 2.3 4.3 7.4 0.1 2.3 2 0 0 2 2 2 0 RTX C-terminal domain Mannosyl_trans2 PF04188.13 GAM27104.1 - 5e-75 253.5 37.2 1.9e-42 146.1 12.2 2.1 2 0 0 2 2 2 2 Mannosyltransferase (PIG-V) TIG PF01833.24 GAM27105.1 - 3.4e-16 59.1 41.0 1.5e-08 34.6 1.6 6.1 5 1 1 6 6 6 5 IPT/TIG domain MHB PF16525.5 GAM27105.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Haemophore, haem-binding FNIP PF05725.12 GAM27106.1 - 2.9e-78 257.8 23.6 4.8e-15 55.4 0.9 8.1 5 2 0 8 8 8 7 FNIP Repeat FNIP PF05725.12 GAM27107.1 - 3e-45 152.1 4.2 3.8e-13 49.4 0.0 5.6 3 2 1 6 6 6 5 FNIP Repeat NSP16 PF06460.12 GAM27107.1 - 0.00096 18.3 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Coronavirus NSP16 Glyco_transf_10 PF00852.19 GAM27108.1 - 4.5e-36 124.2 0.6 7.7e-36 123.4 0.4 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 GAM27108.1 - 3.8e-07 30.5 0.2 9.8e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal Aerolysin PF01117.20 GAM27108.1 - 0.027 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Aerolysin toxin Arf PF00025.21 GAM27109.1 - 2.5e-59 199.7 0.0 3.6e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM27109.1 - 6.5e-14 52.2 0.0 1.1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM27109.1 - 1.1e-11 44.6 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAM27109.1 - 7.8e-11 41.7 0.9 2.6e-07 30.1 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GAM27109.1 - 1.3e-10 41.0 0.0 2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAM27109.1 - 9e-08 31.8 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM27109.1 - 1.4e-05 25.2 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.14 GAM27109.1 - 0.00086 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 GAM27109.1 - 0.088 12.4 0.1 1 8.9 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ACT PF01842.25 GAM27109.1 - 0.11 12.3 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 ACT domain AAA_33 PF13671.6 GAM27109.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM27109.1 - 0.27 11.7 1.2 0.29 11.7 0.1 1.8 2 1 0 2 2 2 0 ABC transporter RhoGAP PF00620.27 GAM27110.1 - 8.3e-39 132.9 0.6 2e-38 131.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LRR_6 PF13516.6 GAM27110.1 - 3.1e-10 39.3 27.3 0.0051 16.8 0.3 8.4 8 0 0 8 8 8 4 Leucine Rich repeat Carm_PH PF17888.1 GAM27110.1 - 3.4e-07 30.5 0.7 6.7e-07 29.6 0.1 1.8 2 0 0 2 2 2 1 Carmil pleckstrin homology domain LRR_4 PF12799.7 GAM27110.1 - 0.00024 21.4 25.4 1.2 9.6 0.1 6.7 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM27110.1 - 0.028 14.9 12.1 1 10.1 0.1 7.0 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 GAM27110.1 - 0.14 11.9 13.2 9.5 6.1 0.3 6.1 4 1 1 5 5 5 0 Leucine rich repeat S4 PF01479.25 GAM27112.1 - 1.3e-10 40.8 0.3 4e-10 39.2 0.3 1.9 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 GAM27112.1 - 2.8e-05 24.9 0.5 6.1e-05 23.9 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Peptidase_M66 PF10462.9 GAM27113.1 - 2.8e-56 190.7 0.0 4.1e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 GAM27113.1 - 0.034 14.7 0.0 0.14 12.7 0.0 2.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like TagA PF12561.8 GAM27113.1 - 0.096 13.1 0.1 0.24 11.8 0.1 1.7 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain fn3 PF00041.21 GAM27115.1 - 8.6e-07 29.2 13.1 0.0055 17.0 0.2 4.8 4 1 0 4 4 4 3 Fibronectin type III domain EGF_2 PF07974.13 GAM27115.1 - 0.01 16.2 14.4 0.047 14.1 14.4 2.3 1 0 0 1 1 1 0 EGF-like domain Pur_ac_phosph_N PF16656.5 GAM27115.1 - 0.024 15.2 9.5 0.15 12.7 0.2 4.1 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain FPL PF09758.9 GAM27116.1 - 1.1e-60 203.9 11.5 1.1e-60 203.9 11.5 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein NRDE-2 PF08424.10 GAM27116.1 - 0.17 11.0 1.1 15 4.6 0.1 3.2 3 0 0 3 3 3 0 NRDE-2, necessary for RNA interference DUF3439 PF11921.8 GAM27116.1 - 0.24 11.4 11.0 0.7 9.9 11.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RRM_1 PF00076.22 GAM27117.1 - 1.2e-26 92.3 3.6 1.1e-14 54.0 0.2 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM27117.1 - 3.8e-06 26.9 0.1 0.015 15.4 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM PF05172.13 GAM27117.1 - 0.00022 21.1 0.1 1 9.4 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif BRAP2 PF07576.12 GAM27117.1 - 0.028 14.6 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 Nup35_RRM_2 PF14605.6 GAM27117.1 - 0.31 11.1 1.0 19 5.4 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF202 PF02656.15 GAM27118.1 - 3.4e-08 33.8 5.9 3.4e-08 33.8 5.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3439 PF11921.8 GAM27118.1 - 0.11 12.5 2.0 0.2 11.6 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2207 PF09972.9 GAM27118.1 - 0.16 10.7 0.0 0.16 10.7 0.0 3.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF966 PF06136.13 GAM27118.1 - 0.38 10.4 26.7 0.59 9.8 26.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mucin PF01456.17 GAM27118.1 - 0.38 10.7 10.2 0.075 13.0 2.5 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Dapper PF15268.6 GAM27118.1 - 5.8 5.6 32.5 7.3 5.3 32.5 1.1 1 0 0 1 1 1 0 Dapper YL1 PF05764.13 GAM27118.1 - 6.5 6.8 71.1 0.15 12.2 53.8 2.4 1 1 1 2 2 2 0 YL1 nuclear protein RasGAP PF00616.19 GAM27119.1 - 9e-31 107.2 0.0 9e-31 107.2 0.0 2.9 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 GAM27119.1 - 3e-16 59.8 3.2 3e-16 59.8 3.2 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 GAM27119.1 - 1.7e-13 50.6 2.0 3.4e-13 49.6 2.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Myosin_TH1 PF06017.13 GAM27119.1 - 3.5e-06 26.8 4.7 0.026 14.2 1.5 2.4 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding Ras PF00071.22 GAM27120.1 - 8.6e-58 194.5 0.5 1e-57 194.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM27120.1 - 2.7e-35 121.2 0.1 4.4e-35 120.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM27120.1 - 3.7e-16 59.1 0.1 4.5e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM27120.1 - 8.8e-09 35.0 0.6 1.1e-08 34.7 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM27120.1 - 3.4e-07 30.3 0.1 1.2e-06 28.6 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM27120.1 - 8.8e-06 25.4 0.2 2.5e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAM27120.1 - 4e-05 23.2 0.2 0.00017 21.2 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAM27120.1 - 0.00033 20.6 0.3 0.39 10.6 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 GAM27120.1 - 0.00048 19.6 0.1 0.00064 19.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit CPT PF07931.12 GAM27120.1 - 0.07 13.0 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 GAM27120.1 - 0.1 12.0 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Vma12 PF11712.8 GAM27121.1 - 6.6e-10 39.2 0.2 1.3e-09 38.2 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase LptF_LptG PF03739.14 GAM27121.1 - 0.01 14.7 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF3021 PF11457.8 GAM27121.1 - 0.022 15.1 0.3 0.036 14.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) MFS_2 PF13347.6 GAM27121.1 - 0.034 12.7 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein PIG-H PF10181.9 GAM27122.1 - 0.15 11.9 2.3 0.23 11.4 0.3 2.0 2 0 0 2 2 2 0 GPI-GlcNAc transferase complex, PIG-H component DUF872 PF05915.12 GAM27122.1 - 1.3 9.2 6.1 0.28 11.4 0.3 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Strabismus PF06638.11 GAM27122.1 - 6.9 5.2 7.1 8 5.0 7.1 1.1 1 0 0 1 1 1 0 Strabismus protein TFIIB PF00382.19 GAM27124.1 - 2.6e-42 142.7 0.4 2.6e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 GAM27124.1 - 3.2e-15 55.4 2.4 5.3e-15 54.7 2.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 GAM27124.1 - 1.7e-05 24.9 0.5 0.12 12.4 0.2 2.3 1 1 1 2 2 2 2 Cyclin, C-terminal domain HTH_Tnp_ISL3 PF13542.6 GAM27124.1 - 0.0029 17.0 0.0 0.0076 15.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 GAM27124.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 HTH domain RB_B PF01857.20 GAM27124.1 - 0.017 15.2 0.1 0.085 12.9 0.0 2.0 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain zf-ribbon_3 PF13248.6 GAM27124.1 - 0.032 13.6 2.2 3.3 7.3 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.17 GAM27124.1 - 0.044 13.7 0.3 0.12 12.2 0.3 1.8 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Cyclin_N PF00134.23 GAM27124.1 - 0.048 13.4 0.1 0.33 10.7 0.0 2.0 1 1 1 2 2 2 0 Cyclin, N-terminal domain ORC6 PF05460.13 GAM27124.1 - 0.059 12.6 0.9 0.16 11.2 0.8 1.6 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-RRN7 PF11781.8 GAM27124.1 - 0.13 12.0 1.4 0.35 10.6 1.4 1.8 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Sigma70_r4 PF04545.16 GAM27124.1 - 0.16 11.5 0.0 0.5 9.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 Prim_Zn_Ribbon PF08273.12 GAM27124.1 - 1.2 9.5 3.1 4.6 7.6 3.1 2.0 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Kelch_6 PF13964.6 GAM27125.1 - 7e-11 42.0 0.5 0.0051 17.1 0.0 3.8 2 1 1 3 3 3 3 Kelch motif Kelch_4 PF13418.6 GAM27125.1 - 0.00062 19.7 6.2 0.0048 16.9 0.1 3.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM27125.1 - 0.0087 15.6 2.7 0.022 14.4 0.0 2.6 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 GAM27125.1 - 0.018 15.3 0.0 0.39 11.1 0.0 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain Baculo_PEP_C PF04513.12 GAM27125.1 - 0.027 14.5 1.2 0.027 14.5 1.2 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-B_box PF00643.24 GAM27126.1 - 1.4e-06 28.3 1.8 3.3e-06 27.2 1.8 1.7 1 0 0 1 1 1 1 B-box zinc finger Baculo_PEP_C PF04513.12 GAM27126.1 - 0.01 15.9 0.1 0.019 15.0 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus 3HCDH_N PF02737.18 GAM27127.1 - 4.6e-62 209.1 3.0 5.7e-62 208.8 3.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 GAM27127.1 - 9.3e-36 122.3 0.0 2e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 GAM27127.1 - 3.7e-05 24.0 1.1 7.2e-05 23.1 1.1 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAM27127.1 - 3.8e-05 23.8 2.6 0.00014 21.9 2.4 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 GAM27127.1 - 0.00012 22.3 1.1 0.00039 20.6 1.2 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 GAM27127.1 - 0.00018 21.7 0.3 0.00038 20.7 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 GAM27127.1 - 0.00047 20.7 2.4 0.00081 19.9 1.6 1.9 2 1 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 GAM27127.1 - 0.00048 19.8 0.5 0.00077 19.1 0.5 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 GAM27127.1 - 0.0006 19.8 0.3 0.0013 18.8 0.3 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 GAM27127.1 - 0.0026 17.4 0.1 0.0035 17.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 GAM27127.1 - 0.0031 16.9 0.1 0.0064 15.9 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 GAM27127.1 - 0.004 16.4 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM27127.1 - 0.013 16.1 0.3 0.027 15.0 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAM27127.1 - 0.015 15.7 0.4 0.026 14.9 0.4 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Rossmann-like PF10727.9 GAM27127.1 - 0.051 13.4 0.6 0.23 11.3 0.3 2.3 3 1 0 3 3 3 0 Rossmann-like domain ELFV_dehydrog PF00208.21 GAM27127.1 - 0.059 13.1 0.3 0.087 12.5 0.3 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.20 GAM27127.1 - 0.067 13.3 1.4 0.15 12.2 1.4 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 GAM27127.1 - 0.077 12.9 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 KR domain Methyltransf_25 PF13649.6 GAM27127.1 - 0.14 12.9 0.0 0.32 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DAO PF01266.24 GAM27127.1 - 0.22 11.1 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Kelch_4 PF13418.6 GAM27128.1 - 7.9e-13 48.2 9.9 2.1e-06 27.6 0.0 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM27128.1 - 1.3e-10 41.1 12.8 0.00026 21.2 0.1 5.1 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 GAM27128.1 - 2.7e-07 30.0 3.1 0.0019 17.8 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 GAM27128.1 - 4e-07 30.2 0.5 0.053 13.8 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM27128.1 - 3.1e-05 23.8 4.3 0.25 11.4 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 GAM27128.1 - 0.0003 20.7 11.5 0.18 11.8 0.1 4.8 5 0 0 5 5 5 1 Kelch motif GBP PF02263.19 GAM27128.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Membralin PF09746.9 GAM27129.1 - 1.1e-16 60.9 4.9 1.5e-16 60.5 4.9 1.1 1 0 0 1 1 1 1 Tumour-associated protein PP2C PF00481.21 GAM27130.1 - 1.1e-53 182.5 0.0 2.8e-37 128.7 0.0 3.2 2 1 0 2 2 2 2 Protein phosphatase 2C SUIM_assoc PF16619.5 GAM27130.1 - 5 7.3 11.1 2.7 8.1 7.8 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FGGY_N PF00370.21 GAM27131.1 - 5.8e-67 225.8 0.1 6e-34 117.7 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAM27131.1 - 2.5e-65 219.9 0.8 4.8e-65 219.0 0.5 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain IP_trans PF02121.18 GAM27132.1 - 3.3e-112 374.1 0.2 3.7e-112 373.9 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein CTP_synth_N PF06418.14 GAM27134.1 - 1.4e-125 418.0 0.1 2e-125 417.4 0.1 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 GAM27134.1 - 3.6e-57 193.2 0.0 6.2e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAM27134.1 - 0.00011 22.0 2.3 0.12 12.1 0.0 3.1 3 1 1 4 4 4 2 Peptidase C26 CbiA PF01656.23 GAM27134.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain UcrQ PF02939.16 GAM27135.1 - 5e-14 52.0 0.2 5.4e-14 51.9 0.2 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 GAM27135.1 - 2.9e-07 30.8 0.1 3.2e-07 30.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 PilM PF07419.12 GAM27136.1 - 0.049 13.8 0.2 0.16 12.1 0.1 1.9 2 0 0 2 2 2 0 PilM SdrD_B PF17210.3 GAM27137.1 - 2.4e-83 275.7 142.7 6.8e-14 52.0 0.2 14.7 14 1 0 14 14 14 12 SdrD B-like domain DUF2141 PF09912.9 GAM27137.1 - 3.3e-14 52.7 13.4 0.21 11.5 0.0 11.1 13 0 0 13 13 13 6 Uncharacterized protein conserved in bacteria (DUF2141) MBF2 PF15868.5 GAM27137.1 - 0.023 15.2 1.5 60 4.3 0.0 5.9 6 0 0 6 6 6 0 Transcription activator MBF2 TbpB_A PF17484.2 GAM27137.1 - 0.26 12.0 3.3 9 7.1 0.1 4.2 4 0 0 4 4 4 0 N-Lobe handle Tf-binding protein B DUF919 PF06034.11 GAM27137.1 - 1.6 8.6 7.0 1.3e+02 2.5 0.0 5.1 6 0 0 6 6 6 0 Nucleopolyhedrovirus protein of unknown function (DUF919) HDV_ag PF01517.18 GAM27137.1 - 6 6.6 21.4 9.7 5.9 0.1 6.7 9 0 0 9 9 9 0 Hepatitis delta virus delta antigen LRR_6 PF13516.6 GAM27138.1 - 2.2e-20 70.9 34.2 0.0071 16.3 0.2 10.6 10 0 0 10 10 10 8 Leucine Rich repeat LRR_4 PF12799.7 GAM27138.1 - 0.00024 21.4 35.3 0.044 14.2 2.4 7.7 3 1 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM27138.1 - 0.081 13.5 17.8 42 5.2 0.0 7.9 6 1 0 6 6 6 0 Leucine Rich Repeat Ras PF00071.22 GAM27139.1 - 1.1e-33 116.2 0.1 1.3e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM27139.1 - 5.7e-20 71.7 0.0 9.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM27139.1 - 1.1e-11 44.5 0.3 1.4e-11 44.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM27139.1 - 1.2e-06 28.6 0.1 1.8e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM27139.1 - 4.7e-05 23.0 0.3 0.0047 16.5 0.3 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2057 PF09829.9 GAM27139.1 - 0.00087 19.5 1.5 0.0052 17.0 1.3 1.9 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2057) FeoB_N PF02421.18 GAM27139.1 - 0.002 17.6 0.4 0.093 12.3 0.1 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 GAM27139.1 - 0.0052 16.2 0.0 0.0066 15.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAM27139.1 - 0.0084 16.0 0.1 0.24 11.3 0.0 2.4 1 1 0 2 2 2 1 RsgA GTPase E1_dh PF00676.20 GAM27139.1 - 0.036 13.0 0.3 0.063 12.2 0.0 1.4 2 0 0 2 2 2 0 Dehydrogenase E1 component PduV-EutP PF10662.9 GAM27139.1 - 0.041 13.6 0.3 5.9 6.6 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 GAM27139.1 - 0.049 13.1 0.2 0.077 12.4 0.2 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 GAM27139.1 - 0.086 12.6 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 GAM27139.1 - 0.088 11.9 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain AAA PF00004.29 GAM27139.1 - 0.094 13.1 0.0 0.2 12.1 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 GAM27139.1 - 0.1 12.2 0.0 0.47 10.0 0.0 2.1 2 2 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAM27139.1 - 0.12 12.8 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 RNA helicase HMG-CoA_red PF00368.18 GAM27140.1 - 1.3e-145 485.0 2.1 1.8e-145 484.6 2.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase IFP_35_N PF07334.13 GAM27140.1 - 0.41 10.7 0.0 0.41 10.7 0.0 3.0 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Ten_N PF06484.12 GAM27140.1 - 2.3 8.0 5.1 3.4 7.5 5.1 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region WD40 PF00400.32 GAM27141.1 - 4.4e-26 90.6 23.8 0.00041 21.1 0.8 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 GAM27141.1 - 1.6e-05 24.4 0.8 8.4e-05 22.0 0.2 2.2 2 1 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 GAM27141.1 - 0.0034 17.6 3.3 0.095 13.0 0.3 3.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAM27141.1 - 0.0038 17.3 2.1 0.079 13.0 0.1 3.8 4 2 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region SH3_15 PF18346.1 GAM27141.1 - 4.3 7.7 8.0 2.1 8.7 0.0 3.6 2 1 0 3 3 3 0 Mind bomb SH3 repeat domain FA_FANCE PF11510.8 GAM27142.1 - 1.6e-11 44.1 6.3 2.8e-11 43.3 6.3 1.3 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE FNIP PF05725.12 GAM27143.1 - 3.1e-28 97.7 13.4 4.3e-10 39.6 0.0 6.4 3 2 4 7 7 7 7 FNIP Repeat PseudoU_synth_2 PF00849.22 GAM27144.1 - 3.6e-21 75.9 13.0 3.9e-20 72.5 4.4 4.3 2 1 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 GAM27144.1 - 0.0056 16.4 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 GAM27144.1 - 0.026 14.3 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 S4 domain Velvet PF11754.8 GAM27144.1 - 1.8 8.4 20.8 0.77 9.7 0.3 3.1 3 0 0 3 3 3 0 Velvet factor TFIIA PF03153.13 GAM27144.1 - 6 6.8 48.3 0.53 10.2 16.8 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 GAM27145.1 - 3e-52 177.6 0.0 4.1e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27145.1 - 2.5e-50 171.2 0.0 3.2e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM27145.1 - 0.00034 19.5 0.1 0.0006 18.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAM27145.1 - 0.0018 18.2 0.1 0.016 15.1 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM27145.1 - 0.011 14.7 0.4 0.19 10.6 0.4 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAM27145.1 - 0.034 13.5 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Keratin_matx PF04579.12 GAM27145.1 - 0.041 14.2 0.1 0.49 10.8 0.0 2.3 2 0 0 2 2 2 0 Keratin, high-sulphur matrix protein Ras PF00071.22 GAM27146.1 - 2.3e-37 128.1 0.0 2.9e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM27146.1 - 6.6e-08 32.8 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 GAM27146.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 GAM27146.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B ARID PF01388.21 GAM27147.1 - 2.5e-22 79.4 0.2 8.7e-21 74.4 0.0 2.7 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain SAP30_Sin3_bdg PF13867.6 GAM27147.1 - 3.1e-16 59.5 0.7 1e-15 57.8 0.7 2.0 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF1631 PF07793.11 GAM27147.1 - 0.13 10.6 2.7 0.16 10.4 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF1387 PF07139.11 GAM27147.1 - 1.2 8.8 15.4 1.9 8.1 15.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) FKBP_C PF00254.28 GAM27148.1 - 3.4e-27 94.6 0.1 1.5e-26 92.6 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.23 GAM27148.1 - 0.00085 19.2 0.2 0.0018 18.2 0.2 1.6 1 0 0 1 1 1 1 WH1 domain FUSC PF04632.12 GAM27148.1 - 8.6 4.8 6.3 16 3.9 6.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Oxidored_FMN PF00724.20 GAM27149.1 - 1.2e-72 245.1 0.0 1.4e-72 244.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 GAM27149.1 - 0.16 11.1 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Radical_SAM PF04055.21 GAM27150.1 - 1.6e-17 64.4 0.0 3.2e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 GAM27150.1 - 6.1e-06 26.4 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 GAM27150.1 - 0.0042 17.4 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain RMI2 PF16100.5 GAM27151.1 - 3.2e-10 39.9 0.0 8e-09 35.4 0.0 2.4 1 1 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 GAM27151.1 - 0.035 14.1 0.2 0.079 13.0 0.2 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MRF_C2 PF13888.6 GAM27151.1 - 0.073 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 SnoaL_2 PF12680.7 GAM27152.1 - 0.19 12.4 0.0 0.29 11.8 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain FNIP PF05725.12 GAM27153.1 - 7.2e-45 150.9 15.7 3.6e-13 49.4 0.2 5.9 4 1 2 7 7 7 6 FNIP Repeat LRR_5 PF13306.6 GAM27153.1 - 0.0075 16.2 0.0 0.038 14.0 0.0 2.0 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 GAM27154.1 - 3.1e-84 276.9 3.2 4.2e-14 52.4 0.4 8.1 7 1 0 8 8 8 7 FNIP Repeat FNIP PF05725.12 GAM27155.1 - 2e-70 232.7 14.7 2.4e-13 50.0 0.0 9.2 7 1 3 10 10 10 9 FNIP Repeat FNIP PF05725.12 GAM27156.1 - 1e-94 310.4 1.5 2.5e-13 50.0 0.0 8.2 5 1 2 8 8 8 8 FNIP Repeat Cyt-b5 PF00173.28 GAM27157.1 - 1.9e-21 76.0 0.0 2.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Myotub-related PF06602.14 GAM27158.1 - 2.1e-112 375.6 0.7 3.1e-112 375.0 0.0 1.6 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 GAM27158.1 - 0.0011 19.0 0.0 0.0033 17.4 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GAM27158.1 - 0.031 14.1 0.0 0.091 12.6 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain TMEM237 PF15383.6 GAM27158.1 - 1.8 7.6 7.2 0.35 9.9 3.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 237 Palm_thioest PF02089.15 GAM27159.1 - 0.027 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase ASH PF15780.5 GAM27160.1 - 8.5e-19 67.6 0.2 1.8e-08 34.5 0.0 4.8 4 0 0 4 4 4 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 GAM27160.1 - 0.0013 19.0 0.1 0.91 9.8 0.0 3.3 3 0 0 3 3 3 2 Transmembrane protein 131-like Coiled PF05710.12 GAM27161.1 - 0.0047 17.7 6.2 0.007 17.2 6.2 1.5 1 1 0 1 1 1 1 Coiled coil Tox-ART-HYD1 PF15633.6 GAM27162.1 - 9.9e-11 42.2 0.0 1.3e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 HYD1 signature containing ADP-ribosyltransferase PARP PF00644.20 GAM27162.1 - 0.077 12.6 0.1 0.09 12.4 0.1 1.2 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain Coiled PF05710.12 GAM27163.1 - 0.0099 16.7 10.0 0.015 16.1 10.0 1.5 1 1 0 1 1 1 1 Coiled coil Peptidase_M49 PF03571.15 GAM27164.1 - 1.2e-223 743.5 0.0 1.5e-223 743.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 MazG_C PF18722.1 GAM27164.1 - 0.041 13.4 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 MazG C-terminal domain DUF1439 PF07273.12 GAM27164.1 - 0.053 13.4 1.1 0.81 9.5 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1439) CCM2_C PF16545.5 GAM27164.1 - 0.16 12.5 0.1 25 5.5 0.0 2.9 3 0 0 3 3 3 0 Cerebral cavernous malformation protein, harmonin-homology BSP PF04450.12 GAM27165.1 - 3.8e-09 36.6 0.2 5.9e-09 36.0 0.2 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria CLIP PF12032.8 GAM27165.1 - 1.7e-08 34.6 75.8 0.35 11.2 1.9 9.5 9 0 0 9 9 9 8 Regulatory CLIP domain of proteinases PAP2 PF01569.21 GAM27166.1 - 1.2e-05 25.0 0.5 3.6e-05 23.6 0.5 1.8 1 0 0 1 1 1 1 PAP2 superfamily Imm52 PF15579.6 GAM27166.1 - 0.26 11.2 1.0 0.65 9.9 0.0 2.1 3 0 0 3 3 3 0 Immunity protein 52 BSP PF04450.12 GAM27167.1 - 9.1e-10 38.7 0.8 1.6e-09 37.8 0.8 1.4 1 0 0 1 1 1 1 Peptidase of plants and bacteria CfAFP PF05264.11 GAM27167.1 - 0.023 14.7 0.7 0.036 14.1 0.7 1.3 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF4419 PF14388.6 GAM27168.1 - 1e-94 317.4 1.3 1e-94 317.4 1.3 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4419) RPA43_OB PF17875.1 GAM27169.1 - 1.9e-05 25.3 0.0 1.9e-05 25.3 0.0 6.0 2 2 1 3 3 3 2 RPA43 OB domain in RNA Pol I RNA_pol_Rbc25 PF08292.12 GAM27169.1 - 0.0012 19.0 0.0 0.0012 19.0 0.0 4.3 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 GAM27169.1 - 0.023 15.0 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 F_actin_cap_B PF01115.17 GAM27171.1 - 1.1e-104 349.3 0.0 1.3e-104 349.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 GAM27171.1 - 0.027 13.9 0.2 0.2 11.0 0.1 2.4 1 1 1 2 2 2 0 F-actin capping protein alpha subunit Pkinase PF00069.25 GAM27172.1 - 2.7e-78 263.0 0.0 4e-78 262.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27172.1 - 5e-41 140.7 0.0 7.9e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 GAM27172.1 - 1.2e-06 28.2 0.1 3.6e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 Kinase associated domain 1 AdenylateSensor PF16579.5 GAM27172.1 - 3.3e-06 27.5 0.8 5.6e-05 23.6 0.3 2.8 2 1 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 GAM27172.1 - 3.3e-06 26.6 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 GAM27172.1 - 0.0011 18.7 1.0 0.0021 17.7 1.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAM27172.1 - 0.0059 16.0 0.2 0.015 14.7 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM27172.1 - 0.012 15.5 0.1 0.22 11.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM27172.1 - 0.063 12.9 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Apc15p PF05841.11 GAM27172.1 - 0.063 14.1 4.5 1.4 9.7 0.5 2.3 2 0 0 2 2 2 0 Apc15p protein ABC1 PF03109.16 GAM27172.1 - 0.12 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Macoilin PF09726.9 GAM27172.1 - 9 4.7 9.3 1.5 7.3 3.3 2.0 2 0 0 2 2 2 0 Macoilin family PPR_3 PF13812.6 GAM27173.1 - 5.4e-06 26.4 6.7 0.0074 16.3 0.2 4.6 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAM27173.1 - 6e-06 26.4 9.0 0.055 13.7 0.1 6.7 6 0 0 6 6 6 2 PPR repeat family NACHT PF05729.12 GAM27173.1 - 0.0088 16.0 0.1 0.027 14.4 0.1 1.8 1 1 0 1 1 1 1 NACHT domain PPR PF01535.20 GAM27173.1 - 0.045 14.0 11.7 17 5.9 0.1 7.0 7 0 0 7 7 7 0 PPR repeat PPR_1 PF12854.7 GAM27173.1 - 2.6 7.8 6.2 4 7.2 0.0 4.0 5 0 0 5 5 5 0 PPR repeat Ank_2 PF12796.7 GAM27174.1 - 3e-07 30.9 0.4 0.032 14.8 0.1 5.3 3 1 3 6 6 6 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM27174.1 - 4.6e-06 27.1 0.6 3.1 8.5 0.0 5.7 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM27174.1 - 0.0016 18.7 2.1 2.9 8.7 0.1 5.8 6 0 0 6 6 6 1 Ankyrin repeat DUF3447 PF11929.8 GAM27174.1 - 0.043 13.8 4.0 0.63 10.0 0.2 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF3447) Ank_5 PF13857.6 GAM27174.1 - 0.1 12.9 0.0 47 4.5 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) PTPLA PF04387.14 GAM27175.1 - 2.3e-54 183.6 11.8 2.3e-54 183.6 11.8 2.0 2 0 0 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA NUP50 PF08911.11 GAM27176.1 - 9.8e-12 45.4 3.0 9.8e-12 45.4 3.0 5.0 4 3 1 5 5 5 1 NUP50 (Nucleoporin 50 kDa) zf-RanBP PF00641.18 GAM27176.1 - 1.4 8.3 37.2 1.1 8.6 7.8 3.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 GAM27176.1 - 2.3 8.3 18.4 2.5 8.2 0.4 4.0 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger PPR_2 PF13041.6 GAM27177.1 - 4.3e-06 26.8 0.1 0.09 13.0 0.0 5.1 5 0 0 5 5 5 1 PPR repeat family TPR_16 PF13432.6 GAM27177.1 - 0.0016 19.1 1.0 0.54 10.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM27177.1 - 0.0083 16.4 1.2 0.77 10.1 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM27177.1 - 0.016 15.7 3.6 1 10.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM27177.1 - 0.023 15.5 0.6 2.2 9.3 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4458 PF14660.6 GAM27177.1 - 0.028 14.7 0.1 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4458) DHQS PF01959.16 GAM27177.1 - 0.039 12.9 0.1 0.067 12.1 0.1 1.3 1 0 0 1 1 1 0 3-dehydroquinate synthase II TPR_2 PF07719.17 GAM27177.1 - 0.045 13.9 1.7 4.7 7.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAM27177.1 - 0.074 13.7 7.5 0.17 12.6 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF5308 PF17233.2 GAM27177.1 - 1.1 9.4 11.7 0.038 14.2 4.7 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5308) ATP-synt_S1 PF05827.12 GAM27178.1 - 1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Orthoreo_P10 PF07204.11 GAM27178.1 - 0.046 13.7 0.1 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Dicty_CAR PF05462.11 GAM27179.1 - 2.1e-159 529.6 27.2 2.8e-159 529.1 27.2 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 GAM27179.1 - 6.8e-12 45.2 22.8 6.8e-12 45.2 22.8 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Peroxin-13_N PF04088.13 GAM27179.1 - 0.0058 16.9 0.1 5.3 7.3 0.0 2.6 2 1 0 2 2 2 2 Peroxin 13, N-terminal region DUF4229 PF14012.6 GAM27179.1 - 1.1 9.4 4.7 1.7 8.8 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) FA_desaturase PF00487.24 GAM27180.1 - 3.9e-37 128.5 14.7 6e-37 127.8 14.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAM27180.1 - 3e-23 81.8 0.1 1.6e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 GAM27180.1 - 0.063 13.4 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Methyltr_RsmB-F PF01189.17 GAM27181.1 - 3.3e-44 150.9 0.0 5.4e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 GAM27181.1 - 3.2e-08 33.5 0.0 5.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 GAM27181.1 - 1.2e-07 32.0 0.0 2.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PUA PF01472.20 GAM27181.1 - 4.2e-05 23.4 0.1 9.2e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 PUA domain Methyltransf_25 PF13649.6 GAM27181.1 - 0.021 15.5 0.0 0.12 13.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 GAM27181.1 - 0.055 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 GAM27181.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 YjbH PF06082.11 GAM27182.1 - 0.1 11.4 2.4 0.14 10.9 2.4 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DSHCT PF08148.12 GAM27183.1 - 4.1e-48 163.2 0.2 8.9e-48 162.0 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 GAM27183.1 - 6.3e-36 124.7 2.0 1.5e-35 123.4 2.0 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 GAM27183.1 - 5.9e-18 65.2 0.2 1.6e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ski2_N PF17911.1 GAM27183.1 - 4.2e-13 49.3 2.3 4.3e-13 49.2 0.0 2.1 2 0 0 2 2 2 1 Ski2 N-terminal region Helicase_C PF00271.31 GAM27183.1 - 3.9e-06 27.2 0.0 5.3e-05 23.5 0.0 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM27183.1 - 1.8e-05 24.8 0.0 1.8e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIA PF03153.13 GAM27183.1 - 0.016 15.2 2.7 0.032 14.3 2.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BSP_II PF05432.11 GAM27183.1 - 0.094 12.4 13.4 0.16 11.6 13.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MAT1 PF06391.13 GAM27183.1 - 0.19 11.5 7.7 0.018 14.9 2.1 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Nop14 PF04147.12 GAM27183.1 - 0.44 8.7 15.9 0.91 7.7 13.1 2.0 2 0 0 2 2 2 0 Nop14-like family PIEZO PF15917.5 GAM27183.1 - 0.67 9.4 4.7 0.55 9.7 0.5 2.2 2 0 0 2 2 2 0 Piezo Sporozoite_P67 PF05642.11 GAM27183.1 - 0.81 7.7 5.3 2.2 6.3 5.3 1.7 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.11 GAM27183.1 - 1.2 9.1 6.3 3.1 7.8 6.3 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 GAM27183.1 - 5.5 6.3 12.6 9.2 5.6 12.6 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GAM27183.1 - 7.3 4.5 15.8 12 3.8 15.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi MOZ_SAS PF01853.18 GAM27184.1 - 6.5e-88 293.1 0.2 1.6e-87 291.8 0.2 1.7 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAM27184.1 - 3.3e-26 90.6 3.2 3.3e-26 90.6 3.2 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 GAM27184.1 - 2.5e-20 72.1 2.7 5.2e-20 71.1 2.7 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 GAM27184.1 - 0.014 15.9 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM27184.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RRM_1 PF00076.22 GAM27185.1 - 1.1e-15 57.2 0.0 1.5e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM27185.1 - 2.4e-05 24.4 0.0 0.00012 22.1 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 GAM27185.1 - 0.034 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 GAM27186.1 - 9.9e-47 159.5 1.6 1.1e-33 116.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27186.1 - 2.4e-29 102.4 0.1 1.1e-28 100.2 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_1 PF00583.25 GAM27186.1 - 5.8e-06 26.5 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM27186.1 - 0.00055 19.9 0.0 0.0023 17.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM27186.1 - 0.0027 18.1 0.0 0.0058 17.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SOG2 PF10428.9 GAM27186.1 - 0.32 10.1 13.4 0.47 9.6 13.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein T2SSppdC PF12528.8 GAM27186.1 - 0.75 10.6 7.4 1.6 9.5 7.4 1.5 1 0 0 1 1 1 0 Type II secretion prepilin peptidase dependent protein C DUF3682 PF12446.8 GAM27186.1 - 4.1 7.9 10.1 8 7.0 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Kelch_3 PF13415.6 GAM27186.1 - 6.4 7.2 6.0 0.83 10.0 1.7 1.8 2 0 0 2 2 2 0 Galactose oxidase, central domain LRR_6 PF13516.6 GAM27187.1 - 1.6e-26 90.0 59.8 0.013 15.5 0.1 16.3 17 0 0 17 17 17 11 Leucine Rich repeat LRR_4 PF12799.7 GAM27187.1 - 1.4e-06 28.5 52.6 3.1 8.3 0.0 10.8 5 3 7 12 12 12 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM27187.1 - 0.00014 22.0 36.3 6.5 7.7 1.4 13.6 14 3 0 14 14 14 1 Leucine Rich Repeat LRR_8 PF13855.6 GAM27187.1 - 0.0042 16.8 54.2 2.8 7.8 0.1 11.2 6 4 4 10 10 10 5 Leucine rich repeat RAD51_interact PF15696.5 GAM27187.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.6 2 0 0 2 2 2 0 RAD51 interacting motif Hamartin PF04388.12 GAM27187.1 - 3.7 6.1 18.2 5.3 5.6 18.2 1.1 1 0 0 1 1 1 0 Hamartin protein MM_CoA_mutase PF01642.22 GAM27188.1 - 1.7e-236 785.7 0.8 2.2e-236 785.4 0.8 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 GAM27188.1 - 2.1e-14 53.6 0.2 4.4e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 B12 binding domain PhnI PF05861.12 GAM27188.1 - 0.032 13.1 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) ChlI PF13541.6 GAM27188.1 - 0.081 12.8 0.7 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase Pkinase PF00069.25 GAM27189.1 - 2.3e-76 256.7 0.3 4.6e-76 255.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27189.1 - 9.1e-37 126.7 0.0 1.6e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM27189.1 - 4.6e-06 26.1 0.0 8.9e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAM27189.1 - 0.00091 18.1 0.0 0.00091 18.1 0.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAM27189.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.27 GAM27191.1 - 5.5e-09 35.9 0.0 7.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FNIP PF05725.12 GAM27192.1 - 1.5e-48 162.7 27.9 1.7e-11 44.1 0.5 7.6 3 3 2 8 8 8 8 FNIP Repeat DUF4551 PF15087.6 GAM27193.1 - 7.5 5.3 19.1 9.1 5.0 19.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.7 GAM27193.1 - 9.1 4.3 16.0 10 4.1 16.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Forkhead PF00250.18 GAM27194.1 - 0.00091 19.4 0.0 0.0038 17.4 0.0 2.0 2 0 0 2 2 2 1 Forkhead domain Oxysterol_BP PF01237.18 GAM27195.1 - 9e-60 202.5 0.0 1.3e-59 201.9 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein FAM60A PF15396.6 GAM27195.1 - 0.085 12.8 0.9 0.2 11.6 0.1 2.0 3 0 0 3 3 3 0 Protein Family FAM60A PhoLip_ATPase_C PF16212.5 GAM27196.1 - 1.7e-62 211.4 27.6 1.7e-62 211.4 27.6 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM27196.1 - 3.4e-25 87.5 4.6 4.3e-25 87.2 0.3 2.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GAM27196.1 - 8.7e-16 58.8 0.1 2.1e-07 31.4 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM27196.1 - 1.4e-11 44.3 0.0 5.2e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GAM27196.1 - 4.8e-10 39.3 3.1 7.6e-10 38.6 0.0 2.6 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAM27196.1 - 0.00018 21.4 0.0 0.021 14.6 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 GAM27196.1 - 0.14 11.6 0.3 0.24 10.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Pentapeptide PF00805.22 GAM27197.1 - 2.6e-23 81.2 23.4 1.4e-08 34.2 2.0 4.8 1 1 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 GAM27197.1 - 1e-18 67.2 19.3 1.6e-07 31.4 0.9 3.5 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 GAM27197.1 - 5.6e-16 58.4 18.8 6e-07 29.5 0.3 4.8 2 1 4 6 6 6 5 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 GAM27197.1 - 2.1e-07 31.2 0.0 5.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain AF-4 PF05110.13 GAM27197.1 - 0.72 7.9 7.1 0.98 7.4 7.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FNIP PF05725.12 GAM27198.1 - 4.5e-96 314.8 63.1 6.7e-15 55.0 1.9 9.1 3 2 11 14 14 14 12 FNIP Repeat MMR_HSR1 PF01926.23 GAM27199.1 - 1.9e-15 56.9 0.2 2.5e-13 50.1 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM27199.1 - 8.2e-07 28.7 0.9 2.4e-05 23.9 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAM27199.1 - 4.2e-05 23.5 1.3 0.15 12.0 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase cobW PF02492.19 GAM27199.1 - 0.0074 15.9 0.0 0.044 13.4 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IceA2 PF05862.11 GAM27199.1 - 0.18 11.7 0.8 0.51 10.3 0.8 1.7 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein Mito_carr PF00153.27 GAM27200.1 - 1.4e-50 169.2 4.8 1.2e-18 66.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RrnaAD PF00398.20 GAM27201.1 - 1.6e-50 171.7 0.0 2.2e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 GAM27201.1 - 0.0004 21.0 0.3 0.0009 19.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAM27201.1 - 0.039 13.9 0.4 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 GAM27201.1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 GAM27201.1 - 0.1 13.3 0.0 0.25 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 GAM27201.1 - 0.23 11.0 0.8 0.92 9.1 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RyR PF02026.16 GAM27201.1 - 1 9.6 3.3 0.51 10.6 0.8 1.8 2 0 0 2 2 2 0 RyR domain VIT PF08487.10 GAM27202.1 - 3.9e-31 107.5 0.7 8.5e-31 106.5 0.7 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 GAM27202.1 - 7.2e-27 94.2 0.0 1.8e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAM27202.1 - 2e-11 44.5 0.0 4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM27202.1 - 2.6e-09 37.7 0.0 1.2e-08 35.5 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 GAM27202.1 - 0.00024 20.9 0.3 0.00084 19.2 0.1 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain DUF5349 PF17298.2 GAM27202.1 - 0.0019 18.1 3.8 0.0039 17.0 3.8 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5349) Neuraminidase PF18413.1 GAM27202.1 - 0.33 10.6 1.6 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Neuraminidase-like domain RSN1_7TM PF02714.15 GAM27203.1 - 3.2e-69 233.3 20.8 3.2e-69 233.3 20.8 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAM27203.1 - 6.3e-31 107.3 4.4 6.3e-31 107.3 4.4 3.2 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAM27203.1 - 1e-20 74.7 1.5 5.3e-20 72.4 1.5 2.0 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Nodulin_late PF07127.11 GAM27204.1 - 7.1 7.1 8.6 38 4.7 1.7 3.2 2 0 0 2 2 2 0 Late nodulin protein Amidohydro_1 PF01979.20 GAM27205.1 - 6.1e-62 209.9 2.6 9.4e-62 209.3 2.6 1.2 1 0 0 1 1 1 1 Amidohydrolase family NOG1_N PF17835.1 GAM27205.1 - 2.1e-52 177.3 1.4 5e-52 176.1 1.4 1.6 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 GAM27205.1 - 3.3e-26 90.8 0.5 9.3e-26 89.4 0.5 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 GAM27205.1 - 5.9e-19 68.2 0.0 2.8e-18 66.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase NOGCT PF08155.11 GAM27205.1 - 3.2e-18 65.4 4.5 9.9e-18 63.9 4.5 1.9 1 0 0 1 1 1 1 NOGCT (NUC087) domain FeoB_N PF02421.18 GAM27205.1 - 5.9e-12 45.4 0.0 1.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Amidohydro_3 PF07969.11 GAM27205.1 - 5.9e-08 32.6 0.6 1.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family AIG1 PF04548.16 GAM27205.1 - 0.0017 17.7 0.2 0.023 14.0 0.0 2.7 3 0 0 3 3 3 1 AIG1 family Roc PF08477.13 GAM27205.1 - 0.011 16.0 0.1 0.31 11.2 0.0 3.1 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GAM27205.1 - 0.017 15.0 0.0 0.26 11.2 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase A_deaminase PF00962.22 GAM27205.1 - 0.02 14.2 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenosine/AMP deaminase AAA_16 PF13191.6 GAM27205.1 - 0.021 15.2 0.1 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 GAM27205.1 - 0.026 14.0 0.0 0.069 12.6 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MeaB PF03308.16 GAM27205.1 - 0.033 13.2 0.0 8.6 5.2 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 GAM27205.1 - 0.23 11.5 3.2 2 8.4 0.0 2.9 2 1 0 3 3 2 0 Dynamin family AAA_18 PF13238.6 GAM27205.1 - 0.38 11.3 0.0 0.38 11.3 0.0 3.8 4 1 0 4 4 3 0 AAA domain Transformer PF06495.11 GAM27205.1 - 0.44 10.6 8.4 0.83 9.7 8.4 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein DUF480 PF04337.12 GAM27205.1 - 0.54 10.3 2.8 0.37 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF480 DEAD_2 PF06733.15 GAM27206.1 - 1.9e-54 183.9 0.4 3.9e-54 182.9 0.4 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 GAM27206.1 - 1.3e-46 158.9 0.1 2.9e-46 157.8 0.1 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 GAM27206.1 - 4.8e-37 127.5 0.5 2.4e-32 112.1 0.1 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 GAM27206.1 - 2e-05 24.7 0.0 0.00023 21.2 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 GAM27206.1 - 0.00069 18.4 0.1 0.019 13.7 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 GAM27206.1 - 0.032 14.5 0.0 9.5 6.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain Thioredoxin PF00085.20 GAM27207.1 - 1.6e-49 166.1 0.1 2.9e-29 101.1 0.1 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 GAM27207.1 - 1e-10 42.0 0.9 4.3e-05 23.9 0.1 2.6 2 1 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 GAM27207.1 - 2.3e-07 30.8 0.3 0.00082 19.3 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 GAM27207.1 - 9.8e-07 29.0 0.1 0.081 13.3 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like TraF PF13728.6 GAM27207.1 - 3e-06 27.2 0.2 0.092 12.6 0.0 2.8 3 0 0 3 3 3 2 F plasmid transfer operon protein Redoxin PF08534.10 GAM27207.1 - 5e-05 23.0 0.4 0.038 13.7 0.0 2.4 2 1 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.6 GAM27207.1 - 0.00022 21.2 0.0 0.72 9.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAM27207.1 - 0.00023 21.3 0.1 0.05 13.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 GAM27207.1 - 0.00024 21.1 0.1 0.51 10.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_9 PF14595.6 GAM27207.1 - 0.0064 16.3 0.1 0.92 9.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin EpuA PF11772.8 GAM27207.1 - 0.025 14.3 1.5 0.054 13.2 1.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta OST3_OST6 PF04756.13 GAM27207.1 - 0.067 12.5 0.6 5.7 6.2 0.0 2.8 1 1 1 2 2 2 0 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 GAM27207.1 - 0.33 11.2 1.6 21 5.5 0.2 2.6 2 0 0 2 2 2 0 Glutaredoxin Hpt PF01627.23 GAM27208.1 - 1.5e-09 38.0 0.0 2.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Hpt domain PPR PF01535.20 GAM27208.1 - 0.00054 20.0 0.5 0.0012 18.9 0.5 1.6 1 0 0 1 1 1 1 PPR repeat PPR_1 PF12854.7 GAM27208.1 - 0.0056 16.3 0.2 0.013 15.2 0.2 1.7 1 0 0 1 1 1 1 PPR repeat Menin PF05053.13 GAM27208.1 - 0.16 10.3 6.1 0.21 9.9 6.1 1.1 1 0 0 1 1 1 0 Menin PPR_2 PF13041.6 GAM27208.1 - 0.26 11.5 1.5 0.36 11.1 0.2 1.9 2 0 0 2 2 2 0 PPR repeat family Macoilin PF09726.9 GAM27208.1 - 0.86 8.1 11.3 1.2 7.6 11.3 1.2 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 GAM27208.1 - 6.3 5.5 4.8 7.6 5.2 4.8 1.1 1 0 0 1 1 1 0 Presenilin RA PF00788.23 GAM27209.1 - 0.0018 18.9 0.0 0.0039 17.8 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain YL1 PF05764.13 GAM27209.1 - 0.0076 16.4 0.5 0.0076 16.4 0.5 2.1 2 0 0 2 2 2 1 YL1 nuclear protein Tir_receptor_C PF07489.11 GAM27210.1 - 0.51 10.3 7.3 1.2 9.1 7.3 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Pur_ac_phosph_N PF16656.5 GAM27211.1 - 1.4e-18 67.2 1.5 1.4e-18 67.2 1.5 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 GAM27211.1 - 1.5e-16 61.0 0.2 3.6e-16 59.8 0.2 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.28 GAM27211.1 - 1.7e-16 61.4 2.9 2.9e-16 60.6 1.9 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAM27211.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PseudoU_synth_1 PF01416.20 GAM27212.1 - 7.2e-32 110.1 0.0 4e-22 78.7 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase U-box PF04564.15 GAM27214.1 - 2.1e-08 34.2 0.1 1.1e-07 31.9 0.1 2.2 1 1 0 1 1 1 1 U-box domain zf-Nse PF11789.8 GAM27214.1 - 0.0085 15.9 0.2 0.031 14.1 0.1 2.0 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit EthD PF07110.11 GAM27214.1 - 0.018 16.1 0.4 1.6 9.9 0.1 2.7 1 1 0 2 2 2 0 EthD domain zf-rbx1 PF12678.7 GAM27214.1 - 0.03 14.6 0.0 0.068 13.5 0.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF3636 PF12331.8 GAM27214.1 - 0.054 13.3 0.2 5.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) zf-C3HC4_2 PF13923.6 GAM27214.1 - 0.066 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PI3K_1B_p101 PF10486.9 GAM27214.1 - 9.1 3.9 9.9 5.2 4.7 0.9 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1772 PF08592.11 GAM27215.1 - 2.5e-10 40.8 1.0 2.5e-10 40.8 1.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Herpes_LMP2 PF07415.11 GAM27215.1 - 0.031 13.1 0.1 0.035 12.9 0.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein UPF0020 PF01170.18 GAM27216.1 - 3e-07 30.3 0.1 0.00017 21.3 0.1 2.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 GAM27216.1 - 1.7e-05 24.7 2.3 0.00074 19.3 0.0 3.2 3 1 0 3 3 3 2 DNA methylase AhpC-TSA_2 PF13911.6 GAM27217.1 - 1.2e-17 64.1 0.0 2.5e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 GAM27217.1 - 2.2e-05 24.3 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAM27217.1 - 0.044 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Redoxin FAE1_CUT1_RppA PF08392.12 GAM27218.1 - 1.6e-126 421.5 0.0 2.1e-126 421.1 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 GAM27218.1 - 7.3e-11 42.1 0.0 4.9e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 GAM27218.1 - 4.6e-10 39.7 0.0 8.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain 60KD_IMP PF02096.20 GAM27218.1 - 0.0057 16.6 1.0 0.012 15.6 1.0 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein ACP_syn_III PF08545.10 GAM27218.1 - 0.046 13.6 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 GAM27218.1 - 0.17 11.2 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain GST_N PF02798.20 GAM27219.1 - 5.2e-12 45.9 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAM27219.1 - 1.9e-11 44.2 0.0 3.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM27219.1 - 2.4e-11 43.7 0.0 4.8e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM27219.1 - 6e-10 39.3 0.0 1.4e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM27219.1 - 1.3e-09 38.1 0.1 2.2e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM27219.1 - 9.7e-07 28.7 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM27220.1 - 2.9e-20 72.3 0.0 4.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM27220.1 - 2.8e-08 33.9 0.0 4.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM27220.1 - 1.5e-06 28.5 0.0 3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM27220.1 - 3e-06 27.2 0.1 1.8e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF3683 PF12447.8 GAM27220.1 - 0.042 14.0 0.0 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) GST_C_6 PF17171.4 GAM27220.1 - 0.05 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Malate_synthase PF01274.22 GAM27221.1 - 1.8e-98 330.1 0.0 6e-98 328.4 0.0 1.6 1 1 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 GAM27221.1 - 0.16 11.1 0.0 1.5 7.9 0.0 2.3 3 0 0 3 3 3 0 HpcH/HpaI aldolase/citrate lyase family PIGA PF08288.12 GAM27222.1 - 9.4e-44 147.9 1.4 1.6e-43 147.2 0.4 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 GAM27222.1 - 4.2e-27 94.8 0.0 6.6e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAM27222.1 - 7.1e-27 94.5 0.0 1.1e-26 93.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAM27222.1 - 3.8e-22 79.2 0.0 6.1e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAM27222.1 - 2e-06 28.3 0.0 3.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 GAM27222.1 - 0.00075 19.5 0.1 0.0013 18.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 GAM27222.1 - 0.0057 17.0 0.0 0.016 15.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 GAM27222.1 - 0.16 11.6 0.0 0.41 10.3 0.0 1.8 1 1 0 1 1 1 0 Starch synthase catalytic domain eIF-5a PF01287.20 GAM27223.1 - 5.3e-25 87.3 0.3 7.3e-25 86.9 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 GAM27223.1 - 0.099 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain PLDc_2 PF13091.6 GAM27224.1 - 2.3e-08 34.0 0.1 0.00048 20.0 0.0 3.6 2 2 1 3 3 3 2 PLD-like domain PLDc PF00614.22 GAM27224.1 - 1.4e-06 28.2 0.3 0.0041 17.3 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif TFIIA PF03153.13 GAM27224.1 - 0.00059 20.0 10.2 0.00096 19.3 10.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 GAM27224.1 - 0.063 12.7 8.8 0.13 11.6 8.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pribosyltran PF00156.27 GAM27224.1 - 0.2 11.2 0.1 0.99 8.9 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosyl transferase domain FNIP PF05725.12 GAM27225.1 - 1.7e-35 120.9 11.0 1.1e-09 38.3 0.0 5.7 4 2 1 5 5 5 5 FNIP Repeat PhoLip_ATPase_C PF16212.5 GAM27227.1 - 4.5e-85 285.4 22.8 4.5e-85 285.4 22.8 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM27227.1 - 6.1e-29 99.5 1.7 6.1e-29 99.5 1.7 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAM27227.1 - 8.3e-14 51.5 0.0 6.3e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GAM27227.1 - 5.8e-11 42.2 0.0 8.2e-10 38.5 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAM27227.1 - 1.6e-08 35.1 0.7 0.0033 17.8 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAM27227.1 - 0.01 15.6 0.1 0.032 14.0 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ArgJ PF01960.18 GAM27227.1 - 0.13 10.9 0.2 0.24 10.1 0.2 1.3 1 0 0 1 1 1 0 ArgJ family TIG PF01833.24 GAM27228.1 - 9.7e-17 60.8 81.3 2.9e-07 30.5 2.8 11.1 10 2 2 12 12 12 7 IPT/TIG domain EGF_2 PF07974.13 GAM27228.1 - 4.5 7.7 13.3 2.3 8.7 10.6 1.9 2 0 0 2 2 2 0 EGF-like domain Pentapeptide_4 PF13599.6 GAM27229.1 - 1.7e-16 60.1 42.0 4.4e-09 36.4 12.2 3.3 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 GAM27229.1 - 1.4e-10 40.6 17.6 1.2e-05 24.8 5.9 4.5 4 1 1 5 5 5 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 GAM27229.1 - 2.1e-10 40.6 27.7 7.5e-05 22.8 6.7 3.5 2 1 0 3 3 3 3 Pentapeptide repeats (9 copies) zf-RING_2 PF13639.6 GAM27229.1 - 0.018 15.3 14.3 0.018 15.3 14.3 2.7 2 0 0 2 2 2 0 Ring finger domain GEP5 PF17053.5 GAM27229.1 - 0.44 10.3 3.4 0.76 9.6 3.4 1.3 1 0 0 1 1 1 0 Genetic interactor of prohibitin 5 zf-RING_UBOX PF13445.6 GAM27229.1 - 1.5 8.9 12.9 6.3 6.9 12.9 2.2 1 0 0 1 1 1 0 RING-type zinc-finger TFIIA PF03153.13 GAM27229.1 - 2.3 8.1 11.0 3.4 7.6 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Prefoldin PF02996.17 GAM27230.1 - 9.1e-18 64.3 0.2 9.1e-18 64.3 0.2 2.9 2 1 1 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.6 GAM27230.1 - 1.4e-06 28.3 0.1 1.4e-06 28.3 0.1 3.5 2 1 2 4 4 4 1 Prefoldin subunit Myosin_head PF00063.21 GAM27231.1 - 5.1e-225 748.7 8.6 5.1e-225 748.7 8.6 2.4 3 0 0 3 3 3 1 Myosin head (motor domain) DIL PF01843.19 GAM27231.1 - 3e-23 82.1 2.0 1.6e-22 79.7 0.9 2.9 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 GAM27231.1 - 1.6e-07 30.5 15.0 0.0018 17.9 1.1 5.3 6 0 0 6 6 6 2 IQ calmodulin-binding motif AAA_16 PF13191.6 GAM27231.1 - 0.0095 16.3 1.1 0.29 11.5 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM27231.1 - 0.011 16.0 0.4 0.15 12.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain Csm1_N PF18504.1 GAM27231.1 - 1.2 9.6 25.2 0.35 11.2 11.8 3.5 2 1 1 3 3 3 0 Csm1 N-terminal domain Atg14 PF10186.9 GAM27231.1 - 4.5 6.3 24.9 0.72 8.9 16.2 2.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TFR_dimer PF04253.15 GAM27231.1 - 8.1 6.6 7.5 4.5 7.4 3.8 2.6 2 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain DUF4407 PF14362.6 GAM27231.1 - 8.8 5.6 18.2 8.1 5.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) KASH_CCD PF14662.6 GAM27231.1 - 9.4 6.0 33.6 2 8.2 24.9 2.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Myosin_N PF02736.19 GAM27232.1 - 4.5e-07 29.6 0.4 6.5e-07 29.1 0.4 1.3 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain FNIP PF05725.12 GAM27233.1 - 1.1e-67 223.9 5.4 2.9e-13 49.7 0.0 9.8 5 4 3 9 9 9 9 FNIP Repeat DUF1769 PF08588.10 GAM27233.1 - 5.7e-06 26.4 5.2 26 5.1 0.0 7.7 7 2 2 9 9 9 1 Protein of unknown function (DUF1769) Cation_ATPase_C PF00689.21 GAM27234.1 - 2.3e-44 151.3 7.2 2.8e-44 151.0 2.2 2.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAM27234.1 - 3.9e-39 134.0 0.1 3.9e-39 134.0 0.1 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAM27234.1 - 2.3e-19 69.3 0.0 4.2e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM27234.1 - 8.9e-17 62.1 0.3 6.2e-16 59.3 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAM27234.1 - 2.4e-12 46.4 0.0 5.2e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM27234.1 - 0.00017 21.4 0.1 0.0074 16.1 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3953 PF13129.6 GAM27234.1 - 0.08 12.7 1.2 0.28 11.0 1.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) DUF4199 PF13858.6 GAM27234.1 - 3.4 8.0 8.2 0.83 10.0 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) F-box-like PF12937.7 GAM27235.1 - 0.015 15.2 0.7 0.035 14.0 0.0 2.0 2 0 0 2 2 2 0 F-box-like LRR_6 PF13516.6 GAM27235.1 - 0.25 11.5 14.7 1.9 8.8 0.2 4.6 4 0 0 4 4 4 0 Leucine Rich repeat Stealth_CR2 PF11380.8 GAM27236.1 - 9.9e-40 135.1 5.7 1.5e-39 134.5 1.6 2.8 3 1 0 3 3 3 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 GAM27236.1 - 8.3e-14 51.2 0.3 2.2e-13 49.9 0.3 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 GAM27236.1 - 3.9e-12 45.7 0.0 7.6e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 GAM27236.1 - 3.2e-10 39.7 1.2 8.6e-10 38.4 0.2 2.2 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Legionella_OMP PF05150.12 GAM27236.1 - 0.00087 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Legionella pneumophila major outer membrane protein precursor Oxysterol_BP PF01237.18 GAM27237.1 - 2.4e-104 349.2 1.1 2.9e-104 348.9 1.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein RasGEF PF00617.19 GAM27238.1 - 8.5e-54 182.4 1.0 9.8e-52 175.7 0.1 2.7 2 0 0 2 2 2 1 RasGEF domain LRR_8 PF13855.6 GAM27238.1 - 2.3e-32 110.5 37.9 6.6e-10 38.6 6.0 5.8 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 GAM27238.1 - 3e-29 100.6 35.5 1e-07 32.1 0.1 7.3 7 0 0 7 7 7 6 Leucine Rich repeats (2 copies) RasGEF_N PF00618.20 GAM27238.1 - 4.1e-19 68.8 2.6 6.3e-19 68.2 0.1 2.7 3 0 0 3 3 3 1 RasGEF N-terminal motif LRR_9 PF14580.6 GAM27238.1 - 1.9e-08 34.0 17.9 0.0039 16.7 2.9 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_5 PF13306.6 GAM27238.1 - 0.0017 18.3 0.2 0.48 10.4 0.0 3.6 2 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) SNF2_N PF00176.23 GAM27238.1 - 0.014 14.1 0.1 0.027 13.2 0.1 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain LRR_1 PF00560.33 GAM27238.1 - 0.028 14.9 29.8 7.9 7.5 0.1 10.5 10 2 1 11 11 11 0 Leucine Rich Repeat IQ PF00612.27 GAM27238.1 - 1.3 9.0 16.5 0.39 10.6 4.1 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif SPX PF03105.19 GAM27238.1 - 4 7.2 11.5 6.5 6.6 11.5 1.3 1 0 0 1 1 1 0 SPX domain DUF3361 PF11841.8 GAM27239.1 - 1.8e-05 24.7 4.7 2.6e-05 24.2 4.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Fucokinase PF07959.12 GAM27239.1 - 0.31 9.9 4.5 0.36 9.7 4.5 1.0 1 0 0 1 1 1 0 L-fucokinase Dicty_spore_N PF04562.12 GAM27240.1 - 4.8e-45 152.9 50.0 1.7e-25 89.9 22.9 6.6 3 2 3 6 6 6 2 Dictyostelium spore coat protein, N terminus Aa_trans PF01490.18 GAM27241.1 - 1.1e-12 47.4 37.4 2.1e-12 46.5 37.4 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAM27241.1 - 7.1e-05 22.0 20.7 7.1e-05 22.0 20.7 2.5 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family Ribosomal_S30 PF04758.14 GAM27242.1 - 2.7e-15 56.3 6.5 3.1e-15 56.1 6.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 CH PF00307.31 GAM27243.1 - 2.4e-15 56.7 0.1 5.5e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain RA PF00788.23 GAM27243.1 - 5.3e-05 23.8 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain CH_2 PF06294.11 GAM27243.1 - 0.11 12.6 0.0 0.63 10.2 0.0 2.1 2 0 0 2 2 2 0 CH-like domain in sperm protein SR-25 PF10500.9 GAM27244.1 - 0.0046 16.6 1.9 0.007 16.0 1.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Serglycin PF04360.12 GAM27244.1 - 0.09 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Serglycin DUF3446 PF11928.8 GAM27244.1 - 0.2 12.0 8.4 0.077 13.3 3.2 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain RhoGEF PF00621.20 GAM27245.1 - 9.6e-39 133.5 0.7 9.6e-39 133.5 0.7 2.0 3 0 0 3 3 3 1 RhoGEF domain zinc_ribbon_2 PF13240.6 GAM27245.1 - 0.00011 21.8 5.3 0.00023 20.7 5.3 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 GAM27245.1 - 0.00022 21.2 1.7 0.00052 20.0 1.7 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 GAM27245.1 - 0.0015 17.9 5.0 0.0023 17.3 4.2 1.8 2 0 0 2 2 2 1 zinc-ribbon domain Nudix_N_2 PF14803.6 GAM27245.1 - 0.73 9.8 2.5 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_15 PF17032.5 GAM27245.1 - 1.5 9.7 6.6 1.1 10.1 4.0 2.2 2 0 0 2 2 2 0 zinc-ribbon family zf-RanBP PF00641.18 GAM27245.1 - 1.8 7.9 9.8 3.6 7.0 9.8 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-tcix PF14952.6 GAM27245.1 - 2.3 7.9 5.2 4.9 6.8 5.2 1.5 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding D5_N PF08706.11 GAM27245.1 - 5.8 7.2 8.2 14 5.9 8.2 1.6 1 0 0 1 1 1 0 D5 N terminal like Synaptobrevin PF00957.21 GAM27246.1 - 2.1e-30 104.3 2.6 3.2e-30 103.8 2.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAM27246.1 - 3.2e-25 88.0 0.2 7.3e-25 86.8 0.2 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain SRP-alpha_N PF04086.13 GAM27246.1 - 0.06 13.3 2.6 0.065 13.1 0.8 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Mpv17_PMP22 PF04117.12 GAM27248.1 - 1.7e-05 24.9 0.0 4.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Lactamase_B_2 PF12706.7 GAM27249.1 - 1.1e-18 67.5 0.0 4.5e-15 55.7 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 GAM27249.1 - 2.3e-09 36.8 0.1 5.6e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 GAM27249.1 - 0.006 16.6 0.1 0.016 15.2 0.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Dicty_REP PF05086.12 GAM27249.1 - 0.019 13.0 14.0 0.029 12.4 14.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 GAM27249.1 - 0.18 11.8 19.3 0.37 10.8 19.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein RNA_pol_Rpc4 PF05132.14 GAM27249.1 - 3.2 8.2 8.0 4.4 7.7 3.9 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Eapp_C PF10238.9 GAM27249.1 - 5 7.2 10.8 7.9 6.5 0.5 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Menin PF05053.13 GAM27249.1 - 7.7 4.7 8.6 13 4.0 8.6 1.2 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 GAM27249.1 - 9.1 4.9 6.2 6.9 5.3 4.1 1.7 2 0 0 2 2 2 0 Presenilin FH2 PF02181.23 GAM27250.1 - 1.3e-54 185.8 8.5 3.3e-54 184.4 0.0 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain DUF3361 PF11841.8 GAM27250.1 - 3.6e-07 30.3 0.0 9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Drf_FH3 PF06367.16 GAM27250.1 - 0.003 17.2 2.3 0.003 17.2 2.3 2.0 2 0 0 2 2 2 1 Diaphanous FH3 Domain TFA2_Winged_2 PF18121.1 GAM27250.1 - 0.029 14.0 0.5 3.3 7.5 0.0 3.4 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 NADH-u_ox-rdase PF10785.9 GAM27250.1 - 0.12 13.0 0.1 0.35 11.6 0.1 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Ax_dynein_light PF10211.9 GAM27250.1 - 1.3 8.9 16.4 0.18 11.7 7.7 2.5 2 0 0 2 2 2 0 Axonemal dynein light chain Mito_carr PF00153.27 GAM27251.1 - 4e-74 244.6 1.5 7.7e-24 83.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 GAM27251.1 - 0.0014 18.8 0.0 5 7.4 0.0 3.3 3 0 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase tRNA-synt_1e PF01406.19 GAM27252.1 - 1.7e-103 346.2 0.8 2.9e-103 345.4 0.8 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAM27252.1 - 5.4e-10 38.6 0.8 0.00033 19.5 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 GAM27252.1 - 0.0081 16.6 0.0 0.025 15.1 0.0 1.9 1 0 0 1 1 1 1 DALR domain K_channel_TID PF07941.11 GAM27252.1 - 0.012 16.1 5.6 0.029 14.8 5.6 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain tRNA-synt_1f PF01921.18 GAM27252.1 - 0.034 13.1 0.1 0.4 9.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) Ribonuc_P_40 PF08584.11 GAM27252.1 - 0.51 9.6 9.3 6.2 6.0 0.2 2.7 2 2 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit Hydin_ADK PF17213.3 GAM27252.1 - 5.6 7.2 7.5 12 6.1 7.5 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CCDC53 PF10152.9 GAM27252.1 - 8.2 6.8 11.3 0.82 10.1 6.3 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex ABC_tran PF00005.27 GAM27253.1 - 1.5e-28 100.0 0.1 2.9e-28 99.1 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAM27253.1 - 5.2e-14 52.1 32.4 1.2e-13 51.0 32.4 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAM27253.1 - 9.5e-08 32.2 0.1 5e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 GAM27253.1 - 0.003 17.5 0.1 0.0071 16.3 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 GAM27253.1 - 0.0096 15.7 0.0 4.2 7.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 GAM27253.1 - 0.017 15.6 0.2 0.056 13.9 0.2 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAM27253.1 - 0.033 14.5 0.0 0.084 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAM27253.1 - 0.068 12.4 0.1 0.16 11.2 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 GAM27253.1 - 0.077 13.1 0.1 0.27 11.3 0.1 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 GAM27253.1 - 0.097 11.8 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 GAM27253.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 GAM27253.1 - 0.12 11.8 0.5 15 5.0 0.2 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 GAM27254.1 - 1.1e-27 97.3 0.0 2e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 GAM27254.1 - 9.7e-20 70.9 38.5 2.7e-19 69.5 38.1 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 GAM27254.1 - 1.8e-14 54.2 1.4 7.4e-10 39.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 GAM27254.1 - 0.00043 20.2 0.0 0.0016 18.4 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain SMC_N PF02463.19 GAM27254.1 - 0.0008 18.9 0.7 0.057 12.8 0.1 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAM27254.1 - 0.00083 19.2 2.2 0.044 13.5 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain DUF4162 PF13732.6 GAM27254.1 - 0.059 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) AAA_23 PF13476.6 GAM27254.1 - 0.57 10.6 3.9 0.4 11.1 1.9 1.8 1 1 0 1 1 1 0 AAA domain FNIP PF05725.12 GAM27256.1 - 2.2e-61 203.8 31.0 2e-13 50.3 0.6 11.9 7 2 6 14 14 14 12 FNIP Repeat DUF1769 PF08588.10 GAM27256.1 - 3.7e-05 23.8 0.5 36 4.7 0.0 5.9 6 0 0 6 6 6 3 Protein of unknown function (DUF1769) PHD PF00628.29 GAM27257.1 - 6.3e-13 48.4 23.8 2.7e-08 33.6 8.6 2.5 2 0 0 2 2 2 2 PHD-finger FHA PF00498.26 GAM27257.1 - 1.3e-07 31.9 0.1 3e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 FHA domain zf-HC5HC2H PF13771.6 GAM27257.1 - 1.6e-06 28.3 9.6 0.00068 19.8 0.6 2.9 2 0 0 2 2 2 2 PHD-like zinc-binding domain PHD_2 PF13831.6 GAM27257.1 - 0.0017 17.8 2.2 0.0017 17.8 2.2 2.6 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H_2 PF13832.6 GAM27257.1 - 0.0036 17.5 10.6 0.1 12.8 2.7 2.6 2 0 0 2 2 2 2 PHD-zinc-finger like domain MFS_1 PF07690.16 GAM27258.1 - 2.1e-32 112.5 25.3 1.3e-25 90.1 5.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM27258.1 - 7.2e-11 41.6 6.0 7.2e-11 41.6 6.0 2.8 3 1 1 4 4 4 1 Sugar (and other) transporter GRP PF07172.11 GAM27258.1 - 0.028 15.1 10.4 2.9 8.7 5.8 3.5 3 0 0 3 3 3 0 Glycine rich protein family DUF5489 PF17592.2 GAM27258.1 - 0.067 13.7 1.1 1.3 9.6 0.4 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5489) MNHE PF01899.16 GAM27258.1 - 0.67 9.7 7.3 3.4 7.4 0.1 3.2 2 1 1 3 3 3 0 Na+/H+ ion antiporter subunit Peptidase_M41 PF01434.18 GAM27259.1 - 4.6e-65 219.0 0.1 2.1e-64 216.9 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 GAM27259.1 - 2.3e-43 147.8 0.0 7.6e-43 146.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM27259.1 - 5e-12 45.4 0.1 1.3e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAM27259.1 - 0.00066 19.7 0.0 0.004 17.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM27259.1 - 0.0027 18.0 0.2 0.31 11.3 0.1 3.0 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 GAM27259.1 - 0.0085 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain FtsH_ext PF06480.15 GAM27259.1 - 0.01 16.2 5.0 0.22 11.9 0.0 3.9 4 0 0 4 4 4 0 FtsH Extracellular AAA_16 PF13191.6 GAM27259.1 - 0.011 16.1 0.3 0.24 11.8 0.2 2.6 1 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 GAM27259.1 - 0.012 15.8 0.1 0.056 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 GAM27259.1 - 0.021 14.6 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Presenilin PF01080.17 GAM27259.1 - 0.035 12.9 1.8 3.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Presenilin AAA_2 PF07724.14 GAM27259.1 - 0.053 13.6 2.1 0.074 13.2 0.0 2.3 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 GAM27259.1 - 0.057 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAM27259.1 - 0.062 13.3 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAM27259.1 - 0.064 13.0 0.5 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAM27259.1 - 0.11 11.9 0.2 0.22 10.9 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI YtxH PF12732.7 GAM27259.1 - 0.13 12.8 2.0 0.34 11.5 0.2 2.5 2 0 0 2 2 2 0 YtxH-like protein DUF3464 PF11947.8 GAM27259.1 - 0.19 11.5 2.2 0.55 10.0 2.3 1.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 FAM176 PF14851.6 GAM27259.1 - 0.28 10.8 4.9 0.55 9.9 4.9 1.5 1 0 0 1 1 1 0 FAM176 family AAR2 PF05282.11 GAM27259.1 - 0.39 10.1 6.4 0.89 8.9 0.1 2.3 2 0 0 2 2 2 0 AAR2 protein CENP-B_dimeris PF09026.10 GAM27259.1 - 1.6 9.2 7.0 3.4 8.1 7.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Afi1 PF07792.12 GAM27259.1 - 8.9 6.8 11.4 19 5.8 11.4 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Oxysterol_BP PF01237.18 GAM27260.1 - 1.6e-52 178.6 0.9 2.9e-52 177.8 0.9 1.4 1 1 0 1 1 1 1 Oxysterol-binding protein Pkinase PF00069.25 GAM27261.1 - 1.4e-63 214.7 0.0 1.4e-63 214.7 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27261.1 - 4.9e-24 85.0 0.0 4.9e-24 85.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase TFIIA PF03153.13 GAM27261.1 - 0.00013 22.1 32.6 0.00019 21.6 32.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 GAM27261.1 - 4.9 5.3 31.3 6.4 4.9 31.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DLH PF01738.18 GAM27262.1 - 2e-39 135.4 0.0 2.2e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 GAM27262.1 - 2.3e-06 27.3 0.1 0.0047 16.4 0.0 2.3 1 1 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 GAM27262.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 GAM27262.1 - 0.041 13.5 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 GAM27262.1 - 0.068 12.6 0.1 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 GAM27262.1 - 0.096 11.9 0.1 6.1 6.0 0.0 2.7 2 1 0 3 3 3 0 Serine aminopeptidase, S33 DUF2048 PF09752.9 GAM27262.1 - 0.12 11.5 0.3 0.67 9.0 0.0 1.9 2 0 0 2 2 2 0 Abhydrolase domain containing 18 AAA PF00004.29 GAM27263.1 - 1.7e-49 167.6 0.0 6.8e-37 126.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAM27263.1 - 5e-09 36.8 0.0 0.00042 20.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 GAM27263.1 - 1.7e-08 34.6 0.0 0.00013 22.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM27263.1 - 4e-08 33.6 0.5 0.0023 18.2 0.0 4.0 2 2 2 4 4 4 1 AAA domain AAA_2 PF07724.14 GAM27263.1 - 2.9e-07 30.8 0.1 1.9e-05 24.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAM27263.1 - 3.6e-07 30.7 0.1 0.025 15.0 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 GAM27263.1 - 4.2e-07 30.2 0.0 0.028 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 GAM27263.1 - 1.2e-06 28.2 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 GAM27263.1 - 9.9e-06 25.6 0.1 0.3 11.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.12 GAM27263.1 - 1.5e-05 24.8 0.0 0.0069 16.1 0.1 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 GAM27263.1 - 2.6e-05 23.8 0.0 0.0094 15.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 GAM27263.1 - 2.6e-05 24.6 0.0 0.11 12.8 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Sigma54_activat PF00158.26 GAM27263.1 - 3.4e-05 23.6 0.0 0.36 10.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 GAM27263.1 - 3.5e-05 24.3 0.2 0.058 13.9 0.1 2.6 2 0 0 2 2 2 1 ABC transporter TsaE PF02367.17 GAM27263.1 - 3.5e-05 23.8 0.0 0.52 10.3 0.0 2.9 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 GAM27263.1 - 6.1e-05 22.5 1.2 0.0023 17.3 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 GAM27263.1 - 7.4e-05 22.1 0.0 0.0088 15.3 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 GAM27263.1 - 0.00011 21.9 0.1 0.12 12.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAM27263.1 - 0.00026 21.3 0.0 0.18 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAM27263.1 - 0.00044 20.0 0.0 0.19 11.4 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 GAM27263.1 - 0.00068 19.0 0.2 0.096 12.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 GAM27263.1 - 0.00097 19.1 3.3 1.6 8.6 0.0 3.6 4 0 0 4 4 3 1 NACHT domain AAA_3 PF07726.11 GAM27263.1 - 0.0017 18.2 0.0 0.35 10.7 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 GAM27263.1 - 0.0023 17.7 0.1 0.0085 15.9 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 ATPase PF06745.13 GAM27263.1 - 0.0025 17.2 0.4 0.037 13.4 0.0 2.6 2 1 0 2 2 2 1 KaiC Sigma54_activ_2 PF14532.6 GAM27263.1 - 0.0036 17.4 0.0 3.9 7.6 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain DUF815 PF05673.13 GAM27263.1 - 0.0052 16.0 0.1 0.24 10.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 GAM27263.1 - 0.0098 15.5 0.9 0.95 9.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GAM27263.1 - 0.011 16.2 0.0 6.4 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAM27263.1 - 0.018 15.5 0.1 0.44 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAM27263.1 - 0.019 14.7 0.5 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 GAM27263.1 - 0.02 14.6 0.1 1.8 8.2 0.1 2.6 2 0 0 2 2 2 0 Cytidylate kinase TniB PF05621.11 GAM27263.1 - 0.032 13.6 0.2 4.7 6.6 0.0 3.2 2 1 1 3 3 3 0 Bacterial TniB protein SKI PF01202.22 GAM27263.1 - 0.051 13.7 0.1 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase CPT PF07931.12 GAM27263.1 - 0.062 13.1 0.7 5.3 6.8 0.0 3.1 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 GAM27263.1 - 0.064 12.4 0.2 3 7.0 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 GAM27263.1 - 0.079 12.7 0.1 0.65 9.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 GAM27263.1 - 0.089 13.1 0.3 0.7 10.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 GAM27263.1 - 0.091 12.4 0.0 2.7 7.6 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.16 GAM27263.1 - 0.093 12.2 0.1 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 GAM27263.1 - 0.12 11.4 0.0 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein KTI12 PF08433.10 GAM27263.1 - 0.13 11.7 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 GAM27263.1 - 0.14 11.4 0.5 2.2 7.4 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 GAM27263.1 - 0.15 12.0 0.2 3.5 7.5 0.0 2.7 2 1 1 3 3 2 0 NTPase HMG_box PF00505.19 GAM27264.1 - 3.6e-17 62.5 14.1 1.1e-13 51.3 2.7 3.6 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 GAM27264.1 - 3.3e-10 40.4 22.1 1.9e-07 31.6 1.1 3.7 3 1 0 3 3 3 2 HMG-box domain Protamine_like PF06382.11 GAM27264.1 - 0.00021 21.5 7.4 0.00074 19.7 0.3 2.7 2 1 1 3 3 3 2 Protamine and protamine like DUF2288 PF10052.9 GAM27264.1 - 0.008 16.2 3.4 0.02 15.0 3.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2288) YABBY PF04690.13 GAM27264.1 - 0.042 14.4 0.8 0.042 14.4 0.8 2.8 1 1 2 3 3 3 0 YABBY protein RBD PF02196.15 GAM27264.1 - 0.053 13.6 0.4 7.5 6.7 0.0 3.0 3 0 0 3 3 3 0 Raf-like Ras-binding domain Suc_Fer-like PF06999.12 GAM27265.1 - 2.2e-39 135.4 0.0 2.6e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like NPR1_like_C PF12313.8 GAM27265.1 - 0.049 13.1 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal Fer2_2 PF01799.20 GAM27265.1 - 0.11 12.5 0.1 19 5.4 0.0 2.4 2 0 0 2 2 2 0 [2Fe-2S] binding domain Gly_kinase PF02595.15 GAM27266.1 - 4.8e-100 335.1 0.5 5.7e-100 334.9 0.5 1.0 1 0 0 1 1 1 1 Glycerate kinase family MPP6 PF10175.9 GAM27267.1 - 4.7e-14 53.0 19.7 3.5e-13 50.2 19.7 2.0 1 1 0 1 1 1 1 M-phase phosphoprotein 6 LPD25 PF18840.1 GAM27267.1 - 0.026 15.1 0.8 0.06 13.9 0.1 2.0 2 1 0 2 2 2 0 Large polyvalent protein associated domain 25 DUF21 PF01595.20 GAM27268.1 - 1.6e-36 125.6 1.9 2.4e-36 125.1 1.9 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GAM27268.1 - 4.8e-06 26.9 0.9 0.038 14.5 0.9 2.6 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 GAM27268.1 - 0.0016 18.4 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain ELL PF10390.9 GAM27268.1 - 0.02 14.4 0.6 0.034 13.6 0.6 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF4551 PF15087.6 GAM27268.1 - 0.47 9.2 3.7 0.74 8.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Glyco_hydro_16 PF00722.21 GAM27269.1 - 9.9e-08 31.6 0.3 2.7e-07 30.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Ribosomal_S4e PF00900.20 GAM27270.1 - 2e-28 98.1 0.1 3.5e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 GAM27270.1 - 3.7e-18 65.3 7.3 7.7e-18 64.3 7.3 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 GAM27270.1 - 1e-17 63.5 0.1 1.6e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 GAM27270.1 - 5.1e-11 42.1 0.1 9e-11 41.3 0.1 1.4 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 GAM27270.1 - 3.2e-05 23.7 1.2 9.4e-05 22.2 0.1 2.4 2 0 0 2 2 2 1 KOW motif Pkinase_Tyr PF07714.17 GAM27271.1 - 2.5e-64 217.0 0.0 3.6e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM27271.1 - 6.6e-60 202.7 0.0 9.6e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 GAM27271.1 - 2.5e-10 40.3 7.5 2.5e-10 40.3 7.5 2.8 2 0 0 2 2 2 1 IPT/TIG domain SR-25 PF10500.9 GAM27271.1 - 0.0093 15.6 4.9 0.014 15.0 4.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein APH PF01636.23 GAM27271.1 - 0.022 14.7 0.3 0.043 13.7 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family TCP PF03634.13 GAM27271.1 - 2.1 8.9 5.0 3.5 8.2 5.0 1.2 1 0 0 1 1 1 0 TCP family transcription factor Fumble PF03630.14 GAM27272.1 - 1.1e-85 287.7 0.4 1.3e-85 287.5 0.4 1.0 1 0 0 1 1 1 1 Fumble RNA_pol_Rpc4 PF05132.14 GAM27273.1 - 0.029 14.8 0.3 0.029 14.8 0.3 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Op_neuropeptide PF08035.11 GAM27274.1 - 0.03 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Opioids neuropeptide Transglut_core PF01841.19 GAM27275.1 - 9.9e-12 45.3 0.0 1.9e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily BAR PF03114.18 GAM27275.1 - 0.68 9.5 4.9 1.2 8.8 2.8 2.3 2 1 0 2 2 2 0 BAR domain DUF829 PF05705.14 GAM27276.1 - 9.8e-38 130.4 1.2 3.2e-37 128.7 1.2 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) FSH1 PF03959.13 GAM27276.1 - 0.0027 17.4 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF4509 PF14970.6 GAM27276.1 - 0.07 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Peptidase_S9 PF00326.21 GAM27276.1 - 0.077 12.5 1.7 0.079 12.4 0.2 1.7 3 0 0 3 3 3 0 Prolyl oligopeptidase family NDK PF00334.19 GAM27277.1 - 2.6e-35 121.4 0.0 3e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Vps54 PF07928.12 GAM27278.1 - 5.2e-44 149.9 1.6 2.7e-43 147.6 0.3 2.9 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 GAM27278.1 - 4.6e-15 55.7 1.4 4.6e-15 55.7 1.4 2.6 4 0 0 4 4 4 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 GAM27278.1 - 6.9e-05 23.0 1.7 6.9e-05 23.0 1.7 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 GAM27278.1 - 0.0016 17.5 3.1 0.0016 17.5 3.1 2.2 2 0 0 2 2 2 1 Vps53-like, N-terminal EPL1 PF10513.9 GAM27278.1 - 0.25 11.7 8.7 3.1 8.2 2.0 2.8 2 0 0 2 2 2 0 Enhancer of polycomb-like tRNA_anti-codon PF01336.25 GAM27279.1 - 0.00051 20.0 0.0 0.00094 19.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 GAM27279.1 - 0.0092 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 CH PF00307.31 GAM27280.1 - 1.4e-30 105.7 1.1 1.7e-15 57.2 0.0 3.7 4 0 0 4 4 4 2 Calponin homology (CH) domain RasGAP PF00616.19 GAM27280.1 - 1.2e-28 100.2 1.3 1.2e-28 100.2 1.3 3.0 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase USP7_C2 PF14533.6 GAM27281.1 - 0.047 13.4 0.1 0.075 12.7 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal BAR PF03114.18 GAM27281.1 - 0.067 12.8 7.7 7 6.2 7.7 2.2 1 1 0 1 1 1 0 BAR domain FKBP_N PF01346.18 GAM27281.1 - 0.087 13.8 0.8 0.087 13.8 0.8 2.4 4 0 0 4 4 4 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase UPF0242 PF06785.11 GAM27281.1 - 0.82 9.7 8.8 10 6.2 8.8 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Adap_comp_sub PF00928.21 GAM27282.1 - 1.1e-88 297.1 0.0 1.5e-88 296.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAM27282.1 - 2.5e-10 40.4 1.7 4.8e-10 39.5 1.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LRR_4 PF12799.7 GAM27282.1 - 0.033 14.6 3.2 0.94 10.0 0.1 4.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Tub_N PF16322.5 GAM27285.1 - 4 7.8 13.2 7.8 6.8 13.2 1.7 1 1 0 1 1 1 0 Tubby N-terminal Tmemb_cc2 PF10267.9 GAM27285.1 - 6.2 5.8 6.6 8.2 5.4 6.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DnaJ_C PF01556.18 GAM27286.1 - 1.9e-40 138.3 1.7 2.6e-40 137.9 1.7 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAM27286.1 - 2.1e-27 95.0 3.2 3.7e-27 94.2 3.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAM27286.1 - 9e-17 61.2 18.5 1.6e-16 60.4 18.5 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAM27286.1 - 0.0011 18.9 9.0 0.15 12.0 1.1 2.7 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 GAM27286.1 - 0.011 15.8 9.0 0.91 9.6 0.3 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF971 PF06155.12 GAM27286.1 - 0.2 12.3 3.5 13 6.5 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF971) Cytochrome_C7 PF14522.6 GAM27286.1 - 1.3 9.1 12.7 7.3 6.7 12.0 2.4 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-RING_10 PF16685.5 GAM27286.1 - 7 6.9 10.2 0.43 10.7 2.7 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 BCIP PF13862.6 GAM27289.1 - 3.1e-35 121.9 3.3 3.1e-35 121.9 3.3 3.6 2 2 0 2 2 1 1 p21-C-terminal region-binding protein Porph_ging PF09697.10 GAM27289.1 - 0.044 14.3 0.0 0.044 14.3 0.0 3.8 2 1 1 3 3 3 0 Protein of unknown function (Porph_ging) SPICE PF15678.5 GAM27289.1 - 0.23 10.8 20.7 0.42 9.9 20.7 1.4 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression Ndc1_Nup PF09531.10 GAM27289.1 - 0.24 10.1 5.3 0.26 9.9 5.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup V_ATPase_I PF01496.19 GAM27289.1 - 0.26 9.1 10.4 0.45 8.4 10.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cwf_Cwc_15 PF04889.12 GAM27289.1 - 0.34 10.6 26.5 0.053 13.3 21.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CNDH2_C PF16858.5 GAM27289.1 - 0.36 10.6 19.1 0.061 13.2 15.1 1.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SprA-related PF12118.8 GAM27289.1 - 1.9 7.6 29.6 3.6 6.6 29.6 1.4 1 0 0 1 1 1 0 SprA-related family DNA_pol_phi PF04931.13 GAM27289.1 - 3.2 5.7 18.7 5.8 4.9 18.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi BAF1_ABF1 PF04684.13 GAM27289.1 - 4.5 6.2 28.2 1.2 8.1 24.6 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor GEMIN8 PF15348.6 GAM27289.1 - 5 7.4 16.9 9.2 6.5 14.7 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 SID-1_RNA_chan PF13965.6 GAM27289.1 - 5.5 5.3 10.2 8.3 4.7 10.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Myb_DNA-binding PF00249.31 GAM27291.1 - 1.3e-25 89.3 6.4 1.3e-15 57.3 0.4 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM27291.1 - 1.1e-19 70.4 0.8 4.5e-15 55.7 0.2 4.0 3 1 1 4 4 4 2 Myb-like DNA-binding domain SLIDE PF09111.10 GAM27291.1 - 0.4 10.7 0.0 0.4 10.7 0.0 4.3 3 2 1 5 5 5 0 SLIDE DUF4326 PF14216.6 GAM27292.1 - 1.5e-14 54.5 0.1 1.9e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) Arf PF00025.21 GAM27293.1 - 3.1e-55 186.3 0.0 3.7e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAM27293.1 - 4.9e-09 35.9 0.0 7.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 GAM27293.1 - 8.9e-09 35.6 0.0 1.8e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM27293.1 - 7.5e-05 22.4 0.0 9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAM27293.1 - 0.00013 21.4 0.1 0.00038 19.9 0.1 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM27293.1 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAM27293.1 - 0.00042 19.6 0.6 0.13 11.4 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit AAA_24 PF13479.6 GAM27293.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAM27293.1 - 0.053 13.4 0.5 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 GAM27293.1 - 0.074 13.4 0.1 0.12 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAM27293.1 - 0.077 13.3 0.0 0.43 10.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM27293.1 - 0.1 13.1 0.0 0.15 12.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAM27293.1 - 0.14 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain MWFE PF15879.5 GAM27294.1 - 3.5e-13 49.5 0.5 5.1e-13 49.0 0.0 1.4 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase MWFE subunit Pro_isomerase PF00160.21 GAM27295.1 - 7.6e-49 166.0 0.1 9e-49 165.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Transglut_core PF01841.19 GAM27296.1 - 3.9e-13 49.8 0.0 8.3e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Ferrochelatase PF00762.19 GAM27297.1 - 8e-109 363.5 0.0 9.7e-109 363.3 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase Coprogen_oxidas PF01218.18 GAM27298.1 - 4.6e-102 340.7 0.1 5.3e-102 340.5 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase CTU2 PF10288.9 GAM27299.1 - 7.1e-10 39.1 16.3 1.6e-09 38.0 16.3 1.7 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 PAPS_reduct PF01507.19 GAM27299.1 - 0.017 15.1 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family FERM_M PF00373.18 GAM27300.1 - 6.6e-23 81.4 0.7 1.4e-22 80.3 0.1 1.8 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 GAM27300.1 - 0.00056 19.8 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain DAAD PF18752.1 GAM27300.1 - 0.042 13.7 0.6 0.71 9.7 0.0 2.1 1 1 1 2 2 2 0 Dictyosteliid AID/APOBEC-like Deaminase DUF4504 PF14953.6 GAM27301.1 - 1.3e-07 31.3 0.0 3.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) Ras PF00071.22 GAM27302.1 - 1.9e-28 99.1 0.3 2.7e-28 98.6 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM27302.1 - 8.2e-19 68.0 0.0 2e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM27302.1 - 0.00012 21.6 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family CENP-M PF11111.8 GAM27302.1 - 0.062 12.5 0.3 0.14 11.3 0.3 1.6 1 0 0 1 1 1 0 Centromere protein M (CENP-M) EF-hand_1 PF00036.32 GAM27303.1 - 6.1e-37 122.4 10.7 2.6e-09 36.0 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAM27303.1 - 1.5e-32 111.9 1.8 9.8e-16 58.0 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAM27303.1 - 3.5e-28 97.2 7.4 5.3e-14 51.8 0.7 3.5 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 GAM27303.1 - 1.9e-27 92.8 4.4 1.6e-07 30.7 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAM27303.1 - 8.4e-25 85.1 6.9 1.6e-05 24.2 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAM27303.1 - 8.5e-13 48.4 0.0 2.1e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAM27303.1 - 2.4e-09 37.5 0.0 0.0008 19.7 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAM27303.1 - 2.3e-08 33.9 0.5 0.0029 17.5 0.2 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 GAM27303.1 - 2e-07 31.1 1.7 0.0069 16.6 0.1 3.6 1 1 3 4 4 4 3 Dockerin type I domain UPF0154 PF03672.13 GAM27303.1 - 2.2e-06 27.6 0.0 0.015 15.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 GAM27303.1 - 5.4e-06 27.2 0.0 0.0089 16.9 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 GAM27303.1 - 0.00034 20.6 0.4 0.49 10.3 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein EFhand_Ca_insen PF08726.10 GAM27303.1 - 0.0035 17.4 0.1 0.0068 16.5 0.1 1.6 1 0 0 1 1 1 1 Ca2+ insensitive EF hand SurA_N_3 PF13624.6 GAM27303.1 - 0.051 13.4 0.2 2.9 7.6 0.1 2.0 1 1 0 2 2 2 0 SurA N-terminal domain SurA_N_2 PF13623.6 GAM27303.1 - 0.056 13.3 1.1 0.83 9.5 0.3 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 GAM27303.1 - 0.058 13.5 0.2 0.52 10.5 0.1 2.1 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Phage_TAC_12 PF12363.8 GAM27303.1 - 0.059 13.8 0.7 5.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC CtsR_C PF17727.1 GAM27303.1 - 0.071 13.3 0.3 4.1 7.6 0.0 2.7 3 0 0 3 3 3 0 CtsR C-terminal dimerization domain TetR_C_7 PF14246.6 GAM27303.1 - 0.08 13.0 0.0 7.8 6.6 0.0 2.2 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain DUF3008 PF11450.8 GAM27303.1 - 0.087 13.0 0.4 2.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) DUF3349 PF11829.8 GAM27303.1 - 0.089 13.6 0.2 23 5.8 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) DUF5132 PF17195.4 GAM27303.1 - 0.096 12.8 0.7 5.5 7.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RNA_pol_Rpb4 PF03874.16 GAM27303.1 - 0.11 12.9 0.6 6.2 7.2 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 RNB PF00773.19 GAM27303.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.3 1 1 0 1 1 1 0 RNB domain Carb_kinase PF01256.17 GAM27304.1 - 4.1e-51 173.8 0.0 6.2e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 GAM27304.1 - 0.00059 19.3 0.4 0.0012 18.3 0.4 1.6 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 GAM27304.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase SMC_N PF02463.19 GAM27306.1 - 8.6e-20 71.1 19.7 9.6e-19 67.7 19.7 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM27306.1 - 6.9e-17 62.6 3.2 6.9e-17 62.6 3.2 5.8 4 2 1 5 5 3 1 AAA domain AAA_15 PF13175.6 GAM27306.1 - 4.2e-09 36.6 10.2 4.2e-09 36.6 10.2 3.0 2 2 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 GAM27306.1 - 8.2e-07 29.1 7.1 0.0011 18.8 0.0 3.2 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAM27306.1 - 0.0009 18.9 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2205 PF10224.9 GAM27306.1 - 0.0026 17.7 3.3 0.0026 17.7 3.3 5.6 6 1 1 7 7 7 1 Short coiled-coil protein BRE1 PF08647.11 GAM27306.1 - 0.0041 17.2 10.7 0.0041 17.2 10.7 7.0 7 1 0 8 8 7 1 BRE1 E3 ubiquitin ligase AAA_27 PF13514.6 GAM27306.1 - 0.036 13.7 0.0 0.036 13.7 0.0 5.1 4 2 2 6 6 6 0 AAA domain AAA_25 PF13481.6 GAM27306.1 - 0.039 13.5 0.5 0.38 10.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAM27306.1 - 0.44 11.0 0.1 0.44 11.0 0.1 5.6 4 2 0 5 5 2 0 ABC transporter HSBP1 PF06825.12 GAM27306.1 - 1.5 8.8 18.4 4.6 7.2 0.0 6.3 7 0 0 7 7 7 0 Heat shock factor binding protein 1 AAA_16 PF13191.6 GAM27306.1 - 2.1 8.7 4.8 2.1 8.7 0.0 3.2 4 0 0 4 4 4 0 AAA ATPase domain FUSC PF04632.12 GAM27306.1 - 9.9 4.6 11.1 0.28 9.7 2.5 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Ras PF00071.22 GAM27307.1 - 3.8e-49 166.4 0.0 4.8e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM27307.1 - 1.6e-32 112.2 0.0 2.2e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM27307.1 - 1.8e-11 43.8 0.0 2.2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM27307.1 - 0.00012 22.2 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAM27307.1 - 0.0024 17.3 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM27307.1 - 0.0037 16.8 0.0 0.018 14.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM27307.1 - 0.037 13.9 0.1 0.33 10.8 0.0 2.1 1 1 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 GAM27307.1 - 0.061 13.6 0.1 0.33 11.2 0.0 1.9 1 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 GAM27307.1 - 0.099 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CN_hydrolase PF00795.22 GAM27308.1 - 5.7e-17 61.9 0.0 9.9e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Knl1_RWD_C PF18210.1 GAM27308.1 - 0.025 15.0 1.1 0.059 13.8 0.1 2.1 2 0 0 2 2 2 0 Knl1 RWD C-terminal domain Peptidase_S8 PF00082.22 GAM27310.1 - 0.0093 15.3 0.5 0.018 14.3 0.5 1.5 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 GAM27311.1 - 1.6e-26 93.3 0.1 1.9e-26 93.1 0.1 1.1 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF5609 PF18429.1 GAM27311.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5609) FNIP PF05725.12 GAM27312.1 - 3.2e-51 171.2 10.6 6.6e-12 45.4 0.1 8.9 5 2 2 9 9 9 8 FNIP Repeat PNRC PF15365.6 GAM27312.1 - 1.1 9.1 4.7 0.31 10.9 0.3 2.3 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif I_LWEQ PF01608.17 GAM27313.1 - 2.8e-42 144.5 192.4 1.3e-40 139.1 15.7 17.2 5 4 12 19 19 19 9 I/LWEQ domain FERM_f0 PF16511.5 GAM27313.1 - 1.8e-26 92.3 0.0 7.3e-22 77.5 0.0 3.0 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 GAM27313.1 - 3.2e-25 88.8 3.3 8.8e-25 87.4 0.6 3.3 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 GAM27313.1 - 8.9e-12 44.8 0.1 8.9e-11 41.6 0.0 2.7 2 0 0 2 2 2 1 FERM N-terminal domain VBS PF08913.10 GAM27313.1 - 1.7e-05 25.2 2.3 1.7e-05 25.2 2.3 11.5 12 2 2 14 14 14 4 Vinculin Binding Site IRS PF02174.17 GAM27313.1 - 6.2e-05 22.8 0.0 0.00021 21.1 0.0 1.9 1 0 0 1 1 1 1 PTB domain (IRS-1 type) YukD PF08817.10 GAM27313.1 - 0.00017 22.2 0.0 0.001 19.7 0.0 2.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.8 GAM27313.1 - 0.005 16.7 0.1 0.029 14.2 0.1 2.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PID PF00640.23 GAM27313.1 - 0.008 16.2 2.4 0.057 13.5 0.0 3.8 3 0 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) ACBP PF00887.19 GAM27313.1 - 0.071 13.3 3.0 0.065 13.5 0.4 2.4 2 0 0 2 2 2 0 Acyl CoA binding protein NAD_binding_1 PF00175.21 GAM27313.1 - 0.079 13.6 0.0 0.55 10.9 0.0 2.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain SipA_VBS PF17985.1 GAM27313.1 - 0.16 11.9 12.5 1.8 8.6 0.8 5.1 5 0 0 5 5 5 0 SipA vinculin binding site Sec7 PF01369.20 GAM27314.1 - 1.5e-53 181.2 4.5 1.5e-53 181.2 4.5 2.8 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 GAM27314.1 - 1.5e-34 119.2 2.9 1.5e-34 119.2 2.9 5.1 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAM27314.1 - 9.5e-29 99.1 9.4 1.7e-28 98.3 0.6 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 GAM27314.1 - 8.7e-27 93.9 1.4 8.7e-27 93.9 1.4 4.3 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 TFCD_C PF12612.8 GAM27314.1 - 0.26 11.1 5.2 0.62 9.9 0.2 3.8 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal FA_desaturase PF00487.24 GAM27316.1 - 1.4e-34 120.1 22.5 2e-34 119.6 20.3 1.9 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 GAM27316.1 - 2.1e-25 88.6 0.4 5.4e-23 80.9 0.0 3.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 GAM27316.1 - 0.016 15.4 0.1 0.045 13.9 0.1 1.7 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone Dicty_CAR PF05462.11 GAM27317.1 - 2.2e-152 506.5 25.2 2.7e-152 506.2 25.2 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 GAM27317.1 - 2.1e-12 46.8 20.7 3e-12 46.4 20.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1129 PF06570.11 GAM27317.1 - 0.0083 15.6 0.4 0.0083 15.6 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) tRNA-synt_1b PF00579.25 GAM27318.1 - 2.1e-70 237.4 0.0 3.2e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 GAM27318.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 S4 domain DUF553 PF04473.12 GAM27318.1 - 0.095 12.2 0.0 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 Transglutaminase-like domain STN1_2 PF09170.10 GAM27318.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 FNIP PF05725.12 GAM27319.1 - 5.1e-92 301.8 35.5 3.2e-13 49.6 2.9 11.7 6 2 6 13 13 13 13 FNIP Repeat Glyco_hydro_65C PF03633.15 GAM27319.1 - 0.02 14.8 0.3 40 4.2 0.0 5.3 6 0 0 6 6 6 0 Glycosyl hydrolase family 65, C-terminal domain PWI PF01480.17 GAM27320.1 - 2.9e-15 56.4 2.8 4.3e-15 55.8 0.7 2.3 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 GAM27320.1 - 5.7e-10 38.9 0.0 1.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4107 PF13389.6 GAM27320.1 - 0.25 11.5 2.9 8.2 6.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) Rad60-SLD PF11976.8 GAM27320.1 - 1.1 9.1 6.6 0.9 9.4 0.1 2.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like FTZ PF03867.14 GAM27320.1 - 1.3 8.5 7.2 2.3 7.7 7.2 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Xpo1 PF08389.12 GAM27321.1 - 0.038 14.0 4.3 0.061 13.4 0.5 3.5 2 1 0 2 2 2 0 Exportin 1-like protein DUF383 PF04063.14 GAM27321.1 - 0.045 13.4 1.0 0.11 12.1 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF383) UCH PF00443.29 GAM27321.1 - 0.35 10.3 3.8 19 4.6 3.8 2.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.22 GAM27322.1 - 1.2e-16 60.2 0.0 1.6e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAM27322.1 - 7.2e-05 22.8 0.0 0.00019 21.5 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 GAM27322.1 - 0.0065 16.7 0.0 0.031 14.5 0.1 1.8 1 1 1 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 GAM27322.1 - 0.018 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ACT_3 PF10000.9 GAM27322.1 - 0.18 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 ACT domain Complex1_LYR PF05347.15 GAM27323.1 - 5.3e-08 32.8 0.0 6.6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAM27323.1 - 0.058 14.1 0.0 0.064 14.0 0.0 1.1 1 0 0 1 1 1 0 Complex1_LYR-like AAA PF00004.29 GAM27324.1 - 2e-20 73.6 0.1 6.1e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM27324.1 - 0.00017 21.6 0.0 0.019 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 GAM27324.1 - 0.00017 21.3 0.2 0.00081 19.1 0.2 2.1 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 GAM27324.1 - 0.00027 20.9 0.0 0.00064 19.7 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 GAM27324.1 - 0.0016 18.2 0.0 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAM27324.1 - 0.0059 17.0 0.0 0.14 12.5 0.0 2.5 1 1 2 3 3 3 1 AAA ATPase domain Parvo_NS1 PF01057.17 GAM27324.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TIP49 PF06068.13 GAM27324.1 - 0.079 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 GAM27324.1 - 0.086 12.4 0.1 0.63 9.5 0.1 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region PPV_E1_C PF00519.17 GAM27324.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase DUF815 PF05673.13 GAM27324.1 - 0.12 11.5 0.0 0.35 10.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Ras PF00071.22 GAM27325.1 - 6.5e-42 142.9 0.0 8.9e-42 142.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM27325.1 - 6.7e-14 52.1 0.0 1.4e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 GAM27325.1 - 8.9e-06 25.7 0.0 0.1 12.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAM27325.1 - 0.00011 21.8 0.1 0.00094 18.7 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 GAM27325.1 - 0.00035 20.1 0.0 0.00053 19.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM27325.1 - 0.00067 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DNA_pol3_delta2 PF13177.6 GAM27325.1 - 0.0015 18.3 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit G-alpha PF00503.20 GAM27325.1 - 0.0048 16.1 0.1 0.24 10.5 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit NACHT PF05729.12 GAM27325.1 - 0.032 14.2 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AIG1 PF04548.16 GAM27325.1 - 0.036 13.4 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 GAM27325.1 - 0.058 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 GAM27325.1 - 0.079 12.4 0.2 1.8 7.9 0.0 2.5 2 1 1 3 3 3 0 Bacterial TniB protein NB-ARC PF00931.22 GAM27325.1 - 0.08 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 GAM27325.1 - 0.084 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF5534 PF17686.1 GAM27325.1 - 3.8 7.7 5.1 1.7 8.9 0.1 2.2 1 1 2 3 3 3 0 Family of unknown function (DUF5534) cNMP_binding PF00027.29 GAM27326.1 - 1.9e-27 95.1 0.0 4.2e-16 58.8 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lactamase_B PF00753.27 GAM27326.1 - 2.6e-09 37.4 0.0 6.3e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAM27326.1 - 2.8e-08 33.5 0.0 7.2e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAM27326.1 - 0.035 14.0 0.2 0.29 11.0 0.0 2.4 2 1 0 2 2 2 0 Beta-lactamase superfamily domain ARID PF01388.21 GAM27327.1 - 2.7e-22 79.3 0.0 1.4e-21 77.0 0.0 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain SAP30_Sin3_bdg PF13867.6 GAM27327.1 - 4.8e-16 58.8 1.0 1.2e-15 57.5 1.0 1.8 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 FKBP_C PF00254.28 GAM27328.1 - 4.9e-25 87.7 0.3 7.4e-24 83.9 0.0 2.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.23 GAM27328.1 - 5.4e-06 26.3 1.0 5.4e-06 26.3 1.0 2.3 2 0 0 2 2 2 1 WH1 domain DNA_repr_REX1B PF14966.6 GAM27328.1 - 0.00022 21.8 1.7 0.00022 21.8 1.7 4.3 3 1 1 4 4 4 1 DNA repair REX1-B VID27_PH PF17747.1 GAM27328.1 - 0.079 13.3 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 VID27 PH-like domain T3SS_needle_E PF08988.10 GAM27328.1 - 7.5 6.8 13.6 2.9 8.1 1.3 3.8 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle DUF1981 PF09324.10 GAM27329.1 - 0.037 13.9 0.9 0.055 13.3 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) GLE1 PF07817.13 GAM27329.1 - 0.16 11.1 2.9 0.19 10.9 2.9 1.1 1 0 0 1 1 1 0 GLE1-like protein Sulf_coat_C PF12193.8 GAM27330.1 - 0.086 12.9 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 Sulfolobus virus coat protein C terminal MRP-S32 PF10210.9 GAM27331.1 - 0.036 14.6 0.1 0.054 14.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 DUF4381 PF14316.6 GAM27331.1 - 0.046 14.0 0.4 0.08 13.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) P5-ATPase PF12409.8 GAM27331.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.4 2 1 1 3 3 3 0 P5-type ATPase cation transporter SfLAP PF11139.8 GAM27331.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.4 1 1 0 1 1 1 0 Sap, sulfolipid-1-addressing protein RhoGAP PF00620.27 GAM27332.1 - 7.4e-34 116.8 0.0 1.9e-33 115.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LRR_6 PF13516.6 GAM27332.1 - 1.1e-08 34.5 25.7 8.1e-06 25.5 0.1 7.2 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 GAM27332.1 - 0.0016 18.8 28.7 0.68 10.4 0.1 7.3 6 1 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM27332.1 - 0.0066 16.8 12.0 1.5 9.7 0.0 7.3 8 0 0 8 8 8 1 Leucine Rich Repeat PI3K_P85_iSH2 PF16454.5 GAM27333.1 - 1.2e-05 25.0 7.0 0.00066 19.3 7.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF745 PF05335.13 GAM27333.1 - 0.018 14.8 5.9 0.079 12.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Phage_GPL PF05926.11 GAM27333.1 - 0.038 14.0 3.0 4 7.4 0.2 2.4 2 0 0 2 2 2 0 Phage head completion protein (GPL) WXG100 PF06013.12 GAM27333.1 - 0.045 14.0 2.1 7.6 6.8 0.2 2.7 2 1 1 3 3 3 0 Proteins of 100 residues with WXG XhlA PF10779.9 GAM27333.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.9 3 0 0 3 3 3 0 Haemolysin XhlA HisKA PF00512.25 GAM27333.1 - 0.19 11.8 5.8 1.6 8.8 0.0 3.0 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF948 PF06103.11 GAM27333.1 - 0.4 11.0 4.7 4.3 7.6 0.5 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) YojJ PF10372.9 GAM27333.1 - 0.75 9.9 4.7 7.9 6.7 0.1 3.3 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus TMPIT PF07851.13 GAM27333.1 - 0.9 8.7 5.4 3.3 6.9 0.1 2.2 2 0 0 2 2 2 0 TMPIT-like protein KxDL PF10241.9 GAM27333.1 - 1 9.7 8.9 1.5 9.1 0.0 3.5 3 1 1 4 4 4 0 Uncharacterized conserved protein Laminin_II PF06009.12 GAM27333.1 - 1.3 9.0 14.5 0.05 13.6 1.7 3.0 1 1 2 3 3 3 0 Laminin Domain II PHM7_cyt PF14703.6 GAM27333.1 - 3.4 7.9 12.0 21 5.3 10.1 2.8 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Tropomyosin_1 PF12718.7 GAM27333.1 - 4.8 7.3 18.0 0.11 12.6 1.2 3.0 3 0 0 3 3 3 0 Tropomyosin like MFS_1 PF07690.16 GAM27334.1 - 4.6e-67 226.4 28.8 2.6e-44 151.6 8.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAM27334.1 - 1.9e-16 59.9 22.3 7.4e-10 38.2 6.5 2.6 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 GAM27334.1 - 1.3e-13 50.6 21.0 7.4e-12 44.9 12.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 GAM27334.1 - 2.3e-10 40.3 8.6 9.5e-08 31.7 8.6 2.2 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 GAM27334.1 - 9.6e-08 30.9 9.5 6.3e-07 28.2 7.2 2.1 1 1 1 2 2 2 2 Transmembrane secretion effector MFS_5 PF05631.14 GAM27334.1 - 3.6e-05 22.9 9.4 4.9e-05 22.4 3.0 2.5 1 1 1 2 2 2 1 Sugar-tranasporters, 12 TM LacY_symp PF01306.19 GAM27334.1 - 4.7e-05 22.3 24.9 6.3e-05 21.9 1.7 3.6 3 1 0 3 3 3 2 LacY proton/sugar symporter OATP PF03137.20 GAM27334.1 - 6.8e-05 21.4 20.5 0.03 12.6 9.7 4.1 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family NAD_binding_4 PF07993.12 GAM27335.1 - 2.2e-60 204.0 0.0 3.7e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 GAM27335.1 - 2.7e-23 82.1 0.0 7.8e-23 80.6 0.0 1.8 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.19 GAM27335.1 - 1.7e-18 66.7 0.2 4.1e-18 65.4 0.2 1.7 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 GAM27335.1 - 1.9e-07 30.8 0.0 6.5e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM27335.1 - 3e-05 23.2 0.8 0.00019 20.6 0.4 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM27335.1 - 0.019 14.4 0.2 0.18 11.2 0.2 2.2 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Drf_GBD PF06371.13 GAM27335.1 - 0.13 11.8 1.2 0.38 10.3 1.2 1.7 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Aldedh PF00171.22 GAM27336.1 - 3.8e-135 451.0 0.3 4.3e-135 450.8 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SCAMP PF04144.13 GAM27337.1 - 9.3e-15 55.4 19.3 1.3e-14 54.9 19.3 1.1 1 0 0 1 1 1 1 SCAMP family YrzK PF17449.2 GAM27337.1 - 0.12 12.7 0.1 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized YrzK-like DUF2070 PF09843.9 GAM27337.1 - 0.93 7.7 9.4 1.2 7.4 9.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3810 PF12725.7 GAM27337.1 - 3.2 7.0 7.1 1.8 7.8 5.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Presenilin PF01080.17 GAM27337.1 - 5.6 5.6 7.3 0.84 8.3 1.8 2.1 3 0 0 3 3 3 0 Presenilin TPR_1 PF00515.28 GAM27338.1 - 3.3e-10 39.3 0.2 0.0004 20.1 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM27338.1 - 2.2e-08 33.6 0.0 0.0012 18.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAM27338.1 - 1.9e-06 27.6 0.0 0.0026 17.9 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM27338.1 - 3.6e-05 24.0 0.0 0.00024 21.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat PB1 PF00564.24 GAM27338.1 - 0.00017 21.5 0.2 0.00031 20.6 0.2 1.4 1 0 0 1 1 1 1 PB1 domain WW PF00397.26 GAM27338.1 - 0.0003 20.8 0.0 0.00055 20.0 0.0 1.4 1 0 0 1 1 1 1 WW domain TPR_7 PF13176.6 GAM27338.1 - 0.031 14.3 0.0 0.32 11.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM27338.1 - 0.18 11.7 0.0 1.8 8.6 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 GAM27339.1 - 7.5e-50 169.8 55.9 6.9e-36 123.9 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM27339.1 - 1.9e-07 30.3 34.6 6.8e-05 21.9 12.6 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter Ocular_alb PF02101.15 GAM27339.1 - 0.0026 16.8 0.0 0.0072 15.3 0.0 1.7 1 0 0 1 1 1 1 Ocular albinism type 1 protein RabGAP-TBC PF00566.18 GAM27340.1 - 1.6e-23 83.5 7.5 1.1e-20 74.2 5.1 2.4 2 1 0 2 2 2 2 Rab-GTPase-TBC domain AbiJ_NTD4 PF18863.1 GAM27340.1 - 0.0083 16.6 2.0 0.014 15.9 0.2 2.2 2 0 0 2 2 2 1 AbiJ N-terminal domain 4 Med13_C PF06333.12 GAM27340.1 - 0.073 12.3 9.0 0.14 11.4 9.0 1.4 1 1 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF4679 PF15728.5 GAM27340.1 - 0.57 9.2 7.0 0.78 8.7 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) DUF3439 PF11921.8 GAM27340.1 - 0.68 9.9 7.1 1.3 8.9 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF515 PF04415.12 GAM27340.1 - 2.9 6.2 10.1 5 5.4 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) EGF_CA PF07645.15 GAM27341.1 - 7.4e-20 70.9 43.2 2.4e-08 34.0 8.9 7.5 6 1 1 7 7 7 3 Calcium-binding EGF domain cEGF PF12662.7 GAM27341.1 - 4.9e-10 39.2 46.1 2.1e-06 27.5 3.2 6.2 4 1 1 5 5 5 3 Complement Clr-like EGF-like TIG PF01833.24 GAM27341.1 - 2.3e-06 27.6 1.8 2.3e-06 27.6 1.8 5.2 4 2 0 4 4 4 2 IPT/TIG domain EGF_MSP1_1 PF12946.7 GAM27341.1 - 3.7e-05 23.7 2.8 3.7e-05 23.7 2.8 5.7 5 0 0 5 5 5 1 MSP1 EGF domain 1 EGF_3 PF12947.7 GAM27341.1 - 6.6e-05 23.0 19.9 0.0011 19.2 5.3 6.1 5 0 0 5 5 5 3 EGF domain EGF PF00008.27 GAM27341.1 - 0.00015 22.0 67.0 0.0054 17.0 5.4 6.0 5 0 0 5 5 5 4 EGF-like domain Plasmod_Pvs28 PF06247.11 GAM27341.1 - 0.00079 19.7 5.9 0.00079 19.7 5.9 5.9 5 0 0 5 5 5 3 Pvs28 EGF domain FXa_inhibition PF14670.6 GAM27341.1 - 0.0017 18.6 9.3 0.0017 18.6 9.3 6.1 5 1 0 5 5 5 2 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 GAM27341.1 - 0.0018 18.6 14.9 0.0018 18.6 14.9 5.8 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.7 GAM27341.1 - 0.0024 18.5 61.1 0.0042 17.7 5.2 6.6 5 0 0 5 5 5 3 Human growth factor-like EGF DAGAT PF03982.13 GAM27342.1 - 1.5e-105 352.3 0.0 1.9e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Mannosyl_trans PF05007.13 GAM27344.1 - 3.9e-80 269.5 32.0 6.8e-80 268.7 32.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 GAM27344.1 - 6.7e-05 22.1 13.3 6.7e-05 22.1 13.3 3.3 2 1 1 3 3 3 2 GPI transamidase subunit PIG-U GT87 PF09594.10 GAM27344.1 - 0.00033 20.5 0.5 0.00033 20.5 0.5 2.2 1 1 1 2 2 2 1 Glycosyltransferase family 87 HemY_N PF07219.13 GAM27345.1 - 0.013 15.7 0.1 0.013 15.7 0.1 3.4 4 0 0 4 4 4 0 HemY protein N-terminus BAR PF03114.18 GAM27346.1 - 4.9e-16 59.1 7.5 1e-15 58.0 7.5 1.4 1 1 0 1 1 1 1 BAR domain SH3_1 PF00018.28 GAM27346.1 - 9.2e-10 38.0 0.0 1.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM27346.1 - 2e-08 33.7 0.0 3.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAM27346.1 - 2.9e-08 33.4 0.0 5.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.13 GAM27346.1 - 0.02 14.5 3.9 0.62 9.6 3.9 2.4 1 1 0 1 1 1 0 Arfaptin-like domain Elf4 PF07011.11 GAM27346.1 - 0.069 13.1 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Early Flowering 4 domain HIP1_clath_bdg PF16515.5 GAM27346.1 - 0.93 10.1 3.3 2.1 9.0 1.1 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-CCHC PF00098.23 GAM27347.1 - 5.6e-31 105.2 44.3 6.2e-08 32.4 1.2 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 GAM27347.1 - 1.7e-05 24.4 27.1 0.064 13.0 1.1 5.1 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.6 GAM27347.1 - 0.00011 22.1 34.9 0.72 9.9 1.4 5.1 3 2 2 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.6 GAM27347.1 - 0.0013 18.5 1.3 0.0013 18.5 1.3 5.5 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.6 GAM27347.1 - 0.026 14.3 40.6 0.054 13.3 1.3 5.0 4 1 1 5 5 5 0 Zinc knuckle zf-CCHC_5 PF14787.6 GAM27347.1 - 0.8 9.5 34.3 0.61 9.8 2.0 5.1 4 1 1 5 5 5 0 GAG-polyprotein viral zinc-finger ANAPC10 PF03256.16 GAM27348.1 - 1.1e-58 198.0 0.3 1.2e-58 197.8 0.3 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 GAM27348.1 - 7.9e-05 22.8 0.1 0.00011 22.3 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 GAM27348.1 - 0.011 15.9 0.2 0.015 15.5 0.2 1.2 1 0 0 1 1 1 0 PITH domain Sad1_UNC PF07738.13 GAM27348.1 - 0.093 12.7 0.1 0.18 11.8 0.0 1.7 2 1 0 2 2 2 0 Sad1 / UNC-like C-terminal Laminin_N PF00055.17 GAM27348.1 - 0.1 12.2 0.4 0.43 10.1 0.1 1.9 1 1 1 2 2 2 0 Laminin N-terminal (Domain VI) JmjC PF02373.22 GAM27350.1 - 2.2e-37 128.0 1.7 4.9e-37 126.8 0.1 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 GAM27350.1 - 6e-18 65.3 0.1 1.3e-17 64.2 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 GAM27350.1 - 7.3e-18 64.2 3.2 1.5e-17 63.3 3.2 1.6 1 0 0 1 1 1 1 jmjN domain IL4_i_Ig PF18258.1 GAM27350.1 - 0.09 13.0 0.1 0.25 11.6 0.1 1.8 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain Myb_DNA-bind_3 PF12776.7 GAM27350.1 - 0.19 12.8 1.2 0.4 11.7 0.1 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain PIRT PF15099.6 GAM27350.1 - 0.59 9.7 3.4 1.2 8.8 3.4 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family zf-C5HC2 PF02928.16 GAM27351.1 - 7.7e-07 29.4 11.5 1.4e-06 28.6 11.5 1.4 1 0 0 1 1 1 1 C5HC2 zinc finger LIN37 PF15306.6 GAM27351.1 - 0.1 12.8 0.3 0.15 12.3 0.2 1.3 1 1 0 1 1 1 0 LIN37 Dicty_REP PF05086.12 GAM27351.1 - 0.13 10.2 8.6 0.17 9.8 8.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S76 PF13611.6 GAM27351.1 - 0.45 10.8 2.5 1.9 8.8 0.6 2.1 2 0 0 2 2 2 0 Serine peptidase of plant viral polyprotein, P1 DUF5401 PF17380.2 GAM27351.1 - 2.7 6.0 7.0 3.2 5.7 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) FNIP PF05725.12 GAM27353.1 - 1.4e-73 242.8 8.4 1.1e-10 41.4 0.0 10.6 4 4 5 11 11 11 10 FNIP Repeat LRR_8 PF13855.6 GAM27353.1 - 0.0043 16.8 2.0 4.3 7.2 0.0 4.6 3 2 2 5 5 5 2 Leucine rich repeat FNIP PF05725.12 GAM27354.1 - 1.4e-18 66.8 8.1 7.8e-06 26.0 0.3 6.8 3 2 5 8 8 8 5 FNIP Repeat LRR_5 PF13306.6 GAM27354.1 - 0.051 13.6 1.0 0.43 10.5 0.0 2.8 3 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) DUF4518 PF15008.6 GAM27355.1 - 0.0078 15.4 0.3 0.011 14.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) Peptidase_S49_N PF08496.10 GAM27355.1 - 0.016 15.2 1.7 0.016 15.2 1.7 1.7 2 1 0 2 2 2 0 Peptidase family S49 N-terminal DivIC PF04977.15 GAM27355.1 - 0.1 12.3 0.1 0.1 12.3 0.1 3.3 4 0 0 4 4 4 0 Septum formation initiator AI-2E_transport PF01594.16 GAM27355.1 - 0.13 11.4 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 AI-2E family transporter O-antigen_lig PF13425.6 GAM27355.1 - 0.17 10.7 0.4 0.2 10.4 0.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein AAA_lid_1 PF17857.1 GAM27355.1 - 2.5 8.4 6.5 0.17 12.1 1.3 1.7 2 0 0 2 2 2 0 AAA+ lid domain Presenilin PF01080.17 GAM27355.1 - 5.7 5.6 5.1 6.7 5.4 5.1 1.3 1 0 0 1 1 1 0 Presenilin SET PF00856.28 GAM27356.1 - 1.1e-08 35.7 0.1 0.006 17.0 0.0 2.5 1 1 1 2 2 2 2 SET domain Ank_2 PF12796.7 GAM27356.1 - 4.7e-06 27.1 0.0 1.1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM27356.1 - 0.00032 20.9 0.1 0.0082 16.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 GAM27356.1 - 0.00051 20.6 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM27356.1 - 0.00061 20.1 0.1 0.012 16.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 GAM27356.1 - 0.022 15.1 0.1 0.23 11.8 0.0 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) SAF PF08666.12 GAM27356.1 - 0.048 14.3 0.0 9.6 6.9 0.0 2.4 2 0 0 2 2 2 0 SAF domain Med1 PF10744.9 GAM27357.1 - 1.2e-28 100.3 0.1 6.3e-28 98.0 0.1 2.1 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 DASH_Hsk3 PF08227.11 GAM27357.1 - 0.06 13.7 0.4 0.48 10.8 0.1 2.8 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like G-patch PF01585.23 GAM27358.1 - 1.8e-11 43.7 0.1 3.7e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 GAM27358.1 - 2.2e-07 30.8 10.0 2.2e-07 30.8 10.0 1.8 2 0 0 2 2 2 1 OCRE domain G-patch_2 PF12656.7 GAM27358.1 - 3.6e-07 30.2 0.5 9.4e-07 28.8 0.5 1.8 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 GAM27358.1 - 1.6e-05 24.6 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_6 PF13912.6 GAM27358.1 - 0.00077 19.4 0.1 0.0027 17.6 0.1 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAM27358.1 - 0.0015 18.8 0.6 0.0041 17.4 0.6 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 GAM27358.1 - 0.013 16.3 1.4 0.027 15.3 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GAM27358.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-FCS PF06467.14 GAM27358.1 - 0.026 14.4 0.2 0.078 12.9 0.2 1.8 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif PRA-PH PF01503.17 GAM27359.1 - 0.053 14.0 0.2 0.52 10.8 0.1 2.3 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Cupin_8 PF13621.6 GAM27360.1 - 9.2e-10 38.7 4.0 2.9e-09 37.0 1.6 2.8 2 1 0 2 2 2 1 Cupin-like domain IMUP PF15761.5 GAM27360.1 - 4.4 8.0 11.3 9.8 6.9 11.3 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF1117 PF06547.12 GAM27360.1 - 8.1 7.0 7.4 20 5.8 7.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) DUF498 PF04430.14 GAM27361.1 - 3.7e-18 65.6 0.0 6.3e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) EF-hand_7 PF13499.6 GAM27362.1 - 2.4e-18 66.3 10.7 3.1e-05 24.3 2.5 4.0 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 GAM27362.1 - 5.4e-18 63.1 11.8 1.8e-05 23.9 0.1 5.0 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 GAM27362.1 - 1.5e-17 62.0 9.2 0.00033 20.3 0.0 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 GAM27362.1 - 2.6e-13 49.6 14.1 0.0015 18.4 3.8 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 GAM27362.1 - 2.3e-11 42.6 10.1 3.2e-08 32.7 0.0 4.0 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 GAM27362.1 - 0.0001 22.6 1.9 0.51 10.7 0.0 3.2 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAM27362.1 - 0.026 14.5 3.3 0.036 14.0 0.3 2.7 1 1 3 4 4 4 0 Cytoskeletal-regulatory complex EF hand NADPH_Ox PF08414.10 GAM27362.1 - 0.049 14.0 0.4 0.29 11.5 0.1 2.2 2 1 0 2 2 2 0 Respiratory burst NADPH oxidase PCRF PF03462.18 GAM27362.1 - 0.075 12.9 2.5 0.18 11.7 0.7 1.9 2 0 0 2 2 2 0 PCRF domain Cyclin_N PF00134.23 GAM27363.1 - 5.8e-09 35.8 0.6 1.1e-08 34.9 0.6 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3336 PF11815.8 GAM27363.1 - 0.066 12.9 0.4 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) EVE PF01878.18 GAM27363.1 - 0.091 12.8 0.1 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 EVE domain DUF410 PF04190.13 GAM27364.1 - 1.5e-70 237.9 0.0 2e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) VWA PF00092.28 GAM27366.1 - 1.6e-09 38.3 0.0 1.5e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAM27366.1 - 7.8e-08 32.9 0.0 2.3e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain ubiquitin PF00240.23 GAM27366.1 - 1.3e-07 31.2 0.2 3.5e-07 29.9 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin family Ras PF00071.22 GAM27366.1 - 9.6e-07 28.5 1.5 1.4e-05 24.7 0.0 2.9 3 0 0 3 3 3 1 Ras family Roc PF08477.13 GAM27366.1 - 0.013 15.7 0.5 6.8 6.9 0.0 2.8 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad60-SLD PF11976.8 GAM27366.1 - 0.015 15.2 0.1 0.04 13.7 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Orthopox_F8 PF05886.11 GAM27366.1 - 0.026 14.6 0.1 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Orthopoxvirus F8 protein VirE PF05272.11 GAM27366.1 - 0.093 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E FNIP PF05725.12 GAM27367.1 - 6.1e-63 208.8 17.5 4e-12 46.1 0.7 7.3 4 2 3 7 7 7 7 FNIP Repeat LRR_5 PF13306.6 GAM27367.1 - 8.8e-06 25.7 0.8 0.53 10.3 0.2 3.6 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Utp12 PF04003.12 GAM27369.1 - 8.8e-10 38.9 0.5 1.2e-09 38.4 0.5 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family BUD22 PF09073.10 GAM27369.1 - 4.9 6.4 18.0 0.074 12.4 5.8 2.0 1 1 1 2 2 2 0 BUD22 CPP1-like PF11833.8 GAM27370.1 - 0.37 10.4 2.0 1 9.0 2.0 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Tmemb_14 PF03647.13 GAM27370.1 - 0.95 10.2 7.0 1.2 9.9 3.7 2.8 2 0 0 2 2 2 0 Transmembrane proteins 14C Tubulin PF00091.25 GAM27371.1 - 1.7e-68 230.8 0.0 3.2e-68 229.8 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAM27371.1 - 6.3e-43 145.9 0.2 1e-42 145.3 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAM27371.1 - 6.7e-08 32.8 0.0 1.4e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 GAM27371.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 GAM27371.1 - 0.019 14.1 0.0 0.56 9.3 0.0 2.1 2 0 0 2 2 2 0 Tubulin like EGF_2 PF07974.13 GAM27372.1 - 1.2 9.5 6.5 3.1 8.2 6.5 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 GAM27372.1 - 2.3 8.4 5.8 5.4 7.2 5.8 1.6 1 0 0 1 1 1 0 Tenascin EGF domain Kelch_4 PF13418.6 GAM27373.1 - 2.3e-43 145.9 14.6 9.6e-09 35.1 0.4 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM27373.1 - 1e-36 124.5 18.8 2.1e-07 31.0 0.7 7.8 8 1 0 8 8 8 7 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM27373.1 - 4.2e-35 118.9 12.6 2.9e-07 30.6 0.2 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 GAM27373.1 - 3.9e-34 116.1 14.7 3.8e-08 33.2 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 GAM27373.1 - 3.5e-33 112.9 24.5 3.1e-07 29.9 0.4 6.5 7 0 0 7 7 7 6 Kelch motif BTB PF00651.31 GAM27373.1 - 1e-24 86.9 1.4 5.6e-23 81.3 0.3 2.4 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 GAM27373.1 - 3e-20 71.3 10.7 0.00063 19.6 0.1 6.3 6 0 0 6 6 6 5 Kelch motif zf-C2H2_assoc PF16606.5 GAM27373.1 - 0.031 14.5 0.9 0.054 13.7 0.9 1.3 1 0 0 1 1 1 0 Unstructured conserved, between two C2H2-type zinc-fingers NPA PF16469.5 GAM27373.1 - 0.1 13.2 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 DKCLD PF08068.12 GAM27374.1 - 2.7e-34 117.0 0.5 1.6e-32 111.3 0.7 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 GAM27374.1 - 1.8e-22 79.2 0.3 3.2e-22 78.4 0.3 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 GAM27374.1 - 6e-21 74.2 1.1 1.1e-20 73.3 1.1 1.5 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 GAM27374.1 - 2.9e-19 69.9 0.3 2.9e-19 69.9 0.3 4.9 2 2 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 GAM27374.1 - 0.035 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 UPF0113 PUA domain PolyA_pol PF01743.20 GAM27376.1 - 4e-22 79.0 0.2 4e-22 79.0 0.2 2.1 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 GAM27376.1 - 0.0018 18.0 0.0 0.0066 16.2 0.0 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Cyt-b5 PF00173.28 GAM27377.1 - 3.1e-10 40.1 0.0 3.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RTC PF01137.21 GAM27378.1 - 1.3e-80 269.8 0.2 1.6e-80 269.4 0.2 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 GAM27378.1 - 3.9e-18 65.9 0.1 8.8e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CobS_N PF12556.8 GAM27378.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal ANAPC5 PF12862.7 GAM27379.1 - 1.3e-28 98.9 8.8 1.4e-28 98.7 5.9 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 GAM27379.1 - 1.8e-07 31.3 16.4 0.037 14.3 1.3 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAM27379.1 - 6.2e-07 29.1 6.7 0.17 12.2 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM27379.1 - 2.1e-06 27.4 9.2 0.9 9.8 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Glyoxalase_2 PF12681.7 GAM27379.1 - 0.0064 16.4 1.3 0.017 15.1 0.2 2.2 2 0 0 2 2 2 1 Glyoxalase-like domain DUF4477 PF14780.6 GAM27379.1 - 0.027 14.1 0.1 0.16 11.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) TPR_19 PF14559.6 GAM27379.1 - 0.027 15.0 4.3 2.7 8.6 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM27379.1 - 0.058 13.2 7.0 2.7 8.0 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM27379.1 - 0.12 13.1 2.6 6.6 7.6 0.0 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM27379.1 - 0.16 11.9 2.0 18 5.4 0.0 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM27379.1 - 0.24 12.1 0.8 2.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM27379.1 - 1.4 9.2 13.8 1.6 9.0 1.7 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TatD_DNase PF01026.21 GAM27380.1 - 1.1e-57 195.4 0.1 2.1e-57 194.4 0.0 1.5 2 0 0 2 2 2 1 TatD related DNase Gemini_AL1_M PF08283.11 GAM27380.1 - 0.014 15.4 0.1 0.039 14.0 0.0 1.7 2 0 0 2 2 2 0 Geminivirus rep protein central domain Amidohydro_2 PF04909.14 GAM27380.1 - 0.021 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase SR-25 PF10500.9 GAM27380.1 - 0.027 14.1 2.3 0.04 13.5 2.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_L1 PF00687.21 GAM27381.1 - 3.6e-43 147.7 3.9 4.2e-43 147.5 3.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Fib_alpha PF08702.10 GAM27381.1 - 0.91 9.7 5.0 5.9 7.1 0.6 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 GAM27383.1 - 1.4e-23 83.6 1.0 6.4e-23 81.4 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain WD40 PF00400.32 GAM27383.1 - 1.3e-12 48.0 13.4 1.7e-05 25.4 0.1 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 GAM27383.1 - 3.8e-10 39.5 0.0 9.5e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 GAM27383.1 - 1.3e-05 25.0 0.2 0.19 12.1 0.1 4.1 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 GAM27383.1 - 0.0046 17.3 0.0 3.4 8.1 0.0 3.3 2 1 2 4 4 4 1 HEAT repeats APH PF01636.23 GAM27383.1 - 0.013 15.5 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Coiled PF05710.12 GAM27384.1 - 1.3e-09 38.7 28.0 2.3e-08 34.7 28.0 2.0 1 1 0 1 1 1 1 Coiled coil PrmA PF06325.13 GAM27385.1 - 2.3e-09 37.1 0.1 3e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAM27385.1 - 1.4e-08 35.4 0.0 3.1e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM27385.1 - 4e-08 33.3 0.0 6.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM27385.1 - 9.2e-08 32.7 0.2 9.9e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM27385.1 - 2.9e-06 27.8 0.1 9.3e-06 26.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Met_10 PF02475.16 GAM27385.1 - 4.4e-06 26.6 0.1 6.1e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 GAM27385.1 - 8.8e-06 25.6 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 GAM27385.1 - 9.6e-06 25.5 0.3 1.7e-05 24.8 0.0 1.5 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase MTS PF05175.14 GAM27385.1 - 0.00015 21.4 0.1 0.00024 20.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 GAM27385.1 - 0.012 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 GAM27385.1 - 0.042 13.6 0.1 0.065 13.0 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 GAM27385.1 - 0.06 13.0 0.0 0.088 12.4 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 GidB PF02527.15 GAM27385.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RasGEF PF00617.19 GAM27386.1 - 1e-51 175.7 2.9 2e-51 174.7 2.9 1.4 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.29 GAM27386.1 - 5.4e-18 64.9 0.2 6.4e-09 35.8 0.0 3.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RasGEF_N PF00618.20 GAM27386.1 - 2.5e-15 56.6 0.9 9.2e-15 54.8 0.9 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif GRAM PF02893.20 GAM27386.1 - 1.5e-12 47.4 0.2 9.4e-12 44.8 0.1 2.4 2 0 0 2 2 2 1 GRAM domain Vps36_ESCRT-II PF11605.8 GAM27386.1 - 0.031 14.5 0.7 0.48 10.6 0.1 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Coq4 PF05019.13 GAM27389.1 - 1.3e-88 296.0 0.0 1.9e-88 295.5 0.0 1.2 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 E1_DerP2_DerF2 PF02221.15 GAM27390.1 - 8.7e-22 78.0 0.2 1.1e-21 77.7 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 GAM27390.1 - 4.6e-06 27.0 0.5 8.2e-06 26.2 0.5 1.3 1 0 0 1 1 1 1 ML-like domain BPL_LplA_LipB PF03099.19 GAM27391.1 - 3.2e-18 65.9 0.0 5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 GAM27391.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain BPL_LplA_LipB_2 PF16917.5 GAM27391.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family RhoGEF PF00621.20 GAM27392.1 - 2.6e-27 96.3 0.0 7.3e-27 94.8 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain IQ_SEC7_PH PF16453.5 GAM27392.1 - 0.0023 17.9 0.2 0.0077 16.2 0.0 1.9 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.17 GAM27392.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DnaJ PF00226.31 GAM27393.1 - 4.5e-06 26.7 0.2 1.2e-05 25.4 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain SUIM_assoc PF16619.5 GAM27393.1 - 9e-06 25.7 4.1 2.4e-05 24.3 4.1 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 BUD22 PF09073.10 GAM27393.1 - 0.00069 19.1 3.3 0.00082 18.8 3.3 1.2 1 0 0 1 1 1 1 BUD22 Myc_N PF01056.18 GAM27393.1 - 0.0012 18.8 3.0 0.0016 18.4 3.0 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Spt20 PF12090.8 GAM27393.1 - 0.0054 16.4 13.3 0.0054 16.4 13.3 1.7 2 0 0 2 2 2 1 Spt20 family CENP-B_dimeris PF09026.10 GAM27393.1 - 0.013 15.8 9.2 0.013 15.8 9.2 1.9 2 0 0 2 2 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 GAM27393.1 - 0.016 14.9 14.8 0.028 14.2 14.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ASD2 PF08687.11 GAM27393.1 - 0.05 13.2 3.8 0.09 12.3 3.8 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Spc7_N PF15402.6 GAM27393.1 - 0.063 11.5 10.8 0.078 11.2 10.8 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DNA_pol_phi PF04931.13 GAM27393.1 - 0.066 11.3 6.6 0.11 10.6 6.6 1.4 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 GAM27393.1 - 0.07 12.1 2.4 0.099 11.6 2.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Androgen_recep PF02166.16 GAM27393.1 - 0.078 11.8 9.4 0.1 11.4 9.4 1.1 1 0 0 1 1 1 0 Androgen receptor CCDC53 PF10152.9 GAM27393.1 - 0.13 12.7 5.7 0.2 12.0 5.7 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4834 PF16118.5 GAM27393.1 - 0.2 12.6 2.6 0.45 11.5 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ndc1_Nup PF09531.10 GAM27393.1 - 0.84 8.2 4.3 1.1 7.8 4.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 GAM27393.1 - 0.9 8.7 2.0 1 8.5 2.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Paramyxo_ncap PF00973.19 GAM27393.1 - 1.3 7.8 4.1 1.9 7.3 4.1 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NOA36 PF06524.12 GAM27393.1 - 1.9 7.8 14.3 2.8 7.2 14.3 1.2 1 0 0 1 1 1 0 NOA36 protein CNDH2_M PF16869.5 GAM27393.1 - 2.2 9.0 16.5 4.2 8.0 16.5 1.4 1 0 0 1 1 1 0 PF16858 UPF0524 PF15823.5 GAM27393.1 - 2.8 7.3 7.7 4.4 6.6 7.7 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 DivIC PF04977.15 GAM27393.1 - 6.1 6.7 9.4 15 5.5 9.4 1.6 1 0 0 1 1 1 0 Septum formation initiator Presenilin PF01080.17 GAM27393.1 - 8.3 5.1 8.7 11 4.7 8.7 1.1 1 0 0 1 1 1 0 Presenilin Cwf_Cwc_15 PF04889.12 GAM27396.1 - 8.1e-49 166.6 44.9 1.3e-48 166.0 44.9 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 GAM27396.1 - 0.0026 17.2 41.1 0.003 17.0 41.1 1.1 1 0 0 1 1 1 1 BUD22 Macoilin PF09726.9 GAM27396.1 - 0.28 9.7 22.5 0.37 9.3 22.5 1.2 1 0 0 1 1 1 0 Macoilin family CAC1F_C PF16885.5 GAM27396.1 - 0.88 9.2 21.1 1.2 8.7 21.1 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Tir_receptor_C PF07489.11 GAM27396.1 - 0.89 9.5 10.7 2.1 8.3 10.7 1.8 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Nop14 PF04147.12 GAM27396.1 - 4.6 5.3 44.1 5.9 5.0 44.1 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2981 PF11200.8 GAM27396.1 - 5.1 6.7 12.0 6.2 6.5 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) FNIP PF05725.12 GAM27397.1 - 6.3e-55 183.1 7.8 1.4e-13 50.8 0.0 7.6 7 1 0 8 8 8 7 FNIP Repeat Complex1_LYR PF05347.15 GAM27398.1 - 0.11 12.5 0.7 0.19 11.8 0.7 1.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Beta-Casp PF10996.8 GAM27399.1 - 1.3e-21 77.0 0.0 2.8e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 GAM27399.1 - 4.8e-18 64.8 0.0 1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 GAM27399.1 - 1.3e-11 44.3 0.0 6.9e-11 41.9 0.0 2.1 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 GAM27399.1 - 0.005 16.1 0.0 0.28 10.4 0.0 2.6 1 1 1 2 2 2 1 Putative beta-lactamase-like family Lactamase_B PF00753.27 GAM27399.1 - 0.04 13.9 0.1 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily RANK_CRD_2 PF18278.1 GAM27399.1 - 0.05 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 DMAP1 PF05499.12 GAM27400.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) TSC22 PF01166.18 GAM27401.1 - 0.042 14.2 0.6 0.074 13.4 0.6 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family SNARE_assoc PF09335.11 GAM27402.1 - 5.4e-18 65.6 9.9 1e-17 64.7 9.9 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein TILa PF12714.7 GAM27403.1 - 0.0041 17.1 95.7 0.34 10.9 2.1 12.1 8 2 4 12 12 12 7 TILa domain FOLN PF09289.10 GAM27403.1 - 0.025 14.8 0.9 0.025 14.8 0.9 10.2 11 0 0 11 11 11 0 Follistatin/Osteonectin-like EGF domain STATa_Ig PF18214.1 GAM27404.1 - 3.8e-06 26.9 3.1 0.029 14.4 1.4 2.8 2 1 0 2 2 2 1 STATa Immunoglobulin-like domain SR-25 PF10500.9 GAM27404.1 - 0.01 15.4 5.8 0.017 14.8 5.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TMEM154 PF15102.6 GAM27404.1 - 9.9 6.1 9.0 22 4.9 9.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF423 PF04241.15 GAM27405.1 - 2.4e-27 95.0 0.8 3.2e-27 94.5 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Rubis-subs-bind PF09273.11 GAM27406.1 - 9e-19 68.4 0.0 1.7e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 GAM27406.1 - 4.5e-10 40.2 0.2 3.4e-09 37.3 0.0 2.5 3 1 0 3 3 3 1 SET domain Ribosomal_L19e PF01280.20 GAM27407.1 - 9e-13 48.5 0.0 1.1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e RhoGEF PF00621.20 GAM27408.1 - 8.8e-50 169.5 1.0 1.5e-49 168.7 1.0 1.4 1 0 0 1 1 1 1 RhoGEF domain CH PF00307.31 GAM27408.1 - 9.9e-23 80.4 0.5 4e-20 72.0 0.1 2.9 2 0 0 2 2 2 2 Calponin homology (CH) domain CDC24 PF06395.11 GAM27408.1 - 0.00016 21.9 0.1 0.00054 20.2 0.0 1.9 2 0 0 2 2 2 1 CDC24 Calponin IQ PF00612.27 GAM27408.1 - 0.018 14.8 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif PH_13 PF16652.5 GAM27408.1 - 0.033 14.0 0.1 0.29 10.9 0.1 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain Med2 PF11214.8 GAM27408.1 - 0.034 14.3 0.2 0.14 12.4 0.2 2.0 1 0 0 1 1 1 0 Mediator complex subunit 2 HTH_45 PF14947.6 GAM27408.1 - 0.056 13.4 0.5 0.25 11.4 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix Myb_DNA-binding PF00249.31 GAM27409.1 - 3e-24 84.9 8.3 1.5e-11 44.3 0.5 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM27409.1 - 1.5e-20 73.2 6.7 1.6e-14 53.9 0.9 3.4 3 1 1 4 4 4 2 Myb-like DNA-binding domain PHD PF00628.29 GAM27409.1 - 0.0035 17.2 8.6 0.012 15.5 8.6 2.0 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 GAM27409.1 - 0.01 15.8 4.1 0.027 14.4 4.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 GAM27409.1 - 0.25 10.9 7.2 0.65 9.6 7.2 1.8 1 0 0 1 1 1 0 PHD-finger FYVE_2 PF02318.16 GAM27409.1 - 3.2 8.0 12.7 0.021 15.0 3.6 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Sulfate_transp PF00916.20 GAM27411.1 - 1.1e-95 320.7 24.7 1.1e-95 320.7 24.7 1.5 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 GAM27411.1 - 1.4e-17 63.4 0.1 2.4e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAM27411.1 - 0.0031 17.9 5.0 0.0031 17.9 5.0 3.2 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 GAM27411.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 STAS domain GATase PF00117.28 GAM27413.1 - 1.6e-09 37.8 0.2 1.2e-08 34.9 0.2 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 GAM27413.1 - 0.0072 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 GAM27413.1 - 0.0082 15.9 0.1 0.043 13.6 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 UQ_con PF00179.26 GAM27414.1 - 1.2e-47 161.1 0.0 1.3e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM27414.1 - 0.002 17.8 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GAM27414.1 - 0.039 13.8 0.0 0.078 12.8 0.0 1.5 1 1 0 1 1 1 0 UEV domain SapB_1 PF05184.15 GAM27415.1 - 2.7e-13 49.6 5.5 1.2e-07 31.6 0.2 3.3 2 1 0 2 2 2 2 Saposin-like type B, region 1 SapB_2 PF03489.17 GAM27415.1 - 0.0085 16.2 0.2 0.0085 16.2 0.2 4.1 5 0 0 5 5 5 1 Saposin-like type B, region 2 Dynactin_p62 PF05502.13 GAM27415.1 - 3.7 6.2 7.8 0.37 9.5 0.5 2.4 3 0 0 3 3 3 0 Dynactin p62 family TRAPP PF04051.16 GAM27416.1 - 5.4e-34 117.0 0.2 7.1e-34 116.6 0.2 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Cellulose_synt PF03552.14 GAM27417.1 - 0.067 11.7 1.1 0.11 11.0 1.1 1.3 1 0 0 1 1 1 0 Cellulose synthase Nop14 PF04147.12 GAM27417.1 - 0.58 8.3 27.4 0.8 7.8 27.4 1.2 1 0 0 1 1 1 0 Nop14-like family Glypican PF01153.19 GAM27417.1 - 0.93 8.3 7.1 1.4 7.7 7.1 1.3 1 0 0 1 1 1 0 Glypican Zip PF02535.22 GAM27417.1 - 5.3 6.1 5.6 7 5.8 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ank PF00023.30 GAM27418.1 - 5.8e-06 26.5 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 GAM27418.1 - 0.0028 18.2 0.0 0.013 16.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM27418.1 - 0.03 14.9 0.0 0.2 12.3 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM27418.1 - 0.088 13.2 0.0 0.83 10.1 0.0 2.3 1 1 0 1 1 1 0 Ankyrin repeats (many copies) IGR PF09597.10 GAM27419.1 - 5.6e-24 84.0 0.3 9e-24 83.3 0.3 1.3 1 0 0 1 1 1 1 IGR protein motif FBA_2 PF07735.17 GAM27419.1 - 0.17 12.0 0.2 0.17 12.0 0.2 2.1 2 0 0 2 2 2 0 F-box associated Methyltransf_7 PF03492.15 GAM27420.1 - 1.5e-44 152.6 0.3 1.9e-44 152.3 0.3 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Endopep_inhib PF16800.5 GAM27420.1 - 0.035 14.0 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 IseA DL-endopeptidase inhibitor RabGAP-TBC PF00566.18 GAM27421.1 - 5.9e-26 91.5 0.7 5.9e-26 91.5 0.7 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Coilin_N PF15862.5 GAM27421.1 - 0.095 12.5 0.3 0.095 12.5 0.3 2.7 3 0 0 3 3 3 0 Coilin N-terminus zf-C2HE PF16278.5 GAM27421.1 - 0.16 12.5 1.8 0.6 10.6 0.1 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF737 PF05300.11 GAM27421.1 - 0.69 10.2 12.3 1.2 9.5 12.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF737) DUF962 PF06127.11 GAM27422.1 - 5e-21 74.6 11.3 3.5e-20 71.9 11.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Alpha_L_fucos PF01120.17 GAM27423.1 - 1.9e-113 379.5 6.6 2.3e-113 379.2 6.6 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 GAM27423.1 - 4.9e-14 52.7 0.0 9.5e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain NAD_binding_6 PF08030.12 GAM27424.1 - 1.2e-32 113.2 0.0 1.9e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAM27424.1 - 9.1e-21 74.3 10.5 2.3e-20 73.0 10.5 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAM27424.1 - 1.6e-17 63.6 0.0 4.3e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 GAM27424.1 - 0.00091 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAM27424.1 - 0.092 13.4 0.0 0.46 11.1 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain zf-C2H2_4 PF13894.6 GAM27425.1 - 0.0055 17.5 1.1 0.0055 17.5 1.1 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAM27425.1 - 0.0092 16.3 0.7 0.0092 16.3 0.7 2.5 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) ARS2 PF04959.13 GAM27425.1 - 0.01 16.2 0.2 0.021 15.2 0.1 1.5 1 1 0 1 1 1 0 Arsenite-resistance protein 2 zf-C2H2_jaz PF12171.8 GAM27425.1 - 0.02 15.2 1.2 0.02 15.2 1.2 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Baculo_11_kDa PF06143.11 GAM27425.1 - 0.022 14.3 1.4 0.34 10.5 0.2 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family zf-C2H2 PF00096.26 GAM27425.1 - 0.081 13.4 1.0 0.081 13.4 1.0 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type RDD PF06271.12 GAM27425.1 - 0.1 12.8 0.1 0.25 11.5 0.0 1.6 2 0 0 2 2 2 0 RDD family zf-met PF12874.7 GAM27425.1 - 0.89 10.0 5.9 0.85 10.1 0.6 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ribosomal_L7Ae PF01248.26 GAM27426.1 - 4.2e-22 77.7 4.4 1.5e-21 75.9 4.4 1.8 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF496 PF04363.12 GAM27426.1 - 0.015 15.3 0.5 0.022 14.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF496) ATPase_2 PF01637.18 GAM27426.1 - 0.12 12.3 1.4 0.17 11.8 1.1 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PXPV PF12778.7 GAM27427.1 - 0.043 13.7 18.2 0.043 13.7 18.2 3.4 1 1 3 4 4 4 0 PXPV repeat (3 copies) Pkinase PF00069.25 GAM27428.1 - 4.2e-55 186.9 0.1 1.9e-53 181.6 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27428.1 - 1.4e-23 83.5 0.3 2e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAM27428.1 - 0.00011 21.6 0.1 0.54 9.5 0.0 3.2 3 0 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 GAM27428.1 - 0.00076 18.5 1.0 0.00076 18.5 1.0 2.1 3 0 0 3 3 3 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM27428.1 - 0.046 12.5 0.0 0.1 11.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Drf_DAD PF06345.11 GAM27428.1 - 0.12 12.5 0.3 0.42 10.7 0.3 1.9 1 0 0 1 1 1 0 DRF Autoregulatory Domain Kdo PF06293.14 GAM27428.1 - 0.13 11.6 0.1 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAM27428.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 GAM27428.1 - 0.21 11.5 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1117 PF06547.12 GAM27428.1 - 6.2 7.4 6.3 6.5 7.3 2.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) SdrD_B PF17210.3 GAM27430.1 - 5.2e-22 78.2 4.9 2.9e-09 37.1 0.1 3.6 2 1 0 3 3 3 3 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM27430.1 - 8.9e-15 54.7 0.6 0.00033 20.9 0.0 3.6 3 0 0 3 3 3 3 Carboxypeptidase regulatory-like domain CBS PF00571.28 GAM27430.1 - 7.4e-13 48.7 0.7 2.6e-07 31.0 0.1 3.5 3 0 0 3 3 3 2 CBS domain SpaA PF17802.1 GAM27430.1 - 2.6e-09 37.3 4.8 0.075 13.4 0.2 3.6 3 0 0 3 3 3 3 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 GAM27430.1 - 0.00066 19.6 1.0 6.7 6.8 0.0 3.9 3 0 0 3 3 3 2 CarboxypepD_reg-like domain Y_Y_Y PF07495.13 GAM27430.1 - 0.00098 19.0 0.2 4.5 7.3 0.0 3.5 3 0 0 3 3 3 1 Y_Y_Y domain FlgD_ig PF13860.6 GAM27430.1 - 0.0024 17.7 1.3 5.7 6.9 0.0 4.6 5 0 0 5 5 5 1 FlgD Ig-like domain DUF2141 PF09912.9 GAM27430.1 - 0.0042 17.0 0.0 26 4.8 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2141) fn3_3 PF14686.6 GAM27430.1 - 0.019 14.7 0.6 15 5.4 0.0 3.6 3 0 0 3 3 3 0 Polysaccharide lyase family 4, domain II ApeC PF16977.5 GAM27430.1 - 0.13 12.2 1.1 34 4.3 0.0 3.2 2 1 0 3 3 3 0 C-terminal domain of apextrin PPC PF04151.15 GAM27430.1 - 0.17 13.0 7.6 7.1 7.8 0.1 4.9 5 0 0 5 5 5 0 Bacterial pre-peptidase C-terminal domain Tyrosinase PF00264.20 GAM27431.1 - 2.5e-37 129.3 0.9 4.4e-37 128.5 0.9 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Aldo_ket_red PF00248.21 GAM27432.1 - 3.8e-47 160.9 0.1 1.3e-45 155.9 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 GAM27433.1 - 2.2e-46 154.9 12.2 8.1e-09 36.0 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM27433.1 - 6e-12 45.7 0.2 0.0065 16.7 0.0 5.1 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM27433.1 - 8.2e-09 34.9 0.1 0.024 13.6 0.0 4.5 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAM27433.1 - 3.4e-07 29.3 0.2 0.36 9.4 0.1 4.9 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAM27433.1 - 0.00081 18.3 0.2 1.2 7.8 0.0 4.1 1 1 4 5 5 5 1 Nup133 N terminal like PALB2_WD40 PF16756.5 GAM27433.1 - 0.0017 17.4 1.7 0.0035 16.3 0.1 2.2 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 GAM27433.1 - 0.011 14.3 0.0 3.1 6.2 0.0 2.8 2 1 0 2 2 2 0 Cytochrome D1 heme domain Cytochrom_C1 PF02167.15 GAM27434.1 - 2.5e-90 302.0 0.0 3e-90 301.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 GAM27434.1 - 0.00062 20.0 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 GAM27434.1 - 0.035 15.2 0.5 0.11 13.6 0.4 1.8 1 1 0 1 1 1 0 Cytochrome c Cpn60_TCP1 PF00118.24 GAM27435.1 - 2e-105 353.3 6.7 2.3e-105 353.1 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3430 PF11912.8 GAM27437.1 - 8.4e-14 52.1 19.5 9.5e-14 51.9 19.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) bZIP_C PF12498.8 GAM27437.1 - 0.45 11.5 1.6 0.86 10.6 0.4 1.9 1 1 1 2 2 2 0 Basic leucine-zipper C terminal Rap_GAP PF02145.15 GAM27438.1 - 4.4e-62 208.9 0.1 1.1e-61 207.6 0.1 1.7 1 0 0 1 1 1 1 Rap/ran-GAP G-alpha PF00503.20 GAM27439.1 - 5.7e-99 331.6 7.5 7.1e-99 331.3 7.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAM27439.1 - 4.5e-15 55.5 1.4 2.6e-10 40.0 0.2 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM27439.1 - 4.5e-05 22.9 1.1 0.0065 15.9 0.2 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM27439.1 - 0.0032 17.0 3.3 0.024 14.2 0.2 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 GAM27439.1 - 0.021 15.0 0.7 2.9 8.1 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SR-25 PF10500.9 GAM27439.1 - 0.082 12.5 2.4 0.13 11.9 2.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_29 PF13555.6 GAM27439.1 - 0.1 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PGG PF13962.6 GAM27440.1 - 0.064 13.1 0.4 0.064 13.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function 7tm_2 PF00002.24 GAM27440.1 - 0.13 11.6 15.5 0.24 10.6 15.5 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Coiled PF05710.12 GAM27441.1 - 3.9e-08 34.0 5.4 4.4e-08 33.8 5.4 1.1 1 0 0 1 1 1 1 Coiled coil PAT1 PF09770.9 GAM27442.1 - 1.8e-07 29.9 0.7 1.8e-07 29.9 0.7 4.2 1 1 2 3 3 3 2 Topoisomerase II-associated protein PAT1 Chromo PF00385.24 GAM27443.1 - 1.4e-13 50.6 4.5 2.8e-13 49.6 4.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 GAM27443.1 - 0.042 14.0 0.3 0.074 13.2 0.3 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 PBP1_TM PF14812.6 GAM27443.1 - 0.15 12.4 31.0 1.1 9.7 5.6 4.8 4 1 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AT_hook PF02178.19 GAM27443.1 - 0.75 9.9 54.0 0.36 10.8 4.4 5.9 6 0 0 6 6 6 0 AT hook motif Myc_N PF01056.18 GAM27443.1 - 6.7 6.5 50.8 0.91 9.4 6.8 3.6 1 1 1 3 3 3 0 Myc amino-terminal region Pkinase PF00069.25 GAM27444.1 - 4.1e-69 232.9 0.0 4.1e-69 232.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27444.1 - 5.5e-50 170.1 0.0 1.3e-49 168.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAM27444.1 - 5.1e-15 55.6 2.3 8.5e-15 54.9 0.2 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 GAM27444.1 - 2.7e-06 26.4 0.0 2.7e-06 26.4 0.0 3.5 4 0 0 4 4 4 1 Fungal protein kinase GTP_EFTU PF00009.27 GAM27445.1 - 3e-62 209.6 0.1 4.6e-62 209.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAM27445.1 - 1.7e-34 118.2 0.0 4e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 GAM27445.1 - 1.7e-32 111.3 0.0 9.5e-32 108.9 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 GAM27445.1 - 6.4e-25 87.0 0.1 1.4e-24 85.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAM27445.1 - 4e-11 43.1 0.1 1.1e-10 41.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAM27445.1 - 1.3e-06 28.2 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 GAM27445.1 - 0.00054 20.0 0.1 0.0013 18.8 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AglB_L1 PF18079.1 GAM27445.1 - 0.016 15.4 1.0 0.65 10.3 0.0 3.0 3 0 0 3 3 3 0 Archaeal glycosylation protein B long peripheral domain DUF442 PF04273.13 GAM27445.1 - 0.018 15.1 0.0 23 5.1 0.0 3.3 3 0 0 3 3 3 0 Putative phosphatase (DUF442) AvrPtoB_bdg PF16847.5 GAM27445.1 - 0.07 13.6 0.1 1.3 9.5 0.0 2.9 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain FeoB_N PF02421.18 GAM27445.1 - 0.082 12.4 0.2 1.3 8.5 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 GAM27445.1 - 0.088 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 AIG1 family SUI1 PF01253.22 GAM27445.1 - 0.1 13.1 0.0 0.35 11.4 0.0 1.9 1 0 0 1 1 1 0 Translation initiation factor SUI1 Peptidase_M66 PF10462.9 GAM27447.1 - 2.3e-74 250.1 0.9 3e-74 249.7 0.9 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 GAM27447.1 - 0.00074 20.0 0.2 0.0027 18.2 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like BppL_N PF18338.1 GAM27447.1 - 0.0013 18.4 0.6 0.0013 18.4 0.6 2.0 2 0 0 2 2 2 1 Lower baseplate protein N-terminal domain Peptidase_M10 PF00413.24 GAM27447.1 - 0.033 14.0 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Matrixin Metallopep PF12044.8 GAM27447.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Astacin PF01400.24 GAM27447.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF3827 PF12877.7 GAM27447.1 - 0.43 8.9 1.1 0.55 8.5 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Peptidase_M66 PF10462.9 GAM27448.1 - 2.5e-76 256.5 1.9 3.2e-76 256.2 1.9 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 GAM27448.1 - 0.023 15.2 0.1 0.047 14.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SPC25 PF06703.11 GAM27448.1 - 0.073 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Peptidase_M66 PF10462.9 GAM27449.1 - 3.7e-78 262.6 0.8 5.2e-78 262.1 0.8 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 GAM27449.1 - 0.024 15.1 0.7 0.1 13.2 0.7 2.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 GAM27449.1 - 0.036 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Matrixin Sigma_reg_N PF13800.6 GAM27449.1 - 0.071 13.4 1.2 0.14 12.4 1.2 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Shisa PF13908.6 GAM27449.1 - 0.097 12.9 7.9 0.18 12.1 7.9 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Mucin PF01456.17 GAM27449.1 - 0.29 11.1 32.2 0.7 9.9 32.2 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein SpoIIIAH PF12685.7 GAM27449.1 - 0.85 9.4 4.2 1.2 8.9 4.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein SOG2 PF10428.9 GAM27449.1 - 6.4 5.9 13.2 8.9 5.4 13.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_M66 PF10462.9 GAM27450.1 - 2.1e-74 250.2 3.7 2.6e-74 249.9 3.7 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 GAM27450.1 - 0.0016 18.9 0.3 0.0037 17.8 0.3 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 GAM27450.1 - 0.064 11.8 0.3 0.11 11.1 0.3 1.3 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M10 PF00413.24 GAM27450.1 - 0.093 12.6 0.8 0.17 11.7 0.8 1.5 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 GAM27451.1 - 1.5e-73 247.5 3.4 2e-73 247.1 3.4 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 GAM27451.1 - 0.0056 17.2 0.1 0.016 15.7 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 GAM27452.1 - 1.2e-71 241.2 3.9 1.5e-71 240.9 3.9 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 GAM27452.1 - 0.018 15.5 0.1 0.046 14.2 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like HEAT_2 PF13646.6 GAM27453.1 - 3.3e-16 59.4 0.0 2.7e-05 24.5 0.0 4.7 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 GAM27453.1 - 6.1e-15 54.1 1.0 0.0095 16.1 0.0 7.4 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 GAM27453.1 - 4.5e-06 26.8 17.3 0.019 15.0 0.1 4.8 4 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 GAM27453.1 - 2.5e-05 24.4 2.1 0.092 12.9 0.0 4.4 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 GAM27453.1 - 4e-05 24.0 0.0 0.35 11.4 0.0 3.7 4 0 0 4 4 4 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAM27453.1 - 0.002 18.7 2.5 9.6 6.9 0.1 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 GAM27453.1 - 0.0035 16.6 2.1 0.77 8.9 0.1 2.9 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain DUF4042 PF13251.6 GAM27453.1 - 0.041 13.6 0.8 0.39 10.4 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) Cohesin_HEAT PF12765.7 GAM27453.1 - 0.045 14.0 1.4 9.7 6.6 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion SUIM_assoc PF16619.5 GAM27453.1 - 3.3 7.9 10.6 0.021 14.8 1.5 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cpn60_TCP1 PF00118.24 GAM27454.1 - 5.3e-70 236.4 6.0 6.5e-70 236.1 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L24e PF01246.20 GAM27455.1 - 2.2e-25 88.7 0.3 6e-25 87.3 0.3 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e DUF775 PF05603.12 GAM27455.1 - 0.026 14.1 1.3 0.032 13.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ribosomal_S8e PF01201.22 GAM27456.1 - 4.6e-48 162.9 2.9 6.4e-48 162.4 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e HSP90 PF00183.18 GAM27457.1 - 1.2e-175 585.4 14.5 1.6e-175 584.9 14.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GAM27457.1 - 3.9e-12 46.7 0.2 9.1e-12 45.5 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAM27457.1 - 1.8e-09 37.6 0.2 6e-09 35.8 0.2 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2500 PF10694.9 GAM27457.1 - 0.0045 17.5 0.9 0.017 15.6 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2500) HK_sensor PF16750.5 GAM27457.1 - 0.038 14.3 0.1 9.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Sensor domain of 2-component histidine kinase SPOC PF07744.13 GAM27457.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 SPOC domain Methyltransf_10 PF05971.12 GAM27457.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA methyltransferase Erf4 PF10256.9 GAM27458.1 - 3e-24 85.4 0.3 3.7e-24 85.1 0.3 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF1084 PF06454.11 GAM27459.1 - 5.5e-10 39.1 10.1 6.7e-10 38.8 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Ninjurin PF04923.12 GAM27459.1 - 0.12 12.4 3.2 0.25 11.3 3.2 1.6 1 0 0 1 1 1 0 Ninjurin AC_N PF16214.5 GAM27459.1 - 0.69 9.0 2.2 0.87 8.6 2.2 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region adh_short PF00106.25 GAM27460.1 - 1.1e-57 194.7 0.7 1.5e-57 194.2 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM27460.1 - 1.3e-39 136.2 0.1 1.5e-39 136.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM27460.1 - 7.8e-18 65.0 0.1 1.1e-17 64.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM27460.1 - 0.0003 20.0 1.1 0.0005 19.3 1.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAM27460.1 - 0.002 17.6 0.1 0.0028 17.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM27460.1 - 0.0096 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAM27460.1 - 0.014 15.7 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAM27460.1 - 0.014 15.4 0.5 0.046 13.8 0.5 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 GAM27460.1 - 0.015 14.7 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PTA_PTB PF01515.19 GAM27460.1 - 0.024 14.0 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase ApbA PF02558.16 GAM27460.1 - 0.052 13.2 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Coiled PF05710.12 GAM27461.1 - 1.3e-07 32.4 15.7 1.5e-07 32.2 15.7 1.1 1 0 0 1 1 1 1 Coiled coil RabGAP-TBC PF00566.18 GAM27462.1 - 7e-57 192.5 3.9 7e-57 192.5 3.9 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain HTH_52 PF18576.1 GAM27462.1 - 0.091 13.0 0.5 0.091 13.0 0.5 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain Mob_Pre PF01076.19 GAM27462.1 - 1.4 8.7 7.8 0.61 9.9 5.3 1.6 2 0 0 2 2 2 0 Plasmid recombination enzyme Gelsolin PF00626.22 GAM27463.1 - 1.3e-64 214.1 13.6 5.1e-14 51.9 0.0 8.3 8 0 0 8 8 8 7 Gelsolin repeat LRR_8 PF13855.6 GAM27463.1 - 1.9e-26 91.6 37.5 2.5e-10 39.9 5.0 4.9 3 1 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 GAM27463.1 - 1.6e-15 56.9 44.9 0.00018 21.8 3.8 5.9 3 1 2 6 6 6 6 Leucine Rich repeats (2 copies) VHP PF02209.19 GAM27463.1 - 9e-13 48.1 5.1 9e-13 48.1 5.1 2.2 2 0 0 2 2 2 1 Villin headpiece domain LRR_1 PF00560.33 GAM27463.1 - 3.7 8.5 30.1 34 5.5 0.0 9.2 9 1 0 9 9 9 0 Leucine Rich Repeat SdrD_B PF17210.3 GAM27464.1 - 7.6e-59 196.8 37.2 8.9e-10 38.8 0.6 7.2 7 0 0 7 7 7 7 SdrD B-like domain DUF3244 PF11589.8 GAM27464.1 - 9.1e-09 35.3 0.0 11 6.2 0.0 6.5 7 0 0 7 7 7 3 Domain of unknown function (DUF3244) DUF2012 PF09430.10 GAM27464.1 - 8.7e-06 25.9 0.0 1.1 9.4 0.0 6.1 7 0 0 7 7 7 1 Protein of unknown function (DUF2012) ImmE5 PF11480.8 GAM27464.1 - 0.00026 21.4 0.1 30 5.2 0.0 5.1 5 0 0 5 5 5 0 Colicin-E5 Imm protein bMG6 PF17962.1 GAM27464.1 - 0.11 12.7 0.0 3.1e+02 1.5 0.0 5.2 7 0 0 7 7 7 0 Bacterial macroglobulin domain 6 TMEM71 PF15121.6 GAM27464.1 - 0.13 11.9 4.2 32 4.1 0.1 3.7 3 0 0 3 3 3 0 TMEM71 protein family GP17 PF17420.2 GAM27464.1 - 0.39 10.9 4.5 1.2e+02 2.9 0.0 5.2 6 0 0 6 6 6 0 Superinfection exclusion gene product 17 DUF3659 PF12396.8 GAM27464.1 - 0.91 9.5 2.8 1.4e+02 2.5 0.0 5.0 6 0 0 6 6 6 0 Protein of unknown function (DUF3659) Dicty_spore_N PF04562.12 GAM27465.1 - 2.5e-25 89.4 25.9 2.5e-25 89.4 25.9 10.0 2 1 7 9 9 9 1 Dictyostelium spore coat protein, N terminus SPX PF03105.19 GAM27465.1 - 7.8 6.3 5.2 11 5.8 5.2 1.1 1 0 0 1 1 1 0 SPX domain Ank_2 PF12796.7 GAM27466.1 - 6.5e-05 23.4 0.1 0.0026 18.3 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM27466.1 - 9.3 7.0 7.1 2.8 8.6 0.1 3.9 5 1 1 6 6 6 0 Ankyrin repeats (many copies) AF-4 PF05110.13 GAM27467.1 - 0.015 13.5 3.6 0.017 13.3 3.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LPG_synthase_TM PF03706.13 GAM27468.1 - 0.23 11.0 0.0 0.23 11.0 0.0 2.7 2 1 1 3 3 3 0 Lysylphosphatidylglycerol synthase TM region COesterase PF00135.28 GAM27469.1 - 1.9e-113 380.1 0.1 5.8e-113 378.5 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM27469.1 - 4e-05 23.6 0.2 0.00015 21.7 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Skp1 PF01466.19 GAM27470.1 - 9.8e-05 22.4 0.0 0.00029 20.9 0.0 1.9 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GAM27470.1 - 0.0016 18.5 6.6 0.086 13.0 0.0 2.9 3 0 0 3 3 3 2 Skp1 family, tetramerisation domain SOG2 PF10428.9 GAM27470.1 - 0.12 11.6 32.4 0.03 13.6 20.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein RNase_PH PF01138.21 GAM27471.1 - 2.4e-33 115.4 0.1 3.3e-33 115.0 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAM27471.1 - 0.00019 21.4 0.1 0.0023 17.9 0.0 2.4 3 0 0 3 3 3 1 3' exoribonuclease family, domain 2 PDCD2_C PF04194.13 GAM27472.1 - 5.7e-30 104.7 33.5 1.4e-23 83.9 30.4 4.1 1 1 1 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Dehalogenase PF13486.6 GAM27472.1 - 0.0079 15.6 1.3 0.015 14.7 1.2 1.4 1 1 0 1 1 1 1 Reductive dehalogenase subunit A2L_zn_ribbon PF08792.10 GAM27472.1 - 0.032 14.0 3.8 11 5.9 0.1 3.6 3 0 0 3 3 3 0 A2L zinc ribbon domain TFIIS_C PF01096.18 GAM27472.1 - 1.1 9.2 6.1 24 4.9 0.3 3.3 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Presenilin PF01080.17 GAM27472.1 - 1.6 7.4 7.9 2.3 6.9 7.9 1.3 1 0 0 1 1 1 0 Presenilin Roughex PF06020.11 GAM27472.1 - 2 7.5 15.0 3.2 6.8 15.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Nop14 PF04147.12 GAM27472.1 - 3 5.9 21.0 4.2 5.5 21.0 1.1 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.10 GAM27472.1 - 3.3 8.4 22.2 0.11 13.1 10.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) SDA1 PF05285.12 GAM27472.1 - 7.7 5.8 23.3 10 5.4 23.3 1.2 1 0 0 1 1 1 0 SDA1 DUF755 PF05501.11 GAM27472.1 - 8.6 6.7 16.7 0.63 10.3 11.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Ras PF00071.22 GAM27473.1 - 1.3e-35 122.4 0.0 1.8e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM27473.1 - 1.8e-24 86.2 0.0 3.2e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM27473.1 - 1.2e-07 31.3 0.0 1.6e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM27473.1 - 9.2e-06 25.7 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAM27473.1 - 0.0019 17.6 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM27473.1 - 0.0022 17.6 0.0 0.016 14.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 GAM27473.1 - 0.0077 16.6 0.0 0.022 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAM27473.1 - 0.019 14.9 0.0 0.1 12.5 0.0 2.1 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 GAM27473.1 - 0.05 14.1 0.1 0.27 11.7 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 GAM27473.1 - 0.085 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Memo PF01875.17 GAM27474.1 - 1.1e-83 280.5 0.0 1.3e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein zf-Tim10_DDP PF02953.15 GAM27475.1 - 1.9e-13 49.8 3.1 2.3e-13 49.6 3.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.9 GAM27475.1 - 0.022 14.7 4.7 0.061 13.3 0.7 2.1 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Crust_neurohorm PF01147.17 GAM27475.1 - 0.041 13.7 0.2 0.053 13.3 0.2 1.2 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Pyr_redox_2 PF07992.14 GAM27477.1 - 2.7e-42 145.0 0.0 3.1e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM27477.1 - 1.2e-09 38.6 0.2 4.1e-09 36.9 0.2 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_C PF05199.13 GAM27477.1 - 0.044 14.3 0.1 0.59 10.7 0.0 2.4 2 0 0 2 2 2 0 GMC oxidoreductase DUF4461 PF14688.6 GAM27478.1 - 4.4e-26 92.4 0.1 5.8e-23 82.2 0.0 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4461) DUF4460 PF14687.6 GAM27478.1 - 3.1e-24 85.2 2.3 3.1e-24 85.2 2.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4457 PF14652.6 GAM27479.1 - 2.9e-153 509.9 7.7 2.3e-112 375.5 1.5 3.5 3 1 1 4 4 4 3 Domain of unknown function (DUF4457) DUF5000 PF16391.5 GAM27479.1 - 0.00047 20.3 0.5 0.68 10.0 0.0 5.2 6 0 0 6 6 6 1 Domain of unknown function Sad1_UNC PF07738.13 GAM27479.1 - 0.0036 17.3 0.0 6.4 6.8 0.0 3.6 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal Mrr_cat PF04471.12 GAM27480.1 - 1.1e-07 31.8 0.0 1.8e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease GCK PF07802.11 GAM27481.1 - 3.4e-06 27.4 0.7 4.8e-06 26.9 0.7 1.2 1 0 0 1 1 1 1 GCK domain CHCH PF06747.13 GAM27481.1 - 0.0044 17.1 3.0 0.007 16.5 3.0 1.4 1 0 0 1 1 1 1 CHCH domain SUIM_assoc PF16619.5 GAM27482.1 - 0.0048 16.9 1.7 0.014 15.4 1.7 1.9 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 LemA PF04011.12 GAM27482.1 - 0.014 15.2 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 LemA family DSX_dimer PF08828.10 GAM27482.1 - 0.046 13.4 0.2 0.1 12.3 0.2 1.6 1 0 0 1 1 1 0 Doublesex dimerisation domain Kelch_5 PF13854.6 GAM27483.1 - 1.7e-24 85.3 3.8 7.5e-09 35.4 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 GAM27483.1 - 2.7e-23 81.3 1.1 6.6e-08 32.0 0.0 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 GAM27483.1 - 8.7e-22 76.9 0.1 5.8e-08 32.8 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM27483.1 - 5.2e-21 74.2 3.9 2.4e-07 30.8 0.1 5.2 2 1 3 5 5 5 4 Kelch motif Kelch_4 PF13418.6 GAM27483.1 - 2.2e-19 69.2 0.2 0.00013 21.9 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM27483.1 - 4.5e-15 54.9 4.6 0.00015 21.6 0.1 5.1 5 0 0 5 5 5 3 Kelch motif UPF0225 PF17775.1 GAM27483.1 - 0.045 14.6 0.3 1.6 9.6 0.1 2.4 2 0 0 2 2 2 0 UPF0225 domain DUF5470 PF17564.2 GAM27483.1 - 0.047 13.9 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5470) bZIP_1 PF00170.21 GAM27484.1 - 8.9e-14 51.3 10.6 2.3e-13 50.0 10.6 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM27484.1 - 2e-06 27.8 12.7 6.5e-06 26.1 8.9 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAM27484.1 - 0.00035 21.0 5.0 0.00083 19.8 5.0 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Rootletin PF15035.6 GAM27484.1 - 0.018 15.1 5.2 0.039 14.0 5.2 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 GAM27484.1 - 0.063 13.9 0.3 0.21 12.2 0.3 1.9 1 0 0 1 1 1 0 Initiation control protein YabA DUF2730 PF10805.8 GAM27484.1 - 0.66 10.1 2.6 1.3 9.1 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) ATG16 PF08614.11 GAM27484.1 - 1 9.6 10.0 0.098 12.9 5.0 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) WD40 PF00400.32 GAM27485.1 - 3.5e-31 106.8 20.1 6.7e-08 33.1 1.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM27485.1 - 7.1e-18 64.7 1.1 0.00011 22.5 0.0 5.2 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM27485.1 - 3.3e-07 29.6 3.7 0.021 13.8 0.1 4.2 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAM27485.1 - 5e-05 23.3 3.2 0.055 13.4 0.0 3.2 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAM27485.1 - 0.0033 16.8 0.0 0.0079 15.6 0.0 1.7 2 1 0 2 2 2 1 WD40-like domain Frtz PF11768.8 GAM27485.1 - 0.0053 15.1 0.1 0.039 12.3 0.0 2.0 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 GAM27485.1 - 0.0064 15.5 2.1 0.057 12.3 0.4 2.7 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 GAM27485.1 - 0.015 14.6 1.4 2.4 7.4 0.0 3.4 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 GAM27485.1 - 0.016 13.8 4.5 0.08 11.6 0.5 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 GAM27485.1 - 0.035 14.1 1.7 54 3.9 0.1 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF5114 PF17141.4 GAM27485.1 - 0.12 13.0 0.4 5.8 7.5 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5114) PHTB1_N PF14727.6 GAM27485.1 - 0.12 11.7 0.1 1.9 7.7 0.0 2.0 1 1 1 2 2 2 0 PTHB1 N-terminus Pribosyltran PF00156.27 GAM27486.1 - 2.3e-12 46.7 0.0 3.8e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAM27486.1 - 2e-06 27.4 0.0 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_28 PF13521.6 GAM27487.1 - 6.4e-30 104.5 0.0 9.2e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain NCBP3 PF10309.9 GAM27487.1 - 0.005 16.7 0.2 0.027 14.3 0.2 2.0 1 1 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Bromodomain PF00439.25 GAM27488.1 - 2.6e-19 69.1 0.0 6.4e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 GAM27488.1 - 4.7e-19 68.3 2.3 4.7e-19 68.3 2.3 2.9 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation AHD PF17793.1 GAM27488.1 - 0.026 14.3 0.1 0.066 13.0 0.1 1.7 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Kelch_3 PF13415.6 GAM27489.1 - 2.1e-34 117.1 1.5 1.4e-12 47.5 0.0 6.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM27489.1 - 1.1e-32 111.8 0.5 1.9e-08 34.2 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM27489.1 - 8.7e-31 104.7 7.2 3.7e-08 33.0 0.1 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 GAM27489.1 - 1.3e-29 101.5 0.1 4.6e-08 32.5 0.0 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 GAM27489.1 - 3.6e-29 100.1 2.3 3.6e-06 27.1 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 GAM27489.1 - 8.3e-28 95.9 0.1 1.2e-06 28.4 0.0 5.4 5 0 0 5 5 5 5 Kelch motif MnmE_helical PF12631.7 GAM27491.1 - 3.4e-49 167.8 0.8 4.3e-49 167.5 0.8 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 GAM27491.1 - 7e-25 87.6 0.0 1.6e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 GAM27491.1 - 2.5e-19 69.4 0.0 6.4e-19 68.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAM27491.1 - 2.3e-08 34.3 0.2 0.00012 22.1 0.1 2.6 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 GAM27491.1 - 9.9e-07 28.4 0.0 2.6e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAM27491.1 - 0.00024 20.7 0.0 0.03 13.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 GAM27491.1 - 0.002 17.8 0.1 0.15 11.6 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 GAM27491.1 - 0.0029 17.5 0.3 0.12 12.3 0.0 2.7 1 1 2 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 GAM27491.1 - 0.003 18.1 2.7 0.038 14.5 2.8 2.3 1 1 0 1 1 1 1 ABC transporter Guanylate_kin PF00625.21 GAM27491.1 - 0.0052 16.5 0.2 0.076 12.7 0.0 2.4 2 0 0 2 2 2 1 Guanylate kinase AAA_16 PF13191.6 GAM27491.1 - 0.0073 16.7 0.5 0.18 12.2 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 GAM27491.1 - 0.0084 16.4 0.1 0.035 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM27491.1 - 0.024 15.2 0.0 0.087 13.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain MMR_HSR1_Xtn PF16897.5 GAM27491.1 - 0.054 13.5 0.3 19 5.3 0.1 3.3 2 1 0 2 2 2 0 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 GAM27491.1 - 0.095 13.0 0.1 0.85 9.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF4974 PF16344.5 GAM27491.1 - 0.13 12.3 0.5 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) HSP70 PF00012.20 GAM27492.1 - 6.5e-261 866.8 12.2 7.4e-261 866.6 12.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM27492.1 - 2.1e-15 56.4 0.4 4.5e-14 52.0 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GAM27492.1 - 0.0031 17.2 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 GAM27492.1 - 0.0041 16.2 0.2 0.02 13.9 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 GAM27492.1 - 0.012 14.9 0.1 0.027 13.7 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase PG_binding_4 PF12229.8 GAM27492.1 - 0.072 13.4 9.2 0.056 13.7 6.6 2.2 2 0 0 2 2 2 0 Putative peptidoglycan binding domain MutS_III PF05192.18 GAM27492.1 - 1.1 9.4 4.2 8.3 6.6 0.0 2.3 2 0 0 2 2 2 0 MutS domain III TRAF_BIRC3_bd PF16673.5 GAM27492.1 - 7.1 6.5 7.7 9.5 6.1 1.0 3.5 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain AAA_2 PF07724.14 GAM27493.1 - 3.8e-05 23.9 0.0 9e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAM27493.1 - 0.0041 17.4 1.5 0.1 12.8 0.4 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAM27493.1 - 0.01 15.8 0.0 0.12 12.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 GAM27493.1 - 0.016 15.6 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM27493.1 - 0.025 15.0 0.1 1.2 9.5 0.1 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 GAM27493.1 - 0.033 14.2 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2559 PF10832.8 GAM27493.1 - 0.038 14.1 0.1 0.089 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) HSP20 PF00011.21 GAM27494.1 - 4.3e-20 71.8 0.0 5e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM27494.1 - 4.3e-08 32.6 0.0 5.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA GTP_EFTU PF00009.27 GAM27495.1 - 1.4e-44 152.0 0.2 2.1e-44 151.4 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAM27495.1 - 7.4e-27 93.9 2.7 3e-26 91.9 0.5 2.6 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAM27495.1 - 7.6e-07 29.4 2.3 1.3e-06 28.7 0.8 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAM27495.1 - 0.00027 21.0 0.6 0.0023 18.0 0.2 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAM27495.1 - 0.06 12.5 0.0 0.22 10.7 0.0 1.9 1 1 1 2 2 2 0 G-protein alpha subunit DUF5525 PF17663.1 GAM27495.1 - 0.6 8.1 15.8 0.82 7.7 15.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Fumble PF03630.14 GAM27496.1 - 2.3e-130 434.6 1.1 2.6e-130 434.4 1.1 1.0 1 0 0 1 1 1 1 Fumble Lipase_3 PF01764.25 GAM27497.1 - 1.1e-27 96.6 0.0 1.4e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GAM27497.1 - 0.0002 22.0 0.2 0.00033 21.3 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM27497.1 - 0.0098 15.2 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 GAM27497.1 - 0.012 15.4 0.1 0.053 13.3 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.14 GAM27497.1 - 0.018 14.5 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAM27497.1 - 0.021 14.5 0.4 0.034 13.9 0.2 1.3 1 1 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 GAM27497.1 - 0.034 13.7 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 GAM27498.1 - 7.4e-30 103.7 0.0 1.1e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.12 GAM27498.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF2013 PF09431.10 GAM27500.1 - 2.5e-17 63.3 1.9 5.6e-17 62.2 1.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) CODH_A_N PF18537.1 GAM27500.1 - 0.00083 19.3 0.1 0.3 11.1 0.0 2.6 1 1 1 2 2 2 2 Carbon monoxide dehydrogenase subunit alpha N-terminal domain DUF2373 PF10180.9 GAM27501.1 - 5e-20 71.1 0.5 5e-20 71.1 0.5 2.2 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) JmjC PF02373.22 GAM27502.1 - 1.3e-12 48.1 0.0 1.3e-12 48.1 0.0 3.2 2 1 0 2 2 2 1 JmjC domain, hydroxylase PWWP PF00855.17 GAM27502.1 - 0.013 15.9 0.0 0.013 15.9 0.0 2.2 2 0 0 2 2 2 0 PWWP domain GPI PF06560.11 GAM27502.1 - 0.054 12.8 0.9 0.11 11.7 0.3 1.8 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.11 GAM27502.1 - 0.079 12.7 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 Cupin domain PAT1 PF09770.9 GAM27502.1 - 0.42 8.8 22.6 0.68 8.1 22.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 E2F_TDP PF02319.20 GAM27503.1 - 5.1e-25 87.3 0.3 9e-12 44.9 0.0 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 GAM27503.1 - 0.24 11.3 1.1 0.6 10.0 0.0 2.1 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB DUF4573 PF15140.6 GAM27504.1 - 4.4e-12 46.2 17.4 6.4e-07 29.3 9.1 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4573) PRKCSH_1 PF13015.6 GAM27504.1 - 0.00012 21.8 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PLDc_2 PF13091.6 GAM27505.1 - 1.1e-11 44.8 0.0 0.00018 21.4 0.0 3.1 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAM27505.1 - 0.0076 16.4 0.5 0.0076 16.4 0.5 2.4 3 0 0 3 3 3 1 Phospholipase D Active site motif Vitelline_membr PF10542.9 GAM27505.1 - 0.095 12.6 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region CBS PF00571.28 GAM27507.1 - 8.8e-24 83.7 5.4 2e-06 28.1 0.0 4.2 4 0 0 4 4 4 4 CBS domain RBD PF02196.15 GAM27507.1 - 0.088 12.9 0.0 4.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Raf-like Ras-binding domain F-box PF00646.33 GAM27508.1 - 0.00018 21.3 1.2 0.00047 19.9 0.2 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 GAM27508.1 - 0.0024 17.7 1.7 0.0045 16.8 0.6 2.0 2 0 0 2 2 2 1 F-box-like Sdh_cyt PF01127.22 GAM27509.1 - 3.1e-21 75.6 2.2 4.3e-21 75.2 2.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Voltage_CLC PF00654.20 GAM27511.1 - 1.2e-97 327.4 18.3 1.2e-97 327.4 18.3 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 GAM27511.1 - 4.3e-13 49.5 0.8 4.2e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain RTP1_C1 PF10363.9 GAM27512.1 - 0.0049 17.0 0.3 0.16 12.2 0.0 3.2 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Proteasom_PSMB PF10508.9 GAM27512.1 - 0.23 9.9 9.0 1.9 6.9 0.0 3.2 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT PF02985.22 GAM27512.1 - 0.34 11.3 9.9 3.9 8.0 0.1 6.1 7 1 1 8 8 8 0 HEAT repeat DcpS_C PF11969.8 GAM27513.1 - 1.3e-26 93.3 2.3 2.6e-26 92.3 2.3 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 GAM27513.1 - 3.1e-15 56.7 0.5 6.6e-15 55.6 0.5 1.6 1 0 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 GAM27513.1 - 1.2e-09 38.4 1.1 3.5e-09 37.0 1.1 1.9 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger FHA_2 PF17913.1 GAM27513.1 - 0.00041 20.5 0.1 0.0015 18.8 0.1 2.0 1 0 0 1 1 1 1 FHA domain zf-C2H2_4 PF13894.6 GAM27513.1 - 0.019 15.8 0.9 0.063 14.1 0.9 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM27513.1 - 0.043 14.3 0.6 0.14 12.7 0.6 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Spermine_synth PF01564.17 GAM27513.1 - 0.043 13.2 0.1 0.082 12.3 0.1 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain zf-C2H2_6 PF13912.6 GAM27513.1 - 0.11 12.5 0.3 0.3 11.1 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1084 PF06454.11 GAM27514.1 - 1.3 8.3 28.0 3.4 7.0 27.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1084) LRR_4 PF12799.7 GAM27515.1 - 0.0094 16.3 7.4 0.15 12.6 0.4 4.8 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM27515.1 - 0.01 15.6 7.5 0.044 13.6 0.4 4.6 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 GAM27515.1 - 0.13 12.9 3.0 39 5.3 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 GAM27515.1 - 0.53 10.5 18.6 0.47 10.6 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich repeat Histone PF00125.24 GAM27516.1 - 2.2e-50 170.4 1.8 2.4e-50 170.3 1.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAM27516.1 - 2.1e-05 24.6 0.2 3.6e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAM27516.1 - 0.0002 21.6 0.1 0.00032 21.0 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 GAM27516.1 - 0.00057 20.5 0.3 0.00069 20.2 0.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 GAM27516.1 - 0.036 14.1 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SET PF00856.28 GAM27517.1 - 6.5e-23 82.0 0.1 6.5e-23 82.0 0.1 3.7 2 2 0 2 2 2 1 SET domain AWS PF17907.1 GAM27517.1 - 1.9e-10 40.6 7.0 1.9e-10 40.6 7.0 1.7 2 0 0 2 2 2 1 AWS domain DUF3915 PF13054.6 GAM27517.1 - 0.28 11.2 8.9 0.046 13.7 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) T2SSF PF00482.23 GAM27518.1 - 0.028 14.4 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF489 PF04356.12 GAM27518.1 - 0.28 11.2 6.4 0.52 10.3 0.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF489) OmpH PF03938.14 GAM27518.1 - 2.5 8.5 39.7 0.18 12.1 8.4 4.1 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) Cnd1 PF12717.7 GAM27519.1 - 2.3e-07 31.0 4.6 0.0014 18.7 0.3 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAM27519.1 - 0.0022 18.1 8.2 16 6.1 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat Vac14_Fab1_bd PF12755.7 GAM27519.1 - 0.012 16.2 0.9 15 6.3 0.1 3.3 1 1 4 5 5 5 0 Vacuolar 14 Fab1-binding region DUF1722 PF08349.11 GAM27520.1 - 0.056 13.7 1.6 24 5.3 0.0 3.4 4 1 0 4 4 4 0 Protein of unknown function (DUF1722) RmuC PF02646.16 GAM27520.1 - 0.065 12.4 1.3 2.3 7.3 0.1 2.4 2 0 0 2 2 2 0 RmuC family IcmF-related PF06761.12 GAM27520.1 - 0.086 12.3 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing PX PF00787.24 GAM27521.1 - 9.3e-11 41.7 0.3 9.3e-11 41.7 0.3 2.9 3 0 0 3 3 3 1 PX domain Dynamin_N PF00350.23 GAM27521.1 - 1.3e-05 25.3 0.4 1.3e-05 25.3 0.4 4.1 3 3 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 GAM27521.1 - 0.0011 19.1 2.2 0.0075 16.3 0.1 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Vps36_ESCRT-II PF11605.8 GAM27521.1 - 0.04 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Kelch_3 PF13415.6 GAM27522.1 - 8.4e-39 131.2 16.7 1.8e-09 37.6 0.4 7.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM27522.1 - 1.6e-36 123.6 6.0 1.8e-08 33.8 0.1 5.8 5 0 0 5 5 5 5 Kelch motif RasGEF PF00617.19 GAM27522.1 - 4.7e-36 124.6 0.8 4.7e-36 124.6 0.8 2.1 2 0 0 2 2 2 1 RasGEF domain Kelch_4 PF13418.6 GAM27522.1 - 9.6e-34 115.2 13.3 3.3e-07 30.2 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM27522.1 - 1.7e-30 104.2 14.1 1.8e-06 28.0 0.2 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 GAM27522.1 - 2.4e-28 97.6 12.3 9.4e-08 31.9 0.1 6.0 6 0 0 6 6 6 5 Kelch motif RasGEF_N PF00618.20 GAM27522.1 - 1.3e-22 80.0 2.1 1.7e-22 79.6 0.3 2.2 3 0 0 3 3 3 1 RasGEF N-terminal motif Kelch_2 PF07646.15 GAM27522.1 - 3.2e-22 77.6 8.0 1.9e-05 24.5 0.1 6.6 6 0 0 6 6 6 4 Kelch motif DUF2157 PF09925.9 GAM27523.1 - 0.057 13.2 0.1 0.75 9.6 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3463 PF11946.8 GAM27524.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) TPK_catalytic PF04263.16 GAM27525.1 - 1e-32 112.7 0.0 1.4e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 GAM27525.1 - 3.3e-16 58.7 0.4 7.3e-16 57.7 0.4 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CMAS PF02353.20 GAM27526.1 - 1e-86 290.7 0.0 1.3e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 GAM27526.1 - 7.3e-11 42.6 0.0 2e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM27526.1 - 9.2e-11 42.3 0.0 2.1e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM27526.1 - 1.4e-10 41.3 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM27526.1 - 8.4e-09 35.4 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM27526.1 - 1.2e-06 29.2 0.0 3e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM27526.1 - 0.0022 17.5 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.17 GAM27526.1 - 0.0041 16.3 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Cons_hypoth95 PF03602.15 GAM27526.1 - 0.0061 16.2 0.0 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical protein 95 DOT1 PF08123.13 GAM27526.1 - 0.0084 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_2 PF00891.18 GAM27526.1 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 GAM27526.1 - 0.0098 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 GAM27526.1 - 0.03 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 GAM27526.1 - 0.038 13.9 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 GAM27526.1 - 0.086 13.9 0.0 0.34 12.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_PK PF05891.12 GAM27526.1 - 0.096 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Amino_oxidase PF01593.24 GAM27527.1 - 7e-23 81.6 0.0 3.3e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM27527.1 - 4e-17 62.2 0.2 9.6e-17 61.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM27527.1 - 7.8e-09 35.6 0.1 4.5e-08 33.1 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM27527.1 - 4.3e-07 29.4 1.8 6.2e-07 28.9 1.8 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAM27527.1 - 1.2e-05 24.7 0.2 4.7e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAM27527.1 - 0.00013 21.4 0.2 0.0002 20.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM27527.1 - 0.00014 22.3 0.3 0.00053 20.5 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAM27527.1 - 0.00048 19.0 0.6 0.00089 18.1 0.5 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 GAM27527.1 - 0.0012 18.0 1.6 0.0023 17.1 1.6 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 GAM27527.1 - 0.0015 17.8 0.8 0.0024 17.1 0.8 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAM27527.1 - 0.0048 16.2 0.2 0.038 13.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAM27527.1 - 0.0048 16.8 1.3 0.0081 16.1 1.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAM27527.1 - 0.0049 16.1 0.7 0.026 13.8 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 GAM27527.1 - 0.021 14.8 0.2 3.4 7.6 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 GAM27527.1 - 0.026 13.3 0.3 0.044 12.6 0.1 1.4 1 1 0 1 1 1 0 MCRA family ApbA PF02558.16 GAM27527.1 - 0.031 13.9 0.7 0.068 12.8 0.5 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FMO-like PF00743.19 GAM27527.1 - 0.036 12.5 0.0 0.053 11.9 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like eIF3m_C_helix PF18005.1 GAM27527.1 - 0.096 12.4 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix UDPG_MGDP_dh_N PF03721.14 GAM27527.1 - 0.12 12.0 0.6 0.2 11.2 0.6 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 GAM27527.1 - 0.14 11.4 1.0 0.21 10.9 1.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LRR_4 PF12799.7 GAM27528.1 - 0.00098 19.5 0.9 0.00098 19.5 0.9 4.6 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM27528.1 - 0.024 15.2 14.2 3.7 8.5 0.2 6.3 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 GAM27528.1 - 0.2 11.4 14.9 0.03 14.1 4.4 4.3 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 GAM27530.1 - 0.00085 19.2 16.4 0.0071 16.3 0.6 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 GAM27530.1 - 0.016 15.6 5.2 1 9.9 1.8 3.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) ADP_PFK_GK PF04587.15 GAM27531.1 - 0.088 11.4 0.0 0.089 11.4 0.0 1.0 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region PX PF00787.24 GAM27532.1 - 0.096 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 PX domain PH PF00169.29 GAM27533.1 - 2.3e-17 63.4 1.8 3.8e-17 62.7 0.1 2.1 3 0 0 3 3 3 1 PH domain PH_8 PF15409.6 GAM27533.1 - 1.4e-05 25.2 0.1 4.1e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAM27533.1 - 4.1e-05 23.9 0.5 4.1e-05 23.9 0.5 2.9 2 2 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 GAM27533.1 - 8.9e-05 22.7 0.0 0.00031 21.0 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 GAM27533.1 - 0.00098 19.2 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 GAM27533.1 - 0.036 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 PH domain PH_9 PF15410.6 GAM27533.1 - 0.05 14.0 0.1 0.76 10.2 0.1 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain SepZ PF06066.11 GAM27533.1 - 0.1 12.8 0.0 0.1 12.8 0.0 2.6 3 0 0 3 3 3 0 SepZ Transketolase_N PF00456.21 GAM27534.1 - 7.9e-106 353.8 0.1 1.2e-105 353.1 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAM27534.1 - 1.5e-42 145.2 0.0 3.6e-42 144.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAM27534.1 - 9.2e-13 48.2 0.0 2.9e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAM27534.1 - 2.3e-06 27.0 0.1 1.5e-05 24.4 0.0 2.3 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 GAM27534.1 - 0.00046 20.0 0.1 0.0056 16.5 0.2 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ras PF00071.22 GAM27535.1 - 1.5e-41 141.7 0.0 1.9e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM27535.1 - 1.8e-31 108.9 0.0 2.8e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM27535.1 - 2.4e-12 46.6 0.0 3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM27535.1 - 4.6e-06 26.2 0.0 6.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM27535.1 - 0.0028 17.1 0.0 0.012 15.1 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM27535.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM27535.1 - 0.02 14.4 0.0 0.094 12.2 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TerD PF02342.18 GAM27536.1 - 2.1e-69 232.8 0.0 2.7e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 TerD domain TIG PF01833.24 GAM27537.1 - 1.4e-21 76.4 44.6 3e-08 33.6 1.0 7.6 8 0 0 8 8 8 5 IPT/TIG domain Lectin_C PF00059.21 GAM27537.1 - 1.6e-06 28.8 0.2 1.7e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 Lectin C-type domain EGF_2 PF07974.13 GAM27537.1 - 0.00052 20.3 9.7 0.0017 18.7 9.7 1.9 1 0 0 1 1 1 1 EGF-like domain LapA_dom PF06305.11 GAM27537.1 - 0.006 16.4 0.4 0.012 15.5 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain EGF PF00008.27 GAM27537.1 - 0.2 12.0 6.3 0.97 9.8 6.3 2.2 1 0 0 1 1 1 0 EGF-like domain I-EGF_1 PF18372.1 GAM27537.1 - 0.52 10.4 7.0 1.6 8.9 7.0 1.9 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EF-hand_9 PF14658.6 GAM27538.1 - 0.095 13.0 0.0 0.45 10.9 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain AA_synth PF06684.11 GAM27538.1 - 0.14 11.7 0.1 0.58 9.7 0.1 2.1 1 0 0 1 1 1 0 Amino acid synthesis Baculo_LEF5 PF04838.12 GAM27538.1 - 0.76 9.8 3.9 0.52 10.4 0.1 2.7 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 XPC-binding PF09280.11 GAM27538.1 - 1.7 8.4 12.3 0.44 10.3 0.1 5.7 6 0 0 6 6 6 0 XPC-binding domain Dak2 PF02734.17 GAM27538.1 - 2.1 8.2 9.1 7.5 6.4 0.0 4.4 4 0 0 4 4 4 0 DAK2 domain Stealth_CR2 PF11380.8 GAM27539.1 - 5e-35 120.0 1.1 2.4e-34 117.8 0.2 2.3 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 GAM27539.1 - 8e-14 51.1 0.3 1.7e-13 50.0 0.3 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 GAM27539.1 - 9e-09 35.1 1.8 1.4e-08 34.5 0.0 2.3 3 0 0 3 3 3 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 GAM27539.1 - 8.2e-07 28.8 1.8 1.4e-06 28.1 1.1 1.8 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Metallophos PF00149.28 GAM27540.1 - 2.2e-11 44.6 1.0 2.2e-11 44.6 1.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SapB_1 PF05184.15 GAM27540.1 - 0.00064 19.7 0.3 0.0026 17.7 0.3 2.1 1 0 0 1 1 1 1 Saposin-like type B, region 1 SapB_2 PF03489.17 GAM27540.1 - 0.0011 19.0 3.0 0.0049 16.9 0.1 3.3 3 0 0 3 3 3 1 Saposin-like type B, region 2 TehB PF03848.14 GAM27540.1 - 0.013 14.9 0.5 0.032 13.6 0.5 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB HCV_env PF01539.17 GAM27540.1 - 0.076 12.7 0.3 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 Peptidase_S8 PF00082.22 GAM27541.1 - 6.3e-41 140.6 2.2 1.1e-40 139.8 2.2 1.4 1 0 0 1 1 1 1 Subtilase family AATase PF07247.12 GAM27542.1 - 0.01 14.4 0.4 0.016 13.8 0.4 1.3 1 0 0 1 1 1 0 Alcohol acetyltransferase TrbI_Ftype PF09677.10 GAM27542.1 - 0.044 14.1 0.2 0.079 13.3 0.2 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) TetR_C_18 PF17923.1 GAM27542.1 - 0.08 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain cNMP_binding PF00027.29 GAM27543.1 - 2.7e-45 152.4 0.0 3.4e-22 78.3 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 GAM27543.1 - 0.038 13.7 0.1 0.099 12.4 0.1 1.7 1 0 0 1 1 1 0 Cupin domain Cupin_3 PF05899.12 GAM27543.1 - 0.059 13.1 0.3 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) ThiS PF02597.20 GAM27544.1 - 2.6e-12 47.2 0.0 4.6e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 ThiS family DUF1077 PF06417.12 GAM27545.1 - 4.9e-37 126.6 2.9 6.5e-37 126.1 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) zf-RING_2 PF13639.6 GAM27546.1 - 8.4e-12 45.2 8.2 8.4e-12 45.2 8.2 2.0 2 0 0 2 2 1 1 Ring finger domain CUE PF02845.16 GAM27546.1 - 5.9e-11 41.8 0.0 1.6e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 CUE domain zf-C3HC4_2 PF13923.6 GAM27546.1 - 4.1e-09 36.1 8.0 9.3e-09 35.0 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM27546.1 - 3.8e-08 33.2 4.3 9.2e-08 32.0 4.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAM27546.1 - 5.7e-08 32.5 4.4 1e-07 31.7 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM27546.1 - 1.2e-07 31.5 7.2 1.2e-07 31.5 7.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM27546.1 - 1.3e-06 28.6 11.8 1.3e-06 28.6 11.8 3.2 3 1 0 3 3 3 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAM27546.1 - 8.4e-06 25.6 6.1 1.9e-05 24.4 6.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAM27546.1 - 1.9e-05 24.5 6.2 1.9e-05 24.5 6.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 GAM27546.1 - 5.2e-05 22.9 4.0 5.2e-05 22.9 4.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 GAM27546.1 - 0.00054 19.5 5.2 0.00054 19.5 5.2 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 GAM27546.1 - 0.0013 18.8 4.7 0.0031 17.6 4.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 GAM27546.1 - 0.0045 17.0 5.9 0.0045 17.0 5.9 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 GAM27546.1 - 0.075 13.2 7.9 0.17 12.0 7.9 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 GAM27546.1 - 0.23 11.7 5.5 0.66 10.2 5.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 GAM27546.1 - 0.59 10.0 4.7 1.3 8.9 4.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SR-25 PF10500.9 GAM27546.1 - 2.4 7.7 20.4 0.037 13.6 11.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-RING-like PF08746.11 GAM27546.1 - 3.6 8.0 7.6 9.2 6.7 7.6 1.7 1 0 0 1 1 1 0 RING-like domain RNA_pol_Rpb2_6 PF00562.28 GAM27547.1 - 3.4e-120 401.7 0.0 5.4e-120 401.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAM27547.1 - 1.3e-50 171.7 0.4 2e-50 171.2 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 GAM27547.1 - 6.6e-32 109.8 0.7 1.5e-31 108.7 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 GAM27547.1 - 5e-25 87.6 0.4 1.4e-24 86.1 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 GAM27547.1 - 6.4e-24 84.6 0.8 1.9e-23 83.1 1.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 GAM27547.1 - 5.4e-20 71.3 0.0 1.1e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 GAM27547.1 - 2.3e-10 40.9 0.2 7.4e-10 39.2 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Cpn60_TCP1 PF00118.24 GAM27548.1 - 3.7e-94 316.1 0.4 4.8e-94 315.7 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family 2OG-FeII_Oxy PF03171.20 GAM27549.1 - 5e-16 59.0 0.2 9.6e-16 58.1 0.2 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 GAM27549.1 - 5.3e-13 49.8 1.0 3e-12 47.3 1.0 2.1 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Cupin_2 PF07883.11 GAM27550.1 - 2.1e-11 43.3 0.2 2.1e-11 43.3 0.2 1.5 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 GAM27550.1 - 4.4e-06 26.4 0.0 6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 GAM27550.1 - 0.00011 22.2 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DMSP_lyase PF16867.5 GAM27550.1 - 0.046 13.3 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase FdtA PF05523.11 GAM27550.1 - 0.065 13.0 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal JmjC PF02373.22 GAM27550.1 - 0.095 13.1 0.2 0.21 12.0 0.2 1.8 1 1 0 1 1 1 0 JmjC domain, hydroxylase Esterase_phd PF10503.9 GAM27552.1 - 0.00042 19.9 0.1 0.039 13.4 0.0 2.3 2 0 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S9 PF00326.21 GAM27552.1 - 0.14 11.6 0.0 15 5.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.12 GAM27552.1 - 0.22 10.2 0.0 0.4 9.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Pkinase PF00069.25 GAM27553.1 - 1e-69 234.9 0.0 3.7e-69 233.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27553.1 - 2.1e-31 109.1 0.0 6.2e-31 107.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM27553.1 - 4.8e-12 45.8 0.0 2.1e-11 43.7 0.0 1.9 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 GAM27553.1 - 0.00011 21.8 0.1 0.00029 20.5 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAM27553.1 - 0.0012 18.2 0.5 0.0025 17.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 GAM27553.1 - 0.022 14.3 2.3 0.024 14.1 0.2 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DivIC PF04977.15 GAM27553.1 - 0.21 11.4 11.7 1.1 9.1 1.8 2.7 2 0 0 2 2 2 0 Septum formation initiator CutC PF03932.14 GAM27554.1 - 2.7e-45 154.3 0.0 3.3e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 CutC family FAD_binding_3 PF01494.19 GAM27555.1 - 4.2e-20 72.3 0.0 5.5e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 GAM27555.1 - 6.9e-10 38.4 0.0 2.3e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 GAM27555.1 - 6.6e-09 35.8 0.0 0.0039 16.8 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAM27555.1 - 1.2e-06 28.9 0.1 6.7e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM27555.1 - 7.3e-06 25.4 0.4 0.0012 18.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAM27555.1 - 1.5e-05 25.1 0.1 5.8e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAM27555.1 - 0.00018 20.8 0.1 0.00063 19.1 0.0 1.9 2 1 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAM27555.1 - 0.0011 18.1 0.1 0.24 10.4 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 GAM27555.1 - 0.012 14.4 0.0 0.022 13.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 GAM27555.1 - 0.014 14.5 0.0 0.033 13.3 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 GAM27555.1 - 0.023 14.3 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 GAM27555.1 - 0.054 12.8 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3523 PF12037.8 GAM27555.1 - 0.14 11.5 0.3 0.32 10.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) Myb_DNA-binding PF00249.31 GAM27557.1 - 1.9e-10 40.8 0.0 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM27557.1 - 0.002 18.0 1.0 0.0053 16.6 0.6 1.9 1 1 0 1 1 1 1 Myb DNA-binding like UVR PF02151.19 GAM27558.1 - 0.025 14.3 0.5 0.025 14.3 0.5 3.6 3 0 0 3 3 3 0 UvrB/uvrC motif Alpha_kinase PF02816.18 GAM27559.1 - 2.7e-57 193.9 0.1 4.3e-57 193.2 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.32 GAM27559.1 - 2e-20 72.7 12.8 0.00095 19.9 0.1 6.9 6 1 1 7 7 7 4 WD domain, G-beta repeat WD40_like PF17005.5 GAM27559.1 - 4.4e-09 36.1 0.8 9.7e-09 35.0 0.7 1.5 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 GAM27559.1 - 1.2e-07 30.7 5.1 0.0037 16.0 0.4 3.3 2 1 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAM27559.1 - 0.00035 20.8 2.2 0.39 11.0 0.3 3.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAM27559.1 - 0.32 9.9 4.2 1.7 7.6 0.2 2.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIA PF03153.13 GAM27559.1 - 0.57 10.1 26.8 0.83 9.6 26.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 GAM27559.1 - 8.8 4.9 17.8 13 4.3 17.8 1.1 1 0 0 1 1 1 0 Hamartin protein Polysacc_deac_1 PF01522.21 GAM27560.1 - 2.9e-20 72.4 0.2 1.5e-18 66.9 0.2 2.3 1 1 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 GAM27560.1 - 0.0015 17.8 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase SR-25 PF10500.9 GAM27560.1 - 1.4 8.4 15.3 7.1 6.2 0.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ketoacyl-synt PF00109.26 GAM27561.1 - 3e-79 266.2 1.4 2.6e-76 256.5 0.0 3.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAM27561.1 - 3.1e-57 194.5 0.0 7.2e-57 193.3 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 GAM27561.1 - 1.4e-42 145.6 0.1 4.6e-42 143.9 0.1 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 GAM27561.1 - 2.1e-40 138.8 0.0 3.4e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAM27561.1 - 1e-33 115.8 0.3 1e-31 109.4 0.0 3.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Chal_sti_synt_C PF02797.15 GAM27561.1 - 5.6e-24 84.9 0.1 1.2e-23 83.8 0.1 1.6 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ADH_zinc_N PF00107.26 GAM27561.1 - 5.7e-20 71.6 0.0 6.5e-19 68.2 0.1 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Chal_sti_synt_N PF00195.19 GAM27561.1 - 2.1e-17 63.3 1.5 2.8e-17 62.9 0.3 1.8 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain ADH_zinc_N_2 PF13602.6 GAM27561.1 - 2.4e-14 54.5 0.0 1.6e-13 51.8 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase FAE1_CUT1_RppA PF08392.12 GAM27561.1 - 2.8e-14 53.1 1.6 5.2e-14 52.2 0.3 2.1 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein adh_short_C2 PF13561.6 GAM27561.1 - 1.9e-11 44.0 0.1 6.8e-11 42.2 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 GAM27561.1 - 1.1e-09 38.5 0.1 2.6e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAM27561.1 - 8.1e-09 35.9 0.0 3.5e-08 33.9 0.0 2.2 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAM27561.1 - 2.1e-08 33.8 0.3 2.1e-08 33.8 0.3 2.5 2 0 0 2 2 2 1 short chain dehydrogenase ACP_syn_III_C PF08541.10 GAM27561.1 - 3.1e-08 33.7 0.1 0.0002 21.5 0.0 3.9 3 0 0 3 3 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ADH_N PF08240.12 GAM27561.1 - 5e-08 32.8 0.1 1.8e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 GAM27561.1 - 7.8e-06 25.4 4.7 3.2e-05 23.4 0.1 3.2 3 0 0 3 3 3 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 GAM27561.1 - 0.00021 21.1 8.5 0.0033 17.3 1.1 3.5 3 1 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HMA PF00403.26 GAM27561.1 - 0.064 13.7 0.1 0.19 12.2 0.1 1.8 1 0 0 1 1 1 0 Heavy-metal-associated domain Doppel PF11466.8 GAM27562.1 - 0.074 12.7 0.3 0.19 11.4 0.3 1.7 1 0 0 1 1 1 0 Prion-like protein Doppel SPG48 PF14764.6 GAM27562.1 - 0.46 11.0 3.5 2.8 8.4 0.0 3.8 3 2 1 4 4 4 0 AP-5 complex subunit, vesicle trafficking HEAT_2 PF13646.6 GAM27563.1 - 2e-06 28.1 0.1 4e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 GAM27563.1 - 0.0011 19.1 3.3 0.011 16.0 0.1 3.4 4 0 0 4 4 4 1 HEAT repeat RTP1_C1 PF10363.9 GAM27563.1 - 0.0032 17.6 0.2 0.0051 17.0 0.2 1.3 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 GAM27563.1 - 0.0049 16.8 1.4 0.0049 16.8 1.4 1.6 2 0 0 2 2 2 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 GAM27563.1 - 0.031 14.9 0.1 0.056 14.1 0.1 1.4 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 GAM27563.1 - 0.14 12.2 0.8 0.23 11.5 0.8 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 API5 PF05918.11 GAM27563.1 - 4.2 6.1 10.0 0.032 13.1 0.6 1.9 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) DEAD PF00270.29 GAM27564.1 - 3e-39 134.6 0.1 6.1e-39 133.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM27564.1 - 1.7e-28 99.2 1.2 1.7e-28 99.2 1.2 3.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM27564.1 - 1.6e-06 28.2 0.0 1.6e-06 28.2 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit MAGSP PF03082.14 GAM27565.1 - 0.017 14.7 0.1 0.022 14.4 0.1 1.1 1 0 0 1 1 1 0 Male accessory gland secretory protein DUF1664 PF07889.12 GAM27566.1 - 0.052 13.6 1.8 0.96 9.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GAM27566.1 - 0.053 13.6 5.8 0.11 12.5 1.5 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1748 PF08520.10 GAM27567.1 - 4.9e-10 39.2 0.0 6.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MRP-L20 PF12824.7 GAM27568.1 - 6.1e-05 23.2 3.0 6.1e-05 23.2 3.0 2.4 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_38 PF13936.6 GAM27568.1 - 0.0056 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Neugrin PF06413.11 GAM27568.1 - 0.038 14.0 5.4 0.24 11.4 5.4 2.3 1 1 0 1 1 1 0 Neugrin CRT10 PF08728.10 GAM27568.1 - 4.4 5.3 11.2 6.4 4.8 11.2 1.3 1 0 0 1 1 1 0 CRT10 Myb_DNA-binding PF00249.31 GAM27569.1 - 4.6e-12 45.9 0.1 1.3e-07 31.7 0.0 3.1 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM27569.1 - 9.4e-05 22.6 0.6 0.78 10.0 0.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM27569.1 - 0.0026 17.6 0.4 0.0026 17.6 0.4 3.8 3 1 1 4 4 4 1 Myb DNA-binding like Calici_MSP PF05752.11 GAM27569.1 - 0.016 15.0 1.0 0.055 13.3 1.0 1.8 1 0 0 1 1 1 0 Calicivirus minor structural protein GPS2_interact PF15784.5 GAM27569.1 - 0.91 10.0 8.5 0.12 12.8 0.4 3.2 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain Peptidase_M20 PF01546.28 GAM27570.1 - 5.6e-31 107.8 0.0 8.7e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM27570.1 - 4.4e-14 52.3 0.0 7.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAM27570.1 - 7.7e-05 22.5 0.0 0.00032 20.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 YEATS PF03366.16 GAM27571.1 - 2.3e-28 98.0 0.1 5.9e-28 96.7 0.0 1.8 2 0 0 2 2 2 1 YEATS family DUF4763 PF15960.5 GAM27571.1 - 0.037 13.3 13.0 0.055 12.8 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Curto_V2 PF07325.11 GAM27571.1 - 4.7 7.1 5.9 6.9 6.6 1.9 2.2 1 1 1 2 2 2 0 Curtovirus V2 protein LPMO_10 PF03067.15 GAM27572.1 - 5.9e-25 89.1 1.0 6.9e-25 88.8 1.0 1.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Methyltransf_2 PF00891.18 GAM27573.1 - 6.3e-23 81.2 0.3 6.2e-21 74.7 0.0 2.3 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_31 PF13847.6 GAM27573.1 - 2.1e-05 24.4 0.1 4.7e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM27573.1 - 5.9e-05 22.7 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 GAM27573.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM27573.1 - 0.00019 22.1 0.0 0.00042 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAM27573.1 - 0.00096 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAM27573.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 GAM27573.1 - 0.017 15.9 0.0 0.091 13.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Acetyltransf_19 PF18015.1 GAM27573.1 - 0.021 15.0 0.1 0.076 13.2 0.1 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SgrR_N PF12793.7 GAM27573.1 - 0.07 13.4 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term LRR_6 PF13516.6 GAM27574.1 - 1.5e-42 140.0 39.5 9.6e-06 25.3 0.2 13.8 14 0 0 14 14 14 10 Leucine Rich repeat LRR_4 PF12799.7 GAM27574.1 - 0.00021 21.6 30.2 0.29 11.6 0.1 8.7 4 2 5 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM27574.1 - 0.043 13.6 32.1 0.72 9.7 3.5 9.1 4 4 2 6 6 6 0 Leucine rich repeat LRR_1 PF00560.33 GAM27574.1 - 0.084 13.5 21.9 22 6.1 0.0 9.2 11 0 0 11 11 11 0 Leucine Rich Repeat FliE PF02049.18 GAM27575.1 - 0.35 11.0 4.5 1.4 9.1 0.3 2.9 3 0 0 3 3 3 0 Flagellar hook-basal body complex protein FliE Menin PF05053.13 GAM27575.1 - 2.1 6.6 5.3 3.2 6.0 5.3 1.3 1 0 0 1 1 1 0 Menin DHHC PF01529.20 GAM27576.1 - 3e-13 50.0 13.2 3e-13 50.0 13.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DNA_pol_B PF00136.21 GAM27577.1 - 2.4e-117 392.5 0.1 4e-117 391.7 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAM27577.1 - 1e-34 120.2 0.1 1.9e-34 119.4 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 GAM27577.1 - 6.3e-25 88.0 3.1 1.8e-24 86.5 3.1 1.9 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_2 PF03175.13 GAM27577.1 - 0.0052 15.7 0.1 0.0052 15.7 0.1 2.6 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral AAA_21 PF13304.6 GAM27577.1 - 0.0078 16.1 1.0 0.017 14.9 1.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system PADR1 PF08063.12 GAM27577.1 - 7.2 6.5 7.0 14 5.6 2.5 2.7 2 0 0 2 2 2 0 PADR1 (NUC008) domain Rhodanese_C PF12368.8 GAM27577.1 - 9.2 6.7 7.4 3.7 8.0 0.4 2.9 2 1 0 2 2 2 0 Rhodanase C-terminal Rhomboid PF01694.22 GAM27578.1 - 6.2e-38 130.2 13.9 1.2e-37 129.2 13.9 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 GAM27578.1 - 0.07 13.7 0.1 0.07 13.7 0.1 2.6 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) Ribosomal_L6 PF00347.23 GAM27579.1 - 5.8e-25 87.8 6.7 7.5e-16 58.6 1.6 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 ChpA-C PF03777.13 GAM27579.1 - 1.2 9.1 4.5 2 8.4 0.1 2.7 3 0 0 3 3 3 0 ChpA-C Na_H_Exchanger PF00999.21 GAM27580.1 - 4.6e-58 196.8 46.6 6.5e-58 196.3 46.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1672 PF07901.11 GAM27580.1 - 0.04 13.2 0.1 0.073 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) DUF624 PF04854.14 GAM27580.1 - 0.3 11.2 7.6 0.13 12.4 3.0 3.0 2 1 0 2 2 2 0 Protein of unknown function, DUF624 ADK PF00406.22 GAM27581.1 - 4.2e-47 160.0 0.1 5.5e-47 159.6 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAM27581.1 - 5.5e-23 81.9 0.1 1.2e-22 80.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 GAM27581.1 - 1.4e-14 53.8 0.0 4.6e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 GAM27581.1 - 1.5e-07 31.6 0.0 3.1e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM27581.1 - 4.5e-05 24.0 0.1 0.00015 22.3 0.0 1.8 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 GAM27581.1 - 0.00015 21.5 0.9 1.2 8.7 0.0 3.2 2 1 0 3 3 3 2 Thymidylate kinase Zeta_toxin PF06414.12 GAM27581.1 - 0.055 12.7 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin Ploopntkinase3 PF18751.1 GAM27581.1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 6PF2K PF01591.18 GAM27581.1 - 0.2 10.9 1.0 2.3 7.5 0.0 2.6 2 1 1 3 3 3 0 6-phosphofructo-2-kinase Mito_carr PF00153.27 GAM27582.1 - 1.5e-47 159.4 6.7 5.6e-19 67.9 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 GAM27582.1 - 0.053 13.6 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif TPT PF03151.16 GAM27583.1 - 6.1e-13 48.8 20.3 7.7e-13 48.4 20.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Pox_I5 PF04713.12 GAM27583.1 - 0.034 14.2 1.7 0.034 14.2 1.7 3.3 3 1 0 3 3 3 0 Poxvirus protein I5 EF-hand_12 PF17901.1 GAM27584.1 - 1.2e-40 137.9 0.6 5.3e-40 135.8 0.6 2.2 1 0 0 1 1 1 1 EF-hand fold domain STATa_Ig PF18214.1 GAM27584.1 - 4.5e-25 88.0 3.1 4.5e-25 88.0 3.1 1.8 2 0 0 2 2 2 1 STATa Immunoglobulin-like domain SH2 PF00017.24 GAM27584.1 - 5.8e-11 42.3 0.0 1.7e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 GAM27584.1 - 0.02 14.8 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain Lectin_N PF03954.14 GAM27584.1 - 0.21 11.3 2.1 5.4 6.8 0.0 3.0 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain RNA_pol_Rpb4 PF03874.16 GAM27584.1 - 2.5 8.5 9.7 0.2 12.0 3.4 2.4 3 0 0 3 3 3 0 RNA polymerase Rpb4 Dict-STAT-coil PF09267.10 GAM27584.1 - 4.3 7.8 14.7 3.6 8.0 5.3 3.9 3 1 0 3 3 3 0 Dictyostelium STAT, coiled coil GATA PF00320.27 GAM27585.1 - 3e-16 58.7 5.3 7.6e-16 57.4 5.3 1.7 1 0 0 1 1 1 1 GATA zinc finger GFA PF04828.14 GAM27585.1 - 0.23 11.8 3.2 12 6.3 0.9 2.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nod1 PF17114.5 GAM27586.1 - 0.029 14.5 0.1 0.079 13.1 0.1 1.7 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 Sigma70_ner PF04546.13 GAM27586.1 - 0.15 11.9 9.6 0.033 14.1 5.5 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region PPP4R2 PF09184.11 GAM27586.1 - 0.36 10.4 17.5 0.71 9.4 17.5 1.4 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 GAM27586.1 - 1.7 7.9 13.6 3.1 7.0 13.6 1.4 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 GAM27586.1 - 3.1 7.5 16.5 0.16 11.7 11.2 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 GAM27586.1 - 5.7 5.4 16.1 1.8 7.0 13.2 1.4 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.6 GAM27586.1 - 6.5 7.2 17.0 0.65 10.4 11.9 2.0 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myb_DNA-binding PF00249.31 GAM27587.1 - 9.1e-33 112.2 15.0 1.6e-16 60.2 1.5 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM27587.1 - 7.3e-30 103.0 6.1 4e-14 52.6 0.1 3.5 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 GAM27587.1 - 0.00077 19.8 14.6 0.0047 17.3 2.0 3.5 2 1 1 3 3 3 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 GAM27587.1 - 0.0019 18.2 1.9 0.21 11.6 0.0 3.1 3 1 1 4 4 4 1 SLIDE SANT_DAMP1_like PF16282.5 GAM27587.1 - 0.024 14.8 1.0 1.9 8.7 0.0 3.0 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 GAM27587.1 - 0.068 13.5 13.9 1.3 9.4 1.9 4.0 2 2 2 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 GAM27587.1 - 0.22 11.6 9.1 22 5.2 1.5 4.3 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Atg29_N PF18388.1 GAM27587.1 - 0.61 9.9 9.5 0.57 10.0 1.0 3.1 3 0 0 3 3 3 0 Atg29 N-terminal domain Nbl1_Borealin_N PF10444.9 GAM27588.1 - 2.4e-20 71.9 0.9 4.5e-20 71.0 0.9 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DUF421 PF04239.12 GAM27588.1 - 0.25 11.1 3.7 5.2 6.9 3.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF421) MAD PF05557.13 GAM27589.1 - 4.2e-51 174.1 41.8 4.2e-51 174.1 41.8 3.1 1 1 1 2 2 2 1 Mitotic checkpoint protein Med21 PF11221.8 GAM27589.1 - 0.00037 20.8 12.4 0.00037 20.8 12.4 4.4 3 1 1 4 4 4 1 Subunit 21 of Mediator complex DUF4145 PF13643.6 GAM27589.1 - 0.2 11.8 3.4 0.69 10.1 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) Pox_A_type_inc PF04508.12 GAM27589.1 - 0.43 10.5 14.3 6.5 6.8 0.1 5.8 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat PKcGMP_CC PF16808.5 GAM27589.1 - 5.5 6.9 16.5 2.5 8.1 1.0 5.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PG_binding_4 PF12229.8 GAM27590.1 - 0.001 19.4 0.3 0.0028 17.9 0.1 1.8 1 1 1 2 2 2 1 Putative peptidoglycan binding domain NifQ PF04891.12 GAM27591.1 - 0.055 13.8 7.6 0.067 13.5 7.6 1.1 1 0 0 1 1 1 0 NifQ FTZ PF03867.14 GAM27591.1 - 4 6.9 14.0 4.3 6.8 14.0 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region eIF-3_zeta PF05091.12 GAM27591.1 - 8.4 5.2 19.4 9.8 5.0 19.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDK5_activator PF03261.15 GAM27591.1 - 9.5 5.7 21.3 10 5.6 21.3 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein RRM_1 PF00076.22 GAM27594.1 - 4e-14 52.2 0.0 1.9e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 GAM27594.1 - 7.9e-06 25.8 0.0 0.012 15.6 0.0 2.3 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_occluded PF16842.5 GAM27594.1 - 0.015 15.1 0.0 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif dCache_1 PF02743.18 GAM27595.1 - 3.6e-07 30.2 0.9 5e-07 29.8 0.9 1.3 1 0 0 1 1 1 1 Cache domain NHL PF01436.21 GAM27595.1 - 0.00019 21.3 6.2 0.0018 18.2 0.4 4.0 5 0 0 5 5 5 1 NHL repeat Reg_prop PF07494.11 GAM27595.1 - 0.067 13.4 0.4 0.84 10.1 0.4 3.0 2 0 0 2 2 2 0 Two component regulator propeller FH2 PF02181.23 GAM27596.1 - 5.5e-83 279.1 1.7 5.5e-83 279.1 1.7 3.2 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 GAM27596.1 - 6e-35 120.6 0.7 6e-35 120.6 0.7 4.1 4 1 0 4 4 4 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 GAM27596.1 - 1.2e-34 119.5 4.0 1.2e-34 119.5 4.0 3.1 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain C2 PF00168.30 GAM27596.1 - 4e-16 59.2 0.2 1.2e-15 57.7 0.2 1.8 1 0 0 1 1 1 1 C2 domain YhzD PF14120.6 GAM27596.1 - 0.81 9.8 3.0 3 8.0 3.0 2.0 1 0 0 1 1 1 0 YhzD-like protein DUF4865 PF16157.5 GAM27596.1 - 1.8 8.5 5.3 11 5.9 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4865) Glucosamine_iso PF01182.20 GAM27597.1 - 4.7e-42 144.4 0.0 5.7e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Skp1 PF01466.19 GAM27598.1 - 9.1e-22 76.9 0.5 2.6e-21 75.4 0.1 1.9 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GAM27598.1 - 4.1e-20 71.7 0.3 8.4e-20 70.7 0.3 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain TFIID-31kDa PF02291.15 GAM27598.1 - 0.02 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Rab5ip PF07019.12 GAM27599.1 - 3.3e-16 59.6 10.0 4.6e-16 59.2 10.0 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) FA_desaturase PF00487.24 GAM27599.1 - 0.0062 16.4 1.6 0.0069 16.3 1.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase TetR_C_22 PF17928.1 GAM27599.1 - 0.016 15.6 0.1 0.024 15.0 0.1 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SNF2_N PF00176.23 GAM27600.1 - 8.8e-69 231.9 2.3 1.1e-68 231.6 0.8 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM27600.1 - 3.6e-20 72.4 0.0 3.3e-19 69.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.13 GAM27600.1 - 1.2e-12 47.9 0.1 1.2e-12 47.9 0.1 3.7 2 1 0 2 2 2 1 HSA Myb_DNA-binding PF00249.31 GAM27600.1 - 1e-05 25.6 0.0 3e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM27600.1 - 4.6e-05 23.6 0.2 0.00019 21.6 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Connexin PF00029.19 GAM27600.1 - 0.15 11.8 3.4 0.55 10.0 3.4 1.9 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 GAM27601.1 - 1.2e-115 386.5 9.3 1.2e-115 386.5 9.3 1.9 2 0 0 2 2 2 1 Presenilin DUF3377 PF11857.8 GAM27601.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) PhyH PF05721.13 GAM27602.1 - 4.1e-16 59.9 0.1 5.6e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 GAM27602.1 - 0.00022 22.1 0.0 0.00039 21.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ddrB-ParB PF18763.1 GAM27602.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 ddrB-like ParB superfamily domain 2OG-FeII_Oxy_5 PF13759.6 GAM27602.1 - 0.016 15.6 0.1 0.048 14.1 0.0 1.9 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Syntaxin-6_N PF09177.11 GAM27602.1 - 0.054 14.0 0.6 0.15 12.6 0.6 1.8 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SdrD_B PF17210.3 GAM27603.1 - 1.6e-40 137.8 35.2 8.7e-07 29.2 0.3 12.2 12 2 1 13 13 13 10 SdrD B-like domain CarboxypepD_reg PF13620.6 GAM27603.1 - 1.7e-25 89.1 6.4 0.0048 17.1 0.0 10.2 9 1 0 9 9 9 7 Carboxypeptidase regulatory-like domain SpaA PF17802.1 GAM27603.1 - 1.3e-15 57.5 17.4 0.011 16.0 0.1 9.6 9 2 0 9 9 9 5 Prealbumin-like fold domain DUF2012 PF09430.10 GAM27603.1 - 4.5e-09 36.5 0.0 0.57 10.3 0.0 7.2 8 0 0 8 8 8 2 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 GAM27603.1 - 6e-07 29.4 4.0 4.7 7.3 0.0 7.7 8 1 0 8 8 8 3 CarboxypepD_reg-like domain bMG3 PF11974.8 GAM27603.1 - 1.1e-06 28.6 0.0 1.5 8.9 0.0 6.5 6 1 0 6 6 6 1 Bacterial alpha-2-macroglobulin MG3 domain FlgD_ig PF13860.6 GAM27603.1 - 3.8 7.4 16.2 1.3 8.9 0.1 6.4 9 1 1 10 10 10 0 FlgD Ig-like domain SNF2_N PF00176.23 GAM27604.1 - 3.3e-68 230.0 0.0 6.1e-68 229.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM27604.1 - 3.6e-21 75.6 0.0 3.6e-20 72.4 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 GAM27604.1 - 7.1e-07 28.7 0.0 7.1e-07 28.7 0.0 3.7 2 2 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 GAM27604.1 - 0.0027 16.9 0.0 0.0027 16.9 0.0 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Myb_DNA-bind_6 PF13921.6 GAM27605.1 - 7.1e-05 23.0 0.0 0.00027 21.1 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAM27605.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SUIM_assoc PF16619.5 GAM27605.1 - 0.0014 18.6 2.8 0.0014 18.6 2.8 5.8 6 1 0 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 zf-C2H2 PF00096.26 GAM27605.1 - 0.082 13.4 1.4 0.48 11.0 0.2 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type TFIIA PF03153.13 GAM27605.1 - 0.43 10.5 55.0 1.6 8.6 28.0 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF5480 PF17576.2 GAM27606.1 - 0.017 15.1 0.1 0.02 14.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5480) JAB PF01398.21 GAM27607.1 - 3.7e-33 114.0 0.1 6.5e-33 113.2 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 GAM27607.1 - 9.2e-24 84.2 0.2 1.6e-23 83.4 0.2 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 GAM27607.1 - 7.6e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 GAM27607.1 - 0.037 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Glyco_transf_22 PF03901.17 GAM27608.1 - 1.1e-65 222.5 27.5 1.5e-65 222.1 27.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CPP1-like PF11833.8 GAM27608.1 - 0.0047 16.6 0.6 0.0047 16.6 0.6 3.1 2 1 1 3 3 3 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like LAP1C PF05609.12 GAM27608.1 - 0.062 12.4 2.8 0.1 11.6 2.8 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Response_reg PF00072.24 GAM27609.1 - 1.8e-20 73.2 1.1 5.8e-20 71.5 1.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain LRR_6 PF13516.6 GAM27609.1 - 1e-11 43.9 35.4 0.079 13.1 0.1 10.2 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.7 GAM27609.1 - 2.2e-09 37.4 35.3 0.12 12.8 3.4 7.8 5 1 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM27609.1 - 1.6e-07 31.0 32.0 0.00027 20.6 0.1 5.6 4 2 3 7 7 7 4 Leucine rich repeat Hid1 PF12722.7 GAM27609.1 - 0.17 10.0 16.7 0.27 9.3 16.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LRR_1 PF00560.33 GAM27609.1 - 0.38 11.5 25.6 14 6.7 0.0 9.6 10 1 0 10 10 9 0 Leucine Rich Repeat Dicty_REP PF05086.12 GAM27609.1 - 1.5 6.7 18.3 2.8 5.8 18.3 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SOG2 PF10428.9 GAM27609.1 - 1.6 7.8 25.7 0.032 13.4 17.8 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein TFIIA PF03153.13 GAM27609.1 - 1.7 8.5 31.1 0.09 12.8 23.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 GAM27609.1 - 4.1 6.0 20.5 6.2 5.4 20.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mitofilin PF09731.9 GAM27609.1 - 4.4 6.0 17.8 6.4 5.5 17.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF966 PF06136.13 GAM27609.1 - 7.3 6.2 19.4 14 5.3 19.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Cpn60_TCP1 PF00118.24 GAM27610.1 - 1.5e-149 498.8 14.2 1.7e-149 498.6 14.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lipase_3 PF01764.25 GAM27611.1 - 3.9e-20 72.2 0.0 8.6e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Ank_4 PF13637.6 GAM27613.1 - 0.00012 22.6 8.4 0.65 10.6 0.7 7.2 7 2 0 7 7 7 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM27613.1 - 0.091 13.1 2.1 4.6 7.7 0.1 4.5 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Cwf_Cwc_15 PF04889.12 GAM27613.1 - 4.4 7.0 7.6 10 5.7 7.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ank_3 PF13606.6 GAM27613.1 - 6.3 7.7 13.5 2.9e+02 2.6 0.0 8.9 11 0 0 11 11 11 0 Ankyrin repeat FNIP PF05725.12 GAM27616.1 - 0.045 13.9 6.1 11 6.3 0.6 4.4 3 1 0 3 3 3 0 FNIP Repeat Pkinase PF00069.25 GAM27617.1 - 1.1e-42 146.3 0.0 1.3e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27617.1 - 1.5e-20 73.6 0.0 1.8e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM27617.1 - 2.1e-05 24.6 0.1 0.0047 16.9 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 GAM27617.1 - 0.00034 20.0 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAM27617.1 - 0.029 13.1 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 GAM27617.1 - 0.089 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Inj_translocase PF16928.5 GAM27618.1 - 0.022 14.2 1.3 0.022 14.2 1.3 3.5 4 0 0 4 4 4 0 DNA/protein translocase of phage P22 injectosome SRP40_C PF05022.12 GAM27620.1 - 7.9e-16 58.7 1.8 7.9e-16 58.7 1.8 4.1 3 1 0 4 4 4 1 SRP40, C-terminal domain LisH PF08513.11 GAM27620.1 - 0.015 15.3 0.1 0.032 14.2 0.1 1.6 1 0 0 1 1 1 0 LisH Pentapeptide PF00805.22 GAM27621.1 - 1e-43 146.5 39.5 8.2e-14 50.9 4.9 4.4 2 2 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 GAM27621.1 - 8e-31 106.1 17.3 3.1e-13 49.7 1.0 3.0 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 GAM27621.1 - 4e-20 71.7 8.0 4.7e-08 33.1 4.7 4.9 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 GAM27621.1 - 5e-18 65.3 0.0 9e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain KHA PF11834.8 GAM27621.1 - 2.1e-13 50.2 0.0 3.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel BTB_3 PF16017.5 GAM27621.1 - 7.8e-05 22.7 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAM27621.1 - 0.00093 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DCX PF03607.17 GAM27621.1 - 0.036 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Doublecortin NAD_binding_8 PF13450.6 GAM27621.1 - 0.044 14.0 0.1 5.3 7.3 0.0 3.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Acyltransferase PF01553.21 GAM27622.1 - 1.4e-17 63.6 0.0 2.1e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 GAM27622.1 - 0.084 11.8 0.0 0.22 10.4 0.0 1.7 1 1 0 1 1 1 0 Diacylglycerol acyltransferase SRP_TPR_like PF17004.5 GAM27623.1 - 2.4e-14 53.4 4.8 2.4e-14 53.4 4.8 4.1 2 2 2 4 4 4 1 Putative TPR-like repeat TPR_19 PF14559.6 GAM27623.1 - 5.9e-14 52.3 24.3 0.0018 18.7 0.6 7.8 6 2 1 8 8 8 5 Tetratricopeptide repeat SRP72 PF08492.12 GAM27623.1 - 4.6e-11 43.0 11.5 3.7e-10 40.1 11.5 2.7 1 1 0 1 1 1 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 GAM27623.1 - 3.6e-09 36.7 38.2 1.2e-06 28.6 2.7 6.7 3 2 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAM27623.1 - 1.4e-08 34.2 28.6 0.23 11.7 0.0 9.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM27623.1 - 1.9e-07 30.6 27.4 0.11 12.4 0.2 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAM27623.1 - 4e-07 30.3 11.1 0.11 13.2 0.1 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM27623.1 - 8.8e-07 29.2 1.9 8 7.6 0.0 7.3 7 2 1 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM27623.1 - 8.8e-05 22.3 7.3 5.8 7.2 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAM27623.1 - 0.0099 16.0 0.0 9.9 6.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Herpes_heli_pri PF05774.11 GAM27623.1 - 0.057 13.6 0.4 0.17 12.1 0.4 1.8 1 0 0 1 1 1 0 Herpesvirus helicase-primase complex component FrhB_FdhB_N PF04422.13 GAM27623.1 - 0.11 12.6 0.1 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term TPR_12 PF13424.6 GAM27623.1 - 0.26 11.6 25.8 0.37 11.1 0.2 8.1 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM27623.1 - 1.2 9.6 36.8 3.2 8.2 0.1 9.2 9 1 1 10 10 10 0 Tetratricopeptide repeat DUF4810 PF16068.5 GAM27623.1 - 2.2 8.9 0.0 2.2 8.9 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4810) COMM_domain PF07258.14 GAM27624.1 - 9.9e-20 70.4 0.1 1.2e-19 70.1 0.1 1.1 1 0 0 1 1 1 1 COMM domain A_thal_3526 PF09713.10 GAM27625.1 - 1.3e-20 73.4 3.6 2.3e-20 72.6 3.6 1.5 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) DUF226 PF02890.14 GAM27625.1 - 0.075 13.1 1.3 0.12 12.4 1.3 1.3 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 TMEM151 PF14857.6 GAM27625.1 - 1.6 7.6 7.3 5.8 5.7 7.3 1.9 1 1 0 1 1 1 0 TMEM151 family DNA_alkylation PF08713.11 GAM27626.1 - 2.5e-56 190.8 0.3 3.7e-56 190.2 0.3 1.2 1 0 0 1 1 1 1 DNA alkylation repair enzyme Ndc1_Nup PF09531.10 GAM27626.1 - 0.0014 17.4 0.5 0.0014 17.4 0.5 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup NAM-associated PF14303.6 GAM27626.1 - 0.0087 16.8 12.0 0.019 15.7 12.0 1.5 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain MRI PF15325.6 GAM27626.1 - 0.067 14.3 8.1 0.17 13.0 8.1 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection SR-25 PF10500.9 GAM27626.1 - 0.2 11.3 18.3 0.31 10.6 18.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF913 PF06025.12 GAM27626.1 - 4.2 6.2 8.9 5.9 5.8 8.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GAM27626.1 - 6 5.5 5.9 7.1 5.3 5.9 1.1 1 0 0 1 1 1 0 Presenilin Voltage_CLC PF00654.20 GAM27628.1 - 4.4e-92 309.0 25.3 4.4e-92 309.0 25.3 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 GAM27628.1 - 1.5e-11 44.6 0.0 2.4e-05 24.7 0.0 3.3 3 0 0 3 3 3 2 CBS domain SRP40_C PF05022.12 GAM27628.1 - 0.048 14.5 0.0 0.13 13.2 0.0 1.7 1 0 0 1 1 1 0 SRP40, C-terminal domain UCR_Fe-S_N PF10399.9 GAM27628.1 - 0.091 12.1 0.4 0.34 10.3 0.4 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF373 PF04123.13 GAM27628.1 - 3.9 6.8 13.1 0.21 11.0 6.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF373) PKD_channel PF08016.12 GAM27629.1 - 3.1e-35 121.7 26.8 1.7e-20 73.2 16.2 2.5 2 1 1 3 3 3 2 Polycystin cation channel Ion_trans PF00520.31 GAM27629.1 - 0.00026 20.3 22.0 0.00026 20.3 22.0 2.1 3 0 0 3 3 3 1 Ion transport protein Nop25 PF09805.9 GAM27629.1 - 0.0058 17.1 1.6 0.0095 16.4 1.6 1.3 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) CSRNP_N PF16019.5 GAM27629.1 - 0.093 12.6 1.0 0.2 11.5 1.0 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus PAH PF02671.21 GAM27629.1 - 0.25 11.5 2.8 0.48 10.6 0.1 2.7 2 0 0 2 2 2 0 Paired amphipathic helix repeat FUSC PF04632.12 GAM27629.1 - 0.29 9.6 10.5 0.45 9.0 10.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LON_substr_bdg PF02190.16 GAM27629.1 - 0.7 9.7 6.6 0.11 12.4 0.8 2.4 3 0 0 3 3 3 0 ATP-dependent protease La (LON) substrate-binding domain Fmp27_SW PF10305.9 GAM27629.1 - 1.2 9.9 4.7 5.9 7.7 2.2 2.8 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain VPS9 PF02204.18 GAM27630.1 - 4.4e-26 91.1 1.9 1.9e-25 89.1 1.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 GAM27630.1 - 8.7e-05 22.8 0.6 0.0005 20.3 0.6 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Ribosomal_S15 PF00312.22 GAM27631.1 - 1.3e-25 89.4 3.3 3.1e-25 88.2 3.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 Mvb12 PF09452.10 GAM27631.1 - 0.17 12.4 1.2 10 6.6 0.0 3.5 2 1 1 3 3 3 0 ESCRT-I subunit Mvb12 Ribophorin_II PF05817.14 GAM27632.1 - 5.4e-104 349.0 8.1 6.4e-104 348.8 8.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF4487 PF14868.6 GAM27632.1 - 0.0068 15.3 0.1 0.01 14.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4487) HA2 PF04408.23 GAM27633.1 - 4.5e-26 91.2 0.0 4.5e-26 91.2 0.0 3.6 4 1 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAM27633.1 - 3.3e-16 59.4 0.0 9.4e-16 58.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAM27633.1 - 1.8e-09 37.9 0.0 5.2e-08 33.2 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM27633.1 - 1.5e-06 28.1 0.0 4.6e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAM27633.1 - 0.00025 21.3 0.0 0.00067 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 GAM27633.1 - 0.017 14.6 0.1 0.072 12.5 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 GAM27633.1 - 0.49 10.9 0.0 0.49 10.9 0.0 3.3 3 1 0 3 3 3 0 ABC transporter WD40 PF00400.32 GAM27634.1 - 1.7e-23 82.5 3.7 8.8e-06 26.4 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM27634.1 - 7.9e-17 61.3 0.1 0.0028 17.9 0.0 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 GAM27634.1 - 0.00025 19.5 0.0 0.0084 14.5 0.0 2.2 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 GAM27634.1 - 0.0034 16.4 0.1 3.3 6.6 0.0 3.0 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAM27634.1 - 0.004 16.5 0.3 1.1 8.5 0.1 2.9 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 GAM27634.1 - 0.051 12.2 0.3 0.48 9.0 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF4282 PF14110.6 GAM27635.1 - 4e-12 46.7 11.5 4.9e-12 46.4 11.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) C1_2 PF03107.16 GAM27636.1 - 1.3e-12 47.8 21.0 4.4e-05 23.7 3.3 3.3 3 0 0 3 3 3 3 C1 domain ZZ PF00569.17 GAM27636.1 - 5.8e-10 38.8 26.6 1.9e-06 27.6 4.2 3.7 4 0 0 4 4 4 2 Zinc finger, ZZ type IMUP PF15761.5 GAM27637.1 - 3.3 8.5 11.7 2.6 8.8 2.3 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein SRP_SPB PF02978.19 GAM27638.1 - 6.4e-09 36.3 0.1 1.9e-08 34.8 0.1 1.8 1 1 0 1 1 1 1 Signal peptide binding domain DUF2072 PF09845.9 GAM27638.1 - 0.054 13.7 0.4 0.054 13.7 0.4 2.0 1 1 1 2 2 2 0 Zn-ribbon containing protein DUF3235 PF11574.8 GAM27638.1 - 1.7 9.6 7.6 35 5.3 3.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3235) ZapB PF06005.12 GAM27639.1 - 0.0029 18.0 30.1 0.02 15.3 2.0 4.2 4 1 0 4 4 3 2 Cell division protein ZapB Spc7 PF08317.11 GAM27639.1 - 0.034 13.0 31.5 0.62 8.9 14.8 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein WEMBL PF05701.11 GAM27639.1 - 0.047 12.4 24.0 0.073 11.8 24.0 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Baculo_PEP_C PF04513.12 GAM27639.1 - 0.056 13.5 6.8 1.2 9.1 0.5 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 GAM27639.1 - 0.098 11.6 25.5 0.14 11.1 20.8 2.4 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.12 GAM27639.1 - 0.15 12.2 30.9 1.6 8.8 22.0 3.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 GAM27639.1 - 0.27 10.5 20.3 0.032 13.6 11.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 GAM27639.1 - 0.49 10.9 35.3 18 5.8 32.3 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 GAM27639.1 - 0.56 9.6 32.2 2.1 7.7 16.5 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 KASH_CCD PF14662.6 GAM27639.1 - 0.87 9.4 29.6 0.34 10.7 2.0 3.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Mst1_SARAH PF11629.8 GAM27639.1 - 0.97 9.6 7.7 0.1 12.7 0.8 2.9 2 1 1 3 3 3 0 C terminal SARAH domain of Mst1 DUF724 PF05266.14 GAM27639.1 - 1.1 9.1 26.0 3.3 7.5 12.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Laminin_II PF06009.12 GAM27639.1 - 1.2 9.1 17.1 2.1 8.4 8.9 2.8 2 1 1 3 3 2 0 Laminin Domain II DLP_helical PF18709.1 GAM27639.1 - 1.5 7.9 15.6 1.2 8.3 7.0 2.3 1 1 1 2 2 2 0 Dynamin-like helical domain Halo_GVPC PF05465.13 GAM27639.1 - 1.7 9.0 3.3 44 4.5 0.1 3.1 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat GAS PF13851.6 GAM27639.1 - 1.9 7.8 30.4 4.7 6.5 21.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ApoO PF09769.9 GAM27639.1 - 2.7 8.0 5.6 6.1 6.8 2.2 2.9 1 1 1 2 2 2 0 Apolipoprotein O OmpH PF03938.14 GAM27639.1 - 3.1 8.1 32.9 1 9.7 14.2 3.2 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) H-kinase_dim PF02895.14 GAM27639.1 - 3.5 8.1 10.3 16 6.0 0.8 3.4 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF3450 PF11932.8 GAM27639.1 - 4.9 6.4 25.5 0.68 9.2 14.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) YabA PF06156.13 GAM27639.1 - 4.9 7.8 23.7 4e+02 1.7 8.6 3.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF2203 PF09969.9 GAM27639.1 - 5.5 7.7 17.6 20 5.9 0.2 3.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) UPF0242 PF06785.11 GAM27639.1 - 5.9 6.9 32.0 25 4.9 16.1 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ALMT PF11744.8 GAM27639.1 - 6 5.6 15.3 11 4.7 15.3 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter CENP-H PF05837.12 GAM27639.1 - 7.4 7.0 27.1 1.8 9.0 5.9 3.6 1 1 1 2 2 1 0 Centromere protein H (CENP-H) DUF3584 PF12128.8 GAM27639.1 - 9.2 3.6 27.8 17 2.7 27.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) AAA PF00004.29 GAM27641.1 - 1.9e-38 131.9 0.0 9.6e-38 129.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 GAM27641.1 - 4.9e-10 39.3 1.2 1.4e-09 37.9 1.2 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 GAM27641.1 - 1.1e-08 35.0 0.0 8.7e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 GAM27641.1 - 4.1e-06 26.5 0.0 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 GAM27641.1 - 6e-05 22.8 0.0 0.00014 21.6 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAM27641.1 - 0.00043 20.4 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAM27641.1 - 0.00051 20.3 0.3 0.043 14.1 0.3 3.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAM27641.1 - 0.0007 19.6 0.2 0.0091 16.0 0.1 2.8 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GAM27641.1 - 0.0015 17.8 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Bac_DnaA PF00308.18 GAM27641.1 - 0.0071 16.2 0.1 0.053 13.3 0.0 2.2 2 1 0 2 2 2 1 Bacterial dnaA protein DUF4368 PF14287.6 GAM27641.1 - 0.0072 16.6 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4368) Mg_chelatase PF01078.21 GAM27641.1 - 0.009 15.4 0.1 0.02 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GAM27641.1 - 0.011 15.8 0.0 0.062 13.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF2076 PF09849.9 GAM27641.1 - 0.012 15.7 4.5 0.012 15.7 4.5 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TniB PF05621.11 GAM27641.1 - 0.014 14.8 0.0 0.34 10.3 0.0 2.7 2 1 1 3 3 3 0 Bacterial TniB protein DUF3387 PF11867.8 GAM27641.1 - 0.02 14.3 0.1 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3387) IstB_IS21 PF01695.17 GAM27641.1 - 0.03 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Guanylate_kin PF00625.21 GAM27641.1 - 0.044 13.5 0.0 0.78 9.4 0.0 2.6 2 1 0 2 2 2 0 Guanylate kinase AAA_16 PF13191.6 GAM27641.1 - 0.13 12.7 0.1 0.48 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain SdrD_B PF17210.3 GAM27642.1 - 1.3e-40 138.1 135.8 2.1e-08 34.4 0.2 15.3 10 2 5 15 15 15 10 SdrD B-like domain DUF2012 PF09430.10 GAM27642.1 - 5.5e-11 42.7 0.0 1.9 8.6 0.0 8.6 9 0 0 9 9 9 3 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 GAM27642.1 - 1.9e-07 31.3 0.2 9.5e-05 22.6 0.1 16.0 11 1 3 15 15 15 6 Carboxypeptidase regulatory-like domain SpaA PF17802.1 GAM27642.1 - 0.0017 18.6 0.1 0.0017 18.6 0.1 15.7 12 1 0 12 12 12 7 Prealbumin-like fold domain Dioxygenase_C PF00775.21 GAM27642.1 - 0.0079 15.6 0.1 7.8 5.9 0.0 3.7 4 0 0 4 4 4 1 Dioxygenase DUF3463 PF11946.8 GAM27642.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) LELP1 PF15042.6 GAM27642.1 - 0.41 11.0 5.4 2 8.8 5.4 2.2 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Mito_carr PF00153.27 GAM27643.1 - 1.9e-59 197.6 7.2 1.3e-19 69.9 0.0 3.7 3 1 1 4 4 4 3 Mitochondrial carrier protein TFIIA PF03153.13 GAM27643.1 - 0.15 12.1 8.8 0.2 11.6 8.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 GAM27643.1 - 4.3 6.3 6.9 6.4 5.8 6.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 GAM27643.1 - 5.5 6.5 14.5 8.7 5.9 14.5 1.2 1 0 0 1 1 1 0 Spt20 family DUF1741 PF08427.10 GAM27644.1 - 1.7e-61 207.9 1.6 2.4e-61 207.4 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Bundlin PF05307.11 GAM27644.1 - 0.015 15.1 0.2 0.044 13.6 0.2 1.8 1 0 0 1 1 1 0 Bundlin Suf PF05843.14 GAM27644.1 - 0.14 12.1 7.2 0.27 11.2 7.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4407 PF14362.6 GAM27644.1 - 0.16 11.3 0.7 0.22 10.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.9 GAM27644.1 - 1.2 7.3 10.6 1.7 6.8 10.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BRF1 PF07741.13 GAM27644.1 - 2.7 8.4 6.1 6.9 7.1 6.1 1.7 1 1 0 1 1 1 0 Brf1-like TBP-binding domain CCDC53 PF10152.9 GAM27644.1 - 9.8 6.6 11.8 7.7 6.9 9.9 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ank_2 PF12796.7 GAM27645.1 - 1.3e-09 38.5 0.1 0.0038 17.8 0.0 3.7 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM27645.1 - 1.2e-06 29.0 0.1 0.03 14.9 0.0 4.6 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM27645.1 - 0.0012 19.1 0.0 3.4 8.1 0.0 4.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM27645.1 - 0.0036 17.7 0.2 99 4.0 0.0 5.0 5 0 0 5 5 5 0 Ankyrin repeat DUF3447 PF11929.8 GAM27645.1 - 0.007 16.3 0.5 1.8 8.6 0.0 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Nif11 PF07862.11 GAM27645.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 Nif11 domain AAA_22 PF13401.6 GAM27647.1 - 0.0014 18.9 0.0 0.0045 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain TAD2 PF18521.1 GAM27647.1 - 1.1 9.4 3.1 11 6.3 0.3 2.7 2 0 0 2 2 2 0 Transactivation domain 2 FNIP PF05725.12 GAM27648.1 - 1.1e-90 297.6 42.0 1.1e-15 57.5 0.6 8.6 7 1 0 8 8 8 8 FNIP Repeat DUF1769 PF08588.10 GAM27648.1 - 2.1e-05 24.6 3.2 3.1 8.1 0.0 5.4 7 0 0 7 7 7 3 Protein of unknown function (DUF1769) CH PF00307.31 GAM27649.1 - 2.6e-33 114.4 6.5 1e-08 35.3 0.0 5.8 5 1 0 5 5 5 5 Calponin homology (CH) domain PH PF00169.29 GAM27649.1 - 1.8e-12 47.7 0.3 5e-12 46.3 0.3 1.8 1 0 0 1 1 1 1 PH domain FERM_f0 PF16511.5 GAM27649.1 - 2.2e-11 43.9 0.2 6.5e-10 39.2 0.0 2.7 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM CAMSAP_CH PF11971.8 GAM27649.1 - 0.00011 22.0 0.2 0.19 11.6 0.0 3.5 3 0 0 3 3 3 1 CAMSAP CH domain FERM_N PF09379.10 GAM27649.1 - 0.0002 21.2 0.1 0.58 10.1 0.0 2.8 2 0 0 2 2 2 2 FERM N-terminal domain CH_2 PF06294.11 GAM27649.1 - 0.0013 18.8 0.6 0.031 14.4 0.0 3.5 4 0 0 4 4 4 1 CH-like domain in sperm protein DUF960 PF06124.11 GAM27649.1 - 0.055 14.1 0.1 0.19 12.4 0.1 1.8 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) Exonuc_VII_L PF02601.15 GAM27649.1 - 0.71 9.4 12.1 1.9 8.0 12.1 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 GAM27649.1 - 4.5 5.1 7.9 7.9 4.2 7.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_transf_5 PF08323.11 GAM27650.1 - 2e-34 119.4 0.0 3.8e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 GAM27650.1 - 3.9e-13 49.3 0.0 1.6e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAM27650.1 - 2.2e-08 34.6 0.0 7.4e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.24 GAM27650.1 - 0.002 17.8 0.2 0.3 10.6 0.0 2.5 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_4 PF13439.6 GAM27650.1 - 0.0074 16.3 0.3 0.027 14.5 0.3 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAM27650.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF4411 PF14367.6 GAM27650.1 - 0.19 11.7 0.1 0.41 10.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Notch PF00066.17 GAM27651.1 - 1.5e-55 185.3 135.2 2.3e-08 34.3 11.3 9.1 9 0 0 9 9 9 8 LNR domain Adap_comp_sub PF00928.21 GAM27654.1 - 2.2e-90 302.6 0.2 2.9e-90 302.2 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAM27654.1 - 2.7e-10 40.4 0.5 4.5e-10 39.6 0.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DDHD PF02862.17 GAM27655.1 - 1.4e-34 120.2 0.1 7.6e-34 117.8 0.1 1.9 2 0 0 2 2 2 1 DDHD domain DUF676 PF05057.14 GAM27655.1 - 0.17 11.4 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) WD40 PF00400.32 GAM27656.1 - 1.7e-36 123.6 23.4 2e-05 25.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM27656.1 - 4.3e-11 43.0 0.0 0.18 12.1 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM27656.1 - 0.00014 21.3 0.0 0.00041 19.8 0.0 2.1 1 1 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 GAM27656.1 - 0.041 12.5 0.1 6.4 5.3 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 CRF PF00473.17 GAM27656.1 - 0.63 10.2 2.0 1.2 9.3 2.0 1.3 1 0 0 1 1 1 0 Corticotropin-releasing factor family HhH-GPD PF00730.25 GAM27657.1 - 1.2e-20 74.0 0.0 2.1e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAM27657.1 - 0.00014 21.5 0.0 0.0004 20.1 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 GAM27657.1 - 0.061 13.7 5.4 0.1 13.0 5.4 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III CDK2AP PF09806.9 GAM27657.1 - 0.52 10.3 10.9 0.055 13.5 5.2 2.1 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein PBP1_TM PF14812.6 GAM27657.1 - 2 8.8 12.6 2.4 8.6 8.4 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FSA_C PF10479.9 GAM27657.1 - 3 5.9 9.0 4.5 5.3 9.0 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus CAML PF14963.6 GAM27657.1 - 5.2 7.1 8.0 0.18 11.9 1.0 1.9 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand BSP_II PF05432.11 GAM27657.1 - 6.3 6.4 24.4 0.29 10.8 8.0 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) RRM_1 PF00076.22 GAM27658.1 - 1.3e-19 69.7 0.1 1.9e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM27658.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAM27658.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif Limkain-b1 PF11608.8 GAM27658.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 Sod_Fe_C PF02777.18 GAM27659.1 - 4e-28 97.6 0.5 7.2e-28 96.7 0.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAM27659.1 - 1.7e-10 41.2 0.1 1.7e-10 41.2 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain TetR_C_10 PF16295.5 GAM27659.1 - 0.07 13.4 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain EMP70 PF02990.16 GAM27660.1 - 2.5e-155 518.1 19.8 2.5e-155 518.1 19.8 1.9 3 0 0 3 3 3 1 Endomembrane protein 70 PALP PF00291.25 GAM27661.1 - 1.8e-82 277.1 0.0 2.6e-75 253.6 0.1 2.8 2 1 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme ACT_5 PF13710.6 GAM27661.1 - 0.0099 15.7 0.3 0.026 14.4 0.3 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 GAM27661.1 - 0.022 15.4 0.3 0.17 12.5 0.1 2.5 2 0 0 2 2 2 0 ACT domain DUF2465 PF10239.9 GAM27663.1 - 7.7e-39 133.8 2.5 1e-38 133.4 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) Pro_3_hydrox_C PF05373.11 GAM27663.1 - 0.057 13.5 0.2 0.25 11.4 0.1 2.0 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal Nexin_C PF08628.12 GAM27663.1 - 0.084 13.4 0.3 0.28 11.8 0.3 2.0 1 0 0 1 1 1 0 Sorting nexin C terminal DUF2106 PF09879.9 GAM27664.1 - 0.052 13.1 0.4 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2106) DUF3021 PF11457.8 GAM27664.1 - 0.085 13.2 5.9 0.17 12.3 5.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) AT_hook PF02178.19 GAM27665.1 - 0.011 15.5 3.7 0.025 14.4 3.7 1.6 1 0 0 1 1 1 0 AT hook motif Ank_2 PF12796.7 GAM27666.1 - 3.1e-30 104.6 0.4 9.1e-16 58.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM27666.1 - 1.3e-24 86.2 0.2 1e-13 51.5 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM27666.1 - 1.6e-17 61.8 0.7 4.1e-05 23.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 GAM27666.1 - 4.7e-17 61.8 2.2 1.1e-08 35.2 0.1 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM27666.1 - 8.9e-16 57.5 0.2 0.00029 21.1 0.2 3.5 3 0 0 3 3 3 3 Ankyrin repeat DUF1843 PF08898.10 GAM27666.1 - 0.11 13.0 0.0 18 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Hydrolase_4 PF12146.8 GAM27667.1 - 2.9e-17 62.7 0.0 7.9e-10 38.4 0.0 2.8 1 1 2 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAM27667.1 - 5.6e-17 62.2 0.0 7.4e-10 38.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 GAM27667.1 - 7e-08 32.6 0.0 0.00049 20.1 0.0 2.8 2 1 1 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 GAM27667.1 - 2e-07 30.7 0.0 4.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 GAM27667.1 - 4e-06 26.5 0.0 1.3e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 GAM27667.1 - 7.3e-05 23.5 0.0 0.037 14.6 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DUF818 PF05677.12 GAM27667.1 - 0.00032 19.8 0.0 0.00048 19.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 GAM27667.1 - 0.00052 19.9 0.0 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 GAM27667.1 - 0.0017 17.1 0.1 0.0047 15.6 0.0 1.7 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 GAM27667.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 GAM27667.1 - 0.0041 17.0 0.0 0.02 14.7 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 GAM27667.1 - 0.093 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1057 PF06342.12 GAM27667.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.25 GAM27667.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S10 PF00450.22 GAM27668.1 - 7.8e-120 401.1 6.4 9.6e-120 400.8 6.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_35 PF01301.19 GAM27669.1 - 5e-104 348.3 0.1 7.3e-104 347.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 GAM27669.1 - 7.3e-15 55.2 0.2 3e-13 49.9 0.2 2.2 1 1 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 GAM27669.1 - 0.00039 19.9 0.0 0.00084 18.8 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BetaGal_dom4_5 PF13364.6 GAM27669.1 - 0.0021 18.6 3.8 0.003 18.1 0.6 2.5 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain RRM_1 PF00076.22 GAM27670.1 - 3.3e-18 65.3 0.2 4.5e-18 64.8 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAM27670.1 - 0.039 14.0 0.1 0.061 13.4 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif AIF-MLS PF14962.6 GAM27672.1 - 0.44 10.5 10.4 0.47 10.4 10.4 1.0 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Nucleoporin_FG PF13634.6 GAM27673.1 - 2.5e-14 53.9 111.9 5.2e-08 33.6 33.4 6.8 2 2 4 6 6 6 5 Nucleoporin FG repeat region DUF3519 PF12033.8 GAM27673.1 - 0.05 14.0 1.7 1.1 9.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) ATG16 PF08614.11 GAM27673.1 - 0.65 10.2 2.0 0.52 10.5 0.3 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) RPW8 PF05659.11 GAM27673.1 - 1.2 8.8 3.2 9.4 5.9 0.3 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Snapin_Pallidin PF14712.6 GAM27673.1 - 3.7 8.0 4.9 2.4 8.6 1.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin FNIP PF05725.12 GAM27674.1 - 5.1e-53 177.0 27.9 1.3e-08 34.9 0.1 10.1 7 2 2 9 9 9 9 FNIP Repeat DUF1769 PF08588.10 GAM27674.1 - 0.0077 16.4 1.5 1.7 8.9 0.0 4.3 4 1 1 5 5 5 1 Protein of unknown function (DUF1769) FNIP PF05725.12 GAM27675.1 - 5.7e-114 372.1 52.1 3.2e-13 49.6 0.7 16.1 10 4 6 18 18 18 16 FNIP Repeat Spc29 PF17082.5 GAM27676.1 - 0.0089 15.9 0.7 0.015 15.2 0.7 1.6 1 1 0 1 1 1 1 Spindle Pole Component 29 DUF1465 PF07323.12 GAM27676.1 - 0.049 13.5 0.2 0.072 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) PspA_IM30 PF04012.12 GAM27676.1 - 0.081 12.5 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 PspA/IM30 family FNIP PF05725.12 GAM27677.1 - 2.9e-61 203.4 15.1 2.7e-12 46.6 0.1 7.7 7 0 0 7 7 7 6 FNIP Repeat Csm1_N PF18504.1 GAM27677.1 - 0.00034 20.9 0.5 0.00057 20.2 0.5 1.3 1 0 0 1 1 1 1 Csm1 N-terminal domain LRS4 PF10422.9 GAM27677.1 - 0.086 12.4 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TolA_bind_tri PF16331.5 GAM27677.1 - 0.17 12.0 1.9 0.33 11.1 1.9 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Mucin PF01456.17 GAM27678.1 - 0.24 11.4 7.9 0.36 10.8 7.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SPATA24 PF15175.6 GAM27680.1 - 0.55 10.1 7.1 0.27 11.1 1.2 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 PAP_assoc PF03828.19 GAM27681.1 - 1.2e-18 67.1 0.3 3e-18 65.8 0.3 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAM27681.1 - 1.5e-06 28.4 0.0 3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAM27681.1 - 0.0079 16.3 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase TPR_19 PF14559.6 GAM27682.1 - 3.3e-15 56.4 8.6 0.021 15.3 0.0 6.3 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 GAM27682.1 - 2.8e-12 46.3 20.1 0.034 15.0 0.2 9.1 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAM27682.1 - 2.9e-05 24.1 0.8 0.12 12.8 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAM27682.1 - 3.8e-05 24.3 7.4 0.055 14.1 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat PknG_TPR PF16918.5 GAM27682.1 - 0.00071 18.4 1.0 0.64 8.7 0.4 2.4 2 0 0 2 2 2 2 Protein kinase G tetratricopeptide repeat TPR_8 PF13181.6 GAM27682.1 - 0.033 14.4 15.4 61 4.2 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAM27682.1 - 0.095 12.7 1.1 6.3 6.8 0.2 3.7 3 1 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 GAM27682.1 - 0.35 11.1 19.5 13 6.2 0.1 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 GAM27683.1 - 7e-51 173.2 1.1 8.3e-51 173.0 1.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM27683.1 - 1.5e-20 73.6 0.6 7.3e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM27683.1 - 9.8e-18 64.5 1.5 1.8e-16 60.5 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAM27683.1 - 0.00037 19.8 0.1 0.81 8.8 0.0 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 GAM27683.1 - 0.00055 19.2 1.2 0.0028 16.9 0.1 2.3 2 1 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 GAM27683.1 - 0.00099 18.6 0.9 0.015 14.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 GAM27683.1 - 0.0059 17.0 0.3 0.022 15.2 0.0 2.1 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 GAM27683.1 - 0.027 13.2 0.5 0.27 9.9 0.4 2.3 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 GAM27683.1 - 0.032 14.5 0.5 0.21 11.8 0.2 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAM27683.1 - 0.035 13.2 4.8 0.59 9.1 1.5 2.7 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.22 GAM27683.1 - 0.12 11.4 10.9 0.55 9.2 0.8 3.6 2 2 2 4 4 4 0 Glucose inhibited division protein A KH_8 PF17903.1 GAM27684.1 - 2.4e-26 91.6 0.0 5.4e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 GAM27684.1 - 0.073 12.9 0.0 0.35 10.7 0.0 2.2 1 1 1 2 2 2 0 KH domain Prefoldin PF02996.17 GAM27685.1 - 1.3e-24 86.4 2.6 1.3e-24 86.4 2.6 1.6 2 1 0 2 2 2 1 Prefoldin subunit CTK3 PF12243.8 GAM27685.1 - 0.012 15.6 0.9 0.024 14.6 0.9 1.6 1 1 0 1 1 1 0 CTD kinase subunit gamma CTK3 AIP3 PF03915.13 GAM27685.1 - 0.03 13.4 11.8 0.033 13.3 11.8 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 HsbA PF12296.8 GAM27685.1 - 0.04 14.3 5.3 8.8 6.8 4.0 2.4 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Anth_Ig PF05587.13 GAM27685.1 - 0.065 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Anthrax receptor extracellular domain TOM20_plant PF06552.12 GAM27685.1 - 0.067 12.9 1.6 0.074 12.8 0.2 1.7 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Nup88 PF10168.9 GAM27685.1 - 0.43 8.3 12.1 0.61 7.8 12.1 1.2 1 0 0 1 1 1 0 Nuclear pore component TLV_coat PF00429.19 GAM27685.1 - 0.57 8.8 9.0 0.71 8.5 0.7 2.1 2 0 0 2 2 2 0 ENV polyprotein (coat polyprotein) SUIM_assoc PF16619.5 GAM27685.1 - 5.9 7.0 12.0 70 3.6 12.0 2.7 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MIP PF00230.20 GAM27686.1 - 1.7e-49 168.6 14.7 2e-49 168.3 14.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein CBS PF00571.28 GAM27687.1 - 2.7e-16 59.7 3.2 0.00017 21.9 0.1 4.7 4 1 0 4 4 4 4 CBS domain FNIP PF05725.12 GAM27688.1 - 2.3e-53 178.1 32.6 9e-15 54.6 1.4 10.2 6 4 3 9 9 9 8 FNIP Repeat FMO-like PF00743.19 GAM27689.1 - 3.2e-49 167.8 0.0 4.9e-49 167.1 0.0 1.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAM27689.1 - 5.2e-21 75.2 0.1 8.5e-18 64.6 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM27689.1 - 2.3e-18 66.4 0.0 1.8e-14 53.7 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAM27689.1 - 1.1e-11 45.1 0.4 2e-06 28.2 0.2 4.0 4 1 1 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM27689.1 - 2.3e-11 43.9 0.0 0.017 14.7 1.4 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAM27689.1 - 2.6e-11 43.6 0.1 2.6e-06 27.5 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAM27689.1 - 1.1e-09 38.0 0.1 3.1e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAM27689.1 - 2.7e-09 37.2 0.1 0.0017 18.4 0.0 3.8 2 2 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 GAM27689.1 - 5.5e-07 29.0 0.2 0.0024 17.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 GAM27689.1 - 6.5e-07 29.0 0.0 6.5e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 GAM27689.1 - 4e-06 26.2 0.9 0.0017 17.5 0.4 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 GAM27689.1 - 7.8e-06 24.8 0.7 0.0069 15.1 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 GAM27689.1 - 1e-05 24.9 0.3 0.053 12.8 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 GAM27689.1 - 7.5e-05 22.1 0.3 0.0058 15.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 GAM27689.1 - 8.4e-05 22.5 0.1 0.00064 19.6 0.0 2.3 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAM27689.1 - 0.00045 20.3 0.0 0.00081 19.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 GAM27689.1 - 0.00089 19.8 0.1 0.017 15.7 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 GAM27689.1 - 0.0022 17.6 0.0 0.0056 16.3 0.0 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 GAM27689.1 - 0.0037 16.9 0.1 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 GAM27689.1 - 0.0056 16.7 0.1 0.028 14.4 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 GAM27689.1 - 0.0075 15.4 0.2 1.2 8.1 0.1 2.9 2 1 1 3 3 3 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 GAM27689.1 - 0.0091 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAM27689.1 - 0.011 15.3 1.7 0.035 13.7 1.0 2.1 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 GAM27689.1 - 0.012 16.1 0.1 0.03 14.8 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 GAM27689.1 - 0.026 13.8 0.1 5.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 GAM27689.1 - 0.039 14.2 0.0 0.095 13.0 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_trans_4_4 PF13579.6 GAM27689.1 - 0.045 14.2 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain TrkA_N PF02254.18 GAM27689.1 - 0.053 13.8 0.1 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_2 PF03446.15 GAM27689.1 - 0.053 13.7 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 GAM27689.1 - 0.1 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Amino_oxidase PF01593.24 GAM27689.1 - 0.16 11.3 0.0 6.9 5.8 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase PLAC8 PF04749.17 GAM27690.1 - 4.3e-12 46.9 21.3 5.4e-12 46.6 21.3 1.2 1 0 0 1 1 1 1 PLAC8 family Cyt-b5 PF00173.28 GAM27691.1 - 2.8e-05 24.2 0.2 7.4e-05 22.8 0.1 1.8 1 1 1 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain PMC2NT PF08066.12 GAM27691.1 - 0.039 14.7 2.0 0.18 12.5 0.2 2.2 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Pox_RNA_Pol_19 PF05320.12 GAM27691.1 - 0.051 13.5 1.1 0.081 12.9 1.1 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Myosin_head PF00063.21 GAM27692.1 - 1.5e-276 919.0 2.1 2.1e-276 918.6 2.1 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAM27692.1 - 7.6e-40 136.6 3.2 1.4e-39 135.7 3.2 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 GAM27692.1 - 5.4e-09 35.1 6.9 0.00013 21.5 0.6 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif RsgA_GTPase PF03193.16 GAM27692.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Hpr_kinase_C PF07475.12 GAM27692.1 - 0.07 12.6 0.4 5.9 6.4 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.6 GAM27692.1 - 0.1 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAM27692.1 - 0.1 12.9 0.0 1.1 9.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 GAM27692.1 - 0.11 12.8 0.0 0.55 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 GAM27692.1 - 0.13 12.2 0.0 13 5.7 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.6 GAM27692.1 - 0.13 12.5 0.0 0.51 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.26 GAM27693.1 - 1.4e-52 177.1 0.0 1.5e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAM27693.1 - 0.0022 18.2 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 GAM27693.1 - 0.0051 16.5 0.0 0.0063 16.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GAM27693.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain UPF0054 PF02130.17 GAM27694.1 - 0.012 15.5 1.5 0.027 14.3 0.8 1.9 1 1 0 1 1 1 0 Uncharacterized protein family UPF0054 VIT1 PF01988.19 GAM27694.1 - 0.38 10.6 7.4 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 VIT family Phage_Gp19 PF09355.10 GAM27694.1 - 2.3 8.7 7.6 0.16 12.4 2.3 1.8 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 Ank_2 PF12796.7 GAM27695.1 - 6.7e-05 23.4 0.2 0.58 10.8 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM27695.1 - 0.0013 19.0 1.1 21 6.1 0.0 6.2 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 GAM27695.1 - 0.0051 17.4 0.3 66 4.3 0.1 4.8 3 1 1 4 4 4 0 Ankyrin repeats (many copies) BRCT PF00533.26 GAM27696.1 - 1.1e-09 38.6 0.5 2.9e-09 37.2 0.5 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAM27696.1 - 4.5e-09 36.6 0.1 9.5e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 GAM27696.1 - 0.0005 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_3 PF18428.1 GAM27696.1 - 0.0013 18.8 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Gtr1_RagA PF04670.12 GAM27697.1 - 2.9e-70 236.2 3.2 3.9e-70 235.8 3.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM27697.1 - 3.4e-06 27.3 0.0 6.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM27697.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAM27697.1 - 3e-05 23.5 0.1 4.7e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM27697.1 - 0.00034 20.7 0.0 0.0019 18.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 GAM27697.1 - 0.001 18.7 0.2 0.0015 18.2 0.2 1.3 1 0 0 1 1 1 1 Ras family Stirrup PF09061.6 GAM27697.1 - 0.072 13.3 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Stirrup Solute_trans_a PF03619.16 GAM27698.1 - 9.6e-93 310.5 21.1 1.2e-92 310.2 21.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-B_box PF00643.24 GAM27699.1 - 1.3e-05 25.2 3.3 2.9e-05 24.1 3.3 1.6 1 0 0 1 1 1 1 B-box zinc finger DUF4175 PF13779.6 GAM27699.1 - 0.014 13.3 10.0 0.018 13.0 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.13 GAM27699.1 - 0.02 14.9 15.6 0.02 14.9 15.6 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 GAM27699.1 - 0.18 12.8 4.3 0.34 11.9 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 GAM27699.1 - 0.3 9.8 1.2 0.39 9.4 1.2 1.2 1 0 0 1 1 1 0 Presenilin ARS2 PF04959.13 GAM27699.1 - 0.41 11.0 7.1 0.76 10.1 7.1 1.4 1 0 0 1 1 1 0 Arsenite-resistance protein 2 Pex14_N PF04695.13 GAM27699.1 - 0.63 10.7 14.3 1.1 9.9 14.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 GAM27699.1 - 1.1 9.3 21.0 0.14 12.1 14.9 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Mit_KHE1 PF10173.9 GAM27699.1 - 1.3 9.1 10.3 0.42 10.7 7.0 1.7 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related Spt20 PF12090.8 GAM27699.1 - 1.7 8.2 31.8 1.4 8.5 30.0 1.7 2 0 0 2 2 2 0 Spt20 family WASH-7_C PF14746.6 GAM27699.1 - 1.9 8.1 11.3 0.53 9.9 7.9 1.7 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal DUF4407 PF14362.6 GAM27699.1 - 2.5 7.4 5.3 1.5 8.1 2.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) EIIBC-GUT_N PF03612.14 GAM27699.1 - 2.9 7.6 7.4 1.5 8.5 2.8 2.3 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus Kelch_6 PF13964.6 GAM27700.1 - 2.2e-13 49.9 4.6 8.4e-05 22.7 0.0 4.9 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 GAM27700.1 - 2.2e-12 46.4 2.1 3.4e-05 23.3 0.0 5.0 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 GAM27700.1 - 9.6e-10 38.3 12.3 8e-05 22.6 0.2 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM27700.1 - 3.4e-07 30.0 2.6 0.056 13.4 0.1 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 GAM27700.1 - 3.6e-05 23.9 6.5 0.82 10.0 0.2 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM27700.1 - 0.011 15.7 9.8 0.11 12.5 0.1 4.0 4 0 0 4 4 4 0 Kelch motif tRNA-synt_His PF13393.6 GAM27701.1 - 1.7e-37 129.4 0.0 3e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 GAM27701.1 - 1.2e-14 54.6 0.0 2.2e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAM27701.1 - 2.8e-11 43.4 0.1 9.2e-11 41.7 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2d PF01409.20 GAM27701.1 - 0.0013 18.3 0.0 0.0041 16.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) DAGK_cat PF00781.24 GAM27701.1 - 0.088 12.4 0.0 3.4 7.3 0.0 3.1 2 1 0 2 2 2 0 Diacylglycerol kinase catalytic domain CBFD_NFYB_HMF PF00808.23 GAM27702.1 - 3.4e-19 68.9 0.4 5.4e-19 68.2 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM27702.1 - 0.0068 16.8 0.1 0.0068 16.8 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 zf-RING_2 PF13639.6 GAM27703.1 - 9.6e-10 38.6 7.1 1.8e-09 37.8 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAM27703.1 - 3.7e-08 33.5 5.2 1.6e-07 31.5 5.2 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAM27703.1 - 2.1e-07 30.7 4.5 3.5e-07 30.0 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM27703.1 - 9.1e-07 28.7 5.7 1.8e-06 27.7 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM27703.1 - 3.2e-06 27.1 2.3 4.1e-06 26.7 1.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAM27703.1 - 5.7e-06 26.1 6.6 1.4e-05 24.9 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM27703.1 - 2.5e-05 24.1 4.9 4.5e-05 23.2 4.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAM27703.1 - 0.00015 21.7 4.4 0.00036 20.4 4.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GAM27703.1 - 0.00037 20.1 4.7 0.00074 19.1 4.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAM27703.1 - 0.0046 17.0 3.3 0.0046 17.0 3.3 2.3 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2849 PF11011.8 GAM27703.1 - 0.099 13.3 0.0 0.099 13.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) zf-C3HC4_4 PF15227.6 GAM27703.1 - 0.12 12.5 4.5 0.32 11.2 4.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 GAM27703.1 - 0.51 10.7 5.3 1.2 9.6 5.3 1.6 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 GAM27703.1 - 0.94 9.7 6.3 2.3 8.4 6.3 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 GAM27703.1 - 3.2 7.6 4.8 14 5.6 4.8 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 GAM27703.1 - 3.4 7.5 7.7 0.22 11.3 2.3 1.8 2 0 0 2 2 2 0 RING-like zinc finger DUF2054 PF10218.9 GAM27704.1 - 5.5e-27 94.5 17.3 7.6e-26 90.8 17.3 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) Cwf_Cwc_15 PF04889.12 GAM27704.1 - 0.089 12.5 7.0 0.12 12.0 7.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PH PF00169.29 GAM27707.1 - 4.9e-09 36.6 0.1 6.5e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 GAM27707.1 - 0.03 14.4 0.1 0.043 13.9 0.1 1.2 1 0 0 1 1 1 0 PH domain Amidohydro_1 PF01979.20 GAM27708.1 - 1.9e-71 241.2 0.0 2.2e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAM27708.1 - 3.6e-09 36.6 0.0 0.00051 19.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family PIP5K PF01504.18 GAM27709.1 - 7.2e-95 317.3 1.7 2.8e-94 315.4 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Coilin_N PF15862.5 GAM27709.1 - 0.029 14.2 0.1 0.029 14.2 0.1 2.5 2 0 0 2 2 2 0 Coilin N-terminus Atg14 PF10186.9 GAM27709.1 - 2.8 6.9 13.3 0.046 12.8 4.4 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SUIM_assoc PF16619.5 GAM27709.1 - 7 6.8 17.2 0.22 11.6 5.4 3.7 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 LAMTOR PF15454.6 GAM27710.1 - 0.056 14.1 0.9 0.11 13.1 0.1 1.9 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator BTB_2 PF02214.22 GAM27711.1 - 2.5e-21 75.8 0.0 5.3e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 GAM27711.1 - 1.7e-12 47.3 0.0 3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Smg4_UPF3 PF03467.15 GAM27715.1 - 2.3e-21 76.6 5.3 3.2e-21 76.1 5.3 1.1 1 0 0 1 1 1 1 Smg-4/UPF3 family UPF0449 PF15136.6 GAM27715.1 - 0.065 13.7 3.7 0.23 12.0 1.3 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 AAA_23 PF13476.6 GAM27716.1 - 0.0031 18.0 11.6 0.0036 17.8 11.6 1.1 1 0 0 1 1 1 1 AAA domain DUF1741 PF08427.10 GAM27716.1 - 0.011 15.4 1.0 0.011 15.4 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) Viral_Rep PF02407.16 GAM27716.1 - 0.029 14.6 0.3 0.041 14.1 0.3 1.3 1 0 0 1 1 1 0 Putative viral replication protein Uds1 PF15456.6 GAM27716.1 - 0.13 12.5 12.5 0.17 12.0 12.5 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Katanin_con80 PF13925.6 GAM27716.1 - 0.16 12.0 4.7 0.24 11.4 4.7 1.4 1 0 0 1 1 1 0 con80 domain of Katanin Allexi_40kDa PF05549.11 GAM27716.1 - 0.3 10.6 6.5 0.33 10.4 6.5 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein FapA PF03961.13 GAM27716.1 - 0.43 9.1 13.3 0.45 9.1 13.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 GAM27716.1 - 0.43 8.4 9.7 0.45 8.4 9.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WDCP PF15390.6 GAM27716.1 - 0.71 8.2 6.7 0.79 8.0 6.7 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family FAM76 PF16046.5 GAM27716.1 - 0.95 8.8 13.5 1 8.7 13.5 1.0 1 0 0 1 1 1 0 FAM76 protein DUF4407 PF14362.6 GAM27716.1 - 1.2 8.4 7.7 1.4 8.2 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4094 PF13334.6 GAM27716.1 - 2.7 8.5 8.8 3.7 8.0 8.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4140 PF13600.6 GAM27716.1 - 3.8 8.0 12.2 20 5.7 12.2 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 GAM27716.1 - 5.6 5.9 15.2 6.1 5.8 15.2 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5320 PF17253.2 GAM27716.1 - 6.1 8.0 10.8 7.2 7.8 8.5 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) eIF-1a PF01176.19 GAM27717.1 - 3.1e-14 52.5 0.1 4.5e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Rap1_C PF11626.8 GAM27717.1 - 0.14 12.2 0.5 0.84 9.8 0.0 2.1 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pyr_redox_2 PF07992.14 GAM27718.1 - 1.2e-14 54.2 0.0 3.9e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAM27718.1 - 0.00015 21.8 0.0 0.039 13.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 GAM27718.1 - 0.00023 20.9 0.1 0.0027 17.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 GAM27718.1 - 0.00031 19.7 0.0 0.00087 18.2 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 GAM27718.1 - 0.01 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAM27718.1 - 0.014 15.9 0.0 0.062 13.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAM27718.1 - 0.16 11.2 1.1 13 5.0 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAM27718.1 - 0.2 10.9 0.0 0.43 9.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FNIP PF05725.12 GAM27719.1 - 9.2e-36 121.8 21.1 8.1e-10 38.7 0.0 8.7 2 2 7 10 10 10 10 FNIP Repeat LRR_4 PF12799.7 GAM27719.1 - 0.00031 21.1 9.6 0.47 11.0 0.0 5.0 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM27719.1 - 0.0051 16.5 3.0 0.66 9.8 0.2 3.6 3 2 1 4 4 4 2 Leucine rich repeat Cys_Met_Meta_PP PF01053.20 GAM27720.1 - 1.2e-152 507.9 0.0 1.3e-152 507.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAM27720.1 - 1.6e-06 27.6 0.1 2.3e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAM27720.1 - 0.00032 19.8 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAM27720.1 - 0.0018 17.6 0.1 0.0035 16.7 0.1 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ArfGap PF01412.18 GAM27721.1 - 4.5e-25 88.0 3.1 1.1e-24 86.7 3.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SH3_9 PF14604.6 GAM27721.1 - 1.3e-07 31.4 0.4 1.2e-06 28.2 0.4 2.5 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM27721.1 - 5.7e-07 29.0 0.1 1.5e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAM27721.1 - 0.00018 21.1 0.0 0.0011 18.6 0.0 2.3 2 1 0 2 2 2 1 Variant SH3 domain RBD PF02196.15 GAM27721.1 - 0.00042 20.3 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 Raf-like Ras-binding domain PH_2 PF08458.10 GAM27721.1 - 0.092 13.1 0.1 0.22 11.9 0.1 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PI3K_rbd PF00794.18 GAM27721.1 - 0.098 12.8 0.5 0.31 11.2 0.1 2.0 2 0 0 2 2 2 0 PI3-kinase family, ras-binding domain Pep3_Vps18 PF05131.14 GAM27722.1 - 1.7e-44 151.2 0.0 8.8e-44 148.9 0.0 2.3 3 0 0 3 3 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 GAM27722.1 - 7e-12 45.4 3.0 7e-12 45.4 3.0 3.2 2 1 0 2 2 2 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 GAM27722.1 - 1.6e-05 24.7 1.4 9.9e-05 22.2 0.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GAM27722.1 - 0.0002 20.9 0.6 0.0002 20.9 0.6 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 GAM27722.1 - 0.00056 20.2 1.6 0.0017 18.6 1.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM27722.1 - 0.001 18.8 2.8 0.001 18.8 2.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 GAM27722.1 - 0.0014 18.7 0.5 0.0035 17.4 0.5 1.6 1 0 0 1 1 1 1 KIAA1045 RING finger DUF2175 PF09943.9 GAM27722.1 - 0.0033 17.7 0.2 0.012 15.9 0.2 2.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_11 PF17123.5 GAM27722.1 - 0.0035 17.1 3.9 0.0099 15.6 3.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 GAM27722.1 - 0.0035 17.3 0.5 0.0094 16.0 0.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3H2C3 PF17122.5 GAM27722.1 - 0.021 14.8 2.6 0.048 13.7 2.6 1.6 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4 PF00097.25 GAM27722.1 - 0.052 13.4 1.1 0.15 12.0 1.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_1 PF00515.28 GAM27722.1 - 0.1 12.5 9.0 2.2 8.2 0.7 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 GAM27722.1 - 0.15 12.4 0.7 0.54 10.6 0.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_7 PF13176.6 GAM27722.1 - 0.15 12.2 7.2 23 5.3 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM27722.1 - 0.31 11.4 6.4 51 4.5 0.3 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Vps39_2 PF10367.9 GAM27722.1 - 0.37 11.3 3.8 0.29 11.6 0.2 2.5 3 0 0 3 3 2 0 Vacuolar sorting protein 39 domain 2 TPR_2 PF07719.17 GAM27722.1 - 1.8 8.8 6.1 11 6.4 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Peptidase_M1 PF01433.20 GAM27723.1 - 1.2e-74 250.6 5.7 2.2e-74 249.7 5.7 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 GAM27723.1 - 4.9e-49 167.6 0.5 4.9e-49 167.6 0.5 2.3 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 GAM27723.1 - 9.8e-44 149.8 3.8 1.4e-42 146.0 1.0 2.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain CBFD_NFYB_HMF PF00808.23 GAM27724.1 - 1.3e-18 67.1 0.5 2e-18 66.4 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAM27724.1 - 3.5e-12 46.8 0.7 3.5e-12 46.8 0.7 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.13 GAM27724.1 - 0.00045 20.3 23.5 0.00045 20.3 23.5 1.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CENP-X PF09415.10 GAM27724.1 - 0.065 13.6 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TetR_C_37 PF18665.1 GAM27724.1 - 1.6 9.3 4.5 17 6.0 0.6 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ndc1_Nup PF09531.10 GAM27724.1 - 2.9 6.5 8.9 3.9 6.1 8.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 GAM27724.1 - 8.6 5.0 7.5 12 4.5 7.5 1.1 1 0 0 1 1 1 0 Presenilin Methyltrans_SAM PF10672.9 GAM27725.1 - 4.1e-18 65.6 0.0 5.6e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 GAM27725.1 - 0.019 14.6 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_24 PF13578.6 GAM27725.1 - 0.1 13.7 0.0 0.25 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 GAM27725.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Peptidase_C25_C PF03785.14 GAM27726.1 - 0.066 13.1 0.9 0.15 11.9 0.9 1.7 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain Arm PF00514.23 GAM27726.1 - 8.7 6.5 7.8 40 4.4 0.3 3.7 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF676 PF05057.14 GAM27727.1 - 0.00079 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAM27727.1 - 0.005 16.6 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAM27727.1 - 0.056 14.0 0.0 0.088 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Arm_2 PF04826.13 GAM27727.1 - 0.061 12.8 5.3 0.13 11.7 0.2 2.4 2 1 1 3 3 3 0 Armadillo-like XRN_M PF17846.1 GAM27728.1 - 1.4e-110 370.3 7.6 1.4e-110 370.3 7.6 4.5 3 2 0 3 3 3 1 Xrn1 helical domain XRN_N PF03159.18 GAM27728.1 - 4.5e-95 317.7 0.1 4.5e-95 317.7 0.1 4.3 4 0 0 4 4 4 2 XRN 5'-3' exonuclease N-terminus Peptidase_M24 PF00557.24 GAM27729.1 - 3.3e-55 187.0 0.0 4.9e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAM27729.1 - 2e-27 95.3 0.1 4.9e-27 94.1 0.1 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 GAM27729.1 - 0.058 13.4 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) HAP1_N PF04849.13 GAM27730.1 - 0.00029 20.1 2.0 0.00029 20.1 2.0 2.0 2 0 0 2 2 2 1 HAP1 N-terminal conserved region bZIP_1 PF00170.21 GAM27730.1 - 0.0008 19.5 12.9 0.0037 17.3 12.8 2.1 1 1 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 GAM27730.1 - 0.02 15.5 0.3 0.02 15.5 0.3 3.1 3 0 0 3 3 3 0 Initiation control protein YabA Herpes_pp85 PF04637.12 GAM27730.1 - 0.022 13.2 9.2 0.057 11.8 9.2 1.6 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Semialdhyde_dh PF01118.24 GAM27730.1 - 0.048 14.1 0.2 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain YafO_toxin PF13957.6 GAM27730.1 - 0.097 12.7 0.0 0.097 12.7 0.0 2.4 3 0 0 3 3 3 0 Toxin YafO, type II toxin-antitoxin system SUIM_assoc PF16619.5 GAM27730.1 - 0.14 12.2 21.2 1.8 8.7 0.2 4.1 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PNRC PF15365.6 GAM27731.1 - 3e-07 30.0 4.2 9.7e-07 28.4 4.2 2.0 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif DUF1394 PF07159.12 GAM27733.1 - 5e-125 416.8 0.3 5.7e-125 416.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Complex1_LYR PF05347.15 GAM27734.1 - 9.9e-08 31.9 0.5 9.9e-08 31.9 0.5 1.8 1 1 1 2 2 2 1 Complex 1 protein (LYR family) EF-hand_3 PF09069.11 GAM27734.1 - 0.019 15.3 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 EF-hand RmlD_sub_bind PF04321.17 GAM27735.1 - 1e-11 44.5 0.0 6.1e-10 38.7 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 GAM27735.1 - 5.4e-11 42.4 0.0 2.8e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM27735.1 - 8.8e-10 38.8 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAM27735.1 - 7.1e-08 31.8 0.2 2e-07 30.3 0.2 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAM27735.1 - 5.2e-07 29.4 0.2 1.3e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAM27735.1 - 1.4e-06 28.0 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 GAM27735.1 - 1.2e-05 24.6 0.8 0.4 9.8 0.1 3.2 2 1 1 3 3 3 3 Male sterility protein adh_short PF00106.25 GAM27735.1 - 0.0039 16.7 0.0 0.0092 15.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 GAM27735.1 - 0.02 14.0 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 GAM27735.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PdaC PF13739.6 GAM27736.1 - 0.18 12.8 2.1 0.33 11.9 2.1 1.5 1 0 0 1 1 1 0 Deacetylase PdaC Prenyltransf PF01255.19 GAM27737.1 - 3.2e-70 236.1 0.3 3.2e-70 236.1 0.3 1.7 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Zip PF02535.22 GAM27737.1 - 0.00099 18.4 2.9 0.0054 16.0 2.1 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter Presenilin PF01080.17 GAM27737.1 - 0.012 14.5 7.9 0.013 14.3 6.0 1.9 2 0 0 2 2 2 0 Presenilin KIX PF02172.16 GAM27737.1 - 0.024 14.9 0.2 0.083 13.2 0.2 1.9 1 0 0 1 1 1 0 KIX domain DUF2654 PF10849.8 GAM27737.1 - 0.038 14.2 2.0 0.12 12.6 2.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) Otopetrin PF03189.13 GAM27737.1 - 1.5 7.6 9.8 3.7 6.3 9.7 1.8 1 1 0 1 1 1 0 Otopetrin Spindle_Spc25 PF08234.12 GAM27738.1 - 1.1e-22 79.9 1.3 2.5e-22 78.9 0.1 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 EzrA PF06160.12 GAM27738.1 - 0.0012 17.1 6.5 0.0012 17.1 6.5 1.5 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA BLOC1_2 PF10046.9 GAM27738.1 - 0.03 14.6 3.7 0.13 12.5 1.7 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Arabinose_bd PF12625.7 GAM27738.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Arabinose-binding domain of AraC transcription regulator, N-term NTPase_1 PF03266.15 GAM27738.1 - 0.24 11.3 3.0 0.35 10.8 1.8 1.8 2 0 0 2 2 2 0 NTPase TMF_DNA_bd PF12329.8 GAM27738.1 - 0.35 10.9 7.7 0.32 11.0 4.5 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.8 GAM27738.1 - 0.72 9.1 11.3 0.023 14.0 4.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DASH_Dad4 PF08650.10 GAM27738.1 - 2.1 8.4 7.9 1.5 8.8 1.8 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad4 DUF4200 PF13863.6 GAM27738.1 - 2.1 8.8 10.2 2.1 8.8 8.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) zf-C4H2 PF10146.9 GAM27738.1 - 9.1 6.5 11.6 7.3 6.8 10.6 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein RhoGAP PF00620.27 GAM27739.1 - 6.9e-28 97.4 0.1 2.8e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 GAM27739.1 - 2.4e-11 43.7 0.1 9.2e-11 41.9 0.1 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Muted PF14942.6 GAM27739.1 - 1.2 9.4 6.0 0.74 10.1 2.7 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein TRAP_alpha PF03896.16 GAM27740.1 - 6.7e-41 140.4 0.1 7.3e-41 140.2 0.1 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit ATP19 PF11022.8 GAM27740.1 - 0.011 16.1 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 ATP synthase subunit K Chordopox_A13L PF05961.11 GAM27740.1 - 0.053 13.8 0.0 0.053 13.8 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF4352 PF11611.8 GAM27740.1 - 0.057 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) Ras PF00071.22 GAM27741.1 - 2.8e-63 212.3 0.8 3.3e-63 212.1 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM27741.1 - 9.8e-35 119.4 0.1 1.8e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM27741.1 - 6.1e-16 58.4 0.1 7.6e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAM27741.1 - 1.9e-05 24.6 0.8 0.15 12.0 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 GAM27741.1 - 4.6e-05 22.9 0.1 5.3e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM27741.1 - 0.00019 21.1 0.8 0.00053 19.6 0.8 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM27741.1 - 0.00033 20.7 0.4 0.00051 20.1 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 GAM27741.1 - 0.00072 20.0 0.1 0.27 11.6 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 GAM27741.1 - 0.0011 18.4 0.1 0.0014 18.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 GAM27741.1 - 0.0075 15.8 0.0 0.057 13.0 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 GAM27741.1 - 0.021 14.3 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 GAM27741.1 - 0.025 14.6 0.0 0.047 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM27741.1 - 0.032 14.5 0.1 0.14 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAM27741.1 - 0.036 13.8 0.1 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAM27741.1 - 0.038 14.4 0.1 0.058 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 GAM27741.1 - 0.059 12.8 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein PV_NSP1 PF12433.8 GAM27742.1 - 0.022 15.1 0.1 0.15 12.4 0.1 2.4 1 0 0 1 1 1 0 Parvovirus non-structural protein 1 Las1 PF04031.13 GAM27743.1 - 6.5e-40 136.7 4.0 1.3e-39 135.7 4.0 1.5 1 0 0 1 1 1 1 Las1-like BTB PF00651.31 GAM27744.1 - 4e-16 59.2 0.7 3.8e-09 36.7 0.1 2.8 2 1 1 3 3 3 2 BTB/POZ domain BACK PF07707.15 GAM27744.1 - 2.1e-10 40.6 5.1 7.8e-09 35.6 0.1 2.9 3 0 0 3 3 3 2 BTB And C-terminal Kelch SUIM_assoc PF16619.5 GAM27744.1 - 2.9e-06 27.3 0.0 0.037 14.1 0.0 3.6 2 1 1 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 GAM27745.1 - 5.5e-20 71.7 11.5 2.1e-09 37.8 0.3 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM27745.1 - 1.9e-19 69.8 4.2 1.3e-05 25.6 0.0 4.6 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM27745.1 - 3.6e-18 65.4 13.7 9.3e-08 32.2 0.5 4.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM27745.1 - 2.8e-14 52.8 12.9 0.0014 18.9 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 GAM27745.1 - 6.8e-12 44.5 9.6 0.018 15.6 0.0 6.3 6 1 0 6 6 6 3 Ankyrin repeat L27_N PF09060.10 GAM27745.1 - 3.3 7.8 5.0 4.5 7.4 0.2 2.9 3 0 0 3 3 3 0 L27_N Cyclin PF08613.11 GAM27746.1 - 0.0077 16.6 0.7 0.0077 16.6 0.7 2.9 2 1 0 2 2 2 1 Cyclin SUIM_assoc PF16619.5 GAM27746.1 - 0.052 13.6 0.7 0.052 13.6 0.7 3.9 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 IFT81_CH PF18383.1 GAM27746.1 - 0.27 11.5 4.1 0.22 11.8 0.2 2.3 2 0 0 2 2 2 0 Intraflagellar transport 81 calponin homology domain TFIIA PF03153.13 GAM27746.1 - 1.6 8.7 23.8 2.3 8.1 23.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4446 PF14584.6 GAM27746.1 - 5.2 7.1 7.0 0.31 11.0 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Methyltransf_3 PF01596.17 GAM27747.1 - 7.5e-58 195.2 0.5 8.4e-58 195.0 0.5 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAM27747.1 - 4.8e-13 50.0 0.0 6.2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM27747.1 - 0.00026 21.6 0.0 0.00038 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAM27747.1 - 0.031 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 GAM27747.1 - 0.031 13.6 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 GAM27747.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Kelch_1 PF01344.25 GAM27748.1 - 3.1e-12 45.9 1.2 4.9e-05 22.8 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 GAM27748.1 - 1.3e-11 44.3 3.5 1.1e-05 25.3 0.3 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM27748.1 - 1.3e-07 31.6 7.1 0.018 15.3 0.1 4.0 3 1 1 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAM27748.1 - 0.0013 19.0 0.5 1.7 9.0 0.0 3.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM27748.1 - 0.0034 17.3 2.8 1.1 9.4 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 GAM27748.1 - 0.027 14.5 6.5 0.088 12.8 0.1 3.2 3 0 0 3 3 3 0 Kelch motif RPW8 PF05659.11 GAM27748.1 - 0.047 13.4 0.9 0.12 12.0 0.9 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3347 PF11827.8 GAM27748.1 - 2.1 8.5 7.4 3.2 7.9 6.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Nckap1 PF09735.9 GAM27749.1 - 6.7e-05 21.1 3.3 8.4e-05 20.8 3.3 1.2 1 0 0 1 1 1 1 Membrane-associated apoptosis protein zf-B_box PF00643.24 GAM27749.1 - 0.0012 18.9 7.1 0.0026 17.9 7.1 1.5 1 0 0 1 1 1 1 B-box zinc finger CALCOCO1 PF07888.11 GAM27749.1 - 0.024 13.5 1.5 0.039 12.8 1.5 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like RPW8 PF05659.11 GAM27749.1 - 0.091 12.4 4.4 0.076 12.7 1.0 2.4 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Seryl_tRNA_N PF02403.22 GAM27749.1 - 0.35 11.1 4.2 0.25 11.6 1.7 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FYVE_2 PF02318.16 GAM27749.1 - 2.8 8.2 10.3 0.23 11.7 4.1 2.3 2 2 0 2 2 2 0 FYVE-type zinc finger PDCD7 PF16021.5 GAM27749.1 - 2.9 6.9 8.4 2.6 7.1 6.2 2.0 2 1 0 2 2 2 0 Programmed cell death protein 7 YgaB PF14182.6 GAM27749.1 - 4.9 7.6 6.8 2.2 8.7 0.1 3.3 3 2 1 4 4 4 0 YgaB-like protein DUF3347 PF11827.8 GAM27749.1 - 6.3 7.0 9.6 0.16 12.2 1.8 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3347) FGGY_C PF02782.16 GAM27750.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Kelch_6 PF13964.6 GAM27751.1 - 0.001 19.3 2.5 0.029 14.7 0.1 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 GAM27752.1 - 0.0039 17.1 0.0 0.67 10.0 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 GAM27752.1 - 0.007 16.6 0.5 1.7 9.0 0.0 3.1 3 0 0 3 3 3 1 Kelch motif DUF3015 PF11220.8 GAM27752.1 - 0.093 12.6 0.2 0.23 11.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3015) Kelch_1 PF01344.25 GAM27752.1 - 0.27 10.8 1.5 8.3 6.1 0.2 2.9 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 GAM27753.1 - 3.2e-12 46.3 4.7 7e-05 22.8 0.1 4.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM27753.1 - 5.6e-11 41.9 5.8 0.00078 19.0 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 GAM27753.1 - 2e-10 40.6 14.1 1.5e-05 25.1 0.0 4.6 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 GAM27753.1 - 5.2e-06 26.2 3.7 0.023 14.7 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 GAM27753.1 - 4.6e-05 23.6 1.5 1.3 9.4 0.1 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM27753.1 - 0.016 15.2 3.1 1.1 9.3 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Methyltransf_3 PF01596.17 GAM27754.1 - 1.6e-64 217.0 0.1 1.9e-64 216.8 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAM27754.1 - 1.9e-13 51.4 0.0 2.9e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM27754.1 - 2.4e-06 28.2 0.0 6.3e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM27754.1 - 2.6e-06 27.3 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAM27754.1 - 0.0029 17.0 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 GAM27754.1 - 0.0089 15.7 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.12 GAM27754.1 - 0.011 16.4 0.0 0.019 15.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 GAM27754.1 - 0.021 14.8 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 GAM27754.1 - 0.028 13.8 0.2 0.24 10.7 0.0 2.0 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 GAM27754.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAM27754.1 - 0.13 13.0 0.0 0.34 11.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Ferritin PF00210.24 GAM27755.1 - 0.039 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Ferritin-like domain DUF4061 PF13270.6 GAM27755.1 - 0.096 13.0 1.4 0.26 11.6 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) zf-AD PF07776.15 GAM27755.1 - 1.1 9.5 3.9 0.69 10.2 0.6 2.5 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) EamA PF00892.20 GAM27756.1 - 7.8e-25 87.6 37.8 1.4e-12 48.0 14.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family NLPC_P60 PF00877.19 GAM27757.1 - 2.5e-12 46.7 0.0 2.2e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 NlpC/P60 family DUF1175 PF06672.11 GAM27757.1 - 0.14 11.8 0.0 13 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1175) Coilin_N PF15862.5 GAM27758.1 - 1.9e-12 47.2 5.3 1.9e-12 47.2 5.3 3.8 2 1 1 3 3 3 1 Coilin N-terminus Macoilin PF09726.9 GAM27758.1 - 0.13 10.8 27.3 0.019 13.5 21.3 1.9 2 0 0 2 2 2 0 Macoilin family Nop14 PF04147.12 GAM27758.1 - 2.2 6.4 48.5 0.11 10.7 39.5 2.0 2 0 0 2 2 2 0 Nop14-like family LAP1C PF05609.12 GAM27758.1 - 5 6.1 33.0 0.22 10.6 24.0 2.0 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) SDA1 PF05285.12 GAM27758.1 - 7.4 5.9 47.1 2.7 7.3 38.7 2.3 2 0 0 2 2 2 0 SDA1 WD40 PF00400.32 GAM27759.1 - 2.1e-27 94.8 7.6 1e-05 26.2 0.0 8.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Bromodomain PF00439.25 GAM27759.1 - 1.4e-14 53.9 0.1 3.2e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 Bromodomain ANAPC4_WD40 PF12894.7 GAM27759.1 - 8.3e-05 22.8 0.2 0.88 9.9 0.1 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 GAM27759.1 - 0.032 12.5 0.0 0.1 10.9 0.0 1.6 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz YL1 PF05764.13 GAM27759.1 - 0.17 12.0 59.4 0.027 14.6 15.0 3.6 3 1 0 3 3 3 0 YL1 nuclear protein Lung_7-TM_R PF06814.13 GAM27760.1 - 5.7e-64 216.2 25.1 9.5e-64 215.5 25.1 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4131 PF13567.6 GAM27760.1 - 1.2 8.8 6.7 12 5.5 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Ammonium_transp PF00909.21 GAM27761.1 - 3.7e-106 355.2 31.2 4.2e-106 355.0 31.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family BT1 PF03092.16 GAM27761.1 - 0.0027 16.0 1.5 0.0071 14.6 1.5 1.8 1 0 0 1 1 1 1 BT1 family FxsA PF04186.13 GAM27761.1 - 8.9 6.5 14.8 3.8 7.7 1.3 3.6 3 0 0 3 3 3 0 FxsA cytoplasmic membrane protein Ank_5 PF13857.6 GAM27762.1 - 0.026 14.8 0.6 0.29 11.5 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Peptidase_M3 PF01432.20 GAM27763.1 - 1.9e-101 340.6 1.4 1.9e-101 340.6 1.4 1.5 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 GAM27763.1 - 0.28 10.8 0.5 0.48 10.0 0.5 1.3 1 0 0 1 1 1 0 Peptidase M50B-like STATa_Ig PF18214.1 GAM27764.1 - 2.8e-44 150.0 1.1 2.8e-44 150.0 1.1 2.1 2 0 0 2 2 2 1 STATa Immunoglobulin-like domain Dict-STAT-coil PF09267.10 GAM27764.1 - 1.3e-42 144.7 17.0 1.3e-42 144.7 17.0 2.0 2 0 0 2 2 2 1 Dictyostelium STAT, coiled coil EF-hand_12 PF17901.1 GAM27764.1 - 1.9e-42 143.6 2.8 4.7e-42 142.4 2.8 1.7 1 0 0 1 1 1 1 EF-hand fold domain SH2 PF00017.24 GAM27764.1 - 3e-10 40.1 0.0 8e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 GAM27764.1 - 0.0017 18.2 0.0 0.0053 16.6 0.0 1.8 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain PG_binding_1 PF01471.18 GAM27765.1 - 1.1e-07 31.9 0.0 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain YkuD PF03734.14 GAM27765.1 - 0.00077 19.9 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Adaptin_N PF01602.20 GAM27766.1 - 9.9e-117 390.7 10.4 1.2e-116 390.3 10.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 GAM27766.1 - 1.5e-26 92.8 0.0 9.6e-26 90.2 0.0 2.2 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 GAM27766.1 - 4.8e-18 65.5 0.2 1.4e-17 64.0 0.2 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 GAM27766.1 - 0.00061 19.9 6.3 0.048 13.7 0.1 2.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF5390 PF17365.2 GAM27766.1 - 0.012 15.8 0.2 0.041 14.2 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5390) Ribonuc_red_sm PF00268.21 GAM27767.1 - 1.3e-120 402.1 0.9 1.6e-120 401.8 0.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Pkinase PF00069.25 GAM27768.1 - 4.9e-65 219.5 0.0 4.9e-65 219.5 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27768.1 - 4.6e-25 88.4 0.0 4.6e-25 88.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM27768.1 - 0.00022 20.7 0.0 0.00022 20.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.25 GAM27769.1 - 3.5e-74 249.5 0.0 4.4e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27769.1 - 2.4e-36 125.4 0.0 3.4e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM27769.1 - 1.3e-06 28.0 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAM27769.1 - 4.2e-06 26.0 0.2 6e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 GAM27769.1 - 3e-05 23.0 0.0 5.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 GAM27769.1 - 0.00043 19.9 0.4 0.00071 19.2 0.4 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 GAM27769.1 - 0.0014 18.0 0.2 0.0022 17.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM27769.1 - 0.009 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 GAM27769.1 - 0.013 16.2 0.2 0.06 14.1 0.2 2.2 1 0 0 1 1 1 0 Protein kinase C terminal domain Choline_kinase PF01633.20 GAM27769.1 - 0.14 11.7 0.1 0.35 10.4 0.1 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Ank_2 PF12796.7 GAM27770.1 - 3.8e-13 49.8 0.8 7.1e-07 29.7 0.2 5.4 3 1 3 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM27770.1 - 5.9e-12 45.9 0.3 0.00021 21.8 0.1 5.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM27770.1 - 7.5e-09 35.1 5.3 0.15 12.7 0.0 7.1 7 1 1 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 GAM27770.1 - 9.5e-08 32.2 1.8 0.3 11.4 0.2 5.4 4 1 2 6 6 6 2 Ankyrin repeats (many copies) McrBC PF10117.9 GAM27770.1 - 0.071 12.2 0.1 0.18 10.9 0.1 1.6 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component Ras PF00071.22 GAM27772.1 - 1.3e-54 184.2 0.0 1.7e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM27772.1 - 1.4e-19 70.5 0.0 2.8e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM27772.1 - 4.9e-09 35.9 0.0 5.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM27772.1 - 8e-05 22.3 0.1 0.0022 17.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM27772.1 - 0.00018 21.5 0.0 0.00047 20.2 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM27772.1 - 0.00023 21.1 0.1 0.48 10.3 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAM27772.1 - 0.00083 18.9 0.0 0.0038 16.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PglD_N PF17836.1 GAM27772.1 - 0.093 13.4 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain CbiA PF01656.23 GAM27772.1 - 0.15 12.1 0.1 0.39 10.8 0.1 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PDEase_I PF00233.19 GAM27773.1 - 5.2e-77 258.8 5.7 9.5e-77 257.9 5.7 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 GAM27773.1 - 0.033 14.4 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 HD domain HEAT_UF PF18817.1 GAM27773.1 - 0.099 12.9 0.1 3.5 8.0 0.1 2.7 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 CDO_I PF05995.12 GAM27774.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I ABC-3 PF00950.17 GAM27774.1 - 0.064 12.7 0.4 0.86 9.1 0.9 2.0 2 0 0 2 2 2 0 ABC 3 transport family LIM PF00412.22 GAM27775.1 - 9.5e-13 48.2 7.3 1.1e-12 48.0 7.3 1.1 1 0 0 1 1 1 1 LIM domain YacG PF03884.14 GAM27775.1 - 0.32 10.8 7.2 1.8 8.4 0.2 2.1 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-RING_2 PF13639.6 GAM27775.1 - 0.33 11.3 6.9 1.5 9.2 6.9 2.1 1 1 0 1 1 1 0 Ring finger domain YdjO PF14169.6 GAM27775.1 - 0.67 9.7 0.0 0.67 9.7 0.0 2.8 2 1 1 3 3 3 0 Cold-inducible protein YdjO zf-B_box PF00643.24 GAM27775.1 - 0.71 10.1 11.9 4 7.7 8.3 2.6 2 1 1 3 3 3 0 B-box zinc finger Tmemb_14 PF03647.13 GAM27776.1 - 0.012 16.4 8.8 0.016 15.9 8.8 1.2 1 0 0 1 1 1 0 Transmembrane proteins 14C ANAPC_CDC26 PF10471.9 GAM27777.1 - 0.061 14.2 6.2 0.061 14.2 6.2 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 MRP-S33 PF08293.11 GAM27778.1 - 1.7e-07 31.4 2.4 7.3e-07 29.3 2.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 SNARE PF05739.19 GAM27779.1 - 3.2e-05 23.8 0.2 7.6e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 SNARE domain APG17 PF04108.12 GAM27779.1 - 0.0091 15.2 2.0 0.01 15.0 2.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF443 PF04276.12 GAM27779.1 - 0.018 14.9 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Pex24p PF06398.11 GAM27779.1 - 0.036 13.0 0.2 0.04 12.9 0.2 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin UcrQ PF02939.16 GAM27779.1 - 0.069 13.1 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 UcrQ family Synaptobrevin PF00957.21 GAM27779.1 - 0.8 9.5 6.5 3.4 7.5 3.0 2.3 1 1 1 2 2 2 0 Synaptobrevin Tweety PF04906.13 GAM27779.1 - 2.7 6.6 7.2 0.25 10.0 1.7 1.8 1 1 1 2 2 2 0 Tweety Orf78 PF06024.12 GAM27779.1 - 6.5 7.1 7.9 46 4.4 7.7 2.1 1 1 0 1 1 1 0 Orf78 (ac78) Ank_3 PF13606.6 GAM27781.1 - 0.00094 19.5 0.4 0.27 11.9 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 GAM27781.1 - 0.0058 17.2 0.0 0.019 15.5 0.0 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM27781.1 - 0.024 15.0 0.1 0.094 13.1 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM27781.1 - 0.026 15.1 0.1 0.19 12.4 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) ERG2_Sigma1R PF04622.12 GAM27782.1 - 1.4e-16 60.5 0.1 5.1e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 ERG2 and Sigma1 receptor like protein DUF4477 PF14780.6 GAM27783.1 - 1.8e-09 37.5 0.5 1.8e-09 37.5 0.5 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4477) DUF936 PF06075.12 GAM27783.1 - 0.22 10.4 15.7 0.3 10.0 15.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Ndc1_Nup PF09531.10 GAM27783.1 - 0.23 10.1 15.9 0.28 9.8 15.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 GAM27783.1 - 0.8 7.9 26.1 0.96 7.6 26.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LAP1C PF05609.12 GAM27783.1 - 1.3 8.1 19.6 1.7 7.7 19.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CAC1F_C PF16885.5 GAM27783.1 - 1.3 8.6 15.2 1.9 8.1 15.2 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term TFIIA PF03153.13 GAM27783.1 - 1.4 8.8 35.0 2 8.3 35.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CSG2 PF16965.5 GAM27783.1 - 3 6.7 11.9 5.9 5.7 11.9 1.5 1 1 0 1 1 1 0 Ceramide synthase regulator GREB1 PF15782.5 GAM27783.1 - 4.5 4.3 22.2 5.8 3.9 22.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDK5_activator PF03261.15 GAM27783.1 - 5.9 6.3 27.2 10 5.6 27.2 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Suf PF05843.14 GAM27783.1 - 7.6 6.4 26.4 11 5.9 26.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 GAM27783.1 - 8.7 6.3 12.5 16 5.5 12.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SRF-TF PF00319.18 GAM27784.1 - 2.4e-21 75.0 0.1 3.6e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TERB2 PF15101.6 GAM27784.1 - 0.0057 16.7 4.2 0.01 15.9 4.2 1.5 1 0 0 1 1 1 1 Telomere-associated protein TERB2 Spt20 PF12090.8 GAM27784.1 - 0.018 14.7 25.8 0.034 13.8 25.8 1.5 1 0 0 1 1 1 0 Spt20 family CPSF100_C PF13299.6 GAM27784.1 - 0.3 11.2 4.0 0.59 10.3 4.0 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 GAM27784.1 - 0.39 10.7 38.4 0.75 9.7 38.5 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.12 GAM27784.1 - 0.56 8.1 4.2 0.77 7.7 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAT1 PF09770.9 GAM27784.1 - 0.59 8.3 16.7 0.73 8.0 16.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 GAM27784.1 - 1.2 7.8 7.9 1.7 7.3 7.9 1.2 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 GAM27784.1 - 3.5 7.5 24.2 2.9 7.8 23.0 1.4 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4407 PF14362.6 GAM27784.1 - 4 6.7 9.4 6.3 6.1 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) REC114-like PF15165.6 GAM27784.1 - 4.7 6.9 12.4 10 5.8 11.8 1.7 2 0 0 2 2 2 0 Meiotic recombination protein REC114-like DUF3408 PF11888.8 GAM27784.1 - 5.3 7.2 10.9 1.2 9.2 7.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) EIIBC-GUT_N PF03612.14 GAM27784.1 - 7.9 6.2 7.6 16 5.2 7.6 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4834 PF16118.5 GAM27784.1 - 8.2 7.5 11.6 1.9 9.5 7.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Glucokinase PF02685.16 GAM27785.1 - 4.9e-20 71.8 0.0 6.8e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 GAM27785.1 - 5.4e-08 32.7 0.6 0.0022 17.5 0.0 2.4 2 1 0 2 2 2 2 ROK family FGGY_N PF00370.21 GAM27785.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Hydant_A_N PF05378.13 GAM27785.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DUF2039 PF10217.9 GAM27786.1 - 1.5e-25 89.4 15.0 1.5e-25 89.4 15.0 2.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2039) Nop14 PF04147.12 GAM27786.1 - 0.0091 14.3 38.6 0.011 14.1 38.6 1.1 1 0 0 1 1 1 1 Nop14-like family Paired_CXXCH_1 PF09699.10 GAM27786.1 - 0.013 15.3 0.5 0.013 15.3 0.5 2.9 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) zinc-ribbons_6 PF07191.12 GAM27786.1 - 0.029 14.4 13.1 0.055 13.5 13.1 1.5 1 0 0 1 1 1 0 zinc-ribbons CDC27 PF09507.10 GAM27786.1 - 0.5 9.7 26.7 0.7 9.2 26.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BUD22 PF09073.10 GAM27786.1 - 1.8 7.8 31.4 2.2 7.5 31.4 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAM27786.1 - 7.9 4.6 28.6 10 4.3 28.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DZR PF12773.7 GAM27786.1 - 8.1 6.6 15.4 5.6 7.1 9.1 2.3 1 1 1 2 2 2 0 Double zinc ribbon Cellulase PF00150.18 GAM27787.1 - 3.1e-30 105.6 0.1 4.4e-30 105.1 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 GAM27787.1 - 4.4e-17 62.4 0.1 9.4e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_42 PF02449.15 GAM27787.1 - 0.0028 17.0 0.9 0.0048 16.3 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_1 PF00232.18 GAM27787.1 - 0.029 12.8 0.0 0.047 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 MFS_1 PF07690.16 GAM27788.1 - 4.5e-29 101.5 34.9 4.3e-15 55.5 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM27788.1 - 5.8e-10 38.6 26.1 1e-07 31.2 0.2 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 GAM27788.1 - 0.053 12.1 29.9 0.08 11.5 29.9 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein TMEM100 PF16311.5 GAM27788.1 - 0.92 9.1 3.8 19 4.8 0.0 3.3 3 0 0 3 3 3 0 Transmembrane protein 100 Ank_5 PF13857.6 GAM27790.1 - 1.3e-51 171.9 21.5 2.6e-05 24.4 0.1 14.2 3 3 11 14 14 14 14 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM27790.1 - 2.8e-50 168.8 35.5 1.4e-09 38.4 0.3 7.2 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM27790.1 - 6.1e-44 147.8 19.0 4.1e-06 27.2 0.1 9.8 7 3 3 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM27790.1 - 3.9e-18 63.6 5.9 6.8 7.6 0.0 13.4 14 1 1 15 15 15 2 Ankyrin repeat DUF1242 PF06842.12 GAM27790.1 - 7.1e-13 48.1 1.0 2e-12 46.7 1.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Ank PF00023.30 GAM27790.1 - 1.1e-07 31.9 9.0 24 5.6 0.0 11.2 3 2 5 8 8 8 0 Ankyrin repeat DUF5049 PF16468.5 GAM27790.1 - 8e-07 28.9 0.1 54 3.8 0.0 8.5 10 1 1 11 11 11 0 Domain of unknown function (DUF5049) Ribosomal_L30 PF00327.20 GAM27790.1 - 0.11 12.4 0.0 4.9 7.1 0.0 3.6 4 0 0 4 4 4 0 Ribosomal protein L30p/L7e SGTA_dimer PF16546.5 GAM27790.1 - 0.13 12.0 0.8 41 4.0 0.0 4.8 6 0 0 6 6 6 0 Homodimerisation domain of SGTA TSLP PF15216.6 GAM27790.1 - 6.9 7.0 6.6 49 4.2 0.1 4.2 4 1 2 6 6 6 0 Thymic stromal lymphopoietin LSM PF01423.22 GAM27791.1 - 3.6e-10 39.4 0.1 1e-09 38.0 0.1 1.8 1 1 0 1 1 1 1 LSM domain TFIIA PF03153.13 GAM27791.1 - 0.00033 20.8 6.3 0.00033 20.8 6.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PRCC PF10253.9 GAM27791.1 - 0.00078 20.3 3.4 0.001 19.9 3.4 1.2 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Ecl1 PF12855.7 GAM27791.1 - 0.0052 18.0 14.8 0.03 15.5 13.5 2.0 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins Ndc1_Nup PF09531.10 GAM27791.1 - 0.18 10.5 7.8 0.2 10.3 7.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ring_hydroxyl_A PF00848.19 GAM27791.1 - 1.6 8.6 5.7 2.3 8.1 5.7 1.2 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Nucleo_P87 PF07267.11 GAM27791.1 - 3 6.6 7.7 3.3 6.5 7.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FSA_C PF10479.9 GAM27791.1 - 3.3 5.7 7.4 4.5 5.3 7.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NUDIX PF00293.28 GAM27792.1 - 1.8e-06 28.0 0.0 4.9e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 NUDIX domain RhoGAP PF00620.27 GAM27793.1 - 3.3e-34 117.9 0.0 7e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain CENP-N PF05238.13 GAM27793.1 - 0.00066 19.1 4.2 0.0013 18.2 4.2 1.4 1 0 0 1 1 1 1 Kinetochore protein CHL4 like RNA_polI_A34 PF08208.11 GAM27793.1 - 0.0042 17.2 17.9 0.0042 17.2 17.9 2.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 CDC27 PF09507.10 GAM27793.1 - 0.0054 16.2 14.9 0.0054 16.2 14.9 2.5 2 1 1 4 4 4 1 DNA polymerase subunit Cdc27 DUF3987 PF13148.6 GAM27793.1 - 0.43 9.5 8.2 0.64 9.0 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Tho2 PF11262.8 GAM27793.1 - 3 7.0 8.3 5.6 6.1 7.1 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Draxin PF15550.6 GAM27793.1 - 9.7 6.0 16.3 0.26 11.1 9.3 1.8 2 0 0 2 2 2 0 Draxin FNIP PF05725.12 GAM27794.1 - 4.8e-97 317.9 26.4 5.8e-15 55.2 0.2 9.3 9 0 0 9 9 9 8 FNIP Repeat CBM_20 PF00686.19 GAM27795.1 - 2.1e-19 69.2 0.0 3.5e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Starch binding domain Kin17_mid PF10357.9 GAM27796.1 - 7.9e-47 158.3 2.6 7.9e-47 158.3 2.6 2.3 2 1 1 3 3 3 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 GAM27796.1 - 5e-14 52.2 1.5 2.5e-12 46.7 0.8 2.6 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain KOW PF00467.29 GAM27796.1 - 0.00016 21.5 0.1 0.00087 19.2 0.1 2.2 2 0 0 2 2 2 1 KOW motif MFA1_2 PF17317.2 GAM27796.1 - 1.3 8.9 4.3 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 UPRTase PF14681.6 GAM27797.1 - 1.3e-62 210.9 0.0 2.2e-62 210.2 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 GAM27797.1 - 1.3e-54 185.0 0.2 2.1e-54 184.3 0.2 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 GAM27797.1 - 0.00013 22.6 0.0 0.00013 22.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 GAM27797.1 - 0.0028 18.1 0.9 2 8.8 0.1 2.8 3 0 0 3 3 3 2 AAA domain CoaE PF01121.20 GAM27797.1 - 0.0086 15.8 0.6 1.9 8.1 0.3 2.3 2 0 0 2 2 2 2 Dephospho-CoA kinase Cytidylate_kin PF02224.18 GAM27797.1 - 0.0094 15.7 0.2 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Cytidylate kinase Zeta_toxin PF06414.12 GAM27797.1 - 0.013 14.8 0.0 0.065 12.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 GAM27797.1 - 0.016 15.4 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pribosyltran PF00156.27 GAM27797.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Pep_deformylase PF01327.21 GAM27798.1 - 2.6e-50 170.1 0.0 3.5e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase ComX PF05952.12 GAM27798.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacillus competence pheromone ComX FNIP PF05725.12 GAM27799.1 - 1.2e-51 172.6 30.0 4e-14 52.5 0.8 8.5 7 1 2 9 9 9 8 FNIP Repeat YliH PF10799.8 GAM27799.1 - 0.22 11.5 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) LRR_4 PF12799.7 GAM27799.1 - 6.5 7.3 13.6 2.1 8.9 1.0 4.8 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) Coiled PF05710.12 GAM27800.1 - 1.5e-06 29.0 3.9 1.6e-06 28.8 3.9 1.0 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 GAM27801.1 - 1.4e-06 29.0 8.3 1.6e-06 28.9 8.3 1.1 1 0 0 1 1 1 1 Coiled coil DUF3275 PF11679.8 GAM27801.1 - 0.098 12.6 0.0 0.11 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) FNIP PF05725.12 GAM27802.1 - 2.2e-31 107.7 4.5 2.3e-14 53.2 0.0 3.0 2 1 1 3 3 3 3 FNIP Repeat WD40 PF00400.32 GAM27802.1 - 0.082 13.8 2.5 9.5 7.3 0.1 4.1 1 1 1 3 3 3 0 WD domain, G-beta repeat Tecti-min-caps PF09300.10 GAM27802.1 - 0.099 12.7 0.2 31 4.7 0.0 3.4 3 1 1 4 4 4 0 Tectiviridae, minor capsid NAR PF16251.5 GAM27802.1 - 0.19 12.4 0.0 11 6.7 0.0 2.3 1 1 1 2 2 2 0 Nucleic acid-binding domain (NAR) Man-6-P_recep PF02157.15 GAM27804.1 - 0.00085 18.5 0.1 0.002 17.3 0.1 1.5 1 0 0 1 1 1 1 Mannose-6-phosphate receptor VSP PF03302.13 GAM27804.1 - 0.0071 15.2 1.0 0.012 14.5 0.3 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF2434 PF10361.9 GAM27804.1 - 0.013 14.5 0.5 0.029 13.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) DUF2034 PF10356.9 GAM27804.1 - 0.036 13.5 0.2 0.24 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2034) DUF1494 PF07379.11 GAM27804.1 - 0.2 11.5 0.9 1 9.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1494) Sec1 PF00995.23 GAM27805.1 - 1e-119 401.4 0.0 1.2e-119 401.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DPBB_1 PF03330.18 GAM27807.1 - 4.5e-14 52.5 1.1 2e-13 50.4 0.1 2.6 2 1 0 2 2 2 1 Lytic transglycolase Cerato-platanin PF07249.12 GAM27807.1 - 7.2e-05 22.9 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 Cerato-platanin Keratin_matx PF04579.12 GAM27807.1 - 0.0097 16.2 2.4 0.0097 16.2 2.4 1.8 1 1 0 1 1 1 1 Keratin, high-sulphur matrix protein Barwin PF00967.17 GAM27807.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Barwin family PCMT PF01135.19 GAM27808.1 - 2.7e-64 216.8 0.0 3.6e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GAM27808.1 - 0.00015 21.6 0.2 0.00023 21.0 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM27808.1 - 0.00036 21.2 0.0 0.00074 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAM27808.1 - 0.0014 18.2 0.1 0.0041 16.7 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 GAM27808.1 - 0.0026 17.7 0.3 0.0054 16.7 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAM27808.1 - 0.0026 17.7 0.1 0.0046 17.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM27808.1 - 0.0055 17.3 0.2 0.016 15.8 0.1 2.0 2 1 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 GAM27808.1 - 0.007 15.8 0.2 0.0095 15.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.10 GAM27808.1 - 0.0075 16.0 0.0 0.016 14.9 0.0 1.5 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_3 PF01596.17 GAM27808.1 - 0.032 13.4 0.0 0.075 12.2 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase Fibrillarin PF01269.17 GAM27808.1 - 0.052 12.7 1.2 0.98 8.5 0.2 2.3 1 1 1 2 2 2 0 Fibrillarin FtsJ PF01728.19 GAM27808.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 GAM27808.1 - 0.14 11.5 0.1 0.23 10.7 0.1 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAM27808.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Exo_endo_phos PF03372.23 GAM27809.1 - 7.1e-05 22.4 0.1 0.00018 21.1 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ARS2 PF04959.13 GAM27809.1 - 0.074 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Arsenite-resistance protein 2 Atg8 PF02991.16 GAM27810.1 - 5.7e-43 145.3 0.3 6.8e-43 145.1 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 GAM27810.1 - 2.1e-07 31.3 0.0 2.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 BAR PF03114.18 GAM27811.1 - 1.4e-06 28.2 7.9 1.4e-06 28.1 6.6 1.7 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 GAM27811.1 - 6.4e-05 22.8 9.2 0.00018 21.3 9.2 1.8 1 1 0 1 1 1 1 BAR domain of APPL family STAT_alpha PF01017.20 GAM27811.1 - 0.25 11.2 4.8 0.59 10.0 4.8 1.5 1 0 0 1 1 1 0 STAT protein, all-alpha domain LCE PF14672.6 GAM27811.1 - 0.92 10.2 9.9 2 9.1 9.9 1.5 1 0 0 1 1 1 0 Late cornified envelope UPF0242 PF06785.11 GAM27811.1 - 2.5 8.2 9.4 0.18 11.9 3.6 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Kelch_4 PF13418.6 GAM27812.1 - 4e-09 36.4 3.7 0.018 15.0 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM27812.1 - 1.2e-06 27.9 2.8 0.025 14.2 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 GAM27812.1 - 1.7e-06 28.1 0.6 0.33 11.3 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 GAM27812.1 - 8e-06 26.0 5.0 0.3 11.4 0.1 5.6 6 1 0 6 6 6 2 Galactose oxidase, central domain Exo_endo_phos PF03372.23 GAM27813.1 - 0.015 14.8 1.1 0.08 12.4 1.1 2.0 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family PDDEXK_5 PF11645.8 GAM27813.1 - 0.06 13.3 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 PD-(D/E)XK endonuclease Cofilin_ADF PF00241.20 GAM27814.1 - 4.8e-31 107.1 0.2 5.6e-31 106.9 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF4476 PF14771.6 GAM27816.1 - 1.1e-18 67.2 2.0 1.3e-18 67.1 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) ATP-synt_ab_C PF00306.27 GAM27816.1 - 0.014 15.8 0.5 0.014 15.8 0.5 1.5 2 0 0 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain FragX_IP PF05994.11 GAM27817.1 - 8.9e-301 999.9 9.0 8.9e-301 999.9 9.0 1.6 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 GAM27817.1 - 1.7e-18 67.0 8.7 4.5e-18 65.5 8.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WXG100 PF06013.12 GAM27817.1 - 0.15 12.3 2.0 9.7 6.5 0.0 3.9 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Flavodoxin_NdrI PF07972.11 GAM27817.1 - 0.41 10.8 2.3 33 4.7 0.1 3.0 3 0 0 3 3 3 0 NrdI Flavodoxin like mRNA_cap_C PF03919.15 GAM27817.1 - 0.73 10.5 3.7 5 7.8 0.0 3.3 3 1 1 4 4 4 0 mRNA capping enzyme, C-terminal domain Cut12 PF11500.8 GAM27817.1 - 1.3 9.0 4.4 13 5.7 0.7 2.8 2 0 0 2 2 2 0 Spindle pole body formation-associated protein RGS PF00615.19 GAM27817.1 - 9.9 6.5 9.0 5 7.4 0.0 4.0 4 0 0 4 4 4 0 Regulator of G protein signaling domain EGF_2 PF07974.13 GAM27819.1 - 0.0023 18.2 14.1 0.005 17.2 14.1 1.6 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 GAM27819.1 - 0.067 13.5 10.4 0.16 12.3 10.4 1.7 1 0 0 1 1 1 0 EGF-like domain DUF5362 PF17319.2 GAM27819.1 - 0.078 12.8 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5362) RT_RNaseH PF17917.1 GAM27822.1 - 2.2e-32 111.5 0.1 5.1e-32 110.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAM27822.1 - 7.7e-24 84.4 0.9 2.4e-23 82.8 0.9 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 GAM27822.1 - 1.1e-22 79.9 0.1 2.8e-22 78.6 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GAM27822.1 - 2.9e-18 65.7 0.2 7.9e-18 64.3 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GAM27822.1 - 9.3e-16 58.1 0.0 3.3e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 GAM27822.1 - 0.00042 20.5 2.0 0.00045 20.4 0.1 2.1 2 0 0 2 2 2 1 H2C2 zinc finger MORN PF02493.20 GAM27824.1 - 3.5e-35 117.8 56.2 6.5e-07 28.9 2.1 12.2 11 2 2 13 13 13 10 MORN repeat DUF4746 PF15928.5 GAM27825.1 - 4.8 6.5 27.9 1.5 8.2 5.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4746) FNIP PF05725.12 GAM27826.1 - 2.8e-46 155.4 28.5 7.8e-07 29.2 0.3 10.0 6 3 4 10 10 10 10 FNIP Repeat bZIP_1 PF00170.21 GAM27826.1 - 0.00056 20.0 3.2 0.0012 18.9 3.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 GAM27826.1 - 0.0053 17.4 0.2 0.011 16.3 0.2 1.5 1 0 0 1 1 1 1 Initiation control protein YabA Cep57_MT_bd PF06657.13 GAM27826.1 - 0.0091 16.4 0.4 0.045 14.2 0.3 2.0 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 BLOC1_2 PF10046.9 GAM27826.1 - 0.018 15.3 0.4 0.04 14.2 0.4 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 GAM27826.1 - 0.037 13.8 0.5 0.075 12.8 0.5 1.4 1 0 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.11 GAM27826.1 - 0.23 11.9 1.9 0.48 10.9 1.9 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 GAM27826.1 - 0.36 10.9 4.3 0.8 9.8 4.3 1.6 1 0 0 1 1 1 0 Basic region leucine zipper ZapB PF06005.12 GAM27826.1 - 1.1 9.8 7.2 0.049 14.1 1.5 1.7 2 0 0 2 2 2 0 Cell division protein ZapB Tir_receptor_C PF07489.11 GAM27826.1 - 1.6 8.7 4.3 3.2 7.7 4.3 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Coiled PF05710.12 GAM27828.1 - 1.7e-07 31.9 6.0 1.9e-07 31.8 6.0 1.0 1 0 0 1 1 1 1 Coiled coil Pkinase_Tyr PF07714.17 GAM27829.1 - 1.7e-51 175.0 0.0 2.9e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM27829.1 - 8.9e-46 156.4 0.0 1.8e-45 155.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 GAM27829.1 - 2e-38 132.2 0.0 5.6e-27 94.8 0.0 2.7 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain LRR_8 PF13855.6 GAM27829.1 - 6.4e-25 86.7 26.9 2.4e-11 43.2 1.1 6.4 5 1 1 6 6 6 3 Leucine rich repeat Roc PF08477.13 GAM27829.1 - 8.1e-20 71.2 3.7 2e-16 60.3 0.0 3.0 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase LRR_4 PF12799.7 GAM27829.1 - 2.7e-15 56.2 32.6 3.9e-05 23.9 1.0 8.0 5 2 6 11 11 10 7 Leucine Rich repeats (2 copies) RhoGEF PF00621.20 GAM27829.1 - 8.2e-13 49.0 3.1 8.5e-12 45.7 1.7 2.8 2 0 0 2 2 2 1 RhoGEF domain Ras PF00071.22 GAM27829.1 - 1.1e-09 38.1 0.3 1.1e-07 31.6 0.0 2.6 2 0 0 2 2 2 1 Ras family SOG2 PF10428.9 GAM27829.1 - 1.6e-05 24.3 25.1 1.6e-05 24.3 25.1 5.8 5 1 1 6 6 4 1 RAM signalling pathway protein PH_13 PF16652.5 GAM27829.1 - 0.00053 19.8 0.8 0.00053 19.8 0.8 1.8 2 0 0 2 2 1 1 Pleckstrin homology domain LRR_1 PF00560.33 GAM27829.1 - 0.0022 18.3 21.1 4.1 8.3 0.0 9.6 9 1 0 9 9 9 1 Leucine Rich Repeat Gtr1_RagA PF04670.12 GAM27829.1 - 0.0029 17.0 0.1 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region LRR_9 PF14580.6 GAM27829.1 - 0.0049 16.4 13.3 3.5 7.1 0.5 5.5 3 1 2 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 GAM27829.1 - 0.6 10.3 35.1 0.47 10.6 0.1 9.8 11 0 0 11 11 11 0 Leucine Rich repeat DUF4423 PF14394.6 GAM27829.1 - 2.1 8.0 0.0 2.1 8.0 0.0 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4423) Complex1_LYR PF05347.15 GAM27830.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) FNIP PF05725.12 GAM27832.1 - 1.9e-41 139.9 13.4 1.4e-11 44.3 0.0 7.4 5 1 4 9 9 9 8 FNIP Repeat FtsJ PF01728.19 GAM27833.1 - 2.7e-63 213.2 0.0 3.7e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 GAM27833.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 GAM27833.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAM27833.1 - 0.16 12.7 0.1 0.56 11.0 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain DUF4667 PF15700.5 GAM27834.1 - 0.00059 20.0 3.3 0.00059 20.0 3.3 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4667) SR-25 PF10500.9 GAM27834.1 - 0.0082 15.8 6.7 0.0082 15.8 6.7 3.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 GAM27834.1 - 0.014 15.7 10.8 0.014 15.7 10.8 4.6 5 0 0 5 5 5 0 Early growth response N-terminal domain Rx_N PF18052.1 GAM27834.1 - 0.17 12.2 7.3 6.6 7.1 2.9 2.9 2 1 0 2 2 2 0 Rx N-terminal domain CCDC106 PF15794.5 GAM27834.1 - 1 9.0 10.4 4.1 7.0 2.1 3.7 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 106 PARG_cat PF05028.14 GAM27835.1 - 7.6e-129 429.8 0.0 1e-128 429.4 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) NUMOD3 PF07460.11 GAM27837.1 - 0.058 13.6 0.1 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) FNIP PF05725.12 GAM27838.1 - 0.0024 18.0 2.4 0.3 11.3 0.2 2.7 2 1 0 2 2 2 2 FNIP Repeat FNIP PF05725.12 GAM27839.1 - 2.5e-81 267.6 3.1 3.5e-13 49.5 0.0 9.2 6 2 0 9 9 9 8 FNIP Repeat Phosducin PF02114.16 GAM27840.1 - 0.034 13.1 0.0 0.038 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin HMG_box PF00505.19 GAM27841.1 - 4.2e-19 68.7 0.7 4.2e-19 68.7 0.7 2.1 2 0 0 2 2 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAM27841.1 - 2.7e-12 47.1 1.0 2.7e-12 47.1 1.0 2.2 2 1 0 2 2 1 1 HMG-box domain CHDNT PF08073.12 GAM27841.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 CHDNT (NUC034) domain DDHD PF02862.17 GAM27841.1 - 0.011 15.9 7.5 0.012 15.8 7.5 1.2 1 0 0 1 1 1 0 DDHD domain EloA-BP1 PF15870.5 GAM27841.1 - 0.014 15.7 5.9 0.021 15.1 5.9 1.2 1 0 0 1 1 1 0 ElonginA binding-protein 1 EPL1 PF10513.9 GAM27841.1 - 0.014 15.8 13.3 0.02 15.3 13.3 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Borrelia_P83 PF05262.11 GAM27841.1 - 0.016 13.7 9.3 0.02 13.4 9.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Plasmodium_Vir PF05795.11 GAM27841.1 - 0.027 13.9 1.5 0.029 13.8 1.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lin-8 PF03353.15 GAM27841.1 - 0.05 13.2 18.7 0.067 12.8 18.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MMR1 PF08505.10 GAM27841.1 - 0.065 13.5 14.1 0.081 13.2 14.1 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Phage_GPO PF05929.11 GAM27841.1 - 0.1 12.2 9.7 0.14 11.8 9.7 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Spt20 PF12090.8 GAM27841.1 - 0.11 12.0 32.3 0.18 11.4 32.3 1.3 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 GAM27841.1 - 0.15 10.8 15.0 0.18 10.5 15.0 1.1 1 0 0 1 1 1 0 Presenilin EIF4E-T PF10477.9 GAM27841.1 - 0.17 10.6 19.1 0.2 10.4 19.1 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E ALMT PF11744.8 GAM27841.1 - 0.21 10.4 7.5 0.22 10.3 7.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA_23 PF13476.6 GAM27841.1 - 0.3 11.5 12.6 0.37 11.3 12.6 1.1 1 0 0 1 1 1 0 AAA domain GREB1 PF15782.5 GAM27841.1 - 0.42 7.7 17.9 0.48 7.5 17.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PSI_PsaF PF02507.15 GAM27841.1 - 0.61 9.9 3.1 0.92 9.3 3.1 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III PAT1 PF09770.9 GAM27841.1 - 0.79 7.9 32.4 0.94 7.7 32.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.22 GAM27841.1 - 0.91 8.7 12.8 1.1 8.4 12.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter THOC2_N PF16134.5 GAM27841.1 - 1.1 7.8 11.1 1.5 7.3 11.1 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus SLC12 PF03522.15 GAM27841.1 - 1.2 8.1 12.6 1.5 7.8 12.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 GAM27841.1 - 1.2 9.1 11.8 1.8 8.5 11.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A AP1AR PF15745.5 GAM27841.1 - 1.3 8.6 14.3 1.8 8.2 14.3 1.1 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein RR_TM4-6 PF06459.12 GAM27841.1 - 1.3 8.8 19.1 1.8 8.3 19.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RskA PF10099.9 GAM27841.1 - 1.3 9.3 18.2 0.12 12.6 1.9 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA eIF-3_zeta PF05091.12 GAM27841.1 - 1.7 7.6 15.7 2 7.3 15.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 GAM27841.1 - 2.4 8.3 9.2 4.5 7.4 9.2 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.7 GAM27841.1 - 3.7 5.6 13.6 4 5.4 13.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 GAM27841.1 - 4.7 5.8 17.1 5.6 5.5 17.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.13 GAM27841.1 - 6.8 6.4 16.7 9.8 5.9 16.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AFT PF08731.11 GAM27841.1 - 9.2 6.7 12.6 39 4.7 12.6 2.1 1 1 0 1 1 1 0 Transcription factor AFT Myotub-related PF06602.14 GAM27843.1 - 1e-143 478.6 0.0 1e-143 478.6 0.0 2.0 3 0 0 3 3 3 1 Myotubularin-like phosphatase domain GRAM PF02893.20 GAM27843.1 - 0.0031 17.4 0.5 0.0031 17.4 0.5 2.0 2 0 0 2 2 2 1 GRAM domain 3-PAP PF12578.8 GAM27843.1 - 0.029 14.1 0.0 0.029 14.1 0.0 2.6 3 1 1 4 4 4 0 Myotubularin-associated protein Y_phosphatase PF00102.27 GAM27843.1 - 0.034 13.7 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SUIM_assoc PF16619.5 GAM27843.1 - 0.26 11.4 6.5 1.4 9.1 4.3 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CCDC53 PF10152.9 GAM27843.1 - 2.1 8.8 6.4 0.43 11.0 2.4 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Oxysterol_BP PF01237.18 GAM27844.1 - 1.7e-104 349.6 0.5 2.8e-104 348.9 0.5 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein DUF3484 PF11983.8 GAM27844.1 - 0.35 12.0 2.0 0.95 10.6 0.8 2.5 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch IF3_C PF00707.22 GAM27845.1 - 2.3e-06 27.5 0.3 9.7e-06 25.5 0.3 2.1 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 GAM27845.1 - 5.4e-06 26.6 0.2 1.9e-05 24.8 0.2 2.0 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain TFIIA PF03153.13 GAM27845.1 - 0.00062 19.9 32.7 0.00062 19.9 32.7 4.0 3 1 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit DUF5333 PF17267.2 GAM27846.1 - 0.041 14.1 0.8 0.041 14.1 0.8 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5333) Secretin_N_2 PF07655.13 GAM27846.1 - 4.8 7.8 11.0 9.3 6.9 11.0 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Helicase_C PF00271.31 GAM27847.1 - 8.1e-07 29.4 0.0 2.1e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM27848.1 - 3.9e-23 82.1 0.1 4e-22 78.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 GAM27848.1 - 0.00021 21.3 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TubC_N PF18563.1 GAM27848.1 - 0.15 12.1 0.0 1 9.4 0.1 2.5 2 1 0 2 2 2 0 TubC N-terminal docking domain SIR2 PF02146.17 GAM27849.1 - 1.9e-25 89.8 1.0 2e-19 70.2 0.7 2.3 1 1 1 2 2 2 2 Sir2 family Ribonuc_P_40 PF08584.11 GAM27849.1 - 0.063 12.6 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit MFS_1 PF07690.16 GAM27850.1 - 1.1e-30 106.8 27.9 1.1e-30 106.8 27.9 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF485 PF04341.12 GAM27850.1 - 0.17 11.9 16.1 0.11 12.4 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function, DUF485 TFIIA PF03153.13 GAM27853.1 - 0.0057 16.7 40.6 0.0057 16.7 40.6 2.0 2 0 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit Dapper PF15268.6 GAM27853.1 - 0.029 13.2 23.8 0.037 12.9 23.8 1.1 1 0 0 1 1 1 0 Dapper DUF2052 PF09747.9 GAM27853.1 - 0.049 13.7 40.2 0.48 10.5 4.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 GAM27853.1 - 0.077 12.7 0.1 0.077 12.7 0.1 3.4 3 1 1 4 4 1 0 FAM176 family Pex16 PF08610.10 GAM27853.1 - 0.15 11.2 6.1 0.11 11.7 3.6 1.7 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) CNDH2_C PF16858.5 GAM27853.1 - 0.19 11.6 28.2 0.2 11.5 21.7 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4746 PF15928.5 GAM27853.1 - 0.26 10.6 36.8 0.51 9.7 20.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) GAGA_bind PF06217.12 GAM27853.1 - 0.41 10.9 16.9 0.015 15.6 11.2 1.4 2 0 0 2 2 1 0 GAGA binding protein-like family DUF4638 PF15472.6 GAM27853.1 - 0.49 10.1 16.5 1.1 8.9 16.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Otopetrin PF03189.13 GAM27853.1 - 0.49 9.1 13.2 0.79 8.5 13.2 1.4 1 0 0 1 1 1 0 Otopetrin RR_TM4-6 PF06459.12 GAM27853.1 - 0.87 9.4 36.5 0.34 10.7 25.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.12 GAM27853.1 - 1.2 7.4 42.6 0.62 8.4 5.5 2.2 2 0 0 2 2 2 0 Mpp10 protein Ten_N PF06484.12 GAM27853.1 - 1.6 8.5 15.8 2.1 8.1 15.8 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region Mem_trans PF03547.18 GAM27853.1 - 2.1 6.6 3.4 2.9 6.2 3.4 1.4 1 0 0 1 1 1 0 Membrane transport protein FAM222A PF15258.6 GAM27853.1 - 2.5 7.1 34.5 3.6 6.6 34.5 1.1 1 0 0 1 1 1 0 Protein family of FAM222A SDA1 PF05285.12 GAM27853.1 - 3 7.2 34.8 0.58 9.5 17.2 2.2 2 0 0 2 2 2 0 SDA1 Neur_chan_memb PF02932.16 GAM27853.1 - 3.9 7.5 22.3 0.69 9.9 18.1 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Nop53 PF07767.11 GAM27853.1 - 4.1 6.7 42.5 5.3 6.3 7.4 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 GAM27853.1 - 4.3 5.5 36.7 0.76 8.0 23.3 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF4407 PF14362.6 GAM27853.1 - 6.3 6.0 17.3 9.9 5.4 17.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ndc1_Nup PF09531.10 GAM27853.1 - 6.8 5.3 8.7 7.6 5.1 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCSAP PF15748.5 GAM27853.1 - 7.2 6.7 36.0 0.96 9.6 26.9 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Isy1 PF06246.12 GAM27853.1 - 7.4 6.0 34.9 1.8e+04 -5.1 34.9 2.5 1 1 0 1 1 0 0 Isy1-like splicing family Membralin PF09746.9 GAM27853.1 - 7.8 5.4 14.3 12 4.8 14.3 1.3 1 0 0 1 1 1 0 Tumour-associated protein vATP-synt_E PF01991.18 GAM27856.1 - 0.026 14.0 0.3 0.034 13.6 0.3 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Pepsin-I3 PF06394.13 GAM27856.1 - 0.046 13.9 0.1 0.073 13.3 0.1 1.3 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain RRN3 PF05327.11 GAM27858.1 - 0.32 9.5 13.7 0.51 8.8 13.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 GAM27858.1 - 2.3 6.4 9.2 3.2 5.9 9.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAM27858.1 - 8.2 4.4 20.7 12 3.9 20.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi QSregVF_b PF12843.7 GAM27859.1 - 0.024 14.5 0.1 0.045 13.7 0.1 1.5 1 1 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Glyco_hydro_3 PF00933.21 GAM27860.1 - 2.4e-54 184.9 0.0 7.2e-53 180.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAM27860.1 - 5.4e-47 160.4 0.0 8.3e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 GAM27860.1 - 4.6e-10 39.5 0.0 8.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase_Tyr PF07714.17 GAM27861.1 - 1.8e-42 145.5 0.0 2.4e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM27861.1 - 1.5e-38 132.7 0.0 2.6e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 GAM27861.1 - 5.5e-07 29.6 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 GAM27861.1 - 6.8e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 GAM27861.1 - 0.0017 19.0 0.1 0.0042 17.8 0.1 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain FNIP PF05725.12 GAM27862.1 - 3.6e-74 244.7 15.9 1.3e-11 44.4 0.1 10.0 7 2 3 11 11 11 9 FNIP Repeat DUF1769 PF08588.10 GAM27862.1 - 0.00055 20.1 0.3 31 4.9 0.0 5.8 5 2 2 7 7 7 2 Protein of unknown function (DUF1769) DUF2207 PF09972.9 GAM27863.1 - 0.019 13.8 0.2 0.029 13.1 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 GAM27863.1 - 0.031 14.3 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Ccdc124 PF06244.12 GAM27864.1 - 1.2e-29 103.5 43.7 6.5e-25 88.2 43.7 2.8 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Ndc1_Nup PF09531.10 GAM27864.1 - 2.5 6.7 11.6 3.3 6.3 11.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup 2OG-FeII_Oxy_3 PF13640.6 GAM27865.1 - 2.3e-10 41.2 0.0 6.3e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 GAM27865.1 - 8.2e-05 21.9 0.0 0.00012 21.3 0.0 1.3 1 1 0 1 1 1 1 Poxvirus C4/C10 protein Neurochondrin PF05536.11 GAM27868.1 - 1.3e-21 76.6 5.5 9.9e-15 53.9 4.2 2.5 1 1 1 2 2 2 2 Neurochondrin DUF1799 PF08809.11 GAM27868.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) IBR PF01485.21 GAM27869.1 - 5.7e-18 64.9 23.5 8.1e-11 42.0 5.5 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 GAM27869.1 - 5.1e-05 23.0 3.1 5.1e-05 23.0 3.1 4.9 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM27869.1 - 0.00058 19.7 37.9 0.017 15.0 7.0 4.4 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM27869.1 - 0.0018 18.6 7.1 0.0018 18.6 7.1 4.4 3 2 2 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 GAM27869.1 - 0.0079 16.1 7.9 0.0079 16.1 7.9 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAM27869.1 - 0.018 14.8 3.1 0.068 12.9 3.1 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_14 PF17978.1 GAM27869.1 - 0.021 15.3 1.7 0.021 15.3 1.7 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Arm PF00514.23 GAM27870.1 - 3.6e-83 271.3 13.1 6.2e-12 45.1 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAM27870.1 - 1.4e-21 76.5 0.7 1.7e-06 28.4 0.1 5.0 4 1 0 4 4 4 4 HEAT-like repeat HEAT_2 PF13646.6 GAM27870.1 - 4.5e-16 59.0 0.6 2.3e-06 27.9 0.0 4.9 2 1 3 5 5 5 3 HEAT repeats Arm_3 PF16186.5 GAM27870.1 - 5.4e-15 54.7 0.4 1.7e-14 53.1 0.4 1.9 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 GAM27870.1 - 3.3e-12 45.6 0.9 0.0053 16.9 0.0 6.3 7 0 0 7 7 7 3 HEAT repeat IBB PF01749.20 GAM27870.1 - 1.4e-11 44.7 8.9 1.5e-08 35.0 6.6 2.9 1 1 1 2 2 2 2 Importin beta binding domain V-ATPase_H_C PF11698.8 GAM27870.1 - 1.5e-09 38.0 0.7 0.21 11.7 0.0 4.3 4 0 0 4 4 4 3 V-ATPase subunit H RICTOR_V PF14668.6 GAM27870.1 - 9.9e-06 25.7 0.9 3.2 8.1 0.0 4.7 4 1 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 GAM27870.1 - 2.3e-05 24.0 2.4 0.038 13.5 0.4 3.3 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 GAM27870.1 - 0.0002 20.1 0.2 0.0043 15.7 0.2 2.7 1 1 0 1 1 1 1 Adaptin N terminal region Atx10homo_assoc PF09759.9 GAM27870.1 - 0.00042 20.3 1.1 1.4 8.9 0.0 4.2 5 0 0 5 5 5 1 Spinocerebellar ataxia type 10 protein domain Mo25 PF08569.11 GAM27870.1 - 0.0031 16.9 0.1 0.025 14.0 0.0 2.2 1 1 1 2 2 2 1 Mo25-like HEAT_PBS PF03130.16 GAM27870.1 - 0.004 17.7 0.3 2 9.3 0.0 4.4 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat FAM220 PF15487.6 GAM27871.1 - 2.2 7.8 17.7 0.76 9.4 14.9 1.5 1 1 0 2 2 2 0 FAM220 family Trypan_PARP PF05887.11 GAM27871.1 - 2.3 8.2 31.9 1.2 9.1 26.1 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ndc1_Nup PF09531.10 GAM27871.1 - 2.4 6.8 9.3 3 6.4 9.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC27 PF09507.10 GAM27871.1 - 4.8 6.5 32.7 6.5 6.0 32.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 G-patch PF01585.23 GAM27872.1 - 2.1e-11 43.5 3.6 4.5e-11 42.4 3.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAM27872.1 - 3.7e-05 23.7 0.3 3.7e-05 23.7 0.3 2.3 2 1 0 2 2 2 1 G-patch domain CWC25 PF12542.8 GAM27872.1 - 0.055 14.4 9.1 0.12 13.3 9.1 1.4 1 1 0 1 1 1 0 Pre-mRNA splicing factor Ank_2 PF12796.7 GAM27873.1 - 2.6e-23 82.4 1.0 2.5e-10 40.8 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM27873.1 - 1e-19 70.3 1.5 4.1e-06 27.0 0.1 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM27873.1 - 6.9e-19 68.0 0.4 0.00047 20.7 0.0 4.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM27873.1 - 3.3e-14 51.6 3.0 0.097 13.3 0.0 7.1 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 GAM27873.1 - 5.7e-11 42.3 3.5 0.046 14.2 0.1 6.7 6 0 0 6 6 6 3 Ankyrin repeat DUF1293 PF06950.11 GAM27873.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) AAA PF00004.29 GAM27874.1 - 1.1e-38 132.6 0.0 2.4e-38 131.5 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAM27874.1 - 1.7e-28 98.4 0.0 3.3e-27 94.3 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 GAM27874.1 - 4.3e-21 74.8 8.1 4.3e-21 74.8 8.1 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 GAM27874.1 - 3.4e-09 36.4 0.0 1e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 GAM27874.1 - 3e-06 27.1 0.0 6.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAM27874.1 - 2.8e-05 24.6 0.1 0.00095 19.6 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 GAM27874.1 - 5.3e-05 22.5 0.0 0.0001 21.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 GAM27874.1 - 8.5e-05 21.9 0.0 0.00025 20.4 0.0 1.7 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 GAM27874.1 - 0.00011 22.5 2.7 0.045 14.0 0.0 2.8 2 1 1 3 3 2 2 AAA domain AAA_2 PF07724.14 GAM27874.1 - 0.00019 21.6 0.1 0.00095 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 GAM27874.1 - 0.00021 21.7 0.0 0.00072 19.9 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 GAM27874.1 - 0.00036 20.6 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAM27874.1 - 0.00041 20.3 0.0 0.001 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAM27874.1 - 0.00044 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Use1 PF09753.9 GAM27874.1 - 0.00097 18.9 3.2 0.0097 15.7 2.2 2.2 2 0 0 2 2 2 1 Membrane fusion protein Use1 AAA_18 PF13238.6 GAM27874.1 - 0.0038 17.8 0.2 0.019 15.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAM27874.1 - 0.0052 16.5 2.0 0.007 16.1 0.1 2.1 2 1 0 2 2 2 1 AAA domain Tma16 PF11176.8 GAM27874.1 - 0.0055 16.6 3.2 0.014 15.2 3.2 1.7 1 0 0 1 1 1 1 Translation machinery-associated protein 16 NACHT PF05729.12 GAM27874.1 - 0.0073 16.2 0.1 0.43 10.5 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_33 PF13671.6 GAM27874.1 - 0.015 15.4 0.0 0.055 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 GAM27874.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 GAM27874.1 - 0.027 13.9 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 GAM27874.1 - 0.034 13.2 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 GAM27874.1 - 0.035 14.5 0.0 0.085 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM27874.1 - 0.038 13.5 0.1 0.22 11.0 0.1 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 GAM27874.1 - 0.051 14.1 0.3 0.44 11.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Torsin PF06309.11 GAM27874.1 - 0.053 13.6 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Torsin TniB PF05621.11 GAM27874.1 - 0.054 12.9 0.4 14 5.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein AAA_25 PF13481.6 GAM27874.1 - 0.065 12.8 0.1 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 GAM27874.1 - 0.074 12.3 0.1 4.8 6.3 0.1 2.4 1 1 0 2 2 2 0 KAP family P-loop domain PhoH PF02562.16 GAM27874.1 - 0.077 12.4 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 GAM27874.1 - 0.084 12.6 0.0 0.3 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 GAM27874.1 - 0.11 12.3 0.0 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF630 PF04783.12 GAM27874.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF630) ATPase PF06745.13 GAM27874.1 - 0.19 11.1 2.6 7.3 5.9 0.0 2.5 2 1 1 3 3 2 0 KaiC ATPase_2 PF01637.18 GAM27874.1 - 0.43 10.5 5.8 1.9 8.4 0.0 2.9 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea TP53IP5 PF15331.6 GAM27874.1 - 0.59 10.2 5.8 6.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 WD40 PF00400.32 GAM27875.1 - 1.9e-40 136.1 41.3 1.1e-06 29.2 0.8 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM27875.1 - 8.1e-17 61.3 11.0 0.002 18.4 0.0 6.6 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM27875.1 - 5.4e-11 41.8 17.4 0.06 12.0 0.2 6.3 4 1 2 6 6 6 6 Nucleoporin Nup120/160 F-box-like PF12937.7 GAM27875.1 - 1.2e-08 34.7 0.1 3.2e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 GAM27875.1 - 2.6e-07 30.3 0.1 3.3e-05 23.4 0.1 2.6 2 0 0 2 2 2 1 WD40-like domain F-box PF00646.33 GAM27875.1 - 6e-07 29.2 1.0 1.2e-06 28.2 1.0 1.6 1 0 0 1 1 1 1 F-box domain DUF5046 PF16465.5 GAM27875.1 - 0.011 15.2 0.0 4.6 6.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5046) PQQ_2 PF13360.6 GAM27875.1 - 0.011 15.3 0.3 1.8 8.1 0.0 2.6 1 1 2 3 3 3 0 PQQ-like domain PI3K_P85_iSH2 PF16454.5 GAM27875.1 - 0.11 12.1 1.7 0.19 11.3 1.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AMP-binding PF00501.28 GAM27876.1 - 1.8e-96 323.3 0.0 2.3e-96 323.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM27876.1 - 0.0098 16.8 0.0 0.024 15.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CAP_N PF01213.19 GAM27876.1 - 0.19 11.2 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-RING_2 PF13639.6 GAM27878.1 - 2.6e-10 40.5 4.3 6e-10 39.3 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 GAM27878.1 - 2.3e-06 27.6 2.9 2.3e-06 27.6 2.9 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GAM27878.1 - 2.3e-06 27.3 3.8 5.4e-06 26.2 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAM27878.1 - 4e-06 26.8 1.3 1.4e-05 25.0 1.3 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 GAM27878.1 - 1.1e-05 25.1 4.6 2.4e-05 24.1 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM27878.1 - 2.8e-05 24.3 4.1 9.4e-05 22.6 4.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAM27878.1 - 4.1e-05 23.5 5.2 0.00011 22.1 5.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAM27878.1 - 0.00014 21.7 3.0 0.00026 20.8 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM27878.1 - 0.0011 18.9 5.3 0.002 18.0 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 GAM27878.1 - 0.002 18.3 5.1 0.0068 16.6 5.1 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 GAM27878.1 - 0.0053 16.6 3.2 0.013 15.3 3.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 GAM27878.1 - 0.029 14.1 2.4 0.064 13.0 2.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 GAM27878.1 - 0.036 13.7 4.2 0.083 12.5 4.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 GAM27878.1 - 0.21 11.4 3.1 0.66 9.8 3.1 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF5528 PF17666.1 GAM27878.1 - 0.35 10.8 5.2 0.35 10.8 0.8 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5528) FYVE PF01363.21 GAM27878.1 - 0.38 10.9 2.8 0.82 9.9 2.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger NAP PF00956.18 GAM27879.1 - 1.1e-09 38.0 29.9 1.9e-06 27.3 29.9 4.2 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) MCM_bind PF09739.9 GAM27879.1 - 0.031 12.7 9.2 0.038 12.4 9.2 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Med13_C PF06333.12 GAM27879.1 - 0.091 12.0 9.3 0.11 11.8 9.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Ndc1_Nup PF09531.10 GAM27879.1 - 0.51 9.0 8.4 0.58 8.8 8.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CEP19 PF14933.6 GAM27879.1 - 0.73 10.1 16.1 1.1 9.6 16.1 1.3 1 0 0 1 1 1 0 CEP19-like protein DUF908 PF06012.12 GAM27879.1 - 0.84 9.0 12.6 0.98 8.8 12.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) HNF-1_N PF04814.13 GAM27879.1 - 0.93 10.1 15.5 1.4 9.5 15.5 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus GREB1 PF15782.5 GAM27879.1 - 1.4 6.0 12.3 1.5 5.9 12.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAM76 PF16046.5 GAM27879.1 - 3.5 6.9 16.8 13 5.0 16.4 1.8 2 0 0 2 2 2 0 FAM76 protein PPL5 PF18168.1 GAM27879.1 - 4.9 6.3 10.2 7.2 5.8 10.2 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Suf PF05843.14 GAM27879.1 - 5.1 7.0 14.7 7.4 6.5 14.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 GAM27879.1 - 6.2 6.8 10.4 8.3 6.4 10.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ABC1 PF03109.16 GAM27880.1 - 3.8e-33 114.2 1.9 6.2e-33 113.5 0.0 2.5 2 0 0 2 2 2 1 ABC1 family SUIM_assoc PF16619.5 GAM27880.1 - 3.1 7.9 0.0 3.1 7.9 0.0 11.3 5 3 2 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 LIM PF00412.22 GAM27881.1 - 4.1e-28 97.4 60.6 1.4e-10 41.2 2.2 5.7 5 1 1 6 6 6 4 LIM domain PTEN_C2 PF10409.9 GAM27881.1 - 4.4e-18 65.3 0.6 9.7e-18 64.2 0.6 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 GAM27881.1 - 8.6e-07 28.8 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAM27881.1 - 0.00034 20.2 0.0 0.00065 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAM27881.1 - 0.0077 16.2 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Stc1 PF12898.7 GAM27881.1 - 0.0087 16.6 2.2 0.0087 16.6 2.2 4.8 2 1 2 4 4 4 2 Stc1 domain PTPlike_phytase PF14566.6 GAM27881.1 - 0.03 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_L37e PF01907.19 GAM27882.1 - 1.3e-26 92.5 11.0 2.1e-26 91.8 11.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 GAM27882.1 - 0.00044 20.3 0.9 0.00061 19.9 0.9 1.3 1 1 0 1 1 1 1 SelR domain DZR PF12773.7 GAM27882.1 - 0.02 14.9 1.5 0.031 14.3 1.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-CCCH PF00642.24 GAM27884.1 - 1.8e-19 69.1 14.9 1.6e-10 40.6 2.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAM27884.1 - 5.2e-11 42.1 11.5 4e-06 26.5 1.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAM27884.1 - 8.3e-11 41.6 14.8 3.5e-06 26.9 3.0 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 GAM27884.1 - 0.0023 18.4 11.2 0.074 13.6 0.9 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 GAM27884.1 - 0.0037 17.9 0.7 0.0037 17.9 0.7 3.4 2 1 1 3 3 3 2 Torus domain TFIIA PF03153.13 GAM27884.1 - 0.024 14.7 46.2 0.079 13.0 12.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rbc25 PF08292.12 GAM27884.1 - 0.027 14.7 1.8 0.027 14.7 1.8 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Usp PF00582.26 GAM27884.1 - 2 9.0 4.2 0.46 11.0 0.6 1.7 2 1 0 2 2 2 0 Universal stress protein family Lustrin_cystein PF14625.6 GAM27884.1 - 3 8.3 7.7 12 6.4 1.8 2.7 1 1 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Connexin PF00029.19 GAM27884.1 - 5 6.8 7.5 0.55 10.0 1.0 2.1 2 0 0 2 2 2 0 Connexin Kelch_1 PF01344.25 GAM27885.1 - 5.4e-30 102.7 13.0 9.8e-13 47.5 0.1 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 GAM27885.1 - 1.9e-25 88.2 2.7 8.7e-10 38.5 0.1 4.2 2 1 2 4 4 4 3 Kelch motif BTB_2 PF02214.22 GAM27885.1 - 3.6e-17 62.5 0.0 8.1e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.6 GAM27885.1 - 7.8e-13 48.2 0.1 0.00096 19.1 0.0 3.7 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM27885.1 - 1.8e-09 37.2 2.8 0.0018 18.1 0.0 5.0 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.6 GAM27885.1 - 1.1e-08 35.2 6.0 0.032 14.5 0.0 4.8 5 0 0 5 5 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM27885.1 - 6.1e-07 29.3 0.1 0.023 14.7 0.0 2.8 2 0 0 2 2 2 2 Kelch motif BTB_3 PF16017.5 GAM27885.1 - 0.00012 22.2 0.0 0.00027 21.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain CBM65_1 PF18259.1 GAM27885.1 - 0.0017 18.5 0.0 0.042 14.0 0.0 2.3 2 0 0 2 2 2 1 Carbohydrate binding module 65 domain 1 IFP_35_N PF07334.13 GAM27885.1 - 0.045 13.8 0.2 0.14 12.3 0.2 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Tup_N PF08581.10 GAM27885.1 - 0.05 13.9 4.1 0.095 13.0 4.1 1.4 1 0 0 1 1 1 0 Tup N-terminal Fib_alpha PF08702.10 GAM27885.1 - 0.059 13.5 0.8 0.14 12.4 0.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RhoGEF PF00621.20 GAM27886.1 - 5.1e-35 121.4 4.8 5.1e-35 121.4 4.8 2.0 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 GAM27886.1 - 9.9e-32 109.4 0.9 1.1e-14 54.5 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain IQ PF00612.27 GAM27886.1 - 5.8e-05 22.5 2.3 0.00016 21.2 2.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH_13 PF16652.5 GAM27886.1 - 6.1e-05 22.9 2.9 0.00019 21.3 2.9 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 GAM27886.1 - 0.0009 19.2 1.8 0.0009 19.2 1.8 2.4 2 0 0 2 2 2 1 PH domain CAMSAP_CH PF11971.8 GAM27886.1 - 0.0013 18.6 0.6 0.17 11.7 0.1 3.2 3 0 0 3 3 3 1 CAMSAP CH domain PH_10 PF15411.6 GAM27886.1 - 0.018 15.3 0.7 0.018 15.3 0.7 2.2 2 0 0 2 2 1 0 Pleckstrin homology domain CH_2 PF06294.11 GAM27886.1 - 0.027 14.6 0.2 10 6.3 0.0 3.4 3 0 0 3 3 3 0 CH-like domain in sperm protein PH_16 PF17838.1 GAM27886.1 - 0.062 13.1 0.9 0.21 11.5 0.9 1.9 1 1 0 1 1 1 0 PH domain PH PF00169.29 GAM27886.1 - 0.17 12.4 6.2 1.3 9.6 6.3 2.3 1 1 0 1 1 1 0 PH domain Baculo_PEP_C PF04513.12 GAM27886.1 - 3.2 7.8 13.2 2.2 8.3 1.3 2.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TFIIA PF03153.13 GAM27886.1 - 9.7 6.1 12.9 17 5.3 12.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cyt-b5 PF00173.28 GAM27888.1 - 4.2e-21 74.9 0.3 6e-21 74.4 0.3 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CDK2AP PF09806.9 GAM27888.1 - 1.1 9.3 9.8 0.19 11.8 0.4 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein ANF_receptor PF01094.28 GAM27888.1 - 2.5 7.1 7.1 3.6 6.6 0.8 2.0 2 0 0 2 2 2 0 Receptor family ligand binding region Tetraspanin PF00335.20 GAM27889.1 - 9.9e-06 25.4 14.4 9.9e-06 25.4 14.4 1.8 1 1 1 2 2 2 1 Tetraspanin family TssN PF17555.2 GAM27889.1 - 0.003 17.0 13.0 0.0039 16.6 13.0 1.2 1 0 0 1 1 1 1 Type VI secretion system, TssN CD20 PF04103.15 GAM27889.1 - 0.0063 16.6 11.1 0.0079 16.3 11.1 1.3 1 0 0 1 1 1 1 CD20-like family RapH_N PF18801.1 GAM27889.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal SLC3A2_N PF16028.5 GAM27889.1 - 0.31 10.6 4.8 8.1 6.1 2.9 2.5 2 1 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus DUF2981 PF11200.8 GAM27889.1 - 0.59 9.8 4.2 0.76 9.5 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Insulin_TMD PF17870.1 GAM27889.1 - 0.83 9.8 7.3 0.28 11.3 1.9 2.7 2 1 1 3 3 3 0 Insulin receptor trans-membrane segment ABC2_membrane_5 PF13346.6 GAM27889.1 - 1.1 8.7 20.2 0.61 9.6 18.0 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein MTABC_N PF16185.5 GAM27889.1 - 1.3 8.5 8.4 1 8.8 6.9 1.5 1 1 1 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region ABC2_membrane_2 PF12679.7 GAM27889.1 - 2.8 7.1 10.3 3.2 7.0 10.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2070 PF09843.9 GAM27889.1 - 2.9 6.1 10.2 3.2 5.9 10.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Holin_SPP1 PF04688.13 GAM27889.1 - 3 8.1 8.8 0.23 11.7 0.7 2.7 2 1 1 3 3 3 0 SPP1 phage holin Arteri_Gl PF00951.18 GAM27889.1 - 4.8 6.9 9.8 0.28 11.0 2.8 2.1 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein RDD PF06271.12 GAM27889.1 - 5.1 7.3 13.3 12 6.1 0.7 2.2 1 1 1 2 2 2 0 RDD family SLATT_5 PF18160.1 GAM27889.1 - 6.7 6.0 10.7 1.3 8.3 5.5 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 EF-hand_4 PF12763.7 GAM27890.1 - 5.5e-37 125.9 6.2 4.2e-15 55.6 0.0 4.4 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 GAM27890.1 - 0.00013 21.3 14.7 8.8 6.1 0.5 5.8 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 GAM27890.1 - 0.12 12.8 13.3 0.57 10.7 0.2 4.2 4 1 0 4 4 4 0 EF-hand domain pair Spc7 PF08317.11 GAM27890.1 - 0.45 9.3 42.2 0.071 12.0 25.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein EF-hand_6 PF13405.6 GAM27890.1 - 1.8 8.7 22.7 4.1 7.6 0.0 6.2 6 0 0 6 6 6 0 EF-hand domain HAP1_N PF04849.13 GAM27890.1 - 6.6 5.8 35.7 10 5.2 35.7 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FlaC_arch PF05377.11 GAM27890.1 - 7.8 7.0 6.9 3.5 8.1 1.2 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 GAM27890.1 - 7.8 6.5 29.7 1.1 9.2 4.9 3.2 1 1 2 3 3 3 0 Laminin Domain II DUF4834 PF16118.5 GAM27891.1 - 0.66 11.0 3.0 18 6.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) S36_mt PF10937.8 GAM27891.1 - 0.67 11.6 9.5 1.1 10.9 2.0 3.3 1 1 2 3 3 3 0 Ribosomal protein S36, mitochondrial CENP-B_dimeris PF09026.10 GAM27891.1 - 3.7 8.0 22.6 1.2 9.6 1.5 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Meth_synt_2 PF01717.18 GAM27892.1 - 1.9e-07 30.7 0.0 5.1e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain SYF2 PF08231.12 GAM27892.1 - 0.23 11.9 0.1 0.58 10.5 0.0 1.7 3 0 0 3 3 3 0 SYF2 splicing factor PI3_PI4_kinase PF00454.27 GAM27893.1 - 1.3e-55 189.0 0.0 3.5e-55 187.5 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 GAM27893.1 - 6.1e-35 121.0 0.7 1.2e-34 120.1 0.7 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.13 GAM27893.1 - 1.3e-17 63.6 0.4 1.4e-16 60.3 0.0 3.2 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 GAM27893.1 - 1.1e-13 50.7 0.1 2.7e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 GAM27893.1 - 0.071 13.4 0.0 35 5.0 0.0 3.9 2 0 0 2 2 2 0 HEAT repeat Integrase_H2C2 PF17921.1 GAM27894.1 - 9.8e-12 44.8 0.8 1.9e-11 43.9 0.8 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 GAM27894.1 - 0.038 14.2 0.1 0.08 13.2 0.1 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Aida_N PF08910.10 GAM27894.1 - 0.15 12.5 2.2 0.16 12.4 0.7 1.8 2 0 0 2 2 2 0 Aida N-terminus TPR_2 PF07719.17 GAM27895.1 - 3.9e-05 23.5 3.6 0.047 13.8 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM27895.1 - 0.00012 22.3 0.3 0.091 13.1 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM27895.1 - 0.011 15.5 3.1 6.6 6.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM27895.1 - 0.033 14.1 0.2 1.7 8.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat CAP_N PF01213.19 GAM27895.1 - 1.4 8.4 6.5 3.4 7.1 6.5 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_39 PF01229.17 GAM27896.1 - 0.0084 14.8 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 DUF3557 PF12078.8 GAM27897.1 - 0.013 15.5 1.1 0.91 9.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3557) DUF92 PF01940.16 GAM27898.1 - 2.2e-81 272.8 2.7 2.6e-81 272.5 2.7 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF4199 PF13858.6 GAM27898.1 - 0.01 16.2 3.8 0.019 15.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) TctA PF01970.16 GAM27898.1 - 0.2 10.4 9.0 1.2 7.7 2.3 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family DUF3899 PF13038.6 GAM27898.1 - 0.8 10.3 6.0 8.8 6.9 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) PhoLip_ATPase_C PF16212.5 GAM27899.1 - 2.1e-66 224.3 26.1 2.1e-66 224.3 26.1 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM27899.1 - 1.8e-15 56.4 3.1 5.7e-15 54.8 3.1 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAM27899.1 - 6.8e-11 42.1 0.0 1.6e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM27899.1 - 7.7e-10 39.4 0.0 0.00036 20.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAM27899.1 - 0.00041 19.9 0.1 0.00041 19.9 0.1 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAM27899.1 - 0.0038 17.0 0.4 0.02 14.6 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LMF1 PF06762.14 GAM27900.1 - 0.075 12.1 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Lipase maturation factor TPR_2 PF07719.17 GAM27901.1 - 1e-17 62.7 0.3 0.00018 21.3 0.1 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAM27901.1 - 6.9e-15 54.2 0.5 0.0028 17.4 0.1 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM27901.1 - 1.1e-10 41.4 0.1 0.1 13.5 0.0 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM27901.1 - 5.8e-10 38.7 0.0 0.00015 21.4 0.0 3.5 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 GAM27901.1 - 1.8e-09 37.1 0.7 0.58 10.5 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM27901.1 - 1.5e-08 34.4 0.9 0.0016 18.7 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM27901.1 - 1.9e-08 34.5 1.4 0.18 12.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAM27901.1 - 1.9e-08 34.8 0.0 0.0099 16.5 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM27901.1 - 7.7e-08 32.4 0.0 2.1e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAM27901.1 - 6.4e-07 29.0 4.5 0.11 12.4 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAM27901.1 - 1.9e-05 25.1 0.0 0.012 16.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM27901.1 - 3.1e-05 23.7 0.8 0.068 13.2 0.0 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM27901.1 - 8.8e-05 21.8 0.2 1.3 8.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.9 GAM27901.1 - 0.028 14.1 2.6 0.47 10.2 1.0 3.3 2 1 1 3 3 3 0 26S proteasome subunit RPN7 DUF4812 PF16071.5 GAM27901.1 - 0.072 12.9 0.1 0.96 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4812) tRNA-synt_1 PF00133.22 GAM27902.1 - 3e-178 593.8 0.1 4.6e-178 593.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM27902.1 - 1.1e-24 87.1 0.2 2e-24 86.3 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM27902.1 - 2.3e-21 76.0 5.7 7e-16 58.0 0.0 3.5 4 0 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAM27902.1 - 0.00011 21.8 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAM27902.1 - 0.0014 18.0 0.0 0.56 9.5 0.0 3.1 2 1 1 3 3 3 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 GAM27902.1 - 3.3 7.7 7.9 11 6.0 7.9 1.9 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS CHORD PF04968.12 GAM27903.1 - 0.1 13.4 0.3 0.23 12.2 0.3 1.5 1 0 0 1 1 1 0 CHORD SUR7 PF06687.12 GAM27903.1 - 0.12 12.0 2.3 0.2 11.3 2.3 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF3533 PF12051.8 GAM27903.1 - 0.53 9.2 5.5 0.91 8.4 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TFIIA PF03153.13 GAM27903.1 - 1.2 9.1 18.7 1.3 8.9 18.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_6 PF13516.6 GAM27904.1 - 6.3e-15 53.9 11.8 8.3e-05 22.3 0.1 5.4 5 0 0 5 5 5 4 Leucine Rich repeat F-box-like PF12937.7 GAM27904.1 - 2.7e-05 24.0 0.0 4.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAM27904.1 - 0.0047 17.3 4.3 4.5 7.8 0.3 4.6 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.33 GAM27904.1 - 0.036 14.0 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 F-box domain PilN PF05137.13 GAM27904.1 - 0.12 12.6 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) Vinculin PF01044.19 GAM27905.1 - 3.2e-41 141.6 50.5 1.1e-21 76.9 23.6 4.8 1 1 3 4 4 4 4 Vinculin family I_LWEQ PF01608.17 GAM27905.1 - 0.0025 18.1 39.5 0.0031 17.8 4.7 6.2 5 1 1 6 6 6 2 I/LWEQ domain LcrG PF07216.12 GAM27905.1 - 0.0085 16.0 5.6 1.3 9.0 0.1 3.5 3 0 0 3 3 3 2 LcrG protein P53_C PF11619.8 GAM27905.1 - 0.05 13.7 9.7 2.8 8.1 0.3 4.8 3 2 0 3 3 3 0 Transcription factor P53 - C terminal domain NTP_transf_4 PF13562.6 GAM27905.1 - 0.12 12.6 0.9 0.87 9.8 0.2 2.6 2 0 0 2 2 2 0 Sugar nucleotidyl transferase DUF5352 PF17303.2 GAM27905.1 - 0.9 9.4 3.0 11 5.8 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5352) DASH_Dad1 PF08649.10 GAM27905.1 - 1.8 8.8 5.1 40 4.5 0.0 4.5 4 0 0 4 4 4 0 DASH complex subunit Dad1 DUF4484 PF14831.6 GAM27905.1 - 5.1 7.1 14.7 0.2 11.6 0.7 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4484) OCD_Mu_crystall PF02423.15 GAM27906.1 - 2.4e-56 191.0 1.7 2.7e-56 190.8 1.7 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 GAM27906.1 - 1.3e-07 31.8 0.2 3.2e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 GAM27906.1 - 0.00012 21.4 0.2 0.00038 19.8 0.2 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Dabb PF07876.12 GAM27907.1 - 1.7e-15 57.4 0.0 1.8e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Flt3_lig PF02947.14 GAM27908.1 - 0.14 12.3 2.4 3.4 7.9 0.1 2.7 3 0 0 3 3 3 0 flt3 ligand SET PF00856.28 GAM27909.1 - 5.5e-21 75.7 0.1 2.1e-20 73.8 0.0 2.0 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 GAM27909.1 - 1.2e-12 48.4 4.4 1.2e-12 48.4 4.4 2.2 2 0 0 2 2 2 1 Pre-SET motif DUF3123 PF11321.8 GAM27909.1 - 2.9 8.6 5.7 4.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) DDE_Tnp_4 PF13359.6 GAM27910.1 - 5e-12 45.8 0.4 2.3e-10 40.4 0.2 2.5 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM27910.1 - 0.0002 21.1 3.0 0.00041 20.1 3.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Dicty_REP PF05086.12 GAM27911.1 - 5 5.0 6.4 7.6 4.4 6.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M48 PF01435.18 GAM27912.1 - 3.2e-26 92.3 0.1 9.1e-26 90.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M48_N PF16491.5 GAM27912.1 - 7.9e-19 68.2 8.7 7.9e-19 68.2 8.7 2.0 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M56 PF05569.11 GAM27912.1 - 0.00053 19.3 0.2 0.0013 18.0 0.3 1.6 2 0 0 2 2 2 1 BlaR1 peptidase M56 DCX PF03607.17 GAM27912.1 - 0.00084 19.4 0.5 0.0079 16.3 0.0 2.8 3 0 0 3 3 3 1 Doublecortin FNIP PF05725.12 GAM27913.1 - 1.3e-53 178.9 11.1 1.1e-16 60.7 0.2 5.2 4 1 1 5 5 5 5 FNIP Repeat Glyco_hydro_65C PF03633.15 GAM27913.1 - 0.022 14.7 0.4 7.8 6.5 0.0 4.2 5 0 0 5 5 5 0 Glycosyl hydrolase family 65, C-terminal domain FNIP PF05725.12 GAM27914.1 - 1.7e-19 69.7 0.2 2.9e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 FNIP Repeat Pkinase PF00069.25 GAM27914.1 - 5.2e-19 68.6 0.2 1.4e-18 67.3 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27914.1 - 9.3e-09 34.9 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1987 PF09345.10 GAM27914.1 - 0.07 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) DUF1942 PF09167.11 GAM27914.1 - 0.1 12.5 0.1 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1942) Kinase-like PF14531.6 GAM27914.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HA2 PF04408.23 GAM27915.1 - 1.5e-19 70.3 0.0 1.5e-19 70.3 0.0 4.2 5 0 0 5 5 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAM27915.1 - 4e-14 52.7 0.0 9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAM27915.1 - 2.9e-13 50.1 0.0 7.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAM27915.1 - 2.8e-08 33.7 0.1 5.9e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 GAM27915.1 - 4.7e-05 23.2 0.1 9.2e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAM27915.1 - 6.2e-05 23.4 0.2 0.00016 22.1 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAM27915.1 - 8.7e-05 22.8 0.1 0.00019 21.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain TLP-20 PF06088.11 GAM27915.1 - 0.011 15.7 0.1 0.011 15.7 0.1 4.5 4 1 0 4 4 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Flavi_DEAD PF07652.14 GAM27915.1 - 0.013 15.5 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain SRP54 PF00448.22 GAM27915.1 - 0.02 14.5 0.7 0.045 13.4 0.7 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 GAM27915.1 - 0.02 14.2 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 GAM27915.1 - 0.022 15.3 0.0 0.11 13.0 0.0 2.2 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 GAM27915.1 - 0.038 13.1 0.0 0.086 11.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 GAM27915.1 - 0.12 12.8 0.1 0.12 12.8 0.1 4.6 3 1 0 4 4 2 0 AAA domain AAA_14 PF13173.6 GAM27915.1 - 0.13 12.3 0.4 1.1 9.3 0.4 2.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAM27915.1 - 4.8 7.3 8.4 0.51 10.5 0.0 3.6 3 1 0 4 4 3 0 AAA domain OB_NTP_bind PF07717.16 GAM27916.1 - 3.4e-23 81.8 0.1 8.8e-23 80.5 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GAM27916.1 - 8.8e-23 80.6 0.0 8.8e-23 80.6 0.0 4.1 2 1 1 3 3 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAM27916.1 - 2.5e-12 47.1 0.0 6.5e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAM27916.1 - 9.9e-06 25.9 0.0 4e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 GAM27916.1 - 2.5e-05 24.1 0.0 9.5e-05 22.2 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 GAM27916.1 - 0.0015 18.9 0.0 0.0052 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAM27916.1 - 0.0018 17.4 0.0 0.0049 16.0 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein PWI PF01480.17 GAM27916.1 - 0.0024 18.1 0.0 0.008 16.5 0.0 1.9 1 0 0 1 1 1 1 PWI domain Flavi_DEAD PF07652.14 GAM27916.1 - 0.0042 17.1 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.22 GAM27916.1 - 0.029 14.0 0.2 0.22 11.1 0.1 2.6 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 GAM27916.1 - 0.21 12.0 0.0 0.21 12.0 0.0 2.5 2 1 0 2 2 1 0 AAA ATPase domain AAA_23 PF13476.6 GAM27916.1 - 0.22 12.0 0.0 0.22 12.0 0.0 4.4 2 1 2 4 4 3 0 AAA domain CLN5 PF15014.6 GAM27917.1 - 6.4e-21 75.3 10.4 1e-20 74.6 10.4 1.3 1 1 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 ATG27 PF09451.10 GAM27917.1 - 2.9e-10 40.5 0.0 4.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 GAM27917.1 - 2.6e-05 23.4 0.0 4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor PRIMA1 PF16101.5 GAM27917.1 - 0.98 9.5 5.3 0.14 12.2 0.6 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 ERM PF00769.19 GAM27918.1 - 0.0087 15.9 11.4 0.0087 15.9 11.4 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Tht1 PF04163.12 GAM27918.1 - 0.024 13.4 6.3 0.035 12.9 6.3 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein RTBV_P46 PF06216.11 GAM27918.1 - 0.041 12.8 0.9 0.054 12.4 0.9 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein NBP1 PF08537.10 GAM27918.1 - 0.085 12.3 19.8 0.13 11.6 12.9 2.4 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 PKcGMP_CC PF16808.5 GAM27918.1 - 0.15 11.9 0.1 0.15 11.9 0.1 5.0 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATP-synt_E_2 PF08112.11 GAM27918.1 - 0.23 11.7 6.2 5.5 7.3 0.4 3.2 3 0 0 3 3 3 0 ATP synthase epsilon subunit YabA PF06156.13 GAM27918.1 - 0.41 11.3 19.6 0.07 13.8 3.1 3.3 1 1 2 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 GAM27918.1 - 0.46 10.9 22.5 0.056 13.9 14.0 2.2 1 1 1 2 2 2 0 Fez1 Csm1_N PF18504.1 GAM27918.1 - 0.48 10.8 26.3 0.45 10.9 3.7 4.6 2 1 1 4 4 4 0 Csm1 N-terminal domain Spc7 PF08317.11 GAM27918.1 - 0.5 9.2 26.2 0.14 11.1 17.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 GAM27918.1 - 0.81 9.8 27.4 18 5.3 13.5 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2046 PF09755.9 GAM27918.1 - 0.97 8.6 22.5 3.4 6.8 22.6 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) HOOK PF05622.12 GAM27918.1 - 2.1 6.4 28.9 0.54 8.3 19.2 2.1 1 1 1 2 2 2 0 HOOK protein ATG16 PF08614.11 GAM27918.1 - 3.1 8.0 28.8 3.6 7.7 15.1 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 GAM27918.1 - 3.2 7.8 29.6 3.5 7.7 10.8 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Sec34 PF04136.15 GAM27918.1 - 3.6 7.4 15.4 2.6 7.9 6.0 2.4 1 1 1 2 2 2 0 Sec34-like family ZapB PF06005.12 GAM27918.1 - 4.3 7.9 31.6 84 3.7 16.8 3.8 1 1 1 2 2 2 0 Cell division protein ZapB GAS PF13851.6 GAM27918.1 - 4.7 6.5 25.5 19 4.5 25.2 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding SOGA PF11365.8 GAM27918.1 - 5.1 8.3 17.4 3.8 8.7 6.2 2.8 1 1 1 2 2 2 0 Protein SOGA CENP-F_leu_zip PF10473.9 GAM27918.1 - 6.5 6.8 28.2 0.8 9.7 8.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 VPS11_C PF12451.8 GAM27918.1 - 7.2 6.9 6.2 7.4 6.9 0.7 3.0 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Itfg2 PF15907.5 GAM27919.1 - 1.5e-65 221.4 0.6 3.8e-33 115.0 0.0 3.3 3 1 0 3 3 3 3 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 GAM27919.1 - 2.7e-10 40.2 1.0 0.0022 18.0 0.1 3.7 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 GAM27919.1 - 2.4e-07 31.2 1.4 0.027 15.1 0.3 3.5 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAM27919.1 - 2.8e-07 30.6 2.7 0.02 15.0 0.2 3.0 2 0 0 2 2 2 2 FG-GAP repeat BBS1 PF14779.6 GAM27919.1 - 2.5e-06 27.2 0.0 0.0078 15.7 0.0 2.6 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.6 GAM27919.1 - 0.00012 21.6 0.9 0.0015 17.9 0.2 2.8 2 1 1 3 3 3 2 PTHB1 N-terminus BBS2_C PF14782.6 GAM27919.1 - 0.0092 14.8 0.8 2.1 7.0 0.1 3.0 1 1 2 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal PliI PF16743.5 GAM27919.1 - 0.068 12.9 1.8 0.91 9.3 0.1 2.9 2 1 1 3 3 3 0 Periplasmic lysozyme inhibitor of I-type lysozyme FKBP_C PF00254.28 GAM27921.1 - 7e-32 109.6 0.0 7.7e-32 109.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4394 PF14339.6 GAM27922.1 - 0.0022 17.4 4.4 0.031 13.7 0.0 3.4 1 1 2 4 4 4 2 Domain of unknown function (DUF4394) GDPD PF03009.17 GAM27923.1 - 2.9e-56 191.1 0.0 5.8e-56 190.1 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 GAM27923.1 - 1.2e-53 179.7 10.5 2.4e-13 50.5 0.0 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM27923.1 - 9.2e-38 128.2 3.7 1.1e-09 38.7 0.0 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM27923.1 - 5.9e-27 93.4 3.8 1.2e-10 41.4 0.0 6.7 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 GAM27923.1 - 3.4e-24 84.2 5.2 9.4e-05 22.7 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 GAM27923.1 - 3.8e-24 82.1 5.6 8.2e-05 22.7 0.0 8.8 8 0 0 8 8 8 5 Ankyrin repeat CBM_20 PF00686.19 GAM27923.1 - 7.2e-16 57.9 0.0 2.2e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Starch binding domain SPX PF03105.19 GAM27923.1 - 0.00026 21.1 1.1 0.00026 21.1 1.1 4.3 4 1 1 5 5 5 2 SPX domain HGTP_anticodon PF03129.20 GAM27924.1 - 2.4e-23 82.1 0.2 7.2e-23 80.6 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAM27924.1 - 1.4e-09 38.2 0.0 4.1e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) EF-hand_1 PF00036.32 GAM27925.1 - 2.1e-17 61.3 4.4 1.5e-05 24.2 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 GAM27925.1 - 1.5e-15 55.7 3.5 3.3e-05 23.5 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 GAM27925.1 - 2e-12 47.4 1.9 5.3e-09 36.4 0.2 2.5 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM27925.1 - 1e-09 37.4 1.7 0.00032 20.1 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 GAM27925.1 - 4.8e-09 35.9 6.6 0.019 14.8 0.0 3.6 2 2 2 4 4 4 3 EF-hand domain pair Dockerin_1 PF00404.18 GAM27925.1 - 2.3e-05 24.5 1.8 0.014 15.6 0.4 2.6 2 1 0 2 2 2 2 Dockerin type I domain EF-hand_10 PF14788.6 GAM27925.1 - 0.0044 16.9 0.4 0.71 9.8 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 GAM27925.1 - 0.0058 16.9 0.0 4.9 7.5 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain Toprim_2 PF13155.6 GAM27925.1 - 0.047 14.1 0.7 0.65 10.5 0.1 2.3 2 1 1 3 3 3 0 Toprim-like Caleosin PF05042.13 GAM27925.1 - 0.073 13.0 0.2 0.5 10.3 0.0 2.2 2 1 1 3 3 3 0 Caleosin related protein TSP_3 PF02412.18 GAM27925.1 - 0.28 10.9 5.6 2.1 8.1 2.3 2.4 2 0 0 2 2 2 0 Thrombospondin type 3 repeat Fucokinase PF07959.12 GAM27927.1 - 1.7e-116 389.6 0.1 2.1e-116 389.2 0.1 1.1 1 0 0 1 1 1 1 L-fucokinase AATase PF07247.12 GAM27929.1 - 9.6e-08 31.0 1.2 0.00026 19.7 0.3 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 GAM27929.1 - 2.4e-05 23.2 1.1 9.4e-05 21.3 0.4 1.9 2 0 0 2 2 2 1 Condensation domain DUF5450 PF17529.2 GAM27929.1 - 0.031 14.4 0.6 21 5.2 0.0 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5450) AATase PF07247.12 GAM27930.1 - 1.8e-12 46.6 1.2 1.7e-05 23.6 0.3 3.1 2 1 0 2 2 2 2 Alcohol acetyltransferase DUF1184 PF06683.11 GAM27930.1 - 2.1e-05 24.1 0.1 0.091 12.2 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1184) Condensation PF00668.20 GAM27930.1 - 0.0024 16.6 0.2 0.024 13.3 0.2 2.5 3 0 0 3 3 3 1 Condensation domain TniB PF05621.11 GAM27930.1 - 0.067 12.6 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein Apolipoprotein PF01442.18 GAM27931.1 - 1.4e-12 47.9 32.9 6.1e-09 36.0 15.9 2.7 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 GAM27931.1 - 1.7e-07 31.5 22.9 5.4e-07 29.8 17.0 2.1 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 GAM27931.1 - 3.8e-06 27.3 39.2 0.024 15.2 6.2 4.2 1 1 3 4 4 4 3 YtxH-like protein DUF883 PF05957.13 GAM27931.1 - 0.00016 22.2 23.7 0.38 11.4 4.8 4.0 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) Peptidase_M24_C PF16188.5 GAM27931.1 - 0.028 14.5 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 Baculo_PEP_C PF04513.12 GAM27931.1 - 0.073 13.1 0.2 14 5.7 0.0 2.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AT_hook PF02178.19 GAM27931.1 - 0.17 11.8 5.8 0.55 10.3 5.8 1.9 1 0 0 1 1 1 0 AT hook motif ApoO PF09769.9 GAM27931.1 - 0.83 9.6 2.1 11 6.0 0.2 2.8 1 1 2 3 3 3 0 Apolipoprotein O DUF5403 PF17395.2 GAM27931.1 - 1 9.7 5.8 0.63 10.4 0.4 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5403) Muted PF14942.6 GAM27931.1 - 1.6 9.0 29.6 0.42 11.0 13.7 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein OmpH PF03938.14 GAM27931.1 - 3.2 8.1 44.3 4.8 7.5 27.7 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 GAM27931.1 - 4.4 6.8 14.6 24 4.4 14.6 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fzo_mitofusin PF04799.13 GAM27931.1 - 5.8 6.4 15.7 0.64 9.5 4.4 2.8 1 1 2 3 3 3 0 fzo-like conserved region Remorin_C PF03763.13 GAM27931.1 - 7.3 6.5 42.6 14 5.6 15.5 3.1 1 1 2 3 3 3 0 Remorin, C-terminal region Ribosomal_L27A PF00828.19 GAM27933.1 - 7.6e-33 113.9 0.2 1.2e-32 113.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Hexapep PF00132.24 GAM27934.1 - 7.1e-10 38.2 21.0 6.2e-05 22.6 0.6 3.9 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAM27934.1 - 0.00082 19.1 1.6 0.00082 19.1 1.6 4.0 2 2 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 GAM27934.1 - 0.15 11.0 4.3 1.5 7.7 0.3 2.1 1 1 1 2 2 2 0 L-fucokinase DUF4954 PF16314.5 GAM27934.1 - 3.9 5.5 9.3 0.61 8.2 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) UPF0047 PF01894.17 GAM27936.1 - 2.4e-21 76.1 0.0 2.6e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 E3_UbLigase_R4 PF13764.6 GAM27937.1 - 7.7e-190 633.0 19.4 4.2e-189 630.5 8.8 3.5 3 0 0 3 3 3 2 E3 ubiquitin-protein ligase UBR4 ZZ PF00569.17 GAM27937.1 - 3.6e-12 45.9 7.3 3.6e-12 45.9 7.3 3.3 3 0 0 3 3 3 1 Zinc finger, ZZ type UIM PF02809.20 GAM27937.1 - 0.069 13.1 9.5 0.025 14.5 4.4 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif Suv3_N PF18114.1 GAM27937.1 - 0.11 12.6 4.6 0.14 12.3 1.1 3.1 3 0 0 3 3 3 0 Suv3 helical N-terminal domain Mog1 PF04603.12 GAM27938.1 - 4.9e-39 133.9 0.6 6.2e-39 133.5 0.6 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Rap_GAP PF02145.15 GAM27940.1 - 7.5e-58 195.1 2.0 8.3e-58 195.0 0.8 1.6 2 0 0 2 2 2 1 Rap/ran-GAP NAGLU PF05089.12 GAM27941.1 - 6.3e-140 465.9 9.6 8.6e-140 465.4 9.6 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 GAM27941.1 - 2.3e-69 233.9 4.1 3.1e-69 233.5 4.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 GAM27941.1 - 1.4e-18 66.4 0.0 2.9e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain GST_C_3 PF14497.6 GAM27942.1 - 7.9e-22 77.3 0.2 1.5e-21 76.4 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM27942.1 - 6e-11 42.5 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM27942.1 - 1.3e-08 34.9 0.1 2.5e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM27942.1 - 0.0032 17.4 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3872 PF12988.7 GAM27942.1 - 0.18 11.6 1.1 1.5 8.7 1.1 2.1 1 1 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) LRR_4 PF12799.7 GAM27944.1 - 8.3e-05 22.9 48.3 0.13 12.7 0.3 8.4 4 2 4 8 8 8 7 Leucine Rich repeats (2 copies) Carm_PH PF17888.1 GAM27944.1 - 0.007 16.7 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_6 PF13516.6 GAM27944.1 - 0.079 13.0 61.4 0.4 10.8 0.0 13.1 15 0 0 15 15 15 0 Leucine Rich repeat LRR_1 PF00560.33 GAM27944.1 - 0.22 12.2 39.3 55 4.9 0.3 11.3 9 2 0 9 9 9 0 Leucine Rich Repeat PDEase_II PF02112.15 GAM27945.1 - 6.9e-82 275.3 0.1 8.6e-82 275.0 0.1 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II UCH PF00443.29 GAM27946.1 - 1.2e-16 61.0 0.0 9.4e-16 58.1 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM27946.1 - 0.018 14.7 0.1 0.039 13.6 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase CBM_20 PF00686.19 GAM27946.1 - 0.034 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Starch binding domain RRF PF01765.19 GAM27947.1 - 1.1e-44 152.3 0.6 1.3e-44 152.0 0.6 1.1 1 0 0 1 1 1 1 Ribosome recycling factor TFIIF_alpha PF05793.12 GAM27948.1 - 0.51 8.9 40.4 0.91 8.0 40.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 GAM27948.1 - 9.7 5.4 36.1 0.022 14.2 25.5 1.8 2 0 0 2 2 2 0 BUD22 Methyltransf_18 PF12847.7 GAM27949.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ELFV_dehydrog PF00208.21 GAM27950.1 - 7.5e-54 183.0 0.0 1.1e-53 182.5 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 GAM27950.1 - 6.2e-24 83.7 0.1 4.9e-16 57.5 0.1 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 GAM27950.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Endotoxin_N PF03945.14 GAM27951.1 - 2.1e-37 129.0 2.4 3.8e-37 128.2 2.4 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Epimerase PF01370.21 GAM27952.1 - 3e-14 53.1 0.0 7.5e-14 51.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAM27952.1 - 3.5e-07 30.3 0.0 6.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAM27952.1 - 9.2e-06 25.3 0.3 0.079 12.3 0.1 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAM27952.1 - 2.9e-05 23.7 2.2 4.8e-05 23.0 2.2 1.3 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 GAM27952.1 - 5e-05 22.8 0.4 0.0001 21.8 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_2 PF03446.15 GAM27952.1 - 0.001 19.2 0.2 0.0023 18.1 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 GAM27952.1 - 0.027 13.6 0.3 0.052 12.7 0.3 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.26 GAM27952.1 - 0.11 12.4 0.2 0.27 11.2 0.1 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 GAM27952.1 - 0.12 12.2 3.8 1 9.2 1.8 2.5 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4431 PF14485.6 GAM27952.1 - 0.17 11.7 0.2 0.35 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) zf-A20 PF01754.16 GAM27953.1 - 1.5e-09 37.6 9.2 4.2e-09 36.2 9.2 1.8 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 GAM27953.1 - 9e-06 25.8 6.1 9e-06 25.8 6.1 1.7 2 0 0 2 2 2 1 AN1-like Zinc finger DUF5556 PF17711.1 GAM27953.1 - 3.2 7.7 10.6 2 8.3 0.9 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5556) Eno-Rase_NADH_b PF12242.8 GAM27955.1 - 0.12 12.1 0.5 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase BAR PF03114.18 GAM27956.1 - 7.3e-20 71.6 14.6 8.2e-20 71.5 14.6 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 GAM27956.1 - 1.5e-13 51.0 9.5 1.5e-13 51.0 9.5 1.4 1 1 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 GAM27956.1 - 8.1e-08 32.1 14.7 1.1e-07 31.7 14.7 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR_2 PF10455.9 GAM27956.1 - 1.2e-07 31.2 12.9 1.5e-07 30.8 12.9 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking V-ATPase_H_C PF11698.8 GAM27956.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.4 2 1 1 3 3 3 0 V-ATPase subunit H TSNAXIP1_N PF15739.5 GAM27956.1 - 0.61 10.5 11.5 0.19 12.1 5.2 3.0 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus DUF4446 PF14584.6 GAM27956.1 - 5.3 7.0 10.6 9.3 6.2 0.2 3.7 2 1 3 5 5 5 0 Protein of unknown function (DUF4446) DUF1664 PF07889.12 GAM27957.1 - 0.0071 16.4 6.6 0.015 15.4 6.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Spc29 PF17082.5 GAM27957.1 - 0.0073 16.2 6.3 0.0073 16.2 6.3 2.1 1 1 0 2 2 2 1 Spindle Pole Component 29 KASH_CCD PF14662.6 GAM27957.1 - 0.012 15.5 11.2 0.02 14.7 11.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF812 PF05667.11 GAM27957.1 - 0.02 13.8 11.0 0.025 13.5 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3450 PF11932.8 GAM27957.1 - 0.09 12.1 9.5 0.16 11.2 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ly49 PF08391.10 GAM27957.1 - 0.21 12.0 6.8 0.44 10.9 6.8 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2514 PF10721.9 GAM27957.1 - 0.36 10.9 2.0 0.57 10.2 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) FapA PF03961.13 GAM27957.1 - 0.51 8.9 5.7 0.83 8.2 5.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A bZIP_2 PF07716.15 GAM27957.1 - 4.4 7.5 10.6 3.2 7.9 0.3 2.4 2 0 0 2 2 2 0 Basic region leucine zipper O-antigen_lig PF13425.6 GAM27957.1 - 4.8 5.8 4.3 6.9 5.3 4.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DivIC PF04977.15 GAM27957.1 - 8.5 6.2 11.3 3.2 7.6 0.3 2.3 1 1 1 2 2 2 0 Septum formation initiator Arf PF00025.21 GAM27958.1 - 1.4e-74 249.3 0.0 1.6e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM27958.1 - 3.1e-13 50.0 0.0 4.2e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAM27958.1 - 1.4e-12 47.5 0.2 1.3e-07 31.1 0.0 2.8 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GAM27958.1 - 3.9e-11 42.8 0.0 4.5e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAM27958.1 - 9e-11 41.5 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAM27958.1 - 1.1e-07 31.4 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM27958.1 - 0.00014 21.9 0.0 0.00086 19.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM27958.1 - 0.016 14.7 0.1 0.091 12.3 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAM27958.1 - 0.044 12.7 0.0 0.22 10.4 0.0 2.1 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DLIC PF05783.11 GAM27958.1 - 0.17 10.7 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) WH2 PF02205.20 GAM27959.1 - 0.00019 21.2 0.1 0.057 13.3 0.0 2.5 1 1 1 2 2 2 2 WH2 motif Drf_FH1 PF06346.12 GAM27959.1 - 0.13 12.0 56.0 0.036 13.8 53.2 1.4 2 0 0 2 2 2 0 Formin Homology Region 1 YihI PF04220.12 GAM27959.1 - 0.63 9.7 9.7 1.3 8.7 9.7 1.4 1 0 0 1 1 1 0 Der GTPase activator (YihI) SUIM_assoc PF16619.5 GAM27959.1 - 2.2 8.4 15.0 0.26 11.4 8.6 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ANAPC4 PF12896.7 GAM27960.1 - 4.5e-22 78.5 1.3 6.7e-22 78.0 1.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 GAM27960.1 - 4.7e-21 74.9 0.0 9.7e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain LRR_6 PF13516.6 GAM27961.1 - 8.8e-43 140.7 79.6 0.00039 20.3 0.5 18.0 19 0 0 19 19 19 15 Leucine Rich repeat LRR_4 PF12799.7 GAM27961.1 - 7.2e-19 67.6 50.5 0.00047 20.5 1.5 11.6 8 3 4 12 12 12 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM27961.1 - 1.6e-11 43.1 30.8 5.5 8.0 0.1 15.5 16 2 0 16 16 16 4 Leucine Rich Repeat LRR_8 PF13855.6 GAM27961.1 - 3e-09 36.5 62.7 0.0018 18.0 5.2 12.5 4 4 6 10 10 10 6 Leucine rich repeat RabGAP-TBC PF00566.18 GAM27962.1 - 2.6e-31 108.9 0.8 7e-31 107.6 0.8 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TLD PF07534.16 GAM27962.1 - 5e-23 81.9 0.0 9.3e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 TLD RWP-RK PF02042.15 GAM27964.1 - 0.16 12.0 0.4 0.55 10.2 0.4 1.9 1 1 0 1 1 1 0 RWP-RK domain RhoGAP PF00620.27 GAM27966.1 - 2.2e-27 95.7 0.1 1.9e-26 92.7 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 GAM27966.1 - 1.2e-12 48.0 0.4 1.2e-12 48.0 0.4 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Vps5 PF09325.10 GAM27966.1 - 0.015 14.9 2.1 0.03 13.9 2.1 1.5 1 0 0 1 1 1 0 Vps5 C terminal like ZapB PF06005.12 GAM27967.1 - 0.0049 17.3 1.9 0.0049 17.3 1.9 2.1 2 0 0 2 2 2 1 Cell division protein ZapB SLATT_6 PF18169.1 GAM27967.1 - 0.02 14.5 0.3 0.035 13.7 0.3 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 DUF4618 PF15397.6 GAM27967.1 - 0.03 13.7 6.5 0.039 13.4 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DivIC PF04977.15 GAM27967.1 - 0.038 13.8 1.6 0.11 12.2 1.1 2.1 2 0 0 2 2 2 0 Septum formation initiator JAKMIP_CC3 PF16034.5 GAM27967.1 - 0.044 13.7 5.6 0.44 10.5 2.2 2.4 2 0 0 2 2 2 0 JAKMIP CC3 domain CEP63 PF17045.5 GAM27967.1 - 0.045 13.6 4.4 0.096 12.6 4.4 1.5 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa GSHPx PF00255.19 GAM27967.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase YabA PF06156.13 GAM27967.1 - 0.11 13.1 1.7 0.72 10.5 0.4 2.4 2 0 0 2 2 2 0 Initiation control protein YabA NPV_P10 PF05531.12 GAM27967.1 - 0.27 11.7 3.3 0.71 10.4 2.9 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TolA_bind_tri PF16331.5 GAM27967.1 - 1.6 8.8 13.7 13 5.9 0.3 3.6 2 2 1 3 3 3 0 TolA binding protein trimerisation SlyX PF04102.12 GAM27967.1 - 5.5 7.7 7.4 2.9 8.6 3.5 2.6 2 1 1 3 3 3 0 SlyX DUF572 PF04502.13 GAM27968.1 - 0.11 12.2 18.8 0.17 11.4 18.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DEC-1_N PF04625.13 GAM27970.1 - 1.1 8.2 6.3 1.4 7.9 6.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ribophorin_I PF04597.14 GAM27971.1 - 2e-125 419.5 3.4 2e-125 419.5 3.4 1.5 2 0 0 2 2 2 1 Ribophorin I TIP49 PF06068.13 GAM27972.1 - 7.1e-169 561.6 0.4 9.2e-169 561.2 0.4 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GAM27972.1 - 3.4e-22 78.3 0.0 2.8e-21 75.4 0.1 2.3 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 GAM27972.1 - 2.9e-11 43.9 1.2 2.2e-07 31.4 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAM27972.1 - 8.7e-10 38.6 0.2 4e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAM27972.1 - 7.2e-07 29.6 0.1 0.036 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 GAM27972.1 - 2.3e-05 24.4 0.1 0.0039 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM27972.1 - 8.1e-05 23.1 0.0 0.0015 19.0 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 GAM27972.1 - 0.00019 21.1 0.4 0.0004 20.0 0.2 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAM27972.1 - 0.0035 17.1 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 GAM27972.1 - 0.0041 17.1 0.0 1.7 8.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 GAM27972.1 - 0.0054 16.1 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 GAM27972.1 - 0.0055 16.1 3.9 0.049 13.0 0.1 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 GAM27972.1 - 0.0089 15.7 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 GAM27972.1 - 0.021 15.1 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GAM27972.1 - 0.023 14.5 0.7 0.059 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAM27972.1 - 0.023 15.2 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mucin PF01456.17 GAM27972.1 - 0.03 14.3 23.7 0.056 13.4 23.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein ResIII PF04851.15 GAM27972.1 - 0.04 13.9 0.3 1.6 8.7 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAM27972.1 - 0.044 14.1 7.1 0.56 10.5 0.1 3.0 3 1 0 3 3 3 0 AAA domain NACHT PF05729.12 GAM27972.1 - 0.062 13.2 0.1 0.17 11.8 0.0 1.7 2 0 0 2 2 1 0 NACHT domain TsaE PF02367.17 GAM27972.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 GAM27972.1 - 0.086 12.3 0.1 0.086 12.3 0.1 2.0 2 0 0 2 2 1 0 PhoH-like protein Zeta_toxin PF06414.12 GAM27972.1 - 0.09 12.0 0.2 0.19 11.0 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 GAM27972.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Macoilin PF09726.9 GAM27972.1 - 0.23 10.0 2.7 0.34 9.4 2.7 1.2 1 0 0 1 1 1 0 Macoilin family AAA_7 PF12775.7 GAM27972.1 - 0.27 10.7 0.0 0.27 10.7 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region NUDE_C PF04880.13 GAM27972.1 - 0.55 10.7 6.3 1 9.8 6.3 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region GREB1 PF15782.5 GAM27973.1 - 4.5 4.3 12.8 5.7 3.9 12.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NAP PF00956.18 GAM27974.1 - 4.4e-47 160.5 3.8 7.2e-47 159.8 3.8 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) BUD22 PF09073.10 GAM27974.1 - 0.029 13.7 10.7 0.042 13.2 10.7 1.2 1 0 0 1 1 1 0 BUD22 DUF1439 PF07273.12 GAM27974.1 - 0.033 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1439) Tub_N PF16322.5 GAM27974.1 - 0.49 10.8 5.9 1.3 9.4 6.0 1.6 1 1 0 1 1 1 0 Tubby N-terminal CENP-B_dimeris PF09026.10 GAM27974.1 - 7.5 7.0 24.9 3.3 8.2 15.2 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pkinase PF00069.25 GAM27975.1 - 4e-65 219.8 0.0 3.8e-41 141.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27975.1 - 2.5e-30 105.6 0.0 4.5e-23 81.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase PX PF00787.24 GAM27975.1 - 9.1e-18 64.3 0.1 1.9e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 PX domain PH PF00169.29 GAM27975.1 - 4.4e-17 62.5 0.0 1e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 GAM27975.1 - 4.7e-06 26.1 0.0 0.0017 17.7 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 GAM27975.1 - 0.00029 19.9 1.4 0.00071 18.6 0.1 2.2 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 GAM27975.1 - 0.0027 17.7 0.0 0.0027 17.7 0.0 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family PH_8 PF15409.6 GAM27975.1 - 0.033 14.5 0.0 0.092 13.0 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 GAM27975.1 - 0.092 13.1 0.1 5.7 7.3 0.1 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 GAM27975.1 - 0.39 11.2 3.1 0.52 10.8 0.5 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain Vel1p PF10339.9 GAM27976.1 - 0.026 13.9 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 Yeast-specific zinc responsive Vps35 PF03635.17 GAM27977.1 - 8.6e-255 847.7 26.5 9.9e-255 847.5 26.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Cyclin_C_2 PF16899.5 GAM27978.1 - 5.8e-16 58.8 0.8 4.6e-15 55.9 0.1 2.4 2 1 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 GAM27978.1 - 1.1e-12 47.9 1.3 1.6e-12 47.3 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 GAM27978.1 - 0.00022 21.2 0.0 0.00057 19.9 0.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin PF08613.11 GAM27978.1 - 0.25 11.7 0.1 0.25 11.7 0.1 2.1 2 0 0 2 2 2 0 Cyclin Tmemb_170 PF10190.9 GAM27979.1 - 1.7e-26 92.7 12.2 2.2e-26 92.3 12.2 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Alpha-amylase PF00128.24 GAM27980.1 - 1.4e-16 61.0 2.1 1.9e-15 57.3 2.1 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 GAM27980.1 - 0.00033 19.9 0.2 0.00051 19.2 0.2 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Prokineticin PF06607.11 GAM27981.1 - 0.00069 19.9 2.9 0.00069 19.9 2.9 3.1 2 2 1 3 3 3 1 Prokineticin Dopey_N PF04118.14 GAM27983.1 - 1.1e-87 294.0 4.4 2e-87 293.2 0.4 3.1 2 0 0 2 2 2 1 Dopey, N-terminal Spt20 PF12090.8 GAM27983.1 - 0.37 10.4 10.5 1.1 8.9 10.5 1.8 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 GAM27983.1 - 0.45 10.6 11.5 1.4 9.1 11.5 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ATP-synt_ab PF00006.25 GAM27984.1 - 2e-61 207.4 0.0 3e-61 206.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAM27984.1 - 8.4e-18 64.7 1.4 2.1e-16 60.2 1.4 2.5 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 GAM27984.1 - 0.0095 15.2 1.1 0.019 14.2 0.2 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 GAM27984.1 - 0.024 15.1 0.2 0.31 11.5 0.0 2.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 GAM27984.1 - 0.033 14.1 0.4 0.083 12.8 0.2 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 GAM27984.1 - 0.037 14.4 0.1 0.11 12.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 GAM27984.1 - 0.039 14.4 0.3 0.45 10.9 0.0 2.9 4 0 0 4 4 3 0 RNA helicase NACHT PF05729.12 GAM27984.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain VitK2_biosynth PF02621.14 GAM27984.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Menaquinone biosynthesis ATPase PF06745.13 GAM27984.1 - 0.065 12.6 2.0 0.086 12.2 0.4 2.1 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 GAM27984.1 - 0.12 12.9 2.9 0.83 10.2 0.3 2.9 3 0 0 3 3 3 0 ABC transporter AAA_22 PF13401.6 GAM27984.1 - 0.19 12.0 0.6 0.87 9.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 GAM27984.1 - 0.21 11.9 0.7 0.55 10.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain Arfaptin PF06456.13 GAM27984.1 - 0.76 9.3 3.7 3.1 7.3 1.2 2.4 2 0 0 2 2 2 0 Arfaptin-like domain KRE1 PF17056.5 GAM27984.1 - 2.3 8.0 4.5 18 5.2 0.1 2.8 3 0 0 3 3 3 0 Killer toxin-resistance protein 1 3-HAO PF06052.12 GAM27985.1 - 3.3e-59 198.9 0.1 3.8e-59 198.6 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 GAM27985.1 - 8e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain zf-RRN7 PF11781.8 GAM27985.1 - 0.0053 16.4 5.0 0.48 10.2 0.4 2.3 2 0 0 2 2 2 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Cytochrome_C7 PF14522.6 GAM27985.1 - 0.018 15.0 0.9 0.046 13.7 0.9 1.6 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-BED PF02892.15 GAM27985.1 - 0.024 14.6 0.3 7.7 6.6 0.0 2.3 2 0 0 2 2 2 0 BED zinc finger zf-CHY PF05495.12 GAM27985.1 - 0.025 15.0 0.5 3.7 8.1 0.0 2.2 2 0 0 2 2 2 0 CHY zinc finger AraC_binding PF02311.19 GAM27985.1 - 0.079 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_6 PF12852.7 GAM27985.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cupin MCR PF18509.1 GAM27985.1 - 0.58 9.8 4.2 4.7 6.9 0.8 2.8 2 0 0 2 2 2 0 Magnetochrome domain FNIP PF05725.12 GAM27987.1 - 1.3e-54 182.1 23.2 4.9e-10 39.4 2.5 8.5 6 1 4 10 10 10 9 FNIP Repeat Glyco_hydro_35 PF01301.19 GAM27988.1 - 9.8e-107 357.2 8.4 1.5e-106 356.6 8.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 GHD PF17834.1 GAM27988.1 - 3.1e-05 23.9 0.2 7.2e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Beta-sandwich domain in beta galactosidase Palm_thioest PF02089.15 GAM27989.1 - 4.2e-88 295.3 0.0 4.9e-88 295.1 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 GAM27989.1 - 0.00071 19.2 0.0 0.002 17.7 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 GAM27989.1 - 0.0054 16.4 0.0 0.0098 15.6 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold SF3A3 PF16837.5 GAM27989.1 - 0.016 15.7 1.0 0.033 14.7 0.5 1.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF915 PF06028.11 GAM27989.1 - 0.066 12.5 0.2 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) FNIP PF05725.12 GAM27990.1 - 1.1e-57 191.9 10.1 2.2e-10 40.5 0.1 7.8 5 1 3 8 8 8 8 FNIP Repeat Glyco_hydro_35 PF01301.19 GAM27991.1 - 1.6e-92 310.6 12.4 2.2e-92 310.1 12.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 GHD PF17834.1 GAM27991.1 - 7.9e-08 32.2 0.1 1.9e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Beta-sandwich domain in beta galactosidase Pkinase PF00069.25 GAM27992.1 - 3.8e-63 213.3 0.1 7.9e-63 212.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM27992.1 - 1.1e-48 165.8 0.0 1.9e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM27992.1 - 2.4e-06 27.1 0.7 0.00012 21.5 0.0 2.9 3 1 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 GAM27992.1 - 0.00016 20.6 0.0 0.00016 20.6 0.0 2.6 3 1 0 3 3 3 1 Fungal protein kinase RIO1 PF01163.22 GAM27992.1 - 0.0062 16.2 0.2 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 GAM27992.1 - 0.08 12.5 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL ECSCR PF15820.5 GAM27992.1 - 0.091 12.6 0.6 3.6 7.5 0.1 2.7 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator US30 PF17624.2 GAM27993.1 - 0.051 12.6 0.1 0.057 12.5 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function EF-hand_1 PF00036.32 GAM27995.1 - 1.3e-23 80.7 13.1 6.4e-05 22.2 1.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 GAM27995.1 - 1.1e-20 73.8 14.7 4.7e-10 39.8 1.8 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GAM27995.1 - 1.7e-19 68.0 11.4 5.8e-05 22.7 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAM27995.1 - 3.9e-16 57.7 17.1 0.00047 19.5 1.2 5.0 5 1 1 6 6 6 4 EF hand EF-hand_8 PF13833.6 GAM27995.1 - 2.6e-09 36.8 15.8 0.0034 17.2 1.0 4.4 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM27995.1 - 1.3e-07 31.9 0.6 0.021 15.1 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAM27995.1 - 2.2e-06 27.6 8.0 0.051 13.5 0.5 3.6 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 GAM27995.1 - 0.0031 16.1 0.1 0.0036 15.9 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5580) RE_LlaJI PF09563.10 GAM27995.1 - 0.0082 15.4 0.5 0.68 9.1 0.0 2.0 1 1 1 2 2 2 2 LlaJI restriction endonuclease SPG4 PF17325.2 GAM27995.1 - 0.013 16.6 0.1 0.028 15.5 0.1 1.6 1 0 0 1 1 1 0 Stationary phase protein 4 EF-hand_9 PF14658.6 GAM27995.1 - 0.1 12.9 0.5 3.1 8.2 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain Homeodomain PF00046.29 GAM27996.1 - 2.2e-15 56.2 7.6 3.7e-15 55.5 7.6 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAM27996.1 - 2.1e-06 27.5 0.3 5.3e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain AC_N PF16214.5 GAM27996.1 - 0.27 10.3 2.5 0.39 9.8 2.5 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Beta-lactamase PF00144.24 GAM27997.1 - 1.2e-34 120.0 0.0 2.2e-34 119.2 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase DHR-2 PF06920.13 GAM27998.1 - 8.6e-67 226.0 9.5 2.5e-66 224.4 9.5 1.7 1 0 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 GAM27998.1 - 3.8e-46 157.7 0.7 3.7e-33 115.0 0.0 2.9 3 0 0 3 3 3 2 DOCK N-terminus DOCK-C2 PF14429.6 GAM27998.1 - 1e-29 103.8 0.7 3.3e-29 102.1 0.0 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 GAM27998.1 - 1.5e-06 28.0 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM27998.1 - 0.00012 21.6 0.0 0.00027 20.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain FNIP PF05725.12 GAM27999.1 - 4.9e-59 196.2 11.9 1.3e-12 47.6 0.1 7.0 3 1 6 9 9 9 8 FNIP Repeat LRR_1 PF00560.33 GAM27999.1 - 1.6 9.6 6.4 18 6.3 0.1 5.1 4 2 0 4 4 4 0 Leucine Rich Repeat FNIP PF05725.12 GAM28000.1 - 4.3e-61 202.8 33.1 1.1e-14 54.3 1.1 7.2 3 2 4 7 7 7 7 FNIP Repeat FNIP PF05725.12 GAM28001.1 - 9.4e-62 204.9 42.2 6.8e-16 58.2 0.3 7.2 4 1 3 8 8 8 8 FNIP Repeat LRR_5 PF13306.6 GAM28001.1 - 0.15 12.0 2.1 10 6.1 0.0 3.4 4 1 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 GAM28002.1 - 9.2e-65 214.6 14.6 1.3e-13 50.9 0.2 8.2 5 1 3 9 9 9 8 FNIP Repeat LapA_dom PF06305.11 GAM28003.1 - 0.03 14.1 0.4 0.061 13.1 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SieB PF14163.6 GAM28003.1 - 0.04 13.4 0.1 0.12 11.8 0.1 1.8 1 0 0 1 1 1 0 Super-infection exclusion protein B Ras PF00071.22 GAM28004.1 - 1.6e-47 161.1 0.0 2e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM28004.1 - 5e-28 97.7 0.0 7.4e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM28004.1 - 2.2e-11 43.5 0.0 2.7e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM28004.1 - 8e-06 25.4 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM28004.1 - 9.9e-06 25.2 0.1 0.0027 17.3 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAM28004.1 - 5e-05 23.4 0.0 8.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM28004.1 - 0.0029 17.5 0.1 0.087 12.7 0.1 2.3 2 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 GAM28004.1 - 0.0082 15.7 0.3 0.17 11.5 0.1 2.2 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 GAM28004.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 GAM28004.1 - 0.021 14.7 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Septin PF00735.18 GAM28004.1 - 0.031 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 GAM28004.1 - 0.038 13.5 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 GAM28004.1 - 0.048 13.9 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 GAM28004.1 - 0.073 12.5 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 GAM28004.1 - 0.083 12.9 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Dynamin family DUF5471 PF17565.2 GAM28005.1 - 0.03 14.6 1.6 0.048 13.9 1.4 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5471) FNIP PF05725.12 GAM28006.1 - 4.6e-69 228.3 24.8 1.8e-12 47.2 0.9 8.0 4 1 4 9 9 9 8 FNIP Repeat Coiled PF05710.12 GAM28007.1 - 6.6e-18 65.3 7.6 8e-18 65.1 7.6 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 GAM28008.1 - 1.3e-17 64.4 12.6 1.5e-17 64.2 12.6 1.1 1 0 0 1 1 1 1 Coiled coil Tetraspanin PF00335.20 GAM28010.1 - 0.04 13.6 0.5 0.058 13.1 0.5 1.2 1 0 0 1 1 1 0 Tetraspanin family PRIMA1 PF16101.5 GAM28010.1 - 3.6 7.6 8.0 8.1 6.5 4.3 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 UCH PF00443.29 GAM28012.1 - 1e-55 189.0 10.0 6e-55 186.5 10.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM28012.1 - 4.9e-24 85.5 25.3 3.6e-23 82.7 25.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Miga PF10265.9 GAM28012.1 - 0.0058 15.7 11.2 0.0078 15.2 11.2 1.1 1 0 0 1 1 1 1 Mitoguardin Atrophin-1 PF03154.15 GAM28012.1 - 0.38 9.0 10.5 0.57 8.4 10.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family SPX PF03105.19 GAM28012.1 - 0.75 9.6 12.6 1.1 9.1 12.6 1.2 1 0 0 1 1 1 0 SPX domain NST1 PF13945.6 GAM28012.1 - 9 6.4 13.9 17 5.4 13.9 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Sod_Cu PF00080.20 GAM28013.1 - 2.3e-31 108.9 0.6 3.6e-29 101.7 0.1 2.2 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 GAM28013.1 - 0.1 13.6 0.1 0.26 12.2 0.1 1.8 1 1 0 1 1 1 0 CHRD domain SdrD_B PF17210.3 GAM28014.1 - 2.5e-62 208.0 80.1 1.4e-08 35.0 1.2 13.6 12 3 0 12 12 12 11 SdrD B-like domain DUF2012 PF09430.10 GAM28014.1 - 4.8e-19 68.7 0.0 0.06 13.5 0.0 9.5 11 0 0 11 11 11 5 Protein of unknown function (DUF2012) Y_Y_Y PF07495.13 GAM28014.1 - 4.3e-05 23.4 25.3 3.6 7.6 0.0 9.6 11 0 0 11 11 11 4 Y_Y_Y domain PS-DH PF14765.6 GAM28014.1 - 0.0052 16.0 0.0 29 3.8 0.0 5.6 7 0 0 7 7 7 0 Polyketide synthase dehydratase DUF4365 PF14280.6 GAM28014.1 - 0.017 15.1 0.0 45 4.0 0.0 5.0 7 0 0 7 7 7 0 Domain of unknown function (DUF4365) SpaA PF17802.1 GAM28014.1 - 0.018 15.4 0.8 0.018 15.4 0.8 12.7 8 2 0 8 8 8 0 Prealbumin-like fold domain DUF1093 PF06486.11 GAM28014.1 - 0.047 14.4 5.6 1.3e+02 3.3 0.1 6.5 7 0 0 7 7 7 0 Protein of unknown function (DUF1093) Lustrin_cystein PF14625.6 GAM28014.1 - 0.8 10.1 2.9 4.4 7.8 2.9 2.4 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Endotoxin_N PF03945.14 GAM28016.1 - 5e-05 23.1 0.0 6.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain eIF_4EBP PF05456.11 GAM28018.1 - 1.9e-22 79.3 14.4 1.9e-21 76.2 14.4 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) GH3 PF03321.13 GAM28018.1 - 0.12 11.2 3.3 0.13 11.0 3.0 1.2 1 1 0 1 1 1 0 GH3 auxin-responsive promoter DnaJ PF00226.31 GAM28019.1 - 6.8e-21 74.2 0.7 6.8e-21 74.2 0.7 2.0 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.22 GAM28019.1 - 1.1e-05 25.1 0.6 0.0026 17.5 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mit_KHE1 PF10173.9 GAM28019.1 - 6.7 6.8 11.8 16 5.5 11.8 1.9 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DAGK_cat PF00781.24 GAM28020.1 - 6.1e-30 103.4 0.0 1.8e-29 101.9 0.0 1.9 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3456 PF11938.8 GAM28020.1 - 0.043 14.3 0.1 0.043 14.3 0.1 2.8 3 1 0 3 3 3 0 TLR4 regulator and MIR-interacting MSAP NAD_kinase PF01513.21 GAM28020.1 - 0.077 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP-NAD kinase MAS20 PF02064.15 GAM28020.1 - 1.5 8.9 6.6 3.1 7.9 0.3 3.0 3 0 0 3 3 3 0 MAS20 protein import receptor XPG_N PF00752.17 GAM28021.1 - 8.1e-24 84.0 0.0 3e-23 82.2 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 GAM28021.1 - 1.6e-21 76.4 0.0 2e-20 73.0 0.0 3.1 1 0 0 1 1 1 1 XPG I-region UBM PF14377.6 GAM28021.1 - 0.0012 18.2 0.1 0.0041 16.5 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin binding region 5_3_exonuc PF01367.20 GAM28021.1 - 0.074 13.7 1.4 1 10.0 0.0 2.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Mucin PF01456.17 GAM28021.1 - 5.8 6.9 35.1 0.27 11.2 18.3 3.7 3 0 0 3 3 3 0 Mucin-like glycoprotein RUN PF02759.19 GAM28022.1 - 0.0062 16.5 0.2 0.033 14.1 0.0 2.3 2 1 0 2 2 2 1 RUN domain zf-U1 PF06220.12 GAM28023.1 - 1.5e-06 27.9 0.4 3e-06 26.9 0.4 1.6 1 0 0 1 1 1 1 U1 zinc finger UPF0564 PF10595.9 GAM28023.1 - 0.075 12.1 24.8 0.54 9.3 9.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 DUF4606 PF15379.6 GAM28023.1 - 2.9 8.2 11.9 0.2 11.9 1.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4606) TFIIA PF03153.13 GAM28024.1 - 0.0019 18.3 16.6 0.0022 18.1 16.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 GAM28024.1 - 1.8 7.2 7.3 2.2 6.9 7.3 1.1 1 0 0 1 1 1 0 Presenilin Spc7_N PF15402.6 GAM28024.1 - 9.8 4.3 13.6 12 4.0 13.6 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Coiled PF05710.12 GAM28025.1 - 3.2e-15 56.7 14.6 3.8e-15 56.5 14.6 1.0 1 0 0 1 1 1 1 Coiled coil Amidase PF01425.21 GAM28026.1 - 2.3e-137 458.6 0.2 2.6e-137 458.5 0.2 1.0 1 0 0 1 1 1 1 Amidase BRCT_2 PF16589.5 GAM28026.1 - 0.054 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain UPF0004 PF00919.20 GAM28027.1 - 5.4e-31 106.5 0.2 1.3e-30 105.3 0.2 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 GAM28027.1 - 6e-31 108.1 0.0 1.2e-30 107.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 GAM28027.1 - 2.1e-06 27.6 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 GAM28027.1 - 0.093 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 TRAM domain SelP_N PF04592.14 GAM28027.1 - 4 6.8 11.9 0.77 9.1 8.0 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Melibiase_2 PF16499.5 GAM28028.1 - 2.8e-75 253.1 4.9 4.5e-75 252.5 4.9 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 GAM28028.1 - 1.6e-19 69.7 0.1 5.3e-19 68.1 0.2 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 GAM28028.1 - 5.3e-05 22.3 0.0 9.5e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 GAM28028.1 - 0.005 17.0 0.0 0.0092 16.2 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Glyco_hydro_97 PF10566.9 GAM28028.1 - 0.0097 15.2 0.2 0.014 14.7 0.2 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 Glycogen_syn PF05693.13 GAM28028.1 - 0.14 10.6 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase TrbC PF04956.13 GAM28028.1 - 0.25 11.6 3.8 0.19 11.9 1.0 2.2 3 0 0 3 3 3 0 TrbC/VIRB2 family AIF_C PF14721.6 GAM28029.1 - 0.42 11.0 4.0 0.88 9.9 4.0 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BNR_3 PF13859.6 GAM28029.1 - 1.1 8.4 5.0 1.5 8.0 4.3 1.5 2 0 0 2 2 2 0 BNR repeat-like domain CBS PF00571.28 GAM28030.1 - 1.9e-20 73.1 7.5 8.6e-07 29.3 0.0 5.0 4 1 0 4 4 4 4 CBS domain ThiF PF00899.21 GAM28031.1 - 2.9e-109 364.1 0.1 1.7e-70 237.1 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GAM28031.1 - 1.2e-92 310.4 3.7 2.1e-92 309.6 3.7 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 GAM28031.1 - 7e-32 110.0 0.8 2.1e-31 108.4 0.8 1.9 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 GAM28031.1 - 3e-28 97.8 1.0 8.8e-28 96.3 0.6 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 GAM28031.1 - 2.9e-18 65.8 1.2 8.6e-18 64.3 0.8 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Dimerisation2 PF16864.5 GAM28031.1 - 0.073 13.1 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain C1-set PF07654.15 GAM28031.1 - 0.15 12.5 0.3 0.47 10.9 0.3 1.8 1 0 0 1 1 1 0 Immunoglobulin C1-set domain CDC50 PF03381.15 GAM28032.1 - 6.9e-90 301.4 0.7 9.6e-90 300.9 0.3 1.5 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Oxysterol_BP PF01237.18 GAM28033.1 - 1.1e-46 159.4 2.6 3.3e-44 151.2 2.6 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF1084 PF06454.11 GAM28034.1 - 2.7e-16 59.7 21.4 3.3e-16 59.5 21.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) FNIP PF05725.12 GAM28037.1 - 2.6e-57 190.7 19.8 1.2e-10 41.4 0.0 8.3 5 3 4 9 9 9 9 FNIP Repeat Methyltransf_5 PF01795.19 GAM28038.1 - 8.7e-82 275.1 0.0 4e-81 272.9 0.0 1.8 1 1 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 GAM28038.1 - 0.012 15.4 0.0 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DUF1084 PF06454.11 GAM28039.1 - 2.5e-14 53.3 16.2 3.5e-14 52.8 16.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Topoisom_bac PF01131.20 GAM28041.1 - 3.3e-107 359.1 0.0 4.1e-107 358.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 GAM28041.1 - 8.1e-17 61.3 0.0 1.8e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zf-CHC2 PF01807.20 GAM28041.1 - 0.051 13.4 2.9 0.14 12.0 2.9 1.7 1 0 0 1 1 1 0 CHC2 zinc finger ATC_hydrolase PF14196.6 GAM28041.1 - 0.056 14.2 0.3 0.15 12.8 0.3 1.8 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF4503 PF14951.6 GAM28041.1 - 0.062 11.8 2.6 0.096 11.1 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Toprim_4 PF13662.6 GAM28041.1 - 0.071 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Toprim domain Toprim_2 PF13155.6 GAM28041.1 - 0.17 12.3 0.0 10 6.6 0.0 2.5 2 0 0 2 2 2 0 Toprim-like EXS PF03124.14 GAM28042.1 - 8.6e-90 301.4 32.2 1.5e-89 300.6 32.2 1.4 1 0 0 1 1 1 1 EXS family SPX PF03105.19 GAM28042.1 - 9.9e-40 137.6 9.1 1.7e-39 136.9 9.1 1.3 1 0 0 1 1 1 1 SPX domain DUF3054 PF11255.8 GAM28042.1 - 2.2 8.8 9.8 0.51 10.9 3.3 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF3054) FNIP PF05725.12 GAM28043.1 - 7.7e-40 134.8 4.2 6.7e-10 39.0 0.0 5.0 3 1 3 6 6 6 5 FNIP Repeat Cyt-b5 PF00173.28 GAM28043.1 - 2.4e-20 72.4 0.2 3.6e-20 71.9 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-PHD-like PF15446.6 GAM28044.1 - 0.0026 17.4 1.3 0.0026 17.4 1.3 2.1 2 1 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Mucin PF01456.17 GAM28044.1 - 0.0044 17.0 27.0 0.0044 17.0 27.0 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein TRAPPC-Trs85 PF12739.7 GAM28044.1 - 0.013 14.5 0.4 0.024 13.6 0.4 1.4 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TetR_C_17 PF17922.1 GAM28044.1 - 0.13 12.3 0.1 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain FSA_C PF10479.9 GAM28044.1 - 7.9 4.5 14.1 16 3.5 14.1 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Beta_helix PF13229.6 GAM28045.1 - 9.3e-08 32.1 51.0 0.0018 18.1 8.2 5.7 3 2 2 5 5 5 5 Right handed beta helix region Coiled PF05710.12 GAM28046.1 - 3.6e-13 50.1 6.3 4e-13 50.0 6.3 1.1 1 0 0 1 1 1 1 Coiled coil Glyco_hydro_31 PF01055.26 GAM28047.1 - 2.8e-146 488.2 7.5 3.6e-146 487.8 7.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAM28047.1 - 2.4e-30 105.1 0.1 5.8e-30 103.9 0.1 1.6 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 GAM28047.1 - 3.5e-11 43.2 0.1 3.5e-11 43.2 0.1 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 GAM28047.1 - 0.00012 22.2 0.0 0.00059 20.1 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Ras PF00071.22 GAM28049.1 - 2e-16 60.0 0.2 4.7e-16 58.8 0.2 1.6 1 0 0 1 1 1 1 Ras family LRR_6 PF13516.6 GAM28049.1 - 5.6e-11 41.6 17.0 0.0072 16.3 0.4 5.8 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 GAM28049.1 - 9.5e-05 22.4 1.3 12 6.9 0.0 5.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 GAM28049.1 - 0.00094 19.5 10.3 0.29 11.6 0.4 4.0 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) Borrelia_P83 PF05262.11 GAM28049.1 - 0.0026 16.3 27.2 0.0036 15.9 27.2 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein TPR_5 PF12688.7 GAM28049.1 - 0.048 13.9 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat LRR_8 PF13855.6 GAM28049.1 - 0.22 11.3 9.6 0.55 10.0 1.3 3.6 2 2 0 2 2 2 0 Leucine rich repeat Atrophin-1 PF03154.15 GAM28049.1 - 0.79 7.9 20.3 1.1 7.4 20.3 1.3 1 0 0 1 1 1 0 Atrophin-1 family XRN_M PF17846.1 GAM28049.1 - 1.9 7.3 19.5 3.3 6.6 19.5 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Exonuc_VII_L PF02601.15 GAM28049.1 - 4.4 6.8 15.7 7.5 6.0 15.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit adh_short PF00106.25 GAM28050.1 - 4.9e-12 45.7 1.3 7.5e-11 41.8 1.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM28050.1 - 4.2e-07 29.8 0.1 6e-07 29.2 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAM28050.1 - 1.6e-05 24.5 0.0 3.4e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM28050.1 - 0.0066 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 GAM28050.1 - 0.013 15.1 0.2 0.019 14.5 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Ribosomal_S17_N PF16205.5 GAM28051.1 - 1.5e-28 98.9 0.6 2.7e-28 98.1 0.6 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 GAM28051.1 - 3.3e-25 88.0 0.6 4.8e-25 87.4 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Occludin_ELL PF07303.13 GAM28052.1 - 2.2 9.0 9.9 4.3 8.1 9.9 1.4 1 0 0 1 1 1 0 Occludin homology domain FNIP PF05725.12 GAM28053.1 - 4.2e-103 337.3 30.1 1e-15 57.6 0.8 12.7 7 2 5 15 15 15 14 FNIP Repeat F-box_5 PF18511.1 GAM28053.1 - 3.9e-06 26.3 0.2 8.6e-06 25.2 0.2 1.5 1 0 0 1 1 1 1 F-box LRR_5 PF13306.6 GAM28053.1 - 0.12 12.4 0.0 1.9 8.5 0.0 3.0 3 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) F-box-like PF12937.7 GAM28053.1 - 0.14 12.1 0.2 0.56 10.2 0.2 2.1 1 0 0 1 1 1 0 F-box-like rRNA_processing PF08524.11 GAM28054.1 - 4.6e-12 46.2 21.1 4.6e-12 46.2 21.1 3.1 2 1 1 3 3 3 1 rRNA processing Mucin PF01456.17 GAM28054.1 - 0.068 13.2 16.4 0.12 12.4 16.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein EB PF01683.18 GAM28055.1 - 1.2e-05 25.5 42.0 6.8e-05 23.1 8.0 4.4 2 2 2 4 4 4 4 EB module Endotoxin_N PF03945.14 GAM28056.1 - 5.9e-45 153.7 5.3 8.9e-45 153.1 5.3 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Flp1_like PF16982.5 GAM28056.1 - 0.0098 15.3 0.1 0.022 14.2 0.1 1.6 1 0 0 1 1 1 1 Putative Flagellin, Flp1-like, domain DUF1831 PF08866.10 GAM28056.1 - 0.081 13.4 0.6 0.92 10.0 0.1 2.8 3 0 0 3 3 3 0 Putative amino acid metabolism Flavi_propep PF01570.17 GAM28056.1 - 0.36 10.8 2.3 0.75 9.8 0.7 2.3 2 0 0 2 2 2 0 Flavivirus polyprotein propeptide Mer2 PF09074.10 GAM28056.1 - 0.52 10.1 5.5 0.43 10.4 0.7 2.2 1 1 1 2 2 2 0 Mer2 Endotoxin_N PF03945.14 GAM28057.1 - 5e-43 147.4 6.3 7.5e-43 146.8 6.3 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Flp1_like PF16982.5 GAM28057.1 - 0.012 15.0 0.1 0.027 13.8 0.1 1.6 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Flavi_propep PF01570.17 GAM28057.1 - 0.54 10.3 4.6 0.75 9.8 0.7 2.9 2 1 0 2 2 2 0 Flavivirus polyprotein propeptide Mer2 PF09074.10 GAM28057.1 - 1.2 8.9 6.7 0.61 9.9 0.8 2.2 1 1 1 2 2 2 0 Mer2 ArfGap PF01412.18 GAM28058.1 - 0.0028 17.7 0.1 0.0028 17.7 0.1 3.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Pes-10 PF07149.11 GAM28058.1 - 1.2 8.1 5.7 2 7.4 5.7 1.3 1 0 0 1 1 1 0 Pes-10 Axin_b-cat_bind PF08833.10 GAM28058.1 - 6.5 6.9 13.6 0.056 13.6 4.6 2.3 2 1 0 2 2 2 0 Axin beta-catenin binding domain SMC_N PF02463.19 GAM28059.1 - 1.2e-30 106.6 0.3 4.4e-30 104.8 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAM28059.1 - 1.3e-17 65.0 0.2 1.3e-17 65.0 0.2 6.4 3 2 1 6 6 6 1 AAA domain AAA_29 PF13555.6 GAM28059.1 - 7.7e-05 22.4 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 GAM28059.1 - 0.0013 18.6 0.1 0.0013 18.6 0.1 3.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GAM28059.1 - 0.14 12.4 1.4 0.36 11.1 0.0 2.5 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 GAM28059.1 - 0.84 8.2 69.1 0.35 9.5 17.3 5.3 3 2 1 5 5 5 0 AAA domain MukB PF04310.12 GAM28059.1 - 3.7 7.3 6.6 28 4.4 0.0 3.6 2 1 1 3 3 3 0 MukB N-terminal bZIP_1 PF00170.21 GAM28059.1 - 5.1 7.3 26.4 0.14 12.2 4.3 5.9 5 0 0 5 5 5 0 bZIP transcription factor DUF3439 PF11921.8 GAM28059.1 - 8.7 6.3 14.9 47 4.0 10.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CDC45 PF02724.14 GAM28060.1 - 0.35 9.1 2.6 4.9 5.3 0.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF755 PF05501.11 GAM28060.1 - 2 8.7 11.5 3.2 8.0 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) NYD-SP12_N PF15015.6 GAM28060.1 - 2.9 6.1 6.3 4.4 5.5 6.3 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Dicty_CTDC PF00526.18 GAM28061.1 - 1.3e-21 76.2 152.8 2.2e-05 24.2 1.2 13.1 13 2 0 13 13 13 9 Dictyostelium (slime mold) repeat PA14 PF07691.12 GAM28061.1 - 3.2e-10 40.0 1.1 6.7e-10 38.9 0.2 1.8 2 0 0 2 2 2 1 PA14 domain Corona_NSP4_C PF16348.5 GAM28061.1 - 0.05 14.4 1.2 0.47 11.3 0.6 2.3 2 0 0 2 2 2 0 Coronavirus nonstructural protein 4 C-terminus Integrin_b_cyt PF08725.11 GAM28061.1 - 0.52 10.0 3.5 1 9.1 3.5 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain MMS1_N PF10433.9 GAM28062.1 - 3.3e-99 332.7 0.6 5.1e-99 332.1 0.1 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAM28062.1 - 4.2e-68 230.0 0.5 1.4e-66 225.0 0.0 2.8 3 0 0 3 3 3 1 CPSF A subunit region PBD PF00786.28 GAM28063.1 - 1.1e-16 60.9 0.0 2.4e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain WH1 PF00568.23 GAM28063.1 - 1.5e-16 60.3 0.3 2.1e-16 59.8 0.3 1.2 1 0 0 1 1 1 1 WH1 domain DCP1 PF06058.13 GAM28063.1 - 1.9e-05 24.6 0.8 2.8e-05 24.0 0.8 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family WH2 PF02205.20 GAM28063.1 - 0.021 14.6 0.2 0.042 13.7 0.2 1.5 1 0 0 1 1 1 0 WH2 motif Macoilin PF09726.9 GAM28063.1 - 1.2 7.6 7.5 1.5 7.3 7.5 1.1 1 0 0 1 1 1 0 Macoilin family GCS PF03074.16 GAM28064.1 - 1.6e-164 547.6 0.7 2.1e-164 547.2 0.7 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Fungal_TACC PF12709.7 GAM28065.1 - 0.33 11.4 2.1 0.54 10.7 0.8 2.0 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins RelB_leu_zip PF16180.5 GAM28066.1 - 0.024 14.6 0.1 8.8 6.4 0.0 2.4 2 0 0 2 2 2 0 RelB leucine zipper ATP-synt_ab PF00006.25 GAM28067.1 - 1.4e-45 155.5 0.0 3.8e-45 154.1 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 GAM28067.1 - 1.4e-30 105.6 0.0 3.6e-30 104.3 0.0 1.7 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 GAM28067.1 - 1e-08 35.6 0.7 2.6e-08 34.3 0.5 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF2118 PF09891.9 GAM28067.1 - 0.0043 17.0 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) TbpB_B_D PF01298.18 GAM28068.1 - 0.00066 20.1 2.0 0.00082 19.8 2.0 1.1 1 0 0 1 1 1 1 C-lobe and N-lobe beta barrels of Tf-binding protein B DUF2367 PF10164.9 GAM28068.1 - 0.79 10.2 4.2 1.7 9.2 4.2 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Cation_ATPase_N PF00690.26 GAM28071.1 - 3.1e-13 49.2 0.0 5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 GAM28072.1 - 3.5e-19 69.0 0.1 5.5e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase E1-E2_ATPase PF00122.20 GAM28073.1 - 0.098 12.2 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 E1-E2 ATPase Inhibitor_I29 PF08246.12 GAM28074.1 - 2.7e-14 53.3 2.9 5.5e-14 52.3 2.9 1.5 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) PDDEXK_2 PF12784.7 GAM28074.1 - 0.098 12.2 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase Nucleopor_Nup85 PF07575.13 GAM28074.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin VSP PF03302.13 GAM28074.1 - 1.4 7.7 3.8 2 7.2 3.8 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Peptidase_C1 PF00112.23 GAM28075.1 - 5e-43 147.7 3.5 8.7e-43 146.9 3.5 1.3 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 GAM28075.1 - 7.4e-09 36.5 4.5 1.7e-08 35.4 4.5 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_C39_2 PF13529.6 GAM28075.1 - 0.00046 20.8 0.0 0.0012 19.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C1_2 PF03051.15 GAM28075.1 - 0.0025 16.7 1.5 0.089 11.6 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DnaJ PF00226.31 GAM28076.1 - 1.9e-18 66.3 5.1 2.1e-18 66.2 0.3 3.4 3 1 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.31 GAM28076.1 - 6e-18 64.8 1.5 1.1e-07 31.9 0.4 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Zip PF02535.22 GAM28076.1 - 4 6.6 3.8 8.2 5.5 3.8 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter CoA_binding PF02629.19 GAM28077.1 - 6.8e-30 103.6 2.0 9e-30 103.2 1.0 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 GAM28077.1 - 3.4e-22 78.9 0.1 5.8e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 GAM28077.1 - 1.1e-09 38.2 0.0 2.4e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GAM28077.1 - 0.053 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain BRK PF07533.16 GAM28077.1 - 0.17 11.5 0.1 16 5.2 0.0 2.6 2 0 0 2 2 2 0 BRK domain Aminotran_1_2 PF00155.21 GAM28078.1 - 2e-73 247.7 0.0 3.2e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAM28078.1 - 1.8e-05 23.5 0.0 3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAM28078.1 - 7.5e-05 21.8 0.0 0.00025 20.1 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Flagellin_N PF00669.20 GAM28078.1 - 0.065 13.3 1.1 0.16 12.1 1.1 1.6 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Ras PF00071.22 GAM28079.1 - 6.2e-59 198.2 0.1 7.2e-59 198.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM28079.1 - 6.6e-33 113.5 0.0 9.5e-33 113.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM28079.1 - 1e-12 47.8 0.1 1.2e-12 47.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM28079.1 - 2.4e-07 30.8 0.0 4.9e-07 29.8 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM28079.1 - 2e-05 24.2 0.1 0.0015 18.1 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAM28079.1 - 5.1e-05 22.7 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAM28079.1 - 0.00037 20.4 0.2 0.019 14.9 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 GAM28079.1 - 0.0016 18.2 0.1 0.1 12.4 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 GAM28079.1 - 0.0023 17.5 0.1 0.0087 15.7 0.0 1.8 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 GAM28079.1 - 0.0048 16.4 0.1 0.0078 15.7 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 GAM28079.1 - 0.006 16.9 0.0 0.015 15.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 GAM28079.1 - 0.0079 16.0 0.3 0.3 10.8 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 GAM28079.1 - 0.018 14.3 0.2 0.094 12.0 0.1 2.0 2 0 0 2 2 2 0 Septin SRPRB PF09439.10 GAM28079.1 - 0.034 13.6 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 GAM28079.1 - 0.049 13.0 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 GAM28079.1 - 0.06 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 GAM28079.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM28079.1 - 0.076 13.4 0.0 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 GAM28079.1 - 0.096 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NTPase DAP3 PF10236.9 GAM28079.1 - 0.1 11.8 0.2 0.14 11.3 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.22 GAM28079.1 - 0.1 11.8 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 GAM28079.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAM28079.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 GAM28079.1 - 0.21 10.7 0.8 0.62 9.2 0.3 1.9 1 1 0 2 2 2 0 G-protein alpha subunit 3Beta_HSD PF01073.19 GAM28080.1 - 3.8e-75 252.5 0.0 5.1e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAM28080.1 - 3e-36 125.1 0.0 3.8e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAM28080.1 - 4.3e-18 65.8 0.1 6e-15 55.5 0.1 2.5 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAM28080.1 - 6.2e-14 51.8 0.2 2.8e-09 36.5 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GAM28080.1 - 2e-12 47.4 0.0 2.8e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAM28080.1 - 2.3e-11 43.3 0.0 2.7e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAM28080.1 - 2.2e-07 30.3 0.0 7.5e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAM28080.1 - 3.1e-05 24.0 0.7 0.035 14.0 0.3 2.4 1 1 1 2 2 2 2 KR domain NmrA PF05368.13 GAM28080.1 - 0.032 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family FNIP PF05725.12 GAM28081.1 - 2.1e-24 85.4 12.0 1e-05 25.6 0.3 11.1 9 3 2 11 11 11 9 FNIP Repeat F-box PF00646.33 GAM28081.1 - 0.37 10.7 3.2 1.2 9.0 3.2 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 GAM28081.1 - 0.43 10.5 3.5 1.3 9.0 3.5 1.8 1 0 0 1 1 1 0 F-box-like SNF2_N PF00176.23 GAM28082.1 - 1.3e-76 257.6 0.0 1.3e-76 257.6 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM28082.1 - 2.8e-18 66.3 0.0 7.6e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 GAM28082.1 - 3.8e-08 33.1 3.7 3.8e-08 33.1 3.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM28082.1 - 1.3e-06 28.3 8.7 1.3e-06 28.3 8.7 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAM28082.1 - 1.3e-06 28.2 8.8 1.3e-06 28.2 8.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAM28082.1 - 2.7e-05 23.9 2.9 2.7e-05 23.9 2.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM28082.1 - 0.00015 21.6 6.7 0.00015 21.6 6.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAM28082.1 - 0.00017 21.6 6.6 0.00017 21.6 6.6 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GAM28082.1 - 0.0006 20.1 5.9 0.0006 20.1 5.9 2.6 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 GAM28082.1 - 0.0011 18.8 3.1 0.0011 18.8 3.1 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 GAM28082.1 - 0.11 12.2 6.0 0.28 11.0 6.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger Blt1 PF12754.7 GAM28082.1 - 0.16 12.3 3.8 0.15 12.4 0.8 2.7 2 0 0 2 2 1 0 Blt1 N-terminal domain zf-rbx1 PF12678.7 GAM28082.1 - 1.4 9.3 4.6 0.58 10.5 0.4 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain BASP1 PF05466.12 GAM28082.1 - 3.7 7.5 7.8 9.8 6.1 7.8 1.7 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) zf-RING_10 PF16685.5 GAM28082.1 - 4.2 7.6 6.7 0.6 10.3 1.5 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-Nse PF11789.8 GAM28082.1 - 6.9 6.6 11.1 0.23 11.3 3.7 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RhoGAP PF00620.27 GAM28083.1 - 5.4e-34 117.2 1.3 7.1e-34 116.8 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain Kelch_4 PF13418.6 GAM28083.1 - 4.1e-27 93.9 2.3 3.3e-12 46.2 0.0 5.1 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM28083.1 - 4e-25 86.8 0.2 2.2e-07 30.6 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 GAM28083.1 - 5.2e-24 83.6 0.2 3e-08 33.1 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 GAM28083.1 - 5.5e-22 77.2 1.7 3.6e-08 33.4 0.0 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.6 GAM28083.1 - 1.3e-20 72.9 0.2 5.5e-09 35.8 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAM28083.1 - 1.4e-18 66.7 10.6 4.1e-12 46.1 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain PNISR PF15996.5 GAM28083.1 - 0.029 14.6 12.3 0.091 13.0 12.3 1.8 1 1 0 1 1 1 0 Arginine/serine-rich protein PNISR TGF_beta_GS PF08515.12 GAM28083.1 - 0.059 12.9 0.2 0.19 11.2 0.2 1.9 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif RhoGAP PF00620.27 GAM28084.1 - 3.7e-35 121.0 3.8 4.4e-33 114.3 0.3 2.8 3 0 0 3 3 3 2 RhoGAP domain Ca_bind_SSO6904 PF18249.1 GAM28084.1 - 0.056 13.8 0.1 0.21 11.9 0.1 2.0 1 0 0 1 1 1 0 Calcium binding protein SSO6904 YfmQ PF10787.9 GAM28084.1 - 0.22 11.3 1.6 26 4.6 0.1 3.0 2 0 0 2 2 2 0 Uncharacterised protein from bacillus cereus group IMD PF08397.11 GAM28084.1 - 1.6 8.0 5.1 0.21 10.9 0.2 2.1 3 0 0 3 3 3 0 IRSp53/MIM homology domain DEAD PF00270.29 GAM28085.1 - 6.9e-50 169.2 0.0 1e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM28085.1 - 2e-32 111.9 0.0 1.2e-31 109.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM28085.1 - 3.8e-05 23.8 0.0 7.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_25 PF13649.6 GAM28086.1 - 1.9e-19 70.2 0.0 2.4e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM28086.1 - 2.5e-18 66.4 0.0 3.2e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM28086.1 - 3.8e-17 62.7 0.0 5.1e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM28086.1 - 3.7e-15 56.0 0.0 4.3e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM28086.1 - 1.5e-13 51.3 0.0 2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM28086.1 - 8.4e-11 41.6 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.16 GAM28086.1 - 1.7e-07 30.7 0.4 5.4e-06 25.7 0.4 2.0 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_PK PF05891.12 GAM28086.1 - 1.8e-05 24.4 0.0 2.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_9 PF08003.11 GAM28086.1 - 4.2e-05 22.6 0.0 4.9e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 GAM28086.1 - 0.00025 20.6 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 GAM28086.1 - 0.00043 19.9 0.0 0.00053 19.7 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 GAM28086.1 - 0.00066 19.1 0.0 0.00081 18.8 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 GAM28086.1 - 0.003 17.0 0.0 0.004 16.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 GAM28086.1 - 0.016 14.5 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 GAM28086.1 - 0.019 15.1 0.1 0.086 12.9 0.1 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 GAM28086.1 - 0.058 11.9 0.0 0.074 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 GAM28086.1 - 0.074 12.1 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_7 PF03492.15 GAM28086.1 - 0.08 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Cons_hypoth95 PF03602.15 GAM28086.1 - 0.1 12.2 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Peptidase_M48 PF01435.18 GAM28087.1 - 1.1e-34 119.9 0.7 2.1e-34 119.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M48 Androgen_recep PF02166.16 GAM28087.1 - 0.0096 14.8 1.5 0.0096 14.8 1.5 2.0 2 0 0 2 2 2 1 Androgen receptor Pkinase PF00069.25 GAM28088.1 - 2.1e-51 174.8 0.1 2.1e-51 174.8 0.1 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28088.1 - 4e-30 105.0 0.9 7.1e-30 104.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 GAM28088.1 - 0.053 13.4 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family GalP_UDP_transf PF01087.22 GAM28088.1 - 0.27 11.7 6.9 0.47 10.9 5.1 2.2 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, N-terminal domain MACPF PF01823.19 GAM28091.1 - 6.3e-24 85.2 0.4 9e-24 84.7 0.4 1.2 1 0 0 1 1 1 1 MAC/Perforin domain RabGAP-TBC PF00566.18 GAM28092.1 - 1.7e-42 145.5 9.7 1.7e-42 145.5 9.7 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 GAM28092.1 - 6.2e-21 74.6 2.7 5.8e-18 64.9 2.7 2.7 1 1 0 1 1 1 1 Rab-binding domain (RBD) Phosducin PF02114.16 GAM28093.1 - 3.3e-15 55.8 0.8 4.2e-15 55.4 0.8 1.1 1 0 0 1 1 1 1 Phosducin WD40 PF00400.32 GAM28094.1 - 1.8e-19 69.7 11.8 8.7e-09 35.9 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM28094.1 - 1.8e-08 34.6 4.3 0.054 13.8 0.1 4.5 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GAM28094.1 - 0.029 14.0 0.0 7.9 6.0 0.0 3.4 1 1 2 3 3 3 0 PQQ-like domain SSP160 PF06933.11 GAM28094.1 - 1.5 7.0 14.1 2 6.5 14.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CRAL_TRIO PF00650.20 GAM28095.1 - 2.1e-42 144.5 0.1 3.2e-42 144.0 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM28095.1 - 1.5e-10 41.1 3.4 4.1e-10 39.7 3.4 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAM28095.1 - 3.3e-07 30.6 0.0 4.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PP2C PF00481.21 GAM28097.1 - 4.4e-46 157.6 1.6 6.8e-46 157.0 0.0 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C DUF4482 PF14818.6 GAM28097.1 - 0.0014 19.5 4.8 0.0014 19.5 4.8 2.9 3 1 1 4 4 4 1 Domain of unknown function (DUF4482) DUF3048_C PF17479.2 GAM28097.1 - 0.045 14.1 0.1 0.79 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain Wzy_C PF04932.15 GAM28097.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 O-Antigen ligase PhoU PF01895.19 GAM28097.1 - 0.15 12.5 0.5 34 5.0 0.2 2.8 2 0 0 2 2 2 0 PhoU domain APC_N_CC PF16689.5 GAM28097.1 - 0.36 10.9 7.8 0.12 12.4 4.1 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain JIP_LZII PF16471.5 GAM28097.1 - 6 7.1 14.0 0.093 12.9 4.7 2.6 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF724 PF05266.14 GAM28097.1 - 7.3 6.4 18.1 0.33 10.8 9.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Ion_trans PF00520.31 GAM28098.1 - 4e-34 118.0 70.9 5.7e-22 78.1 37.8 2.2 2 0 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 GAM28098.1 - 2.5e-05 24.6 2.3 2.8e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GAM28098.1 - 6.4e-05 22.2 0.2 0.011 15.2 0.3 3.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GAM28098.1 - 0.0057 16.5 10.2 0.046 13.7 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GAM28098.1 - 0.013 15.3 0.2 0.046 13.6 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain pair GRP PF07172.11 GAM28098.1 - 0.016 15.9 5.6 0.016 15.9 5.6 3.2 2 0 0 2 2 2 0 Glycine rich protein family HA2 PF04408.23 GAM28098.1 - 4.2 7.7 6.5 1.3e+02 2.9 0.0 3.0 2 0 0 2 2 2 0 Helicase associated domain (HA2) La PF05383.17 GAM28099.1 - 8e-20 70.7 0.1 1.3e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 GAM28099.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 GAM28100.1 - 5.5e-41 139.9 0.1 5.5e-41 139.9 0.1 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 GAM28100.1 - 1e-20 74.1 0.6 7.9e-20 71.3 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM28100.1 - 1.6e-05 24.4 0.6 2.5e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM28100.1 - 0.003 17.6 0.2 0.0083 16.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 GAM28100.1 - 0.04 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain THEG4 PF15834.5 GAM28100.1 - 0.18 11.8 2.3 0.3 11.0 2.3 1.3 1 0 0 1 1 1 0 Testis highly expressed protein 4 Bac_export_2 PF01312.19 GAM28100.1 - 0.33 10.1 3.6 0.49 9.6 3.6 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family FKBP_C PF00254.28 GAM28101.1 - 1.3e-29 102.4 0.0 1.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Actin PF00022.19 GAM28102.1 - 2.3e-57 194.5 0.3 7.3e-32 110.5 0.0 2.3 2 0 0 2 2 2 2 Actin PDDEXK_1 PF12705.7 GAM28103.1 - 3.6e-05 23.8 0.1 8.5e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 GAM28103.1 - 0.049 13.7 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF83 GBR_NSP5 PF17580.2 GAM28103.1 - 0.099 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 ABC_membrane PF00664.23 GAM28104.1 - 6.5e-130 432.7 23.6 8.4e-65 219.1 9.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM28104.1 - 1.5e-69 232.8 0.2 6.6e-34 117.4 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM28104.1 - 2.4e-15 56.6 1.7 1.1e-05 25.0 0.0 4.0 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 GAM28104.1 - 7.1e-07 28.4 0.5 0.019 13.7 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 GAM28104.1 - 4.2e-05 23.2 1.8 0.14 11.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 GAM28104.1 - 0.00014 22.0 2.6 0.64 10.3 0.2 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 GAM28104.1 - 0.00014 21.7 0.0 0.45 10.2 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAM28104.1 - 0.00036 20.5 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAM28104.1 - 0.00077 19.9 0.1 0.48 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 GAM28104.1 - 0.0017 18.2 1.7 12 5.6 0.1 4.1 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAM28104.1 - 0.0018 18.6 3.0 2 8.7 0.3 3.9 3 2 0 3 3 3 2 AAA domain AAA_18 PF13238.6 GAM28104.1 - 0.0023 18.5 0.2 4.9 7.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 GAM28104.1 - 0.0027 17.0 2.1 0.76 9.0 0.0 3.0 4 0 0 4 4 4 2 Zeta toxin RuvX PF03652.15 GAM28104.1 - 0.0062 16.9 0.4 0.53 10.7 0.1 2.7 2 0 0 2 2 2 1 Holliday junction resolvase AAA_30 PF13604.6 GAM28104.1 - 0.016 14.9 0.3 6.1 6.5 0.1 3.4 2 2 0 2 2 2 0 AAA domain PRK PF00485.18 GAM28104.1 - 0.02 14.6 0.0 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 GAM28104.1 - 0.021 14.0 0.1 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 GAM28104.1 - 0.054 13.2 0.1 7.3 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAM28104.1 - 0.12 11.9 0.0 9.8 5.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 GAM28104.1 - 0.17 11.9 1.3 37 4.3 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 GAM28104.1 - 0.22 10.4 1.8 12 4.7 0.1 2.8 3 0 0 3 3 3 0 AAA-like domain DUF87 PF01935.17 GAM28104.1 - 0.29 11.2 1.8 31 4.6 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain Vps54_N PF10475.9 GAM28105.1 - 7.3e-88 294.6 7.7 1.7e-87 293.4 7.7 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 GAM28105.1 - 1.6e-54 185.1 3.2 2.7e-54 184.4 0.2 2.8 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 GAM28105.1 - 0.0015 18.4 5.1 0.002 18.0 2.4 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Mating_N PF12731.7 GAM28105.1 - 0.011 15.8 2.9 0.079 13.1 0.0 3.4 3 0 0 3 3 3 0 Mating-type protein beta 1 Vps51 PF08700.11 GAM28105.1 - 0.02 15.0 0.1 0.074 13.1 0.1 2.0 1 0 0 1 1 1 0 Vps51/Vps67 COG2 PF06148.11 GAM28105.1 - 0.037 14.1 0.3 0.037 14.1 0.3 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 VGLL4 PF15245.6 GAM28105.1 - 0.09 12.8 1.9 20 5.1 0.5 3.3 3 0 0 3 3 3 0 Transcription cofactor vestigial-like protein 4 Vps54 PF07928.12 GAM28105.1 - 0.95 9.9 6.5 0.75 10.2 0.2 3.6 4 0 0 4 4 4 0 Vps54-like protein DNA_pol_A_exo1 PF01612.20 GAM28106.1 - 5e-17 62.2 0.0 7.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DUF1160 PF06648.11 GAM28106.1 - 0.017 15.1 0.1 0.032 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) V_ATPase_I PF01496.19 GAM28107.1 - 9.7e-296 983.0 7.6 1.8e-295 982.1 7.6 1.4 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DASH_Dam1 PF08653.10 GAM28107.1 - 0.012 15.5 1.3 3.7 7.4 0.5 3.9 3 1 0 3 3 3 0 DASH complex subunit Dam1 Cep57_MT_bd PF06657.13 GAM28107.1 - 0.11 13.0 5.2 0.12 12.8 1.9 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 CorA PF01544.18 GAM28107.1 - 0.16 11.3 3.2 0.32 10.2 3.2 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Rootletin PF15035.6 GAM28107.1 - 0.29 11.1 7.5 0.56 10.2 7.5 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FapA PF03961.13 GAM28107.1 - 0.29 9.7 4.0 0.48 9.0 4.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 GAM28107.1 - 0.32 11.5 8.2 0.8 10.2 8.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region FPP PF05911.11 GAM28107.1 - 0.49 8.5 12.4 0.059 11.6 7.6 1.7 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil FlaC_arch PF05377.11 GAM28107.1 - 0.59 10.6 9.6 0.066 13.6 2.8 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 GAM28107.1 - 0.67 9.5 4.8 0.52 9.8 2.9 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF641 PF04859.12 GAM28107.1 - 0.74 10.2 4.9 1.4 9.3 4.9 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Herpes_UL14 PF03580.14 GAM28107.1 - 0.78 10.0 4.3 1.6 9.0 4.3 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein ABC_tran_CTD PF16326.5 GAM28107.1 - 0.93 9.8 7.2 0.2 11.9 1.1 2.7 3 0 0 3 3 3 0 ABC transporter C-terminal domain MutS_III PF05192.18 GAM28107.1 - 8.8 6.5 6.4 19 5.4 6.3 1.4 1 1 0 1 1 1 0 MutS domain III MIG-14_Wnt-bd PF06664.12 GAM28108.1 - 2.8e-55 187.6 29.0 4.4e-55 187.0 29.0 1.2 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion TrmO PF01980.16 GAM28109.1 - 5.6e-42 142.7 0.0 1.2e-41 141.7 0.0 1.6 1 0 0 1 1 1 1 tRNA-methyltransferase O DnaJ_C PF01556.18 GAM28110.1 - 1.4e-39 135.6 0.9 1.9e-39 135.1 0.9 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAM28110.1 - 1.4e-27 95.6 1.5 2.4e-27 94.8 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAM28110.1 - 4.8e-16 58.9 18.6 8.5e-16 58.1 18.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAM28110.1 - 0.0052 16.7 14.7 0.013 15.4 1.0 3.0 2 1 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 GAM28110.1 - 0.0056 16.7 6.9 0.61 10.1 0.4 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CLASP_N PF12348.8 GAM28111.1 - 1.9e-28 99.6 1.4 5.6e-28 98.1 0.2 2.1 2 0 0 2 2 2 1 CLASP N terminal Spectrin PF00435.21 GAM28111.1 - 0.027 14.9 0.1 0.21 12.1 0.0 2.5 1 1 0 1 1 1 0 Spectrin repeat DUF1664 PF07889.12 GAM28111.1 - 1.2 9.2 3.7 1.2 9.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 GAM28112.1 - 2.9e-303 1007.9 0.2 4.9e-303 1007.2 0.2 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF641 PF04859.12 GAM28112.1 - 0.5 10.7 4.3 1 9.7 4.3 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) FTA4 PF13093.6 GAM28112.1 - 0.56 10.1 6.3 0.13 12.1 2.8 1.6 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Occludin_ELL PF07303.13 GAM28112.1 - 7.4 7.4 8.9 4.8 8.0 0.9 3.2 3 0 0 3 3 3 0 Occludin homology domain DUF2236 PF09995.9 GAM28113.1 - 3e-06 27.6 0.0 4.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3290 PF11694.8 GAM28113.1 - 0.073 13.1 0.2 0.88 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) TIR_2 PF13676.6 GAM28114.1 - 1.3e-20 74.2 0.2 2e-18 67.1 0.1 2.8 2 0 0 2 2 2 1 TIR domain Ank_2 PF12796.7 GAM28114.1 - 2.9e-17 63.0 1.5 9.2e-12 45.4 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM28114.1 - 6.5e-15 55.0 0.2 1.5e-10 41.1 0.0 4.5 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM28114.1 - 1.5e-14 54.2 1.1 5.5e-09 36.4 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) RCC1_2 PF13540.6 GAM28114.1 - 2.4e-13 49.5 14.5 1.5e-07 31.0 4.1 3.9 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 GAM28114.1 - 3.3e-12 46.8 2.7 1.1e-05 25.9 0.2 4.1 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.6 GAM28114.1 - 6.9e-12 44.5 0.1 0.00018 21.7 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 GAM28114.1 - 3.4e-10 39.9 0.6 0.0002 21.6 0.0 4.3 5 0 0 5 5 4 3 Ankyrin repeat TIR PF01582.20 GAM28114.1 - 9.2e-06 25.6 0.0 2.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 GAM28114.1 - 0.00035 20.9 2.0 0.025 14.9 1.9 3.5 4 1 0 4 4 4 1 MTH538 TIR-like domain (DUF1863) BRCT_2 PF16589.5 GAM28114.1 - 0.0028 18.0 0.0 0.0079 16.6 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Vezatin PF12632.7 GAM28115.1 - 1.9e-07 30.8 13.0 2.3e-06 27.2 13.0 2.2 1 1 0 1 1 1 1 Mysoin-binding motif of peroxisomes NOA36 PF06524.12 GAM28115.1 - 0.0052 16.2 13.3 0.0052 16.2 13.3 1.7 2 0 0 2 2 2 1 NOA36 protein DUF4611 PF15387.6 GAM28115.1 - 0.017 15.3 16.6 0.056 13.7 10.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 GAM28115.1 - 0.052 13.9 24.6 0.094 13.1 17.9 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 GAM28115.1 - 0.34 10.9 13.4 0.15 12.0 8.6 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Utp14 PF04615.13 GAM28115.1 - 0.59 8.6 8.9 0.069 11.7 4.3 1.7 2 0 0 2 2 2 0 Utp14 protein SDA1 PF05285.12 GAM28115.1 - 1.3 8.3 11.2 0.062 12.7 5.4 1.7 2 0 0 2 2 2 0 SDA1 Cwf_Cwc_15 PF04889.12 GAM28115.1 - 1.5 8.5 23.8 0.14 11.9 16.6 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.10 GAM28115.1 - 2.7 8.3 7.2 0.8 10.0 3.5 2.1 2 1 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 YL1 PF05764.13 GAM28115.1 - 7.6 6.6 12.4 1 9.4 7.4 2.1 2 0 0 2 2 2 0 YL1 nuclear protein RNA_pol_3_Rpc31 PF11705.8 GAM28115.1 - 9.6 6.4 15.4 6 7.1 12.9 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PseudoU_synth_1 PF01416.20 GAM28116.1 - 1.4e-27 96.3 0.0 4.7e-26 91.4 0.0 2.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase Arf PF00025.21 GAM28118.1 - 2.9e-76 254.8 0.1 3.3e-76 254.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM28118.1 - 5.3e-15 55.7 0.0 7.4e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM28118.1 - 1.8e-14 53.6 0.0 2.2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAM28118.1 - 3.4e-13 49.5 1.5 2.5e-09 36.8 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GAM28118.1 - 2.9e-12 46.5 0.0 3.3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAM28118.1 - 8.9e-12 44.8 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM28118.1 - 1.6e-05 25.0 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAM28118.1 - 0.0013 18.1 0.9 0.0054 16.1 0.9 2.1 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Cep57_CLD PF14073.6 GAM28119.1 - 0.017 15.1 2.2 0.017 15.1 2.2 2.3 3 0 0 3 3 3 0 Centrosome localisation domain of Cep57 Ank_3 PF13606.6 GAM28120.1 - 0.07 13.7 0.3 1.1e+02 3.9 0.0 4.6 4 0 0 4 4 4 0 Ankyrin repeat SAM_Exu PF18609.1 GAM28120.1 - 0.089 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Exuperantia SAM-like domain SLT_2 PF13406.6 GAM28122.1 - 0.034 13.4 1.3 0.64 9.2 0.3 2.1 2 0 0 2 2 2 0 Transglycosylase SLT domain Flagellin_C PF00700.21 GAM28122.1 - 0.081 13.3 3.4 0.27 11.6 2.5 2.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region AAT PF03417.16 GAM28123.1 - 0.014 15.1 0.7 0.033 13.9 0.7 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase CRC_subunit PF08624.10 GAM28123.1 - 0.07 13.6 0.0 0.57 10.6 0.0 2.3 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit PIN_8 PF18476.1 GAM28123.1 - 0.089 12.6 5.9 0.83 9.5 2.3 2.3 2 0 0 2 2 2 0 PIN like domain Spectrin PF00435.21 GAM28123.1 - 8.6 6.9 8.9 0.81 10.2 0.6 3.4 2 2 2 4 4 4 0 Spectrin repeat Asp_protease_2 PF13650.6 GAM28124.1 - 3.3e-06 27.7 0.7 1.1e-05 25.9 0.0 2.1 2 1 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GAM28124.1 - 0.00074 19.8 0.1 0.00074 19.8 0.1 2.4 2 1 1 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GAM28124.1 - 0.001 19.6 0.2 0.001 19.6 0.2 2.7 2 2 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GAM28124.1 - 0.0032 17.2 0.7 0.0072 16.1 0.7 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Macoilin PF09726.9 GAM28124.1 - 7.5 5.0 16.0 9.2 4.7 16.0 1.1 1 0 0 1 1 1 0 Macoilin family CENP-B_dimeris PF09026.10 GAM28125.1 - 0.0099 16.3 2.1 0.012 15.9 2.1 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain CDC45 PF02724.14 GAM28125.1 - 0.99 7.6 8.2 0.97 7.6 8.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GAM28125.1 - 1.7 7.1 9.7 1.8 7.0 9.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.6 GAM28125.1 - 8.4 6.8 13.7 2.5 8.5 10.3 1.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PLDc_2 PF13091.6 GAM28126.1 - 4.5e-22 78.4 0.4 2.3e-16 59.9 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAM28126.1 - 7.1e-06 26.0 0.7 0.042 14.0 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Ribosomal_L9_N PF01281.19 GAM28127.1 - 1.5e-16 59.7 0.0 4.9e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 GAM28127.1 - 0.00017 22.0 0.1 0.00029 21.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Peptidase_C54 PF03416.19 GAM28128.1 - 1e-94 317.1 0.0 1.3e-94 316.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 GAM28128.1 - 0.004 16.7 0.1 0.0094 15.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase family C78 ADP_PFK_GK PF04587.15 GAM28129.1 - 1.1e-130 436.1 0.2 1.3e-130 435.8 0.2 1.0 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Nitro_FeMo-Co PF02579.17 GAM28129.1 - 0.031 14.6 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor PfkB PF00294.24 GAM28129.1 - 0.15 11.3 0.1 0.36 10.1 0.1 1.6 1 1 0 1 1 1 0 pfkB family carbohydrate kinase PDEase_II PF02112.15 GAM28130.1 - 2.9e-83 279.8 1.1 3.6e-83 279.5 1.1 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II LRR_6 PF13516.6 GAM28131.1 - 8.9e-06 25.4 44.7 0.022 14.8 0.0 11.8 13 0 0 13 13 13 3 Leucine Rich repeat LRR_8 PF13855.6 GAM28131.1 - 8.4e-05 22.3 28.5 0.35 10.7 0.1 8.0 6 3 0 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 GAM28131.1 - 0.001 19.4 39.5 0.2 12.2 0.2 8.8 5 4 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM28131.1 - 0.004 17.5 31.1 18 6.4 0.0 11.7 10 2 0 10 10 10 2 Leucine Rich Repeat Carm_PH PF17888.1 GAM28131.1 - 0.03 14.7 0.0 0.074 13.4 0.0 1.6 1 0 0 1 1 1 0 Carmil pleckstrin homology domain ABC_tran PF00005.27 GAM28132.1 - 5.2e-43 146.8 3.7 8.6e-21 74.9 0.0 3.4 4 0 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 GAM28132.1 - 7e-14 52.3 7.1 0.0037 17.1 0.5 4.4 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAM28132.1 - 2.6e-07 31.2 1.0 0.0059 17.0 0.0 3.2 4 0 0 4 4 2 2 AAA ATPase domain ABC_tran_Xtn PF12848.7 GAM28132.1 - 2.7e-07 30.5 3.7 2.7e-07 30.5 3.7 3.4 3 1 1 4 4 4 1 ABC transporter NACHT PF05729.12 GAM28132.1 - 6.4e-07 29.4 0.2 0.022 14.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 GAM28132.1 - 6.4e-07 29.9 0.1 0.028 14.9 0.1 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 GAM28132.1 - 8.3e-07 28.7 1.3 0.019 14.4 0.2 3.5 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAM28132.1 - 1.1e-06 28.6 1.4 0.051 13.3 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 GAM28132.1 - 5.2e-06 27.0 5.5 0.3 11.6 0.0 4.6 5 0 0 5 5 4 2 AAA domain RsgA_GTPase PF03193.16 GAM28132.1 - 9.7e-06 25.6 0.6 0.062 13.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 GAM28132.1 - 1e-05 26.2 9.6 0.022 15.3 0.0 3.9 5 0 0 5 5 3 2 AAA domain AAA_29 PF13555.6 GAM28132.1 - 2e-05 24.2 0.3 0.11 12.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAM28132.1 - 2.6e-05 24.5 0.0 0.37 11.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 GAM28132.1 - 2.7e-05 24.2 2.5 0.049 13.7 0.3 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 GAM28132.1 - 6.5e-05 23.2 7.0 0.091 13.0 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 GAM28132.1 - 8.6e-05 22.6 0.2 1 9.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 GAM28132.1 - 0.0001 22.1 0.0 0.63 9.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAM28132.1 - 0.0001 22.3 0.0 1.2 9.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 GAM28132.1 - 0.00012 21.9 0.7 0.43 10.3 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.6 GAM28132.1 - 0.00016 21.8 5.2 0.036 14.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 GAM28132.1 - 0.00019 21.0 0.1 0.44 10.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 GAM28132.1 - 0.0002 21.0 0.0 0.3 10.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 GAM28132.1 - 0.0002 21.5 0.6 0.6 10.3 0.1 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 GAM28132.1 - 0.00042 20.2 0.4 0.29 11.0 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 GAM28132.1 - 0.00051 19.3 0.1 0.96 8.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.22 GAM28132.1 - 0.00053 20.3 0.0 0.4 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase cobW PF02492.19 GAM28132.1 - 0.00054 19.6 0.9 0.42 10.2 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 GAM28132.1 - 0.00055 19.7 2.5 0.52 10.0 0.1 3.2 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 GAM28132.1 - 0.00077 19.4 0.2 0.27 11.1 0.0 2.7 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 GAM28132.1 - 0.0016 18.5 0.2 1.8 8.6 0.1 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 GAM28132.1 - 0.0016 18.4 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea DUF3584 PF12128.8 GAM28132.1 - 0.0041 14.7 0.1 0.0041 14.7 0.1 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF3584) FeoB_N PF02421.18 GAM28132.1 - 0.0042 16.6 0.4 1.3 8.5 0.1 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_19 PF13245.6 GAM28132.1 - 0.0045 17.3 0.1 3.7 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 GAM28132.1 - 0.01 15.5 2.1 1.3 8.6 0.1 2.7 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_13 PF13166.6 GAM28132.1 - 0.025 13.2 7.2 0.13 10.9 0.2 3.2 2 1 1 3 3 3 0 AAA domain T2SSE PF00437.20 GAM28132.1 - 0.035 13.2 0.1 6.1 5.8 0.2 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein PWI PF01480.17 GAM28132.1 - 0.054 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 PWI domain Pox_A32 PF04665.12 GAM28132.1 - 0.13 11.6 1.8 2.8 7.4 0.1 3.1 3 0 0 3 3 3 0 Poxvirus A32 protein ATP-synt_ab PF00006.25 GAM28132.1 - 0.2 11.3 0.0 8.7 5.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 GAM28132.1 - 0.35 10.9 10.1 0.98 9.5 0.1 4.0 3 1 1 4 4 4 0 Helicase HerA, central domain Zeta_toxin PF06414.12 GAM28132.1 - 0.43 9.8 3.7 6.9 5.9 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin Acetyltransf_9 PF13527.7 GAM28133.1 - 4e-25 88.4 0.1 6.9e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM28133.1 - 9.5e-08 32.3 0.0 4e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAM28133.1 - 4.6e-06 27.0 0.0 4.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM28133.1 - 0.0003 20.7 0.3 0.0013 18.7 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAM28133.1 - 0.013 15.0 0.2 0.022 14.2 0.2 1.4 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 GAM28133.1 - 0.021 15.0 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 GAM28133.1 - 0.029 14.4 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 GAM28133.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Redoxin PF08534.10 GAM28134.1 - 7.4e-31 106.8 0.0 7.9e-31 106.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAM28134.1 - 1e-10 41.6 0.0 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF824 PF05688.11 GAM28134.1 - 0.078 12.8 0.0 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) Rap_GAP PF02145.15 GAM28135.1 - 2.6e-47 160.8 0.0 5.5e-47 159.7 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Toxin_25 PF08095.11 GAM28135.1 - 0.34 10.9 1.7 1.1 9.3 1.7 1.8 1 0 0 1 1 1 0 Hefutoxin family Kinesin PF00225.23 GAM28136.1 - 1.7e-107 359.2 0.1 1.7e-107 359.2 0.1 2.9 3 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 GAM28136.1 - 1.3e-26 93.3 0.5 9.3e-26 90.5 0.0 2.8 2 0 0 2 2 2 1 Microtubule binding WD40 PF00400.32 GAM28136.1 - 2.4e-24 85.1 20.8 3e-05 24.7 0.7 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM28136.1 - 0.088 13.1 0.1 42 4.5 0.0 3.3 1 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 GAM28137.1 - 1e-11 43.5 2.3 2.4e-05 23.5 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAM28137.1 - 1.1e-09 38.6 0.2 2e-09 37.8 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM28137.1 - 1.3e-07 30.9 1.0 0.00011 21.8 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 GAM28137.1 - 5.4e-05 22.9 0.8 0.00011 22.0 0.8 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GAM28137.1 - 0.01 15.3 0.3 0.58 9.8 0.0 2.5 2 0 0 2 2 2 0 EF hand Dockerin_1 PF00404.18 GAM28137.1 - 0.11 12.7 0.1 0.64 10.3 0.1 2.1 1 1 1 2 2 2 0 Dockerin type I domain TMA7 PF09072.10 GAM28138.1 - 4.2e-27 94.8 22.2 4.6e-27 94.6 22.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 PBP PF01161.20 GAM28139.1 - 6.7e-17 62.0 0.3 8.5e-17 61.7 0.3 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GDPD PF03009.17 GAM28140.1 - 8.8e-57 192.8 0.0 2e-56 191.6 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_4 PF13637.6 GAM28140.1 - 7.8e-38 128.4 1.3 7.7e-08 32.7 0.0 6.5 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM28140.1 - 5.4e-35 119.8 9.2 9.4e-11 42.2 0.1 5.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM28140.1 - 1.1e-26 92.5 0.7 2.3e-06 27.7 0.0 6.7 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28140.1 - 1.1e-22 77.6 0.7 0.00066 19.9 0.0 8.0 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 GAM28140.1 - 1.5e-21 75.8 0.1 0.00022 21.5 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat CBM_20 PF00686.19 GAM28140.1 - 3.2e-16 59.0 0.0 7.4e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain SPX PF03105.19 GAM28140.1 - 0.00015 21.9 5.1 0.25 11.2 0.3 3.4 1 1 1 3 3 3 2 SPX domain UQ_con PF00179.26 GAM28141.1 - 4.6e-09 36.1 0.0 7.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SR-25 PF10500.9 GAM28141.1 - 0.11 12.1 9.7 0.15 11.6 9.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein N_BRCA1_IG PF16158.5 GAM28142.1 - 2.3e-29 102.1 0.0 5.9e-29 100.8 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 GAM28142.1 - 3.4e-16 58.9 0.1 5.4e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.17 GAM28142.1 - 4.6e-12 45.5 5.7 1.1e-11 44.4 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 GAM28142.1 - 0.00067 19.9 6.6 0.0016 18.7 6.6 1.6 1 0 0 1 1 1 1 C1 domain DUF1043 PF06295.12 GAM28142.1 - 7.9 6.5 7.2 3.3 7.7 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) PNP_UDP_1 PF01048.20 GAM28144.1 - 2e-29 102.5 0.2 2.4e-29 102.2 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily ERCC4 PF02732.15 GAM28145.1 - 1.9e-18 67.1 0.5 9.2e-18 64.9 0.0 2.5 3 0 0 3 3 3 1 ERCC4 domain LRR_4 PF12799.7 GAM28146.1 - 5.4e-36 122.0 44.0 2.5e-09 37.3 2.4 7.5 4 1 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM28146.1 - 9.6e-26 89.3 34.9 3.5e-09 36.3 5.8 5.4 2 1 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 GAM28146.1 - 5.3e-23 81.4 27.4 4e-09 36.2 0.9 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 GAM28146.1 - 3.5e-08 32.9 20.9 0.11 12.7 0.1 8.3 7 1 1 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 GAM28146.1 - 3.1e-05 23.9 31.3 7.4 7.5 0.0 10.7 10 2 0 10 10 10 3 Leucine Rich Repeat LRR_2 PF07723.13 GAM28146.1 - 0.028 15.1 2.1 1.1e+02 3.7 0.1 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat E2F_TDP PF02319.20 GAM28147.1 - 8.5e-17 61.0 0.4 9.8e-08 31.9 0.2 2.8 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Proteasome PF00227.26 GAM28148.1 - 2.5e-61 206.5 0.2 4.7e-61 205.6 0.2 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM28148.1 - 2.3e-09 36.8 0.1 1.6e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DRMBL PF07522.14 GAM28149.1 - 3e-26 91.8 0.1 7.4e-26 90.5 0.1 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 GAM28149.1 - 0.00028 20.5 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAM28149.1 - 0.016 15.3 0.3 0.03 14.3 0.3 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily RMMBL PF07521.12 GAM28149.1 - 0.028 14.4 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Utp14 PF04615.13 GAM28149.1 - 2.6 6.5 14.1 4.9 5.6 14.1 1.4 1 0 0 1 1 1 0 Utp14 protein CBM49 PF09478.10 GAM28150.1 - 8.8e-07 29.1 1.4 1.1e-06 28.8 0.3 1.7 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 MRP-L27 PF09809.9 GAM28151.1 - 5.9e-10 39.0 0.1 6.3e-10 38.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 PH PF00169.29 GAM28152.1 - 3.5e-13 50.0 2.7 1.5e-11 44.7 2.7 2.8 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM28152.1 - 3.8e-06 27.1 0.4 0.071 13.4 0.1 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 GAM28152.1 - 0.00018 21.5 1.1 1.8 8.7 0.4 4.0 3 1 1 4 4 4 2 PH domain PH_11 PF15413.6 GAM28152.1 - 0.0026 18.2 6.6 0.0026 18.2 6.6 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain DUF1016_N PF17761.1 GAM28152.1 - 0.033 14.4 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 DUF1016 N-terminal domain YejG PF13989.6 GAM28153.1 - 0.043 14.3 0.0 0.071 13.6 0.0 1.4 1 1 0 1 1 1 0 YejG-like protein Ank_5 PF13857.6 GAM28155.1 - 0.0077 16.5 0.0 13 6.2 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM28155.1 - 0.017 15.7 2.1 0.88 10.2 0.0 3.7 4 1 0 4 4 4 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM28155.1 - 0.038 14.5 0.3 14 6.6 0.0 4.6 5 0 0 5 5 5 0 Ankyrin repeat DUF3447 PF11929.8 GAM28155.1 - 0.23 11.4 3.8 5.4 7.1 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3447) SdrD_B PF17210.3 GAM28156.1 - 2.7e-06 27.6 1.8 0.0078 16.4 0.3 2.3 2 0 0 2 2 2 2 SdrD B-like domain SdrD_B PF17210.3 GAM28157.1 - 8.7e-07 29.2 31.0 1.7e-05 25.0 3.4 5.6 5 1 0 5 5 5 2 SdrD B-like domain Y_Y_Y PF07495.13 GAM28157.1 - 0.00048 20.0 5.4 0.99 9.4 0.2 3.7 3 0 0 3 3 3 2 Y_Y_Y domain Colipase PF01114.18 GAM28157.1 - 0.24 11.1 1.6 7.7 6.3 0.0 3.1 4 0 0 4 4 4 0 Colipase, N-terminal domain CBM60 PF16841.5 GAM28157.1 - 0.6 10.6 5.2 1.5 9.3 0.4 3.3 3 0 0 3 3 3 0 Ca-dependent carbohydrate-binding module xylan-binding SpaA PF17802.1 GAM28157.1 - 8.6 6.8 17.1 0.93 9.9 0.4 4.2 3 1 1 4 4 4 0 Prealbumin-like fold domain Ank_2 PF12796.7 GAM28158.1 - 5.6e-15 55.7 43.1 0.28 11.8 0.0 16.8 13 6 4 17 17 17 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28158.1 - 2.7e-06 27.8 25.0 0.38 11.4 0.0 13.5 14 2 2 16 16 16 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM28158.1 - 1.1e-05 25.6 15.0 1.3 9.5 0.0 10.4 14 1 1 15 15 15 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28158.1 - 8.9e-05 22.6 27.8 0.16 12.6 0.2 13.8 15 0 0 15 15 15 1 Ankyrin repeat Phage_T7_Capsid PF05396.11 GAM28158.1 - 0.00043 20.6 2.6 0.21 11.9 0.1 4.4 4 0 0 4 4 4 1 Phage T7 capsid assembly protein Glyco_hydro_18 PF00704.28 GAM28159.1 - 1.8e-49 169.2 0.7 3.2e-49 168.4 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 GAM28159.1 - 1.4e-10 41.1 0.0 4.1e-06 26.8 0.0 3.6 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 GAM28159.1 - 3.9e-07 30.4 13.2 3.9e-07 30.4 13.2 3.6 4 0 0 4 4 4 1 Chitin recognition protein Sial-lect-inser PF09264.10 GAM28159.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion FNIP PF05725.12 GAM28162.1 - 2.1e-59 197.4 9.6 4.9e-17 61.8 0.0 7.1 2 2 5 8 8 8 8 FNIP Repeat Glyco_hydro_18 PF00704.28 GAM28163.1 - 1.9e-64 218.4 4.4 2.5e-64 218.0 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4232 PF14016.6 GAM28163.1 - 0.0082 16.3 0.2 0.045 13.9 0.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4232) DUF5523 PF17661.1 GAM28166.1 - 0.0023 17.7 4.2 0.0026 17.5 4.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5523) Spt20 PF12090.8 GAM28166.1 - 0.0047 16.6 16.3 0.0052 16.4 16.3 1.3 1 0 0 1 1 1 1 Spt20 family Band_3_cyto PF07565.13 GAM28166.1 - 0.02 14.7 4.5 0.022 14.6 4.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TFIIA PF03153.13 GAM28166.1 - 0.063 13.3 20.3 0.063 13.3 20.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 GAM28166.1 - 0.11 13.2 14.0 0.14 12.8 14.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 GAM28166.1 - 0.46 11.5 4.8 0.63 11.0 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 GAM28166.1 - 0.59 10.2 4.5 0.67 10.0 4.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 GAM28166.1 - 0.75 8.5 5.5 0.93 8.2 5.5 1.1 1 0 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.8 GAM28166.1 - 7.1 5.5 35.0 9 5.1 35.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4175 PF13779.6 GAM28166.1 - 7.4 4.3 19.8 8.9 4.1 19.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3464 PF11947.8 GAM28166.1 - 9.2 6.0 8.2 13 5.5 8.2 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TBCA PF02970.16 GAM28167.1 - 4.7e-23 81.3 10.7 6.5e-23 80.9 10.7 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A FapA PF03961.13 GAM28167.1 - 0.1 11.2 7.2 0.12 11.0 7.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3552 PF12072.8 GAM28167.1 - 0.31 10.4 9.6 0.38 10.2 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FlxA PF14282.6 GAM28167.1 - 0.94 9.5 5.6 0.23 11.5 0.8 1.9 1 1 1 2 2 2 0 FlxA-like protein EMC3_TMCO1 PF01956.16 GAM28167.1 - 3 7.6 4.5 9.8 5.9 4.5 1.8 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Spb1_C PF07780.12 GAM28168.1 - 1.6e-62 210.9 26.0 1.6e-62 210.9 26.0 4.1 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 GAM28168.1 - 2.5e-55 187.3 0.0 4.7e-55 186.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 GAM28168.1 - 1.5e-36 125.7 17.2 1.5e-36 125.7 17.2 6.2 2 1 2 4 4 4 1 Domain of unknown function (DUF3381) Methyltr_RsmB-F PF01189.17 GAM28168.1 - 0.013 15.1 0.1 0.14 11.8 0.0 2.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Cellulase-like PF12876.7 GAM28169.1 - 0.066 12.6 0.0 0.077 12.3 0.0 1.1 1 0 0 1 1 1 0 Sugar-binding cellulase-like Agenet PF05641.12 GAM28170.1 - 0.0017 18.7 1.1 0.15 12.5 0.3 3.2 3 0 0 3 3 3 1 Agenet domain DASH_Dad3 PF08656.10 GAM28170.1 - 0.22 11.7 0.2 0.48 10.5 0.2 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad3 Peptidase_C48 PF02902.19 GAM28173.1 - 0.0003 20.7 0.0 0.00084 19.2 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Bul1_C PF04426.12 GAM28174.1 - 0.00082 18.9 1.6 0.0011 18.4 1.2 1.4 1 1 0 1 1 1 1 Bul1 C terminus RGI1 PF10843.8 GAM28174.1 - 0.027 14.1 0.3 0.04 13.6 0.3 1.3 1 0 0 1 1 1 0 Respiratory growth induced protein 1 ALMT PF11744.8 GAM28174.1 - 0.046 12.6 4.7 0.059 12.2 4.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Eco57I PF07669.11 GAM28174.1 - 0.055 14.0 0.5 0.11 13.0 0.5 1.5 1 0 0 1 1 1 0 Eco57I restriction-modification methylase CRISPR_Cas2 PF09827.9 GAM28176.1 - 0.0076 16.4 0.2 0.04 14.1 0.0 2.1 3 0 0 3 3 3 1 CRISPR associated protein Cas2 DUF2457 PF10446.9 GAM28176.1 - 0.7 9.0 9.7 0.8 8.8 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 GAM28176.1 - 4.3 6.6 9.1 5.7 6.2 9.1 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_B_2 PF03175.13 GAM28177.1 - 5.6e-06 25.5 0.9 8.4e-05 21.6 0.9 2.1 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Ank_2 PF12796.7 GAM28178.1 - 1e-11 45.2 8.5 0.00034 21.1 0.0 5.4 6 1 0 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM28178.1 - 7.3e-06 25.9 13.2 2 9.3 0.3 8.0 8 0 0 8 8 8 1 Ankyrin repeat Ank_4 PF13637.6 GAM28178.1 - 0.0022 18.6 8.4 17 6.2 0.2 6.4 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM28178.1 - 0.031 14.6 10.5 17 5.9 0.1 6.8 6 2 1 7 7 7 0 Ankyrin repeats (many copies) Ank PF00023.30 GAM28178.1 - 0.42 11.1 10.6 29 5.3 1.2 5.3 4 1 1 5 5 5 0 Ankyrin repeat DUF3447 PF11929.8 GAM28178.1 - 9 6.3 15.0 19 5.3 0.2 6.4 7 1 1 8 8 8 0 Domain of unknown function (DUF3447) UAF_Rrn10 PF05234.11 GAM28179.1 - 0.097 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 UAF complex subunit Rrn10 Ank_2 PF12796.7 GAM28180.1 - 1e-09 38.8 24.1 0.0093 16.5 2.8 10.0 9 2 1 10 10 10 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM28180.1 - 0.00091 19.5 13.6 44 5.1 0.0 10.1 12 0 0 12 12 12 1 Ankyrin repeat Ank_4 PF13637.6 GAM28180.1 - 0.0049 17.4 8.6 85 3.9 0.1 8.0 8 0 0 8 8 8 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM28180.1 - 0.0074 16.6 12.6 22 5.5 0.6 8.3 8 1 1 9 9 9 1 Ankyrin repeats (many copies) TPR_12 PF13424.6 GAM28181.1 - 2.7e-09 37.2 0.5 0.11 12.8 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM28181.1 - 9.4e-09 35.7 0.1 3.5 8.2 0.0 5.9 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAM28181.1 - 2.2e-07 31.1 0.0 6.8 7.8 0.0 7.6 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM28181.1 - 5.9e-07 29.4 0.0 1 9.9 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM28181.1 - 6.7e-06 25.7 0.0 0.048 13.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM28181.1 - 8.6e-06 25.5 0.1 1.1 9.6 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAM28181.1 - 0.0002 20.8 0.7 0.007 15.8 0.1 3.1 4 0 0 4 4 4 1 MalT-like TPR region ANAPC3 PF12895.7 GAM28181.1 - 0.0014 18.8 0.1 7.4 6.9 0.0 4.2 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAM28181.1 - 0.0074 16.4 0.0 9.3 6.8 0.0 5.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAM28181.1 - 0.021 15.4 2.0 51 4.8 0.0 6.3 9 0 0 9 9 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAM28181.1 - 0.026 15.1 0.0 60 4.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAM28181.1 - 0.11 12.4 0.0 20 5.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_9 PF13901.6 GAM28181.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Pox_A_type_inc PF04508.12 GAM28182.1 - 0.044 13.6 5.6 0.16 11.9 0.1 3.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF3333 PF11812.8 GAM28182.1 - 0.64 10.2 5.7 0.099 12.8 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) MMR_HSR1_C PF08438.10 GAM28183.1 - 2.9e-36 124.4 0.1 4.6e-36 123.8 0.1 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 GAM28183.1 - 6.7e-22 77.7 0.0 2.3e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM28183.1 - 1.7e-10 40.7 0.4 1.4e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B YchF-GTPase_C PF06071.13 GAM28183.1 - 0.0037 17.4 0.0 0.0095 16.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) TGS PF02824.21 GAM28183.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 TGS domain Dynamin_N PF00350.23 GAM28183.1 - 0.028 14.5 0.0 0.083 12.9 0.0 1.8 1 0 0 1 1 1 0 Dynamin family MMR_HSR1_Xtn PF16897.5 GAM28183.1 - 0.039 14.0 0.1 0.086 12.9 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 GAM28183.1 - 0.16 11.9 0.3 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase PTP_tm PF18861.1 GAM28185.1 - 0.0056 16.7 0.1 0.0056 16.7 0.1 1.9 3 0 0 3 3 3 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Adeno_E3_CR2 PF02439.15 GAM28186.1 - 0.0053 16.5 1.8 0.011 15.5 1.8 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Beta_helix PF13229.6 GAM28186.1 - 0.033 14.1 51.7 0.037 13.9 24.8 3.4 1 1 2 3 3 3 0 Right handed beta helix region Syndecan PF01034.20 GAM28186.1 - 0.13 12.1 1.1 0.27 11.2 1.1 1.4 1 0 0 1 1 1 0 Syndecan domain Ank_4 PF13637.6 GAM28187.1 - 0.015 15.9 0.9 10 6.8 0.0 5.2 4 1 0 4 4 4 0 Ankyrin repeats (many copies) ABC2_membrane_3 PF12698.7 GAM28187.1 - 0.028 13.6 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein Ank_3 PF13606.6 GAM28187.1 - 0.046 14.3 0.2 2.4e+02 2.9 0.1 5.5 4 0 0 4 4 4 0 Ankyrin repeat DUF3870 PF12986.7 GAM28187.1 - 0.13 12.5 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3870) DUF1539 PF07560.11 GAM28187.1 - 3.9 7.6 9.0 11 6.1 0.2 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Ank_4 PF13637.6 GAM28188.1 - 0.019 15.5 3.1 1.2e+02 3.5 0.0 6.5 7 0 0 7 7 7 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28188.1 - 0.067 13.8 0.0 6.8 7.6 0.0 4.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 GAM28189.1 - 2.2e-17 63.4 22.7 0.031 14.8 0.0 12.6 11 3 1 13 13 13 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28189.1 - 4.3e-07 30.3 17.3 13 6.5 0.0 12.9 13 2 1 14 14 14 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM28189.1 - 3.4e-05 24.0 3.3 17 5.9 0.0 9.1 11 1 1 12 12 12 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28189.1 - 0.096 13.3 26.5 1.2e+02 3.8 0.0 15.5 21 0 0 21 21 21 0 Ankyrin repeat CHIPS PF11434.8 GAM28190.1 - 0.049 13.5 0.1 0.16 11.8 0.1 1.9 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS CHZ PF09649.10 GAM28190.1 - 0.18 11.3 0.5 5.6 6.5 0.2 2.4 2 0 0 2 2 2 0 Histone chaperone domain CHZ DUF3447 PF11929.8 GAM28190.1 - 1 9.4 4.7 6 6.9 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) DDE_Tnp_4 PF13359.6 GAM28191.1 - 2.8e-23 82.3 0.4 7.7e-22 77.6 0.4 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM28191.1 - 2e-08 34.1 2.0 3.4e-08 33.4 2.0 1.4 1 1 0 1 1 1 1 Transposase DDE domain Ank_2 PF12796.7 GAM28192.1 - 1.3e-07 32.1 2.7 0.0017 18.9 0.2 3.7 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28192.1 - 0.00017 22.0 3.2 10 6.9 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28192.1 - 0.00028 21.1 3.1 14 6.6 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat DUF3734 PF12536.8 GAM28192.1 - 0.0076 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Patatin phospholipase DUF835 PF05763.12 GAM28195.1 - 0.023 14.4 0.1 0.037 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF835) Ank_2 PF12796.7 GAM28196.1 - 0.0048 17.5 0.9 0.94 10.1 0.3 3.0 1 1 1 3 3 3 1 Ankyrin repeats (3 copies) DUF1572 PF07609.11 GAM28196.1 - 0.099 12.4 0.1 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) DUF2222 PF09984.9 GAM28197.1 - 0.0063 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) Ank_2 PF12796.7 GAM28198.1 - 3.3e-09 37.2 1.6 1.1 9.9 0.0 5.4 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM28198.1 - 0.004 17.4 0.0 68 4.0 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28198.1 - 0.12 13.1 1.3 1.2e+02 3.8 0.1 5.6 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 GAM28199.1 - 8.2e-07 29.5 14.1 0.082 13.5 0.1 8.5 6 2 4 10 10 10 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28199.1 - 0.00042 20.8 7.7 7.6 7.2 0.0 7.9 7 1 1 8 8 8 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM28199.1 - 0.0095 16.2 5.4 3.1 8.2 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28199.1 - 1.1 10.0 12.2 4.8e+02 1.9 0.0 8.9 10 0 0 10 10 10 0 Ankyrin repeat Ank_4 PF13637.6 GAM28200.1 - 0.097 13.3 0.2 1.7 9.3 0.1 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM28201.1 - 1.3e-08 35.3 16.4 0.59 10.8 0.0 7.0 5 2 1 7 7 7 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM28201.1 - 3.1e-07 30.5 0.4 7.4 7.0 0.0 7.5 7 1 1 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28201.1 - 3.9e-05 23.7 10.5 7.6 7.5 0.0 9.5 9 1 0 9 9 9 1 Ankyrin repeat Ank_4 PF13637.6 GAM28201.1 - 0.024 15.2 5.6 14 6.4 0.0 6.1 6 1 2 8 8 8 0 Ankyrin repeats (many copies) DUF3447 PF11929.8 GAM28201.1 - 3.2 7.8 18.9 1.5 8.9 0.5 5.7 6 2 0 6 6 6 0 Domain of unknown function (DUF3447) Ank PF00023.30 GAM28201.1 - 5.2 7.7 10.2 3.8e+02 1.8 0.1 7.0 8 0 0 8 8 8 0 Ankyrin repeat Ank_2 PF12796.7 GAM28202.1 - 1.2e-05 25.8 0.4 0.31 11.7 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM28202.1 - 0.0024 18.2 2.4 51 4.9 0.0 6.2 8 0 0 8 8 8 0 Ankyrin repeat Ank_4 PF13637.6 GAM28202.1 - 0.021 15.4 0.8 7.1 7.3 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM28202.1 - 0.066 13.6 0.2 16 6.0 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeats (many copies) DUF4611 PF15387.6 GAM28202.1 - 2.9 8.2 7.8 29 5.0 3.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Ank_3 PF13606.6 GAM28203.1 - 0.016 15.7 0.3 11 7.0 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 GAM28203.1 - 0.018 15.6 0.4 0.53 10.9 0.2 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28203.1 - 0.081 13.5 0.1 4.4 8.0 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) GoLoco PF02188.17 GAM28203.1 - 0.28 10.7 0.0 0.28 10.7 0.0 2.1 3 0 0 3 3 3 0 GoLoco motif Ank_3 PF13606.6 GAM28205.1 - 0.0013 19.1 13.0 28 5.7 0.0 10.3 12 0 0 12 12 12 1 Ankyrin repeat TGS PF02824.21 GAM28205.1 - 0.014 15.4 0.4 0.044 13.8 0.1 2.1 2 0 0 2 2 2 0 TGS domain Ank_5 PF13857.6 GAM28205.1 - 0.021 15.2 2.9 36 4.8 0.0 6.4 8 1 0 8 8 8 0 Ankyrin repeats (many copies) DUF87 PF01935.17 GAM28205.1 - 0.11 12.5 4.8 7.4 6.6 0.7 3.5 3 0 0 3 3 3 0 Helicase HerA, central domain Ank_4 PF13637.6 GAM28205.1 - 0.36 11.5 9.9 1.6e+02 3.0 0.0 8.3 10 1 2 12 12 12 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM28206.1 - 0.0048 17.4 0.6 7.5 7.3 0.0 3.7 3 2 1 4 4 4 1 Ankyrin repeats (many copies) HTH_46 PF15977.5 GAM28206.1 - 0.017 15.1 0.2 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding DUF1652 PF07865.11 GAM28206.1 - 0.027 14.3 0.1 0.073 12.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) Ank_2 PF12796.7 GAM28207.1 - 0.00026 21.5 0.0 0.01 16.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM28207.1 - 0.00046 20.4 0.0 1.8 9.4 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat FdhE PF04216.12 GAM28207.1 - 0.055 13.3 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation SAP18 PF06487.12 GAM28207.1 - 0.075 13.2 0.7 0.89 9.7 0.2 2.4 1 1 1 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) BTB PF00651.31 GAM28207.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain DUF758 PF05527.11 GAM28210.1 - 5.7e-35 120.9 0.9 9.3e-35 120.2 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF758) PH PF00169.29 GAM28210.1 - 1.4e-10 41.6 0.0 3.2e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 GAM28210.1 - 0.0027 18.1 1.0 0.1 13.0 0.7 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Histone_H2A_C PF16211.5 GAM28211.1 - 0.00088 19.0 0.0 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 C-terminus of histone H2A TAF PF02969.17 GAM28211.1 - 0.0033 17.6 0.1 0.0095 16.1 0.1 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 GAM28211.1 - 0.015 15.7 0.8 3 8.2 0.3 2.3 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 MCM_lid PF17855.1 GAM28211.1 - 0.2 12.1 0.3 0.2 12.1 0.3 2.0 2 1 0 2 2 2 0 MCM AAA-lid domain KELK PF15796.5 GAM28211.1 - 0.34 11.4 4.1 0.16 12.5 1.0 2.0 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Peptidase_M24 PF00557.24 GAM28212.1 - 1.1e-39 136.3 0.3 1.8e-39 135.6 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 GAM28212.1 - 2.1e-21 75.8 0.0 5.1e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 GAM28212.1 - 5e-18 66.0 0.1 2.1e-16 60.8 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Creatinase_N_2 PF16189.5 GAM28212.1 - 2.7e-11 43.8 0.0 4.1e-10 40.0 0.0 2.5 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain KinB_sensor PF16767.5 GAM28212.1 - 0.022 15.2 0.2 0.68 10.4 0.0 2.7 2 1 1 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF4980 PF16352.5 GAM28212.1 - 0.039 14.0 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4980) LigB PF02900.18 GAM28213.1 - 1.9e-36 125.5 0.1 2.3e-36 125.3 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase GCP_C_terminal PF04130.13 GAM28214.1 - 1.9e-77 260.8 17.8 1.9e-77 260.8 17.8 2.9 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAM28214.1 - 4.7e-73 246.5 2.3 4.7e-73 246.5 2.3 2.4 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal SR-25 PF10500.9 GAM28214.1 - 0.0027 17.4 10.7 0.0027 17.4 10.7 3.6 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein Kelch_6 PF13964.6 GAM28215.1 - 3.2e-08 33.6 5.2 0.017 15.4 0.1 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 GAM28215.1 - 4.1e-06 26.7 5.6 0.011 15.7 0.0 3.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM28215.1 - 2.1e-05 24.3 1.4 0.13 12.3 0.0 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 GAM28215.1 - 0.00013 21.5 2.1 0.26 10.9 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 GAM28215.1 - 0.0015 18.7 0.6 1.8 8.9 0.0 4.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM28215.1 - 0.0047 16.9 4.3 0.66 10.0 0.1 3.3 3 0 0 3 3 3 2 Kelch motif DnaI_N PF07319.11 GAM28215.1 - 0.017 15.7 4.4 0.26 12.0 2.2 3.2 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus HAUS2 PF15003.6 GAM28215.1 - 0.22 11.3 2.7 0.26 11.0 1.8 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 2 Kelch_6 PF13964.6 GAM28216.1 - 9e-10 38.5 8.6 1.1e-05 25.5 0.0 4.3 5 0 0 5 5 4 2 Kelch motif Kelch_4 PF13418.6 GAM28216.1 - 1.9e-07 31.0 3.6 4.8e-05 23.3 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM28216.1 - 2.6e-06 26.9 5.8 0.00038 20.0 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 GAM28216.1 - 2.8e-06 27.5 0.1 0.022 15.0 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM28216.1 - 0.00031 20.6 0.1 0.34 10.9 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 GAM28216.1 - 0.0031 17.5 5.7 0.82 9.7 0.9 2.7 2 0 0 2 2 2 2 Kelch motif Ran-binding PF05508.11 GAM28216.1 - 0.0043 16.1 0.1 0.0073 15.3 0.1 1.3 1 0 0 1 1 1 1 RanGTP-binding protein Baculo_PEP_C PF04513.12 GAM28216.1 - 0.029 14.4 0.2 0.094 12.8 0.2 1.8 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 GAM28216.1 - 0.035 14.2 3.5 0.089 12.9 1.6 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Nop14 PF04147.12 GAM28216.1 - 0.036 12.3 1.2 0.048 11.9 1.2 1.1 1 0 0 1 1 1 0 Nop14-like family PhoU_div PF01865.16 GAM28216.1 - 0.043 13.2 0.2 0.074 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF47 Syntaxin-6_N PF09177.11 GAM28216.1 - 0.065 13.8 0.1 0.25 11.9 0.1 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Globin PF00042.22 GAM28216.1 - 0.14 12.8 0.1 0.43 11.2 0.0 1.8 2 0 0 2 2 1 0 Globin ALS_ss_C PF10369.9 GAM28216.1 - 0.22 11.8 1.1 2 8.7 0.0 2.7 3 0 0 3 3 3 0 Small subunit of acetolactate synthase Syntaxin_2 PF14523.6 GAM28216.1 - 5.1 7.5 11.0 3.6e+02 1.6 8.6 3.6 3 1 0 3 3 3 0 Syntaxin-like protein zf-B_box PF00643.24 GAM28216.1 - 8.8 6.6 6.4 0.81 9.9 1.5 1.9 2 0 0 2 2 1 0 B-box zinc finger LXG PF04740.12 GAM28217.1 - 0.037 13.7 0.9 0.055 13.2 0.9 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily eIF_4G1 PF12152.8 GAM28217.1 - 0.09 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 DUF1664 PF07889.12 GAM28218.1 - 0.0022 18.0 2.9 0.0086 16.1 0.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF948 PF06103.11 GAM28218.1 - 0.018 15.3 4.3 0.33 11.2 0.1 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HisKA_3 PF07730.13 GAM28218.1 - 0.033 14.7 1.0 0.73 10.4 0.6 2.4 1 1 1 2 2 2 0 Histidine kinase Muted PF14942.6 GAM28218.1 - 0.033 14.5 1.4 0.033 14.5 1.4 2.5 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein L31 PF09784.9 GAM28218.1 - 0.057 13.8 1.6 0.087 13.3 0.2 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 DUF883 PF05957.13 GAM28218.1 - 0.082 13.5 9.2 0.18 12.4 5.2 2.8 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 GAM28218.1 - 0.58 8.0 4.3 0.52 8.2 0.6 1.7 1 1 1 2 2 2 0 Prominin YtxH PF12732.7 GAM28218.1 - 1 10.0 14.0 74 4.0 12.2 3.6 1 1 0 1 1 1 0 YtxH-like protein DUF4698 PF15769.5 GAM28218.1 - 1.4 7.9 14.3 0.19 10.8 10.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4698) PRKCSH-like PF12999.7 GAM28218.1 - 1.8 8.3 6.8 0.99 9.2 3.1 2.1 1 1 1 2 2 2 0 Glucosidase II beta subunit-like DSS1_SEM1 PF05160.13 GAM28219.1 - 2.9e-13 49.7 24.9 3.7e-13 49.3 24.6 1.3 1 1 0 1 1 1 1 DSS1/SEM1 family DNA_pol_phi PF04931.13 GAM28219.1 - 5.8 4.9 16.5 5.9 4.9 16.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 GAM28220.1 - 2.2e-44 148.6 18.4 1.7e-08 34.9 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM28220.1 - 6.8e-16 58.3 0.1 0.001 19.3 0.1 6.3 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 GAM28220.1 - 4.5e-14 51.7 4.9 1.3e-13 50.3 4.9 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 GAM28220.1 - 0.0002 20.5 5.3 0.55 9.1 0.0 4.5 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PPS_PS PF02006.16 GAM28220.1 - 0.04 13.5 0.0 0.11 12.0 0.1 1.7 2 0 0 2 2 2 0 Phosphopantothenate/pantothenate synthetase Hydin_ADK PF17213.3 GAM28220.1 - 4.2 7.6 6.3 0.47 10.7 0.8 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Pre-PUA PF17832.1 GAM28221.1 - 2.7e-23 82.5 0.0 9.2e-23 80.7 0.0 2.0 1 0 0 1 1 1 1 Pre-PUA-like domain SUI1 PF01253.22 GAM28221.1 - 1.4e-13 51.2 2.2 1.4e-13 51.2 2.2 2.4 2 0 0 2 2 2 1 Translation initiation factor SUI1 YL1 PF05764.13 GAM28221.1 - 3.1e-05 24.2 14.8 6.7e-05 23.1 14.8 1.6 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 GAM28221.1 - 0.0006 18.3 12.6 0.00091 17.7 12.6 1.2 1 0 0 1 1 1 1 CDC45-like protein Ribosomal_L22e PF01776.17 GAM28221.1 - 0.0017 18.7 1.9 0.0051 17.2 1.9 1.8 1 0 0 1 1 1 1 Ribosomal L22e protein family PUA PF01472.20 GAM28221.1 - 0.0045 16.9 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 GAM28221.1 - 0.034 14.4 2.6 0.062 13.6 0.2 2.9 2 1 0 2 2 1 0 Domain of unknown function (DUF1947) Cwf_Cwc_15 PF04889.12 GAM28221.1 - 0.15 11.8 33.3 0.028 14.2 29.3 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GAM28221.1 - 0.36 10.2 32.4 0.77 9.1 32.4 1.5 1 0 0 1 1 1 0 SDA1 DDHD PF02862.17 GAM28221.1 - 0.4 10.8 6.8 0.39 10.8 1.4 2.4 2 0 0 2 2 2 0 DDHD domain SAPS PF04499.15 GAM28221.1 - 0.51 9.1 15.3 0.85 8.3 15.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 GAM28221.1 - 0.83 8.1 19.1 1.4 7.4 19.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Dicty_REP PF05086.12 GAM28221.1 - 1.3 6.9 18.7 2.4 6.0 18.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zip PF02535.22 GAM28221.1 - 1.3 8.2 3.7 2 7.5 3.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2457 PF10446.9 GAM28221.1 - 1.7 7.7 34.2 3 6.9 34.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TERB2 PF15101.6 GAM28221.1 - 3.5 7.6 11.9 1.2 9.2 5.5 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 PNISR PF15996.5 GAM28221.1 - 4 7.7 19.9 9.1 6.5 19.9 1.5 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Nop14 PF04147.12 GAM28221.1 - 6.5 4.8 34.7 12 4.0 34.7 1.3 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 GAM28221.1 - 8.4 5.0 13.1 13 4.4 13.1 1.2 1 0 0 1 1 1 0 Presenilin SUZ PF12752.7 GAM28222.1 - 4.2e-13 49.8 0.4 4.2e-13 49.8 0.4 2.6 2 1 0 2 2 2 1 SUZ domain Pkinase_Tyr PF07714.17 GAM28224.1 - 1e-11 44.6 0.0 1.6e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM28224.1 - 1.3e-10 41.2 0.1 2.4e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 GAM28225.1 - 1.8e-27 96.4 0.0 2.1e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28225.1 - 1e-13 51.2 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Complex1_LYR PF05347.15 GAM28226.1 - 4.7e-12 45.8 0.4 5.5e-12 45.5 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAM28226.1 - 0.0025 18.5 0.1 0.0031 18.2 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 GAM28226.1 - 0.042 14.5 0.1 0.066 13.8 0.1 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Dynamin_M PF01031.20 GAM28227.1 - 6.6e-35 120.7 0.1 6.6e-35 120.7 0.1 2.1 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 GAM28227.1 - 4.5e-19 68.4 4.2 1.3e-18 67.0 4.2 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF2076 PF09849.9 GAM28227.1 - 0.00059 20.0 8.2 0.00083 19.5 8.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Bromodomain PF00439.25 GAM28228.1 - 1.6e-05 24.9 0.0 5.8e-05 23.1 0.0 2.0 1 0 0 1 1 1 1 Bromodomain FHA PF00498.26 GAM28228.1 - 6.6e-05 23.2 0.2 0.00047 20.5 0.0 2.5 2 0 0 2 2 2 1 FHA domain Peptidase_M17 PF00883.21 GAM28229.1 - 1.5e-115 385.8 0.1 1.9e-115 385.4 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 GAM28229.1 - 1.7e-19 69.9 0.1 3.9e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain WHEP-TRS PF00458.20 GAM28229.1 - 0.12 12.5 0.3 0.62 10.3 0.3 2.1 1 1 0 1 1 1 0 WHEP-TRS domain DUF2016 PF09436.10 GAM28229.1 - 0.14 12.0 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) ANAPC16 PF17256.2 GAM28229.1 - 0.16 12.3 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 16 AdoMet_MTase PF07757.13 GAM28230.1 - 1.4e-18 67.3 0.0 2.4e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 GAM28230.1 - 0.0046 17.0 0.4 0.026 14.5 0.0 2.4 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM28230.1 - 0.0073 16.2 0.1 0.05 13.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Mucin PF01456.17 GAM28230.1 - 0.0086 16.1 23.5 0.017 15.1 11.7 2.4 2 0 0 2 2 2 2 Mucin-like glycoprotein Methyltransf_31 PF13847.6 GAM28230.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 GAM28230.1 - 0.13 11.8 0.0 0.36 10.4 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Dicty_REP PF05086.12 GAM28230.1 - 6.2 4.7 13.1 4.4 5.1 3.7 2.2 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Acyl-CoA_dh_1 PF00441.24 GAM28231.1 - 9.7e-27 94.0 0.7 2.7e-26 92.6 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 GAM28231.1 - 2e-23 83.1 0.0 3.2e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAM28231.1 - 2.6e-11 44.0 0.0 1.7e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAM28231.1 - 6.9e-11 42.2 0.0 1.5e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Lipocalin PF00061.23 GAM28232.1 - 0.073 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family DUF2790 PF10976.8 GAM28232.1 - 0.081 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) Ank_4 PF13637.6 GAM28233.1 - 4.5e-36 122.8 15.0 5.8e-06 26.7 0.1 8.7 7 2 1 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM28233.1 - 2.5e-35 120.1 27.5 8.1e-05 22.8 0.1 12.6 2 1 11 13 13 13 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM28233.1 - 1.2e-33 115.5 17.1 2.7e-09 37.5 0.7 5.5 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM28233.1 - 2.7e-20 70.3 12.6 5.9 7.8 0.0 13.1 13 1 1 14 14 14 3 Ankyrin repeat DUF5049 PF16468.5 GAM28233.1 - 2.1e-06 27.5 1.4 10 6.1 0.0 8.8 10 3 3 13 13 13 1 Domain of unknown function (DUF5049) Ank PF00023.30 GAM28233.1 - 2.8e-06 27.5 11.1 35 5.1 0.1 9.9 8 3 4 12 12 12 0 Ankyrin repeat DUF1707 PF08044.11 GAM28233.1 - 0.0019 18.2 6.2 5.8 7.1 0.0 6.5 9 0 0 9 9 9 1 Domain of unknown function (DUF1707) Cas_Csy1 PF09611.10 GAM28233.1 - 0.025 13.7 4.3 1.4 7.9 0.1 3.6 3 2 1 4 4 4 0 CRISPR-associated protein (Cas_Csy1) Bunya_G2 PF03563.13 GAM28233.1 - 0.078 12.2 1.9 2.4 7.3 0.1 3.5 2 2 3 5 5 5 0 Bunyavirus glycoprotein G2 FAD_binding_9 PF08021.11 GAM28233.1 - 0.11 12.7 2.7 2.1 8.6 0.0 3.7 4 0 0 4 4 4 0 Siderophore-interacting FAD-binding domain zf-CCHC_6 PF15288.6 GAM28234.1 - 0.00025 20.8 0.2 0.00044 20.0 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GAM28234.1 - 0.0076 16.3 0.5 0.0076 16.3 0.5 1.7 2 0 0 2 2 2 1 Zinc knuckle PNISR PF15996.5 GAM28234.1 - 1.2 9.3 10.4 1.4 9.1 10.4 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR RNA_polI_A34 PF08208.11 GAM28235.1 - 0.4 10.7 18.9 0.44 10.6 18.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SRP-alpha_N PF04086.13 GAM28235.1 - 0.45 10.4 16.4 0.49 10.3 16.4 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DDRGK PF09756.9 GAM28235.1 - 0.59 9.7 18.0 0.57 9.7 18.0 1.1 1 0 0 1 1 1 0 DDRGK domain Dehydrin PF00257.19 GAM28235.1 - 0.79 10.3 14.9 0.9 10.1 14.9 1.1 1 0 0 1 1 1 0 Dehydrin DUF3439 PF11921.8 GAM28235.1 - 1.3 9.0 10.1 1.3 9.0 9.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) U79_P34 PF03064.16 GAM28235.1 - 3.6 6.9 17.3 4.2 6.7 17.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FAM176 PF14851.6 GAM28235.1 - 3.7 7.2 8.5 4.6 6.9 8.5 1.3 1 0 0 1 1 1 0 FAM176 family NARP1 PF12569.8 GAM28235.1 - 6.2 5.6 14.6 6.4 5.6 14.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.10 GAM28235.1 - 6.4 7.1 19.1 6.8 7.0 19.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Connexin PF00029.19 GAM28235.1 - 9.6 5.9 9.1 10 5.8 9.1 1.1 1 0 0 1 1 1 0 Connexin Proteasome PF00227.26 GAM28236.1 - 3.2e-64 215.9 0.1 3.9e-64 215.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAM28236.1 - 3.1e-13 49.1 0.3 5.6e-13 48.3 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GatB_N PF02934.15 GAM28238.1 - 1.8e-102 342.4 0.0 2.4e-102 342.0 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 GAM28238.1 - 1.1e-41 142.1 0.2 2e-41 141.3 0.2 1.4 1 0 0 1 1 1 1 GatB domain 60KD_IMP PF02096.20 GAM28239.1 - 3.6e-26 92.0 8.3 7.3e-26 91.0 8.3 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein TIG PF01833.24 GAM28240.1 - 2.8e-14 52.9 15.9 3e-08 33.6 0.6 4.3 4 0 0 4 4 4 3 IPT/TIG domain EGF_2 PF07974.13 GAM28240.1 - 0.011 16.0 12.9 0.031 14.7 12.9 1.8 1 0 0 1 1 1 0 EGF-like domain LRR_8 PF13855.6 GAM28240.1 - 0.18 11.6 10.0 0.34 10.7 0.9 3.6 3 0 0 3 3 3 0 Leucine rich repeat Chitin_bind_1 PF00187.19 GAM28240.1 - 0.19 12.2 6.3 0.56 10.7 6.3 1.7 1 0 0 1 1 1 0 Chitin recognition protein Laminin_EGF PF00053.24 GAM28240.1 - 0.7 10.1 7.9 1.9 8.7 7.9 1.7 1 0 0 1 1 1 0 Laminin EGF domain EGF_Tenascin PF18720.1 GAM28240.1 - 8.4 6.6 10.7 22 5.2 10.7 1.8 1 0 0 1 1 1 0 Tenascin EGF domain TIG PF01833.24 GAM28241.1 - 4.4e-20 71.5 20.1 2.9e-08 33.7 2.4 4.6 4 0 0 4 4 4 3 IPT/TIG domain SKG6 PF08693.10 GAM28241.1 - 0.018 14.5 1.5 0.052 13.0 1.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase PF00069.25 GAM28242.1 - 9.5e-74 248.1 0.0 1.4e-73 247.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28242.1 - 1.7e-54 184.9 0.0 3.1e-54 184.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM28242.1 - 3.9e-06 25.9 0.0 1.4e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 GAM28242.1 - 0.00012 21.7 1.5 0.00041 19.9 0.2 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 GAM28242.1 - 0.0084 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Trimer_CC PF08954.11 GAM28242.1 - 0.0088 15.6 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 Trimerisation motif APH PF01636.23 GAM28242.1 - 0.031 14.2 0.0 1.1 9.1 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAM28242.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family SlyX PF04102.12 GAM28242.1 - 0.099 13.3 1.8 0.32 11.6 1.2 2.1 2 0 0 2 2 2 0 SlyX MspA PF09203.11 GAM28242.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 MspA Cep57_MT_bd PF06657.13 GAM28242.1 - 0.17 12.3 3.2 0.19 12.2 0.6 2.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 OmpH PF03938.14 GAM28242.1 - 0.2 12.0 4.4 0.089 13.1 1.8 1.7 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 GAM28242.1 - 0.37 11.1 2.1 2.5 8.5 0.1 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 GAM28242.1 - 0.43 10.9 1.9 1.2 9.4 0.9 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Coiled PF05710.12 GAM28242.1 - 0.78 10.6 9.9 5.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Coiled coil Fib_alpha PF08702.10 GAM28242.1 - 4.4 7.5 6.6 2.8 8.1 0.2 2.5 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Peptidase_M41 PF01434.18 GAM28243.1 - 1e-65 221.2 0.2 1.7e-65 220.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAM28243.1 - 3.5e-44 150.4 0.0 9.3e-44 149.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM28243.1 - 1.7e-12 46.9 0.1 4.1e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAM28243.1 - 0.00046 20.2 0.3 0.0019 18.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM28243.1 - 0.0012 19.1 0.9 0.13 12.5 0.1 3.3 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.6 GAM28243.1 - 0.0013 19.2 0.4 0.012 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAM28243.1 - 0.005 16.6 0.0 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAM28243.1 - 0.0072 16.7 0.1 0.22 11.9 0.1 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 GAM28243.1 - 0.015 15.4 0.2 0.087 12.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 GAM28243.1 - 0.047 13.4 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Csm1_B PF18211.1 GAM28243.1 - 0.062 13.1 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 Csm1 subunit domain B Mg_chelatase PF01078.21 GAM28243.1 - 0.071 12.5 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAM28243.1 - 0.089 13.3 1.5 3.4 8.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.6 GAM28243.1 - 0.79 9.9 3.9 0.68 10.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain SpoIIIAH PF12685.7 GAM28243.1 - 4.3 7.1 11.4 0.056 13.3 1.6 2.7 3 0 0 3 3 3 0 SpoIIIAH-like protein zf-CCHC PF00098.23 GAM28247.1 - 2.1e-07 30.7 4.0 3.8e-07 29.9 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle PRP38_assoc PF12871.7 GAM28247.1 - 0.0096 16.5 22.0 0.0096 16.5 22.0 2.5 3 0 0 3 3 3 2 Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-CCHC_2 PF13696.6 GAM28247.1 - 0.014 15.2 3.7 0.02 14.7 3.7 1.2 1 0 0 1 1 1 0 Zinc knuckle PP2C PF00481.21 GAM28249.1 - 1e-63 215.4 0.0 1e-63 215.4 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Macoilin PF09726.9 GAM28249.1 - 0.25 9.9 7.6 0.27 9.7 7.6 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 GAM28249.1 - 0.94 9.3 8.9 1 9.2 8.9 1.2 1 0 0 1 1 1 0 SPX domain SWI-SNF_Ssr4 PF08549.10 GAM28249.1 - 2.9 6.4 12.4 4.1 5.9 12.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF1387 PF07139.11 GAM28249.1 - 6.5 6.4 11.2 11 5.7 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) EI24 PF07264.11 GAM28250.1 - 1.5e-19 70.9 24.7 2.4e-19 70.3 24.7 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3446 PF11928.8 GAM28250.1 - 6.5 7.1 13.2 4.7 7.6 0.7 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain RRM_5 PF13893.6 GAM28251.1 - 6.9e-44 148.4 2.6 1.2e-25 89.5 0.0 4.3 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 GAM28251.1 - 1.4e-36 124.1 0.0 6.7e-09 35.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 GAM28251.1 - 7.5e-13 48.5 0.0 1.9e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 GAM28251.1 - 1.3e-06 28.2 0.0 0.42 10.5 0.0 4.2 4 0 0 4 4 4 2 Occluded RNA-recognition motif RL PF17797.1 GAM28251.1 - 0.0016 18.3 0.1 1.2 9.1 0.0 3.7 3 1 1 4 4 4 1 RL domain SPX PF03105.19 GAM28251.1 - 0.04 13.8 14.8 1.2 9.0 14.8 2.2 1 1 0 1 1 1 0 SPX domain Chorion_2 PF03964.15 GAM28251.1 - 1.1 10.1 20.8 2.9 8.8 20.8 1.7 1 0 0 1 1 1 0 Chorion family 2 TFIIA PF03153.13 GAM28251.1 - 1.7 8.6 26.0 0.076 13.0 16.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_2 PF13465.6 GAM28253.1 - 2.1 8.9 4.9 75 4.0 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double domain Diphthamide_syn PF01866.17 GAM28254.1 - 1.6e-118 395.6 0.0 2.2e-118 395.2 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF4834 PF16118.5 GAM28254.1 - 6.6 7.8 5.9 3.8 8.5 3.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Pro_isomerase PF00160.21 GAM28255.1 - 6.5e-54 182.5 0.0 1.3e-53 181.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 GAM28255.1 - 4e-06 26.9 0.2 1.2e-05 25.4 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 GAM28255.1 - 1.4e-05 25.1 1.8 0.00023 21.2 0.0 3.1 3 0 0 3 3 3 1 U-box domain Rtf2 PF04641.12 GAM28255.1 - 0.00037 20.0 0.1 0.00037 20.0 0.1 2.7 2 1 0 2 2 2 1 Rtf2 RING-finger Glyco_hydro_77 PF02446.17 GAM28256.1 - 1.5e-157 525.2 2.7 2e-157 524.8 2.7 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 GAM28256.1 - 5.9e-29 99.8 5.1 1.3e-19 69.9 0.7 3.9 2 1 0 2 2 2 2 Starch binding domain Pneumovirus_M2 PF06436.11 GAM28257.1 - 0.065 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) FmiP_Thoc5 PF09766.9 GAM28257.1 - 0.14 11.4 0.0 0.63 9.3 0.0 1.8 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 zf-MYND PF01753.18 GAM28258.1 - 1.5e-08 34.6 6.8 1.5e-08 34.6 6.8 4.7 3 2 0 3 3 3 1 MYND finger Glyco_hydro_18 PF00704.28 GAM28261.1 - 1.7e-17 64.1 0.6 2.2e-17 63.8 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Dynamin_N PF00350.23 GAM28262.1 - 2.3e-12 47.3 0.0 5.8e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAM28262.1 - 5.7e-05 23.2 0.0 0.00033 20.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 GAM28262.1 - 0.0038 16.3 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Adeno_IVa2 PF02456.15 GAM28262.1 - 0.0041 16.0 0.0 0.0064 15.3 0.0 1.3 1 0 0 1 1 1 1 Adenovirus IVa2 protein Septin PF00735.18 GAM28262.1 - 0.0051 16.1 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Septin AAA_29 PF13555.6 GAM28262.1 - 0.013 15.3 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM28262.1 - 0.013 15.4 0.3 0.082 12.8 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 GAM28262.1 - 0.014 15.9 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 GAM28262.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 GAM28262.1 - 0.14 11.8 0.0 0.79 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAM28264.1 - 0.029 14.4 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 Dynamin family CoA_transf_3 PF02515.17 GAM28264.1 - 0.22 10.6 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 CoA-transferase family III SET PF00856.28 GAM28265.1 - 7.6e-08 32.9 0.0 9.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 SET domain Rad50_zn_hook PF04423.14 GAM28265.1 - 0.46 10.4 3.7 0.42 10.5 0.8 2.1 1 1 1 2 2 2 0 Rad50 zinc hook motif SET PF00856.28 GAM28266.1 - 0.0025 18.2 0.1 0.021 15.2 0.0 2.0 2 0 0 2 2 2 1 SET domain Dynamin_N PF00350.23 GAM28267.1 - 1.4e-11 44.7 0.0 3.6e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAM28267.1 - 1.1e-05 25.4 0.0 2.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Adeno_IVa2 PF02456.15 GAM28267.1 - 0.0049 15.7 0.0 0.01 14.7 0.0 1.5 1 0 0 1 1 1 1 Adenovirus IVa2 protein T2SSE PF00437.20 GAM28267.1 - 0.0088 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 GAM28267.1 - 0.028 14.3 0.2 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 GAM28267.1 - 0.044 13.5 0.1 0.087 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAM28267.1 - 0.07 13.6 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Phage_Integr_2 PF13009.6 GAM28269.1 - 0.13 11.4 0.2 0.22 10.6 0.2 1.3 1 0 0 1 1 1 0 Putative phage integrase Vps5 PF09325.10 GAM28271.1 - 0.028 14.0 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 Vps5 C terminal like SMG1 PF15785.5 GAM28272.1 - 0.011 14.1 0.6 0.018 13.4 0.6 1.3 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 CelTOS PF18659.1 GAM28272.1 - 0.023 15.1 2.7 0.11 12.9 2.0 2.3 1 1 1 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites Pkinase_Tyr PF07714.17 GAM28272.1 - 0.037 13.3 0.9 0.12 11.7 0.2 2.1 2 1 0 2 2 2 0 Protein tyrosine kinase Dynamin_N PF00350.23 GAM28273.1 - 7.8e-13 48.8 0.0 1.6e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAM28273.1 - 9e-06 25.8 0.0 2.1e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 GAM28273.1 - 0.0051 15.9 0.1 0.0084 15.2 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Adeno_IVa2 PF02456.15 GAM28273.1 - 0.0053 15.6 0.0 0.0089 14.9 0.0 1.3 1 0 0 1 1 1 1 Adenovirus IVa2 protein Septin PF00735.18 GAM28273.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 GAM28273.1 - 0.017 14.8 0.2 0.034 13.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAM28273.1 - 0.019 14.9 0.2 0.079 12.9 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 GAM28273.1 - 0.031 14.8 0.0 0.073 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 GAM28273.1 - 0.17 11.2 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family EbsA PF17255.2 GAM28274.1 - 0.058 13.7 1.1 0.092 13.1 1.1 1.3 1 0 0 1 1 1 0 EbsA-like protein Dynamin_N PF00350.23 GAM28275.1 - 7.2e-11 42.4 0.0 2e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAM28275.1 - 0.00032 20.7 0.0 0.0016 18.5 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Adeno_IVa2 PF02456.15 GAM28275.1 - 0.014 14.2 0.1 0.041 12.7 0.1 1.7 1 0 0 1 1 1 0 Adenovirus IVa2 protein ABC_tran PF00005.27 GAM28275.1 - 0.025 15.1 0.0 0.064 13.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 GAM28275.1 - 0.027 13.5 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 GAM28275.1 - 0.029 14.3 1.9 0.065 13.1 0.1 2.5 4 0 0 4 4 4 0 RsgA GTPase AAA_29 PF13555.6 GAM28275.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 GAM28275.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF5554 PF17709.1 GAM28275.1 - 0.13 12.4 0.1 0.67 10.1 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5554) FANCI_S2 PF14676.6 GAM28275.1 - 0.29 11.4 2.7 0.49 10.7 1.1 2.1 2 0 0 2 2 2 0 FANCI solenoid 2 Aldo_ket_red PF00248.21 GAM28276.1 - 1e-46 159.5 0.0 1e-44 153.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HisK_N PF09385.10 GAM28276.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase N terminal AAA_16 PF13191.6 GAM28277.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 GAM28277.1 - 0.024 15.0 0.7 0.11 12.9 0.0 2.6 3 0 0 3 3 3 0 RNA helicase AAA_6 PF12774.7 GAM28277.1 - 0.026 13.5 0.0 0.086 11.8 0.0 1.8 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 GAM28277.1 - 0.044 13.3 1.1 0.17 11.4 0.0 2.5 3 0 0 3 3 3 0 P-loop containing dynein motor region DAP3 PF10236.9 GAM28277.1 - 0.051 12.7 0.1 0.42 9.7 0.0 2.2 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 GAM28277.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Myosin_head PF00063.21 GAM28278.1 - 1.8e-249 829.5 4.0 2.4e-249 829.2 4.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAM28278.1 - 1.1e-38 132.8 2.4 2e-38 132.0 2.4 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 GAM28278.1 - 1.6e-18 66.0 0.2 3.6e-18 64.9 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAM28278.1 - 1.2e-16 60.3 0.1 2.3e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAM28278.1 - 5.5e-12 45.2 0.0 1.2e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 GAM28278.1 - 0.035 14.5 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAM28278.1 - 0.036 14.3 0.0 0.15 12.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAM28278.1 - 0.087 12.1 0.1 0.21 10.8 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 GAM28278.1 - 0.093 13.1 1.8 0.28 11.6 0.0 2.8 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 GAM28278.1 - 0.1 13.1 0.4 0.4 11.2 0.1 2.1 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 GAM28278.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.9 GAM28278.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Phage_Treg PF04761.12 GAM28278.1 - 0.28 11.3 0.8 1.2 9.3 0.2 2.4 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator Myb_DNA-bind_4 PF13837.6 GAM28278.1 - 0.86 10.0 4.2 0.42 11.0 0.7 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Dynamin_N PF00350.23 GAM28279.1 - 0.0045 17.1 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Kinesin PF00225.23 GAM28280.1 - 4.8e-110 367.6 6.7 4.8e-110 367.6 6.7 3.9 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAM28280.1 - 2.7e-25 89.1 0.2 2.7e-25 89.1 0.2 4.7 4 0 0 4 4 4 1 Microtubule binding DUF3450 PF11932.8 GAM28280.1 - 9.7e-05 21.8 9.0 9.7e-05 21.8 9.0 14.8 2 1 13 15 15 15 3 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 GAM28280.1 - 0.00015 21.8 24.5 0.00015 21.8 24.5 14.1 3 2 9 14 14 14 5 TPR/MLP1/MLP2-like protein HIP1_clath_bdg PF16515.5 GAM28280.1 - 0.0031 18.1 15.6 0.0031 18.1 15.6 16.5 4 3 11 17 17 17 3 Clathrin-binding domain of Huntingtin-interacting protein 1 Dynamin_N PF00350.23 GAM28281.1 - 3.5e-11 43.5 0.1 3.7e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family Adeno_IVa2 PF02456.15 GAM28281.1 - 2.4e-05 23.3 0.2 6e-05 22.0 0.1 1.7 1 1 0 1 1 1 1 Adenovirus IVa2 protein MMR_HSR1 PF01926.23 GAM28281.1 - 0.0014 18.7 0.0 0.028 14.5 0.0 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 GAM28281.1 - 0.0015 17.7 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Pkinase PF00069.25 GAM28281.1 - 0.04 13.3 2.0 0.047 13.0 0.0 2.1 3 0 0 3 3 3 0 Protein kinase domain SPATA1_C PF15743.5 GAM28281.1 - 1.2 9.2 5.5 0.3 11.1 1.6 1.9 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus Dynamin_N PF00350.23 GAM28282.1 - 1.2e-07 31.9 0.0 3.3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Pkinase PF00069.25 GAM28282.1 - 3.1e-05 23.5 0.0 8.3e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain MMR_HSR1 PF01926.23 GAM28282.1 - 0.00067 19.7 0.0 0.0041 17.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Pkinase_Tyr PF07714.17 GAM28282.1 - 0.0038 16.6 0.0 0.008 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM28282.1 - 0.013 14.8 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Septin PF00735.18 GAM28282.1 - 0.062 12.6 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 GAM28282.1 - 0.12 12.9 0.0 0.41 11.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 GAM28283.1 - 4.2e-13 49.7 0.0 1.5e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAM28283.1 - 0.00013 22.0 0.0 0.00081 19.5 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM28283.1 - 0.011 15.6 0.1 0.94 9.4 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase DUF848 PF05852.11 GAM28283.1 - 0.21 11.7 0.6 0.61 10.2 0.1 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Dynamin_N PF00350.23 GAM28284.1 - 5e-11 42.9 0.0 4.9e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAM28284.1 - 0.001 19.2 0.0 0.0063 16.6 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 GAM28284.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RE_TdeIII PF09520.10 GAM28284.1 - 0.057 13.1 0.4 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Type II restriction endonuclease, TdeIII ABC_tran PF00005.27 GAM28284.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 GAM28284.1 - 0.15 11.1 0.3 0.35 9.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 GAM28285.1 - 8.8e-11 42.1 0.1 6.9e-10 39.2 0.0 2.5 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAM28285.1 - 0.015 15.4 0.0 0.13 12.4 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 GAM28285.1 - 0.034 13.2 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MitMem_reg PF13012.6 GAM28285.1 - 0.053 13.9 1.0 0.2 12.1 0.1 2.4 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function Pkinase PF00069.25 GAM28286.1 - 9.3e-22 77.6 0.1 1.1e-21 77.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28286.1 - 8.5e-14 51.5 0.1 1.4e-13 50.7 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM28286.1 - 0.00087 18.2 2.6 0.0015 17.4 0.3 2.0 1 1 1 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 GAM28286.1 - 0.03 13.3 0.2 0.038 12.9 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAM28286.1 - 0.069 12.5 0.2 0.093 12.1 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 GAM28286.1 - 0.094 12.0 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Dynamin_N PF00350.23 GAM28287.1 - 1.4e-11 44.8 0.0 3.4e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAM28287.1 - 1.2e-07 31.7 0.0 2e-06 27.8 0.0 2.8 2 2 0 2 2 2 1 50S ribosome-binding GTPase Spore_IV_A PF09547.10 GAM28287.1 - 0.032 13.2 0.2 2.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) AAA_33 PF13671.6 GAM28287.1 - 0.053 13.7 1.6 9.7 6.4 0.1 3.3 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 GAM28287.1 - 0.15 12.6 0.4 0.46 11.0 0.1 2.0 2 0 0 2 2 2 0 ABC transporter SlyX PF04102.12 GAM28287.1 - 0.17 12.6 0.7 0.85 10.3 0.2 2.3 2 0 0 2 2 2 0 SlyX NLE PF08154.12 GAM28287.1 - 0.59 10.7 3.3 1.2 9.7 0.0 3.0 3 0 0 3 3 3 0 NLE (NUC135) domain DASH_Duo1 PF08651.10 GAM28288.1 - 0.67 9.8 3.7 1.6 8.5 0.3 3.0 2 0 0 2 2 2 0 DASH complex subunit Duo1 Dynamin_N PF00350.23 GAM28289.1 - 3.2e-10 40.3 0.0 8.4e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Pkinase PF00069.25 GAM28289.1 - 1.4e-05 24.6 0.4 7.3e-05 22.3 0.1 2.3 2 1 1 3 3 3 1 Protein kinase domain MMR_HSR1 PF01926.23 GAM28289.1 - 0.0015 18.6 0.0 0.037 14.1 0.0 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 GAM28289.1 - 0.0027 16.8 0.0 0.0074 15.4 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein Pkinase_Tyr PF07714.17 GAM28289.1 - 0.0085 15.4 0.1 0.051 12.9 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase RsgA_GTPase PF03193.16 GAM28289.1 - 0.044 13.7 0.2 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase BioW PF03744.13 GAM28289.1 - 0.33 10.5 1.5 0.57 9.7 0.5 1.9 2 0 0 2 2 2 0 6-carboxyhexanoate--CoA ligase Dynamin_N PF00350.23 GAM28290.1 - 1e-10 41.9 0.0 3.3e-10 40.3 0.0 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAM28290.1 - 0.0014 18.7 0.0 0.02 15.0 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Vps5 PF09325.10 GAM28290.1 - 0.025 14.1 0.4 0.025 14.1 0.4 2.3 3 0 0 3 3 3 0 Vps5 C terminal like RsgA_GTPase PF03193.16 GAM28290.1 - 0.066 13.1 0.9 0.21 11.5 0.3 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 GAM28290.1 - 0.081 12.7 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAM28290.1 - 0.087 13.3 0.1 0.32 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter T2SSE PF00437.20 GAM28290.1 - 0.13 11.3 1.0 0.48 9.4 0.2 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein FTA4 PF13093.6 GAM28290.1 - 0.19 11.6 3.3 2.8 7.8 0.4 2.7 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Dynamin_N PF00350.23 GAM28291.1 - 7e-08 32.7 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAM28291.1 - 0.0013 18.8 0.0 0.019 15.1 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAM28291.1 - 0.0054 17.2 0.0 0.016 15.7 0.0 1.8 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 GAM28291.1 - 0.026 14.4 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 GAM28291.1 - 0.082 12.9 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Chloroplast_duf PF14476.6 GAM28291.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Petal formation-expressed cobW PF02492.19 GAM28291.1 - 0.13 11.8 1.2 0.33 10.5 1.2 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 GAM28291.1 - 0.16 12.2 0.1 0.99 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 GAM28292.1 - 6.5e-32 110.9 0.0 1.5e-31 109.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28292.1 - 4.9e-24 85.0 0.0 7.5e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Dynamin_N PF00350.23 GAM28292.1 - 1e-13 51.7 0.0 2.9e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAM28292.1 - 4.2e-06 26.8 0.0 1.2e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Kdo PF06293.14 GAM28292.1 - 0.018 14.4 0.1 0.039 13.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 GAM28292.1 - 0.052 14.1 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter FLgD_tudor PF13861.6 GAM28292.1 - 0.18 12.1 0.0 1.2 9.5 0.0 2.3 3 0 0 3 3 3 0 FlgD Tudor-like domain AAA_28 PF13521.6 GAM28292.1 - 0.18 12.0 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_C48 PF02902.19 GAM28295.1 - 0.00013 21.9 0.2 0.00023 21.1 0.2 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Dicty_REP PF05086.12 GAM28295.1 - 0.0035 15.4 5.0 0.0038 15.3 5.0 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.11 GAM28295.1 - 0.01 14.0 5.3 0.013 13.7 5.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ecl1 PF12855.7 GAM28295.1 - 0.03 15.5 12.4 0.042 15.0 12.4 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins SSP160 PF06933.11 GAM28295.1 - 0.049 11.8 15.8 0.059 11.6 15.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HNF-1_N PF04814.13 GAM28295.1 - 0.24 12.0 7.4 0.31 11.6 6.0 1.8 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus EBP50_C PF09007.11 GAM28295.1 - 0.29 12.1 5.5 0.48 11.4 5.5 1.4 1 0 0 1 1 1 0 EBP50, C-terminal SWI-SNF_Ssr4 PF08549.10 GAM28295.1 - 0.4 9.3 6.1 0.49 9.0 6.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) MGC-24 PF05283.11 GAM28295.1 - 1.1 9.7 13.1 1.9 8.9 13.1 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Macoilin PF09726.9 GAM28295.1 - 1.8 7.0 7.6 2 6.9 7.6 1.1 1 0 0 1 1 1 0 Macoilin family adh_short PF00106.25 GAM28297.1 - 1.1e-46 158.7 0.2 1.4e-46 158.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM28297.1 - 3.9e-33 115.0 0.0 5.3e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM28297.1 - 5.1e-06 26.5 0.1 8.9e-06 25.7 0.1 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAM28297.1 - 8.6e-06 25.3 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 GAM28297.1 - 0.049 13.1 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F-box PF00646.33 GAM28298.1 - 7.9e-05 22.4 0.2 0.00019 21.2 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM28298.1 - 0.00011 22.1 0.6 0.00042 20.2 0.2 2.0 2 0 0 2 2 2 1 F-box-like DUF3328 PF11807.8 GAM28298.1 - 0.013 15.2 2.4 0.017 14.9 2.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) Zip PF02535.22 GAM28298.1 - 0.22 10.7 0.5 0.29 10.3 0.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pkinase PF00069.25 GAM28300.1 - 7.3e-78 261.6 0.3 8.9e-78 261.3 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28300.1 - 2.5e-35 122.0 0.2 3.1e-35 121.7 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM28300.1 - 5.7e-08 32.4 0.0 1.7e-06 27.6 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAM28300.1 - 3e-05 23.5 0.1 4.7e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM28300.1 - 0.00011 21.1 0.5 0.00038 19.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAM28300.1 - 0.00063 19.7 0.0 0.097 12.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 GAM28300.1 - 0.012 15.3 0.7 0.021 14.4 0.7 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 GAM28300.1 - 0.016 14.2 0.6 0.023 13.6 0.6 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 GAM28300.1 - 0.027 14.1 0.7 0.15 11.7 0.7 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Solute_trans_a PF03619.16 GAM28301.1 - 1.9e-97 325.9 24.3 2.6e-97 325.5 24.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PIP5K PF01504.18 GAM28302.1 - 1.4e-75 254.0 1.1 2.6e-75 253.2 1.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ank_4 PF13637.6 GAM28302.1 - 9.9e-29 99.3 0.1 2e-11 44.2 0.0 4.7 4 1 1 5 5 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM28302.1 - 4.7e-24 84.8 0.0 3.3e-11 43.6 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAM28302.1 - 4.6e-20 71.1 0.2 0.0001 22.6 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAM28302.1 - 1.4e-19 69.9 0.0 1.8e-08 34.5 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28302.1 - 8.3e-18 62.6 0.0 0.00042 20.5 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat EF-hand_7 PF13499.6 GAM28302.1 - 4.8e-16 59.0 1.5 1.3e-07 32.0 0.4 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 GAM28302.1 - 1.8e-13 49.2 1.0 0.00051 19.8 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 GAM28302.1 - 4e-12 44.8 0.4 0.0018 17.7 0.2 3.7 3 0 0 3 3 3 3 EF hand C1_1 PF00130.22 GAM28302.1 - 1.2e-11 44.3 6.9 2.4e-11 43.4 6.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) NADPH_Ox PF08414.10 GAM28302.1 - 8.8e-07 29.2 0.2 2.8e-06 27.6 0.2 1.9 1 1 0 1 1 1 1 Respiratory burst NADPH oxidase EF-hand_8 PF13833.6 GAM28302.1 - 0.00034 20.4 0.3 0.15 11.9 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAM28302.1 - 0.0035 17.7 2.9 0.085 13.2 0.7 3.0 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 GAM28302.1 - 0.008 15.6 2.2 0.091 12.3 0.2 3.1 3 0 0 3 3 3 1 EF hand GST_N_3 PF13417.6 GAM28302.1 - 0.016 15.6 0.1 0.77 10.2 0.0 3.5 4 0 0 4 4 4 0 Glutathione S-transferase, N-terminal domain C1_2 PF03107.16 GAM28302.1 - 0.053 13.8 4.5 0.13 12.6 4.5 1.7 1 0 0 1 1 1 0 C1 domain EF-hand_9 PF14658.6 GAM28302.1 - 0.14 12.5 0.1 12 6.4 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Pur_DNA_glyco PF02245.16 GAM28303.1 - 0.0025 17.3 0.0 0.0028 17.1 0.0 1.1 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) Amj PF10997.8 GAM28303.1 - 0.097 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Alternate to MurJ Vault PF01505.18 GAM28304.1 - 1.5e-56 188.3 0.7 4e-15 55.7 0.0 5.0 4 0 0 4 4 4 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 GAM28304.1 - 4.7e-47 158.9 0.0 8.9e-47 158.0 0.0 1.5 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 GAM28304.1 - 1.8e-34 117.9 0.0 1.5e-21 76.5 0.1 2.7 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 GAM28304.1 - 4.4e-34 116.3 0.5 3.7e-29 100.6 0.0 3.6 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 GAM28304.1 - 4.9e-22 77.8 0.0 3.3e-21 75.1 0.0 2.3 2 0 0 2 2 2 1 Major Vault Protein repeat domain Urb2 PF10441.9 GAM28305.1 - 1.2e-12 48.3 2.1 1.2e-12 48.3 2.1 5.1 4 1 0 5 5 5 1 Urb2/Npa2 family FNIP PF05725.12 GAM28306.1 - 1.3e-45 153.3 11.7 8.5e-13 48.2 0.1 7.9 7 2 3 10 10 10 6 FNIP Repeat FNIP PF05725.12 GAM28307.1 - 6.1e-65 215.2 0.0 1.3e-12 47.7 0.2 9.2 6 2 1 9 9 9 8 FNIP Repeat TFIIA PF03153.13 GAM28307.1 - 0.86 9.5 9.2 1 9.3 9.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP PF05725.12 GAM28308.1 - 1.1e-47 159.9 22.2 4.5e-14 52.3 0.6 7.0 5 1 2 7 7 7 6 FNIP Repeat FNIP PF05725.12 GAM28310.1 - 3e-51 171.3 27.0 1.2e-16 60.6 0.4 5.8 4 1 3 7 7 7 5 FNIP Repeat Ribosomal_L18A PF01775.17 GAM28311.1 - 2.7e-49 166.3 3.0 3.5e-49 165.9 3.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A His_Phos_2 PF00328.22 GAM28312.1 - 7e-22 78.3 0.0 8.5e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RhoGEF PF00621.20 GAM28313.1 - 6.1e-45 153.7 0.2 2.7e-44 151.6 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain Ion_trans PF00520.31 GAM28313.1 - 0.00022 20.6 7.7 0.00022 20.6 7.7 1.9 3 0 0 3 3 3 1 Ion transport protein PH PF00169.29 GAM28313.1 - 0.0018 18.8 0.1 0.0088 16.5 0.0 2.2 1 1 1 2 2 2 1 PH domain PH_9 PF15410.6 GAM28313.1 - 0.11 12.9 0.4 0.71 10.2 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain LMSTEN PF07988.12 GAM28314.1 - 0.071 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 LMSTEN motif PH PF00169.29 GAM28315.1 - 5.8e-19 68.6 0.6 1.1e-18 67.7 0.6 1.5 1 0 0 1 1 1 1 PH domain TPR_12 PF13424.6 GAM28315.1 - 8.2e-07 29.2 8.2 0.0024 18.1 0.2 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat PH_11 PF15413.6 GAM28315.1 - 0.00013 22.3 3.7 0.0011 19.4 3.7 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAM28315.1 - 0.03 14.6 0.3 0.11 12.7 0.3 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain PH_13 PF16652.5 GAM28315.1 - 0.044 13.6 0.4 0.13 12.1 0.4 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 GAM28315.1 - 0.075 13.4 5.1 0.19 12.1 1.2 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain L_lactis_RepB_C PF06430.12 GAM28315.1 - 0.076 13.0 1.8 0.22 11.5 1.8 1.8 1 0 0 1 1 1 0 Lactococcus lactis RepB C-terminus TPR_2 PF07719.17 GAM28315.1 - 0.43 10.8 3.2 2.2 8.6 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAM28315.1 - 0.47 10.8 7.2 26 5.4 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 GAM28316.1 - 4.5e-36 124.3 0.0 5.4e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Gtr1_RagA PF04670.12 GAM28318.1 - 4.3e-104 346.9 2.7 5.7e-104 346.5 2.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 GAM28318.1 - 4.7e-10 39.7 0.5 2.1e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAM28318.1 - 1.2e-09 38.0 0.0 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.21 GAM28318.1 - 3.7e-09 36.3 0.1 6.2e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM28318.1 - 1.4e-07 31.6 0.0 3.3e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAM28318.1 - 0.00098 18.6 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 GAM28318.1 - 0.064 13.0 0.1 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SCAPER_N PF16501.5 GAM28318.1 - 0.18 11.8 1.7 0.33 11.0 0.1 2.2 3 0 0 3 3 3 0 S phase cyclin A-associated protein in the endoplasmic reticulum G-alpha PF00503.20 GAM28318.1 - 0.29 10.3 10.8 1.4 8.0 0.1 3.2 1 1 2 3 3 3 0 G-protein alpha subunit TMPIT PF07851.13 GAM28319.1 - 1.1e-102 343.6 6.9 1.3e-102 343.4 6.9 1.0 1 0 0 1 1 1 1 TMPIT-like protein DUF2730 PF10805.8 GAM28319.1 - 0.14 12.2 0.8 0.46 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) CENP-H PF05837.12 GAM28319.1 - 1.3 9.4 5.8 4.8 7.6 1.1 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Lyase_aromatic PF00221.19 GAM28320.1 - 8.1e-191 634.7 0.7 9.2e-191 634.5 0.7 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase FNIP PF05725.12 GAM28321.1 - 1.7e-32 111.3 3.4 3e-12 46.5 0.1 3.6 1 1 1 3 3 3 3 FNIP Repeat FNIP PF05725.12 GAM28322.1 - 5.9e-62 205.6 9.9 8.2e-14 51.5 0.1 8.1 5 2 4 9 9 9 7 FNIP Repeat Crystallin PF00525.18 GAM28322.1 - 0.0018 18.4 1.1 0.15 12.3 0.2 2.8 1 1 1 2 2 2 2 Alpha crystallin A chain, N terminal LRR_1 PF00560.33 GAM28322.1 - 0.11 13.1 2.1 68 4.6 0.1 4.5 5 1 0 5 5 5 0 Leucine Rich Repeat FNIP PF05725.12 GAM28323.1 - 2.5e-66 219.6 40.4 5.5e-12 45.7 0.0 9.3 3 3 8 12 12 12 11 FNIP Repeat FNIP PF05725.12 GAM28324.1 - 1.6e-63 210.7 40.7 9.5e-15 54.5 0.7 10.2 6 3 2 10 10 10 8 FNIP Repeat LRR_1 PF00560.33 GAM28324.1 - 0.32 11.7 12.2 61 4.8 0.2 6.6 5 1 1 6 6 6 0 Leucine Rich Repeat FNIP PF05725.12 GAM28325.1 - 1.5e-72 239.5 45.9 4.2e-14 52.4 0.3 7.9 2 1 8 10 10 10 10 FNIP Repeat FNIP PF05725.12 GAM28326.1 - 1.6e-61 204.3 28.3 3.6e-13 49.5 0.5 8.5 4 2 5 9 9 9 8 FNIP Repeat Atg14 PF10186.9 GAM28327.1 - 2e-15 56.7 8.3 2e-15 56.7 8.3 2.2 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 GAM28327.1 - 5.9e-06 25.4 16.3 5.9e-06 25.4 16.3 3.7 3 1 0 3 3 3 2 Vacuolar protein sorting 38 APG6 PF04111.12 GAM28327.1 - 5.4e-05 23.2 0.0 0.00021 21.3 0.0 2.0 1 1 0 1 1 1 1 Apg6 BARA domain C2 PF00168.30 GAM28327.1 - 0.028 14.7 0.1 0.12 12.7 0.1 2.1 1 0 0 1 1 1 0 C2 domain Caldesmon PF02029.15 GAM28327.1 - 5.8 5.5 20.4 0.059 12.1 7.4 2.1 2 0 0 2 2 2 0 Caldesmon Cyclin_N PF00134.23 GAM28328.1 - 0.00059 19.6 0.1 0.00092 19.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAM28328.1 - 0.0026 18.1 0.1 0.0026 18.1 0.1 2.2 2 0 0 2 2 2 1 Cyclin Erf4 PF10256.9 GAM28328.1 - 0.16 12.1 3.6 1.6 8.9 0.8 3.2 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family WD40 PF00400.32 GAM28329.1 - 1.1e-16 60.9 10.9 0.00053 20.7 0.0 8.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM28329.1 - 5.7e-10 39.4 1.3 0.0009 19.5 0.5 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Zn_ribbon_17 PF17120.5 GAM28329.1 - 5.1e-07 29.2 10.7 5.1e-07 29.2 10.7 2.2 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type BBS2_Mid PF14783.6 GAM28329.1 - 0.00045 20.2 0.0 0.0075 16.3 0.0 3.1 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region zinc_ribbon_16 PF17034.5 GAM28329.1 - 0.00092 19.4 6.1 0.00092 19.4 6.1 2.7 1 1 1 2 2 2 1 Zinc-ribbon like family DZR PF12773.7 GAM28329.1 - 0.37 10.9 10.3 1 9.5 10.3 1.8 1 0 0 1 1 1 0 Double zinc ribbon DUF3430 PF11912.8 GAM28330.1 - 1.7e-20 74.0 14.2 2e-20 73.8 14.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3430 PF11912.8 GAM28331.1 - 5e-18 65.9 30.4 5e-18 65.9 30.4 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3430) FNIP PF05725.12 GAM28332.1 - 3.4e-51 171.1 36.6 8.2e-13 48.3 2.9 8.5 6 2 1 8 8 8 7 FNIP Repeat FNIP PF05725.12 GAM28333.1 - 1.1e-75 249.6 39.2 2e-13 50.2 0.6 9.5 9 1 1 10 10 10 9 FNIP Repeat Rtt106_N PF18215.1 GAM28333.1 - 0.046 13.5 0.3 2.7 7.8 0.0 3.7 4 0 0 4 4 4 0 Histone chaperone Rtt106 N-terminal domain DUF5493 PF17597.2 GAM28333.1 - 0.15 12.3 10.6 0.56 10.5 0.1 4.6 4 2 2 6 6 6 0 Family of unknown function (DUF5493) Ribosomal_L24e PF01246.20 GAM28334.1 - 1.3e-32 111.8 4.5 1.3e-32 111.8 4.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e CpXC PF14353.6 GAM28334.1 - 0.088 12.9 1.8 3.7 7.6 0.0 2.1 1 1 1 2 2 2 0 CpXC protein UCH PF00443.29 GAM28335.1 - 6.3e-49 166.8 0.1 6.3e-49 166.8 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM28335.1 - 3.2e-20 73.0 1.4 3.2e-20 73.0 1.4 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Exonuc_VII_L PF02601.15 GAM28335.1 - 2.2 7.8 20.3 0.15 11.6 11.4 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Pkinase_Tyr PF07714.17 GAM28336.1 - 7.2e-60 202.4 0.0 9.3e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM28336.1 - 2.7e-48 164.6 0.0 3.7e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 GAM28336.1 - 7.2e-16 58.1 0.1 1.3e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 GAM28336.1 - 0.00036 20.5 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM28336.1 - 0.00043 19.3 0.0 0.0042 16.1 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain ABC1 PF03109.16 GAM28336.1 - 0.017 15.3 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 ABC1 family EF-hand_12 PF17901.1 GAM28336.1 - 0.072 13.6 0.1 0.47 11.0 0.0 2.2 2 0 0 2 2 2 0 EF-hand fold domain WD40 PF00400.32 GAM28338.1 - 2.1e-16 60.0 12.0 0.00011 22.9 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Peptidase_S29 PF02907.15 GAM28338.1 - 0.00056 19.7 0.1 0.0018 18.0 0.1 1.8 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease SIR2 PF02146.17 GAM28339.1 - 2.5e-27 95.9 0.0 4.3e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TusA PF01206.17 GAM28339.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Sulfurtransferase TusA SIR2 PF02146.17 GAM28340.1 - 3e-16 59.9 0.0 3.6e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 GAM28340.1 - 0.0039 16.9 0.0 0.0039 16.9 0.0 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain HdeA PF06411.11 GAM28342.1 - 0.042 14.0 0.2 0.049 13.8 0.2 1.1 1 0 0 1 1 1 0 HdeA/HdeB family PyrI_C PF02748.15 GAM28342.1 - 0.072 13.0 0.4 0.1 12.5 0.4 1.2 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF761 PF05553.11 GAM28342.1 - 2.9 7.5 0.1 2.9 7.5 0.1 2.8 3 1 0 3 3 3 0 Cotton fibre expressed protein ARS2 PF04959.13 GAM28343.1 - 0.0097 16.3 1.3 0.012 16.0 1.3 1.1 1 0 0 1 1 1 1 Arsenite-resistance protein 2 rRNA_proc-arch PF13234.6 GAM28343.1 - 0.032 14.2 0.1 0.038 13.9 0.1 1.0 1 0 0 1 1 1 0 rRNA-processing arch domain UPF0154 PF03672.13 GAM28343.1 - 0.15 12.1 0.6 0.24 11.5 0.6 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0154) Myosin_head PF00063.21 GAM28344.1 - 3.8e-245 815.3 13.0 6.7e-244 811.1 13.0 2.4 1 1 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 GAM28344.1 - 4.7e-45 152.5 7.2 1.3e-23 83.5 0.4 3.6 3 0 0 3 3 3 2 MyTH4 domain SH3_2 PF07653.17 GAM28344.1 - 1e-10 41.1 0.0 1.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAM28344.1 - 1.9e-10 40.4 0.0 4.4e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain FERM_M PF00373.18 GAM28344.1 - 9.9e-10 38.9 0.1 8.8e-07 29.3 0.2 3.5 2 0 0 2 2 2 1 FERM central domain SH3_1 PF00018.28 GAM28344.1 - 7.5e-09 35.1 0.0 1.9e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain RA PF00788.23 GAM28344.1 - 2.6e-07 31.2 0.1 9.3e-06 26.2 0.0 3.3 4 0 0 4 4 2 1 Ras association (RalGDS/AF-6) domain IQ PF00612.27 GAM28344.1 - 7.8e-07 28.3 25.8 0.0011 18.6 0.5 5.0 5 0 0 5 5 4 3 IQ calmodulin-binding motif BUD22 PF09073.10 GAM28344.1 - 0.00045 19.7 12.2 0.001 18.5 12.2 1.5 1 0 0 1 1 1 1 BUD22 FERM_C PF09380.10 GAM28344.1 - 0.02 15.2 0.0 0.02 15.2 0.0 3.1 3 0 0 3 3 3 0 FERM C-terminal PH-like domain AAA_16 PF13191.6 GAM28344.1 - 0.034 14.5 4.9 0.057 13.8 0.0 3.3 3 0 0 3 3 2 0 AAA ATPase domain FERM_N PF09379.10 GAM28344.1 - 0.04 13.9 0.0 1 9.4 0.0 2.7 2 0 0 2 2 2 0 FERM N-terminal domain AAA_22 PF13401.6 GAM28344.1 - 0.087 13.1 1.1 0.27 11.5 0.0 2.6 2 0 0 2 2 1 0 AAA domain Asp-B-Hydro_N PF05279.11 GAM28344.1 - 3.2 7.8 17.1 7.7 6.5 17.1 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Scramblase PF03803.15 GAM28345.1 - 0.00014 21.3 0.0 0.00049 19.5 0.0 1.8 1 1 0 1 1 1 1 Scramblase CAP_C PF08603.11 GAM28345.1 - 0.014 15.0 0.9 1.8 8.2 0.0 3.6 2 2 2 4 4 4 0 Adenylate cyclase associated (CAP) C terminal Peptidase_C24 PF03510.14 GAM28345.1 - 5 7.6 7.2 4.1 7.9 1.4 2.6 1 1 1 2 2 2 0 2C endopeptidase (C24) cysteine protease family Intg_mem_TP0381 PF09529.10 GAM28347.1 - 0.099 12.1 12.7 0.23 10.9 0.4 2.8 3 0 0 3 3 3 0 Integral membrane protein (intg_mem_TP0381) PAP2 PF01569.21 GAM28347.1 - 0.17 11.6 5.0 1.1 9.1 0.9 2.4 2 0 0 2 2 2 0 PAP2 superfamily CopD PF05425.13 GAM28347.1 - 0.19 12.1 4.4 0.5 10.8 0.1 2.3 2 0 0 2 2 2 0 Copper resistance protein D Polysacc_synt_C PF14667.6 GAM28347.1 - 1.2 9.2 11.4 2.3 8.3 1.3 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain FtsK_4TM PF13491.6 GAM28347.1 - 7.6 6.2 8.8 3.4 7.3 0.5 2.4 3 0 0 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE Usp PF00582.26 GAM28348.1 - 5.4e-19 69.1 0.0 5.4e-19 69.1 0.0 1.5 2 0 0 2 2 2 1 Universal stress protein family Aminotran_1_2 PF00155.21 GAM28349.1 - 7.2e-61 206.4 0.0 8.8e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAM28349.1 - 4.5e-06 26.2 0.0 6.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.21 GAM28349.1 - 0.0064 15.2 0.0 0.0096 14.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Alliinase_C PF04864.13 GAM28349.1 - 0.011 14.7 0.1 0.061 12.2 0.1 2.0 1 1 0 1 1 1 0 Allinase SepSecS PF05889.13 GAM28349.1 - 0.17 10.5 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Kelch_1 PF01344.25 GAM28350.1 - 7.4e-17 60.7 10.4 6.8e-05 22.4 0.4 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 GAM28350.1 - 7.3e-14 51.5 10.8 1.2e-06 28.6 0.2 5.4 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.6 GAM28350.1 - 4.3e-09 36.2 10.7 0.00029 20.8 0.1 5.8 4 2 2 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM28350.1 - 2.7e-08 33.9 2.5 0.048 14.0 0.0 5.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM28350.1 - 2.4e-06 27.4 5.2 0.069 13.2 0.1 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 GAM28350.1 - 5.6e-05 23.0 6.6 0.067 13.2 0.2 4.2 3 0 0 3 3 3 2 Kelch motif Snf7 PF03357.21 GAM28351.1 - 3.2e-17 62.7 8.2 3.2e-17 62.7 8.2 2.5 2 0 0 2 2 2 1 Snf7 RLL PF10036.9 GAM28351.1 - 0.0041 17.0 6.7 0.0066 16.3 6.7 1.3 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein DUF3439 PF11921.8 GAM28351.1 - 0.017 15.0 8.3 0.017 15.0 8.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF932 PF06067.11 GAM28351.1 - 0.034 13.9 3.5 0.066 13.0 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Phage_lysozyme PF00959.19 GAM28351.1 - 0.087 13.3 0.2 1.2 9.7 0.1 2.4 2 0 0 2 2 2 0 Phage lysozyme Rep_fac_C PF08542.11 GAM28351.1 - 0.16 12.4 1.6 0.63 10.5 1.2 2.3 1 1 1 2 2 2 0 Replication factor C C-terminal domain Anillin_N PF16018.5 GAM28351.1 - 0.16 12.6 2.9 1.1 9.9 1.6 2.7 2 0 0 2 2 2 0 Anillin N-terminus DUF2407_C PF13373.6 GAM28351.1 - 0.31 11.2 2.1 0.65 10.2 2.1 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain Mucin PF01456.17 GAM28351.1 - 2.6 8.1 23.3 0.27 11.2 18.0 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein 40S_SA_C PF16122.5 GAM28351.1 - 3.5 9.1 10.0 7.8 7.9 8.8 2.1 2 0 0 2 2 2 0 40S ribosomal protein SA C-terminus Kinesin_assoc PF16183.5 GAM28351.1 - 3.7 7.7 9.6 0.57 10.3 3.5 2.5 2 1 1 3 3 3 0 Kinesin-associated OprD PF03573.13 GAM28352.1 - 0.22 10.5 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 outer membrane porin, OprD family FA_hydroxylase PF04116.13 GAM28354.1 - 2.3e-27 96.0 14.3 2.3e-27 96.0 14.3 2.8 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily Pkinase PF00069.25 GAM28355.1 - 8.8e-65 218.7 0.0 1.1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28355.1 - 2.3e-19 69.7 0.0 3.4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM28355.1 - 1.5e-06 28.3 0.0 2e-05 24.6 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAM28355.1 - 0.0034 16.2 0.1 0.014 14.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 GAM28355.1 - 0.018 14.7 0.1 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 GAM28355.1 - 0.079 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FhuF PF06276.12 GAM28355.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Ycf66_N PF07444.11 GAM28356.1 - 0.024 14.7 0.1 0.026 14.6 0.1 1.1 1 0 0 1 1 1 0 Ycf66 protein N-terminus Ras PF00071.22 GAM28357.1 - 1e-58 197.5 0.1 1.2e-58 197.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM28357.1 - 4.7e-34 117.2 0.1 6.4e-34 116.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM28357.1 - 8.1e-18 64.5 0.0 9.9e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM28357.1 - 2.2e-09 37.4 0.0 3.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAM28357.1 - 6.6e-06 25.8 0.0 0.00023 20.7 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAM28357.1 - 0.00024 20.6 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAM28357.1 - 0.0032 16.8 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 GAM28357.1 - 0.0049 16.4 0.1 0.014 14.9 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 GAM28357.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TniB PF05621.11 GAM28357.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Lipase_3 PF01764.25 GAM28358.1 - 2.1e-13 50.3 0.0 5e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GAM28358.1 - 0.011 16.3 0.0 0.048 14.3 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family AAA_31 PF13614.6 GAM28358.1 - 0.11 12.4 0.1 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2974 PF11187.8 GAM28358.1 - 0.2 11.2 0.3 0.91 9.0 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) LSM PF01423.22 GAM28359.1 - 2.3e-20 72.0 0.7 2.8e-20 71.8 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAM28359.1 - 2.6e-06 27.5 0.0 3.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 GAM28359.1 - 0.068 13.3 0.0 0.092 12.9 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain LSM14 PF12701.7 GAM28359.1 - 0.096 12.8 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain TFIIA PF03153.13 GAM28360.1 - 0.019 15.0 40.5 0.022 14.8 40.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PepSY_TM PF03929.16 GAM28360.1 - 0.03 14.0 2.6 0.037 13.7 2.6 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DDHD PF02862.17 GAM28360.1 - 0.032 14.4 4.7 0.039 14.1 4.7 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 GAM28360.1 - 0.035 12.9 9.2 0.039 12.7 9.2 1.2 1 0 0 1 1 1 0 Presenilin CTD_bind PF04818.13 GAM28360.1 - 0.082 13.8 0.2 0.082 13.8 0.2 2.1 2 1 0 2 2 1 0 RNA polymerase II-binding domain. DUF4407 PF14362.6 GAM28360.1 - 0.092 12.1 18.0 0.13 11.6 18.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.9 GAM28360.1 - 0.12 10.6 26.2 0.14 10.4 26.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 VIT1 PF01988.19 GAM28360.1 - 0.28 11.0 5.4 0.47 10.3 5.4 1.4 1 0 0 1 1 1 0 VIT family LAP1C PF05609.12 GAM28360.1 - 0.31 10.1 13.2 0.36 9.9 13.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ALMT PF11744.8 GAM28360.1 - 0.32 9.8 6.2 0.41 9.4 6.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter EIF4E-T PF10477.9 GAM28360.1 - 1 8.1 21.3 1.4 7.7 21.3 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Neur_chan_memb PF02932.16 GAM28360.1 - 1.2 9.1 9.2 1.7 8.7 9.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 GAM28360.1 - 1.6 8.7 7.8 2.5 8.1 7.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Med15 PF09606.10 GAM28360.1 - 6.3 5.4 54.8 7.4 5.1 54.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Kelch_4 PF13418.6 GAM28361.1 - 1.2e-09 38.1 0.5 0.00011 22.1 0.1 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAM28361.1 - 1.6e-06 27.6 0.8 0.017 14.7 0.1 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 GAM28361.1 - 4.7e-05 23.5 2.8 0.017 15.4 0.1 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 GAM28361.1 - 0.061 13.3 5.6 3.4 7.8 0.0 3.3 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.6 GAM28361.1 - 1.9 8.6 7.0 14 5.8 0.4 2.9 3 0 0 3 3 3 0 Kelch motif TniB PF05621.11 GAM28362.1 - 0.0077 15.7 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein ATPase_2 PF01637.18 GAM28362.1 - 0.034 14.0 0.1 0.12 12.2 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Vinculin PF01044.19 GAM28363.1 - 8.3e-13 47.5 133.1 1.1e-08 33.8 31.7 6.7 2 1 4 6 6 6 3 Vinculin family LANC_like PF05147.13 GAM28363.1 - 0.0068 15.0 6.8 1.1 7.8 0.2 3.3 2 1 0 2 2 2 2 Lanthionine synthetase C-like protein DUF5071 PF16804.5 GAM28363.1 - 0.052 13.8 7.5 0.3 11.3 0.0 5.5 6 1 0 6 6 6 0 Domain of unknown function (DUF5071) Ank_2 PF12796.7 GAM28364.1 - 1.5e-08 35.1 0.1 6.9e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28364.1 - 7.8e-06 26.3 0.0 0.00011 22.7 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 GAM28364.1 - 1.5e-05 25.2 0.3 0.65 10.6 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAM28364.1 - 4.1e-05 23.8 0.1 0.00027 21.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28364.1 - 0.0045 17.4 1.0 0.24 12.1 0.0 4.2 5 1 0 5 5 5 1 Ankyrin repeat F-box-like PF12937.7 GAM28364.1 - 0.0079 16.1 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like CBS PF00571.28 GAM28365.1 - 4.1e-17 62.4 0.0 9.6e-05 22.8 0.0 4.4 4 0 0 4 4 4 3 CBS domain PB1 PF00564.24 GAM28365.1 - 0.1 12.5 0.0 0.74 9.8 0.0 2.1 2 0 0 2 2 2 0 PB1 domain WD40 PF00400.32 GAM28366.1 - 1.4e-14 54.2 26.3 0.013 16.3 0.2 11.1 11 0 0 11 11 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM28366.1 - 2.7e-09 37.2 1.1 1.6 9.1 0.0 7.4 7 2 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAM28366.1 - 0.023 14.0 0.0 2 7.7 0.0 3.3 4 0 0 4 4 4 0 WD40-like domain HEAT_EZ PF13513.6 GAM28366.1 - 0.053 14.1 0.0 7.9 7.1 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat Coatomer_WDAD PF04053.14 GAM28366.1 - 0.077 12.0 0.0 8.1 5.4 0.0 2.7 3 0 0 3 3 3 0 Coatomer WD associated region Copine PF07002.16 GAM28367.1 - 2.8e-68 229.6 0.0 3.4e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 GAM28367.1 - 1.1e-10 41.9 0.0 1.7e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 GAM28367.1 - 0.00019 21.7 0.0 0.0013 19.0 0.0 2.1 2 1 1 3 3 3 1 von Willebrand factor type A domain Fez1 PF06818.15 GAM28368.1 - 1.8e-05 25.3 64.0 3.9e-05 24.2 27.7 14.4 1 1 12 13 13 13 4 Fez1 Rootletin PF15035.6 GAM28368.1 - 0.00058 19.9 22.4 0.00058 19.9 22.4 16.2 1 1 11 13 13 13 1 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.11 GAM28368.1 - 0.00091 19.5 60.9 0.0027 18.0 26.5 17.3 1 1 13 15 15 15 4 Autophagy protein 16 (ATG16) Atg14 PF10186.9 GAM28368.1 - 0.0027 16.8 9.1 0.0027 16.8 9.1 14.9 1 1 12 13 13 13 2 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_TL5_C PF14693.6 GAM28368.1 - 0.0027 18.0 0.1 1.9 8.9 0.0 3.3 2 0 0 2 2 2 1 Ribosomal protein TL5, C-terminal domain Sec2p PF06428.11 GAM28368.1 - 0.0057 16.6 8.8 0.0057 16.6 8.8 23.4 5 3 18 26 26 26 3 GDP/GTP exchange factor Sec2p DUF211 PF02680.14 GAM28368.1 - 0.21 11.8 7.2 3.4 7.9 0.1 5.7 3 2 1 4 4 4 0 Uncharacterized ArCR, COG1888 Filament PF00038.21 GAM28368.1 - 2.7 7.5 326.2 0.04 13.5 19.4 12.8 1 1 10 12 12 12 0 Intermediate filament protein WD40_alt PF14077.6 GAM28368.1 - 3.5 7.6 7.5 3.8 7.5 0.2 5.4 5 0 0 5 5 5 0 Alternative WD40 repeat motif Pkinase PF00069.25 GAM28369.1 - 1.9e-67 227.4 0.0 1.9e-67 227.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28369.1 - 4.1e-31 108.2 0.0 4.1e-31 108.2 0.0 2.8 3 1 0 3 3 3 1 Protein tyrosine kinase TFIIA PF03153.13 GAM28369.1 - 0.017 15.1 45.4 0.025 14.6 45.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rit1_C PF17184.4 GAM28369.1 - 1.3 8.5 13.2 2.1 7.7 13.2 1.2 1 0 0 1 1 1 0 Rit1 N-terminal domain Presenilin PF01080.17 GAM28369.1 - 2.4 6.8 21.0 3.4 6.3 21.0 1.1 1 0 0 1 1 1 0 Presenilin CDK5_activator PF03261.15 GAM28369.1 - 3.7 7.0 26.3 6 6.3 26.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Ndc1_Nup PF09531.10 GAM28369.1 - 3.8 6.1 13.9 5 5.7 13.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 GAM28369.1 - 5.3 5.2 39.6 6.9 4.8 39.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4045 PF13254.6 GAM28369.1 - 8.8 5.9 16.0 16 5.0 16.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Myb_DNA-binding PF00249.31 GAM28370.1 - 2.9e-05 24.2 0.2 5.2e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAM28370.1 - 0.011 15.9 0.2 0.028 14.6 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain TFIIA PF03153.13 GAM28370.1 - 5.4 6.9 30.0 4.1 7.3 21.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RasGAP PF00616.19 GAM28371.1 - 4.2e-11 43.0 4.9 6e-08 32.6 0.1 2.8 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase SH3_1 PF00018.28 GAM28372.1 - 1.2e-10 40.8 0.2 5.4e-10 38.7 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 GAM28372.1 - 1.9e-08 34.0 0.6 3.6e-08 33.1 0.1 1.6 1 1 1 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 GAM28372.1 - 8.8e-06 25.3 0.0 1.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain His_biosynth PF00977.21 GAM28372.1 - 0.034 13.6 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Histidine biosynthesis protein Isochorismatase PF00857.20 GAM28374.1 - 4.9e-26 92.0 0.0 8.9e-26 91.1 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family Neugrin PF06413.11 GAM28374.1 - 0.042 13.8 0.1 0.05 13.6 0.1 1.1 1 0 0 1 1 1 0 Neugrin ApoA-II PF04711.13 GAM28374.1 - 0.052 13.7 0.3 0.32 11.2 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) AAA_13 PF13166.6 GAM28375.1 - 0.00021 20.1 6.4 0.00039 19.2 6.4 1.4 1 0 0 1 1 1 1 AAA domain RTP1_C1 PF10363.9 GAM28375.1 - 0.016 15.4 2.6 0.033 14.4 0.1 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 GAM28375.1 - 0.042 14.1 0.9 16 6.1 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat Rootletin PF15035.6 GAM28375.1 - 0.079 13.0 18.9 0.16 12.0 18.9 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Exonuc_VII_L PF02601.15 GAM28375.1 - 0.11 12.1 14.9 0.034 13.7 10.7 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 GAM28375.1 - 0.13 12.5 18.3 0.76 10.0 8.6 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding SPX PF03105.19 GAM28375.1 - 0.18 11.7 16.3 0.56 10.1 16.3 1.7 1 1 0 1 1 1 0 SPX domain Snapin_Pallidin PF14712.6 GAM28375.1 - 0.26 11.7 11.2 0.23 11.9 2.7 3.1 2 0 0 2 2 2 0 Snapin/Pallidin DUF4806 PF16064.5 GAM28375.1 - 1.1 9.6 8.7 0.69 10.2 0.8 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4806) DUF1664 PF07889.12 GAM28375.1 - 1.6 8.8 12.5 1.3 9.1 6.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3439 PF11921.8 GAM28375.1 - 1.9 8.5 6.1 4.5 7.3 6.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3450 PF11932.8 GAM28375.1 - 2.5 7.3 16.8 4.4 6.5 8.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 GAM28375.1 - 3 7.7 11.9 5.5 6.8 3.3 3.2 2 1 1 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 GAM28375.1 - 5.2 7.1 26.9 0.25 11.4 1.5 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 GAM28375.1 - 7.3 5.0 5.1 11 4.5 5.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family NUC173 PF08161.12 GAM28376.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 NUC173 domain OmdA PF13376.6 GAM28377.1 - 9.3e-05 22.4 0.1 0.0002 21.3 0.1 1.6 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated INTS5_C PF14838.6 GAM28378.1 - 1.1e-25 90.4 14.5 2.4e-24 86.0 0.3 2.6 2 1 0 2 2 2 2 Integrator complex subunit 5 C-terminus INTS5_N PF14837.6 GAM28378.1 - 7e-05 22.5 1.7 7e-05 22.5 1.7 3.8 3 0 0 3 3 3 1 Integrator complex subunit 5 N-terminus Zip PF02535.22 GAM28378.1 - 0.24 10.6 4.9 0.45 9.7 4.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3439 PF11921.8 GAM28378.1 - 7.2 6.6 11.0 33 4.5 6.3 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3439) TFIIA PF03153.13 GAM28378.1 - 7.5 6.4 21.9 0.42 10.6 14.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Amnionless PF14828.6 GAM28379.1 - 0.029 13.2 2.9 1.2 7.9 0.1 3.0 3 0 0 3 3 3 0 Amnionless T2SSN PF01203.19 GAM28379.1 - 0.038 14.2 0.6 0.12 12.6 0.1 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein N RNase_T PF00929.24 GAM28380.1 - 3.8e-20 73.1 0.0 6.7e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Glyoxalase PF00903.25 GAM28380.1 - 8.2e-09 35.7 0.0 1.8e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF5051 PF16473.5 GAM28380.1 - 5e-08 33.1 0.0 2.8e-07 30.7 0.0 2.2 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like Glyoxalase_2 PF12681.7 GAM28380.1 - 0.0021 18.0 0.1 2.5 8.0 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain 2OG-FeII_Oxy_2 PF13532.6 GAM28381.1 - 8.9e-25 88.0 0.1 1.1e-24 87.8 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIRP PF06584.13 GAM28382.1 - 6.2e-19 68.2 1.2 6.2e-19 68.2 1.2 2.3 2 0 0 2 2 2 1 DIRP Myb_DNA-binding PF00249.31 GAM28382.1 - 0.00057 20.0 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Trp_oprn_chp PF09534.10 GAM28382.1 - 0.19 11.5 0.0 0.57 10.0 0.0 1.8 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Myb_DNA-bind_7 PF15963.5 GAM28382.1 - 0.34 10.8 0.0 0.34 10.8 0.0 3.4 3 0 0 3 3 3 0 Myb DNA-binding like Ras PF00071.22 GAM28383.1 - 1.4e-53 180.8 0.1 1.6e-53 180.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM28383.1 - 8.5e-33 113.1 0.2 1.4e-32 112.5 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM28383.1 - 4.9e-15 55.4 0.0 5.5e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAM28383.1 - 0.00034 20.7 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAM28383.1 - 0.0015 17.9 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAM28383.1 - 0.0038 16.8 0.0 0.016 14.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAM28383.1 - 0.0043 16.5 0.0 0.0091 15.4 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAM28383.1 - 0.007 16.3 0.1 3.8 7.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 GAM28383.1 - 0.041 13.6 0.2 0.14 11.9 0.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation EcpB_C PF18649.1 GAM28383.1 - 0.099 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 EcpB C-terminal domain SET PF00856.28 GAM28384.1 - 3e-07 31.0 0.0 7.4e-06 26.5 0.0 2.6 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 GAM28384.1 - 0.075 13.7 0.1 0.15 12.8 0.1 1.5 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding GATA PF00320.27 GAM28385.1 - 1.8e-15 56.3 2.6 4.4e-15 55.0 2.6 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF5004 PF16395.5 GAM28385.1 - 0.12 12.3 3.3 0.68 9.9 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5004) Methyltransf_4 PF02390.17 GAM28387.1 - 9.9e-37 126.0 0.1 1.3e-36 125.6 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 GAM28387.1 - 1e-05 25.4 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM28387.1 - 0.0017 19.1 0.0 0.004 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM28387.1 - 0.025 15.3 0.6 0.041 14.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.13 GAM28387.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 BTB_2 PF02214.22 GAM28388.1 - 5.4e-13 49.1 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 GAM28388.1 - 0.087 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain ISPD_C PF18706.1 GAM28389.1 - 0.033 13.8 2.4 0.054 13.1 2.4 1.3 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Rcd1 PF04078.13 GAM28390.1 - 4.2e-117 390.0 2.7 5.1e-117 389.8 2.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Kinesin PF00225.23 GAM28391.1 - 5.4e-106 354.3 0.2 5.4e-106 354.3 0.2 2.9 3 0 0 3 3 3 1 Kinesin motor domain Kinesin_assoc PF16183.5 GAM28391.1 - 2e-26 93.2 1.9 1.9e-22 80.3 0.7 5.6 3 2 3 6 6 6 2 Kinesin-associated Microtub_bd PF16796.5 GAM28391.1 - 8.1e-18 64.8 1.5 4.1e-17 62.5 0.0 2.8 2 0 0 2 2 2 1 Microtubule binding PH PF00169.29 GAM28391.1 - 3.5e-09 37.1 1.3 2.9e-08 34.2 0.2 3.0 3 0 0 3 3 3 1 PH domain DUF3694 PF12473.8 GAM28391.1 - 3.6e-08 34.2 0.6 9.5e-07 29.6 0.1 3.5 3 0 0 3 3 3 1 Kinesin protein FHA PF00498.26 GAM28391.1 - 4.8e-07 30.0 0.3 3.2e-06 27.4 0.1 2.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 GAM28391.1 - 7.6e-05 23.0 0.0 0.00029 21.1 0.0 2.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PH_8 PF15409.6 GAM28391.1 - 0.0019 18.4 1.4 0.0035 17.6 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain KIF1B PF12423.8 GAM28391.1 - 0.0053 17.2 2.5 0.018 15.4 0.6 2.9 2 0 0 2 2 2 1 Kinesin protein 1B FNIP PF05725.12 GAM28394.1 - 8.9e-72 237.0 24.6 3.9e-12 46.1 0.2 8.3 5 1 2 8 8 8 8 FNIP Repeat DUF1769 PF08588.10 GAM28394.1 - 0.02 15.1 1.8 7.5 6.8 0.2 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF1769) PTP_tm PF18861.1 GAM28395.1 - 0.00024 21.2 0.2 0.00054 20.0 0.2 1.7 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Beta_helix PF13229.6 GAM28395.1 - 0.00027 20.8 23.9 0.00066 19.6 23.9 1.7 1 1 0 1 1 1 1 Right handed beta helix region DUF4690 PF15756.5 GAM28395.1 - 0.0038 17.8 0.0 0.0071 16.9 0.0 1.4 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 GAM28395.1 - 0.0093 16.1 0.2 0.02 15.0 0.2 1.5 1 0 0 1 1 1 1 Podoplanin DUF4514 PF14986.6 GAM28395.1 - 0.087 12.8 0.9 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) EphA2_TM PF14575.6 GAM28395.1 - 0.26 12.2 0.8 0.47 11.4 0.8 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pentapeptide_4 PF13599.6 GAM28395.1 - 0.36 11.0 3.6 5.9 7.1 0.1 2.5 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) DUF2613 PF11021.8 GAM28395.1 - 3.1 8.0 7.2 0.52 10.5 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) FNIP PF05725.12 GAM28396.1 - 8e-53 176.4 24.7 5.5e-10 39.3 0.1 7.9 5 1 4 9 9 9 8 FNIP Repeat LRR_5 PF13306.6 GAM28396.1 - 0.00018 21.5 2.8 0.038 13.9 1.0 4.1 3 2 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 GAM28397.1 - 1.5e-44 149.9 17.3 3.8e-11 43.0 0.1 7.6 3 2 6 9 9 9 8 FNIP Repeat NUDIX PF00293.28 GAM28398.1 - 1.2e-12 48.0 0.0 1.7e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain ACP_PD PF04336.12 GAM28399.1 - 0.081 13.3 0.0 1.2 9.6 0.0 2.2 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase FNIP PF05725.12 GAM28400.1 - 8.6e-52 173.1 32.9 1.5e-14 53.9 1.3 8.4 8 1 2 10 10 10 8 FNIP Repeat FNIP PF05725.12 GAM28401.1 - 1.1e-75 249.6 61.7 5.5e-16 58.4 1.1 12.5 9 3 5 14 14 14 11 FNIP Repeat DUF1769 PF08588.10 GAM28401.1 - 0.014 15.5 5.4 3.1 8.1 0.0 5.3 4 1 1 5 5 5 0 Protein of unknown function (DUF1769) LRR_4 PF12799.7 GAM28401.1 - 0.24 11.9 19.7 4.1 8.0 1.1 7.6 6 3 2 9 9 9 0 Leucine Rich repeats (2 copies) Glyco_hydro_65C PF03633.15 GAM28401.1 - 0.38 10.7 2.3 18 5.4 0.0 4.6 5 0 0 5 5 5 0 Glycosyl hydrolase family 65, C-terminal domain Coiled PF05710.12 GAM28402.1 - 4.8e-18 65.8 9.5 5.8e-18 65.5 9.5 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 GAM28403.1 - 1e-12 48.7 8.8 1.2e-12 48.5 8.8 1.1 1 0 0 1 1 1 1 Coiled coil RRM_1 PF00076.22 GAM28404.1 - 4e-10 39.4 0.3 1e-09 38.1 0.2 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM28404.1 - 0.00056 19.9 0.0 0.00098 19.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 GAM28404.1 - 0.0066 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif DapH_N PF08503.10 GAM28404.1 - 0.081 13.2 1.7 0.19 12.0 0.3 2.4 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal DUF4481 PF14800.6 GAM28404.1 - 0.79 9.1 3.3 10 5.5 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) Pkinase PF00069.25 GAM28405.1 - 2.5e-45 154.9 0.0 1.1e-44 152.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28405.1 - 8.5e-30 103.9 0.0 3.1e-22 79.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3465 PF11948.8 GAM28405.1 - 0.14 12.0 0.8 0.32 10.9 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) SUIM_assoc PF16619.5 GAM28405.1 - 0.22 11.6 9.4 3.1 7.9 3.1 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 LRS4 PF10422.9 GAM28407.1 - 0.15 11.6 3.4 0.059 12.9 1.0 1.6 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Phage_Orf51 PF06194.11 GAM28407.1 - 0.31 11.1 1.4 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 Fzo_mitofusin PF04799.13 GAM28407.1 - 0.36 10.4 3.2 0.6 9.6 0.2 2.5 2 1 1 3 3 3 0 fzo-like conserved region Adaptin_binding PF10199.9 GAM28407.1 - 2.6 8.7 6.4 0.26 11.9 1.1 2.0 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 7tm_3 PF00003.22 GAM28408.1 - 1.3e-29 103.6 39.9 2.9e-29 102.5 39.9 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PTP_tm PF18861.1 GAM28408.1 - 0.023 14.7 0.6 0.073 13.1 0.6 1.9 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J RhoGAP PF00620.27 GAM28409.1 - 2.6e-28 98.8 0.0 1.5e-27 96.3 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain RhoGEF PF00621.20 GAM28410.1 - 1.3e-41 142.8 3.9 8.1e-41 140.2 3.9 2.4 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAM28410.1 - 1.1e-15 58.1 0.9 3.3e-15 56.5 0.2 2.3 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 GAM28410.1 - 4.8e-10 39.5 2.0 5e-10 39.4 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 GAM28410.1 - 2.1e-06 27.9 0.3 5.6e-06 26.5 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAM28410.1 - 2.8e-05 24.5 7.1 0.00084 19.7 3.7 3.6 2 1 0 2 2 2 1 Pleckstrin homology domain NAD_binding_6 PF08030.12 GAM28411.1 - 1e-26 93.9 0.6 3e-26 92.4 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAM28411.1 - 8.8e-22 77.3 0.0 2.4e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 GAM28411.1 - 3.1e-19 69.3 7.9 3.1e-19 69.3 7.9 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 GAM28411.1 - 9.5e-10 38.8 4.2 2.2e-09 37.7 4.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM28411.1 - 4.2e-09 35.6 4.1 0.0015 18.3 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 GAM28411.1 - 2.7e-08 32.8 4.4 5.8e-05 22.4 2.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 GAM28411.1 - 2.1e-07 30.1 1.7 6.4e-07 28.6 1.7 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 GAM28411.1 - 6.1e-05 22.8 1.4 0.00055 19.7 0.5 2.5 1 1 1 2 2 2 2 EF-hand domain pair ORC6 PF05460.13 GAM28411.1 - 0.78 8.9 6.0 1.4 8.2 6.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NUDIX PF00293.28 GAM28412.1 - 3.2e-10 40.1 0.0 4.6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ank_2 PF12796.7 GAM28413.1 - 3e-37 127.1 4.8 7.1e-09 36.1 0.1 5.8 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28413.1 - 6.7e-34 115.8 2.6 3.9e-07 30.5 0.0 6.7 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM28413.1 - 1.4e-24 85.4 12.5 1.1e-05 25.6 0.0 8.2 8 1 1 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 GAM28413.1 - 2.6e-23 81.8 3.7 6.8e-06 26.3 0.1 7.1 4 2 3 7 7 7 6 Ankyrin repeats (many copies) BTB PF00651.31 GAM28413.1 - 1.3e-17 64.0 1.7 4.4e-06 26.9 0.1 4.7 4 0 0 4 4 4 4 BTB/POZ domain Ank_3 PF13606.6 GAM28413.1 - 6.5e-16 56.8 7.7 0.027 15.0 0.0 9.2 9 1 1 10 10 10 4 Ankyrin repeat DUF3340 PF11818.8 GAM28413.1 - 0.21 11.8 7.5 0.52 10.5 6.8 1.9 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Mucin PF01456.17 GAM28413.1 - 7.8 6.5 28.1 4.4 7.3 13.2 2.9 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4770 PF15994.5 GAM28413.1 - 8.5 6.6 7.3 96 3.1 6.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) PCNA_N PF00705.18 GAM28414.1 - 1.1e-50 170.6 0.2 3.5e-50 169.0 0.4 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 GAM28414.1 - 1.2e-45 154.8 0.1 1.9e-44 150.9 0.0 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 GAM28414.1 - 2.2e-07 30.2 0.2 6.1e-06 25.5 0.2 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 GAM28414.1 - 0.0012 18.4 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 GAM28414.1 - 0.0023 17.1 0.0 0.0054 15.9 0.0 1.5 1 1 0 2 2 2 1 Hus1-like protein Peptidase_M28 PF04389.17 GAM28415.1 - 4.7e-22 78.7 0.1 6.4e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAM28415.1 - 6.7e-09 35.7 0.3 3.6e-08 33.4 0.3 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.22 GAM28415.1 - 0.0045 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 PA domain Synaptobrevin PF00957.21 GAM28415.1 - 0.047 13.5 0.5 0.092 12.6 0.5 1.4 1 0 0 1 1 1 0 Synaptobrevin DUF1127 PF06568.11 GAM28415.1 - 0.22 11.3 0.1 0.5 10.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) Na_H_Exchanger PF00999.21 GAM28416.1 - 2.5e-58 197.7 43.5 3.4e-58 197.2 43.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.12 GAM28416.1 - 1.9e-05 24.5 5.1 1.9e-05 24.5 5.1 2.3 2 0 0 2 2 2 1 Predicted Permease Membrane Region Usp PF00582.26 GAM28416.1 - 0.0047 17.4 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 Universal stress protein family DUF3382 PF11862.8 GAM28416.1 - 0.13 12.6 4.9 0.1 12.9 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Glyco_hydro_7 PF00840.20 GAM28417.1 - 1.2e-198 660.3 12.5 1.3e-198 660.1 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CPSF_A PF03178.15 GAM28418.1 - 9.3e-62 209.2 0.2 1.6e-61 208.4 0.2 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 GAM28418.1 - 2.5e-33 115.5 1.7 2.5e-33 115.5 1.7 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Secretin_N_2 PF07655.13 GAM28418.1 - 6.1 7.5 22.3 0.32 11.6 6.1 3.0 3 0 0 3 3 3 0 Secretin N-terminal domain Ank_2 PF12796.7 GAM28419.1 - 3.9e-53 178.0 4.0 1.3e-18 67.3 0.3 5.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28419.1 - 2.2e-50 168.4 5.5 1.7e-09 38.1 0.1 7.5 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28419.1 - 7.1e-40 130.4 6.8 7.9e-05 22.8 0.1 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 GAM28419.1 - 7.6e-39 130.5 20.0 1.8e-05 25.0 0.3 9.3 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 GAM28419.1 - 1.9e-37 126.9 7.9 5.1e-07 29.8 0.1 7.3 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Homeodomain PF00046.29 GAM28419.1 - 1.9e-18 66.1 1.5 5.2e-18 64.6 1.5 1.8 1 0 0 1 1 1 1 Homeodomain CCSAP PF15748.5 GAM28419.1 - 0.56 10.3 31.2 0.09 12.9 24.0 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Nsp1_C PF05064.13 GAM28420.1 - 1.1e-15 57.4 12.4 1.1e-15 57.4 12.4 2.2 1 1 1 2 2 2 1 Nsp1-like C-terminal region DUF2959 PF11172.8 GAM28420.1 - 0.01 16.0 6.4 0.011 15.9 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) PriC PF07445.12 GAM28420.1 - 0.27 11.1 15.3 0.37 10.7 4.1 2.1 1 1 1 2 2 2 0 Primosomal replication protein priC DUF5420 PF17457.2 GAM28420.1 - 0.37 10.6 2.8 0.62 9.9 2.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5420) Exonuc_VII_L PF02601.15 GAM28420.1 - 1.8 8.0 7.9 3.2 7.2 7.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.12 GAM28420.1 - 1.9 8.5 19.2 5 7.2 6.4 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF4786 PF16027.5 GAM28420.1 - 5 7.7 9.8 5 7.7 7.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4786) TPR_MLP1_2 PF07926.12 GAM28421.1 - 1.1e-26 93.4 18.3 1.1e-26 93.4 18.3 14.8 6 3 9 15 15 15 6 TPR/MLP1/MLP2-like protein Cyclin PF08613.11 GAM28422.1 - 2.1e-21 77.0 0.4 3.7e-21 76.2 0.0 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAM28422.1 - 6.4e-11 42.1 0.0 1.1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2207 PF09972.9 GAM28424.1 - 1.3 7.7 3.9 1.5 7.5 3.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3446 PF11928.8 GAM28425.1 - 1.4 9.3 17.3 0.28 11.5 10.2 2.7 3 0 0 3 3 3 0 Early growth response N-terminal domain RhoGEF PF00621.20 GAM28426.1 - 1.4e-39 136.2 0.3 2.2e-39 135.6 0.3 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF3391 PF11871.8 GAM28426.1 - 0.084 13.4 0.1 4.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) ERbeta_N PF12497.8 GAM28428.1 - 0.13 12.1 0.1 0.36 10.6 0.1 1.7 1 0 0 1 1 1 0 Estrogen receptor beta START PF01852.19 GAM28429.1 - 7.5e-08 32.0 0.3 1.6e-07 30.9 0.3 1.5 1 0 0 1 1 1 1 START domain Tubulin_3 PF14881.6 GAM28431.1 - 1.9e-26 92.8 0.4 4.2e-26 91.7 0.4 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 GAM28431.1 - 6.8e-26 90.9 1.7 6.6e-25 87.7 0.0 3.0 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 GAM28431.1 - 5.3e-08 33.3 0.0 5.2e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain NP1-WLL PF11733.8 GAM28431.1 - 0.037 13.8 0.1 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Non-capsid protein NP1 TBPIP PF07106.13 GAM28432.1 - 0.0044 16.9 0.2 0.013 15.5 0.2 1.7 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Ank_2 PF12796.7 GAM28433.1 - 4.7e-23 81.6 3.5 4.2e-06 27.3 0.1 6.4 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28433.1 - 5.2e-19 68.4 10.4 4.7e-06 27.0 0.0 7.1 8 1 1 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM28433.1 - 6.1e-18 64.7 13.0 0.014 15.7 0.0 11.1 6 4 6 12 12 12 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28433.1 - 1.7e-13 49.4 3.0 14 6.6 0.0 12.4 14 0 0 14 14 14 2 Ankyrin repeat DUF5049 PF16468.5 GAM28433.1 - 0.0034 17.3 0.5 24 4.9 0.0 5.4 6 1 1 7 7 7 1 Domain of unknown function (DUF5049) Ank PF00023.30 GAM28433.1 - 0.0045 17.4 6.7 9.2 6.9 0.0 7.2 6 3 3 9 9 9 1 Ankyrin repeat Rsm1 PF08600.10 GAM28433.1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 Rsm1-like Mic1 PF07035.12 GAM28434.1 - 4.8e-47 159.6 4.0 9.2e-47 158.7 4.0 1.5 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like ANAPC4_WD40 PF12894.7 GAM28434.1 - 0.059 13.7 0.0 0.25 11.6 0.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Shisa PF13908.6 GAM28434.1 - 0.54 10.5 5.6 5.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SGT1 PF07093.11 GAM28435.1 - 1e-130 437.0 21.1 2.6e-125 419.2 6.4 2.0 1 1 1 2 2 2 2 SGT1 protein Ribonuc_L-PSP PF01042.21 GAM28436.1 - 1.8e-28 98.9 0.0 2.4e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Beta_protein PF14350.6 GAM28436.1 - 0.071 12.5 0.0 0.079 12.4 0.0 1.0 1 0 0 1 1 1 0 Beta protein PPR_2 PF13041.6 GAM28437.1 - 5.4e-18 64.9 12.5 1.7e-05 24.9 0.0 5.8 7 0 0 7 7 7 4 PPR repeat family PPR PF01535.20 GAM28437.1 - 3.1e-13 49.0 11.2 0.034 14.4 0.0 5.6 6 0 0 6 6 6 4 PPR repeat PPR_3 PF13812.6 GAM28437.1 - 8.3e-08 32.2 6.6 0.0069 16.4 0.0 4.6 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAM28437.1 - 7e-07 28.8 1.4 0.47 10.2 0.0 4.6 5 0 0 5 5 5 3 PPR repeat ESCRT-II PF05871.12 GAM28437.1 - 0.048 13.9 5.2 0.81 9.9 0.3 3.3 2 1 0 2 2 2 0 ESCRT-II complex subunit Prok-TraM PF09228.10 GAM28437.1 - 0.15 12.5 0.4 1.1 9.7 0.2 2.4 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM Globin PF00042.22 GAM28437.1 - 0.26 11.9 2.0 0.48 11.0 0.0 2.5 3 0 0 3 3 3 0 Globin CREPT PF16566.5 GAM28442.1 - 0.14 12.3 0.8 1 9.5 0.1 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour LcrG PF07216.12 GAM28442.1 - 0.23 11.4 0.6 4 7.4 0.1 2.3 2 0 0 2 2 2 0 LcrG protein Hexokinase_2 PF03727.16 GAM28442.1 - 0.34 10.3 5.1 4.4 6.7 1.3 3.1 2 2 1 3 3 3 0 Hexokinase Kelch_6 PF13964.6 GAM28443.1 - 3.1e-11 43.1 9.6 0.0065 16.7 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM28443.1 - 3.6e-09 36.5 13.3 5.1e-06 26.4 0.1 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM28443.1 - 6.4e-09 35.4 3.5 0.13 12.2 0.3 4.6 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 GAM28443.1 - 1.2e-08 34.4 9.6 0.037 13.6 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_5 PF13854.6 GAM28443.1 - 6.5e-07 29.2 5.0 0.34 10.9 0.2 4.2 4 0 0 4 4 4 3 Kelch motif MeaB PF03308.16 GAM28444.1 - 3.8e-90 301.5 0.1 6.7e-90 300.7 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 GAM28444.1 - 1.9e-06 27.6 0.0 4.9e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 GAM28444.1 - 0.001 18.9 0.1 0.0046 16.8 0.1 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 GAM28444.1 - 0.0023 17.6 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAM28444.1 - 0.0081 16.2 1.9 0.03 14.4 0.1 2.8 2 2 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 GAM28444.1 - 0.011 16.2 0.6 0.024 15.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAM28444.1 - 0.012 15.4 0.7 0.022 14.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAM28444.1 - 0.021 14.6 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAM28444.1 - 0.052 14.1 1.2 0.11 13.0 0.1 2.1 2 1 1 3 3 3 0 ABC transporter AAA_33 PF13671.6 GAM28444.1 - 0.059 13.5 0.1 0.74 10.0 0.1 2.7 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 GAM28444.1 - 0.06 13.9 1.0 0.28 11.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAM28444.1 - 0.068 13.1 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 GAM28444.1 - 0.17 12.2 0.9 0.74 10.1 0.1 2.4 3 0 0 3 3 3 0 AAA domain RPGR1_C PF18111.1 GAM28445.1 - 0.013 15.5 1.1 0.9 9.4 0.4 2.3 2 0 0 2 2 2 0 Retinitis pigmentosa G-protein regulator interacting C-terminal PIP5K PF01504.18 GAM28446.1 - 5.9e-69 232.3 3.7 8.3e-69 231.8 3.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Frizzled PF01534.17 GAM28446.1 - 1.4e-12 47.3 8.1 1.5e-11 44.0 8.1 2.0 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_1 PF00001.21 GAM28446.1 - 5.8e-08 32.4 2.6 8.8e-08 31.8 2.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 GAM28446.1 - 1.6e-05 24.3 8.3 6.8e-05 22.3 5.3 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) RRM_1 PF00076.22 GAM28447.1 - 9.5e-29 99.0 0.0 5.3e-09 35.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sporozoite_P67 PF05642.11 GAM28447.1 - 0.43 8.6 35.1 0.021 12.9 12.8 2.6 2 1 0 2 2 2 0 Sporozoite P67 surface antigen API5 PF05918.11 GAM28447.1 - 0.55 9.0 37.7 0.048 12.5 11.6 3.4 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) A_deaminase PF00962.22 GAM28448.1 - 7.8e-84 281.8 0.0 1.5e-72 244.7 0.0 2.3 2 0 0 2 2 2 2 Adenosine/AMP deaminase FNIP PF05725.12 GAM28449.1 - 8.6e-49 163.5 10.2 1.4e-12 47.6 0.4 5.5 5 0 0 5 5 5 5 FNIP Repeat DUF3752 PF12572.8 GAM28449.1 - 1.8e-17 64.3 14.8 1.8e-17 64.3 14.8 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) Pkinase_Tyr PF07714.17 GAM28453.1 - 6.4e-56 189.5 0.0 9.9e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM28453.1 - 3.3e-51 174.2 0.0 6.5e-51 173.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain COX8 PF02285.15 GAM28454.1 - 2.7 7.9 5.4 0.68 9.9 1.6 2.1 2 1 0 2 2 2 0 Cytochrome oxidase c subunit VIII TipAS PF07739.13 GAM28455.1 - 0.042 14.4 3.6 0.58 10.7 3.4 2.3 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain zf-CHCC PF10276.9 GAM28455.1 - 0.29 11.2 1.5 0.42 10.7 0.6 1.7 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 GAM28455.1 - 2 8.8 8.3 33 4.9 8.3 2.7 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding IZUMO PF15005.6 GAM28455.1 - 4.2 7.9 9.8 9.5 6.7 9.8 1.6 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated PAP2 PF01569.21 GAM28456.1 - 2.4e-19 69.5 6.7 2.4e-19 69.5 6.7 2.3 2 1 0 2 2 2 1 PAP2 superfamily DUF443 PF04276.12 GAM28456.1 - 0.028 14.2 0.5 0.028 14.2 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF443) G_path_suppress PF15991.5 GAM28457.1 - 0.0094 16.1 47.6 0.03 14.5 46.0 2.2 1 1 1 2 2 2 1 G-protein pathway suppressor CEND1 PF15677.5 GAM28457.1 - 0.11 13.1 5.7 0.28 11.7 5.7 1.7 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 V_ATPase_I PF01496.19 GAM28457.1 - 0.29 9.0 12.0 0.36 8.7 12.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mit_KHE1 PF10173.9 GAM28457.1 - 5 7.2 9.4 8 6.5 9.4 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Kelch_1 PF01344.25 GAM28458.1 - 2.6e-33 113.4 1.6 4.3e-07 29.4 0.0 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 GAM28458.1 - 9.1e-33 111.7 5.9 3.9e-05 23.5 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 GAM28458.1 - 1.7e-31 108.0 6.7 7.1e-09 35.5 0.0 5.8 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 GAM28458.1 - 2.2e-31 107.1 5.7 6.8e-07 29.4 0.0 6.0 3 2 3 6 6 6 5 Kelch motif Kelch_3 PF13415.6 GAM28458.1 - 2e-25 88.5 6.8 1.3e-06 28.5 0.0 7.5 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM28458.1 - 3.9e-22 77.3 2.4 3.3e-07 30.0 0.2 6.5 6 0 0 6 6 6 4 Kelch motif F-box-like PF12937.7 GAM28458.1 - 2.3e-06 27.4 0.6 9.3e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAM28458.1 - 8.2e-05 22.4 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 GAM28458.1 - 0.016 15.7 0.5 0.027 15.0 0.5 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A EGF_2 PF07974.13 GAM28459.1 - 0.00014 22.1 17.2 0.00029 21.2 17.2 1.5 1 0 0 1 1 1 1 EGF-like domain LapA_dom PF06305.11 GAM28460.1 - 0.019 14.8 0.3 0.033 14.0 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Phage_holin_2_4 PF16082.5 GAM28460.1 - 0.028 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like CYYR1 PF10873.8 GAM28460.1 - 0.1 13.0 0.1 0.25 11.8 0.1 1.6 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Vpu PF00558.19 GAM28460.1 - 0.12 12.2 1.0 0.21 11.4 1.0 1.4 1 0 0 1 1 1 0 Vpu protein Ras PF00071.22 GAM28461.1 - 7e-55 185.0 0.0 8.6e-55 184.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM28461.1 - 6.5e-19 68.3 0.0 1.2e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM28461.1 - 1.1e-08 34.7 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAM28461.1 - 0.001 19.0 0.1 1 9.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAM28461.1 - 0.0032 17.1 0.0 0.0055 16.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain LcrG PF07216.12 GAM28461.1 - 0.004 17.0 0.1 0.007 16.3 0.1 1.4 1 0 0 1 1 1 1 LcrG protein MMR_HSR1_Xtn PF16897.5 GAM28461.1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 GAM28461.1 - 0.05 13.1 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.6 GAM28461.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Pinin_SDK_N PF04697.13 GAM28461.1 - 0.16 12.7 1.1 0.31 11.7 1.1 1.5 1 1 0 1 1 1 0 pinin/SDK conserved region CH PF00307.31 GAM28462.1 - 9.9e-43 144.8 1.7 3.3e-22 78.7 0.4 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain Cortex-I_coil PF09304.10 GAM28462.1 - 5.7e-39 132.6 22.5 5.7e-39 132.6 22.5 2.8 1 1 1 2 2 2 1 Cortexillin I, coiled coil CAMSAP_CH PF11971.8 GAM28462.1 - 9.1e-05 22.2 0.0 0.67 9.8 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain Macoilin PF09726.9 GAM28462.1 - 0.32 9.5 14.2 0.39 9.2 14.2 1.2 1 0 0 1 1 1 0 Macoilin family ERM PF00769.19 GAM28462.1 - 0.33 10.7 29.2 0.27 11.0 12.0 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4600 PF15372.6 GAM28462.1 - 1.8 9.0 21.1 3.4 8.1 7.0 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4600) FmiP_Thoc5 PF09766.9 GAM28462.1 - 3 7.0 20.1 0.15 11.3 10.4 2.5 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 DUF1664 PF07889.12 GAM28462.1 - 9.8 6.2 9.6 1.1 9.3 3.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Nipped-B_C PF12830.7 GAM28463.1 - 1.1e-40 139.6 3.4 1.1e-40 139.6 3.4 4.0 4 0 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 GAM28463.1 - 2.5e-11 43.6 4.5 7.2e-10 39.0 0.7 3.0 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 GAM28463.1 - 8.1e-06 26.0 13.9 3.2e-05 24.0 0.1 5.5 5 1 1 6 6 5 2 non-SMC mitotic condensation complex subunit 1 CDC45 PF02724.14 GAM28463.1 - 7.1e-05 21.3 5.6 7.1e-05 21.3 5.6 2.8 3 0 0 3 3 3 1 CDC45-like protein PHD PF00628.29 GAM28463.1 - 0.00081 19.2 9.0 0.0027 17.6 9.0 1.9 1 0 0 1 1 1 1 PHD-finger HEAT PF02985.22 GAM28463.1 - 0.0019 18.3 1.8 6.2 7.4 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat Sigma70_ner PF04546.13 GAM28463.1 - 0.0031 17.4 10.2 0.0031 17.4 10.2 3.0 3 0 0 3 3 3 1 Sigma-70, non-essential region YL1 PF05764.13 GAM28463.1 - 0.0044 17.2 12.3 0.0044 17.2 12.3 4.3 5 0 0 5 5 4 1 YL1 nuclear protein zf-HC5HC2H_2 PF13832.6 GAM28463.1 - 0.66 10.2 7.3 21 5.3 4.9 2.9 2 0 0 2 2 2 0 PHD-zinc-finger like domain Vac14_Fab1_bd PF12755.7 GAM28463.1 - 1.1 9.9 4.4 10 6.8 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region PHD_2 PF13831.6 GAM28463.1 - 2 8.0 4.5 5.2 6.7 4.5 1.7 1 0 0 1 1 1 0 PHD-finger zf-piccolo PF05715.13 GAM28463.1 - 3 8.0 5.6 12 6.1 5.6 2.0 1 0 0 1 1 1 0 Piccolo Zn-finger NOA36 PF06524.12 GAM28463.1 - 8.2 5.6 29.8 0.36 10.1 20.3 2.8 2 0 0 2 2 2 0 NOA36 protein Pkinase_Tyr PF07714.17 GAM28464.1 - 1.1e-52 178.9 0.1 1.8e-52 178.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM28464.1 - 4.1e-49 167.3 0.0 8.6e-49 166.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RGS PF00615.19 GAM28464.1 - 3.1e-19 69.4 1.8 2e-18 66.8 1.8 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain Haspin_kinase PF12330.8 GAM28464.1 - 0.0064 15.5 1.9 0.25 10.3 1.9 2.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM28464.1 - 0.027 14.4 0.0 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 GAM28464.1 - 0.038 13.6 0.9 0.063 12.9 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF5427 PF10310.9 GAM28464.1 - 5 6.0 15.0 1.3 7.9 11.3 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5427) DnaJ-X PF14308.6 GAM28465.1 - 8.6e-28 97.2 0.6 8.6e-28 97.2 0.6 2.3 2 2 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAM28465.1 - 2.8e-27 94.6 7.2 9.5e-27 92.9 7.2 2.0 1 0 0 1 1 1 1 DnaJ domain Armet PF10208.9 GAM28465.1 - 0.024 14.6 0.1 0.2 11.6 0.0 2.5 3 0 0 3 3 3 0 Degradation arginine-rich protein for mis-folding ArenaCapSnatch PF17296.2 GAM28465.1 - 0.044 13.2 1.2 17 4.8 0.1 3.3 2 2 2 4 4 4 0 Arenavirus cap snatching domain DUF884 PF05959.11 GAM28465.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) TPR_20 PF14561.6 GAM28465.1 - 0.11 12.9 1.8 0.64 10.4 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 GAM28465.1 - 2.4 8.3 11.4 0.13 12.3 3.4 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Vpu PF00558.19 GAM28466.1 - 0.24 11.2 0.6 0.39 10.5 0.6 1.3 1 0 0 1 1 1 0 Vpu protein Phage_holin_2_4 PF16082.5 GAM28466.1 - 0.24 11.1 0.4 0.72 9.6 0.3 1.8 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Vpu PF00558.19 GAM28467.1 - 0.06 13.1 0.7 0.11 12.3 0.7 1.4 1 0 0 1 1 1 0 Vpu protein EGF_2 PF07974.13 GAM28467.1 - 0.063 13.7 13.7 0.12 12.7 13.7 1.5 1 0 0 1 1 1 0 EGF-like domain LapA_dom PF06305.11 GAM28467.1 - 3.5 7.5 6.9 0.16 11.8 0.9 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DDE_Tnp_1_7 PF13843.6 GAM28468.1 - 3.1e-31 109.0 0.0 6.5e-31 107.9 0.0 1.5 1 1 0 1 1 1 1 Transposase IS4 EGF_2 PF07974.13 GAM28469.1 - 0.51 10.7 17.2 0.083 13.3 13.2 1.8 2 0 0 2 2 2 0 EGF-like domain Vpu PF00558.19 GAM28470.1 - 0.053 13.3 0.8 0.1 12.4 0.8 1.4 1 0 0 1 1 1 0 Vpu protein EGF_2 PF07974.13 GAM28470.1 - 1.3 9.4 18.6 0.19 12.1 14.4 1.9 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 GAM28471.1 - 0.0068 16.8 15.9 0.012 15.9 15.9 1.4 1 0 0 1 1 1 1 EGF-like domain Vpu PF00558.19 GAM28471.1 - 0.063 13.1 1.7 0.11 12.3 1.7 1.3 1 0 0 1 1 1 0 Vpu protein DAP10 PF07213.11 GAM28471.1 - 0.072 13.1 0.8 0.17 11.9 0.8 1.6 1 0 0 1 1 1 0 DAP10 membrane protein EGF PF00008.27 GAM28471.1 - 0.27 11.6 13.5 0.59 10.5 13.5 1.6 1 0 0 1 1 1 0 EGF-like domain TMEM100 PF16311.5 GAM28471.1 - 8.4 6.0 8.8 3.1 7.4 1.8 2.8 3 0 0 3 3 3 0 Transmembrane protein 100 EGF_2 PF07974.13 GAM28472.1 - 0.0008 19.7 15.2 0.0019 18.5 15.2 1.7 1 0 0 1 1 1 1 EGF-like domain Chordopox_E11 PF06138.12 GAM28472.1 - 0.0039 17.5 1.3 0.86 9.9 0.0 3.3 3 0 0 3 3 3 1 Chordopoxvirus E11 protein EGF PF00008.27 GAM28472.1 - 0.048 14.0 14.3 0.12 12.7 14.3 1.8 1 0 0 1 1 1 0 EGF-like domain Vpu PF00558.19 GAM28472.1 - 0.22 11.3 0.3 0.51 10.2 0.3 1.5 1 0 0 1 1 1 0 Vpu protein Glyco_hydro_18 PF00704.28 GAM28473.1 - 7.9e-06 25.8 0.2 2.2e-05 24.4 0.0 1.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 GAM28475.1 - 2.5e-57 194.3 0.0 4.9e-57 193.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28475.1 - 2.8e-57 194.0 0.0 4.2e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM28475.1 - 6.4e-09 35.1 0.0 1.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 GAM28475.1 - 0.00014 21.5 0.1 0.00024 20.7 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL fn3_5 PF06280.12 GAM28475.1 - 0.017 15.8 0.4 0.49 11.1 0.0 3.2 2 1 0 2 2 2 0 Fn3-like domain SKG6 PF08693.10 GAM28475.1 - 4.8 6.7 5.8 0.88 9.0 1.4 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Tir_receptor_C PF07489.11 GAM28476.1 - 0.63 10.0 12.7 1.4 8.8 12.7 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Ecl1 PF12855.7 GAM28476.1 - 2.3 9.4 12.5 0.48 11.6 5.1 2.6 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins CSRNP_N PF16019.5 GAM28477.1 - 0.0073 16.2 5.0 0.0073 16.2 5.0 4.5 3 1 1 4 4 4 2 Cysteine/serine-rich nuclear protein N-terminus zf-RING_2 PF13639.6 GAM28478.1 - 4.6e-07 30.1 15.1 4.6e-07 30.1 15.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-B_box PF00643.24 GAM28478.1 - 3.6e-06 27.0 10.6 3.6e-06 27.0 10.6 2.9 2 1 0 2 2 2 1 B-box zinc finger zf-C3HC4_3 PF13920.6 GAM28478.1 - 0.00012 21.9 12.2 0.00012 21.9 12.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM28478.1 - 0.00094 19.0 14.8 0.00094 19.0 14.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM28478.1 - 0.94 9.8 20.9 0.039 14.2 13.6 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain GMC_oxred_N PF00732.19 GAM28482.1 - 4.2e-37 128.1 0.0 1.1e-36 126.8 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAM28482.1 - 1e-24 87.7 0.5 1.9e-24 86.8 0.5 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAM28482.1 - 2.6e-06 26.8 0.3 0.00065 18.9 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAM28482.1 - 3.3e-05 24.0 0.5 8e-05 22.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAM28482.1 - 0.00092 18.0 0.1 0.0016 17.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAM28482.1 - 0.0016 17.7 0.1 0.0075 15.5 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM28482.1 - 0.0026 17.4 0.7 0.0098 15.5 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAM28482.1 - 0.012 14.9 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAM28482.1 - 0.023 13.8 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 GAM28482.1 - 0.036 13.3 0.1 0.073 12.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 GAM28482.1 - 0.15 11.1 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAM28482.1 - 0.15 11.3 0.3 0.77 9.0 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Q_salvage PF10343.9 GAM28483.1 - 8e-40 137.2 0.0 1.7e-39 136.1 0.0 1.5 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Use1 PF09753.9 GAM28484.1 - 3.5e-23 82.6 15.6 2.5e-22 79.8 15.6 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF4083 PF13314.6 GAM28484.1 - 0.046 13.7 0.7 0.23 11.4 0.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) PhaP_Bmeg PF09602.10 GAM28484.1 - 0.33 10.9 7.8 0.49 10.3 0.8 2.6 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Spore_YhaL PF14147.6 GAM28484.1 - 4.2 7.1 5.2 8.6 6.1 0.3 2.5 2 0 0 2 2 2 0 Sporulation protein YhaL TBCA PF02970.16 GAM28484.1 - 8.9 6.7 10.0 2 8.8 2.6 3.1 4 0 0 4 4 4 0 Tubulin binding cofactor A DUF5383 PF17355.2 GAM28484.1 - 9 6.7 9.2 0.24 11.8 1.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5383) RsfS PF02410.15 GAM28485.1 - 2.1e-19 69.8 0.4 7.6e-19 68.0 0.4 2.0 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation SH3_9 PF14604.6 GAM28486.1 - 1.3e-17 63.3 0.4 2.1e-17 62.7 0.4 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM28486.1 - 6.7e-16 57.6 0.1 1.1e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 GAM28486.1 - 2.7e-14 53.2 0.2 2.7e-14 53.2 0.2 3.2 3 2 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 GAM28486.1 - 1.7e-12 46.8 0.0 2.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FadA PF09403.10 GAM28486.1 - 0.025 15.1 4.7 0.025 15.1 4.7 3.1 3 1 1 4 4 4 0 Adhesion protein FadA MscS_porin PF12795.7 GAM28486.1 - 0.085 12.4 10.8 0.35 10.4 9.0 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Lung_7-TM_R PF06814.13 GAM28487.1 - 8.4e-51 173.0 8.8 1.3e-50 172.4 8.8 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor Cyclin PF08613.11 GAM28488.1 - 1.8e-34 119.4 0.3 1.8e-34 119.4 0.3 2.4 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAM28488.1 - 1.7e-11 44.0 0.0 2.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Macoilin PF09726.9 GAM28488.1 - 1.1 7.7 7.7 1.6 7.2 7.7 1.2 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 GAM28488.1 - 9.4 5.8 11.9 15 5.1 11.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PIG-H PF10181.9 GAM28489.1 - 1.8e-17 63.0 0.9 3.3e-17 62.1 0.9 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Glyco_hydro_38N PF01074.22 GAM28490.1 - 7.9e-83 278.2 0.2 1.3e-82 277.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 GAM28490.1 - 2.9e-27 94.6 0.0 1e-26 92.9 0.0 1.9 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 GAM28490.1 - 2.3e-12 47.4 0.0 3.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain NOC3p PF07540.11 GAM28490.1 - 0.15 12.6 0.0 0.49 10.9 0.0 1.8 2 0 0 2 2 2 0 Nucleolar complex-associated protein GPI2 PF06432.11 GAM28491.1 - 9.6e-92 307.4 19.8 1.2e-91 307.1 19.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Maf1 PF09174.10 GAM28491.1 - 0.93 9.6 4.0 1 9.5 0.6 2.1 2 0 0 2 2 2 0 Maf1 regulator TMEM173 PF15009.6 GAM28491.1 - 3.5 6.7 6.0 0.61 9.2 1.3 2.0 1 1 0 2 2 2 0 Transmembrane protein 173 Androgen_recep PF02166.16 GAM28491.1 - 5.8 5.6 6.2 7.1 5.4 6.2 1.1 1 0 0 1 1 1 0 Androgen receptor Reticulon PF02453.17 GAM28492.1 - 5.7e-06 26.4 12.7 7.1e-06 26.1 12.4 1.3 1 1 0 1 1 1 1 Reticulon DUF639 PF04842.12 GAM28492.1 - 0.013 15.0 2.5 0.018 14.5 2.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF4133 PF13571.6 GAM28492.1 - 1.1 9.7 5.9 0.74 10.2 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) MA-Mit PF09245.10 GAM28493.1 - 0.011 15.2 0.6 0.019 14.5 0.6 1.4 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen LRR_4 PF12799.7 GAM28495.1 - 0.68 10.4 7.7 3.7 8.1 0.1 4.7 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 GAM28496.1 - 0.11 12.9 8.5 0.65 10.5 0.1 5.0 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Duffy_binding PF05424.11 GAM28496.1 - 0.13 12.3 0.3 0.88 9.6 0.0 2.1 2 0 0 2 2 2 0 Duffy binding domain LRR_4 PF12799.7 GAM28497.1 - 0.072 13.5 0.4 2.6 8.6 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) CitT PF12431.8 GAM28497.1 - 0.26 11.7 0.7 1 9.8 0.0 2.5 3 0 0 3 3 3 0 Transcriptional regulator Dicty_CTDC PF00526.18 GAM28502.1 - 0 981.2 960.2 4.3e-11 42.5 13.4 53.4 53 0 0 53 53 53 53 Dictyostelium (slime mold) repeat XhlA PF10779.9 GAM28503.1 - 1 9.6 4.2 0.36 11.1 1.1 1.8 2 0 0 2 2 2 0 Haemolysin XhlA HSP20 PF00011.21 GAM28504.1 - 7.5e-14 51.7 0.1 3.7e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAM28504.1 - 1.1e-05 24.8 0.0 0.081 12.5 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA CS PF04969.16 GAM28504.1 - 0.025 15.6 0.2 0.086 13.9 0.1 2.0 2 1 0 2 2 2 0 CS domain PPO1_KFDV PF12143.8 GAM28504.1 - 0.051 13.7 0.2 0.084 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) Dicty_CTDC PF00526.18 GAM28505.1 - 9.6e-189 610.5 562.5 9.8e-09 35.0 13.8 34.8 33 1 0 34 34 34 34 Dictyostelium (slime mold) repeat DUF21 PF01595.20 GAM28506.1 - 0.021 14.5 4.7 0.7 9.6 0.2 2.6 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain Dak1 PF02733.17 GAM28506.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Dak1 domain TFIIA PF03153.13 GAM28506.1 - 1.2 9.1 10.1 1.5 8.7 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Voltage_CLC PF00654.20 GAM28506.1 - 3.8 6.7 14.2 0.15 11.3 7.3 1.8 1 1 1 2 2 2 0 Voltage gated chloride channel 7TMR-DISM_7TM PF07695.11 GAM28506.1 - 7.1 6.5 29.0 0.024 14.5 16.4 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling Ninjurin PF04923.12 GAM28506.1 - 7.8 6.5 10.3 0.37 10.8 1.5 2.9 2 1 0 2 2 2 0 Ninjurin NDT80_PhoG PF05224.12 GAM28507.1 - 4.7e-16 59.6 0.0 4.7e-16 59.6 0.0 5.0 3 2 0 3 3 3 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.6 GAM28507.1 - 1.3e-12 47.8 0.2 3.3e-12 46.5 0.2 1.8 1 0 0 1 1 1 1 Chaperone of endosialidase Exonuc_VII_L PF02601.15 GAM28507.1 - 0.02 14.5 28.6 0.016 14.8 11.3 2.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Caldesmon PF02029.15 GAM28507.1 - 3.5 6.3 24.5 1.2 7.8 14.0 2.5 2 0 0 2 2 2 0 Caldesmon DUF2975 PF11188.8 GAM28507.1 - 5.6 6.9 5.9 10 6.0 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Zn_dep_PLPC PF00882.18 GAM28508.1 - 0.0063 16.5 0.4 0.0074 16.3 0.4 1.1 1 0 0 1 1 1 1 Zinc dependent phospholipase C Zn_dep_PLPC PF00882.18 GAM28509.1 - 0.025 14.6 0.1 0.031 14.3 0.1 1.1 1 0 0 1 1 1 0 Zinc dependent phospholipase C Nckap1 PF09735.9 GAM28510.1 - 0 1166.0 6.9 0 1165.8 6.9 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Xpo1 PF08389.12 GAM28510.1 - 0.025 14.7 0.2 0.23 11.5 0.0 2.7 1 1 1 2 2 2 0 Exportin 1-like protein EF-hand_1 PF00036.32 GAM28511.1 - 1.2e-14 52.7 0.1 4.8e-06 25.7 0.0 2.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 GAM28511.1 - 7.3e-14 52.0 0.0 1e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAM28511.1 - 1.9e-12 46.1 0.0 2.5e-06 27.0 0.0 2.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 GAM28511.1 - 2.6e-12 46.4 0.0 1.6e-10 40.7 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAM28511.1 - 1.8e-09 36.7 1.1 0.00011 21.6 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 GAM28511.1 - 2.5e-05 24.5 0.0 3.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 GAM28511.1 - 0.0065 16.4 0.0 0.0081 16.1 0.0 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Beta-lactamase2 PF13354.6 GAM28511.1 - 0.0074 15.9 0.0 0.0084 15.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family EF-hand_10 PF14788.6 GAM28511.1 - 0.02 14.8 0.1 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 EF hand UvrA_inter PF17760.1 GAM28511.1 - 0.029 14.4 0.1 0.041 13.9 0.1 1.2 1 0 0 1 1 1 0 UvrA interaction domain SPARC_Ca_bdg PF10591.9 GAM28511.1 - 0.041 14.2 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 GAM28511.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0154) Complex1_LYR PF05347.15 GAM28512.1 - 0.0048 16.9 0.4 0.0076 16.3 0.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) FNIP PF05725.12 GAM28513.1 - 2.8e-86 283.5 22.1 3e-15 56.1 0.0 10.1 10 1 1 11 11 11 10 FNIP Repeat ADH_zinc_N PF00107.26 GAM28514.1 - 4.7e-18 65.4 0.1 7.8e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAM28514.1 - 2e-10 40.5 0.0 4.1e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAM28514.1 - 1.4e-05 26.1 0.0 3.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.25 GAM28514.1 - 0.028 13.8 0.6 0.047 13.1 0.6 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ADH_N_2 PF16884.5 GAM28514.1 - 0.11 12.4 0.1 0.32 10.9 0.1 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase TrkA_N PF02254.18 GAM28514.1 - 0.12 12.6 0.5 0.62 10.3 0.7 2.0 2 0 0 2 2 2 0 TrkA-N domain SPG48 PF14764.6 GAM28515.1 - 5.1e-33 114.0 1.8 5.1e-33 114.0 1.8 2.2 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking KAR9 PF08580.10 GAM28515.1 - 2.9 6.3 12.5 0.033 12.7 0.4 2.7 3 0 0 3 3 3 0 Yeast cortical protein KAR9 DUF4504 PF14953.6 GAM28516.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) F-box PF00646.33 GAM28516.1 - 0.062 13.2 0.5 0.24 11.4 0.5 2.0 1 1 0 1 1 1 0 F-box domain DUF4504 PF14953.6 GAM28517.1 - 0.006 16.0 0.1 0.016 14.6 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4504) Sdh5 PF03937.16 GAM28519.1 - 5.7e-26 90.3 0.5 7.6e-26 89.9 0.5 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase ELP6 PF09807.9 GAM28520.1 - 7.5e-29 100.9 2.3 5.9e-27 94.7 2.3 2.1 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 GAM28520.1 - 2.8e-07 30.3 0.0 5.3e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Elongator subunit Iki1 Ras PF00071.22 GAM28521.1 - 3.5e-51 173.0 0.0 4.7e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM28521.1 - 1.8e-22 79.8 0.0 6.5e-22 78.0 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM28521.1 - 1.7e-07 30.8 0.1 4.8e-07 29.4 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAM28521.1 - 0.032 13.8 0.2 0.46 10.0 0.0 2.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FAD_binding_1 PF00667.20 GAM28522.1 - 5.6e-40 137.3 1.3 7.5e-40 136.9 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 GAM28522.1 - 1.7e-27 96.4 0.0 5.6e-27 94.7 0.0 1.9 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAM28522.1 - 3.6e-20 72.6 0.1 1.2e-19 71.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 GAM28522.1 - 0.0029 17.8 0.0 0.0067 16.7 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.12 GAM28522.1 - 0.0034 17.5 0.0 0.032 14.4 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Glyco_hydro_16 PF00722.21 GAM28523.1 - 6.4e-25 87.6 0.5 8.2e-25 87.3 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 GAM28523.1 - 7.1e-05 21.4 6.5 0.00052 18.5 2.7 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Ank_2 PF12796.7 GAM28525.1 - 4.2e-08 33.7 0.0 0.00085 19.9 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM28525.1 - 4.3e-05 23.7 0.1 0.2 12.0 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28525.1 - 0.0053 17.2 0.0 25 5.9 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 GAM28525.1 - 0.0057 17.2 1.1 8.1 7.2 0.1 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) RRS1 PF04939.12 GAM28526.1 - 1.1e-48 165.2 4.5 1.1e-48 165.2 4.5 1.7 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) RRM_1 PF00076.22 GAM28527.1 - 3.5e-39 132.4 0.0 1.1e-18 66.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAM28527.1 - 3.3e-08 33.2 0.0 0.00025 20.6 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chorion_2 PF03964.15 GAM28527.1 - 0.014 16.3 1.9 0.037 14.9 1.9 1.7 1 0 0 1 1 1 0 Chorion family 2 RNA_bind PF08675.11 GAM28527.1 - 0.017 15.1 1.2 0.36 10.9 0.0 2.7 3 0 0 3 3 3 0 RNA binding domain BRAP2 PF07576.12 GAM28527.1 - 0.025 14.8 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 BRCA1-associated protein 2 RRM_7 PF16367.5 GAM28527.1 - 0.028 14.5 1.1 3.9 7.7 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif Androgen_recep PF02166.16 GAM28527.1 - 0.38 9.5 8.5 0.67 8.7 8.5 1.3 1 0 0 1 1 1 0 Androgen receptor Menin PF05053.13 GAM28527.1 - 1.6 7.0 8.1 2.2 6.5 8.1 1.1 1 0 0 1 1 1 0 Menin RRM_1 PF00076.22 GAM28528.1 - 1.1e-17 63.6 0.1 1.6e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-gamma PF00631.22 GAM28529.1 - 1.3e-14 54.0 0.2 1.4e-14 53.9 0.2 1.0 1 0 0 1 1 1 1 GGL domain F_actin_bind PF08919.10 GAM28529.1 - 0.017 15.2 0.1 0.021 14.9 0.1 1.1 1 0 0 1 1 1 0 F-actin binding RNA_pol_Rpb1_1 PF04997.12 GAM28529.1 - 0.087 12.1 0.0 0.098 12.0 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 G_path_suppress PF15991.5 GAM28529.1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.0 1 0 0 1 1 1 0 G-protein pathway suppressor Peptidase_S28 PF05577.12 GAM28530.1 - 4.8e-128 427.7 2.1 5.5e-128 427.4 2.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 GAM28530.1 - 1.4e-07 30.6 0.3 2.1e-07 30.0 0.3 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 GAM28530.1 - 0.00021 21.0 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM28530.1 - 0.0029 16.9 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM28530.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Dicty_CTDC PF00526.18 GAM28531.1 - 1.5e-177 574.7 444.0 5.1e-11 42.3 11.0 27.4 28 0 0 28 28 28 26 Dictyostelium (slime mold) repeat SGS PF05002.15 GAM28532.1 - 1.1e-25 89.6 0.4 3.4e-25 88.0 0.4 1.9 1 0 0 1 1 1 1 SGS domain TPR_1 PF00515.28 GAM28532.1 - 6.5e-15 54.2 1.9 0.00044 19.9 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat CS PF04969.16 GAM28532.1 - 6.4e-14 52.7 0.4 1.1e-13 51.9 0.4 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 GAM28532.1 - 2.3e-13 49.2 0.2 0.0027 17.7 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM28532.1 - 2.8e-09 36.5 0.0 0.00061 19.4 0.0 3.4 2 1 1 3 3 3 3 TPR repeat ANAPC3 PF12895.7 GAM28532.1 - 1.2e-08 35.0 1.9 2e-08 34.3 1.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAM28532.1 - 7.5e-08 32.0 0.2 0.0012 18.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM28532.1 - 3.1e-06 27.2 0.5 0.0055 17.0 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAM28532.1 - 0.00011 22.3 0.0 0.013 15.6 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAM28532.1 - 0.00022 21.8 0.0 0.0068 17.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM28532.1 - 0.0056 16.7 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 GAM28532.1 - 0.015 15.5 0.1 7.4 6.9 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM28532.1 - 0.037 14.1 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM28532.1 - 0.062 13.8 0.0 7.1 7.2 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.8 GAM28532.1 - 0.1 11.5 0.1 8.4 5.2 0.1 1.9 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 SARG PF15385.6 GAM28532.1 - 0.3 10.3 7.7 0.45 9.7 7.7 1.2 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Rib_recp_KP_reg PF05104.12 GAM28532.1 - 0.79 10.8 11.5 1.9 9.5 11.5 1.7 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region ATPgrasp_ST PF14397.6 GAM28533.1 - 0.0017 17.7 0.0 0.0059 15.9 0.0 1.8 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GHMP_kinases_N PF00288.26 GAM28533.1 - 0.012 15.8 0.5 0.045 14.0 0.5 2.0 1 0 0 1 1 1 0 GHMP kinases N terminal domain RimK PF08443.11 GAM28533.1 - 0.076 12.6 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 GAM28533.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain HNH_5 PF14279.6 GAM28534.1 - 0.92 9.4 7.9 1.5 8.7 0.1 3.9 4 0 0 4 4 4 0 HNH endonuclease DUF3795 PF12675.7 GAM28534.1 - 9.4 6.7 11.1 23 5.5 0.3 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3795) Ribosomal_L16 PF00252.18 GAM28535.1 - 1.9e-41 141.1 0.0 2.8e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CN_hydrolase PF00795.22 GAM28536.1 - 2e-65 220.8 0.0 2.4e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_6 PF13964.6 GAM28537.1 - 7.5e-12 45.1 9.4 9.9e-06 25.7 0.0 5.5 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 GAM28537.1 - 6.7e-09 35.2 8.6 0.075 12.6 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 GAM28537.1 - 1.9e-07 30.9 11.3 0.12 12.4 1.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 GAM28537.1 - 0.0002 21.3 19.6 0.22 11.5 0.2 6.1 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM28537.1 - 0.00023 21.0 4.9 2 8.5 0.0 4.6 4 0 0 4 4 4 2 Kelch motif ArlS_N PF18719.1 GAM28537.1 - 0.099 12.9 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 ArlS sensor domain Kelch_3 PF13415.6 GAM28537.1 - 0.32 11.4 7.1 8.7 6.8 0.2 4.6 5 0 0 5 5 5 0 Galactose oxidase, central domain NAD_binding_6 PF08030.12 GAM28538.1 - 1.9e-34 119.0 0.0 2.8e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAM28538.1 - 5.7e-22 78.2 9.0 5.7e-22 78.2 9.0 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAM28538.1 - 2.1e-19 69.6 0.1 7.7e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain FAD_binding_6 PF00970.24 GAM28538.1 - 0.0033 17.7 0.0 0.0078 16.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Allexi_40kDa PF05549.11 GAM28538.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein NAD_binding_1 PF00175.21 GAM28538.1 - 0.033 14.8 0.0 7.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain ArsC PF03960.15 GAM28540.1 - 0.12 12.4 0.0 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 ArsC family HCNGP PF07818.13 GAM28541.1 - 1.9e-27 95.8 1.1 6e-27 94.1 1.1 1.8 1 0 0 1 1 1 1 HCNGP-like protein BSP_II PF05432.11 GAM28541.1 - 0.002 17.9 16.7 0.002 17.9 16.7 2.1 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) QueH PF02677.14 GAM28541.1 - 0.32 11.1 4.2 2.3 8.3 4.1 2.2 1 1 0 1 1 1 0 Epoxyqueuosine reductase QueH JAB PF01398.21 GAM28542.1 - 4.4e-30 104.1 0.0 1.1e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GAM28542.1 - 1e-27 96.7 2.3 1.9e-27 95.9 2.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF2999 PF11212.8 GAM28542.1 - 0.037 14.3 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) PTPLA PF04387.14 GAM28543.1 - 4.6e-48 163.1 9.7 5.7e-48 162.8 9.7 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA RRM_1 PF00076.22 GAM28544.1 - 1.1e-46 156.5 0.5 2.4e-18 65.7 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 GAM28544.1 - 9.6e-11 41.2 0.1 3.9e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 SAP domain RRM_5 PF13893.6 GAM28544.1 - 2.9e-06 26.9 0.2 0.031 13.9 0.0 3.5 1 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAM28544.1 - 0.0087 15.9 0.0 39 4.2 0.0 3.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif HeH PF12949.7 GAM28544.1 - 0.034 13.9 0.2 0.091 12.5 0.2 1.7 1 0 0 1 1 1 0 HeH/LEM domain Hamartin PF04388.12 GAM28544.1 - 0.6 8.7 71.4 0.28 9.8 47.4 2.1 2 0 0 2 2 2 0 Hamartin protein TFIIA PF03153.13 GAM28544.1 - 3.6 7.5 131.2 0.015 15.3 46.2 3.1 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit HEAT PF02985.22 GAM28545.1 - 9.4e-13 47.2 2.8 0.044 14.1 0.0 8.6 8 0 0 8 8 8 4 HEAT repeat Cnd1 PF12717.7 GAM28545.1 - 4.5e-06 26.8 10.3 0.0053 16.8 0.1 6.1 7 1 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM28545.1 - 0.00024 21.4 0.1 5.6 7.4 0.0 5.8 7 0 0 7 7 7 1 HEAT repeats MMS19_N PF14500.6 GAM28545.1 - 0.002 17.8 3.5 2.8 7.4 0.5 4.9 4 2 1 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 GAM28545.1 - 0.018 15.5 0.0 73 4.0 0.0 5.9 6 0 0 6 6 6 0 HEAT-like repeat Noc2 PF03715.13 GAM28545.1 - 0.026 13.8 0.5 0.073 12.3 0.1 2.1 2 0 0 2 2 2 0 Noc2p family Cohesin_HEAT PF12765.7 GAM28545.1 - 0.045 14.1 2.6 8 6.9 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Aldedh PF00171.22 GAM28545.1 - 0.046 12.2 0.0 0.082 11.4 0.0 1.3 1 0 0 1 1 1 0 Aldehyde dehydrogenase family B56 PF01603.20 GAM28545.1 - 0.13 11.3 7.8 1 8.2 0.1 3.4 4 0 0 4 4 4 0 Protein phosphatase 2A regulatory B subunit (B56 family) UCH PF00443.29 GAM28546.1 - 2.9e-45 154.8 2.3 2.9e-45 154.8 2.3 4.1 4 0 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM28546.1 - 1.2e-30 107.2 1.1 4.8e-30 105.2 1.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 GAM28546.1 - 0.00024 20.8 0.1 0.00066 19.4 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family DUF726 PF05277.12 GAM28547.1 - 1.8e-63 214.5 5.1 1.5e-58 198.4 0.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF726) VPS9 PF02204.18 GAM28547.1 - 2.1e-14 53.6 0.0 6.8e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RAI1 PF08652.11 GAM28547.1 - 0.55 10.5 3.3 0.91 9.8 0.2 2.5 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease Malate_DH PF12434.8 GAM28547.1 - 9.3 6.4 6.3 0.48 10.5 0.5 1.9 2 0 0 2 2 2 0 Malate dehydrogenase enzyme zf-met2 PF12907.7 GAM28548.1 - 7.8e-16 57.9 3.7 1.1e-15 57.4 3.7 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 GAM28548.1 - 7.1e-07 30.0 10.2 7.1e-07 30.0 10.2 1.6 2 0 0 2 2 2 1 4F5 protein family Ric8 PF10165.9 GAM28548.1 - 0.044 12.8 0.1 0.051 12.6 0.1 1.0 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn zf-C2H2_12 PF18658.1 GAM28548.1 - 0.067 12.8 0.1 0.097 12.3 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-C2H2_4 PF13894.6 GAM28548.1 - 0.14 13.1 0.9 0.14 13.1 0.9 1.6 2 0 0 2 2 2 0 C2H2-type zinc finger STT3 PF02516.14 GAM28549.1 - 8.4e-134 447.1 43.4 4e-129 431.7 39.6 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DER1 PF04511.15 GAM28550.1 - 2.9e-56 190.4 17.2 3.4e-56 190.2 17.2 1.0 1 0 0 1 1 1 1 Der1-like family DUF4133 PF13571.6 GAM28550.1 - 0.0044 17.3 0.8 0.0044 17.3 0.8 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4133) RAI16-like PF10257.9 GAM28552.1 - 6.6e-79 265.4 3.1 6.6e-79 265.4 3.1 1.6 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein LIM PF00412.22 GAM28553.1 - 4.7e-11 42.7 7.3 6.7e-11 42.2 7.3 1.2 1 0 0 1 1 1 1 LIM domain zf-C3HC4_2 PF13923.6 GAM28553.1 - 0.53 10.2 5.1 1.1 9.1 0.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 GAM28553.1 - 1 9.3 8.2 0.57 10.1 3.0 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4428 PF14471.6 GAM28553.1 - 1.2 9.2 3.6 1.5 8.8 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Cupin_6 PF12852.7 GAM28553.1 - 8.7 6.0 9.7 0.22 11.2 2.4 2.0 2 1 0 2 2 2 0 Cupin Synaptobrevin PF00957.21 GAM28554.1 - 1e-12 47.7 1.6 1e-12 47.7 1.6 1.5 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 GAM28554.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Ank_2 PF12796.7 GAM28555.1 - 1.1e-24 86.8 13.8 4.8e-08 33.5 0.8 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28555.1 - 4.7e-22 78.1 8.0 7e-05 23.3 0.1 6.3 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM28555.1 - 1.2e-21 76.4 12.8 0.00062 20.0 0.5 8.4 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28555.1 - 2.7e-13 48.8 5.8 1.1 10.0 0.0 9.3 10 0 0 10 10 10 3 Ankyrin repeat Ank PF00023.30 GAM28555.1 - 0.0036 17.7 8.7 1 9.9 0.1 6.3 6 3 0 6 6 6 1 Ankyrin repeat ThiF PF00899.21 GAM28558.1 - 1.2e-30 106.7 0.2 1.6e-30 106.2 0.2 1.1 1 0 0 1 1 1 1 ThiF family E1_4HB PF16191.5 GAM28558.1 - 0.0014 18.7 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 GAM28558.1 - 0.0072 16.7 0.4 0.024 15.1 0.0 1.9 2 1 0 2 2 2 1 Putative NAD(P)-binding Sedlin_N PF04628.13 GAM28558.1 - 0.032 14.4 0.1 0.048 13.8 0.1 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Pkinase PF00069.25 GAM28559.1 - 6.2e-19 68.4 2.8 1.8e-16 60.3 2.8 3.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28559.1 - 5e-14 52.2 0.0 3.9e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM28559.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_1 PF00133.22 GAM28560.1 - 2.1e-55 188.1 8.2 6.8e-33 113.8 8.0 6.0 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 GAM28560.1 - 1.2e-30 106.4 0.0 2.5e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 GAM28560.1 - 7e-30 104.0 0.0 2.9e-21 75.7 0.0 3.8 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAM28560.1 - 2.8e-11 43.6 0.0 5.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 GAM28560.1 - 1.2e-05 24.8 0.0 0.056 12.8 0.1 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 GAM28560.1 - 0.0093 14.9 0.0 0.41 9.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) Zn-ribbon_8 PF09723.10 GAM28560.1 - 0.18 11.9 1.9 1 9.5 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 GAM28560.1 - 0.29 11.2 3.7 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Alpha-amylase PF00128.24 GAM28561.1 - 3.4e-81 273.4 0.0 1.2e-80 271.6 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 GAM28561.1 - 5.5e-10 39.2 0.1 4.6e-07 29.9 0.0 2.5 1 1 1 2 2 2 2 Maltogenic Amylase, C-terminal domain Glyco_hydro_70 PF02324.16 GAM28561.1 - 0.17 10.0 0.2 0.54 8.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 CH PF00307.31 GAM28562.1 - 4.2e-17 62.3 0.2 7.3e-17 61.5 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM28562.1 - 0.0026 17.6 0.1 0.007 16.2 0.1 1.8 1 0 0 1 1 1 1 CAMSAP CH domain Rotamase_3 PF13616.6 GAM28563.1 - 7.1e-19 68.5 0.0 1.4e-18 67.5 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 GAM28563.1 - 4.2e-17 62.9 0.0 5.7e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GAM28563.1 - 2.1e-05 25.4 0.0 2.4e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain RhoGEF PF00621.20 GAM28564.1 - 2.1e-30 106.3 6.5 3e-30 105.8 6.5 1.2 1 0 0 1 1 1 1 RhoGEF domain IQ PF00612.27 GAM28564.1 - 2e-05 24.0 0.3 5.1e-05 22.7 0.3 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif MRP-S33 PF08293.11 GAM28564.1 - 0.019 15.2 0.2 0.048 13.9 0.2 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 HEAT PF02985.22 GAM28565.1 - 2.6e-09 36.5 0.3 0.28 11.5 0.1 5.8 4 0 0 4 4 4 3 HEAT repeat DUF3289 PF11692.8 GAM28565.1 - 0.011 15.3 3.2 0.048 13.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3289) HEAT_EZ PF13513.6 GAM28565.1 - 0.057 13.9 0.0 31 5.2 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat FAD_binding_3 PF01494.19 GAM28566.1 - 7.9e-22 78.0 0.0 9.8e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 GAM28566.1 - 5.7e-07 28.9 0.1 1e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 GAM28566.1 - 1.2e-06 27.7 0.0 0.0078 15.1 0.0 3.3 3 1 1 4 4 4 2 Tryptophan halogenase Lycopene_cycl PF05834.12 GAM28566.1 - 0.00026 20.2 0.3 0.017 14.2 0.1 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAM28566.1 - 0.00054 19.3 0.1 0.0015 17.8 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAM28566.1 - 0.0017 18.0 0.3 0.0046 16.6 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAM28566.1 - 0.0082 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 GAM28566.1 - 0.045 13.8 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF447 PF04289.12 GAM28566.1 - 0.055 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Rubella_E1 PF05748.11 GAM28566.1 - 0.066 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E1 GIDA PF01134.22 GAM28566.1 - 0.11 11.6 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 GAM28566.1 - 0.13 12.6 0.1 0.39 11.0 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Flocculin PF00624.18 GAM28566.1 - 5.7 7.3 7.8 1 9.6 0.4 2.4 2 0 0 2 2 2 0 Flocculin repeat Mcl1_mid PF12341.8 GAM28567.1 - 7.6e-64 215.9 2.3 1.3e-62 211.9 0.0 2.6 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 GAM28567.1 - 3.5e-19 68.8 13.7 1.5e-05 25.7 0.0 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM28567.1 - 3.4e-14 52.9 1.2 0.0003 21.0 0.1 5.8 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 GAM28567.1 - 0.00014 21.8 0.0 0.0027 17.7 0.0 3.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ComS PF17584.2 GAM28567.1 - 0.0034 16.9 3.0 1.7 8.2 0.1 3.6 3 0 0 3 3 3 2 Bacillus competence protein S DUF371 PF04027.13 GAM28567.1 - 0.038 14.0 1.1 0.38 10.7 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF371) RPEL PF02755.15 GAM28567.1 - 0.093 12.5 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 RPEL repeat Methyltransf_11 PF08241.12 GAM28568.1 - 1.5e-22 80.0 0.1 5.1e-22 78.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM28568.1 - 3.8e-19 69.2 0.0 1e-18 67.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM28568.1 - 9.8e-19 67.6 0.0 2.2e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM28568.1 - 1.5e-17 63.9 0.0 2.5e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM28568.1 - 2.2e-16 59.9 0.0 5.1e-16 58.7 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAM28568.1 - 7.2e-12 45.9 0.0 7.2e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 GAM28568.1 - 1.7e-09 37.3 0.0 3.9e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Polyketide_cyc2 PF10604.9 GAM28568.1 - 0.0001 22.6 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MetW PF07021.12 GAM28568.1 - 0.00028 20.5 0.0 0.00059 19.5 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 GAM28568.1 - 0.0004 20.3 0.1 0.0022 17.9 0.0 2.1 2 1 1 3 3 3 1 Hypothetical methyltransferase Methyltransf_15 PF09445.10 GAM28568.1 - 0.0013 18.3 0.1 0.0061 16.2 0.0 2.1 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase COXG PF06240.13 GAM28568.1 - 0.013 15.2 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) DOT1 PF08123.13 GAM28568.1 - 0.022 14.3 0.2 0.072 12.6 0.0 1.9 2 0 0 2 2 2 0 Histone methylation protein DOT1 TehB PF03848.14 GAM28568.1 - 0.042 13.3 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Tellurite resistance protein TehB MTS PF05175.14 GAM28568.1 - 0.054 13.0 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 GAM28568.1 - 0.068 13.2 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 GAM28568.1 - 0.076 12.7 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 RVT_N PF13655.6 GAM28568.1 - 0.34 11.2 1.7 0.81 10.0 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase COesterase PF00135.28 GAM28569.1 - 2e-12 46.8 0.2 6.4e-12 45.1 0.0 1.8 2 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAM28569.1 - 7.6e-11 42.3 0.0 9.3e-11 42.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAM28569.1 - 1e-05 25.1 0.1 0.0064 16.0 0.0 2.3 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 GAM28569.1 - 6.3e-05 22.0 0.0 8.7e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 GAM28569.1 - 7e-05 21.5 0.1 0.00037 19.1 0.0 1.9 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.16 GAM28569.1 - 0.00081 19.2 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Say1_Mug180 PF10340.9 GAM28569.1 - 0.00085 18.3 0.1 0.0012 17.8 0.1 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 GAM28569.1 - 0.0015 19.2 0.0 0.0022 18.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM28569.1 - 0.0094 15.2 0.6 0.063 12.5 0.3 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 GAM28569.1 - 0.025 13.9 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ank_2 PF12796.7 GAM28570.1 - 1.3e-15 57.7 5.5 9.2e-08 32.6 0.5 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28570.1 - 1.3e-11 44.7 2.1 4e-05 24.1 0.3 3.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28570.1 - 1.1e-07 31.6 1.6 0.78 10.5 0.0 5.1 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAM28570.1 - 4e-07 30.2 0.4 0.0042 17.4 0.0 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) WRC PF08879.10 GAM28571.1 - 0.029 14.1 2.4 0.029 14.1 2.4 2.8 1 1 1 2 2 2 0 WRC DUF1936 PF09151.10 GAM28571.1 - 2 8.4 5.4 3.7 7.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Peptidase_C48 PF02902.19 GAM28572.1 - 4.6e-09 36.5 0.2 1.1e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Phage_Gp17 PF17549.2 GAM28573.1 - 1.9 8.5 6.3 0.14 12.2 0.9 1.8 2 0 0 2 2 2 0 Gene Product 17 DUF2606 PF10794.9 GAM28574.1 - 0.039 13.7 0.2 0.06 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Tau95 PF09734.9 GAM28577.1 - 0.037 14.8 0.1 0.05 14.4 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain EAP30 PF04157.16 GAM28578.1 - 7.9e-41 139.9 2.1 7.9e-41 139.9 2.1 2.2 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 GAM28578.1 - 4.7e-15 55.5 0.0 6.1e-14 52.0 0.0 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 TFIIA PF03153.13 GAM28578.1 - 0.0084 16.2 5.7 0.01 15.9 5.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SYF2 PF08231.12 GAM28578.1 - 0.011 16.2 3.8 0.019 15.4 3.8 1.4 1 0 0 1 1 1 0 SYF2 splicing factor RPW8 PF05659.11 GAM28578.1 - 0.014 15.1 1.2 0.029 14.0 0.3 2.0 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TBCC_N PF16752.5 GAM28578.1 - 0.045 14.2 8.3 0.11 12.9 8.3 1.7 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain FTZ PF03867.14 GAM28578.1 - 0.055 13.0 1.4 0.082 12.4 1.4 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Ish1 PF10281.9 GAM28578.1 - 0.072 13.4 0.3 5.6 7.4 0.1 2.8 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein DUF2572 PF10833.8 GAM28578.1 - 0.12 12.2 3.9 0.24 11.2 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) BBL5 PF07289.11 GAM28578.1 - 0.13 11.3 0.0 0.13 11.3 0.0 1.9 1 1 1 2 2 2 0 Bardet-Biedl syndrome 5 protein Tis11B_N PF04553.12 GAM28578.1 - 0.17 12.4 1.4 0.63 10.6 0.0 2.6 2 1 1 3 3 3 0 Tis11B like protein, N terminus Spt20 PF12090.8 GAM28578.1 - 0.28 10.8 11.0 0.48 10.0 11.0 1.4 1 0 0 1 1 1 0 Spt20 family DUF4776 PF16003.5 GAM28578.1 - 0.36 9.8 6.9 0.66 8.9 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) SUIM_assoc PF16619.5 GAM28578.1 - 0.86 9.7 11.2 2.9 8.0 11.2 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ANAPC4_WD40 PF12894.7 GAM28579.1 - 4.6e-07 30.1 0.1 1 9.7 0.0 5.9 5 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Synaptobrevin PF00957.21 GAM28579.1 - 1.6e-05 24.6 2.1 2.8e-05 23.8 2.1 1.4 1 0 0 1 1 1 1 Synaptobrevin WD40 PF00400.32 GAM28579.1 - 0.00059 20.6 1.0 29 5.8 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Tfb4 PF03850.14 GAM28580.1 - 1e-83 281.0 3.8 1.7e-83 280.3 3.8 1.3 1 0 0 1 1 1 1 Transcription factor Tfb4 End3 PF12761.7 GAM28580.1 - 0.089 13.0 0.0 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 ACPS PF01648.20 GAM28581.1 - 9.7e-24 83.7 0.0 1.2e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 GAM28581.1 - 0.0014 18.7 1.4 1.4 9.0 0.1 2.4 2 1 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain RCC1 PF00415.18 GAM28582.1 - 1.1e-73 243.7 18.2 2e-15 57.1 0.9 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM28582.1 - 6.3e-43 143.8 34.1 9.5e-09 34.8 0.1 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RasGAP PF00616.19 GAM28582.1 - 6.7e-35 120.7 16.2 1.2e-20 74.1 0.0 4.0 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase RhoGEF PF00621.20 GAM28582.1 - 2.7e-21 76.6 1.8 2.7e-21 76.6 1.8 2.6 3 0 0 3 3 3 1 RhoGEF domain CAF-1_p150 PF11600.8 GAM28582.1 - 0.035 13.8 33.3 0.091 12.5 33.3 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal U79_P34 PF03064.16 GAM28582.1 - 0.038 13.3 15.7 0.091 12.1 15.7 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3189 PF11385.8 GAM28582.1 - 0.13 12.0 0.0 0.42 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) KcnmB2_inactiv PF09303.10 GAM28582.1 - 0.18 11.6 0.2 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 KCNMB2, ball and chain domain CPSF100_C PF13299.6 GAM28582.1 - 2.1 8.5 10.3 7.8 6.7 10.3 1.9 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 GAM28582.1 - 4.8 6.9 17.4 9.8 5.9 17.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 GAM28582.1 - 5.1 5.8 14.4 13 4.5 14.4 1.6 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EB PF01683.18 GAM28583.1 - 0.008 16.5 1.7 0.008 16.5 1.7 7.6 2 2 5 7 7 7 4 EB module Lustrin_cystein PF14625.6 GAM28583.1 - 0.079 13.4 0.4 0.079 13.4 0.4 8.0 6 2 2 8 8 8 0 Lustrin, cysteine-rich repeated domain Dickkopf_N PF04706.12 GAM28583.1 - 6.7 7.3 80.4 0.14 12.7 5.3 7.5 2 2 6 8 8 8 0 Dickkopf N-terminal cysteine-rich region LRR_6 PF13516.6 GAM28584.1 - 1.5e-09 37.1 45.5 0.068 13.3 0.1 11.0 11 0 0 11 11 11 5 Leucine Rich repeat LRR_1 PF00560.33 GAM28584.1 - 0.00068 19.8 29.0 8.3 7.4 0.6 9.4 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_8 PF13855.6 GAM28584.1 - 0.0041 16.9 34.0 0.21 11.4 4.1 7.6 6 2 1 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 GAM28584.1 - 1.2 9.7 42.5 0.2 12.1 5.6 8.1 3 2 6 9 9 9 0 Leucine Rich repeats (2 copies) Ras PF00071.22 GAM28585.1 - 1.9e-53 180.4 0.1 2.2e-53 180.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM28585.1 - 7.4e-20 71.4 0.0 1.4e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM28585.1 - 4.6e-10 39.2 0.2 5.6e-10 39.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAM28585.1 - 4.4e-05 23.5 0.1 0.0053 16.7 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAM28585.1 - 0.00087 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 GAM28585.1 - 0.046 13.7 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Hist_deacetyl PF00850.19 GAM28586.1 - 4.8e-82 275.9 0.0 6.1e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Patched PF02460.18 GAM28587.1 - 4.4e-83 279.8 24.2 4.4e-83 279.8 24.2 2.5 2 1 1 3 3 3 2 Patched family Sterol-sensing PF12349.8 GAM28587.1 - 1.6e-49 167.7 7.0 1.6e-49 167.7 7.0 3.3 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 GAM28587.1 - 1.8e-24 86.6 7.9 3.4e-24 85.7 7.9 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus ACR_tran PF00873.19 GAM28587.1 - 0.065 10.9 18.4 0.12 10.0 18.4 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Nop14 PF04147.12 GAM28588.1 - 2.5 6.2 5.7 3.6 5.7 5.7 1.4 1 0 0 1 1 1 0 Nop14-like family DUF155 PF02582.14 GAM28589.1 - 6.8e-38 130.5 1.9 4.9e-37 127.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 G_path_suppress PF15991.5 GAM28589.1 - 0.027 14.6 7.7 0.044 13.9 7.7 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor ASD2 PF08687.11 GAM28589.1 - 0.049 13.2 4.8 0.1 12.1 4.8 1.5 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 NPL PF17800.1 GAM28590.1 - 1.6e-14 54.4 0.1 1.6e-14 54.4 0.1 1.9 2 1 0 2 2 2 1 Nucleoplasmin-like domain YL1 PF05764.13 GAM28590.1 - 0.00094 19.4 11.6 0.0013 18.9 11.6 1.2 1 0 0 1 1 1 1 YL1 nuclear protein GAGA_bind PF06217.12 GAM28590.1 - 0.014 15.7 5.8 0.017 15.4 5.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family GREB1 PF15782.5 GAM28590.1 - 2.5 5.1 9.0 3.1 4.8 9.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 GAM28590.1 - 4.3 7.1 15.7 5.6 6.7 15.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCM PF00493.23 GAM28591.1 - 1.9e-102 341.1 0.1 2.9e-102 340.5 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAM28591.1 - 8.1e-36 122.7 0.2 1.6e-35 121.7 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAM28591.1 - 1.5e-25 89.4 0.2 4.3e-25 88.0 0.2 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAM28591.1 - 3.9e-15 56.3 1.0 1e-14 55.0 1.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAM28591.1 - 4.4e-08 32.7 0.0 2.4e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM6_C PF18263.1 GAM28591.1 - 5.4e-07 29.8 2.7 5.4e-07 29.8 2.7 2.2 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain AAA_3 PF07726.11 GAM28591.1 - 6.4e-05 22.8 0.0 0.00038 20.3 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAM28591.1 - 0.0002 21.4 0.0 0.0005 20.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 GAM28591.1 - 0.0032 17.2 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain FAM176 PF14851.6 GAM28591.1 - 0.036 13.7 2.8 0.075 12.7 2.8 1.4 1 0 0 1 1 1 0 FAM176 family Ras_bdg_2 PF14847.6 GAM28591.1 - 0.092 13.1 0.2 0.28 11.5 0.2 1.8 1 0 0 1 1 1 0 Ras-binding domain of Byr2 RXT2_N PF08595.11 GAM28591.1 - 0.16 12.0 5.5 0.32 11.0 5.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 GAM28591.1 - 2.9 7.1 10.9 7 5.9 10.9 1.6 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 GAM28591.1 - 6 7.3 12.5 13 6.2 12.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Transmemb_17 PF09799.9 GAM28592.1 - 0.15 12.6 0.0 0.26 11.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein Filamin PF00630.19 GAM28593.1 - 4.7e-108 355.0 9.1 1.1e-21 77.5 0.1 6.2 5 1 1 6 6 6 6 Filamin/ABP280 repeat CH PF00307.31 GAM28593.1 - 9.8e-43 144.8 0.2 3.9e-22 78.5 0.6 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain Invasin_D3 PF09134.10 GAM28593.1 - 3.7e-18 65.6 9.5 0.015 15.6 0.0 6.3 5 1 1 6 6 6 6 Invasin, domain 3 YtkA PF13115.6 GAM28593.1 - 4.9e-05 23.9 6.0 0.46 11.1 0.0 5.1 5 1 1 6 6 6 1 YtkA-like Y_Y_Y PF07495.13 GAM28593.1 - 9.1e-05 22.3 0.7 0.42 10.6 0.0 4.6 5 0 0 5 5 5 1 Y_Y_Y domain CAMSAP_CH PF11971.8 GAM28593.1 - 0.00019 21.2 0.0 0.94 9.4 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain DUF5060 PF16586.5 GAM28593.1 - 0.00023 21.4 0.3 1.3 9.5 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF5060) Big_6 PF17936.1 GAM28593.1 - 0.00027 21.2 13.2 0.85 9.9 0.2 6.1 5 2 2 7 7 7 2 Bacterial Ig domain Neurexophilin PF06312.12 GAM28593.1 - 0.0033 16.9 0.4 6.1 6.3 0.0 4.0 5 0 0 5 5 5 1 Neurexophilin Big_1 PF02369.16 GAM28593.1 - 0.09 12.8 7.6 14 5.7 0.0 5.2 4 2 1 5 5 5 0 Bacterial Ig-like domain (group 1) Peptidase_U32_C PF16325.5 GAM28593.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain PKD PF00801.20 GAM28593.1 - 0.12 12.3 0.0 2.3 8.1 0.0 3.1 3 0 0 3 3 3 0 PKD domain Cadherin_5 PF17892.1 GAM28593.1 - 1.1 9.3 15.3 7.9 6.5 0.1 5.2 5 1 1 6 6 6 0 Cadherin-like domain Big_3 PF07523.12 GAM28593.1 - 5.2 7.5 8.9 15 5.9 0.0 4.0 5 0 0 5 5 4 0 Bacterial Ig-like domain (group 3) DUF810 PF05664.11 GAM28594.1 - 1.9e-13 49.9 3.5 6.3e-13 48.2 3.5 1.8 1 1 0 1 1 1 1 Plant family of unknown function (DUF810) Phosphodiest PF01663.22 GAM28594.1 - 0.1 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Motilin_assoc PF04643.12 GAM28594.1 - 0.16 11.8 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide DUF4733 PF15878.5 GAM28595.1 - 0.19 12.2 0.1 0.34 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4733) Homeodomain PF00046.29 GAM28596.1 - 0.00032 20.5 1.6 0.00032 20.5 1.6 2.0 2 0 0 2 2 2 1 Homeodomain Arm PF00514.23 GAM28597.1 - 4.4e-13 48.8 4.6 0.0078 16.2 0.1 5.5 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 GAM28597.1 - 1e-10 41.5 6.8 0.001 19.1 0.1 4.6 1 1 5 6 6 6 4 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 GAM28597.1 - 2e-06 27.5 2.1 0.00016 21.2 0.1 2.6 1 1 0 2 2 2 2 Armadillo-like TehB PF03848.14 GAM28597.1 - 0.023 14.1 0.2 5.6 6.3 0.0 3.3 3 1 1 4 4 4 0 Tellurite resistance protein TehB Arm PF00514.23 GAM28598.1 - 5.2e-05 23.1 0.0 0.00025 21.0 0.0 2.2 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat F-box-like PF12937.7 GAM28598.1 - 0.027 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 GAM28598.1 - 0.064 13.1 0.3 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 F-box KASH PF10541.9 GAM28599.1 - 0.075 13.3 7.0 0.099 12.9 7.0 1.1 1 0 0 1 1 1 0 Nuclear envelope localisation domain Lipocalin_3 PF12702.7 GAM28600.1 - 0.12 12.4 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Lipocalin-like Suf PF05843.14 GAM28600.1 - 3.5 7.5 6.4 5.8 6.8 6.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF515 PF04415.12 GAM28600.1 - 8.9 4.6 11.3 14 3.9 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF1128 PF06569.11 GAM28601.1 - 0.0047 16.9 0.1 1.7 8.7 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1128) Colicin-DNase PF12639.7 GAM28601.1 - 3 8.7 8.1 6.1 7.7 0.1 3.0 2 1 1 3 3 3 0 DNase/tRNase domain of colicin-like bacteriocin DUF4286 PF14114.6 GAM28602.1 - 7.2e-18 64.9 0.0 9e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) DEAD PF00270.29 GAM28603.1 - 3.6e-47 160.4 0.0 4.5e-46 156.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM28603.1 - 2e-25 89.3 0.5 4.9e-25 88.0 0.5 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM28603.1 - 1.1e-06 28.8 0.0 4.9e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAM28603.1 - 0.13 11.6 0.0 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Methyltransf_12 PF08242.12 GAM28605.1 - 4.5e-14 53.0 1.0 2.5e-13 50.6 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM28605.1 - 3.6e-12 46.4 0.1 3.1e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM28605.1 - 2e-10 41.2 0.0 4.9e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM28605.1 - 7.2e-09 36.2 0.1 2.7e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM28605.1 - 2.9e-07 30.4 0.3 7.6e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAM28605.1 - 2e-05 24.2 0.0 5.9e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 GAM28605.1 - 0.061 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 GAM28605.1 - 0.077 12.5 0.0 0.31 10.5 0.0 2.0 3 0 0 3 3 3 0 Putative methyltransferase Methyltransf_2 PF00891.18 GAM28605.1 - 0.086 12.1 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_24 PF13578.6 GAM28605.1 - 0.13 13.3 0.0 0.31 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AZUL PF16558.5 GAM28605.1 - 0.43 10.9 6.5 0.86 9.9 6.5 1.5 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Coiled PF05710.12 GAM28607.1 - 0.021 15.6 18.3 0.043 14.7 18.3 1.5 1 1 0 1 1 1 0 Coiled coil DUF3333 PF11812.8 GAM28608.1 - 0.039 14.2 0.3 0.1 12.8 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3333) BAR_3 PF16746.5 GAM28608.1 - 0.078 12.7 4.8 0.12 12.1 4.8 1.2 1 0 0 1 1 1 0 BAR domain of APPL family IL13 PF03487.13 GAM28608.1 - 0.17 11.7 1.5 0.87 9.4 0.2 2.1 2 0 0 2 2 2 0 Interleukin-13 MIF4G PF02854.19 GAM28609.1 - 6.2e-23 81.6 9.4 6.2e-23 81.6 9.4 2.6 2 0 0 2 2 2 1 MIF4G domain Lant_dehydr_N PF04738.13 GAM28609.1 - 0.085 10.9 0.2 0.13 10.3 0.2 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus DUF2408 PF10303.9 GAM28609.1 - 0.28 11.7 5.2 0.84 10.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) UPF0160 PF03690.13 GAM28609.1 - 0.46 10.1 4.2 0.26 10.9 0.7 2.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0160) MCRS_N PF13325.6 GAM28610.1 - 3.5e-11 43.5 2.2 3.6e-11 43.4 0.0 2.1 2 1 0 2 2 2 1 N-terminal region of micro-spherule protein DUF3464 PF11947.8 GAM28610.1 - 0.24 11.1 0.9 0.76 9.5 0.9 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SprA-related PF12118.8 GAM28610.1 - 0.49 9.5 6.8 0.79 8.8 6.8 1.3 1 0 0 1 1 1 0 SprA-related family Phospholip_B PF04916.13 GAM28611.1 - 7.9e-170 565.9 6.8 9.5e-170 565.7 6.8 1.0 1 0 0 1 1 1 1 Phospholipase B VP4_2 PF08935.10 GAM28611.1 - 5 7.8 6.4 0.74 10.4 0.3 2.7 3 0 0 3 3 3 0 Viral protein VP4 subunit PetM PF08041.11 GAM28612.1 - 0.074 12.6 1.7 0.59 9.8 0.1 2.7 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 RhoGAP PF00620.27 GAM28613.1 - 1.8e-33 115.5 0.7 4.4e-33 114.2 0.2 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 GAM28613.1 - 3e-25 88.7 2.1 4.9e-20 72.0 0.1 2.9 3 0 0 3 3 3 2 PH domain F-box-like PF12937.7 GAM28613.1 - 8.4e-09 35.2 0.8 1.8e-08 34.2 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAM28613.1 - 1.6e-06 27.8 0.3 5e-06 26.3 0.3 1.9 1 0 0 1 1 1 1 F-box domain PH_11 PF15413.6 GAM28613.1 - 2.5e-05 24.6 3.7 0.017 15.5 0.1 3.8 2 1 1 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 GAM28613.1 - 0.0069 16.5 0.7 0.041 14.0 0.0 2.7 3 1 0 3 3 3 1 PH domain RGS12_us2 PF16611.5 GAM28613.1 - 0.1 13.0 0.1 0.94 9.9 0.0 2.6 3 0 0 3 3 3 0 Unstructured region between RBD and GoLoco TLE_N PF03920.15 GAM28613.1 - 0.12 12.5 0.4 0.47 10.5 0.3 2.2 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain PH_8 PF15409.6 GAM28613.1 - 0.13 12.6 0.0 0.13 12.6 0.0 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain Foie-gras_1 PF11817.8 GAM28614.1 - 4.2e-38 131.4 6.1 4.2e-38 131.4 6.1 2.6 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 GAM28614.1 - 0.00037 19.4 0.1 0.27 10.0 0.0 2.6 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi TPR_1 PF00515.28 GAM28614.1 - 0.0015 18.3 2.3 0.06 13.2 0.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAM28614.1 - 0.011 15.8 1.8 0.55 10.5 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TRAPPC10 PF12584.8 GAM28614.1 - 0.033 13.9 0.1 1.5 8.5 0.0 3.2 3 0 0 3 3 3 0 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 GAM28614.1 - 0.033 14.2 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Gryzun, putative Golgi trafficking TPR_11 PF13414.6 GAM28614.1 - 0.31 10.8 0.7 1.1 8.9 0.6 2.0 2 0 0 2 2 2 0 TPR repeat RNA_pol_Rpb4 PF03874.16 GAM28615.1 - 1.8e-08 34.7 0.3 2.1e-08 34.5 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF2757 PF10955.8 GAM28615.1 - 0.07 13.4 0.0 0.077 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Plus-3 PF03126.18 GAM28616.1 - 1.4e-25 89.9 0.1 1.4e-25 89.9 0.1 2.4 3 0 0 3 3 3 1 Plus-3 domain DicB PF05358.11 GAM28616.1 - 0.17 12.1 2.4 1.6 8.9 0.1 3.6 4 0 0 4 4 4 0 DicB protein EXS PF03124.14 GAM28617.1 - 1.5e-86 290.7 26.6 1.5e-86 290.7 26.6 1.5 2 0 0 2 2 2 1 EXS family SPX PF03105.19 GAM28617.1 - 4.1e-25 89.5 20.7 4.4e-14 53.2 4.0 3.9 2 1 1 3 3 3 2 SPX domain NAP PF00956.18 GAM28618.1 - 2.1e-08 33.7 19.3 8.3e-06 25.2 9.5 2.7 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) NOA36 PF06524.12 GAM28618.1 - 0.36 10.1 14.7 0.64 9.3 14.7 1.4 1 0 0 1 1 1 0 NOA36 protein MatE PF01554.18 GAM28619.1 - 3.3e-12 46.3 13.7 7.8e-08 32.1 4.8 2.5 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAM28619.1 - 7.8e-05 22.8 5.1 7.8e-05 22.8 5.1 2.1 1 1 1 2 2 2 1 Polysaccharide biosynthesis C-terminal domain Sin_N PF04801.13 GAM28620.1 - 4.8e-93 312.7 12.2 4.8e-93 312.7 12.2 1.7 2 0 0 2 2 2 1 Sin-like protein conserved region ResIII PF04851.15 GAM28620.1 - 0.018 15.1 0.1 0.075 13.0 0.1 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1160 PF06648.11 GAM28620.1 - 0.045 13.8 0.4 0.2 11.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1160) PQ-loop PF04193.14 GAM28621.1 - 2.5e-20 72.0 18.7 1.8e-12 46.8 3.4 3.6 3 1 1 4 4 4 2 PQ loop repeat DUF373 PF04123.13 GAM28621.1 - 8.9 5.6 8.2 18 4.6 8.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Diphthami_syn_2 PF01902.17 GAM28622.1 - 4.4e-44 150.6 0.1 7.7e-44 149.8 0.1 1.4 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 GAM28622.1 - 1.1e-25 89.9 0.0 1.1e-13 51.2 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP ResIII PF04851.15 GAM28623.1 - 5.2e-10 39.6 0.0 1.4e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAM28623.1 - 8.1e-05 22.4 0.1 0.00013 21.7 0.1 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Helicase_C PF00271.31 GAM28623.1 - 0.0012 19.1 0.1 0.0034 17.7 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ank_2 PF12796.7 GAM28624.1 - 2.4e-29 101.7 16.4 7.8e-08 32.8 0.2 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28624.1 - 2.4e-24 85.3 10.3 5.9e-05 23.5 0.1 6.5 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM28624.1 - 4.2e-23 81.1 17.0 0.0019 18.4 0.1 9.3 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28624.1 - 1.2e-18 65.2 4.2 1.3 9.9 0.0 9.3 9 1 1 10 10 10 5 Ankyrin repeat DUF5049 PF16468.5 GAM28624.1 - 2e-08 34.0 7.5 12 5.9 0.0 9.2 3 2 7 10 10 10 2 Domain of unknown function (DUF5049) Ank PF00023.30 GAM28624.1 - 3.9e-07 30.2 3.5 12 6.6 0.0 7.9 2 2 4 6 6 6 2 Ankyrin repeat DUF1428 PF07237.11 GAM28624.1 - 0.021 15.1 0.0 7.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) Lipoprot_C PF08794.10 GAM28624.1 - 0.1 12.6 0.1 30 4.6 0.0 3.4 1 1 2 3 3 3 0 Lipoprotein GNA1870 C terminal like PI3_PI4_kinase PF00454.27 GAM28626.1 - 1.9e-57 194.9 0.4 3.2e-56 190.9 0.4 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAM28626.1 - 3.4e-54 183.0 1.0 7e-54 182.0 1.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 GAM28626.1 - 1.1e-20 74.0 0.0 2.1e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 GAM28626.1 - 3.3e-17 62.6 1.3 1.1e-16 60.9 0.0 2.4 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 GAM28626.1 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) FSA_C PF10479.9 GAM28626.1 - 5.2 5.1 10.6 8.2 4.4 10.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SR-25 PF10500.9 GAM28627.1 - 0.014 15.1 11.0 0.016 14.9 11.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CLN5 PF15014.6 GAM28628.1 - 1.7e-40 139.6 13.6 4.2e-40 138.3 13.6 1.5 1 1 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 CDP-OH_P_transf PF01066.21 GAM28629.1 - 1.5e-17 64.1 0.1 1.5e-17 64.1 0.1 3.7 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase FtsH_ext PF06480.15 GAM28629.1 - 0.12 12.7 0.0 6.4 7.2 0.0 3.2 3 0 0 3 3 3 0 FtsH Extracellular Cation_efflux PF01545.21 GAM28629.1 - 7.2 6.3 15.3 0.62 9.8 0.2 3.4 3 1 0 3 3 3 0 Cation efflux family AAA_12 PF13087.6 GAM28630.1 - 1.7e-43 148.6 0.1 1.7e-43 148.6 0.1 2.1 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 GAM28630.1 - 4.3e-28 98.8 2.9 4.3e-28 98.8 2.9 4.3 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GAM28630.1 - 1.9e-08 34.3 0.0 0.0004 20.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAM28630.1 - 9.1e-08 32.6 0.0 1.2e-06 29.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain zf_CCCH_4 PF18345.1 GAM28630.1 - 6.9e-06 25.9 4.9 3.4e-05 23.7 4.9 2.4 1 0 0 1 1 1 1 Zinc finger domain SAM_1 PF00536.30 GAM28630.1 - 0.0003 21.2 0.0 0.00085 19.7 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CheB_methylest PF01339.17 GAM28630.1 - 0.0044 16.8 0.3 0.0085 15.8 0.3 1.4 1 0 0 1 1 1 1 CheB methylesterase AAA_22 PF13401.6 GAM28630.1 - 0.0046 17.2 0.3 0.5 10.6 0.0 3.5 4 1 0 4 4 4 1 AAA domain DEAD PF00270.29 GAM28630.1 - 0.0066 16.2 0.3 2.1 8.1 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase SAM_PNT PF02198.16 GAM28630.1 - 0.016 15.2 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PhoH PF02562.16 GAM28630.1 - 0.035 13.6 0.0 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 GAM28630.1 - 0.091 13.1 0.4 0.3 11.4 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain TIP41 PF04176.13 GAM28631.1 - 0.034 13.6 0.7 0.049 13.1 0.7 1.4 1 1 0 1 1 1 0 TIP41-like family VASt PF16016.5 GAM28632.1 - 1.4e-29 103.5 0.1 2.8e-29 102.5 0.1 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain SIR2 PF02146.17 GAM28633.1 - 1.2e-57 194.7 0.0 2.4e-57 193.7 0.0 1.5 1 0 0 1 1 1 1 Sir2 family zf-UBP PF02148.19 GAM28633.1 - 4.2e-16 59.0 11.0 4.2e-16 59.0 11.0 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein SSP160 PF06933.11 GAM28633.1 - 0.032 12.5 3.0 0.046 11.9 3.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TT_ORF2 PF02957.15 GAM28633.1 - 0.039 14.9 0.6 0.074 14.0 0.6 1.4 1 0 0 1 1 1 0 TT viral ORF2 ASD2 PF08687.11 GAM28633.1 - 0.078 12.5 1.2 0.12 11.9 1.2 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 FtsH_ext PF06480.15 GAM28633.1 - 0.18 12.1 2.7 0.32 11.4 2.7 1.4 1 0 0 1 1 1 0 FtsH Extracellular DUF3795 PF12675.7 GAM28633.1 - 9.1 6.8 12.5 2.4 8.6 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3795) ELMO_CED12 PF04727.13 GAM28634.1 - 7.7e-42 143.4 1.6 1.6e-41 142.4 1.6 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family Spc24 PF08286.11 GAM28634.1 - 0.69 10.2 7.3 0.058 13.6 0.7 2.6 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF4227 PF14004.6 GAM28635.1 - 0.074 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) Nucleotid_trans PF03407.16 GAM28636.1 - 9.2e-30 104.2 0.0 6.9e-29 101.3 0.0 2.2 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase WD40 PF00400.32 GAM28636.1 - 3.6e-16 59.2 18.4 0.0032 18.3 4.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-B_box PF00643.24 GAM28636.1 - 2.8e-05 24.2 7.6 5.9e-05 23.1 7.6 1.5 1 0 0 1 1 1 1 B-box zinc finger ANAPC4_WD40 PF12894.7 GAM28636.1 - 0.0013 18.9 0.3 0.15 12.4 0.0 3.5 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 GAM28636.1 - 0.025 15.1 0.1 10 6.7 0.0 4.3 4 0 0 4 4 4 0 PQQ-like domain CUE PF02845.16 GAM28637.1 - 1.5e-05 24.6 0.0 5.7e-05 22.7 0.0 2.2 1 0 0 1 1 1 1 CUE domain DUF4248 PF14053.6 GAM28637.1 - 0.039 14.0 0.3 0.38 10.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF4806 PF16064.5 GAM28637.1 - 0.063 13.6 6.3 5 7.5 0.1 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4806) YtxH PF12732.7 GAM28637.1 - 0.23 12.0 0.1 0.23 12.0 0.1 3.5 4 0 0 4 4 4 0 YtxH-like protein mCpol PF18182.1 GAM28637.1 - 0.51 10.7 5.7 0.37 11.2 1.6 2.8 2 1 0 2 2 2 0 minimal CRISPR polymerase domain Reprolysin_3 PF13582.6 GAM28637.1 - 5.9 7.4 12.1 0.15 12.6 3.6 2.4 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like ResIII PF04851.15 GAM28638.1 - 1.8e-13 50.8 0.0 4.2e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAM28638.1 - 6.8e-07 29.2 0.2 1.3e-05 25.1 0.2 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GAM28638.1 - 9.6e-06 25.4 0.0 3.2e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 GAM28638.1 - 0.0052 16.1 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF853 PF05872.12 GAM28638.1 - 0.0096 14.6 0.1 0.015 13.9 0.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 GAM28638.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Helicase_C PF00271.31 GAM28638.1 - 0.066 13.6 0.0 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAM28638.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Kelch_6 PF13964.6 GAM28639.1 - 1.7e-12 47.1 3.8 3.1e-05 24.1 0.1 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 GAM28639.1 - 2.7e-09 36.4 1.0 1 9.0 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 GAM28639.1 - 1.3e-07 31.5 5.6 0.026 14.5 0.0 5.9 6 0 0 6 6 6 2 Galactose oxidase, central domain DUF3196 PF11428.8 GAM28639.1 - 0.0012 18.5 2.1 0.44 10.0 1.4 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3196) Kelch_2 PF07646.15 GAM28639.1 - 0.025 14.6 1.2 66 3.7 0.1 4.4 5 0 0 5 5 5 0 Kelch motif Kelch_3 PF13415.6 GAM28639.1 - 0.11 12.9 6.1 15 6.0 0.1 5.4 6 1 0 6 6 6 0 Galactose oxidase, central domain DUF3023 PF11224.8 GAM28639.1 - 0.17 11.7 0.8 0.49 10.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3023) Kelch_5 PF13854.6 GAM28639.1 - 0.38 10.8 7.5 13 5.9 0.0 3.8 4 0 0 4 4 4 0 Kelch motif GlutR_dimer PF00745.20 GAM28639.1 - 0.57 10.7 3.4 0.31 11.5 0.4 2.1 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain CdvA PF18822.1 GAM28639.1 - 0.68 9.8 4.4 0.47 10.3 0.9 2.3 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Thy1 PF02511.15 GAM28640.1 - 3.3e-50 170.5 0.0 4.5e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase complementing protein Cyclin_N PF00134.23 GAM28641.1 - 1.8e-11 43.9 0.0 5.8e-08 32.5 0.0 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAM28641.1 - 0.0011 19.0 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 GAM28641.1 - 0.03 14.7 0.1 0.065 13.6 0.1 1.6 1 1 0 1 1 1 0 Cyclin C-terminal domain MFS_1 PF07690.16 GAM28642.1 - 7.3e-31 107.4 64.6 6.3e-25 87.9 41.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM28642.1 - 0.00083 18.3 6.5 0.00083 18.3 6.5 2.9 1 1 2 3 3 3 2 Sugar (and other) transporter FNIP PF05725.12 GAM28643.1 - 4.1e-42 142.1 17.0 8e-09 35.5 0.0 9.7 4 3 5 10 10 10 8 FNIP Repeat F-box PF00646.33 GAM28643.1 - 0.011 15.6 0.6 0.011 15.6 0.6 2.2 2 0 0 2 2 2 0 F-box domain DUF4598 PF15370.6 GAM28644.1 - 1.7e-19 70.4 9.0 1.7e-19 70.4 9.0 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4598) DUF3439 PF11921.8 GAM28644.1 - 0.3 11.1 8.5 0.34 10.9 3.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dmrt1 PF12374.8 GAM28644.1 - 1.7 9.1 12.8 4.1 7.9 1.9 2.4 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 LRRFIP PF09738.9 GAM28644.1 - 2.4 7.6 13.7 0.022 14.2 6.1 1.4 2 0 0 2 2 2 0 LRRFIP family Ank_2 PF12796.7 GAM28645.1 - 3.1e-81 268.0 17.4 1.2e-15 57.9 0.0 6.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28645.1 - 3.6e-73 241.0 9.2 1.6e-11 44.5 0.0 9.5 6 2 3 9 9 9 9 Ankyrin repeats (many copies) Sec7 PF01369.20 GAM28645.1 - 6.1e-73 244.4 1.8 9.8e-73 243.7 1.8 1.3 1 0 0 1 1 1 1 Sec7 domain Ank PF00023.30 GAM28645.1 - 4.6e-64 210.2 30.0 0.0001 22.6 0.4 13.8 14 1 0 14 14 13 12 Ankyrin repeat Ank_5 PF13857.6 GAM28645.1 - 9e-64 210.7 15.0 5.2e-09 36.2 0.1 10.7 2 2 10 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28645.1 - 7.3e-61 194.9 13.2 0.00028 21.1 0.0 13.4 13 1 0 13 13 13 12 Ankyrin repeat PH PF00169.29 GAM28645.1 - 5e-25 88.0 0.4 1.2e-24 86.9 0.4 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM28645.1 - 6.9e-07 29.6 0.5 1.8e-06 28.3 0.5 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAM28645.1 - 0.00092 19.5 0.0 0.026 14.8 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 GAM28645.1 - 0.0076 16.3 0.0 0.022 14.8 0.0 1.8 1 1 0 1 1 1 1 PH domain RNA_pol PF00940.19 GAM28645.1 - 0.019 13.8 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 DNA-dependent RNA polymerase PH_6 PF15406.6 GAM28645.1 - 0.021 15.1 0.0 0.31 11.4 0.0 2.5 1 1 1 2 2 2 0 Pleckstrin homology domain Dynamin_N PF00350.23 GAM28646.1 - 0.074 13.1 2.9 0.096 12.7 0.5 2.0 2 0 0 2 2 2 0 Dynamin family Sec62 PF03839.16 GAM28646.1 - 2.1 7.8 9.0 6.6 6.2 2.3 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 TFIIE-A_C PF11521.8 GAM28646.1 - 3 8.2 5.0 22 5.4 0.4 2.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha gag-asp_proteas PF13975.6 GAM28647.1 - 0.049 14.2 1.7 0.14 12.8 0.5 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Usp PF00582.26 GAM28648.1 - 3.1e-18 66.6 0.0 4e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Npa1 PF11707.8 GAM28650.1 - 1.3e-35 123.4 4.6 1.3e-35 123.4 4.6 2.9 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 GAM28650.1 - 4.5e-17 62.3 2.7 4.5e-17 62.3 2.7 3.4 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Utp13 PF08625.11 GAM28650.1 - 0.069 13.1 3.5 1.3 8.9 0.0 4.3 4 1 0 4 4 4 0 Utp13 specific WD40 associated domain ORC6 PF05460.13 GAM28652.1 - 1.8e-07 30.8 0.2 1.8e-07 30.8 0.2 2.9 2 2 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) DUF3915 PF13054.6 GAM28652.1 - 1.3 9.0 3.7 2.3 8.2 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DSPc PF00782.20 GAM28653.1 - 2.7e-27 95.2 4.2 7.2e-26 90.6 0.1 2.9 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAM28653.1 - 2.9e-08 34.0 0.7 2.9e-08 34.0 0.7 3.1 2 2 1 3 3 3 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 GAM28653.1 - 0.0013 19.1 0.0 0.0046 17.2 0.0 2.0 1 0 0 1 1 1 1 Rit1 DUSP-like domain V-SNARE PF05008.15 GAM28654.1 - 3.9e-12 46.4 4.1 3.9e-12 46.4 4.1 2.6 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 GAM28654.1 - 1.2e-08 35.1 2.3 1.2e-08 35.1 2.3 3.5 2 2 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAM28654.1 - 1.2e-05 25.2 0.4 1.2e-05 25.2 0.4 2.3 2 1 0 2 2 2 1 Sec20 TraG_N PF07916.11 GAM28654.1 - 0.00031 19.7 0.2 0.00038 19.4 0.2 1.1 1 0 0 1 1 1 1 TraG-like protein, N-terminal region DUF4407 PF14362.6 GAM28654.1 - 0.0053 16.2 8.7 0.0088 15.4 8.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) DUF1542 PF07564.11 GAM28654.1 - 0.012 15.7 2.8 0.024 14.7 0.2 2.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) VirE PF05272.11 GAM28654.1 - 0.039 13.7 0.1 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 Virulence-associated protein E LMP PF04778.12 GAM28654.1 - 0.053 13.4 2.5 0.11 12.4 0.4 2.2 2 1 0 2 2 2 0 LMP repeated region Vps51 PF08700.11 GAM28654.1 - 0.065 13.3 3.3 0.61 10.2 0.1 2.9 3 0 0 3 3 3 0 Vps51/Vps67 DUF3140 PF11338.8 GAM28654.1 - 0.14 12.6 3.1 0.22 12.0 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3140) Fusion_gly PF00523.18 GAM28654.1 - 0.18 10.0 3.9 0.05 11.8 1.1 1.5 2 0 0 2 2 2 0 Fusion glycoprotein F0 Laminin_II PF06009.12 GAM28654.1 - 0.31 11.0 6.7 1.2 9.1 0.7 2.7 2 1 1 3 3 3 0 Laminin Domain II ATG16 PF08614.11 GAM28654.1 - 0.34 11.1 6.6 0.38 11.0 5.4 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 GAM28654.1 - 0.9 9.2 4.3 15 5.2 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF745) TraF_2 PF13729.6 GAM28654.1 - 1.1 8.6 7.2 1.3 8.3 0.3 2.8 2 1 1 3 3 3 0 F plasmid transfer operon, TraF, protein Phage_GPO PF05929.11 GAM28654.1 - 1.4 8.5 7.5 3.8 7.0 0.9 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Syntaxin_2 PF14523.6 GAM28654.1 - 1.9 8.9 12.5 0.65 10.4 1.5 3.4 2 2 0 3 3 3 0 Syntaxin-like protein DUF2207 PF09972.9 GAM28654.1 - 2 7.1 6.8 0.74 8.5 0.7 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) WH2 PF02205.20 GAM28655.1 - 8.1e-11 41.4 0.8 1.7e-10 40.4 0.8 1.6 1 0 0 1 1 1 1 WH2 motif SH3_9 PF14604.6 GAM28655.1 - 4.2e-07 29.7 0.0 6.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM28655.1 - 2e-06 27.3 0.0 3.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Pox_A_type_inc PF04508.12 GAM28655.1 - 7.8e-06 25.5 1.5 0.057 13.3 0.1 2.2 1 1 1 2 2 2 2 Viral A-type inclusion protein repeat SH3_2 PF07653.17 GAM28655.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.16 GAM28655.1 - 0.016 15.3 0.7 0.025 14.7 0.7 1.3 1 0 0 1 1 1 0 Hr1 repeat CENP-F_leu_zip PF10473.9 GAM28655.1 - 0.025 14.6 0.1 0.037 14.0 0.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.7 GAM28655.1 - 0.03 13.9 3.3 0.043 13.4 3.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain LUC7 PF03194.15 GAM28655.1 - 0.043 13.5 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 LUC7 N_terminus PKcGMP_CC PF16808.5 GAM28655.1 - 0.047 13.6 0.2 0.078 12.8 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Herpes_UL6 PF01763.16 GAM28655.1 - 0.068 11.7 0.2 0.091 11.3 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Spc7 PF08317.11 GAM28655.1 - 0.073 11.9 0.3 0.1 11.5 0.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FNIP PF05725.12 GAM28656.1 - 3.8e-81 267.0 26.8 2.7e-14 53.0 0.0 9.0 7 1 2 9 9 9 9 FNIP Repeat DUF1769 PF08588.10 GAM28656.1 - 0.0052 17.0 5.6 2.6 8.3 0.0 6.1 3 2 4 7 7 6 1 Protein of unknown function (DUF1769) Glyco_hydro_25 PF01183.20 GAM28657.1 - 7e-08 32.9 0.4 1e-07 32.3 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Tmemb_185A PF10269.9 GAM28658.1 - 5.7e-06 26.2 22.5 6.1e-06 26.1 9.6 3.2 2 1 0 2 2 2 2 Transmembrane Fragile-X-F protein Na_H_Exchanger PF00999.21 GAM28659.1 - 2.3e-55 188.0 49.5 2.6e-55 187.8 49.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2427 PF10348.9 GAM28659.1 - 0.0014 18.3 0.9 0.0014 18.3 0.9 3.4 2 1 2 4 4 4 1 Domain of unknown function (DUF2427) Amino_oxidase PF01593.24 GAM28660.1 - 1.5e-69 235.5 0.0 1.7e-69 235.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAM28660.1 - 5.4e-17 61.8 0.2 1.1e-16 60.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAM28660.1 - 3.6e-07 30.1 0.0 1.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAM28660.1 - 7.5e-06 25.3 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAM28660.1 - 3.2e-05 23.5 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAM28660.1 - 0.00018 20.3 0.0 0.00036 19.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 GAM28660.1 - 0.00051 20.5 0.0 0.002 18.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAM28660.1 - 0.00053 19.3 0.0 0.0012 18.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM28660.1 - 0.0014 17.9 0.2 0.0026 17.1 0.2 1.4 1 1 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAM28660.1 - 0.0055 16.0 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAM28660.1 - 0.0078 15.3 0.0 0.027 13.6 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A GDI PF00996.18 GAM28660.1 - 0.014 14.0 0.3 0.035 12.6 0.0 1.8 2 0 0 2 2 2 0 GDP dissociation inhibitor FAD_binding_3 PF01494.19 GAM28660.1 - 0.068 12.4 0.1 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAM28660.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Enkurin PF13864.6 GAM28661.1 - 0.0013 19.1 5.2 0.0026 18.2 5.2 1.5 1 1 0 1 1 1 1 Calmodulin-binding Prominin PF05478.11 GAM28661.1 - 0.097 10.6 5.0 0.12 10.3 5.0 1.2 1 0 0 1 1 1 0 Prominin FAD-SLDH PF12318.8 GAM28661.1 - 0.21 11.7 0.2 0.22 11.6 0.2 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase ZapB PF06005.12 GAM28661.1 - 0.21 12.1 7.1 0.67 10.4 4.6 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF883 PF05957.13 GAM28661.1 - 0.24 12.0 2.2 1.1 10.0 0.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) KMP11 PF03037.16 GAM28661.1 - 0.26 12.1 5.2 0.39 11.5 5.2 1.5 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 Atg14 PF10186.9 GAM28661.1 - 0.38 9.8 7.5 0.42 9.7 7.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 GAM28661.1 - 1.3 9.1 5.4 1.6 8.8 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 GAM28662.1 - 1.7e-54 185.0 0.1 1.7e-54 185.0 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28662.1 - 2.2e-21 76.3 0.0 3.9e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAM28662.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4639 PF15479.6 GAM28662.1 - 6.5 5.6 20.2 10 4.9 20.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) DHR-2 PF06920.13 GAM28663.1 - 2.4e-134 448.9 11.2 4.4e-134 448.0 11.2 1.4 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 GAM28663.1 - 1.6e-24 86.8 4.6 2.9e-23 82.7 4.6 2.6 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Alk_phosphatase PF00245.20 GAM28664.1 - 6.4e-81 272.4 7.0 1.2e-80 271.5 7.0 1.5 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 GAM28664.1 - 4.1e-05 23.1 0.2 7.5e-05 22.2 0.2 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 GAM28665.1 - 2.2e-86 290.4 2.8 4.1e-86 289.5 2.8 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 GAM28665.1 - 0.00071 19.0 0.1 0.0013 18.2 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily SKG6 PF08693.10 GAM28665.1 - 0.04 13.3 3.7 0.11 11.9 3.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MLANA PF14991.6 GAM28665.1 - 0.17 12.2 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A Peptidase_S49 PF01343.18 GAM28666.1 - 8.3e-65 217.4 1.2 9e-42 142.6 0.7 2.3 2 0 0 2 2 2 2 Peptidase family S49 SDH_sah PF01972.16 GAM28666.1 - 1.5e-06 27.4 0.0 2.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 GAM28666.1 - 0.0039 17.1 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Clp protease Imm40 PF15569.6 GAM28666.1 - 0.084 13.0 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Immunity protein 40 DUF3395 PF11875.8 GAM28667.1 - 5.1e-42 143.4 0.7 9.6e-42 142.5 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 GAM28667.1 - 8.2e-20 70.7 1.3 8.2e-20 70.7 1.3 2.6 3 0 0 3 3 3 1 DnaJ domain Raptor_N PF14538.6 GAM28667.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.7 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Ras PF00071.22 GAM28668.1 - 1e-14 54.4 0.2 2.4e-13 50.0 0.1 2.2 2 0 0 2 2 2 1 Ras family Roc PF08477.13 GAM28668.1 - 1.2e-06 28.8 0.0 0.0012 19.0 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAM28668.1 - 0.045 13.8 0.0 0.17 12.0 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pyrophosphatase PF00719.19 GAM28669.1 - 2.3e-49 167.3 0.2 2.8e-49 167.0 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Arf PF00025.21 GAM28670.1 - 8.6e-32 110.0 0.0 1e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM28670.1 - 3.1e-08 33.8 0.1 1.1e-07 32.1 0.0 1.9 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 GAM28670.1 - 1.6e-05 24.4 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 GAM28670.1 - 0.00019 21.1 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 GAM28670.1 - 0.00069 19.1 0.0 0.00082 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAM28670.1 - 0.0013 18.0 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit NOG1 PF06858.14 GAM28670.1 - 0.027 14.2 0.1 0.06 13.1 0.0 1.6 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 GAM28670.1 - 0.029 14.5 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Acetyltransf_2 PF00797.17 GAM28671.1 - 8.5e-38 130.5 0.1 1.1e-37 130.1 0.1 1.1 1 0 0 1 1 1 1 N-acetyltransferase V-SNARE_C PF12352.8 GAM28672.1 - 0.44 10.9 5.1 0.75 10.1 0.6 2.9 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus TFIIS_C PF01096.18 GAM28673.1 - 3.2e-17 62.1 3.8 3.2e-17 62.1 3.8 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 GAM28673.1 - 0.0013 18.6 12.1 0.02 14.7 3.1 3.7 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit Ogr_Delta PF04606.12 GAM28673.1 - 0.0055 16.7 2.5 0.0055 16.7 2.5 2.4 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.7 GAM28673.1 - 0.0065 16.4 6.9 0.022 14.7 1.4 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-C4_Topoisom PF01396.19 GAM28673.1 - 0.088 12.6 7.5 0.67 9.8 1.6 3.5 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Baculo_LEF5_C PF11792.8 GAM28673.1 - 0.23 11.2 2.2 0.48 10.1 1.1 2.0 1 1 1 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-ribbon_3 PF13248.6 GAM28673.1 - 0.46 10.0 9.0 2.4 7.7 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 GAM28673.1 - 0.59 10.2 10.1 0.42 10.7 0.5 2.9 2 1 1 3 3 3 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 GAM28673.1 - 2.5 8.5 4.9 8.2 6.8 0.0 3.0 3 0 0 3 3 3 0 zinc-ribbon Zn-ribbon_8 PF09723.10 GAM28673.1 - 4.3 7.5 14.2 18 5.5 1.3 3.9 3 1 1 4 4 4 0 Zinc ribbon domain C1_4 PF07975.12 GAM28673.1 - 6.6 7.1 8.7 6 7.2 3.3 3.7 2 1 1 3 3 3 0 TFIIH C1-like domain PA26 PF04636.13 GAM28674.1 - 3.1e-148 494.3 0.1 4.1e-148 494.0 0.1 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF3808 PF10300.9 GAM28675.1 - 7.5e-33 114.0 8.0 7.5e-33 114.0 8.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3808) TPR_8 PF13181.6 GAM28675.1 - 0.0059 16.7 15.6 1.2 9.5 0.1 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM28675.1 - 0.019 15.1 14.4 1.7 9.0 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM28675.1 - 0.024 14.5 4.0 14 5.7 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAM28675.1 - 0.045 14.3 1.3 16 6.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAM28675.1 - 0.049 13.3 3.9 0.67 9.6 0.0 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat-like domain Phage_base_V PF04717.12 GAM28675.1 - 0.078 12.9 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector TPR_12 PF13424.6 GAM28675.1 - 0.078 13.3 4.8 4.1 7.8 0.3 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM28675.1 - 0.1 13.3 12.4 0.43 11.3 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.25 GAM28676.1 - 3.2e-61 207.0 0.1 5e-61 206.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28676.1 - 1.6e-27 96.4 0.0 2.8e-27 95.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM28676.1 - 0.00014 21.3 0.0 0.00032 20.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAM28676.1 - 0.00017 20.5 1.9 0.00017 20.5 1.9 2.4 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAM28676.1 - 0.0003 20.2 0.1 0.0003 20.2 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM28676.1 - 0.0024 17.8 0.0 0.098 12.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAM28676.1 - 0.0093 15.6 2.8 0.014 15.0 0.4 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase Velvet PF11754.8 GAM28676.1 - 0.013 15.4 5.9 0.35 10.8 1.6 2.2 2 0 0 2 2 2 0 Velvet factor Chorion_2 PF03964.15 GAM28676.1 - 4.6 8.1 10.6 1.9 9.4 4.2 2.3 2 0 0 2 2 2 0 Chorion family 2 CCDC84 PF14968.6 GAM28676.1 - 4.6 6.8 9.9 0.41 10.2 1.6 2.1 2 0 0 2 2 2 0 Coiled coil protein 84 DUF1635 PF07795.11 GAM28676.1 - 6.5 6.5 13.5 2.5 7.9 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Macoilin PF09726.9 GAM28676.1 - 7.9 4.9 24.7 0.65 8.5 7.3 2.1 2 0 0 2 2 2 0 Macoilin family SR-25 PF10500.9 GAM28676.1 - 8.4 5.9 37.0 0.12 12.0 16.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ank_4 PF13637.6 GAM28677.1 - 1.3e-84 277.6 14.0 6.6e-12 45.7 0.0 12.1 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM28677.1 - 8.8e-82 269.8 18.6 3.3e-17 62.8 0.1 7.2 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM28677.1 - 2.2e-72 230.3 0.1 7.2e-06 26.0 0.1 13.3 13 0 0 13 13 13 10 Ankyrin repeat Ank PF00023.30 GAM28677.1 - 1.1e-71 234.3 7.9 4.3e-08 33.3 0.0 13.0 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 GAM28677.1 - 1.6e-59 197.2 1.8 7.3e-09 35.7 0.0 9.7 3 1 3 9 9 9 9 Ankyrin repeats (many copies) CH PF00307.31 GAM28677.1 - 1.9e-17 63.4 0.6 4.6e-17 62.2 0.6 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Phage_T7_Capsid PF05396.11 GAM28677.1 - 0.00075 19.8 2.2 0.58 10.5 0.1 3.2 3 0 0 3 3 3 2 Phage T7 capsid assembly protein DUF4106 PF13388.6 GAM28677.1 - 0.0013 18.0 2.5 0.0025 17.1 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) CDC24 PF06395.11 GAM28677.1 - 0.014 15.7 0.4 0.032 14.5 0.4 1.6 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.8 GAM28677.1 - 0.014 15.2 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 CAMSAP CH domain Shigella_OspC PF06128.11 GAM28677.1 - 0.035 13.8 0.3 0.25 11.0 0.1 2.4 2 0 0 2 2 2 0 Shigella flexneri OspC protein DUF3718 PF12514.8 GAM28677.1 - 0.038 14.1 0.0 16 5.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3718) Thioredoxin_8 PF13905.6 GAM28677.1 - 0.094 13.1 0.1 0.36 11.2 0.1 2.0 1 0 0 1 1 1 0 Thioredoxin-like PK PF00224.21 GAM28678.1 - 4.2e-144 479.7 7.7 5.7e-144 479.3 7.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAM28678.1 - 4.2e-26 91.5 2.3 6.6e-26 90.8 0.4 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAM28678.1 - 0.0076 15.4 0.3 0.013 14.6 0.3 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PTS_2-RNA PF01885.16 GAM28679.1 - 1.4e-63 214.3 0.2 1.6e-63 214.0 0.2 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF2999 PF11212.8 GAM28680.1 - 0.056 13.7 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Pro_CA PF00484.19 GAM28681.1 - 4.7e-50 169.9 0.1 6.2e-50 169.5 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Peptidase_S10 PF00450.22 GAM28682.1 - 7.5e-102 341.8 3.6 1e-101 341.4 3.6 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.32 GAM28683.1 - 1.4e-50 168.1 38.0 1.1e-06 29.2 0.4 11.5 11 0 0 11 11 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM28683.1 - 8.1e-28 96.6 9.0 6.6e-05 23.1 0.0 9.5 5 2 4 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain DUF4062 PF13271.6 GAM28683.1 - 3.4e-13 49.8 0.0 1.1e-12 48.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) eIF2A PF08662.11 GAM28683.1 - 3.2e-07 30.4 3.6 0.31 10.9 0.1 4.8 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.6 GAM28683.1 - 9.8e-07 29.3 0.0 5.7e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain APAF1_C PF17908.1 GAM28683.1 - 1e-06 28.8 0.2 1.7e-05 24.8 0.2 2.8 1 1 0 1 1 1 1 APAF-1 helical domain AAA_22 PF13401.6 GAM28683.1 - 5.2e-06 26.8 0.0 2.3e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain WD40_like PF17005.5 GAM28683.1 - 0.0051 16.2 6.4 0.57 9.4 0.2 3.9 3 1 1 4 4 4 2 WD40-like domain NACHT PF05729.12 GAM28683.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Glyco_hydro_32C PF08244.12 GAM28683.1 - 0.021 14.9 0.3 0.061 13.3 0.3 1.8 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal ABC_tran PF00005.27 GAM28683.1 - 0.035 14.6 0.7 7.7 7.0 0.0 3.2 3 0 0 3 3 3 0 ABC transporter Diphtheria_T PF02764.14 GAM28683.1 - 0.12 12.4 0.0 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Diphtheria toxin, T domain Phage_tail_2 PF06199.11 GAM28683.1 - 0.14 12.3 2.6 0.22 11.6 1.6 1.8 2 0 0 2 2 1 0 Phage tail tube protein MAT1 PF06391.13 GAM28683.1 - 0.23 11.3 5.2 0.45 10.3 5.2 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 CCDC106 PF15794.5 GAM28683.1 - 0.61 9.8 9.0 12 5.5 7.2 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Tir_receptor_N PF07490.11 GAM28683.1 - 7.2 6.3 6.1 35 4.1 3.8 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus SAPIS-gp6 PF16722.5 GAM28685.1 - 1 9.8 4.6 2.3 8.7 4.6 1.5 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus SWIRM-assoc_2 PF16496.5 GAM28685.1 - 1.7 7.4 9.8 3 6.6 9.8 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CTP_transf_1 PF01148.20 GAM28688.1 - 8.8e-06 25.7 10.7 2e-05 24.5 5.5 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family B12D PF06522.11 GAM28689.1 - 1.2e-05 25.0 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aminotran_1_2 PF00155.21 GAM28690.1 - 1.6e-83 280.9 0.0 1.9e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1289 PF06945.13 GAM28691.1 - 1.3e-19 69.7 1.7 1.4e-19 69.6 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) BCAS2 PF05700.11 GAM28692.1 - 9.4e-57 192.0 14.7 1.1e-56 191.9 14.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) 6PF2K PF01591.18 GAM28692.1 - 0.0025 17.2 1.3 0.0025 17.2 1.3 2.0 1 1 2 3 3 3 1 6-phosphofructo-2-kinase Thioredoxin_8 PF13905.6 GAM28692.1 - 0.93 9.9 5.7 0.64 10.4 2.9 2.0 1 1 1 2 2 2 0 Thioredoxin-like Plk4_PB2 PF18409.1 GAM28692.1 - 2.4 8.9 6.9 0.76 10.5 2.9 2.0 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 APG6_N PF17675.1 GAM28692.1 - 5.4 7.5 17.1 0.6 10.6 11.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Clathrin_lg_ch PF01086.17 GAM28693.1 - 4.7e-16 59.6 19.8 1.9e-15 57.5 19.8 1.8 1 1 0 1 1 1 1 Clathrin light chain Phage_gp53 PF11246.8 GAM28693.1 - 0.15 11.7 0.8 0.2 11.3 0.8 1.4 1 0 0 1 1 1 0 Base plate wedge protein 53 Hid1 PF12722.7 GAM28693.1 - 7.9 4.5 10.6 8.4 4.4 10.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATP_bind_3 PF01171.20 GAM28694.1 - 7.3e-17 61.7 0.0 1.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 GAM28694.1 - 2.3e-14 52.6 6.2 2.3e-14 52.6 6.2 3.6 3 0 0 3 3 3 1 Zinc-ribbon CTU2 PF10288.9 GAM28694.1 - 0.0071 16.6 2.5 0.0071 16.6 2.5 3.0 3 1 0 3 3 3 1 Cytoplasmic tRNA 2-thiolation protein 2 VPS13 PF16908.5 GAM28695.1 - 7.7e-64 215.7 2.7 7.7e-64 215.7 2.7 4.2 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 GAM28695.1 - 3.1e-57 193.2 0.9 3.1e-57 193.2 0.9 4.3 5 0 0 5 5 5 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 GAM28695.1 - 9.7e-49 165.9 35.4 8.6e-45 153.0 5.7 7.0 5 1 1 6 6 6 4 Repeating coiled region of VPS13 SHR-BD PF06650.12 GAM28695.1 - 2.8e-48 164.7 8.9 6e-48 163.6 2.0 3.3 2 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 GAM28695.1 - 8.4e-39 132.3 2.1 1.2e-37 128.6 2.0 3.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 GAM28695.1 - 3e-09 37.1 0.1 6.7e-08 32.8 0.1 2.9 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain AMP-binding PF00501.28 GAM28696.1 - 1.4e-88 297.4 0.0 1.7e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAM28696.1 - 3.9e-16 59.8 0.1 7.3e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 GAM28696.1 - 0.0043 16.0 0.1 0.023 13.6 0.1 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter PC_rep PF01851.22 GAM28697.1 - 3.1e-37 125.2 24.6 3.1e-07 30.5 0.3 9.3 10 0 0 10 10 10 7 Proteasome/cyclosome repeat RPN2_C PF18004.1 GAM28697.1 - 4e-32 111.4 10.7 6.9e-32 110.6 10.7 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 GAM28697.1 - 1.5e-16 60.6 1.7 9.1e-11 42.0 0.1 4.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 GAM28697.1 - 0.0019 18.3 0.6 6.8 7.2 0.1 4.6 4 0 0 4 4 4 1 HEAT repeat Clathrin_H_link PF13838.6 GAM28697.1 - 0.017 15.0 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Clathrin-H-link DUF2620 PF10941.8 GAM28697.1 - 0.1 12.7 0.1 0.35 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF2620 RR_TM4-6 PF06459.12 GAM28697.1 - 0.29 10.9 8.5 0.53 10.1 8.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4770 PF15994.5 GAM28697.1 - 2.8 8.2 8.0 5.6 7.2 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FAM176 PF14851.6 GAM28697.1 - 3.3 7.4 6.3 8.6 6.0 6.3 1.6 1 0 0 1 1 1 0 FAM176 family Connexin PF00029.19 GAM28697.1 - 9.8 5.9 6.1 17 5.1 6.1 1.3 1 0 0 1 1 1 0 Connexin AF-4 PF05110.13 GAM28698.1 - 0.37 8.8 10.8 0.4 8.7 10.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4718 PF15842.5 GAM28698.1 - 2.3 8.0 7.7 2.7 7.8 7.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4718) RRP36 PF06102.12 GAM28699.1 - 6.7e-44 149.8 25.0 6.7e-44 149.8 25.0 2.2 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 CCT_2 PF09425.10 GAM28699.1 - 0.076 12.9 3.6 0.11 12.4 0.9 2.3 2 0 0 2 2 2 0 Divergent CCT motif PPR_2 PF13041.6 GAM28700.1 - 0.0021 18.2 0.1 0.0077 16.4 0.1 2.0 1 0 0 1 1 1 1 PPR repeat family Nucleotid_trans PF03407.16 GAM28700.1 - 0.46 10.4 3.6 1.5 8.7 1.7 2.2 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase DUF2935 PF11155.8 GAM28701.1 - 0.54 10.6 6.8 35 4.7 6.8 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) CorA PF01544.18 GAM28701.1 - 5.4 6.2 12.3 2.9 7.1 6.9 2.6 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein Antimicrobial19 PF08225.11 GAM28702.1 - 4.3 7.1 5.2 14 5.4 0.2 3.0 3 0 0 3 3 3 0 Pseudin antimicrobial peptide ALS2CR8 PF15299.6 GAM28703.1 - 0.002 18.0 0.0 0.02 14.8 0.0 2.0 1 1 0 1 1 1 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Tri3 PF07428.11 GAM28703.1 - 0.0078 15.2 0.0 0.06 12.3 0.0 1.9 2 0 0 2 2 2 1 15-O-acetyltransferase Tri3 PmrD PF11183.8 GAM28703.1 - 0.18 11.9 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD Haspin_kinase PF12330.8 GAM28704.1 - 1.7e-08 33.9 1.3 1.7e-08 33.9 1.3 2.3 1 1 0 2 2 2 1 Haspin like kinase domain Pkinase PF00069.25 GAM28704.1 - 5.9e-07 29.1 3.4 1e-06 28.4 2.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28704.1 - 0.00027 20.3 0.4 0.00083 18.7 0.2 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase TERB2 PF15101.6 GAM28704.1 - 1 9.4 13.1 0.94 9.5 1.2 2.6 2 0 0 2 2 2 0 Telomere-associated protein TERB2 PBP_sp32 PF07222.12 GAM28704.1 - 6.7 6.1 13.8 8 5.8 7.4 2.4 2 0 0 2 2 2 0 Proacrosin binding protein sp32 SLBP_RNA_bind PF15247.6 GAM28705.1 - 1.9e-30 104.8 5.9 3.5e-30 103.9 5.9 1.5 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain DUF4637 PF15470.6 GAM28705.1 - 0.22 11.2 5.8 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Aminotran_5 PF00266.19 GAM28706.1 - 1.6e-33 116.2 0.0 2.8e-33 115.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.17 GAM28706.1 - 1.3e-26 93.2 0.2 2.9e-26 92.0 0.1 1.6 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 GAM28706.1 - 5.9e-24 84.3 0.0 1e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF4326 PF14216.6 GAM28706.1 - 0.069 13.9 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4326) SAM_1 PF00536.30 GAM28707.1 - 1.5e-07 31.7 0.0 4.1e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM28707.1 - 2.9e-07 30.5 0.0 7.9e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) UQ_con PF00179.26 GAM28708.1 - 2.4e-40 137.4 0.1 3.8e-40 136.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ORC6 PF05460.13 GAM28708.1 - 0.025 13.9 12.6 0.032 13.5 12.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Dicty_REP PF05086.12 GAM28708.1 - 0.19 9.6 18.4 0.25 9.3 18.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 GAM28708.1 - 0.35 10.8 4.1 0.67 9.9 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DDHD PF02862.17 GAM28708.1 - 1.1 9.4 6.8 1.4 9.0 6.8 1.1 1 0 0 1 1 1 0 DDHD domain Med13_C PF06333.12 GAM28708.1 - 1.4 8.1 10.4 1.7 7.8 10.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain NOA36 PF06524.12 GAM28708.1 - 2.9 7.1 14.1 3.6 6.8 14.1 1.1 1 0 0 1 1 1 0 NOA36 protein Tir_receptor_C PF07489.11 GAM28708.1 - 3.7 7.5 13.3 5.2 7.0 13.3 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus MCM_bind PF09739.9 GAM28708.1 - 8.8 4.6 13.7 7.1 5.0 12.2 1.5 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor Presenilin PF01080.17 GAM28708.1 - 9.3 4.9 10.9 11 4.6 10.9 1.1 1 0 0 1 1 1 0 Presenilin DEAD PF00270.29 GAM28709.1 - 6.5e-49 166.1 0.0 2.2e-48 164.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM28709.1 - 3.6e-28 98.1 0.0 1.7e-27 96.0 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAM28709.1 - 5.5e-07 29.8 0.9 2e-06 27.9 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SprA-related PF12118.8 GAM28709.1 - 0.25 10.4 7.6 0.44 9.6 7.6 1.3 1 0 0 1 1 1 0 SprA-related family GAS2 PF02187.17 GAM28710.1 - 4.5e-05 23.5 0.0 4.5e-05 23.5 0.0 3.0 3 0 0 3 3 3 1 Growth-Arrest-Specific Protein 2 Domain Ge1_WD40 PF16529.5 GAM28711.1 - 1.2e-12 47.5 0.0 1.7e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4795 PF16043.5 GAM28711.1 - 0.18 11.4 12.5 0.19 11.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) GlutR_dimer PF00745.20 GAM28711.1 - 5.7 7.5 6.9 13 6.3 0.5 3.1 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Aldo_ket_red PF00248.21 GAM28712.1 - 1.8e-44 152.1 0.0 2e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TraB PF01963.17 GAM28714.1 - 2.9e-16 60.2 0.6 3.1e-15 56.8 0.6 2.1 1 1 0 1 1 1 1 TraB family Pirin_C PF05726.13 GAM28715.1 - 0.086 13.2 0.4 1.3 9.4 0.0 3.0 3 0 0 3 3 3 0 Pirin C-terminal cupin domain Ank_4 PF13637.6 GAM28716.1 - 2.8e-21 75.6 0.0 2.5e-05 24.7 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM28716.1 - 4e-21 75.4 0.9 2.4e-08 34.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM28716.1 - 7.4e-15 53.6 0.1 0.01 16.2 0.1 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 GAM28716.1 - 6.1e-13 48.7 0.4 0.0014 18.9 0.1 3.7 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM28716.1 - 1.3e-11 44.4 1.2 0.00057 20.2 0.1 5.3 6 0 0 6 6 6 2 Ankyrin repeat DDE_3 PF13358.6 GAM28717.1 - 3.5e-23 82.0 0.1 5.8e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease eIF-5_eIF-2B PF01873.17 GAM28717.1 - 0.027 14.3 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain found in IF2B/IF5 HEAT PF02985.22 GAM28719.1 - 1.6e-07 31.0 1.4 0.25 11.7 0.0 5.9 5 1 0 5 5 5 2 HEAT repeat Vac14_Fab1_bd PF12755.7 GAM28719.1 - 0.039 14.6 0.0 5.4 7.7 0.0 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Sec8_exocyst PF04048.14 GAM28719.1 - 0.091 12.6 5.9 2.1 8.2 1.0 3.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Prefoldin PF02996.17 GAM28719.1 - 0.37 10.7 8.8 0.51 10.3 0.6 3.5 2 1 1 3 3 3 0 Prefoldin subunit DUF1054 PF06335.12 GAM28719.1 - 0.68 9.8 4.5 4.4 7.2 4.5 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) YabA PF06156.13 GAM28719.1 - 2.3 8.9 6.1 11 6.7 3.6 3.1 2 0 0 2 2 2 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 GAM28719.1 - 9 6.4 13.1 15 5.7 3.6 4.0 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding MMR_HSR1 PF01926.23 GAM28720.1 - 2e-23 82.6 0.4 4.5e-23 81.5 0.4 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAM28720.1 - 2e-11 44.2 1.6 1.8e-05 24.8 0.1 3.0 1 1 1 2 2 2 2 Dynamin family KH_2 PF07650.17 GAM28720.1 - 3e-10 39.8 0.3 7.2e-10 38.6 0.3 1.7 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 GAM28720.1 - 1.7e-09 37.4 1.6 8e-09 35.2 1.6 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAM28720.1 - 1e-08 35.0 0.8 2.6e-05 23.9 0.2 2.8 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAM28720.1 - 8.4e-08 32.3 0.9 0.0021 18.0 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 GAM28720.1 - 1.6e-07 30.9 2.1 3.8e-07 29.6 2.0 1.7 1 1 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 GAM28720.1 - 0.0018 18.0 0.4 2.2 8.0 0.1 3.4 1 1 1 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 GAM28720.1 - 0.0051 17.0 0.9 0.059 13.6 0.9 2.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 GAM28720.1 - 0.034 13.7 2.9 0.19 11.3 1.1 2.4 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 GAM28720.1 - 0.045 14.3 0.2 0.14 12.6 0.2 1.9 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 GAM28720.1 - 0.051 14.0 0.1 0.15 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 GAM28720.1 - 0.32 11.0 3.6 0.57 10.2 0.2 2.8 3 1 1 4 4 3 0 C-terminal region of MMR_HSR1 domain NOG1 PF06858.14 GAM28720.1 - 0.55 10.0 2.8 0.74 9.6 0.5 2.3 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) ACOX PF01756.19 GAM28721.1 - 5e-16 58.8 0.1 8.4e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 GAM28721.1 - 1.5e-15 57.2 0.0 2.7e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 GAM28721.1 - 6.2e-09 36.5 0.0 1.2e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 GAM28721.1 - 0.00041 20.6 0.0 0.0044 17.2 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAM28721.1 - 0.002 18.8 0.0 0.0047 17.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Pyridoxal_deC PF00282.19 GAM28723.1 - 2.3e-14 52.9 0.0 5e-14 51.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAM28723.1 - 1e-11 44.5 0.3 3.1e-11 42.9 0.1 1.8 2 1 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAM28723.1 - 0.00014 21.2 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II IQ_SEC7_PH PF16453.5 GAM28723.1 - 0.07 13.1 0.5 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 PH domain Peptidase_M20 PF01546.28 GAM28724.1 - 4.5e-38 131.0 0.0 5.7e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAM28724.1 - 4e-17 62.1 0.0 7.4e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Hexapep PF00132.24 GAM28725.1 - 1.7e-07 30.7 14.4 0.0012 18.5 0.4 4.5 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 GAM28725.1 - 0.003 16.6 1.7 0.005 15.8 0.5 1.7 1 1 1 2 2 2 1 L-fucokinase DUF4954 PF16314.5 GAM28725.1 - 0.23 9.6 0.4 0.29 9.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 GAM28725.1 - 1.9 8.3 11.6 2.2 8.1 3.3 3.8 4 1 2 6 6 6 0 Hexapeptide repeat of succinyl-transferase Hep_59 PF07052.11 GAM28726.1 - 0.015 16.1 0.1 0.029 15.1 0.1 1.4 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Ctr PF04145.15 GAM28726.1 - 0.24 12.0 4.7 0.38 11.4 4.4 1.7 1 1 0 1 1 1 0 Ctr copper transporter family Pex24p PF06398.11 GAM28726.1 - 4.9 6.0 10.0 2 7.3 2.5 2.2 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin AIRC PF00731.20 GAM28727.1 - 1.1e-61 206.7 1.1 3e-61 205.3 1.1 1.8 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 GAM28727.1 - 1.8e-49 167.6 0.0 3.1e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain SAICAR_synt PF01259.18 GAM28727.1 - 4.3e-47 160.8 0.0 7.7e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 SAICAR synthetase PurK_C PF17769.1 GAM28727.1 - 1.3e-14 53.6 0.2 3.2e-14 52.4 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 GAM28727.1 - 2.1e-05 24.1 0.1 5.3e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 GAM28727.1 - 0.0046 16.5 0.1 0.027 14.0 0.1 2.3 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus PALP PF00291.25 GAM28727.1 - 0.015 14.8 0.1 0.015 14.8 0.1 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 GAM28727.1 - 0.024 14.0 0.0 0.068 12.5 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TMEM52 PF14979.6 GAM28728.1 - 0.019 14.9 3.2 0.088 12.7 1.1 2.3 2 0 0 2 2 2 0 Transmembrane 52 YesK PF14150.6 GAM28728.1 - 0.051 13.8 1.1 0.051 13.8 1.1 2.5 2 1 1 3 3 3 0 YesK-like protein Borrelia_rep PF03183.13 GAM28728.1 - 0.12 12.4 1.8 0.32 11.1 1.8 1.7 1 0 0 1 1 1 0 Borrelia repeat protein DUF5345 PF17280.2 GAM28728.1 - 0.18 11.8 0.3 0.18 11.8 0.3 2.4 3 1 1 4 4 4 0 Family of unknown function (DUF5345) DUF2516 PF10724.9 GAM28728.1 - 0.51 10.6 4.6 0.16 12.2 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) LAB_N PF07578.11 GAM28728.1 - 0.95 9.6 4.4 4 7.6 0.0 3.2 3 1 0 3 3 3 0 Lipid A Biosynthesis N-terminal domain HIG_1_N PF04588.13 GAM28729.1 - 9.4e-10 38.6 0.2 1.2e-09 38.2 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region GATase PF00117.28 GAM28730.1 - 7.3e-10 38.9 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I HTS PF04204.16 GAM28730.1 - 0.00075 18.5 0.0 0.0055 15.7 0.0 2.0 2 0 0 2 2 2 1 Homoserine O-succinyltransferase Glyco_hydro_39 PF01229.17 GAM28731.1 - 4.6e-111 371.8 2.1 9.3e-111 370.8 2.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 MACPF PF01823.19 GAM28733.1 - 1.7e-21 77.3 2.3 3e-21 76.5 2.3 1.4 1 0 0 1 1 1 1 MAC/Perforin domain Ank_2 PF12796.7 GAM28735.1 - 6.8e-12 45.8 12.8 0.00035 21.1 0.0 7.5 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM28735.1 - 7.1e-08 32.6 5.2 12 6.3 0.0 7.1 7 1 0 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28735.1 - 6.5e-05 23.0 4.2 33 5.5 0.1 8.1 8 0 0 8 8 8 1 Ankyrin repeat Ank_4 PF13637.6 GAM28735.1 - 0.0012 19.4 4.4 67 4.2 0.0 7.3 5 1 2 7 7 7 0 Ankyrin repeats (many copies) HNF-1B_C PF04812.13 GAM28737.1 - 0.0077 16.1 2.0 0.014 15.2 2.0 1.5 1 1 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Ac110_PIF PF07280.11 GAM28737.1 - 0.015 15.0 0.2 0.033 14.0 0.2 1.5 1 0 0 1 1 1 0 Per os infectivity factor AC110 Resolvase PF00239.21 GAM28738.1 - 1.4e-06 28.5 0.2 2.4e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain Phage_TAC_8 PF10666.9 GAM28738.1 - 0.11 12.8 0.1 0.24 11.7 0.1 1.7 1 1 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 Peptidase_C48 PF02902.19 GAM28741.1 - 5.1e-10 39.6 0.1 1.2e-09 38.3 0.0 1.6 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Gemini_V2 PF01524.17 GAM28741.1 - 0.009 16.2 0.2 1.9 8.7 0.1 2.4 2 0 0 2 2 2 2 Geminivirus V2 protein Peptidase_C57 PF03290.13 GAM28741.1 - 0.065 12.0 0.4 0.083 11.6 0.4 1.2 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase DUF4672 PF15716.5 GAM28742.1 - 0.12 12.0 0.2 0.16 11.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) HJURP_C PF12347.8 GAM28743.1 - 0.028 14.4 0.2 0.028 14.4 0.2 2.5 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat GTP_EFTU PF00009.27 GAM28743.1 - 0.11 12.1 0.6 0.14 11.6 0.5 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DEC-1_N PF04625.13 GAM28745.1 - 0.82 8.6 4.9 1.2 8.0 4.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF5423 PF17461.2 GAM28746.1 - 0.0049 15.8 3.7 0.0053 15.7 3.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5423) zf-BED PF02892.15 GAM28746.1 - 0.062 13.3 3.0 0.32 11.1 0.9 2.5 2 0 0 2 2 2 0 BED zinc finger Chromo PF00385.24 GAM28747.1 - 1.9e-14 53.3 0.5 1.9e-14 53.3 0.5 2.5 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 GAM28747.1 - 8.1e-11 42.2 0.0 1.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Peptidase_M24_C PF16188.5 GAM28747.1 - 0.053 13.6 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 RT_RNaseH PF17917.1 GAM28748.1 - 1.8e-23 82.8 0.4 6.2e-23 81.1 0.1 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAM28748.1 - 9.6e-21 73.7 0.8 1.9e-20 72.8 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GAM28748.1 - 3.8e-16 58.9 2.1 6.4e-16 58.2 2.1 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_Tnp_4 PF13359.6 GAM28749.1 - 8e-06 25.6 0.7 1.6e-05 24.6 0.1 1.8 2 1 0 2 2 2 1 DDE superfamily endonuclease Asp_protease_2 PF13650.6 GAM28751.1 - 6.1e-06 26.8 0.0 1.6e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GAM28751.1 - 0.00046 20.7 0.1 0.0019 18.7 0.1 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 GAM28751.1 - 0.00048 20.4 0.1 0.002 18.4 0.1 2.0 1 0 0 1 1 1 1 Retroviral aspartyl protease HSBP1 PF06825.12 GAM28751.1 - 0.0064 16.3 0.2 0.02 14.8 0.2 1.8 1 0 0 1 1 1 1 Heat shock factor binding protein 1 RVP_2 PF08284.11 GAM28751.1 - 0.021 14.6 0.3 0.021 14.6 0.3 2.5 3 0 0 3 3 3 0 Retroviral aspartyl protease DUF4172 PF13776.6 GAM28751.1 - 0.17 12.2 2.1 0.52 10.7 2.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) HSBP1 PF06825.12 GAM28752.1 - 0.0019 18.0 0.2 0.0043 16.9 0.2 1.6 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF4106 PF13388.6 GAM28752.1 - 6.1 6.0 14.8 7.9 5.6 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Myb_DNA-binding PF00249.31 GAM28754.1 - 1e-20 73.6 2.6 1.7e-11 44.1 0.1 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain SWIRM PF04433.17 GAM28754.1 - 1.1e-19 70.5 1.1 3.9e-19 68.8 0.0 2.5 2 1 0 2 2 2 1 SWIRM domain JAB PF01398.21 GAM28754.1 - 9.4e-11 41.7 0.0 9.4e-11 41.7 0.0 3.2 3 1 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 GAM28754.1 - 2e-10 40.5 0.1 2.3e-09 37.0 0.1 2.6 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 GAM28754.1 - 2.6e-10 40.4 5.3 1.1e-05 25.6 0.3 3.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAM28754.1 - 1.6e-06 27.9 3.2 1.6e-06 27.9 3.2 3.5 1 1 1 2 2 2 1 Myb DNA-binding like SWI2_SNF2 PF18766.1 GAM28755.1 - 1.3e-25 90.4 1.4 1.3e-25 90.4 1.4 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase ResIII PF04851.15 GAM28755.1 - 1.7e-17 64.0 0.6 1.7e-17 64.0 0.6 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Med30 PF11315.8 GAM28755.1 - 0.13 12.4 0.1 0.13 12.4 0.1 3.4 2 2 1 3 3 3 0 Mediator complex subunit 30 Asp PF00026.23 GAM28756.1 - 4.8e-29 101.8 0.6 5.5e-28 98.3 0.6 2.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAM28756.1 - 3.2e-13 50.3 4.0 7.3e-13 49.1 4.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAM28756.1 - 2.3e-05 24.3 0.1 0.00017 21.4 0.0 2.3 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal SDA1 PF05285.12 GAM28757.1 - 2.9e-05 23.7 33.2 2.9e-05 23.7 33.2 4.7 3 1 1 4 4 4 2 SDA1 zf-RanBP PF00641.18 GAM28757.1 - 7.4e-05 22.0 5.0 7.4e-05 22.0 5.0 4.5 4 0 0 4 4 4 3 Zn-finger in Ran binding protein and others MgsA_C PF12002.8 GAM28762.1 - 0.15 12.0 0.0 0.43 10.5 0.0 1.6 2 0 0 2 2 2 0 MgsA AAA+ ATPase C terminal Hira PF07569.11 GAM28763.1 - 8.1e-48 163.1 0.1 8.1e-48 163.1 0.1 2.3 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 GAM28763.1 - 2.8e-31 107.1 23.1 7.3e-08 33.0 0.0 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM28763.1 - 1.1e-14 54.4 0.1 0.015 15.6 0.1 6.2 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 GAM28763.1 - 4.4e-06 26.3 0.2 8.2e-06 25.4 0.2 1.4 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region PD40 PF07676.12 GAM28763.1 - 0.0039 17.1 1.5 8.8 6.4 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 GAM28763.1 - 0.0043 16.4 0.0 6 6.1 0.0 3.8 4 0 0 4 4 4 1 WD40-like domain RR_TM4-6 PF06459.12 GAM28763.1 - 0.92 9.3 5.8 1.5 8.6 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Kelch_4 PF13418.6 GAM28764.1 - 5.4e-49 164.0 11.1 1.3e-09 37.9 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 GAM28764.1 - 4.7e-40 135.2 15.3 1.6e-11 44.2 0.0 8.2 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.6 GAM28764.1 - 9.5e-38 127.6 5.0 7e-09 35.5 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAM28764.1 - 3.5e-35 119.1 11.0 2.4e-07 30.8 0.1 6.6 3 1 3 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAM28764.1 - 2.5e-30 103.3 10.7 2.6e-06 27.2 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 GAM28764.1 - 1.5e-28 98.1 2.8 2.4e-07 30.2 0.0 6.3 6 0 0 6 6 6 4 Kelch motif zf-C3HC4_3 PF13920.6 GAM28764.1 - 6.1e-12 45.2 10.3 1e-11 44.5 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAM28764.1 - 1.8e-05 24.5 9.7 3.1e-05 23.7 9.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 K-box PF01486.17 GAM28764.1 - 0.0029 17.7 11.5 0.0029 17.7 11.5 3.0 2 1 0 2 2 2 1 K-box region zf-RING_5 PF14634.6 GAM28764.1 - 0.021 14.8 10.0 0.038 13.9 10.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF2039 PF10217.9 GAM28764.1 - 0.024 14.9 2.8 0.084 13.2 2.8 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) CLZ PF16526.5 GAM28764.1 - 0.17 12.3 13.8 0.45 10.9 8.3 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3328 PF11807.8 GAM28764.1 - 0.28 10.9 6.0 0.053 13.3 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Hamartin PF04388.12 GAM28764.1 - 4.7 5.7 32.3 6.7 5.2 32.3 1.1 1 0 0 1 1 1 0 Hamartin protein TIG PF01833.24 GAM28765.1 - 4.4e-08 33.1 47.3 6.2e-06 26.2 2.2 8.1 6 2 1 7 7 7 4 IPT/TIG domain EGF_2 PF07974.13 GAM28765.1 - 0.097 13.1 9.5 0.19 12.2 9.5 1.5 1 0 0 1 1 1 0 EGF-like domain ABC_membrane PF00664.23 GAM28766.1 - 9.4e-69 232.1 39.9 2.9e-44 151.8 17.6 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM28766.1 - 1.6e-52 177.7 1.8 8.5e-28 97.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter MMR_HSR1 PF01926.23 GAM28766.1 - 7.7e-09 35.6 0.8 0.0022 18.1 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAM28766.1 - 9.7e-09 35.3 1.6 9.3e-06 25.6 0.3 2.9 2 1 0 2 2 2 2 RsgA GTPase MTABC_N PF16185.5 GAM28766.1 - 5.9e-08 32.5 9.1 2.3e-07 30.6 9.1 2.0 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region SMC_N PF02463.19 GAM28766.1 - 1.2e-07 31.4 8.3 0.022 14.2 0.3 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAM28766.1 - 5.3e-06 26.1 0.4 0.041 13.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 GAM28766.1 - 5.7e-06 27.0 1.4 0.41 11.1 0.1 3.3 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 GAM28766.1 - 8.9e-06 25.9 3.4 0.0005 20.2 0.1 3.1 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 GAM28766.1 - 4.6e-05 23.9 0.0 0.19 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 GAM28766.1 - 0.00029 20.4 0.2 0.25 10.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAM28766.1 - 0.0015 17.9 0.2 0.27 10.5 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 GAM28766.1 - 0.0042 17.4 1.0 1.4 9.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 GAM28766.1 - 0.0081 16.4 0.2 5.3 7.3 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 GAM28766.1 - 0.0084 16.0 1.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FKBP_N_2 PF18023.1 GAM28766.1 - 0.0099 16.0 0.2 0.025 14.7 0.2 1.6 1 0 0 1 1 1 1 BDBT FKBP like N-terminal DUF815 PF05673.13 GAM28766.1 - 0.011 15.0 0.3 2.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 GAM28766.1 - 0.011 16.1 0.0 11 6.5 0.0 3.4 3 0 0 3 3 3 0 RNA helicase MeaB PF03308.16 GAM28766.1 - 0.013 14.5 0.8 3.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 GAM28766.1 - 0.027 14.2 0.0 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 GAM28766.1 - 0.044 13.9 5.6 0.69 10.0 0.1 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_30 PF13604.6 GAM28766.1 - 0.045 13.5 0.8 9.3 5.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAM28766.1 - 0.048 12.8 0.4 10 5.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 GAM28766.1 - 0.049 13.6 0.1 6 6.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 GAM28766.1 - 0.092 12.5 0.1 10 5.8 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 GAM28766.1 - 0.094 12.6 0.5 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Septin PF00735.18 GAM28766.1 - 0.1 11.9 0.1 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Septin IIGP PF05049.13 GAM28766.1 - 0.11 11.5 2.5 1.3 8.0 0.5 2.5 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 GAM28766.1 - 0.13 11.5 0.4 6 6.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 GAM28766.1 - 0.17 11.5 1.0 0.9 9.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 GAM28766.1 - 0.18 11.5 1.1 5.4 6.8 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 GAM28766.1 - 0.19 11.1 1.8 1.6 8.0 0.2 2.5 2 0 0 2 2 2 0 AIG1 family ABC_ATPase PF09818.9 GAM28766.1 - 0.41 9.4 2.8 33 3.1 0.1 3.4 3 1 0 3 3 3 0 Predicted ATPase of the ABC class FGGY_N PF00370.21 GAM28767.1 - 6.4e-50 170.0 0.0 8.7e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAM28767.1 - 9.8e-27 94.0 0.7 1.4e-26 93.5 0.7 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RabGAP-TBC PF00566.18 GAM28770.1 - 4.9e-54 183.2 5.0 7.9e-54 182.6 5.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 GAM28770.1 - 1.8e-46 156.6 9.7 9.9e-13 48.5 0.2 5.4 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28770.1 - 5.4e-29 100.2 8.9 8e-07 29.5 0.2 7.3 3 2 6 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM28770.1 - 9.2e-27 92.3 11.3 0.0004 20.7 0.0 9.1 8 1 1 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 GAM28770.1 - 1.2e-25 86.7 3.1 0.061 13.9 0.0 9.5 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 GAM28770.1 - 1.4e-17 63.5 4.0 0.00016 21.9 0.0 6.4 2 1 5 7 7 7 6 Ankyrin repeats (many copies) LANC_like PF05147.13 GAM28770.1 - 0.023 13.3 0.0 0.039 12.5 0.0 1.3 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein COX6B PF02297.17 GAM28770.1 - 2.1 8.7 5.2 26 5.1 0.2 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb DUF1965 PF09248.10 GAM28772.1 - 0.025 14.3 2.2 0.04 13.7 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) AAA_18 PF13238.6 GAM28773.1 - 1.2e-29 103.4 0.0 2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAM28773.1 - 2.7e-05 24.5 0.0 6.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAM28773.1 - 2.8e-05 24.6 0.2 0.00014 22.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain dNK PF01712.19 GAM28773.1 - 6.2e-05 22.9 1.4 0.0095 15.8 0.7 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_33 PF13671.6 GAM28773.1 - 8.7e-05 22.7 0.3 0.032 14.4 0.2 2.2 1 1 0 2 2 2 1 AAA domain ResIII PF04851.15 GAM28773.1 - 0.001 19.1 0.0 0.003 17.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 GAM28773.1 - 0.005 16.6 0.1 0.025 14.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAM28773.1 - 0.0057 17.0 0.0 0.0086 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GAM28773.1 - 0.0068 16.8 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 GAM28773.1 - 0.0084 16.2 0.2 0.076 13.1 0.2 2.1 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.6 GAM28773.1 - 0.0089 16.3 0.0 0.017 15.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain Thymidylate_kin PF02223.17 GAM28773.1 - 0.013 15.2 1.6 0.035 13.8 0.2 1.9 2 0 0 2 2 2 0 Thymidylate kinase Rad17 PF03215.15 GAM28773.1 - 0.019 14.9 0.5 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 GAM28773.1 - 0.02 15.3 0.2 0.068 13.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase CoaE PF01121.20 GAM28773.1 - 0.021 14.5 0.9 2.5 7.8 0.0 2.5 1 1 0 2 2 2 0 Dephospho-CoA kinase Ploopntkinase3 PF18751.1 GAM28773.1 - 0.029 14.3 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATPase PF06745.13 GAM28773.1 - 0.031 13.6 0.3 0.06 12.7 0.0 1.6 2 0 0 2 2 2 0 KaiC AAA_5 PF07728.14 GAM28773.1 - 0.031 14.3 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAM28773.1 - 0.038 13.7 0.0 0.084 12.6 0.0 1.7 2 1 0 2 2 2 0 IstB-like ATP binding protein KTI12 PF08433.10 GAM28773.1 - 0.049 13.1 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ADK PF00406.22 GAM28773.1 - 0.064 13.4 0.5 3.6 7.7 0.0 2.6 2 1 0 2 2 2 0 Adenylate kinase NTPase_1 PF03266.15 GAM28773.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NTPase Hydin_ADK PF17213.3 GAM28773.1 - 0.081 13.2 0.4 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_19 PF13245.6 GAM28773.1 - 0.1 12.9 0.6 0.19 12.0 0.5 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAM28773.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 GAM28773.1 - 0.18 11.1 0.2 0.52 9.6 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 GAM28773.1 - 0.24 11.1 0.8 0.67 9.6 0.6 1.7 1 1 1 2 2 2 0 AAA domain Alk_phosphatase PF00245.20 GAM28774.1 - 1e-83 281.6 6.6 1.7e-83 280.9 6.6 1.4 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 GAM28774.1 - 1.1e-05 24.9 1.8 4.3e-05 23.0 2.5 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily 4F5 PF04419.14 GAM28775.1 - 6.2e-05 23.8 9.2 8.8e-05 23.3 9.2 1.3 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.7 GAM28775.1 - 0.0074 16.6 1.7 0.012 16.0 1.7 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 GAM28775.1 - 0.022 15.0 1.0 0.03 14.6 1.0 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.7 GAM28775.1 - 0.051 13.7 3.3 0.15 12.2 3.3 1.8 1 1 0 1 1 1 0 Zinc-binding ATE_C PF04377.15 GAM28776.1 - 2.9e-48 163.9 1.7 2.9e-48 163.9 1.7 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 GAM28776.1 - 3.3e-22 78.7 0.7 9.5e-22 77.2 0.7 1.9 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Fer2_4 PF13510.6 GAM28777.1 - 0.14 12.3 4.4 0.71 10.0 0.2 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain TMEMspv1-c74-12 PF11044.8 GAM28777.1 - 1.7 8.7 3.9 3.3 7.8 3.9 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Dickkopf_N PF04706.12 GAM28777.1 - 3.4 8.2 21.2 0.19 12.2 2.3 3.5 3 1 1 4 4 3 0 Dickkopf N-terminal cysteine-rich region SGL PF08450.12 GAM28778.1 - 1.2e-66 224.8 0.2 1.6e-66 224.4 0.2 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 GAM28778.1 - 0.0083 16.2 1.8 8.9 6.9 0.0 3.9 4 0 0 4 4 4 2 Two component regulator propeller PQQ_2 PF13360.6 GAM28778.1 - 0.025 14.2 0.1 1.2 8.6 0.2 2.2 1 1 1 2 2 2 0 PQQ-like domain Lactonase PF10282.9 GAM28778.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Peptidase_S9_N PF02897.15 GAM28778.1 - 0.1 11.3 0.0 0.23 10.2 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain RCC1 PF00415.18 GAM28779.1 - 2.7e-66 220.0 8.7 1.4e-12 48.0 0.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM28779.1 - 5.8e-39 131.1 23.0 1.2e-11 44.1 0.2 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 GAM28779.1 - 5.6e-20 71.6 5.4 1.5e-15 57.4 2.4 2.4 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 GAM28779.1 - 0.021 14.9 0.7 0.15 12.2 0.0 2.6 2 1 1 3 3 3 0 BTB And C-terminal Kelch EF-hand_2 PF09068.11 GAM28779.1 - 0.11 12.7 0.2 0.25 11.5 0.2 1.7 1 1 0 1 1 1 0 EF hand V-SNARE PF05008.15 GAM28781.1 - 3.1e-13 49.9 3.7 3.1e-13 49.9 3.7 2.3 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 GAM28781.1 - 2.4e-12 46.9 3.4 2.4e-12 46.9 3.4 3.1 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAM28781.1 - 5e-05 23.1 0.3 5e-05 23.1 0.3 2.4 3 1 0 3 3 2 1 Sec20 DUF1542 PF07564.11 GAM28781.1 - 0.00045 20.3 3.7 0.00045 20.3 3.7 2.3 2 1 1 3 3 3 1 Domain of Unknown Function (DUF1542) Fusion_gly PF00523.18 GAM28781.1 - 0.0032 15.8 0.5 0.0032 15.8 0.5 1.8 2 0 0 2 2 2 1 Fusion glycoprotein F0 Arm-DNA-bind_2 PF12167.8 GAM28781.1 - 0.0052 16.7 0.1 0.015 15.2 0.1 1.8 1 0 0 1 1 1 1 Arm DNA-binding domain CALCOCO1 PF07888.11 GAM28781.1 - 0.0094 14.9 5.3 0.013 14.4 5.3 1.3 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1963 PF09234.10 GAM28781.1 - 0.01 16.3 1.9 0.012 16.1 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) Golgin_A5 PF09787.9 GAM28781.1 - 0.025 14.1 10.7 0.074 12.5 6.6 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Spectrin PF00435.21 GAM28781.1 - 0.085 13.4 5.4 2.6 8.6 2.9 3.1 2 1 0 3 3 3 0 Spectrin repeat Synaptobrevin PF00957.21 GAM28781.1 - 0.12 12.2 0.3 0.12 12.2 0.3 2.4 2 1 0 2 2 2 0 Synaptobrevin Pex24p PF06398.11 GAM28781.1 - 0.17 10.9 0.1 0.17 10.9 0.1 2.0 1 1 0 2 2 2 0 Integral peroxisomal membrane peroxin DASH_Duo1 PF08651.10 GAM28781.1 - 0.2 11.4 6.7 7.4 6.4 0.1 3.6 3 1 1 4 4 4 0 DASH complex subunit Duo1 PilJ PF13675.6 GAM28781.1 - 0.26 11.3 7.0 4.5 7.3 2.0 2.5 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Laminin_II PF06009.12 GAM28781.1 - 0.29 11.1 8.7 1.9 8.5 0.1 2.7 2 1 1 3 3 3 0 Laminin Domain II Syntaxin_2 PF14523.6 GAM28781.1 - 0.41 11.0 12.7 2.9 8.3 7.5 3.2 2 1 1 3 3 3 0 Syntaxin-like protein Sec8_exocyst PF04048.14 GAM28781.1 - 0.43 10.5 6.5 7.5 6.4 0.1 2.8 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain COG2 PF06148.11 GAM28781.1 - 0.61 10.2 6.1 3.7 7.6 0.1 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cnn_1N PF07989.11 GAM28781.1 - 0.76 10.0 5.1 0.38 11.0 2.2 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Phage_pRha PF09669.10 GAM28781.1 - 0.88 10.2 5.8 1.8e+02 2.8 5.8 2.6 1 1 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) Prominin PF05478.11 GAM28781.1 - 1.8 6.4 8.8 5.1 4.9 5.6 2.1 2 0 0 2 2 2 0 Prominin LRRC37AB_C PF14914.6 GAM28781.1 - 2.2 8.2 9.7 0.63 9.9 0.2 2.7 2 1 1 3 3 3 0 LRRC37A/B like protein 1 C-terminal domain DUF745 PF05335.13 GAM28781.1 - 2.7 7.7 8.0 6.4 6.4 4.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) E1-E2_ATPase PF00122.20 GAM28782.1 - 3.7e-37 127.6 4.2 3.7e-37 127.6 4.2 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAM28782.1 - 9.9e-24 84.0 8.4 9.9e-24 84.0 8.4 3.9 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAM28782.1 - 2.2e-23 83.7 0.1 1.1e-10 42.2 0.0 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAM28782.1 - 8.6e-17 61.0 0.0 1.8e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAM28782.1 - 6.1e-10 38.6 0.0 1.9e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAM28782.1 - 0.00027 20.8 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAM28782.1 - 0.0085 16.5 0.0 0.24 11.8 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT-C2 PF10358.9 GAM28784.1 - 1e-25 90.2 4.4 1e-25 90.2 4.4 2.2 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.19 GAM28784.1 - 1e-19 70.7 0.8 4.3e-19 68.7 0.1 2.6 2 0 0 2 2 2 1 DIL domain ACDC PF14733.6 GAM28784.1 - 0.00034 20.9 0.7 0.0017 18.6 0.2 2.5 2 0 0 2 2 2 1 AP2-coincident C-terminal KELK PF15796.5 GAM28784.1 - 0.002 18.5 13.6 0.002 18.5 13.6 7.2 5 2 1 6 6 6 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 GAM28784.1 - 0.0026 18.3 22.9 0.0026 18.3 22.9 5.5 1 1 2 4 4 4 1 Fez1 ADIP PF11559.8 GAM28784.1 - 0.015 15.4 0.8 0.015 15.4 0.8 6.9 4 2 2 6 6 6 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 GAM28784.1 - 0.025 15.2 49.5 0.08 13.6 0.1 8.3 8 2 1 9 9 9 0 SlyX Fib_alpha PF08702.10 GAM28784.1 - 0.03 14.5 0.9 0.03 14.5 0.9 6.7 7 1 1 8 8 8 0 Fibrinogen alpha/beta chain family SAT PF16073.5 GAM28784.1 - 1.4 8.6 9.4 0.77 9.4 1.0 3.4 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Erf4 PF10256.9 GAM28784.1 - 1.7 8.8 7.2 4.1 7.5 0.1 4.6 4 2 1 5 5 5 0 Golgin subfamily A member 7/ERF4 family DAD PF02109.16 GAM28785.1 - 1.3e-41 141.3 6.6 1.4e-41 141.2 6.6 1.0 1 0 0 1 1 1 1 DAD family Ald_Xan_dh_C2 PF02738.18 GAM28786.1 - 6.3e-204 678.5 0.0 8.7e-204 678.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 GAM28786.1 - 4e-46 156.9 0.0 7.4e-46 156.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 GAM28786.1 - 2.2e-31 108.1 0.0 4.6e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 GAM28786.1 - 2.8e-30 104.1 0.1 6.1e-30 103.1 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 GAM28786.1 - 1.3e-29 102.7 0.3 2.9e-29 101.6 0.3 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 GAM28786.1 - 3.3e-09 36.6 1.0 1e-08 35.0 0.1 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 GAM28786.1 - 0.43 10.4 3.6 2 8.3 3.6 2.2 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Formyl_trans_N PF00551.19 GAM28788.1 - 0.025 14.3 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Formyl transferase DUF3644 PF12358.8 GAM28790.1 - 0.23 12.0 1.4 0.4 11.2 0.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3644) DUF1803 PF08820.10 GAM28793.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) DDE_Tnp_4 PF13359.6 GAM28798.1 - 4e-07 29.8 0.9 5.3e-06 26.2 0.1 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM28798.1 - 0.035 13.8 0.1 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 Transposase DDE domain FNIP PF05725.12 GAM28799.1 - 1.4e-12 47.6 0.5 2.5e-07 30.8 0.0 4.0 3 1 1 4 4 4 3 FNIP Repeat HA2 PF04408.23 GAM28799.1 - 0.061 13.6 0.0 0.095 13.0 0.0 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) FNIP PF05725.12 GAM28800.1 - 6.9e-39 131.8 3.7 5.6e-12 45.6 0.2 4.2 3 1 1 4 4 4 4 FNIP Repeat HSP33 PF01430.19 GAM28801.1 - 1.5e-39 136.1 0.0 1.7e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein PLDc_2 PF13091.6 GAM28802.1 - 1.1e-18 67.4 0.0 1e-09 38.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAM28802.1 - 3.4e-08 33.3 0.2 0.00064 19.8 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif AAA PF00004.29 GAM28803.1 - 3.3e-41 140.8 0.0 6.1e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM28803.1 - 1.7e-10 40.5 0.1 3.8e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAM28803.1 - 3.1e-05 24.0 0.0 0.00011 22.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM28803.1 - 0.00029 21.1 0.0 0.024 14.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 GAM28803.1 - 0.00058 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 GAM28803.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 GAM28803.1 - 0.0014 19.0 0.1 0.017 15.5 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 GAM28803.1 - 0.0038 17.6 0.0 0.0089 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 GAM28803.1 - 0.004 17.3 0.0 0.0075 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAM28803.1 - 0.0049 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 GAM28803.1 - 0.017 14.6 0.0 0.045 13.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAM28803.1 - 0.021 14.2 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAM28803.1 - 0.033 14.4 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 GAM28803.1 - 0.035 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 GAM28803.1 - 0.049 13.4 0.2 0.27 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 GAM28803.1 - 0.049 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAM28803.1 - 0.086 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 GAM28803.1 - 0.12 12.2 0.0 11 5.8 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 GAM28803.1 - 0.2 11.4 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RhoGEF PF00621.20 GAM28804.1 - 7.5e-40 137.1 1.6 1.2e-39 136.5 1.6 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF4108 PF13390.6 GAM28804.1 - 0.033 14.1 0.1 0.092 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) Rap_GAP PF02145.15 GAM28805.1 - 6.5e-63 211.6 0.2 1.5e-62 210.5 0.2 1.7 1 0 0 1 1 1 1 Rap/ran-GAP MFS_1 PF07690.16 GAM28807.1 - 1.9e-32 112.6 29.7 2.4e-26 92.5 6.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM28807.1 - 1.4e-14 53.8 3.9 1.4e-14 53.8 3.9 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter Pyrophosphatase PF00719.19 GAM28808.1 - 2.7e-47 160.6 1.9 3.3e-47 160.2 1.9 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase PP2C PF00481.21 GAM28809.1 - 4.9e-46 157.5 0.3 3.7e-32 112.0 0.0 2.6 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAM28809.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C DUF4370 PF14290.6 GAM28809.1 - 0.034 14.0 0.5 12 5.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4370) Macoilin PF09726.9 GAM28810.1 - 0.86 8.1 12.5 1.1 7.7 12.5 1.1 1 0 0 1 1 1 0 Macoilin family ANAPC1 PF12859.7 GAM28810.1 - 5 7.7 14.7 12 6.5 14.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 RPM2 PF08579.11 GAM28811.1 - 0.043 14.2 0.8 0.094 13.1 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) CAP_GLY PF01302.25 GAM28812.1 - 2.3e-16 59.6 0.4 3.9e-16 58.8 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 GAM28812.1 - 5.4e-12 45.7 41.4 0.00013 22.3 1.3 6.2 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM28812.1 - 1.6e-07 30.9 42.0 0.00095 18.9 1.9 6.6 4 2 2 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 GAM28812.1 - 0.0025 17.4 14.3 0.012 15.1 0.1 4.1 3 1 0 4 4 4 2 Leucine-rich repeat YajC PF02699.15 GAM28812.1 - 0.06 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit LRR_6 PF13516.6 GAM28812.1 - 1.3 9.3 28.8 1.8 8.8 0.9 7.2 7 0 0 7 7 7 0 Leucine Rich repeat LIM PF00412.22 GAM28813.1 - 1.5e-34 118.0 45.2 5.2e-12 45.8 5.9 5.2 5 0 0 5 5 5 5 LIM domain Rap_GAP PF02145.15 GAM28814.1 - 1.1e-49 168.5 0.1 3e-49 167.1 0.1 1.7 1 0 0 1 1 1 1 Rap/ran-GAP Sporozoite_P67 PF05642.11 GAM28814.1 - 0.016 13.3 1.0 0.025 12.7 1.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Arm PF00514.23 GAM28814.1 - 0.027 14.5 0.1 0.089 12.9 0.1 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Abhydrolase_1 PF00561.20 GAM28815.1 - 1.3e-20 74.1 0.0 2.1e-20 73.4 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAM28815.1 - 1.4e-15 58.6 0.0 1.8e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAM28815.1 - 6.9e-11 41.9 0.0 9.7e-11 41.4 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 GAM28815.1 - 0.016 14.5 0.0 0.037 13.3 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 GAM28815.1 - 0.032 12.9 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family Abhydrolase_5 PF12695.7 GAM28815.1 - 0.048 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.12 GAM28815.1 - 0.049 13.6 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Esterase PF00756.20 GAM28815.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Tetraspanin PF00335.20 GAM28816.1 - 3.5e-27 95.6 15.2 4.2e-27 95.3 15.2 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF4131 PF13567.6 GAM28816.1 - 0.079 12.6 7.0 0.54 9.9 4.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) EMP70 PF02990.16 GAM28816.1 - 0.42 9.2 6.4 0.59 8.7 6.4 1.4 1 1 0 1 1 1 0 Endomembrane protein 70 MARVEL PF01284.23 GAM28816.1 - 2.1 8.4 19.1 2.1 8.4 10.4 2.2 1 1 1 2 2 2 0 Membrane-associating domain DUF4342 PF14242.6 GAM28816.1 - 4.1 7.5 11.3 0.63 10.1 3.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4342) Ribosomal_L44 PF00935.19 GAM28817.1 - 3e-32 110.9 12.7 6.1e-32 109.9 12.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 SH3_2 PF07653.17 GAM28818.1 - 3.2e-14 52.3 0.1 5.3e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAM28818.1 - 2.1e-11 43.5 0.1 3e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAM28818.1 - 8.8e-11 41.3 0.2 1.3e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 SH3 domain zinc_ribbon_2 PF13240.6 GAM28818.1 - 0.001 18.7 3.6 0.0017 18.0 3.6 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 GAM28818.1 - 0.0059 16.6 1.7 0.01 15.8 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_3 PF13920.6 GAM28818.1 - 0.022 14.6 1.8 0.034 14.0 1.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CTP_transf_like PF01467.26 GAM28819.1 - 8.1e-44 149.3 0.0 3.2e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 GAM28819.1 - 1e-05 25.5 3.2 1.1 9.2 0.3 3.6 3 1 0 3 3 3 3 FAD synthetase Lactamase_B_3 PF13483.6 GAM28819.1 - 0.035 14.0 0.1 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase superfamily domain U3_assoc_6 PF08640.11 GAM28819.1 - 0.095 12.8 1.4 0.19 11.8 1.4 1.4 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 adh_short PF00106.25 GAM28820.1 - 1e-38 132.7 0.0 1.3e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM28820.1 - 1.3e-19 70.7 0.0 1.8e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM28820.1 - 1.3e-10 41.5 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Luteo_PO PF04662.13 GAM28820.1 - 0.073 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Luteovirus P0 protein GIDA PF01134.22 GAM28821.1 - 1.5e-153 511.5 0.1 2.1e-153 511.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 GAM28821.1 - 9.6e-67 225.2 0.2 1.7e-66 224.4 0.2 1.4 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 GAM28821.1 - 4.6e-07 29.5 0.8 4.6e-07 29.5 0.8 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAM28821.1 - 6.6e-05 22.3 5.1 0.00036 19.8 5.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAM28821.1 - 0.0012 18.0 6.9 0.0031 16.7 3.3 2.2 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAM28821.1 - 0.032 13.5 5.4 0.039 13.2 1.7 2.5 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAM28821.1 - 0.077 11.7 5.1 0.33 9.6 1.5 3.0 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 GAM28821.1 - 0.13 11.1 4.6 5.5 5.7 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 GAM28821.1 - 0.16 12.6 0.6 0.39 11.3 0.6 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAM28821.1 - 0.55 9.4 3.2 7.8 5.7 3.2 2.4 1 1 0 1 1 1 0 Thi4 family FNIP PF05725.12 GAM28822.1 - 6.1e-67 221.6 4.0 6.9e-10 38.9 0.0 8.5 6 1 4 10 10 10 10 FNIP Repeat LRR_5 PF13306.6 GAM28822.1 - 4.3e-08 33.2 0.0 0.18 11.8 0.0 4.1 1 1 3 4 4 4 3 BspA type Leucine rich repeat region (6 copies) TFIIA_gamma_N PF02268.16 GAM28822.1 - 0.00013 22.0 1.9 21 5.2 0.0 6.0 4 2 2 7 7 7 1 Transcription initiation factor IIA, gamma subunit, helical domain PyocinActivator PF11112.8 GAM28822.1 - 0.031 14.4 0.0 1e+02 3.1 0.0 4.8 5 1 1 6 6 6 0 Pyocin activator protein PrtN Podoplanin PF05808.11 GAM28823.1 - 6.7e-06 26.3 0.1 6.7e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 Podoplanin Y_Y_Y PF07495.13 GAM28823.1 - 0.047 13.6 4.9 0.2 11.6 0.0 4.2 5 0 0 5 5 5 0 Y_Y_Y domain DUF2012 PF09430.10 GAM28823.1 - 0.12 12.4 2.6 3.6 7.7 0.0 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2012) DUF5114 PF17141.4 GAM28823.1 - 0.96 10.0 8.2 0.11 13.0 0.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5114) PH PF00169.29 GAM28824.1 - 4.3e-22 78.6 0.9 8.6e-22 77.6 0.9 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM28824.1 - 8.6e-09 35.8 4.9 5.2e-08 33.3 4.9 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 GAM28824.1 - 5.7e-05 23.2 0.6 0.00011 22.3 0.6 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 GAM28824.1 - 0.00019 21.6 0.6 0.0005 20.3 0.6 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 GAM28824.1 - 0.0045 17.3 0.2 0.011 16.1 0.2 1.6 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PH_9 PF15410.6 GAM28824.1 - 0.0053 17.1 1.3 0.13 12.7 1.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 GAM28824.1 - 0.093 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain BNIP3 PF06553.12 GAM28824.1 - 0.16 11.7 1.9 0.26 10.9 1.9 1.3 1 0 0 1 1 1 0 BNIP3 FNIP PF05725.12 GAM28825.1 - 3.8e-63 209.4 6.7 1.1e-09 38.3 0.0 7.7 4 2 4 8 8 8 8 FNIP Repeat LRR_5 PF13306.6 GAM28825.1 - 2.5e-07 30.7 0.0 0.093 12.7 0.0 3.5 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) F-box PF00646.33 GAM28825.1 - 0.012 15.5 1.7 0.031 14.2 1.7 1.7 1 0 0 1 1 1 0 F-box domain ParBc_2 PF08857.11 GAM28825.1 - 0.15 12.1 1.0 21 5.2 0.1 4.0 1 1 5 6 6 6 0 Putative ParB-like nuclease Pox_Ag35 PF03286.14 GAM28826.1 - 0.11 12.2 17.5 0.21 11.4 17.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2985 PF11204.8 GAM28826.1 - 0.22 11.7 0.1 0.22 11.7 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2985) Cwf_Cwc_15 PF04889.12 GAM28826.1 - 3.2 7.4 17.7 4.9 6.8 17.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CCDC53 PF10152.9 GAM28826.1 - 5.8 7.3 11.1 12 6.2 11.1 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RabGAP-TBC PF00566.18 GAM28827.1 - 8.8e-53 179.1 0.4 1.3e-52 178.6 0.1 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain F-box-like PF12937.7 GAM28827.1 - 0.012 15.5 0.8 0.06 13.3 0.2 2.5 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 GAM28827.1 - 0.03 14.2 0.9 0.088 12.7 0.5 2.0 2 0 0 2 2 2 0 F-box domain DUF4715 PF15835.5 GAM28827.1 - 0.15 12.1 0.0 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) Pkinase PF00069.25 GAM28828.1 - 3.9e-70 236.2 0.0 5.6e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28828.1 - 2.7e-35 121.9 0.0 3.7e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 GAM28828.1 - 1.3e-19 70.6 1.1 2.3e-19 69.8 0.4 1.8 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 GAM28828.1 - 9.7e-08 32.1 0.6 2.4e-07 30.8 0.6 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM28828.1 - 4.5e-06 27.0 1.7 0.00013 22.4 1.7 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 GAM28828.1 - 2.3e-05 24.8 1.6 0.0002 21.7 0.4 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 GAM28828.1 - 2.7e-05 24.4 1.2 4.3e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain Pkinase_C PF00433.24 GAM28828.1 - 2.9e-05 24.7 0.3 7e-05 23.5 0.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 GAM28828.1 - 0.006 15.9 0.2 1.1 8.4 0.0 2.6 3 0 0 3 3 3 2 Kinase-like PH_6 PF15406.6 GAM28828.1 - 0.0085 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain FTA2 PF13095.6 GAM28828.1 - 0.01 15.5 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 GAM28828.1 - 0.014 14.4 0.1 0.025 13.5 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain PH_13 PF16652.5 GAM28828.1 - 0.026 14.4 0.1 0.058 13.2 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Ribosomal_S10 PF00338.22 GAM28828.1 - 0.076 13.3 0.1 18 5.6 0.1 2.4 1 1 1 2 2 2 0 Ribosomal protein S10p/S20e ANTH PF07651.16 GAM28829.1 - 3.4e-50 170.6 0.9 3.4e-50 170.6 0.9 2.4 3 0 0 3 3 3 1 ANTH domain ENTH PF01417.20 GAM28829.1 - 5.6e-07 29.6 0.0 1.7e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 ENTH domain RWP-RK PF02042.15 GAM28829.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 RWP-RK domain Cupin_8 PF13621.6 GAM28830.1 - 1.2e-29 103.8 0.2 2.5e-29 102.8 0.2 1.5 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 GAM28830.1 - 1.2e-05 25.7 0.4 9.5e-05 22.8 0.1 2.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 GAM28830.1 - 0.0016 18.1 0.3 0.0025 17.4 0.3 1.4 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 GAM28830.1 - 0.097 12.4 0.1 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 Cupin domain RRM_1 PF00076.22 GAM28831.1 - 8.5e-25 86.4 4.8 6.6e-09 35.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAM28831.1 - 0.11 12.5 0.5 0.96 9.5 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MMM1 PF10296.9 GAM28832.1 - 3.7e-08 32.8 0.2 3.6e-07 29.5 0.1 1.9 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Sec7 PF01369.20 GAM28834.1 - 7.6e-54 182.2 1.7 7.6e-54 182.2 1.7 1.8 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 GAM28834.1 - 2e-18 66.8 0.6 5e-18 65.5 0.6 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM28834.1 - 1.8e-05 25.1 0.5 1.8e-05 25.1 0.5 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PUCC PF03209.15 GAM28834.1 - 0.00052 19.1 2.2 0.00079 18.5 2.2 1.2 1 0 0 1 1 1 1 PUCC protein PH_8 PF15409.6 GAM28834.1 - 0.009 16.3 0.4 0.43 10.9 0.4 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain LapA_dom PF06305.11 GAM28834.1 - 0.14 11.9 6.8 2.1 8.2 0.0 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SMYLE_N PF18615.1 GAM28834.1 - 2.9 7.4 5.8 2.5 7.6 4.2 1.6 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain UQ_con PF00179.26 GAM28835.1 - 6e-43 145.9 0.1 9.9e-43 145.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 GAM28835.1 - 3.3e-11 43.8 0.0 7.2e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Rad60-SLD PF11976.8 GAM28835.1 - 3.9e-06 26.6 0.9 9.2e-06 25.4 0.7 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Prok-E2_B PF14461.6 GAM28835.1 - 7.6e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B VWA PF00092.28 GAM28835.1 - 4.9e-05 23.7 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain ubiquitin PF00240.23 GAM28835.1 - 9.2e-05 22.1 0.3 0.00018 21.2 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 GAM28835.1 - 0.035 14.3 0.2 15 5.9 0.0 2.6 2 0 0 2 2 2 0 TUG ubiquitin-like domain FNIP PF05725.12 GAM28836.1 - 2.3e-50 168.5 38.2 2.7e-12 46.6 5.0 8.3 6 2 3 9 9 9 8 FNIP Repeat RCDG1 PF15725.5 GAM28837.1 - 0.67 10.4 9.9 0.49 10.9 4.5 2.6 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein LIM PF00412.22 GAM28838.1 - 7.8e-31 106.1 36.2 9.7e-12 44.9 9.2 3.1 3 0 0 3 3 3 3 LIM domain zf-C3HC4_3 PF13920.6 GAM28838.1 - 0.0028 17.5 34.1 0.13 12.2 1.8 4.9 3 3 2 5 5 5 4 Zinc finger, C3HC4 type (RING finger) IF-2B PF01008.17 GAM28840.1 - 9.5e-65 218.6 0.0 1.1e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Tyr_Deacylase PF02580.16 GAM28841.1 - 3.3e-39 134.7 0.0 3.7e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase PKD_channel PF08016.12 GAM28842.1 - 8.2e-11 41.2 4.4 8.2e-11 41.2 4.4 1.7 2 0 0 2 2 2 1 Polycystin cation channel Corazonin PF17308.2 GAM28842.1 - 0.2 12.0 6.8 0.42 11.0 6.8 1.5 1 0 0 1 1 1 0 Pro-corazonin DUF4681 PF15732.5 GAM28842.1 - 2.2 8.6 7.7 0.2 11.9 0.9 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4681) DUF1492 PF07374.11 GAM28842.1 - 4.7 7.4 6.8 2.7 8.2 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) XPG_N PF00752.17 GAM28843.1 - 3.1e-24 85.4 0.0 7.8e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 GAM28843.1 - 1.8e-20 73.1 0.2 1.8e-20 73.1 0.2 2.5 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 GAM28843.1 - 1.8e-06 27.6 0.1 1.8e-06 27.6 0.1 1.6 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.20 GAM28843.1 - 0.015 15.9 0.0 0.064 13.9 0.0 2.0 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.17 GAM28843.1 - 0.017 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 GAM28844.1 - 3.9e-41 141.5 0.4 4.2e-39 134.9 0.4 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAM28844.1 - 3.6e-31 108.0 0.0 7.6e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 GAM28844.1 - 1.3e-10 41.7 0.4 3.9e-10 40.2 0.4 1.9 1 0 0 1 1 1 1 PH domain PI3K_C2 PF00792.24 GAM28844.1 - 0.0013 18.7 0.0 0.0042 17.0 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 GAM28844.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) FNIP PF05725.12 GAM28845.1 - 1.7e-62 207.4 17.3 4.3e-10 39.6 0.1 6.6 6 0 0 6 6 6 6 FNIP Repeat ECH_1 PF00378.20 GAM28846.1 - 1.1e-48 165.7 0.7 1.7e-48 165.1 0.7 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAM28846.1 - 2.1e-23 83.3 0.2 2.5e-21 76.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF3867 PF12983.7 GAM28846.1 - 0.0011 19.1 0.3 0.0021 18.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3867) PTS_IIA PF02255.16 GAM28846.1 - 0.02 14.9 0.2 0.041 13.9 0.2 1.5 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit TA0956 PF11513.8 GAM28846.1 - 0.12 12.7 0.2 0.2 11.9 0.2 1.4 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 Methyltransf_16 PF10294.9 GAM28847.1 - 3.9e-16 59.3 0.0 5.1e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAM28847.1 - 5.9e-08 32.7 0.0 9.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM28847.1 - 0.012 16.3 0.0 0.031 14.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAM28847.1 - 0.025 15.3 0.0 0.17 12.6 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAM28847.1 - 0.032 15.0 0.0 0.073 13.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAM28847.1 - 0.08 12.5 0.0 0.31 10.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Lipoprotein_17 PF04200.12 GAM28847.1 - 0.22 11.9 0.2 0.22 11.9 0.2 2.1 2 0 0 2 2 2 0 Lipoprotein associated domain EF-hand_7 PF13499.6 GAM28848.1 - 0.091 13.2 0.3 0.2 12.1 0.3 1.5 1 0 0 1 1 1 0 EF-hand domain pair Rotavirus_VP1 PF12289.8 GAM28848.1 - 0.12 11.5 4.9 0.2 10.6 0.0 2.1 2 0 0 2 2 2 0 Rotavirus VP1 C-terminal domain SRP-alpha_N PF04086.13 GAM28848.1 - 2 8.2 14.0 3.7 7.4 14.0 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SapB_2 PF03489.17 GAM28849.1 - 2.8e-20 72.1 11.7 3.2e-10 39.9 0.8 3.7 4 0 0 4 4 4 2 Saposin-like type B, region 2 SapB_1 PF05184.15 GAM28849.1 - 6.7e-17 61.2 13.0 6.6e-09 35.6 2.1 3.1 3 0 0 3 3 3 2 Saposin-like type B, region 1 HypD PF01924.16 GAM28849.1 - 0.0058 15.8 2.2 0.53 9.3 0.1 2.1 1 1 0 2 2 2 2 Hydrogenase formation hypA family DUF5332 PF17266.2 GAM28849.1 - 0.024 14.3 8.4 0.46 10.2 0.2 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5332) YBD PF17725.1 GAM28849.1 - 0.026 14.4 0.4 3.5 7.4 0.1 2.2 2 0 0 2 2 2 0 YAP binding domain zf_C2H2_10 PF18414.1 GAM28849.1 - 0.19 11.3 1.8 4.9 6.8 0.4 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger DUF836 PF05768.14 GAM28849.1 - 0.44 11.0 3.8 9 6.8 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Zn-C2H2_12 PF18112.1 GAM28849.1 - 0.73 10.4 4.5 18 5.9 0.3 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain MACPF PF01823.19 GAM28850.1 - 9.8e-16 58.5 2.5 1.2e-15 58.2 2.5 1.1 1 0 0 1 1 1 1 MAC/Perforin domain FTHFS PF01268.19 GAM28850.1 - 0.00062 18.1 0.0 0.00091 17.5 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase RTT107_BRCT_5 PF16770.5 GAM28851.1 - 7.9e-13 48.2 0.0 2.1e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 GAM28851.1 - 1.8e-10 41.1 0.0 3.6e-06 27.3 0.1 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAM28851.1 - 1.4e-08 35.0 0.4 5.2e-07 29.9 0.4 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAM28851.1 - 0.00072 19.5 0.2 0.0018 18.2 0.2 1.7 1 0 0 1 1 1 1 twin BRCT domain CRAL_TRIO PF00650.20 GAM28852.1 - 8.8e-36 123.0 0.0 1.2e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM28852.1 - 2.9e-09 37.0 0.7 8.6e-09 35.5 0.7 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAM28852.1 - 2.2e-06 27.9 0.0 3.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain C2 PF00168.30 GAM28853.1 - 1.7e-26 92.5 0.3 2.4e-26 92.0 0.3 1.2 1 0 0 1 1 1 1 C2 domain Corona_nucleoca PF00937.18 GAM28854.1 - 0.38 9.7 11.8 0.56 9.2 11.5 1.4 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein PBP1_TM PF14812.6 GAM28854.1 - 1.9 8.9 18.2 4.7 7.6 10.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMEM210 PF15195.6 GAM28855.1 - 0.028 14.8 0.1 0.049 14.0 0.1 1.4 1 0 0 1 1 1 0 TMEM210 family DUF998 PF06197.13 GAM28855.1 - 0.14 11.7 2.3 1.3 8.6 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Tmemb_9 PF05434.11 GAM28855.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.1 1 1 1 2 2 2 0 TMEM9 DUF2975 PF11188.8 GAM28855.1 - 0.17 11.8 2.7 0.35 10.7 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Methyltransf_12 PF08242.12 GAM28856.1 - 0.11 13.2 1.4 0.53 11.1 1.4 2.1 1 0 0 1 1 1 0 Methyltransferase domain Amnionless PF14828.6 GAM28857.1 - 0.022 13.6 0.0 2.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Amnionless FNIP PF05725.12 GAM28858.1 - 9.4e-17 60.9 4.6 4e-05 23.7 0.0 5.8 5 1 1 6 6 6 5 FNIP Repeat F-box_5 PF18511.1 GAM28859.1 - 0.034 13.7 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 F-box TTL PF03133.15 GAM28860.1 - 2.6e-21 76.0 0.2 1.1e-12 47.8 0.1 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GAM28860.1 - 6.6e-08 32.1 0.0 1.4e-06 27.8 0.0 2.5 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 GAM28860.1 - 0.0027 17.0 0.0 0.0078 15.5 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp 5_nucleotid PF05761.14 GAM28861.1 - 7.6e-171 569.0 4.4 9e-171 568.8 4.4 1.1 1 0 0 1 1 1 1 5' nucleotidase family FR47 PF08445.10 GAM28864.1 - 2e-14 53.3 0.0 3.6e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 GAM28864.1 - 1.5e-05 25.2 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 GAM28864.1 - 8.3e-05 23.3 0.0 0.00014 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAM28864.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM28864.1 - 0.00091 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 GAM28864.1 - 0.0022 17.6 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Gly_acyl_tr_C PF08444.10 GAM28864.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Ank_4 PF13637.6 GAM28865.1 - 6.3e-06 26.6 0.5 0.6 10.7 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM28865.1 - 0.00024 21.6 0.4 0.00071 20.1 0.3 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM28865.1 - 0.003 17.9 0.5 6.3 7.7 0.1 3.9 3 1 1 4 4 4 1 Ankyrin repeat FeS_assembly_P PF01883.19 GAM28866.1 - 0.11 12.6 1.3 0.18 12.0 0.2 2.0 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein BUD22 PF09073.10 GAM28866.1 - 3.8 6.8 13.5 5.8 6.2 13.5 1.2 1 0 0 1 1 1 0 BUD22 PMSI1 PF15322.6 GAM28866.1 - 6.5 6.1 7.3 11 5.4 7.3 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative YqfQ PF14181.6 GAM28866.1 - 6.6 6.9 8.6 3.3 7.9 4.6 2.4 1 1 1 2 2 2 0 YqfQ-like protein DUF202 PF02656.15 GAM28868.1 - 4e-12 46.4 7.6 1e-11 45.1 5.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TctB PF07331.11 GAM28868.1 - 0.0034 17.7 0.1 0.0045 17.3 0.1 1.3 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DUF2207 PF09972.9 GAM28868.1 - 0.011 14.6 2.9 0.019 13.8 2.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC2_membrane_3 PF12698.7 GAM28868.1 - 0.22 10.6 6.1 0.11 11.6 3.2 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein Polysacc_synt_C PF14667.6 GAM28868.1 - 4.2 7.4 13.1 30 4.7 13.1 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Skp1 PF01466.19 GAM28869.1 - 4.4e-30 103.5 1.5 9e-30 102.6 1.5 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GAM28869.1 - 3.9e-28 97.4 0.2 1e-27 96.1 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF2594 PF10769.9 GAM28869.1 - 0.15 12.1 0.2 0.36 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2594) zf-C3HC4_3 PF13920.6 GAM28870.1 - 1.7e-08 34.2 15.5 1.7e-08 34.2 15.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAM28870.1 - 5.2e-08 32.6 17.9 5.2e-08 32.6 17.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM28870.1 - 5.5e-08 32.6 19.1 5.5e-08 32.6 19.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM28870.1 - 2.4e-05 24.2 17.4 2.4e-05 24.2 17.4 3.0 2 2 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAM28870.1 - 2.9e-05 24.3 18.4 2.9e-05 24.3 18.4 2.6 2 0 0 2 2 2 1 Ring finger domain U-box PF04564.15 GAM28870.1 - 0.00016 21.8 0.1 0.00043 20.4 0.1 1.8 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.6 GAM28870.1 - 0.00024 21.1 14.9 0.00024 21.1 14.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAM28870.1 - 0.0043 17.2 17.1 0.0043 17.2 17.1 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C2H2_assoc3 PF16637.5 GAM28870.1 - 1.6 9.0 6.2 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz zf-RING_6 PF14835.6 GAM28870.1 - 4.6 7.2 19.0 0.12 12.3 8.1 3.0 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Nucleopor_Nup85 PF07575.13 GAM28871.1 - 1.5e-61 208.6 24.2 1.9e-60 205.0 18.0 2.1 2 0 0 2 2 2 2 Nup85 Nucleoporin DUF1837 PF08878.11 GAM28871.1 - 0.036 13.9 0.4 0.12 12.2 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) DUF383 PF04063.14 GAM28871.1 - 0.043 13.5 1.2 0.48 10.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF383) S10_plectin PF03501.15 GAM28872.1 - 1.2e-37 127.8 0.1 1.5e-37 127.6 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Pex14_N PF04695.13 GAM28873.1 - 8.5e-30 104.5 5.4 8.5e-30 104.5 5.4 5.3 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5572 PF17733.1 GAM28873.1 - 6.2e-07 29.1 0.9 2.4e-06 27.3 0.9 2.1 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Baculo_PEP_C PF04513.12 GAM28873.1 - 0.069 13.2 3.0 0.18 11.9 3.0 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 GAM28873.1 - 0.79 10.0 2.7 11 6.3 0.6 2.9 2 0 0 2 2 2 0 Haemolysin XhlA RhoGEF PF00621.20 GAM28874.1 - 1.7e-37 129.4 0.7 4.1e-37 128.2 0.7 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAM28874.1 - 1.1e-08 35.5 0.5 2.8e-08 34.2 0.5 1.7 1 0 0 1 1 1 1 PH domain Arm PF00514.23 GAM28874.1 - 5.2e-08 32.7 18.8 0.002 18.1 0.1 6.9 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat IQ_SEC7_PH PF16453.5 GAM28874.1 - 2.9e-05 24.0 0.4 7.4e-05 22.7 0.4 1.6 1 0 0 1 1 1 1 PH domain HEAT_EZ PF13513.6 GAM28874.1 - 0.0018 18.7 0.3 0.59 10.7 0.1 3.3 3 0 0 3 3 3 1 HEAT-like repeat PH_13 PF16652.5 GAM28874.1 - 0.0031 17.3 5.1 0.088 12.6 0.7 2.6 1 1 1 2 2 2 2 Pleckstrin homology domain PH_16 PF17838.1 GAM28874.1 - 0.039 13.8 2.7 0.3 10.9 0.8 2.8 2 1 0 2 2 2 0 PH domain HEAT PF02985.22 GAM28874.1 - 0.049 13.9 0.1 9.7 6.8 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat Telomere_reg-2 PF10193.9 GAM28874.1 - 0.058 13.9 2.3 0.59 10.6 0.4 3.1 3 0 0 3 3 3 0 Telomere length regulation protein GST_N_3 PF13417.6 GAM28875.1 - 3.4e-08 33.8 0.0 5.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM28875.1 - 5.1e-07 29.6 0.1 1e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAM28875.1 - 9.2e-07 29.0 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM28875.1 - 2.7e-05 24.4 0.0 4.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM28875.1 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain WD40 PF00400.32 GAM28876.1 - 2e-18 66.4 0.2 0.079 13.9 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM28876.1 - 2.4e-15 56.6 0.1 3.5e-07 30.4 0.0 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAM28876.1 - 0.0017 17.1 0.1 1.6 7.3 0.0 3.0 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 GAM28876.1 - 0.0025 16.9 0.3 0.052 12.6 0.0 2.1 1 1 2 3 3 3 1 Coatomer WD associated region BBS2_Mid PF14783.6 GAM28876.1 - 0.023 14.7 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 GAM28876.1 - 0.025 12.9 0.1 0.036 12.4 0.1 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 GAM28876.1 - 0.028 13.8 0.0 7.6 5.8 0.0 3.2 4 0 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 GAM28876.1 - 0.056 12.0 0.2 5.5 5.4 0.0 2.8 1 1 3 4 4 4 0 Cytochrome D1 heme domain Clavanin PF05452.11 GAM28876.1 - 0.059 13.6 0.3 0.24 11.6 0.1 2.0 2 0 0 2 2 2 0 Clavanin HPP PF04982.13 GAM28877.1 - 0.026 14.7 2.6 0.042 14.0 0.6 2.1 2 0 0 2 2 2 0 HPP family CTP_transf_1 PF01148.20 GAM28877.1 - 0.34 10.6 15.1 0.89 9.3 15.1 1.8 1 1 0 1 1 1 0 Cytidylyltransferase family DUF2304 PF10066.9 GAM28877.1 - 3 8.1 9.3 6 7.1 0.1 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) PPR_2 PF13041.6 GAM28878.1 - 1.5e-17 63.5 1.0 1.1e-09 38.4 0.1 4.2 2 1 2 4 4 4 3 PPR repeat family PPR PF01535.20 GAM28878.1 - 2.1e-10 40.1 0.8 0.2 12.0 0.0 4.3 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.6 GAM28878.1 - 6.5e-06 26.1 0.8 0.00018 21.5 0.1 2.8 1 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAM28878.1 - 0.00021 20.7 0.1 0.00052 19.4 0.0 1.5 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 GAM28878.1 - 0.00027 20.6 0.7 1.5 8.6 0.0 4.2 4 0 0 4 4 4 1 PPR repeat Ribosomal_S2 PF00318.20 GAM28879.1 - 1.2e-27 96.5 2.4 1.7e-14 53.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S18 PF01084.20 GAM28880.1 - 6.2e-15 55.1 0.0 3.4e-14 52.8 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S18 Peptidase_S13 PF02113.15 GAM28881.1 - 6.4e-79 265.7 0.0 7.6e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family ubiquitin PF00240.23 GAM28882.1 - 3.5e-07 29.9 0.1 0.0078 15.9 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 GAM28882.1 - 4.7e-05 23.1 0.1 0.017 14.9 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF1126 PF06565.12 GAM28882.1 - 0.09 12.6 0.6 0.94 9.3 0.3 2.0 1 1 1 2 2 2 0 DUF1126 PH-like domain ubiquitin PF00240.23 GAM28883.1 - 0.01 15.6 1.2 0.016 15.0 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin family PuR_N PF09182.10 GAM28884.1 - 0.13 12.2 0.1 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Zap1_zf2 PF18217.1 GAM28884.1 - 0.16 12.0 0.2 0.5 10.4 0.2 1.8 1 0 0 1 1 1 0 Zap1 zinc finger 2 LRR_8 PF13855.6 GAM28884.1 - 0.75 9.6 11.7 1.4 8.8 1.8 4.3 3 0 0 3 3 3 0 Leucine rich repeat FKBP_C PF00254.28 GAM28885.1 - 5e-17 62.0 0.0 1.2e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Spt20 PF12090.8 GAM28885.1 - 0.37 10.4 14.6 0.92 9.1 14.6 1.6 1 0 0 1 1 1 0 Spt20 family Methyltransf_32 PF13679.6 GAM28885.1 - 1.2 9.1 5.4 6.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Roughex PF06020.11 GAM28885.1 - 2.1 7.4 7.7 3.6 6.6 7.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein FNIP PF05725.12 GAM28886.1 - 2.3e-90 296.5 14.6 1.1e-10 41.5 0.1 8.6 5 2 3 8 8 8 8 FNIP Repeat HIRAN PF08797.11 GAM28886.1 - 0.0037 17.2 0.0 55 3.8 0.0 6.6 2 2 2 5 5 5 1 HIRAN domain Forkhead PF00250.18 GAM28887.1 - 0.0023 18.1 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain zf-RVT PF13966.6 GAM28887.1 - 0.13 13.0 0.4 0.39 11.5 0.4 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RFC1 PF08519.12 GAM28888.1 - 8.7e-37 126.7 0.1 3.8e-36 124.6 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 GAM28888.1 - 2.9e-15 56.4 0.0 9.2e-15 54.8 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 GAM28888.1 - 1.2e-13 51.7 1.8 2.1e-13 50.9 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAM28888.1 - 4.9e-07 29.9 0.0 3.1e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain PTCB-BRCT PF12738.7 GAM28888.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain RuvB_N PF05496.12 GAM28888.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAM28888.1 - 0.063 13.6 0.0 0.23 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAM28888.1 - 0.28 11.4 1.5 0.65 10.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain HATPase_c PF02518.26 GAM28889.1 - 7.2e-29 100.6 0.1 1.8e-28 99.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAM28889.1 - 1.2e-14 54.1 0.1 2.5e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 GAM28889.1 - 2.9e-14 53.2 0.0 1e-13 51.4 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 GAM28889.1 - 0.00031 21.0 0.1 0.00078 19.7 0.1 1.7 1 0 0 1 1 1 1 PAS domain GAF_2 PF13185.6 GAM28889.1 - 0.00084 19.7 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 GAF domain 4_1_CTD PF05902.13 GAM28889.1 - 0.069 13.2 0.5 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 4.1 protein C-terminal domain (CTD) HATPase_c_2 PF13581.6 GAM28889.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Ank_2 PF12796.7 GAM28891.1 - 0.0063 17.1 0.0 0.02 15.5 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28891.1 - 0.12 13.0 0.0 0.44 11.2 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Sod_Cu PF00080.20 GAM28892.1 - 8.2e-32 110.3 6.8 1.5e-25 90.0 0.4 3.3 3 0 0 3 3 3 2 Copper/zinc superoxide dismutase (SODC) FNIP PF05725.12 GAM28893.1 - 7.8e-37 125.2 14.5 7.9e-10 38.7 0.2 7.7 6 1 2 8 8 8 7 FNIP Repeat Choline_kin_N PF04428.14 GAM28893.1 - 0.0037 16.9 0.0 2.8 7.7 0.0 2.6 2 0 0 2 2 2 2 Choline kinase N terminus Adaptin_N PF01602.20 GAM28894.1 - 2.3e-149 498.3 14.0 3.2e-149 497.9 14.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAM28894.1 - 1.5e-66 223.4 5.8 6.7e-64 214.8 0.6 3.0 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAM28894.1 - 4.9e-18 65.3 1.6 1.5e-05 25.3 0.0 5.7 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 GAM28894.1 - 2e-09 36.9 4.3 0.079 13.3 0.0 6.3 5 0 0 5 5 5 2 HEAT repeat CLASP_N PF12348.8 GAM28894.1 - 8.6e-08 32.0 1.4 0.0056 16.3 0.1 4.1 3 2 0 3 3 3 2 CLASP N terminal Cnd3 PF12719.7 GAM28894.1 - 6.2e-06 25.6 1.7 0.00025 20.4 0.1 3.1 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 GAM28894.1 - 3.7e-05 23.9 6.1 1 9.6 0.0 5.1 2 2 3 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 GAM28894.1 - 0.0054 16.7 6.2 19 5.5 0.0 6.3 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat TPR_19 PF14559.6 GAM28894.1 - 0.01 16.3 0.5 0.11 13.0 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat UNC45-central PF11701.8 GAM28894.1 - 0.036 14.0 1.0 0.84 9.6 0.0 3.4 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central Arm_2 PF04826.13 GAM28894.1 - 0.037 13.5 3.6 0.16 11.4 0.0 3.2 3 0 0 3 3 3 0 Armadillo-like Mistic PF11458.8 GAM28894.1 - 0.23 11.5 5.5 1 9.4 0.2 3.3 3 0 0 3 3 3 0 Membrane-integrating protein Mistic dUTPase_2 PF08761.11 GAM28894.1 - 0.44 10.7 2.7 2.1 8.5 0.5 2.9 2 1 0 2 2 2 0 dUTPase B2-adapt-app_C PF09066.10 GAM28895.1 - 1.4e-22 79.9 0.9 1.8e-22 79.5 0.1 1.6 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Alpha_adaptinC2 PF02883.20 GAM28895.1 - 3.5e-05 24.1 0.2 7.2e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Ank_2 PF12796.7 GAM28896.1 - 6.7e-47 158.0 0.6 7e-12 45.8 0.0 4.9 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28896.1 - 1.5e-37 127.4 0.2 5.2e-08 33.3 0.0 7.0 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28896.1 - 3.3e-36 119.2 0.1 2.8e-05 24.2 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 GAM28896.1 - 4.7e-26 90.5 0.2 1.1e-05 25.6 0.0 6.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 GAM28896.1 - 1.6e-25 88.4 1.6 0.0007 19.9 0.2 9.9 10 0 0 10 10 10 7 Ankyrin repeat YfmQ PF10787.9 GAM28896.1 - 0.048 13.4 0.0 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein from bacillus cereus group PPR PF01535.20 GAM28896.1 - 0.052 13.8 0.0 4.8 7.6 0.0 3.2 3 0 0 3 3 3 0 PPR repeat Thaumatin PF00314.17 GAM28897.1 - 8.6e-80 267.4 12.8 9.8e-80 267.2 12.8 1.0 1 0 0 1 1 1 1 Thaumatin family Pico_P2A PF00947.19 GAM28897.1 - 0.0067 16.4 0.5 0.016 15.3 0.5 1.6 1 0 0 1 1 1 1 Picornavirus core protein 2A Eaf7 PF07904.13 GAM28898.1 - 3.9e-09 36.8 0.4 3.4e-08 33.8 0.4 2.0 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Barstar PF01337.18 GAM28898.1 - 0.093 12.8 0.3 9.4 6.3 0.2 2.1 1 1 1 2 2 2 0 Barstar (barnase inhibitor) Mito_carr PF00153.27 GAM28899.1 - 5.3e-65 215.4 6.7 6.2e-21 74.1 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAM28899.1 - 0.13 11.4 1.0 1.3 8.1 0.1 2.7 2 1 0 3 3 3 0 Gammaproteobacterial serine protease Hist_deacetyl PF00850.19 GAM28900.1 - 1.9e-90 303.4 0.3 3.7e-90 302.5 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Condensin2nSMC PF12422.8 GAM28900.1 - 0.0013 18.9 0.1 0.0032 17.6 0.1 1.6 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit AAA_22 PF13401.6 GAM28901.1 - 0.0073 16.6 0.1 0.072 13.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain TFB6 PF17110.5 GAM28902.1 - 2.4 7.9 6.8 4.4 7.0 6.8 1.4 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 GAM28902.1 - 3.4 5.8 8.2 4.2 5.5 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein FNIP PF05725.12 GAM28903.1 - 0.028 14.6 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 FNIP Repeat Lactamase_B_6 PF16661.5 GAM28904.1 - 2.3e-54 183.8 0.0 4e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 GAM28904.1 - 2.3e-24 86.5 1.6 1.1e-18 68.0 0.0 3.3 2 1 1 3 3 3 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 GAM28904.1 - 1e-16 61.2 0.0 2.3e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 GAM28904.1 - 7.5e-11 41.8 0.0 3.6e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 GAM28904.1 - 0.0032 17.5 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RCC1 PF00415.18 GAM28906.1 - 7.1e-56 186.6 14.2 9.9e-12 45.3 0.0 7.8 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM28906.1 - 6.5e-25 86.3 15.3 1.6e-05 24.6 0.0 8.4 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat TIR_2 PF13676.6 GAM28906.1 - 6.5e-05 23.5 0.3 0.076 13.6 0.2 3.3 2 1 0 2 2 2 2 TIR domain Nucleoside_tran PF01733.18 GAM28907.1 - 3.6e-48 164.5 19.9 9.1e-48 163.2 19.9 1.7 1 1 0 1 1 1 1 Nucleoside transporter DIOX_N PF14226.6 GAM28908.1 - 2.2e-23 83.3 0.0 3.1e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAM28908.1 - 2.4e-21 76.1 0.0 4.8e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Receptor_IA-2 PF11548.8 GAM28908.1 - 0.056 13.4 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 zf-UBR PF02207.20 GAM28909.1 - 0.00069 19.7 20.2 0.00069 19.7 20.2 4.0 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) LOH1CR12 PF10158.9 GAM28909.1 - 0.016 15.2 1.1 0.016 15.2 1.1 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Cupin_4 PF08007.12 GAM28910.1 - 3e-64 217.5 1.1 3.1e-64 217.5 0.0 1.5 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 GAM28910.1 - 2e-06 27.7 4.1 0.00013 21.7 4.1 2.9 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 GAM28910.1 - 0.00017 21.2 0.0 0.00036 20.2 0.0 1.5 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 GAM28910.1 - 0.0032 17.2 0.0 0.036 13.8 0.0 2.7 3 0 0 3 3 3 1 Cupin domain AAA PF00004.29 GAM28912.1 - 1.1e-41 142.3 0.0 1.8e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAM28912.1 - 1.9e-09 37.3 0.4 3.9e-09 36.3 0.4 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAM28912.1 - 6.8e-08 32.2 0.1 1.3e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 GAM28912.1 - 3.9e-06 27.2 0.4 0.0022 18.2 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 GAM28912.1 - 1.5e-05 25.2 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 GAM28912.1 - 3.1e-05 23.2 0.0 5.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 GAM28912.1 - 0.00011 22.2 1.1 0.00047 20.2 0.2 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM28912.1 - 0.0003 21.2 0.2 0.0018 18.7 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 GAM28912.1 - 0.00034 19.9 0.0 0.52 9.4 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain RuvB_N PF05496.12 GAM28912.1 - 0.00081 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 GAM28912.1 - 0.0045 16.4 0.2 0.3 10.4 0.1 2.3 1 1 1 2 2 2 1 KaiC Sigma54_activat PF00158.26 GAM28912.1 - 0.014 15.1 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 GAM28912.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 GAM28912.1 - 0.018 15.4 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 GAM28912.1 - 0.018 14.2 0.1 0.042 13.0 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 GAM28912.1 - 0.022 14.7 0.1 0.23 11.4 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_3 PF07726.11 GAM28912.1 - 0.023 14.5 0.0 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 GAM28912.1 - 0.033 13.6 0.1 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 GAM28912.1 - 0.04 14.1 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAM28912.1 - 0.044 13.3 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 GAM28912.1 - 0.049 13.3 0.3 0.13 12.0 0.3 1.8 1 1 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 GAM28912.1 - 0.058 13.1 2.1 0.097 12.3 0.1 2.4 3 0 0 3 3 2 0 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 GAM28912.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 GAM28912.1 - 0.079 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAM28912.1 - 0.082 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAM28912.1 - 0.16 11.6 0.4 1 8.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 GAM28912.1 - 0.19 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Thioredox_DsbH PF03190.15 GAM28913.1 - 5.1e-74 247.7 0.1 2.5e-73 245.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 GAM28913.1 - 1.7e-08 34.6 0.0 3.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.13 GAM28913.1 - 3.9e-08 33.0 1.8 0.00015 21.4 0.1 2.8 2 1 1 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.13 GAM28913.1 - 4.8e-05 22.6 2.1 0.24 10.4 0.1 3.1 2 2 1 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 GAM28913.1 - 0.011 15.3 0.2 0.096 12.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 DUF2193 PF09959.9 GAM28913.1 - 0.022 13.2 0.1 2.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2193) Pec_lyase PF09492.10 GAM28913.1 - 0.024 14.0 0.6 0.3 10.4 0.1 2.3 2 0 0 2 2 2 0 Pectic acid lyase Glyco_hydro_127 PF07944.12 GAM28913.1 - 0.053 12.0 0.9 2 6.8 0.1 2.4 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 zf-3CxxC PF13695.6 GAM28913.1 - 0.072 13.6 0.2 0.34 11.4 0.2 2.3 1 1 0 1 1 1 0 Zinc-binding domain S100PBPR PF15427.6 GAM28913.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 S100P-binding protein Ndr PF03096.14 GAM28914.1 - 1.2e-63 214.4 0.1 1.4e-63 214.2 0.1 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 GAM28914.1 - 6.6e-05 22.7 0.0 0.00017 21.3 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM28914.1 - 0.0035 16.7 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EIAV_GP90 PF00971.18 GAM28914.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 EIAV coat protein, gp90 RIO1 PF01163.22 GAM28915.1 - 3.2e-75 251.9 0.1 5.7e-75 251.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 GAM28915.1 - 0.00015 20.6 2.1 0.0002 20.2 2.1 1.6 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 GAM28915.1 - 0.0023 17.3 0.8 0.0039 16.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain ABC1 PF03109.16 GAM28915.1 - 0.081 13.1 0.1 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 ABC1 family RIO1 PF01163.22 GAM28916.1 - 9.5e-75 250.3 0.1 9.5e-75 250.3 0.1 1.9 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 GAM28916.1 - 5e-05 22.3 0.2 0.00015 20.7 0.2 1.7 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 GAM28916.1 - 0.0019 17.6 0.0 0.0063 15.9 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain DUF2796 PF10986.8 GAM28916.1 - 0.56 10.2 10.8 3.9 7.4 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) YL1 PF05764.13 GAM28916.1 - 5.4 7.1 42.3 5.8 7.0 22.7 2.4 2 0 0 2 2 2 0 YL1 nuclear protein Mtc PF03820.17 GAM28917.1 - 4.6e-114 380.7 0.0 5.1e-114 380.5 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier zf-DNL PF05180.12 GAM28918.1 - 3.8e-27 94.0 0.6 3.8e-27 94.0 0.6 2.2 2 0 0 2 2 2 1 DNL zinc finger Membralin PF09746.9 GAM28918.1 - 0.92 8.5 4.2 1.3 8.0 4.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein Presenilin PF01080.17 GAM28918.1 - 3.1 6.5 7.9 4 6.1 7.9 1.1 1 0 0 1 1 1 0 Presenilin Got1 PF04178.12 GAM28919.1 - 2.4e-12 47.2 14.5 3e-12 47.0 14.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3784 PF12650.7 GAM28919.1 - 0.16 12.2 11.0 1.2 9.4 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF1129 PF06570.11 GAM28919.1 - 1.9 7.9 6.0 2.3 7.7 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF202 PF02656.15 GAM28919.1 - 2.1 8.9 11.3 29 5.2 6.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF202) MR_MLE_C PF13378.6 GAM28921.1 - 1.4e-15 57.5 0.0 2.1e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAM28921.1 - 3.3e-05 24.1 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 2 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 GAM28921.1 - 0.00037 19.7 0.0 0.00056 19.1 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus HTH_45 PF14947.6 GAM28921.1 - 0.0028 17.6 0.1 0.0069 16.4 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix PHD_like PF12910.7 GAM28921.1 - 0.12 12.4 0.2 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system CBM49 PF09478.10 GAM28922.1 - 1.1e-13 51.3 0.4 1.7e-13 50.6 0.4 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 V-ATPase_C PF03223.15 GAM28923.1 - 4.2e-110 368.6 9.1 4.9e-110 368.4 9.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Ank_2 PF12796.7 GAM28924.1 - 2.8e-45 152.8 10.2 5.6e-14 52.5 0.1 3.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM28924.1 - 3.5e-22 78.2 0.9 5.7e-10 39.3 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28924.1 - 6.2e-22 75.3 0.9 4.3e-05 23.6 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 GAM28924.1 - 2.5e-21 75.7 1.4 1.7e-06 28.5 0.0 4.6 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM28924.1 - 6e-21 73.9 5.9 5e-05 23.6 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Exo_endo_phos PF03372.23 GAM28925.1 - 4.3e-10 39.5 0.0 1.5e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 GAM28925.1 - 0.017 15.0 0.0 0.28 11.0 0.0 2.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF4614 PF15391.6 GAM28925.1 - 0.17 11.9 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Ectatomin PF06457.11 GAM28925.1 - 0.18 11.8 0.7 0.33 10.9 0.7 1.4 1 0 0 1 1 1 0 Ectatomin PIG-Y PF15159.6 GAM28926.1 - 4e-19 69.3 8.3 7.3e-19 68.5 8.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DLIC PF05783.11 GAM28926.1 - 0.0038 16.1 2.8 0.0038 16.1 2.8 1.3 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) YlqD PF11068.8 GAM28926.1 - 0.86 10.0 12.6 1.2 9.5 12.6 1.2 1 0 0 1 1 1 0 YlqD protein TFIIA PF03153.13 GAM28926.1 - 5.6 6.8 21.9 6.8 6.6 21.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VPS28 PF03997.12 GAM28927.1 - 9.3e-68 227.6 4.6 1.1e-67 227.3 4.6 1.1 1 0 0 1 1 1 1 VPS28 protein RFC1 PF08519.12 GAM28927.1 - 0.0017 18.5 0.4 0.15 12.2 0.1 2.3 1 1 1 2 2 2 2 Replication factor RFC1 C terminal domain Spt4 PF06093.13 GAM28928.1 - 7.8e-26 90.0 0.4 9.8e-26 89.7 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Zn-ribbon_8 PF09723.10 GAM28928.1 - 0.046 13.8 1.0 0.67 10.1 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain CsbD PF05532.12 GAM28929.1 - 0.00012 21.9 2.8 0.00026 20.8 0.2 2.2 2 0 0 2 2 2 1 CsbD-like Trimer_CC PF08954.11 GAM28929.1 - 0.46 10.1 2.4 4.8 6.8 0.6 2.6 3 0 0 3 3 3 0 Trimerisation motif Arm PF00514.23 GAM28930.1 - 1e-37 127.0 9.6 2.5e-09 36.8 0.1 9.4 9 1 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 GAM28930.1 - 6.6e-12 45.7 0.0 0.00015 22.2 0.0 6.0 6 1 1 7 7 7 2 HEAT-like repeat HEAT PF02985.22 GAM28930.1 - 1.2e-07 31.4 0.0 0.0092 16.2 0.0 5.2 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 GAM28930.1 - 0.001 19.4 0.0 5.3 7.5 0.0 4.2 1 1 2 4 4 4 1 HEAT repeats RICTOR_V PF14668.6 GAM28930.1 - 0.0052 17.0 5.7 0.97 9.7 0.1 5.1 5 1 1 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Macscav_rec PF03523.13 GAM28930.1 - 0.024 14.5 0.0 0.11 12.4 0.0 2.2 1 0 0 1 1 1 0 Macrophage scavenger receptor RNase_E_G PF10150.9 GAM28930.1 - 0.046 13.1 0.2 0.074 12.5 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease E/G family BDM PF10684.9 GAM28930.1 - 0.061 13.7 1.1 13 6.2 0.0 3.0 3 0 0 3 3 3 0 Putative biofilm-dependent modulation protein Pkinase PF00069.25 GAM28931.1 - 4.4e-72 242.6 0.0 9.6e-72 241.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28931.1 - 2.1e-48 164.9 0.0 4.2e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM28931.1 - 4.5e-07 29.0 0.0 4.5e-07 29.0 0.0 2.6 2 1 1 3 3 3 1 Fungal protein kinase Kdo PF06293.14 GAM28931.1 - 0.0009 18.7 0.1 0.0017 17.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sif PF06767.11 GAM28931.1 - 0.0088 15.1 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 Sif protein FTA2 PF13095.6 GAM28931.1 - 0.055 13.1 0.1 0.055 13.1 0.1 2.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 HSM3_C PF18794.1 GAM28931.1 - 0.067 12.8 0.3 0.15 11.6 0.3 1.5 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, C terminal domain PB1-F2 PF11986.8 GAM28931.1 - 0.46 10.7 3.2 1.1 9.5 0.1 2.9 3 0 0 3 3 3 0 Influenza A Proapoptotic protein CCDC66 PF15236.6 GAM28931.1 - 1.3 8.8 19.2 1.2 8.9 0.4 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 Calc_CGRP_IAPP PF00214.19 GAM28931.1 - 1.6 9.1 5.3 0.33 11.3 0.8 2.2 3 0 0 3 3 3 0 Calcitonin / CGRP / IAPP family Peptidase_S49_N PF08496.10 GAM28931.1 - 9.3 6.3 18.5 1.9 8.5 0.3 2.9 3 0 0 3 3 3 0 Peptidase family S49 N-terminal DUF1298 PF06974.13 GAM28932.1 - 0.011 15.6 1.5 0.014 15.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) COX3 PF00510.18 GAM28932.1 - 0.02 14.7 0.3 0.024 14.5 0.3 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit III UQ_con PF00179.26 GAM28933.1 - 1.2e-46 157.9 0.1 1.4e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 GAM28933.1 - 1.4e-05 24.9 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 GAM28933.1 - 0.0011 19.3 0.1 0.0016 18.7 0.1 1.3 1 1 0 1 1 1 1 RWD domain DICT PF10069.9 GAM28934.1 - 0.02 14.7 1.2 0.022 14.5 1.2 1.1 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system Otopetrin PF03189.13 GAM28934.1 - 0.43 9.4 8.1 0.51 9.1 8.1 1.0 1 0 0 1 1 1 0 Otopetrin Pox_Ag35 PF03286.14 GAM28934.1 - 0.71 9.6 10.3 0.78 9.5 10.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 GAM28934.1 - 8.4 5.0 7.8 8.9 5.0 7.8 1.0 1 0 0 1 1 1 0 Presenilin p450 PF00067.22 GAM28935.1 - 0.09 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 Sen15 PF09631.10 GAM28936.1 - 2.5e-10 40.6 0.8 5.8e-10 39.4 0.2 1.9 2 1 0 2 2 2 1 Sen15 protein Ribosomal_S11 PF00411.19 GAM28936.1 - 0.12 12.8 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S11 GATA PF00320.27 GAM28937.1 - 2.2e-14 52.8 5.7 5.2e-14 51.6 5.7 1.6 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 GAM28937.1 - 0.53 10.6 2.7 1.3 9.3 2.7 1.7 1 0 0 1 1 1 0 zinc-ribbon PSI PF01437.25 GAM28938.1 - 0.00061 20.3 14.3 0.0011 19.4 14.3 1.5 1 0 0 1 1 1 1 Plexin repeat CTV_P6 PF06706.11 GAM28938.1 - 0.00074 19.2 3.7 0.0016 18.1 3.7 1.5 1 0 0 1 1 1 1 Citrus tristeza virus 6-kDa protein Shisa PF13908.6 GAM28938.1 - 0.0021 18.4 6.5 0.003 17.8 6.3 1.5 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator CD34_antigen PF06365.12 GAM28938.1 - 0.0031 17.1 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Rax2 PF12768.7 GAM28938.1 - 0.015 14.8 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Alpha_E2_glycop PF00943.19 GAM28938.1 - 0.019 13.7 0.6 0.019 13.7 0.6 1.6 2 0 0 2 2 2 0 Alphavirus E2 glycoprotein EphA2_TM PF14575.6 GAM28938.1 - 0.043 14.7 0.0 0.71 10.8 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PSI_integrin PF17205.3 GAM28938.1 - 0.064 13.0 10.8 0.14 12.0 10.8 1.6 1 0 0 1 1 1 0 Integrin plexin domain DUF4148 PF13663.6 GAM28938.1 - 0.082 13.1 0.3 6.6 7.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) ODV-E18 PF10717.9 GAM28938.1 - 4.2 7.3 5.4 20 5.1 0.2 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Pro-kuma_activ PF09286.11 GAM28939.1 - 1.6e-28 99.8 0.7 3e-28 98.9 0.1 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAM28939.1 - 7.6e-07 28.7 1.3 7.6e-07 28.7 1.3 2.0 2 0 0 2 2 2 1 Subtilase family FAM110_C PF14160.6 GAM28939.1 - 0.083 14.0 0.0 0.38 11.8 0.0 2.0 2 0 0 2 2 2 0 Centrosome-associated C terminus LIM PF00412.22 GAM28940.1 - 1.6e-15 57.0 3.7 1.6e-15 57.0 3.7 1.9 2 0 0 2 2 2 1 LIM domain zf-B_box PF00643.24 GAM28940.1 - 0.028 14.6 8.4 0.065 13.4 1.6 2.8 2 1 1 3 3 3 0 B-box zinc finger zf-C3HC4_4 PF15227.6 GAM28940.1 - 0.037 14.2 1.5 0.037 14.2 1.5 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING HNH PF01844.23 GAM28940.1 - 0.19 11.9 5.1 0.27 11.4 2.5 2.4 2 1 0 2 2 2 0 HNH endonuclease DZR PF12773.7 GAM28940.1 - 0.23 11.5 8.2 56 3.9 8.4 2.5 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_L37ae PF01780.19 GAM28940.1 - 0.31 11.2 4.4 2 8.5 4.4 2.1 1 1 0 1 1 1 0 Ribosomal L37ae protein family zf-RING_5 PF14634.6 GAM28940.1 - 0.38 10.7 7.2 0.28 11.2 0.7 2.5 2 2 0 2 2 2 0 zinc-RING finger domain zf-dskA_traR PF01258.17 GAM28940.1 - 1.1 9.3 8.8 4.2 7.4 0.1 2.9 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger Zn_Tnp_IS1595 PF12760.7 GAM28940.1 - 2.2 8.3 10.0 0.65 10.0 2.5 2.5 1 1 1 2 2 2 0 Transposase zinc-ribbon domain HNH_5 PF14279.6 GAM28940.1 - 2.6 8.0 8.4 0.56 10.1 2.6 2.6 1 1 1 2 2 2 0 HNH endonuclease LIM PF00412.22 GAM28941.1 - 2.3e-25 88.6 18.5 1.6e-12 47.4 2.8 2.4 2 0 0 2 2 2 2 LIM domain WSD PF15613.6 GAM28941.1 - 0.038 14.5 0.8 1.9 9.0 0.1 2.8 3 0 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Pex19 PF04614.12 GAM28941.1 - 0.4 10.4 6.6 0.15 11.8 3.3 1.9 1 1 1 2 2 2 0 Pex19 protein family Calpain_inhib PF00748.19 GAM28941.1 - 1.9 9.0 25.8 1.6 9.3 7.2 3.1 1 1 2 3 3 3 0 Calpain inhibitor TFIIA PF03153.13 GAM28941.1 - 2.7 7.9 25.3 3.3 7.6 25.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GET2 PF08690.10 GAM28941.1 - 8.4 6.0 19.7 9.1 5.9 4.8 2.3 1 1 1 2 2 2 0 GET complex subunit GET2 BRCT_2 PF16589.5 GAM28942.1 - 2e-20 73.0 0.2 5.5e-13 49.1 0.0 3.2 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAM28942.1 - 8.1e-18 64.6 0.8 1.5e-10 41.3 0.1 3.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 GAM28942.1 - 1.8e-09 37.4 0.0 1.8e-09 37.4 0.0 5.5 5 2 0 5 5 5 2 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 GAM28942.1 - 3.4e-06 26.9 0.5 1.6e-05 24.8 0.2 2.2 2 0 0 2 2 2 1 twin BRCT domain Methyltransf_16 PF10294.9 GAM28943.1 - 2.5e-21 76.2 0.0 3.5e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAM28943.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 GAM28943.1 - 0.03 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 GAM28943.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 GAM28943.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TIG PF01833.24 GAM28945.1 - 1e-05 25.5 17.4 0.001 19.1 3.6 5.1 4 1 1 5 5 5 2 IPT/TIG domain LRR_4 PF12799.7 GAM28945.1 - 0.00065 20.1 4.2 0.0026 18.1 0.3 4.3 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) EB PF01683.18 GAM28945.1 - 0.0015 18.8 3.9 0.0046 17.2 3.9 1.8 1 0 0 1 1 1 1 EB module EGF_Tenascin PF18720.1 GAM28945.1 - 0.0068 16.4 4.0 0.017 15.2 4.0 1.7 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 GAM28945.1 - 0.021 15.2 16.3 0.048 14.0 16.3 1.6 1 0 0 1 1 1 0 EGF-like domain LRR_8 PF13855.6 GAM28945.1 - 0.12 12.2 1.6 1.1 9.1 0.1 3.2 1 1 0 2 2 2 0 Leucine rich repeat Insulin_TMD PF17870.1 GAM28945.1 - 1.3 9.2 7.1 0.13 12.4 1.6 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment FNIP PF05725.12 GAM28947.1 - 2.5e-32 110.8 11.8 7.6e-10 38.8 0.0 7.7 4 2 3 8 8 8 7 FNIP Repeat F-box PF00646.33 GAM28947.1 - 0.021 14.7 0.5 0.24 11.3 0.5 2.8 2 0 0 2 2 2 0 F-box domain F-box_5 PF18511.1 GAM28947.1 - 0.032 13.8 0.1 0.13 11.8 0.2 1.9 2 0 0 2 2 2 0 F-box FNIP PF05725.12 GAM28948.1 - 7.9e-48 160.4 20.9 3.2e-13 49.6 0.4 5.7 2 2 2 5 5 5 5 FNIP Repeat DUF1769 PF08588.10 GAM28948.1 - 0.088 13.0 0.5 31 4.9 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1769) EB PF01683.18 GAM28949.1 - 0.0012 19.0 2.8 0.0027 18.0 2.8 1.5 1 0 0 1 1 1 1 EB module CBM77 PF18283.1 GAM28949.1 - 0.0058 17.0 1.0 0.12 12.7 0.0 3.0 3 0 0 3 3 3 1 Carbohydrate binding module 77 Phage_Coat_Gp8 PF05371.12 GAM28949.1 - 0.096 12.5 2.5 0.12 12.2 0.7 2.0 2 0 0 2 2 2 0 Phage major coat protein, Gp8 EGF_2 PF07974.13 GAM28949.1 - 1.9 8.9 13.3 4 7.9 13.3 1.5 1 0 0 1 1 1 0 EGF-like domain Peptidase_M66 PF10462.9 GAM28950.1 - 2.1e-82 276.5 1.0 2.7e-82 276.1 1.0 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 GAM28950.1 - 0.011 16.2 0.2 0.031 14.8 0.2 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 GAM28950.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 GAM28950.1 - 0.078 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 GAM28950.1 - 0.13 10.8 1.0 0.21 10.2 1.0 1.1 1 0 0 1 1 1 0 Putative peptidase family LRR_4 PF12799.7 GAM28952.1 - 4.9e-05 23.6 1.2 0.00021 21.6 1.2 2.2 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) EB PF01683.18 GAM28952.1 - 7.2e-05 23.0 3.3 0.00018 21.7 3.3 1.7 1 0 0 1 1 1 1 EB module LRR_8 PF13855.6 GAM28952.1 - 0.00021 21.0 0.5 0.00076 19.2 0.1 2.2 2 0 0 2 2 2 1 Leucine rich repeat EGF_Tenascin PF18720.1 GAM28952.1 - 1.6 8.8 7.7 4.5 7.4 7.7 1.8 1 0 0 1 1 1 0 Tenascin EGF domain eIF2A PF08662.11 GAM28955.1 - 6.1e-58 195.9 0.1 5.7e-57 192.7 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Caerin_1 PF07440.12 GAM28955.1 - 0.11 12.6 0.6 0.27 11.4 0.6 1.6 1 0 0 1 1 1 0 Caerin 1 protein DMAP1 PF05499.12 GAM28955.1 - 0.15 11.9 4.8 0.48 10.3 4.8 1.8 1 1 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) BSD PF03909.17 GAM28956.1 - 1.3e-07 31.5 0.7 7.9e-07 29.0 0.7 2.4 1 0 0 1 1 1 1 BSD domain RCC1 PF00415.18 GAM28957.1 - 1.3e-59 198.6 7.1 5.2e-13 49.4 0.0 7.1 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAM28957.1 - 9.2e-34 114.5 24.8 1.9e-08 33.9 0.4 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos PF03372.23 GAM28957.1 - 2.3e-17 63.3 0.0 3.9e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNA_pol_A_bac PF01000.26 GAM28958.1 - 2.7e-29 101.8 0.1 5.2e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAM28958.1 - 7e-25 86.3 0.0 1.4e-24 85.3 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 GAM28958.1 - 0.024 14.8 1.0 0.064 13.4 1.0 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Rep_fac_C PF08542.11 GAM28959.1 - 2.3e-21 76.0 0.4 2.7e-20 72.6 0.1 2.5 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 GAM28959.1 - 4.3e-18 66.0 0.1 2.5e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GAM28959.1 - 1.1e-13 51.3 0.0 1.2e-10 41.4 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 GAM28959.1 - 3.7e-09 36.8 0.0 7.9e-08 32.4 0.0 2.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 GAM28959.1 - 8.3e-06 26.3 0.0 0.00039 20.8 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAM28959.1 - 1.6e-05 24.7 0.8 9.4e-05 22.2 0.0 2.5 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 GAM28959.1 - 2.9e-05 24.3 0.0 8.5e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 GAM28959.1 - 3.2e-05 24.2 0.1 0.016 15.5 0.1 2.9 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 GAM28959.1 - 5.3e-05 23.2 0.5 0.00021 21.3 0.0 2.3 3 1 0 3 3 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAM28959.1 - 6.1e-05 22.6 0.5 0.00014 21.5 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 GAM28959.1 - 8.2e-05 22.6 0.0 0.0002 21.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 GAM28959.1 - 0.0001 22.1 0.0 0.00041 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAM28959.1 - 0.00018 20.7 0.0 0.00032 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 GAM28959.1 - 0.00019 21.2 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM28959.1 - 0.00033 20.5 0.2 0.0014 18.5 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.11 GAM28959.1 - 0.00051 19.9 0.0 0.0016 18.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 GAM28959.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 GAM28959.1 - 0.0024 18.2 0.2 0.046 14.1 0.0 2.4 2 1 1 3 3 2 1 AAA domain DNA_pol3_delta PF06144.13 GAM28959.1 - 0.0024 17.7 0.4 0.0061 16.3 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_18 PF13238.6 GAM28959.1 - 0.004 17.7 0.0 0.0098 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 GAM28959.1 - 0.0058 17.2 0.1 0.025 15.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain ATPase_2 PF01637.18 GAM28959.1 - 0.0063 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TniB PF05621.11 GAM28959.1 - 0.0098 15.3 0.0 1.2 8.5 0.0 2.4 1 1 1 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 GAM28959.1 - 0.012 16.0 0.0 0.035 14.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 GAM28959.1 - 0.016 15.2 0.0 0.35 10.8 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 GAM28959.1 - 0.017 15.1 0.0 1.1 9.2 0.0 3.1 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.6 GAM28959.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAM28959.1 - 0.029 14.1 0.0 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 GAM28959.1 - 0.031 13.6 0.0 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAM28959.1 - 0.035 13.8 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DEAD PF00270.29 GAM28959.1 - 0.045 13.5 0.7 0.31 10.8 0.1 2.5 2 1 1 3 3 2 0 DEAD/DEAH box helicase NB-ARC PF00931.22 GAM28959.1 - 0.049 12.8 0.0 0.27 10.4 0.0 2.2 1 1 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 GAM28959.1 - 0.09 13.3 0.1 0.71 10.4 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 GAM28959.1 - 0.095 12.9 0.0 0.3 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain Cullin_Nedd8 PF10557.9 GAM28959.1 - 0.17 11.9 6.4 16 5.7 0.4 4.2 3 2 2 5 5 5 0 Cullin protein neddylation domain FNIP PF05725.12 GAM28960.1 - 1.4e-40 137.2 11.9 9.3e-09 35.3 0.1 10.4 8 2 2 10 10 10 9 FNIP Repeat Pkinase PF00069.25 GAM28961.1 - 6.7e-39 133.8 0.0 7.8e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM28961.1 - 5.7e-15 55.3 0.0 1.8e-12 47.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM28961.1 - 1.8e-05 23.7 0.0 2.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAM28961.1 - 0.0021 17.4 0.0 0.0088 15.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 GAM28961.1 - 0.0059 16.6 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAM28961.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAM28961.1 - 0.18 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 GAM28962.1 - 0.014 14.8 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain betaPIX_CC PF16523.5 GAM28962.1 - 0.097 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 betaPIX coiled coil Mlf1IP PF10248.9 GAM28963.1 - 2e-09 37.7 37.5 7.5e-09 35.8 20.1 3.1 2 1 0 2 2 2 2 Myelodysplasia-myeloid leukemia factor 1-interacting protein SR-25 PF10500.9 GAM28963.1 - 0.0039 16.8 25.4 0.016 14.8 9.5 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF1645 PF07816.11 GAM28963.1 - 0.23 12.0 11.1 1.2 9.7 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) CDT1_C PF16679.5 GAM28963.1 - 0.67 10.4 6.9 0.35 11.3 3.0 2.3 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain DUF3446 PF11928.8 GAM28963.1 - 0.72 10.2 24.3 0.27 11.5 2.2 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Lin-8 PF03353.15 GAM28963.1 - 1.3 8.5 36.8 0.36 10.3 11.0 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Chorion_2 PF03964.15 GAM28963.1 - 8.8 7.2 18.8 5.1 8.0 5.0 3.2 3 0 0 3 3 3 0 Chorion family 2 GCN5L1 PF06320.13 GAM28964.1 - 3.2e-44 149.7 3.3 4.2e-44 149.3 3.3 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF3130 PF11328.8 GAM28964.1 - 0.027 14.7 0.6 0.11 12.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3130 SoPB_HTH PF18090.1 GAM28964.1 - 0.06 13.5 0.0 0.32 11.1 0.0 2.0 1 1 0 2 2 2 0 Centromere-binding protein HTH domain Hemocyanin_M PF00372.19 GAM28964.1 - 0.088 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Hemocyanin, copper containing domain DUF948 PF06103.11 GAM28964.1 - 0.48 10.7 4.8 1.3 9.4 0.9 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Dickkopf_N PF04706.12 GAM28965.1 - 0.0016 18.9 1.0 0.0016 18.9 1.0 3.8 3 2 1 4 4 4 1 Dickkopf N-terminal cysteine-rich region Prokineticin PF06607.11 GAM28965.1 - 0.012 15.9 1.5 0.012 15.9 1.5 2.7 2 1 0 3 3 3 0 Prokineticin FNIP PF05725.12 GAM28966.1 - 1.5e-25 89.1 18.0 7.3e-08 32.5 0.0 7.4 7 1 2 9 9 9 6 FNIP Repeat TerD PF02342.18 GAM28966.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 TerD domain Peptidase_M8 PF01457.16 GAM28968.1 - 3.2e-58 197.7 0.3 5e-58 197.1 0.3 1.2 1 0 0 1 1 1 1 Leishmanolysin PRR18 PF15671.5 GAM28968.1 - 8.4 6.2 14.2 11 5.8 11.5 2.2 2 0 0 2 2 2 0 Proline-rich protein family 18 Methyltransf_11 PF08241.12 GAM28969.1 - 8.8e-14 51.9 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM28969.1 - 2.5e-10 40.9 0.0 1.7e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAM28969.1 - 3.2e-08 33.5 0.1 4.4e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM28969.1 - 1.6e-07 32.0 0.0 2.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM28969.1 - 6.4e-05 22.8 0.0 9.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAM28969.1 - 0.00033 20.1 0.1 0.00061 19.2 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 GAM28969.1 - 0.00082 19.4 0.0 0.00093 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 GAM28969.1 - 0.0055 16.5 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 1 DNA methylase Methyltransf_8 PF05148.15 GAM28969.1 - 0.009 15.9 0.0 2.1 8.1 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase MTS PF05175.14 GAM28969.1 - 0.028 13.9 0.0 0.28 10.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Acyltransf_C PF16076.5 GAM28970.1 - 2.9e-21 75.3 0.3 4.6e-21 74.7 0.3 1.3 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 GAM28970.1 - 4.4e-15 55.5 0.0 7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PEGSRP PF07623.11 GAM28970.1 - 0.89 9.4 3.0 0.44 10.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) RhoGEF PF00621.20 GAM28971.1 - 2e-37 129.2 2.2 2e-37 129.2 2.2 1.7 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 GAM28971.1 - 7.7e-20 70.8 7.7 1.6e-19 69.8 7.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 GAM28971.1 - 1.9e-08 34.8 1.6 3.9e-08 33.7 0.2 2.3 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 GAM28971.1 - 2.2e-05 24.3 0.3 5.7e-05 23.0 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain FYVE_2 PF02318.16 GAM28971.1 - 0.01 16.1 4.8 0.036 14.3 4.8 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger PH_12 PF16457.5 GAM28971.1 - 0.3 11.6 3.7 0.3 11.6 0.2 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain zf-B_box PF00643.24 GAM28971.1 - 0.78 10.0 4.3 1.7 8.9 4.3 1.5 1 0 0 1 1 1 0 B-box zinc finger Cytochrom_B558a PF05038.13 GAM28972.1 - 9.9e-09 35.0 8.9 1.2e-08 34.8 1.1 2.0 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit PigN PF04987.14 GAM28972.1 - 0.015 14.2 5.2 0.018 14.0 5.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF308 PF03729.13 GAM28972.1 - 0.016 15.5 11.4 0.27 11.6 3.1 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) TMEM72 PF16054.5 GAM28972.1 - 0.1 12.3 9.3 0.89 9.2 1.1 2.0 1 1 1 2 2 2 0 Transmembrane protein family 72 DUF4064 PF13273.6 GAM28972.1 - 1.6 9.0 12.7 12 6.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Gate PF07670.14 GAM28972.1 - 5 7.5 10.0 10 6.4 8.9 2.0 1 1 0 1 1 1 0 Nucleoside recognition DUF1794 PF08768.11 GAM28973.1 - 2.8e-28 98.8 0.1 3.1e-28 98.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) Ribosomal_L6e PF01159.19 GAM28974.1 - 4.7e-17 62.5 1.1 8.2e-17 61.7 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 GAM28974.1 - 0.16 12.3 0.3 0.16 12.3 0.3 2.7 3 0 0 3 3 3 0 Ribosomal protein L6, N-terminal domain OAD_gamma PF04277.13 GAM28974.1 - 9.1 7.0 7.5 2.4 8.8 2.4 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF2838 PF10998.8 GAM28975.1 - 8.6e-37 125.8 8.0 8.6e-37 125.8 8.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2838) GATA PF00320.27 GAM28976.1 - 1.5e-13 50.1 7.3 2.8e-13 49.2 7.3 1.5 1 0 0 1 1 1 1 GATA zinc finger KH_8 PF17903.1 GAM28977.1 - 3.2e-06 27.1 0.0 1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 GAM28977.1 - 0.0013 18.5 0.5 0.0013 18.5 0.5 1.9 2 0 0 2 2 2 1 KH domain pKID PF02173.17 GAM28978.1 - 0.026 14.0 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 pKID domain Aminotran_5 PF00266.19 GAM28979.1 - 6.1e-41 140.6 0.0 9.7e-41 139.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAM28979.1 - 0.00021 20.0 0.0 0.00029 19.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAM28979.1 - 0.00068 19.0 0.0 0.0058 16.0 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family PALP PF00291.25 GAM28979.1 - 0.00072 19.1 0.0 0.0044 16.5 0.0 2.0 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Pyridoxal_deC PF00282.19 GAM28979.1 - 0.01 14.6 0.8 0.096 11.4 0.1 2.5 3 0 0 3 3 3 0 Pyridoxal-dependent decarboxylase conserved domain DUF3827 PF12877.7 GAM28980.1 - 0.021 13.2 3.3 0.031 12.6 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EGF PF00008.27 GAM28980.1 - 0.023 15.0 11.5 0.05 13.9 11.5 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 GAM28980.1 - 0.027 14.5 8.6 0.085 12.9 8.6 1.9 1 0 0 1 1 1 0 Tenascin EGF domain TIG PF01833.24 GAM28980.1 - 0.052 13.6 13.4 0.031 14.3 2.0 3.7 2 1 1 3 3 3 0 IPT/TIG domain EGF_2 PF07974.13 GAM28980.1 - 0.072 13.5 15.7 0.16 12.3 15.7 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 GAM28980.1 - 0.22 12.2 6.5 0.68 10.7 6.5 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF SKG6 PF08693.10 GAM28980.1 - 1.9 8.0 11.6 3.6 7.1 11.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain 2OG-FeII_Oxy_2 PF13532.6 GAM28981.1 - 1.1e-21 77.9 0.0 1.3e-21 77.7 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Arm PF00514.23 GAM28983.1 - 0.00013 21.9 3.1 0.0083 16.1 0.0 3.2 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 GAM28983.1 - 0.21 11.6 1.5 1.8 8.6 0.1 2.7 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain FAD-oxidase_C PF02913.19 GAM28984.1 - 1.1e-53 182.4 0.0 1.7e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAM28984.1 - 1.2e-37 128.8 0.0 2.1e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain LRR_4 PF12799.7 GAM28985.1 - 1.2 9.7 6.5 1 9.9 3.0 2.7 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Laminin_EGF PF00053.24 GAM28985.1 - 5 7.4 6.7 0.55 10.4 2.1 1.7 2 0 0 2 2 2 0 Laminin EGF domain TMEM43 PF07787.12 GAM28986.1 - 1.4 8.2 3.1 2.1 7.7 3.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 TraS PF10624.9 GAM28986.1 - 2.2 8.2 5.9 3.4 7.6 5.9 1.2 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS SPC12 PF06645.13 GAM28987.1 - 1.5e-17 63.4 4.7 1.6e-17 63.3 4.7 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Ank_2 PF12796.7 GAM28988.1 - 8.8e-45 151.2 28.5 3.3e-09 37.2 0.5 8.4 4 3 6 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM28988.1 - 1.1e-40 137.2 33.0 0.0039 17.5 0.0 16.4 4 3 13 17 17 17 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM28988.1 - 4.1e-35 119.7 25.9 0.00026 21.5 0.0 13.3 5 4 9 14 14 14 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28988.1 - 5.7e-22 75.5 18.4 3.5 8.5 0.0 16.8 15 3 4 19 19 19 4 Ankyrin repeat Ank PF00023.30 GAM28988.1 - 2.7e-07 30.7 14.0 23 5.6 0.2 12.8 9 3 2 11 11 11 0 Ankyrin repeat DUF4031 PF13223.6 GAM28988.1 - 0.0067 16.6 3.4 60 4.0 0.1 5.2 4 2 2 6 6 6 0 Protein of unknown function (DUF4031) Tom37 PF10568.9 GAM28988.1 - 0.011 16.0 3.1 22 5.4 0.0 5.6 2 2 2 6 6 6 0 Outer mitochondrial membrane transport complex protein ENTH PF01417.20 GAM28988.1 - 0.045 13.8 0.3 12 6.0 0.0 4.4 2 2 2 5 5 5 0 ENTH domain Chlorophyllase PF07224.11 GAM28988.1 - 0.14 11.2 3.2 2.4 7.1 0.2 3.8 3 1 0 4 4 4 0 Chlorophyllase Serglycin PF04360.12 GAM28989.1 - 0.076 13.0 0.6 0.13 12.2 0.6 1.4 1 0 0 1 1 1 0 Serglycin PMI_typeI PF01238.21 GAM28990.1 - 3.9e-103 345.5 0.0 4.8e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 GAM28990.1 - 0.00039 20.3 0.0 0.66 9.9 0.0 3.0 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_2 PF07883.11 GAM28990.1 - 0.0024 17.5 0.0 0.31 10.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 GAM28990.1 - 0.012 15.2 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 Cupin AAA_13 PF13166.6 GAM28991.1 - 0.00032 19.5 32.5 0.00032 19.5 32.5 4.4 1 1 2 4 4 4 2 AAA domain DUF1664 PF07889.12 GAM28991.1 - 0.0015 18.6 5.3 0.0015 18.6 5.3 9.2 2 1 6 9 9 9 2 Protein of unknown function (DUF1664) MCC-bdg_PDZ PF10506.9 GAM28991.1 - 0.0033 17.4 1.2 0.0033 17.4 1.2 8.2 5 1 6 11 11 11 1 PDZ domain of MCC-2 bdg protein for Usher syndrome IFT57 PF10498.9 GAM28991.1 - 0.006 15.6 9.2 0.006 15.6 9.2 7.1 1 1 6 7 7 7 3 Intra-flagellar transport protein 57 DUF4200 PF13863.6 GAM28991.1 - 0.006 17.0 9.5 0.006 17.0 9.5 10.1 2 1 10 12 12 12 3 Domain of unknown function (DUF4200) Filament PF00038.21 GAM28991.1 - 0.73 9.4 146.5 0.83 9.2 37.4 6.1 1 1 4 5 5 5 0 Intermediate filament protein Fez1 PF06818.15 GAM28991.1 - 1.7 9.0 143.9 0.016 15.6 22.6 6.5 1 1 6 7 7 7 0 Fez1 DUF4407 PF14362.6 GAM28991.1 - 3.9 6.7 108.2 0.04 13.3 21.1 6.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 GAM28991.1 - 6.3 6.8 176.2 0.28 11.2 13.6 10.8 2 1 9 11 11 11 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 GAM28991.1 - 7.5 5.3 160.4 0.087 11.7 13.1 7.6 1 1 6 7 7 7 0 Spc7 kinetochore protein UCH PF00443.29 GAM28993.1 - 2.1e-51 174.9 0.0 5.1e-51 173.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAM28993.1 - 6e-08 32.6 21.3 1.6e-06 27.9 0.0 4.0 4 2 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase DUF4428 PF14471.6 GAM28993.1 - 0.00055 19.8 1.7 0.22 11.5 0.4 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4428) zf-C4_ClpX PF06689.13 GAM28993.1 - 0.0096 15.8 0.6 9.5 6.2 0.1 3.5 3 0 0 3 3 3 1 ClpX C4-type zinc finger SR-25 PF10500.9 GAM28993.1 - 4.9 6.7 40.3 1.1 8.9 9.0 4.7 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein Ribosomal_L2_C PF03947.18 GAM28994.1 - 2.1e-46 157.2 3.4 3.7e-46 156.4 3.4 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 GAM28994.1 - 1.1e-20 73.3 0.0 5.2e-20 71.2 0.0 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain zf-C2H2_4 PF13894.6 GAM28995.1 - 2.4e-05 24.8 4.7 0.0071 17.1 0.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAM28995.1 - 0.00017 21.9 4.6 0.026 15.0 0.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GAM28995.1 - 0.00049 20.3 6.4 0.13 12.6 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Ima1_N PF09779.9 GAM28995.1 - 0.087 13.7 0.1 0.087 13.7 0.1 1.7 2 1 0 2 2 2 0 Ima1 N-terminal domain zf-BED PF02892.15 GAM28995.1 - 2 8.5 6.6 17 5.5 3.3 2.6 1 1 1 2 2 2 0 BED zinc finger ABC1 PF03109.16 GAM28996.1 - 1.3e-27 96.3 0.1 5.5e-27 94.3 0.0 2.1 2 0 0 2 2 2 1 ABC1 family DUF4834 PF16118.5 GAM28996.1 - 0.099 13.6 2.1 0.25 12.3 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) APH PF01636.23 GAM28996.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1682 PF07946.14 GAM28996.1 - 0.12 11.5 7.3 0.21 10.7 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Neur_chan_memb PF02932.16 GAM28996.1 - 0.21 11.6 1.5 0.32 11.0 1.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 GAM28996.1 - 0.48 9.4 1.8 0.69 8.9 1.8 1.2 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 GAM28996.1 - 2.4 6.8 7.7 3.3 6.4 7.7 1.2 1 0 0 1 1 1 0 Presenilin RasGEF PF00617.19 GAM28997.1 - 4.6e-61 206.1 6.4 5.3e-61 205.9 3.9 2.4 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM28997.1 - 1.6e-20 73.3 0.5 1.6e-20 73.3 0.5 2.4 3 0 0 3 3 3 1 RasGEF N-terminal motif CH PF00307.31 GAM28997.1 - 1.4e-12 47.8 0.4 1.4e-12 47.8 0.4 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain CDC24 PF06395.11 GAM28997.1 - 0.0018 18.5 4.9 0.0024 18.1 0.0 3.0 3 0 0 3 3 3 1 CDC24 Calponin WPP PF13943.6 GAM28997.1 - 0.079 13.4 0.2 0.29 11.6 0.2 2.0 1 0 0 1 1 1 0 WPP domain SKA2 PF16740.5 GAM28997.1 - 1.5 8.6 6.9 4.2 7.2 1.8 3.4 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 LRR_6 PF13516.6 GAM28998.1 - 1.6e-11 43.3 18.4 0.14 12.3 0.1 9.2 9 0 0 9 9 9 4 Leucine Rich repeat LRR_8 PF13855.6 GAM28998.1 - 5.1e-11 42.2 15.1 0.0012 18.5 0.1 5.9 4 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 GAM28998.1 - 2.5e-10 40.4 31.7 0.0003 21.1 0.1 7.4 4 3 6 10 10 10 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM28998.1 - 0.001 19.3 29.6 6.3 7.8 0.1 9.3 11 1 0 11 11 11 3 Leucine Rich Repeat Pentapeptide_4 PF13599.6 GAM28998.1 - 0.042 14.0 0.3 4.2 7.6 0.0 3.5 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) Ank_2 PF12796.7 GAM28999.1 - 1.1e-31 109.3 7.8 6.1e-07 29.9 0.1 6.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM28999.1 - 7.8e-31 106.1 12.2 3.2e-05 24.4 0.1 10.4 5 2 7 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAM28999.1 - 1.1e-23 83.0 14.0 0.0057 16.9 0.2 12.4 2 2 12 14 14 14 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM28999.1 - 1.4e-17 61.9 1.2 0.29 11.8 0.0 11.6 13 0 0 13 13 13 2 Ankyrin repeat Ank PF00023.30 GAM28999.1 - 1.8e-05 24.9 1.0 65 4.2 0.1 7.6 4 3 1 6 6 6 0 Ankyrin repeat DUF5049 PF16468.5 GAM28999.1 - 4.2e-05 23.4 1.8 1.6 8.7 0.0 6.7 6 1 3 9 9 9 1 Domain of unknown function (DUF5049) DUF1843 PF08898.10 GAM28999.1 - 0.043 14.3 0.4 29 5.3 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) Rbsn PF11464.8 GAM28999.1 - 0.15 11.8 0.4 16 5.4 0.0 3.3 3 0 0 3 3 3 0 Rabenosyn Rab binding domain ENTH PF01417.20 GAM28999.1 - 0.16 12.0 0.1 9.8 6.2 0.0 3.4 4 0 0 4 4 4 0 ENTH domain DUF1707 PF08044.11 GAM28999.1 - 0.25 11.4 1.9 23 5.2 0.0 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF1707) AAA PF00004.29 GAM29000.1 - 1.1e-80 268.6 0.0 2.2e-41 141.4 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM29000.1 - 7.7e-30 102.5 0.4 1.5e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 GAM29000.1 - 1.3e-14 54.7 0.0 1.1e-08 35.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAM29000.1 - 1.1e-12 48.7 0.3 0.00049 20.5 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 GAM29000.1 - 7.6e-10 38.9 0.1 0.0019 18.2 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAM29000.1 - 1.9e-07 31.4 2.0 0.027 14.8 0.2 4.2 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.12 GAM29000.1 - 3.3e-07 30.2 0.1 0.00089 19.0 0.0 3.2 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAM29000.1 - 6.1e-07 29.7 0.0 0.0074 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAM29000.1 - 1.8e-06 28.0 0.0 0.046 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 GAM29000.1 - 4e-06 26.3 0.0 0.0051 16.1 0.0 2.6 3 0 0 3 3 2 2 TIP49 P-loop domain TsaE PF02367.17 GAM29000.1 - 5.1e-06 26.5 0.1 0.035 14.1 0.0 2.7 2 1 1 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 GAM29000.1 - 7.3e-06 25.9 0.0 0.062 13.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAM29000.1 - 1.2e-05 25.6 0.1 0.34 11.3 0.0 3.1 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.12 GAM29000.1 - 1.8e-05 24.8 0.5 0.3 11.0 0.0 3.5 3 0 0 3 3 3 2 NACHT domain AAA_11 PF13086.6 GAM29000.1 - 3.2e-05 23.8 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 GAM29000.1 - 6e-05 23.6 0.1 0.58 10.7 0.0 3.0 2 1 0 2 2 2 2 ABC transporter Viral_helicase1 PF01443.18 GAM29000.1 - 6.5e-05 22.8 0.0 0.054 13.2 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 GAM29000.1 - 8.2e-05 22.6 0.1 0.0026 17.7 0.0 2.7 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_7 PF12775.7 GAM29000.1 - 0.00012 21.7 0.0 0.14 11.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 GAM29000.1 - 0.00014 21.1 0.0 0.14 11.3 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF815) MCM PF00493.23 GAM29000.1 - 0.00042 19.5 0.0 0.66 9.0 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain AAA_24 PF13479.6 GAM29000.1 - 0.001 18.8 0.0 0.036 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAM29000.1 - 0.002 17.9 0.0 0.81 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 GAM29000.1 - 0.0021 18.0 0.5 0.87 9.5 0.0 3.0 3 0 0 3 3 2 1 NTPase Zeta_toxin PF06414.12 GAM29000.1 - 0.0025 17.1 0.0 0.38 10.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 GAM29000.1 - 0.0026 17.5 0.2 0.97 9.1 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.6 GAM29000.1 - 0.003 17.9 0.6 0.54 10.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAM29000.1 - 0.0031 18.0 0.1 4 8.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain Bac_DnaA PF00308.18 GAM29000.1 - 0.0056 16.5 0.0 0.56 10.0 0.0 2.5 2 1 0 2 2 2 1 Bacterial dnaA protein ATPase_2 PF01637.18 GAM29000.1 - 0.0077 16.2 0.0 1.8 8.5 0.0 3.6 3 2 2 5 5 5 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 GAM29000.1 - 0.011 15.1 0.8 5 6.4 0.1 2.8 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAM29000.1 - 0.012 15.8 0.2 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAM29000.1 - 0.033 13.9 0.1 2.5 7.8 0.0 3.4 2 2 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 GAM29000.1 - 0.042 13.6 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AFG1_ATPase PF03969.16 GAM29000.1 - 0.043 12.7 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase cobW PF02492.19 GAM29000.1 - 0.049 13.2 0.2 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 GAM29000.1 - 0.055 12.6 0.0 0.48 9.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Hydin_ADK PF17213.3 GAM29000.1 - 0.056 13.7 0.4 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_25 PF13481.6 GAM29000.1 - 0.089 12.4 0.6 11 5.5 0.0 3.3 3 1 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 GAM29000.1 - 0.11 12.2 0.0 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 GAM29000.1 - 0.27 10.6 0.9 17 4.6 0.1 3.2 3 1 1 4 4 4 0 KaiC zf-ribbon_3 PF13248.6 GAM29001.1 - 0.0067 15.8 2.3 0.013 14.9 2.3 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 GAM29001.1 - 6.2 6.7 10.0 7 6.5 6.9 2.6 1 1 1 2 2 2 0 zinc-ribbon domain Ribosomal_L27 PF01016.19 GAM29002.1 - 7.4e-36 122.0 1.0 1e-35 121.6 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein NAGPA PF09992.9 GAM29002.1 - 0.02 15.1 0.6 0.7 10.1 0.1 2.1 1 1 1 2 2 2 0 Phosphodiester glycosidase GST_N PF02798.20 GAM29003.1 - 1.4e-11 44.6 0.0 2.5e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM29003.1 - 1e-10 41.7 0.1 1.7e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM29003.1 - 1.5e-09 38.0 0.3 4.1e-09 36.5 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM29003.1 - 4.3e-08 33.4 0.0 7.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM29003.1 - 4.9e-08 33.2 0.0 9.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM29003.1 - 2e-07 30.9 0.4 6.1e-07 29.4 0.3 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PH PF00169.29 GAM29004.1 - 6.8e-12 45.8 0.0 6.9e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 PH domain Ank_4 PF13637.6 GAM29004.1 - 2.1e-11 44.1 0.0 8.7e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM29004.1 - 2.8e-09 37.5 0.2 2.5e-05 24.8 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM29004.1 - 1.4e-08 34.3 0.1 0.014 15.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAM29004.1 - 9.4e-08 32.2 0.2 0.00018 21.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAM29004.1 - 2.4e-06 27.7 0.0 0.016 15.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat DUF3447 PF11929.8 GAM29004.1 - 0.056 13.4 2.3 0.067 13.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) WD40 PF00400.32 GAM29005.1 - 8e-05 23.3 16.5 0.097 13.6 1.4 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat PHTB1_N PF14727.6 GAM29005.1 - 0.079 12.3 0.0 1.1 8.5 0.0 2.4 3 0 0 3 3 3 0 PTHB1 N-terminus Acyl-CoA_dh_M PF02770.19 GAM29006.1 - 1.3e-15 57.3 0.0 2.6e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 GAM29006.1 - 1.1e-09 38.7 0.1 2e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 GAM29006.1 - 1.1e-09 38.1 0.0 2.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Sybindin PF04099.12 GAM29007.1 - 5e-41 140.0 1.5 5.6e-41 139.8 1.5 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 GAM29007.1 - 4e-06 27.0 0.5 4.4e-06 26.8 0.5 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region DUF4821 PF16092.5 GAM29007.1 - 0.058 13.0 0.3 0.071 12.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4821) zf-C3HC4_3 PF13920.6 GAM29008.1 - 9.3e-12 44.6 6.5 1.5e-11 43.9 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM29008.1 - 2.1e-10 40.8 10.0 3.8e-10 39.9 10.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAM29008.1 - 1.2e-09 37.8 9.8 2.3e-09 37.0 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM29008.1 - 4.9e-09 35.9 9.4 8.9e-09 35.1 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAM29008.1 - 1.3e-08 35.0 5.8 3.5e-08 33.6 5.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAM29008.1 - 2.8e-08 33.7 5.7 5.8e-08 32.6 5.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAM29008.1 - 5.9e-08 32.5 6.6 1.1e-07 31.6 6.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAM29008.1 - 5.2e-07 29.5 7.6 8.7e-07 28.8 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAM29008.1 - 6.5e-05 23.0 9.6 0.00012 22.1 9.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAM29008.1 - 0.0024 17.7 3.6 0.0045 16.8 3.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 GAM29008.1 - 0.0061 16.2 6.9 0.014 15.0 6.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAM29008.1 - 0.0064 16.5 5.5 0.068 13.2 4.7 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 GAM29008.1 - 0.069 13.3 5.0 0.16 12.1 5.0 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 GAM29008.1 - 0.12 12.2 4.1 0.24 11.2 4.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SelP_N PF04592.14 GAM29008.1 - 0.19 11.1 8.6 0.35 10.2 8.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Nicastrin PF05450.15 GAM29008.1 - 0.34 10.3 6.1 0.1 12.1 3.2 1.6 2 0 0 2 2 2 0 Nicastrin zf-RING_4 PF14570.6 GAM29008.1 - 0.4 10.5 7.5 1.2 9.0 7.5 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 GAM29008.1 - 1.1 9.1 6.0 2.4 8.0 6.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-P11 PF03854.14 GAM29008.1 - 1.2 8.9 4.7 17 5.2 5.4 2.2 1 1 1 2 2 2 0 P-11 zinc finger Nitrate_red_gam PF02665.14 GAM29009.1 - 0.0058 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Nitrate reductase gamma subunit ECF_trnsprt PF12822.7 GAM29009.1 - 0.014 15.5 0.1 0.046 13.8 0.0 2.0 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Chlam_PMP PF02415.17 GAM29009.1 - 0.5 11.0 0.1 0.5 11.0 0.1 7.4 9 1 0 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Serinc PF03348.15 GAM29010.1 - 3e-104 349.3 8.3 3.4e-104 349.2 8.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2157 PF09925.9 GAM29010.1 - 0.0035 17.2 4.2 0.0035 17.2 4.2 2.7 2 1 1 3 3 3 1 Predicted membrane protein (DUF2157) DUF3535 PF12054.8 GAM29011.1 - 4e-77 260.3 2.2 4e-77 260.3 2.2 3.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 GAM29011.1 - 2.8e-61 207.2 0.0 1.1e-60 205.2 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAM29011.1 - 5.4e-17 62.1 0.0 3.1e-16 59.7 0.0 2.4 2 0 0 2 2 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 GAM29011.1 - 2e-11 43.1 3.6 0.6 10.5 0.0 9.6 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 GAM29011.1 - 2.3e-11 43.9 0.4 0.0049 17.2 0.1 5.6 4 1 0 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 GAM29011.1 - 4.4e-09 36.8 0.2 0.0015 19.1 0.0 4.1 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 GAM29011.1 - 1.9e-08 34.6 5.3 0.00016 22.1 0.0 6.4 6 1 1 7 7 7 1 HEAT-like repeat ResIII PF04851.15 GAM29011.1 - 9.4e-06 25.7 0.0 4.3e-05 23.6 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cnd1 PF12717.7 GAM29011.1 - 0.0018 18.4 3.2 0.64 10.0 0.1 4.5 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF1804 PF08822.11 GAM29011.1 - 0.039 13.9 0.2 7.4 6.5 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) DUF3385 PF11865.8 GAM29011.1 - 0.27 11.2 6.4 8.1 6.3 0.1 4.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3385) SPT6_acidic PF14632.6 GAM29011.1 - 1.3 9.7 8.3 3.4 8.3 2.2 2.7 2 0 0 2 2 2 0 Acidic N-terminal SPT6 PRC2_HTH_1 PF18118.1 GAM29011.1 - 4.3 8.2 6.5 1.1 10.2 0.5 2.8 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain ATP11 PF06644.11 GAM29011.1 - 8.7 6.0 9.2 0.42 10.3 3.1 1.9 2 0 0 2 2 2 0 ATP11 protein PBP1_TM PF14812.6 GAM29011.1 - 9.2 6.7 9.9 0.59 10.5 2.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S9_N PF02897.15 GAM29013.1 - 2.3e-103 346.2 1.7 2.9e-103 345.9 1.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 GAM29013.1 - 8.1e-62 208.5 0.4 1.8e-61 207.3 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAM29013.1 - 0.013 15.1 0.3 0.46 10.1 0.0 2.9 2 1 1 3 3 3 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM29013.1 - 0.099 11.9 0.0 0.59 9.3 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 2OG-FeII_Oxy_3 PF13640.6 GAM29014.1 - 1.4e-10 41.9 0.0 2.5e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 GAM29014.1 - 0.021 13.9 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein EMG1 PF03587.14 GAM29015.1 - 4.4e-90 300.6 0.0 6.1e-90 300.1 0.0 1.2 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase ETX_MTX2 PF03318.13 GAM29015.1 - 0.0059 16.4 1.8 0.0093 15.8 1.8 1.3 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Pro_isomerase PF00160.21 GAM29016.1 - 1.3e-49 168.6 0.2 1.4e-49 168.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3439 PF11921.8 GAM29017.1 - 0.29 11.1 17.9 1.9 8.5 2.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) V-ATPase_H_N PF03224.14 GAM29018.1 - 3e-58 197.6 0.2 7.3e-58 196.3 0.1 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 GAM29018.1 - 9.4e-43 145.1 4.5 1.2e-42 144.7 1.1 2.5 3 0 0 3 3 3 1 V-ATPase subunit H Arm_2 PF04826.13 GAM29018.1 - 7.1e-05 22.4 0.5 0.00059 19.4 0.1 2.2 2 0 0 2 2 2 1 Armadillo-like Cnd1 PF12717.7 GAM29018.1 - 0.042 13.9 0.4 22 5.1 0.0 3.3 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Nrap_D5 PF17406.2 GAM29018.1 - 0.052 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Arm PF00514.23 GAM29018.1 - 0.1 12.7 0.1 16 5.7 0.0 3.7 3 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat SWIM PF04434.17 GAM29020.1 - 0.0014 18.3 0.2 0.0034 17.0 0.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger SR-25 PF10500.9 GAM29020.1 - 3.8 7.0 15.9 1.8 8.1 12.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dicty_REP PF05086.12 GAM29020.1 - 4.5 5.1 23.0 3 5.7 8.5 2.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein RhoGAP PF00620.27 GAM29021.1 - 5e-29 101.1 0.3 4e-27 94.9 0.1 2.2 2 0 0 2 2 2 2 RhoGAP domain zf-CCCH_2 PF14608.6 GAM29022.1 - 0.23 12.0 0.4 0.23 12.0 0.4 6.2 6 2 0 6 6 6 0 RNA-binding, Nab2-type zinc finger p450 PF00067.22 GAM29023.1 - 3.4e-67 227.2 0.0 4.2e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RsmF_methylt_CI PF17126.5 GAM29023.1 - 0.0087 16.1 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 RsmF rRNA methyltransferase first C-terminal domain Presenilin PF01080.17 GAM29023.1 - 0.39 9.4 1.2 0.53 9.0 1.2 1.1 1 0 0 1 1 1 0 Presenilin zf-RING_UBOX PF13445.6 GAM29024.1 - 3.6e-13 49.3 12.2 1.4e-08 34.6 0.7 2.7 2 1 0 2 2 2 2 RING-type zinc-finger Rtf2 PF04641.12 GAM29024.1 - 9.8e-12 44.8 13.8 2.8e-10 40.0 3.9 2.2 2 0 0 2 2 2 2 Rtf2 RING-finger zf-NOSIP PF15906.5 GAM29024.1 - 7e-11 42.1 0.8 1.6e-10 41.0 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 GAM29024.1 - 5.6e-09 36.2 21.1 1.9e-05 24.9 8.6 3.1 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.6 GAM29024.1 - 3.3e-07 30.3 20.9 2.8e-05 24.2 3.3 2.9 3 1 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAM29024.1 - 4.8e-07 29.5 27.5 4.4e-06 26.4 6.2 3.5 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAM29024.1 - 5.6e-06 26.1 23.7 3.9e-05 23.4 5.2 3.3 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 GAM29024.1 - 0.012 15.7 9.8 0.012 15.7 9.8 2.7 2 1 0 2 2 2 0 FYVE zinc finger zf-RING_5 PF14634.6 GAM29024.1 - 0.014 15.3 13.3 0.014 15.3 13.3 4.3 2 2 3 5 5 5 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GAM29024.1 - 0.018 14.9 2.9 0.018 14.9 2.9 4.1 2 2 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GAM29024.1 - 0.2 11.8 20.9 1.8 8.7 9.3 3.0 2 1 0 2 2 2 0 zinc RING finger of MSL2 zf-FLZ PF04570.14 GAM29024.1 - 0.21 11.1 0.1 0.21 11.1 0.1 3.3 2 1 1 3 3 3 0 zinc-finger of the FCS-type, C2-C2 zf-Nse PF11789.8 GAM29024.1 - 0.22 11.4 6.7 0.58 10.0 1.7 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 GAM29024.1 - 0.29 11.0 10.6 0.17 11.8 0.5 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 GAM29024.1 - 7.1 7.0 14.5 3.2 8.2 0.5 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Spec3 PF15795.5 GAM29025.1 - 1.8e-08 34.8 18.4 0.00091 19.7 10.7 2.1 1 1 1 2 2 2 2 Ectodermal ciliogenesis protein DUF3040 PF11239.8 GAM29025.1 - 3.6 7.9 4.6 8.3 6.8 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) EGF_2 PF07974.13 GAM29027.1 - 1.7e-05 25.1 13.5 3.3e-05 24.1 13.5 1.5 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 GAM29027.1 - 0.00081 19.6 6.1 0.0016 18.7 6.1 1.5 1 0 0 1 1 1 1 EGF-like domain Pkinase_Tyr PF07714.17 GAM29028.1 - 1.1e-52 178.8 0.0 1.7e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM29028.1 - 2.2e-50 171.5 0.0 4.5e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 GAM29028.1 - 0.002 17.5 0.0 0.0051 16.2 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.13 GAM29028.1 - 0.16 12.0 11.4 0.28 11.1 11.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 GAM29030.1 - 1.3e-35 123.2 11.9 1.3e-35 123.2 11.9 1.7 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC_2 PF13515.6 GAM29030.1 - 4.6e-17 62.3 16.3 4.6e-17 62.3 16.3 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 GAM29030.1 - 7.8e-16 57.8 7.5 7.8e-16 57.8 7.5 2.0 2 0 0 2 2 2 1 Fusaric acid resistance protein family NDUF_B12 PF08122.12 GAM29031.1 - 1.9e-06 27.8 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Alba PF01918.21 GAM29032.1 - 4.5e-06 26.4 0.3 8.8e-06 25.4 0.3 1.6 1 0 0 1 1 1 1 Alba UbiA PF01040.18 GAM29033.1 - 2.9e-52 177.5 17.2 4.3e-52 176.9 17.2 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family PARP PF00644.20 GAM29034.1 - 3.1e-13 49.8 3.6 1.2e-11 44.5 3.6 3.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain CxC6 PF18721.1 GAM29034.1 - 0.0011 19.2 13.8 1.4 9.3 0.2 4.8 5 0 0 5 5 5 3 CxC6 like cysteine cluster associated with KDZ transposases zf-C3Hc3H PF13891.6 GAM29034.1 - 0.043 14.2 15.8 1.2 9.6 0.4 4.6 3 1 0 4 4 4 0 Potential DNA-binding domain WRC PF08879.10 GAM29034.1 - 9 6.1 10.0 21 4.9 0.1 4.4 5 0 0 5 5 5 0 WRC Herpes_gI PF01688.17 GAM29034.1 - 9.9 6.1 12.9 2.3 8.1 0.7 3.6 1 1 3 4 4 4 0 Alphaherpesvirus glycoprotein I DUF1768 PF08719.11 GAM29035.1 - 1.4e-33 116.4 0.1 2.2e-33 115.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) HAT PF02184.16 GAM29035.1 - 0.07 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat CxC6 PF18721.1 GAM29036.1 - 1.8e-05 24.9 39.7 0.35 11.2 0.7 7.7 7 1 0 7 7 7 6 CxC6 like cysteine cluster associated with KDZ transposases DUF728 PF05304.12 GAM29036.1 - 0.017 15.0 13.8 0.7 9.7 0.3 5.2 5 1 1 6 6 6 0 Protein of unknown function (DUF728) Oxidored-like PF09791.9 GAM29036.1 - 0.4 10.4 11.3 1.3 8.8 0.1 4.4 4 0 0 4 4 4 0 Oxidoreductase-like protein, N-terminal SLS PF14611.6 GAM29036.1 - 0.86 9.4 3.5 0.3 10.9 0.4 1.8 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator PARP PF00644.20 GAM29037.1 - 9.9e-08 31.8 0.0 1.1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PTS_2-RNA PF01885.16 GAM29037.1 - 0.094 12.8 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Exotox-A_cataly PF09009.10 GAM29037.1 - 0.1 12.3 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Exotoxin A catalytic Ndc1_Nup PF09531.10 GAM29038.1 - 2.1 6.9 7.9 2.2 6.9 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup bZIP_1 PF00170.21 GAM29039.1 - 3.9e-12 46.1 6.1 1e-11 44.8 6.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAM29039.1 - 1.5e-11 44.1 2.2 1.5e-11 44.1 2.2 2.8 3 0 0 3 3 3 2 Basic region leucine zipper Shugoshin_N PF07558.11 GAM29039.1 - 0.0088 15.9 0.1 0.032 14.1 0.1 2.0 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region bZIP_Maf PF03131.17 GAM29039.1 - 0.013 16.0 6.6 0.013 16.0 6.6 2.9 2 1 1 3 3 3 0 bZIP Maf transcription factor DUF2624 PF11116.8 GAM29039.1 - 0.035 15.0 0.3 0.12 13.2 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) JIP_LZII PF16471.5 GAM29039.1 - 1.3 9.3 5.4 0.33 11.2 1.2 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II TMCO5 PF14992.6 GAM29039.1 - 2.9 7.4 16.2 0.021 14.4 6.9 2.1 2 1 0 2 2 2 0 TMCO5 family Adap_comp_sub PF00928.21 GAM29040.1 - 2.1e-74 250.2 0.6 2.5e-74 250.0 0.6 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAM29040.1 - 0.00064 19.7 0.2 0.0014 18.5 0.2 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.10 GAM29041.1 - 1.1e-58 198.2 1.7 1.9e-58 197.5 1.7 1.3 1 0 0 1 1 1 1 Maf1 regulator PCNA_N PF00705.18 GAM29041.1 - 0.047 13.4 0.7 0.17 11.6 0.3 2.0 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain RabGAP-TBC PF00566.18 GAM29042.1 - 1.7e-45 155.3 0.3 4.5e-45 154.0 0.3 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRP36 PF06102.12 GAM29042.1 - 0.099 12.6 8.5 0.15 12.0 8.5 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 FinO_N PF12602.8 GAM29042.1 - 0.15 12.4 1.1 0.6 10.5 0.7 2.1 2 0 0 2 2 2 0 Fertility inhibition protein N terminal FNIP PF05725.12 GAM29044.1 - 2.1e-48 162.2 11.2 2.9e-13 49.7 0.1 8.1 4 3 2 8 8 8 7 FNIP Repeat HPS6 PF15702.5 GAM29045.1 - 4.5e-09 34.9 0.9 1.1e-06 27.0 0.6 2.1 2 0 0 2 2 2 2 Hermansky-Pudlak syndrome 6 protein Spt20 PF12090.8 GAM29045.1 - 0.04 13.5 14.8 0.28 10.8 2.6 2.5 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 GAM29045.1 - 0.063 13.3 21.8 0.042 13.9 3.3 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 EMP24_GP25L PF01105.24 GAM29046.1 - 3.9e-56 189.9 0.0 4.5e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 GAM29046.1 - 0.00029 21.0 0.0 0.00053 20.2 0.0 1.4 1 0 0 1 1 1 1 SdrD B-like domain DUF3539 PF12058.8 GAM29046.1 - 0.026 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) CarboxypepD_reg PF13620.6 GAM29046.1 - 0.096 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain G-patch PF01585.23 GAM29047.1 - 4.5e-12 45.6 2.6 1.2e-11 44.2 2.6 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAM29047.1 - 0.00039 20.5 1.9 0.00039 20.5 1.9 3.6 4 0 0 4 4 4 1 G-patch domain S4 PF01479.25 GAM29049.1 - 1.9e-06 27.5 0.0 4.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 GAM29049.1 - 0.025 15.5 0.9 0.054 14.4 0.7 1.8 2 1 0 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain Ank_5 PF13857.6 GAM29050.1 - 7.3e-11 42.1 0.1 1.3e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM29050.1 - 4.9e-07 30.2 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM29050.1 - 6.4e-07 29.8 0.1 1.6e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM29050.1 - 4.8e-05 23.4 0.2 0.00034 20.8 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 GAM29050.1 - 9.1e-05 22.7 0.1 0.00023 21.5 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat DUF3464 PF11947.8 GAM29050.1 - 0.12 12.1 1.2 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 GST_N PF02798.20 GAM29051.1 - 5.2e-12 45.9 0.0 1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM29051.1 - 8.5e-12 45.1 0.1 1.7e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAM29051.1 - 2.9e-10 40.4 0.0 6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAM29051.1 - 9.7e-09 35.4 0.0 2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAM29051.1 - 1.1e-08 35.0 0.9 2e-08 34.1 0.4 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAM29051.1 - 1.8e-07 31.3 0.1 3.3e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4007 PF13182.6 GAM29051.1 - 0.063 12.4 0.3 0.073 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) KRTDAP PF15200.6 GAM29051.1 - 0.93 9.3 7.9 2.4 8.0 0.1 2.9 3 0 0 3 3 3 0 Keratinocyte differentiation-associated Exo_endo_phos PF03372.23 GAM29053.1 - 0.0011 18.6 0.0 0.0054 16.3 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M8 PF01457.16 GAM29054.1 - 2.9e-59 201.2 3.9 3.9e-59 200.7 3.9 1.1 1 0 0 1 1 1 1 Leishmanolysin UQ_con PF00179.26 GAM29055.1 - 9e-34 116.1 0.4 2.8e-27 95.1 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 GAM29055.1 - 7.4e-06 26.2 0.6 0.016 15.5 0.0 3.1 2 1 0 2 2 2 2 RWD domain UEV PF05743.13 GAM29055.1 - 0.00059 19.7 0.2 0.0042 16.9 0.0 2.5 2 1 0 2 2 2 1 UEV domain Cwf_Cwc_15 PF04889.12 GAM29055.1 - 0.38 10.4 10.7 0.7 9.6 10.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DBC1 PF14443.6 GAM29056.1 - 1.2e-35 122.2 0.0 1.2e-35 122.2 0.0 2.3 2 0 0 2 2 2 1 DBC1 Spt20 PF12090.8 GAM29056.1 - 0.0003 20.5 11.1 0.0003 20.5 11.1 4.0 5 0 0 5 5 5 2 Spt20 family Maf1 PF09174.10 GAM29056.1 - 1.4 9.1 18.8 0.11 12.6 0.7 3.1 3 1 0 3 3 3 0 Maf1 regulator IP_trans PF02121.18 GAM29057.1 - 8.8e-111 369.4 1.1 1e-110 369.1 1.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Elf1 PF05129.13 GAM29057.1 - 0.07 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like MATH PF00917.26 GAM29058.1 - 6.1e-43 145.6 13.3 2.9e-16 59.6 0.4 4.5 4 0 0 4 4 4 4 MATH domain DUF2722 PF10846.8 GAM29058.1 - 1.9e-05 23.9 9.3 2.9e-05 23.2 9.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) EPL1 PF10513.9 GAM29058.1 - 0.0048 17.3 2.4 0.015 15.7 2.4 1.8 1 0 0 1 1 1 1 Enhancer of polycomb-like CDK2AP PF09806.9 GAM29058.1 - 0.046 13.8 10.1 0.077 13.0 10.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein TFIIA PF03153.13 GAM29058.1 - 0.4 10.6 22.1 0.64 10.0 22.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GRP PF07172.11 GAM29058.1 - 0.44 11.3 18.9 0.86 10.3 18.9 1.4 1 0 0 1 1 1 0 Glycine rich protein family AF-4 PF05110.13 GAM29058.1 - 0.47 8.5 9.7 0.69 7.9 9.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Presenilin PF01080.17 GAM29058.1 - 0.69 8.6 3.3 1 8.0 3.3 1.2 1 0 0 1 1 1 0 Presenilin Med15 PF09606.10 GAM29058.1 - 9 4.8 27.1 13 4.4 27.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PIG-S PF10510.9 GAM29059.1 - 8.8e-103 344.9 15.6 3.1e-97 326.6 9.3 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein ATP-gua_PtransN PF02807.15 GAM29059.1 - 0.0087 16.4 0.2 1.2 9.6 0.1 2.7 2 1 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain Phage_int_SAM_1 PF02899.17 GAM29059.1 - 0.14 12.5 0.9 0.41 11.0 0.1 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain VASP_tetra PF08776.11 GAM29060.1 - 0.082 12.5 13.3 0.41 10.3 13.3 2.0 1 1 0 1 1 1 0 VASP tetramerisation domain DUF737 PF05300.11 GAM29060.1 - 4.8 7.5 15.9 0.59 10.5 5.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Pkinase_Tyr PF07714.17 GAM29061.1 - 1.5e-52 178.4 0.0 3.5e-52 177.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM29061.1 - 4.3e-49 167.3 0.0 1e-48 166.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 GAM29061.1 - 5e-25 87.9 4.9 1.7e-09 38.1 0.5 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM29061.1 - 3.4e-22 78.5 1.8 2.7e-08 34.2 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM29061.1 - 5.6e-22 77.2 1.0 1.9e-05 24.9 0.0 6.0 6 0 0 6 6 5 4 Ankyrin repeat GRAM PF02893.20 GAM29061.1 - 9.3e-21 73.8 0.2 1.9e-20 72.8 0.2 1.6 1 0 0 1 1 1 1 GRAM domain Ank_3 PF13606.6 GAM29061.1 - 3e-17 60.9 2.2 0.0014 18.9 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 GAM29061.1 - 4.1e-17 62.0 1.0 0.00014 22.0 0.1 4.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) C1_1 PF00130.22 GAM29061.1 - 4.1e-09 36.2 8.8 9.6e-09 35.0 8.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 GAM29061.1 - 0.016 15.1 5.1 0.042 13.8 5.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PH PF00169.29 GAM29061.1 - 0.099 13.2 0.2 0.41 11.2 0.0 2.1 2 0 0 2 2 1 0 PH domain APH PF01636.23 GAM29061.1 - 0.17 11.8 0.0 1.2 9.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family PHD PF00628.29 GAM29061.1 - 1.8 8.5 5.6 5.4 7.0 5.6 1.8 1 0 0 1 1 1 0 PHD-finger RasGEF PF00617.19 GAM29062.1 - 4.3e-43 147.6 1.8 1.4e-42 145.9 1.8 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAM29062.1 - 3.1e-18 65.9 1.7 1.8e-17 63.5 1.7 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif EntA_Immun PF08951.10 GAM29062.1 - 0.0044 17.4 1.3 0.0044 17.4 1.3 3.1 2 0 0 2 2 2 1 Enterocin A Immunity Rpr2 PF04032.16 GAM29062.1 - 0.012 15.8 0.9 0.075 13.3 1.0 2.3 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain PUF PF00806.19 GAM29063.1 - 3.9e-31 105.0 16.2 5e-05 22.8 0.2 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 GAM29063.1 - 1.4e-05 25.5 0.1 0.029 14.7 0.0 3.6 2 1 1 3 3 3 2 CPL (NUC119) domain MetJ PF01340.20 GAM29063.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 Met Apo-repressor, MetJ Cupin_8 PF13621.6 GAM29066.1 - 6.1e-08 32.7 0.0 9.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain WD40 PF00400.32 GAM29067.1 - 4.7e-12 46.2 15.9 0.00039 21.2 0.3 8.3 8 0 0 8 8 8 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 GAM29067.1 - 3e-11 42.8 14.9 3e-11 42.8 14.9 2.1 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 GAM29067.1 - 1.1e-05 25.6 6.8 1.1e-05 25.6 6.8 4.0 2 1 1 3 3 3 1 Zinc-ribbon like family zf-C3HC4_2 PF13923.6 GAM29067.1 - 0.062 13.2 3.3 0.25 11.2 3.3 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RWD PF05773.22 GAM29067.1 - 0.5 10.7 6.0 2.8 8.3 6.0 2.3 1 1 0 1 1 1 0 RWD domain DZR PF12773.7 GAM29067.1 - 1.2 9.2 7.7 5.7 7.1 8.0 2.0 1 1 1 2 2 2 0 Double zinc ribbon TFIIA PF03153.13 GAM29067.1 - 3.8 7.4 20.5 0.39 10.7 2.8 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF908 PF06012.12 GAM29068.1 - 0.2 11.0 7.5 0.29 10.5 7.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF515 PF04415.12 GAM29068.1 - 0.94 7.8 20.4 1.4 7.2 20.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Mucin PF01456.17 GAM29068.1 - 6.6 6.7 49.6 0.42 10.6 41.3 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Glyco_transf_49 PF13896.6 GAM29069.1 - 4e-50 171.0 0.4 7.7e-41 140.5 0.3 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAM29069.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 DSPc PF00782.20 GAM29070.1 - 5.2e-18 65.2 0.0 6.3e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 GAM29070.1 - 0.0013 18.8 0.0 0.0044 17.1 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 GAM29070.1 - 0.0016 18.0 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAM29070.1 - 0.0044 17.0 0.0 0.0065 16.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 GAM29070.1 - 0.02 15.2 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain CDKN3 PF05706.12 GAM29070.1 - 0.023 14.4 0.2 0.037 13.7 0.0 1.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Glyco_transf_10 PF00852.19 GAM29071.1 - 1.4e-34 119.4 2.1 1.4e-34 119.4 0.8 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 GAM29071.1 - 0.007 16.8 0.0 0.029 14.8 0.0 2.1 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal YARHG PF13308.6 GAM29071.1 - 0.035 14.0 0.3 0.077 12.9 0.3 1.5 1 0 0 1 1 1 0 YARHG domain Glyco_transf_10 PF00852.19 GAM29072.1 - 2.8e-38 131.4 1.2 5.6e-38 130.4 1.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 GAM29072.1 - 0.0017 18.8 0.0 0.0038 17.6 0.0 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Ras PF00071.22 GAM29074.1 - 3e-57 192.7 0.8 3.5e-57 192.5 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM29074.1 - 3e-35 121.0 0.2 4.7e-35 120.4 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM29074.1 - 1.1e-20 73.8 0.3 1.3e-20 73.5 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM29074.1 - 1.3e-06 28.0 0.2 1.6e-06 27.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAM29074.1 - 1.6e-05 24.5 1.0 4.8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAM29074.1 - 1.8e-05 24.4 0.2 0.0014 18.3 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 GAM29074.1 - 0.0013 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein MMR_HSR1 PF01926.23 GAM29074.1 - 0.0016 18.5 0.1 0.0029 17.7 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 GAM29074.1 - 0.0044 16.8 0.1 0.0089 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 GAM29074.1 - 0.0059 16.4 0.1 0.069 12.9 0.1 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 GAM29074.1 - 0.01 15.7 0.2 5.4 6.9 0.0 2.6 1 1 2 3 3 3 0 RsgA GTPase G-alpha PF00503.20 GAM29074.1 - 0.011 15.0 0.1 0.24 10.5 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 GAM29074.1 - 0.035 13.6 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region YwhD PF08741.10 GAM29074.1 - 0.056 13.1 0.1 0.088 12.5 0.1 1.3 1 0 0 1 1 1 0 YwhD family AAA PF00004.29 GAM29074.1 - 0.073 13.5 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAM29074.1 - 0.17 12.3 0.0 0.24 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Acyltransferase PF01553.21 GAM29075.1 - 1.1e-20 73.6 0.0 1.7e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase RNase_P_Rpp14 PF01900.19 GAM29076.1 - 4.8e-17 62.1 0.0 6.3e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family DCP1 PF06058.13 GAM29077.1 - 2.6e-39 133.8 2.0 4.1e-39 133.1 2.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 GAM29077.1 - 0.0078 15.5 0.1 0.015 14.5 0.1 1.5 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus PAT1 PF09770.9 GAM29077.1 - 0.14 10.4 25.8 0.17 10.1 25.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gaa1 PF04114.14 GAM29078.1 - 1.3e-40 139.9 22.4 3.2e-40 138.6 19.7 2.7 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component CDC45 PF02724.14 GAM29078.1 - 0.046 12.0 1.1 0.065 11.5 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein LIM PF00412.22 GAM29079.1 - 6.9e-11 42.2 5.8 1.1e-10 41.6 5.8 1.3 1 0 0 1 1 1 1 LIM domain DNA_RNApol_7kD PF03604.13 GAM29079.1 - 0.043 13.5 0.8 0.92 9.2 0.1 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit NinD PF17466.2 GAM29079.1 - 0.086 12.9 0.8 0.29 11.3 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function DiS_P_DiS PF06750.13 GAM29079.1 - 0.1 12.7 1.7 0.16 12.1 1.7 1.4 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Voltage_CLC PF00654.20 GAM29080.1 - 9.7e-97 324.4 27.1 1.4e-96 323.8 23.9 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 GAM29080.1 - 8.4e-11 42.1 0.2 4.4e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain TAT_signal PF10518.9 GAM29080.1 - 0.00094 18.9 2.4 0.00094 18.9 2.4 2.4 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 GAM29080.1 - 0.013 14.8 2.1 0.043 13.2 2.1 1.8 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF373 PF04123.13 GAM29080.1 - 9.3 5.6 12.0 0.51 9.7 6.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF373) Glyco_hydro_18 PF00704.28 GAM29081.1 - 1.5e-19 70.9 2.8 2e-19 70.5 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_transf_49 PF13896.6 GAM29082.1 - 1.8e-52 178.7 1.5 8.7e-42 143.6 1.5 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAM29082.1 - 0.0024 17.7 0.0 0.0062 16.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Lig_chan-Glu_bd PF10613.9 GAM29082.1 - 0.17 12.1 0.8 0.36 11.1 0.3 1.8 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site RWP-RK PF02042.15 GAM29083.1 - 5.5e-06 26.3 0.1 1.2e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 RWP-RK domain APG6_N PF17675.1 GAM29083.1 - 0.096 13.2 5.2 0.2 12.2 0.3 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region Suppressor_APC PF11414.8 GAM29083.1 - 0.48 10.5 4.6 2.5 8.2 2.1 2.8 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein CRAL_TRIO PF00650.20 GAM29084.1 - 2.6e-34 118.2 0.3 5.8e-34 117.1 0.1 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAM29084.1 - 7e-07 29.3 0.4 1.8e-06 28.0 0.4 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain GOLD_2 PF13897.6 GAM29084.1 - 5.1e-06 27.0 9.2 0.00085 19.8 0.4 3.3 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking YflT PF11181.8 GAM29084.1 - 0.023 15.2 0.3 0.7 10.4 0.0 2.6 2 0 0 2 2 2 0 Heat induced stress protein YflT REPA_OB_2 PF16900.5 GAM29084.1 - 0.041 13.8 1.0 0.36 10.8 0.2 2.4 2 0 0 2 2 2 0 Replication protein A OB domain DUF3275 PF11679.8 GAM29084.1 - 0.24 11.3 6.2 0.19 11.7 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) Glyco_transf_49 PF13896.6 GAM29085.1 - 3.2e-54 184.5 5.4 8.2e-46 156.9 2.6 2.8 1 1 2 3 3 3 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAM29085.1 - 0.07 12.9 0.1 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF1084 PF06454.11 GAM29086.1 - 1.9e-09 37.3 28.0 5e-09 35.9 28.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Glyco_transf_49 PF13896.6 GAM29087.1 - 1.2e-48 166.2 4.8 3.4e-41 141.7 4.2 2.5 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_10 PF00852.19 GAM29087.1 - 1.1e-27 97.0 0.1 2.3e-27 95.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term zf-RING_2 PF13639.6 GAM29089.1 - 1.3e-11 44.6 7.4 2.6e-11 43.7 7.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAM29089.1 - 3.7e-09 36.1 6.9 7.1e-09 35.3 6.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAM29089.1 - 1.8e-08 34.6 4.2 7.2e-08 32.6 4.2 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAM29089.1 - 7.1e-06 25.8 6.9 1.5e-05 24.7 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAM29089.1 - 2.9e-05 24.0 7.5 6.7e-05 22.8 7.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAM29089.1 - 0.0001 22.1 7.1 0.00026 20.8 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM29089.1 - 0.00065 19.6 5.3 0.0012 18.7 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 GAM29089.1 - 0.0038 16.8 4.6 0.0076 15.9 4.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 GAM29089.1 - 0.04 13.8 6.3 0.068 13.1 6.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAM29089.1 - 0.04 14.0 2.2 0.087 12.9 2.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Utp14 PF04615.13 GAM29090.1 - 7.1e-128 428.3 78.2 7.1e-128 428.3 78.2 2.1 1 1 1 2 2 2 1 Utp14 protein DUF1713 PF08213.11 GAM29090.1 - 0.028 14.3 9.5 0.18 11.8 9.5 2.5 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) LRR_4 PF12799.7 GAM29092.1 - 6.8e-13 48.6 31.6 1e-07 32.1 0.4 6.0 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAM29092.1 - 2.1e-12 46.6 12.1 0.0001 22.0 0.4 3.8 1 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 GAM29092.1 - 3.1e-10 39.8 2.1 6.7e-05 22.5 1.2 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 GAM29092.1 - 0.011 15.7 13.2 7.4 6.9 1.2 5.7 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 GAM29092.1 - 4.5 8.2 18.8 5 8.1 0.3 7.0 7 0 0 7 7 7 0 Leucine Rich Repeat Beta_helix PF13229.6 GAM29093.1 - 8.5e-15 54.9 36.4 5.7e-10 39.3 5.1 3.8 1 1 2 3 3 3 2 Right handed beta helix region CBM_4_9 PF02018.17 GAM29093.1 - 9.2e-06 26.0 2.0 9.2e-06 26.0 2.0 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain DEC-1_N PF04625.13 GAM29093.1 - 0.27 10.2 1.3 0.42 9.6 1.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region OTU PF02338.19 GAM29094.1 - 1.7e-23 83.5 0.0 1.7e-23 83.5 0.0 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 GAM29094.1 - 5.2e-07 29.4 6.7 0.00039 19.9 0.0 3.4 1 1 2 3 3 3 2 Peptidase C65 Otubain TFIIF_alpha PF05793.12 GAM29095.1 - 2.1e-21 76.2 60.1 2.1e-21 76.2 60.1 3.4 1 1 2 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Curto_V2 PF07325.11 GAM29095.1 - 0.38 10.6 0.0 0.38 10.6 0.0 2.5 3 1 1 4 4 4 0 Curtovirus V2 protein C2 PF00168.30 GAM29096.1 - 2e-21 76.2 0.0 5.4e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 GAM29096.1 - 1.9e-05 25.2 0.0 0.034 14.8 0.0 3.6 3 0 0 3 3 3 1 Putative heavy-metal-binding DUF4156 PF13698.6 GAM29096.1 - 0.0078 16.5 0.0 0.076 13.4 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4156) Pkinase PF00069.25 GAM29099.1 - 4.1e-24 85.4 0.0 1e-23 84.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain DSPc PF00782.20 GAM29099.1 - 9.7e-20 70.7 0.0 2.9e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase_Tyr PF07714.17 GAM29099.1 - 9.3e-13 48.1 0.0 1.7e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Menin PF05053.13 GAM29099.1 - 8.6 4.6 6.3 19 3.4 6.3 1.5 1 0 0 1 1 1 0 Menin RNA_pol_Rpb2_6 PF00562.28 GAM29100.1 - 5e-124 414.3 4.6 4.6e-122 407.8 0.2 2.6 2 1 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAM29100.1 - 2.8e-67 226.2 0.5 4.9e-67 225.4 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 GAM29100.1 - 2.1e-49 167.7 0.0 6.4e-49 166.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GAM29100.1 - 2.6e-35 120.7 0.1 9.4e-35 118.9 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 GAM29100.1 - 2e-25 88.8 0.1 6.4e-25 87.1 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 GAM29100.1 - 2.9e-20 72.3 0.1 1.7e-19 69.9 0.1 2.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 GAM29100.1 - 8.9e-19 67.8 2.7 2.7e-18 66.2 2.7 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Intein_splicing PF14890.6 GAM29100.1 - 2.5e-10 40.4 0.3 6e-10 39.2 0.3 1.7 1 0 0 1 1 1 1 Intein splicing domain Hint PF01079.20 GAM29100.1 - 5.3e-07 29.4 0.8 1.3e-06 28.1 0.8 1.6 1 0 0 1 1 1 1 Hint module PT-HINT PF07591.11 GAM29100.1 - 1.7e-05 25.1 0.6 4.9e-05 23.6 0.3 2.0 2 0 0 2 2 2 1 Pretoxin HINT domain Hom_end_hint PF05203.16 GAM29100.1 - 0.011 15.7 0.3 0.028 14.4 0.1 1.6 1 1 0 1 1 1 0 Hom_end-associated Hint efThoc1 PF11957.8 GAM29101.1 - 5.8e-68 229.7 26.0 1.1e-64 218.9 15.8 2.9 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor AP1AR PF15745.5 GAM29101.1 - 0.029 14.0 5.6 0.055 13.1 5.6 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein NARP1 PF12569.8 GAM29101.1 - 0.056 12.4 9.7 0.092 11.6 9.7 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Homeodomain PF00046.29 GAM29102.1 - 1.8e-14 53.3 3.1 3.5e-14 52.4 3.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAM29102.1 - 0.00022 21.1 1.1 0.00038 20.3 0.0 1.9 2 0 0 2 2 2 1 Homeobox KN domain Tim54 PF11711.8 GAM29102.1 - 5.8 5.6 11.3 3.6 6.3 0.4 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.25 GAM29103.1 - 1.6e-79 267.0 0.0 2.1e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM29103.1 - 3.7e-41 141.1 0.0 5e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAM29103.1 - 0.00084 18.7 0.1 0.0024 17.3 0.0 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAM29103.1 - 0.0029 17.0 0.2 0.018 14.4 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 GAM29103.1 - 0.014 15.0 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family TIG PF01833.24 GAM29104.1 - 1e-05 25.5 0.9 1e-05 25.5 0.9 4.5 4 0 0 4 4 4 2 IPT/TIG domain LRR_4 PF12799.7 GAM29104.1 - 0.023 15.1 1.9 0.023 15.1 1.9 5.9 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) PRIMA1 PF16101.5 GAM29104.1 - 0.063 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 LRR_8 PF13855.6 GAM29104.1 - 0.16 11.8 3.6 3.1 7.6 0.3 4.1 3 0 0 3 3 3 0 Leucine rich repeat EGF_2 PF07974.13 GAM29104.1 - 0.59 10.5 12.0 1.3 9.5 12.0 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 GAM29104.1 - 5.2 7.2 12.4 14 5.9 12.4 1.8 1 0 0 1 1 1 0 Tenascin EGF domain LRR_6 PF13516.6 GAM29104.1 - 5.7 7.3 9.9 13 6.2 0.1 4.0 3 0 0 3 3 3 0 Leucine Rich repeat TIG PF01833.24 GAM29105.1 - 1.3e-05 25.2 1.3 1.3e-05 25.2 1.3 6.2 5 1 0 5 5 5 3 IPT/TIG domain LRR_8 PF13855.6 GAM29105.1 - 0.0053 16.5 19.1 0.0075 16.0 0.2 5.8 6 0 0 6 6 6 2 Leucine rich repeat LRR_4 PF12799.7 GAM29105.1 - 0.48 10.9 33.6 0.19 12.2 0.6 6.3 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 GAM29105.1 - 0.53 10.7 10.7 1.1 9.7 10.7 1.6 1 0 0 1 1 1 0 EGF-like domain LRR_5 PF13306.6 GAM29105.1 - 0.57 10.1 4.6 0.95 9.4 0.6 3.0 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) MMS19_N PF14500.6 GAM29107.1 - 2.1e-84 283.2 22.5 3.2e-83 279.3 0.1 5.0 5 1 1 6 6 6 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 GAM29107.1 - 1.6e-43 149.5 25.7 3.6e-41 141.7 13.8 4.0 2 2 1 3 3 3 2 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 GAM29107.1 - 1.2e-11 44.8 0.7 0.042 14.4 0.0 5.6 5 0 0 5 5 5 3 HEAT-like repeat HEAT PF02985.22 GAM29107.1 - 5.9e-07 29.2 3.2 0.28 11.6 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 GAM29107.1 - 2.5e-05 24.5 0.0 0.078 13.4 0.0 3.5 2 1 0 2 2 2 2 HEAT repeats Vac14_Fab1_bd PF12755.7 GAM29107.1 - 0.00017 22.1 4.5 0.028 15.0 0.3 4.3 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 GAM29107.1 - 0.015 15.4 2.2 8.9 6.5 0.9 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Telomere_reg-2 PF10193.9 GAM29107.1 - 0.82 10.1 13.1 0.45 11.0 0.1 4.5 4 1 1 5 5 5 0 Telomere length regulation protein NOC3p PF07540.11 GAM29107.1 - 1.5 9.3 5.6 3.6 8.1 0.4 4.0 4 1 0 4 4 4 0 Nucleolar complex-associated protein Cpn60_TCP1 PF00118.24 GAM29108.1 - 1.6e-14 53.4 4.3 1.1e-13 50.7 0.6 2.6 3 0 0 3 3 3 2 TCP-1/cpn60 chaperonin family Peptidase_S10 PF00450.22 GAM29108.1 - 0.013 14.9 0.7 3.8 6.8 0.1 2.2 1 1 0 2 2 2 0 Serine carboxypeptidase IF-2B PF01008.17 GAM29108.1 - 0.15 11.2 1.2 11 5.1 0.1 2.2 2 0 0 2 2 2 0 Initiation factor 2 subunit family Glyco_transf_49 PF13896.6 GAM29109.1 - 1.6e-48 165.8 2.9 7.5e-42 143.8 2.8 3.0 2 1 1 3 3 3 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 GAM29109.1 - 0.066 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 RR_TM4-6 PF06459.12 GAM29109.1 - 4.1 7.2 5.7 7.4 6.3 5.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_10 PF00852.19 GAM29110.1 - 4.5e-40 137.2 1.1 5.7e-40 136.9 0.2 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term YARHG PF13308.6 GAM29110.1 - 0.005 16.7 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 YARHG domain Glyco_tran_10_N PF17039.5 GAM29110.1 - 0.039 14.4 0.0 0.097 13.1 0.0 1.7 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal Glyco_trans_1_2 PF13524.6 GAM29110.1 - 0.14 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_hydro_18 PF00704.28 GAM29111.1 - 8.7e-25 88.1 0.1 1.1e-24 87.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Nodulin_late PF07127.11 GAM29111.1 - 0.035 14.4 0.6 0.86 10.0 0.1 2.4 2 0 0 2 2 2 0 Late nodulin protein Glyco_transf_10 PF00852.19 GAM29112.1 - 8.9e-34 116.7 1.0 1.6e-33 115.9 1.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 GAM29112.1 - 0.003 18.0 0.0 0.0068 16.9 0.0 1.6 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal G10 PF01125.17 GAM29114.1 - 7e-64 214.0 7.9 7.7e-64 213.9 7.9 1.0 1 0 0 1 1 1 1 G10 protein DUF1084 PF06454.11 GAM29115.1 - 5.8e-08 32.4 26.0 1.2e-07 31.4 26.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) ASFV_J13L PF05568.11 GAM29115.1 - 0.35 10.6 4.4 0.94 9.2 4.4 1.7 1 0 0 1 1 1 0 African swine fever virus J13L protein Sec23_trunk PF04811.15 GAM29116.1 - 2.2e-66 223.9 0.5 5.5e-66 222.6 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAM29116.1 - 6.6e-26 90.1 0.9 6.6e-26 90.1 0.9 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAM29116.1 - 1.3e-17 64.3 0.2 3e-17 63.1 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAM29116.1 - 1.8e-17 63.1 1.7 3.5e-17 62.2 1.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAM29116.1 - 9.2e-05 22.3 0.0 9.2e-05 22.3 0.0 3.3 4 0 0 4 4 4 1 Gelsolin repeat Pkinase_Tyr PF07714.17 GAM29117.1 - 4.2e-53 180.3 0.0 7.2e-53 179.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM29117.1 - 1.9e-46 158.6 0.0 2.9e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 GAM29117.1 - 6.9e-18 65.0 7.3 3.2e-09 37.2 0.5 4.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM29117.1 - 3.4e-14 53.0 0.8 1.3e-09 38.4 0.1 4.6 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM29117.1 - 3.2e-11 42.4 0.7 0.12 13.0 0.0 6.4 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 GAM29117.1 - 2.9e-09 36.9 6.8 0.0015 18.9 0.1 6.1 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 GAM29117.1 - 1.8e-08 34.5 1.9 0.012 16.0 0.2 5.1 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Kinase-like PF14531.6 GAM29117.1 - 0.00054 19.4 0.0 0.0011 18.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAM29117.1 - 0.00069 18.7 0.1 0.002 17.1 0.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAM29117.1 - 0.0094 15.9 3.3 0.038 13.9 0.0 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family NDT80_PhoG PF05224.12 GAM29119.1 - 1.5e-28 100.3 0.1 1.5e-28 100.3 0.1 3.6 2 2 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.6 GAM29119.1 - 2.8e-08 33.9 0.0 5.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase MRF_C1 PF13887.6 GAM29119.1 - 0.00083 18.5 0.0 0.0017 17.5 0.0 1.5 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 ThrE PF06738.12 GAM29119.1 - 0.0026 17.2 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative threonine/serine exporter CCDC-167 PF15188.6 GAM29119.1 - 0.014 15.7 0.9 0.084 13.2 0.1 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FAM131 PF15010.6 GAM29119.1 - 0.75 9.6 11.9 1.4 8.7 11.9 1.5 1 0 0 1 1 1 0 Putative cell signalling Membralin PF09746.9 GAM29119.1 - 9 5.2 8.3 17 4.3 8.3 1.4 1 0 0 1 1 1 0 Tumour-associated protein Methyltransf_31 PF13847.6 GAM29120.1 - 4.3e-17 62.3 0.0 5.8e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAM29120.1 - 5.8e-13 49.4 0.0 8.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAM29120.1 - 1.2e-11 45.1 0.0 2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAM29120.1 - 5.9e-10 39.8 0.0 8.6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAM29120.1 - 7.5e-09 35.6 0.0 1.1e-08 35.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 GAM29120.1 - 4.2e-07 29.6 0.0 6.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 GAM29120.1 - 1e-06 28.4 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAM29120.1 - 2.3e-05 23.9 0.1 3.4e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 GAM29120.1 - 0.0069 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF1363 PF07101.11 GAM29120.1 - 0.015 15.6 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) Pox_MCEL PF03291.16 GAM29120.1 - 0.024 13.7 0.1 0.039 13.1 0.1 1.4 1 1 0 1 1 1 0 mRNA capping enzyme DUF4213 PF13938.6 GAM29120.1 - 0.026 14.7 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative heavy-metal chelation Methyltransf_32 PF13679.6 GAM29120.1 - 0.026 14.5 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 GAM29120.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 GAM29120.1 - 0.13 12.2 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain SIR2 PF02146.17 GAM29121.1 - 5.9e-25 88.2 0.0 1.2e-24 87.3 0.0 1.4 2 0 0 2 2 2 1 Sir2 family HTH_8 PF02954.19 GAM29121.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family tRNA-synt_2b PF00587.25 GAM29123.1 - 1.4e-36 126.2 0.0 2.8e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAM29123.1 - 1.6e-20 73.0 0.8 3.2e-20 72.1 0.8 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 GAM29123.1 - 1.5e-12 47.4 0.0 3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 GAM29123.1 - 8.3e-11 41.8 0.1 5e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 TGS domain UvsW PF11637.8 GAM29123.1 - 0.063 13.4 1.1 0.25 11.5 0.0 2.6 4 0 0 4 4 4 0 ATP-dependant DNA helicase UvsW LRR_8 PF13855.6 GAM29124.1 - 1.8e-21 75.7 17.8 1.1e-09 37.9 2.0 4.8 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 GAM29124.1 - 4.2e-18 65.1 19.2 0.00084 19.7 0.1 6.3 3 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAM29124.1 - 4.7e-09 36.0 0.8 0.00078 19.0 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 GAM29124.1 - 0.00013 21.7 17.3 18 5.7 0.0 8.8 9 0 0 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.33 GAM29124.1 - 0.0002 21.5 22.8 18 6.4 2.2 9.0 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_5 PF13306.6 GAM29124.1 - 0.0012 18.8 0.1 0.008 16.1 0.1 1.7 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) GDP_Man_Dehyd PF16363.5 GAM29125.1 - 2.1e-72 244.4 0.1 2.5e-72 244.1 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAM29125.1 - 6.7e-64 215.6 0.3 8.7e-64 215.3 0.3 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM29125.1 - 2.2e-25 89.2 0.0 3.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAM29125.1 - 5.6e-23 81.5 0.0 2.7e-17 62.9 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAM29125.1 - 6.5e-19 68.1 0.0 9.7e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAM29125.1 - 2.9e-18 66.0 0.1 1.7e-15 56.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GAM29125.1 - 8.7e-07 29.0 0.0 5e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 GAM29125.1 - 0.081 12.8 0.2 0.3 11.0 0.2 1.9 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 GAM29125.1 - 0.087 12.3 0.1 5.6 6.4 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Ank_4 PF13637.6 GAM29126.1 - 6.6e-21 74.4 1.9 4e-11 43.2 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAM29126.1 - 1.1e-15 57.3 1.7 4.3e-09 36.4 0.4 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 GAM29126.1 - 6.3e-14 51.9 0.6 4.4e-08 33.2 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM29126.1 - 5.5e-13 49.3 0.1 8.2e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAM29126.1 - 7.2e-12 44.4 0.6 5.9e-06 26.2 0.2 3.0 3 0 0 3 3 3 2 Ankyrin repeat DUF3094 PF11293.8 GAM29127.1 - 0.044 13.5 0.2 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) MMR_HSR1_Xtn PF16897.5 GAM29128.1 - 9.4e-41 138.1 0.2 1.8e-40 137.3 0.2 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 GAM29128.1 - 7.1e-23 80.4 0.0 1.2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 GAM29128.1 - 8.5e-20 70.9 0.0 1.6e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAM29128.1 - 1.7e-08 34.2 0.0 2.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAM29128.1 - 0.0039 17.3 0.1 0.44 10.6 0.0 2.3 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.10 GAM29128.1 - 0.06 12.8 0.1 0.15 11.5 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAM29128.1 - 0.069 13.0 0.1 0.23 11.3 0.1 1.9 1 1 0 1 1 1 0 RsgA GTPase AIG1 PF04548.16 GAM29128.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 GAM29128.1 - 0.093 11.7 0.3 0.31 10.0 0.1 2.0 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAM29128.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 GAM29128.1 - 0.14 12.4 0.1 0.4 10.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 GAM29128.1 - 0.15 12.3 0.1 0.57 10.4 0.0 2.0 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase KTI12 PF08433.10 GAM29128.1 - 0.18 11.3 0.1 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Y_phosphatase2 PF03162.13 GAM29129.1 - 1.2e-06 28.2 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 GAM29129.1 - 3.6e-06 26.8 0.0 5.2e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.20 GAM29129.1 - 7.6e-06 25.8 0.0 1.9e-05 24.5 0.0 1.7 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 GAM29129.1 - 5.6e-05 23.2 0.0 8.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 GAM29129.1 - 0.00079 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 GAM29129.1 - 0.0024 17.5 0.0 0.0041 16.7 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase MtrB PF05440.12 GAM29129.1 - 0.08 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B RRM_1 PF00076.22 GAM29132.1 - 2.4e-27 94.5 6.8 1e-11 44.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAGA-Tad1 PF12767.7 GAM29133.1 - 1.2e-13 51.4 3.2 1.4e-13 51.1 0.4 2.1 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit BSP_II PF05432.11 GAM29133.1 - 0.81 9.3 21.6 0.11 12.1 11.3 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) SAGA-Tad1 PF12767.7 GAM29134.1 - 9.6e-14 51.7 0.4 9.6e-14 51.7 0.4 1.9 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit CENP-B_dimeris PF09026.10 GAM29134.1 - 0.02 15.2 1.4 0.025 15.0 1.4 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AIM3 PF17096.5 GAM29134.1 - 0.071 14.1 4.9 0.085 13.8 4.9 1.2 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Atrophin-1 PF03154.15 GAM29134.1 - 0.079 11.3 1.8 0.087 11.1 1.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.6 GAM29134.1 - 0.47 10.4 7.1 0.63 10.0 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) FAM176 PF14851.6 GAM29134.1 - 0.98 9.1 2.9 1.1 8.9 2.9 1.1 1 0 0 1 1 1 0 FAM176 family DEAD PF00270.29 GAM29135.1 - 1.3e-43 148.8 1.5 1.3e-43 148.8 1.5 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAM29135.1 - 5.3e-34 116.9 0.2 2.6e-32 111.4 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 GAM29135.1 - 3.8e-06 26.7 0.4 7.3e-06 25.8 0.1 1.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 GAM29135.1 - 6.3e-05 23.0 0.1 0.00015 21.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAM29135.1 - 0.00012 21.0 0.0 0.21 10.3 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 tRNA-synt_1b PF00579.25 GAM29135.1 - 0.0016 17.8 0.0 0.0043 16.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) AAA_19 PF13245.6 GAM29135.1 - 0.0047 17.3 1.5 0.01 16.2 0.3 2.0 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 GAM29135.1 - 0.018 14.4 0.0 0.054 12.8 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit FNIP PF05725.12 GAM29136.1 - 2.3e-15 56.4 9.8 1e-08 35.2 0.0 4.2 4 0 0 4 4 4 3 FNIP Repeat 2OG-FeII_Oxy_3 PF13640.6 GAM29137.1 - 4.3e-09 37.2 0.0 1.2e-08 35.8 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Repressor_Mnt PF11423.8 GAM29137.1 - 0.033 14.0 0.4 0.24 11.2 0.4 2.4 2 0 0 2 2 2 0 Regulatory protein Mnt BppL_N PF18338.1 GAM29138.1 - 0.0061 16.3 2.5 0.0061 16.3 2.5 2.3 2 0 0 2 2 2 1 Lower baseplate protein N-terminal domain p450 PF00067.22 GAM29140.1 - 8.2e-12 44.6 0.3 4.7e-07 28.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Exonuc_VII_L PF02601.15 GAM29141.1 - 0.089 12.3 1.9 0.12 11.9 1.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 GAM29141.1 - 0.092 13.1 6.0 0.14 12.5 6.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GTP_EFTU_D3 PF03143.17 GAM29141.1 - 0.099 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain eIF-4B PF06273.11 GAM29141.1 - 0.19 10.7 3.6 0.27 10.2 3.6 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B UPF0242 PF06785.11 GAM29141.1 - 0.45 10.6 9.6 0.67 10.0 9.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PFEMP PF03011.15 GAM29141.1 - 0.78 10.4 3.9 1.3 9.6 3.9 1.3 1 0 0 1 1 1 0 PFEMP DBL domain DUF5384 PF17358.2 GAM29141.1 - 1.6 8.8 11.2 2.4 8.2 11.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5384) SdrD_B PF17210.3 GAM29143.1 - 0.00028 21.1 1.7 0.046 14.0 0.6 2.2 2 0 0 2 2 2 2 SdrD B-like domain Alpha-amylase_C PF02806.18 GAM29143.1 - 0.082 13.4 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain p450 PF00067.22 GAM29144.1 - 2.8e-102 342.8 0.0 3.3e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF455 PF04305.14 GAM29144.1 - 0.15 11.6 0.0 5.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF455) Sec7 PF01369.20 GAM29145.1 - 5.5e-59 198.9 1.9 5.5e-59 198.9 1.9 2.5 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 GAM29145.1 - 2.6e-32 111.9 2.0 2.6e-32 111.9 2.0 5.6 7 0 0 7 7 7 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAM29145.1 - 2.2e-23 81.9 7.3 3.4e-21 74.9 0.2 5.4 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) DCB PF16213.5 GAM29145.1 - 1.1e-06 28.4 3.5 1.1e-06 28.4 3.5 4.2 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 SH3_9 PF14604.6 GAM29146.1 - 2.5e-18 65.7 0.2 4.2e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 GAM29146.1 - 2.6e-18 65.4 0.5 2.2e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAM29146.1 - 1.9e-13 49.8 0.4 3.6e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 SH3 domain CSN8_PSD8_EIF3K PF10075.9 GAM29147.1 - 1.7e-26 92.9 1.2 3.4e-26 91.9 0.1 2.0 2 1 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 GAM29147.1 - 0.00034 20.1 1.7 0.00039 19.9 1.4 1.3 1 1 0 1 1 1 1 SAC3/GANP family DUF3888 PF13027.6 GAM29147.1 - 0.073 13.5 0.8 0.8 10.2 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3888) PDDEXK_9 PF08011.11 GAM29147.1 - 0.18 11.8 1.3 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily PCI PF01399.27 GAM29148.1 - 3e-14 53.4 1.0 6.2e-14 52.4 0.1 2.0 2 0 0 2 2 2 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 GAM29148.1 - 9.7e-06 25.7 0.3 3.4e-05 23.9 0.3 2.0 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain TPR_19 PF14559.6 GAM29148.1 - 0.008 16.7 0.5 0.035 14.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM29148.1 - 0.095 13.0 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM29148.1 - 0.19 11.9 0.9 1.6 8.9 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MCM_N PF14551.6 GAM29148.1 - 0.26 11.9 1.6 3 8.5 1.6 2.5 1 1 0 1 1 1 0 MCM N-terminal domain DUF2804 PF10974.8 GAM29149.1 - 3.7e-100 335.6 2.0 4.2e-100 335.5 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) MIF4G PF02854.19 GAM29151.1 - 4.4e-32 111.4 9.6 3.8e-31 108.4 6.1 2.4 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 GAM29151.1 - 9.9e-06 25.5 7.9 0.00056 19.9 0.2 2.9 3 0 0 3 3 3 2 MA3 domain Uso1_p115_head PF04869.14 GAM29152.1 - 1e-40 139.8 1.9 2e-40 138.8 0.5 2.2 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region PolyA_pol PF01743.20 GAM29152.1 - 0.004 17.6 1.2 0.004 17.6 1.2 1.9 2 0 0 2 2 2 1 Poly A polymerase head domain Atx10homo_assoc PF09759.9 GAM29152.1 - 0.026 14.5 0.4 0.026 14.5 0.4 4.1 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain NIF PF03031.18 GAM29155.1 - 6.4e-58 194.9 0.4 8.5e-58 194.6 0.4 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 GAM29155.1 - 0.0011 19.4 0.1 0.0092 16.4 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Xpo1 PF08389.12 GAM29156.1 - 3.6e-17 62.8 17.0 4.9e-17 62.4 0.3 6.5 6 1 1 7 7 7 1 Exportin 1-like protein IBN_N PF03810.19 GAM29156.1 - 0.0055 16.6 0.2 0.051 13.5 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain FAM199X PF15814.5 GAM29156.1 - 0.0069 15.5 0.5 0.013 14.6 0.5 1.4 1 0 0 1 1 1 1 Protein family FAM199X DUF4042 PF13251.6 GAM29156.1 - 0.13 11.9 0.6 2.1 8.0 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4042) DUF1722 PF08349.11 GAM29156.1 - 0.3 11.4 0.1 0.3 11.4 0.1 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1722) DUF613 PF04764.12 GAM29156.1 - 0.63 10.2 10.7 0.72 10.0 0.4 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF613) DUF1736 PF08409.11 GAM29157.1 - 6.5e-10 38.9 2.5 6.5e-10 38.9 2.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) TPR_1 PF00515.28 GAM29157.1 - 7e-07 28.8 0.4 9.7e-06 25.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAM29157.1 - 9.8e-07 28.7 2.3 0.62 10.6 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM29157.1 - 9.9e-06 25.3 0.2 0.00018 21.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM29157.1 - 0.00011 22.4 0.6 0.074 13.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAM29157.1 - 0.0029 17.2 1.2 0.072 12.8 0.8 2.6 1 1 1 2 2 2 1 TPR repeat TPR_8 PF13181.6 GAM29157.1 - 0.0082 16.3 1.0 0.17 12.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM29157.1 - 0.0085 16.6 0.4 1.4 9.5 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.6 GAM29157.1 - 0.034 13.6 0.2 2 7.8 0.1 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP CD34_antigen PF06365.12 GAM29157.1 - 0.083 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Mad3_BUB1_I PF08311.12 GAM29157.1 - 0.12 12.3 1.6 0.58 10.1 0.1 2.4 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 GAM29157.1 - 0.13 13.0 0.0 0.96 10.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3687 PF12459.8 GAM29158.1 - 0.022 14.3 0.6 0.046 13.2 0.0 1.8 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein MDFI PF15316.6 GAM29158.1 - 0.045 13.9 0.0 0.096 12.8 0.0 1.5 1 1 0 1 1 1 0 MyoD family inhibitor SLATT_fungal PF18142.1 GAM29158.1 - 0.079 13.0 1.0 0.24 11.4 0.3 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Actin PF00022.19 GAM29159.1 - 1e-48 166.0 0.0 1.2e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.19 GAM29160.1 - 1.2e-81 274.4 0.0 5.4e-81 272.3 0.0 1.8 1 1 0 1 1 1 1 Actin YdaS_antitoxin PF15943.5 GAM29161.1 - 0.0081 16.0 0.1 0.11 12.4 0.0 2.3 1 1 1 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Pro_CA PF00484.19 GAM29161.1 - 0.014 15.7 4.7 0.052 13.8 4.7 1.9 1 1 0 1 1 1 0 Carbonic anhydrase RPAP2_Rtr1 PF04181.13 GAM29161.1 - 0.3 11.4 2.9 0.59 10.5 2.9 1.7 1 1 0 1 1 1 0 Rtr1/RPAP2 family Ribosomal_S19e PF01090.19 GAM29162.1 - 2.9e-51 172.8 0.0 3.5e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L21e PF01157.18 GAM29163.1 - 1.6e-41 140.2 5.2 1.7e-41 140.2 4.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e IBN_N PF03810.19 GAM29164.1 - 2.1e-07 30.7 1.0 2.1e-07 30.7 1.0 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain Rif1_N PF12231.8 GAM29164.1 - 0.00083 18.5 1.6 0.0086 15.1 0.6 2.9 2 1 1 3 3 3 2 Rap1-interacting factor 1 N terminal CRM1_repeat PF18777.1 GAM29164.1 - 0.064 12.8 0.2 0.064 12.8 0.2 2.0 2 0 0 2 2 2 0 Chromosome region maintenance or exportin repeat RPN5_C PF18098.1 GAM29164.1 - 0.064 13.4 1.2 0.22 11.6 1.2 2.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain Colicin_K PF17500.2 GAM29164.1 - 0.094 13.3 0.1 1.1 9.8 0.1 2.8 2 0 0 2 2 2 0 Colicin-K Kelch_1 PF01344.25 GAM29165.1 - 7.7e-43 143.8 15.3 1.6e-11 43.6 0.4 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAM29165.1 - 1.9e-37 126.3 21.3 1.4e-07 31.5 0.3 6.9 6 1 1 7 7 7 6 Kelch motif Kelch_5 PF13854.6 GAM29165.1 - 1.3e-34 117.6 22.1 1.3e-08 34.6 0.3 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAM29165.1 - 2.1e-33 114.0 15.9 2.1e-07 31.0 0.1 7.6 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_4 PF13418.6 GAM29165.1 - 5.9e-30 103.0 14.0 5.2e-06 26.4 1.3 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 GAM29165.1 - 3.6e-29 99.6 16.8 5.4e-07 29.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif F-box PF00646.33 GAM29165.1 - 7.8e-07 28.8 0.4 1.8e-06 27.7 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAM29165.1 - 1.2e-06 28.3 0.9 1.2e-06 28.3 0.9 2.0 2 0 0 2 2 2 1 F-box-like RAG2 PF03089.14 GAM29165.1 - 0.013 14.6 0.1 0.51 9.3 0.0 3.0 4 0 0 4 4 4 0 Recombination activating protein 2 CDI PF02234.19 GAM29166.1 - 0.089 13.0 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor PRKCSH_1 PF13015.6 GAM29167.1 - 0.0013 18.4 1.2 0.0016 18.1 1.2 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Man-6-P_recep PF02157.15 GAM29167.1 - 0.0026 16.9 0.4 0.0033 16.6 0.4 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 GAM29167.1 - 0.0036 17.2 6.0 0.0056 16.6 6.0 1.4 1 1 0 1 1 1 1 Autophagy-related protein 27 DCAF17 PF15802.5 GAM29167.1 - 0.059 12.0 0.0 0.08 11.6 0.0 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 17 RasGEF PF00617.19 GAM29168.1 - 3.1e-29 102.4 2.0 5.3e-29 101.7 0.6 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 GAM29168.1 - 8.4e-16 58.1 1.0 5.4e-15 55.5 1.0 2.5 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGAP PF00620.27 GAM29168.1 - 1.7e-14 53.9 0.0 5.4e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain Pribosyltran_N PF13793.6 GAM29169.1 - 8.1e-47 158.0 0.4 2.9e-45 152.9 0.0 2.5 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAM29169.1 - 2.7e-29 102.5 3.3 1.6e-28 100.0 1.6 2.5 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAM29169.1 - 1.8e-06 27.6 1.1 3.5e-06 26.6 1.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Dus PF01207.17 GAM29170.1 - 4.6e-48 163.9 1.5 1.6e-47 162.1 1.5 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) MGC-24 PF05283.11 GAM29170.1 - 0.065 13.7 8.5 0.2 12.1 8.5 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Dicty_REP PF05086.12 GAM29170.1 - 0.33 8.9 13.4 0.46 8.4 13.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 GAM29170.1 - 4.9 7.1 33.1 0.36 10.8 27.5 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein TIG PF01833.24 GAM29171.1 - 1.3e-07 31.6 1.6 4.8e-07 29.8 1.6 2.0 1 0 0 1 1 1 1 IPT/TIG domain FXa_inhibition PF14670.6 GAM29171.1 - 1.6e-06 28.3 10.5 1.6e-06 28.3 10.5 4.8 5 0 0 5 5 5 2 Coagulation Factor Xa inhibitory site EGF_2 PF07974.13 GAM29171.1 - 0.023 15.1 13.9 0.023 15.1 13.9 5.3 6 0 0 6 6 6 0 EGF-like domain FXa_inhibition PF14670.6 GAM29172.1 - 1.4e-14 54.0 27.6 2.4e-09 37.3 9.3 3.5 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site TIG PF01833.24 GAM29172.1 - 8.3e-07 29.0 1.3 4.6e-06 26.6 1.1 2.4 2 0 0 2 2 2 1 IPT/TIG domain cEGF PF12662.7 GAM29172.1 - 0.0018 18.2 13.1 0.0033 17.3 1.5 3.6 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF_2 PF07974.13 GAM29172.1 - 0.037 14.4 18.2 0.037 14.4 18.2 4.4 4 0 0 4 4 4 0 EGF-like domain EGF_3 PF12947.7 GAM29172.1 - 1.5 9.0 46.2 0.22 11.8 9.1 3.9 3 0 0 3 3 3 0 EGF domain Coiled PF05710.12 GAM29173.1 - 0.03 15.2 9.4 0.031 15.1 9.4 1.2 1 1 0 1 1 1 0 Coiled coil UQ_con PF00179.26 GAM29174.1 - 5e-48 162.3 0.2 5.6e-48 162.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAM29174.1 - 0.0046 16.7 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAM29174.1 - 0.0091 16.3 0.1 0.014 15.6 0.1 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 GAM29174.1 - 0.049 13.5 0.1 0.093 12.6 0.1 1.5 1 0 0 1 1 1 0 UEV domain Xpo1 PF08389.12 GAM29175.1 - 2.5e-11 43.9 0.3 2.5e-11 43.9 0.3 5.9 5 1 2 7 7 7 1 Exportin 1-like protein RE_HindVP PF09519.10 GAM29175.1 - 0.0011 18.0 0.2 0.0035 16.4 0.2 1.8 1 0 0 1 1 1 1 HindVP restriction endonuclease Spt20 PF12090.8 GAM29175.1 - 0.012 15.2 26.3 0.34 10.5 9.3 2.5 2 0 0 2 2 2 0 Spt20 family BBP1_N PF15271.6 GAM29175.1 - 0.039 14.7 6.3 0.28 12.0 1.3 3.0 3 0 0 3 3 3 0 Spindle pole body component BBP1, Mps2-binding protein DUF2722 PF10846.8 GAM29175.1 - 0.38 9.7 20.2 0.033 13.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) MACPF PF01823.19 GAM29175.1 - 0.76 9.8 6.8 0.093 12.8 0.9 2.5 3 0 0 3 3 3 0 MAC/Perforin domain EPL1 PF10513.9 GAM29175.1 - 1 9.7 7.3 4.9 7.5 1.4 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF3446 PF11928.8 GAM29175.1 - 1.5 9.1 13.5 0.21 11.9 8.1 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain SUIM_assoc PF16619.5 GAM29175.1 - 3.1 7.9 28.5 1.8 8.7 8.9 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Suf PF05843.14 GAM29175.1 - 3.8 7.4 9.8 3.2 7.6 1.4 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TCP PF03634.13 GAM29175.1 - 4.2 7.9 11.6 8.5 6.9 5.6 2.8 3 0 0 3 3 3 0 TCP family transcription factor TFIIA PF03153.13 GAM29175.1 - 5 7.0 25.5 1.5 8.7 5.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF5327 PF17261.2 GAM29175.1 - 7 7.5 15.3 0.54 11.0 4.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Cellulase PF00150.18 GAM29176.1 - 5.3e-23 81.8 0.1 9.7e-18 64.6 0.0 2.5 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 GAM29176.1 - 6.4e-14 52.3 0.4 1.1e-13 51.5 0.4 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_1 PF00232.18 GAM29176.1 - 0.008 14.6 0.1 0.013 13.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_35 PF01301.19 GAM29176.1 - 0.045 13.4 0.1 0.093 12.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 PHF5 PF03660.14 GAM29177.1 - 4.3e-48 161.8 11.9 4.8e-48 161.7 11.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 GAM29177.1 - 0.028 12.3 8.3 0.029 12.3 8.3 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 CbiC PF02570.15 GAM29177.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Precorrin-8X methylmutase DZR PF12773.7 GAM29177.1 - 4.1 7.5 17.7 2.6 8.1 2.7 3.3 1 1 1 2 2 2 0 Double zinc ribbon RhoGEF PF00621.20 GAM29179.1 - 1.9e-34 119.5 0.1 3.7e-34 118.5 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 GAM29179.1 - 0.0012 19.4 0.0 0.0031 18.0 0.0 1.8 1 0 0 1 1 1 1 PH domain Toxin_YhaV PF11663.8 GAM29179.1 - 0.065 13.3 0.1 0.75 9.8 0.0 2.3 2 0 0 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system Rogdi_lz PF10259.9 GAM29181.1 - 8e-17 61.6 8.5 4.8e-11 42.6 6.4 2.9 2 1 0 2 2 2 2 Rogdi leucine zipper containing protein DUF572 PF04502.13 GAM29182.1 - 3.4e-79 266.9 21.4 1.9e-78 264.4 21.4 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-PHD-like PF15446.6 GAM29182.1 - 0.0094 15.6 3.4 0.024 14.3 3.4 1.8 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain HypA PF01155.19 GAM29182.1 - 0.062 13.3 0.3 3.9 7.5 0.0 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Yippee-Mis18 PF03226.14 GAM29182.1 - 0.07 13.4 0.1 14 5.9 0.0 2.9 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2610 PF11020.8 GAM29182.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) RNA_pol_N PF01194.17 GAM29182.1 - 0.17 12.2 3.2 0.89 9.9 0.1 2.8 2 1 0 2 2 2 0 RNA polymerases N / 8 kDa subunit TF_Zn_Ribbon PF08271.12 GAM29182.1 - 0.33 10.5 2.8 0.32 10.6 0.2 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-Sec23_Sec24 PF04810.15 GAM29182.1 - 1.8 8.7 4.0 30 4.8 0.1 2.5 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zf-MIZ PF02891.20 GAM29183.1 - 5.2e-17 61.3 8.6 1.2e-16 60.2 8.6 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 GAM29183.1 - 0.00016 21.4 3.0 0.00041 20.1 3.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 GAM29183.1 - 0.56 10.3 6.3 1.2 9.2 6.3 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger ATG27 PF09451.10 GAM29184.1 - 3.9e-31 108.9 3.8 7.3e-31 108.0 3.8 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 GAM29184.1 - 8.1e-10 38.2 8.9 5.4e-06 25.7 0.7 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate receptor PRKCSH_1 PF13015.6 GAM29184.1 - 3.7e-05 23.5 0.2 5.4e-05 22.9 0.2 1.4 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein OppC_N PF12911.7 GAM29184.1 - 0.066 13.2 0.0 2.2 8.3 0.1 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF4971 PF16341.5 GAM29184.1 - 0.1 12.5 3.0 0.71 9.7 0.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4971) ATG27 PF09451.10 GAM29185.1 - 1.7e-32 113.3 0.3 5.2e-32 111.7 0.3 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 GAM29185.1 - 2e-06 27.9 0.9 8.3e-05 22.7 0.7 2.1 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 GAM29185.1 - 1e-05 25.3 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Man-6-P_recep PF02157.15 GAM29185.1 - 7.2e-05 22.0 2.3 0.00037 19.7 2.3 2.0 1 1 0 1 1 1 1 Mannose-6-phosphate receptor ECSCR PF15820.5 GAM29185.1 - 0.05 13.4 0.2 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator TMEMspv1-c74-12 PF11044.8 GAM29185.1 - 3.8 7.6 10.9 0.051 13.6 3.7 1.6 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein IBN_N PF03810.19 GAM29186.1 - 1.2e-06 28.3 0.0 1.2e-06 28.3 0.0 3.7 4 1 1 5 5 5 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 GAM29186.1 - 0.012 15.7 0.0 0.77 9.8 0.0 3.3 3 0 0 3 3 3 0 Importin 13 repeat DUF1539 PF07560.11 GAM29186.1 - 0.017 15.2 4.4 0.43 10.7 0.0 3.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1539) EF-G-binding_N PF07299.11 GAM29186.1 - 0.063 13.8 2.4 3.1 8.4 0.6 3.8 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal Imm5 PF14423.6 GAM29186.1 - 0.33 11.2 1.9 3 8.0 0.1 2.8 3 0 0 3 3 3 0 Immunity protein Imm5 Ribosomal_L27A PF00828.19 GAM29187.1 - 5.2e-20 72.4 0.0 6.8e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Glyco_hydro_38N PF01074.22 GAM29188.1 - 2.5e-97 325.7 4.0 3.8e-97 325.1 4.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAM29188.1 - 3.1e-34 118.9 0.1 5.4e-34 118.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAM29188.1 - 9.1e-19 67.4 0.2 2e-18 66.3 0.2 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAM29188.1 - 0.00036 20.6 0.0 0.0009 19.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 GAM29188.1 - 0.0061 15.8 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Viral_NABP PF05515.11 GAM29189.1 - 0.0014 18.5 1.1 0.0024 17.8 1.1 1.3 1 0 0 1 1 1 1 Viral nucleic acid binding Agenet PF05641.12 GAM29189.1 - 0.0043 17.5 0.0 0.02 15.4 0.0 2.1 1 0 0 1 1 1 1 Agenet domain Dicty_REP PF05086.12 GAM29189.1 - 3.9 5.3 8.8 6.4 4.6 8.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Clat_adaptor_s PF01217.20 GAM29190.1 - 1.3e-07 31.6 2.9 1.7e-07 31.3 2.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AMP-binding PF00501.28 GAM29191.1 - 2.9e-54 184.3 0.0 4.7e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAM29191.1 - 5e-53 179.9 0.0 7.8e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 GAM29191.1 - 5.5e-09 36.3 0.0 1.7e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 GAM29191.1 - 8.1e-06 25.5 0.0 3e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAM29191.1 - 0.00013 21.1 0.2 0.0018 17.4 0.2 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ZZ PF00569.17 GAM29191.1 - 0.0092 15.8 10.3 0.02 14.7 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type adh_short PF00106.25 GAM29192.1 - 9.8e-43 145.9 0.0 1.3e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM29192.1 - 2.4e-34 118.9 0.0 3.6e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAM29192.1 - 5.9e-08 32.4 0.0 7.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 GAM29192.1 - 7e-07 29.3 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAM29192.1 - 0.00013 21.5 0.1 0.0025 17.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAM29192.1 - 0.12 11.4 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain eRF1_1 PF03463.15 GAM29193.1 - 2.5e-45 153.6 1.6 4.4e-45 152.8 1.6 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 GAM29193.1 - 1.2e-24 87.2 0.0 1.9e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAM29193.1 - 3.6e-23 82.2 0.0 8.9e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 DUF5601 PF18151.1 GAM29193.1 - 0.056 13.8 1.1 0.23 11.8 1.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) Nif11 PF07862.11 GAM29193.1 - 0.083 13.2 1.0 4.5 7.6 0.1 3.1 2 1 1 3 3 3 0 Nif11 domain CobT PF06213.12 GAM29193.1 - 0.18 11.2 11.0 0.28 10.5 11.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 GAM29193.1 - 0.33 9.0 17.4 0.55 8.3 17.4 1.5 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GAM29193.1 - 1.9 6.7 9.3 2.7 6.2 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1604 PF07713.13 GAM29194.1 - 7.6e-37 125.0 2.6 7.6e-37 125.0 2.6 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.23 GAM29194.1 - 5.1e-05 23.1 0.2 0.00012 21.9 0.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAM29194.1 - 0.022 14.8 0.0 0.022 14.8 0.0 3.9 4 0 0 4 4 4 0 G-patch domain SR-25 PF10500.9 GAM29194.1 - 2.7 7.5 48.3 0.18 11.4 42.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ArfGap PF01412.18 GAM29196.1 - 2.4e-41 140.5 0.0 4.9e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 GAM29196.1 - 3.8e-10 40.2 0.1 7.7e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_15 PF17339.2 GAM29196.1 - 0.027 14.4 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 PH domain PH_11 PF15413.6 GAM29196.1 - 0.033 14.6 0.1 0.21 12.0 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PAP2_C PF14360.6 GAM29196.1 - 0.038 14.5 0.1 0.095 13.2 0.0 1.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal PH_2 PF08458.10 GAM29196.1 - 0.083 13.2 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Glyco_hydro_9 PF00759.19 GAM29197.1 - 1.8e-125 419.6 11.4 2.1e-125 419.4 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 MFS_1 PF07690.16 GAM29198.1 - 5.7e-47 160.3 29.0 5.7e-47 160.3 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAM29198.1 - 7.9e-11 41.9 2.2 7.9e-11 41.9 2.2 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 GAM29198.1 - 0.00024 19.5 0.2 0.00024 19.5 0.2 2.2 2 0 0 2 2 2 1 BT1 family Pkinase PF00069.25 GAM29199.1 - 2.9e-79 266.2 0.0 3.3e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM29199.1 - 2.3e-38 132.0 0.0 2.7e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM29199.1 - 3.8e-07 29.7 0.1 4e-05 23.1 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 GAM29199.1 - 5.7e-06 25.8 0.0 8.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAM29199.1 - 8.9e-05 21.4 0.0 0.00017 20.5 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 GAM29199.1 - 0.0048 16.8 0.0 0.062 13.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAM29199.1 - 0.0078 15.2 0.3 0.028 13.4 0.3 1.8 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 GAM29199.1 - 0.014 15.0 0.7 0.033 13.8 0.7 1.6 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 GAM29199.1 - 0.036 13.7 0.2 3.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 GAM29199.1 - 0.045 13.3 0.2 0.073 12.6 0.2 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Acyltransferase PF01553.21 GAM29200.1 - 7.9e-24 83.8 0.0 1.5e-23 82.9 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase Pkinase_Tyr PF07714.17 GAM29201.1 - 9.8e-53 179.1 0.0 1.3e-52 178.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM29201.1 - 5e-45 153.9 0.0 1.9e-44 152.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain YL1 PF05764.13 GAM29201.1 - 0.041 14.0 10.4 0.066 13.3 10.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Pkinase_fungal PF17667.1 GAM29201.1 - 0.13 11.0 3.8 0.22 10.2 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Coat_X PF07552.11 GAM29201.1 - 0.16 11.9 0.3 0.31 10.9 0.3 1.5 1 0 0 1 1 1 0 Spore Coat Protein X and V domain Kdo PF06293.14 GAM29201.1 - 0.19 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.12 GAM29201.1 - 2.4 6.3 19.7 3.7 5.6 19.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAM29201.1 - 2.5 6.3 17.0 4.5 5.4 17.0 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GAM29201.1 - 5.8 6.2 25.7 11 5.3 25.7 1.3 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 GAM29202.1 - 6.8e-08 33.1 0.1 0.0025 18.6 0.0 4.3 3 1 1 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM29202.1 - 5e-05 23.5 0.0 0.45 10.9 0.0 4.2 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cystatin PF00031.21 GAM29203.1 - 4e-05 23.8 0.5 0.0001 22.5 0.5 1.7 1 1 0 1 1 1 1 Cystatin domain Acetyltransf_1 PF00583.25 GAM29205.1 - 7.6e-14 52.0 0.0 1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM29205.1 - 1.9e-09 37.5 0.0 2.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM29205.1 - 1.6e-08 34.9 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM29205.1 - 6.4e-08 32.5 0.0 1.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAM29205.1 - 1.2e-05 25.3 0.1 2e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAM29205.1 - 0.006 16.7 0.0 0.0081 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SPOR PF05036.13 GAM29205.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.5 1 1 0 1 1 1 0 Sporulation related domain PKD_channel PF08016.12 GAM29206.1 - 8.4e-45 153.2 19.7 8.4e-45 153.2 19.7 1.7 2 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 GAM29206.1 - 8.7e-07 28.4 29.0 8.7e-07 28.4 29.0 2.8 3 0 0 3 3 3 1 Ion transport protein PhoLip_ATPase_C PF16212.5 GAM29207.1 - 2.5e-86 289.5 26.9 2.5e-86 289.5 26.9 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAM29207.1 - 6.6e-26 89.8 4.8 6.6e-26 89.8 4.8 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 GAM29207.1 - 1.5e-13 50.6 0.0 5.2e-13 48.9 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAM29207.1 - 7.3e-12 45.2 0.0 9.9e-11 41.6 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAM29207.1 - 2.3e-07 31.3 3.6 0.00055 20.3 0.4 3.7 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAM29207.1 - 0.0026 17.6 1.8 0.0094 15.7 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2678 PF10856.8 GAM29207.1 - 0.054 13.4 0.1 15 5.6 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Ank_2 PF12796.7 GAM29209.1 - 3.7e-21 75.5 14.6 3.3e-06 27.6 0.6 4.6 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM29209.1 - 8.4e-18 64.2 10.7 0.023 15.0 0.1 8.6 5 2 4 9 9 9 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM29209.1 - 2e-16 60.1 21.0 0.0024 18.4 0.0 8.7 5 4 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM29209.1 - 1.1e-12 46.9 12.8 0.84 10.4 0.1 9.0 9 1 1 10 10 10 3 Ankyrin repeat Ank PF00023.30 GAM29209.1 - 1.5e-06 28.3 7.3 10 6.8 0.0 6.6 5 1 0 5 5 5 2 Ankyrin repeat DUF4087 PF13316.6 GAM29209.1 - 0.0087 16.5 0.0 2 8.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4087) DUF3447 PF11929.8 GAM29209.1 - 0.0089 16.0 8.2 0.38 10.7 0.0 3.9 4 1 1 5 5 5 2 Domain of unknown function (DUF3447) Acetyltransf_13 PF13880.6 GAM29211.1 - 8.2e-22 77.0 0.2 2e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 GAM29211.1 - 1.6e-11 43.8 0.5 3.1e-11 42.9 0.5 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_10 PF13673.7 GAM29211.1 - 0.0021 18.0 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM29211.1 - 0.0029 18.0 0.0 0.011 16.1 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAM29211.1 - 0.005 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ribosomal_L5_C PF00673.21 GAM29212.1 - 1.5e-21 76.4 0.0 2.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAM29212.1 - 1.5e-18 66.9 0.0 3.2e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_L22 PF00237.19 GAM29213.1 - 1.6e-36 124.7 0.7 2.2e-36 124.2 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e zf-C3HC4_3 PF13920.6 GAM29214.1 - 2.3e-07 30.6 13.2 5.3e-07 29.4 13.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAM29214.1 - 6.9e-05 23.1 17.6 0.00017 21.8 17.6 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAM29214.1 - 0.0003 20.6 13.6 0.00083 19.2 13.6 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAM29214.1 - 0.00049 19.9 16.1 0.0012 18.7 16.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAM29214.1 - 0.003 17.5 13.4 0.01 15.7 13.5 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAM29214.1 - 0.0074 16.1 16.2 0.023 14.5 16.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cys_rich_KTR PF14205.6 GAM29214.1 - 0.35 10.7 6.0 0.24 11.2 0.2 2.5 2 0 0 2 2 2 0 Cysteine-rich KTR YlbD_coat PF14071.6 GAM29214.1 - 0.54 10.5 7.9 0.75 10.1 2.3 3.1 3 0 0 3 3 3 0 Putative coat protein zf-RING_UBOX PF13445.6 GAM29214.1 - 0.56 10.3 14.9 0.98 9.5 12.4 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_10 PF16685.5 GAM29214.1 - 3.1 8.0 10.5 7.5 6.8 10.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 GAM29214.1 - 3.3 8.1 14.1 12 6.3 14.1 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain Oxidored_q6 PF01058.22 GAM29215.1 - 3.9e-22 78.5 0.3 5e-22 78.1 0.3 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Tmemb_14 PF03647.13 GAM29215.1 - 0.025 15.3 0.0 0.04 14.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane proteins 14C TIG PF01833.24 GAM29216.1 - 3e-09 36.8 19.3 4.1e-06 26.8 1.0 4.1 3 1 0 3 3 3 2 IPT/TIG domain DUF4528 PF15031.6 GAM29216.1 - 0.016 15.2 0.1 0.042 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) I-EGF_1 PF18372.1 GAM29216.1 - 0.025 14.7 1.1 0.056 13.6 1.1 1.6 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EGF_2 PF07974.13 GAM29216.1 - 0.46 10.9 3.2 1.1 9.7 3.2 1.6 1 0 0 1 1 1 0 EGF-like domain PPP4R2 PF09184.11 GAM29217.1 - 0.0081 15.8 6.4 0.016 14.8 6.4 1.4 1 0 0 1 1 1 1 PPP4R2 FAM176 PF14851.6 GAM29217.1 - 0.025 14.2 2.0 0.05 13.3 2.0 1.4 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 GAM29217.1 - 0.032 14.3 1.7 0.054 13.5 1.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Med13_C PF06333.12 GAM29217.1 - 0.082 12.2 0.8 0.11 11.8 0.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain SDA1 PF05285.12 GAM29217.1 - 0.085 12.3 3.5 0.12 11.8 3.5 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 GAM29217.1 - 0.14 11.9 8.1 0.22 11.2 8.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LAT PF15234.6 GAM29217.1 - 0.32 10.7 5.6 0.5 10.1 5.6 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells PI3K_1B_p101 PF10486.9 GAM29217.1 - 0.32 8.7 1.7 0.41 8.4 1.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.12 GAM29217.1 - 0.33 9.1 7.7 0.46 8.6 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 GAM29217.1 - 1.5 8.7 10.4 2.7 7.8 10.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 GAM29217.1 - 2.5 8.5 19.2 6.5 7.2 19.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Astro_capsid_p PF12226.8 GAM29217.1 - 3 6.9 9.5 4.6 6.3 9.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 GAM29217.1 - 8.1 5.7 18.2 12 5.1 18.2 1.2 1 0 0 1 1 1 0 NOA36 protein RhoGAP PF00620.27 GAM29218.1 - 6.5e-40 136.4 0.6 6.5e-40 136.4 0.6 2.9 2 1 1 3 3 3 1 RhoGAP domain PilJ PF13675.6 GAM29218.1 - 0.47 10.5 15.8 2.3 8.3 6.9 3.4 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Flagellin_N PF00669.20 GAM29218.1 - 7.1 6.7 11.4 8.2 6.5 5.0 3.0 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region Cpn60_TCP1 PF00118.24 GAM29219.1 - 6.3e-89 298.8 14.8 1.2e-88 297.9 14.8 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_pol_B_2 PF03175.13 GAM29220.1 - 1.9e-05 23.7 1.5 4.4e-05 22.5 1.5 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DUF1281 PF06924.11 GAM29220.1 - 0.03 13.9 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) DUF2807 PF10988.8 GAM29221.1 - 0.023 14.5 1.0 0.036 13.9 1.0 1.3 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain DUF5122 PF17164.4 GAM29221.1 - 0.45 10.8 5.0 16 5.9 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller GST_N_3 PF13417.6 GAM29222.1 - 4.2e-10 39.9 0.0 8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAM29222.1 - 2.8e-06 27.5 0.0 5.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAM29222.1 - 3e-06 27.5 0.0 6.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAM29222.1 - 7e-06 26.2 0.0 1.9e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAM29222.1 - 2e-05 24.5 0.0 6.4e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAM29222.1 - 0.00097 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAM29222.1 - 0.001 18.8 0.0 0.0066 16.2 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAM29222.1 - 0.059 14.1 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Ank_2 PF12796.7 GAM29224.1 - 0.00018 22.1 1.6 13 6.4 0.1 5.1 4 1 2 6 6 6 3 Ankyrin repeats (3 copies) Homez PF11569.8 GAM29224.1 - 0.0092 15.4 0.5 0.3 10.6 0.1 3.1 3 0 0 3 3 3 1 Homeodomain leucine-zipper encoding, Homez Ank_4 PF13637.6 GAM29224.1 - 0.08 13.6 0.5 14 6.4 0.0 4.6 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAM29225.1 - 5.9e-05 23.6 0.7 0.14 12.8 0.1 3.3 2 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM29225.1 - 0.0043 17.6 0.0 7 7.4 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) LIM PF00412.22 GAM29226.1 - 7e-23 80.6 33.0 1.3e-09 38.1 4.9 3.8 3 0 0 3 3 3 3 LIM domain DisA_N PF02457.16 GAM29226.1 - 0.064 12.8 0.0 1.8 8.1 0.0 2.8 2 1 1 3 3 3 0 DisA bacterial checkpoint controller nucleotide-binding WD40 PF00400.32 GAM29227.1 - 8.4e-63 206.8 17.3 2.3e-10 40.9 1.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM29227.1 - 2.5e-24 85.4 0.0 0.00019 21.7 0.0 6.7 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 GAM29227.1 - 1e-23 83.4 10.6 1.9e-23 82.5 10.6 1.5 1 0 0 1 1 1 1 Tup N-terminal Ge1_WD40 PF16529.5 GAM29227.1 - 1.7e-10 40.4 0.1 0.16 10.9 0.0 5.6 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAM29227.1 - 4.3e-08 32.8 0.0 0.12 11.7 0.0 5.1 5 0 0 5 5 5 2 WD40-like domain PD40 PF07676.12 GAM29227.1 - 2.6e-07 30.4 0.2 2.1 8.4 0.0 5.0 5 0 0 5 5 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 GAM29227.1 - 5e-06 26.5 0.0 0.058 13.3 0.0 3.5 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 GAM29227.1 - 4.2e-05 23.0 0.3 0.32 10.3 0.0 3.7 3 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 GAM29227.1 - 0.00016 20.4 0.3 0.0071 14.9 0.1 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain YscO-like PF16789.5 GAM29227.1 - 0.0026 17.8 1.1 0.0026 17.8 1.1 1.6 2 0 0 2 2 2 1 YscO-like protein Nup160 PF11715.8 GAM29227.1 - 0.0029 16.3 0.1 27 3.2 0.0 4.4 2 1 2 5 5 5 0 Nucleoporin Nup120/160 Frtz PF11768.8 GAM29227.1 - 0.004 15.5 0.0 1.7 6.9 0.0 3.3 2 2 2 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz SHE3 PF17078.5 GAM29227.1 - 0.019 14.7 4.8 0.031 14.0 4.8 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 LXG PF04740.12 GAM29227.1 - 0.036 13.8 2.4 0.056 13.1 2.4 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily PIN_12 PF16289.5 GAM29227.1 - 0.038 14.5 1.2 0.071 13.6 1.2 1.3 1 0 0 1 1 1 0 PIN domain Syntaxin_2 PF14523.6 GAM29227.1 - 0.04 14.3 1.6 0.081 13.3 1.6 1.5 1 0 0 1 1 1 0 Syntaxin-like protein Spc7 PF08317.11 GAM29227.1 - 0.041 12.8 3.8 0.069 12.0 3.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 GAM29227.1 - 0.064 12.6 6.2 0.085 12.2 4.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Proteasome_A_N PF10584.9 GAM29227.1 - 0.12 12.1 7.0 81 3.0 0.0 5.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Cob_adeno_trans PF01923.18 GAM29227.1 - 0.15 12.2 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase FliJ PF02050.16 GAM29227.1 - 0.22 11.7 6.8 0.52 10.5 6.8 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein Phe_tRNA-synt_N PF02912.18 GAM29227.1 - 0.23 11.4 2.5 11 6.0 0.0 2.9 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF5122 PF17164.4 GAM29227.1 - 0.38 11.1 5.7 16 5.9 0.0 5.4 7 0 0 7 7 6 0 Domain of unknown function (DUF5122) beta-propeller TMPIT PF07851.13 GAM29227.1 - 0.7 9.1 2.1 1.1 8.5 2.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein zf-C4H2 PF10146.9 GAM29227.1 - 2.1 8.6 5.5 3.5 7.9 5.5 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Golgin_A5 PF09787.9 GAM29227.1 - 4.1 6.8 11.7 0.062 12.7 4.7 1.4 2 0 0 2 2 1 0 Golgin subfamily A member 5 ABC2_membrane PF01061.24 GAM29228.1 - 6.3e-79 264.3 50.0 3.3e-43 147.6 22.9 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 GAM29228.1 - 4.4e-44 150.3 0.0 6.1e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_assoc PF08370.11 GAM29228.1 - 4.1e-09 36.1 2.2 1.4e-05 24.7 0.6 2.9 2 0 0 2 2 2 2 Plant PDR ABC transporter associated AAA_18 PF13238.6 GAM29228.1 - 1.2e-07 32.3 0.0 0.0019 18.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAM29228.1 - 4.2e-07 30.5 0.0 0.045 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GAM29228.1 - 4.8e-07 29.4 0.3 0.0024 17.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain PDR_CDR PF06422.12 GAM29228.1 - 3.2e-06 27.0 0.9 0.0044 16.9 0.1 3.1 2 0 0 2 2 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 GAM29228.1 - 3.4e-06 27.1 1.1 0.00041 20.3 0.3 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 GAM29228.1 - 6.6e-06 26.3 0.0 0.066 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 GAM29228.1 - 6.7e-06 26.1 0.1 0.016 15.2 0.0 2.8 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_21 PF13304.6 GAM29228.1 - 1.1e-05 25.5 0.0 0.41 10.4 0.1 3.5 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAM29228.1 - 5.9e-05 23.4 0.0 0.3 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAM29228.1 - 0.00036 20.2 0.2 0.89 9.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 GAM29228.1 - 0.00052 20.3 0.1 1.7 8.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 GAM29228.1 - 0.0014 18.7 0.1 0.9 9.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.6 GAM29228.1 - 0.0024 18.3 0.0 0.19 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAM29228.1 - 0.0026 17.1 0.2 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin SMC_N PF02463.19 GAM29228.1 - 0.0028 17.1 0.5 2.4 7.5 0.1 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 GAM29228.1 - 0.0041 17.0 0.2 1.2 9.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 GAM29228.1 - 0.0048 17.3 0.1 7.1 7.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAM29228.1 - 0.0074 16.7 0.1 9 6.7 0.0 3.2 3 0 0 3 3 2 0 RNA helicase Cytidylate_kin PF02224.18 GAM29228.1 - 0.012 15.4 0.0 0.41 10.3 0.0 2.8 3 0 0 3 3 3 0 Cytidylate kinase AAA_23 PF13476.6 GAM29228.1 - 0.013 16.0 0.1 0.041 14.4 0.1 1.9 2 0 0 2 2 1 0 AAA domain Ploopntkinase3 PF18751.1 GAM29228.1 - 0.016 15.1 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Roc PF08477.13 GAM29228.1 - 0.037 14.3 0.8 44 4.3 0.1 3.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 GAM29228.1 - 0.037 13.7 0.1 4.4 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 GAM29228.1 - 0.053 13.8 0.0 1.7 8.9 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KTI12 PF08433.10 GAM29228.1 - 0.072 12.5 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_14 PF13173.6 GAM29228.1 - 0.077 13.0 0.0 20 5.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAM29228.1 - 0.083 12.9 0.5 16 5.5 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 GAM29228.1 - 0.11 11.7 0.4 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 GAM29228.1 - 0.13 11.8 0.6 0.5 9.9 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 GAM29228.1 - 0.13 11.9 0.1 3.3 7.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain dNK PF01712.19 GAM29228.1 - 0.14 12.0 0.1 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 GAM29228.1 - 0.27 11.2 0.9 20 5.1 0.1 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 GAM29228.1 - 0.8 9.2 3.6 3.7 7.0 0.0 3.0 4 0 0 4 4 3 0 P-loop containing dynein motor region ABC2_membrane_3 PF12698.7 GAM29228.1 - 2.8 7.0 51.9 0.017 14.3 19.2 3.7 2 2 1 3 3 3 0 ABC-2 family transporter protein ANAPC4_WD40 PF12894.7 GAM29229.1 - 0.00011 22.5 0.1 0.8 10.1 0.0 3.7 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 GAM29229.1 - 0.00039 20.4 0.0 1.7 8.7 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.15 GAM29229.1 - 0.0051 16.2 0.1 0.27 10.5 0.0 2.1 2 0 0 2 2 2 2 CPSF A subunit region Ge1_WD40 PF16529.5 GAM29229.1 - 0.052 12.5 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 GAM29229.1 - 0.1 13.5 3.9 12 6.9 0.0 4.0 6 0 0 6 6 6 0 WD domain, G-beta repeat PLDc_2 PF13091.6 GAM29230.1 - 1.5e-35 121.9 0.1 2.3e-19 69.6 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc_3 PF13918.6 GAM29230.1 - 3.6e-35 121.2 0.7 3.6e-30 104.9 0.2 2.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAM29230.1 - 1.9e-09 37.3 0.5 0.00012 22.1 0.2 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif ATG13 PF10033.9 GAM29231.1 - 1.2e-14 54.7 12.3 1.2e-14 54.6 0.2 3.2 3 1 0 3 3 3 2 Autophagy-related protein 13 SOG2 PF10428.9 GAM29232.1 - 0.093 11.9 52.8 0.14 11.4 52.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF936 PF06075.12 GAM29232.1 - 1.6 7.6 29.6 1.8 7.3 29.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) HATPase_c PF02518.26 GAM29236.1 - 3.5e-09 37.2 0.0 7.4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPX PF03105.19 GAM29236.1 - 6.6e-07 29.6 7.7 0.0033 17.4 7.7 2.5 1 1 0 1 1 1 1 SPX domain Ctr PF04145.15 GAM29236.1 - 0.028 15.1 15.4 2.7 8.6 0.2 4.4 3 1 0 3 3 3 0 Ctr copper transporter family Connexin PF00029.19 GAM29236.1 - 0.36 10.6 11.2 20 4.8 0.0 3.9 4 0 0 4 4 4 0 Connexin DUF4698 PF15769.5 GAM29236.1 - 1.2 8.1 9.5 4 6.4 9.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Neur_chan_memb PF02932.16 GAM29236.1 - 2.1 8.4 14.2 4.6 7.2 0.1 3.3 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region TMEM51 PF15345.6 GAM29236.1 - 5.2 6.8 18.0 14 5.5 0.0 3.9 4 0 0 4 4 4 0 Transmembrane protein 51 Response_reg PF00072.24 GAM29237.1 - 1.1e-05 25.6 0.2 1.7e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Ank_2 PF12796.7 GAM29238.1 - 4e-15 56.2 2.7 4.5e-06 27.2 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM29238.1 - 7.1e-12 45.6 2.4 0.00026 21.5 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM29238.1 - 8.2e-11 41.2 2.0 0.0053 17.2 0.1 5.6 5 0 0 5 5 5 2 Ankyrin repeat VPS9 PF02204.18 GAM29238.1 - 1.9e-08 34.4 0.0 4.8e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 GAM29238.1 - 1.7e-07 31.4 2.2 0.066 13.5 0.2 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAM29238.1 - 3.5e-06 27.2 9.6 0.081 13.4 0.2 5.6 5 1 0 5 5 5 3 Ankyrin repeat Glyco_hydro_3 PF00933.21 GAM29239.1 - 1.1e-64 218.9 0.0 1.4e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAM29239.1 - 5.7e-45 153.8 0.0 8.6e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 GAM29239.1 - 2e-11 43.8 0.0 4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain GTP_EFTU PF00009.27 GAM29241.1 - 4e-58 196.2 0.3 4e-58 196.2 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAM29241.1 - 2.2e-15 56.4 0.0 7.1e-15 54.8 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 GAM29241.1 - 7.5e-10 38.8 0.3 4e-09 36.5 0.1 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 GAM29241.1 - 3.1e-09 37.1 0.1 1.3e-08 35.1 0.1 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 GAM29241.1 - 5.3e-06 26.2 0.1 6.4e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV IBR PF01485.21 GAM29242.1 - 3.6e-17 62.3 39.3 1.7e-10 41.0 8.0 3.5 3 1 0 3 3 3 3 IBR domain, a half RING-finger domain VP_N-CPKC PF11475.8 GAM29242.1 - 1.2 9.1 12.2 0.82 9.6 1.3 3.1 2 1 0 2 2 2 0 Virion protein N terminal domain Abhydro_lipase PF04083.16 GAM29243.1 - 1e-23 82.6 0.0 1.9e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 GAM29243.1 - 1.8e-12 47.4 0.9 1e-08 35.2 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAM29243.1 - 0.0044 16.3 0.0 0.036 13.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF4228 PF14009.6 GAM29243.1 - 0.052 13.9 0.0 0.085 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) AIG1 PF04548.16 GAM29244.1 - 0.00094 18.6 0.6 0.0012 18.2 0.6 1.1 1 0 0 1 1 1 1 AIG1 family zf-MYND PF01753.18 GAM29245.1 - 1.9e-06 27.8 18.9 4e-06 26.8 18.9 1.6 1 0 0 1 1 1 1 MYND finger SKN1 PF03935.15 GAM29245.1 - 0.003 16.0 2.5 0.0053 15.2 2.5 1.3 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) zf-FLZ PF04570.14 GAM29245.1 - 0.13 11.8 4.5 0.39 10.2 4.5 1.8 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Hira PF07569.11 GAM29245.1 - 0.15 11.7 7.5 0.49 10.1 7.5 1.9 1 0 0 1 1 1 0 TUP1-like enhancer of split Presenilin PF01080.17 GAM29245.1 - 0.64 8.7 7.0 1.5 7.5 7.0 1.5 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 GAM29245.1 - 1.9 8.0 24.6 3.5 7.2 6.4 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FNIP PF05725.12 GAM29246.1 - 3.3e-23 81.6 23.5 0.0072 16.5 0.1 9.4 6 3 4 10 10 10 9 FNIP Repeat FNIP PF05725.12 GAM29247.1 - 8.2e-47 157.1 19.1 1.1e-05 25.5 0.1 9.9 7 2 1 9 9 9 9 FNIP Repeat DUF538 PF04398.12 GAM29247.1 - 0.44 11.0 1.5 1.8e+02 2.6 0.0 4.4 3 2 1 4 4 4 0 Protein of unknown function, DUF538 FNIP PF05725.12 GAM29248.1 - 2.1e-22 79.0 34.9 5.7e-07 29.6 0.7 9.4 5 3 5 10 10 10 7 FNIP Repeat SdrG_C_C PF10425.9 GAM29248.1 - 0.084 13.0 7.1 0.098 12.7 3.1 2.8 1 1 1 2 2 2 0 C-terminus of bacterial fibrinogen-binding adhesin HiaBD2 PF15403.6 GAM29248.1 - 1.8 9.0 9.5 0.35 11.3 1.9 2.5 2 0 0 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) PAXNEB PF05625.11 GAM29249.1 - 1.6e-93 313.8 0.0 1.9e-93 313.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Rad51 PF08423.11 GAM29249.1 - 0.12 11.6 0.1 0.27 10.4 0.1 1.6 2 0 0 2 2 2 0 Rad51 DnaJ PF00226.31 GAM29250.1 - 7.6e-18 64.4 0.2 1.8e-17 63.2 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain zinc_ribbon_4 PF13717.6 GAM29250.1 - 0.0031 17.4 3.7 1.1 9.3 0.3 2.6 2 0 0 2 2 2 2 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 GAM29250.1 - 0.073 13.0 0.2 0.18 11.8 0.2 1.7 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Zn_ribbon_SprT PF17283.2 GAM29250.1 - 0.66 9.9 3.2 1.4 8.9 3.2 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_jaz PF12171.8 GAM29251.1 - 5.2e-07 29.8 0.3 9.3e-07 29.0 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAM29251.1 - 5.8e-06 26.5 0.7 1.1e-05 25.7 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Allexi_40kDa PF05549.11 GAM29251.1 - 0.002 17.7 4.2 0.0031 17.1 4.2 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein zf-U1 PF06220.12 GAM29251.1 - 0.12 12.2 0.3 0.22 11.3 0.3 1.4 1 0 0 1 1 1 0 U1 zinc finger GIDA_assoc PF13932.6 GAM29251.1 - 2.7 8.1 16.5 6.1 7.0 15.8 1.8 2 0 0 2 2 2 0 GidA associated domain XRN_M PF17846.1 GAM29251.1 - 7 5.5 14.5 9.8 5.0 14.5 1.2 1 0 0 1 1 1 0 Xrn1 helical domain DUF5523 PF17661.1 GAM29251.1 - 9.7 5.8 30.5 1.7 8.3 26.5 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5523) MitMem_reg PF13012.6 GAM29252.1 - 0.2 12.1 7.7 0.29 11.6 7.1 1.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function TMPIT PF07851.13 GAM29252.1 - 1.1 8.4 18.1 0.43 9.8 7.8 2.1 1 1 1 2 2 2 0 TMPIT-like protein SLATT_6 PF18169.1 GAM29252.1 - 1.4 8.5 4.9 0.66 9.6 2.3 1.7 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 Med9 PF07544.13 GAM29252.1 - 3.3 7.9 20.7 4.9 7.3 6.0 3.4 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 KxDL PF10241.9 GAM29252.1 - 3.8 7.8 19.0 0.09 13.1 5.4 3.6 3 2 3 6 6 6 0 Uncharacterized conserved protein DUF1664 PF07889.12 GAM29252.1 - 4.5 7.3 16.1 0.039 14.0 4.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 GAM29252.1 - 4.9 7.1 14.2 1.4 8.8 4.3 2.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor V_ATPase_I PF01496.19 GAM29252.1 - 7.7 4.3 12.4 10 3.9 12.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec2p PF06428.11 GAM29252.1 - 8.4 6.4 20.9 0.053 13.5 6.6 3.4 2 1 3 5 5 5 0 GDP/GTP exchange factor Sec2p FYVE PF01363.21 GAM29253.1 - 4.4e-19 68.4 7.2 5.5e-19 68.1 7.2 1.1 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 GAM29253.1 - 4.5e-05 23.6 4.8 5e-05 23.5 4.8 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger HypA PF01155.19 GAM29253.1 - 0.041 13.9 5.8 0.086 12.9 5.8 1.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 GAM29253.1 - 0.14 12.3 11.6 0.48 10.6 11.9 1.7 1 1 1 2 2 2 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 GAM29253.1 - 0.49 10.5 7.4 4.7 7.4 7.4 2.4 1 1 0 1 1 1 0 Zinc ribbon domain IBR PF01485.21 GAM29253.1 - 0.57 10.5 11.8 3.8 7.8 11.8 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 GAM29253.1 - 0.58 10.4 10.1 2.3 8.5 10.1 1.9 1 1 0 1 1 1 0 B-box zinc finger zinc_ribbon_4 PF13717.6 GAM29253.1 - 0.68 9.9 10.7 31 4.6 10.7 2.9 1 1 0 1 1 1 0 zinc-ribbon domain DUF2688 PF10892.8 GAM29253.1 - 8.5 5.9 11.7 5.2 6.6 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) TPR_1 PF00515.28 GAM29254.1 - 2.8e-21 74.4 15.3 1.1e-05 25.1 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAM29254.1 - 3.6e-19 67.3 10.7 0.0026 17.8 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAM29254.1 - 1e-18 65.9 21.3 0.00011 22.1 0.0 10.3 11 0 0 11 11 11 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM29254.1 - 4.3e-14 52.5 29.0 6.3e-13 48.8 1.2 5.8 5 2 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 GAM29254.1 - 5.8e-13 47.9 0.2 0.00047 20.0 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAM29254.1 - 2e-11 44.0 1.3 4.5e-07 30.1 0.3 7.6 7 3 3 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAM29254.1 - 1e-10 41.1 6.0 0.00034 20.2 0.0 5.6 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 GAM29254.1 - 3.7e-10 40.3 0.0 2.7e-05 24.7 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM29254.1 - 2.9e-09 37.0 0.4 0.44 11.5 0.0 5.7 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAM29254.1 - 3.4e-09 36.3 1.5 0.0086 15.9 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAM29254.1 - 9.8e-09 35.0 8.0 0.12 12.8 0.0 8.1 10 1 0 10 10 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAM29254.1 - 2.6e-07 31.1 0.1 0.086 13.4 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_3 PF07720.12 GAM29254.1 - 2.1e-06 27.6 1.6 0.0053 16.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAM29254.1 - 8.5e-05 23.0 7.7 0.28 11.9 0.0 6.0 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAM29254.1 - 0.0021 17.3 8.1 0.35 10.1 0.1 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat ANAPC8 PF04049.13 GAM29254.1 - 0.0026 17.8 14.3 0.09 12.8 0.2 3.8 3 1 1 4 4 4 2 Anaphase promoting complex subunit 8 / Cdc23 MIT PF04212.18 GAM29254.1 - 0.055 13.5 1.4 15 5.7 0.0 4.3 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain SIX1_SD PF16878.5 GAM29254.1 - 0.1 13.2 0.2 0.1 13.2 0.2 4.2 3 2 2 5 5 5 0 Transcriptional regulator, SIX1, N-terminal SD domain TPR_4 PF07721.14 GAM29254.1 - 0.5 11.2 1.6 3.3 8.6 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat PLAC8 PF04749.17 GAM29255.1 - 2.6e-14 54.0 18.8 3.3e-14 53.7 18.8 1.2 1 0 0 1 1 1 1 PLAC8 family Pkinase PF00069.25 GAM29256.1 - 2.9e-55 187.5 0.0 5.2e-55 186.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM29256.1 - 9.1e-49 166.1 0.0 1.4e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM29256.1 - 0.00043 19.2 5.0 0.00088 18.2 0.1 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 GAM29256.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_membrane PF00664.23 GAM29257.1 - 5.8e-129 429.6 22.9 1.8e-65 221.4 7.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAM29257.1 - 1e-69 233.3 0.0 2e-33 115.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAM29257.1 - 1.2e-15 57.6 0.0 6.2e-07 29.1 0.0 3.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 GAM29257.1 - 6.1e-08 31.9 1.6 0.0031 16.4 0.2 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 GAM29257.1 - 1.5e-06 28.2 0.0 0.058 13.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAM29257.1 - 9.2e-06 26.0 0.0 0.3 11.3 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAM29257.1 - 1.3e-05 24.8 1.7 0.13 12.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 GAM29257.1 - 0.00014 22.1 3.1 0.82 9.9 0.2 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit GPDPase_memb PF10110.9 GAM29257.1 - 0.00067 18.5 1.5 0.00067 18.5 1.5 2.5 3 0 0 3 3 3 1 Membrane domain of glycerophosphoryl diester phosphodiesterase AAA_7 PF12775.7 GAM29257.1 - 0.0015 18.0 0.0 2.6 7.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 GAM29257.1 - 0.0016 18.8 1.4 1.1 9.7 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain SR-25 PF10500.9 GAM29257.1 - 0.0078 15.8 14.2 0.0078 15.8 14.2 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF2057 PF09829.9 GAM29257.1 - 0.01 16.0 0.6 1.5 8.9 0.4 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) G-alpha PF00503.20 GAM29257.1 - 0.011 15.0 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit AAA_21 PF13304.6 GAM29257.1 - 0.017 14.9 0.4 19 5.0 0.2 4.0 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 GAM29257.1 - 0.019 14.7 3.8 6.9 6.4 0.1 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_5 PF07728.14 GAM29257.1 - 0.059 13.4 0.8 31 4.5 0.0 3.8 4 1 1 5 5 5 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 GAM29257.1 - 0.18 11.7 1.1 5.1 7.0 0.0 3.2 4 0 0 4 4 3 0 Adenylylsulphate kinase Roc PF08477.13 GAM29257.1 - 0.31 11.3 1.8 24 5.2 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 GAM29257.1 - 0.32 10.6 1.5 9.7 5.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 GAM29257.1 - 1.4 9.5 4.5 25 5.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF2953 PF11167.8 GAM29257.1 - 7.4 6.7 6.8 5 7.3 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) SAM_1 PF00536.30 GAM29259.1 - 0.022 15.2 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Mnd1 PF03962.15 GAM29260.1 - 0.15 12.3 0.5 21 5.5 0.1 2.7 2 0 0 2 2 2 0 Mnd1 HTH domain Dicty_REP PF05086.12 GAM29260.1 - 6.6 4.6 36.2 0.2 9.6 8.2 2.4 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DUF4461 PF14688.6 GAM29261.1 - 0.041 13.7 0.1 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) DnaJ PF00226.31 GAM29262.1 - 4.9e-06 26.6 0.2 1.2e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain M_domain PF12938.7 GAM29262.1 - 0.033 14.0 23.8 0.051 13.4 23.8 1.2 1 0 0 1 1 1 0 M domain of GW182 Androgen_recep PF02166.16 GAM29262.1 - 0.034 13.0 11.3 0.044 12.6 11.3 1.1 1 0 0 1 1 1 0 Androgen receptor Spo7 PF03907.13 GAM29262.1 - 0.068 12.6 0.2 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Spo7-like protein CENP-B_dimeris PF09026.10 GAM29262.1 - 0.14 12.5 6.5 0.31 11.5 5.6 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Peroxin-3 PF04882.12 GAM29262.1 - 0.2 10.6 7.9 0.28 10.1 7.9 1.1 1 0 0 1 1 1 0 Peroxin-3 Spt20 PF12090.8 GAM29262.1 - 0.42 10.2 24.3 0.054 13.1 19.7 1.7 2 0 0 2 2 2 0 Spt20 family Ndc1_Nup PF09531.10 GAM29262.1 - 0.93 8.1 5.7 1.3 7.6 5.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cwf_Cwc_15 PF04889.12 GAM29262.1 - 1.2 8.8 15.0 1.9 8.2 15.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PGA2 PF07543.12 GAM29262.1 - 1.3 9.0 8.6 2.3 8.2 8.6 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Presenilin PF01080.17 GAM29262.1 - 4.4 6.0 9.2 6 5.5 9.2 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 GAM29262.1 - 6.4 6.0 13.0 9.4 5.5 13.0 1.2 1 0 0 1 1 1 0 NOA36 protein DUF5550 PF17704.1 GAM29267.1 - 0.047 13.8 5.9 0.08 13.1 5.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5550) Spt20 PF12090.8 GAM29267.1 - 0.11 12.1 8.4 0.16 11.6 8.4 1.2 1 0 0 1 1 1 0 Spt20 family CCDC53 PF10152.9 GAM29267.1 - 0.86 10.0 5.8 1.4 9.4 5.8 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Connexin PF00029.19 GAM29267.1 - 4 7.1 5.7 5 6.8 5.7 1.1 1 0 0 1 1 1 0 Connexin DUF3464 PF11947.8 GAM29267.1 - 4.5 7.0 7.6 7 6.4 7.6 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Retrotrans_gag PF03732.17 GAM29268.1 - 0.00016 21.9 0.0 0.0004 20.6 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 GAM29268.1 - 0.00051 20.6 0.0 0.0025 18.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 GAM29268.1 - 0.00066 19.9 0.0 0.0023 18.2 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 GAM29268.1 - 0.0028 18.2 0.0 0.0069 16.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotran_gag_2 PF14223.6 GAM29268.1 - 0.032 13.9 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 GAM29268.1 - 0.14 12.3 0.4 0.31 11.2 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Integrase_H2C2 PF17921.1 GAM29270.1 - 7.3e-16 58.0 4.6 2.8e-15 56.2 4.6 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GAM29270.1 - 3.4e-09 36.9 0.0 7.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GAM29270.1 - 0.0071 16.5 1.3 0.12 12.7 0.1 2.6 2 0 0 2 2 2 1 H2C2 zinc finger YqfQ PF14181.6 GAM29271.1 - 2.5 8.3 4.9 3.3 7.9 4.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein TPR_15 PF13429.6 GAM29273.1 - 5.4e-06 25.8 1.5 0.00018 20.8 0.4 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAM29273.1 - 6.1e-06 26.4 3.4 0.066 13.5 0.2 4.5 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAM29273.1 - 7.3e-06 25.6 1.0 0.46 10.4 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAM29273.1 - 7.5e-06 25.7 0.6 2.5 8.5 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAM29273.1 - 6.6e-05 23.3 7.7 0.025 15.1 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAM29273.1 - 0.00022 21.4 2.5 1.2 9.5 0.1 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SOG2 PF10428.9 GAM29273.1 - 0.0021 17.3 11.2 0.0042 16.3 11.2 1.4 1 0 0 1 1 1 1 RAM signalling pathway protein TPR_8 PF13181.6 GAM29273.1 - 0.0037 17.4 0.8 39 4.8 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAM29273.1 - 0.0044 16.7 0.2 5.3 6.8 0.1 3.7 3 0 0 3 3 3 1 TPR repeat TPR_20 PF14561.6 GAM29273.1 - 0.0047 17.2 3.4 12 6.3 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAM29273.1 - 0.0071 17.0 0.0 0.36 11.5 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAM29273.1 - 0.01 16.6 0.3 2.2 9.3 0.0 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAM29273.1 - 0.02 15.5 3.1 4.1 8.2 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAM29273.1 - 0.034 14.2 0.0 9.2 6.6 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 GAM29273.1 - 0.035 13.8 2.1 0.09 12.5 0.9 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain Miga PF10265.9 GAM29273.1 - 0.061 12.3 5.3 0.1 11.6 5.3 1.4 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 GAM29273.1 - 0.21 10.1 6.6 0.3 9.6 6.6 1.3 1 0 0 1 1 1 0 Macoilin family DUF627 PF04781.12 GAM29273.1 - 0.63 10.1 4.5 0.99 9.5 0.6 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF627) GCOM2 PF15328.6 GAM29273.1 - 1.1 9.6 6.8 2.2 8.6 6.8 1.4 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 PAP1 PF08601.10 GAM29273.1 - 5.8 6.5 16.4 9 5.9 16.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 MAP65_ASE1 PF03999.12 GAM29273.1 - 6.8 5.3 7.5 11 4.5 7.5 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MFS_1 PF07690.16 GAM29274.1 - 3.5e-34 118.3 20.1 8.8e-34 117.0 20.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAM29274.1 - 8.3e-11 41.4 10.5 8.3e-11 41.4 10.5 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAM29274.1 - 0.0025 16.3 0.5 0.0025 16.3 0.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 GAM29274.1 - 0.0085 15.0 8.3 0.035 13.0 0.3 3.2 2 1 1 3 3 3 2 MFS_1 like family COX5B PF01215.19 GAM29275.1 - 5.8e-13 48.7 0.0 6.8e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 GAM29275.1 - 0.014 15.5 1.7 0.021 14.8 1.7 1.3 1 0 0 1 1 1 0 Zinc-finger domain CDC27 PF09507.10 GAM29276.1 - 0.14 11.6 29.0 0.2 11.0 29.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 OST3_OST6 PF04756.13 GAM29278.1 - 0.032 13.6 0.2 0.032 13.6 0.2 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Pkinase PF00069.25 GAM29279.1 - 4.2e-74 249.2 2.7 5.6e-74 248.8 0.1 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM29279.1 - 1.9e-34 119.2 0.0 3.3e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM29279.1 - 1e-07 31.6 0.0 1.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAM29279.1 - 2.9e-05 23.1 0.0 2.9e-05 23.1 0.0 3.3 2 1 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 GAM29279.1 - 3.7e-05 23.2 0.0 7.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 GAM29279.1 - 6.5e-05 22.0 0.1 0.00012 21.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 GAM29279.1 - 0.00043 20.3 0.0 0.0077 16.2 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 GAM29279.1 - 0.067 12.7 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RAMP4 PF06624.12 GAM29279.1 - 1.5 8.9 4.1 13 5.9 0.0 3.5 3 0 0 3 3 3 0 Ribosome associated membrane protein RAMP4 adh_short PF00106.25 GAM29280.1 - 2.3e-31 108.8 0.0 2.6e-30 105.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAM29280.1 - 3.8e-15 56.1 0.0 4.2e-14 52.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAM29280.1 - 2.5e-06 27.5 0.0 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 GAM29280.1 - 0.0011 19.2 0.0 0.0076 16.5 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ISPD_C PF18706.1 GAM29280.1 - 0.051 13.2 0.5 0.092 12.4 0.5 1.4 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain FNIP PF05725.12 GAM29281.1 - 3e-48 161.7 9.1 3e-14 52.9 0.4 5.5 5 0 0 5 5 5 5 FNIP Repeat LMWPc PF01451.21 GAM29282.1 - 2.2e-34 118.9 0.1 2.6e-33 115.4 0.1 2.0 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase eIF3_subunit PF08597.10 GAM29283.1 - 0.087 12.7 11.6 0.9 9.4 3.7 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF4611 PF15387.6 GAM29283.1 - 0.75 10.1 13.0 0.82 9.9 3.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 GAM29283.1 - 1.3 9.4 11.3 2.3 8.6 4.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 GAM29283.1 - 1.4 8.2 11.9 2.1 7.6 0.7 2.1 2 0 0 2 2 2 0 NOA36 protein DUF4551 PF15087.6 GAM29283.1 - 3.9 6.2 4.9 4.6 6.0 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) F_actin_bund_C PF18060.1 GAM29284.1 - 6.4e-20 71.1 0.7 1.2e-19 70.1 0.7 1.5 1 0 0 1 1 1 1 F actin bundling C terminal Sec23_helical PF04815.15 GAM29284.1 - 0.076 12.9 0.1 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 Sec23/Sec24 helical domain EF-hand_5 PF13202.6 GAM29284.1 - 0.12 12.0 0.0 0.33 10.5 0.0 1.8 1 0 0 1 1 1 0 EF hand Peptidase_C1 PF00112.23 GAM29285.1 - 2.9e-74 249.8 3.6 4.3e-74 249.3 3.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 GAM29285.1 - 4.5e-13 49.4 6.6 4.5e-13 49.4 6.6 1.8 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 GAM29285.1 - 0.00065 18.6 2.1 0.0097 14.7 0.3 2.3 2 0 0 2 2 2 2 Peptidase C1-like family PIN_6 PF17146.4 GAM29286.1 - 2.1e-26 92.2 1.9 5.7e-26 90.8 0.2 2.5 2 0 0 2 2 2 1 PIN domain of ribonuclease DUF2457 PF10446.9 GAM29286.1 - 1.1e-05 24.8 22.6 1.1e-05 24.8 22.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Androgen_recep PF02166.16 GAM29286.1 - 0.47 9.2 14.9 1 8.1 14.9 1.6 1 0 0 1 1 1 0 Androgen receptor Macoilin PF09726.9 GAM29286.1 - 0.48 8.9 25.0 0.079 11.5 5.3 2.1 2 0 0 2 2 2 0 Macoilin family Ecl1 PF12855.7 GAM29286.1 - 1.9 9.7 30.2 3.6 8.7 3.7 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Mucin PF01456.17 GAM29286.1 - 2 8.4 43.4 0.47 10.4 26.5 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Acyl-CoA_dh_1 PF00441.24 GAM29287.1 - 1.8e-42 145.1 0.1 3.1e-42 144.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAM29287.1 - 8.9e-40 135.9 0.0 1.7e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAM29287.1 - 1.7e-28 98.7 0.2 3.4e-28 97.7 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAM29287.1 - 1e-13 51.7 0.0 3.4e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAM29287.1 - 0.0025 17.5 0.1 0.011 15.4 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Pox_LP_H2 PF03356.15 GAM29287.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Viral late protein H2 ALG3 PF05208.13 GAM29288.1 - 3.9e-53 181.2 31.9 6.8e-53 180.3 31.9 1.3 1 0 0 1 1 1 1 ALG3 protein Me-amine-dh_H PF06433.11 GAM29288.1 - 0.019 13.9 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) ERG4_ERG24 PF01222.17 GAM29289.1 - 1.2e-97 327.4 20.9 1.4e-97 327.2 20.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 GAM29289.1 - 0.029 13.9 2.4 0.038 13.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) HSP70 PF00012.20 GAM29290.1 - 4.5e-125 418.1 3.5 5.9e-125 417.8 3.5 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAM29290.1 - 7.8e-08 31.5 1.8 0.0086 14.9 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 GAM29290.1 - 9.8e-05 22.2 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4824 PF16106.5 GAM29290.1 - 0.099 11.9 0.0 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4824) Y_phosphatase2 PF03162.13 GAM29291.1 - 2.1e-42 144.5 0.0 3.7e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GAM29291.1 - 0.0024 17.9 0.0 0.0053 16.7 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Spore-coat_CotD PF11122.8 GAM29291.1 - 0.032 15.0 3.7 0.039 14.8 2.4 1.8 1 1 1 2 2 2 0 Inner spore coat protein D RhoGEF PF00621.20 GAM29292.1 - 1.2e-36 126.7 6.1 1.2e-36 126.7 6.1 1.8 2 0 0 2 2 2 1 RhoGEF domain TFIIA PF03153.13 GAM29292.1 - 0.74 9.7 18.2 0.093 12.7 13.3 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CH PF00307.31 GAM29293.1 - 5e-41 139.3 0.0 4.3e-19 68.7 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain Cortex-I_coil PF09304.10 GAM29293.1 - 3e-38 130.3 19.1 3e-38 130.3 19.1 2.8 4 0 0 4 4 4 1 Cortexillin I, coiled coil CAMSAP_CH PF11971.8 GAM29293.1 - 1e-06 28.5 0.0 0.0003 20.6 0.0 2.8 2 1 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 GAM29293.1 - 0.0096 16.0 1.6 0.38 10.9 0.0 3.3 3 1 0 3 3 3 1 CH-like domain in sperm protein Filament PF00038.21 GAM29293.1 - 0.41 10.2 21.1 0.028 14.0 11.8 2.3 1 1 1 2 2 2 0 Intermediate filament protein GvpG PF05120.12 GAM29293.1 - 5.6 7.0 10.6 0.43 10.6 4.6 2.2 2 0 0 2 2 2 0 Gas vesicle protein G SapB_2 PF03489.17 GAM29294.1 - 7.3e-43 144.4 22.0 1.4e-09 37.9 0.0 5.9 5 0 0 5 5 5 5 Saposin-like type B, region 2 SapB_1 PF05184.15 GAM29294.1 - 4.3e-27 93.7 23.4 1.5e-07 31.3 0.2 6.1 5 0 0 5 5 5 5 Saposin-like type B, region 1 LPD11 PF18824.1 GAM29294.1 - 0.1 12.7 0.0 6.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 Picorna_P3A PF06363.11 GAM29294.1 - 0.53 10.2 5.0 1.1 9.1 0.2 3.6 4 0 0 4 4 4 0 Picornaviridae P3A protein FNIP PF05725.12 GAM29295.1 - 1.9e-30 104.7 1.6 2.1e-09 37.4 0.0 3.5 2 1 1 3 3 3 3 FNIP Repeat LRR_5 PF13306.6 GAM29295.1 - 0.036 14.0 0.1 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Rubredoxin_C PF18267.1 GAM29296.1 - 0.022 14.7 0.1 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 Rubredoxin NAD+ reductase C-terminal domain Tudor_2 PF18104.1 GAM29296.1 - 0.083 12.6 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain SdrD_B PF17210.3 GAM29297.1 - 6.4e-05 23.2 2.8 0.013 15.7 0.2 2.6 2 0 0 2 2 2 2 SdrD B-like domain Bt_P21 PF05560.11 GAM29297.1 - 0.096 12.3 0.6 7.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacillus thuringiensis P21 molecular chaperone protein SpaA PF17802.1 GAM29297.1 - 0.13 12.6 0.2 0.13 12.6 0.2 2.2 2 1 0 2 2 2 0 Prealbumin-like fold domain FAM76 PF16046.5 GAM29298.1 - 7.1 5.9 10.1 12 5.2 5.9 2.3 2 0 0 2 2 2 0 FAM76 protein RNA_pol_Rpb5_C PF01191.19 GAM29299.1 - 9.5e-34 115.1 0.7 2.1e-33 114.0 0.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 GAM29299.1 - 4.9e-22 78.3 0.5 1.6e-21 76.7 0.0 2.0 2 1 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.14 GAM29299.1 - 0.024 14.9 1.2 0.044 14.1 1.2 1.4 1 0 0 1 1 1 0 Sof1-like domain ENTH PF01417.20 GAM29300.1 - 3.5e-43 146.6 0.0 5.4e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 GAM29300.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 ANTH domain Sec7 PF01369.20 GAM29301.1 - 5.8e-42 143.4 0.3 8.5e-42 142.9 0.3 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 GAM29301.1 - 1.1e-19 70.9 1.1 1.9e-19 70.1 1.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 GAM29301.1 - 9.9e-06 25.9 1.8 1.8e-05 25.1 1.8 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAM29301.1 - 0.0032 17.7 1.5 0.085 13.1 1.5 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Myosin_TH1 PF06017.13 GAM29301.1 - 0.055 13.1 0.6 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding PH_9 PF15410.6 GAM29301.1 - 0.17 12.3 1.2 5.8 7.3 1.2 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain MIT PF04212.18 GAM29302.1 - 1.8e-44 149.6 16.0 2e-17 63.0 2.7 3.2 3 0 0 3 3 3 3 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 GAM29302.1 - 0.0032 17.5 8.3 0.83 9.9 0.3 5.0 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAM29302.1 - 0.011 15.8 1.5 11 6.3 0.1 3.7 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM29302.1 - 0.014 15.2 9.0 0.42 10.5 0.3 4.9 4 1 2 6 6 6 0 Tetratricopeptide repeat Ferritin PF00210.24 GAM29302.1 - 0.017 15.1 0.5 0.056 13.4 0.5 1.9 1 0 0 1 1 1 0 Ferritin-like domain BTAD PF03704.17 GAM29302.1 - 0.031 14.7 0.6 0.24 11.8 0.2 2.4 3 0 0 3 3 3 0 Bacterial transcriptional activator domain BRO1 PF03097.18 GAM29302.1 - 0.038 12.8 4.6 0.94 8.2 0.1 2.6 3 0 0 3 3 3 0 BRO1-like domain TPR_8 PF13181.6 GAM29302.1 - 0.077 13.2 1.8 28 5.2 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat HEPN_AbiV PF18728.1 GAM29302.1 - 0.15 12.2 1.7 1 9.5 0.1 2.4 2 0 0 2 2 2 0 AbiV TPR_12 PF13424.6 GAM29302.1 - 0.27 11.5 4.5 3.6 8.0 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat NAD_binding_2 PF03446.15 GAM29303.1 - 4.2e-53 179.7 0.3 5.9e-53 179.3 0.3 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAM29303.1 - 3.4e-32 111.3 0.0 5.9e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 GAM29303.1 - 4.4e-09 35.9 0.0 7.3e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAM29303.1 - 6.5e-09 36.3 0.1 1.7e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 GAM29303.1 - 1.4e-06 28.0 0.1 2.3e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 GAM29303.1 - 4.3e-06 26.4 0.5 0.00021 21.0 0.2 2.4 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 GAM29303.1 - 1.7e-05 24.8 0.2 7.5e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 GAM29303.1 - 0.00023 20.8 0.0 0.001 18.7 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 GAM29303.1 - 0.0012 19.1 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain PDH PF02153.17 GAM29303.1 - 0.0018 17.3 0.2 0.0024 16.9 0.2 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase Shikimate_DH PF01488.20 GAM29303.1 - 0.015 15.3 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DpaA_N PF16924.5 GAM29303.1 - 0.018 15.1 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain OCD_Mu_crystall PF02423.15 GAM29303.1 - 0.019 13.9 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 GAM29303.1 - 0.058 14.2 0.2 0.21 12.4 0.1 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 GAM29303.1 - 0.12 12.8 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Oxysterol_BP PF01237.18 GAM29304.1 - 7.6e-60 202.7 3.9 4.1e-58 197.0 0.1 2.4 2 1 1 3 3 3 2 Oxysterol-binding protein Flavokinase PF01687.17 GAM29305.1 - 3.5e-30 104.5 0.0 4.6e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase DUF2524 PF10732.9 GAM29305.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) BRO1 PF03097.18 GAM29306.1 - 5.2e-105 351.4 11.3 5.2e-105 351.4 11.3 2.1 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GAM29306.1 - 1.7e-72 244.2 20.1 1.7e-72 244.2 20.1 2.5 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF4473 PF14747.6 GAM29306.1 - 0.37 11.4 5.7 30 5.2 0.5 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) KxDL PF10241.9 GAM29306.1 - 0.48 10.7 12.4 0.13 12.5 2.2 3.9 3 0 0 3 3 3 0 Uncharacterized conserved protein LIM PF00412.22 GAM29307.1 - 1.2e-29 102.3 40.6 2.6e-11 43.6 4.7 3.2 3 0 0 3 3 3 3 LIM domain WH2 PF02205.20 GAM29308.1 - 8.6e-09 35.0 0.2 1.6e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 WH2 motif Thymosin PF01290.20 GAM29308.1 - 0.004 16.8 0.1 0.0072 16.0 0.1 1.4 1 0 0 1 1 1 1 Thymosin beta-4 family Pkinase PF00069.25 GAM29309.1 - 2.5e-61 207.4 0.0 4.2e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM29309.1 - 3.6e-48 164.1 0.0 5.7e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM29309.1 - 0.00058 18.8 2.7 0.0028 16.5 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase SMYLE_N PF18615.1 GAM29309.1 - 9.2 5.7 11.1 14 5.1 11.1 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Ras PF00071.22 GAM29310.1 - 1.3e-34 119.1 0.2 1.6e-34 118.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAM29310.1 - 6.6e-26 90.9 0.1 1e-25 90.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAM29310.1 - 4.4e-08 32.8 0.1 4.9e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAM29310.1 - 5.4e-06 25.9 0.2 6.8e-06 25.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 GAM29310.1 - 0.0043 16.3 1.0 0.07 12.3 0.1 2.3 1 1 1 2 2 2 1 G-protein alpha subunit DLIC PF05783.11 GAM29310.1 - 0.0098 14.8 0.3 2.4 6.9 0.1 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.9 GAM29310.1 - 0.02 14.7 0.3 0.045 13.5 0.3 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 GAM29310.1 - 0.056 12.8 0.0 1.4 8.3 0.0 2.3 2 1 1 3 3 3 0 Bacterial TniB protein SRPRB PF09439.10 GAM29310.1 - 0.067 12.6 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAM29310.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Robl_LC7 PF03259.17 GAM29311.1 - 7.8e-09 35.2 0.1 2e-08 33.9 0.1 1.6 1 1 0 1 1 1 1 Roadblock/LC7 domain PseudoU_synth_1 PF01416.20 GAM29312.1 - 9.5e-15 55.0 0.0 2.2e-10 41.0 0.0 3.0 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF2344 PF10105.9 GAM29312.1 - 0.0029 17.5 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) Alk_phosphatase PF00245.20 GAM29313.1 - 2e-85 287.3 2.8 3.2e-85 286.6 2.8 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 GAM29313.1 - 5.6e-05 22.6 1.3 0.00011 21.6 0.3 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily ETRAMP PF09716.10 GAM29313.1 - 0.028 14.5 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PALP PF00291.25 GAM29314.1 - 6.7e-49 166.9 0.1 8.3e-24 84.5 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Wbp11 PF09429.10 GAM29315.1 - 2.2e-11 44.0 8.5 2.2e-11 44.0 8.5 2.2 2 0 0 2 2 2 1 WW domain binding protein 11 FoP_duplication PF13865.6 GAM29315.1 - 0.19 12.3 6.0 0.23 12.1 0.2 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 RhoGEF PF00621.20 GAM29316.1 - 5.5e-39 134.3 0.6 5.5e-39 134.3 0.6 2.3 2 1 0 2 2 2 1 RhoGEF domain PH_16 PF17838.1 GAM29316.1 - 0.0014 18.5 0.1 0.34 10.8 0.0 2.8 2 0 0 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 GAM29316.1 - 0.012 15.6 0.0 0.065 13.2 0.0 2.2 2 0 0 2 2 2 0 PH domain PH PF00169.29 GAM29316.1 - 0.023 15.2 0.2 0.91 10.1 0.2 2.9 1 1 0 1 1 1 0 PH domain PH_10 PF15411.6 GAM29316.1 - 0.028 14.7 0.7 0.097 12.9 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain SF3A3 PF16837.5 GAM29316.1 - 0.16 12.5 0.6 0.75 10.4 0.1 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DivIC PF04977.15 GAM29316.1 - 9 6.1 7.4 12 5.8 0.7 2.9 2 0 0 2 2 2 0 Septum formation initiator CH PF00307.31 GAM29317.1 - 3.6e-38 130.1 23.3 8.2e-15 54.9 0.1 6.2 6 0 0 6 6 6 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 GAM29317.1 - 2.1e-05 24.3 0.2 0.29 11.0 0.1 3.5 2 0 0 2 2 2 2 CAMSAP CH domain HAP1_N PF04849.13 GAM29317.1 - 0.00012 21.4 34.6 0.00012 21.4 34.6 6.1 2 2 4 6 6 6 2 HAP1 N-terminal conserved region CH_2 PF06294.11 GAM29317.1 - 0.0068 16.5 0.2 0.0068 16.5 0.2 3.6 4 0 0 4 4 4 1 CH-like domain in sperm protein NT-C2 PF10358.9 GAM29318.1 - 1.2e-19 70.5 2.2 3.6e-19 68.9 2.2 1.9 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.19 GAM29318.1 - 1.9e-19 69.8 2.7 7.3e-19 68.0 2.7 2.1 1 0 0 1 1 1 1 DIL domain TPR_MLP1_2 PF07926.12 GAM29318.1 - 0.002 18.2 2.8 0.002 18.2 2.8 3.2 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein TFR_dimer PF04253.15 GAM29318.1 - 0.23 11.6 3.7 0.38 10.9 1.0 2.7 2 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain ATG16 PF08614.11 GAM29318.1 - 0.84 9.8 35.8 2.8 8.1 12.8 3.3 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Nnf1 PF03980.14 GAM29318.1 - 0.97 9.8 22.1 0.91 9.9 1.9 3.8 3 0 0 3 3 3 0 Nnf1 UPF0242 PF06785.11 GAM29318.1 - 5.5 7.1 36.7 68 3.5 11.2 2.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_12 PF13087.6 GAM29319.1 - 1.5e-49 168.3 0.3 3.3e-49 167.2 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAM29319.1 - 2.9e-19 69.9 10.5 5.8e-15 55.8 0.1 3.6 3 1 1 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 GAM29319.1 - 2e-11 44.1 0.0 0.017 14.9 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2439 PF10382.9 GAM29319.1 - 3.2e-10 40.2 1.3 1.2e-09 38.4 1.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) zf-GRF PF06839.12 GAM29319.1 - 1e-08 35.1 1.5 3.1e-08 33.6 1.5 1.8 1 0 0 1 1 1 1 GRF zinc finger UvrD_C_2 PF13538.6 GAM29319.1 - 3.1e-06 26.9 0.0 9.9e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 GAM29319.1 - 2.2e-05 24.8 0.0 0.00051 20.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain ATP13 PF12921.7 GAM29319.1 - 0.055 13.3 0.2 1.1 9.1 0.1 2.8 2 0 0 2 2 2 0 Mitochondrial ATPase expression AAA_30 PF13604.6 GAM29319.1 - 0.062 13.0 0.0 0.93 9.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAM29319.1 - 0.073 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cyt-b5 PF00173.28 GAM29320.1 - 9.8e-20 70.5 0.1 1.1e-19 70.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mst1_SARAH PF11629.8 GAM29321.1 - 0.13 12.4 0.1 0.44 10.7 0.1 1.9 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Ctr PF04145.15 GAM29321.1 - 0.21 12.2 0.5 0.41 11.3 0.1 1.6 2 0 0 2 2 2 0 Ctr copper transporter family SapB_2 PF03489.17 GAM29322.1 - 0.0045 17.1 1.0 0.68 10.1 0.1 2.7 2 0 0 2 2 2 2 Saposin-like type B, region 2 SPA PF08616.10 GAM29323.1 - 1.3e-12 47.7 0.1 3.1e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 GAM29323.1 - 2.1e-08 33.3 1.6 9.6e-08 31.1 1.6 2.0 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.21 GAM29323.1 - 8.9e-06 25.8 1.1 2.8e-05 24.2 0.9 2.0 2 1 0 2 2 2 1 DENN (AEX-3) domain DUF2347 PF09804.9 GAM29323.1 - 0.0037 16.9 1.0 0.0037 16.9 1.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SpuA_C PF18033.1 GAM29324.1 - 0.026 14.6 0.3 0.03 14.4 0.3 1.2 1 0 0 1 1 1 0 SpuA C-terminal RuvA_N PF01330.21 GAM29324.1 - 0.048 13.8 0.4 0.14 12.2 0.3 1.7 1 1 1 2 2 2 0 RuvA N terminal domain GSAP-16 PF14959.6 GAM29325.1 - 1.5e-23 82.8 0.3 6e-23 80.8 0.3 2.1 1 0 0 1 1 1 1 gamma-Secretase-activating protein C-term TFIIA PF03153.13 GAM29325.1 - 0.015 15.3 23.1 0.061 13.3 11.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4820 PF16091.5 GAM29325.1 - 0.33 10.3 2.5 0.94 8.8 2.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Hydin_ADK PF17213.3 GAM29325.1 - 0.99 9.6 7.9 0.32 11.3 3.2 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Suf PF05843.14 GAM29325.1 - 9.6 6.1 11.7 0.42 10.5 2.4 2.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) WD40 PF00400.32 GAM29326.1 - 1.8e-10 41.2 10.2 0.0042 17.9 0.1 5.4 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAM29326.1 - 7.2e-05 23.0 0.1 1.6 9.1 0.0 3.7 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain RAMA PF18755.1 GAM29327.1 - 2.5e-11 43.9 0.0 7.2e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated DUF3583 PF12126.8 GAM29327.1 - 0.0098 15.4 2.4 0.0098 15.4 2.4 3.6 2 1 1 4 4 4 1 Protein of unknown function (DUF3583) Vta1 PF04652.16 GAM29328.1 - 6.4e-39 133.2 0.1 6.4e-39 133.2 0.1 3.2 3 0 0 3 3 3 1 Vta1 like Vta1_C PF18097.1 GAM29328.1 - 5.6e-13 48.3 2.2 5.6e-13 48.3 2.2 1.9 2 0 0 2 2 2 1 Vta1 C-terminal domain Presenilin PF01080.17 GAM29328.1 - 0.49 9.1 35.6 0.89 8.2 35.6 1.5 1 0 0 1 1 1 0 Presenilin Exonuc_VII_L PF02601.15 GAM29328.1 - 9.3 5.7 26.6 17 4.8 26.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit RNB PF00773.19 GAM29330.1 - 8.3e-88 294.8 0.0 1.7e-87 293.9 0.0 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GAM29330.1 - 9.1e-19 67.3 0.0 1.9e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 GAM29330.1 - 4.9e-10 39.3 0.4 1.3e-09 38.0 0.4 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 GAM29330.1 - 1.8e-08 34.4 0.3 1.6e-07 31.4 0.0 2.6 3 0 0 3 3 3 1 Cold shock domain Rrp44_S1 PF17215.3 GAM29330.1 - 0.00034 20.5 0.1 0.001 19.0 0.1 1.8 1 0 0 1 1 1 1 S1 domain Dis3l2_C_term PF17877.1 GAM29330.1 - 0.0014 18.9 0.0 0.0055 17.0 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal ATG27 PF09451.10 GAM29331.1 - 2.4e-13 50.6 0.4 2.7e-13 50.4 0.4 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 GAM29331.1 - 2.5e-10 39.9 0.4 3.4e-10 39.4 0.4 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor PRKCSH_1 PF13015.6 GAM29331.1 - 4.4e-05 23.2 0.4 5.8e-05 22.8 0.4 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein G_glu_transpept PF01019.21 GAM29331.1 - 0.19 10.4 0.2 0.25 10.1 0.2 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase TPR_2 PF07719.17 GAM29332.1 - 8.2e-27 91.1 19.1 7.7e-06 25.6 0.6 8.7 7 1 1 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.31 GAM29332.1 - 7.7e-23 80.4 15.4 5.3e-22 77.7 5.6 3.7 3 1 0 3 3 3 1 DnaJ domain TPR_1 PF00515.28 GAM29332.1 - 8.3e-22 76.0 21.7 7.7e-07 28.7 0.5 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAM29332.1 - 7.7e-19 66.3 16.6 0.00036 20.5 0.1 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAM29332.1 - 2.7e-16 59.9 2.3 0.013 16.1 0.0 6.6 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAM29332.1 - 5.2e-15 55.7 14.6 1.3e-05 25.6 0.3 6.1 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAM29332.1 - 8.4e-15 54.2 19.8 0.011 15.4 0.2 8.5 7 2 2 9 9 8 5 TPR repeat TPR_14 PF13428.6 GAM29332.1 - 1.9e-12 46.9 9.3 0.015 16.1 0.0 6.6 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAM29332.1 - 3.1e-08 33.8 9.1 1.2 9.5 0.2 6.3 5 2 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAM29332.1 - 6.9e-08 32.5 0.3 0.0049 17.0 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAM29332.1 - 2.6e-06 27.4 7.3 0.49 10.5 0.0 5.6 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 GAM29332.1 - 3.5e-06 27.5 8.4 0.079 13.4 0.1 4.0 1 1 3 4 4 4 3 Alkyl sulfatase dimerisation TPR_6 PF13174.6 GAM29332.1 - 6.2e-06 26.5 11.2 0.041 14.5 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAM29332.1 - 0.00081 19.3 4.9 5 7.4 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat BTAD PF03704.17 GAM29332.1 - 0.00094 19.6 0.9 1.3 9.5 0.0 3.8 3 2 0 3 3 3 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 GAM29332.1 - 0.00095 19.5 7.9 1.3 9.4 0.1 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 GAM29332.1 - 0.0013 17.7 1.3 0.0013 17.7 1.3 4.0 1 1 3 4 4 4 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 GAM29332.1 - 0.0015 18.7 9.7 0.048 13.9 0.1 4.6 2 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GAM29332.1 - 0.0086 15.3 15.3 0.015 14.6 0.6 4.3 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAM29332.1 - 0.029 14.7 16.9 0.097 13.1 0.2 6.1 8 0 0 8 8 5 0 Tetratricopeptide repeat GlutR_dimer PF00745.20 GAM29332.1 - 0.055 13.9 2.5 0.068 13.6 0.2 2.3 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF357 PF04010.13 GAM29332.1 - 0.23 11.5 3.6 1.5 9.0 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF357) TPR_10 PF13374.6 GAM29332.1 - 0.5 10.3 8.8 3.1 7.8 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4363 PF14276.6 GAM29332.1 - 9 6.5 13.6 1.5 9.0 0.4 4.4 5 1 0 5 5 5 0 Domain of unknown function (DUF4363) Kinesin PF00225.23 GAM29333.1 - 4.9e-62 209.8 0.1 4.9e-62 209.8 0.1 3.2 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAM29333.1 - 1.4e-15 57.5 0.1 1.6e-13 50.8 0.0 3.5 3 1 0 3 3 3 1 Microtubule binding DUF2968 PF11180.8 GAM29333.1 - 0.00039 20.1 10.3 0.00039 20.1 10.3 2.4 3 1 0 3 3 3 1 Protein of unknown function (DUF2968) Phage_GP20 PF06810.11 GAM29333.1 - 0.0011 18.8 11.3 0.0074 16.1 3.9 3.6 2 1 1 3 3 3 1 Phage minor structural protein GP20 DUF1664 PF07889.12 GAM29333.1 - 0.11 12.5 25.1 0.33 11.0 2.3 5.2 4 2 1 5 5 5 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 GAM29333.1 - 0.32 11.5 10.9 15 6.1 0.6 5.3 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein CALCOCO1 PF07888.11 GAM29333.1 - 0.34 9.7 34.3 0.0096 14.8 27.5 1.7 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4172 PF13776.6 GAM29333.1 - 0.6 10.5 3.9 3.6 8.0 0.5 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4172) Intein_splicing PF14890.6 GAM29333.1 - 0.61 10.0 3.8 9.1 6.2 0.1 2.9 2 0 0 2 2 2 0 Intein splicing domain AvrLm4-7 PF18661.1 GAM29333.1 - 1.5 9.9 4.3 29 5.8 0.6 2.8 1 1 1 2 2 2 0 Avirulence Effector AvrLm4-7 DUF5082 PF16888.5 GAM29333.1 - 3.8 7.8 34.1 0.62 10.4 10.9 4.6 2 1 3 5 5 4 0 Domain of unknown function (DUF5082) DUF2353 PF09789.9 GAM29333.1 - 4.8 6.4 30.8 0.98 8.7 10.8 2.6 2 1 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) TPR_MLP1_2 PF07926.12 GAM29333.1 - 6 6.9 30.7 4.7 7.3 19.2 3.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 GAM29333.1 - 8.2 6.6 29.5 0.55 10.4 13.7 2.9 1 1 1 2 2 2 0 Tropomyosin like Fib_alpha PF08702.10 GAM29333.1 - 8.4 6.6 34.0 0.043 14.0 6.4 4.5 3 2 0 4 4 4 0 Fibrinogen alpha/beta chain family SAM_1 PF00536.30 GAM29334.1 - 0.002 18.5 0.0 0.0048 17.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAM29334.1 - 0.025 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SET PF00856.28 GAM29335.1 - 0.026 14.9 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 SET domain Flu_M1 PF00598.19 GAM29335.1 - 0.06 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) HTH_28 PF13518.6 GAM29335.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PikAIV_N PF18605.1 GAM29336.1 - 0.076 12.6 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF5074 PF16819.5 GAM29336.1 - 0.082 13.0 0.6 0.23 11.5 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) tRNA-synt_1e PF01406.19 GAM29336.1 - 0.088 12.1 0.4 0.16 11.3 0.1 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DS PF01916.17 GAM29339.1 - 0.091 12.0 0.0 0.091 12.0 0.0 1.0 1 0 0 1 1 1 0 Deoxyhypusine synthase DUF3842 PF12953.7 GAM29341.1 - 0.086 13.2 0.0 0.17 12.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) Peptidase_C39_2 PF13529.6 GAM29343.1 - 6.4e-10 39.8 0.0 2.6e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase_C39 like family Guanylate_cyc_2 PF09778.9 GAM29343.1 - 0.00099 18.5 0.2 0.0044 16.4 0.2 2.0 1 1 0 1 1 1 1 Guanylylate cyclase Peptidase_C70 PF12385.8 GAM29343.1 - 0.035 14.1 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 GAM29343.1 - 0.077 12.8 0.1 0.14 11.9 0.0 1.4 2 0 0 2 2 2 0 Peptidase C39 family SH3BGR PF04908.15 GAM29344.1 - 2.3e-15 56.5 0.1 3.4e-15 56.0 0.1 1.3 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 GAM29344.1 - 2.1e-10 40.7 0.0 2.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 GAM29344.1 - 0.11 12.9 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RhoGAP PF00620.27 GAM29345.1 - 4.5e-36 124.0 0.3 1.4e-35 122.3 0.3 1.8 1 0 0 1 1 1 1 RhoGAP domain BAR_3 PF16746.5 GAM29345.1 - 4.1e-16 59.4 5.9 4.1e-16 59.4 5.9 2.9 3 1 1 4 4 4 1 BAR domain of APPL family BAR PF03114.18 GAM29345.1 - 7.2e-09 35.6 7.8 2e-08 34.2 7.8 1.7 1 1 0 1 1 1 1 BAR domain BAR_2 PF10455.9 GAM29345.1 - 7.7e-05 22.0 10.9 8.1e-05 21.9 9.7 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Nod1 PF17114.5 GAM29345.1 - 0.011 15.9 0.2 0.026 14.7 0.2 1.6 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 DSPc PF00782.20 GAM29346.1 - 2.7e-10 40.2 11.4 3.2e-06 27.0 0.0 3.4 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain tRNA-synt_1 PF00133.22 GAM29347.1 - 5.9e-13 47.9 0.0 6.9e-13 47.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GAM29347.1 - 4.8e-10 38.7 0.0 6e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAM29348.1 - 1.1e-36 126.3 0.0 2.5e-36 125.2 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAM29348.1 - 4.7e-13 49.4 0.6 2.9e-12 46.8 0.6 2.3 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAM29348.1 - 1.7e-08 33.6 0.2 2.9e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAM29348.1 - 7.2e-06 25.6 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain PhyH PF05721.13 GAM29349.1 - 3.2e-07 30.8 0.0 8.1e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 GAM29349.1 - 0.00082 18.2 0.4 2.9 6.6 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 GAM29349.1 - 0.0018 19.1 0.0 0.0036 18.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 GAM29349.1 - 0.029 14.8 0.0 0.13 12.7 0.0 1.9 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase NIF PF03031.18 GAM29350.1 - 2.3e-24 85.9 1.2 5.1e-24 84.8 1.2 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 GAM29350.1 - 6.1e-07 29.1 0.0 1.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 GAM29350.1 - 0.013 15.6 0.2 0.042 13.9 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain Arf PF00025.21 GAM29351.1 - 2.1e-77 258.5 0.1 2.6e-77 258.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAM29351.1 - 1.6e-14 54.2 0.0 2.3e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM29351.1 - 1.8e-14 53.6 0.0 2.1e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAM29351.1 - 1.5e-13 50.7 2.0 9.4e-10 38.2 0.5 2.6 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.22 GAM29351.1 - 2.7e-12 46.6 0.0 3e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAM29351.1 - 1.4e-11 44.2 0.0 1.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAM29351.1 - 2.5e-05 24.3 0.0 3.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAM29351.1 - 0.0052 16.1 0.8 0.026 13.9 0.4 1.9 1 1 1 2 2 2 1 6-phosphofructo-2-kinase Pkinase_Tyr PF07714.17 GAM29352.1 - 4.6e-59 199.8 0.0 6.7e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM29352.1 - 1.7e-51 175.1 0.0 2.7e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAM29352.1 - 3.6e-07 29.3 0.0 6.1e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Cbl_N2 PF02761.14 GAM29352.1 - 6.4e-06 26.8 0.1 2.4e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain SH2 PF00017.24 GAM29352.1 - 0.0004 20.4 0.0 0.00088 19.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 GAM29352.1 - 0.055 13.4 0.2 0.61 10.0 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3439 PF11921.8 GAM29352.1 - 0.064 13.2 2.1 0.14 12.1 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 GAM29352.1 - 0.14 10.3 6.3 0.2 9.8 6.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_UL25 PF01499.16 GAM29352.1 - 0.17 10.3 0.7 0.27 9.7 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Hydrolase_4 PF12146.8 GAM29353.1 - 2.2e-09 36.9 0.4 4.2e-06 26.2 0.3 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAM29353.1 - 9.6e-08 31.8 0.0 0.0041 16.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1749 PF08538.10 GAM29353.1 - 0.00023 20.3 0.0 0.00031 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.16 GAM29353.1 - 0.00025 20.9 0.7 0.032 14.1 0.0 2.8 1 1 2 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 GAM29353.1 - 0.00043 20.0 0.0 0.8 9.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 GAM29353.1 - 0.0016 18.0 0.1 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 GAM29353.1 - 0.006 17.2 0.0 0.013 16.1 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 GAM29353.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PAE PF03283.13 GAM29353.1 - 0.024 13.8 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase DUF2974 PF11187.8 GAM29353.1 - 0.047 13.3 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pterin_4a PF01329.19 GAM29354.1 - 4.7e-23 81.2 0.1 5.7e-23 80.9 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Cullin PF00888.22 GAM29355.1 - 1.7e-139 466.3 22.3 2.3e-139 465.8 22.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAM29355.1 - 2.5e-24 85.1 1.0 6.2e-24 83.8 1.0 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain RGS PF00615.19 GAM29355.1 - 0.0063 16.8 7.4 0.66 10.3 3.1 3.6 2 1 0 2 2 2 2 Regulator of G protein signaling domain Ank_2 PF12796.7 GAM29356.1 - 0.00015 22.3 0.1 0.32 11.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) DUF3447 PF11929.8 GAM29356.1 - 0.15 12.1 2.7 0.2 11.6 0.1 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) FNIP PF05725.12 GAM29357.1 - 1.7e-26 92.1 5.6 1.7e-10 40.9 0.1 5.9 4 2 0 5 5 5 4 FNIP Repeat Methyltransf_2 PF00891.18 GAM29358.1 - 9e-34 116.6 0.0 1.3e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 GAM29358.1 - 7.3e-07 29.1 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 GAM29358.1 - 0.056 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Dimerisation PF08100.11 GAM29358.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Na_H_Exchanger PF00999.21 GAM29359.1 - 6.6e-61 206.2 41.1 1e-60 205.6 41.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family BCHF PF07284.11 GAM29359.1 - 0.015 15.3 0.9 0.015 15.3 0.9 3.3 3 0 0 3 3 3 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Cytomega_UL20A PF05984.12 GAM29359.1 - 0.54 10.6 3.8 0.21 11.9 0.6 2.0 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein DFP PF04127.15 GAM29360.1 - 2e-16 60.4 0.0 3.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein RabGAP-TBC PF00566.18 GAM29361.1 - 1.1e-23 84.0 4.9 8.7e-16 58.2 0.5 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain STAC2_u1 PF16664.5 GAM29361.1 - 2 8.9 14.0 0.69 10.4 1.7 2.7 2 1 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 DUF3452 PF11934.8 GAM29362.1 - 0.088 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Clathrin PF00637.20 GAM29363.1 - 3.6e-196 642.9 60.5 3.5e-32 111.2 2.2 9.0 10 0 0 10 10 10 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 GAM29363.1 - 5.9e-39 130.5 4.9 4.9e-07 29.8 0.0 6.8 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 GAM29363.1 - 9.9e-29 99.1 2.7 1.7e-28 98.3 0.9 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 GAM29363.1 - 5.7e-12 44.8 0.5 1.6e-11 43.3 0.5 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_7 PF13176.6 GAM29363.1 - 0.0002 21.1 3.0 1.3 9.2 0.0 6.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 GAM29363.1 - 0.00033 19.8 5.6 0.62 9.0 0.8 3.7 3 0 0 3 3 3 2 Coatomer WD associated region TPR_8 PF13181.6 GAM29363.1 - 0.087 13.1 9.9 44 4.7 0.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAM29363.1 - 0.096 12.6 16.4 0.34 10.8 0.1 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat HCNGP PF07818.13 GAM29363.1 - 0.16 12.6 1.6 0.37 11.5 0.1 2.4 3 0 0 3 3 2 0 HCNGP-like protein TPR_2 PF07719.17 GAM29363.1 - 0.2 11.8 20.8 1.6 9.1 0.1 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAM29363.1 - 1 10.4 10.0 1.7e+02 3.4 0.0 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAM29363.1 - 7.9 6.8 9.6 12 6.3 0.1 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Ank_2 PF12796.7 GAM29364.1 - 2.8e-14 53.4 9.3 0.00031 21.3 0.1 6.8 3 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAM29364.1 - 5.5e-08 32.9 7.7 0.034 14.5 0.2 6.5 8 0 0 8 8 8 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAM29364.1 - 5.8e-08 33.1 3.8 7.3 7.3 0.1 8.2 7 2 2 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM29364.1 - 0.00026 21.2 6.6 12 6.9 0.0 7.4 10 0 0 10 10 10 2 Ankyrin repeat Agenet PF05641.12 GAM29367.1 - 0.0023 18.3 1.1 0.17 12.3 0.3 3.2 3 0 0 3 3 3 2 Agenet domain Hormone_recep PF00104.30 GAM29370.1 - 0.0007 19.2 0.3 0.0012 18.5 0.3 1.3 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor Plavaka PF18759.1 GAM29372.1 - 0.0038 16.5 0.0 0.0058 15.9 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase FEZ PF07763.13 GAM29372.1 - 0.0069 16.2 0.0 0.016 15.0 0.0 1.5 2 0 0 2 2 2 1 FEZ-like protein Agenet PF05641.12 GAM29373.1 - 0.00059 20.2 0.1 0.43 11.1 0.1 3.0 2 0 0 2 2 2 2 Agenet domain Tudor_3 PF18115.1 GAM29373.1 - 0.13 12.1 0.1 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain DUF1043 PF06295.12 GAM29378.1 - 0.048 13.7 0.9 0.079 13.0 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) RsgI_N PF12791.7 GAM29379.1 - 0.15 12.0 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Anti-sigma factor N-terminus DUF4542 PF15075.6 GAM29381.1 - 0.059 13.7 0.2 0.21 12.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) Pox_A22 PF04848.13 GAM29385.1 - 0.048 13.8 0.0 0.077 13.1 0.0 1.3 1 1 0 1 1 1 0 Poxvirus A22 protein Chlorosome_CsmC PF11098.8 GAM29386.1 - 0.24 11.4 8.5 0.87 9.6 8.7 1.7 1 1 1 2 2 2 0 Chlorosome envelope protein C Gemini_AL1 PF00799.20 GAM29387.1 - 0.044 14.2 0.4 0.2 12.0 0.2 2.0 1 1 1 2 2 2 0 Geminivirus Rep catalytic domain HrpE PF06188.12 GAM29388.1 - 0.11 12.4 11.1 0.65 9.8 0.1 3.2 2 1 1 3 3 3 0 HrpE/YscL/FliH and V-type ATPase subunit E Pox_A32 PF04665.12 GAM29390.1 - 3.1e-07 30.1 0.3 4.3e-07 29.6 0.3 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein Phostensin PF13914.6 GAM29390.1 - 0.1 13.3 0.4 0.16 12.6 0.4 1.3 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region YqaJ PF09588.10 GAM29392.1 - 2.6e-21 76.3 0.0 6.9e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain SR-25 PF10500.9 GAM29392.1 - 2.9 7.5 14.8 5.1 6.6 14.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 GAM29392.1 - 7 4.6 15.6 9.6 4.1 15.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein dNK PF01712.19 GAM29393.1 - 5.8e-08 32.8 0.0 8.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase PGA2 PF07543.12 GAM29395.1 - 2.6 8.0 9.8 0.26 11.3 2.3 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Slu7 PF11708.8 GAM29395.1 - 3.5 7.3 11.3 0.11 12.2 5.0 1.6 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor TFIIF_alpha PF05793.12 GAM29395.1 - 4.6 5.7 15.5 0.16 10.6 6.2 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FGF-BP1 PF06473.12 GAM29396.1 - 0.057 13.3 0.8 0.091 12.6 0.8 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) TPALS PF18178.1 GAM29399.1 - 0.023 14.2 0.2 0.055 12.9 0.1 1.6 2 0 0 2 2 2 0 TIR- and PNP-associating SLOG family PDDEXK_7 PF04411.12 GAM29399.1 - 0.03 14.3 0.6 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily EF-hand_2 PF09068.11 GAM29399.1 - 0.075 13.2 0.4 0.2 11.8 0.2 1.8 2 0 0 2 2 2 0 EF hand SLT_2 PF13406.6 GAM29399.1 - 0.1 11.8 0.9 0.85 8.8 0.1 2.1 2 0 0 2 2 2 0 Transglycosylase SLT domain YedD PF13987.6 GAM29399.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 YedD-like protein Sporozoite_P67 PF05642.11 GAM29401.1 - 4.4 5.3 10.4 6.5 4.7 10.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Agenet PF05641.12 GAM29403.1 - 0.022 15.2 0.5 0.082 13.4 0.1 2.0 2 0 0 2 2 2 0 Agenet domain Tudor-knot PF11717.8 GAM29403.1 - 0.092 12.6 0.7 0.21 11.5 0.7 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Macoilin PF09726.9 GAM29403.1 - 0.3 9.6 1.2 0.37 9.3 1.2 1.1 1 0 0 1 1 1 0 Macoilin family DDE_Tnp_4 PF13359.6 GAM29404.1 - 0.00011 21.9 0.1 0.0002 21.1 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease BUD22 PF09073.10 GAM29404.1 - 0.00023 20.7 6.1 0.00029 20.3 6.1 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 GAM29404.1 - 0.13 10.4 15.2 0.16 10.2 15.2 1.0 1 0 0 1 1 1 0 Nop14-like family Pes-10 PF07149.11 GAM29404.1 - 0.53 9.3 6.1 0.7 8.9 6.1 1.4 1 0 0 1 1 1 0 Pes-10 SDA1 PF05285.12 GAM29404.1 - 3.6 6.9 13.1 4.3 6.7 13.1 1.3 1 0 0 1 1 1 0 SDA1 RT_RNaseH_2 PF17919.1 GAM29406.1 - 1.2e-38 131.2 0.0 2.6e-38 130.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAM29406.1 - 2.9e-38 130.4 0.0 5.8e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAM29406.1 - 5.1e-31 107.9 1.0 9.3e-31 107.1 1.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 GAM29406.1 - 3.4e-20 71.9 0.3 6.9e-20 70.9 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GAM29406.1 - 1.5e-12 47.7 0.0 3.2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 GAM29406.1 - 3.3e-07 30.4 0.0 3.2e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger UPF0181 PF03701.14 GAM29406.1 - 0.042 13.5 0.3 0.1 12.2 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) rve_3 PF13683.6 GAM29406.1 - 0.099 12.4 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Get5_C PF18514.1 GAM29406.1 - 0.47 10.2 1.4 39 4.1 0.1 2.9 3 0 0 3 3 3 0 Get5 C-terminal domain DUF1091 PF06477.13 GAM29408.1 - 0.12 12.9 0.7 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) Leader_CPA1 PF08252.11 GAM29408.1 - 0.21 11.0 0.6 0.43 10.0 0.6 1.4 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide Pro_isomerase PF00160.21 GAM29410.1 - 6.3e-48 163.0 0.2 6.3e-48 163.0 0.2 1.8 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SAPS PF04499.15 GAM29410.1 - 0.55 9.0 6.2 0.69 8.6 6.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4551 PF15087.6 GAM29410.1 - 0.71 8.6 4.9 0.86 8.4 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF913 PF06025.12 GAM29410.1 - 4.6 6.1 7.8 8.1 5.3 7.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GAM29410.1 - 5.9 5.5 15.0 7.8 5.1 15.0 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 GAM29410.1 - 9.1 6.0 13.9 15 5.3 13.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Bystin PF05291.11 GAM29411.1 - 2.4e-117 391.4 1.4 2.4e-117 391.4 1.4 2.0 2 0 0 2 2 2 1 Bystin SRI PF08236.11 GAM29411.1 - 0.93 9.7 0.0 0.93 9.7 0.0 2.6 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain XRN_N PF03159.18 GAM29412.1 - 1.6e-17 63.7 6.2 1.3e-13 50.9 0.1 2.6 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 GAM29412.1 - 0.0015 17.6 2.9 0.04 12.9 0.0 2.8 3 0 0 3 3 3 2 Xrn1 helical domain DUF3439 PF11921.8 GAM29412.1 - 0.029 14.3 5.2 0.061 13.3 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TP53IP5 PF15331.6 GAM29412.1 - 0.12 12.5 2.8 0.23 11.6 2.8 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 GTP_EFTU PF00009.27 GAM29413.1 - 5.2e-32 111.0 2.7 5.2e-32 111.0 2.7 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAM29413.1 - 1.6e-17 63.5 1.1 5.3e-17 61.9 0.0 2.5 3 0 0 3 3 3 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 GAM29413.1 - 5.3e-09 36.2 0.3 3e-08 33.7 0.2 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 GAM29413.1 - 2.3e-06 27.3 0.1 5e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.25 GAM29413.1 - 5.1e-06 26.8 1.5 5.1e-06 26.8 1.5 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 GAM29413.1 - 4.4e-05 23.3 2.4 0.00024 21.0 1.5 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 4 FeoB_N PF02421.18 GAM29413.1 - 0.00016 21.3 0.2 0.00041 19.9 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 GAM29413.1 - 0.0002 21.5 0.1 0.0002 21.5 0.1 2.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAM29413.1 - 0.00066 19.2 0.1 0.00066 19.2 0.1 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 GAM29413.1 - 0.021 14.8 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 GAM29413.1 - 0.4 10.7 13.5 1.3 9.1 0.0 4.1 3 1 1 4 4 4 0 Dynamin family MDM10 PF12519.8 GAM29413.1 - 5.6 5.7 15.5 1.4 7.7 8.5 2.3 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 Pkinase PF00069.25 GAM29415.1 - 8.4e-45 153.2 4.8 7.8e-41 140.2 0.0 2.4 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAM29415.1 - 1.5e-34 119.5 0.0 5.7e-33 114.3 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM29415.1 - 3.2e-05 22.9 1.4 5.6e-05 22.1 1.4 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAM29415.1 - 3.9e-05 23.1 0.2 0.0001 21.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DUF2722 PF10846.8 GAM29415.1 - 0.0036 16.3 4.8 0.004 16.2 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 GAM29415.1 - 0.07 12.7 11.5 0.09 12.4 11.5 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 GAM29415.1 - 0.22 11.5 7.4 0.24 11.3 7.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 GAM29416.1 - 1.1e-50 172.5 0.1 1.3e-50 172.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM29416.1 - 1.8e-35 122.5 0.0 2.2e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM29416.1 - 9.5e-08 31.2 0.2 1.2e-07 30.9 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAM29416.1 - 1e-05 25.1 0.0 2.3e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAM29416.1 - 0.0061 15.9 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5030 PF16433.5 GAM29416.1 - 0.049 13.0 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5030) Malate_synthase PF01274.22 GAM29417.1 - 1.4e-207 690.2 0.0 1.5e-207 690.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Peptidase_C1_2 PF03051.15 GAM29417.1 - 0.061 12.1 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase C1-like family HpcH_HpaI PF03328.14 GAM29417.1 - 0.16 11.1 0.0 0.47 9.6 0.0 1.8 2 1 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Acetyltransf_1 PF00583.25 GAM29418.1 - 3e-13 50.0 0.0 3.9e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAM29418.1 - 8.5e-09 35.4 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAM29418.1 - 1.4e-06 28.6 0.0 2.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAM29418.1 - 9.6e-05 22.3 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Cyt-b5 PF00173.28 GAM29419.1 - 1.6e-21 76.2 0.1 2.3e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain adh_short PF00106.25 GAM29420.1 - 3.9e-11 42.8 0.1 8.5e-07 28.6 0.0 2.9 2 1 1 3 3 3 2 short chain dehydrogenase KR PF08659.10 GAM29420.1 - 0.0057 16.6 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAM29420.1 - 0.0093 15.1 0.0 2.2 7.3 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein YkuD_2 PF13645.6 GAM29420.1 - 0.036 13.5 0.1 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 L,D-transpeptidase catalytic domain Orthopox_B11R PF07033.11 GAM29420.1 - 0.057 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Orthopoxvirus B11R protein CBF_beta PF02312.17 GAM29422.1 - 9.9e-05 22.0 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Core binding factor beta subunit Acyl-CoA_dh_N PF02771.16 GAM29422.1 - 0.18 12.4 0.0 0.24 12.1 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain CENP-F_leu_zip PF10473.9 GAM29423.1 - 0.003 17.6 9.8 0.003 17.6 9.8 7.7 2 2 4 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LIM PF00412.22 GAM29424.1 - 1.5e-21 76.3 30.8 1.1e-07 32.0 6.4 3.7 3 0 0 3 3 3 3 LIM domain C1_1 PF00130.22 GAM29424.1 - 0.008 16.0 20.8 0.24 11.3 2.3 3.7 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) XAF1_C PF18608.1 GAM29424.1 - 0.013 15.1 7.0 0.97 9.0 0.1 3.5 3 0 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain Endonuclea_NS_2 PF13930.6 GAM29424.1 - 0.034 14.3 2.5 2 8.5 0.2 2.7 2 1 0 2 2 2 0 DNA/RNA non-specific endonuclease DUF3716 PF12511.8 GAM29424.1 - 0.096 12.7 19.5 0.67 10.0 1.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3716) Mut7-C PF01927.16 GAM29424.1 - 2.1 8.5 18.7 3.3 7.8 2.5 3.5 3 0 0 3 3 3 0 Mut7-C RNAse domain MTHFR_C PF12225.8 GAM29424.1 - 6.1 6.6 22.4 2.8 7.6 0.8 4.4 3 3 1 4 4 4 0 Methylene-tetrahydrofolate reductase C terminal Dishevelled PF02377.15 GAM29424.1 - 6.4 7.2 10.2 1.8 9.0 2.5 2.9 2 1 1 3 3 3 0 Dishevelled specific domain LIM PF00412.22 GAM29425.1 - 4.8e-22 78.0 19.3 1.4e-12 47.6 8.4 2.6 2 0 0 2 2 2 2 LIM domain PH PF00169.29 GAM29425.1 - 1.7e-07 31.7 0.0 7.4e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 PH domain Citrate_synt PF00285.21 GAM29426.1 - 5.7e-136 453.3 0.0 7.6e-136 452.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Sod_Cu PF00080.20 GAM29427.1 - 8.3e-48 162.2 3.7 9.7e-48 161.9 3.7 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SLATT_5 PF18160.1 GAM29428.1 - 2.5 7.4 8.0 1.1 8.6 4.5 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 FadA PF09403.10 GAM29428.1 - 5.5 7.5 11.7 0.45 11.0 3.4 3.0 1 1 2 3 3 3 0 Adhesion protein FadA Pkinase PF00069.25 GAM29429.1 - 1.7e-73 247.2 0.0 4.5e-73 245.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAM29429.1 - 2.7e-46 157.9 0.0 4.4e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAM29429.1 - 7.9e-07 28.7 0.1 1.2e-05 24.8 0.0 2.4 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 GAM29429.1 - 0.00041 19.2 0.0 0.00089 18.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAM29429.1 - 0.0022 18.0 0.0 0.033 14.1 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family PI3K_P85_iSH2 PF16454.5 GAM29429.1 - 0.0032 17.1 3.2 0.0032 17.1 3.2 1.6 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4988 PF16378.5 GAM29429.1 - 0.035 13.8 0.6 0.16 11.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function Kdo PF06293.14 GAM29429.1 - 0.046 13.1 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAM29429.1 - 0.056 12.5 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 V-SNARE PF05008.15 GAM29430.1 - 5.7e-06 26.6 1.9 5.7e-06 26.6 1.9 2.3 1 1 1 2 2 2 2 Vesicle transport v-SNARE protein N-terminus Pox_A14 PF05767.12 GAM29430.1 - 0.08 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Peptidase_M28 PF04389.17 GAM29433.1 - 5.3e-25 88.3 0.1 8.4e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAM29433.1 - 3.8e-07 30.0 0.0 9.6e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 GAM29433.1 - 0.03 13.8 0.1 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 Nicastrin MerB PF03243.15 GAM29433.1 - 0.41 10.8 1.5 3.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Alkylmercury lyase DUF2362 PF10154.9 GAM29434.1 - 2e-11 43.5 9.0 2e-11 43.5 9.0 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2362) Rad51 PF08423.11 GAM29434.1 - 0.081 12.2 1.3 0.85 8.8 0.6 2.1 1 1 1 2 2 2 0 Rad51 DUF364 PF04016.12 GAM29434.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation Topoisom_I_N PF02919.15 GAM29434.1 - 3.3 7.1 7.2 4.2 6.8 6.7 1.4 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment COX6C PF02937.15 GAM29436.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc MRP-L47 PF06984.13 GAM29437.1 - 2.5e-21 75.6 0.2 6.3e-21 74.3 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 GAM29437.1 - 1.4e-10 40.9 1.2 4.1e-10 39.5 1.2 1.8 1 0 0 1 1 1 1 Ribosomal L29 protein PBD PF00786.28 GAM29438.1 - 3.7e-06 27.2 0.9 4.8e-05 23.6 0.0 3.6 2 0 0 2 2 2 1 P21-Rho-binding domain Tropomyosin PF00261.20 GAM29438.1 - 0.0022 17.4 10.9 0.0022 17.4 10.9 6.5 2 2 5 7 7 7 4 Tropomyosin ODR4-like PF14778.6 GAM29439.1 - 4.7e-59 200.2 3.3 4.7e-59 200.2 3.3 1.5 2 0 0 2 2 2 1 Olfactory receptor 4-like Spt20 PF12090.8 GAM29439.1 - 0.0096 15.6 10.4 0.0096 15.6 10.4 2.9 3 0 0 3 3 3 1 Spt20 family Orf78 PF06024.12 GAM29439.1 - 0.015 15.6 3.8 0.52 10.6 0.1 2.5 2 0 0 2 2 2 0 Orf78 (ac78) Hep_59 PF07052.11 GAM29439.1 - 0.18 12.6 11.8 0.064 14.0 3.5 3.0 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 DUF4448 PF14610.6 GAM29439.1 - 0.23 11.2 0.1 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF5383 PF17355.2 GAM29439.1 - 0.67 10.3 8.2 1.5 9.2 0.5 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5383) TMEM51 PF15345.6 GAM29439.1 - 1.1 9.0 8.1 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 Suf PF05843.14 GAM29439.1 - 3.2 7.7 13.4 0.6 10.1 4.0 2.6 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) UCR_6-4kD PF08997.10 GAM29440.1 - 3.2e-05 23.8 0.0 4.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.9 GAM29440.1 - 0.00029 20.8 2.4 0.0021 18.1 2.4 2.0 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) RRM_2 PF04059.12 GAM29441.1 - 1.7e-29 101.8 0.5 3.4e-29 100.9 0.5 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 GAM29441.1 - 0.00064 19.5 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 GAM29441.1 - 0.0027 17.7 10.2 0.011 15.7 10.2 2.1 1 1 0 1 1 1 1 Smg-4/UPF3 family Androgen_recep PF02166.16 GAM29442.1 - 0.18 10.6 4.7 0.18 10.6 4.7 1.2 1 0 0 1 1 1 0 Androgen receptor SUIM_assoc PF16619.5 GAM29442.1 - 0.41 10.8 11.1 0.52 10.4 11.1 1.5 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 GAM29442.1 - 3.2 7.7 11.7 3.5 7.5 11.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP PF05725.12 GAM29443.1 - 2.3e-29 101.3 16.3 7.7e-10 38.8 2.3 4.8 5 0 0 5 5 5 4 FNIP Repeat FNIP PF05725.12 GAM29444.1 - 1e-81 268.8 17.4 6.8e-11 42.2 0.2 7.7 1 1 8 10 10 10 10 FNIP Repeat ParBc_2 PF08857.11 GAM29444.1 - 0.23 11.6 1.8 2.1e+02 1.9 0.0 5.2 1 1 3 6 6 6 0 Putative ParB-like nuclease LAL_C2 PF18603.1 GAM29446.1 - 0.2 11.8 0.0 0.21 11.7 0.0 1.1 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 DnaJ PF00226.31 GAM29447.1 - 4.2e-06 26.8 0.2 1.2e-05 25.4 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain BUD22 PF09073.10 GAM29447.1 - 0.00011 21.6 4.5 0.00014 21.4 4.5 1.2 1 0 0 1 1 1 1 BUD22 SUIM_assoc PF16619.5 GAM29447.1 - 0.0023 18.0 20.8 0.0088 16.1 0.6 2.5 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GAM29447.1 - 0.0024 17.5 21.3 0.0024 17.5 21.3 1.7 2 0 0 2 2 2 1 Spt20 family Spo7 PF03907.13 GAM29447.1 - 0.017 14.6 0.3 0.46 9.9 0.1 2.1 2 0 0 2 2 2 0 Spo7-like protein CENP-B_dimeris PF09026.10 GAM29447.1 - 0.019 15.3 9.6 0.019 15.3 9.6 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 GAM29447.1 - 0.02 14.6 19.0 0.034 13.9 19.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF913 PF06025.12 GAM29447.1 - 0.022 13.8 3.8 0.032 13.2 3.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ASD2 PF08687.11 GAM29447.1 - 0.022 14.3 5.5 0.033 13.7 5.5 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Spc7_N PF15402.6 GAM29447.1 - 0.089 11.0 13.5 0.11 10.7 13.5 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Ndc1_Nup PF09531.10 GAM29447.1 - 0.095 11.4 5.4 0.1 11.3 5.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SLC12 PF03522.15 GAM29447.1 - 0.13 11.3 7.1 0.17 10.9 7.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 MscS_TM PF12794.7 GAM29447.1 - 0.16 10.8 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 M_domain PF12938.7 GAM29447.1 - 0.18 11.6 28.0 0.26 11.1 28.0 1.2 1 0 0 1 1 1 0 M domain of GW182 UPF0524 PF15823.5 GAM29447.1 - 0.3 10.4 9.5 0.47 9.8 9.5 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 NPR3 PF03666.13 GAM29447.1 - 0.36 9.6 9.8 0.46 9.2 9.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CNDH2_M PF16869.5 GAM29447.1 - 0.73 10.5 19.1 1.3 9.7 19.1 1.4 1 0 0 1 1 1 0 PF16858 Zip PF02535.22 GAM29447.1 - 1.1 8.3 4.8 1.5 8.0 4.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SURF2 PF05477.11 GAM29447.1 - 1.3 8.6 12.8 2.1 8.0 12.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Androgen_recep PF02166.16 GAM29447.1 - 1.7 7.4 21.9 2.1 7.1 21.9 1.1 1 0 0 1 1 1 0 Androgen receptor DUF775 PF05603.12 GAM29447.1 - 3.1 7.3 10.2 0.57 9.7 6.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Presenilin PF01080.17 GAM29447.1 - 3.3 6.4 12.7 4.4 6.0 12.7 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 GAM29447.1 - 3.7 6.8 16.1 5.5 6.2 16.1 1.2 1 0 0 1 1 1 0 NOA36 protein Herpes_DNAp_acc PF04929.12 GAM29447.1 - 4.6 6.1 8.3 6 5.7 8.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor BRF1 PF07741.13 GAM29447.1 - 5 7.5 9.4 8 6.9 8.2 1.9 1 1 0 1 1 1 0 Brf1-like TBP-binding domain DivIC PF04977.15 GAM29447.1 - 9.6 6.1 14.2 23 4.8 14.2 1.6 1 0 0 1 1 1 0 Septum formation initiator Hid1 PF12722.7 GAM29447.1 - 9.8 4.2 11.7 12 3.8 11.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_hydro_18 PF00704.28 GAM29448.1 - 1.5e-19 70.9 2.6 2e-19 70.5 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Voltage_CLC PF00654.20 GAM29449.1 - 9.7e-97 324.4 27.1 1.4e-96 323.8 23.9 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 GAM29449.1 - 8.4e-11 42.1 0.2 4.4e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain TAT_signal PF10518.9 GAM29449.1 - 0.00094 18.9 2.4 0.00094 18.9 2.4 2.4 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 GAM29449.1 - 0.013 14.8 2.1 0.043 13.2 2.1 1.8 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF373 PF04123.13 GAM29449.1 - 9.3 5.6 12.0 0.51 9.7 6.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF373) LIM PF00412.22 GAM29450.1 - 7.7e-11 42.1 5.8 1.2e-10 41.4 5.8 1.3 1 0 0 1 1 1 1 LIM domain NinD PF17466.2 GAM29450.1 - 0.14 12.2 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function Gaa1 PF04114.14 GAM29451.1 - 1.3e-40 139.9 22.4 3.2e-40 138.6 19.7 2.7 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component CDC45 PF02724.14 GAM29451.1 - 0.046 12.0 1.1 0.065 11.5 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.7 GAM29452.1 - 2.1e-39 134.0 2.9 1.6e-08 35.0 0.1 5.7 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAM29452.1 - 1.7e-35 120.9 8.4 2.2e-06 28.1 0.1 8.0 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 GAM29452.1 - 3e-29 100.2 13.3 9.6e-05 22.7 0.0 9.3 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 GAM29452.1 - 4.8e-25 87.3 4.4 2.8e-05 24.3 0.0 7.3 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAM29452.1 - 1.3e-18 65.1 9.3 0.066 13.8 0.1 9.1 10 0 0 10 10 10 6 Ankyrin repeat BTB PF00651.31 GAM29452.1 - 7.9e-16 58.3 0.7 0.0037 17.5 0.0 4.8 4 0 0 4 4 4 4 BTB/POZ domain SPX PF03105.19 GAM29452.1 - 0.0047 16.9 18.4 0.0047 16.9 18.4 2.4 2 0 0 2 2 2 1 SPX domain DUF2572 PF10833.8 GAM29452.1 - 1.6 8.4 5.6 4.4 7.0 5.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) zinc_ribbon_15 PF17032.5 GAM29453.1 - 4.4e-10 40.2 0.1 8.4e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 zinc-ribbon family Lar_restr_allev PF14354.6 GAM29453.1 - 0.026 14.9 0.1 0.056 13.8 0.1 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Baculo_ME53 PF06061.11 GAM29453.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 zf-ribbon_3 PF13248.6 GAM29453.1 - 0.26 10.7 3.9 4.4 6.9 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF2116 PF09889.9 GAM29453.1 - 7.3 6.7 6.9 0.29 11.2 0.5 2.1 2 1 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PBD PF00786.28 GAM29456.1 - 3.5e-06 27.3 0.0 1.4e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain PRCC PF10253.9 GAM29456.1 - 7 7.4 34.0 0.13 13.1 9.2 2.5 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Med13_C PF06333.12 GAM29456.1 - 8 5.6 32.2 6 6.0 13.1 2.4 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain MRP-L47 PF06984.13 GAM29457.1 - 2.5e-21 75.6 0.2 6.1e-21 74.3 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 GAM29457.1 - 1.4e-10 41.0 1.2 4e-10 39.5 1.2 1.8 1 0 0 1 1 1 1 Ribosomal L29 protein COX6C PF02937.15 GAM29458.1 - 0.085 13.0 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc DUF2362 PF10154.9 GAM29460.1 - 1.1e-66 225.8 1.5 5.1e-35 121.4 0.0 2.0 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2362) TFIIA PF03153.13 GAM29461.1 - 0.13 12.2 11.7 0.18 11.8 11.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GxGYxYP_N PF16216.5 GAM29464.1 - 0.0094 16.1 0.2 0.021 15.0 0.2 1.6 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal SK_channel PF03530.14 GAM29465.1 - 1.5e-05 24.9 2.2 5.6e-05 23.1 2.2 2.0 1 1 0 1 1 1 1 Calcium-activated SK potassium channel 2TM PF13239.6 GAM29465.1 - 5.7 7.3 10.0 5.7 7.3 0.7 3.3 3 1 0 3 3 3 0 2TM domain IF-2B PF01008.17 GAM29466.1 - 6.1e-72 242.2 0.0 7.1e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family LRR_4 PF12799.7 GAM29467.1 - 0.0011 19.3 16.0 0.019 15.4 1.2 5.5 4 1 1 6 6 6 2 Leucine Rich repeats (2 copies) ASH PF15780.5 GAM29467.1 - 0.084 13.1 4.7 0.29 11.4 4.7 2.0 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin LRR_9 PF14580.6 GAM29467.1 - 0.13 11.8 0.2 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 GAM29468.1 - 8.9e-05 22.3 3.7 0.057 13.5 0.0 5.0 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 GAM29468.1 - 0.012 16.0 0.0 0.012 16.0 0.0 5.6 5 2 1 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAM29468.1 - 0.74 10.6 3.3 8.7 7.3 0.1 4.3 3 2 0 3 3 3 0 Leucine Rich Repeat HATPase_c PF02518.26 GAM29470.1 - 2.4e-29 102.1 0.2 5.8e-29 100.9 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAM29470.1 - 3e-23 82.1 0.1 1.2e-22 80.2 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAM29470.1 - 1.4e-13 50.6 0.1 1.4e-12 47.5 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 GAM29470.1 - 3.2e-06 27.0 0.0 7.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 GAM29470.1 - 0.032 14.1 1.0 0.069 13.0 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Menin PF05053.13 GAM29470.1 - 5.1 5.3 18.9 4.2 5.6 5.3 2.1 2 0 0 2 2 2 0 Menin Histone PF00125.24 GAM29471.1 - 1.4e-09 38.4 0.1 1.7e-09 38.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DnaJ PF00226.31 GAM29472.1 - 2.9e-06 27.3 0.2 7.2e-06 26.0 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain SUIM_assoc PF16619.5 GAM29472.1 - 1.1e-05 25.4 4.4 2.3e-05 24.4 4.4 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Myc_N PF01056.18 GAM29472.1 - 0.00023 21.2 2.1 0.00029 20.8 2.1 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Spt20 PF12090.8 GAM29472.1 - 0.0029 17.2 12.3 0.0029 17.2 12.3 1.7 2 0 0 2 2 2 1 Spt20 family Plasmid_stab_B PF10784.9 GAM29472.1 - 0.049 13.5 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Plasmid stability protein Ndc1_Nup PF09531.10 GAM29472.1 - 0.064 12.0 3.0 0.067 11.9 3.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Androgen_recep PF02166.16 GAM29472.1 - 0.25 10.1 10.4 0.31 9.8 10.4 1.1 1 0 0 1 1 1 0 Androgen receptor DUF4834 PF16118.5 GAM29472.1 - 0.32 12.0 3.4 0.76 10.8 3.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Peroxin-3 PF04882.12 GAM29472.1 - 0.58 9.1 8.6 0.85 8.5 8.6 1.2 1 0 0 1 1 1 0 Peroxin-3 Cwf_Cwc_15 PF04889.12 GAM29472.1 - 0.84 9.3 14.6 1.3 8.7 14.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ASD2 PF08687.11 GAM29472.1 - 1.7 8.1 9.2 2 7.9 8.7 1.4 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 NOA36 PF06524.12 GAM29472.1 - 2.2 7.5 13.3 3.2 7.0 13.3 1.2 1 0 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 GAM29472.1 - 4.1 6.1 7.5 5.5 5.6 7.5 1.2 1 0 0 1 1 1 0 Presenilin DivIC PF04977.15 GAM29472.1 - 7.2 6.5 9.5 18 5.2 9.5 1.6 1 0 0 1 1 1 0 Septum formation initiator SAM_2 PF07647.17 GAM29473.1 - 0.00041 20.4 0.1 0.0014 18.7 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAM29473.1 - 0.00081 19.8 0.1 0.0014 19.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HSDR_N PF04313.14 GAM29473.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) Prominin PF05478.11 GAM29473.1 - 0.12 10.3 0.0 0.49 8.3 0.0 1.7 2 0 0 2 2 2 0 Prominin E7 PF00527.18 GAM29474.1 - 0.0097 16.1 3.3 0.019 15.1 3.3 1.5 1 0 0 1 1 1 1 E7 protein, Early protein SDA1 PF05285.12 GAM29474.1 - 0.011 15.2 5.4 0.014 14.8 5.4 1.1 1 0 0 1 1 1 0 SDA1 DUF4611 PF15387.6 GAM29474.1 - 0.015 15.5 11.6 0.026 14.7 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.13 GAM29474.1 - 0.016 15.1 4.9 0.025 14.5 4.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 GAM29474.1 - 0.026 12.6 14.1 0.035 12.2 14.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi GIY-YIG PF01541.24 GAM29474.1 - 0.047 14.0 0.2 0.098 12.9 0.2 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain Sporozoite_P67 PF05642.11 GAM29474.1 - 0.06 11.4 4.1 0.076 11.1 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 GAM29474.1 - 0.082 12.2 5.9 0.1 11.9 5.9 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 GAM29474.1 - 0.088 11.3 7.3 0.11 11.1 7.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Bcl-2_BAD PF10514.9 GAM29474.1 - 0.18 12.3 0.4 0.31 11.5 0.4 1.3 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD Nop14 PF04147.12 GAM29474.1 - 0.21 9.8 10.7 0.27 9.4 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 GAM29474.1 - 0.26 11.1 6.8 0.41 10.4 6.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 GAM29474.1 - 0.74 9.5 6.0 1.2 8.8 6.0 1.3 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.9 GAM29474.1 - 0.74 8.9 23.3 1.1 8.3 23.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GCIP PF13324.6 GAM29474.1 - 1.9 8.0 8.3 2.9 7.4 8.3 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC45 PF02724.14 GAM29474.1 - 4.8 5.4 12.7 7.2 4.8 12.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.8 GAM29474.1 - 4.9 6.0 7.9 6.8 5.5 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RVT_1 PF00078.27 GAM29475.1 - 5.9e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WH2 PF02205.20 GAM29478.1 - 0.0005 19.8 1.7 0.0005 19.8 1.7 1.8 2 0 0 2 2 2 1 WH2 motif Pkinase_Tyr PF07714.17 GAM29478.1 - 0.0008 18.8 0.0 0.0021 17.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAM29478.1 - 0.0034 16.8 0.5 0.013 14.9 0.5 1.9 1 1 0 1 1 1 1 Protein kinase domain DUF4064 PF13273.6 GAM29478.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DEC-1_N PF04625.13 GAM29478.1 - 5.4 5.9 15.9 9.2 5.2 15.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Totivirus_coat PF05518.11 GAM29478.1 - 8.4 4.3 6.3 12 3.8 6.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein Ctr PF04145.15 GAM29479.1 - 2.4e-26 93.1 6.0 7e-26 91.6 6.0 1.8 1 1 0 1 1 1 1 Ctr copper transporter family Prion_bPrPp PF11587.8 GAM29479.1 - 1.2 9.0 3.8 1.8 8.5 0.3 2.6 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal DDE_Tnp_4 PF13359.6 GAM29480.1 - 2.4e-25 89.0 0.0 2.8e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 GAM29480.1 - 7.3e-10 38.9 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain FNIP PF05725.12 GAM29483.1 - 7.2e-11 42.1 1.7 0.0062 16.7 0.0 5.1 4 2 0 4 4 4 3 FNIP Repeat LRR_5 PF13306.6 GAM29483.1 - 0.083 12.8 0.3 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LHC PF00556.20 GAM29483.1 - 0.18 12.0 0.8 0.93 9.8 0.1 2.4 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Peptidase_C48 PF02902.19 GAM29486.1 - 0.00075 19.4 1.5 0.0012 18.7 0.5 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain BUD22 PF09073.10 GAM29487.1 - 0.082 12.2 10.2 0.083 12.2 10.2 1.0 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 GAM29487.1 - 3.3 6.9 8.1 3.4 6.9 8.1 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GAM29487.1 - 4.4 5.5 9.0 4.4 5.5 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 GAM29487.1 - 7.6 7.0 14.5 1.8 9.0 10.7 1.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Exo_endo_phos_2 PF14529.6 GAM29488.1 - 0.0073 16.1 1.7 0.009 15.9 1.7 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF1179 PF06678.11 GAM29489.1 - 0.042 13.8 0.2 0.083 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) GUCT PF08152.12 GAM29490.1 - 0.031 14.6 0.0 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 GUCT (NUC152) domain Aminotran_1_2 PF00155.21 GAM29490.1 - 0.13 11.5 0.0 0.42 9.7 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class I and II DUF717 PF05338.12 GAM29491.1 - 0.0013 18.8 1.5 0.24 11.5 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF717) FlaC_arch PF05377.11 GAM29491.1 - 0.022 15.2 3.1 0.082 13.3 0.3 3.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) PI3K_P85_iSH2 PF16454.5 GAM29491.1 - 0.12 12.0 2.3 0.58 9.7 2.4 2.0 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Translin PF01997.16 GAM29491.1 - 0.3 11.0 0.1 0.3 11.0 0.1 2.5 2 1 0 2 2 2 0 Translin family HrpB7 PF09486.10 GAM29491.1 - 0.47 10.8 5.9 3.5 8.0 1.1 2.8 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 GAM29491.1 - 0.94 9.5 8.2 2 8.5 0.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 GAM29491.1 - 0.98 10.1 6.2 6.1 7.5 0.1 3.5 2 1 1 3 3 3 0 SlyX DUF5082 PF16888.5 GAM29491.1 - 1.4 9.2 7.6 15 5.9 0.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Ecl1 PF12855.7 GAM29491.1 - 1.8 9.7 26.5 4.8 8.3 26.5 1.7 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins AT_hook PF02178.19 GAM29491.1 - 2.2 8.4 6.0 5.3 7.3 6.0 1.7 1 0 0 1 1 1 0 AT hook motif Tektin PF03148.14 GAM29491.1 - 2.5 6.8 7.7 0.13 11.0 0.7 2.2 2 0 0 2 2 2 0 Tektin family DUF745 PF05335.13 GAM29491.1 - 2.7 7.7 13.4 0.048 13.4 3.3 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF745) Hc1 PF07432.13 GAM29491.1 - 3.2 8.1 14.3 0.67 10.3 1.5 2.6 2 0 0 2 2 2 0 Histone H1-like protein Hc1 Fzo_mitofusin PF04799.13 GAM29491.1 - 3.4 7.2 12.1 0.89 9.1 0.3 3.2 3 0 0 3 3 3 0 fzo-like conserved region Fib_alpha PF08702.10 GAM29491.1 - 5.4 7.2 15.6 18 5.5 1.1 4.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 GAM29491.1 - 6.5 6.8 10.7 0.68 10.0 1.6 3.1 3 0 0 3 3 3 0 Laminin Domain II AAA PF00004.29 GAM29492.1 - 1.1e-43 148.8 0.0 2.8e-43 147.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAM29492.1 - 7.2e-15 54.5 0.1 1.8e-14 53.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 GAM29492.1 - 1.8e-08 34.7 0.1 1.2e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAM29492.1 - 3e-06 27.3 0.0 1.1e-05 25.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAM29492.1 - 4.8e-06 27.1 0.0 0.00011 22.6 0.0 2.5 2 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 GAM29492.1 - 5.9e-05 23.4 1.8 0.012 15.8 1.1 2.9 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 GAM29492.1 - 9.9e-05 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_ID_OB PF16450.5 GAM29492.1 - 0.00024 21.0 0.3 0.00064 19.6 0.3 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain TIP49 PF06068.13 GAM29492.1 - 0.0011 18.2 0.0 0.0026 17.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 GAM29492.1 - 0.0015 18.7 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAM29492.1 - 0.0019 18.8 1.0 0.017 15.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 GAM29492.1 - 0.0024 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 GAM29492.1 - 0.005 16.7 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 GAM29492.1 - 0.0075 15.6 0.0 0.023 14.0 0.0 1.8 1 0 0 1 1 1 1 KaiC PhoH PF02562.16 GAM29492.1 - 0.008 15.6 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 GAM29492.1 - 0.0084 15.5 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAM29492.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAM29492.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MscS_porin PF12795.7 GAM29492.1 - 0.017 14.6 0.5 0.031 13.8 0.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain RNA_helicase PF00910.22 GAM29492.1 - 0.02 15.2 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 GAM29492.1 - 0.024 15.1 0.2 0.26 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAM29492.1 - 0.026 14.2 0.0 0.09 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GAM29492.1 - 0.028 13.6 0.0 0.068 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAM29492.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 GAM29492.1 - 0.038 13.7 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain APG6_N PF17675.1 GAM29492.1 - 0.039 14.5 3.2 0.11 13.1 3.2 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region ABC_tran PF00005.27 GAM29492.1 - 0.042 14.4 0.2 0.71 10.4 0.0 2.5 3 1 0 3 3 2 0 ABC transporter Parvo_NS1 PF01057.17 GAM29492.1 - 0.046 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 GAM29492.1 - 0.05 13.2 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 GAM29492.1 - 0.053 12.4 1.5 0.12 11.2 1.5 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_14 PF13173.6 GAM29492.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4435 PF14491.6 GAM29492.1 - 0.1 12.5 1.5 0.25 11.2 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) AAA_19 PF13245.6 GAM29492.1 - 0.11 12.8 0.1 0.67 10.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain SlyX PF04102.12 GAM29492.1 - 0.13 12.9 2.5 0.4 11.3 2.5 1.8 1 0 0 1 1 1 0 SlyX AAA_13 PF13166.6 GAM29492.1 - 0.15 10.7 1.4 6.7 5.2 1.4 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 GAM29492.1 - 0.18 11.6 3.2 0.26 11.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain DASH_Dad2 PF08654.10 GAM29492.1 - 0.23 11.9 2.4 0.57 10.6 1.9 1.9 2 0 0 2 2 1 0 DASH complex subunit Dad2 FlaC_arch PF05377.11 GAM29492.1 - 0.43 11.0 10.9 0.045 14.2 3.8 2.7 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 GAM29492.1 - 0.7 9.7 6.4 0.081 12.7 1.8 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF724) RVT_1 PF00078.27 GAM29493.1 - 9.1e-10 38.4 0.6 3.4e-09 36.6 0.6 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.24 GAM29497.1 - 1.4e-34 119.2 1.3 1.7e-34 119.0 1.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAM29497.1 - 2.1e-09 37.5 0.2 3.1e-09 36.9 0.2 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAM29497.1 - 1.6e-05 25.2 0.3 2.7e-05 24.5 0.3 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GAM29497.1 - 0.025 14.9 0.7 0.042 14.1 0.7 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAM_1 PF00536.30 GAM29498.1 - 0.0078 16.6 0.1 0.013 16.0 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 GAM29498.1 - 0.014 15.6 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Dimer_Tnp_hAT PF05699.14 GAM29499.1 - 6.7e-08 32.2 1.6 2.3e-07 30.5 0.1 2.7 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region Capsid_VP7 PF17071.5 GAM29499.1 - 0.088 12.1 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Outer capsid protein VP7 RT_RNaseH_2 PF17919.1 GAM29500.1 - 5.9e-27 93.6 0.0 2.3e-25 88.5 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 GAM29500.1 - 3.4e-26 91.6 0.0 3.8e-25 88.2 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 GAM29500.1 - 1.1e-13 51.0 0.1 3.5e-13 49.5 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 GAM29500.1 - 7.9e-13 48.6 0.0 3e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 GAM29500.1 - 6.6e-08 32.3 0.2 1.1e-06 28.3 0.1 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 GAM29500.1 - 1.4e-05 25.2 0.1 4.3e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF3848 PF12959.7 GAM29501.1 - 0.0028 17.7 0.3 0.039 14.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3848) Phage_integrase PF00589.22 GAM29503.1 - 1.4e-09 38.0 0.0 2.2e-09 37.3 0.0 1.3 1 1 1 2 2 2 1 Phage integrase family DUF4413 PF14372.6 GAM29504.1 - 0.0024 18.2 0.2 0.0052 17.1 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) Pkinase PF00069.25 GAM29506.1 - 1.1e-40 139.7 0.0 6.1e-16 58.6 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAM29506.1 - 1.8e-23 83.2 0.0 4.1e-09 36.1 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAM29506.1 - 0.015 14.1 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 GAM29506.1 - 0.031 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAM29506.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_C48 PF02902.19 GAM29507.1 - 0.00055 19.8 0.4 0.00055 19.8 0.4 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_S49_N PF08496.10 GAM29507.1 - 0.035 14.2 4.2 0.056 13.5 4.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Presenilin PF01080.17 GAM29507.1 - 2.7 6.7 4.5 3.8 6.2 4.5 1.1 1 0 0 1 1 1 0 Presenilin DUF4604 PF15377.6 GAM29511.1 - 2.7e-07 31.2 27.5 4.6e-07 30.4 27.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Kin17_mid PF10357.9 GAM29511.1 - 1.3 9.0 0.0 1.3 9.0 0.0 3.2 3 1 0 3 3 3 0 Domain of Kin17 curved DNA-binding protein IF2_assoc PF08364.11 GAM29511.1 - 1.7 9.0 0.0 1.7 9.0 0.0 3.3 3 1 0 3 3 3 0 Bacterial translation initiation factor IF-2 associated region # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Acytostelium_subglobosum-LB1-Asub_2.0/GCA_000787575.2_Asub_2.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Acytostelium_subglobosum-LB1-Asub_2.0/GCA_000787575.2_Asub_2.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Acytostelium_subglobosum-LB1-Asub_2.0/GCA_000787575.2_Asub_2.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Acytostelium_subglobosum-LB1-Asub_2.0/GCA_000787575.2_Asub_2.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 10:32:43 2019 # [ok]